TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 Gene3D G3DSA:3.40.50.300 3 214 5.9E-72 T 12-10-2018 TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 406 61.516 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 9.6E-16 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 SUPERFAMILY SSF50465 310 405 1.44E-36 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 SUPERFAMILY SSF52540 6 230 6.44E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 Gene3D G3DSA:2.40.30.10 350 405 8.2E-30 T 12-10-2018 TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 406 8.1E-224 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 PRINTS PR00315 GTP-binding elongation factor signature 14 27 6.4E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 PRINTS PR00315 GTP-binding elongation factor signature 95 106 6.4E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 PRINTS PR00315 GTP-binding elongation factor signature 79 89 6.4E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 PRINTS PR00315 GTP-binding elongation factor signature 132 141 6.4E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 PRINTS PR00315 GTP-binding elongation factor signature 59 67 6.4E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 Pfam PF03144 Elongation factor Tu domain 2 236 305 3.1E-18 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 SUPERFAMILY SSF50447 216 313 3.34E-32 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 Pfam PF00009 Elongation factor Tu GTP binding domain 10 212 7.2E-62 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 Pfam PF03143 Elongation factor Tu C-terminal domain 310 404 5.2E-35 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal TSC_c22460 7df6e360fdc5c05e3f8194dfff06a6e9 406 Gene3D G3DSA:2.40.30.10 217 346 5.4E-59 T 12-10-2018 TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 Gene3D G3DSA:3.40.50.300 3 214 5.9E-72 T 12-10-2018 TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 406 61.516 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 149 9.6E-16 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 SUPERFAMILY SSF50465 310 405 1.44E-36 T 12-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 SUPERFAMILY SSF52540 6 230 6.44E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 Gene3D G3DSA:2.40.30.10 350 405 8.2E-30 T 12-10-2018 TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 406 8.1E-224 T 12-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 PRINTS PR00315 GTP-binding elongation factor signature 14 27 6.4E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 PRINTS PR00315 GTP-binding elongation factor signature 95 106 6.4E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 PRINTS PR00315 GTP-binding elongation factor signature 79 89 6.4E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 PRINTS PR00315 GTP-binding elongation factor signature 132 141 6.4E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 PRINTS PR00315 GTP-binding elongation factor signature 59 67 6.4E-25 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 Pfam PF03144 Elongation factor Tu domain 2 236 305 3.1E-18 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 SUPERFAMILY SSF50447 216 313 3.34E-32 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 Pfam PF00009 Elongation factor Tu GTP binding domain 10 212 7.2E-62 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 Pfam PF03143 Elongation factor Tu C-terminal domain 310 404 5.2E-35 T 12-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal TSC_c01740 7df6e360fdc5c05e3f8194dfff06a6e9 406 Gene3D G3DSA:2.40.30.10 217 346 5.4E-59 T 12-10-2018 TSC_c17760 b6025ccd7c70c0bc2de8d683d7fc1310 334 Gene3D G3DSA:2.40.10.120 30 217 5.3E-25 T 12-10-2018 TSC_c17760 b6025ccd7c70c0bc2de8d683d7fc1310 334 Pfam PF13365 Trypsin-like peptidase domain 62 194 1.3E-16 T 12-10-2018 TSC_c17760 b6025ccd7c70c0bc2de8d683d7fc1310 334 SUPERFAMILY SSF50156 253 332 6.44E-17 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 TSC_c17760 b6025ccd7c70c0bc2de8d683d7fc1310 334 Gene3D G3DSA:2.30.42.10 228 331 2.4E-23 T 12-10-2018 TSC_c17760 b6025ccd7c70c0bc2de8d683d7fc1310 334 Pfam PF13180 PDZ domain 254 328 2.6E-13 T 12-10-2018 IPR001478 PDZ domain GO:0005515 TSC_c17760 b6025ccd7c70c0bc2de8d683d7fc1310 334 PRINTS PR00834 HtrA/DegQ protease family signature 277 289 1.4E-11 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c17760 b6025ccd7c70c0bc2de8d683d7fc1310 334 PRINTS PR00834 HtrA/DegQ protease family signature 131 155 1.4E-11 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c17760 b6025ccd7c70c0bc2de8d683d7fc1310 334 PRINTS PR00834 HtrA/DegQ protease family signature 70 82 1.4E-11 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c17760 b6025ccd7c70c0bc2de8d683d7fc1310 334 PRINTS PR00834 HtrA/DegQ protease family signature 91 111 1.4E-11 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c17760 b6025ccd7c70c0bc2de8d683d7fc1310 334 PRINTS PR00834 HtrA/DegQ protease family signature 187 204 1.4E-11 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c17760 b6025ccd7c70c0bc2de8d683d7fc1310 334 PRINTS PR00834 HtrA/DegQ protease family signature 165 182 1.4E-11 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c17760 b6025ccd7c70c0bc2de8d683d7fc1310 334 SMART SM00228 237 319 2.9E-5 T 12-10-2018 IPR001478 PDZ domain GO:0005515 TSC_c17760 b6025ccd7c70c0bc2de8d683d7fc1310 334 SUPERFAMILY SSF50494 40 211 1.98E-30 T 12-10-2018 IPR009003 Peptidase S1, PA clan TSC_c18790 c41734fc0dd31ec213b0c4da4606579f 417 Gene3D G3DSA:3.40.190.10 147 406 9.0E-86 T 12-10-2018 TSC_c18790 c41734fc0dd31ec213b0c4da4606579f 417 Gene3D G3DSA:3.40.190.10 38 370 9.0E-86 T 12-10-2018 TSC_c18790 c41734fc0dd31ec213b0c4da4606579f 417 SUPERFAMILY SSF53850 38 408 1.81E-73 T 12-10-2018 TSC_c18790 c41734fc0dd31ec213b0c4da4606579f 417 ProSitePatterns PS01037 Bacterial extracellular solute-binding proteins, family 1 signature. 142 159 - T 12-10-2018 IPR006061 Solute-binding family 1, conserved site GO:0055085 TSC_c18790 c41734fc0dd31ec213b0c4da4606579f 417 Pfam PF13416 Bacterial extracellular solute-binding protein 54 349 3.6E-47 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSC_c01280 7a19ccfd64088bda3ce602fe8ffd1ccc 196 Pfam PF13302 Acetyltransferase (GNAT) domain 14 144 4.2E-16 T 12-10-2018 IPR000182 GNAT domain TSC_c01280 7a19ccfd64088bda3ce602fe8ffd1ccc 196 Gene3D G3DSA:3.40.630.30 1 191 7.2E-53 T 12-10-2018 TSC_c01280 7a19ccfd64088bda3ce602fe8ffd1ccc 196 SUPERFAMILY SSF55729 5 171 1.18E-35 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSC_c21380 87a5aea5a023f04ae2ad64860a5456b5 602 Gene3D G3DSA:3.40.50.1820 346 602 4.2E-66 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c21380 87a5aea5a023f04ae2ad64860a5456b5 602 Pfam PF00326 Prolyl oligopeptidase family 396 601 3.2E-45 T 12-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 TSC_c21380 87a5aea5a023f04ae2ad64860a5456b5 602 Gene3D G3DSA:2.120.10.30 133 331 1.3E-5 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TSC_c21380 87a5aea5a023f04ae2ad64860a5456b5 602 SUPERFAMILY SSF82171 67 327 3.92E-15 T 12-10-2018 TSC_c21380 87a5aea5a023f04ae2ad64860a5456b5 602 SUPERFAMILY SSF53474 353 602 2.77E-63 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 SUPERFAMILY SSF88697 8 200 1.79E-37 T 12-10-2018 IPR015947 PUA-like superfamily TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 356 493 1.4E-20 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 SMART SM00382 352 497 9.5E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 SUPERFAMILY SSF52540 317 592 2.7E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 8 200 3.6E-36 T 12-10-2018 IPR003111 Lon, substrate-binding domain TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 TIGRFAM TIGR00763 lon: endopeptidase La 10 774 1.6E-282 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 Gene3D G3DSA:3.40.50.300 315 495 4.4E-65 T 12-10-2018 TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 Hamap MF_01973 Lon protease [lon]. 9 776 70.324 T 12-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 Gene3D G3DSA:3.30.230.10 597 779 1.0E-77 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 574 775 7.6E-92 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 PIRSF PIRSF001174 2 778 3.3E-304 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 Gene3D G3DSA:1.20.58.1480 119 245 4.2E-36 T 12-10-2018 TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 Gene3D G3DSA:1.10.8.60 496 588 4.4E-23 T 12-10-2018 TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 Gene3D G3DSA:2.30.130.40 2 114 9.0E-30 T 12-10-2018 TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 SMART SM00464 8 202 2.1E-56 T 12-10-2018 IPR003111 Lon, substrate-binding domain TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 599 615 4.9E-50 T 12-10-2018 TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 360 379 4.9E-50 T 12-10-2018 TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 707 726 4.9E-50 T 12-10-2018 TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 677 696 4.9E-50 T 12-10-2018 TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 730 748 4.9E-50 T 12-10-2018 TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 SUPERFAMILY SSF54211 599 774 2.66E-55 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c18360 ab25ba83c3c399849f915d03214f30f9 795 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 680 688 - T 12-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 TSC_c22720 b6cb4dc1dea051d4df0a23c8d8ff19f3 407 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 128 152 3.1E-15 T 12-10-2018 TSC_c22720 b6cb4dc1dea051d4df0a23c8d8ff19f3 407 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 10 26 3.1E-15 T 12-10-2018 TSC_c22720 b6cb4dc1dea051d4df0a23c8d8ff19f3 407 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 34 48 3.1E-15 T 12-10-2018 TSC_c22720 b6cb4dc1dea051d4df0a23c8d8ff19f3 407 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 90 102 3.1E-15 T 12-10-2018 TSC_c22720 b6cb4dc1dea051d4df0a23c8d8ff19f3 407 SUPERFAMILY SSF116734 230 397 1.96E-69 T 12-10-2018 TSC_c22720 b6cb4dc1dea051d4df0a23c8d8ff19f3 407 PIRSF PIRSF037236 1 407 8.6E-170 T 12-10-2018 IPR021188 N6 adenine-specific DNA methyltransferase, TaqI class TSC_c22720 b6cb4dc1dea051d4df0a23c8d8ff19f3 407 Pfam PF12950 TaqI-like C-terminal specificity domain 277 391 6.3E-13 T 12-10-2018 IPR025931 TaqI-like C-terminal specificity domain TSC_c22720 b6cb4dc1dea051d4df0a23c8d8ff19f3 407 SUPERFAMILY SSF53335 14 205 2.94E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c22720 b6cb4dc1dea051d4df0a23c8d8ff19f3 407 Pfam PF07669 Eco57I restriction-modification methylase 90 176 3.3E-5 T 12-10-2018 IPR011639 Restriction modification methylase Eco57I GO:0003677|GO:0003824|GO:0006304 TSC_c22720 b6cb4dc1dea051d4df0a23c8d8ff19f3 407 Gene3D G3DSA:3.40.50.150 13 208 3.2E-45 T 12-10-2018 TSC_c22720 b6cb4dc1dea051d4df0a23c8d8ff19f3 407 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 93 99 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TSC_c22720 b6cb4dc1dea051d4df0a23c8d8ff19f3 407 Gene3D G3DSA:3.90.220.10 230 398 2.4E-67 T 12-10-2018 IPR023135 N6 adenine-specific DNA methyltransferase, TaqI class, C-terminal TSC_c18820 e9f8150b33af0fd7b7f1727f50f7d023 184 SUPERFAMILY SSF53067 2 99 8.42E-20 T 12-10-2018 TSC_c18820 e9f8150b33af0fd7b7f1727f50f7d023 184 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 151 7.9E-32 T 12-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 TSC_c18820 e9f8150b33af0fd7b7f1727f50f7d023 184 Pfam PF00814 Glycoprotease family 32 133 2.5E-16 T 12-10-2018 IPR000905 Gcp-like domain TSC_c18820 e9f8150b33af0fd7b7f1727f50f7d023 184 Gene3D G3DSA:3.30.420.40 3 117 7.7E-24 T 12-10-2018 TSC_c09770 e80a51ad2932d19810f0ef76de25a822 184 SUPERFAMILY SSF50104 1 62 7.82E-17 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily TSC_c09770 e80a51ad2932d19810f0ef76de25a822 184 TIGRFAM TIGR00038 efp: translation elongation factor P 2 184 2.0E-72 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 TSC_c09770 e80a51ad2932d19810f0ef76de25a822 184 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 7.9E-22 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 TSC_c09770 e80a51ad2932d19810f0ef76de25a822 184 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 4 60 1.2E-19 T 12-10-2018 IPR013185 Translation elongation factor, KOW-like TSC_c09770 e80a51ad2932d19810f0ef76de25a822 184 ProSitePatterns PS01275 Elongation factor P signature. 149 168 - T 12-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site TSC_c09770 e80a51ad2932d19810f0ef76de25a822 184 Hamap MF_00141 Elongation factor P [efp]. 1 184 46.744 T 12-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 TSC_c09770 e80a51ad2932d19810f0ef76de25a822 184 SUPERFAMILY SSF50249 65 126 2.74E-18 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c09770 e80a51ad2932d19810f0ef76de25a822 184 Gene3D G3DSA:2.40.50.140 64 126 8.7E-28 T 12-10-2018 TSC_c09770 e80a51ad2932d19810f0ef76de25a822 184 Pfam PF09285 Elongation factor P, C-terminal 128 183 1.3E-27 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 TSC_c09770 e80a51ad2932d19810f0ef76de25a822 184 PIRSF PIRSF005901 1 184 2.9E-71 T 12-10-2018 IPR020599 Translation elongation factor P/YeiP TSC_c09770 e80a51ad2932d19810f0ef76de25a822 184 SUPERFAMILY SSF50249 128 184 3.86E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c09770 e80a51ad2932d19810f0ef76de25a822 184 SMART SM00841 128 183 3.7E-34 T 12-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 TSC_c09770 e80a51ad2932d19810f0ef76de25a822 184 Gene3D G3DSA:2.30.30.30 1 63 4.3E-28 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 TSC_c09770 e80a51ad2932d19810f0ef76de25a822 184 Gene3D G3DSA:2.40.50.140 127 184 5.2E-29 T 12-10-2018 TSC_c09770 e80a51ad2932d19810f0ef76de25a822 184 SMART SM01185 67 120 1.0E-25 T 12-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 118 147 - T 12-10-2018 IPR018239 NAD-dependent DNA ligase, active site TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 322 399 2.1E-32 T 12-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 PIRSF PIRSF001604 1 665 2.7E-244 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 SMART SM00278 510 529 8.1 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 SMART SM00278 444 463 17.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 SMART SM00278 478 497 69.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 SMART SM00278 542 561 14.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 Gene3D G3DSA:3.40.50.10190 585 673 1.2E-29 T 12-10-2018 IPR036420 BRCT domain superfamily TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 Gene3D G3DSA:1.10.287.610 1 76 8.4E-35 T 12-10-2018 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 5 319 7.7E-132 T 12-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 SUPERFAMILY SSF52113 586 666 3.63E-22 T 12-10-2018 IPR036420 BRCT domain superfamily TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 Gene3D G3DSA:1.10.150.20 503 584 3.9E-29 T 12-10-2018 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 657 2.7E-263 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 332 347 - T 12-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 SUPERFAMILY SSF56091 1 317 8.64E-117 T 12-10-2018 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 Gene3D G3DSA:1.10.150.20 430 502 1.2E-29 T 12-10-2018 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 Gene3D G3DSA:2.40.50.140 320 406 4.3E-32 T 12-10-2018 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 Gene3D G3DSA:3.30.470.30 122 253 3.3E-91 T 12-10-2018 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 SUPERFAMILY SSF47781 405 581 2.0E-62 T 12-10-2018 IPR010994 RuvA domain 2-like TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 Gene3D G3DSA:3.30.1490.70 84 313 3.3E-91 T 12-10-2018 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 Pfam PF12826 Helix-hairpin-helix motif 508 571 9.7E-20 T 12-10-2018 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 SMART SM00292 588 664 1.1E-18 T 12-10-2018 IPR001357 BRCT domain TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 Pfam PF14520 Helix-hairpin-helix domain 444 498 1.1E-6 T 12-10-2018 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 SMART SM00532 5 446 9.2E-290 T 12-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 SUPERFAMILY SSF50249 318 401 1.71E-27 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 Hamap MF_01588 DNA ligase [ligA]. 4 661 50.386 T 12-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 TSC_c17960 da2cce54b00f88e98e0b477a4d5bb95a 674 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 591 661 1.1E-14 T 12-10-2018 IPR001357 BRCT domain TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 Pfam PF03704 Bacterial transcriptional activator domain 114 250 2.1E-17 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 SUPERFAMILY SSF46894 11 88 2.62E-5 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 Gene3D G3DSA:1.25.40.10 634 840 7.6E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 SMART SM00028 1015 1048 120.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 SMART SM00028 166 199 1.2 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 SMART SM00028 735 768 390.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 SMART SM00028 118 151 410.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 SMART SM00028 701 734 0.29 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 SMART SM00028 1055 1088 100.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 SMART SM00028 893 926 14.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 SMART SM01043 113 250 1.6E-29 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 SUPERFAMILY SSF52540 270 518 3.93E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 SUPERFAMILY SSF48452 112 271 8.49E-23 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 Pfam PF13191 AAA ATPase domain 270 438 4.2E-23 T 12-10-2018 TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 Gene3D G3DSA:1.10.10.10 3 107 4.9E-12 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 SUPERFAMILY SSF48452 652 835 6.87E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 Gene3D G3DSA:1.25.40.10 865 1097 8.9E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 SUPERFAMILY SSF48452 869 1091 6.5E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 Gene3D G3DSA:1.25.40.10 113 263 5.4E-24 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 Gene3D G3DSA:3.40.50.300 264 444 3.2E-7 T 12-10-2018 TSC_c11660 c7b185bf70d2ac90433c49fe8ceabe80 1111 Pfam PF13181 Tetratricopeptide repeat 702 730 0.02 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c15320 e970a657b04baef81a02cdfa921a068f 381 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 17 381 8.0E-153 T 12-10-2018 TSC_c15320 e970a657b04baef81a02cdfa921a068f 381 Gene3D G3DSA:3.60.70.12 1 254 2.6E-90 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TSC_c15320 e970a657b04baef81a02cdfa921a068f 381 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 3 381 8.2E-121 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TSC_c15320 e970a657b04baef81a02cdfa921a068f 381 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 381 130.692 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TSC_c15320 e970a657b04baef81a02cdfa921a068f 381 SUPERFAMILY SSF56266 6 377 2.62E-130 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TSC_c15320 e970a657b04baef81a02cdfa921a068f 381 Gene3D G3DSA:3.10.20.340 255 381 4.7E-43 T 12-10-2018 TSC_c15320 e970a657b04baef81a02cdfa921a068f 381 Pfam PF01960 ArgJ family 11 381 5.7E-133 T 12-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TSC_c18680 4e06611d304e0cdc6dc5e8ff9e8f0387 202 Pfam PF01712 Deoxynucleoside kinase 3 195 9.2E-40 T 12-10-2018 IPR031314 Deoxynucleoside kinase domain TSC_c18680 4e06611d304e0cdc6dc5e8ff9e8f0387 202 SUPERFAMILY SSF52540 2 191 7.69E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c18680 4e06611d304e0cdc6dc5e8ff9e8f0387 202 Gene3D G3DSA:3.40.50.300 1 184 2.1E-49 T 12-10-2018 TSC_c18680 4e06611d304e0cdc6dc5e8ff9e8f0387 202 PIRSF PIRSF000705 1 200 3.4E-52 T 12-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 TSC_c17190 4afb04371125e68b61d5ca6e2df95f13 219 SMART SM00450 116 216 2.0E-25 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c17190 4afb04371125e68b61d5ca6e2df95f13 219 SMART SM00450 9 103 7.7E-25 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c17190 4afb04371125e68b61d5ca6e2df95f13 219 SUPERFAMILY SSF52821 114 219 1.13E-34 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c17190 4afb04371125e68b61d5ca6e2df95f13 219 SUPERFAMILY SSF52821 3 106 6.29E-37 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c17190 4afb04371125e68b61d5ca6e2df95f13 219 ProSitePatterns PS00380 Rhodanese signature 1. 144 155 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TSC_c17190 4afb04371125e68b61d5ca6e2df95f13 219 Pfam PF00581 Rhodanese-like domain 10 99 5.8E-18 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c17190 4afb04371125e68b61d5ca6e2df95f13 219 Pfam PF00581 Rhodanese-like domain 124 211 1.1E-16 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c17190 4afb04371125e68b61d5ca6e2df95f13 219 Gene3D G3DSA:3.40.250.10 11 119 2.9E-32 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c17190 4afb04371125e68b61d5ca6e2df95f13 219 Gene3D G3DSA:3.40.250.10 123 219 3.6E-31 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c03870 7fc1a352fa9f1ce1a7d445893d76b1e1 94 Gene3D G3DSA:1.20.58.1000 2 94 2.5E-31 T 12-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily TSC_c03870 7fc1a352fa9f1ce1a7d445893d76b1e1 94 Pfam PF02583 Metal-sensitive transcriptional repressor 13 92 1.1E-21 T 12-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 TSC_c14190 b6278c2a030a427eaeff8312a3039274 352 SUPERFAMILY SSF53383 3 346 1.05E-79 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c14190 b6278c2a030a427eaeff8312a3039274 352 PIRSF PIRSF000524 1 350 7.1E-82 T 12-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 TSC_c14190 b6278c2a030a427eaeff8312a3039274 352 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 176 196 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site TSC_c14190 b6278c2a030a427eaeff8312a3039274 352 Gene3D G3DSA:3.40.640.10 13 249 3.4E-118 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c14190 b6278c2a030a427eaeff8312a3039274 352 Pfam PF00266 Aminotransferase class-V 24 331 1.4E-24 T 12-10-2018 IPR000192 Aminotransferase class V domain TSC_c14190 b6278c2a030a427eaeff8312a3039274 352 Gene3D G3DSA:3.90.1150.10 4 331 3.4E-118 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 SUPERFAMILY SSF55681 2 256 5.47E-88 T 12-10-2018 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 Gene3D G3DSA:3.30.980.10 569 713 2.0E-51 T 12-10-2018 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 Gene3D G3DSA:3.10.310.40 783 881 3.5E-9 T 12-10-2018 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 665 714 2.0E-16 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 Pfam PF01411 tRNA synthetases class II (A) 5 568 1.3E-214 T 12-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 SUPERFAMILY SSF101353 258 472 3.4E-64 T 12-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 882 166.695 T 12-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 Gene3D G3DSA:3.30.54.20 636 695 2.0E-51 T 12-10-2018 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 SUPERFAMILY SSF55186 568 724 1.7E-48 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 Pfam PF02272 DHHA1 domain 750 880 2.8E-16 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 SMART SM00863 665 714 4.5E-18 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 Gene3D G3DSA:3.30.930.10 1 253 7.5E-98 T 12-10-2018 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 867 3.7E-269 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 4.4E-29 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 206 217 4.4E-29 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 237 250 4.4E-29 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 309 322 4.4E-29 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 PRINTS PR00980 Alanyl-tRNA synthetase signature 285 301 4.4E-29 T 12-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 SUPERFAMILY SSF50447 466 565 1.84E-19 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSC_c04010 cc5e61ec9c91b0cb4a983c605c4fe593 882 Gene3D G3DSA:2.40.30.130 473 565 3.2E-10 T 12-10-2018 TSC_c05330 73073a9c2559e1ad2fac6680e15bdca8 116 Pfam PF11497 NADH-quinone oxidoreductase chain 15 1 112 2.6E-54 T 12-10-2018 IPR021093 NADH-quinone oxidoreductase, subunit15 KEGG: 00190+1.6.5.11 TSC_c05330 73073a9c2559e1ad2fac6680e15bdca8 116 Gene3D G3DSA:3.30.920.80 1 116 6.6E-68 T 12-10-2018 IPR038458 NADH-quinone oxidoreductase, subunit 15 superfamily KEGG: 00190+1.6.5.11 TSC_c05330 73073a9c2559e1ad2fac6680e15bdca8 116 SUPERFAMILY SSF55387 1 116 1.52E-59 T 12-10-2018 TSC_c06380 4b0cb3896789ea904fcf7e536f7d55fe 333 Pfam PF02481 DNA recombination-mediator protein A 56 255 5.3E-69 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 TSC_c06380 4b0cb3896789ea904fcf7e536f7d55fe 333 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 66 263 7.4E-63 T 12-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 TSC_c06380 4b0cb3896789ea904fcf7e536f7d55fe 333 Gene3D G3DSA:3.40.50.450 1 266 1.0E-89 T 12-10-2018 TSC_c06380 4b0cb3896789ea904fcf7e536f7d55fe 333 SUPERFAMILY SSF102405 67 265 3.36E-39 T 12-10-2018 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 Gene3D G3DSA:2.20.25.90 249 303 2.9E-14 T 12-10-2018 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 Pfam PF00384 Molybdopterin oxidoreductase 305 409 7.7E-8 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 Pfam PF00384 Molybdopterin oxidoreductase 580 634 6.1E-6 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 Gene3D G3DSA:3.10.20.740 1 144 1.7E-29 T 12-10-2018 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 249 299 2.3E-9 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 SUPERFAMILY SSF54862 97 244 1.3E-32 T 12-10-2018 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 2 96 6.4E-13 T 12-10-2018 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 Gene3D G3DSA:3.40.50.740 310 377 2.4E-6 T 12-10-2018 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 180 190 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 Gene3D G3DSA:3.40.228.10 378 413 2.4E-6 T 12-10-2018 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 SUPERFAMILY SSF54292 2 95 4.56E-20 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 4 642 3.7E-145 T 12-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 Gene3D G3DSA:3.30.70.20 160 237 1.6E-7 T 12-10-2018 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 SUPERFAMILY SSF53706 247 657 3.87E-79 T 12-10-2018 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 SMART SM00926 249 303 6.6E-13 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 SUPERFAMILY SSF50692 686 766 1.04E-29 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 119 131 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 SMART SM00929 104 144 2.7E-16 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 106 141 1.1E-14 T 12-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05990 66cf660044a156738adb13214e0cc6b5 782 Gene3D G3DSA:3.40.50.740 573 679 7.2E-10 T 12-10-2018 TSC_c12900 6c1ae941b8e4e149745cb5bef0b7078c 432 Gene3D G3DSA:3.90.1150.10 10 421 2.1E-167 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c12900 6c1ae941b8e4e149745cb5bef0b7078c 432 Gene3D G3DSA:3.40.640.10 63 323 2.1E-167 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c12900 6c1ae941b8e4e149745cb5bef0b7078c 432 SUPERFAMILY SSF53383 23 426 8.21E-141 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c12900 6c1ae941b8e4e149745cb5bef0b7078c 432 PIRSF PIRSF000521 128 428 4.4E-40 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c12900 6c1ae941b8e4e149745cb5bef0b7078c 432 PIRSF PIRSF000521 23 132 2.0E-6 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c12900 6c1ae941b8e4e149745cb5bef0b7078c 432 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 240 277 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c12900 6c1ae941b8e4e149745cb5bef0b7078c 432 Pfam PF00202 Aminotransferase class-III 21 425 2.4E-129 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c12900 6c1ae941b8e4e149745cb5bef0b7078c 432 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 14 425 7.3E-171 T 12-10-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 TSC_c22240 1fdb753b68a5fdd2bfad627d32776847 438 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 424 8.3E-112 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSC_c22240 1fdb753b68a5fdd2bfad627d32776847 438 PIRSF PIRSF004557 1 434 1.2E-112 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSC_c22240 1fdb753b68a5fdd2bfad627d32776847 438 SUPERFAMILY SSF103491 1 419 1.83E-113 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSC_c22240 1fdb753b68a5fdd2bfad627d32776847 438 Pfam PF00344 SecY translocase 71 411 3.2E-103 T 12-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSC_c22240 1fdb753b68a5fdd2bfad627d32776847 438 Gene3D G3DSA:1.10.3370.10 1 424 6.7E-183 T 12-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSC_c22240 1fdb753b68a5fdd2bfad627d32776847 438 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 428 29.093 T 12-10-2018 IPR026593 Protein translocase subunit SecY TSC_c22240 1fdb753b68a5fdd2bfad627d32776847 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 151 176 2.0E-77 T 12-10-2018 TSC_c22240 1fdb753b68a5fdd2bfad627d32776847 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 269 288 2.0E-77 T 12-10-2018 TSC_c22240 1fdb753b68a5fdd2bfad627d32776847 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 111 134 2.0E-77 T 12-10-2018 TSC_c22240 1fdb753b68a5fdd2bfad627d32776847 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 70 90 2.0E-77 T 12-10-2018 TSC_c22240 1fdb753b68a5fdd2bfad627d32776847 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 309 331 2.0E-77 T 12-10-2018 TSC_c22240 1fdb753b68a5fdd2bfad627d32776847 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 397 415 2.0E-77 T 12-10-2018 TSC_c22240 1fdb753b68a5fdd2bfad627d32776847 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 2.0E-77 T 12-10-2018 TSC_c22240 1fdb753b68a5fdd2bfad627d32776847 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 177 200 2.0E-77 T 12-10-2018 TSC_c22240 1fdb753b68a5fdd2bfad627d32776847 438 PRINTS PR00303 Preprotein translocase SecY subunit signature 364 382 2.0E-77 T 12-10-2018 TSC_c23480 70b382b4cbeade58e044dff26c31edc7 612 Pfam PF02653 Branched-chain amino acid transport system / permease component 226 577 1.8E-29 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSC_c01310 4b6011ca877e048e9df65dda8b205329 411 Pfam PF02926 THUMP domain 57 162 2.1E-11 T 12-10-2018 IPR004114 THUMP domain GO:0003723 TSC_c01310 4b6011ca877e048e9df65dda8b205329 411 SUPERFAMILY SSF143437 8 172 2.09E-31 T 12-10-2018 TSC_c01310 4b6011ca877e048e9df65dda8b205329 411 SMART SM00981 76 164 1.6E-11 T 12-10-2018 IPR004114 THUMP domain GO:0003723 TSC_c01310 4b6011ca877e048e9df65dda8b205329 411 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 9 370 2.4E-99 T 12-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 TSC_c01310 4b6011ca877e048e9df65dda8b205329 411 Gene3D G3DSA:3.30.2130.30 1 172 5.9E-37 T 12-10-2018 TSC_c01310 4b6011ca877e048e9df65dda8b205329 411 SUPERFAMILY SSF52402 176 374 7.94E-51 T 12-10-2018 TSC_c01310 4b6011ca877e048e9df65dda8b205329 411 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 174 366 2.8E-70 T 12-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 TSC_c01310 4b6011ca877e048e9df65dda8b205329 411 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 411 121.467 T 12-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 TSC_c01310 4b6011ca877e048e9df65dda8b205329 411 Gene3D G3DSA:3.40.50.620 174 392 2.8E-73 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c15150 d3c9b437ac1ce35beeceb4d2d1021942 515 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 427 514 6.4E-10 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c15150 d3c9b437ac1ce35beeceb4d2d1021942 515 Gene3D G3DSA:3.30.565.10 389 515 1.1E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c15150 d3c9b437ac1ce35beeceb4d2d1021942 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 473 4.3E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c15150 d3c9b437ac1ce35beeceb4d2d1021942 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 501 514 4.3E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c15150 d3c9b437ac1ce35beeceb4d2d1021942 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 477 495 4.3E-5 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c15150 d3c9b437ac1ce35beeceb4d2d1021942 515 SMART SM00387 422 515 6.8E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c15150 d3c9b437ac1ce35beeceb4d2d1021942 515 SUPERFAMILY SSF55874 389 514 5.11E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c15150 d3c9b437ac1ce35beeceb4d2d1021942 515 Gene3D G3DSA:3.30.450.40 181 316 2.6E-8 T 12-10-2018 IPR029016 GAF-like domain superfamily TSC_c15150 d3c9b437ac1ce35beeceb4d2d1021942 515 Pfam PF07730 Histidine kinase 318 384 7.7E-20 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TSC_c15150 d3c9b437ac1ce35beeceb4d2d1021942 515 SUPERFAMILY SSF55781 182 322 1.74E-8 T 12-10-2018 TSC_c20090 196203ac395be10a5b719c54759fdb5c 477 Gene3D G3DSA:3.40.50.800 283 399 3.0E-32 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily TSC_c20090 196203ac395be10a5b719c54759fdb5c 477 Pfam PF09180 Prolyl-tRNA synthetase, C-terminal 410 477 2.0E-18 T 12-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TSC_c20090 196203ac395be10a5b719c54759fdb5c 477 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 9 477 1.4E-179 T 12-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TSC_c20090 196203ac395be10a5b719c54759fdb5c 477 SUPERFAMILY SSF64586 405 477 8.44E-23 T 12-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TSC_c20090 196203ac395be10a5b719c54759fdb5c 477 Gene3D G3DSA:3.30.930.10 1 282 8.0E-107 T 12-10-2018 TSC_c20090 196203ac395be10a5b719c54759fdb5c 477 SMART SM00946 410 477 4.1E-27 T 12-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TSC_c20090 196203ac395be10a5b719c54759fdb5c 477 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 102 270 2.7E-19 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c20090 196203ac395be10a5b719c54759fdb5c 477 Hamap MF_01571 Proline--tRNA ligase [proS]. 7 477 45.771 T 12-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TSC_c20090 196203ac395be10a5b719c54759fdb5c 477 SUPERFAMILY SSF52954 278 402 6.95E-35 T 12-10-2018 TSC_c20090 196203ac395be10a5b719c54759fdb5c 477 SUPERFAMILY SSF55681 13 276 8.64E-79 T 12-10-2018 TSC_c20090 196203ac395be10a5b719c54759fdb5c 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 145 156 4.3E-8 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TSC_c20090 196203ac395be10a5b719c54759fdb5c 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 4.3E-8 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TSC_c20090 196203ac395be10a5b719c54759fdb5c 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 4.3E-8 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TSC_c20090 196203ac395be10a5b719c54759fdb5c 477 PRINTS PR01046 Prolyl-tRNA synthetase signature 65 83 4.3E-8 T 12-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 TSC_c20090 196203ac395be10a5b719c54759fdb5c 477 Pfam PF03129 Anticodon binding domain 289 383 4.3E-18 T 12-10-2018 IPR004154 Anticodon-binding TSC_c20090 196203ac395be10a5b719c54759fdb5c 477 Gene3D G3DSA:3.30.110.30 404 477 6.7E-23 T 12-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 TSC_c06450 138db6fcb8dcfabb4144bcbeb98af610 201 Gene3D G3DSA:2.40.100.10 36 200 1.4E-49 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily TSC_c06450 138db6fcb8dcfabb4144bcbeb98af610 201 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 51 196 4.3E-40 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TSC_c06450 138db6fcb8dcfabb4144bcbeb98af610 201 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 159 174 3.1E-16 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TSC_c06450 138db6fcb8dcfabb4144bcbeb98af610 201 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 64 79 3.1E-16 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TSC_c06450 138db6fcb8dcfabb4144bcbeb98af610 201 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 131 146 3.1E-16 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TSC_c06450 138db6fcb8dcfabb4144bcbeb98af610 201 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 90 102 3.1E-16 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TSC_c06450 138db6fcb8dcfabb4144bcbeb98af610 201 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 146 158 3.1E-16 T 12-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 TSC_c06450 138db6fcb8dcfabb4144bcbeb98af610 201 SUPERFAMILY SSF50891 50 198 2.19E-48 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily TSC_c13320 3f80470362628524efaddd34cab19334 92 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 5 92 18.302 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 TSC_c13320 3f80470362628524efaddd34cab19334 92 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 8 92 3.3E-17 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 TSC_c13320 3f80470362628524efaddd34cab19334 92 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 22 87 6.1E-13 T 12-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 TSC_c13320 3f80470362628524efaddd34cab19334 92 SUPERFAMILY SSF141000 6 90 3.27E-18 T 12-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 TSC_c13320 3f80470362628524efaddd34cab19334 92 Gene3D G3DSA:1.10.20.60 1 47 1.8E-20 T 12-10-2018 TSC_c15380 b1594a3ca754aef5111710e4a9ce6387 333 ProSitePatterns PS00211 ABC transporters family signature. 113 127 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c15380 b1594a3ca754aef5111710e4a9ce6387 333 SUPERFAMILY SSF52540 18 218 3.63E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c15380 b1594a3ca754aef5111710e4a9ce6387 333 Pfam PF00005 ABC transporter 23 141 9.5E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c15380 b1594a3ca754aef5111710e4a9ce6387 333 SUPERFAMILY SSF50331 216 328 7.37E-12 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSC_c15380 b1594a3ca754aef5111710e4a9ce6387 333 Gene3D G3DSA:3.40.50.300 2 218 1.7E-59 T 12-10-2018 TSC_c15380 b1594a3ca754aef5111710e4a9ce6387 333 Gene3D G3DSA:2.40.50.140 227 326 4.2E-7 T 12-10-2018 TSC_c15380 b1594a3ca754aef5111710e4a9ce6387 333 SMART SM00382 19 189 2.0E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c15380 b1594a3ca754aef5111710e4a9ce6387 333 Gene3D G3DSA:2.40.50.100 253 323 4.2E-7 T 12-10-2018 TSC_c01780 5405a8d96827d449e7169d0e1d56cf20 147 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 4 140 30.86 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TSC_c01780 5405a8d96827d449e7169d0e1d56cf20 147 SMART SM00649 8 139 1.6E-86 T 12-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 TSC_c01780 5405a8d96827d449e7169d0e1d56cf20 147 SUPERFAMILY SSF54747 2 71 1.7E-28 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily TSC_c01780 5405a8d96827d449e7169d0e1d56cf20 147 Gene3D G3DSA:3.30.1550.10 1 71 2.5E-34 T 12-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily TSC_c01780 5405a8d96827d449e7169d0e1d56cf20 147 Pfam PF00298 Ribosomal protein L11, RNA binding domain 70 138 5.5E-28 T 12-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 TSC_c01780 5405a8d96827d449e7169d0e1d56cf20 147 SUPERFAMILY SSF46906 66 139 1.7E-28 T 12-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily TSC_c01780 5405a8d96827d449e7169d0e1d56cf20 147 Gene3D G3DSA:1.10.10.2720 72 147 1.9E-34 T 12-10-2018 TSC_c01780 5405a8d96827d449e7169d0e1d56cf20 147 ProSitePatterns PS00359 Ribosomal protein L11 signature. 125 140 - T 12-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c01780 5405a8d96827d449e7169d0e1d56cf20 147 Pfam PF03946 Ribosomal protein L11, N-terminal domain 8 65 2.5E-27 T 12-10-2018 IPR020784 Ribosomal protein L11, N-terminal TSC_c01780 5405a8d96827d449e7169d0e1d56cf20 147 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 35 72 4.0E-15 T 12-10-2018 TSC_c01780 5405a8d96827d449e7169d0e1d56cf20 147 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 2 139 5.5E-63 T 12-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c23770 c6ea0ea414affc63c09c87712c6179b7 248 Pfam PF02535 ZIP Zinc transporter 106 232 4.9E-12 T 12-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 TSC_c09100 016306eaf65b92f2b5048f0b90734c95 492 Gene3D G3DSA:3.30.300.310 389 491 2.3E-34 T 12-10-2018 TSC_c09100 016306eaf65b92f2b5048f0b90734c95 492 Gene3D G3DSA:3.40.50.12780 5 386 2.6E-106 T 12-10-2018 TSC_c09100 016306eaf65b92f2b5048f0b90734c95 492 SUPERFAMILY SSF56801 5 488 3.66E-149 T 12-10-2018 TSC_c09100 016306eaf65b92f2b5048f0b90734c95 492 Pfam PF00501 AMP-binding enzyme 12 393 6.2E-89 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSC_c09100 016306eaf65b92f2b5048f0b90734c95 492 Pfam PF13193 AMP-binding enzyme C-terminal domain 402 475 3.3E-23 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSC_c09100 016306eaf65b92f2b5048f0b90734c95 492 ProSitePatterns PS00455 Putative AMP-binding domain signature. 145 156 - T 12-10-2018 IPR020845 AMP-binding, conserved site TSC_c14600 4cdb2811dca4494aa6139aec52df4727 273 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 44 261 2.5E-35 T 12-10-2018 TSC_c14600 4cdb2811dca4494aa6139aec52df4727 273 Gene3D G3DSA:3.40.190.10 111 210 1.9E-34 T 12-10-2018 TSC_c14600 4cdb2811dca4494aa6139aec52df4727 273 SUPERFAMILY SSF53850 41 254 3.07E-26 T 12-10-2018 TSC_c14600 4cdb2811dca4494aa6139aec52df4727 273 Gene3D G3DSA:3.40.190.10 41 243 1.9E-34 T 12-10-2018 TSC_c23110 8aabb9efb99557ef7422ca1fac859ee6 230 ProSitePatterns PS00380 Rhodanese signature 1. 18 29 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TSC_c23110 8aabb9efb99557ef7422ca1fac859ee6 230 SUPERFAMILY SSF52821 120 229 1.07E-24 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c23110 8aabb9efb99557ef7422ca1fac859ee6 230 Gene3D G3DSA:3.40.250.10 119 229 1.4E-31 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c23110 8aabb9efb99557ef7422ca1fac859ee6 230 Pfam PF00581 Rhodanese-like domain 124 222 3.0E-11 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c23110 8aabb9efb99557ef7422ca1fac859ee6 230 Pfam PF00581 Rhodanese-like domain 8 98 4.1E-8 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c23110 8aabb9efb99557ef7422ca1fac859ee6 230 SUPERFAMILY SSF52821 5 99 2.23E-12 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c23110 8aabb9efb99557ef7422ca1fac859ee6 230 SMART SM00450 117 227 1.8E-20 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c23110 8aabb9efb99557ef7422ca1fac859ee6 230 SMART SM00450 1 105 0.031 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c23110 8aabb9efb99557ef7422ca1fac859ee6 230 Gene3D G3DSA:3.40.250.10 1 118 9.8E-28 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c16660 50749bd69c8d896063e3464adb0c017a 300 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 17 166 6.1E-32 T 12-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal TSC_c16660 50749bd69c8d896063e3464adb0c017a 300 SUPERFAMILY SSF56747 16 181 6.28E-32 T 12-10-2018 TSC_c16660 50749bd69c8d896063e3464adb0c017a 300 SMART SM00943 15 172 2.9E-43 T 12-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 775 4.6E-188 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 Gene3D G3DSA:3.30.930.10 486 679 1.5E-53 T 12-10-2018 TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 776 39.789 T 12-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 Gene3D G3DSA:3.30.70.380 691 782 1.3E-30 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 SUPERFAMILY SSF50249 42 146 1.64E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 SUPERFAMILY SSF46955 1 185 1.17E-10 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 Gene3D G3DSA:3.30.56.10 399 471 2.3E-25 T 12-10-2018 TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 Gene3D G3DSA:3.50.40.10 185 398 2.2E-83 T 12-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 SUPERFAMILY SSF56037 197 392 1.78E-65 T 12-10-2018 TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 Pfam PF03483 B3/4 domain 215 383 9.2E-60 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 Gene3D G3DSA:2.40.50.140 38 151 3.3E-53 T 12-10-2018 TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 SUPERFAMILY SSF55681 462 676 1.74E-47 T 12-10-2018 TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 Pfam PF03484 tRNA synthetase B5 domain 403 466 3.8E-17 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 Pfam PF03147 Ferredoxin-fold anticodon binding domain 689 776 3.6E-24 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 SUPERFAMILY SSF54991 684 775 9.55E-26 T 12-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 Gene3D G3DSA:3.30.56.10 1 177 3.3E-53 T 12-10-2018 TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 SUPERFAMILY SSF46955 400 470 2.38E-15 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 SMART SM00896 689 781 3.1E-35 T 12-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 SMART SM00874 399 466 8.2E-26 T 12-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 Pfam PF01588 Putative tRNA binding domain 45 137 1.3E-6 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TSC_c24920 b6bb94adf8c4bac65169d3945a848973 782 SMART SM00873 207 383 1.5E-77 T 12-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 TSC_c10950 13c7a658d30a5ce4d933bc5fee3f07ce 712 SMART SM00642 231 631 5.3E-100 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSC_c10950 13c7a658d30a5ce4d933bc5fee3f07ce 712 Gene3D G3DSA:2.60.40.10 14 115 3.4E-20 T 12-10-2018 IPR013783 Immunoglobulin-like fold TSC_c10950 13c7a658d30a5ce4d933bc5fee3f07ce 712 SUPERFAMILY SSF81296 19 113 2.4E-16 T 12-10-2018 IPR014756 Immunoglobulin E-set TSC_c10950 13c7a658d30a5ce4d933bc5fee3f07ce 712 Pfam PF00128 Alpha amylase, catalytic domain 289 598 6.2E-60 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSC_c10950 13c7a658d30a5ce4d933bc5fee3f07ce 712 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 18 77 4.1E-12 T 12-10-2018 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 TSC_c10950 13c7a658d30a5ce4d933bc5fee3f07ce 712 Gene3D G3DSA:3.20.20.80 218 633 5.0E-115 T 12-10-2018 TSC_c10950 13c7a658d30a5ce4d933bc5fee3f07ce 712 SUPERFAMILY SSF51445 215 638 3.96E-100 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TSC_c18150 b98802d57181b40cbf362891d07e314a 323 SUPERFAMILY SSF53067 1 298 3.89E-35 T 12-10-2018 TSC_c18150 b98802d57181b40cbf362891d07e314a 323 Gene3D G3DSA:3.30.420.40 3 303 9.8E-109 T 12-10-2018 TSC_c18150 b98802d57181b40cbf362891d07e314a 323 Pfam PF00814 Glycoprotease family 23 294 4.5E-91 T 12-10-2018 IPR000905 Gcp-like domain TSC_c18150 b98802d57181b40cbf362891d07e314a 323 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 294 1.4E-92 T 12-10-2018 IPR017861 Kae1/TsaD family TSC_c18150 b98802d57181b40cbf362891d07e314a 323 Gene3D G3DSA:3.30.420.40 126 281 9.8E-109 T 12-10-2018 TSC_c18150 b98802d57181b40cbf362891d07e314a 323 ProSitePatterns PS01016 Glycoprotease family signature. 95 115 - T 12-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 TSC_c18150 b98802d57181b40cbf362891d07e314a 323 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 301 3.7E-111 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 TSC_c18150 b98802d57181b40cbf362891d07e314a 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 151 172 4.4E-48 T 12-10-2018 IPR017861 Kae1/TsaD family TSC_c18150 b98802d57181b40cbf362891d07e314a 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 128 140 4.4E-48 T 12-10-2018 IPR017861 Kae1/TsaD family TSC_c18150 b98802d57181b40cbf362891d07e314a 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 75 95 4.4E-48 T 12-10-2018 IPR017861 Kae1/TsaD family TSC_c18150 b98802d57181b40cbf362891d07e314a 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 96 115 4.4E-48 T 12-10-2018 IPR017861 Kae1/TsaD family TSC_c18150 b98802d57181b40cbf362891d07e314a 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 255 264 4.4E-48 T 12-10-2018 IPR017861 Kae1/TsaD family TSC_c18150 b98802d57181b40cbf362891d07e314a 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 4.4E-48 T 12-10-2018 IPR017861 Kae1/TsaD family TSC_c18150 b98802d57181b40cbf362891d07e314a 323 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 320 61.547 T 12-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 TSC_c05470 64d7dcb4eecec74c65fc94f9a0b2a3c4 437 Gene3D G3DSA:3.40.630.10 4 426 5.9E-165 T 12-10-2018 TSC_c05470 64d7dcb4eecec74c65fc94f9a0b2a3c4 437 Pfam PF01546 Peptidase family M20/M25/M40 69 430 5.9E-34 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 TSC_c05470 64d7dcb4eecec74c65fc94f9a0b2a3c4 437 Pfam PF07687 Peptidase dimerisation domain 175 333 1.9E-24 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain TSC_c05470 64d7dcb4eecec74c65fc94f9a0b2a3c4 437 Gene3D G3DSA:3.30.70.360 178 347 5.9E-165 T 12-10-2018 TSC_c05470 64d7dcb4eecec74c65fc94f9a0b2a3c4 437 SUPERFAMILY SSF53187 3 434 4.57E-60 T 12-10-2018 TSC_c05810 b65fb5cfc5bd07a2a5d8f1271e66e7ae 396 Gene3D G3DSA:3.90.1150.10 22 389 5.0E-155 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c05810 b65fb5cfc5bd07a2a5d8f1271e66e7ae 396 SUPERFAMILY SSF53383 4 390 2.86E-102 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c05810 b65fb5cfc5bd07a2a5d8f1271e66e7ae 396 Pfam PF00155 Aminotransferase class I and II 50 385 9.8E-43 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSC_c05810 b65fb5cfc5bd07a2a5d8f1271e66e7ae 396 Gene3D G3DSA:3.40.640.10 68 284 5.0E-155 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c07910 8b669ecda29904a548992c30688d418f 338 Pfam PF07907 YibE/F-like protein 84 321 9.0E-67 T 12-10-2018 IPR012507 YibE/F-like TSC_c13880 6a3c3d9a1d8b90bea0673e34a788bcaf 72 Gene3D G3DSA:3.30.300.20 2 70 3.7E-8 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TSC_c13880 6a3c3d9a1d8b90bea0673e34a788bcaf 72 Pfam PF13083 KH domain 2 66 4.3E-20 T 12-10-2018 TSC_c13880 6a3c3d9a1d8b90bea0673e34a788bcaf 72 Hamap MF_00088 UPF0109 protein . 1 72 18.198 T 12-10-2018 IPR020627 Uncharacterised protein family UPF0109 TSC_c13880 6a3c3d9a1d8b90bea0673e34a788bcaf 72 SUPERFAMILY SSF54814 7 61 1.11E-6 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TSC_c11720 147df7cb81f94865ff96aca4c4263b1d 444 Gene3D G3DSA:3.40.50.300 5 186 4.7E-23 T 12-10-2018 TSC_c11720 147df7cb81f94865ff96aca4c4263b1d 444 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 243 421 7.6E-29 T 12-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 TSC_c11720 147df7cb81f94865ff96aca4c4263b1d 444 SUPERFAMILY SSF52540 5 197 9.31E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c11720 147df7cb81f94865ff96aca4c4263b1d 444 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 5 432 1.8E-121 T 12-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 TSC_c11720 147df7cb81f94865ff96aca4c4263b1d 444 SUPERFAMILY SSF52317 242 434 1.03E-27 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c11720 147df7cb81f94865ff96aca4c4263b1d 444 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 3 424 40.36 T 12-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 TSC_c11720 147df7cb81f94865ff96aca4c4263b1d 444 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 191 1.5E-18 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TSC_c20890 effda7f7b3423bed6a83e8483a336bab 434 Pfam PF00579 tRNA synthetases class I (W and Y) 37 290 1.4E-60 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c20890 effda7f7b3423bed6a83e8483a336bab 434 Gene3D G3DSA:3.10.290.10 348 423 6.3E-31 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TSC_c20890 effda7f7b3423bed6a83e8483a336bab 434 Gene3D G3DSA:3.40.50.620 10 225 1.6E-76 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c20890 effda7f7b3423bed6a83e8483a336bab 434 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 8 432 44.094 T 12-10-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 TSC_c20890 effda7f7b3423bed6a83e8483a336bab 434 SUPERFAMILY SSF52374 10 299 1.08E-80 T 12-10-2018 TSC_c20890 effda7f7b3423bed6a83e8483a336bab 434 SUPERFAMILY SSF55174 354 432 1.28E-16 T 12-10-2018 TSC_c20890 effda7f7b3423bed6a83e8483a336bab 434 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 12 431 9.6E-95 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TSC_c20890 effda7f7b3423bed6a83e8483a336bab 434 Gene3D G3DSA:1.10.240.10 226 342 1.4E-33 T 12-10-2018 TSC_c20890 effda7f7b3423bed6a83e8483a336bab 434 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 169 184 8.8E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TSC_c20890 effda7f7b3423bed6a83e8483a336bab 434 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 219 231 8.8E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TSC_c20890 effda7f7b3423bed6a83e8483a336bab 434 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 186 208 8.8E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TSC_c20890 effda7f7b3423bed6a83e8483a336bab 434 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 52 74 8.8E-25 T 12-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 TSC_c22180 1d8432f9acb23974f37586067c77cbbc 209 SUPERFAMILY SSF55174 3 209 2.88E-77 T 12-10-2018 TSC_c22180 1d8432f9acb23974f37586067c77cbbc 209 SMART SM00363 99 163 3.5E-22 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22180 1d8432f9acb23974f37586067c77cbbc 209 Pfam PF01479 S4 domain 100 146 9.2E-23 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22180 1d8432f9acb23974f37586067c77cbbc 209 Gene3D G3DSA:3.10.290.10 98 194 3.3E-94 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TSC_c22180 1d8432f9acb23974f37586067c77cbbc 209 SMART SM01390 3 98 1.3E-56 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TSC_c22180 1d8432f9acb23974f37586067c77cbbc 209 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 98 5.8E-32 T 12-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 TSC_c22180 1d8432f9acb23974f37586067c77cbbc 209 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 209 1.7E-77 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 TSC_c22180 1d8432f9acb23974f37586067c77cbbc 209 ProSitePatterns PS00632 Ribosomal protein S4 signature. 97 121 - T 12-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22180 1d8432f9acb23974f37586067c77cbbc 209 Gene3D G3DSA:1.10.1050.10 6 209 3.3E-94 T 12-10-2018 TSC_c22180 1d8432f9acb23974f37586067c77cbbc 209 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 209 37.653 T 12-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 TSC_c06330 c158a4ef89df0ea1d2bd9faf98f10179 381 Gene3D G3DSA:3.40.50.150 171 380 1.6E-62 T 12-10-2018 TSC_c06330 c158a4ef89df0ea1d2bd9faf98f10179 381 SUPERFAMILY SSF88697 3 66 8.7E-6 T 12-10-2018 IPR015947 PUA-like superfamily TSC_c06330 c158a4ef89df0ea1d2bd9faf98f10179 381 Gene3D G3DSA:2.30.130.10 1 68 5.4E-18 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 TSC_c06330 c158a4ef89df0ea1d2bd9faf98f10179 381 SUPERFAMILY SSF53335 78 376 4.56E-61 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c06330 c158a4ef89df0ea1d2bd9faf98f10179 381 Pfam PF02475 Met-10+ like-protein 109 251 1.4E-7 T 12-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 TSC_c06330 c158a4ef89df0ea1d2bd9faf98f10179 381 Gene3D G3DSA:3.30.750.80 69 170 2.3E-38 T 12-10-2018 TSC_c14060 0627be29cb001d61e9e3f664e8b54d43 404 Gene3D G3DSA:1.10.3120.10 113 401 3.9E-41 T 12-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 TSC_c14060 0627be29cb001d61e9e3f664e8b54d43 404 Hamap MF_00303 Trigger factor [tig]. 1 404 16.135 T 12-10-2018 IPR005215 Trigger factor GO:0015031 TSC_c14060 0627be29cb001d61e9e3f664e8b54d43 404 TIGRFAM TIGR00115 tig: trigger factor 11 397 1.8E-87 T 12-10-2018 IPR005215 Trigger factor GO:0015031 TSC_c14060 0627be29cb001d61e9e3f664e8b54d43 404 Pfam PF05697 Bacterial trigger factor protein (TF) 8 143 7.1E-33 T 12-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 TSC_c14060 0627be29cb001d61e9e3f664e8b54d43 404 SUPERFAMILY SSF54534 131 225 1.18E-6 T 12-10-2018 TSC_c14060 0627be29cb001d61e9e3f664e8b54d43 404 SUPERFAMILY SSF102735 5 125 1.01E-27 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 TSC_c14060 0627be29cb001d61e9e3f664e8b54d43 404 SUPERFAMILY SSF109998 227 400 1.7E-32 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily TSC_c14060 0627be29cb001d61e9e3f664e8b54d43 404 Gene3D G3DSA:3.10.50.40 149 225 3.9E-41 T 12-10-2018 TSC_c14060 0627be29cb001d61e9e3f664e8b54d43 404 PIRSF PIRSF003095 2 404 2.0E-77 T 12-10-2018 IPR005215 Trigger factor GO:0015031 TSC_c14060 0627be29cb001d61e9e3f664e8b54d43 404 Gene3D G3DSA:3.30.70.1050 1 112 1.2E-29 T 12-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 TSC_c14060 0627be29cb001d61e9e3f664e8b54d43 404 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 239 399 5.2E-31 T 12-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 TSC_c05320 eb276302f2f00ee1db39fb08c0061d5c 357 Gene3D G3DSA:3.20.20.70 111 342 7.1E-12 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c05320 eb276302f2f00ee1db39fb08c0061d5c 357 SUPERFAMILY SSF102114 104 340 6.93E-25 T 12-10-2018 TSC_c05320 eb276302f2f00ee1db39fb08c0061d5c 357 Pfam PF04055 Radical SAM superfamily 124 276 2.5E-12 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSC_c05320 eb276302f2f00ee1db39fb08c0061d5c 357 SMART SM00729 118 339 8.9E-25 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSC_c11220 220d352b9ac14280c731208fc3ce1c62 299 Gene3D G3DSA:3.40.50.720 1 164 1.3E-43 T 12-10-2018 TSC_c11220 220d352b9ac14280c731208fc3ce1c62 299 PIRSF PIRSF000103 1 294 2.2E-25 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 TSC_c11220 220d352b9ac14280c731208fc3ce1c62 299 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 165 274 1.1E-16 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TSC_c11220 220d352b9ac14280c731208fc3ce1c62 299 SMART SM01350 165 299 9.9E-4 T 12-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 TSC_c11220 220d352b9ac14280c731208fc3ce1c62 299 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 4 17 - T 12-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 TSC_c11220 220d352b9ac14280c731208fc3ce1c62 299 Gene3D G3DSA:1.10.1040.10 165 295 5.2E-35 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSC_c11220 220d352b9ac14280c731208fc3ce1c62 299 SUPERFAMILY SSF48179 163 293 1.43E-28 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSC_c11220 220d352b9ac14280c731208fc3ce1c62 299 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 2 152 2.9E-34 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TSC_c11220 220d352b9ac14280c731208fc3ce1c62 299 SUPERFAMILY SSF51735 2 153 4.35E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c06020 be8b489b009a2a55a7edfde024f95c4e 406 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 22 406 2.5E-170 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06020 be8b489b009a2a55a7edfde024f95c4e 406 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 59 70 - T 12-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06020 be8b489b009a2a55a7edfde024f95c4e 406 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 15 406 48.696 T 12-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06020 be8b489b009a2a55a7edfde024f95c4e 406 SUPERFAMILY SSF56762 32 406 3.14E-135 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06020 be8b489b009a2a55a7edfde024f95c4e 406 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 136 406 4.0E-114 T 12-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06020 be8b489b009a2a55a7edfde024f95c4e 406 Gene3D G3DSA:1.10.645.20 23 406 9.5E-175 T 12-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 SUPERFAMILY SSF48557 8 458 8.33E-148 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 PRINTS PR00149 Fumarate lyase superfamily signature 235 262 1.4E-25 T 12-10-2018 IPR000362 Fumarate lyase family TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 PRINTS PR00149 Fumarate lyase superfamily signature 279 295 1.4E-25 T 12-10-2018 IPR000362 Fumarate lyase family TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 PRINTS PR00149 Fumarate lyase superfamily signature 151 169 1.4E-25 T 12-10-2018 IPR000362 Fumarate lyase family TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 PRINTS PR00149 Fumarate lyase superfamily signature 104 122 1.4E-25 T 12-10-2018 IPR000362 Fumarate lyase family TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 ProSitePatterns PS00163 Fumarate lyases signature. 279 288 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 Hamap MF_00006 Argininosuccinate lyase [argH]. 4 457 43.402 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 TIGRFAM TIGR00838 argH: argininosuccinate lyase 5 459 2.7E-181 T 12-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 PRINTS PR00145 Argininosuccinate lyase family signature 235 259 4.7E-61 T 12-10-2018 TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 PRINTS PR00145 Argininosuccinate lyase family signature 146 166 4.7E-61 T 12-10-2018 TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 PRINTS PR00145 Argininosuccinate lyase family signature 314 333 4.7E-61 T 12-10-2018 TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 PRINTS PR00145 Argininosuccinate lyase family signature 197 213 4.7E-61 T 12-10-2018 TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 PRINTS PR00145 Argininosuccinate lyase family signature 279 295 4.7E-61 T 12-10-2018 TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 PRINTS PR00145 Argininosuccinate lyase family signature 103 125 4.7E-61 T 12-10-2018 TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 Pfam PF14698 Argininosuccinate lyase C-terminal 367 434 1.5E-21 T 12-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 Gene3D G3DSA:1.10.275.50 1 108 6.3E-40 T 12-10-2018 TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 Gene3D G3DSA:1.20.200.10 109 451 7.2E-155 T 12-10-2018 TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 Gene3D G3DSA:1.10.40.30 368 438 7.2E-155 T 12-10-2018 TSC_c02750 697e7cbf44a2de90f9c783a01f2961f8 462 Pfam PF00206 Lyase 8 304 3.3E-75 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal TSC_c15230 6de915e9d1f87c80a90bbffc62b6f28b 183 PIRSF PIRSF006305 1 182 5.8E-48 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 TSC_c15230 6de915e9d1f87c80a90bbffc62b6f28b 183 Hamap MF_00528 Septum formation protein Maf [maf]. 1 183 29.6 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 TSC_c15230 6de915e9d1f87c80a90bbffc62b6f28b 183 Gene3D G3DSA:3.90.950.10 1 180 3.6E-58 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TSC_c15230 6de915e9d1f87c80a90bbffc62b6f28b 183 TIGRFAM TIGR00172 maf: septum formation protein Maf 2 176 4.4E-44 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 TSC_c15230 6de915e9d1f87c80a90bbffc62b6f28b 183 Pfam PF02545 Maf-like protein 2 176 1.1E-49 T 12-10-2018 IPR003697 Maf-like protein GO:0047429 TSC_c15230 6de915e9d1f87c80a90bbffc62b6f28b 183 SUPERFAMILY SSF52972 2 178 6.47E-52 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TSC_c21140 436cc1c7d6512751d8fefec5a6184b66 316 SMART SM00382 23 206 6.5E-19 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c21140 436cc1c7d6512751d8fefec5a6184b66 316 SUPERFAMILY SSF52540 6 235 5.59E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c21140 436cc1c7d6512751d8fefec5a6184b66 316 Pfam PF00005 ABC transporter 17 156 1.1E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c21140 436cc1c7d6512751d8fefec5a6184b66 316 Gene3D G3DSA:3.40.50.300 15 255 2.3E-72 T 12-10-2018 TSC_c21140 436cc1c7d6512751d8fefec5a6184b66 316 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c20250 f84cfff00efeca6a2dffca3e4f6b0aea 97 SUPERFAMILY SSF47729 7 96 3.09E-31 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TSC_c20250 f84cfff00efeca6a2dffca3e4f6b0aea 97 Pfam PF00216 Bacterial DNA-binding protein 7 96 1.4E-34 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSC_c20250 f84cfff00efeca6a2dffca3e4f6b0aea 97 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 52 71 - T 12-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 TSC_c20250 f84cfff00efeca6a2dffca3e4f6b0aea 97 PRINTS PR01727 Prokaryotic integration host factor signature 46 61 4.0E-15 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSC_c20250 f84cfff00efeca6a2dffca3e4f6b0aea 97 PRINTS PR01727 Prokaryotic integration host factor signature 64 77 4.0E-15 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSC_c20250 f84cfff00efeca6a2dffca3e4f6b0aea 97 PRINTS PR01727 Prokaryotic integration host factor signature 80 94 4.0E-15 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSC_c20250 f84cfff00efeca6a2dffca3e4f6b0aea 97 Gene3D G3DSA:4.10.520.10 2 97 5.0E-39 T 12-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 TSC_c20250 f84cfff00efeca6a2dffca3e4f6b0aea 97 SMART SM00411 7 96 1.6E-43 T 12-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 TSC_c12350 1221da6dd7b549d2a39e5951368b3399 696 SUPERFAMILY SSF53098 284 696 2.53E-47 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c12350 1221da6dd7b549d2a39e5951368b3399 696 Gene3D G3DSA:3.40.50.2300 327 477 4.8E-264 T 12-10-2018 TSC_c12350 1221da6dd7b549d2a39e5951368b3399 696 Gene3D G3DSA:2.170.260.50 177 267 4.8E-264 T 12-10-2018 TSC_c12350 1221da6dd7b549d2a39e5951368b3399 696 SMART SM00950 415 682 2.1E-7 T 12-10-2018 IPR003165 Piwi domain GO:0003676 TSC_c12350 1221da6dd7b549d2a39e5951368b3399 696 Pfam PF02171 Piwi domain 515 677 3.4E-9 T 12-10-2018 IPR003165 Piwi domain GO:0003676 TSC_c12350 1221da6dd7b549d2a39e5951368b3399 696 Gene3D G3DSA:3.30.70.2620 16 86 4.8E-264 T 12-10-2018 TSC_c12350 1221da6dd7b549d2a39e5951368b3399 696 Gene3D G3DSA:3.30.420.10 323 695 4.8E-264 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSC_c12350 1221da6dd7b549d2a39e5951368b3399 696 Gene3D G3DSA:3.30.530.60 3 594 4.8E-264 T 12-10-2018 TSC_c21060 47449e4d5ba03c9a71ede63f7d0f0fb9 180 Gene3D G3DSA:1.10.760.10 17 179 2.0E-49 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c21060 47449e4d5ba03c9a71ede63f7d0f0fb9 180 TIGRFAM TIGR04485 thiosulf_SoxX: sulfur oxidation c-type cytochrome SoxX 93 172 5.2E-24 T 12-10-2018 IPR030999 Sulfur oxidation c-type cytochrome SoxX TSC_c21060 47449e4d5ba03c9a71ede63f7d0f0fb9 180 PIRSF PIRSF024608 1 179 1.9E-72 T 12-10-2018 IPR016823 Sulfur oxidation c-type cytochrome SoxX, type II TSC_c21060 47449e4d5ba03c9a71ede63f7d0f0fb9 180 Pfam PF00034 Cytochrome c 83 171 5.7E-5 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c21060 47449e4d5ba03c9a71ede63f7d0f0fb9 180 SUPERFAMILY SSF46626 77 171 1.58E-16 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c18910 a53f456449f6ff506ce55f9bf474d531 251 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 185 201 - T 12-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 TSC_c18910 a53f456449f6ff506ce55f9bf474d531 251 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 1 249 8.5E-64 T 12-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 TSC_c18910 a53f456449f6ff506ce55f9bf474d531 251 PIRSF PIRSF005902 1 251 5.6E-56 T 12-10-2018 IPR001130 TatD family GO:0016788 TSC_c18910 a53f456449f6ff506ce55f9bf474d531 251 Gene3D G3DSA:3.20.20.140 1 250 1.2E-70 T 12-10-2018 TSC_c18910 a53f456449f6ff506ce55f9bf474d531 251 SUPERFAMILY SSF51556 1 250 1.12E-66 T 12-10-2018 IPR032466 Metal-dependent hydrolase TSC_c18910 a53f456449f6ff506ce55f9bf474d531 251 Pfam PF01026 TatD related DNase 2 248 1.4E-61 T 12-10-2018 IPR001130 TatD family GO:0016788 TSC_c23420 3fc9b6d0f4e7a8babe9e25a632aef151 603 PIRSF PIRSF005814 1 588 8.2E-170 T 12-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 TSC_c23420 3fc9b6d0f4e7a8babe9e25a632aef151 603 SMART SM00533 8 297 6.6E-12 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 TSC_c23420 3fc9b6d0f4e7a8babe9e25a632aef151 603 SUPERFAMILY SSF48334 20 273 1.14E-22 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily TSC_c23420 3fc9b6d0f4e7a8babe9e25a632aef151 603 SUPERFAMILY SSF52540 284 491 1.1E-44 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c23420 3fc9b6d0f4e7a8babe9e25a632aef151 603 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 389 405 - T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TSC_c23420 3fc9b6d0f4e7a8babe9e25a632aef151 603 Pfam PF00488 MutS domain V 312 491 2.1E-39 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TSC_c23420 3fc9b6d0f4e7a8babe9e25a632aef151 603 Gene3D G3DSA:3.40.50.300 277 575 7.9E-78 T 12-10-2018 TSC_c23420 3fc9b6d0f4e7a8babe9e25a632aef151 603 SMART SM00534 308 492 2.0E-73 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TSC_c19280 bca853ce64e06a5d875acf174c36e93e 322 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 85 96 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSC_c19280 bca853ce64e06a5d875acf174c36e93e 322 SUPERFAMILY SSF56059 118 321 6.01E-56 T 12-10-2018 TSC_c19280 bca853ce64e06a5d875acf174c36e93e 322 Gene3D G3DSA:3.30.1490.20 135 191 7.7E-82 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSC_c19280 bca853ce64e06a5d875acf174c36e93e 322 SUPERFAMILY SSF52440 5 117 2.01E-29 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSC_c19280 bca853ce64e06a5d875acf174c36e93e 322 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 264 291 - T 12-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSC_c19280 bca853ce64e06a5d875acf174c36e93e 322 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 321 38.878 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSC_c19280 bca853ce64e06a5d875acf174c36e93e 322 Gene3D G3DSA:3.40.50.20 4 107 1.4E-33 T 12-10-2018 TSC_c19280 bca853ce64e06a5d875acf174c36e93e 322 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 320 1.9E-95 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSC_c19280 bca853ce64e06a5d875acf174c36e93e 322 Pfam PF07478 D-ala D-ala ligase C-terminus 126 318 5.4E-63 T 12-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSC_c19280 bca853ce64e06a5d875acf174c36e93e 322 Pfam PF01820 D-ala D-ala ligase N-terminus 5 107 7.8E-22 T 12-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSC_c19280 bca853ce64e06a5d875acf174c36e93e 322 Gene3D G3DSA:3.30.470.20 112 319 7.7E-82 T 12-10-2018 TSC_c19280 bca853ce64e06a5d875acf174c36e93e 322 PIRSF PIRSF039102 1 322 1.0E-96 T 12-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSC_c12930 f69ade3a158f8002db366508409c2903 443 Pfam PF00202 Aminotransferase class-III 26 432 5.0E-93 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c12930 f69ade3a158f8002db366508409c2903 443 Gene3D G3DSA:3.90.1150.10 9 431 3.9E-140 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c12930 f69ade3a158f8002db366508409c2903 443 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 240 277 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c12930 f69ade3a158f8002db366508409c2903 443 SUPERFAMILY SSF53383 9 434 2.34E-122 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c12930 f69ade3a158f8002db366508409c2903 443 Gene3D G3DSA:3.40.640.10 58 325 3.9E-140 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c07180 6b1a654217014cca9a9f188abb957c71 455 Gene3D G3DSA:3.30.70.2740 333 413 1.5E-15 T 12-10-2018 TSC_c07180 6b1a654217014cca9a9f188abb957c71 455 SUPERFAMILY SSF55103 218 455 1.34E-66 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TSC_c07180 6b1a654217014cca9a9f188abb957c71 455 Gene3D G3DSA:3.30.465.40 13 228 4.6E-59 T 12-10-2018 TSC_c07180 6b1a654217014cca9a9f188abb957c71 455 SUPERFAMILY SSF56176 15 215 4.58E-58 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSC_c07180 6b1a654217014cca9a9f188abb957c71 455 Pfam PF01565 FAD binding domain 46 184 1.2E-40 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TSC_c07180 6b1a654217014cca9a9f188abb957c71 455 Pfam PF02913 FAD linked oxidases, C-terminal domain 215 453 6.3E-72 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TSC_c07180 6b1a654217014cca9a9f188abb957c71 455 Gene3D G3DSA:1.10.45.10 414 454 1.2E-14 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TSC_c07340 835a7d4d8baec9332835b9593206a177 637 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 452 609 5.2E-29 T 12-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c07340 835a7d4d8baec9332835b9593206a177 637 Gene3D G3DSA:3.30.420.10 452 610 1.5E-46 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSC_c07340 835a7d4d8baec9332835b9593206a177 637 SMART SM00479 452 614 5.8E-46 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TSC_c07340 835a7d4d8baec9332835b9593206a177 637 Pfam PF00929 Exonuclease 455 605 6.5E-31 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TSC_c07340 835a7d4d8baec9332835b9593206a177 637 SUPERFAMILY SSF55785 130 226 8.67E-6 T 12-10-2018 IPR035965 PAS domain superfamily TSC_c07340 835a7d4d8baec9332835b9593206a177 637 SUPERFAMILY SSF53098 452 622 9.59E-49 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c13240 7df14be35e185a976b14c55c635a493a 281 Pfam PF02645 Uncharacterised protein, DegV family COG1307 6 277 2.0E-61 T 12-10-2018 IPR003797 DegV TSC_c13240 7df14be35e185a976b14c55c635a493a 281 SUPERFAMILY SSF82549 6 278 1.91E-59 T 12-10-2018 TSC_c13240 7df14be35e185a976b14c55c635a493a 281 Gene3D G3DSA:3.30.1180.10 154 279 3.4E-19 T 12-10-2018 TSC_c13240 7df14be35e185a976b14c55c635a493a 281 Gene3D G3DSA:3.40.50.10170 6 153 4.3E-40 T 12-10-2018 TSC_c13240 7df14be35e185a976b14c55c635a493a 281 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 8 277 1.6E-64 T 12-10-2018 IPR003797 DegV TSC_c12720 1edf086031acb9150733946fe74c2e3e 512 Gene3D G3DSA:2.40.100.10 78 210 3.7E-53 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily TSC_c12720 1edf086031acb9150733946fe74c2e3e 512 SUPERFAMILY SSF50891 80 201 1.37E-38 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily TSC_c12720 1edf086031acb9150733946fe74c2e3e 512 SMART SM00796 2 191 4.0E-63 T 12-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D TSC_c12720 1edf086031acb9150733946fe74c2e3e 512 SMART SM00797 246 504 2.5E-58 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TSC_c12720 1edf086031acb9150733946fe74c2e3e 512 SUPERFAMILY SSF160467 3 84 5.89E-13 T 12-10-2018 TSC_c12720 1edf086031acb9150733946fe74c2e3e 512 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 5 191 3.1E-58 T 12-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D TSC_c12720 1edf086031acb9150733946fe74c2e3e 512 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 6 199 1.4E-44 T 12-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TSC_c12720 1edf086031acb9150733946fe74c2e3e 512 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 247 494 6.7E-60 T 12-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B TSC_c12720 1edf086031acb9150733946fe74c2e3e 512 Gene3D G3DSA:2.40.100.10 386 495 2.1E-32 T 12-10-2018 IPR029000 Cyclophilin-like domain superfamily TSC_c12720 1edf086031acb9150733946fe74c2e3e 512 Gene3D G3DSA:3.30.1360.40 1 71 8.3E-27 T 12-10-2018 TSC_c00690 3ade6ec148451d8a5b33214aac828e3d 492 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 2 291 2.4E-107 T 12-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 TSC_c00690 3ade6ec148451d8a5b33214aac828e3d 492 Pfam PF13177 DNA polymerase III, delta subunit 18 174 4.5E-43 T 12-10-2018 TSC_c00690 3ade6ec148451d8a5b33214aac828e3d 492 Gene3D G3DSA:3.40.50.300 11 173 2.4E-92 T 12-10-2018 TSC_c00690 3ade6ec148451d8a5b33214aac828e3d 492 SUPERFAMILY SSF52540 27 217 9.77E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c00690 3ade6ec148451d8a5b33214aac828e3d 492 Gene3D G3DSA:1.10.8.60 6 234 2.4E-92 T 12-10-2018 TSC_c00690 3ade6ec148451d8a5b33214aac828e3d 492 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 39 57 3.7E-6 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TSC_c00690 3ade6ec148451d8a5b33214aac828e3d 492 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 120 138 3.7E-6 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TSC_c00690 3ade6ec148451d8a5b33214aac828e3d 492 SMART SM00382 35 181 1.0E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c00690 3ade6ec148451d8a5b33214aac828e3d 492 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 228 290 4.4E-6 T 12-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 TSC_c15580 7d99ff19dfbb3de9f245ca5d7bf97233 223 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 208 1.2E-55 T 12-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 TSC_c15580 7d99ff19dfbb3de9f245ca5d7bf97233 223 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 221 5.9E-83 T 12-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TSC_c15580 7d99ff19dfbb3de9f245ca5d7bf97233 223 Gene3D G3DSA:3.20.20.70 1 223 2.5E-92 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c15580 7d99ff19dfbb3de9f245ca5d7bf97233 223 Hamap MF_00494 Probable transaldolase [tal]. 1 223 43.589 T 12-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 TSC_c15580 7d99ff19dfbb3de9f245ca5d7bf97233 223 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 TSC_c15580 7d99ff19dfbb3de9f245ca5d7bf97233 223 ProSitePatterns PS00958 Transaldolase active site. 89 106 - T 12-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 TSC_c15580 7d99ff19dfbb3de9f245ca5d7bf97233 223 SUPERFAMILY SSF51569 1 221 2.83E-72 T 12-10-2018 TSC_c12310 81d7e7a63013a84e4dc1beee143eb454 754 SUPERFAMILY SSF55073 336 489 1.18E-47 T 12-10-2018 IPR029787 Nucleotide cyclase TSC_c12310 81d7e7a63013a84e4dc1beee143eb454 754 SUPERFAMILY SSF141868 508 747 4.71E-73 T 12-10-2018 IPR035919 EAL domain superfamily TSC_c12310 81d7e7a63013a84e4dc1beee143eb454 754 SMART SM00052 502 743 1.3E-84 T 12-10-2018 IPR001633 EAL domain TSC_c12310 81d7e7a63013a84e4dc1beee143eb454 754 SMART SM00267 320 492 8.0E-58 T 12-10-2018 IPR000160 GGDEF domain TSC_c12310 81d7e7a63013a84e4dc1beee143eb454 754 Pfam PF00563 EAL domain 508 738 2.9E-62 T 12-10-2018 IPR001633 EAL domain TSC_c12310 81d7e7a63013a84e4dc1beee143eb454 754 Pfam PF13185 GAF domain 10 155 4.2E-10 T 12-10-2018 IPR003018 GAF domain GO:0005515 TSC_c12310 81d7e7a63013a84e4dc1beee143eb454 754 Pfam PF00990 Diguanylate cyclase, GGDEF domain 331 486 2.3E-44 T 12-10-2018 IPR000160 GGDEF domain TSC_c12310 81d7e7a63013a84e4dc1beee143eb454 754 SMART SM00065 10 165 0.0061 T 12-10-2018 IPR003018 GAF domain GO:0005515 TSC_c12310 81d7e7a63013a84e4dc1beee143eb454 754 SUPERFAMILY SSF55781 10 167 9.16E-15 T 12-10-2018 TSC_c12310 81d7e7a63013a84e4dc1beee143eb454 754 Gene3D G3DSA:3.30.450.40 1 169 7.4E-18 T 12-10-2018 IPR029016 GAF-like domain superfamily TSC_c12310 81d7e7a63013a84e4dc1beee143eb454 754 Gene3D G3DSA:3.30.70.270 325 494 1.9E-55 T 12-10-2018 TSC_c12310 81d7e7a63013a84e4dc1beee143eb454 754 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 330 487 1.1E-41 T 12-10-2018 IPR000160 GGDEF domain TSC_c12310 81d7e7a63013a84e4dc1beee143eb454 754 Gene3D G3DSA:3.20.20.450 503 748 2.7E-80 T 12-10-2018 IPR035919 EAL domain superfamily TSC_c10120 1d84f61577fc460937a9d66539fd44d5 380 Gene3D G3DSA:1.10.443.10 176 367 1.4E-47 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSC_c10120 1d84f61577fc460937a9d66539fd44d5 380 Gene3D G3DSA:1.10.150.130 62 169 6.2E-20 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal TSC_c10120 1d84f61577fc460937a9d66539fd44d5 380 Pfam PF00589 Phage integrase family 171 358 3.4E-27 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSC_c10120 1d84f61577fc460937a9d66539fd44d5 380 SUPERFAMILY SSF56349 65 361 3.53E-63 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSC_c10120 1d84f61577fc460937a9d66539fd44d5 380 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 76 144 3.6E-9 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TSC_c20700 4024ecf0b7538b780f1a153b6cea713c 754 PRINTS PR00811 Bacterial general secretion pathway protein D signature 713 731 8.5E-9 T 12-10-2018 IPR001775 GspD/PilQ family TSC_c20700 4024ecf0b7538b780f1a153b6cea713c 754 PRINTS PR00811 Bacterial general secretion pathway protein D signature 588 612 8.5E-9 T 12-10-2018 IPR001775 GspD/PilQ family TSC_c20700 4024ecf0b7538b780f1a153b6cea713c 754 PRINTS PR00811 Bacterial general secretion pathway protein D signature 516 526 8.5E-9 T 12-10-2018 IPR001775 GspD/PilQ family TSC_c20700 4024ecf0b7538b780f1a153b6cea713c 754 PRINTS PR00811 Bacterial general secretion pathway protein D signature 736 750 8.5E-9 T 12-10-2018 IPR001775 GspD/PilQ family TSC_c20700 4024ecf0b7538b780f1a153b6cea713c 754 Pfam PF00263 Bacterial type II and III secretion system protein 592 749 8.4E-38 T 12-10-2018 IPR004846 Type II/III secretion system GO:0009306 TSC_c20700 4024ecf0b7538b780f1a153b6cea713c 754 Pfam PF03958 Bacterial type II/III secretion system short domain 389 448 1.8E-7 T 12-10-2018 IPR005644 NolW-like TSC_c20700 4024ecf0b7538b780f1a153b6cea713c 754 Pfam PF03958 Bacterial type II/III secretion system short domain 455 532 2.9E-16 T 12-10-2018 IPR005644 NolW-like TSC_c20700 4024ecf0b7538b780f1a153b6cea713c 754 Gene3D G3DSA:3.30.1370.120 454 530 1.6E-17 T 12-10-2018 IPR038591 NolW-like superfamily TSC_c04310 55bb529ba118db98354f9ddd1d5e67da 119 Gene3D G3DSA:3.10.129.10 1 119 2.2E-35 T 12-10-2018 TSC_c04310 55bb529ba118db98354f9ddd1d5e67da 119 Pfam PF03061 Thioesterase superfamily 18 88 1.5E-18 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TSC_c04310 55bb529ba118db98354f9ddd1d5e67da 119 SUPERFAMILY SSF54637 3 118 2.08E-34 T 12-10-2018 IPR029069 HotDog domain superfamily TSC_c00250 b0c7a41778cfd9006133a4b4b41e15da 615 SUPERFAMILY SSF52922 480 605 6.54E-27 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSC_c00250 b0c7a41778cfd9006133a4b4b41e15da 615 Gene3D G3DSA:3.40.50.970 306 483 2.8E-67 T 12-10-2018 TSC_c00250 b0c7a41778cfd9006133a4b4b41e15da 615 ProSitePatterns PS00802 Transketolase signature 2. 415 431 - T 12-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TSC_c00250 b0c7a41778cfd9006133a4b4b41e15da 615 Gene3D G3DSA:3.40.50.920 484 612 1.1E-42 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSC_c00250 b0c7a41778cfd9006133a4b4b41e15da 615 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 2 608 41.832 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TSC_c00250 b0c7a41778cfd9006133a4b4b41e15da 615 SUPERFAMILY SSF52518 3 371 1.1E-69 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c00250 b0c7a41778cfd9006133a4b4b41e15da 615 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 5 603 8.8E-219 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TSC_c00250 b0c7a41778cfd9006133a4b4b41e15da 615 Pfam PF02780 Transketolase, C-terminal domain 484 599 4.2E-25 T 12-10-2018 IPR033248 Transketolase, C-terminal domain TSC_c00250 b0c7a41778cfd9006133a4b4b41e15da 615 SUPERFAMILY SSF52518 307 493 5.68E-54 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c00250 b0c7a41778cfd9006133a4b4b41e15da 615 Pfam PF02779 Transketolase, pyrimidine binding domain 309 471 3.5E-41 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSC_c00250 b0c7a41778cfd9006133a4b4b41e15da 615 SMART SM00861 309 473 2.4E-62 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSC_c00250 b0c7a41778cfd9006133a4b4b41e15da 615 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 3 275 8.5E-113 T 12-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TSC_c05280 5ee0d78b446dce437c9ebcd22d6c5739 372 Gene3D G3DSA:3.40.50.2000 6 349 3.0E-136 T 12-10-2018 TSC_c05280 5ee0d78b446dce437c9ebcd22d6c5739 372 Gene3D G3DSA:3.40.50.2000 188 344 3.0E-136 T 12-10-2018 TSC_c05280 5ee0d78b446dce437c9ebcd22d6c5739 372 SUPERFAMILY SSF53756 1 365 4.08E-117 T 12-10-2018 TSC_c05280 5ee0d78b446dce437c9ebcd22d6c5739 372 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 3 355 4.1E-116 T 12-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 TSC_c05280 5ee0d78b446dce437c9ebcd22d6c5739 372 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 23 355 7.9E-100 T 12-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TSC_c05580 56fb11d9064728546cfb2aa1df0c208d 708 Gene3D G3DSA:3.40.50.300 288 624 3.3E-112 T 12-10-2018 TSC_c05580 56fb11d9064728546cfb2aa1df0c208d 708 Gene3D G3DSA:1.10.10.160 117 197 2.5E-101 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily TSC_c05580 56fb11d9064728546cfb2aa1df0c208d 708 SUPERFAMILY SSF52540 11 633 1.08E-167 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c05580 56fb11d9064728546cfb2aa1df0c208d 708 Gene3D G3DSA:3.40.50.300 17 280 2.5E-101 T 12-10-2018 TSC_c05580 56fb11d9064728546cfb2aa1df0c208d 708 Pfam PF13361 UvrD-like helicase C-terminal domain 500 607 2.1E-30 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TSC_c05580 56fb11d9064728546cfb2aa1df0c208d 708 Gene3D G3DSA:1.10.486.10 387 537 3.3E-112 T 12-10-2018 TSC_c05580 56fb11d9064728546cfb2aa1df0c208d 708 Pfam PF00580 UvrD/REP helicase N-terminal domain 17 134 1.4E-34 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 TSC_c05580 56fb11d9064728546cfb2aa1df0c208d 708 Pfam PF00580 UvrD/REP helicase N-terminal domain 141 279 1.3E-37 T 12-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 TSC_c05580 56fb11d9064728546cfb2aa1df0c208d 708 Pfam PF13361 UvrD-like helicase C-terminal domain 285 443 1.6E-33 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TSC_c05870 b2bd6450521370e9ff87b3e4fbffda47 322 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 230 319 2.4E-40 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TSC_c05870 b2bd6450521370e9ff87b3e4fbffda47 322 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 2 319 4.9E-114 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TSC_c05870 b2bd6450521370e9ff87b3e4fbffda47 322 Gene3D G3DSA:3.40.47.10 172 322 1.4E-58 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c05870 b2bd6450521370e9ff87b3e4fbffda47 322 Gene3D G3DSA:3.40.47.10 1 171 1.0E-69 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c05870 b2bd6450521370e9ff87b3e4fbffda47 322 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 104 182 2.1E-26 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TSC_c05870 b2bd6450521370e9ff87b3e4fbffda47 322 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 319 64.488 T 12-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TSC_c05870 b2bd6450521370e9ff87b3e4fbffda47 322 SUPERFAMILY SSF53901 3 319 8.02E-71 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c11700 2583c40af724db8a87e788b07c23378e 187 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 16 187 3.0E-61 T 12-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TSC_c11700 2583c40af724db8a87e788b07c23378e 187 PIRSF PIRSF015617 2 187 5.4E-64 T 12-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TSC_c11700 2583c40af724db8a87e788b07c23378e 187 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 18 186 4.0E-62 T 12-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 TSC_c11700 2583c40af724db8a87e788b07c23378e 187 Gene3D G3DSA:3.40.50.300 3 187 6.0E-65 T 12-10-2018 TSC_c11700 2583c40af724db8a87e788b07c23378e 187 SUPERFAMILY SSF52540 14 186 3.68E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c00750 75089d13eed87fe942d127b8edb97b8f 304 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 50 197 1.1E-28 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSC_c00750 75089d13eed87fe942d127b8edb97b8f 304 SUPERFAMILY SSF52518 14 276 5.9E-77 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c00750 75089d13eed87fe942d127b8edb97b8f 304 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 16 300 6.5E-134 T 12-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate TSC_c00750 75089d13eed87fe942d127b8edb97b8f 304 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 201 276 7.5E-23 T 12-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal TSC_c00750 75089d13eed87fe942d127b8edb97b8f 304 Gene3D G3DSA:3.40.50.970 25 201 8.4E-22 T 12-10-2018 TSC_c19820 c73e6015c96c460e06120bee076bada9 109 SUPERFAMILY SSF50249 5 108 7.35E-31 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c19820 c73e6015c96c460e06120bee076bada9 109 Gene3D G3DSA:2.40.50.140 3 109 5.9E-30 T 12-10-2018 TSC_c19820 c73e6015c96c460e06120bee076bada9 109 Pfam PF01588 Putative tRNA binding domain 12 107 2.4E-16 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TSC_c19820 c73e6015c96c460e06120bee076bada9 109 TIGRFAM TIGR02222 chap_CsaA: export-related chaperone protein CsaA 5 108 3.3E-47 T 12-10-2018 IPR008231 Probable chaperone CsaA TSC_c05300 f1e9e43d2dbd1f9bb9f26c8e19493c0c 208 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 208 1.9E-86 T 12-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TSC_c05300 f1e9e43d2dbd1f9bb9f26c8e19493c0c 208 Gene3D G3DSA:3.40.50.2020 1 208 2.1E-80 T 12-10-2018 TSC_c05300 f1e9e43d2dbd1f9bb9f26c8e19493c0c 208 SUPERFAMILY SSF53271 3 206 8.11E-69 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TSC_c05300 f1e9e43d2dbd1f9bb9f26c8e19493c0c 208 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 208 45.763 T 12-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TSC_c05300 f1e9e43d2dbd1f9bb9f26c8e19493c0c 208 Pfam PF14681 Uracil phosphoribosyltransferase 6 207 3.4E-73 T 12-10-2018 TSC_c06610 6f7e6dc7f5330edb393456b44e3a7807 220 PIRSF PIRSF003107 1 217 2.4E-65 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 TSC_c06610 6f7e6dc7f5330edb393456b44e3a7807 220 Gene3D G3DSA:1.20.58.220 1 215 1.8E-70 T 12-10-2018 IPR038078 PhoU-like domain superfamily TSC_c06610 6f7e6dc7f5330edb393456b44e3a7807 220 Pfam PF01895 PhoU domain 17 103 1.1E-21 T 12-10-2018 IPR026022 PhoU domain TSC_c06610 6f7e6dc7f5330edb393456b44e3a7807 220 Pfam PF01895 PhoU domain 119 204 7.9E-20 T 12-10-2018 IPR026022 PhoU domain TSC_c06610 6f7e6dc7f5330edb393456b44e3a7807 220 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 5 212 5.1E-65 T 12-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 TSC_c06610 6f7e6dc7f5330edb393456b44e3a7807 220 SUPERFAMILY SSF109755 2 214 7.22E-68 T 12-10-2018 TSC_c07280 87d638365ef08af42d179854cace27cb 344 Gene3D G3DSA:3.40.50.2300 68 314 6.2E-73 T 12-10-2018 TSC_c07280 87d638365ef08af42d179854cace27cb 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 12-10-2018 TSC_c07280 87d638365ef08af42d179854cace27cb 344 Gene3D G3DSA:1.10.260.40 1 62 4.3E-23 T 12-10-2018 TSC_c07280 87d638365ef08af42d179854cace27cb 344 SMART SM00354 5 75 2.0E-25 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSC_c07280 87d638365ef08af42d179854cace27cb 344 Pfam PF13377 Periplasmic binding protein-like domain 194 334 9.5E-25 T 12-10-2018 TSC_c07280 87d638365ef08af42d179854cace27cb 344 SUPERFAMILY SSF47413 4 63 1.46E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSC_c07280 87d638365ef08af42d179854cace27cb 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 52 7.0E-19 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSC_c07280 87d638365ef08af42d179854cace27cb 344 SUPERFAMILY SSF53822 65 337 2.78E-43 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TSC_c07280 87d638365ef08af42d179854cace27cb 344 Gene3D G3DSA:3.40.50.2300 161 294 6.2E-73 T 12-10-2018 TSC_c13810 abcb13b0bef2a0ac9b9258d339f295b3 349 Gene3D G3DSA:3.30.420.10 181 347 5.7E-14 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSC_c13810 abcb13b0bef2a0ac9b9258d339f295b3 349 Pfam PF13565 Homeodomain-like domain 63 138 1.5E-8 T 12-10-2018 TSC_c13810 abcb13b0bef2a0ac9b9258d339f295b3 349 SUPERFAMILY SSF53098 182 338 1.05E-26 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c13810 abcb13b0bef2a0ac9b9258d339f295b3 349 SUPERFAMILY SSF46689 43 140 2.15E-9 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSC_c13810 abcb13b0bef2a0ac9b9258d339f295b3 349 Pfam PF13683 Integrase core domain 266 331 1.9E-18 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 TSC_c01420 446887186ae297b4d8b1db42f4a35040 605 Gene3D G3DSA:1.10.4030.30 76 291 7.0E-30 T 12-10-2018 TSC_c01420 446887186ae297b4d8b1db42f4a35040 605 SUPERFAMILY SSF109998 332 464 8.63E-10 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily TSC_c01420 446887186ae297b4d8b1db42f4a35040 605 SUPERFAMILY SSF54534 172 276 6.48E-13 T 12-10-2018 TSC_c01420 446887186ae297b4d8b1db42f4a35040 605 Pfam PF13145 PPIC-type PPIASE domain 160 290 1.4E-18 T 12-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 TSC_c01420 446887186ae297b4d8b1db42f4a35040 605 Pfam PF13145 PPIC-type PPIASE domain 419 541 1.3E-14 T 12-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 TSC_c01420 446887186ae297b4d8b1db42f4a35040 605 Gene3D G3DSA:3.10.50.40 180 278 7.0E-30 T 12-10-2018 TSC_c01420 446887186ae297b4d8b1db42f4a35040 605 Pfam PF13624 SurA N-terminal domain 8 149 4.6E-10 T 12-10-2018 TSC_c01420 446887186ae297b4d8b1db42f4a35040 605 SUPERFAMILY SSF109998 39 209 4.32E-19 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily TSC_c13070 a9810698b391223c2ade7ac660cdf581 223 Pfam PF03167 Uracil DNA glycosylase superfamily 48 214 1.1E-32 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSC_c13070 a9810698b391223c2ade7ac660cdf581 223 SUPERFAMILY SSF52141 16 219 1.31E-47 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSC_c13070 a9810698b391223c2ade7ac660cdf581 223 SMART SM00986 48 214 6.7E-29 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSC_c13070 a9810698b391223c2ade7ac660cdf581 223 SMART SM00987 48 214 6.7E-29 T 12-10-2018 TSC_c13070 a9810698b391223c2ade7ac660cdf581 223 Gene3D G3DSA:3.40.470.10 5 223 1.8E-72 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSC_c03790 e7cbbdf35dab77b71ddf6223ff4f9af9 206 Gene3D G3DSA:3.40.50.150 17 199 1.7E-30 T 12-10-2018 TSC_c03790 e7cbbdf35dab77b71ddf6223ff4f9af9 206 SUPERFAMILY SSF53335 8 191 1.66E-32 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c03790 e7cbbdf35dab77b71ddf6223ff4f9af9 206 Pfam PF08241 Methyltransferase domain 41 135 1.0E-18 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSC_c18210 08c4713d6c9c483004daa8461f2edccd 399 SUPERFAMILY SSF47203 246 395 1.3E-39 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSC_c18210 08c4713d6c9c483004daa8461f2edccd 399 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 26 138 1.1E-35 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSC_c18210 08c4713d6c9c483004daa8461f2edccd 399 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 352 371 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSC_c18210 08c4713d6c9c483004daa8461f2edccd 399 Gene3D G3DSA:1.20.140.10 251 399 4.0E-39 T 12-10-2018 TSC_c18210 08c4713d6c9c483004daa8461f2edccd 399 Gene3D G3DSA:1.10.540.10 15 139 6.4E-42 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSC_c18210 08c4713d6c9c483004daa8461f2edccd 399 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 246 392 6.4E-30 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSC_c18210 08c4713d6c9c483004daa8461f2edccd 399 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 142 234 2.0E-23 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSC_c18210 08c4713d6c9c483004daa8461f2edccd 399 Gene3D G3DSA:2.40.110.10 141 245 7.2E-34 T 12-10-2018 TSC_c18210 08c4713d6c9c483004daa8461f2edccd 399 SUPERFAMILY SSF56645 16 245 1.15E-75 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSC_c18210 08c4713d6c9c483004daa8461f2edccd 399 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 144 156 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 SUPERFAMILY SSF52540 8 273 2.52E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 Gene3D G3DSA:2.40.30.10 280 376 4.1E-20 T 12-10-2018 TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 Gene3D G3DSA:3.30.70.240 573 643 1.3E-78 T 12-10-2018 TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 Pfam PF00009 Elongation factor Tu GTP binding domain 7 273 1.7E-33 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 Gene3D G3DSA:3.30.70.870 377 452 8.8E-24 T 12-10-2018 TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 SMART SM00889 452 567 3.9E-61 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 SUPERFAMILY SSF54980 569 660 1.34E-23 T 12-10-2018 IPR035647 EF-G domain III/V-like TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 SUPERFAMILY SSF54211 454 568 1.52E-40 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 146 2.2E-12 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 Pfam PF03764 Elongation factor G, domain IV 451 566 1.4E-37 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 SUPERFAMILY SSF50447 256 370 2.14E-19 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 SMART SM00838 569 656 3.8E-33 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 Pfam PF00679 Elongation factor G C-terminus 569 655 7.7E-25 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 Gene3D G3DSA:3.30.230.10 456 656 1.3E-78 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 Pfam PF14492 Elongation Factor G, domain II 377 448 5.5E-24 T 12-10-2018 TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 SUPERFAMILY SSF54980 378 453 1.19E-19 T 12-10-2018 IPR035647 EF-G domain III/V-like TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 Pfam PF03144 Elongation factor Tu domain 2 297 361 2.8E-7 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TSC_c21580 b3217f9b85c1a4373951a37feeb489d1 666 Gene3D G3DSA:3.40.50.300 4 279 3.7E-76 T 12-10-2018 TSC_c16810 37883d104fec8ea58bd2ad71b9bf64cf 440 SUPERFAMILY SSF53850 28 427 2.43E-76 T 12-10-2018 TSC_c16810 37883d104fec8ea58bd2ad71b9bf64cf 440 Gene3D G3DSA:3.40.190.10 145 424 2.7E-112 T 12-10-2018 TSC_c16810 37883d104fec8ea58bd2ad71b9bf64cf 440 Pfam PF13416 Bacterial extracellular solute-binding protein 46 364 4.3E-47 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSC_c16810 37883d104fec8ea58bd2ad71b9bf64cf 440 Gene3D G3DSA:3.40.190.10 32 385 2.7E-112 T 12-10-2018 TSC_c12460 92b7f0db19892c9b74e63228e863a372 205 SMART SM01101 1 205 1.8E-54 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 TSC_c12460 92b7f0db19892c9b74e63228e863a372 205 Pfam PF08798 CRISPR associated protein 1 205 1.5E-51 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 TSC_c12460 92b7f0db19892c9b74e63228e863a372 205 SUPERFAMILY SSF117987 89 205 8.89E-28 T 12-10-2018 TSC_c12460 92b7f0db19892c9b74e63228e863a372 205 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 1 205 5.3E-24 T 12-10-2018 IPR010179 CRISPR-associated protein Cse3 TSC_c12460 92b7f0db19892c9b74e63228e863a372 205 Gene3D G3DSA:3.30.70.1210 88 205 3.1E-30 T 12-10-2018 TSC_c12460 92b7f0db19892c9b74e63228e863a372 205 Gene3D G3DSA:3.30.70.1200 1 87 5.1E-28 T 12-10-2018 TSC_c12460 92b7f0db19892c9b74e63228e863a372 205 SUPERFAMILY SSF117987 1 81 9.15E-22 T 12-10-2018 TSC_c00380 87ddff1de75d7ac946557ec56be94caa 482 SUPERFAMILY SSF48452 137 257 6.58E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c00380 87ddff1de75d7ac946557ec56be94caa 482 Gene3D G3DSA:1.25.40.10 9 101 3.0E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c00380 87ddff1de75d7ac946557ec56be94caa 482 Gene3D G3DSA:1.25.40.10 102 246 2.1E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c00380 87ddff1de75d7ac946557ec56be94caa 482 SUPERFAMILY SSF48452 18 163 1.3E-10 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c00380 87ddff1de75d7ac946557ec56be94caa 482 Pfam PF13432 Tetratricopeptide repeat 121 160 0.0011 T 12-10-2018 TSC_c11860 911a255d4b7aefbe49f12de7aae7c645 252 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 19 250 9.3E-56 T 12-10-2018 TSC_c11860 911a255d4b7aefbe49f12de7aae7c645 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 5.1E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c11860 911a255d4b7aefbe49f12de7aae7c645 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 5.1E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c11860 911a255d4b7aefbe49f12de7aae7c645 252 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 5.1E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c11860 911a255d4b7aefbe49f12de7aae7c645 252 SUPERFAMILY SSF51735 9 251 8.34E-77 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c11860 911a255d4b7aefbe49f12de7aae7c645 252 Gene3D G3DSA:3.40.50.720 1 251 9.5E-78 T 12-10-2018 TSC_c11860 911a255d4b7aefbe49f12de7aae7c645 252 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 185 0.0055 T 12-10-2018 TSC_c11860 911a255d4b7aefbe49f12de7aae7c645 252 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSC_c11860 911a255d4b7aefbe49f12de7aae7c645 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 1.8E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c11860 911a255d4b7aefbe49f12de7aae7c645 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.8E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c11860 911a255d4b7aefbe49f12de7aae7c645 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.8E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c11860 911a255d4b7aefbe49f12de7aae7c645 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.8E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c11860 911a255d4b7aefbe49f12de7aae7c645 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 1.8E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c11860 911a255d4b7aefbe49f12de7aae7c645 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.8E-41 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c15330 54ad23ecd57f3781368a512a80ff29a2 348 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 342 40.637 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSC_c15330 54ad23ecd57f3781368a512a80ff29a2 348 Gene3D G3DSA:3.30.360.10 143 316 3.5E-115 T 12-10-2018 TSC_c15330 54ad23ecd57f3781368a512a80ff29a2 348 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 140 156 - T 12-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSC_c15330 54ad23ecd57f3781368a512a80ff29a2 348 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 3 135 3.1E-31 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSC_c15330 54ad23ecd57f3781368a512a80ff29a2 348 Gene3D G3DSA:3.40.50.720 3 333 3.5E-115 T 12-10-2018 TSC_c15330 54ad23ecd57f3781368a512a80ff29a2 348 SMART SM00859 3 137 8.3E-49 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSC_c15330 54ad23ecd57f3781368a512a80ff29a2 348 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 2 348 1.0E-119 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSC_c15330 54ad23ecd57f3781368a512a80ff29a2 348 SUPERFAMILY SSF55347 145 316 7.2E-39 T 12-10-2018 TSC_c15330 54ad23ecd57f3781368a512a80ff29a2 348 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 154 319 2.1E-16 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSC_c15330 54ad23ecd57f3781368a512a80ff29a2 348 SUPERFAMILY SSF51735 2 159 2.89E-47 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c21390 3e990b363ffea8cae099909aa52b1770 242 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 5 229 4.8E-51 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TSC_c21390 3e990b363ffea8cae099909aa52b1770 242 Gene3D G3DSA:3.40.1390.30 97 213 9.1E-86 T 12-10-2018 TSC_c21390 3e990b363ffea8cae099909aa52b1770 242 Gene3D G3DSA:3.40.1390.30 6 230 9.1E-86 T 12-10-2018 TSC_c21390 3e990b363ffea8cae099909aa52b1770 242 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 2 240 2.0E-48 T 12-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 TSC_c21390 3e990b363ffea8cae099909aa52b1770 242 SUPERFAMILY SSF102705 1 241 4.71E-63 T 12-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily TSC_c02600 dc67b603957f01aa5b9c7d696fc151e2 429 Gene3D G3DSA:2.40.420.20 342 406 2.4E-12 T 12-10-2018 TSC_c02600 dc67b603957f01aa5b9c7d696fc151e2 429 Gene3D G3DSA:2.40.50.100 57 121 1.9E-9 T 12-10-2018 TSC_c02600 dc67b603957f01aa5b9c7d696fc151e2 429 SUPERFAMILY SSF111369 50 162 1.44E-16 T 12-10-2018 TSC_c02600 dc67b603957f01aa5b9c7d696fc151e2 429 Gene3D G3DSA:2.40.30.170 260 341 3.1E-16 T 12-10-2018 TSC_c02600 dc67b603957f01aa5b9c7d696fc151e2 429 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 203 403 1.7E-40 T 12-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 TSC_c02600 dc67b603957f01aa5b9c7d696fc151e2 429 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 166 336 4.3E-18 T 12-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain TSC_c02600 dc67b603957f01aa5b9c7d696fc151e2 429 Gene3D G3DSA:2.40.50.100 213 259 9.6E-10 T 12-10-2018 TSC_c02600 dc67b603957f01aa5b9c7d696fc151e2 429 Gene3D G3DSA:1.10.287.470 122 204 5.2E-7 T 12-10-2018 TSC_c02600 dc67b603957f01aa5b9c7d696fc151e2 429 SUPERFAMILY SSF111369 171 315 6.41E-12 T 12-10-2018 TSC_c17400 5fbe47d131402a650444b70d738f8f83 103 SUPERFAMILY SSF117916 6 102 2.58E-31 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSC_c17400 5fbe47d131402a650444b70d738f8f83 103 Gene3D G3DSA:3.30.300.130 1 103 4.6E-37 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSC_c17400 5fbe47d131402a650444b70d738f8f83 103 Pfam PF01883 Iron-sulfur cluster assembly protein 9 80 3.6E-23 T 12-10-2018 IPR002744 MIP18 family-like TSC_c21830 55ba6c9a84c47ca492769fab4ebbb72a 735 Gene3D G3DSA:3.30.1330.10 371 551 2.3E-59 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSC_c21830 55ba6c9a84c47ca492769fab4ebbb72a 735 Gene3D G3DSA:3.90.650.10 554 733 3.2E-46 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSC_c21830 55ba6c9a84c47ca492769fab4ebbb72a 735 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 735 279.169 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSC_c21830 55ba6c9a84c47ca492769fab4ebbb72a 735 PIRSF PIRSF001587 1 734 4.0E-298 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSC_c21830 55ba6c9a84c47ca492769fab4ebbb72a 735 SUPERFAMILY SSF55326 7 187 4.19E-52 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSC_c21830 55ba6c9a84c47ca492769fab4ebbb72a 735 Gene3D G3DSA:3.90.650.10 15 363 2.4E-144 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSC_c21830 55ba6c9a84c47ca492769fab4ebbb72a 735 Gene3D G3DSA:3.30.1330.10 37 186 2.4E-144 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSC_c21830 55ba6c9a84c47ca492769fab4ebbb72a 735 SUPERFAMILY SSF55326 385 549 6.28E-44 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSC_c21830 55ba6c9a84c47ca492769fab4ebbb72a 735 SUPERFAMILY SSF56042 192 415 5.38E-49 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSC_c21830 55ba6c9a84c47ca492769fab4ebbb72a 735 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 13 730 1.1E-268 T 12-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSC_c21830 55ba6c9a84c47ca492769fab4ebbb72a 735 Pfam PF02769 AIR synthase related protein, C-terminal domain 205 343 2.7E-29 T 12-10-2018 IPR010918 PurM-like, C-terminal domain TSC_c21830 55ba6c9a84c47ca492769fab4ebbb72a 735 Pfam PF02769 AIR synthase related protein, C-terminal domain 560 700 1.4E-17 T 12-10-2018 IPR010918 PurM-like, C-terminal domain TSC_c21830 55ba6c9a84c47ca492769fab4ebbb72a 735 SUPERFAMILY SSF56042 557 731 1.57E-37 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSC_c21830 55ba6c9a84c47ca492769fab4ebbb72a 735 Pfam PF00586 AIR synthase related protein, N-terminal domain 80 181 7.0E-25 T 12-10-2018 IPR016188 PurM-like, N-terminal domain TSC_c21830 55ba6c9a84c47ca492769fab4ebbb72a 735 Pfam PF00586 AIR synthase related protein, N-terminal domain 431 547 2.0E-19 T 12-10-2018 IPR016188 PurM-like, N-terminal domain TSC_c12980 7c0bf5bc15d1290837f57d053951675e 679 Gene3D G3DSA:2.40.40.20 557 678 5.7E-43 T 12-10-2018 TSC_c12980 7c0bf5bc15d1290837f57d053951675e 679 SUPERFAMILY SSF50692 530 677 1.38E-48 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSC_c12980 7c0bf5bc15d1290837f57d053951675e 679 Gene3D G3DSA:3.40.50.740 59 524 5.5E-180 T 12-10-2018 TSC_c12980 7c0bf5bc15d1290837f57d053951675e 679 Pfam PF01568 Molydopterin dinucleotide binding domain 567 671 1.8E-29 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSC_c12980 7c0bf5bc15d1290837f57d053951675e 679 Pfam PF00384 Molybdopterin oxidoreductase 54 477 1.2E-90 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c12980 7c0bf5bc15d1290837f57d053951675e 679 TIGRFAM TIGR01591 Fdh-alpha: formate dehydrogenase, alpha subunit 3 674 3.2E-238 T 12-10-2018 IPR006478 Formate dehydrogenase, alpha subunit GO:0008863|GO:0015942|GO:0055114 KEGG: 00630+1.17.1.9|KEGG: 00680+1.17.1.9|MetaCyc: PWY-1881|MetaCyc: PWY-5497|MetaCyc: PWY-6696|MetaCyc: PWY-7985 TSC_c12980 7c0bf5bc15d1290837f57d053951675e 679 SUPERFAMILY SSF53706 2 569 4.32E-195 T 12-10-2018 TSC_c12980 7c0bf5bc15d1290837f57d053951675e 679 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 605 632 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 TSC_c12980 7c0bf5bc15d1290837f57d053951675e 679 Gene3D G3DSA:3.40.228.10 134 332 5.5E-180 T 12-10-2018 TSC_c12980 7c0bf5bc15d1290837f57d053951675e 679 SMART SM00926 1 51 1.7E-13 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c12980 7c0bf5bc15d1290837f57d053951675e 679 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 2 48 3.3E-12 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c12980 7c0bf5bc15d1290837f57d053951675e 679 Gene3D G3DSA:2.20.25.90 1 50 4.6E-18 T 12-10-2018 TSC_c11960 156bef2cb33b4d5255c34f56cb600e8c 193 Gene3D G3DSA:1.10.490.10 11 163 9.7E-22 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TSC_c11960 156bef2cb33b4d5255c34f56cb600e8c 193 Pfam PF11563 Protoglobin 20 158 1.3E-15 T 12-10-2018 TSC_c11960 156bef2cb33b4d5255c34f56cb600e8c 193 SUPERFAMILY SSF46458 14 117 6.48E-12 T 12-10-2018 IPR009050 Globin-like superfamily TSC_c03860 042d0ba747459fff7169f93308bfb771 164 SUPERFAMILY SSF55008 71 138 7.72E-23 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TSC_c03860 042d0ba747459fff7169f93308bfb771 164 Gene3D G3DSA:3.30.70.100 5 69 6.0E-19 T 12-10-2018 TSC_c03860 042d0ba747459fff7169f93308bfb771 164 Gene3D G3DSA:3.30.70.100 70 136 5.4E-23 T 12-10-2018 TSC_c03860 042d0ba747459fff7169f93308bfb771 164 Pfam PF00403 Heavy-metal-associated domain 74 134 1.3E-17 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TSC_c03860 042d0ba747459fff7169f93308bfb771 164 Pfam PF00403 Heavy-metal-associated domain 9 66 3.8E-12 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TSC_c03860 042d0ba747459fff7169f93308bfb771 164 ProSitePatterns PS01047 Heavy-metal-associated domain. 9 38 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 TSC_c03860 042d0ba747459fff7169f93308bfb771 164 SUPERFAMILY SSF55008 5 70 1.23E-18 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TSC_c03860 042d0ba747459fff7169f93308bfb771 164 ProSitePatterns PS01047 Heavy-metal-associated domain. 76 105 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 TSC_c03860 042d0ba747459fff7169f93308bfb771 164 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 72 134 9.4E-15 T 12-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 TSC_c03860 042d0ba747459fff7169f93308bfb771 164 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 6 66 4.5E-9 T 12-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 TSC_c07730 a0d63b6837b796435fa896fea4fb741f 156 SUPERFAMILY SSF54523 6 110 3.92E-12 T 12-10-2018 TSC_c07730 a0d63b6837b796435fa896fea4fb741f 156 Gene3D G3DSA:3.30.700.10 6 154 4.4E-6 T 12-10-2018 TSC_c07730 a0d63b6837b796435fa896fea4fb741f 156 Pfam PF12019 Type II transport protein GspH 39 151 2.0E-12 T 12-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 TSC_c07730 a0d63b6837b796435fa896fea4fb741f 156 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 24 3.2E-5 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site TSC_c07730 a0d63b6837b796435fa896fea4fb741f 156 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 26 1.8E-5 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site TSC_c07160 58b8d61dec80054868d81dbf698d66ed 150 SUPERFAMILY SSF88697 1 147 8.2E-56 T 12-10-2018 IPR015947 PUA-like superfamily TSC_c07160 58b8d61dec80054868d81dbf698d66ed 150 Gene3D G3DSA:3.10.590.10 1 148 4.7E-51 T 12-10-2018 TSC_c07160 58b8d61dec80054868d81dbf698d66ed 150 Pfam PF01878 EVE domain 2 144 1.1E-46 T 12-10-2018 IPR002740 EVE domain TSC_c00810 31f4e8f10d7d25417fa5c1b7a35336b6 542 Gene3D G3DSA:3.50.7.10 190 370 1.6E-235 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily TSC_c00810 31f4e8f10d7d25417fa5c1b7a35336b6 542 PRINTS PR00298 60kDa chaperonin signature 26 52 1.6E-72 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSC_c00810 31f4e8f10d7d25417fa5c1b7a35336b6 542 PRINTS PR00298 60kDa chaperonin signature 396 417 1.6E-72 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSC_c00810 31f4e8f10d7d25417fa5c1b7a35336b6 542 PRINTS PR00298 60kDa chaperonin signature 82 109 1.6E-72 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSC_c00810 31f4e8f10d7d25417fa5c1b7a35336b6 542 PRINTS PR00298 60kDa chaperonin signature 266 289 1.6E-72 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSC_c00810 31f4e8f10d7d25417fa5c1b7a35336b6 542 PRINTS PR00298 60kDa chaperonin signature 348 373 1.6E-72 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSC_c00810 31f4e8f10d7d25417fa5c1b7a35336b6 542 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 525 6.1E-105 T 12-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 TSC_c00810 31f4e8f10d7d25417fa5c1b7a35336b6 542 Gene3D G3DSA:1.10.560.10 7 522 1.6E-235 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily TSC_c00810 31f4e8f10d7d25417fa5c1b7a35336b6 542 Gene3D G3DSA:3.30.260.10 135 408 1.6E-235 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TSC_c00810 31f4e8f10d7d25417fa5c1b7a35336b6 542 SUPERFAMILY SSF54849 136 201 2.52E-23 T 12-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily TSC_c00810 31f4e8f10d7d25417fa5c1b7a35336b6 542 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 528 6.4E-257 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSC_c00810 31f4e8f10d7d25417fa5c1b7a35336b6 542 Hamap MF_00600 60 kDa chaperonin [groL]. 1 540 42.106 T 12-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSC_c00810 31f4e8f10d7d25417fa5c1b7a35336b6 542 SUPERFAMILY SSF48592 6 522 1.91E-82 T 12-10-2018 IPR027413 GroEL-like equatorial domain superfamily TSC_c00810 31f4e8f10d7d25417fa5c1b7a35336b6 542 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 12-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 TSC_c00810 31f4e8f10d7d25417fa5c1b7a35336b6 542 SUPERFAMILY SSF52029 182 374 7.78E-83 T 12-10-2018 IPR027409 GroEL-like apical domain superfamily TSC_c06490 06b43d2ed06cd7aa38aed97fa74fc5a3 238 Pfam PF00106 short chain dehydrogenase 15 137 4.7E-20 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c06490 06b43d2ed06cd7aa38aed97fa74fc5a3 238 Gene3D G3DSA:3.40.50.720 5 221 7.8E-26 T 12-10-2018 TSC_c06490 06b43d2ed06cd7aa38aed97fa74fc5a3 238 SUPERFAMILY SSF51735 10 185 5.94E-28 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c06490 06b43d2ed06cd7aa38aed97fa74fc5a3 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.3E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c06490 06b43d2ed06cd7aa38aed97fa74fc5a3 238 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 1.3E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 SUPERFAMILY SSF52374 2 345 2.95E-111 T 12-10-2018 TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 Gene3D G3DSA:3.40.50.620 5 330 5.0E-148 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 3 134 1.4E-11 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 510 626 2.4E-40 T 12-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 SUPERFAMILY SSF50249 526 624 2.94E-35 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 SUPERFAMILY SSF47323 349 499 6.54E-33 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 Pfam PF09334 tRNA synthetases class I (M) 137 360 2.0E-52 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 Gene3D G3DSA:1.10.730.10 337 500 2.3E-43 T 12-10-2018 TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 Gene3D G3DSA:2.170.220.10 116 226 5.0E-148 T 12-10-2018 TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 PRINTS PR01041 Methionyl-tRNA synthetase signature 255 270 2.0E-33 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 PRINTS PR01041 Methionyl-tRNA synthetase signature 224 235 2.0E-33 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 PRINTS PR01041 Methionyl-tRNA synthetase signature 39 53 2.0E-33 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 PRINTS PR01041 Methionyl-tRNA synthetase signature 87 98 2.0E-33 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 2.0E-33 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 PRINTS PR01041 Methionyl-tRNA synthetase signature 348 359 2.0E-33 T 12-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 Hamap MF_01228 Methionine--tRNA ligase [metG]. 1 500 46.052 T 12-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 Gene3D G3DSA:2.40.50.140 521 627 3.1E-38 T 12-10-2018 TSC_c17870 93188717c09a5b5b235f7f1213e75dad 627 Pfam PF01588 Putative tRNA binding domain 533 624 1.4E-30 T 12-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 TSC_c07850 781fb244a6996d8abad51c4aa5c2b893 343 SUPERFAMILY SSF50129 1 174 4.87E-56 T 12-10-2018 IPR011032 GroES-like superfamily TSC_c07850 781fb244a6996d8abad51c4aa5c2b893 343 Pfam PF00107 Zinc-binding dehydrogenase 175 295 1.7E-15 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSC_c07850 781fb244a6996d8abad51c4aa5c2b893 343 SUPERFAMILY SSF51735 142 305 3.09E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c07850 781fb244a6996d8abad51c4aa5c2b893 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 132 4.4E-35 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSC_c07850 781fb244a6996d8abad51c4aa5c2b893 343 Gene3D G3DSA:3.90.180.10 17 333 8.4E-131 T 12-10-2018 TSC_c07850 781fb244a6996d8abad51c4aa5c2b893 343 Gene3D G3DSA:3.40.50.720 153 286 8.4E-131 T 12-10-2018 TSC_c07850 781fb244a6996d8abad51c4aa5c2b893 343 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TSC_c07850 781fb244a6996d8abad51c4aa5c2b893 343 SMART SM00829 8 339 3.6E-6 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSC_c20520 f3e078ceb5ba4e6cac7c6367958c4b93 189 Gene3D G3DSA:3.40.50.10420 29 185 7.6E-28 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily TSC_c20520 f3e078ceb5ba4e6cac7c6367958c4b93 189 Pfam PF02589 LUD domain 92 182 1.7E-14 T 12-10-2018 IPR003741 LUD domain TSC_c20520 f3e078ceb5ba4e6cac7c6367958c4b93 189 SUPERFAMILY SSF100950 33 185 1.26E-25 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TSC_c07970 932d62a04b2ca930d60b36576e215c0d 504 Gene3D G3DSA:3.40.720.10 38 443 6.1E-95 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TSC_c07970 932d62a04b2ca930d60b36576e215c0d 504 Pfam PF00245 Alkaline phosphatase 37 469 9.0E-70 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TSC_c07970 932d62a04b2ca930d60b36576e215c0d 504 SMART SM00098 38 471 2.4E-44 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TSC_c07970 932d62a04b2ca930d60b36576e215c0d 504 PRINTS PR00113 Alkaline phosphatase signature 129 149 1.4E-35 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TSC_c07970 932d62a04b2ca930d60b36576e215c0d 504 PRINTS PR00113 Alkaline phosphatase signature 246 275 1.4E-35 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TSC_c07970 932d62a04b2ca930d60b36576e215c0d 504 PRINTS PR00113 Alkaline phosphatase signature 92 107 1.4E-35 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TSC_c07970 932d62a04b2ca930d60b36576e215c0d 504 PRINTS PR00113 Alkaline phosphatase signature 173 183 1.4E-35 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TSC_c07970 932d62a04b2ca930d60b36576e215c0d 504 PRINTS PR00113 Alkaline phosphatase signature 37 57 1.4E-35 T 12-10-2018 IPR001952 Alkaline phosphatase GO:0016791 KEGG: 00730+3.1.3.1|KEGG: 00790+3.1.3.1|MetaCyc: PWY-5083|MetaCyc: PWY-5491 TSC_c07970 932d62a04b2ca930d60b36576e215c0d 504 SUPERFAMILY SSF53649 28 474 6.21E-99 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TSC_c07970 932d62a04b2ca930d60b36576e215c0d 504 Gene3D G3DSA:1.10.1200.140 359 442 6.1E-95 T 12-10-2018 TSC_c08100 0a47448c3e20b739ddbbf3d3f67db173 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 164 176 3.7E-59 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSC_c08100 0a47448c3e20b739ddbbf3d3f67db173 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 185 202 3.7E-59 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSC_c08100 0a47448c3e20b739ddbbf3d3f67db173 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 441 460 3.7E-59 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSC_c08100 0a47448c3e20b739ddbbf3d3f67db173 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 217 234 3.7E-59 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSC_c08100 0a47448c3e20b739ddbbf3d3f67db173 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 3.7E-59 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSC_c08100 0a47448c3e20b739ddbbf3d3f67db173 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 234 244 3.7E-59 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSC_c08100 0a47448c3e20b739ddbbf3d3f67db173 506 PRINTS PR01043 Glycyl-tRNA synthetase signature 356 368 3.7E-59 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSC_c08100 0a47448c3e20b739ddbbf3d3f67db173 506 Pfam PF03129 Anticodon binding domain 401 503 2.0E-27 T 12-10-2018 IPR004154 Anticodon-binding TSC_c08100 0a47448c3e20b739ddbbf3d3f67db173 506 Gene3D G3DSA:3.40.50.800 394 505 1.1E-36 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily TSC_c08100 0a47448c3e20b739ddbbf3d3f67db173 506 SUPERFAMILY SSF52954 397 504 1.45E-28 T 12-10-2018 TSC_c08100 0a47448c3e20b739ddbbf3d3f67db173 506 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 3 505 49.442 T 12-10-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 TSC_c08100 0a47448c3e20b739ddbbf3d3f67db173 506 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 7 261 1.6E-78 T 12-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSC_c08100 0a47448c3e20b739ddbbf3d3f67db173 506 SUPERFAMILY SSF55681 6 404 1.37E-126 T 12-10-2018 TSC_c08100 0a47448c3e20b739ddbbf3d3f67db173 506 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 183 374 4.1E-11 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c22490 b666735460afe7aa917cced549dbd814 136 ProSitePatterns PS00055 Ribosomal protein S12 signature. 45 52 - T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22490 b666735460afe7aa917cced549dbd814 136 Gene3D G3DSA:2.40.50.140 1 134 4.1E-66 T 12-10-2018 TSC_c22490 b666735460afe7aa917cced549dbd814 136 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 4 125 2.5E-67 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22490 b666735460afe7aa917cced549dbd814 136 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 3 125 39.687 T 12-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22490 b666735460afe7aa917cced549dbd814 136 SUPERFAMILY SSF50249 4 126 8.31E-53 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c22490 b666735460afe7aa917cced549dbd814 136 PRINTS PR01034 Ribosomal protein S12 signature 44 59 1.8E-57 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22490 b666735460afe7aa917cced549dbd814 136 PRINTS PR01034 Ribosomal protein S12 signature 29 44 1.8E-57 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22490 b666735460afe7aa917cced549dbd814 136 PRINTS PR01034 Ribosomal protein S12 signature 112 124 1.8E-57 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22490 b666735460afe7aa917cced549dbd814 136 PRINTS PR01034 Ribosomal protein S12 signature 96 112 1.8E-57 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22490 b666735460afe7aa917cced549dbd814 136 PRINTS PR01034 Ribosomal protein S12 signature 79 96 1.8E-57 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22490 b666735460afe7aa917cced549dbd814 136 PRINTS PR01034 Ribosomal protein S12 signature 60 79 1.8E-57 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22490 b666735460afe7aa917cced549dbd814 136 Pfam PF00164 Ribosomal protein S12/S23 14 125 5.0E-43 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22490 b666735460afe7aa917cced549dbd814 136 PIRSF PIRSF002133 3 126 2.1E-55 T 12-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c10370 214bfbfafe744a0aa995e881b122b0db 398 Pfam PF02687 FtsX-like permease family 284 390 5.8E-6 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TSC_c08410 0bf4cc33c6ea8ed70266e412aa802da2 337 PIRSF PIRSF000116 202 333 1.4E-15 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TSC_c08410 0bf4cc33c6ea8ed70266e412aa802da2 337 PIRSF PIRSF000116 4 207 3.8E-46 T 12-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TSC_c08410 0bf4cc33c6ea8ed70266e412aa802da2 337 SUPERFAMILY SSF51735 1 182 1.79E-76 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c08410 0bf4cc33c6ea8ed70266e412aa802da2 337 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 6.9E-64 T 12-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TSC_c08410 0bf4cc33c6ea8ed70266e412aa802da2 337 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 2.9E-78 T 12-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TSC_c08410 0bf4cc33c6ea8ed70266e412aa802da2 337 Gene3D G3DSA:1.10.3730.40 182 336 2.4E-68 T 12-10-2018 TSC_c08410 0bf4cc33c6ea8ed70266e412aa802da2 337 SUPERFAMILY SSF48179 183 329 1.62E-67 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSC_c08410 0bf4cc33c6ea8ed70266e412aa802da2 337 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 327 4.5E-138 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TSC_c08410 0bf4cc33c6ea8ed70266e412aa802da2 337 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 329 45.84 T 12-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 TSC_c08410 0bf4cc33c6ea8ed70266e412aa802da2 337 Gene3D G3DSA:3.40.50.720 1 181 9.4E-80 T 12-10-2018 TSC_c20490 f34ced0d6cdca655dfd40f905e0758ad 1492 SUPERFAMILY SSF56235 17 387 2.32E-77 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSC_c20490 f34ced0d6cdca655dfd40f905e0758ad 1492 Pfam PF01493 GXGXG motif 1372 1407 3.7E-5 T 12-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 TSC_c20490 f34ced0d6cdca655dfd40f905e0758ad 1492 Pfam PF01493 GXGXG motif 1227 1353 1.1E-17 T 12-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 TSC_c20490 f34ced0d6cdca655dfd40f905e0758ad 1492 SUPERFAMILY SSF69336 1201 1488 8.89E-45 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 TSC_c20490 f34ced0d6cdca655dfd40f905e0758ad 1492 Gene3D G3DSA:3.20.20.70 472 1166 0.0 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c20490 f34ced0d6cdca655dfd40f905e0758ad 1492 Gene3D G3DSA:3.60.20.10 17 532 0.0 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSC_c20490 f34ced0d6cdca655dfd40f905e0758ad 1492 Pfam PF04898 Glutamate synthase central domain 449 725 2.1E-60 T 12-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 TSC_c20490 f34ced0d6cdca655dfd40f905e0758ad 1492 Gene3D G3DSA:3.20.20.70 414 771 0.0 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c20490 f34ced0d6cdca655dfd40f905e0758ad 1492 Pfam PF01645 Conserved region in glutamate synthase 788 1149 4.9E-106 T 12-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 TSC_c20490 f34ced0d6cdca655dfd40f905e0758ad 1492 SUPERFAMILY SSF51395 459 1167 6.72E-165 T 12-10-2018 TSC_c20490 f34ced0d6cdca655dfd40f905e0758ad 1492 Pfam PF00310 Glutamine amidotransferases class-II 17 380 9.0E-45 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TSC_c20490 f34ced0d6cdca655dfd40f905e0758ad 1492 Gene3D G3DSA:2.160.20.60 1210 1492 2.3E-64 T 12-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 TSC_c07000 581a05d756fc11581c80d4dce66f7712 162 ProSitePatterns PS00893 Nudix box signature. 59 80 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TSC_c07000 581a05d756fc11581c80d4dce66f7712 162 SUPERFAMILY SSF55811 6 156 1.1E-38 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSC_c07000 581a05d756fc11581c80d4dce66f7712 162 PRINTS PR00502 NUDIX hydrolase family signature 54 68 4.0E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSC_c07000 581a05d756fc11581c80d4dce66f7712 162 PRINTS PR00502 NUDIX hydrolase family signature 68 83 4.0E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSC_c07000 581a05d756fc11581c80d4dce66f7712 162 Pfam PF00293 NUDIX domain 25 144 2.3E-20 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSC_c07000 581a05d756fc11581c80d4dce66f7712 162 Gene3D G3DSA:3.90.79.10 1 162 8.6E-56 T 12-10-2018 TSC_c06720 06fde1abd9a98f27b96106632db55829 682 Gene3D G3DSA:1.20.1060.10 366 418 3.8E-7 T 12-10-2018 TSC_c06720 06fde1abd9a98f27b96106632db55829 682 PRINTS PR00868 DNA-polymerase family A (pol I) signature 592 608 6.1E-27 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c06720 06fde1abd9a98f27b96106632db55829 682 PRINTS PR00868 DNA-polymerase family A (pol I) signature 510 535 6.1E-27 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c06720 06fde1abd9a98f27b96106632db55829 682 PRINTS PR00868 DNA-polymerase family A (pol I) signature 621 634 6.1E-27 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c06720 06fde1abd9a98f27b96106632db55829 682 PRINTS PR00868 DNA-polymerase family A (pol I) signature 486 499 6.1E-27 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c06720 06fde1abd9a98f27b96106632db55829 682 PRINTS PR00868 DNA-polymerase family A (pol I) signature 415 437 6.1E-27 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c06720 06fde1abd9a98f27b96106632db55829 682 Pfam PF00476 DNA polymerase family A 327 675 3.7E-74 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c06720 06fde1abd9a98f27b96106632db55829 682 SUPERFAMILY SSF53098 138 307 3.8E-25 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c06720 06fde1abd9a98f27b96106632db55829 682 Gene3D G3DSA:3.30.70.370 423 674 6.6E-67 T 12-10-2018 TSC_c06720 06fde1abd9a98f27b96106632db55829 682 Gene3D G3DSA:1.10.150.20 465 599 6.6E-67 T 12-10-2018 TSC_c06720 06fde1abd9a98f27b96106632db55829 682 Gene3D G3DSA:3.30.420.10 136 315 3.0E-22 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSC_c06720 06fde1abd9a98f27b96106632db55829 682 ProSitePatterns PS00447 DNA polymerase family A signature. 510 529 - T 12-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c06720 06fde1abd9a98f27b96106632db55829 682 SUPERFAMILY SSF56672 298 676 1.05E-95 T 12-10-2018 TSC_c06720 06fde1abd9a98f27b96106632db55829 682 Pfam PF01612 3'-5' exonuclease 141 285 1.7E-12 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TSC_c06720 06fde1abd9a98f27b96106632db55829 682 SMART SM00474 131 293 1.1E-6 T 12-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 TSC_c06720 06fde1abd9a98f27b96106632db55829 682 SMART SM00482 442 638 4.3E-56 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c12150 6881dbdc7ee5733c569e880f39cfa0e4 323 SUPERFAMILY SSF47240 41 284 1.78E-75 T 12-10-2018 IPR009078 Ferritin-like superfamily TSC_c12150 6881dbdc7ee5733c569e880f39cfa0e4 323 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 21 309 1.1E-153 T 12-10-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.149 TSC_c12150 6881dbdc7ee5733c569e880f39cfa0e4 323 Gene3D G3DSA:1.20.1260.10 14 323 2.0E-121 T 12-10-2018 IPR012347 Ferritin-like TSC_c12150 6881dbdc7ee5733c569e880f39cfa0e4 323 Pfam PF05138 Phenylacetic acid catabolic protein 31 305 2.4E-93 T 12-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 TSC_c13900 0a7da4c54a36dc7c5eec11ee108d160b 434 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 418 1.8E-162 T 12-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 TSC_c13900 0a7da4c54a36dc7c5eec11ee108d160b 434 Gene3D G3DSA:1.20.120.140 5 303 1.1E-124 T 12-10-2018 TSC_c13900 0a7da4c54a36dc7c5eec11ee108d160b 434 SMART SM00382 97 244 4.1E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c13900 0a7da4c54a36dc7c5eec11ee108d160b 434 Gene3D G3DSA:1.10.260.30 319 433 6.6E-39 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TSC_c13900 0a7da4c54a36dc7c5eec11ee108d160b 434 SUPERFAMILY SSF52540 92 295 9.0E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c13900 0a7da4c54a36dc7c5eec11ee108d160b 434 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 5.1E-19 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSC_c13900 0a7da4c54a36dc7c5eec11ee108d160b 434 SMART SM00963 1 86 1.0E-27 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSC_c13900 0a7da4c54a36dc7c5eec11ee108d160b 434 SUPERFAMILY SSF47364 1 89 1.57E-23 T 12-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 TSC_c13900 0a7da4c54a36dc7c5eec11ee108d160b 434 Pfam PF02978 Signal peptide binding domain 320 417 1.8E-30 T 12-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TSC_c13900 0a7da4c54a36dc7c5eec11ee108d160b 434 Gene3D G3DSA:3.40.50.300 90 282 1.1E-124 T 12-10-2018 TSC_c13900 0a7da4c54a36dc7c5eec11ee108d160b 434 Pfam PF00448 SRP54-type protein, GTPase domain 99 293 2.7E-69 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSC_c13900 0a7da4c54a36dc7c5eec11ee108d160b 434 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 266 279 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSC_c13900 0a7da4c54a36dc7c5eec11ee108d160b 434 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 432 32.864 T 12-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 TSC_c13900 0a7da4c54a36dc7c5eec11ee108d160b 434 SUPERFAMILY SSF47446 295 420 1.83E-36 T 12-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 TSC_c13900 0a7da4c54a36dc7c5eec11ee108d160b 434 SMART SM00962 98 293 3.3E-107 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 Gene3D G3DSA:3.30.420.40 177 360 1.3E-154 T 12-10-2018 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 SUPERFAMILY SSF53067 183 376 1.98E-66 T 12-10-2018 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 Gene3D G3DSA:2.60.34.10 371 554 9.3E-80 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 SUPERFAMILY SSF100920 378 534 8.63E-63 T 12-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 188 201 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 618 36.932 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 Pfam PF00012 Hsp70 protein 4 593 8.5E-247 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 Gene3D G3DSA:3.30.420.40 5 370 1.3E-154 T 12-10-2018 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 Gene3D G3DSA:3.90.640.10 221 310 1.3E-154 T 12-10-2018 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 PRINTS PR00301 70kDa heat shock protein signature 382 401 1.0E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 PRINTS PR00301 70kDa heat shock protein signature 3 16 1.0E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 PRINTS PR00301 70kDa heat shock protein signature 194 204 1.0E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 PRINTS PR00301 70kDa heat shock protein signature 359 379 1.0E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 PRINTS PR00301 70kDa heat shock protein signature 135 155 1.0E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 PRINTS PR00301 70kDa heat shock protein signature 53 61 1.0E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 PRINTS PR00301 70kDa heat shock protein signature 328 344 1.0E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 PRINTS PR00301 70kDa heat shock protein signature 31 43 1.0E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 PRINTS PR00301 70kDa heat shock protein signature 463 479 1.0E-74 T 12-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 593 4.2E-284 T 12-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 SUPERFAMILY SSF53067 2 180 5.7E-63 T 12-10-2018 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TSC_c20270 33b8f9ac83adae31e2a7f76c363c2e62 619 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 331 345 - T 12-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 TSC_c22400 83ff2f21727381510310cefaa45e4f60 93 PIRSF PIRSF002144 1 93 2.0E-34 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22400 83ff2f21727381510310cefaa45e4f60 93 Gene3D G3DSA:3.30.860.10 1 93 7.4E-45 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22400 83ff2f21727381510310cefaa45e4f60 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 5.3E-46 T 12-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 TSC_c22400 83ff2f21727381510310cefaa45e4f60 93 SUPERFAMILY SSF54570 3 85 5.89E-37 T 12-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22400 83ff2f21727381510310cefaa45e4f60 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.746 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22400 83ff2f21727381510310cefaa45e4f60 93 Pfam PF00203 Ribosomal protein S19 3 83 3.8E-37 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22400 83ff2f21727381510310cefaa45e4f60 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 12-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22400 83ff2f21727381510310cefaa45e4f60 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 2.0E-26 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22400 83ff2f21727381510310cefaa45e4f60 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 2.0E-26 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22400 83ff2f21727381510310cefaa45e4f60 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 2.0E-26 T 12-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c09150 72e30074e88809b187ae54ac643f5a15 571 Gene3D G3DSA:1.10.10.2480 1 68 1.1E-27 T 12-10-2018 TSC_c09150 72e30074e88809b187ae54ac643f5a15 571 SUPERFAMILY SSF50447 244 326 4.42E-19 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSC_c09150 72e30074e88809b187ae54ac643f5a15 571 ProSitePatterns PS01176 Initiation factor 2 signature. 524 546 - T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TSC_c09150 72e30074e88809b187ae54ac643f5a15 571 Gene3D G3DSA:2.40.30.10 475 571 2.6E-35 T 12-10-2018 TSC_c09150 72e30074e88809b187ae54ac643f5a15 571 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 3 569 3.4E-204 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TSC_c09150 72e30074e88809b187ae54ac643f5a15 571 SUPERFAMILY SSF52156 356 480 1.57E-32 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TSC_c09150 72e30074e88809b187ae54ac643f5a15 571 SUPERFAMILY SSF50447 474 570 2.08E-31 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSC_c09150 72e30074e88809b187ae54ac643f5a15 571 SUPERFAMILY SSF52540 55 243 5.23E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c09150 72e30074e88809b187ae54ac643f5a15 571 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 74 230 4.6E-32 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSC_c09150 72e30074e88809b187ae54ac643f5a15 571 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 571 14.548 T 12-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 TSC_c09150 72e30074e88809b187ae54ac643f5a15 571 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 48 2.2E-15 T 12-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal TSC_c09150 72e30074e88809b187ae54ac643f5a15 571 Gene3D G3DSA:2.40.30.10 241 363 1.5E-41 T 12-10-2018 TSC_c09150 72e30074e88809b187ae54ac643f5a15 571 Gene3D G3DSA:3.40.50.300 69 240 3.2E-75 T 12-10-2018 TSC_c09150 72e30074e88809b187ae54ac643f5a15 571 Pfam PF11987 Translation-initiation factor 2 360 462 1.8E-31 T 12-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 TSC_c09150 72e30074e88809b187ae54ac643f5a15 571 Gene3D G3DSA:3.40.50.10050 367 474 1.5E-35 T 12-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily TSC_c09150 72e30074e88809b187ae54ac643f5a15 571 Pfam PF00009 Elongation factor Tu GTP binding domain 76 232 8.9E-35 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c15240 890a5e5daed740040f34a7937a30d42c 262 Pfam PF04085 rod shape-determining protein MreC 115 259 5.3E-29 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 TSC_c15240 890a5e5daed740040f34a7937a30d42c 262 Gene3D G3DSA:2.40.10.340 113 258 7.1E-27 T 12-10-2018 TSC_c15240 890a5e5daed740040f34a7937a30d42c 262 PIRSF PIRSF038471 3 262 4.0E-38 T 12-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 TSC_c15240 890a5e5daed740040f34a7937a30d42c 262 Gene3D G3DSA:2.40.10.350 172 247 7.1E-27 T 12-10-2018 TSC_c00370 86ba6721697ef5646d05e9f4f924fd5e 249 SUPERFAMILY SSF64167 1 248 1.44E-82 T 12-10-2018 TSC_c00370 86ba6721697ef5646d05e9f4f924fd5e 249 Pfam PF01975 Survival protein SurE 3 185 1.2E-55 T 12-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TSC_c00370 86ba6721697ef5646d05e9f4f924fd5e 249 Gene3D G3DSA:3.40.1210.10 1 244 6.0E-88 T 12-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TSC_c00370 86ba6721697ef5646d05e9f4f924fd5e 249 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 234 9.7E-71 T 12-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TSC_c00370 86ba6721697ef5646d05e9f4f924fd5e 249 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 249 37.265 T 12-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TSC_c07050 00e0bb8032173cecbce1310f7b1e0622 405 Gene3D G3DSA:3.30.70.260 335 403 1.8E-22 T 12-10-2018 TSC_c07050 00e0bb8032173cecbce1310f7b1e0622 405 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 64 401 8.6E-104 T 12-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSC_c07050 00e0bb8032173cecbce1310f7b1e0622 405 Pfam PF00696 Amino acid kinase family 3 229 1.5E-52 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSC_c07050 00e0bb8032173cecbce1310f7b1e0622 405 Pfam PF13840 ACT domain 337 397 3.0E-9 T 12-10-2018 IPR027795 CASTOR, ACT domain TSC_c07050 00e0bb8032173cecbce1310f7b1e0622 405 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 402 1.3E-123 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSC_c07050 00e0bb8032173cecbce1310f7b1e0622 405 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 12-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSC_c07050 00e0bb8032173cecbce1310f7b1e0622 405 SUPERFAMILY SSF55021 249 327 9.97E-16 T 12-10-2018 TSC_c07050 00e0bb8032173cecbce1310f7b1e0622 405 PIRSF PIRSF000726 1 63 2.3E-19 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSC_c07050 00e0bb8032173cecbce1310f7b1e0622 405 PIRSF PIRSF000726 59 405 6.6E-108 T 12-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSC_c07050 00e0bb8032173cecbce1310f7b1e0622 405 SUPERFAMILY SSF55021 333 403 9.67E-19 T 12-10-2018 TSC_c07050 00e0bb8032173cecbce1310f7b1e0622 405 Gene3D G3DSA:3.30.70.260 259 334 1.9E-30 T 12-10-2018 TSC_c07050 00e0bb8032173cecbce1310f7b1e0622 405 Gene3D G3DSA:3.40.1160.10 1 254 3.0E-87 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSC_c07050 00e0bb8032173cecbce1310f7b1e0622 405 SUPERFAMILY SSF53633 4 240 5.11E-73 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSC_c07050 00e0bb8032173cecbce1310f7b1e0622 405 Pfam PF01842 ACT domain 266 322 7.7E-9 T 12-10-2018 IPR002912 ACT domain TSC_c14880 0a62a2246333807eb2c725697272e5cd 254 Gene3D G3DSA:3.40.50.150 63 254 1.2E-63 T 12-10-2018 TSC_c14880 0a62a2246333807eb2c725697272e5cd 254 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 2 254 30.142 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 TSC_c14880 0a62a2246333807eb2c725697272e5cd 254 SUPERFAMILY SSF53335 46 249 7.92E-54 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c14880 0a62a2246333807eb2c725697272e5cd 254 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 51 250 3.4E-54 T 12-10-2018 TSC_c14880 0a62a2246333807eb2c725697272e5cd 254 PIRSF PIRSF000401 45 253 4.2E-57 T 12-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 TSC_c14880 0a62a2246333807eb2c725697272e5cd 254 Gene3D G3DSA:3.30.70.1170 1 59 2.7E-28 T 12-10-2018 TSC_c09790 480d6514269a7874760f00c77cd49a18 445 SUPERFAMILY SSF51246 327 444 3.71E-43 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TSC_c09790 480d6514269a7874760f00c77cd49a18 445 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 151 165 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSC_c09790 480d6514269a7874760f00c77cd49a18 445 SUPERFAMILY SSF56059 82 344 1.68E-75 T 12-10-2018 TSC_c09790 480d6514269a7874760f00c77cd49a18 445 SUPERFAMILY SSF52440 1 112 3.67E-46 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSC_c09790 480d6514269a7874760f00c77cd49a18 445 Pfam PF02785 Biotin carboxylase C-terminal domain 332 440 1.6E-40 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSC_c09790 480d6514269a7874760f00c77cd49a18 445 SMART SM01209 113 288 0.0021 T 12-10-2018 TSC_c09790 480d6514269a7874760f00c77cd49a18 445 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 282 289 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSC_c09790 480d6514269a7874760f00c77cd49a18 445 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 443 7.3E-210 T 12-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 TSC_c09790 480d6514269a7874760f00c77cd49a18 445 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 109 1.7E-42 T 12-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSC_c09790 480d6514269a7874760f00c77cd49a18 445 Gene3D G3DSA:3.30.470.130 1 445 7.6E-197 T 12-10-2018 TSC_c09790 480d6514269a7874760f00c77cd49a18 445 SMART SM00878 332 440 2.3E-66 T 12-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSC_c09790 480d6514269a7874760f00c77cd49a18 445 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 114 317 2.2E-78 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSC_c09500 4f433397e05c8df73efe71f96e0e25f7 180 Pfam PF02660 Glycerol-3-phosphate acyltransferase 7 178 1.5E-37 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TSC_c09500 4f433397e05c8df73efe71f96e0e25f7 180 SMART SM01207 6 178 8.1E-42 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TSC_c09500 4f433397e05c8df73efe71f96e0e25f7 180 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 3 180 13.496 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TSC_c13180 899204819475ae9d1847d281ab480c56 577 SUPERFAMILY SSF47203 248 416 3.38E-52 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSC_c13180 899204819475ae9d1847d281ab480c56 577 SUPERFAMILY SSF56645 20 261 8.64E-76 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSC_c13180 899204819475ae9d1847d281ab480c56 577 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 147 159 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSC_c13180 899204819475ae9d1847d281ab480c56 577 Gene3D G3DSA:1.10.540.10 1 143 2.9E-47 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSC_c13180 899204819475ae9d1847d281ab480c56 577 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 145 238 6.2E-24 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSC_c13180 899204819475ae9d1847d281ab480c56 577 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 30 141 3.8E-29 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSC_c13180 899204819475ae9d1847d281ab480c56 577 Gene3D G3DSA:1.20.140.10 416 575 2.1E-44 T 12-10-2018 TSC_c13180 899204819475ae9d1847d281ab480c56 577 Gene3D G3DSA:1.20.140.10 250 415 1.2E-58 T 12-10-2018 TSC_c13180 899204819475ae9d1847d281ab480c56 577 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 371 390 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSC_c13180 899204819475ae9d1847d281ab480c56 577 Gene3D G3DSA:2.40.110.10 144 249 1.6E-36 T 12-10-2018 TSC_c13180 899204819475ae9d1847d281ab480c56 577 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 250 408 1.8E-41 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSC_c09870 06c92180fa8ac461439292c561c197b2 224 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 8 220 8.0E-72 T 12-10-2018 IPR022493 Integral membrane YkoY TSC_c09870 06c92180fa8ac461439292c561c197b2 224 Pfam PF03741 Integral membrane protein TerC family 11 181 4.6E-50 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 TSC_c20450 71c7a0ee4a608d51e86cb2336bd3bbc7 518 Pfam PF13181 Tetratricopeptide repeat 166 189 0.15 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c20450 71c7a0ee4a608d51e86cb2336bd3bbc7 518 SUPERFAMILY SSF48452 140 220 7.37E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c20450 71c7a0ee4a608d51e86cb2336bd3bbc7 518 Gene3D G3DSA:1.10.530.10 365 517 2.7E-38 T 12-10-2018 TSC_c20450 71c7a0ee4a608d51e86cb2336bd3bbc7 518 SUPERFAMILY SSF53955 370 516 3.97E-38 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily TSC_c20450 71c7a0ee4a608d51e86cb2336bd3bbc7 518 Gene3D G3DSA:1.25.40.10 28 283 7.6E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c20450 71c7a0ee4a608d51e86cb2336bd3bbc7 518 Pfam PF01464 Transglycosylase SLT domain 378 484 1.4E-23 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 TSC_c10570 7c87b34e345e46ac86992d17909f00c7 331 Pfam PF00155 Aminotransferase class I and II 58 322 1.0E-23 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSC_c10570 7c87b34e345e46ac86992d17909f00c7 331 Gene3D G3DSA:3.40.640.10 32 233 2.8E-60 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c10570 7c87b34e345e46ac86992d17909f00c7 331 Gene3D G3DSA:3.90.1150.10 20 323 2.8E-60 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c10570 7c87b34e345e46ac86992d17909f00c7 331 SUPERFAMILY SSF53383 15 327 1.15E-50 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c13790 264c1f7907fd76dfec471405c0c88783 530 Gene3D G3DSA:2.130.10.10 176 360 2.3E-28 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TSC_c13790 264c1f7907fd76dfec471405c0c88783 530 Gene3D G3DSA:2.130.10.10 7 175 1.3E-18 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TSC_c13790 264c1f7907fd76dfec471405c0c88783 530 SMART SM00564 101 131 3.4 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSC_c13790 264c1f7907fd76dfec471405c0c88783 530 SMART SM00564 279 309 240.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSC_c13790 264c1f7907fd76dfec471405c0c88783 530 SMART SM00564 236 269 0.013 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSC_c13790 264c1f7907fd76dfec471405c0c88783 530 SMART SM00564 16 52 500.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSC_c13790 264c1f7907fd76dfec471405c0c88783 530 SMART SM00564 61 92 21.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSC_c13790 264c1f7907fd76dfec471405c0c88783 530 SMART SM00564 197 228 31.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSC_c13790 264c1f7907fd76dfec471405c0c88783 530 SUPERFAMILY SSF50998 44 343 1.07E-33 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TSC_c13790 264c1f7907fd76dfec471405c0c88783 530 Pfam PF13360 PQQ-like domain 38 126 4.9E-6 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TSC_c13790 264c1f7907fd76dfec471405c0c88783 530 Pfam PF13360 PQQ-like domain 180 319 2.3E-18 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TSC_c08460 15489110aaa877988bab28dc73f720af 340 SMART SM00382 52 237 7.3E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c08460 15489110aaa877988bab28dc73f720af 340 Pfam PF00005 ABC transporter 44 187 8.6E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c08460 15489110aaa877988bab28dc73f720af 340 SUPERFAMILY SSF52540 36 259 4.47E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c08460 15489110aaa877988bab28dc73f720af 340 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c08460 15489110aaa877988bab28dc73f720af 340 Gene3D G3DSA:3.40.50.300 31 269 3.5E-54 T 12-10-2018 TSC_c23050 747e6ce3cd103e67a8c35a485540cf7d 352 SUPERFAMILY SSF52283 22 326 9.35E-42 T 12-10-2018 TSC_c23050 747e6ce3cd103e67a8c35a485540cf7d 352 SMART SM01003 4 146 3.1E-51 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TSC_c23050 747e6ce3cd103e67a8c35a485540cf7d 352 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 22 146 1.8E-37 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TSC_c23050 747e6ce3cd103e67a8c35a485540cf7d 352 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 153 327 1.3E-43 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TSC_c23050 747e6ce3cd103e67a8c35a485540cf7d 352 Gene3D G3DSA:3.40.50.720 22 329 2.4E-100 T 12-10-2018 TSC_c23050 747e6ce3cd103e67a8c35a485540cf7d 352 Gene3D G3DSA:3.40.50.720 139 307 2.4E-100 T 12-10-2018 TSC_c23050 747e6ce3cd103e67a8c35a485540cf7d 352 SUPERFAMILY SSF51735 146 304 8.06E-29 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c23050 747e6ce3cd103e67a8c35a485540cf7d 352 SMART SM01002 157 299 2.8E-42 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TSC_c05830 cfda780faafd5fb3cffeeb937ff12927 408 PIRSF PIRSF000447 1 408 2.1E-195 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 TSC_c05830 cfda780faafd5fb3cffeeb937ff12927 408 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 152 168 - T 12-10-2018 IPR018201 Beta-ketoacyl synthase, active site TSC_c05830 cfda780faafd5fb3cffeeb937ff12927 408 SMART SM00825 Beta-ketoacyl synthase 4 399 3.6E-16 T 12-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain TSC_c05830 cfda780faafd5fb3cffeeb937ff12927 408 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 2 406 2.9E-191 T 12-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 TSC_c05830 cfda780faafd5fb3cffeeb937ff12927 408 SUPERFAMILY SSF53901 212 407 6.53E-72 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c05830 cfda780faafd5fb3cffeeb937ff12927 408 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1 244 1.5E-60 T 12-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal TSC_c05830 cfda780faafd5fb3cffeeb937ff12927 408 Gene3D G3DSA:3.40.47.10 1 252 1.5E-93 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c05830 cfda780faafd5fb3cffeeb937ff12927 408 SUPERFAMILY SSF53901 1 249 1.79E-79 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c05830 cfda780faafd5fb3cffeeb937ff12927 408 Gene3D G3DSA:3.40.47.10 254 397 1.9E-57 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c05830 cfda780faafd5fb3cffeeb937ff12927 408 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 252 366 7.1E-41 T 12-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal TSC_c08710 3f1cb3abc3ef00be5d2d9f39a8166c8a 381 Gene3D G3DSA:3.30.750.80 67 171 1.5E-28 T 12-10-2018 TSC_c08710 3f1cb3abc3ef00be5d2d9f39a8166c8a 381 Gene3D G3DSA:3.40.50.150 172 380 3.1E-69 T 12-10-2018 TSC_c08710 3f1cb3abc3ef00be5d2d9f39a8166c8a 381 SUPERFAMILY SSF53335 74 376 6.6E-69 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c08710 3f1cb3abc3ef00be5d2d9f39a8166c8a 381 Gene3D G3DSA:2.30.130.10 1 66 4.8E-28 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 TSC_c08710 3f1cb3abc3ef00be5d2d9f39a8166c8a 381 SUPERFAMILY SSF88697 1 64 1.09E-30 T 12-10-2018 IPR015947 PUA-like superfamily TSC_c08710 3f1cb3abc3ef00be5d2d9f39a8166c8a 381 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 109 342 4.1E-20 T 12-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 TSC_c15360 2f4bbce029b7b51ddc6f35de040e3128 320 Pfam PF13531 Bacterial extracellular solute-binding protein 51 315 2.5E-40 T 12-10-2018 TSC_c15360 2f4bbce029b7b51ddc6f35de040e3128 320 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 55 181 2.0E-28 T 12-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 TSC_c15360 2f4bbce029b7b51ddc6f35de040e3128 320 SUPERFAMILY SSF53850 49 318 3.44E-47 T 12-10-2018 TSC_c03000 dc2bc8ad0a1bc1d4bbec254838f9ce0c 375 Gene3D G3DSA:3.90.1150.10 250 374 2.2E-39 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c03000 dc2bc8ad0a1bc1d4bbec254838f9ce0c 375 PIRSF PIRSF000390 1 374 2.3E-113 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TSC_c03000 dc2bc8ad0a1bc1d4bbec254838f9ce0c 375 SUPERFAMILY SSF53383 3 372 8.57E-108 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c03000 dc2bc8ad0a1bc1d4bbec254838f9ce0c 375 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 18 370 5.7E-106 T 12-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase TSC_c03000 dc2bc8ad0a1bc1d4bbec254838f9ce0c 375 Gene3D G3DSA:3.40.640.10 1 248 2.2E-89 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c24200 8462b89cc5713a7b130abcbaf060d4b2 666 SUPERFAMILY SSF52540 32 581 2.61E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c24200 8462b89cc5713a7b130abcbaf060d4b2 666 Pfam PF04851 Type III restriction enzyme, res subunit 13 135 1.2E-11 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TSC_c24200 8462b89cc5713a7b130abcbaf060d4b2 666 SMART SM00487 6 419 7.1E-28 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSC_c24200 8462b89cc5713a7b130abcbaf060d4b2 666 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 9 643 0.0 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 TSC_c24200 8462b89cc5713a7b130abcbaf060d4b2 666 Pfam PF00271 Helicase conserved C-terminal domain 429 539 1.6E-17 T 12-10-2018 IPR001650 Helicase, C-terminal TSC_c24200 8462b89cc5713a7b130abcbaf060d4b2 666 Pfam PF12344 Ultra-violet resistance protein B 546 588 1.8E-21 T 12-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain TSC_c24200 8462b89cc5713a7b130abcbaf060d4b2 666 SUPERFAMILY SSF52540 7 409 7.82E-125 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c24200 8462b89cc5713a7b130abcbaf060d4b2 666 Pfam PF02151 UvrB/uvrC motif 611 645 9.7E-9 T 12-10-2018 IPR001943 UVR domain GO:0005515 TSC_c24200 8462b89cc5713a7b130abcbaf060d4b2 666 SUPERFAMILY SSF46600 606 647 1.44E-10 T 12-10-2018 IPR036876 UVR domain superfamily TSC_c24200 8462b89cc5713a7b130abcbaf060d4b2 666 SMART SM00490 454 540 3.5E-17 T 12-10-2018 IPR001650 Helicase, C-terminal TSC_c24200 8462b89cc5713a7b130abcbaf060d4b2 666 Gene3D G3DSA:4.10.860.10 598 648 2.1E-6 T 12-10-2018 TSC_c24200 8462b89cc5713a7b130abcbaf060d4b2 666 Gene3D G3DSA:3.40.50.300 409 590 4.1E-49 T 12-10-2018 TSC_c24200 8462b89cc5713a7b130abcbaf060d4b2 666 Gene3D G3DSA:3.40.50.300 1 233 3.4E-70 T 12-10-2018 TSC_c24200 8462b89cc5713a7b130abcbaf060d4b2 666 Gene3D G3DSA:3.40.50.300 263 408 8.9E-54 T 12-10-2018 TSC_c24200 8462b89cc5713a7b130abcbaf060d4b2 666 Hamap MF_00204 UvrABC system protein B [uvrB]. 1 646 42.483 T 12-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 TSC_c22790 7fdaf7dcb37ae08e0d53e4abcb32de9d 336 Pfam PF03739 Predicted permease YjgP/YjgQ family 4 334 1.7E-50 T 12-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 TSC_c05050 d714108090f153a61cfd666104b28249 237 PIRSF PIRSF039137 1 237 5.8E-113 T 12-10-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 TSC_c05050 d714108090f153a61cfd666104b28249 237 Gene3D G3DSA:3.40.50.300 2 237 3.0E-67 T 12-10-2018 TSC_c05050 d714108090f153a61cfd666104b28249 237 Pfam PF00005 ABC transporter 19 164 2.9E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c05050 d714108090f153a61cfd666104b28249 237 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c05050 d714108090f153a61cfd666104b28249 237 SUPERFAMILY SSF52540 3 235 1.66E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c05050 d714108090f153a61cfd666104b28249 237 SMART SM00382 28 234 2.1E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c10720 0bc2112a68b7a04521d2cdc730e4ca55 385 Gene3D G3DSA:3.40.630.10 19 372 1.3E-89 T 12-10-2018 TSC_c10720 0bc2112a68b7a04521d2cdc730e4ca55 385 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 112 150 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TSC_c10720 0bc2112a68b7a04521d2cdc730e4ca55 385 SUPERFAMILY SSF55031 186 289 8.22E-17 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSC_c10720 0bc2112a68b7a04521d2cdc730e4ca55 385 Pfam PF07687 Peptidase dimerisation domain 184 290 6.1E-16 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain TSC_c10720 0bc2112a68b7a04521d2cdc730e4ca55 385 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 17 374 5.3E-70 T 12-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase TSC_c10720 0bc2112a68b7a04521d2cdc730e4ca55 385 Pfam PF01546 Peptidase family M20/M25/M40 78 380 1.2E-37 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 TSC_c10720 0bc2112a68b7a04521d2cdc730e4ca55 385 Gene3D G3DSA:3.30.70.360 186 300 1.3E-89 T 12-10-2018 TSC_c10720 0bc2112a68b7a04521d2cdc730e4ca55 385 SUPERFAMILY SSF53187 4 381 2.14E-62 T 12-10-2018 TSC_c10450 f8706d567da472896ad3c52caa19ebb2 483 PIRSF PIRSF000331 1 481 3.7E-186 T 12-10-2018 IPR004925 HpaB/PvcC/4-BUDH TSC_c10450 f8706d567da472896ad3c52caa19ebb2 483 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 4 266 4.8E-98 T 12-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal TSC_c10450 f8706d567da472896ad3c52caa19ebb2 483 Gene3D G3DSA:1.10.3140.10 1 138 8.3E-60 T 12-10-2018 TSC_c10450 f8706d567da472896ad3c52caa19ebb2 483 TIGRFAM TIGR02309 HpaB-1: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component 2 473 4.2E-262 T 12-10-2018 IPR012687 4-HPA 3-monooxygenase large component, Deinococcus-type GO:0010124|GO:0016712|GO:0050660 KEGG: 00350+1.14.14.9|MetaCyc: PWY-7431 TSC_c10450 f8706d567da472896ad3c52caa19ebb2 483 SUPERFAMILY SSF56645 1 266 1.42E-80 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSC_c10450 f8706d567da472896ad3c52caa19ebb2 483 Gene3D G3DSA:1.20.140.10 269 483 4.5E-94 T 12-10-2018 TSC_c10450 f8706d567da472896ad3c52caa19ebb2 483 Gene3D G3DSA:2.40.110.10 139 268 1.2E-48 T 12-10-2018 TSC_c10450 f8706d567da472896ad3c52caa19ebb2 483 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 273 471 2.1E-70 T 12-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal TSC_c10450 f8706d567da472896ad3c52caa19ebb2 483 SUPERFAMILY SSF47203 257 472 2.09E-65 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSC_c15130 6ec5de285b505678db9cd700d03e56b7 246 PIRSF PIRSF006221 2 246 1.0E-41 T 12-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 TSC_c15130 6ec5de285b505678db9cd700d03e56b7 246 Gene3D G3DSA:3.90.1200.10 69 245 4.0E-38 T 12-10-2018 TSC_c15130 6ec5de285b505678db9cd700d03e56b7 246 Gene3D G3DSA:3.30.200.20 2 64 4.9E-10 T 12-10-2018 TSC_c15130 6ec5de285b505678db9cd700d03e56b7 246 Pfam PF03881 Fructosamine kinase 4 243 4.8E-44 T 12-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 TSC_c15130 6ec5de285b505678db9cd700d03e56b7 246 SUPERFAMILY SSF56112 3 243 1.18E-37 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TSC_c07790 050773e98954e15a35a5b9aff50d8a48 275 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 26 272 2.4E-88 T 12-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 TSC_c07790 050773e98954e15a35a5b9aff50d8a48 275 SUPERFAMILY SSF53167 4 275 2.49E-85 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TSC_c07790 050773e98954e15a35a5b9aff50d8a48 275 Pfam PF01048 Phosphorylase superfamily 27 268 3.0E-43 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TSC_c07790 050773e98954e15a35a5b9aff50d8a48 275 PIRSF PIRSF000477 1 275 4.7E-94 T 12-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 TSC_c07790 050773e98954e15a35a5b9aff50d8a48 275 Gene3D G3DSA:3.40.50.1580 1 274 8.4E-100 T 12-10-2018 TSC_c15350 4df1f278ea7bd18dc40a0750f8c30297 301 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 153 297 4.0E-46 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TSC_c15350 4df1f278ea7bd18dc40a0750f8c30297 301 Gene3D G3DSA:3.40.50.1370 137 287 7.4E-111 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSC_c15350 4df1f278ea7bd18dc40a0750f8c30297 301 Gene3D G3DSA:3.40.50.1370 20 296 7.4E-111 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSC_c15350 4df1f278ea7bd18dc40a0750f8c30297 301 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 10 147 7.9E-43 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TSC_c15350 4df1f278ea7bd18dc40a0750f8c30297 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 52 71 2.0E-22 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSC_c15350 4df1f278ea7bd18dc40a0750f8c30297 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 253 262 2.0E-22 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSC_c15350 4df1f278ea7bd18dc40a0750f8c30297 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 134 145 2.0E-22 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSC_c15350 4df1f278ea7bd18dc40a0750f8c30297 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 288 2.0E-22 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSC_c15350 4df1f278ea7bd18dc40a0750f8c30297 301 PRINTS PR00102 Ornithine carbamoyltransferase signature 217 227 3.7E-23 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSC_c15350 4df1f278ea7bd18dc40a0750f8c30297 301 PRINTS PR00102 Ornithine carbamoyltransferase signature 83 96 3.7E-23 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSC_c15350 4df1f278ea7bd18dc40a0750f8c30297 301 PRINTS PR00102 Ornithine carbamoyltransferase signature 279 290 3.7E-23 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSC_c15350 4df1f278ea7bd18dc40a0750f8c30297 301 PRINTS PR00102 Ornithine carbamoyltransferase signature 123 137 3.7E-23 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSC_c15350 4df1f278ea7bd18dc40a0750f8c30297 301 PRINTS PR00102 Ornithine carbamoyltransferase signature 50 64 3.7E-23 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSC_c15350 4df1f278ea7bd18dc40a0750f8c30297 301 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 9 301 73.582 T 12-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 TSC_c15350 4df1f278ea7bd18dc40a0750f8c30297 301 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 10 300 7.5E-106 T 12-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 TSC_c15350 4df1f278ea7bd18dc40a0750f8c30297 301 SUPERFAMILY SSF53671 8 300 4.06E-91 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSC_c04850 340d8847d834baf212e1be439c34256a 227 SMART SM00448 2 112 7.3E-37 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c04850 340d8847d834baf212e1be439c34256a 227 SUPERFAMILY SSF52172 1 167 7.55E-38 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c04850 340d8847d834baf212e1be439c34256a 227 Pfam PF00072 Response regulator receiver domain 4 113 5.5E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c04850 340d8847d834baf212e1be439c34256a 227 Gene3D G3DSA:3.40.50.2300 1 121 2.1E-34 T 12-10-2018 TSC_c04850 340d8847d834baf212e1be439c34256a 227 SMART SM00862 143 218 3.8E-26 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c04850 340d8847d834baf212e1be439c34256a 227 Gene3D G3DSA:1.10.10.10 122 219 4.9E-31 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c04850 340d8847d834baf212e1be439c34256a 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 217 1.4E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c05820 59937682e21c2e1faa8a2ecb80ef08af 376 SUPERFAMILY SSF109604 27 375 1.44E-84 T 12-10-2018 TSC_c05820 59937682e21c2e1faa8a2ecb80ef08af 376 Pfam PF13286 Phosphohydrolase-associated domain 287 373 2.8E-25 T 12-10-2018 IPR026875 Phosphohydrolase-associated domain TSC_c05820 59937682e21c2e1faa8a2ecb80ef08af 376 Pfam PF01966 HD domain 76 200 4.0E-17 T 12-10-2018 IPR006674 HD domain TSC_c05820 59937682e21c2e1faa8a2ecb80ef08af 376 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 39 173 4.0E-61 T 12-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 TSC_c05820 59937682e21c2e1faa8a2ecb80ef08af 376 SMART SM00471 72 210 3.1E-13 T 12-10-2018 IPR003607 HD/PDEase domain TSC_c05820 59937682e21c2e1faa8a2ecb80ef08af 376 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 16 375 38.183 T 12-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 TSC_c05820 59937682e21c2e1faa8a2ecb80ef08af 376 Gene3D G3DSA:1.10.3210.10 1 376 2.5E-155 T 12-10-2018 TSC_c16370 d4770153287dfe8f3bd9f4eeb3ad6318 116 Pfam PF04956 TrbC/VIRB2 family 18 109 3.6E-7 T 12-10-2018 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 TSC_c23600 b57dc5651ec0736d153cb44e10ce03e5 262 PIRSF PIRSF020623 1 255 1.0E-72 T 12-10-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 TSC_c23600 b57dc5651ec0736d153cb44e10ce03e5 262 Pfam PF08223 PaaX-like protein C-terminal domain 158 246 1.9E-16 T 12-10-2018 IPR013225 PaaX-like, C-terminal TSC_c23600 b57dc5651ec0736d153cb44e10ce03e5 262 Gene3D G3DSA:1.10.10.10 1 82 1.3E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c23600 b57dc5651ec0736d153cb44e10ce03e5 262 Pfam PF07848 PaaX-like protein 2 70 3.0E-24 T 12-10-2018 IPR012906 PaaX-like, N-terminal TSC_c21340 c82f2323cf256638ec9c8c721687377d 136 SUPERFAMILY SSF103196 2 132 6.98E-10 T 12-10-2018 TSC_c21340 c82f2323cf256638ec9c8c721687377d 136 Gene3D G3DSA:3.30.450.30 1 133 1.7E-10 T 12-10-2018 TSC_c23590 c2980151158787780b46634a346dbb65 659 Gene3D G3DSA:3.10.20.30 1 63 3.8E-19 T 12-10-2018 IPR012675 Beta-grasp domain superfamily TSC_c23590 c2980151158787780b46634a346dbb65 659 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 71 648 1.4E-212 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSC_c23590 c2980151158787780b46634a346dbb65 659 Gene3D G3DSA:3.40.50.800 551 656 9.7E-33 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily TSC_c23590 c2980151158787780b46634a346dbb65 659 SUPERFAMILY SSF81271 2 60 1.96E-14 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TSC_c23590 c2980151158787780b46634a346dbb65 659 Gene3D G3DSA:3.30.930.10 235 550 9.9E-120 T 12-10-2018 TSC_c23590 c2980151158787780b46634a346dbb65 659 Pfam PF03129 Anticodon binding domain 559 645 3.4E-22 T 12-10-2018 IPR004154 Anticodon-binding TSC_c23590 c2980151158787780b46634a346dbb65 659 SUPERFAMILY SSF52954 548 652 4.83E-32 T 12-10-2018 TSC_c23590 c2980151158787780b46634a346dbb65 659 Gene3D G3DSA:3.30.54.20 136 195 1.4E-56 T 12-10-2018 TSC_c23590 c2980151158787780b46634a346dbb65 659 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 336 546 9.4E-41 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c23590 c2980151158787780b46634a346dbb65 659 Pfam PF02824 TGS domain 2 60 1.2E-15 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 TSC_c23590 c2980151158787780b46634a346dbb65 659 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 174 228 3.8E-13 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSC_c23590 c2980151158787780b46634a346dbb65 659 SUPERFAMILY SSF55186 62 250 5.62E-54 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TSC_c23590 c2980151158787780b46634a346dbb65 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 344 372 9.5E-53 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSC_c23590 c2980151158787780b46634a346dbb65 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 377 400 9.5E-53 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSC_c23590 c2980151158787780b46634a346dbb65 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 525 538 9.5E-53 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSC_c23590 c2980151158787780b46634a346dbb65 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 482 510 9.5E-53 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSC_c23590 c2980151158787780b46634a346dbb65 659 PRINTS PR01047 Threonyl-tRNA synthetase signature 552 564 9.5E-53 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSC_c23590 c2980151158787780b46634a346dbb65 659 Gene3D G3DSA:3.30.980.10 69 231 1.4E-56 T 12-10-2018 TSC_c23590 c2980151158787780b46634a346dbb65 659 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 65 652 35.542 T 12-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 TSC_c23590 c2980151158787780b46634a346dbb65 659 SMART SM00863 174 228 8.4E-23 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSC_c23590 c2980151158787780b46634a346dbb65 659 SUPERFAMILY SSF55681 252 544 1.17E-91 T 12-10-2018 TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 Gene3D G3DSA:3.30.1360.200 112 252 3.0E-82 T 12-10-2018 TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 Pfam PF07549 SecD/SecF GG Motif 466 489 2.4E-7 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 Pfam PF07549 SecD/SecF GG Motif 32 49 0.012 T 12-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 Gene3D G3DSA:3.30.70.3400 48 258 3.0E-82 T 12-10-2018 TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 550 713 1.1E-54 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 184 414 5.3E-65 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 SUPERFAMILY SSF82866 527 727 2.09E-40 T 12-10-2018 TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 35 422 1.2E-125 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 Gene3D G3DSA:3.30.70.2040 477 559 7.0E-49 T 12-10-2018 TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 PRINTS PR01755 Bacterial translocase SecF protein signature 584 598 8.9E-29 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 PRINTS PR01755 Bacterial translocase SecF protein signature 632 650 8.9E-29 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 PRINTS PR01755 Bacterial translocase SecF protein signature 469 484 8.9E-29 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 PRINTS PR01755 Bacterial translocase SecF protein signature 664 679 8.9E-29 T 12-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 SUPERFAMILY SSF82866 231 427 1.7E-35 T 12-10-2018 TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 442 727 28.014 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 437 38.397 T 12-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 Pfam PF02355 Protein export membrane protein 255 424 1.7E-15 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 Pfam PF02355 Protein export membrane protein 549 725 2.5E-63 T 12-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial TSC_c09130 5ac2dccafe2af041cb4b9bd07717a019 735 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 470 715 4.9E-73 T 12-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 TSC_c14490 1044ac66ad388bb795ffde5f5628a1d9 417 SUPERFAMILY SSF53244 267 407 7.78E-29 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSC_c14490 1044ac66ad388bb795ffde5f5628a1d9 417 Pfam PF02875 Mur ligase family, glutamate ligase domain 267 330 6.9E-6 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TSC_c14490 1044ac66ad388bb795ffde5f5628a1d9 417 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 1 407 26.654 T 12-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSC_c14490 1044ac66ad388bb795ffde5f5628a1d9 417 SUPERFAMILY SSF51984 2 81 6.15E-10 T 12-10-2018 TSC_c14490 1044ac66ad388bb795ffde5f5628a1d9 417 SUPERFAMILY SSF53623 86 228 1.1E-37 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSC_c14490 1044ac66ad388bb795ffde5f5628a1d9 417 Gene3D G3DSA:3.40.50.720 1 82 2.9E-10 T 12-10-2018 TSC_c14490 1044ac66ad388bb795ffde5f5628a1d9 417 Pfam PF08245 Mur ligase middle domain 99 222 1.4E-23 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TSC_c14490 1044ac66ad388bb795ffde5f5628a1d9 417 Gene3D G3DSA:3.40.1190.10 84 250 1.0E-39 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSC_c14490 1044ac66ad388bb795ffde5f5628a1d9 417 Gene3D G3DSA:3.90.190.20 267 403 5.4E-28 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSC_c17770 c5c8534762ef6cc46622bcb10e860eee 324 Pfam PF03576 Peptidase family S58 12 314 1.0E-66 T 12-10-2018 IPR005321 Peptidase S58, DmpA TSC_c17770 c5c8534762ef6cc46622bcb10e860eee 324 SUPERFAMILY SSF56266 12 322 6.8E-72 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TSC_c17770 c5c8534762ef6cc46622bcb10e860eee 324 Gene3D G3DSA:3.60.70.12 8 324 2.9E-110 T 12-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 TSC_c02030 3848f50c554d9d25e19e43ff139cf3db 306 Gene3D G3DSA:3.40.109.10 2 239 9.9E-56 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSC_c02030 3848f50c554d9d25e19e43ff139cf3db 306 SUPERFAMILY SSF55469 3 216 4.58E-54 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSC_c02030 3848f50c554d9d25e19e43ff139cf3db 306 Pfam PF00881 Nitroreductase family 8 161 2.4E-21 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TSC_c14960 0956053f0207295ac544adcd2ca6ed9a 236 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 229 2.4E-70 T 12-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 TSC_c14960 0956053f0207295ac544adcd2ca6ed9a 236 SUPERFAMILY SSF51366 1 232 4.78E-63 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSC_c14960 0956053f0207295ac544adcd2ca6ed9a 236 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 234 32.483 T 12-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 TSC_c14960 0956053f0207295ac544adcd2ca6ed9a 236 Gene3D G3DSA:3.20.20.70 1 235 6.4E-82 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c14960 0956053f0207295ac544adcd2ca6ed9a 236 Pfam PF00977 Histidine biosynthesis protein 3 226 1.2E-68 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 TSC_c00740 921822f9358d06baadc02d320a06dfac 617 SUPERFAMILY SSF52922 501 605 7.07E-17 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSC_c00740 921822f9358d06baadc02d320a06dfac 617 SUPERFAMILY SSF52518 231 490 1.73E-60 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c00740 921822f9358d06baadc02d320a06dfac 617 Gene3D G3DSA:3.40.920.10 2 219 5.9E-17 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSC_c00740 921822f9358d06baadc02d320a06dfac 617 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 3 598 1.3E-176 T 12-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 TSC_c00740 921822f9358d06baadc02d320a06dfac 617 Gene3D G3DSA:3.40.50.970 221 416 1.6E-67 T 12-10-2018 TSC_c00740 921822f9358d06baadc02d320a06dfac 617 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 13 211 4.9E-40 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TSC_c00740 921822f9358d06baadc02d320a06dfac 617 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 243 479 5.7E-62 T 12-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TSC_c00740 921822f9358d06baadc02d320a06dfac 617 Gene3D G3DSA:3.40.50.920 500 604 3.3E-23 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSC_c00740 921822f9358d06baadc02d320a06dfac 617 SUPERFAMILY SSF53323 4 215 2.75E-17 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 277 291 4.1E-32 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 131 148 4.1E-32 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 213 222 4.1E-32 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 76 85 4.1E-32 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 253 258 4.1E-32 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 PRINTS PR00101 Aspartate carbamoyltransferase signature 38 60 4.1E-32 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 48 55 - T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 Gene3D G3DSA:3.40.50.1370 7 292 3.2E-86 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 SUPERFAMILY SSF53671 1 296 6.55E-89 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 151 294 8.5E-24 T 12-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 296 5.4E-89 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 298 39.251 T 12-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 Gene3D G3DSA:3.40.50.1370 132 275 3.2E-86 T 12-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 145 2.4E-37 T 12-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 261 284 1.2E-17 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 48 67 1.2E-17 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 1.2E-17 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSC_c18310 59fcc9dc8e96b0d4f93260149d72172d 301 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 249 258 1.2E-17 T 12-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 8 371 1.0E-145 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 SUPERFAMILY SSF52317 164 372 6.88E-55 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 SUPERFAMILY SSF52021 7 139 3.53E-55 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 Pfam PF00117 Glutamine amidotransferase class-I 194 367 2.4E-41 T 12-10-2018 IPR017926 Glutamine amidotransferase TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 Gene3D G3DSA:3.50.30.20 5 148 2.5E-56 T 12-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 192 206 2.8E-37 T 12-10-2018 TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 231 245 2.8E-37 T 12-10-2018 TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 303 314 2.8E-37 T 12-10-2018 TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 278 295 2.8E-37 T 12-10-2018 TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 261 277 2.8E-37 T 12-10-2018 TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 SMART SM01097 6 136 4.7E-87 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 Gene3D G3DSA:3.40.50.880 165 374 1.4E-62 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 8 135 1.2E-51 T 12-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 PRINTS PR00096 Glutamine amidotransferase superfamily signature 234 243 3.4E-12 T 12-10-2018 TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 PRINTS PR00096 Glutamine amidotransferase superfamily signature 345 358 3.4E-12 T 12-10-2018 TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 PRINTS PR00096 Glutamine amidotransferase superfamily signature 261 272 3.4E-12 T 12-10-2018 TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 PRINTS PR00097 Anthranilate synthase component II signature 261 272 1.0E-6 T 12-10-2018 TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 PRINTS PR00097 Anthranilate synthase component II signature 234 243 1.0E-6 T 12-10-2018 TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 PRINTS PR00097 Anthranilate synthase component II signature 345 358 1.0E-6 T 12-10-2018 TSC_c02790 b8bb3b46db0a30540f02a1694d5785dc 391 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 6 374 47.682 T 12-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c07800 20dc52ced80f54a7674a97e579225155 211 SUPERFAMILY SSF51419 3 209 3.14E-61 T 12-10-2018 IPR029066 PLP-binding barrel TSC_c07800 20dc52ced80f54a7674a97e579225155 211 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 8 210 2.6E-44 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 TSC_c07800 20dc52ced80f54a7674a97e579225155 211 PIRSF PIRSF004848 3 211 2.4E-55 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 TSC_c07800 20dc52ced80f54a7674a97e579225155 211 Gene3D G3DSA:3.20.20.10 2 211 2.7E-66 T 12-10-2018 IPR029066 PLP-binding barrel TSC_c07800 20dc52ced80f54a7674a97e579225155 211 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 1 211 26.639 T 12-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 TSC_c07800 20dc52ced80f54a7674a97e579225155 211 Pfam PF01168 Alanine racemase, N-terminal domain 15 210 9.1E-20 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSC_c07080 4b1ba99966c421c58f3a219a9aa2bbe7 576 Gene3D G3DSA:3.40.1360.10 229 351 6.8E-26 T 12-10-2018 TSC_c07080 4b1ba99966c421c58f3a219a9aa2bbe7 576 Pfam PF08275 DNA primase catalytic core, N-terminal domain 123 239 2.8E-38 T 12-10-2018 IPR013264 DNA primase, catalytic core, N-terminal TSC_c07080 4b1ba99966c421c58f3a219a9aa2bbe7 576 SUPERFAMILY SSF57783 5 97 7.65E-31 T 12-10-2018 TSC_c07080 4b1ba99966c421c58f3a219a9aa2bbe7 576 TIGRFAM TIGR01391 dnaG: DNA primase 4 382 3.9E-113 T 12-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 TSC_c07080 4b1ba99966c421c58f3a219a9aa2bbe7 576 SMART SM00400 34 88 5.0E-29 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 TSC_c07080 4b1ba99966c421c58f3a219a9aa2bbe7 576 SMART SM00493 246 318 5.6E-11 T 12-10-2018 IPR006171 TOPRIM domain TSC_c07080 4b1ba99966c421c58f3a219a9aa2bbe7 576 PIRSF PIRSF002811 1 576 7.0E-129 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 TSC_c07080 4b1ba99966c421c58f3a219a9aa2bbe7 576 Gene3D G3DSA:3.90.580.10 3 99 1.3E-35 T 12-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 TSC_c07080 4b1ba99966c421c58f3a219a9aa2bbe7 576 Hamap MF_00974 DNA primase [dnaG]. 1 564 25.012 T 12-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 TSC_c07080 4b1ba99966c421c58f3a219a9aa2bbe7 576 Pfam PF01807 CHC2 zinc finger 5 97 7.2E-31 T 12-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 TSC_c07080 4b1ba99966c421c58f3a219a9aa2bbe7 576 SUPERFAMILY SSF56731 107 384 1.05E-77 T 12-10-2018 TSC_c07080 4b1ba99966c421c58f3a219a9aa2bbe7 576 Gene3D G3DSA:3.90.980.10 101 228 2.6E-39 T 12-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily TSC_c07080 4b1ba99966c421c58f3a219a9aa2bbe7 576 Pfam PF13662 Toprim domain 247 312 8.6E-16 T 12-10-2018 IPR006171 TOPRIM domain TSC_c00020 1e817722106c3c335af038d2bf76bbc7 371 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 252 369 5.2E-20 T 12-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 TSC_c00020 1e817722106c3c335af038d2bf76bbc7 371 Gene3D G3DSA:3.10.150.10 131 254 3.4E-28 T 12-10-2018 TSC_c00020 1e817722106c3c335af038d2bf76bbc7 371 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 2 370 1.5E-55 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TSC_c00020 1e817722106c3c335af038d2bf76bbc7 371 Pfam PF02767 DNA polymerase III beta subunit, central domain 134 249 1.1E-17 T 12-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 TSC_c00020 1e817722106c3c335af038d2bf76bbc7 371 Gene3D G3DSA:3.10.150.10 1 120 7.5E-22 T 12-10-2018 TSC_c00020 1e817722106c3c335af038d2bf76bbc7 371 SUPERFAMILY SSF55979 2 114 2.23E-11 T 12-10-2018 TSC_c00020 1e817722106c3c335af038d2bf76bbc7 371 Gene3D G3DSA:3.10.150.10 255 371 3.8E-34 T 12-10-2018 TSC_c00020 1e817722106c3c335af038d2bf76bbc7 371 SUPERFAMILY SSF55979 134 253 9.14E-18 T 12-10-2018 TSC_c00020 1e817722106c3c335af038d2bf76bbc7 371 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 4 116 1.3E-10 T 12-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 TSC_c00020 1e817722106c3c335af038d2bf76bbc7 371 SMART SM00480 17 367 4.2E-63 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TSC_c00020 1e817722106c3c335af038d2bf76bbc7 371 PIRSF PIRSF000804 1 371 6.8E-76 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TSC_c00020 1e817722106c3c335af038d2bf76bbc7 371 SUPERFAMILY SSF55979 251 371 3.77E-23 T 12-10-2018 TSC_c11530 1876eeb0b4a424906a176bcdba9b55d2 324 Gene3D G3DSA:3.10.180.10 150 324 2.5E-43 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c11530 1876eeb0b4a424906a176bcdba9b55d2 324 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 247 268 - T 12-10-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 TSC_c11530 1876eeb0b4a424906a176bcdba9b55d2 324 TIGRFAM TIGR03211 catechol_2_3: catechol 2,3 dioxygenase 6 315 1.7E-102 T 12-10-2018 IPR017624 Catechol 2,3 dioxygenase GO:0008198|GO:0018577|GO:0019439|GO:0055114 KEGG: 00361+1.13.11.2|KEGG: 00362+1.13.11.2|KEGG: 00622+1.13.11.2|KEGG: 00643+1.13.11.2|MetaCyc: PWY-5419|MetaCyc: PWY-5641 TSC_c11530 1876eeb0b4a424906a176bcdba9b55d2 324 Gene3D G3DSA:3.10.180.10 6 141 3.8E-36 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c11530 1876eeb0b4a424906a176bcdba9b55d2 324 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 10 118 4.2E-6 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TSC_c11530 1876eeb0b4a424906a176bcdba9b55d2 324 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 151 269 2.1E-14 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TSC_c11530 1876eeb0b4a424906a176bcdba9b55d2 324 SUPERFAMILY SSF54593 5 270 7.87E-42 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 Gene3D G3DSA:3.50.50.60 141 264 6.5E-134 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 Gene3D G3DSA:3.50.50.60 4 327 6.5E-134 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 SUPERFAMILY SSF55424 339 458 1.01E-41 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 257 273 4.3E-40 T 12-10-2018 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 4.3E-40 T 12-10-2018 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 4.3E-40 T 12-10-2018 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 129 147 4.3E-40 T 12-10-2018 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 286 308 4.3E-40 T 12-10-2018 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 458 1.2E-161 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 PIRSF PIRSF000350 1 458 1.4E-101 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 321 1.7E-70 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 Gene3D G3DSA:3.30.390.30 338 461 3.2E-48 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 339 447 2.0E-36 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 SUPERFAMILY SSF51905 2 331 3.3E-63 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 422 442 1.3E-75 T 12-10-2018 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 400 415 1.3E-75 T 12-10-2018 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 301 308 1.3E-75 T 12-10-2018 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 1.3E-75 T 12-10-2018 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 335 356 1.3E-75 T 12-10-2018 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 132 141 1.3E-75 T 12-10-2018 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.3E-75 T 12-10-2018 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 168 193 1.3E-75 T 12-10-2018 TSC_c02350 ababb6d972bafbb762cac1589b3e71b5 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 258 272 1.3E-75 T 12-10-2018 TSC_c15050 98e60be1a5a56b12266cfc2da186c8bf 818 SUPERFAMILY SSF53756 6 701 4.54E-191 T 12-10-2018 TSC_c15050 98e60be1a5a56b12266cfc2da186c8bf 818 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 101 693 6.0E-235 T 12-10-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TSC_c15050 98e60be1a5a56b12266cfc2da186c8bf 818 Pfam PF11897 Protein of unknown function (DUF3417) 13 113 1.8E-29 T 12-10-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TSC_c15050 98e60be1a5a56b12266cfc2da186c8bf 818 PIRSF PIRSF000460 1 718 3.9E-257 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TSC_c15050 98e60be1a5a56b12266cfc2da186c8bf 818 Pfam PF00343 Carbohydrate phosphorylase 263 609 2.0E-15 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TSC_c15050 98e60be1a5a56b12266cfc2da186c8bf 818 Pfam PF00343 Carbohydrate phosphorylase 118 166 9.2E-5 T 12-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TSC_c15050 98e60be1a5a56b12266cfc2da186c8bf 818 Gene3D G3DSA:3.40.50.2000 259 408 1.7E-11 T 12-10-2018 TSC_c15050 98e60be1a5a56b12266cfc2da186c8bf 818 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 586 598 - T 12-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 TSC_c15050 98e60be1a5a56b12266cfc2da186c8bf 818 Gene3D G3DSA:3.40.50.2000 103 210 2.5E-10 T 12-10-2018 TSC_c15050 98e60be1a5a56b12266cfc2da186c8bf 818 Gene3D G3DSA:3.40.50.2000 409 658 3.3E-37 T 12-10-2018 TSC_c09850 073d62c6329f4fa252353c59ec618247 661 Gene3D G3DSA:1.10.1060.10 249 379 3.9E-17 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSC_c09850 073d62c6329f4fa252353c59ec618247 661 Pfam PF13183 4Fe-4S dicluster domain 281 360 7.7E-12 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c09850 073d62c6329f4fa252353c59ec618247 661 SUPERFAMILY SSF46548 266 373 1.12E-21 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSC_c09850 073d62c6329f4fa252353c59ec618247 661 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 346 357 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c09850 073d62c6329f4fa252353c59ec618247 661 Pfam PF02754 Cysteine-rich domain 425 510 8.9E-18 T 12-10-2018 IPR004017 Cysteine-rich domain TSC_c09850 073d62c6329f4fa252353c59ec618247 661 Pfam PF02754 Cysteine-rich domain 548 635 2.2E-15 T 12-10-2018 IPR004017 Cysteine-rich domain TSC_c06040 aa117eb501a1f507691e54040a1b5e28 181 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 19 160 8.0E-75 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06040 aa117eb501a1f507691e54040a1b5e28 181 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 45 154 7.0E-26 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06040 aa117eb501a1f507691e54040a1b5e28 181 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 126 142 - T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06040 aa117eb501a1f507691e54040a1b5e28 181 SUPERFAMILY SSF56770 17 164 6.28E-68 T 12-10-2018 TSC_c06040 aa117eb501a1f507691e54040a1b5e28 181 Gene3D G3DSA:3.40.50.12280 1 181 2.4E-91 T 12-10-2018 TSC_c06040 aa117eb501a1f507691e54040a1b5e28 181 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 12 159 43.892 T 12-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c02260 bfc492703c03da3e064c25c1e0546b6e 271 SUPERFAMILY SSF51735 3 244 4.03E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c02260 bfc492703c03da3e064c25c1e0546b6e 271 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 128 156 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSC_c02260 bfc492703c03da3e064c25c1e0546b6e 271 Gene3D G3DSA:3.40.50.720 3 261 7.6E-68 T 12-10-2018 TSC_c02260 bfc492703c03da3e064c25c1e0546b6e 271 Pfam PF00106 short chain dehydrogenase 3 185 1.9E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c02260 bfc492703c03da3e064c25c1e0546b6e 271 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 188 0.0028 T 12-10-2018 TSC_c02260 bfc492703c03da3e064c25c1e0546b6e 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 69 80 1.2E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c02260 bfc492703c03da3e064c25c1e0546b6e 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.2E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c02260 bfc492703c03da3e064c25c1e0546b6e 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 1.2E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c02260 bfc492703c03da3e064c25c1e0546b6e 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 1.2E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c02260 bfc492703c03da3e064c25c1e0546b6e 271 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 1.2E-21 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c01300 0ffeb204bb4ec500366fd3cd5d76d570 431 Pfam PF01425 Amidase 17 420 1.0E-94 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSC_c01300 0ffeb204bb4ec500366fd3cd5d76d570 431 ProSitePatterns PS00571 Amidases signature. 142 173 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TSC_c01300 0ffeb204bb4ec500366fd3cd5d76d570 431 Gene3D G3DSA:3.90.1300.10 1 431 5.5E-178 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSC_c01300 0ffeb204bb4ec500366fd3cd5d76d570 431 SUPERFAMILY SSF75304 5 430 7.72E-122 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSC_c11160 a4452f792d2df6659e9a642d6000f210 313 Gene3D G3DSA:3.40.50.10320 44 307 2.7E-56 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TSC_c11160 a4452f792d2df6659e9a642d6000f210 313 Pfam PF02585 GlcNAc-PI de-N-acetylase 50 217 5.1E-29 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TSC_c11160 a4452f792d2df6659e9a642d6000f210 313 SUPERFAMILY SSF102588 47 297 2.22E-47 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TSC_c08450 f4ef853ec15f361f598e799cb820c3ce 258 Pfam PF06182 ABC-2 family transporter protein 59 257 5.8E-21 T 12-10-2018 IPR010390 Protein of unknown function DUF990 TSC_c10040 ee619be3acab694bee90b9aa328c6b62 258 Pfam PF12800 4Fe-4S binding domain 14 28 0.038 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c10040 ee619be3acab694bee90b9aa328c6b62 258 PIRSF PIRSF036298 1 253 3.4E-76 T 12-10-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 TSC_c10040 ee619be3acab694bee90b9aa328c6b62 258 Gene3D G3DSA:3.30.70.20 77 139 3.5E-65 T 12-10-2018 TSC_c10040 ee619be3acab694bee90b9aa328c6b62 258 Gene3D G3DSA:3.30.70.20 5 204 3.5E-65 T 12-10-2018 TSC_c10040 ee619be3acab694bee90b9aa328c6b62 258 SUPERFAMILY SSF54862 1 207 1.26E-70 T 12-10-2018 TSC_c10040 ee619be3acab694bee90b9aa328c6b62 258 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 110 121 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c10040 ee619be3acab694bee90b9aa328c6b62 258 Pfam PF13247 4Fe-4S dicluster domain 72 165 3.1E-28 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c06060 3205bd97245b60e5a42e604d66a9bfe5 272 Gene3D G3DSA:3.40.50.150 3 203 1.7E-68 T 12-10-2018 TSC_c06060 3205bd97245b60e5a42e604d66a9bfe5 272 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 51 78 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 TSC_c06060 3205bd97245b60e5a42e604d66a9bfe5 272 SMART SM00650 36 202 1.6E-66 T 12-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 TSC_c06060 3205bd97245b60e5a42e604d66a9bfe5 272 Gene3D G3DSA:1.10.8.100 205 270 1.1E-23 T 12-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 TSC_c06060 3205bd97245b60e5a42e604d66a9bfe5 272 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 22 267 1.1E-71 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TSC_c06060 3205bd97245b60e5a42e604d66a9bfe5 272 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 20 269 49.358 T 12-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 TSC_c06060 3205bd97245b60e5a42e604d66a9bfe5 272 SUPERFAMILY SSF53335 16 269 5.68E-61 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c06060 3205bd97245b60e5a42e604d66a9bfe5 272 Pfam PF00398 Ribosomal RNA adenine dimethylase 24 242 1.6E-42 T 12-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm TSC_c08990 01d180a05495a73d36d76d065808174a 243 Gene3D G3DSA:3.40.50.720 1 243 3.6E-70 T 12-10-2018 TSC_c08990 01d180a05495a73d36d76d065808174a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 1.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c08990 01d180a05495a73d36d76d065808174a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c08990 01d180a05495a73d36d76d065808174a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 1.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c08990 01d180a05495a73d36d76d065808174a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 1.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c08990 01d180a05495a73d36d76d065808174a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 66 77 1.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c08990 01d180a05495a73d36d76d065808174a 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 1.2E-27 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c08990 01d180a05495a73d36d76d065808174a 243 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 180 0.0032 T 12-10-2018 TSC_c08990 01d180a05495a73d36d76d065808174a 243 SUPERFAMILY SSF51735 3 239 1.99E-61 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c08990 01d180a05495a73d36d76d065808174a 243 Pfam PF00106 short chain dehydrogenase 5 193 4.7E-37 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c08990 01d180a05495a73d36d76d065808174a 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 66 77 5.8E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c08990 01d180a05495a73d36d76d065808174a 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 5.8E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c08990 01d180a05495a73d36d76d065808174a 243 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 5.8E-9 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c08990 01d180a05495a73d36d76d065808174a 243 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSC_c20530 09aafe32cf5f09da4a6cd10ab58414b5 268 SUPERFAMILY SSF51306 27 244 1.26E-45 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TSC_c20530 09aafe32cf5f09da4a6cd10ab58414b5 268 Pfam PF00717 Peptidase S24-like 36 124 3.0E-8 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TSC_c20530 09aafe32cf5f09da4a6cd10ab58414b5 268 Gene3D G3DSA:2.10.109.10 29 242 6.3E-26 T 12-10-2018 TSC_c20530 09aafe32cf5f09da4a6cd10ab58414b5 268 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 19 132 3.5E-21 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TSC_c20530 09aafe32cf5f09da4a6cd10ab58414b5 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 100 112 4.9E-12 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TSC_c20530 09aafe32cf5f09da4a6cd10ab58414b5 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 29 45 4.9E-12 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TSC_c20530 09aafe32cf5f09da4a6cd10ab58414b5 268 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 202 221 4.9E-12 T 12-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 TSC_c20530 09aafe32cf5f09da4a6cd10ab58414b5 268 Gene3D G3DSA:2.170.230.10 111 201 6.3E-26 T 12-10-2018 TSC_c20530 09aafe32cf5f09da4a6cd10ab58414b5 268 ProSitePatterns PS00501 Signal peptidases I serine active site. 38 45 - T 12-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 TSC_c20530 09aafe32cf5f09da4a6cd10ab58414b5 268 ProSitePatterns PS00760 Signal peptidases I lysine active site. 102 114 - T 12-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 TSC_c14000 6e31d7541a4c239c2a95dcdc704ca61c 272 SUPERFAMILY SSF56752 18 214 1.2E-37 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 TSC_c14000 6e31d7541a4c239c2a95dcdc704ca61c 272 Gene3D G3DSA:3.30.470.10 4 102 1.4E-17 T 12-10-2018 TSC_c14000 6e31d7541a4c239c2a95dcdc704ca61c 272 Gene3D G3DSA:3.20.10.10 103 257 1.1E-27 T 12-10-2018 TSC_c14000 6e31d7541a4c239c2a95dcdc704ca61c 272 Pfam PF01063 Amino-transferase class IV 26 212 2.4E-29 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 TSC_c04450 e4bd5abb4d4c27065b8d378a8213129d 319 Gene3D G3DSA:3.20.20.100 3 319 3.4E-113 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSC_c04450 e4bd5abb4d4c27065b8d378a8213129d 319 SUPERFAMILY SSF51430 4 316 5.76E-97 T 12-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily TSC_c04450 e4bd5abb4d4c27065b8d378a8213129d 319 Pfam PF00248 Aldo/keto reductase family 18 315 1.4E-70 T 12-10-2018 IPR023210 NADP-dependent oxidoreductase domain TSC_c04450 e4bd5abb4d4c27065b8d378a8213129d 319 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 258 270 5.5E-10 T 12-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 TSC_c04450 e4bd5abb4d4c27065b8d378a8213129d 319 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 113 123 5.5E-10 T 12-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 TSC_c04450 e4bd5abb4d4c27065b8d378a8213129d 319 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 271 284 5.5E-10 T 12-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 TSC_c04450 e4bd5abb4d4c27065b8d378a8213129d 319 PRINTS PR01577 KCNAB voltage-gated K+ channel beta subunit family signature 164 183 5.5E-10 T 12-10-2018 IPR005399 Potassium channel, voltage-dependent, beta subunit, KCNAB-related Reactome: R-HSA-1296072 TSC_c03100 4b0cd082b8796668ea90e0eee1088a1a 185 SUPERFAMILY SSF109604 10 176 1.76E-23 T 12-10-2018 TSC_c03100 4b0cd082b8796668ea90e0eee1088a1a 185 Pfam PF01966 HD domain 22 127 4.1E-10 T 12-10-2018 IPR006674 HD domain TSC_c03100 4b0cd082b8796668ea90e0eee1088a1a 185 SMART SM00471 18 141 1.6E-7 T 12-10-2018 IPR003607 HD/PDEase domain TSC_c03100 4b0cd082b8796668ea90e0eee1088a1a 185 Gene3D G3DSA:1.10.3210.10 2 183 1.3E-38 T 12-10-2018 TSC_c03100 4b0cd082b8796668ea90e0eee1088a1a 185 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 14 178 3.1E-28 T 12-10-2018 IPR005249 Conserved hypothetical protein CHP00488 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 563 575 2.5E-39 T 12-10-2018 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 149 163 2.5E-39 T 12-10-2018 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 443 454 2.5E-39 T 12-10-2018 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 465 475 2.5E-39 T 12-10-2018 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 539 558 2.5E-39 T 12-10-2018 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 299 313 2.5E-39 T 12-10-2018 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 SUPERFAMILY SSF56784 297 655 1.7E-60 T 12-10-2018 IPR036412 HAD-like superfamily TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 SUPERFAMILY SSF81660 306 445 6.1E-25 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 Pfam PF00690 Cation transporter/ATPase, N-terminus 2 51 4.9E-19 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 Gene3D G3DSA:1.20.1110.10 192 309 2.3E-24 T 12-10-2018 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 Gene3D G3DSA:1.20.1110.10 35 104 9.6E-8 T 12-10-2018 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 SMART SM00831 2 57 2.9E-16 T 12-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 Gene3D G3DSA:1.20.1110.10 551 809 2.0E-53 T 12-10-2018 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 Gene3D G3DSA:2.60.120.1500 105 191 6.0E-31 T 12-10-2018 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 71 493 1.0E-70 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 510 624 6.5E-36 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 Pfam PF00689 Cation transporting ATPase, C-terminus 635 801 6.5E-33 T 12-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 539 555 1.1E-20 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 511 527 1.1E-20 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 571 596 1.1E-20 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 411 429 1.1E-20 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 Pfam PF00122 E1-E2 ATPase 99 279 4.6E-56 T 12-10-2018 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 SUPERFAMILY SSF81665 2 807 4.32E-100 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 Gene3D G3DSA:3.40.1110.10 310 443 4.5E-21 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 Gene3D G3DSA:3.40.50.1000 444 502 2.9E-11 T 12-10-2018 IPR023214 HAD superfamily TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 Pfam PF00702 haloacid dehalogenase-like hydrolase 296 553 8.9E-29 T 12-10-2018 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 SUPERFAMILY SSF81653 102 198 4.45E-32 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TSC_c09600 82cf8aa9d7668123c7bde665ad64f842 812 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 301 307 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TSC_c17230 3f60358803f6bcc824a5f430bb0d3a8b 307 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 201 222 - T 12-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 TSC_c17230 3f60358803f6bcc824a5f430bb0d3a8b 307 SUPERFAMILY SSF54534 169 263 1.7E-26 T 12-10-2018 TSC_c17230 3f60358803f6bcc824a5f430bb0d3a8b 307 SUPERFAMILY SSF109998 23 202 2.86E-19 T 12-10-2018 IPR027304 Trigger factor/SurA domain superfamily TSC_c17230 3f60358803f6bcc824a5f430bb0d3a8b 307 Pfam PF00639 PPIC-type PPIASE domain 186 261 9.0E-20 T 12-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 TSC_c17230 3f60358803f6bcc824a5f430bb0d3a8b 307 Gene3D G3DSA:1.10.4030.30 21 176 1.4E-8 T 12-10-2018 TSC_c17230 3f60358803f6bcc824a5f430bb0d3a8b 307 Gene3D G3DSA:3.10.50.40 177 260 6.0E-27 T 12-10-2018 TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 Pfam PF00270 DEAD/DEAH box helicase 446 603 4.1E-16 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 SUPERFAMILY SSF52540 378 625 1.1E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 SMART SM01058 320 417 1.7E-37 T 12-10-2018 IPR003711 CarD-like/TRCF domain TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 Pfam PF02559 CarD-like/TRCF domain 321 413 3.5E-24 T 12-10-2018 IPR003711 CarD-like/TRCF domain TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 SUPERFAMILY SSF143517 827 931 1.57E-25 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 Gene3D G3DSA:3.40.50.300 383 622 1.5E-209 T 12-10-2018 TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 16 943 24.526 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 SMART SM00490 667 751 2.3E-15 T 12-10-2018 IPR001650 Helicase, C-terminal TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 Gene3D G3DSA:3.40.50.300 321 829 1.5E-209 T 12-10-2018 TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 Gene3D G3DSA:3.90.1150.50 838 956 1.4E-21 T 12-10-2018 IPR037235 TRCF-like, C-terminal domain TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 SUPERFAMILY SSF141259 316 389 1.57E-19 T 12-10-2018 IPR036101 CarD-like/TRCF domain superfamily TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 SMART SM00982 842 940 9.9E-27 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 Pfam PF03461 TRCF domain 843 927 6.4E-22 T 12-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 SUPERFAMILY SSF52540 623 829 3.19E-38 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 SUPERFAMILY SSF52540 19 140 3.32E-6 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 Gene3D G3DSA:2.30.30.840 324 382 1.5E-209 T 12-10-2018 TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 316 915 3.2E-255 T 12-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 Pfam PF00271 Helicase conserved C-terminal domain 649 750 6.8E-13 T 12-10-2018 IPR001650 Helicase, C-terminal TSC_c13230 bde1de30fb8c78a7db98393a011624be 980 SMART SM00487 441 631 3.3E-36 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSC_c19170 7807d7d00b6f3e6e699880e6ff8bc4ec 617 SMART SM00382 197 336 2.9E-25 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c19170 7807d7d00b6f3e6e699880e6ff8bc4ec 617 Pfam PF01434 Peptidase family M41 396 602 7.8E-69 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 TSC_c19170 7807d7d00b6f3e6e699880e6ff8bc4ec 617 SUPERFAMILY SSF140990 416 607 4.45E-64 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 TSC_c19170 7807d7d00b6f3e6e699880e6ff8bc4ec 617 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 201 333 7.1E-45 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSC_c19170 7807d7d00b6f3e6e699880e6ff8bc4ec 617 Gene3D G3DSA:1.10.8.60 335 412 8.6E-27 T 12-10-2018 TSC_c19170 7807d7d00b6f3e6e699880e6ff8bc4ec 617 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 114 603 1.1E-216 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 TSC_c19170 7807d7d00b6f3e6e699880e6ff8bc4ec 617 Gene3D G3DSA:1.20.58.760 416 616 1.1E-70 T 12-10-2018 TSC_c19170 7807d7d00b6f3e6e699880e6ff8bc4ec 617 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 6 616 35.275 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 TSC_c19170 7807d7d00b6f3e6e699880e6ff8bc4ec 617 SUPERFAMILY SSF52540 157 405 2.26E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c19170 7807d7d00b6f3e6e699880e6ff8bc4ec 617 Pfam PF06480 FtsH Extracellular 8 69 4.3E-6 T 12-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 TSC_c19170 7807d7d00b6f3e6e699880e6ff8bc4ec 617 ProSitePatterns PS00674 AAA-protein family signature. 304 322 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TSC_c19170 7807d7d00b6f3e6e699880e6ff8bc4ec 617 Gene3D G3DSA:3.40.50.300 151 333 2.0E-69 T 12-10-2018 TSC_c02990 a6436627ff481dcbf44e187399e6a01f 210 Gene3D G3DSA:2.160.10.10 84 209 1.2E-30 T 12-10-2018 TSC_c02990 a6436627ff481dcbf44e187399e6a01f 210 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 2 200 5.0E-70 T 12-10-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like TSC_c02990 a6436627ff481dcbf44e187399e6a01f 210 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 152 185 7.8E-5 T 12-10-2018 IPR001451 Hexapeptide repeat TSC_c02990 a6436627ff481dcbf44e187399e6a01f 210 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 151 3.7E-5 T 12-10-2018 IPR001451 Hexapeptide repeat TSC_c02990 a6436627ff481dcbf44e187399e6a01f 210 Gene3D G3DSA:3.40.50.20 1 83 1.1E-16 T 12-10-2018 TSC_c02990 a6436627ff481dcbf44e187399e6a01f 210 SUPERFAMILY SSF51161 2 206 7.76E-43 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily TSC_c23910 aa326292c923f6057ac663e3488bd6ef 356 SUPERFAMILY SSF53187 3 354 2.6E-49 T 12-10-2018 TSC_c23910 aa326292c923f6057ac663e3488bd6ef 356 Pfam PF07687 Peptidase dimerisation domain 157 247 2.9E-9 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain TSC_c23910 aa326292c923f6057ac663e3488bd6ef 356 Pfam PF01546 Peptidase family M20/M25/M40 59 350 2.5E-27 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 TSC_c23910 aa326292c923f6057ac663e3488bd6ef 356 SUPERFAMILY SSF55031 162 252 2.39E-11 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSC_c23910 aa326292c923f6057ac663e3488bd6ef 356 Gene3D G3DSA:3.30.70.360 159 273 3.1E-73 T 12-10-2018 TSC_c23910 aa326292c923f6057ac663e3488bd6ef 356 Gene3D G3DSA:3.40.630.10 12 341 3.1E-73 T 12-10-2018 TSC_c02500 d32a84b3b4a5cd8ea40dbc153665b60e 351 Pfam PF00924 Mechanosensitive ion channel 134 332 1.6E-43 T 12-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 TSC_c02500 d32a84b3b4a5cd8ea40dbc153665b60e 351 SUPERFAMILY SSF50182 174 236 5.56E-14 T 12-10-2018 IPR010920 LSM domain superfamily TSC_c02500 d32a84b3b4a5cd8ea40dbc153665b60e 351 SUPERFAMILY SSF82689 239 343 1.57E-24 T 12-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 TSC_c02500 d32a84b3b4a5cd8ea40dbc153665b60e 351 SUPERFAMILY SSF82861 92 173 2.48E-10 T 12-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 TSC_c02500 d32a84b3b4a5cd8ea40dbc153665b60e 351 Gene3D G3DSA:2.30.30.60 190 239 9.5E-17 T 12-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily TSC_c02500 d32a84b3b4a5cd8ea40dbc153665b60e 351 Gene3D G3DSA:3.30.70.100 241 330 8.2E-32 T 12-10-2018 TSC_c10890 48ab8ba9ece840a4f2fbc9e7de68e1b9 433 SUPERFAMILY SSF55874 312 423 3.93E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c10890 48ab8ba9ece840a4f2fbc9e7de68e1b9 433 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 325 422 4.4E-14 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c10890 48ab8ba9ece840a4f2fbc9e7de68e1b9 433 Pfam PF00512 His Kinase A (phospho-acceptor) domain 208 266 2.3E-7 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c10890 48ab8ba9ece840a4f2fbc9e7de68e1b9 433 Pfam PF00672 HAMP domain 153 199 9.5E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSC_c10890 48ab8ba9ece840a4f2fbc9e7de68e1b9 433 SUPERFAMILY SSF47384 187 265 3.14E-10 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSC_c10890 48ab8ba9ece840a4f2fbc9e7de68e1b9 433 SMART SM00304 151 203 1.3E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSC_c10890 48ab8ba9ece840a4f2fbc9e7de68e1b9 433 SMART SM00388 204 267 1.1E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c10890 48ab8ba9ece840a4f2fbc9e7de68e1b9 433 Gene3D G3DSA:1.10.287.130 155 267 1.7E-16 T 12-10-2018 TSC_c10890 48ab8ba9ece840a4f2fbc9e7de68e1b9 433 SMART SM00387 320 425 1.4E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c10890 48ab8ba9ece840a4f2fbc9e7de68e1b9 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 386 404 9.9E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c10890 48ab8ba9ece840a4f2fbc9e7de68e1b9 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 369 9.9E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c10890 48ab8ba9ece840a4f2fbc9e7de68e1b9 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 422 9.9E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c10890 48ab8ba9ece840a4f2fbc9e7de68e1b9 433 Gene3D G3DSA:3.30.565.10 307 426 6.9E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c24520 944f0dcd8f705b46624e23f3345bb7d1 385 Gene3D G3DSA:3.90.1150.10 24 377 3.9E-159 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c24520 944f0dcd8f705b46624e23f3345bb7d1 385 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 231 244 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TSC_c24520 944f0dcd8f705b46624e23f3345bb7d1 385 SUPERFAMILY SSF53383 6 383 7.37E-118 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c24520 944f0dcd8f705b46624e23f3345bb7d1 385 Pfam PF00155 Aminotransferase class I and II 32 378 7.8E-77 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSC_c24520 944f0dcd8f705b46624e23f3345bb7d1 385 Gene3D G3DSA:3.40.640.10 63 281 3.9E-159 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c13280 f52f6e69f78b6289144351b08911c0d8 403 Gene3D G3DSA:3.40.50.2000 191 357 1.6E-40 T 12-10-2018 TSC_c13280 f52f6e69f78b6289144351b08911c0d8 403 Pfam PF13439 Glycosyltransferase Family 4 18 179 1.2E-30 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSC_c13280 f52f6e69f78b6289144351b08911c0d8 403 Gene3D G3DSA:3.40.50.2000 5 187 7.7E-35 T 12-10-2018 TSC_c13280 f52f6e69f78b6289144351b08911c0d8 403 Pfam PF00534 Glycosyl transferases group 1 192 352 2.6E-38 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TSC_c13280 f52f6e69f78b6289144351b08911c0d8 403 SUPERFAMILY SSF53756 8 373 2.6E-77 T 12-10-2018 TSC_c07660 fb6ad8f677d583f8bd38529095137422 167 SUPERFAMILY SSF58113 15 140 6.8E-12 T 12-10-2018 TSC_c07660 fb6ad8f677d583f8bd38529095137422 167 Gene3D G3DSA:1.20.120.20 9 157 1.9E-14 T 12-10-2018 TSC_c17550 13cb7d708a230920a165abb097411f8e 90 PRINTS PR00354 7Fe ferredoxin signature 23 33 5.8E-15 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSC_c17550 13cb7d708a230920a165abb097411f8e 90 PRINTS PR00354 7Fe ferredoxin signature 39 56 5.8E-15 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSC_c17550 13cb7d708a230920a165abb097411f8e 90 PRINTS PR00354 7Fe ferredoxin signature 13 23 5.8E-15 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSC_c17550 13cb7d708a230920a165abb097411f8e 90 Gene3D G3DSA:3.30.70.20 6 89 1.5E-32 T 12-10-2018 TSC_c17550 13cb7d708a230920a165abb097411f8e 90 SUPERFAMILY SSF54862 5 85 1.21E-19 T 12-10-2018 TSC_c17550 13cb7d708a230920a165abb097411f8e 90 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 44 55 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c17550 13cb7d708a230920a165abb097411f8e 90 Pfam PF00037 4Fe-4S binding domain 38 59 6.4E-10 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c00640 22f7bbf8d5221f9fc7958ba6c956d67c 198 TIGRFAM TIGR00444 mazG: MazG family protein 10 151 2.2E-48 T 12-10-2018 IPR011551 NTP pyrophosphohydrolase MazG TSC_c00640 22f7bbf8d5221f9fc7958ba6c956d67c 198 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 26 99 3.7E-27 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TSC_c00640 22f7bbf8d5221f9fc7958ba6c956d67c 198 SUPERFAMILY SSF101386 3 103 2.78E-24 T 12-10-2018 TSC_c00640 22f7bbf8d5221f9fc7958ba6c956d67c 198 Gene3D G3DSA:1.10.287.1080 1 123 1.7E-45 T 12-10-2018 TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 Gene3D G3DSA:3.30.300.10 384 503 2.5E-51 T 12-10-2018 TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 SUPERFAMILY SSF52317 1 219 2.29E-55 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 Pfam PF00117 Glutamine amidotransferase class-I 4 181 1.0E-39 T 12-10-2018 IPR017926 Glutamine amidotransferase TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 Pfam PF00958 GMP synthase C terminal domain 413 502 3.4E-38 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 SUPERFAMILY SSF54810 383 503 2.48E-49 T 12-10-2018 TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 PRINTS PR00096 Glutamine amidotransferase superfamily signature 160 173 1.9E-7 T 12-10-2018 TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 1.9E-7 T 12-10-2018 TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 1.9E-7 T 12-10-2018 TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 Gene3D G3DSA:3.40.50.880 1 188 3.7E-56 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 PRINTS PR00097 Anthranilate synthase component II signature 73 84 6.2E-5 T 12-10-2018 TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 PRINTS PR00097 Anthranilate synthase component II signature 160 173 6.2E-5 T 12-10-2018 TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 PRINTS PR00097 Anthranilate synthase component II signature 46 55 6.2E-5 T 12-10-2018 TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 SUPERFAMILY SSF52402 180 424 8.82E-50 T 12-10-2018 TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 Pfam PF01171 PP-loop family 212 252 1.7E-4 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 Gene3D G3DSA:3.40.50.620 191 383 4.7E-66 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 185 1.2E-66 T 12-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 195 503 2.3E-133 T 12-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 TSC_c19340 8caf4c5bc5f23ff5b2f9cd21a8175e3d 503 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 1 503 50.966 T 12-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 TSC_c14210 dd99c2e00c03b20cceb52be3443b6d7a 443 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 47 104 1.1E-4 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c14210 dd99c2e00c03b20cceb52be3443b6d7a 443 Gene3D G3DSA:1.10.645.20 101 442 1.9E-80 T 12-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c14210 dd99c2e00c03b20cceb52be3443b6d7a 443 SUPERFAMILY SSF56762 110 442 3.01E-76 T 12-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c14210 dd99c2e00c03b20cceb52be3443b6d7a 443 SUPERFAMILY SSF143243 43 114 1.96E-10 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c14210 dd99c2e00c03b20cceb52be3443b6d7a 443 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 221 366 1.8E-18 T 12-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c20110 35e983bdcf60924b926182ae38bd0f84 406 Pfam PF01676 Metalloenzyme superfamily 17 394 1.1E-33 T 12-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 TSC_c20110 35e983bdcf60924b926182ae38bd0f84 406 Gene3D G3DSA:3.30.70.2130 92 233 3.2E-97 T 12-10-2018 TSC_c20110 35e983bdcf60924b926182ae38bd0f84 406 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 19 395 3.8E-86 T 12-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSC_c20110 35e983bdcf60924b926182ae38bd0f84 406 Hamap MF_01402_B 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 16 397 59.886 T 12-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSC_c20110 35e983bdcf60924b926182ae38bd0f84 406 PIRSF PIRSF006392 13 402 9.9E-125 T 12-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSC_c20110 35e983bdcf60924b926182ae38bd0f84 406 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 51 220 1.1E-46 T 12-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSC_c20110 35e983bdcf60924b926182ae38bd0f84 406 Gene3D G3DSA:3.40.720.10 19 392 3.2E-97 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TSC_c20110 35e983bdcf60924b926182ae38bd0f84 406 SUPERFAMILY SSF53649 17 370 3.53E-32 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TSC_c10250 70df31151fe1face9c91068de8209dab 128 SUPERFAMILY SSF89095 1 125 2.3E-15 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 TSC_c10250 70df31151fe1face9c91068de8209dab 128 Gene3D G3DSA:1.10.1510.10 1 66 2.5E-6 T 12-10-2018 TSC_c10250 70df31151fe1face9c91068de8209dab 128 Pfam PF09424 Yqey-like protein 61 117 8.0E-6 T 12-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 TSC_c10250 70df31151fe1face9c91068de8209dab 128 Pfam PF09424 Yqey-like protein 5 52 2.1E-4 T 12-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 TSC_c24600 b943f33473210088ad0dd719d9e82ed9 442 TIGRFAM TIGR00836 amt: ammonium transporter 26 417 5.6E-127 T 12-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 TSC_c24600 b943f33473210088ad0dd719d9e82ed9 442 ProSitePatterns PS01219 Ammonium transporters signature. 174 199 - T 12-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 TSC_c24600 b943f33473210088ad0dd719d9e82ed9 442 Gene3D G3DSA:1.10.3430.10 12 424 5.3E-133 T 12-10-2018 IPR029020 Ammonium/urea transporter TSC_c24600 b943f33473210088ad0dd719d9e82ed9 442 SUPERFAMILY SSF111352 22 397 9.42E-118 T 12-10-2018 TSC_c24600 b943f33473210088ad0dd719d9e82ed9 442 Pfam PF00909 Ammonium Transporter Family 27 417 3.7E-115 T 12-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 TSC_c00880 ae184bde5e4945f09c8017a34a7dde6e 765 SUPERFAMILY SSF52210 327 467 1.27E-30 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSC_c00880 ae184bde5e4945f09c8017a34a7dde6e 765 Gene3D G3DSA:3.30.470.20 613 736 4.9E-6 T 12-10-2018 TSC_c00880 ae184bde5e4945f09c8017a34a7dde6e 765 Gene3D G3DSA:3.40.50.720 198 324 1.5E-31 T 12-10-2018 TSC_c00880 ae184bde5e4945f09c8017a34a7dde6e 765 Gene3D G3DSA:3.40.50.261 326 469 1.8E-37 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSC_c00880 ae184bde5e4945f09c8017a34a7dde6e 765 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 347 466 5.5E-33 T 12-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain TSC_c00880 ae184bde5e4945f09c8017a34a7dde6e 765 Pfam PF00583 Acetyltransferase (GNAT) family 75 160 1.2E-7 T 12-10-2018 IPR000182 GNAT domain TSC_c00880 ae184bde5e4945f09c8017a34a7dde6e 765 SMART SM00881 202 301 6.8E-26 T 12-10-2018 IPR003781 CoA-binding GO:0048037 TSC_c00880 ae184bde5e4945f09c8017a34a7dde6e 765 Gene3D G3DSA:3.40.50.261 502 604 2.7E-8 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSC_c00880 ae184bde5e4945f09c8017a34a7dde6e 765 SUPERFAMILY SSF51735 194 332 1.67E-26 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c00880 ae184bde5e4945f09c8017a34a7dde6e 765 Gene3D G3DSA:3.40.630.30 17 197 3.1E-37 T 12-10-2018 TSC_c00880 ae184bde5e4945f09c8017a34a7dde6e 765 SUPERFAMILY SSF55729 25 166 3.31E-20 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSC_c00880 ae184bde5e4945f09c8017a34a7dde6e 765 Pfam PF13380 CoA binding domain 208 330 1.6E-16 T 12-10-2018 IPR003781 CoA-binding GO:0048037 TSC_c00880 ae184bde5e4945f09c8017a34a7dde6e 765 SUPERFAMILY SSF52210 472 599 1.96E-9 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSC_c07470 7a0566889279ab301235163b5e3d0684 514 Pfam PF01642 Methylmalonyl-CoA mutase 17 508 7.0E-218 T 12-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSC_c07470 7a0566889279ab301235163b5e3d0684 514 SUPERFAMILY SSF51703 14 510 1.65E-208 T 12-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSC_c07470 7a0566889279ab301235163b5e3d0684 514 Gene3D G3DSA:3.20.20.240 5 514 2.4E-235 T 12-10-2018 TSC_c07470 7a0566889279ab301235163b5e3d0684 514 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 13 511 3.4E-230 T 12-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSC_c11070 6eb012fcd1602596ab7785b84efa2d76 416 SUPERFAMILY SSF47384 196 276 1.16E-11 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSC_c11070 6eb012fcd1602596ab7785b84efa2d76 416 SUPERFAMILY SSF55874 276 406 7.86E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c11070 6eb012fcd1602596ab7785b84efa2d76 416 SMART SM00388 213 276 4.9E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c11070 6eb012fcd1602596ab7785b84efa2d76 416 Gene3D G3DSA:1.10.287.130 169 277 2.3E-19 T 12-10-2018 TSC_c11070 6eb012fcd1602596ab7785b84efa2d76 416 Pfam PF00512 His Kinase A (phospho-acceptor) domain 215 275 2.8E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c11070 6eb012fcd1602596ab7785b84efa2d76 416 SMART SM00387 318 406 4.4E-13 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c11070 6eb012fcd1602596ab7785b84efa2d76 416 Pfam PF00672 HAMP domain 167 208 2.6E-6 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSC_c11070 6eb012fcd1602596ab7785b84efa2d76 416 Gene3D G3DSA:3.30.565.10 295 403 3.1E-15 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c04460 ad268d4ce8f82d22f6de0b06ca41702e 64 SMART SM00704 18 54 1.4E-9 T 12-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 TSC_c04460 ad268d4ce8f82d22f6de0b06ca41702e 64 Gene3D G3DSA:3.40.5.90 1 62 7.3E-19 T 12-10-2018 TSC_c04460 ad268d4ce8f82d22f6de0b06ca41702e 64 Pfam PF09360 Iron-binding zinc finger CDGSH type 5 49 2.4E-16 T 12-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 TSC_c06880 87cc417a718927b70abef41021d20a22 349 Gene3D G3DSA:3.30.70.1400 50 136 4.4E-90 T 12-10-2018 TSC_c06880 87cc417a718927b70abef41021d20a22 349 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 2 346 1.2E-105 T 12-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TSC_c06880 87cc417a718927b70abef41021d20a22 349 Pfam PF01571 Aminomethyltransferase folate-binding domain 6 253 5.5E-91 T 12-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain TSC_c06880 87cc417a718927b70abef41021d20a22 349 PIRSF PIRSF006487 1 349 4.7E-82 T 12-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 TSC_c06880 87cc417a718927b70abef41021d20a22 349 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 258 339 4.2E-16 T 12-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TSC_c06880 87cc417a718927b70abef41021d20a22 349 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 348 39.754 T 12-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 TSC_c06880 87cc417a718927b70abef41021d20a22 349 SUPERFAMILY SSF103025 1 268 1.88E-97 T 12-10-2018 TSC_c06880 87cc417a718927b70abef41021d20a22 349 SUPERFAMILY SSF101790 267 347 1.37E-19 T 12-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal TSC_c06880 87cc417a718927b70abef41021d20a22 349 Gene3D G3DSA:2.40.30.110 271 347 1.3E-19 T 12-10-2018 TSC_c06880 87cc417a718927b70abef41021d20a22 349 Gene3D G3DSA:3.30.1360.120 3 230 4.4E-90 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TSC_c06880 87cc417a718927b70abef41021d20a22 349 Gene3D G3DSA:4.10.1250.10 232 269 2.7E-10 T 12-10-2018 TSC_c14580 54b39b3d5de1014b0ac563317d594be9 209 Pfam PF00072 Response regulator receiver domain 4 115 1.3E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c14580 54b39b3d5de1014b0ac563317d594be9 209 SUPERFAMILY SSF52172 2 129 1.71E-29 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c14580 54b39b3d5de1014b0ac563317d594be9 209 SUPERFAMILY SSF46894 134 207 2.86E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSC_c14580 54b39b3d5de1014b0ac563317d594be9 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 5.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c14580 54b39b3d5de1014b0ac563317d594be9 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 5.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c14580 54b39b3d5de1014b0ac563317d594be9 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 5.9E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c14580 54b39b3d5de1014b0ac563317d594be9 209 SMART SM00421 144 201 3.7E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c14580 54b39b3d5de1014b0ac563317d594be9 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 201 5.0E-20 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c14580 54b39b3d5de1014b0ac563317d594be9 209 Gene3D G3DSA:3.40.50.12740 2 207 7.8E-62 T 12-10-2018 TSC_c14580 54b39b3d5de1014b0ac563317d594be9 209 SMART SM00448 2 115 9.0E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 SUPERFAMILY SSF55271 9 117 2.22E-35 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 654 670 - T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 Gene3D G3DSA:1.10.1420.10 372 507 2.7E-97 T 12-10-2018 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 SMART SM00533 264 561 1.8E-100 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 PIRSF PIRSF037677 9 186 3.5E-26 T 12-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 PIRSF PIRSF037677 218 775 1.3E-114 T 12-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 Gene3D G3DSA:3.40.50.300 539 762 1.2E-99 T 12-10-2018 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 10 790 21.963 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 Gene3D G3DSA:3.30.420.110 128 245 7.8E-43 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 11 795 0.0 T 12-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 Gene3D G3DSA:3.40.1170.10 1 123 1.4E-45 T 12-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 Pfam PF01624 MutS domain I 12 121 4.8E-35 T 12-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 Pfam PF05192 MutS domain III 252 531 2.5E-38 T 12-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 SUPERFAMILY SSF52540 539 757 6.26E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 SMART SM00534 573 757 6.0E-117 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 SUPERFAMILY SSF48334 266 537 5.75E-77 T 12-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 Pfam PF00488 MutS domain V 577 759 4.0E-79 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 Pfam PF05188 MutS domain II 129 186 4.0E-9 T 12-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 Gene3D G3DSA:1.10.1420.10 255 534 2.7E-97 T 12-10-2018 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 SUPERFAMILY SSF53150 122 262 1.44E-25 T 12-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 TSC_c05150 f9b7e25aa5d11f9d3b61d47d7d46b87e 808 Pfam PF05190 MutS family domain IV 400 489 5.9E-26 T 12-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 6 815 2.3E-299 T 12-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 Pfam PF14890 Intein splicing domain 827 1239 2.6E-30 T 12-10-2018 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 SMART SM00306 813 913 1.5E-20 T 12-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 SUPERFAMILY SSF47781 1315 1349 7.34E-5 T 12-10-2018 IPR010994 RuvA domain 2-like TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 Gene3D G3DSA:1.10.150.870 1252 1366 8.2E-9 T 12-10-2018 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 SUPERFAMILY SSF55608 1015 1115 1.25E-10 T 12-10-2018 IPR027434 Homing endonuclease TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 SUPERFAMILY SSF89550 5 259 7.65E-29 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 815 893 4.3E-9 T 12-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 SMART SM00481 7 76 9.5E-25 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 Pfam PF14579 Helix-hairpin-helix motif 1289 1375 5.7E-29 T 12-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 SMART SM00305 1200 1245 1.1E-11 T 12-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 Gene3D G3DSA:1.10.10.1600 495 570 4.3E-28 T 12-10-2018 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 1218 1240 1.3E-7 T 12-10-2018 IPR030934 Intein C-terminal splicing region TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 Gene3D G3DSA:3.10.28.10 931 1091 1.2E-21 T 12-10-2018 IPR027434 Homing endonuclease TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 Gene3D G3DSA:2.170.16.10 1154 1239 1.1E-14 T 12-10-2018 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 Pfam PF02811 PHP domain 8 183 1.4E-47 T 12-10-2018 IPR004013 PHP domain GO:0003824 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 377 790 3.9E-166 T 12-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 Pfam PF01336 OB-fold nucleic acid binding domain 1469 1541 7.8E-7 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 PRINTS PR00379 Intein signature 880 893 6.9E-19 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 PRINTS PR00379 Intein signature 1216 1233 6.9E-19 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 PRINTS PR00379 Intein signature 1028 1040 6.9E-19 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 PRINTS PR00379 Intein signature 927 939 6.9E-19 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 PRINTS PR00379 Intein signature 1234 1243 6.9E-19 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 PRINTS PR00379 Intein signature 1056 1071 6.9E-19 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 Pfam PF14528 LAGLIDADG-like domain 1029 1106 5.6E-9 T 12-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 SUPERFAMILY SSF51294 814 1239 3.34E-44 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 Gene3D G3DSA:2.170.16.10 813 930 3.3E-25 T 12-10-2018 TSC_c00790 90358e51ddbb4ea010f32d9b340c6040 1646 Gene3D G3DSA:3.20.20.140 2 283 8.3E-107 T 12-10-2018 TSC_c09010 59fc8f09a1bd34ee2cb7be57c3c5f577 249 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 248 1.9E-96 T 12-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 TSC_c09010 59fc8f09a1bd34ee2cb7be57c3c5f577 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 247 1.4E-56 T 12-10-2018 TSC_c09010 59fc8f09a1bd34ee2cb7be57c3c5f577 249 SUPERFAMILY SSF51735 4 248 9.12E-74 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c09010 59fc8f09a1bd34ee2cb7be57c3c5f577 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09010 59fc8f09a1bd34ee2cb7be57c3c5f577 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09010 59fc8f09a1bd34ee2cb7be57c3c5f577 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09010 59fc8f09a1bd34ee2cb7be57c3c5f577 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09010 59fc8f09a1bd34ee2cb7be57c3c5f577 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09010 59fc8f09a1bd34ee2cb7be57c3c5f577 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.4E-38 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09010 59fc8f09a1bd34ee2cb7be57c3c5f577 249 Gene3D G3DSA:3.40.50.720 3 249 1.3E-76 T 12-10-2018 TSC_c09010 59fc8f09a1bd34ee2cb7be57c3c5f577 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 1.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09010 59fc8f09a1bd34ee2cb7be57c3c5f577 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 124 132 1.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09010 59fc8f09a1bd34ee2cb7be57c3c5f577 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 1.2E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c18980 ed652b12039996b0e55ab419dedb8143 131 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 16 115 4.1E-16 T 12-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c18980 ed652b12039996b0e55ab419dedb8143 131 Gene3D G3DSA:1.20.1300.10 12 125 7.4E-22 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c18980 ed652b12039996b0e55ab419dedb8143 131 SUPERFAMILY SSF81343 17 126 1.92E-24 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c24880 fee526e30b63974fa512d8c63423607c 708 Gene3D G3DSA:1.10.8.630 2 109 3.0E-12 T 12-10-2018 TSC_c24880 fee526e30b63974fa512d8c63423607c 708 Hamap MF_00983 Probable primosomal protein N' [priA]. 5 702 16.872 T 12-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 TSC_c11770 9d445d989df968e29ab49e77d5ce6116 216 Pfam PF10414 Sirohaem synthase dimerisation region 151 188 4.9E-5 T 12-10-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TSC_c11770 9d445d989df968e29ab49e77d5ce6116 216 Gene3D G3DSA:3.30.160.110 113 147 1.1E-9 T 12-10-2018 TSC_c11770 9d445d989df968e29ab49e77d5ce6116 216 SUPERFAMILY SSF75615 114 188 1.05E-17 T 12-10-2018 TSC_c11770 9d445d989df968e29ab49e77d5ce6116 216 Pfam PF13241 Putative NAD(P)-binding 6 115 8.8E-16 T 12-10-2018 TSC_c11770 9d445d989df968e29ab49e77d5ce6116 216 Gene3D G3DSA:3.40.50.720 1 110 1.9E-21 T 12-10-2018 TSC_c11770 9d445d989df968e29ab49e77d5ce6116 216 SUPERFAMILY SSF51735 1 108 1.67E-15 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c11770 9d445d989df968e29ab49e77d5ce6116 216 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 189 6.9E-39 T 12-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TSC_c05900 20a3b0d9447552cc30c75d474296dda7 327 Pfam PF00491 Arginase family 37 322 6.8E-80 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 TSC_c05900 20a3b0d9447552cc30c75d474296dda7 327 Gene3D G3DSA:3.40.800.10 36 327 4.0E-119 T 12-10-2018 TSC_c05900 20a3b0d9447552cc30c75d474296dda7 327 PRINTS PR00116 Arginase signature 202 220 4.7E-33 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 TSC_c05900 20a3b0d9447552cc30c75d474296dda7 327 PRINTS PR00116 Arginase signature 284 298 4.7E-33 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 TSC_c05900 20a3b0d9447552cc30c75d474296dda7 327 PRINTS PR00116 Arginase signature 249 278 4.7E-33 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 TSC_c05900 20a3b0d9447552cc30c75d474296dda7 327 PRINTS PR00116 Arginase signature 130 145 4.7E-33 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 TSC_c05900 20a3b0d9447552cc30c75d474296dda7 327 TIGRFAM TIGR01229 rocF_arginase: arginase 40 325 3.0E-90 T 12-10-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 TSC_c05900 20a3b0d9447552cc30c75d474296dda7 327 PIRSF PIRSF036979 16 322 8.7E-39 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 TSC_c05900 20a3b0d9447552cc30c75d474296dda7 327 SUPERFAMILY SSF52768 37 325 6.3E-92 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily TSC_c17980 6a356bfbb19d0b34f3af1bf3f786a4ee 502 Pfam PF00005 ABC transporter 274 429 1.1E-14 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c17980 6a356bfbb19d0b34f3af1bf3f786a4ee 502 Gene3D G3DSA:3.40.50.300 260 500 1.0E-39 T 12-10-2018 TSC_c17980 6a356bfbb19d0b34f3af1bf3f786a4ee 502 SMART SM00382 283 478 15.0 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c17980 6a356bfbb19d0b34f3af1bf3f786a4ee 502 SMART SM00382 35 223 1.2E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c17980 6a356bfbb19d0b34f3af1bf3f786a4ee 502 SUPERFAMILY SSF52540 271 490 3.22E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c17980 6a356bfbb19d0b34f3af1bf3f786a4ee 502 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c17980 6a356bfbb19d0b34f3af1bf3f786a4ee 502 SUPERFAMILY SSF52540 11 230 3.59E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c17980 6a356bfbb19d0b34f3af1bf3f786a4ee 502 Pfam PF00005 ABC transporter 27 175 2.7E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c17980 6a356bfbb19d0b34f3af1bf3f786a4ee 502 Gene3D G3DSA:3.40.50.300 2 248 2.1E-57 T 12-10-2018 TSC_c18040 8393a13e594724d2253a10ace91699cb 249 SMART SM00448 5 117 7.4E-32 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c18040 8393a13e594724d2253a10ace91699cb 249 SUPERFAMILY SSF52172 6 127 6.55E-36 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c18040 8393a13e594724d2253a10ace91699cb 249 Gene3D G3DSA:3.40.50.12740 4 190 1.6E-37 T 12-10-2018 TSC_c18040 8393a13e594724d2253a10ace91699cb 249 Pfam PF00072 Response regulator receiver domain 8 117 1.5E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c09370 e63096b4c866847d5c49bd408605ecb1 264 Gene3D G3DSA:3.40.50.10860 5 245 2.6E-94 T 12-10-2018 TSC_c09370 e63096b4c866847d5c49bd408605ecb1 264 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 87 8.0E-26 T 12-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TSC_c09370 e63096b4c866847d5c49bd408605ecb1 264 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 4 261 2.5E-66 T 12-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TSC_c09370 e63096b4c866847d5c49bd408605ecb1 264 SUPERFAMILY SSF53223 3 99 9.21E-27 T 12-10-2018 TSC_c09370 e63096b4c866847d5c49bd408605ecb1 264 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 259 31.196 T 12-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 TSC_c09370 e63096b4c866847d5c49bd408605ecb1 264 Gene3D G3DSA:3.40.50.720 100 235 2.6E-94 T 12-10-2018 TSC_c09370 e63096b4c866847d5c49bd408605ecb1 264 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 119 171 5.4E-7 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase TSC_c09370 e63096b4c866847d5c49bd408605ecb1 264 SUPERFAMILY SSF51735 100 261 1.2E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c11330 1822a969864234c2eb8ca87b5a189ffc 557 Gene3D G3DSA:1.10.3720.10 352 551 2.6E-18 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c11330 1822a969864234c2eb8ca87b5a189ffc 557 Gene3D G3DSA:1.10.3720.10 51 253 5.0E-22 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c11330 1822a969864234c2eb8ca87b5a189ffc 557 SUPERFAMILY SSF161098 53 246 7.33E-18 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c11330 1822a969864234c2eb8ca87b5a189ffc 557 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 246 1.2E-11 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c11330 1822a969864234c2eb8ca87b5a189ffc 557 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 371 554 2.6E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c11330 1822a969864234c2eb8ca87b5a189ffc 557 SUPERFAMILY SSF161098 353 542 1.7E-16 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c07360 77a9ea5cda1c095c8d6ead75073ec7a5 833 SUPERFAMILY SSF55874 681 824 1.83E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c07360 77a9ea5cda1c095c8d6ead75073ec7a5 833 Gene3D G3DSA:1.20.1730.10 33 452 3.0E-11 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily TSC_c07360 77a9ea5cda1c095c8d6ead75073ec7a5 833 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 723 823 8.8E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c07360 77a9ea5cda1c095c8d6ead75073ec7a5 833 Gene3D G3DSA:1.10.287.130 599 678 1.6E-18 T 12-10-2018 TSC_c07360 77a9ea5cda1c095c8d6ead75073ec7a5 833 SUPERFAMILY SSF47384 599 680 9.81E-18 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSC_c07360 77a9ea5cda1c095c8d6ead75073ec7a5 833 SMART SM00388 613 680 4.2E-20 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c07360 77a9ea5cda1c095c8d6ead75073ec7a5 833 PRINTS PR00344 Bacterial sensor protein C-terminal signature 786 804 4.6E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c07360 77a9ea5cda1c095c8d6ead75073ec7a5 833 PRINTS PR00344 Bacterial sensor protein C-terminal signature 776 786 4.6E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c07360 77a9ea5cda1c095c8d6ead75073ec7a5 833 PRINTS PR00344 Bacterial sensor protein C-terminal signature 758 772 4.6E-10 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c07360 77a9ea5cda1c095c8d6ead75073ec7a5 833 Pfam PF00512 His Kinase A (phospho-acceptor) domain 613 680 2.4E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c07360 77a9ea5cda1c095c8d6ead75073ec7a5 833 SMART SM00387 723 824 1.8E-33 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c07360 77a9ea5cda1c095c8d6ead75073ec7a5 833 Gene3D G3DSA:3.30.565.10 679 822 1.6E-34 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c04430 b74c05f7dd565bb754c0a195d70b9c74 206 Gene3D G3DSA:3.40.50.620 1 204 3.6E-36 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c04430 b74c05f7dd565bb754c0a195d70b9c74 206 Pfam PF06508 Queuosine biosynthesis protein QueC 97 197 5.4E-20 T 12-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 TSC_c04430 b74c05f7dd565bb754c0a195d70b9c74 206 Pfam PF00733 Asparagine synthase 5 58 1.0E-4 T 12-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 TSC_c04430 b74c05f7dd565bb754c0a195d70b9c74 206 SUPERFAMILY SSF52402 1 201 7.72E-32 T 12-10-2018 TSC_c23440 31c7e8c6b916cb808b60cf89309e0cdd 133 SUPERFAMILY SSF54637 2 129 8.8E-40 T 12-10-2018 IPR029069 HotDog domain superfamily TSC_c23440 31c7e8c6b916cb808b60cf89309e0cdd 133 Pfam PF13279 Thioesterase-like superfamily 12 122 1.1E-19 T 12-10-2018 TSC_c23440 31c7e8c6b916cb808b60cf89309e0cdd 133 Gene3D G3DSA:3.10.129.10 1 133 6.4E-44 T 12-10-2018 TSC_c05880 1f6309d9451c68b61263e362663bcafa 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 6 59 1.2E-25 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c05880 1f6309d9451c68b61263e362663bcafa 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 58 20.393 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c05880 1f6309d9451c68b61263e362663bcafa 60 Pfam PF01783 Ribosomal L32p protein family 5 59 4.6E-27 T 12-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c05880 1f6309d9451c68b61263e362663bcafa 60 SUPERFAMILY SSF57829 5 60 6.71E-22 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TSC_c23200 2a333b2eda542325ed7ea20ce663ed32 254 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 246 30.835 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c23200 2a333b2eda542325ed7ea20ce663ed32 254 Gene3D G3DSA:3.30.70.660 106 249 3.6E-46 T 12-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 TSC_c23200 2a333b2eda542325ed7ea20ce663ed32 254 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 240 1.9E-48 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c23200 2a333b2eda542325ed7ea20ce663ed32 254 SUPERFAMILY SSF55120 2 249 4.17E-70 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c23200 2a333b2eda542325ed7ea20ce663ed32 254 PIRSF PIRSF001430 1 253 2.5E-70 T 12-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c23200 2a333b2eda542325ed7ea20ce663ed32 254 Gene3D G3DSA:3.30.70.580 1 105 1.4E-35 T 12-10-2018 TSC_c23200 2a333b2eda542325ed7ea20ce663ed32 254 Pfam PF01416 tRNA pseudouridine synthase 147 247 1.2E-20 T 12-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c18620 b3dcf0cf5ba1206fa4207c8b53318e2c 210 Gene3D G3DSA:3.40.50.1820 15 196 9.1E-18 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c18620 b3dcf0cf5ba1206fa4207c8b53318e2c 210 SUPERFAMILY SSF53474 20 196 3.29E-17 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c04570 e1e9601accc976025616acf579d72647 344 Gene3D G3DSA:1.20.120.1460 243 317 5.3E-32 T 12-10-2018 TSC_c04570 e1e9601accc976025616acf579d72647 344 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 87 105 - T 12-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 TSC_c04570 e1e9601accc976025616acf579d72647 344 Gene3D G3DSA:3.20.20.70 2 242 4.5E-77 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c04570 e1e9601accc976025616acf579d72647 344 Pfam PF01207 Dihydrouridine synthase (Dus) 8 304 2.1E-69 T 12-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 TSC_c04570 e1e9601accc976025616acf579d72647 344 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 1 313 43.63 T 12-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 TSC_c04570 e1e9601accc976025616acf579d72647 344 SUPERFAMILY SSF51395 4 305 6.8E-69 T 12-10-2018 TSC_c00670 1f8af57dee781d69d220419100e3df89 248 Hamap MF_00082 Acetylglutamate kinase [argB]. 2 243 40.013 T 12-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSC_c00670 1f8af57dee781d69d220419100e3df89 248 Gene3D G3DSA:3.40.1160.10 2 248 3.9E-56 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSC_c00670 1f8af57dee781d69d220419100e3df89 248 SUPERFAMILY SSF53633 5 247 9.69E-47 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSC_c00670 1f8af57dee781d69d220419100e3df89 248 TIGRFAM TIGR00761 argB: acetylglutamate kinase 6 225 2.8E-50 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSC_c00670 1f8af57dee781d69d220419100e3df89 248 PIRSF PIRSF000728 2 246 7.5E-67 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSC_c00670 1f8af57dee781d69d220419100e3df89 248 Pfam PF00696 Amino acid kinase family 6 220 1.7E-30 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSC_c08000 ba2b8ddffe728f4aa7f43a840f406578 404 SUPERFAMILY SSF63411 4 203 4.37E-39 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TSC_c08000 ba2b8ddffe728f4aa7f43a840f406578 404 Pfam PF00675 Insulinase (Peptidase family M16) 21 142 4.9E-8 T 12-10-2018 IPR011765 Peptidase M16, N-terminal TSC_c08000 ba2b8ddffe728f4aa7f43a840f406578 404 Gene3D G3DSA:3.30.830.10 218 404 4.3E-43 T 12-10-2018 TSC_c08000 ba2b8ddffe728f4aa7f43a840f406578 404 Gene3D G3DSA:3.30.830.10 2 209 6.4E-37 T 12-10-2018 TSC_c08000 ba2b8ddffe728f4aa7f43a840f406578 404 Pfam PF05193 Peptidase M16 inactive domain 165 331 6.1E-26 T 12-10-2018 IPR007863 Peptidase M16, C-terminal TSC_c08000 ba2b8ddffe728f4aa7f43a840f406578 404 SUPERFAMILY SSF63411 213 393 3.17E-36 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TSC_c07580 a16d5039a2db48ef9ef5a164bcdce5a8 556 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 552 1.3E-203 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSC_c07580 a16d5039a2db48ef9ef5a164bcdce5a8 556 SUPERFAMILY SSF52016 374 551 3.53E-59 T 12-10-2018 TSC_c07580 a16d5039a2db48ef9ef5a164bcdce5a8 556 Pfam PF00920 Dehydratase family 31 549 1.6E-197 T 12-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSC_c07580 a16d5039a2db48ef9ef5a164bcdce5a8 556 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSC_c07580 a16d5039a2db48ef9ef5a164bcdce5a8 556 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 552 44.031 T 12-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSC_c07580 a16d5039a2db48ef9ef5a164bcdce5a8 556 Gene3D G3DSA:3.50.30.80 374 523 1.2E-52 T 12-10-2018 TSC_c07580 a16d5039a2db48ef9ef5a164bcdce5a8 556 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 460 471 - T 12-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSC_c07580 a16d5039a2db48ef9ef5a164bcdce5a8 556 SUPERFAMILY SSF143975 1 373 1.57E-122 T 12-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 TSC_c06150 ea81ba0dc6b17e19341aae81839d9d5f 311 SUPERFAMILY SSF56042 144 301 3.14E-19 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSC_c06150 ea81ba0dc6b17e19341aae81839d9d5f 311 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 6 311 20.134 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TSC_c06150 ea81ba0dc6b17e19341aae81839d9d5f 311 Pfam PF00586 AIR synthase related protein, N-terminal domain 31 137 6.1E-12 T 12-10-2018 IPR016188 PurM-like, N-terminal domain TSC_c06150 ea81ba0dc6b17e19341aae81839d9d5f 311 SUPERFAMILY SSF55326 5 137 1.01E-22 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSC_c06150 ea81ba0dc6b17e19341aae81839d9d5f 311 PIRSF PIRSF005303 1 311 8.0E-61 T 12-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 TSC_c06150 ea81ba0dc6b17e19341aae81839d9d5f 311 Pfam PF02769 AIR synthase related protein, C-terminal domain 150 296 1.2E-6 T 12-10-2018 IPR010918 PurM-like, C-terminal domain TSC_c06150 ea81ba0dc6b17e19341aae81839d9d5f 311 Gene3D G3DSA:3.90.650.10 145 311 3.5E-39 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSC_c06150 ea81ba0dc6b17e19341aae81839d9d5f 311 Gene3D G3DSA:3.30.1330.10 1 142 1.2E-29 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSC_c19200 9e942f9f9b54f16d145ad5ab265c3a2d 356 Gene3D G3DSA:3.30.428.10 79 203 7.8E-79 T 12-10-2018 IPR036265 HIT-like superfamily TSC_c19200 9e942f9f9b54f16d145ad5ab265c3a2d 356 SUPERFAMILY SSF54197 47 205 1.61E-48 T 12-10-2018 IPR036265 HIT-like superfamily TSC_c19200 9e942f9f9b54f16d145ad5ab265c3a2d 356 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 233 356 6.6E-12 T 12-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TSC_c19200 9e942f9f9b54f16d145ad5ab265c3a2d 356 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 179 196 - T 12-10-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TSC_c19200 9e942f9f9b54f16d145ad5ab265c3a2d 356 PIRSF PIRSF000808 40 356 3.0E-96 T 12-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TSC_c19200 9e942f9f9b54f16d145ad5ab265c3a2d 356 Gene3D G3DSA:3.30.428.10 51 353 7.8E-79 T 12-10-2018 IPR036265 HIT-like superfamily TSC_c19200 9e942f9f9b54f16d145ad5ab265c3a2d 356 SUPERFAMILY SSF54197 229 355 3.74E-29 T 12-10-2018 IPR036265 HIT-like superfamily TSC_c19200 9e942f9f9b54f16d145ad5ab265c3a2d 356 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 48 204 1.1E-26 T 12-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TSC_c19200 9e942f9f9b54f16d145ad5ab265c3a2d 356 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 47 354 1.1E-34 T 12-10-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 TSC_c23210 cf809879e393603233b9a9e812c7c78d 397 Gene3D G3DSA:1.10.3720.10 176 392 1.2E-15 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c23210 cf809879e393603233b9a9e812c7c78d 397 SUPERFAMILY SSF161098 187 380 2.09E-17 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c23210 cf809879e393603233b9a9e812c7c78d 397 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 210 396 3.2E-30 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c23210 cf809879e393603233b9a9e812c7c78d 397 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 14 71 3.5E-20 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TSC_c22480 1a3e2d86a7ae1c25c994d530f2939e02 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 2.9E-63 T 12-10-2018 IPR023798 Ribosomal protein S7 domain TSC_c22480 1a3e2d86a7ae1c25c994d530f2939e02 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 9.5E-64 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 TSC_c22480 1a3e2d86a7ae1c25c994d530f2939e02 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 12-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22480 1a3e2d86a7ae1c25c994d530f2939e02 156 Gene3D G3DSA:1.10.455.10 6 156 4.7E-65 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TSC_c22480 1a3e2d86a7ae1c25c994d530f2939e02 156 PIRSF PIRSF002122 2 156 2.0E-62 T 12-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 TSC_c22480 1a3e2d86a7ae1c25c994d530f2939e02 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.227 T 12-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 TSC_c22480 1a3e2d86a7ae1c25c994d530f2939e02 156 SUPERFAMILY SSF47973 4 149 2.35E-59 T 12-10-2018 IPR036823 Ribosomal protein S7 domain superfamily TSC_c22060 b398a2e9be42be71559ba89d881fd97f 419 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 188 416 7.8E-52 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSC_c22060 b398a2e9be42be71559ba89d881fd97f 419 PIRSF PIRSF000185 10 419 1.7E-145 T 12-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 TSC_c22060 b398a2e9be42be71559ba89d881fd97f 419 Gene3D G3DSA:1.10.8.1210 374 419 4.8E-7 T 12-10-2018 TSC_c22060 b398a2e9be42be71559ba89d881fd97f 419 SUPERFAMILY SSF53223 13 190 6.4E-64 T 12-10-2018 TSC_c22060 b398a2e9be42be71559ba89d881fd97f 419 SMART SM00839 190 416 6.0E-62 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSC_c22060 b398a2e9be42be71559ba89d881fd97f 419 Gene3D G3DSA:1.10.8.1210 6 39 1.9E-91 T 12-10-2018 TSC_c22060 b398a2e9be42be71559ba89d881fd97f 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 221 241 9.4E-20 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSC_c22060 b398a2e9be42be71559ba89d881fd97f 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 344 355 9.4E-20 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSC_c22060 b398a2e9be42be71559ba89d881fd97f 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 179 201 9.4E-20 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSC_c22060 b398a2e9be42be71559ba89d881fd97f 419 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 99 113 9.4E-20 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSC_c22060 b398a2e9be42be71559ba89d881fd97f 419 Gene3D G3DSA:3.40.50.720 195 345 3.1E-56 T 12-10-2018 TSC_c22060 b398a2e9be42be71559ba89d881fd97f 419 Gene3D G3DSA:3.40.50.10860 40 175 1.9E-91 T 12-10-2018 TSC_c22060 b398a2e9be42be71559ba89d881fd97f 419 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 42 170 1.2E-48 T 12-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSC_c22060 b398a2e9be42be71559ba89d881fd97f 419 SUPERFAMILY SSF51735 188 418 2.44E-54 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c13980 9ee807c8bbc2688aee37eed09331e1d6 231 Gene3D G3DSA:2.40.50.140 1 84 7.0E-24 T 12-10-2018 TSC_c13980 9ee807c8bbc2688aee37eed09331e1d6 231 SUPERFAMILY SSF50249 5 78 1.11E-9 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c13980 9ee807c8bbc2688aee37eed09331e1d6 231 Pfam PF11967 Recombination protein O N terminal 8 77 3.5E-9 T 12-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal TSC_c03250 270f85bc9a670a17fdd8b297185dff86 230 Gene3D G3DSA:3.90.550.10 1 230 1.1E-71 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c03250 270f85bc9a670a17fdd8b297185dff86 230 SUPERFAMILY SSF53448 3 228 5.39E-36 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c03250 270f85bc9a670a17fdd8b297185dff86 230 Pfam PF12804 MobA-like NTP transferase domain 3 161 1.4E-15 T 12-10-2018 IPR025877 MobA-like NTP transferase TSC_c22100 91ebbee0685fccc9d5497523283b2c3d 211 SUPERFAMILY SSF51735 78 198 8.75E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c22100 91ebbee0685fccc9d5497523283b2c3d 211 Pfam PF06971 Putative DNA-binding protein N-terminus 2 50 1.8E-19 T 12-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 TSC_c22100 91ebbee0685fccc9d5497523283b2c3d 211 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 1 204 33.931 T 12-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 TSC_c22100 91ebbee0685fccc9d5497523283b2c3d 211 Gene3D G3DSA:1.10.10.10 1 73 4.1E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c22100 91ebbee0685fccc9d5497523283b2c3d 211 SMART SM00881 76 175 3.7E-15 T 12-10-2018 IPR003781 CoA-binding GO:0048037 TSC_c22100 91ebbee0685fccc9d5497523283b2c3d 211 Gene3D G3DSA:3.40.50.720 74 211 4.1E-46 T 12-10-2018 TSC_c22100 91ebbee0685fccc9d5497523283b2c3d 211 SUPERFAMILY SSF46785 4 76 2.61E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c22100 91ebbee0685fccc9d5497523283b2c3d 211 Pfam PF02629 CoA binding domain 79 173 4.6E-20 T 12-10-2018 IPR003781 CoA-binding GO:0048037 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 PRINTS PR01180 Arginine decarboxylase signature 92 106 9.9E-63 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 PRINTS PR01180 Arginine decarboxylase signature 325 342 9.9E-63 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 PRINTS PR01180 Arginine decarboxylase signature 148 163 9.9E-63 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 PRINTS PR01180 Arginine decarboxylase signature 174 195 9.9E-63 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 PRINTS PR01180 Arginine decarboxylase signature 540 561 9.9E-63 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 PRINTS PR01180 Arginine decarboxylase signature 198 220 9.9E-63 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 PRINTS PR01180 Arginine decarboxylase signature 68 83 9.9E-63 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 PRINTS PR01180 Arginine decarboxylase signature 487 512 9.9E-63 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 PRINTS PR01180 Arginine decarboxylase signature 462 483 9.9E-63 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 Gene3D G3DSA:2.40.37.10 16 567 1.5E-215 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 100 118 9.8E-19 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 124 136 9.8E-19 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 540 553 9.8E-19 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 335 354 9.8E-19 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 241 254 9.8E-19 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 Gene3D G3DSA:1.20.58.930 368 458 1.5E-215 T 12-10-2018 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 Hamap MF_01417 Biosynthetic arginine decarboxylase [speA]. 5 630 39.63 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 SUPERFAMILY SSF51419 68 347 1.44E-65 T 12-10-2018 IPR029066 PLP-binding barrel TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 PIRSF PIRSF001336 1 630 6.9E-244 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 77 345 1.1E-46 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 SUPERFAMILY SSF50621 458 569 1.49E-10 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 100 118 - T 12-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 TIGRFAM TIGR01273 speA: arginine decarboxylase 9 629 7.8E-213 T 12-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 TSC_c23290 43390c43534568dc4839bbb71c760b2f 630 Gene3D G3DSA:3.20.20.10 69 350 1.5E-215 T 12-10-2018 IPR029066 PLP-binding barrel TSC_p800030 7327840eb8a126b97257abd0449e0f32 379 SUPERFAMILY SSF53613 4 184 1.41E-27 T 12-10-2018 IPR029056 Ribokinase-like TSC_p800030 7327840eb8a126b97257abd0449e0f32 379 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 27 51 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TSC_p800030 7327840eb8a126b97257abd0449e0f32 379 Gene3D G3DSA:3.40.1190.20 2 195 1.1E-33 T 12-10-2018 IPR029056 Ribokinase-like TSC_p800030 7327840eb8a126b97257abd0449e0f32 379 Pfam PF00294 pfkB family carbohydrate kinase 2 183 1.3E-13 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB TSC_c00010 c0508c346127f75f1413553032e877f5 447 Gene3D G3DSA:3.40.50.300 99 277 2.1E-54 T 12-10-2018 TSC_c00010 c0508c346127f75f1413553032e877f5 447 Gene3D G3DSA:1.10.8.60 279 349 2.7E-24 T 12-10-2018 TSC_c00010 c0508c346127f75f1413553032e877f5 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 146 166 1.5E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TSC_c00010 c0508c346127f75f1413553032e877f5 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 210 224 1.5E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TSC_c00010 c0508c346127f75f1413553032e877f5 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 406 425 1.5E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TSC_c00010 c0508c346127f75f1413553032e877f5 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 178 192 1.5E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TSC_c00010 c0508c346127f75f1413553032e877f5 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 244 271 1.5E-51 T 12-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like TSC_c00010 c0508c346127f75f1413553032e877f5 447 SUPERFAMILY SSF52540 112 323 1.32E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c00010 c0508c346127f75f1413553032e877f5 447 SMART SM00760 356 425 2.9E-37 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 TSC_c00010 c0508c346127f75f1413553032e877f5 447 Pfam PF11638 DnaA N-terminal domain 15 75 5.3E-19 T 12-10-2018 IPR024633 DnaA N-terminal domain TSC_c00010 c0508c346127f75f1413553032e877f5 447 SMART SM00382 145 273 6.9E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c00010 c0508c346127f75f1413553032e877f5 447 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 17 445 1.0E-170 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TSC_c00010 c0508c346127f75f1413553032e877f5 447 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 14 447 33.487 T 12-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TSC_c00010 c0508c346127f75f1413553032e877f5 447 ProSitePatterns PS01008 DnaA protein signature. 406 425 - T 12-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 TSC_c00010 c0508c346127f75f1413553032e877f5 447 SUPERFAMILY SSF48295 345 446 2.38E-32 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 TSC_c00010 c0508c346127f75f1413553032e877f5 447 Gene3D G3DSA:1.10.1750.10 350 447 2.9E-32 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 TSC_c00010 c0508c346127f75f1413553032e877f5 447 Pfam PF00308 Bacterial dnaA protein 113 330 3.4E-98 T 12-10-2018 IPR013317 Chromosomal replication initiator protein DnaA TSC_c00010 c0508c346127f75f1413553032e877f5 447 Gene3D G3DSA:3.30.300.180 10 90 5.5E-17 T 12-10-2018 IPR038454 DnaA, N-terminal domain superfamily TSC_c00010 c0508c346127f75f1413553032e877f5 447 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 358 425 9.3E-28 T 12-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 TSC_c22710 3e134a9630765abfc58a6627dfbe0ad8 395 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 27 383 4.9E-130 T 12-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 TSC_c22710 3e134a9630765abfc58a6627dfbe0ad8 395 Pfam PF00155 Aminotransferase class I and II 42 383 1.2E-66 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSC_c22710 3e134a9630765abfc58a6627dfbe0ad8 395 Gene3D G3DSA:3.40.640.10 57 292 4.5E-138 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c22710 3e134a9630765abfc58a6627dfbe0ad8 395 Gene3D G3DSA:3.90.1150.10 37 385 4.5E-138 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c22710 3e134a9630765abfc58a6627dfbe0ad8 395 SUPERFAMILY SSF53383 8 393 1.88E-112 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c22710 3e134a9630765abfc58a6627dfbe0ad8 395 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 239 248 - T 12-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 TSC_c22710 3e134a9630765abfc58a6627dfbe0ad8 395 TIGRFAM TIGR01825 gly_Cac_T_rel: putative pyridoxal phosphate-dependent acyltransferase 10 394 1.5E-182 T 12-10-2018 IPR010962 Putative 8-amino-7-oxononanoate synthase, Archaea/Firmicutes type TSC_c13350 ef14e812adefb745cff0db3b4af33437 260 SUPERFAMILY SSF55729 4 138 4.8E-14 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSC_c13350 ef14e812adefb745cff0db3b4af33437 260 Pfam PF00583 Acetyltransferase (GNAT) family 19 115 4.9E-6 T 12-10-2018 IPR000182 GNAT domain TSC_c13350 ef14e812adefb745cff0db3b4af33437 260 Gene3D G3DSA:3.40.630.30 4 144 1.1E-12 T 12-10-2018 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 SUPERFAMILY SSF55608 682 800 8.5E-17 T 12-10-2018 IPR027434 Homing endonuclease TSC_c21530 fabb04436a05d6299e60780890754ece 1388 SUPERFAMILY SSF51998 205 1162 1.85E-112 T 12-10-2018 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 Gene3D G3DSA:3.20.70.20 2 178 1.0E-23 T 12-10-2018 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 6 77 2.5E-10 T 12-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 Gene3D G3DSA:2.170.16.10 448 561 3.7E-17 T 12-10-2018 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 SMART SM00305 811 856 2.1E-10 T 12-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 Pfam PF14528 LAGLIDADG-like domain 699 791 3.7E-21 T 12-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 PRINTS PR00379 Intein signature 699 711 1.4E-21 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 PRINTS PR00379 Intein signature 519 532 1.4E-21 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 PRINTS PR00379 Intein signature 845 854 1.4E-21 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 PRINTS PR00379 Intein signature 827 844 1.4E-21 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 PRINTS PR00379 Intein signature 604 616 1.4E-21 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 PRINTS PR00379 Intein signature 730 745 1.4E-21 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 829 851 3.0E-5 T 12-10-2018 IPR030934 Intein C-terminal splicing region TSC_c21530 fabb04436a05d6299e60780890754ece 1388 Pfam PF02867 Ribonucleotide reductase, barrel domain 272 1151 3.7E-104 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 Gene3D G3DSA:3.20.70.20 203 447 2.5E-49 T 12-10-2018 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 SUPERFAMILY SSF51294 446 850 1.47E-37 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 447 532 6.6E-8 T 12-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 SUPERFAMILY SSF51998 5 151 1.71E-15 T 12-10-2018 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 Pfam PF14890 Intein splicing domain 496 850 8.9E-19 T 12-10-2018 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 Gene3D G3DSA:3.20.70.20 840 1167 2.2E-111 T 12-10-2018 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 SMART SM00306 445 552 3.1E-19 T 12-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSC_c21530 fabb04436a05d6299e60780890754ece 1388 Gene3D G3DSA:3.10.28.10 602 758 8.8E-28 T 12-10-2018 IPR027434 Homing endonuclease TSC_c07220 b56c7adbd1bf0ab1fdb8fa63bc7a0a44 259 Gene3D G3DSA:3.10.180.10 5 127 2.8E-27 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c07220 b56c7adbd1bf0ab1fdb8fa63bc7a0a44 259 Gene3D G3DSA:3.10.180.10 158 231 5.8E-11 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c07220 b56c7adbd1bf0ab1fdb8fa63bc7a0a44 259 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 119 6.7E-12 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TSC_c07220 b56c7adbd1bf0ab1fdb8fa63bc7a0a44 259 SUPERFAMILY SSF54593 5 148 7.52E-36 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c07220 b56c7adbd1bf0ab1fdb8fa63bc7a0a44 259 SUPERFAMILY SSF54593 154 251 9.13E-17 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 SUPERFAMILY SSF50249 283 386 1.07E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 Pfam PF00575 S1 RNA binding domain 126 194 6.8E-12 T 12-10-2018 IPR003029 S1 domain GO:0003676 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 Pfam PF00575 S1 RNA binding domain 213 283 6.0E-22 T 12-10-2018 IPR003029 S1 domain GO:0003676 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 Pfam PF00575 S1 RNA binding domain 385 456 8.3E-20 T 12-10-2018 IPR003029 S1 domain GO:0003676 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 Pfam PF00575 S1 RNA binding domain 37 110 3.4E-10 T 12-10-2018 IPR003029 S1 domain GO:0003676 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 Pfam PF00575 S1 RNA binding domain 297 370 1.5E-19 T 12-10-2018 IPR003029 S1 domain GO:0003676 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 Gene3D G3DSA:2.40.50.140 290 381 2.5E-30 T 12-10-2018 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 Gene3D G3DSA:2.40.50.140 200 285 1.1E-28 T 12-10-2018 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 SUPERFAMILY SSF50249 19 135 4.56E-22 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 Gene3D G3DSA:2.40.50.140 382 466 3.2E-28 T 12-10-2018 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 SUPERFAMILY SSF50249 212 300 9.7E-28 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 SUPERFAMILY SSF50249 125 208 2.16E-17 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 SUPERFAMILY SSF50249 370 460 1.44E-26 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 Gene3D G3DSA:2.40.50.140 25 120 2.4E-21 T 12-10-2018 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 PRINTS PR00681 Ribosomal protein S1 signature 39 57 7.8E-58 T 12-10-2018 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 PRINTS PR00681 Ribosomal protein S1 signature 178 198 7.8E-58 T 12-10-2018 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 PRINTS PR00681 Ribosomal protein S1 signature 57 71 7.8E-58 T 12-10-2018 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 PRINTS PR00681 Ribosomal protein S1 signature 313 332 7.8E-58 T 12-10-2018 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 PRINTS PR00681 Ribosomal protein S1 signature 149 166 7.8E-58 T 12-10-2018 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 PRINTS PR00681 Ribosomal protein S1 signature 353 371 7.8E-58 T 12-10-2018 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 PRINTS PR00681 Ribosomal protein S1 signature 107 126 7.8E-58 T 12-10-2018 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 PRINTS PR00681 Ribosomal protein S1 signature 131 147 7.8E-58 T 12-10-2018 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 PRINTS PR00681 Ribosomal protein S1 signature 235 256 7.8E-58 T 12-10-2018 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 Gene3D G3DSA:2.40.50.140 121 199 7.0E-13 T 12-10-2018 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 SMART SM00316 126 194 5.2E-14 T 12-10-2018 IPR022967 RNA-binding domain, S1 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 SMART SM00316 298 370 5.6E-27 T 12-10-2018 IPR022967 RNA-binding domain, S1 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 SMART SM00316 213 283 1.6E-27 T 12-10-2018 IPR022967 RNA-binding domain, S1 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 SMART SM00316 37 110 2.9E-17 T 12-10-2018 IPR022967 RNA-binding domain, S1 TSC_c23680 abe55ed7c9649d544d3942b9ac4cb5de 539 SMART SM00316 385 456 4.8E-26 T 12-10-2018 IPR022967 RNA-binding domain, S1 TSC_c13500 d054c61be668490ccb17e29651595f64 372 Gene3D G3DSA:3.90.1150.10 24 364 1.2E-136 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c13500 d054c61be668490ccb17e29651595f64 372 Pfam PF00155 Aminotransferase class I and II 28 364 4.2E-55 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSC_c13500 d054c61be668490ccb17e29651595f64 372 SUPERFAMILY SSF53383 5 366 3.72E-99 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c13500 d054c61be668490ccb17e29651595f64 372 Gene3D G3DSA:3.40.640.10 40 270 1.2E-136 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c17050 dc3931af959fba45b0d8abd6aa115ac4 399 SUPERFAMILY SSF53335 128 395 1.66E-44 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c17050 dc3931af959fba45b0d8abd6aa115ac4 399 SUPERFAMILY SSF48013 6 139 8.67E-25 T 12-10-2018 IPR035926 NusB-like superfamily TSC_c17050 dc3931af959fba45b0d8abd6aa115ac4 399 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 329 345 9.0E-15 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSC_c17050 dc3931af959fba45b0d8abd6aa115ac4 399 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 279 291 9.0E-15 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSC_c17050 dc3931af959fba45b0d8abd6aa115ac4 399 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 377 394 9.0E-15 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSC_c17050 dc3931af959fba45b0d8abd6aa115ac4 399 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 219 229 9.0E-15 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSC_c17050 dc3931af959fba45b0d8abd6aa115ac4 399 Pfam PF01189 16S rRNA methyltransferase RsmB/F 208 391 1.8E-30 T 12-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TSC_c17050 dc3931af959fba45b0d8abd6aa115ac4 399 Pfam PF01029 NusB family 6 122 8.9E-18 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TSC_c17050 dc3931af959fba45b0d8abd6aa115ac4 399 Gene3D G3DSA:1.10.940.10 2 133 3.7E-26 T 12-10-2018 IPR035926 NusB-like superfamily TSC_c17050 dc3931af959fba45b0d8abd6aa115ac4 399 Gene3D G3DSA:3.40.50.150 152 394 8.7E-44 T 12-10-2018 TSC_c03580 7de9c3e52776fc24f2f01836d8528ce6 110 PRINTS PR00421 Thioredoxin family signature 22 30 7.1E-8 T 12-10-2018 TSC_c03580 7de9c3e52776fc24f2f01836d8528ce6 110 PRINTS PR00421 Thioredoxin family signature 30 39 7.1E-8 T 12-10-2018 TSC_c03580 7de9c3e52776fc24f2f01836d8528ce6 110 PRINTS PR00421 Thioredoxin family signature 70 81 7.1E-8 T 12-10-2018 TSC_c03580 7de9c3e52776fc24f2f01836d8528ce6 110 ProSitePatterns PS00194 Thioredoxin family active site. 23 41 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 TSC_c03580 7de9c3e52776fc24f2f01836d8528ce6 110 TIGRFAM TIGR01068 thioredoxin: thioredoxin 8 105 1.4E-38 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TSC_c03580 7de9c3e52776fc24f2f01836d8528ce6 110 Gene3D G3DSA:3.40.30.10 2 110 2.6E-37 T 12-10-2018 TSC_c03580 7de9c3e52776fc24f2f01836d8528ce6 110 Pfam PF00085 Thioredoxin 5 105 8.0E-32 T 12-10-2018 IPR013766 Thioredoxin domain GO:0045454 TSC_c03580 7de9c3e52776fc24f2f01836d8528ce6 110 PIRSF PIRSF000077 1 106 2.4E-41 T 12-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 TSC_c03580 7de9c3e52776fc24f2f01836d8528ce6 110 SUPERFAMILY SSF52833 3 107 8.96E-41 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TSC_c07440 55c4f07553e91e934d890532f95e8d0c 843 Gene3D G3DSA:1.10.10.10 5 73 3.7E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c07440 55c4f07553e91e934d890532f95e8d0c 843 SUPERFAMILY SSF56801 265 824 1.44E-136 T 12-10-2018 TSC_c07440 55c4f07553e91e934d890532f95e8d0c 843 Pfam PF00501 AMP-binding enzyme 324 725 7.8E-73 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSC_c07440 55c4f07553e91e934d890532f95e8d0c 843 Pfam PF01614 Bacterial transcriptional regulator 124 209 1.5E-15 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal TSC_c07440 55c4f07553e91e934d890532f95e8d0c 843 ProSitePatterns PS00455 Putative AMP-binding domain signature. 481 492 - T 12-10-2018 IPR020845 AMP-binding, conserved site TSC_c07440 55c4f07553e91e934d890532f95e8d0c 843 Gene3D G3DSA:3.30.450.40 77 241 1.3E-27 T 12-10-2018 IPR029016 GAF-like domain superfamily TSC_c07440 55c4f07553e91e934d890532f95e8d0c 843 Gene3D G3DSA:3.30.300.30 720 823 5.4E-21 T 12-10-2018 TSC_c07440 55c4f07553e91e934d890532f95e8d0c 843 Pfam PF09339 IclR helix-turn-helix domain 13 57 4.0E-11 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSC_c07440 55c4f07553e91e934d890532f95e8d0c 843 SUPERFAMILY SSF55781 80 225 4.32E-21 T 12-10-2018 TSC_c07440 55c4f07553e91e934d890532f95e8d0c 843 SUPERFAMILY SSF46785 8 67 8.24E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c07440 55c4f07553e91e934d890532f95e8d0c 843 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 269 317 5.0E-14 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 TSC_c07440 55c4f07553e91e934d890532f95e8d0c 843 Gene3D G3DSA:3.40.50.12780 295 718 5.2E-94 T 12-10-2018 TSC_c07440 55c4f07553e91e934d890532f95e8d0c 843 Pfam PF13193 AMP-binding enzyme C-terminal domain 734 812 1.2E-17 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSC_c23090 b39e711cd034c90f318ce7dfe1983473 355 Gene3D G3DSA:3.90.1150.10 11 348 1.3E-98 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c23090 b39e711cd034c90f318ce7dfe1983473 355 SUPERFAMILY SSF53383 12 354 4.21E-81 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c23090 b39e711cd034c90f318ce7dfe1983473 355 Pfam PF00155 Aminotransferase class I and II 33 349 5.3E-34 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSC_c23090 b39e711cd034c90f318ce7dfe1983473 355 Gene3D G3DSA:3.40.640.10 50 259 1.3E-98 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c14430 30683adbe09ded6f07b5d8cd2cb266d3 286 Pfam PF01795 MraW methylase family 6 283 1.3E-99 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TSC_c14430 30683adbe09ded6f07b5d8cd2cb266d3 286 PIRSF PIRSF004486 1 285 1.5E-103 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TSC_c14430 30683adbe09ded6f07b5d8cd2cb266d3 286 SUPERFAMILY SSF53335 7 283 1.37E-53 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c14430 30683adbe09ded6f07b5d8cd2cb266d3 286 Gene3D G3DSA:3.40.50.150 7 282 8.1E-117 T 12-10-2018 TSC_c14430 30683adbe09ded6f07b5d8cd2cb266d3 286 SUPERFAMILY SSF81799 110 207 1.09E-34 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 TSC_c14430 30683adbe09ded6f07b5d8cd2cb266d3 286 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 4 283 4.2E-98 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TSC_c14430 30683adbe09ded6f07b5d8cd2cb266d3 286 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 284 37.689 T 12-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 TSC_c14430 30683adbe09ded6f07b5d8cd2cb266d3 286 Gene3D G3DSA:1.10.150.170 108 208 8.1E-117 T 12-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 TSC_c18530 9b5fcfe90a04a0f819fc603a8e5fb5b5 592 SUPERFAMILY SSF50249 164 531 3.3E-88 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c18530 9b5fcfe90a04a0f819fc603a8e5fb5b5 592 Pfam PF00773 RNB domain 442 489 2.2E-12 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 TSC_c18530 9b5fcfe90a04a0f819fc603a8e5fb5b5 592 SUPERFAMILY SSF50249 533 590 4.11E-11 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c18530 9b5fcfe90a04a0f819fc603a8e5fb5b5 592 SMART SM00955 217 490 2.1E-77 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 TSC_c18530 9b5fcfe90a04a0f819fc603a8e5fb5b5 592 Gene3D G3DSA:1.10.10.10 141 208 1.5E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c18530 9b5fcfe90a04a0f819fc603a8e5fb5b5 592 Pfam PF00773 RNB domain 217 428 2.2E-40 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 TSC_c12290 2e6464dc1e26b1adbff9a9dafe68c4b1 107 Pfam PF13384 Homeodomain-like domain 43 94 8.1E-12 T 12-10-2018 TSC_c12290 2e6464dc1e26b1adbff9a9dafe68c4b1 107 SUPERFAMILY SSF48295 49 100 3.3E-8 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 TSC_c12690 2e6464dc1e26b1adbff9a9dafe68c4b1 107 Pfam PF13384 Homeodomain-like domain 43 94 8.1E-12 T 12-10-2018 TSC_c12690 2e6464dc1e26b1adbff9a9dafe68c4b1 107 SUPERFAMILY SSF48295 49 100 3.3E-8 T 12-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 TSC_c19860 5d4ead61df4f13bbe0328c0c7ba28fc0 164 SUPERFAMILY SSF52317 3 138 4.78E-14 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c19860 5d4ead61df4f13bbe0328c0c7ba28fc0 164 Pfam PF01965 DJ-1/PfpI family 3 146 1.1E-7 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TSC_c19860 5d4ead61df4f13bbe0328c0c7ba28fc0 164 Gene3D G3DSA:3.40.50.880 2 162 2.1E-15 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c03670 36ad88b19819a38d8ee7dbd9cf3f2a1d 322 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 1 313 33.222 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSC_c03670 36ad88b19819a38d8ee7dbd9cf3f2a1d 322 SUPERFAMILY SSF51735 1 171 8.93E-45 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c03670 36ad88b19819a38d8ee7dbd9cf3f2a1d 322 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 191 215 5.3E-43 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSC_c03670 36ad88b19819a38d8ee7dbd9cf3f2a1d 322 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 5 22 5.3E-43 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSC_c03670 36ad88b19819a38d8ee7dbd9cf3f2a1d 322 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 231 248 5.3E-43 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSC_c03670 36ad88b19819a38d8ee7dbd9cf3f2a1d 322 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 127 147 5.3E-43 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSC_c03670 36ad88b19819a38d8ee7dbd9cf3f2a1d 322 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 166 190 5.3E-43 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSC_c03670 36ad88b19819a38d8ee7dbd9cf3f2a1d 322 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 55 82 5.3E-43 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSC_c03670 36ad88b19819a38d8ee7dbd9cf3f2a1d 322 PIRSF PIRSF000114 1 322 2.0E-88 T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSC_c03670 36ad88b19819a38d8ee7dbd9cf3f2a1d 322 Gene3D G3DSA:3.40.50.720 1 181 1.2E-51 T 12-10-2018 TSC_c03670 36ad88b19819a38d8ee7dbd9cf3f2a1d 322 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 173 310 1.7E-47 T 12-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSC_c03670 36ad88b19819a38d8ee7dbd9cf3f2a1d 322 Gene3D G3DSA:1.10.1040.10 182 322 1.0E-46 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSC_c03670 36ad88b19819a38d8ee7dbd9cf3f2a1d 322 SUPERFAMILY SSF48179 172 322 7.65E-48 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSC_c03670 36ad88b19819a38d8ee7dbd9cf3f2a1d 322 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2 148 4.4E-39 T 12-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSC_c03670 36ad88b19819a38d8ee7dbd9cf3f2a1d 322 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 181 202 - T 12-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 TSC_c16760 67341619040e54161fb0a24216c528f8 184 Pfam PF13808 DDE_Tnp_1-associated 5 86 2.3E-15 T 12-10-2018 IPR032806 H repeat-associated protein, N-terminal TSC_c05200 67341619040e54161fb0a24216c528f8 184 Pfam PF13808 DDE_Tnp_1-associated 5 86 2.3E-15 T 12-10-2018 IPR032806 H repeat-associated protein, N-terminal TSC_c14160 67341619040e54161fb0a24216c528f8 184 Pfam PF13808 DDE_Tnp_1-associated 5 86 2.3E-15 T 12-10-2018 IPR032806 H repeat-associated protein, N-terminal TSC_c14730 e4331e386b0d6f9f67711b07cb915387 388 Gene3D G3DSA:3.40.710.10 1 370 4.4E-101 T 12-10-2018 TSC_c14730 e4331e386b0d6f9f67711b07cb915387 388 SUPERFAMILY SSF56601 3 357 4.75E-78 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSC_c14730 e4331e386b0d6f9f67711b07cb915387 388 Pfam PF00144 Beta-lactamase 7 355 4.0E-55 T 12-10-2018 IPR001466 Beta-lactamase-related TSC_c15540 adcccc566cc3af9cf2c458efab7d75d3 119 Pfam PF01022 Bacterial regulatory protein, arsR family 41 86 1.3E-14 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c15540 adcccc566cc3af9cf2c458efab7d75d3 119 SMART SM00418 34 113 3.0E-31 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c15540 adcccc566cc3af9cf2c458efab7d75d3 119 Gene3D G3DSA:1.10.10.10 2 118 3.2E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c15540 adcccc566cc3af9cf2c458efab7d75d3 119 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 58 76 - T 12-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 TSC_c15540 adcccc566cc3af9cf2c458efab7d75d3 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 7.5E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c15540 adcccc566cc3af9cf2c458efab7d75d3 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 7.5E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c15540 adcccc566cc3af9cf2c458efab7d75d3 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 67 7.5E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c15540 adcccc566cc3af9cf2c458efab7d75d3 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 7.5E-20 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c15540 adcccc566cc3af9cf2c458efab7d75d3 119 SUPERFAMILY SSF46785 23 114 1.18E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c19670 ff80386e3171f25cc6f9f9d9d590d2e8 208 Gene3D G3DSA:3.10.580.10 1 142 2.4E-39 T 12-10-2018 TSC_c19670 ff80386e3171f25cc6f9f9d9d590d2e8 208 SMART SM00116 10 57 1.5E-13 T 12-10-2018 IPR000644 CBS domain TSC_c19670 ff80386e3171f25cc6f9f9d9d590d2e8 208 SMART SM00116 78 125 1.0E-11 T 12-10-2018 IPR000644 CBS domain TSC_c19670 ff80386e3171f25cc6f9f9d9d590d2e8 208 Pfam PF00571 CBS domain 3 55 7.6E-15 T 12-10-2018 IPR000644 CBS domain TSC_c19670 ff80386e3171f25cc6f9f9d9d590d2e8 208 Pfam PF00571 CBS domain 71 125 4.9E-15 T 12-10-2018 IPR000644 CBS domain TSC_c19670 ff80386e3171f25cc6f9f9d9d590d2e8 208 SUPERFAMILY SSF55021 137 201 4.93E-8 T 12-10-2018 TSC_c19670 ff80386e3171f25cc6f9f9d9d590d2e8 208 SUPERFAMILY SSF54631 1 127 4.93E-35 T 12-10-2018 TSC_c19670 ff80386e3171f25cc6f9f9d9d590d2e8 208 Pfam PF01842 ACT domain 136 181 3.6E-8 T 12-10-2018 IPR002912 ACT domain TSC_c05790 e98afc87c0fe6d7c8f6ef04ccfdd9dd8 319 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 73 78 - T 12-10-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 TSC_c05790 e98afc87c0fe6d7c8f6ef04ccfdd9dd8 319 Pfam PF01555 DNA methylase 69 302 3.1E-35 T 12-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 TSC_c05790 e98afc87c0fe6d7c8f6ef04ccfdd9dd8 319 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 68 82 4.5E-29 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TSC_c05790 e98afc87c0fe6d7c8f6ef04ccfdd9dd8 319 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 244 261 4.5E-29 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TSC_c05790 e98afc87c0fe6d7c8f6ef04ccfdd9dd8 319 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 263 281 4.5E-29 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TSC_c05790 e98afc87c0fe6d7c8f6ef04ccfdd9dd8 319 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 286 306 4.5E-29 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TSC_c05790 e98afc87c0fe6d7c8f6ef04ccfdd9dd8 319 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 107 127 4.5E-29 T 12-10-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 TSC_c05790 e98afc87c0fe6d7c8f6ef04ccfdd9dd8 319 SUPERFAMILY SSF53335 50 307 9.37E-56 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c05790 e98afc87c0fe6d7c8f6ef04ccfdd9dd8 319 Gene3D G3DSA:3.40.50.150 50 318 6.9E-85 T 12-10-2018 TSC_c07960 e6fe22d39ad6b5bcbc570eeb1d935da4 329 Pfam PF03283 Pectinacetylesterase 27 204 6.8E-27 T 12-10-2018 IPR004963 Pectinacetylesterase/NOTUM GO:0016787 Reactome: R-HSA-381426|Reactome: R-HSA-5362798|Reactome: R-HSA-8957275 TSC_c07960 e6fe22d39ad6b5bcbc570eeb1d935da4 329 SUPERFAMILY SSF53474 35 303 1.99E-12 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c07960 e6fe22d39ad6b5bcbc570eeb1d935da4 329 Gene3D G3DSA:3.40.50.1820 38 305 3.2E-8 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c20770 ed16f5428b0379a549e74b2b426c0e92 125 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 119 19.793 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 TSC_c20770 ed16f5428b0379a549e74b2b426c0e92 125 SUPERFAMILY SSF56214 1 118 7.59E-20 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TSC_c20770 ed16f5428b0379a549e74b2b426c0e92 125 Gene3D G3DSA:3.90.470.20 1 119 4.6E-28 T 12-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TSC_c20770 ed16f5428b0379a549e74b2b426c0e92 125 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 5 81 1.8E-12 T 12-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 TSC_c20770 ed16f5428b0379a549e74b2b426c0e92 125 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 2 119 1.7E-16 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 TSC_c20770 ed16f5428b0379a549e74b2b426c0e92 125 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 61 4.0E-13 T 12-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 TSC_c20770 ed16f5428b0379a549e74b2b426c0e92 125 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 119 6.6E-18 T 12-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 TSC_c17010 f35a7e6aef18d5497b5a314f532d615c 336 Pfam PF02163 Peptidase family M50 6 321 1.8E-51 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TSC_c17010 f35a7e6aef18d5497b5a314f532d615c 336 Gene3D G3DSA:2.30.42.10 100 184 1.2E-15 T 12-10-2018 TSC_c17010 f35a7e6aef18d5497b5a314f532d615c 336 SMART SM00228 85 174 1.6E-8 T 12-10-2018 IPR001478 PDZ domain GO:0005515 TSC_c17010 f35a7e6aef18d5497b5a314f532d615c 336 Pfam PF13180 PDZ domain 118 182 2.9E-7 T 12-10-2018 IPR001478 PDZ domain GO:0005515 TSC_c17010 f35a7e6aef18d5497b5a314f532d615c 336 SUPERFAMILY SSF50156 89 182 4.21E-17 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 TSC_c12960 df7bc9be802b326e678eed6f1424c6dd 490 Gene3D G3DSA:3.10.20.600 332 411 4.1E-11 T 12-10-2018 TSC_c12960 df7bc9be802b326e678eed6f1424c6dd 490 Gene3D G3DSA:3.40.50.11540 165 331 3.0E-65 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c12960 df7bc9be802b326e678eed6f1424c6dd 490 Gene3D G3DSA:1.20.1440.230 414 486 1.9E-13 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c12960 df7bc9be802b326e678eed6f1424c6dd 490 SUPERFAMILY SSF142984 337 395 2.48E-9 T 12-10-2018 TSC_c12960 df7bc9be802b326e678eed6f1424c6dd 490 SUPERFAMILY SSF140490 413 485 2.48E-15 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c12960 df7bc9be802b326e678eed6f1424c6dd 490 Pfam PF10531 SLBB domain 339 380 2.0E-7 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c12960 df7bc9be802b326e678eed6f1424c6dd 490 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 419 485 1.7E-12 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c12960 df7bc9be802b326e678eed6f1424c6dd 490 SMART SM00928 416 461 1.2E-5 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c12960 df7bc9be802b326e678eed6f1424c6dd 490 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 160 321 4.8E-44 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c12960 df7bc9be802b326e678eed6f1424c6dd 490 SUPERFAMILY SSF142019 129 331 2.09E-65 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c13920 6365e1eb2db6f8cf1d6957bb26662db3 130 SUPERFAMILY SSF50324 4 108 2.09E-14 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSC_c13920 6365e1eb2db6f8cf1d6957bb26662db3 130 Pfam PF00719 Inorganic pyrophosphatase 6 85 5.2E-6 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSC_c13920 6365e1eb2db6f8cf1d6957bb26662db3 130 Gene3D G3DSA:3.90.80.10 2 125 5.5E-9 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSC_c11950 b8336b4273b777c200eaa5e7c7514fb2 549 SMART SM00052 300 535 1.1E-38 T 12-10-2018 IPR001633 EAL domain TSC_c11950 b8336b4273b777c200eaa5e7c7514fb2 549 SMART SM00267 123 290 2.4E-44 T 12-10-2018 IPR000160 GGDEF domain TSC_c11950 b8336b4273b777c200eaa5e7c7514fb2 549 Gene3D G3DSA:3.30.70.270 132 300 7.9E-45 T 12-10-2018 TSC_c11950 b8336b4273b777c200eaa5e7c7514fb2 549 SMART SM00091 9 76 8.0E-11 T 12-10-2018 IPR000014 PAS domain TSC_c11950 b8336b4273b777c200eaa5e7c7514fb2 549 Pfam PF00989 PAS fold 11 120 4.3E-19 T 12-10-2018 IPR013767 PAS fold GO:0006355 TSC_c11950 b8336b4273b777c200eaa5e7c7514fb2 549 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 130 280 2.9E-32 T 12-10-2018 IPR000160 GGDEF domain TSC_c11950 b8336b4273b777c200eaa5e7c7514fb2 549 Pfam PF00990 Diguanylate cyclase, GGDEF domain 134 280 1.3E-34 T 12-10-2018 IPR000160 GGDEF domain TSC_c11950 b8336b4273b777c200eaa5e7c7514fb2 549 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 9 125 1.3E-22 T 12-10-2018 IPR000014 PAS domain TSC_c11950 b8336b4273b777c200eaa5e7c7514fb2 549 Pfam PF00563 EAL domain 306 534 4.3E-48 T 12-10-2018 IPR001633 EAL domain TSC_c11950 b8336b4273b777c200eaa5e7c7514fb2 549 SUPERFAMILY SSF55785 15 121 1.74E-28 T 12-10-2018 IPR035965 PAS domain superfamily TSC_c11950 b8336b4273b777c200eaa5e7c7514fb2 549 Gene3D G3DSA:3.30.450.20 8 131 7.4E-33 T 12-10-2018 TSC_c11950 b8336b4273b777c200eaa5e7c7514fb2 549 SUPERFAMILY SSF55073 139 280 4.87E-37 T 12-10-2018 IPR029787 Nucleotide cyclase TSC_c11950 b8336b4273b777c200eaa5e7c7514fb2 549 SMART SM00086 81 123 1.9E-7 T 12-10-2018 IPR001610 PAC motif TSC_c11950 b8336b4273b777c200eaa5e7c7514fb2 549 Gene3D G3DSA:3.20.20.450 301 540 9.3E-58 T 12-10-2018 IPR035919 EAL domain superfamily TSC_c11950 b8336b4273b777c200eaa5e7c7514fb2 549 SUPERFAMILY SSF141868 306 534 6.54E-52 T 12-10-2018 IPR035919 EAL domain superfamily TSC_c08750 6ab72502529876bdc1391a67ae50c5af 199 Gene3D G3DSA:1.20.5.620 13 108 8.2E-26 T 12-10-2018 TSC_c08750 6ab72502529876bdc1391a67ae50c5af 199 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 13 199 10.714 T 12-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c08750 6ab72502529876bdc1391a67ae50c5af 199 SUPERFAMILY SSF160527 89 199 4.71E-13 T 12-10-2018 TSC_c08750 6ab72502529876bdc1391a67ae50c5af 199 Gene3D G3DSA:3.30.2320.30 109 199 3.2E-21 T 12-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c22380 111a5ec8c8991182e0d37317884678eb 239 SUPERFAMILY SSF54821 108 206 2.35E-35 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22380 111a5ec8c8991182e0d37317884678eb 239 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 209 2.8E-83 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 TSC_c22380 111a5ec8c8991182e0d37317884678eb 239 SMART SM00322 60 125 7.1E-5 T 12-10-2018 IPR004087 K Homology domain GO:0003676 TSC_c22380 111a5ec8c8991182e0d37317884678eb 239 SUPERFAMILY SSF54814 2 106 5.23E-37 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TSC_c22380 111a5ec8c8991182e0d37317884678eb 239 Pfam PF00189 Ribosomal protein S3, C-terminal domain 120 200 8.1E-34 T 12-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22380 111a5ec8c8991182e0d37317884678eb 239 Pfam PF07650 KH domain 39 110 9.5E-17 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22380 111a5ec8c8991182e0d37317884678eb 239 Gene3D G3DSA:3.30.300.20 17 107 4.2E-30 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TSC_c22380 111a5ec8c8991182e0d37317884678eb 239 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 12-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22380 111a5ec8c8991182e0d37317884678eb 239 Gene3D G3DSA:3.30.1140.32 108 208 1.4E-38 T 12-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22380 111a5ec8c8991182e0d37317884678eb 239 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 36.004 T 12-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 SMART SM00316 595 674 3.3E-6 T 12-10-2018 IPR022967 RNA-binding domain, S1 TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 SUPERFAMILY SSF50249 109 203 6.28E-13 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 Gene3D G3DSA:2.40.50.140 598 701 1.0E-11 T 12-10-2018 TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 56 671 5.2E-147 T 12-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 Gene3D G3DSA:2.40.50.140 57 118 8.3E-9 T 12-10-2018 TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 SUPERFAMILY SSF50249 57 118 1.0E-9 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 Hamap MF_01895 Ribonuclease R [rnr]. 19 674 52.485 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 SMART SM00955 226 548 1.0E-156 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 SUPERFAMILY SSF46785 2 53 5.84E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 ProSitePatterns PS01175 Ribonuclease II family signature. 515 539 - T 12-10-2018 IPR022966 Ribonuclease II/R, conserved site TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 TIGRFAM TIGR02063 RNase_R: ribonuclease R 1 671 1.2E-195 T 12-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 Gene3D G3DSA:1.10.10.10 4 56 1.8E-6 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 Pfam PF00575 S1 RNA binding domain 596 660 2.3E-5 T 12-10-2018 IPR003029 S1 domain GO:0003676 TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 Pfam PF08206 Ribonuclease B OB domain 60 115 8.1E-9 T 12-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 Pfam PF09339 IclR helix-turn-helix domain 5 48 3.2E-5 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 SUPERFAMILY SSF50249 597 672 1.12E-11 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 SUPERFAMILY SSF50249 186 591 1.94E-133 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c09440 328975eef2b1716c48d823c618b88fa8 746 Pfam PF00773 RNB domain 226 547 3.8E-112 T 12-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 TSC_c00900 d424d85517682efd75a15d53fada575c 529 PIRSF PIRSF006294 1 528 1.1E-237 T 12-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 TSC_c00900 d424d85517682efd75a15d53fada575c 529 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 3 528 1.4E-215 T 12-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 TSC_c00900 d424d85517682efd75a15d53fada575c 529 Pfam PF01293 Phosphoenolpyruvate carboxykinase 14 481 4.2E-216 T 12-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 TSC_c00900 d424d85517682efd75a15d53fada575c 529 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 8 528 55.054 T 12-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 TSC_c00900 d424d85517682efd75a15d53fada575c 529 Gene3D G3DSA:2.170.8.10 34 330 1.3E-232 T 12-10-2018 TSC_c00900 d424d85517682efd75a15d53fada575c 529 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 249 264 - T 12-10-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 TSC_c00900 d424d85517682efd75a15d53fada575c 529 SUPERFAMILY SSF53795 212 527 3.27E-136 T 12-10-2018 TSC_c00900 d424d85517682efd75a15d53fada575c 529 Gene3D G3DSA:3.90.228.20 213 513 1.3E-232 T 12-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TSC_c00900 d424d85517682efd75a15d53fada575c 529 Gene3D G3DSA:3.40.449.10 24 212 1.3E-232 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TSC_c00900 d424d85517682efd75a15d53fada575c 529 SUPERFAMILY SSF68923 4 211 1.43E-80 T 12-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 Pfam PF14528 LAGLIDADG-like domain 599 680 1.6E-16 T 12-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 Gene3D G3DSA:1.10.860.10 1 149 1.3E-59 T 12-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 Gene3D G3DSA:3.40.50.300 157 388 2.0E-78 T 12-10-2018 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 Gene3D G3DSA:3.40.50.300 807 871 6.8E-19 T 12-10-2018 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 SUPERFAMILY SSF52540 803 859 8.69E-6 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 PRINTS PR00379 Intein signature 446 459 5.1E-28 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 PRINTS PR00379 Intein signature 632 647 5.1E-28 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 PRINTS PR00379 Intein signature 493 505 5.1E-28 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 PRINTS PR00379 Intein signature 599 611 5.1E-28 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 PRINTS PR00379 Intein signature 806 815 5.1E-28 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 PRINTS PR00379 Intein signature 788 805 5.1E-28 T 12-10-2018 IPR006142 Intein GO:0016539 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 790 812 1.3E-7 T 12-10-2018 IPR030934 Intein C-terminal splicing region TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 SUPERFAMILY SSF51294 383 811 4.58E-51 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 SUPERFAMILY SSF52540 180 388 9.3E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 Gene3D G3DSA:3.10.28.10 493 673 1.2E-28 T 12-10-2018 IPR027434 Homing endonuclease TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 Pfam PF00772 DnaB-like helicase N terminal domain 6 108 1.1E-33 T 12-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 Pfam PF03796 DnaB-like helicase C terminal domain 182 867 3.9E-106 T 12-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 SUPERFAMILY SSF48024 4 116 7.59E-35 T 12-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 Gene3D G3DSA:2.170.16.10 389 492 2.9E-25 T 12-10-2018 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 Gene3D G3DSA:2.170.16.10 720 806 6.6E-17 T 12-10-2018 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 SMART SM00306 382 479 9.1E-27 T 12-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 Pfam PF14890 Intein splicing domain 391 811 1.6E-49 T 12-10-2018 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 SMART SM00305 772 817 3.3E-14 T 12-10-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 6 869 7.3E-167 T 12-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 384 459 1.2E-10 T 12-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSC_c20460 8f61397862cc2983c3ea298c0088fa21 872 SUPERFAMILY SSF55608 581 688 6.23E-14 T 12-10-2018 IPR027434 Homing endonuclease TSC_c11370 ab23519786149f2bcc8b2e6b5cef0651 317 SUPERFAMILY SSF53335 121 183 2.28E-10 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c11370 ab23519786149f2bcc8b2e6b5cef0651 317 Gene3D G3DSA:3.40.50.150 121 195 4.8E-9 T 12-10-2018 TSC_c11370 ab23519786149f2bcc8b2e6b5cef0651 317 SUPERFAMILY SSF53335 146 263 1.53E-8 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c11370 ab23519786149f2bcc8b2e6b5cef0651 317 Pfam PF01555 DNA methylase 133 182 1.2E-6 T 12-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 TSC_c13360 440f102b140e29f796c6a2e85f5b9b28 369 Pfam PF01979 Amidohydrolase family 61 366 3.4E-30 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSC_c13360 440f102b140e29f796c6a2e85f5b9b28 369 SUPERFAMILY SSF51556 61 353 2.42E-64 T 12-10-2018 IPR032466 Metal-dependent hydrolase TSC_c13360 440f102b140e29f796c6a2e85f5b9b28 369 Gene3D G3DSA:2.30.40.10 7 366 9.5E-92 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSC_c13360 440f102b140e29f796c6a2e85f5b9b28 369 SUPERFAMILY SSF51338 7 77 4.46E-16 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSC_c13360 440f102b140e29f796c6a2e85f5b9b28 369 Gene3D G3DSA:3.20.20.140 16 356 9.5E-92 T 12-10-2018 TSC_c08500 e1316435ec548aebd841f02870d1818e 145 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 25 8.2E-5 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site TSC_c08500 e1316435ec548aebd841f02870d1818e 145 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 25 2.6E-7 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site TSC_c08500 e1316435ec548aebd841f02870d1818e 145 PRINTS PR00813 Bacterial general secretion pathway protein G signature 6 31 6.8E-5 T 12-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 TSC_c08500 e1316435ec548aebd841f02870d1818e 145 PRINTS PR00813 Bacterial general secretion pathway protein G signature 43 61 6.8E-5 T 12-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 TSC_c00920 8190617a3bbdb8f7f12b4921aca86c16 337 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 160 208 - T 12-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00920 8190617a3bbdb8f7f12b4921aca86c16 337 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 29 224 6.8E-71 T 12-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00920 8190617a3bbdb8f7f12b4921aca86c16 337 Gene3D G3DSA:2.60.40.2600 113 337 7.6E-89 T 12-10-2018 TSC_c00920 8190617a3bbdb8f7f12b4921aca86c16 337 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 28 98 8.4E-9 T 12-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00920 8190617a3bbdb8f7f12b4921aca86c16 337 SUPERFAMILY SSF49503 111 262 6.53E-51 T 12-10-2018 IPR008972 Cupredoxin TSC_c00920 8190617a3bbdb8f7f12b4921aca86c16 337 SUPERFAMILY SSF81464 23 109 1.64E-18 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00920 8190617a3bbdb8f7f12b4921aca86c16 337 Gene3D G3DSA:1.10.287.90 19 111 2.1E-33 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00920 8190617a3bbdb8f7f12b4921aca86c16 337 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 139 209 2.0E-18 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00920 8190617a3bbdb8f7f12b4921aca86c16 337 Pfam PF00034 Cytochrome c 237 325 2.5E-10 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00920 8190617a3bbdb8f7f12b4921aca86c16 337 SUPERFAMILY SSF46626 237 324 4.07E-19 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c05600 b9878faa4fd7b61612390b8d2f3a8d6d 139 Gene3D G3DSA:1.20.1550.10 3 125 5.6E-8 T 12-10-2018 IPR023380 DsbB-like superfamily TSC_c05600 b9878faa4fd7b61612390b8d2f3a8d6d 139 Pfam PF02600 Disulfide bond formation protein DsbB 11 110 7.3E-9 T 12-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 TSC_c05600 b9878faa4fd7b61612390b8d2f3a8d6d 139 SUPERFAMILY SSF158442 12 129 1.44E-24 T 12-10-2018 IPR023380 DsbB-like superfamily TSC_c05600 b9878faa4fd7b61612390b8d2f3a8d6d 139 PIRSF PIRSF036659 2 138 3.3E-39 T 12-10-2018 IPR012187 Disulphide bond formation protein BdbC TSC_c21520 96b842b9374d660573e5de47e9ac49b4 437 Gene3D G3DSA:3.80.30.20 138 366 2.7E-68 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TSC_c21520 96b842b9374d660573e5de47e9ac49b4 437 SMART SM00729 141 358 5.7E-43 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSC_c21520 96b842b9374d660573e5de47e9ac49b4 437 Pfam PF04055 Radical SAM superfamily 147 313 1.2E-21 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSC_c21520 96b842b9374d660573e5de47e9ac49b4 437 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 145 165 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 TSC_c21520 96b842b9374d660573e5de47e9ac49b4 437 Pfam PF00919 Uncharacterized protein family UPF0004 5 92 4.3E-23 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 TSC_c21520 96b842b9374d660573e5de47e9ac49b4 437 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 6 420 1.1E-98 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 TSC_c21520 96b842b9374d660573e5de47e9ac49b4 437 Gene3D G3DSA:3.40.50.12160 4 123 1.2E-19 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily TSC_c21520 96b842b9374d660573e5de47e9ac49b4 437 SUPERFAMILY SSF102114 120 358 8.11E-50 T 12-10-2018 TSC_c17510 97352469f919c2059715aa2b77298469 1196 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 32 50 - T 12-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 TSC_c17510 97352469f919c2059715aa2b77298469 1196 SUPERFAMILY SSF53706 9 1030 0.0 T 12-10-2018 TSC_c17510 97352469f919c2059715aa2b77298469 1196 SUPERFAMILY SSF50692 1049 1191 3.84E-44 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSC_c17510 97352469f919c2059715aa2b77298469 1196 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1087 1114 - T 12-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 TSC_c17510 97352469f919c2059715aa2b77298469 1196 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 12 1192 0.0 T 12-10-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 TSC_c17510 97352469f919c2059715aa2b77298469 1196 Pfam PF01568 Molydopterin dinucleotide binding domain 1049 1164 6.3E-22 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSC_c17510 97352469f919c2059715aa2b77298469 1196 Gene3D G3DSA:3.40.50.12440 28 1196 0.0 T 12-10-2018 TSC_c17510 97352469f919c2059715aa2b77298469 1196 Pfam PF00384 Molybdopterin oxidoreductase 92 798 1.4E-124 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c17510 97352469f919c2059715aa2b77298469 1196 SMART SM00926 27 89 4.3E-4 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c10920 da7f2b41607e7f69a15dca7be4ee3879 172 Gene3D G3DSA:2.40.128.110 20 171 2.3E-22 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily TSC_c10920 da7f2b41607e7f69a15dca7be4ee3879 172 Pfam PF04264 YceI-like domain 37 166 2.1E-15 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TSC_c10920 da7f2b41607e7f69a15dca7be4ee3879 172 SMART SM00867 18 170 3.1E-8 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TSC_c10920 da7f2b41607e7f69a15dca7be4ee3879 172 SUPERFAMILY SSF101874 30 169 1.57E-20 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily TSC_c21880 8478c7106c3e00806d1fda3243ce20e2 391 Gene3D G3DSA:3.30.450.40 61 246 1.9E-16 T 12-10-2018 IPR029016 GAF-like domain superfamily TSC_c21880 8478c7106c3e00806d1fda3243ce20e2 391 Gene3D G3DSA:3.30.70.270 247 391 2.0E-36 T 12-10-2018 TSC_c21880 8478c7106c3e00806d1fda3243ce20e2 391 SMART SM00267 237 388 2.0E-26 T 12-10-2018 IPR000160 GGDEF domain TSC_c21880 8478c7106c3e00806d1fda3243ce20e2 391 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 244 389 1.6E-28 T 12-10-2018 IPR000160 GGDEF domain TSC_c21880 8478c7106c3e00806d1fda3243ce20e2 391 SUPERFAMILY SSF55073 253 389 5.49E-32 T 12-10-2018 IPR029787 Nucleotide cyclase TSC_c21880 8478c7106c3e00806d1fda3243ce20e2 391 Pfam PF00990 Diguanylate cyclase, GGDEF domain 248 389 3.6E-29 T 12-10-2018 IPR000160 GGDEF domain TSC_c21880 8478c7106c3e00806d1fda3243ce20e2 391 SUPERFAMILY SSF55781 63 235 3.05E-11 T 12-10-2018 TSC_c17900 f32c221ecd57a4a3c7492e98145caa83 161 Gene3D G3DSA:3.40.1520.10 1 161 5.6E-75 T 12-10-2018 IPR036902 Ta1353-like superfamily TSC_c17900 f32c221ecd57a4a3c7492e98145caa83 161 SUPERFAMILY SSF103165 1 161 7.06E-70 T 12-10-2018 IPR036902 Ta1353-like superfamily TSC_c17900 f32c221ecd57a4a3c7492e98145caa83 161 Pfam PF04008 Adenosine specific kinase 6 160 1.1E-70 T 12-10-2018 IPR007153 Adenosine specific kinase TSC_c14590 ec368702a6c538836b674e2c9fb01494 562 SUPERFAMILY SSF55874 432 558 1.31E-18 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c14590 ec368702a6c538836b674e2c9fb01494 562 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 471 559 7.5E-6 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c14590 ec368702a6c538836b674e2c9fb01494 562 Pfam PF07730 Histidine kinase 373 430 1.9E-12 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TSC_c14590 ec368702a6c538836b674e2c9fb01494 562 SMART SM00387 467 560 8.9E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c14590 ec368702a6c538836b674e2c9fb01494 562 Gene3D G3DSA:3.30.565.10 428 560 9.3E-29 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c06900 731851e33bf12b60e18287b40227d18a 438 PIRSF PIRSF006815 1 437 1.4E-156 T 12-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 TSC_c06900 731851e33bf12b60e18287b40227d18a 438 SUPERFAMILY SSF53383 1 437 1.83E-116 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c06900 731851e33bf12b60e18287b40227d18a 438 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 1 436 42.72 T 12-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 TSC_c06900 731851e33bf12b60e18287b40227d18a 438 Gene3D G3DSA:3.90.1150.10 68 432 5.0E-154 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c06900 731851e33bf12b60e18287b40227d18a 438 Pfam PF02347 Glycine cleavage system P-protein 3 429 1.3E-118 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TSC_c06900 731851e33bf12b60e18287b40227d18a 438 Gene3D G3DSA:3.40.640.10 79 340 5.0E-154 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c22050 d7550f3bbd7248a4f3dadd6753c5f8c5 424 Gene3D G3DSA:3.40.50.10860 49 188 1.2E-64 T 12-10-2018 TSC_c22050 d7550f3bbd7248a4f3dadd6753c5f8c5 424 SUPERFAMILY SSF53223 14 191 6.08E-70 T 12-10-2018 TSC_c22050 d7550f3bbd7248a4f3dadd6753c5f8c5 424 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 108 121 - T 12-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSC_c22050 d7550f3bbd7248a4f3dadd6753c5f8c5 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 180 202 1.6E-32 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSC_c22050 d7550f3bbd7248a4f3dadd6753c5f8c5 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 349 360 1.6E-32 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSC_c22050 d7550f3bbd7248a4f3dadd6753c5f8c5 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 100 114 1.6E-32 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSC_c22050 d7550f3bbd7248a4f3dadd6753c5f8c5 424 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 222 242 1.6E-32 T 12-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSC_c22050 d7550f3bbd7248a4f3dadd6753c5f8c5 424 PIRSF PIRSF000185 14 424 7.9E-162 T 12-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 TSC_c22050 d7550f3bbd7248a4f3dadd6753c5f8c5 424 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 43 171 7.2E-56 T 12-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSC_c22050 d7550f3bbd7248a4f3dadd6753c5f8c5 424 SUPERFAMILY SSF51735 189 423 1.05E-77 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c22050 d7550f3bbd7248a4f3dadd6753c5f8c5 424 Gene3D G3DSA:1.10.8.1210 4 48 2.4E-17 T 12-10-2018 TSC_c22050 d7550f3bbd7248a4f3dadd6753c5f8c5 424 Gene3D G3DSA:3.40.50.720 189 424 1.4E-88 T 12-10-2018 TSC_c22050 d7550f3bbd7248a4f3dadd6753c5f8c5 424 SMART SM00839 191 421 9.1E-101 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSC_c22050 d7550f3bbd7248a4f3dadd6753c5f8c5 424 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 189 421 7.5E-74 T 12-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 TSC_c13940 243d17cfc379666cf2d782c4760a7ac5 178 Pfam PF01936 NYN domain 10 162 1.1E-34 T 12-10-2018 IPR021139 NYN domain, limkain-b1-type TSC_c13940 243d17cfc379666cf2d782c4760a7ac5 178 Gene3D G3DSA:3.40.50.1010 3 166 4.1E-46 T 12-10-2018 TSC_c12650 be69860c329f34d854feabfcfc091eb7 477 SUPERFAMILY SSF53720 9 476 1.31E-164 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSC_c12650 be69860c329f34d854feabfcfc091eb7 477 Gene3D G3DSA:3.40.605.10 22 468 2.4E-174 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSC_c12650 be69860c329f34d854feabfcfc091eb7 477 Pfam PF00171 Aldehyde dehydrogenase family 23 472 2.2E-166 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSC_c12650 be69860c329f34d854feabfcfc091eb7 477 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 280 291 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TSC_c12650 be69860c329f34d854feabfcfc091eb7 477 Gene3D G3DSA:3.40.309.10 259 445 2.4E-174 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSC_c01410 1c93cd387e065df3aebeaaaec35573cf 522 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 300 417 4.2E-27 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c01410 1c93cd387e065df3aebeaaaec35573cf 522 SUPERFAMILY SSF53738 285 425 3.81E-32 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c01410 1c93cd387e065df3aebeaaaec35573cf 522 SUPERFAMILY SSF53738 189 297 4.71E-10 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c01410 1c93cd387e065df3aebeaaaec35573cf 522 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 122 131 - T 12-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c01410 1c93cd387e065df3aebeaaaec35573cf 522 Gene3D G3DSA:3.40.120.10 201 298 3.2E-45 T 12-10-2018 TSC_c01410 1c93cd387e065df3aebeaaaec35573cf 522 Gene3D G3DSA:3.40.120.10 1 200 1.1E-73 T 12-10-2018 TSC_c01410 1c93cd387e065df3aebeaaaec35573cf 522 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 454 516 5.6E-10 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c01410 1c93cd387e065df3aebeaaaec35573cf 522 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 191 297 1.1E-15 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c01410 1c93cd387e065df3aebeaaaec35573cf 522 Gene3D G3DSA:3.30.310.50 421 522 5.5E-30 T 12-10-2018 TSC_c01410 1c93cd387e065df3aebeaaaec35573cf 522 SUPERFAMILY SSF53738 10 215 2.59E-46 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c01410 1c93cd387e065df3aebeaaaec35573cf 522 Gene3D G3DSA:3.40.120.10 299 420 2.1E-35 T 12-10-2018 TSC_c01410 1c93cd387e065df3aebeaaaec35573cf 522 SUPERFAMILY SSF55957 411 521 2.09E-18 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c01410 1c93cd387e065df3aebeaaaec35573cf 522 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 24 161 9.9E-34 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 Pfam PF00702 haloacid dehalogenase-like hydrolase 359 573 1.0E-46 T 12-10-2018 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 100 667 9.2E-182 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 361 375 5.3E-25 T 12-10-2018 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 559 578 5.3E-25 T 12-10-2018 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 211 225 5.3E-25 T 12-10-2018 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 507 517 5.3E-25 T 12-10-2018 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 582 594 5.3E-25 T 12-10-2018 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 Gene3D G3DSA:2.70.150.20 154 266 1.7E-39 T 12-10-2018 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 363 369 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 SUPERFAMILY SSF81653 163 261 6.41E-29 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 Pfam PF00122 E1-E2 ATPase 161 340 2.6E-53 T 12-10-2018 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 SUPERFAMILY SSF81665 110 640 1.31E-11 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 PRINTS PR00943 Copper-transporting ATPase signature 85 104 8.0E-8 T 12-10-2018 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 PRINTS PR00943 Copper-transporting ATPase signature 537 554 8.0E-8 T 12-10-2018 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 PRINTS PR00943 Copper-transporting ATPase signature 632 646 8.0E-8 T 12-10-2018 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 PRINTS PR00943 Copper-transporting ATPase signature 151 169 8.0E-8 T 12-10-2018 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 137 637 4.1E-85 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 Gene3D G3DSA:3.40.50.1000 342 611 8.6E-91 T 12-10-2018 IPR023214 HAD superfamily TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 SUPERFAMILY SSF56784 360 665 3.41E-58 T 12-10-2018 IPR036412 HAD-like superfamily TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 82 668 1.7E-177 T 12-10-2018 TSC_c03730 b1124e767428e5d72441e4d09f9ddff6 674 Gene3D G3DSA:3.40.1110.10 372 492 8.6E-91 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TSC_c08960 91e946ccaa5d932eb6102d7b050d57da 307 SMART SM00267 160 307 3.3E-15 T 12-10-2018 IPR000160 GGDEF domain TSC_c08960 91e946ccaa5d932eb6102d7b050d57da 307 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 168 261 2.2E-23 T 12-10-2018 IPR000160 GGDEF domain TSC_c08960 91e946ccaa5d932eb6102d7b050d57da 307 Pfam PF00990 Diguanylate cyclase, GGDEF domain 171 262 4.0E-22 T 12-10-2018 IPR000160 GGDEF domain TSC_c08960 91e946ccaa5d932eb6102d7b050d57da 307 Gene3D G3DSA:3.30.70.270 157 307 1.1E-29 T 12-10-2018 TSC_c08960 91e946ccaa5d932eb6102d7b050d57da 307 SUPERFAMILY SSF55073 176 306 4.94E-26 T 12-10-2018 IPR029787 Nucleotide cyclase TSC_c12260 3f4bd39f64ff13b770d1e11ee85b16ab 286 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 18 281 2.6E-101 T 12-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 TSC_c12260 3f4bd39f64ff13b770d1e11ee85b16ab 286 SUPERFAMILY SSF54675 14 116 1.57E-32 T 12-10-2018 TSC_c12260 3f4bd39f64ff13b770d1e11ee85b16ab 286 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 117 281 2.7E-60 T 12-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 TSC_c12260 3f4bd39f64ff13b770d1e11ee85b16ab 286 Gene3D G3DSA:3.20.20.70 131 273 2.5E-114 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c12260 3f4bd39f64ff13b770d1e11ee85b16ab 286 SUPERFAMILY SSF51690 117 281 1.77E-59 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TSC_c12260 3f4bd39f64ff13b770d1e11ee85b16ab 286 Gene3D G3DSA:3.90.1170.20 21 281 2.5E-114 T 12-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 TSC_c12260 3f4bd39f64ff13b770d1e11ee85b16ab 286 PIRSF PIRSF006250 12 285 1.2E-96 T 12-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 TSC_c12260 3f4bd39f64ff13b770d1e11ee85b16ab 286 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 27 115 8.7E-27 T 12-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 TSC_c15560 450a7f8045176e18add0eff18c386790 397 Gene3D G3DSA:3.10.350.10 34 97 3.3E-14 T 12-10-2018 IPR036779 LysM domain superfamily TSC_c15560 450a7f8045176e18add0eff18c386790 397 Gene3D G3DSA:3.10.350.10 103 154 7.7E-14 T 12-10-2018 IPR036779 LysM domain superfamily TSC_c15560 450a7f8045176e18add0eff18c386790 397 Pfam PF01476 LysM domain 162 198 0.0012 T 12-10-2018 IPR018392 LysM domain TSC_c15560 450a7f8045176e18add0eff18c386790 397 Pfam PF01476 LysM domain 46 88 6.8E-11 T 12-10-2018 IPR018392 LysM domain TSC_c15560 450a7f8045176e18add0eff18c386790 397 Pfam PF01476 LysM domain 106 150 7.0E-10 T 12-10-2018 IPR018392 LysM domain TSC_c15560 450a7f8045176e18add0eff18c386790 397 SMART SM00257 45 88 9.0E-9 T 12-10-2018 IPR018392 LysM domain TSC_c15560 450a7f8045176e18add0eff18c386790 397 SMART SM00257 157 201 0.63 T 12-10-2018 IPR018392 LysM domain TSC_c15560 450a7f8045176e18add0eff18c386790 397 SMART SM00257 105 150 1.9E-10 T 12-10-2018 IPR018392 LysM domain TSC_c15560 450a7f8045176e18add0eff18c386790 397 Pfam PF01551 Peptidase family M23 296 392 2.2E-34 T 12-10-2018 IPR016047 Peptidase M23 TSC_c15560 450a7f8045176e18add0eff18c386790 397 Gene3D G3DSA:2.70.70.10 230 397 4.4E-50 T 12-10-2018 IPR011055 Duplicated hybrid motif TSC_c15560 450a7f8045176e18add0eff18c386790 397 Gene3D G3DSA:3.10.350.10 155 201 7.7E-14 T 12-10-2018 IPR036779 LysM domain superfamily TSC_c15560 450a7f8045176e18add0eff18c386790 397 SUPERFAMILY SSF51261 213 396 7.32E-58 T 12-10-2018 IPR011055 Duplicated hybrid motif TSC_c15560 450a7f8045176e18add0eff18c386790 397 SUPERFAMILY SSF54106 43 88 8.5E-10 T 12-10-2018 TSC_c15560 450a7f8045176e18add0eff18c386790 397 SUPERFAMILY SSF54106 105 150 4.32E-9 T 12-10-2018 TSC_c01340 31e04e571fbf5a35fbb47b1628a5bea3 519 SUPERFAMILY SSF53474 26 510 7.64E-98 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c01340 31e04e571fbf5a35fbb47b1628a5bea3 519 Pfam PF00135 Carboxylesterase family 27 499 1.6E-86 T 12-10-2018 IPR002018 Carboxylesterase, type B TSC_c01340 31e04e571fbf5a35fbb47b1628a5bea3 519 Gene3D G3DSA:3.40.50.1820 20 510 2.2E-118 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c01340 31e04e571fbf5a35fbb47b1628a5bea3 519 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 196 211 - T 12-10-2018 IPR019826 Carboxylesterase type B, active site TSC_c13200 56dcefcbb2ebce0569c39986f3bc274d 763 Pfam PF00378 Enoyl-CoA hydratase/isomerase 458 593 4.3E-12 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSC_c13200 56dcefcbb2ebce0569c39986f3bc274d 763 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 185 1.4E-48 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TSC_c13200 56dcefcbb2ebce0569c39986f3bc274d 763 Gene3D G3DSA:3.90.226.10 449 760 6.7E-28 T 12-10-2018 TSC_c13200 56dcefcbb2ebce0569c39986f3bc274d 763 SUPERFAMILY SSF51735 1 187 1.8E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c13200 56dcefcbb2ebce0569c39986f3bc274d 763 SUPERFAMILY SSF52096 451 759 6.63E-35 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSC_c13200 56dcefcbb2ebce0569c39986f3bc274d 763 Gene3D G3DSA:3.40.50.720 1 189 1.0E-57 T 12-10-2018 TSC_c13200 56dcefcbb2ebce0569c39986f3bc274d 763 Gene3D G3DSA:1.10.1040.10 190 300 8.4E-21 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSC_c13200 56dcefcbb2ebce0569c39986f3bc274d 763 SUPERFAMILY SSF48179 187 303 1.02E-25 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSC_c13200 56dcefcbb2ebce0569c39986f3bc274d 763 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 283 4.2E-17 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TSC_c13200 56dcefcbb2ebce0569c39986f3bc274d 763 SUPERFAMILY SSF48179 333 393 1.45E-6 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSC_c17120 7af80d8f7d98d0821359d79e2d17b63e 1063 Pfam PF08298 PrkA AAA domain 718 797 4.3E-20 T 12-10-2018 IPR013153 PrkA AAA domain TSC_c17120 7af80d8f7d98d0821359d79e2d17b63e 1063 Pfam PF08298 PrkA AAA domain 24 331 2.4E-63 T 12-10-2018 IPR013153 PrkA AAA domain TSC_c17120 7af80d8f7d98d0821359d79e2d17b63e 1063 SMART SM00763 23 799 2.8E-155 T 12-10-2018 IPR013153 PrkA AAA domain TSC_c17120 7af80d8f7d98d0821359d79e2d17b63e 1063 Gene3D G3DSA:3.10.28.10 502 675 1.7E-15 T 12-10-2018 IPR027434 Homing endonuclease TSC_c17120 7af80d8f7d98d0821359d79e2d17b63e 1063 Gene3D G3DSA:2.170.16.10 349 429 1.1E-5 T 12-10-2018 TSC_c17120 7af80d8f7d98d0821359d79e2d17b63e 1063 Pfam PF06798 PrkA serine protein kinase C-terminal domain 803 1053 1.5E-86 T 12-10-2018 IPR010650 PrkA C-terminal domain TSC_c17120 7af80d8f7d98d0821359d79e2d17b63e 1063 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 700 724 1.6E-4 T 12-10-2018 IPR030934 Intein C-terminal splicing region TSC_c17120 7af80d8f7d98d0821359d79e2d17b63e 1063 SUPERFAMILY SSF52540 80 310 1.41E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c17120 7af80d8f7d98d0821359d79e2d17b63e 1063 SUPERFAMILY SSF51294 331 725 7.32E-13 T 12-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 TSC_c24700 9e8957f0aee4db65cbe7ffa9496b9abe 260 Pfam PF03631 Virulence factor BrkB 12 259 1.7E-31 T 12-10-2018 IPR017039 Virulence factor BrkB TSC_c24700 9e8957f0aee4db65cbe7ffa9496b9abe 260 PIRSF PIRSF035875 1 260 3.7E-34 T 12-10-2018 IPR017039 Virulence factor BrkB TSC_c10610 14fa21f8a40b8dcca1964457d8778a08 433 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 422 1.5E-86 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSC_c10610 14fa21f8a40b8dcca1964457d8778a08 433 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 427 2.3E-105 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSC_c10610 14fa21f8a40b8dcca1964457d8778a08 433 PIRSF PIRSF006066 5 432 9.0E-94 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSC_c22870 a66640d8607013dc1ef2ff62a2f32060 354 TIGRFAM TIGR01801 CM_A: chorismate mutase 4 101 6.8E-34 T 12-10-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TSC_c22870 a66640d8607013dc1ef2ff62a2f32060 354 SUPERFAMILY SSF48600 5 87 8.55E-21 T 12-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TSC_c22870 a66640d8607013dc1ef2ff62a2f32060 354 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 94 348 4.5E-122 T 12-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 TSC_c22870 a66640d8607013dc1ef2ff62a2f32060 354 SUPERFAMILY SSF51569 65 349 2.01E-98 T 12-10-2018 TSC_c22870 a66640d8607013dc1ef2ff62a2f32060 354 Pfam PF01817 Chorismate mutase type II 9 86 1.6E-21 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TSC_c22870 a66640d8607013dc1ef2ff62a2f32060 354 SMART SM00830 9 88 3.5E-29 T 12-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TSC_c22870 a66640d8607013dc1ef2ff62a2f32060 354 Gene3D G3DSA:3.20.20.70 93 352 3.9E-100 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c22870 a66640d8607013dc1ef2ff62a2f32060 354 Pfam PF00793 DAHP synthetase I family 114 349 1.2E-82 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 TSC_c22870 a66640d8607013dc1ef2ff62a2f32060 354 Gene3D G3DSA:1.20.59.10 1 90 2.3E-30 T 12-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TSC_c14670 3df90c00930ea158b1d539edaa12324c 287 SUPERFAMILY SSF51735 1 248 1.6E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c14670 3df90c00930ea158b1d539edaa12324c 287 Gene3D G3DSA:3.40.50.720 2 281 1.2E-49 T 12-10-2018 TSC_c14670 3df90c00930ea158b1d539edaa12324c 287 Pfam PF13460 NAD(P)H-binding 7 140 3.9E-16 T 12-10-2018 IPR016040 NAD(P)-binding domain TSC_c03820 0c70e66397c4c403c4318152bee8007f 373 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 256 366 7.0E-31 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c03820 0c70e66397c4c403c4318152bee8007f 373 SMART SM00388 146 209 9.3E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c03820 0c70e66397c4c403c4318152bee8007f 373 Pfam PF00512 His Kinase A (phospho-acceptor) domain 146 209 1.2E-13 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c03820 0c70e66397c4c403c4318152bee8007f 373 Gene3D G3DSA:1.10.287.130 94 201 3.6E-23 T 12-10-2018 TSC_c03820 0c70e66397c4c403c4318152bee8007f 373 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 364 6.1E-21 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c03820 0c70e66397c4c403c4318152bee8007f 373 PRINTS PR00344 Bacterial sensor protein C-terminal signature 310 320 6.1E-21 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c03820 0c70e66397c4c403c4318152bee8007f 373 PRINTS PR00344 Bacterial sensor protein C-terminal signature 292 306 6.1E-21 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c03820 0c70e66397c4c403c4318152bee8007f 373 PRINTS PR00344 Bacterial sensor protein C-terminal signature 327 345 6.1E-21 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c03820 0c70e66397c4c403c4318152bee8007f 373 SUPERFAMILY SSF47384 130 209 9.02E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSC_c03820 0c70e66397c4c403c4318152bee8007f 373 Gene3D G3DSA:3.30.565.10 208 367 3.2E-53 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c03820 0c70e66397c4c403c4318152bee8007f 373 SMART SM00304 93 145 1.0E-8 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSC_c03820 0c70e66397c4c403c4318152bee8007f 373 Pfam PF00672 HAMP domain 100 142 4.9E-7 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSC_c03820 0c70e66397c4c403c4318152bee8007f 373 SUPERFAMILY SSF55874 199 365 1.83E-52 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c03820 0c70e66397c4c403c4318152bee8007f 373 SMART SM00387 255 367 5.4E-45 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c12750 673ab1e039a0fc00ba70cc5c51747d8b 515 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 151 249 7.8E-16 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSC_c12750 673ab1e039a0fc00ba70cc5c51747d8b 515 SUPERFAMILY SSF56645 83 267 1.96E-30 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSC_c12750 673ab1e039a0fc00ba70cc5c51747d8b 515 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 378 397 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSC_c12750 673ab1e039a0fc00ba70cc5c51747d8b 515 Gene3D G3DSA:1.20.140.10 256 426 7.0E-34 T 12-10-2018 TSC_c12750 673ab1e039a0fc00ba70cc5c51747d8b 515 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 261 419 2.8E-35 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSC_c12750 673ab1e039a0fc00ba70cc5c51747d8b 515 SUPERFAMILY SSF47203 260 428 6.28E-34 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSC_c12750 673ab1e039a0fc00ba70cc5c51747d8b 515 Gene3D G3DSA:2.40.110.20 114 255 4.5E-26 T 12-10-2018 TSC_c22410 f389491f81b27f082d040cccd5e6af6e 276 SUPERFAMILY SSF50249 2 125 6.51E-55 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c22410 f389491f81b27f082d040cccd5e6af6e 276 Gene3D G3DSA:4.10.950.10 197 276 2.2E-36 T 12-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22410 f389491f81b27f082d040cccd5e6af6e 276 Gene3D G3DSA:2.40.50.140 1 115 1.9E-53 T 12-10-2018 TSC_c22410 f389491f81b27f082d040cccd5e6af6e 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 2.7E-54 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TSC_c22410 f389491f81b27f082d040cccd5e6af6e 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 2.5E-34 T 12-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22410 f389491f81b27f082d040cccd5e6af6e 276 SMART SM01382 125 253 2.1E-85 T 12-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 TSC_c22410 f389491f81b27f082d040cccd5e6af6e 276 SMART SM01383 42 119 2.9E-47 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22410 f389491f81b27f082d040cccd5e6af6e 276 Gene3D G3DSA:2.30.30.30 119 196 2.3E-31 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 TSC_c22410 f389491f81b27f082d040cccd5e6af6e 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 48.917 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 TSC_c22410 f389491f81b27f082d040cccd5e6af6e 276 PIRSF PIRSF002158 3 276 7.9E-105 T 12-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22410 f389491f81b27f082d040cccd5e6af6e 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 276 4.8E-137 T 12-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 TSC_c22410 f389491f81b27f082d040cccd5e6af6e 276 SUPERFAMILY SSF50104 127 272 1.99E-59 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily TSC_c22410 f389491f81b27f082d040cccd5e6af6e 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 12-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c03180 44b3ef97f292866bf1e7c8689761873d 172 SUPERFAMILY SSF52980 6 158 8.04E-20 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSC_c03180 44b3ef97f292866bf1e7c8689761873d 172 Gene3D G3DSA:3.90.1570.10 2 164 3.1E-15 T 12-10-2018 TSC_c03180 44b3ef97f292866bf1e7c8689761873d 172 Pfam PF05685 Putative restriction endonuclease 10 170 2.3E-32 T 12-10-2018 IPR008538 Domain of unknown function DUF820 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 SUPERFAMILY SSF81665 78 593 5.49E-14 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 Gene3D G3DSA:3.40.1110.10 323 437 3.6E-84 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 84 583 1.0E-92 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 SUPERFAMILY SSF56784 310 612 6.31E-56 T 12-10-2018 IPR036412 HAD-like superfamily TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 Gene3D G3DSA:3.40.50.1000 307 555 3.6E-84 T 12-10-2018 IPR023214 HAD superfamily TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 SUPERFAMILY SSF81653 115 212 2.09E-29 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 26 615 2.4E-175 T 12-10-2018 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 430 441 9.8E-28 T 12-10-2018 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 162 176 9.8E-28 T 12-10-2018 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 312 326 9.8E-28 T 12-10-2018 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 452 462 9.8E-28 T 12-10-2018 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 505 524 9.8E-28 T 12-10-2018 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 528 540 9.8E-28 T 12-10-2018 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 PRINTS PR00943 Copper-transporting ATPase signature 235 249 9.6E-15 T 12-10-2018 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 PRINTS PR00943 Copper-transporting ATPase signature 482 499 9.6E-15 T 12-10-2018 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 PRINTS PR00943 Copper-transporting ATPase signature 10 28 9.6E-15 T 12-10-2018 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 PRINTS PR00943 Copper-transporting ATPase signature 30 49 9.6E-15 T 12-10-2018 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 PRINTS PR00943 Copper-transporting ATPase signature 102 120 9.6E-15 T 12-10-2018 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 PRINTS PR00943 Copper-transporting ATPase signature 82 101 9.6E-15 T 12-10-2018 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 79 614 1.2E-117 T 12-10-2018 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 ProSitePatterns PS01229 Hypothetical cof family signature 2. 505 527 - T 12-10-2018 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 Gene3D G3DSA:2.70.150.20 105 217 2.1E-41 T 12-10-2018 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 314 320 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 Pfam PF00122 E1-E2 ATPase 113 290 3.0E-57 T 12-10-2018 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 45 614 1.4E-179 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TSC_c03850 448fb29d505cdbb46cf198a47a0dba55 625 Pfam PF00702 haloacid dehalogenase-like hydrolase 309 519 3.8E-51 T 12-10-2018 TSC_c02180 1bcbafa53d3b4f1a827bc37cfdea5677 375 SUPERFAMILY SSF51735 139 317 1.08E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c02180 1bcbafa53d3b4f1a827bc37cfdea5677 375 SMART SM01002 148 310 1.5E-73 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TSC_c02180 1bcbafa53d3b4f1a827bc37cfdea5677 375 SMART SM01003 5 139 9.4E-64 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TSC_c02180 1bcbafa53d3b4f1a827bc37cfdea5677 375 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 12-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 TSC_c02180 1bcbafa53d3b4f1a827bc37cfdea5677 375 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 143 365 4.1E-65 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TSC_c02180 1bcbafa53d3b4f1a827bc37cfdea5677 375 Gene3D G3DSA:3.40.50.720 139 317 1.1E-142 T 12-10-2018 TSC_c02180 1bcbafa53d3b4f1a827bc37cfdea5677 375 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 6 139 3.3E-44 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TSC_c02180 1bcbafa53d3b4f1a827bc37cfdea5677 375 SUPERFAMILY SSF52283 3 170 1.96E-50 T 12-10-2018 TSC_c02180 1bcbafa53d3b4f1a827bc37cfdea5677 375 Gene3D G3DSA:3.40.50.720 6 353 1.1E-142 T 12-10-2018 TSC_c20550 3603751fd2addfb51ffc38898e67395d 258 SUPERFAMILY SSF56112 8 253 8.79E-56 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TSC_c20550 3603751fd2addfb51ffc38898e67395d 258 Gene3D G3DSA:1.10.510.10 7 256 3.3E-53 T 12-10-2018 TSC_c20550 3603751fd2addfb51ffc38898e67395d 258 SMART SM00220 15 257 6.3E-37 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TSC_c20550 3603751fd2addfb51ffc38898e67395d 258 Pfam PF00069 Protein kinase domain 15 252 1.3E-34 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TSC_c20550 3603751fd2addfb51ffc38898e67395d 258 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 125 137 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TSC_c18470 23f3384e4aca0306a1950bea09ea7a3e 440 Pfam PF00919 Uncharacterized protein family UPF0004 2 100 4.5E-25 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 TSC_c18470 23f3384e4aca0306a1950bea09ea7a3e 440 Pfam PF04055 Radical SAM superfamily 142 312 2.4E-33 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSC_c18470 23f3384e4aca0306a1950bea09ea7a3e 440 SUPERFAMILY SSF102114 105 365 8.63E-67 T 12-10-2018 TSC_c18470 23f3384e4aca0306a1950bea09ea7a3e 440 SMART SM00729 138 355 1.3E-62 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSC_c18470 23f3384e4aca0306a1950bea09ea7a3e 440 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 2 423 4.6E-143 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 TSC_c18470 23f3384e4aca0306a1950bea09ea7a3e 440 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 1 427 64.841 T 12-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 TSC_c18470 23f3384e4aca0306a1950bea09ea7a3e 440 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 427 2.1E-133 T 12-10-2018 TSC_c18470 23f3384e4aca0306a1950bea09ea7a3e 440 Gene3D G3DSA:3.80.30.20 137 369 9.9E-87 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TSC_c18470 23f3384e4aca0306a1950bea09ea7a3e 440 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 142 162 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 TSC_c18470 23f3384e4aca0306a1950bea09ea7a3e 440 Gene3D G3DSA:3.40.50.12160 1 127 7.2E-27 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily TSC_c08330 a3f8b280f3b2e0da1c0ec63cc74cb4ee 552 Pfam PF02660 Glycerol-3-phosphate acyltransferase 7 186 4.4E-25 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TSC_c08330 a3f8b280f3b2e0da1c0ec63cc74cb4ee 552 SUPERFAMILY SSF51735 351 478 3.02E-16 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c08330 a3f8b280f3b2e0da1c0ec63cc74cb4ee 552 SMART SM01207 6 187 6.2E-21 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TSC_c08330 a3f8b280f3b2e0da1c0ec63cc74cb4ee 552 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 361 481 6.1E-9 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase TSC_c08330 a3f8b280f3b2e0da1c0ec63cc74cb4ee 552 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 3 195 12.66 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TSC_c08330 a3f8b280f3b2e0da1c0ec63cc74cb4ee 552 Gene3D G3DSA:3.40.50.720 347 487 1.2E-17 T 12-10-2018 TSC_c08330 a3f8b280f3b2e0da1c0ec63cc74cb4ee 552 PIRSF PIRSF026478 1 552 0.0 T 12-10-2018 IPR021194 Uncharacterised protein family, dehydrogenase DR0790 type, predicted TSC_c17660 303e70ae78107642eb8757934279a6f3 139 Pfam PF02082 Transcriptional regulator 7 81 5.3E-21 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type TSC_c17660 303e70ae78107642eb8757934279a6f3 139 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 6 132 9.9E-27 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type TSC_c17660 303e70ae78107642eb8757934279a6f3 139 SUPERFAMILY SSF46785 10 132 2.6E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c17660 303e70ae78107642eb8757934279a6f3 139 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 48 66 - T 12-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site TSC_c17660 303e70ae78107642eb8757934279a6f3 139 Gene3D G3DSA:1.10.10.10 4 139 4.8E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c03080 8200f649750c501be541a75620fa084f 417 Hamap MF_01454 GTPase Obg [obg]. 1 326 45.709 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 TSC_c03080 8200f649750c501be541a75620fa084f 417 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 158 317 6.2E-12 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSC_c03080 8200f649750c501be541a75620fa084f 417 Pfam PF09269 Domain of unknown function (DUF1967) 350 414 7.3E-17 T 12-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 TSC_c03080 8200f649750c501be541a75620fa084f 417 Gene3D G3DSA:2.70.210.12 1 154 6.6E-61 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily TSC_c03080 8200f649750c501be541a75620fa084f 417 Pfam PF01018 GTP1/OBG 4 155 3.9E-56 T 12-10-2018 IPR006169 GTP1/OBG domain TSC_c03080 8200f649750c501be541a75620fa084f 417 SUPERFAMILY SSF102741 344 416 2.35E-15 T 12-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily TSC_c03080 8200f649750c501be541a75620fa084f 417 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 325 2.4E-128 T 12-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 TSC_c03080 8200f649750c501be541a75620fa084f 417 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 12-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 TSC_c03080 8200f649750c501be541a75620fa084f 417 Gene3D G3DSA:2.40.240.60 344 417 6.4E-26 T 12-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily TSC_c03080 8200f649750c501be541a75620fa084f 417 Pfam PF01926 50S ribosome-binding GTPase 159 280 5.8E-23 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c03080 8200f649750c501be541a75620fa084f 417 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 181 199 4.7E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c03080 8200f649750c501be541a75620fa084f 417 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 160 180 4.7E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c03080 8200f649750c501be541a75620fa084f 417 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 4.7E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c03080 8200f649750c501be541a75620fa084f 417 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 4.7E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c03080 8200f649750c501be541a75620fa084f 417 PIRSF PIRSF002401 1 342 3.2E-131 T 12-10-2018 IPR035101 GTP-binding protein, Obg-type TSC_c03080 8200f649750c501be541a75620fa084f 417 Gene3D G3DSA:3.40.50.300 155 330 2.7E-55 T 12-10-2018 TSC_c03080 8200f649750c501be541a75620fa084f 417 SUPERFAMILY SSF52540 148 331 2.73E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c03080 8200f649750c501be541a75620fa084f 417 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 347 414 4.1E-18 T 12-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 TSC_c03080 8200f649750c501be541a75620fa084f 417 SUPERFAMILY SSF82051 1 155 2.75E-52 T 12-10-2018 IPR036726 GTP1/OBG domain superfamily TSC_c03510 63987f40798ac8f19de89f832b8d1a18 538 Gene3D G3DSA:3.30.70.270 372 538 3.7E-51 T 12-10-2018 TSC_c03510 63987f40798ac8f19de89f832b8d1a18 538 SUPERFAMILY SSF55073 382 537 2.43E-43 T 12-10-2018 IPR029787 Nucleotide cyclase TSC_c03510 63987f40798ac8f19de89f832b8d1a18 538 SMART SM00267 364 538 2.0E-54 T 12-10-2018 IPR000160 GGDEF domain TSC_c03510 63987f40798ac8f19de89f832b8d1a18 538 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 376 537 1.7E-44 T 12-10-2018 IPR000160 GGDEF domain TSC_c03510 63987f40798ac8f19de89f832b8d1a18 538 Pfam PF00990 Diguanylate cyclase, GGDEF domain 377 534 8.8E-41 T 12-10-2018 IPR000160 GGDEF domain TSC_c09410 f3e191dea0abbaa6a6d0dc2472bfd59e 95 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 90 17.55 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 TSC_c09410 f3e191dea0abbaa6a6d0dc2472bfd59e 95 SUPERFAMILY SSF89919 7 89 8.37E-19 T 12-10-2018 IPR023799 Ribosome-binding factor A domain superfamily TSC_c09410 f3e191dea0abbaa6a6d0dc2472bfd59e 95 Pfam PF02033 Ribosome-binding factor A 7 88 4.7E-15 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 TSC_c09410 f3e191dea0abbaa6a6d0dc2472bfd59e 95 Gene3D G3DSA:3.30.300.20 1 95 1.1E-21 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TSC_c09410 f3e191dea0abbaa6a6d0dc2472bfd59e 95 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 8 87 2.0E-9 T 12-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 TSC_c20900 7a9d5a84ce5122fc8ad4b333275137f0 184 SUPERFAMILY SSF50022 60 175 3.67E-20 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSC_c20900 7a9d5a84ce5122fc8ad4b333275137f0 184 Gene3D G3DSA:2.102.10.10 44 178 8.3E-25 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSC_c20900 7a9d5a84ce5122fc8ad4b333275137f0 184 Pfam PF00355 Rieske [2Fe-2S] domain 92 158 6.1E-8 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TSC_c09320 db26cfc380f0a3fa4d3a2120aa7ccb60 138 SUPERFAMILY SSF55486 7 137 1.12E-34 T 12-10-2018 TSC_c09320 db26cfc380f0a3fa4d3a2120aa7ccb60 138 Pfam PF02130 Uncharacterized protein family UPF0054 19 137 7.3E-31 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TSC_c09320 db26cfc380f0a3fa4d3a2120aa7ccb60 138 Gene3D G3DSA:3.40.390.30 2 138 9.2E-36 T 12-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 TSC_c09320 db26cfc380f0a3fa4d3a2120aa7ccb60 138 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 138 16.837 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TSC_c09320 db26cfc380f0a3fa4d3a2120aa7ccb60 138 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 34 137 1.9E-27 T 12-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 TSC_c16300 1df3605a652c1fe52aa3139e1eaa0bf3 800 SUPERFAMILY SSF52540 113 537 2.89E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c16300 1df3605a652c1fe52aa3139e1eaa0bf3 800 Pfam PF02534 Type IV secretory system Conjugative DNA transfer 289 533 8.0E-26 T 12-10-2018 IPR003688 Type IV secretion system protein TraG/VirD4 GO:0009291|GO:0016020 TSC_c16300 1df3605a652c1fe52aa3139e1eaa0bf3 800 Gene3D G3DSA:3.40.50.300 326 540 8.3E-24 T 12-10-2018 TSC_c13390 2672ef518c75f54739a78d57d4b2eb4f 530 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 260 267 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TSC_c13390 2672ef518c75f54739a78d57d4b2eb4f 530 Gene3D G3DSA:3.40.309.10 267 469 9.0E-142 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSC_c13390 2672ef518c75f54739a78d57d4b2eb4f 530 Pfam PF00171 Aldehyde dehydrogenase family 29 498 8.9E-136 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSC_c13390 2672ef518c75f54739a78d57d4b2eb4f 530 Gene3D G3DSA:3.40.605.10 25 493 9.0E-142 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSC_c13390 2672ef518c75f54739a78d57d4b2eb4f 530 SUPERFAMILY SSF53720 11 501 2.23E-138 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 Gene3D G3DSA:3.30.499.20 3 372 3.1E-160 T 12-10-2018 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 SUPERFAMILY SSF52016 637 894 1.49E-84 T 12-10-2018 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 Gene3D G3DSA:3.20.19.10 658 896 1.3E-104 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 ProSitePatterns PS00450 Aconitase family signature 1. 433 449 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 Pfam PF00330 Aconitase family (aconitate hydratase) 77 568 3.4E-180 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 Gene3D G3DSA:3.30.499.10 373 596 5.1E-107 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 SUPERFAMILY SSF53732 3 632 4.45E-229 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 PRINTS PR00415 Aconitase family signature 168 176 2.6E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 PRINTS PR00415 Aconitase family signature 144 157 2.6E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 PRINTS PR00415 Aconitase family signature 201 214 2.6E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 PRINTS PR00415 Aconitase family signature 437 448 2.6E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 PRINTS PR00415 Aconitase family signature 372 386 2.6E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 PRINTS PR00415 Aconitase family signature 277 290 2.6E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 PRINTS PR00415 Aconitase family signature 291 304 2.6E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 PRINTS PR00415 Aconitase family signature 215 230 2.6E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 PRINTS PR00415 Aconitase family signature 499 512 2.6E-42 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 17 895 0.0 T 12-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 Pfam PF00694 Aconitase C-terminal domain 696 822 3.1E-45 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 TSC_c08810 0f75f87056ea32ac57aa6cc1b30791ed 901 Gene3D G3DSA:1.10.1440.20 597 657 7.6E-22 T 12-10-2018 TSC_c04140 ae5af8e27a0b0f8503edd7399cbebd00 197 Gene3D G3DSA:3.90.1140.10 1 197 2.4E-60 T 12-10-2018 TSC_c04140 ae5af8e27a0b0f8503edd7399cbebd00 197 Pfam PF13563 2'-5' RNA ligase superfamily 21 162 4.2E-14 T 12-10-2018 TSC_c04140 ae5af8e27a0b0f8503edd7399cbebd00 197 SUPERFAMILY SSF55144 1 180 5.23E-45 T 12-10-2018 IPR009097 Cyclic phosphodiesterase TSC_c04140 ae5af8e27a0b0f8503edd7399cbebd00 197 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 178 24.126 T 12-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 TSC_c04140 ae5af8e27a0b0f8503edd7399cbebd00 197 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 178 6.5E-33 T 12-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 TSC_c21180 fbcad0b09ea80ca011eacf38084c7c8c 549 TIGRFAM TIGR00337 PyrG: CTP synthase 13 542 6.1E-231 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TSC_c21180 fbcad0b09ea80ca011eacf38084c7c8c 549 SUPERFAMILY SSF52317 300 546 5.35E-78 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c21180 fbcad0b09ea80ca011eacf38084c7c8c 549 Gene3D G3DSA:3.40.50.300 1 296 2.9E-135 T 12-10-2018 TSC_c21180 fbcad0b09ea80ca011eacf38084c7c8c 549 Hamap MF_01227 CTP synthase [pyrG]. 12 547 51.619 T 12-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TSC_c21180 fbcad0b09ea80ca011eacf38084c7c8c 549 Pfam PF06418 CTP synthase N-terminus 13 277 3.7E-123 T 12-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 TSC_c21180 fbcad0b09ea80ca011eacf38084c7c8c 549 Pfam PF00117 Glutamine amidotransferase class-I 312 542 1.0E-47 T 12-10-2018 IPR017926 Glutamine amidotransferase TSC_c21180 fbcad0b09ea80ca011eacf38084c7c8c 549 SUPERFAMILY SSF52540 13 279 1.04E-117 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c21180 fbcad0b09ea80ca011eacf38084c7c8c 549 Gene3D G3DSA:3.40.50.880 297 548 1.8E-104 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c20040 b5a18ab20add2bb13e396fd003ae7724 404 SUPERFAMILY SSF63867 328 401 1.57E-15 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSC_c20040 b5a18ab20add2bb13e396fd003ae7724 404 Pfam PF03453 MoeA N-terminal region (domain I and II) 5 169 2.1E-40 T 12-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSC_c20040 b5a18ab20add2bb13e396fd003ae7724 404 SMART SM00852 182 318 1.1E-38 T 12-10-2018 IPR001453 MoaB/Mog domain TSC_c20040 b5a18ab20add2bb13e396fd003ae7724 404 SUPERFAMILY SSF53218 179 323 1.27E-38 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSC_c20040 b5a18ab20add2bb13e396fd003ae7724 404 Gene3D G3DSA:3.90.105.10 25 176 3.1E-104 T 12-10-2018 TSC_c20040 b5a18ab20add2bb13e396fd003ae7724 404 Gene3D G3DSA:3.40.980.10 177 316 3.1E-104 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSC_c20040 b5a18ab20add2bb13e396fd003ae7724 404 Gene3D G3DSA:2.170.190.11 48 143 3.1E-104 T 12-10-2018 TSC_c20040 b5a18ab20add2bb13e396fd003ae7724 404 Pfam PF00994 Probable molybdopterin binding domain 182 316 3.6E-22 T 12-10-2018 IPR001453 MoaB/Mog domain TSC_c20040 b5a18ab20add2bb13e396fd003ae7724 404 Pfam PF03454 MoeA C-terminal region (domain IV) 332 400 2.1E-16 T 12-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSC_c20040 b5a18ab20add2bb13e396fd003ae7724 404 Gene3D G3DSA:2.40.340.10 329 397 4.1E-16 T 12-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSC_c20040 b5a18ab20add2bb13e396fd003ae7724 404 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 179 308 2.8E-26 T 12-10-2018 IPR001453 MoaB/Mog domain TSC_c20040 b5a18ab20add2bb13e396fd003ae7724 404 SUPERFAMILY SSF63882 5 178 1.44E-51 T 12-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSC_c11030 72775eee1b955ce73cca6df39d64e370 486 SMART SM00534 315 486 6.7E-8 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TSC_c11030 72775eee1b955ce73cca6df39d64e370 486 Pfam PF00488 MutS domain V 318 442 1.5E-16 T 12-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 TSC_c11030 72775eee1b955ce73cca6df39d64e370 486 SUPERFAMILY SSF52540 279 444 9.04E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c11030 72775eee1b955ce73cca6df39d64e370 486 Gene3D G3DSA:3.40.50.300 280 484 2.3E-35 T 12-10-2018 TSC_c02970 42b442c0fc0e2962ed4508f7db11361a 374 Gene3D G3DSA:3.40.50.2000 181 358 4.3E-43 T 12-10-2018 TSC_c02970 42b442c0fc0e2962ed4508f7db11361a 374 Pfam PF13477 Glycosyl transferase 4-like 19 157 6.4E-7 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSC_c02970 42b442c0fc0e2962ed4508f7db11361a 374 Gene3D G3DSA:3.40.50.2000 25 366 4.3E-43 T 12-10-2018 TSC_c02970 42b442c0fc0e2962ed4508f7db11361a 374 SUPERFAMILY SSF53756 23 369 3.18E-61 T 12-10-2018 TSC_c02970 42b442c0fc0e2962ed4508f7db11361a 374 Pfam PF13692 Glycosyl transferases group 1 201 337 2.4E-27 T 12-10-2018 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 4 972 0.0 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 Gene3D G3DSA:3.30.470.20 662 933 8.1E-99 T 12-10-2018 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 835 842 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 669 871 1.6E-31 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 9.5E-68 T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 12-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 SMART SM01096 423 543 3.1E-62 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 Gene3D G3DSA:3.30.470.20 119 406 1.2E-120 T 12-10-2018 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 SUPERFAMILY SSF52440 1 127 6.47E-46 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 Gene3D G3DSA:3.40.50.20 1 116 9.2E-47 T 12-10-2018 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 SUPERFAMILY SSF48108 402 550 2.22E-45 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1021 12.362 T 12-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 429 543 3.2E-36 T 12-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 Gene3D G3DSA:1.10.1030.10 407 549 1.3E-39 T 12-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 SUPERFAMILY SSF56059 128 407 1.75E-103 T 12-10-2018 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 1.1E-65 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 1.1E-65 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 1.1E-65 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 1.1E-65 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 386 404 1.1E-65 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 1.1E-65 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 1.1E-65 T 12-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 SUPERFAMILY SSF52440 553 671 1.25E-48 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 SUPERFAMILY SSF56059 669 931 9.55E-89 T 12-10-2018 TSC_c14100 410f91b4c75b17cf5ab3b1d176f238bf 1035 Gene3D G3DSA:3.40.50.20 551 658 6.5E-47 T 12-10-2018 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 8 1499 18.002 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Gene3D G3DSA:1.10.150.390 1438 1501 1.4E-30 T 12-10-2018 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Gene3D G3DSA:2.40.50.100 254 315 1.1E-17 T 12-10-2018 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Pfam PF04997 RNA polymerase Rpb1, domain 1 9 167 3.0E-34 T 12-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Pfam PF04998 RNA polymerase Rpb1, domain 5 1301 1436 2.0E-13 T 12-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Gene3D G3DSA:2.40.50.410 405 462 1.4E-37 T 12-10-2018 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Gene3D G3DSA:1.10.40.90 657 702 1.4E-23 T 12-10-2018 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Gene3D G3DSA:1.20.120.1280 7 129 5.4E-5 T 12-10-2018 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Gene3D G3DSA:1.10.1790.20 1260 1436 1.9E-71 T 12-10-2018 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Gene3D G3DSA:2.40.50.100 1276 1337 1.9E-71 T 12-10-2018 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 458 1485 0.0 T 12-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Pfam PF04998 RNA polymerase Rpb1, domain 5 1071 1295 4.5E-42 T 12-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Pfam PF04997 RNA polymerase Rpb1, domain 1 481 625 4.8E-46 T 12-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 SUPERFAMILY SSF64484 10 1490 0.0 T 12-10-2018 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Gene3D G3DSA:1.10.132.30 958 1095 7.8E-62 T 12-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Pfam PF04983 RNA polymerase Rpb1, domain 3 775 960 1.1E-28 T 12-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Pfam PF00623 RNA polymerase Rpb1, domain 2 627 768 1.2E-35 T 12-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 SMART SM00663 517 800 2.6E-164 T 12-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Gene3D G3DSA:3.90.105.30 1122 1196 1.7E-42 T 12-10-2018 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Gene3D G3DSA:1.10.274.100 776 957 8.1E-62 T 12-10-2018 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Gene3D G3DSA:2.40.50.410 155 218 6.7E-34 T 12-10-2018 TSC_c04240 b475306c6caca89dfc1df16d199992ce 1530 Pfam PF05000 RNA polymerase Rpb1, domain 4 991 1057 6.5E-15 T 12-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c12910 505dadbedd4001f7d2fb7f906233a05c 459 Pfam PF13556 PucR C-terminal helix-turn-helix domain 394 451 1.9E-18 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain TSC_c12910 505dadbedd4001f7d2fb7f906233a05c 459 SUPERFAMILY SSF88659 375 433 6.98E-7 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSC_c12910 505dadbedd4001f7d2fb7f906233a05c 459 Gene3D G3DSA:1.10.10.2840 340 457 1.1E-21 T 12-10-2018 TSC_c12910 505dadbedd4001f7d2fb7f906233a05c 459 Pfam PF07905 Purine catabolism regulatory protein-like family 7 124 1.2E-24 T 12-10-2018 IPR012914 Purine catabolism PurC-like domain TSC_c10600 564d4d96c79fa1b0b1fbd5592fc979c7 250 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 245 43.798 T 12-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TSC_c10600 564d4d96c79fa1b0b1fbd5592fc979c7 250 Gene3D G3DSA:3.20.20.370 1 250 4.9E-104 T 12-10-2018 TSC_c10600 564d4d96c79fa1b0b1fbd5592fc979c7 250 SUPERFAMILY SSF88713 1 250 2.0E-94 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSC_c10600 564d4d96c79fa1b0b1fbd5592fc979c7 250 Pfam PF03746 LamB/YcsF family 3 241 4.8E-96 T 12-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 TSC_c19510 dcdab92fe40d2ccde56747ae5e56530f 58 Gene3D G3DSA:3.40.50.150 13 58 1.3E-11 T 12-10-2018 TSC_c19510 dcdab92fe40d2ccde56747ae5e56530f 58 SUPERFAMILY SSF53335 6 57 1.56E-7 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c22390 640b2df5bccce5110a274e7c02adc24c 113 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 12-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22390 640b2df5bccce5110a274e7c02adc24c 113 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 29.978 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22390 640b2df5bccce5110a274e7c02adc24c 113 Gene3D G3DSA:3.90.470.10 1 113 1.4E-48 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TSC_c22390 640b2df5bccce5110a274e7c02adc24c 113 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 2.4E-36 T 12-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 TSC_c22390 640b2df5bccce5110a274e7c02adc24c 113 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 106 2.9E-41 T 12-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22390 640b2df5bccce5110a274e7c02adc24c 113 SUPERFAMILY SSF54843 1 110 3.01E-44 T 12-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 TSC_c19740 52ddc5f8654892ebf97903216c19d1e2 335 Gene3D G3DSA:3.50.50.60 5 308 1.8E-121 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c19740 52ddc5f8654892ebf97903216c19d1e2 335 Hamap MF_01685 Ferredoxin--NADP reductase. 3 328 43.491 T 12-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 TSC_c19740 52ddc5f8654892ebf97903216c19d1e2 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.4E-21 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c19740 52ddc5f8654892ebf97903216c19d1e2 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 148 172 1.4E-21 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c19740 52ddc5f8654892ebf97903216c19d1e2 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 219 1.4E-21 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c19740 52ddc5f8654892ebf97903216c19d1e2 335 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 109 117 1.4E-21 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c19740 52ddc5f8654892ebf97903216c19d1e2 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 3.4E-23 T 12-10-2018 TSC_c19740 52ddc5f8654892ebf97903216c19d1e2 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 287 3.4E-23 T 12-10-2018 TSC_c19740 52ddc5f8654892ebf97903216c19d1e2 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 3.4E-23 T 12-10-2018 TSC_c19740 52ddc5f8654892ebf97903216c19d1e2 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.4E-23 T 12-10-2018 TSC_c19740 52ddc5f8654892ebf97903216c19d1e2 335 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 3.4E-23 T 12-10-2018 TSC_c19740 52ddc5f8654892ebf97903216c19d1e2 335 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 287 4.5E-38 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSC_c19740 52ddc5f8654892ebf97903216c19d1e2 335 SUPERFAMILY SSF51905 1 313 1.5E-48 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c19740 52ddc5f8654892ebf97903216c19d1e2 335 Gene3D G3DSA:3.50.50.60 125 247 1.8E-121 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c22430 c95cb74308fd910d6cce363bb0c80cd7 205 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 21 198 2.1E-63 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22430 c95cb74308fd910d6cce363bb0c80cd7 205 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 202 27.864 T 12-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22430 c95cb74308fd910d6cce363bb0c80cd7 205 Pfam PF00573 Ribosomal protein L4/L1 family 21 199 4.4E-56 T 12-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 TSC_c22430 c95cb74308fd910d6cce363bb0c80cd7 205 SUPERFAMILY SSF52166 15 201 1.57E-62 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TSC_c22430 c95cb74308fd910d6cce363bb0c80cd7 205 Gene3D G3DSA:3.40.1370.10 1 205 1.4E-71 T 12-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 TSC_c05390 a542ffb25ebc045b71da74bc7138bfec 128 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 128 11.556 T 12-10-2018 IPR022907 VapC family GO:0004540 TSC_c05390 a542ffb25ebc045b71da74bc7138bfec 128 Gene3D G3DSA:3.40.50.1010 1 127 3.2E-38 T 12-10-2018 TSC_c05390 a542ffb25ebc045b71da74bc7138bfec 128 Pfam PF01850 PIN domain 1 124 3.9E-14 T 12-10-2018 IPR002716 PIN domain TSC_c05390 a542ffb25ebc045b71da74bc7138bfec 128 SUPERFAMILY SSF88723 1 125 8.18E-19 T 12-10-2018 IPR029060 PIN-like domain superfamily TSC_c11200 70a0609ce4febd5e69a18c4b393bf698 307 Gene3D G3DSA:1.10.760.10 187 284 5.0E-32 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c11200 70a0609ce4febd5e69a18c4b393bf698 307 SUPERFAMILY SSF46626 67 173 5.34E-22 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c11200 70a0609ce4febd5e69a18c4b393bf698 307 SUPERFAMILY SSF46626 189 274 3.15E-21 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c11200 70a0609ce4febd5e69a18c4b393bf698 307 Gene3D G3DSA:1.10.760.10 53 176 4.8E-33 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c11200 70a0609ce4febd5e69a18c4b393bf698 307 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 194 268 4.3E-12 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c11200 70a0609ce4febd5e69a18c4b393bf698 307 PRINTS PR00605 Class IC cytochrome C signature 205 216 2.6E-5 T 12-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 TSC_c11200 70a0609ce4febd5e69a18c4b393bf698 307 PRINTS PR00605 Class IC cytochrome C signature 246 268 2.6E-5 T 12-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 TSC_c00040 26493cba03d9d687ca5d41a7399a7847 474 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 12-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSC_c00040 26493cba03d9d687ca5d41a7399a7847 474 Pfam PF02887 Pyruvate kinase, alpha/beta domain 358 470 1.3E-35 T 12-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSC_c00040 26493cba03d9d687ca5d41a7399a7847 474 SUPERFAMILY SSF50800 73 168 1.62E-28 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TSC_c00040 26493cba03d9d687ca5d41a7399a7847 474 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 5 473 3.3E-173 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSC_c00040 26493cba03d9d687ca5d41a7399a7847 474 PRINTS PR01050 Pyruvate kinase family signature 217 243 6.3E-67 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSC_c00040 26493cba03d9d687ca5d41a7399a7847 474 PRINTS PR01050 Pyruvate kinase family signature 244 268 6.3E-67 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSC_c00040 26493cba03d9d687ca5d41a7399a7847 474 PRINTS PR01050 Pyruvate kinase family signature 269 293 6.3E-67 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSC_c00040 26493cba03d9d687ca5d41a7399a7847 474 PRINTS PR01050 Pyruvate kinase family signature 187 201 6.3E-67 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSC_c00040 26493cba03d9d687ca5d41a7399a7847 474 PRINTS PR01050 Pyruvate kinase family signature 62 78 6.3E-67 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSC_c00040 26493cba03d9d687ca5d41a7399a7847 474 PRINTS PR01050 Pyruvate kinase family signature 294 312 6.3E-67 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSC_c00040 26493cba03d9d687ca5d41a7399a7847 474 PRINTS PR01050 Pyruvate kinase family signature 313 329 6.3E-67 T 12-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSC_c00040 26493cba03d9d687ca5d41a7399a7847 474 Gene3D G3DSA:2.40.33.10 73 169 1.0E-186 T 12-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSC_c00040 26493cba03d9d687ca5d41a7399a7847 474 Gene3D G3DSA:3.40.1380.20 336 469 1.0E-186 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSC_c00040 26493cba03d9d687ca5d41a7399a7847 474 SUPERFAMILY SSF51621 3 338 5.71E-102 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSC_c00040 26493cba03d9d687ca5d41a7399a7847 474 SUPERFAMILY SSF52935 323 473 9.29E-43 T 12-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSC_c00040 26493cba03d9d687ca5d41a7399a7847 474 Gene3D G3DSA:3.20.20.60 5 335 1.0E-186 T 12-10-2018 TSC_c00040 26493cba03d9d687ca5d41a7399a7847 474 Pfam PF00224 Pyruvate kinase, barrel domain 5 337 1.9E-129 T 12-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 TSC_c20740 87480bd5addc5970b90afaa5cd24e4fd 123 SUPERFAMILY SSF88723 15 120 6.45E-12 T 12-10-2018 IPR029060 PIN-like domain superfamily TSC_c08670 9cd97ef907aa3f0defacf509d8b9c70a 275 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 15 41 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TSC_c08670 9cd97ef907aa3f0defacf509d8b9c70a 275 PIRSF PIRSF000654 6 254 2.4E-20 T 12-10-2018 TSC_c08670 9cd97ef907aa3f0defacf509d8b9c70a 275 Gene3D G3DSA:1.10.510.10 84 268 2.1E-42 T 12-10-2018 TSC_c08670 9cd97ef907aa3f0defacf509d8b9c70a 275 SMART SM00220 9 252 3.7E-42 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TSC_c08670 9cd97ef907aa3f0defacf509d8b9c70a 275 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 126 138 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TSC_c08670 9cd97ef907aa3f0defacf509d8b9c70a 275 SUPERFAMILY SSF56112 5 252 2.23E-61 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TSC_c08670 9cd97ef907aa3f0defacf509d8b9c70a 275 Pfam PF00069 Protein kinase domain 12 249 9.6E-41 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TSC_c08670 9cd97ef907aa3f0defacf509d8b9c70a 275 Gene3D G3DSA:3.30.200.20 2 83 2.5E-13 T 12-10-2018 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 Gene3D G3DSA:1.10.460.10 129 570 2.9E-164 T 12-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 Gene3D G3DSA:3.30.65.10 624 667 5.3E-9 T 12-10-2018 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 Gene3D G3DSA:3.30.65.10 575 623 8.5E-6 T 12-10-2018 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 1 618 1.2E-222 T 12-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 Pfam PF01751 Toprim domain 1 107 4.2E-23 T 12-10-2018 IPR006171 TOPRIM domain TSC_c23030 53bbcd77d4a402283640187043c9206e 849 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 629 662 1.1E-14 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 584 620 4.3E-13 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 708 720 2.4 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 669 701 1.2E-4 T 12-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 SMART SM00437 249 530 5.4E-115 T 12-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 Pfam PF01131 DNA topoisomerase 122 567 4.2E-127 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 Gene3D G3DSA:2.70.20.10 179 477 2.9E-164 T 12-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 SUPERFAMILY SSF57783 579 621 1.24E-10 T 12-10-2018 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 SMART SM00493 1 97 3.2E-26 T 12-10-2018 IPR006171 TOPRIM domain TSC_c23030 53bbcd77d4a402283640187043c9206e 849 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 377 393 5.3E-37 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 493 507 5.3E-37 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 299 308 5.3E-37 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 71 84 5.3E-37 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 157 175 5.3E-37 T 12-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 Gene3D G3DSA:3.40.50.140 1 128 7.7E-48 T 12-10-2018 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 Gene3D G3DSA:1.10.290.10 257 392 2.9E-164 T 12-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 286 308 - T 12-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 SUPERFAMILY SSF57783 628 662 2.55E-11 T 12-10-2018 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 Hamap MF_00952 DNA topoisomerase 1 [topA]. 1 693 52.582 T 12-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 TSC_c23030 53bbcd77d4a402283640187043c9206e 849 SUPERFAMILY SSF56712 1 581 9.55E-187 T 12-10-2018 IPR023405 DNA topoisomerase, type IA, core domain TSC_c23030 53bbcd77d4a402283640187043c9206e 849 SMART SM00436 98 187 2.9E-49 T 12-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 TSC_c19370 2c72c4b0729fa9b0682dce8bc018f83a 126 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 117 3.8E-10 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TSC_c19370 2c72c4b0729fa9b0682dce8bc018f83a 126 Gene3D G3DSA:3.10.180.10 4 126 1.7E-29 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c19370 2c72c4b0729fa9b0682dce8bc018f83a 126 SUPERFAMILY SSF54593 7 118 7.12E-28 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c14280 933fe1725b3623f94d1a58d392f24b69 126 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 124 22.255 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TSC_c14280 933fe1725b3623f94d1a58d392f24b69 126 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 120 5.6E-33 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TSC_c14280 933fe1725b3623f94d1a58d392f24b69 126 SUPERFAMILY SSF81330 10 118 6.41E-29 T 12-10-2018 IPR036019 Gated mechanosensitive channel TSC_c14280 933fe1725b3623f94d1a58d392f24b69 126 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 122 3.4E-37 T 12-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L TSC_c14280 933fe1725b3623f94d1a58d392f24b69 126 Gene3D G3DSA:1.10.1200.120 1 126 4.3E-36 T 12-10-2018 IPR036019 Gated mechanosensitive channel TSC_c14280 933fe1725b3623f94d1a58d392f24b69 126 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 5.2E-7 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TSC_c14280 933fe1725b3623f94d1a58d392f24b69 126 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 71 79 5.2E-7 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TSC_c14280 933fe1725b3623f94d1a58d392f24b69 126 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 81 90 5.2E-7 T 12-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 TSC_c14280 933fe1725b3623f94d1a58d392f24b69 126 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 12-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site TSC_c05490 07ac582d89669c2412e78dc405fa0bc2 216 SUPERFAMILY SSF46785 142 212 7.08E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c05490 07ac582d89669c2412e78dc405fa0bc2 216 SMART SM00100 6 127 3.6E-23 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain TSC_c05490 07ac582d89669c2412e78dc405fa0bc2 216 ProSitePatterns PS00889 Cyclic nucleotide-binding domain signature 2. 74 91 - T 12-10-2018 IPR018488 Cyclic nucleotide-binding, conserved site TSC_c05490 07ac582d89669c2412e78dc405fa0bc2 216 Pfam PF13545 Crp-like helix-turn-helix domain 145 210 1.2E-14 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSC_c05490 07ac582d89669c2412e78dc405fa0bc2 216 Pfam PF00027 Cyclic nucleotide-binding domain 25 110 6.2E-24 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain TSC_c05490 07ac582d89669c2412e78dc405fa0bc2 216 Gene3D G3DSA:1.10.10.10 140 216 2.7E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c05490 07ac582d89669c2412e78dc405fa0bc2 216 Gene3D G3DSA:2.60.120.10 2 139 6.0E-46 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TSC_c05490 07ac582d89669c2412e78dc405fa0bc2 216 PRINTS PR00103 cAMP-dependent protein kinase signature 42 56 2.9E-5 T 12-10-2018 TSC_c05490 07ac582d89669c2412e78dc405fa0bc2 216 PRINTS PR00103 cAMP-dependent protein kinase signature 72 81 2.9E-5 T 12-10-2018 TSC_c05490 07ac582d89669c2412e78dc405fa0bc2 216 PRINTS PR00103 cAMP-dependent protein kinase signature 84 95 2.9E-5 T 12-10-2018 TSC_c05490 07ac582d89669c2412e78dc405fa0bc2 216 PRINTS PR00103 cAMP-dependent protein kinase signature 27 41 2.9E-5 T 12-10-2018 TSC_c05490 07ac582d89669c2412e78dc405fa0bc2 216 SUPERFAMILY SSF51206 4 137 6.55E-37 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like TSC_c05490 07ac582d89669c2412e78dc405fa0bc2 216 SMART SM00419 158 204 9.3E-7 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSC_c00280 aff62dfe9e619217b96d620bc0daac39 189 Gene3D G3DSA:1.10.357.10 1 174 8.9E-31 T 12-10-2018 TSC_c00280 aff62dfe9e619217b96d620bc0daac39 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 1 14 1.4E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSC_c00280 aff62dfe9e619217b96d620bc0daac39 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 45 1.4E-10 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSC_c00280 aff62dfe9e619217b96d620bc0daac39 189 SUPERFAMILY SSF48498 67 174 1.03E-10 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSC_c00280 aff62dfe9e619217b96d620bc0daac39 189 SUPERFAMILY SSF46689 1 52 3.69E-14 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSC_c00280 aff62dfe9e619217b96d620bc0daac39 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 1 47 1.3E-17 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSC_c13160 f3ec2d4be7ca3a469ce91438e9413923 340 Hamap MF_00117 33 kDa chaperonin [hslO]. 1 298 34.545 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 TSC_c13160 f3ec2d4be7ca3a469ce91438e9413923 340 Pfam PF01430 Hsp33 protein 4 287 6.4E-79 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 TSC_c13160 f3ec2d4be7ca3a469ce91438e9413923 340 SUPERFAMILY SSF64397 4 249 1.11E-62 T 12-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 TSC_c13160 f3ec2d4be7ca3a469ce91438e9413923 340 PIRSF PIRSF005261 1 299 2.5E-68 T 12-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 TSC_c13160 f3ec2d4be7ca3a469ce91438e9413923 340 SUPERFAMILY SSF118352 239 297 1.07E-18 T 12-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 TSC_c13160 f3ec2d4be7ca3a469ce91438e9413923 340 Gene3D G3DSA:3.90.1280.10 244 311 2.5E-16 T 12-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 TSC_c13160 f3ec2d4be7ca3a469ce91438e9413923 340 Gene3D G3DSA:3.55.30.10 1 229 2.0E-79 T 12-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 TSC_c10700 3ecb064233a0ef02bb505a1b6b7f7c60 311 Gene3D G3DSA:1.10.3720.10 86 303 3.9E-19 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c10700 3ecb064233a0ef02bb505a1b6b7f7c60 311 SUPERFAMILY SSF161098 91 296 2.83E-17 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c10700 3ecb064233a0ef02bb505a1b6b7f7c60 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 309 1.7E-34 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c07240 c23259893f3a021a92b89599d9b2683a 270 Hamap MF_00995 Chorismate dehydratase [mqnA]. 4 265 28.574 T 12-10-2018 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 TSC_c07240 c23259893f3a021a92b89599d9b2683a 270 Gene3D G3DSA:3.40.190.10 9 255 3.0E-70 T 12-10-2018 TSC_c07240 c23259893f3a021a92b89599d9b2683a 270 Gene3D G3DSA:3.40.190.10 72 194 3.0E-70 T 12-10-2018 TSC_c07240 c23259893f3a021a92b89599d9b2683a 270 Pfam PF02621 Menaquinone biosynthesis 4 258 3.1E-62 T 12-10-2018 IPR003773 Menaquinone biosynthesis enzyme TSC_c07240 c23259893f3a021a92b89599d9b2683a 270 SUPERFAMILY SSF53850 5 258 5.7E-70 T 12-10-2018 TSC_c01540 5088de36bbc23b4e706634daff151d41 362 SUPERFAMILY SSF52540 9 338 3.47E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c01540 5088de36bbc23b4e706634daff151d41 362 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 197 211 - T 12-10-2018 IPR001482 Type II/IV secretion system protein TSC_c01540 5088de36bbc23b4e706634daff151d41 362 SMART SM00382 126 251 0.0016 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c01540 5088de36bbc23b4e706634daff151d41 362 Gene3D G3DSA:3.40.50.300 105 360 8.1E-101 T 12-10-2018 TSC_c01540 5088de36bbc23b4e706634daff151d41 362 Pfam PF00437 Type II/IV secretion system protein 15 272 1.3E-43 T 12-10-2018 IPR001482 Type II/IV secretion system protein TSC_c01540 5088de36bbc23b4e706634daff151d41 362 Gene3D G3DSA:3.30.450.90 1 104 9.7E-34 T 12-10-2018 TSC_c01540 5088de36bbc23b4e706634daff151d41 362 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 7 348 7.9E-153 T 12-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 TSC_c05550 521f6e1375eef4ecbb80763a40d2d882 548 Pfam PF13193 AMP-binding enzyme C-terminal domain 457 534 1.2E-23 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSC_c05550 521f6e1375eef4ecbb80763a40d2d882 548 Gene3D G3DSA:3.30.300.310 445 547 1.8E-35 T 12-10-2018 TSC_c05550 521f6e1375eef4ecbb80763a40d2d882 548 SUPERFAMILY SSF56801 13 546 2.62E-168 T 12-10-2018 TSC_c05550 521f6e1375eef4ecbb80763a40d2d882 548 ProSitePatterns PS00455 Putative AMP-binding domain signature. 201 212 - T 12-10-2018 IPR020845 AMP-binding, conserved site TSC_c05550 521f6e1375eef4ecbb80763a40d2d882 548 Gene3D G3DSA:3.40.50.12780 12 444 5.1E-132 T 12-10-2018 TSC_c05550 521f6e1375eef4ecbb80763a40d2d882 548 Pfam PF00501 AMP-binding enzyme 27 447 2.8E-119 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSC_c03400 e99d54263231312fabd2766224ed2414 166 Pfam PF09988 Uncharacterized metal-binding protein (DUF2227) 2 158 3.4E-39 T 12-10-2018 IPR019250 Protein of unknown function DUF2227, metal-binding TSC_c06130 27e804be03d51c9d12a93c04433eae1b 234 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 59 218 9.4E-52 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 TSC_c06130 27e804be03d51c9d12a93c04433eae1b 234 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 56 224 1.7E-36 T 12-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 TSC_c09180 e05944b2085584801cb2f6d22de5cca9 141 SUPERFAMILY SSF75420 3 74 2.09E-11 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily TSC_c09180 e05944b2085584801cb2f6d22de5cca9 141 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 1 133 13.637 T 12-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 TSC_c09180 e05944b2085584801cb2f6d22de5cca9 141 Gene3D G3DSA:3.30.300.70 2 73 3.8E-7 T 12-10-2018 IPR035956 RimP, N-terminal domain superfamily TSC_c09180 e05944b2085584801cb2f6d22de5cca9 141 Pfam PF02576 RimP N-terminal domain 6 74 1.3E-12 T 12-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal TSC_c09180 e05944b2085584801cb2f6d22de5cca9 141 Pfam PF17384 RimP C-terminal SH3 domain 79 123 1.1E-8 T 12-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal TSC_c09180 e05944b2085584801cb2f6d22de5cca9 141 SUPERFAMILY SSF74942 77 123 7.45E-6 T 12-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily TSC_c20320 473974f01eb32a30a580af17747d33de 129 Pfam PF02915 Rubrerythrin 5 62 1.2E-5 T 12-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 TSC_c20320 473974f01eb32a30a580af17747d33de 129 Gene3D G3DSA:1.20.1260.10 1 125 8.3E-6 T 12-10-2018 IPR012347 Ferritin-like TSC_c20320 473974f01eb32a30a580af17747d33de 129 SUPERFAMILY SSF47240 1 125 5.56E-10 T 12-10-2018 IPR009078 Ferritin-like superfamily TSC_c13460 0bd2403e87c841a0d8dc21d0bc82c31a 432 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 5 432 30.795 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 TSC_c13460 0bd2403e87c841a0d8dc21d0bc82c31a 432 Pfam PF12631 MnmE helical domain 127 429 3.2E-40 T 12-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 TSC_c13460 0bd2403e87c841a0d8dc21d0bc82c31a 432 Gene3D G3DSA:3.30.1360.120 1 124 2.7E-44 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TSC_c13460 0bd2403e87c841a0d8dc21d0bc82c31a 432 Gene3D G3DSA:3.40.50.300 218 364 3.0E-79 T 12-10-2018 TSC_c13460 0bd2403e87c841a0d8dc21d0bc82c31a 432 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 218 305 6.7E-16 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSC_c13460 0bd2403e87c841a0d8dc21d0bc82c31a 432 SUPERFAMILY SSF52540 77 357 2.34E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c13460 0bd2403e87c841a0d8dc21d0bc82c31a 432 Pfam PF10396 GTP-binding protein TrmE N-terminus 6 124 1.7E-38 T 12-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 TSC_c13460 0bd2403e87c841a0d8dc21d0bc82c31a 432 Pfam PF01926 50S ribosome-binding GTPase 220 306 9.7E-19 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c13460 0bd2403e87c841a0d8dc21d0bc82c31a 432 Gene3D G3DSA:1.20.120.430 125 432 3.0E-79 T 12-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 TSC_c13460 0bd2403e87c841a0d8dc21d0bc82c31a 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 287 305 4.2E-6 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c13460 0bd2403e87c841a0d8dc21d0bc82c31a 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 220 240 4.2E-6 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c13460 0bd2403e87c841a0d8dc21d0bc82c31a 432 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 310 1.1E-88 T 12-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 TSC_c08030 84c770797c1131785fead59efebbc9e3 290 SUPERFAMILY SSF48179 185 287 2.55E-35 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSC_c08030 84c770797c1131785fead59efebbc9e3 290 PIRSF PIRSF000105 1 290 3.7E-94 T 12-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 TSC_c08030 84c770797c1131785fead59efebbc9e3 290 SUPERFAMILY SSF51735 1 185 1.09E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c08030 84c770797c1131785fead59efebbc9e3 290 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 282 9.9E-37 T 12-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TSC_c08030 84c770797c1131785fead59efebbc9e3 290 Gene3D G3DSA:3.40.50.720 1 188 5.1E-69 T 12-10-2018 TSC_c08030 84c770797c1131785fead59efebbc9e3 290 Gene3D G3DSA:1.10.1040.10 189 289 2.1E-37 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSC_c08030 84c770797c1131785fead59efebbc9e3 290 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 183 1.7E-65 T 12-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 TSC_c08760 949bd643acabf41030b9b3f2d082186e 323 Hamap MF_00314 V-type ATP synthase subunit C [atpC]. 1 322 22.346 T 12-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 TSC_c08760 949bd643acabf41030b9b3f2d082186e 323 SUPERFAMILY SSF103486 5 321 2.88E-72 T 12-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c08760 949bd643acabf41030b9b3f2d082186e 323 Gene3D G3DSA:1.20.1690.10 78 178 8.2E-96 T 12-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c08760 949bd643acabf41030b9b3f2d082186e 323 Pfam PF01992 ATP synthase (C/AC39) subunit 8 318 2.0E-51 T 12-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c08760 949bd643acabf41030b9b3f2d082186e 323 Gene3D G3DSA:1.10.132.50 5 315 8.2E-96 T 12-10-2018 TSC_c08760 949bd643acabf41030b9b3f2d082186e 323 Gene3D G3DSA:1.20.1690.10 186 281 8.2E-96 T 12-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c21740 3fc8a2a45f1ec58bc2ba7b4cfa8ed048 186 SUPERFAMILY SSF101874 34 185 1.44E-21 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily TSC_c21740 3fc8a2a45f1ec58bc2ba7b4cfa8ed048 186 Gene3D G3DSA:2.40.128.110 25 186 3.4E-24 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily TSC_c21740 3fc8a2a45f1ec58bc2ba7b4cfa8ed048 186 Pfam PF04264 YceI-like domain 36 181 2.7E-18 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TSC_c21740 3fc8a2a45f1ec58bc2ba7b4cfa8ed048 186 SMART SM00867 18 184 1.1E-13 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TSC_c12090 032c64890578f45fefbf4a569e0b684a 127 Pfam PF03061 Thioesterase superfamily 19 92 1.1E-22 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TSC_c12090 032c64890578f45fefbf4a569e0b684a 127 Gene3D G3DSA:3.10.129.10 2 126 1.6E-45 T 12-10-2018 TSC_c12090 032c64890578f45fefbf4a569e0b684a 127 SUPERFAMILY SSF54637 5 125 1.37E-40 T 12-10-2018 IPR029069 HotDog domain superfamily TSC_c18100 b4e173cc5e392d1ba648944d6ad7ee6d 317 Gene3D G3DSA:2.30.140.10 7 57 3.3E-18 T 12-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TSC_c18100 b4e173cc5e392d1ba648944d6ad7ee6d 317 Pfam PF17284 Spermidine synthase tetramerisation domain 10 60 1.4E-9 T 12-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TSC_c18100 b4e173cc5e392d1ba648944d6ad7ee6d 317 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 84 97 - T 12-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TSC_c18100 b4e173cc5e392d1ba648944d6ad7ee6d 317 Gene3D G3DSA:3.40.50.150 59 314 7.4E-92 T 12-10-2018 TSC_c18100 b4e173cc5e392d1ba648944d6ad7ee6d 317 Pfam PF01564 Spermine/spermidine synthase domain 64 234 4.4E-44 T 12-10-2018 TSC_c18100 b4e173cc5e392d1ba648944d6ad7ee6d 317 SUPERFAMILY SSF53335 5 290 1.75E-77 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c18100 b4e173cc5e392d1ba648944d6ad7ee6d 317 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 8 290 34.684 T 12-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 TSC_c13170 28cb92be51c6327e7e61a1452ed325cc 481 Pfam PF09190 DALR domain 362 418 3.3E-8 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TSC_c13170 28cb92be51c6327e7e61a1452ed325cc 481 Gene3D G3DSA:1.20.120.640 317 478 9.5E-32 T 12-10-2018 TSC_c13170 28cb92be51c6327e7e61a1452ed325cc 481 SUPERFAMILY SSF52374 4 323 5.36E-90 T 12-10-2018 TSC_c13170 28cb92be51c6327e7e61a1452ed325cc 481 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 478 36.888 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TSC_c13170 28cb92be51c6327e7e61a1452ed325cc 481 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 477 8.5E-143 T 12-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 TSC_c13170 28cb92be51c6327e7e61a1452ed325cc 481 SUPERFAMILY SSF47323 348 478 2.35E-27 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c13170 28cb92be51c6327e7e61a1452ed325cc 481 SMART SM00840 361 421 8.2E-9 T 12-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 TSC_c13170 28cb92be51c6327e7e61a1452ed325cc 481 Gene3D G3DSA:3.40.50.620 1 315 2.1E-126 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c13170 28cb92be51c6327e7e61a1452ed325cc 481 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 17 323 5.7E-106 T 12-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 TSC_c13170 28cb92be51c6327e7e61a1452ed325cc 481 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 4.0E-25 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TSC_c13170 28cb92be51c6327e7e61a1452ed325cc 481 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 233 254 4.0E-25 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TSC_c13170 28cb92be51c6327e7e61a1452ed325cc 481 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 4.0E-25 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TSC_c13170 28cb92be51c6327e7e61a1452ed325cc 481 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 202 220 4.0E-25 T 12-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 TSC_c03560 e69014ab67210d4714109da470dc96e8 159 SUPERFAMILY SSF55083 2 154 4.84E-56 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TSC_c03560 e69014ab67210d4714109da470dc96e8 159 Gene3D G3DSA:3.30.70.560 2 158 1.3E-56 T 12-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TSC_c03560 e69014ab67210d4714109da470dc96e8 159 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 3 131 1.5E-44 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TSC_c03560 e69014ab67210d4714109da470dc96e8 159 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 86 97 - T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TSC_c03560 e69014ab67210d4714109da470dc96e8 159 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 4 131 2.0E-37 T 12-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 TSC_c23160 8ca6a76c1ac9cad3e1b40d0e60f9b37d 258 Pfam PF01676 Metalloenzyme superfamily 152 228 1.6E-8 T 12-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 TSC_c23160 8ca6a76c1ac9cad3e1b40d0e60f9b37d 258 SUPERFAMILY SSF53649 1 231 1.21E-16 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TSC_c23160 8ca6a76c1ac9cad3e1b40d0e60f9b37d 258 Gene3D G3DSA:3.40.720.10 144 235 7.7E-9 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 Pfam PF14791 DNA polymerase beta thumb 256 315 9.2E-19 T 12-10-2018 IPR029398 DNA polymerase beta, thumb domain TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 SUPERFAMILY SSF47781 94 148 8.58E-9 T 12-10-2018 IPR010994 RuvA domain 2-like TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 Pfam PF14716 Helix-hairpin-helix domain 3 73 1.8E-19 T 12-10-2018 IPR010996 DNA polymerase beta-like, N-terminal domain TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 Gene3D G3DSA:1.10.150.110 1 87 1.9E-23 T 12-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 Gene3D G3DSA:3.30.460.10 157 261 2.2E-27 T 12-10-2018 TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 SMART SM00278 53 72 0.0026 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 SMART SM00278 128 147 0.1 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 SMART SM00278 93 112 0.038 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 SUPERFAMILY SSF47802 1 84 1.74E-18 T 12-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 SUPERFAMILY SSF81301 157 315 2.48E-41 T 12-10-2018 TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 Pfam PF14520 Helix-hairpin-helix domain 95 148 4.8E-14 T 12-10-2018 TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 SMART SM00481 339 418 1.1E-14 T 12-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 PIRSF PIRSF005047 1 573 5.2E-223 T 12-10-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 Pfam PF02811 PHP domain 340 428 3.0E-6 T 12-10-2018 IPR004013 PHP domain GO:0003824 TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 Gene3D G3DSA:3.20.20.140 327 575 2.7E-71 T 12-10-2018 TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 Gene3D G3DSA:1.10.150.20 88 156 2.4E-22 T 12-10-2018 TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 Gene3D G3DSA:3.30.210.10 262 326 3.1E-26 T 12-10-2018 IPR037160 DNA polymerase, thumb domain superfamily TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 SMART SM00483 1 315 1.1E-33 T 12-10-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 297 314 4.1E-9 T 12-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 240 248 4.1E-9 T 12-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 60 77 4.1E-9 T 12-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 PRINTS PR00870 DNA-polymerase family X pol beta-like signature 255 262 4.1E-9 T 12-10-2018 IPR002008 DNA polymerase family X, beta-like GO:0003677|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c13080 ecd3ca492614c2f0260e89917879b7f0 575 SUPERFAMILY SSF89550 338 568 1.44E-47 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TSC_c10240 71d3815a075da4e9c1857af15c96896a 183 Pfam PF00293 NUDIX domain 45 155 2.2E-15 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSC_c10240 71d3815a075da4e9c1857af15c96896a 183 SUPERFAMILY SSF55811 4 175 7.72E-37 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSC_c10240 71d3815a075da4e9c1857af15c96896a 183 PRINTS PR00502 NUDIX hydrolase family signature 70 84 6.1E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSC_c10240 71d3815a075da4e9c1857af15c96896a 183 PRINTS PR00502 NUDIX hydrolase family signature 84 99 6.1E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSC_c10240 71d3815a075da4e9c1857af15c96896a 183 Gene3D G3DSA:3.90.79.10 1 182 9.0E-53 T 12-10-2018 TSC_c10240 71d3815a075da4e9c1857af15c96896a 183 ProSitePatterns PS00893 Nudix box signature. 75 96 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TSC_c22590 d5f4dc19a0b4b4b7857e80de7955ef83 236 Pfam PF01479 S4 domain 6 50 4.5E-15 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22590 d5f4dc19a0b4b4b7857e80de7955ef83 236 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 69 222 3.2E-41 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 TSC_c22590 d5f4dc19a0b4b4b7857e80de7955ef83 236 SUPERFAMILY SSF55174 5 94 1.91E-22 T 12-10-2018 TSC_c22590 d5f4dc19a0b4b4b7857e80de7955ef83 236 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 101 115 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 TSC_c22590 d5f4dc19a0b4b4b7857e80de7955ef83 236 SUPERFAMILY SSF55120 63 228 5.18E-37 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c22590 d5f4dc19a0b4b4b7857e80de7955ef83 236 Pfam PF00849 RNA pseudouridylate synthase 65 143 6.1E-13 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c22590 d5f4dc19a0b4b4b7857e80de7955ef83 236 Gene3D G3DSA:3.10.290.10 1 60 8.9E-26 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TSC_c22590 d5f4dc19a0b4b4b7857e80de7955ef83 236 SMART SM00363 5 65 4.8E-17 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22590 d5f4dc19a0b4b4b7857e80de7955ef83 236 Gene3D G3DSA:3.30.70.580 67 219 3.3E-48 T 12-10-2018 TSC_c22590 d5f4dc19a0b4b4b7857e80de7955ef83 236 Gene3D G3DSA:3.30.70.1560 125 211 3.3E-48 T 12-10-2018 TSC_c17250 cf68dbad10cf91c53d1ecde0760010f2 451 Gene3D G3DSA:3.50.50.60 4 436 1.2E-122 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c17250 cf68dbad10cf91c53d1ecde0760010f2 451 Gene3D G3DSA:3.90.660.20 39 393 1.2E-122 T 12-10-2018 TSC_c17250 cf68dbad10cf91c53d1ecde0760010f2 451 Gene3D G3DSA:1.10.3110.10 96 202 1.2E-122 T 12-10-2018 TSC_c17250 cf68dbad10cf91c53d1ecde0760010f2 451 SUPERFAMILY SSF51905 4 440 5.18E-54 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c17250 cf68dbad10cf91c53d1ecde0760010f2 451 SUPERFAMILY SSF54373 292 392 3.4E-22 T 12-10-2018 TSC_c17250 cf68dbad10cf91c53d1ecde0760010f2 451 Pfam PF01593 Flavin containing amine oxidoreductase 12 441 8.3E-62 T 12-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 TSC_c17250 cf68dbad10cf91c53d1ecde0760010f2 451 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 308 324 7.5E-6 T 12-10-2018 TSC_c17250 cf68dbad10cf91c53d1ecde0760010f2 451 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 7.5E-6 T 12-10-2018 TSC_c17250 cf68dbad10cf91c53d1ecde0760010f2 451 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 2 445 5.1E-79 T 12-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 TSC_c17440 4d8c30df58ce37ea236b5da4872644b2 272 Gene3D G3DSA:1.10.3910.10 4 77 1.5E-11 T 12-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily TSC_c17440 4d8c30df58ce37ea236b5da4872644b2 272 SUPERFAMILY SSF140683 9 79 7.72E-13 T 12-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily TSC_c17440 4d8c30df58ce37ea236b5da4872644b2 272 Pfam PF08984 Domain of unknown function (DUF1858) 14 70 2.6E-12 T 12-10-2018 IPR015077 Domain of unknown function DUF1858 TSC_c17440 4d8c30df58ce37ea236b5da4872644b2 272 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 109 177 8.8E-14 T 12-10-2018 IPR018720 Domain of unknown function DUF2249 TSC_c17440 4d8c30df58ce37ea236b5da4872644b2 272 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 210 270 3.3E-12 T 12-10-2018 IPR018720 Domain of unknown function DUF2249 TSC_c17440 4d8c30df58ce37ea236b5da4872644b2 272 SUPERFAMILY SSF64307 209 271 5.49E-7 T 12-10-2018 IPR036868 TusA-like domain superfamily TSC_c02640 9af52b2924cb696044593909165415e2 191 Pfam PF07499 RuvA, C-terminal domain 145 190 3.0E-10 T 12-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 TSC_c02640 9af52b2924cb696044593909165415e2 191 Pfam PF14520 Helix-hairpin-helix domain 71 128 6.9E-14 T 12-10-2018 TSC_c02640 9af52b2924cb696044593909165415e2 191 SUPERFAMILY SSF47781 67 132 7.23E-18 T 12-10-2018 IPR010994 RuvA domain 2-like TSC_c02640 9af52b2924cb696044593909165415e2 191 Pfam PF01330 RuvA N terminal domain 1 61 1.0E-16 T 12-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 TSC_c02640 9af52b2924cb696044593909165415e2 191 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 190 7.7E-39 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 TSC_c02640 9af52b2924cb696044593909165415e2 191 Gene3D G3DSA:2.40.50.140 1 63 6.8E-24 T 12-10-2018 TSC_c02640 9af52b2924cb696044593909165415e2 191 SUPERFAMILY SSF50249 1 62 1.09E-12 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c02640 9af52b2924cb696044593909165415e2 191 Gene3D G3DSA:1.10.8.10 139 191 1.2E-17 T 12-10-2018 TSC_c02640 9af52b2924cb696044593909165415e2 191 Gene3D G3DSA:1.10.150.20 64 138 4.9E-23 T 12-10-2018 TSC_c02640 9af52b2924cb696044593909165415e2 191 SUPERFAMILY SSF46929 143 190 1.44E-11 T 12-10-2018 IPR036267 RuvA, C-terminal domain superfamily TSC_c02640 9af52b2924cb696044593909165415e2 191 SMART SM00278 72 91 0.065 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSC_c02640 9af52b2924cb696044593909165415e2 191 SMART SM00278 107 126 56.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSC_c02640 9af52b2924cb696044593909165415e2 191 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 191 27.548 T 12-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 TSC_c16200 a5506f4a95d07900ee243b549be2613a 374 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 22 100 1.3E-5 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSC_c16200 a5506f4a95d07900ee243b549be2613a 374 SMART SM00382 17 161 1.2E-4 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c16200 a5506f4a95d07900ee243b549be2613a 374 Gene3D G3DSA:3.40.50.300 4 162 1.4E-15 T 12-10-2018 TSC_c16200 a5506f4a95d07900ee243b549be2613a 374 SUPERFAMILY SSF52540 8 212 1.44E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c00590 8da7462ea47a1723bb03f833a33964c4 224 Pfam PF00005 ABC transporter 13 149 8.6E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c00590 8da7462ea47a1723bb03f833a33964c4 224 ProSitePatterns PS00211 ABC transporters family signature. 121 135 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c00590 8da7462ea47a1723bb03f833a33964c4 224 SUPERFAMILY SSF52540 11 199 1.7E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c00590 8da7462ea47a1723bb03f833a33964c4 224 Gene3D G3DSA:3.40.50.300 3 213 3.2E-52 T 12-10-2018 TSC_c00590 8da7462ea47a1723bb03f833a33964c4 224 SMART SM00382 20 194 1.2E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_p800070 7e9c41f2c36dc1b6bf0f546d9ed0bea9 126 Gene3D G3DSA:1.20.120.330 1 125 1.3E-36 T 12-10-2018 TSC_p800070 7e9c41f2c36dc1b6bf0f546d9ed0bea9 126 Pfam PF05168 HEPN domain 4 122 1.7E-33 T 12-10-2018 IPR007842 HEPN domain TSC_p800070 7e9c41f2c36dc1b6bf0f546d9ed0bea9 126 SMART SM00748 8 117 4.6E-28 T 12-10-2018 IPR007842 HEPN domain TSC_p800070 7e9c41f2c36dc1b6bf0f546d9ed0bea9 126 SUPERFAMILY SSF81593 2 123 3.69E-41 T 12-10-2018 TSC_c18710 ff5245d54e9f169cd396b6da68043d33 437 Pfam PF01134 Glucose inhibited division protein A 4 364 6.5E-106 T 12-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 TSC_c18710 ff5245d54e9f169cd396b6da68043d33 437 Gene3D G3DSA:3.50.50.60 287 436 1.3E-51 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c18710 ff5245d54e9f169cd396b6da68043d33 437 Gene3D G3DSA:3.50.50.60 1 181 6.2E-56 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c18710 ff5245d54e9f169cd396b6da68043d33 437 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 4 430 34.292 T 12-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 TSC_c18710 ff5245d54e9f169cd396b6da68043d33 437 SUPERFAMILY SSF51905 3 359 7.5E-24 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c18710 ff5245d54e9f169cd396b6da68043d33 437 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 3 429 1.3E-189 T 12-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 TSC_c18710 ff5245d54e9f169cd396b6da68043d33 437 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 334 357 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 TSC_c09400 f08289dc6548766baf34de83e9c58c2f 433 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 94 108 2.9E-9 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c09400 f08289dc6548766baf34de83e9c58c2f 433 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 227 242 2.9E-9 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c09400 f08289dc6548766baf34de83e9c58c2f 433 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 167 186 2.9E-9 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c09400 f08289dc6548766baf34de83e9c58c2f 433 SUPERFAMILY SSF53738 1 158 5.1E-43 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c09400 f08289dc6548766baf34de83e9c58c2f 433 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 252 354 8.2E-30 T 12-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c09400 f08289dc6548766baf34de83e9c58c2f 433 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 428 2.0E-165 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c09400 f08289dc6548766baf34de83e9c58c2f 433 Gene3D G3DSA:3.40.120.10 250 327 1.5E-58 T 12-10-2018 TSC_c09400 f08289dc6548766baf34de83e9c58c2f 433 SUPERFAMILY SSF53738 153 249 2.32E-24 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c09400 f08289dc6548766baf34de83e9c58c2f 433 SUPERFAMILY SSF53738 251 353 1.92E-28 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c09400 f08289dc6548766baf34de83e9c58c2f 433 Gene3D G3DSA:3.30.310.50 358 431 5.1E-23 T 12-10-2018 TSC_c09400 f08289dc6548766baf34de83e9c58c2f 433 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 247 1.3E-12 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c09400 f08289dc6548766baf34de83e9c58c2f 433 SUPERFAMILY SSF55957 346 429 3.01E-22 T 12-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c09400 f08289dc6548766baf34de83e9c58c2f 433 Gene3D G3DSA:3.40.120.10 167 347 1.5E-58 T 12-10-2018 TSC_c09400 f08289dc6548766baf34de83e9c58c2f 433 Gene3D G3DSA:3.40.120.10 1 148 3.0E-49 T 12-10-2018 TSC_c09400 f08289dc6548766baf34de83e9c58c2f 433 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 430 43.224 T 12-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c09400 f08289dc6548766baf34de83e9c58c2f 433 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 2 136 8.7E-45 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c09400 f08289dc6548766baf34de83e9c58c2f 433 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 361 427 1.1E-13 T 12-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 423 607 2.8E-28 T 12-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 SUPERFAMILY SSF52518 792 1162 3.17E-119 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 TIGRFAM TIGR02176 pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase 5 1161 0.0 T 12-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 Gene3D G3DSA:3.40.920.10 414 621 3.2E-72 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 686 697 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 PIRSF PIRSF000159 1 1166 0.0 T 12-10-2018 IPR011895 Pyruvate-flavodoxin oxidoreductase GO:0005506|GO:0016903|GO:0022900|GO:0055114 TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 Gene3D G3DSA:4.10.780.10 624 665 4.7E-6 T 12-10-2018 IPR037112 Pyruvate-flavodoxin oxidoreductase, EKR domain superfamily TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 Pfam PF10371 Domain of unknown function 622 675 3.3E-21 T 12-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 15 245 2.4E-74 T 12-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 SUPERFAMILY SSF53323 416 665 3.79E-72 T 12-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 Gene3D G3DSA:3.40.50.920 258 411 3.8E-53 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 Gene3D G3DSA:3.40.50.970 792 1163 3.0E-146 T 12-10-2018 TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 SUPERFAMILY SSF54862 662 834 5.23E-21 T 12-10-2018 TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 SUPERFAMILY SSF52518 1 256 5.59E-73 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 Gene3D G3DSA:3.30.70.20 666 787 3.6E-35 T 12-10-2018 TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 957 1067 5.0E-10 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 741 752 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 Pfam PF13484 4Fe-4S double cluster binding domain 686 753 1.3E-9 T 12-10-2018 TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 267 349 3.2E-13 T 12-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 SUPERFAMILY SSF52922 258 409 6.0E-45 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 SMART SM00890 619 676 9.4E-30 T 12-10-2018 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain GO:0016903|GO:0055114 TSC_c13110 228ffe35fec21eb0a5717420dc29e9b6 1167 Gene3D G3DSA:3.40.50.970 2 256 9.1E-105 T 12-10-2018 TSC_c13840 0faec49bbcd8f718d8276af9e7f02b60 206 Gene3D G3DSA:3.40.50.2300 11 142 1.7E-30 T 12-10-2018 TSC_c13840 0faec49bbcd8f718d8276af9e7f02b60 206 SMART SM00448 13 125 1.0E-31 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c13840 0faec49bbcd8f718d8276af9e7f02b60 206 Gene3D G3DSA:1.10.10.10 143 203 4.8E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c13840 0faec49bbcd8f718d8276af9e7f02b60 206 SUPERFAMILY SSF52172 11 136 1.99E-31 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c13840 0faec49bbcd8f718d8276af9e7f02b60 206 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 195 2.5E-17 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c13840 0faec49bbcd8f718d8276af9e7f02b60 206 SUPERFAMILY SSF46894 136 203 2.21E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSC_c13840 0faec49bbcd8f718d8276af9e7f02b60 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 1.7E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c13840 0faec49bbcd8f718d8276af9e7f02b60 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 1.7E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c13840 0faec49bbcd8f718d8276af9e7f02b60 206 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 1.7E-12 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c13840 0faec49bbcd8f718d8276af9e7f02b60 206 Pfam PF00072 Response regulator receiver domain 15 125 2.2E-24 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c13840 0faec49bbcd8f718d8276af9e7f02b60 206 SMART SM00421 140 197 3.4E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 SUPERFAMILY SSF52540 159 404 2.82E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 560 578 6.5E-36 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 486 504 6.5E-36 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 531 549 6.5E-36 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 593 607 6.5E-36 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 486 499 - T 12-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 336 5.2E-14 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 292 304 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 Gene3D G3DSA:1.10.8.60 647 737 8.6E-12 T 12-10-2018 TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 Pfam PF07724 AAA domain (Cdc48 subfamily) 484 641 2.0E-45 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 Gene3D G3DSA:3.40.50.300 437 645 3.9E-76 T 12-10-2018 TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 647 717 2.3E-13 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 SMART SM00382 198 341 1.5E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 SMART SM00382 482 648 1.6E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 Gene3D G3DSA:1.10.8.60 340 436 3.9E-27 T 12-10-2018 TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 21 72 2.7E-13 T 12-10-2018 IPR004176 Clp, N-terminal TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 96 146 8.9E-12 T 12-10-2018 IPR004176 Clp, N-terminal TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 SUPERFAMILY SSF81923 8 151 6.41E-23 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 Gene3D G3DSA:1.10.1780.10 6 151 3.5E-41 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 SMART SM01086 647 732 2.9E-17 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 Gene3D G3DSA:3.40.50.300 152 339 7.5E-71 T 12-10-2018 TSC_c08090 17e626c06ec9b7e85a366ad3008bdce7 742 SUPERFAMILY SSF52540 440 709 3.71E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c04920 75cb1a69d4e542c01df40d5db161b0b1 805 Gene3D G3DSA:1.10.268.10 363 451 6.5E-205 T 12-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TSC_c04920 75cb1a69d4e542c01df40d5db161b0b1 805 Gene3D G3DSA:2.120.10.90 490 802 7.2E-114 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal TSC_c04920 75cb1a69d4e542c01df40d5db161b0b1 805 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 5 798 0.0 T 12-10-2018 TSC_c04920 75cb1a69d4e542c01df40d5db161b0b1 805 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 28 459 1.4E-155 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSC_c04920 75cb1a69d4e542c01df40d5db161b0b1 805 Gene3D G3DSA:3.90.199.10 28 480 6.5E-205 T 12-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 TSC_c04920 75cb1a69d4e542c01df40d5db161b0b1 805 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 1 803 23.725 T 12-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 TSC_c04920 75cb1a69d4e542c01df40d5db161b0b1 805 SMART SM00434 7 458 2.3E-267 T 12-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSC_c04920 75cb1a69d4e542c01df40d5db161b0b1 805 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 705 751 2.5E-11 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TSC_c04920 75cb1a69d4e542c01df40d5db161b0b1 805 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 547 596 9.8E-13 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TSC_c04920 75cb1a69d4e542c01df40d5db161b0b1 805 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 498 543 1.1E-11 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TSC_c04920 75cb1a69d4e542c01df40d5db161b0b1 805 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 604 646 3.6E-9 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TSC_c04920 75cb1a69d4e542c01df40d5db161b0b1 805 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 651 698 3.3E-12 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TSC_c04920 75cb1a69d4e542c01df40d5db161b0b1 805 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 756 801 3.6E-14 T 12-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 TSC_c04920 75cb1a69d4e542c01df40d5db161b0b1 805 Gene3D G3DSA:3.30.1360.40 231 326 6.5E-205 T 12-10-2018 TSC_c04920 75cb1a69d4e542c01df40d5db161b0b1 805 SUPERFAMILY SSF56719 26 480 6.8E-172 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TSC_c04920 75cb1a69d4e542c01df40d5db161b0b1 805 SUPERFAMILY SSF101904 492 803 3.4E-95 T 12-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal TSC_c24660 3bdff1a223c894afc01cd0e0be64f392 349 PIRSF PIRSF006004 1 343 3.3E-131 T 12-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 TSC_c24660 3bdff1a223c894afc01cd0e0be64f392 349 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 1 336 67.919 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 TSC_c24660 3bdff1a223c894afc01cd0e0be64f392 349 Gene3D G3DSA:3.20.20.70 58 321 5.1E-98 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c24660 3bdff1a223c894afc01cd0e0be64f392 349 Gene3D G3DSA:1.10.150.530 2 54 7.3E-11 T 12-10-2018 TSC_c24660 3bdff1a223c894afc01cd0e0be64f392 349 SUPERFAMILY SSF102114 89 304 2.09E-19 T 12-10-2018 TSC_c24660 3bdff1a223c894afc01cd0e0be64f392 349 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 14 332 1.3E-111 T 12-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 TSC_c24660 3bdff1a223c894afc01cd0e0be64f392 349 SMART SM00729 93 314 0.0042 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSC_c24660 3bdff1a223c894afc01cd0e0be64f392 349 Pfam PF04055 Radical SAM superfamily 98 265 1.6E-17 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSC_c23170 29279da65980d0ba90b4798dad42ce6b 331 Gene3D G3DSA:3.40.190.10 25 299 1.3E-115 T 12-10-2018 TSC_c23170 29279da65980d0ba90b4798dad42ce6b 331 Pfam PF13416 Bacterial extracellular solute-binding protein 39 296 1.4E-22 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSC_c23170 29279da65980d0ba90b4798dad42ce6b 331 SUPERFAMILY SSF53850 20 316 1.54E-65 T 12-10-2018 TSC_c23170 29279da65980d0ba90b4798dad42ce6b 331 Gene3D G3DSA:3.40.190.10 119 313 1.3E-115 T 12-10-2018 TSC_c23170 29279da65980d0ba90b4798dad42ce6b 331 PIRSF PIRSF002825 2 331 1.6E-75 T 12-10-2018 IPR026045 Ferric binding protein TSC_c15200 bb142e159da233137ccac582552685bb 374 Pfam PF01926 50S ribosome-binding GTPase 4 118 6.3E-23 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c15200 bb142e159da233137ccac582552685bb 374 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 1 374 43.974 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 TSC_c15200 bb142e159da233137ccac582552685bb 374 SUPERFAMILY SSF81271 290 370 1.87E-34 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TSC_c15200 bb142e159da233137ccac582552685bb 374 PIRSF PIRSF006641 1 374 1.3E-145 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 TSC_c15200 bb142e159da233137ccac582552685bb 374 Gene3D G3DSA:3.40.50.300 4 291 3.0E-144 T 12-10-2018 TSC_c15200 bb142e159da233137ccac582552685bb 374 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 2 374 1.8E-128 T 12-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 TSC_c15200 bb142e159da233137ccac582552685bb 374 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 8.8E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c15200 bb142e159da233137ccac582552685bb 374 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 73 88 8.8E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c15200 bb142e159da233137ccac582552685bb 374 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 90 108 8.8E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c15200 bb142e159da233137ccac582552685bb 374 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 8.8E-34 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c15200 bb142e159da233137ccac582552685bb 374 SUPERFAMILY SSF52540 3 312 1.01E-76 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c15200 bb142e159da233137ccac582552685bb 374 Gene3D G3DSA:3.10.20.30 47 368 3.0E-144 T 12-10-2018 IPR012675 Beta-grasp domain superfamily TSC_c15200 bb142e159da233137ccac582552685bb 374 Pfam PF06071 Protein of unknown function (DUF933) 290 373 6.5E-37 T 12-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 TSC_c15200 bb142e159da233137ccac582552685bb 374 Gene3D G3DSA:1.10.150.300 126 210 3.0E-144 T 12-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 TSC_c19650 833e08ac681f43a989941285cca9e83b 73 SUPERFAMILY SSF54285 10 65 5.23E-10 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TSC_c19650 833e08ac681f43a989941285cca9e83b 73 Gene3D G3DSA:3.10.20.30 1 65 3.5E-16 T 12-10-2018 IPR012675 Beta-grasp domain superfamily TSC_c06400 6c37055b3187081ea2bce63237059510 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 60 2.6E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSC_c06400 6c37055b3187081ea2bce63237059510 298 SUPERFAMILY SSF46785 1 109 4.13E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c06400 6c37055b3187081ea2bce63237059510 298 Pfam PF03466 LysR substrate binding domain 87 288 6.6E-43 T 12-10-2018 IPR005119 LysR, substrate-binding TSC_c06400 6c37055b3187081ea2bce63237059510 298 SUPERFAMILY SSF53850 88 295 8.47E-40 T 12-10-2018 TSC_c06400 6c37055b3187081ea2bce63237059510 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.5E-12 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSC_c06400 6c37055b3187081ea2bce63237059510 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.5E-12 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSC_c06400 6c37055b3187081ea2bce63237059510 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.5E-12 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSC_c06400 6c37055b3187081ea2bce63237059510 298 Gene3D G3DSA:3.40.190.10 159 259 5.9E-61 T 12-10-2018 TSC_c06400 6c37055b3187081ea2bce63237059510 298 Gene3D G3DSA:3.40.190.10 89 285 5.9E-61 T 12-10-2018 TSC_c06400 6c37055b3187081ea2bce63237059510 298 Gene3D G3DSA:1.10.10.10 1 82 1.1E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c20190 68b0603d1887080ae5b3c78936bbf729 441 Gene3D G3DSA:3.65.10.10 16 432 1.7E-138 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TSC_c20190 68b0603d1887080ae5b3c78936bbf729 441 SUPERFAMILY SSF55205 10 437 1.21E-116 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TSC_c20190 68b0603d1887080ae5b3c78936bbf729 441 PIRSF PIRSF000505 10 441 2.8E-113 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TSC_c20190 68b0603d1887080ae5b3c78936bbf729 441 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 16 438 9.0E-115 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TSC_c20190 68b0603d1887080ae5b3c78936bbf729 441 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 12 440 32.992 T 12-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TSC_c20190 68b0603d1887080ae5b3c78936bbf729 441 Gene3D G3DSA:3.65.10.10 24 244 1.7E-138 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TSC_c20190 68b0603d1887080ae5b3c78936bbf729 441 ProSitePatterns PS00885 EPSP synthase signature 2. 354 372 - T 12-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 TSC_c20190 68b0603d1887080ae5b3c78936bbf729 441 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 13 434 1.0E-109 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 TSC_c01770 212cb6a3868cdf4da6931c1c0d682a76 184 SMART SM00738 2 116 1.6E-49 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TSC_c01770 212cb6a3868cdf4da6931c1c0d682a76 184 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 184 26.004 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TSC_c01770 212cb6a3868cdf4da6931c1c0d682a76 184 SUPERFAMILY SSF50104 114 183 3.35E-20 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily TSC_c01770 212cb6a3868cdf4da6931c1c0d682a76 184 Gene3D G3DSA:2.30.30.30 124 183 2.3E-27 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 TSC_c01770 212cb6a3868cdf4da6931c1c0d682a76 184 PRINTS PR00338 Transcription termination factor NUSG signature 160 176 1.4E-21 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TSC_c01770 212cb6a3868cdf4da6931c1c0d682a76 184 PRINTS PR00338 Transcription termination factor NUSG signature 58 70 1.4E-21 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TSC_c01770 212cb6a3868cdf4da6931c1c0d682a76 184 PRINTS PR00338 Transcription termination factor NUSG signature 142 157 1.4E-21 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TSC_c01770 212cb6a3868cdf4da6931c1c0d682a76 184 Gene3D G3DSA:3.30.70.940 2 120 1.6E-47 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TSC_c01770 212cb6a3868cdf4da6931c1c0d682a76 184 Pfam PF02357 Transcription termination factor nusG 4 113 2.0E-25 T 12-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TSC_c01770 212cb6a3868cdf4da6931c1c0d682a76 184 SUPERFAMILY SSF82679 4 114 5.36E-40 T 12-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 TSC_c01770 212cb6a3868cdf4da6931c1c0d682a76 184 SMART SM00739 130 157 3.9E-8 T 12-10-2018 IPR005824 KOW TSC_c01770 212cb6a3868cdf4da6931c1c0d682a76 184 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 183 3.3E-62 T 12-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 TSC_c01770 212cb6a3868cdf4da6931c1c0d682a76 184 ProSitePatterns PS01014 Transcription termination factor nusG signature. 167 176 - T 12-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site TSC_c01770 212cb6a3868cdf4da6931c1c0d682a76 184 Pfam PF00467 KOW motif 133 164 3.7E-10 T 12-10-2018 IPR005824 KOW TSC_c23330 204ce4c1425bc21808fce17de306acd4 214 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 39 210 2.5E-45 T 12-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG TSC_c23330 204ce4c1425bc21808fce17de306acd4 214 Gene3D G3DSA:3.40.50.450 15 212 4.3E-73 T 12-10-2018 TSC_c23330 204ce4c1425bc21808fce17de306acd4 214 Pfam PF03641 Possible lysine decarboxylase 81 209 2.1E-33 T 12-10-2018 IPR031100 LOG family TSC_c23330 204ce4c1425bc21808fce17de306acd4 214 SUPERFAMILY SSF102405 7 211 1.08E-66 T 12-10-2018 TSC_c22200 3bd64c1bb2b9299d09500f310ac79f35 126 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 12-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22200 3bd64c1bb2b9299d09500f310ac79f35 126 Gene3D G3DSA:4.10.910.10 73 126 6.4E-30 T 12-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22200 3bd64c1bb2b9299d09500f310ac79f35 126 SUPERFAMILY SSF46946 2 123 3.66E-49 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TSC_c22200 3bd64c1bb2b9299d09500f310ac79f35 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 1.2E-32 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22200 3bd64c1bb2b9299d09500f310ac79f35 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 7.3E-54 T 12-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22200 3bd64c1bb2b9299d09500f310ac79f35 126 Gene3D G3DSA:1.10.8.50 1 72 1.8E-30 T 12-10-2018 TSC_c22200 3bd64c1bb2b9299d09500f310ac79f35 126 PIRSF PIRSF002134 1 125 5.5E-47 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22200 3bd64c1bb2b9299d09500f310ac79f35 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 119 27.234 T 12-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c10260 b45fe246a3b1856e727ea4d2c53fe268 499 SUPERFAMILY SSF52335 4 187 3.92E-61 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TSC_c10260 b45fe246a3b1856e727ea4d2c53fe268 499 SMART SM00851 15 126 1.1E-45 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain TSC_c10260 b45fe246a3b1856e727ea4d2c53fe268 499 Pfam PF02142 MGS-like domain 15 125 8.6E-21 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain TSC_c10260 b45fe246a3b1856e727ea4d2c53fe268 499 Gene3D G3DSA:3.40.140.20 195 350 3.7E-59 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSC_c10260 b45fe246a3b1856e727ea4d2c53fe268 499 SUPERFAMILY SSF53927 200 499 1.1E-121 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TSC_c10260 b45fe246a3b1856e727ea4d2c53fe268 499 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 3 499 42.672 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSC_c10260 b45fe246a3b1856e727ea4d2c53fe268 499 SMART SM00798 131 438 2.5E-188 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSC_c10260 b45fe246a3b1856e727ea4d2c53fe268 499 PIRSF PIRSF000414 1 499 1.6E-199 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSC_c10260 b45fe246a3b1856e727ea4d2c53fe268 499 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 6 499 3.1E-186 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSC_c10260 b45fe246a3b1856e727ea4d2c53fe268 499 Gene3D G3DSA:3.40.140.20 366 499 3.2E-55 T 12-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSC_c10260 b45fe246a3b1856e727ea4d2c53fe268 499 Gene3D G3DSA:3.40.50.1380 1 191 2.7E-77 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TSC_c10260 b45fe246a3b1856e727ea4d2c53fe268 499 Pfam PF01808 AICARFT/IMPCHase bienzyme 131 432 1.1E-113 T 12-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSC_c14550 f64ddaf31696289e54e675f98383bb4b 414 Pfam PF14450 Cell division protein FtsA 202 368 5.9E-23 T 12-10-2018 TSC_c14550 f64ddaf31696289e54e675f98383bb4b 414 Gene3D G3DSA:3.30.1490.110 80 163 1.9E-100 T 12-10-2018 TSC_c14550 f64ddaf31696289e54e675f98383bb4b 414 SUPERFAMILY SSF53067 2 191 1.31E-52 T 12-10-2018 TSC_c14550 f64ddaf31696289e54e675f98383bb4b 414 PIRSF PIRSF003101 1 414 3.7E-126 T 12-10-2018 IPR020823 Cell division protein FtsA TSC_c14550 f64ddaf31696289e54e675f98383bb4b 414 Gene3D G3DSA:3.30.420.40 191 346 1.9E-100 T 12-10-2018 TSC_c14550 f64ddaf31696289e54e675f98383bb4b 414 SUPERFAMILY SSF53067 193 371 1.12E-39 T 12-10-2018 TSC_c14550 f64ddaf31696289e54e675f98383bb4b 414 Gene3D G3DSA:3.90.640.10 229 293 1.9E-100 T 12-10-2018 TSC_c14550 f64ddaf31696289e54e675f98383bb4b 414 Hamap MF_02033 Cell division protein FtsA [ftsA]. 1 414 28.134 T 12-10-2018 IPR020823 Cell division protein FtsA TSC_c14550 f64ddaf31696289e54e675f98383bb4b 414 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 3 372 5.8E-112 T 12-10-2018 IPR020823 Cell division protein FtsA TSC_c14550 f64ddaf31696289e54e675f98383bb4b 414 Pfam PF02491 SHS2 domain inserted in FTSA 78 155 5.2E-26 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 TSC_c14550 f64ddaf31696289e54e675f98383bb4b 414 Gene3D G3DSA:3.30.420.40 6 366 1.9E-100 T 12-10-2018 TSC_c14550 f64ddaf31696289e54e675f98383bb4b 414 SMART SM00842 3 190 1.4E-90 T 12-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 TSC_c18650 8deaf5fdf34f330662a83554c720dd5c 592 Pfam PF01541 GIY-YIG catalytic domain 17 87 3.7E-7 T 12-10-2018 IPR000305 GIY-YIG endonuclease TSC_c18650 8deaf5fdf34f330662a83554c720dd5c 592 SUPERFAMILY SSF46600 183 233 3.79E-13 T 12-10-2018 IPR036876 UVR domain superfamily TSC_c18650 8deaf5fdf34f330662a83554c720dd5c 592 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 377 519 1.1E-41 T 12-10-2018 IPR001162 UvrC family homology region TSC_c18650 8deaf5fdf34f330662a83554c720dd5c 592 SMART SM00465 15 92 1.6E-17 T 12-10-2018 IPR000305 GIY-YIG endonuclease TSC_c18650 8deaf5fdf34f330662a83554c720dd5c 592 SUPERFAMILY SSF82771 15 94 8.37E-18 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 TSC_c18650 8deaf5fdf34f330662a83554c720dd5c 592 Gene3D G3DSA:3.30.420.340 371 532 6.1E-46 T 12-10-2018 IPR038476 UvrC homology region 2 superfamily TSC_c18650 8deaf5fdf34f330662a83554c720dd5c 592 Gene3D G3DSA:3.40.1440.10 6 95 1.5E-29 T 12-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 TSC_c18650 8deaf5fdf34f330662a83554c720dd5c 592 SMART SM00278 567 586 1.7 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSC_c18650 8deaf5fdf34f330662a83554c720dd5c 592 SMART SM00278 535 554 45.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSC_c18650 8deaf5fdf34f330662a83554c720dd5c 592 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 586 27.276 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 TSC_c18650 8deaf5fdf34f330662a83554c720dd5c 592 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 8 568 3.1E-159 T 12-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 TSC_c18650 8deaf5fdf34f330662a83554c720dd5c 592 Pfam PF02151 UvrB/uvrC motif 199 231 3.0E-10 T 12-10-2018 IPR001943 UVR domain GO:0005515 TSC_c18650 8deaf5fdf34f330662a83554c720dd5c 592 SUPERFAMILY SSF47781 501 588 8.58E-16 T 12-10-2018 IPR010994 RuvA domain 2-like TSC_c18650 8deaf5fdf34f330662a83554c720dd5c 592 Gene3D G3DSA:1.10.150.20 536 588 2.0E-15 T 12-10-2018 TSC_c18650 8deaf5fdf34f330662a83554c720dd5c 592 Pfam PF14520 Helix-hairpin-helix domain 534 587 3.2E-7 T 12-10-2018 TSC_c18650 8deaf5fdf34f330662a83554c720dd5c 592 Gene3D G3DSA:4.10.860.10 181 236 3.5E-9 T 12-10-2018 TSC_c05570 a75ada22ffc80e4b1d9f4fbc55eff6ad 298 SUPERFAMILY SSF53738 143 248 2.67E-17 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c05570 a75ada22ffc80e4b1d9f4fbc55eff6ad 298 SUPERFAMILY SSF53738 6 128 3.14E-19 T 12-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c05570 a75ada22ffc80e4b1d9f4fbc55eff6ad 298 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 144 243 4.9E-16 T 12-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c05570 a75ada22ffc80e4b1d9f4fbc55eff6ad 298 Gene3D G3DSA:3.40.120.10 162 246 4.4E-17 T 12-10-2018 TSC_c05570 a75ada22ffc80e4b1d9f4fbc55eff6ad 298 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 161 180 3.7E-7 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c05570 a75ada22ffc80e4b1d9f4fbc55eff6ad 298 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 226 241 3.7E-7 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c05570 a75ada22ffc80e4b1d9f4fbc55eff6ad 298 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 197 210 3.7E-7 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c05570 a75ada22ffc80e4b1d9f4fbc55eff6ad 298 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 92 106 3.7E-7 T 12-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c05570 a75ada22ffc80e4b1d9f4fbc55eff6ad 298 Gene3D G3DSA:3.40.120.10 3 140 2.0E-22 T 12-10-2018 TSC_c05570 a75ada22ffc80e4b1d9f4fbc55eff6ad 298 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 7 121 1.2E-17 T 12-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 TSC_c19910 583f9f511fd62252f48bd1efa42df083 379 SUPERFAMILY SSF48371 141 348 6.81E-23 T 12-10-2018 IPR016024 Armadillo-type fold TSC_c19910 583f9f511fd62252f48bd1efa42df083 379 Gene3D G3DSA:1.25.10.110 295 376 1.3E-7 T 12-10-2018 TSC_c19910 583f9f511fd62252f48bd1efa42df083 379 Pfam PF13646 HEAT repeats 296 359 1.8E-7 T 12-10-2018 TSC_c19910 583f9f511fd62252f48bd1efa42df083 379 Gene3D G3DSA:1.25.10.10 107 294 4.0E-8 T 12-10-2018 IPR011989 Armadillo-like helical TSC_c15640 ea4f9fb2a21fd283cb94717c0678356e 523 SUPERFAMILY SSF53335 5 514 2.22E-122 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c15640 ea4f9fb2a21fd283cb94717c0678356e 523 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 180 196 5.4E-17 T 12-10-2018 TSC_c15640 ea4f9fb2a21fd283cb94717c0678356e 523 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 293 305 5.4E-17 T 12-10-2018 TSC_c15640 ea4f9fb2a21fd283cb94717c0678356e 523 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 328 352 5.4E-17 T 12-10-2018 TSC_c15640 ea4f9fb2a21fd283cb94717c0678356e 523 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 204 218 5.4E-17 T 12-10-2018 TSC_c15640 ea4f9fb2a21fd283cb94717c0678356e 523 Pfam PF12161 HsdM N-terminal domain 6 144 3.5E-31 T 12-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain TSC_c15640 ea4f9fb2a21fd283cb94717c0678356e 523 Gene3D G3DSA:1.20.1260.30 1 148 6.3E-24 T 12-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily TSC_c15640 ea4f9fb2a21fd283cb94717c0678356e 523 Pfam PF02384 N-6 DNA Methylase 157 482 8.2E-94 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TSC_c15640 ea4f9fb2a21fd283cb94717c0678356e 523 Gene3D G3DSA:3.40.50.150 157 466 2.3E-89 T 12-10-2018 TSC_c10380 3fef31e8a2208655497a52e32a761441 227 Gene3D G3DSA:3.40.50.300 2 225 4.9E-69 T 12-10-2018 TSC_c10380 3fef31e8a2208655497a52e32a761441 227 SUPERFAMILY SSF52540 3 224 5.03E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c10380 3fef31e8a2208655497a52e32a761441 227 Pfam PF00005 ABC transporter 23 172 4.8E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c10380 3fef31e8a2208655497a52e32a761441 227 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c10380 3fef31e8a2208655497a52e32a761441 227 SMART SM00382 32 220 1.2E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c08310 6ff1107614fa18f7365cb2ab6a2fdef4 118 SUPERFAMILY SSF74731 2 116 2.88E-46 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c08310 6ff1107614fa18f7365cb2ab6a2fdef4 118 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 2.8E-49 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c08310 6ff1107614fa18f7365cb2ab6a2fdef4 118 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c08310 6ff1107614fa18f7365cb2ab6a2fdef4 118 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 20 72 2.0E-17 T 12-10-2018 TSC_c08310 6ff1107614fa18f7365cb2ab6a2fdef4 118 Gene3D G3DSA:1.10.720.90 2 55 2.3E-21 T 12-10-2018 TSC_c08310 6ff1107614fa18f7365cb2ab6a2fdef4 118 Gene3D G3DSA:1.10.1900.20 56 117 1.2E-32 T 12-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c08310 6ff1107614fa18f7365cb2ab6a2fdef4 118 PRINTS PR00062 Ribosomal protein L20 signature 12 41 6.6E-37 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c08310 6ff1107614fa18f7365cb2ab6a2fdef4 118 PRINTS PR00062 Ribosomal protein L20 signature 75 101 6.6E-37 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c08310 6ff1107614fa18f7365cb2ab6a2fdef4 118 PRINTS PR00062 Ribosomal protein L20 signature 42 71 6.6E-37 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c08310 6ff1107614fa18f7365cb2ab6a2fdef4 118 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 28.719 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c08310 6ff1107614fa18f7365cb2ab6a2fdef4 118 Pfam PF00453 Ribosomal protein L20 3 109 1.7E-46 T 12-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c19840 49db9c20804a9d51c65dd233983e909a 952 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 3 927 0.0 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 TSC_c19840 49db9c20804a9d51c65dd233983e909a 952 SUPERFAMILY SSF52540 618 912 2.9E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c19840 49db9c20804a9d51c65dd233983e909a 952 Pfam PF00005 ABC transporter 626 862 3.2E-10 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c19840 49db9c20804a9d51c65dd233983e909a 952 Gene3D G3DSA:1.20.1580.10 695 832 2.3E-145 T 12-10-2018 TSC_c19840 49db9c20804a9d51c65dd233983e909a 952 Gene3D G3DSA:1.20.1580.10 90 496 7.0E-249 T 12-10-2018 TSC_c19840 49db9c20804a9d51c65dd233983e909a 952 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c19840 49db9c20804a9d51c65dd233983e909a 952 Gene3D G3DSA:3.40.50.300 617 937 2.3E-145 T 12-10-2018 TSC_c19840 49db9c20804a9d51c65dd233983e909a 952 SUPERFAMILY SSF52540 6 573 4.46E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c19840 49db9c20804a9d51c65dd233983e909a 952 SUPERFAMILY SSF52540 8 338 9.19E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c19840 49db9c20804a9d51c65dd233983e909a 952 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 941 23.091 T 12-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 TSC_c19840 49db9c20804a9d51c65dd233983e909a 952 Gene3D G3DSA:3.30.190.20 130 244 7.0E-249 T 12-10-2018 TSC_c19840 49db9c20804a9d51c65dd233983e909a 952 SMART SM00382 635 908 7.5E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c19840 49db9c20804a9d51c65dd233983e909a 952 SMART SM00382 23 231 1.3 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c19840 49db9c20804a9d51c65dd233983e909a 952 ProSitePatterns PS00211 ABC transporters family signature. 832 846 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c19840 49db9c20804a9d51c65dd233983e909a 952 Gene3D G3DSA:3.40.50.300 5 598 7.0E-249 T 12-10-2018 TSC_c19840 49db9c20804a9d51c65dd233983e909a 952 Gene3D G3DSA:1.10.8.280 287 405 7.0E-249 T 12-10-2018 TSC_c03720 ce900c0106121edfa63ccd6771cab246 404 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 5 399 7.4E-171 T 12-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 TSC_c03720 ce900c0106121edfa63ccd6771cab246 404 Pfam PF00266 Aminotransferase class-V 20 389 2.4E-147 T 12-10-2018 IPR000192 Aminotransferase class V domain TSC_c03720 ce900c0106121edfa63ccd6771cab246 404 Gene3D G3DSA:3.40.640.10 31 290 1.1E-172 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c03720 ce900c0106121edfa63ccd6771cab246 404 SUPERFAMILY SSF53383 2 399 3.26E-128 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c03720 ce900c0106121edfa63ccd6771cab246 404 Gene3D G3DSA:3.90.1150.10 7 393 1.1E-172 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c15020 170cd04e21ab8eec766b3e23a6e58664 316 Pfam PF16868 NMT1-like family 25 313 2.0E-83 T 12-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TSC_c15020 170cd04e21ab8eec766b3e23a6e58664 316 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 16 313 5.6E-105 T 12-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TSC_c15020 170cd04e21ab8eec766b3e23a6e58664 316 Gene3D G3DSA:3.40.190.10 111 249 1.9E-118 T 12-10-2018 TSC_c15020 170cd04e21ab8eec766b3e23a6e58664 316 SUPERFAMILY SSF53850 20 315 2.12E-83 T 12-10-2018 TSC_c15020 170cd04e21ab8eec766b3e23a6e58664 316 Gene3D G3DSA:3.40.190.10 25 313 1.9E-118 T 12-10-2018 TSC_c06370 c516edec114c64f5885be21a1a1392cc 301 SUPERFAMILY SSF52540 10 206 2.17E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c06370 c516edec114c64f5885be21a1a1392cc 301 Gene3D G3DSA:3.40.50.300 1 184 5.3E-53 T 12-10-2018 TSC_c06370 c516edec114c64f5885be21a1a1392cc 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 10 30 2.3E-6 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c06370 c516edec114c64f5885be21a1a1392cc 301 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 77 95 2.3E-6 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c06370 c516edec114c64f5885be21a1a1392cc 301 SUPERFAMILY SSF54814 185 297 2.09E-37 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TSC_c06370 c516edec114c64f5885be21a1a1392cc 301 Gene3D G3DSA:3.30.300.20 185 301 1.9E-42 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TSC_c06370 c516edec114c64f5885be21a1a1392cc 301 Pfam PF01926 50S ribosome-binding GTPase 10 126 2.6E-22 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c06370 c516edec114c64f5885be21a1a1392cc 301 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 145 8.5E-25 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSC_c06370 c516edec114c64f5885be21a1a1392cc 301 Pfam PF07650 KH domain 208 285 1.2E-19 T 12-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c06370 c516edec114c64f5885be21a1a1392cc 301 Hamap MF_00367 GTPase Era [era]. 5 296 33.51 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c06370 c516edec114c64f5885be21a1a1392cc 301 TIGRFAM TIGR00436 era: GTP-binding protein Era 8 279 4.3E-72 T 12-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c00760 ad891db18350d2343a0c68a5112f021b 186 SUPERFAMILY SSF100950 5 185 1.93E-15 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TSC_c00760 ad891db18350d2343a0c68a5112f021b 186 Gene3D G3DSA:3.40.50.10420 35 185 1.0E-8 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily TSC_c00760 ad891db18350d2343a0c68a5112f021b 186 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 5 150 3.9E-11 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase TSC_c11430 58d660e8d3d3fb87e56cad85c010ac9b 222 SUPERFAMILY SSF89562 12 174 2.35E-39 T 12-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily TSC_c11430 58d660e8d3d3fb87e56cad85c010ac9b 222 Pfam PF03737 Aldolase/RraA 17 163 1.4E-31 T 12-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein TSC_c11430 58d660e8d3d3fb87e56cad85c010ac9b 222 Gene3D G3DSA:3.50.30.100 3 186 3.7E-46 T 12-10-2018 TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 PIRSF PIRSF001400 1 422 7.4E-190 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 SMART SM01192 138 420 5.3E-220 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 PRINTS PR00148 Enolase signature 37 51 9.1E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 PRINTS PR00148 Enolase signature 362 379 9.1E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 PRINTS PR00148 Enolase signature 333 347 9.1E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 PRINTS PR00148 Enolase signature 310 321 9.1E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 PRINTS PR00148 Enolase signature 106 122 9.1E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 PRINTS PR00148 Enolase signature 160 173 9.1E-47 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 Pfam PF03952 Enolase, N-terminal domain 4 133 3.0E-56 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 ProSitePatterns PS00164 Enolase signature. 333 346 - T 12-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 422 4.8E-208 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 Pfam PF00113 Enolase, C-terminal TIM barrel domain 139 420 1.7E-129 T 12-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 SUPERFAMILY SSF54826 3 136 2.36E-53 T 12-10-2018 TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 SUPERFAMILY SSF51604 138 421 2.75E-128 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 Hamap MF_00318 Enolase [eno]. 2 410 46.502 T 12-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 Gene3D G3DSA:3.20.20.120 127 422 8.6E-137 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 SMART SM01193 4 133 4.9E-90 T 12-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 TSC_c00030 cbec0c6520cf58f86c57b59bbf668a52 422 Gene3D G3DSA:3.30.390.10 1 126 1.3E-51 T 12-10-2018 IPR029017 Enolase-like, N-terminal TSC_c03070 26429938c2514b59c175410f798e8f28 85 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 85 8.0E-26 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c03070 26429938c2514b59c175410f798e8f28 85 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 84 28.432 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c03070 26429938c2514b59c175410f798e8f28 85 SUPERFAMILY SSF110324 2 82 1.26E-33 T 12-10-2018 TSC_c03070 26429938c2514b59c175410f798e8f28 85 PRINTS PR00063 Ribosomal protein L27 signature 29 53 6.8E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c03070 26429938c2514b59c175410f798e8f28 85 PRINTS PR00063 Ribosomal protein L27 signature 54 78 6.8E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c03070 26429938c2514b59c175410f798e8f28 85 PRINTS PR00063 Ribosomal protein L27 signature 4 28 6.8E-37 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c03070 26429938c2514b59c175410f798e8f28 85 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 12-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c03070 26429938c2514b59c175410f798e8f28 85 Pfam PF01016 Ribosomal L27 protein 2 81 4.8E-38 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c03070 26429938c2514b59c175410f798e8f28 85 Gene3D G3DSA:2.40.50.100 20 85 1.7E-32 T 12-10-2018 TSC_c03070 26429938c2514b59c175410f798e8f28 85 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 77 4.0E-38 T 12-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c02690 4b3ac0e17b0ad1d5d4cb603ca5366474 402 SUPERFAMILY SSF47005 94 139 2.09E-10 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TSC_c02690 4b3ac0e17b0ad1d5d4cb603ca5366474 402 Pfam PF00364 Biotin-requiring enzyme 3 74 5.2E-17 T 12-10-2018 IPR000089 Biotin/lipoyl attachment TSC_c02690 4b3ac0e17b0ad1d5d4cb603ca5366474 402 SUPERFAMILY SSF51230 2 87 2.49E-21 T 12-10-2018 IPR011053 Single hybrid motif TSC_c02690 4b3ac0e17b0ad1d5d4cb603ca5366474 402 Gene3D G3DSA:3.30.559.10 171 402 1.1E-95 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TSC_c02690 4b3ac0e17b0ad1d5d4cb603ca5366474 402 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 174 400 1.1E-81 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 TSC_c02690 4b3ac0e17b0ad1d5d4cb603ca5366474 402 Pfam PF02817 e3 binding domain 100 135 1.4E-11 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 TSC_c02690 4b3ac0e17b0ad1d5d4cb603ca5366474 402 SUPERFAMILY SSF52777 174 401 3.11E-88 T 12-10-2018 TSC_c02690 4b3ac0e17b0ad1d5d4cb603ca5366474 402 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TSC_c02690 4b3ac0e17b0ad1d5d4cb603ca5366474 402 Gene3D G3DSA:4.10.320.10 96 140 9.0E-13 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TSC_c02690 4b3ac0e17b0ad1d5d4cb603ca5366474 402 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 3 402 7.6E-146 T 12-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 TSC_c02690 4b3ac0e17b0ad1d5d4cb603ca5366474 402 Gene3D G3DSA:2.40.50.100 1 95 7.2E-20 T 12-10-2018 TSC_c19070 af17e9fccd726bc0b8341642a889906a 560 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 12-10-2018 IPR020845 AMP-binding, conserved site TSC_c19070 af17e9fccd726bc0b8341642a889906a 560 Pfam PF00501 AMP-binding enzyme 32 458 1.1E-120 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSC_c19070 af17e9fccd726bc0b8341642a889906a 560 Gene3D G3DSA:3.30.300.310 455 559 7.1E-36 T 12-10-2018 TSC_c19070 af17e9fccd726bc0b8341642a889906a 560 Gene3D G3DSA:3.40.50.12780 26 450 1.1E-132 T 12-10-2018 TSC_c19070 af17e9fccd726bc0b8341642a889906a 560 Pfam PF13193 AMP-binding enzyme C-terminal domain 468 545 3.2E-23 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSC_c19070 af17e9fccd726bc0b8341642a889906a 560 SUPERFAMILY SSF56801 14 557 2.88E-170 T 12-10-2018 TSC_c17280 c43bb6db90ae8cbf7bddaf78d6f630f3 185 SUPERFAMILY SSF46689 56 154 1.24E-8 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSC_c17280 c43bb6db90ae8cbf7bddaf78d6f630f3 185 Pfam PF13592 Winged helix-turn helix 121 178 8.8E-16 T 12-10-2018 IPR025959 Winged helix-turn helix domain TSC_c17280 c43bb6db90ae8cbf7bddaf78d6f630f3 185 Pfam PF13551 Winged helix-turn helix 54 100 6.2E-7 T 12-10-2018 TSC_c11790 8d7a7751c93251670f17081ba8484d15 576 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 49 109 6.5E-17 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSC_c11790 8d7a7751c93251670f17081ba8484d15 576 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 320 384 1.3E-17 T 12-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSC_c11790 8d7a7751c93251670f17081ba8484d15 576 Gene3D G3DSA:3.30.413.10 119 303 2.4E-90 T 12-10-2018 TSC_c11790 8d7a7751c93251670f17081ba8484d15 576 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 444 460 - T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSC_c11790 8d7a7751c93251670f17081ba8484d15 576 SUPERFAMILY SSF55124 251 407 1.96E-20 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSC_c11790 8d7a7751c93251670f17081ba8484d15 576 Gene3D G3DSA:3.30.413.10 391 567 1.5E-42 T 12-10-2018 TSC_c11790 8d7a7751c93251670f17081ba8484d15 576 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 394 540 6.1E-14 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSC_c11790 8d7a7751c93251670f17081ba8484d15 576 SUPERFAMILY SSF56014 120 275 5.37E-43 T 12-10-2018 TSC_c11790 8d7a7751c93251670f17081ba8484d15 576 SUPERFAMILY SSF55124 10 119 3.93E-25 T 12-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSC_c11790 8d7a7751c93251670f17081ba8484d15 576 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 120 269 1.7E-38 T 12-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSC_c11790 8d7a7751c93251670f17081ba8484d15 576 Gene3D G3DSA:3.90.480.10 52 375 2.4E-90 T 12-10-2018 TSC_c11790 8d7a7751c93251670f17081ba8484d15 576 SUPERFAMILY SSF56014 396 554 3.93E-36 T 12-10-2018 TSC_c11790 8d7a7751c93251670f17081ba8484d15 576 PRINTS PR00397 Sirohaem Fe-binding site signature 444 462 5.5E-7 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSC_c11790 8d7a7751c93251670f17081ba8484d15 576 PRINTS PR00397 Sirohaem Fe-binding site signature 396 414 5.5E-7 T 12-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 TSC_c05780 35a557278d73da9d3fc0b795aa8408ed 308 SUPERFAMILY SSF55174 11 63 1.9E-11 T 12-10-2018 TSC_c05780 35a557278d73da9d3fc0b795aa8408ed 308 SMART SM00363 12 74 6.2E-13 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c05780 35a557278d73da9d3fc0b795aa8408ed 308 SUPERFAMILY SSF55120 70 295 5.52E-70 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c05780 35a557278d73da9d3fc0b795aa8408ed 308 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 8 290 1.5E-78 T 12-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c05780 35a557278d73da9d3fc0b795aa8408ed 308 Pfam PF01479 S4 domain 12 57 1.9E-11 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c05780 35a557278d73da9d3fc0b795aa8408ed 308 Gene3D G3DSA:3.30.2350.10 66 284 9.4E-71 T 12-10-2018 TSC_c05780 35a557278d73da9d3fc0b795aa8408ed 308 Gene3D G3DSA:3.10.290.10 2 65 6.0E-16 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TSC_c05780 35a557278d73da9d3fc0b795aa8408ed 308 Pfam PF00849 RNA pseudouridylate synthase 83 237 8.8E-32 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c05780 35a557278d73da9d3fc0b795aa8408ed 308 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 131 145 - T 12-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c01550 f8edda2cd0558318b791a6b80e4d752b 888 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 45 148 1.2E-17 T 12-10-2018 IPR007831 General secretory system II, protein E, N-terminal TSC_c01550 f8edda2cd0558318b791a6b80e4d752b 888 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 173 303 1.8E-11 T 12-10-2018 IPR007831 General secretory system II, protein E, N-terminal TSC_c01550 f8edda2cd0558318b791a6b80e4d752b 888 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 369 479 6.8E-21 T 12-10-2018 IPR007831 General secretory system II, protein E, N-terminal TSC_c01550 f8edda2cd0558318b791a6b80e4d752b 888 SUPERFAMILY SSF52540 501 884 1.1E-98 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c01550 f8edda2cd0558318b791a6b80e4d752b 888 Gene3D G3DSA:3.30.300.160 393 476 6.4E-10 T 12-10-2018 TSC_c01550 f8edda2cd0558318b791a6b80e4d752b 888 SUPERFAMILY SSF160246 166 299 9.42E-21 T 12-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily TSC_c01550 f8edda2cd0558318b791a6b80e4d752b 888 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 706 720 - T 12-10-2018 IPR001482 Type II/IV secretion system protein TSC_c01550 f8edda2cd0558318b791a6b80e4d752b 888 Gene3D G3DSA:3.40.50.300 613 888 3.5E-126 T 12-10-2018 TSC_c01550 f8edda2cd0558318b791a6b80e4d752b 888 SUPERFAMILY SSF160246 332 476 3.27E-34 T 12-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily TSC_c01550 f8edda2cd0558318b791a6b80e4d752b 888 Gene3D G3DSA:3.30.450.90 477 611 1.1E-40 T 12-10-2018 TSC_c01550 f8edda2cd0558318b791a6b80e4d752b 888 Pfam PF00437 Type II/IV secretion system protein 515 778 8.9E-76 T 12-10-2018 IPR001482 Type II/IV secretion system protein TSC_c01550 f8edda2cd0558318b791a6b80e4d752b 888 SUPERFAMILY SSF160246 8 147 1.44E-32 T 12-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily TSC_c01190 95da42973905784b38af63858e89bbf6 285 Gene3D G3DSA:3.40.190.10 115 273 6.2E-41 T 12-10-2018 TSC_c01190 95da42973905784b38af63858e89bbf6 285 Gene3D G3DSA:1.10.10.10 1 89 8.8E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c01190 95da42973905784b38af63858e89bbf6 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.1E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSC_c01190 95da42973905784b38af63858e89bbf6 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.1E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSC_c01190 95da42973905784b38af63858e89bbf6 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.1E-9 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSC_c01190 95da42973905784b38af63858e89bbf6 285 Pfam PF03466 LysR substrate binding domain 83 282 7.4E-30 T 12-10-2018 IPR005119 LysR, substrate-binding TSC_c01190 95da42973905784b38af63858e89bbf6 285 Gene3D G3DSA:3.40.190.10 156 259 6.2E-41 T 12-10-2018 TSC_c01190 95da42973905784b38af63858e89bbf6 285 SUPERFAMILY SSF46785 1 100 4.18E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c01190 95da42973905784b38af63858e89bbf6 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 60 1.1E-21 T 12-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 TSC_c01190 95da42973905784b38af63858e89bbf6 285 SUPERFAMILY SSF53850 88 282 6.29E-26 T 12-10-2018 TSC_c12360 7df7be578636c51f95e310332dc63e0c 225 Pfam PF13612 Transposase DDE domain 111 199 5.6E-8 T 12-10-2018 IPR025668 Transposase DDE domain TSC_c04530 33c5a8b079c14214730d022463121374 224 SMART SM00448 2 114 6.6E-37 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c04530 33c5a8b079c14214730d022463121374 224 SUPERFAMILY SSF52172 1 174 3.11E-39 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c04530 33c5a8b079c14214730d022463121374 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 221 8.2E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c04530 33c5a8b079c14214730d022463121374 224 Gene3D G3DSA:1.10.10.10 124 224 1.3E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c04530 33c5a8b079c14214730d022463121374 224 Gene3D G3DSA:3.40.50.2300 1 123 1.1E-34 T 12-10-2018 TSC_c04530 33c5a8b079c14214730d022463121374 224 Pfam PF00072 Response regulator receiver domain 4 115 4.9E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c04530 33c5a8b079c14214730d022463121374 224 SMART SM00862 145 221 8.8E-27 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c02580 e34989906506cbdff5a3849bc5df73bb 420 Gene3D G3DSA:1.20.1600.10 20 414 5.5E-59 T 12-10-2018 TSC_c02580 e34989906506cbdff5a3849bc5df73bb 420 SUPERFAMILY SSF56954 6 413 8.37E-54 T 12-10-2018 TSC_c02580 e34989906506cbdff5a3849bc5df73bb 420 Pfam PF02321 Outer membrane efflux protein 23 194 5.3E-19 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSC_c02580 e34989906506cbdff5a3849bc5df73bb 420 Pfam PF02321 Outer membrane efflux protein 216 412 7.7E-25 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSC_c03710 ce13e396b097a5d5357a07e8391e5040 138 Pfam PF01592 NifU-like N terminal domain 8 115 5.5E-26 T 12-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 TSC_c03710 ce13e396b097a5d5357a07e8391e5040 138 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 4 137 1.4E-51 T 12-10-2018 TSC_c03710 ce13e396b097a5d5357a07e8391e5040 138 Gene3D G3DSA:3.90.1010.10 1 138 1.5E-60 T 12-10-2018 TSC_c03710 ce13e396b097a5d5357a07e8391e5040 138 SUPERFAMILY SSF82649 3 137 4.45E-51 T 12-10-2018 TSC_c01930 04506b386ff61f68cfcd389eb37a38e4 346 SUPERFAMILY SSF55347 150 314 1.57E-38 T 12-10-2018 TSC_c01930 04506b386ff61f68cfcd389eb37a38e4 346 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 6 340 38.144 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSC_c01930 04506b386ff61f68cfcd389eb37a38e4 346 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 145 161 - T 12-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSC_c01930 04506b386ff61f68cfcd389eb37a38e4 346 Hamap MF_02083 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase [lysY]. 6 346 50.374 T 12-10-2018 IPR037535 [LysW]-L-2-aminoadipate/[LysW]-L-glutamate phosphate reductase GO:0016620 TSC_c01930 04506b386ff61f68cfcd389eb37a38e4 346 SUPERFAMILY SSF51735 5 170 6.43E-37 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c01930 04506b386ff61f68cfcd389eb37a38e4 346 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 9 142 2.4E-26 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSC_c01930 04506b386ff61f68cfcd389eb37a38e4 346 Gene3D G3DSA:3.40.50.720 9 332 6.8E-113 T 12-10-2018 TSC_c01930 04506b386ff61f68cfcd389eb37a38e4 346 Gene3D G3DSA:3.30.360.10 148 318 6.8E-113 T 12-10-2018 TSC_c01930 04506b386ff61f68cfcd389eb37a38e4 346 SMART SM00859 7 142 6.2E-45 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSC_c01930 04506b386ff61f68cfcd389eb37a38e4 346 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 8 346 2.3E-111 T 12-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSC_c01930 04506b386ff61f68cfcd389eb37a38e4 346 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 169 317 1.8E-7 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSC_c07770 9c74a7bfa13693931690c676782939f9 101 Gene3D G3DSA:3.30.460.10 1 96 1.0E-26 T 12-10-2018 TSC_c07770 9c74a7bfa13693931690c676782939f9 101 Pfam PF01909 Nucleotidyltransferase domain 13 95 6.1E-15 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSC_c07770 9c74a7bfa13693931690c676782939f9 101 SUPERFAMILY SSF81301 10 99 2.84E-24 T 12-10-2018 TSC_c07330 24191ceefb9ae69d29cd2ef8f6ae5bb2 415 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 281 288 - T 12-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSC_c07330 24191ceefb9ae69d29cd2ef8f6ae5bb2 415 SUPERFAMILY SSF56059 101 312 4.95E-56 T 12-10-2018 TSC_c07330 24191ceefb9ae69d29cd2ef8f6ae5bb2 415 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 99 2.8E-34 T 12-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSC_c07330 24191ceefb9ae69d29cd2ef8f6ae5bb2 415 Gene3D G3DSA:3.30.1490.20 118 183 1.8E-19 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSC_c07330 24191ceefb9ae69d29cd2ef8f6ae5bb2 415 SMART SM01210 321 412 8.6E-48 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSC_c07330 24191ceefb9ae69d29cd2ef8f6ae5bb2 415 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 323 410 5.8E-27 T 12-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSC_c07330 24191ceefb9ae69d29cd2ef8f6ae5bb2 415 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 412 41.583 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSC_c07330 24191ceefb9ae69d29cd2ef8f6ae5bb2 415 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 100 287 1.0E-68 T 12-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSC_c07330 24191ceefb9ae69d29cd2ef8f6ae5bb2 415 Gene3D G3DSA:3.90.600.10 321 413 4.6E-34 T 12-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSC_c07330 24191ceefb9ae69d29cd2ef8f6ae5bb2 415 SMART SM01209 100 287 5.0E-111 T 12-10-2018 TSC_c07330 24191ceefb9ae69d29cd2ef8f6ae5bb2 415 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 412 9.1E-151 T 12-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSC_c07330 24191ceefb9ae69d29cd2ef8f6ae5bb2 415 SUPERFAMILY SSF51246 320 412 5.89E-29 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TSC_c07330 24191ceefb9ae69d29cd2ef8f6ae5bb2 415 Gene3D G3DSA:3.30.470.20 184 320 1.9E-56 T 12-10-2018 TSC_c07330 24191ceefb9ae69d29cd2ef8f6ae5bb2 415 SUPERFAMILY SSF52440 1 100 6.62E-33 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSC_c07330 24191ceefb9ae69d29cd2ef8f6ae5bb2 415 Gene3D G3DSA:3.40.50.20 1 92 1.7E-36 T 12-10-2018 TSC_c08870 d3506eb8903d0b2acad345bfd33b0d31 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 1.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSC_c08870 d3506eb8903d0b2acad345bfd33b0d31 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 1.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSC_c08870 d3506eb8903d0b2acad345bfd33b0d31 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSC_c08870 d3506eb8903d0b2acad345bfd33b0d31 144 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 1.0E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSC_c08870 d3506eb8903d0b2acad345bfd33b0d31 144 Pfam PF13463 Winged helix DNA-binding domain 39 101 1.1E-10 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSC_c08870 d3506eb8903d0b2acad345bfd33b0d31 144 ProSitePatterns PS01117 MarR-type HTH domain signature. 67 101 - T 12-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site TSC_c08870 d3506eb8903d0b2acad345bfd33b0d31 144 SUPERFAMILY SSF46785 7 140 1.49E-28 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c08870 d3506eb8903d0b2acad345bfd33b0d31 144 Gene3D G3DSA:1.10.10.10 3 141 9.8E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c08870 d3506eb8903d0b2acad345bfd33b0d31 144 SMART SM00347 29 128 9.8E-19 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 Hamap MF_00054_B Elongation factor G [fusA]. 8 691 114.055 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 TIGRFAM TIGR00484 EF-G: translation elongation factor G 6 689 0.0 T 12-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 Pfam PF00679 Elongation factor G C-terminus 600 686 3.0E-34 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 Pfam PF03144 Elongation factor Tu domain 2 323 389 1.4E-15 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 SUPERFAMILY SSF52540 7 282 1.27E-110 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 SUPERFAMILY SSF54980 402 480 3.6E-26 T 12-10-2018 IPR035647 EF-G domain III/V-like TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 SUPERFAMILY SSF50447 265 395 3.3E-36 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 SUPERFAMILY SSF54211 479 599 2.12E-49 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 Pfam PF14492 Elongation Factor G, domain II 404 478 2.3E-36 T 12-10-2018 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 Gene3D G3DSA:2.40.30.10 294 405 1.4E-42 T 12-10-2018 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 SMART SM00889 480 598 4.5E-78 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 Pfam PF03764 Elongation factor G, domain IV 479 597 5.8E-51 T 12-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 PRINTS PR00315 GTP-binding elongation factor signature 132 141 4.5E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 PRINTS PR00315 GTP-binding elongation factor signature 14 27 4.5E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 PRINTS PR00315 GTP-binding elongation factor signature 96 107 4.5E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 PRINTS PR00315 GTP-binding elongation factor signature 60 68 4.5E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 PRINTS PR00315 GTP-binding elongation factor signature 80 90 4.5E-16 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 SMART SM00838 600 687 1.3E-60 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 Pfam PF00009 Elongation factor Tu GTP binding domain 10 282 1.9E-68 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 SUPERFAMILY SSF54980 603 689 4.41E-34 T 12-10-2018 IPR035647 EF-G domain III/V-like TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 Gene3D G3DSA:3.40.50.300 4 293 1.2E-111 T 12-10-2018 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 Gene3D G3DSA:3.30.70.870 406 483 2.4E-34 T 12-10-2018 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 181 8.9E-33 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 Gene3D G3DSA:3.30.70.240 604 674 4.4E-99 T 12-10-2018 TSC_c22470 f29514b9f9a9c2615d8cb8bd81a43de2 691 Gene3D G3DSA:3.30.230.10 484 687 4.4E-99 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSC_c01080 8c145f648f0d1cc3528f1f2cfefa4be9 289 SUPERFAMILY SSF161098 37 281 2.71E-31 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c01080 8c145f648f0d1cc3528f1f2cfefa4be9 289 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 24 287 2.1E-76 T 12-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 TSC_c01080 8c145f648f0d1cc3528f1f2cfefa4be9 289 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 287 7.5E-21 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c01080 8c145f648f0d1cc3528f1f2cfefa4be9 289 Gene3D G3DSA:1.10.3720.10 70 288 1.8E-28 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c24320 627dc892e1980646a4029751aa674aea 304 SUPERFAMILY SSF50486 203 303 1.38E-30 T 12-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 TSC_c24320 627dc892e1980646a4029751aa674aea 304 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 295 2.3E-72 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 TSC_c24320 627dc892e1980646a4029751aa674aea 304 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 298 32.885 T 12-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 TSC_c24320 627dc892e1980646a4029751aa674aea 304 Pfam PF02911 Formyl transferase, C-terminal domain 202 295 5.3E-30 T 12-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TSC_c24320 627dc892e1980646a4029751aa674aea 304 SUPERFAMILY SSF53328 1 195 1.7E-54 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TSC_c24320 627dc892e1980646a4029751aa674aea 304 Pfam PF00551 Formyl transferase 1 177 2.7E-43 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TSC_c24320 627dc892e1980646a4029751aa674aea 304 Gene3D G3DSA:3.40.50.170 1 201 2.4E-64 T 12-10-2018 TSC_c24320 627dc892e1980646a4029751aa674aea 304 Gene3D G3DSA:3.10.25.10 203 304 8.4E-28 T 12-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TSC_c02940 f9960e1d8d7825bf39e08cf323b4c990 370 Gene3D G3DSA:3.40.50.2000 171 355 4.1E-63 T 12-10-2018 TSC_c02940 f9960e1d8d7825bf39e08cf323b4c990 370 SUPERFAMILY SSF53756 2 368 2.32E-74 T 12-10-2018 TSC_c02940 f9960e1d8d7825bf39e08cf323b4c990 370 Pfam PF00534 Glycosyl transferases group 1 193 349 8.1E-33 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TSC_c02940 f9960e1d8d7825bf39e08cf323b4c990 370 Gene3D G3DSA:3.40.50.2000 13 364 4.1E-63 T 12-10-2018 TSC_c02940 f9960e1d8d7825bf39e08cf323b4c990 370 Pfam PF13439 Glycosyltransferase Family 4 13 171 4.2E-22 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSC_c04360 30a0a39efbfda9a7cf3523ebd498ed72 111 Pfam PF13586 Transposase DDE domain 53 104 1.2E-9 T 12-10-2018 IPR025668 Transposase DDE domain TSC_c05110 d406b9361e4afd9c00156828b1306049 552 ProSitePatterns PS00785 5'-nucleotidase signature 1. 30 42 - T 12-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c05110 d406b9361e4afd9c00156828b1306049 552 SUPERFAMILY SSF55816 330 532 4.32E-71 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c05110 d406b9361e4afd9c00156828b1306049 552 PRINTS PR01607 Apyrase family signature 28 46 1.2E-40 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c05110 d406b9361e4afd9c00156828b1306049 552 PRINTS PR01607 Apyrase family signature 467 486 1.2E-40 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c05110 d406b9361e4afd9c00156828b1306049 552 PRINTS PR01607 Apyrase family signature 205 222 1.2E-40 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c05110 d406b9361e4afd9c00156828b1306049 552 PRINTS PR01607 Apyrase family signature 224 247 1.2E-40 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c05110 d406b9361e4afd9c00156828b1306049 552 PRINTS PR01607 Apyrase family signature 390 413 1.2E-40 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c05110 d406b9361e4afd9c00156828b1306049 552 PRINTS PR01607 Apyrase family signature 269 289 1.2E-40 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c05110 d406b9361e4afd9c00156828b1306049 552 Gene3D G3DSA:3.90.780.10 333 534 1.9E-90 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c05110 d406b9361e4afd9c00156828b1306049 552 SUPERFAMILY SSF56300 28 318 1.22E-88 T 12-10-2018 TSC_c05110 d406b9361e4afd9c00156828b1306049 552 Pfam PF00149 Calcineurin-like phosphoesterase 31 241 6.7E-12 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSC_c05110 d406b9361e4afd9c00156828b1306049 552 ProSitePatterns PS00786 5'-nucleotidase signature 2. 108 119 - T 12-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c05110 d406b9361e4afd9c00156828b1306049 552 Gene3D G3DSA:3.60.21.10 28 332 7.0E-125 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TSC_c05110 d406b9361e4afd9c00156828b1306049 552 Pfam PF02872 5'-nucleotidase, C-terminal domain 333 494 1.0E-52 T 12-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c20120 d74ce188478460a3222cb8f2d7275439 325 SUPERFAMILY SSF64182 27 320 4.58E-53 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily TSC_c20120 d74ce188478460a3222cb8f2d7275439 325 Gene3D G3DSA:3.90.1640.10 12 200 4.6E-48 T 12-10-2018 TSC_c20120 d74ce188478460a3222cb8f2d7275439 325 Pfam PF02272 DHHA1 domain 253 315 1.0E-10 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TSC_c20120 d74ce188478460a3222cb8f2d7275439 325 Pfam PF01368 DHH family 28 162 3.7E-10 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TSC_c20120 d74ce188478460a3222cb8f2d7275439 325 Gene3D G3DSA:3.10.310.30 204 321 2.0E-19 T 12-10-2018 TSC_c10230 1e76de804b4658c9ce17738a9f332809 432 Pfam PF00202 Aminotransferase class-III 34 428 2.2E-114 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c10230 1e76de804b4658c9ce17738a9f332809 432 Gene3D G3DSA:3.40.640.10 69 331 9.2E-151 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c10230 1e76de804b4658c9ce17738a9f332809 432 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 251 288 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c10230 1e76de804b4658c9ce17738a9f332809 432 SUPERFAMILY SSF53383 27 430 3.31E-127 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c10230 1e76de804b4658c9ce17738a9f332809 432 Gene3D G3DSA:3.90.1150.10 13 426 9.2E-151 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c10230 1e76de804b4658c9ce17738a9f332809 432 PIRSF PIRSF000521 130 432 2.6E-43 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c10230 1e76de804b4658c9ce17738a9f332809 432 PIRSF PIRSF000521 1 134 3.0E-8 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c04700 7de786adfd2b8b5d2bbcce05cc3bc1f2 391 SUPERFAMILY SSF56349 69 372 2.27E-66 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSC_c04700 7de786adfd2b8b5d2bbcce05cc3bc1f2 391 Pfam PF00589 Phage integrase family 186 367 1.3E-28 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSC_c04700 7de786adfd2b8b5d2bbcce05cc3bc1f2 391 Gene3D G3DSA:1.10.150.130 69 175 1.7E-13 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal TSC_c04700 7de786adfd2b8b5d2bbcce05cc3bc1f2 391 Gene3D G3DSA:1.10.443.10 176 379 5.8E-52 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSC_c15420 064dc42f31ed74b1849e45c08d9ae5fe 297 Gene3D G3DSA:3.10.310.10 127 288 2.3E-39 T 12-10-2018 TSC_c15420 064dc42f31ed74b1849e45c08d9ae5fe 297 Pfam PF02567 Phenazine biosynthesis-like protein 9 295 2.8E-56 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 TSC_c15420 064dc42f31ed74b1849e45c08d9ae5fe 297 PIRSF PIRSF016184 1 297 3.7E-64 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 TSC_c15420 064dc42f31ed74b1849e45c08d9ae5fe 297 Gene3D G3DSA:3.10.310.10 2 125 4.6E-27 T 12-10-2018 TSC_c15420 064dc42f31ed74b1849e45c08d9ae5fe 297 SUPERFAMILY SSF54506 3 296 5.01E-55 T 12-10-2018 TSC_c15420 064dc42f31ed74b1849e45c08d9ae5fe 297 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 5 296 5.9E-49 T 12-10-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 TSC_c05340 53148956250497dc4403f4a5f5d38c40 132 Pfam PF03061 Thioesterase superfamily 47 117 9.9E-18 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TSC_c05340 53148956250497dc4403f4a5f5d38c40 132 Gene3D G3DSA:3.10.129.10 4 132 1.4E-35 T 12-10-2018 TSC_c05340 53148956250497dc4403f4a5f5d38c40 132 SUPERFAMILY SSF54637 4 129 3.25E-32 T 12-10-2018 IPR029069 HotDog domain superfamily TSC_c05340 53148956250497dc4403f4a5f5d38c40 132 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 16 130 3.0E-22 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 TSC_c22630 924d40ca414f6c93a6c9b5e6efe39043 329 SUPERFAMILY SSF52418 70 325 2.22E-81 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c22630 924d40ca414f6c93a6c9b5e6efe39043 329 Pfam PF02885 Glycosyl transferase family, helical bundle domain 3 63 1.5E-17 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c22630 924d40ca414f6c93a6c9b5e6efe39043 329 Pfam PF00591 Glycosyl transferase family, a/b domain 72 317 7.5E-83 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c22630 924d40ca414f6c93a6c9b5e6efe39043 329 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 2 326 35.302 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 TSC_c22630 924d40ca414f6c93a6c9b5e6efe39043 329 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 6 325 4.5E-111 T 12-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 TSC_c22630 924d40ca414f6c93a6c9b5e6efe39043 329 Gene3D G3DSA:3.40.1030.10 68 328 1.0E-99 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c22630 924d40ca414f6c93a6c9b5e6efe39043 329 Gene3D G3DSA:1.20.970.10 1 66 7.6E-22 T 12-10-2018 TSC_c22630 924d40ca414f6c93a6c9b5e6efe39043 329 SUPERFAMILY SSF47648 3 67 3.01E-17 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c03300 cb37a08fa5b7276c1adaddeb812f2170 349 SUPERFAMILY SSF46565 1 90 3.01E-33 T 12-10-2018 IPR036869 Chaperone J-domain superfamily TSC_c03300 cb37a08fa5b7276c1adaddeb812f2170 349 PRINTS PR00625 DnaJ domain signature 5 23 1.3E-24 T 12-10-2018 IPR001623 DnaJ domain TSC_c03300 cb37a08fa5b7276c1adaddeb812f2170 349 PRINTS PR00625 DnaJ domain signature 40 60 1.3E-24 T 12-10-2018 IPR001623 DnaJ domain TSC_c03300 cb37a08fa5b7276c1adaddeb812f2170 349 PRINTS PR00625 DnaJ domain signature 23 38 1.3E-24 T 12-10-2018 IPR001623 DnaJ domain TSC_c03300 cb37a08fa5b7276c1adaddeb812f2170 349 Gene3D G3DSA:2.60.260.20 233 337 9.3E-24 T 12-10-2018 TSC_c03300 cb37a08fa5b7276c1adaddeb812f2170 349 SUPERFAMILY SSF49493 238 323 1.57E-18 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TSC_c03300 cb37a08fa5b7276c1adaddeb812f2170 349 Pfam PF00684 DnaJ central domain 128 188 4.6E-11 T 12-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 TSC_c03300 cb37a08fa5b7276c1adaddeb812f2170 349 Pfam PF01556 DnaJ C terminal domain 101 312 1.1E-31 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal TSC_c03300 cb37a08fa5b7276c1adaddeb812f2170 349 Gene3D G3DSA:2.10.230.10 128 188 2.0E-31 T 12-10-2018 TSC_c03300 cb37a08fa5b7276c1adaddeb812f2170 349 SMART SM00271 2 60 2.4E-36 T 12-10-2018 IPR001623 DnaJ domain TSC_c03300 cb37a08fa5b7276c1adaddeb812f2170 349 Gene3D G3DSA:1.10.287.110 1 97 1.7E-34 T 12-10-2018 IPR036869 Chaperone J-domain superfamily TSC_c03300 cb37a08fa5b7276c1adaddeb812f2170 349 Gene3D G3DSA:2.60.260.20 98 228 2.0E-31 T 12-10-2018 TSC_c03300 cb37a08fa5b7276c1adaddeb812f2170 349 SUPERFAMILY SSF57938 115 191 3.01E-14 T 12-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily TSC_c03300 cb37a08fa5b7276c1adaddeb812f2170 349 ProSitePatterns PS00636 Nt-dnaJ domain signature. 45 64 - T 12-10-2018 IPR018253 DnaJ domain, conserved site TSC_c03300 cb37a08fa5b7276c1adaddeb812f2170 349 SUPERFAMILY SSF49493 96 241 6.8E-17 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TSC_c03300 cb37a08fa5b7276c1adaddeb812f2170 349 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 346 35.131 T 12-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 TSC_c03300 cb37a08fa5b7276c1adaddeb812f2170 349 Pfam PF00226 DnaJ domain 3 65 1.5E-31 T 12-10-2018 IPR001623 DnaJ domain TSC_c15620 a58f39ab300f35c536a8a88bb7f9ba42 165 SUPERFAMILY SSF50685 71 153 1.78E-14 T 12-10-2018 IPR036908 RlpA-like domain superfamily TSC_c15620 a58f39ab300f35c536a8a88bb7f9ba42 165 Gene3D G3DSA:2.40.40.10 71 163 5.9E-37 T 12-10-2018 IPR036908 RlpA-like domain superfamily TSC_c15620 a58f39ab300f35c536a8a88bb7f9ba42 165 Pfam PF01476 LysM domain 18 59 2.1E-16 T 12-10-2018 IPR018392 LysM domain TSC_c15620 a58f39ab300f35c536a8a88bb7f9ba42 165 SUPERFAMILY SSF54106 16 59 1.1E-12 T 12-10-2018 TSC_c15620 a58f39ab300f35c536a8a88bb7f9ba42 165 Gene3D G3DSA:3.10.350.10 15 60 8.0E-20 T 12-10-2018 IPR036779 LysM domain superfamily TSC_c15620 a58f39ab300f35c536a8a88bb7f9ba42 165 SMART SM00257 17 60 3.3E-17 T 12-10-2018 IPR018392 LysM domain TSC_c15620 a58f39ab300f35c536a8a88bb7f9ba42 165 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 74 163 3.9E-41 T 12-10-2018 IPR012997 Rare lipoprotein A TSC_c15620 a58f39ab300f35c536a8a88bb7f9ba42 165 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 11 162 23.385 T 12-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 TSC_c15620 a58f39ab300f35c536a8a88bb7f9ba42 165 Pfam PF03330 Lytic transglycolase 73 160 7.7E-25 T 12-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain TSC_c07020 459ec4a4f5043ff277a5ce9fc3abea6c 198 Pfam PF13563 2'-5' RNA ligase superfamily 36 180 2.7E-20 T 12-10-2018 TSC_c07020 459ec4a4f5043ff277a5ce9fc3abea6c 198 Gene3D G3DSA:3.90.1140.10 29 194 5.4E-27 T 12-10-2018 TSC_c07020 459ec4a4f5043ff277a5ce9fc3abea6c 198 SUPERFAMILY SSF55144 29 191 1.86E-24 T 12-10-2018 IPR009097 Cyclic phosphodiesterase TSC_c13130 e5a1a9032268c05b229c938e827403ae 420 Gene3D G3DSA:3.40.1830.10 13 189 1.5E-61 T 12-10-2018 IPR035097 Peptidase M29, N-terminal TSC_c13130 e5a1a9032268c05b229c938e827403ae 420 SUPERFAMILY SSF144052 16 420 3.66E-136 T 12-10-2018 TSC_c13130 e5a1a9032268c05b229c938e827403ae 420 Pfam PF02073 Thermophilic metalloprotease (M29) 16 418 1.3E-154 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TSC_c13130 e5a1a9032268c05b229c938e827403ae 420 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 313 333 2.2E-90 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TSC_c13130 e5a1a9032268c05b229c938e827403ae 420 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 399 418 2.2E-90 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TSC_c13130 e5a1a9032268c05b229c938e827403ae 420 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 257 276 2.2E-90 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TSC_c13130 e5a1a9032268c05b229c938e827403ae 420 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 336 357 2.2E-90 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TSC_c13130 e5a1a9032268c05b229c938e827403ae 420 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 168 190 2.2E-90 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TSC_c13130 e5a1a9032268c05b229c938e827403ae 420 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 27 44 2.2E-90 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TSC_c13130 e5a1a9032268c05b229c938e827403ae 420 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 92 111 2.2E-90 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TSC_c13130 e5a1a9032268c05b229c938e827403ae 420 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 373 395 2.2E-90 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TSC_c13480 763c453539b583b898590b400d348316 331 Gene3D G3DSA:3.40.50.920 198 331 1.7E-45 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSC_c13480 763c453539b583b898590b400d348316 331 SMART SM00861 9 184 4.2E-63 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSC_c13480 763c453539b583b898590b400d348316 331 Gene3D G3DSA:3.40.50.970 7 197 1.4E-80 T 12-10-2018 TSC_c13480 763c453539b583b898590b400d348316 331 SUPERFAMILY SSF52518 7 208 1.5E-67 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c13480 763c453539b583b898590b400d348316 331 Pfam PF02779 Transketolase, pyrimidine binding domain 10 183 1.8E-42 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSC_c13480 763c453539b583b898590b400d348316 331 SUPERFAMILY SSF52922 194 330 5.23E-38 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSC_c13480 763c453539b583b898590b400d348316 331 Pfam PF02780 Transketolase, C-terminal domain 199 321 2.8E-37 T 12-10-2018 IPR033248 Transketolase, C-terminal domain TSC_c04870 6d6afeddd5df01346f76f2de1dfb6af1 215 Pfam PF04367 Protein of unknown function (DUF502) 64 164 3.0E-24 T 12-10-2018 IPR007462 Protein of unknown function DUF502 TSC_c23460 ec99f66f2f10370c8aa6528b9501c196 150 Gene3D G3DSA:3.40.50.2300 1 129 8.2E-34 T 12-10-2018 TSC_c23460 ec99f66f2f10370c8aa6528b9501c196 150 SMART SM00226 1 132 2.3E-25 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TSC_c23460 ec99f66f2f10370c8aa6528b9501c196 150 SUPERFAMILY SSF52788 1 130 3.53E-32 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily TSC_c23460 ec99f66f2f10370c8aa6528b9501c196 150 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 129 4.6E-16 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TSC_c24070 f17fc47b9f6d5129f49f4589d77d2561 268 Pfam PF00005 ABC transporter 37 193 3.1E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c24070 f17fc47b9f6d5129f49f4589d77d2561 268 Gene3D G3DSA:3.40.50.300 18 267 3.2E-66 T 12-10-2018 TSC_c24070 f17fc47b9f6d5129f49f4589d77d2561 268 ProSitePatterns PS00211 ABC transporters family signature. 165 179 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c24070 f17fc47b9f6d5129f49f4589d77d2561 268 SMART SM00382 46 242 7.3E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c24070 f17fc47b9f6d5129f49f4589d77d2561 268 SUPERFAMILY SSF52540 20 252 3.42E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c24070 f17fc47b9f6d5129f49f4589d77d2561 268 TIGRFAM TIGR02315 ABC_phnC: phosphonate ABC transporter, ATP-binding protein 20 261 9.4E-98 T 12-10-2018 IPR012693 ABC transporter, phosphonate import, PhnC GO:0005524|GO:0015416|GO:0015716|GO:0016020 TSC_c00570 6d9858125b6c38e4610ed08ad5ce5faf 137 Pfam PF04314 Copper chaperone PCu(A)C 21 130 4.1E-31 T 12-10-2018 IPR007410 Copper chaperone PCuAC TSC_c00570 6d9858125b6c38e4610ed08ad5ce5faf 137 SUPERFAMILY SSF110087 4 135 2.22E-36 T 12-10-2018 IPR036182 Copper chaperone PCuAC superfamily TSC_c00570 6d9858125b6c38e4610ed08ad5ce5faf 137 Gene3D G3DSA:2.60.40.1890 21 137 3.8E-37 T 12-10-2018 IPR036182 Copper chaperone PCuAC superfamily TSC_c17320 5135fc046bb342b49486b2650844d65b 421 SMART SM00382 32 228 3.5E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c17320 5135fc046bb342b49486b2650844d65b 421 Pfam PF00005 ABC transporter 23 162 6.7E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c17320 5135fc046bb342b49486b2650844d65b 421 Pfam PF09821 C-terminal AAA-associated domain 291 405 3.6E-32 T 12-10-2018 IPR018632 C-terminal AAA-associated domain TSC_c17320 5135fc046bb342b49486b2650844d65b 421 Gene3D G3DSA:3.40.50.300 1 261 2.0E-65 T 12-10-2018 TSC_c17320 5135fc046bb342b49486b2650844d65b 421 SUPERFAMILY SSF52540 4 244 8.31E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c17320 5135fc046bb342b49486b2650844d65b 421 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c06000 4c0bd173ca1e2ee6680772ee8ae8134f 437 Gene3D G3DSA:1.20.1440.230 335 437 3.1E-35 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06000 4c0bd173ca1e2ee6680772ee8ae8134f 437 SUPERFAMILY SSF140490 334 430 6.67E-32 T 12-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06000 4c0bd173ca1e2ee6680772ee8ae8134f 437 Gene3D G3DSA:3.40.50.11540 62 239 1.7E-85 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06000 4c0bd173ca1e2ee6680772ee8ae8134f 437 SUPERFAMILY SSF142019 16 247 1.57E-92 T 12-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06000 4c0bd173ca1e2ee6680772ee8ae8134f 437 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 18 422 1.6E-174 T 12-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06000 4c0bd173ca1e2ee6680772ee8ae8134f 437 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 175 190 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06000 4c0bd173ca1e2ee6680772ee8ae8134f 437 Gene3D G3DSA:3.10.20.600 240 334 1.3E-36 T 12-10-2018 TSC_c06000 4c0bd173ca1e2ee6680772ee8ae8134f 437 SUPERFAMILY SSF142984 249 331 2.75E-24 T 12-10-2018 TSC_c06000 4c0bd173ca1e2ee6680772ee8ae8134f 437 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 350 361 - T 12-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06000 4c0bd173ca1e2ee6680772ee8ae8134f 437 Pfam PF10531 SLBB domain 251 297 2.6E-12 T 12-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06000 4c0bd173ca1e2ee6680772ee8ae8134f 437 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 339 421 4.0E-25 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06000 4c0bd173ca1e2ee6680772ee8ae8134f 437 SMART SM00928 337 383 1.7E-19 T 12-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06000 4c0bd173ca1e2ee6680772ee8ae8134f 437 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 57 226 1.8E-52 T 12-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c12490 76e94f2f30bbae41e887ac85408a3444 171 TIGRFAM TIGR02548 casB_cse2: CRISPR type I-E/ECOLI-associated protein CasB/Cse2 6 156 2.7E-36 T 12-10-2018 IPR013382 CRISPR-associated protein Cse2 TSC_c12490 76e94f2f30bbae41e887ac85408a3444 171 Gene3D G3DSA:1.10.520.40 1 157 2.1E-59 T 12-10-2018 IPR038287 Cse2 superfamily TSC_c12490 76e94f2f30bbae41e887ac85408a3444 171 Pfam PF09485 CRISPR-associated protein Cse2 (CRISPR_cse2) 22 155 1.8E-31 T 12-10-2018 IPR013382 CRISPR-associated protein Cse2 TSC_c16960 8012d3340dfc95380ab2a9a03942da63 196 ProSitePatterns PS01126 Elongation factor Ts signature 1. 10 25 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSC_c16960 8012d3340dfc95380ab2a9a03942da63 196 Gene3D G3DSA:1.10.8.10 1 54 2.1E-23 T 12-10-2018 TSC_c16960 8012d3340dfc95380ab2a9a03942da63 196 Hamap MF_00050 Elongation factor Ts [tsf]. 1 196 43.706 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSC_c16960 8012d3340dfc95380ab2a9a03942da63 196 SUPERFAMILY SSF46934 4 53 2.96E-15 T 12-10-2018 IPR009060 UBA-like superfamily GO:0005515 TSC_c16960 8012d3340dfc95380ab2a9a03942da63 196 ProSitePatterns PS01127 Elongation factor Ts signature 2. 75 85 - T 12-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSC_c16960 8012d3340dfc95380ab2a9a03942da63 196 Gene3D G3DSA:1.10.286.20 110 154 6.7E-62 T 12-10-2018 TSC_c16960 8012d3340dfc95380ab2a9a03942da63 196 Pfam PF00889 Elongation factor TS 33 195 9.7E-41 T 12-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 TSC_c16960 8012d3340dfc95380ab2a9a03942da63 196 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 3 93 5.9E-32 T 12-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 TSC_c16960 8012d3340dfc95380ab2a9a03942da63 196 SUPERFAMILY SSF54713 55 195 1.09E-54 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 TSC_c16960 8012d3340dfc95380ab2a9a03942da63 196 Gene3D G3DSA:3.30.479.20 58 195 6.7E-62 T 12-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 TSC_c13680 510bbd0a5236646fb468883f90aa57ef 1010 Gene3D G3DSA:3.40.50.300 5 309 4.7E-34 T 12-10-2018 TSC_c13680 510bbd0a5236646fb468883f90aa57ef 1010 Pfam PF02463 RecF/RecN/SMC N terminal domain 7 995 4.8E-41 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal TSC_c13680 510bbd0a5236646fb468883f90aa57ef 1010 SUPERFAMILY SSF75553 399 608 4.84E-34 T 12-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 TSC_c13680 510bbd0a5236646fb468883f90aa57ef 1010 SUPERFAMILY SSF52540 6 275 2.94E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c13680 510bbd0a5236646fb468883f90aa57ef 1010 Gene3D G3DSA:1.20.1060.20 442 599 3.9E-36 T 12-10-2018 TSC_c13680 510bbd0a5236646fb468883f90aa57ef 1010 SMART SM00968 445 561 3.9E-29 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 TSC_c13680 510bbd0a5236646fb468883f90aa57ef 1010 Pfam PF06470 SMC proteins Flexible Hinge Domain 445 560 1.6E-20 T 12-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 TSC_c13680 510bbd0a5236646fb468883f90aa57ef 1010 PIRSF PIRSF005719 322 647 2.2E-44 T 12-10-2018 IPR024704 Structural maintenance of chromosomes protein TSC_c13680 510bbd0a5236646fb468883f90aa57ef 1010 PIRSF PIRSF005719 5 307 1.2E-62 T 12-10-2018 IPR024704 Structural maintenance of chromosomes protein TSC_c13680 510bbd0a5236646fb468883f90aa57ef 1010 PIRSF PIRSF005719 661 1010 1.4E-49 T 12-10-2018 IPR024704 Structural maintenance of chromosomes protein TSC_c13680 510bbd0a5236646fb468883f90aa57ef 1010 Gene3D G3DSA:3.30.70.1620 504 589 3.9E-36 T 12-10-2018 TSC_c13680 510bbd0a5236646fb468883f90aa57ef 1010 SUPERFAMILY SSF52540 341 1000 7.93E-17 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c13680 510bbd0a5236646fb468883f90aa57ef 1010 Gene3D G3DSA:3.40.50.300 805 1007 1.8E-27 T 12-10-2018 TSC_c21420 739078de1ee4f5c030f36264bdf8573d 149 Pfam PF02643 Uncharacterized ACR, COG1430 54 148 4.0E-11 T 12-10-2018 IPR003795 Protein of unknown function DUF192 TSC_c21420 739078de1ee4f5c030f36264bdf8573d 149 Gene3D G3DSA:2.60.120.1140 28 148 4.1E-12 T 12-10-2018 IPR038695 Saro_0823-like superfamily TSC_c21900 25d966025d9ba3154bb94cca1ce68857 158 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 89 144 1.0E-20 T 12-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 TSC_c21900 25d966025d9ba3154bb94cca1ce68857 158 SUPERFAMILY SSF46785 2 67 1.77E-19 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c21900 25d966025d9ba3154bb94cca1ce68857 158 Gene3D G3DSA:1.10.10.10 5 67 4.8E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c21900 25d966025d9ba3154bb94cca1ce68857 158 TIGRFAM TIGR01529 argR_whole: arginine repressor 6 151 8.9E-50 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TSC_c21900 25d966025d9ba3154bb94cca1ce68857 158 Gene3D G3DSA:3.30.1360.40 72 151 4.9E-22 T 12-10-2018 TSC_c21900 25d966025d9ba3154bb94cca1ce68857 158 PRINTS PR01467 Bacterial arginine repressor signature 90 103 9.4E-22 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TSC_c21900 25d966025d9ba3154bb94cca1ce68857 158 PRINTS PR01467 Bacterial arginine repressor signature 38 53 9.4E-22 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TSC_c21900 25d966025d9ba3154bb94cca1ce68857 158 PRINTS PR01467 Bacterial arginine repressor signature 120 135 9.4E-22 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TSC_c21900 25d966025d9ba3154bb94cca1ce68857 158 PRINTS PR01467 Bacterial arginine repressor signature 22 35 9.4E-22 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TSC_c21900 25d966025d9ba3154bb94cca1ce68857 158 Pfam PF01316 Arginine repressor, DNA binding domain 3 67 1.5E-24 T 12-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 TSC_c21900 25d966025d9ba3154bb94cca1ce68857 158 SUPERFAMILY SSF55252 86 150 1.2E-15 T 12-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 TSC_c21900 25d966025d9ba3154bb94cca1ce68857 158 Pfam PF02863 Arginine repressor, C-terminal domain 85 147 3.6E-21 T 12-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 TSC_c21900 25d966025d9ba3154bb94cca1ce68857 158 Hamap MF_00173 Arginine repressor [argR]. 1 154 56.538 T 12-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 TSC_c17220 8f5b387637310419d30f806a93c10da7 348 SUPERFAMILY SSF51726 9 344 2.09E-108 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TSC_c17220 8f5b387637310419d30f806a93c10da7 348 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 10 343 6.3E-128 T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TSC_c17220 8f5b387637310419d30f806a93c10da7 348 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 143 159 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TSC_c17220 8f5b387637310419d30f806a93c10da7 348 Gene3D G3DSA:3.20.20.210 2 348 2.4E-141 T 12-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 TSC_c17220 8f5b387637310419d30f806a93c10da7 348 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 26 35 - T 12-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TSC_c17220 8f5b387637310419d30f806a93c10da7 348 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 13 342 5.6E-128 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TSC_c17220 8f5b387637310419d30f806a93c10da7 348 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 10 345 47.441 T 12-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 TSC_c01460 1535b9e823694e5fe284832eb7f6b722 143 SUPERFAMILY SSF54631 1 140 4.42E-36 T 12-10-2018 TSC_c01460 1535b9e823694e5fe284832eb7f6b722 143 Pfam PF00571 CBS domain 71 124 1.2E-17 T 12-10-2018 IPR000644 CBS domain TSC_c01460 1535b9e823694e5fe284832eb7f6b722 143 Pfam PF00571 CBS domain 14 60 1.0E-8 T 12-10-2018 IPR000644 CBS domain TSC_c01460 1535b9e823694e5fe284832eb7f6b722 143 SMART SM00116 78 125 3.2E-14 T 12-10-2018 IPR000644 CBS domain TSC_c01460 1535b9e823694e5fe284832eb7f6b722 143 SMART SM00116 13 60 1.2E-7 T 12-10-2018 IPR000644 CBS domain TSC_c01460 1535b9e823694e5fe284832eb7f6b722 143 Gene3D G3DSA:3.10.580.10 1 141 1.5E-47 T 12-10-2018 TSC_c06480 0d8c5af99c559cddfd96f4bdee71cc19 159 SMART SM00506 3 129 1.2E-36 T 12-10-2018 IPR002589 Macro domain TSC_c06480 0d8c5af99c559cddfd96f4bdee71cc19 159 Gene3D G3DSA:3.40.220.10 1 159 3.1E-61 T 12-10-2018 TSC_c06480 0d8c5af99c559cddfd96f4bdee71cc19 159 SUPERFAMILY SSF52949 3 158 3.03E-47 T 12-10-2018 TSC_c06480 0d8c5af99c559cddfd96f4bdee71cc19 159 Pfam PF01661 Macro domain 20 129 1.0E-32 T 12-10-2018 IPR002589 Macro domain TSC_c16170 d20417ea955a3782132968ea83292726 621 Gene3D G3DSA:1.10.10.160 96 173 1.1E-76 T 12-10-2018 IPR013986 DExx box DNA helicase domain superfamily TSC_c16170 d20417ea955a3782132968ea83292726 621 Gene3D G3DSA:1.10.486.10 365 507 1.0E-66 T 12-10-2018 TSC_c16170 d20417ea955a3782132968ea83292726 621 Gene3D G3DSA:3.40.50.300 2 257 1.1E-76 T 12-10-2018 TSC_c16170 d20417ea955a3782132968ea83292726 621 Pfam PF13361 UvrD-like helicase C-terminal domain 261 576 1.7E-47 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TSC_c16170 d20417ea955a3782132968ea83292726 621 SUPERFAMILY SSF52540 2 598 2.78E-129 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c16170 d20417ea955a3782132968ea83292726 621 Pfam PF13245 AAA domain 6 239 1.5E-36 T 12-10-2018 TSC_c16170 d20417ea955a3782132968ea83292726 621 Gene3D G3DSA:3.40.50.300 265 589 1.0E-66 T 12-10-2018 TSC_c11150 a3f492a6415ee24bee9f2e0514a9c5e1 172 Pfam PF04239 Protein of unknown function (DUF421) 96 157 2.1E-12 T 12-10-2018 IPR007353 Protein of unknown function DUF421 TSC_c11150 a3f492a6415ee24bee9f2e0514a9c5e1 172 Gene3D G3DSA:3.30.240.20 89 158 6.1E-18 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily TSC_c06910 931cf344678051bc31cadbb9b90c64d2 474 Gene3D G3DSA:3.40.640.10 84 311 1.7E-57 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c06910 931cf344678051bc31cadbb9b90c64d2 474 SUPERFAMILY SSF53383 3 470 3.52E-124 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c06910 931cf344678051bc31cadbb9b90c64d2 474 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 4 472 55.311 T 12-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 TSC_c06910 931cf344678051bc31cadbb9b90c64d2 474 Gene3D G3DSA:3.90.1150.10 332 457 1.0E-47 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c06910 931cf344678051bc31cadbb9b90c64d2 474 Pfam PF02347 Glycine cleavage system P-protein 88 293 5.4E-5 T 12-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 TSC_c22540 e0e7425c5dc4050406ab755a1dc4fd24 521 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 10 520 2.1E-162 T 12-10-2018 IPR019986 DAK2 domain-containing protein YloV TSC_c22540 e0e7425c5dc4050406ab755a1dc4fd24 521 Pfam PF02734 DAK2 domain 34 192 4.1E-39 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 TSC_c22540 e0e7425c5dc4050406ab755a1dc4fd24 521 Pfam PF13684 Dihydroxyacetone kinase family 219 517 1.7E-78 T 12-10-2018 IPR033470 Uncharacterised protein, DhaK domain TSC_c22540 e0e7425c5dc4050406ab755a1dc4fd24 521 SUPERFAMILY SSF101473 7 195 6.41E-41 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 TSC_c22540 e0e7425c5dc4050406ab755a1dc4fd24 521 Gene3D G3DSA:1.25.40.340 6 186 3.1E-8 T 12-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 TSC_c22540 e0e7425c5dc4050406ab755a1dc4fd24 521 SMART SM01120 34 194 2.1E-60 T 12-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 TSC_c22540 e0e7425c5dc4050406ab755a1dc4fd24 521 SMART SM01121 219 521 5.3E-123 T 12-10-2018 IPR033470 Uncharacterised protein, DhaK domain TSC_c19570 36e1d14d0d2f4e07a58faf47c2ef5bfa 351 Gene3D G3DSA:3.40.50.1100 60 156 1.4E-130 T 12-10-2018 TSC_c19570 36e1d14d0d2f4e07a58faf47c2ef5bfa 351 PIRSF PIRSF038945 2 350 1.1E-155 T 12-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 TSC_c19570 36e1d14d0d2f4e07a58faf47c2ef5bfa 351 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 52 65 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TSC_c19570 36e1d14d0d2f4e07a58faf47c2ef5bfa 351 TIGRFAM TIGR00260 thrC: threonine synthase 6 324 1.7E-90 T 12-10-2018 IPR004450 Threonine synthase-like TSC_c19570 36e1d14d0d2f4e07a58faf47c2ef5bfa 351 Gene3D G3DSA:3.40.50.1100 8 324 1.4E-130 T 12-10-2018 TSC_c19570 36e1d14d0d2f4e07a58faf47c2ef5bfa 351 SUPERFAMILY SSF53686 6 345 2.62E-98 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSC_c19570 36e1d14d0d2f4e07a58faf47c2ef5bfa 351 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 318 1.5E-70 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSC_c20800 f0b5bdcadc4a299fd9ea36f0c6c9b1a4 432 PIRSF PIRSF006485 1 432 3.6E-152 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 TSC_c20800 f0b5bdcadc4a299fd9ea36f0c6c9b1a4 432 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 154 3.3E-25 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSC_c20800 f0b5bdcadc4a299fd9ea36f0c6c9b1a4 432 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 173 334 1.0E-29 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSC_c20800 f0b5bdcadc4a299fd9ea36f0c6c9b1a4 432 Gene3D G3DSA:3.40.50.300 1 161 6.9E-47 T 12-10-2018 TSC_c20800 f0b5bdcadc4a299fd9ea36f0c6c9b1a4 432 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 346 426 4.3E-26 T 12-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like TSC_c20800 f0b5bdcadc4a299fd9ea36f0c6c9b1a4 432 Pfam PF01926 50S ribosome-binding GTPase 3 117 4.6E-27 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c20800 f0b5bdcadc4a299fd9ea36f0c6c9b1a4 432 Pfam PF01926 50S ribosome-binding GTPase 176 290 1.9E-26 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c20800 f0b5bdcadc4a299fd9ea36f0c6c9b1a4 432 SUPERFAMILY SSF52540 135 429 2.16E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c20800 f0b5bdcadc4a299fd9ea36f0c6c9b1a4 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 244 262 2.8E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c20800 f0b5bdcadc4a299fd9ea36f0c6c9b1a4 432 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 176 196 2.8E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c20800 f0b5bdcadc4a299fd9ea36f0c6c9b1a4 432 Gene3D G3DSA:3.40.50.300 171 341 1.9E-47 T 12-10-2018 TSC_c20800 f0b5bdcadc4a299fd9ea36f0c6c9b1a4 432 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 426 9.1E-148 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 TSC_c20800 f0b5bdcadc4a299fd9ea36f0c6c9b1a4 432 SUPERFAMILY SSF52540 3 161 1.22E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c20800 f0b5bdcadc4a299fd9ea36f0c6c9b1a4 432 Hamap MF_00195 GTPase Der [der]. 1 429 34.708 T 12-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 TSC_c20800 f0b5bdcadc4a299fd9ea36f0c6c9b1a4 432 Gene3D G3DSA:3.30.300.20 346 429 1.1E-24 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TSC_c00120 8ad13ed64b93d820cc9b1c349c61dda5 118 TIGRFAM TIGR00526 folB_dom: FolB domain 4 111 1.6E-20 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TSC_c00120 8ad13ed64b93d820cc9b1c349c61dda5 118 Pfam PF02152 Dihydroneopterin aldolase 4 112 1.5E-29 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TSC_c00120 8ad13ed64b93d820cc9b1c349c61dda5 118 SMART SM00905 4 115 3.1E-40 T 12-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TSC_c00120 8ad13ed64b93d820cc9b1c349c61dda5 118 Gene3D G3DSA:3.30.1130.10 1 118 2.1E-35 T 12-10-2018 TSC_c00120 8ad13ed64b93d820cc9b1c349c61dda5 118 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 112 2.4E-32 T 12-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 TSC_c00120 8ad13ed64b93d820cc9b1c349c61dda5 118 SUPERFAMILY SSF55620 4 117 2.48E-30 T 12-10-2018 TSC_c10900 e8346a002a293c6381252774bf611ab3 218 SMART SM00448 1 114 2.5E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c10900 e8346a002a293c6381252774bf611ab3 218 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 215 5.0E-14 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c10900 e8346a002a293c6381252774bf611ab3 218 Pfam PF00072 Response regulator receiver domain 3 115 9.5E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c10900 e8346a002a293c6381252774bf611ab3 218 SUPERFAMILY SSF52172 1 176 4.84E-35 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c10900 e8346a002a293c6381252774bf611ab3 218 SMART SM00862 147 215 1.3E-17 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c10900 e8346a002a293c6381252774bf611ab3 218 Gene3D G3DSA:3.40.50.2300 1 121 5.1E-30 T 12-10-2018 TSC_c10900 e8346a002a293c6381252774bf611ab3 218 Gene3D G3DSA:1.10.10.10 122 217 1.2E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c24110 57851b9546699eced2b7e900f6904f2c 415 Gene3D G3DSA:3.40.50.300 1 150 1.6E-39 T 12-10-2018 TSC_c24110 57851b9546699eced2b7e900f6904f2c 415 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 44 145 6.6E-16 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSC_c24110 57851b9546699eced2b7e900f6904f2c 415 Gene3D G3DSA:1.10.8.60 152 218 4.5E-14 T 12-10-2018 TSC_c24110 57851b9546699eced2b7e900f6904f2c 415 Pfam PF16193 AAA C-terminal domain 176 243 3.4E-19 T 12-10-2018 IPR032423 AAA C-terminal domain TSC_c24110 57851b9546699eced2b7e900f6904f2c 415 Gene3D G3DSA:1.20.272.10 219 321 2.0E-40 T 12-10-2018 TSC_c24110 57851b9546699eced2b7e900f6904f2c 415 SMART SM00382 40 152 7.2E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c24110 57851b9546699eced2b7e900f6904f2c 415 Pfam PF12002 MgsA AAA+ ATPase C terminal 244 409 1.1E-58 T 12-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal TSC_c24110 57851b9546699eced2b7e900f6904f2c 415 Gene3D G3DSA:1.10.3710.10 322 415 2.4E-24 T 12-10-2018 TSC_c24110 57851b9546699eced2b7e900f6904f2c 415 SUPERFAMILY SSF48019 229 412 9.64E-66 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TSC_c24110 57851b9546699eced2b7e900f6904f2c 415 SUPERFAMILY SSF52540 3 216 2.87E-47 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c23380 9f1fbe7a69581e440984369059ec3dda 442 SUPERFAMILY SSF160964 22 193 1.31E-21 T 12-10-2018 TSC_c23380 9f1fbe7a69581e440984369059ec3dda 442 Gene3D G3DSA:1.10.3720.10 199 436 2.8E-63 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c23380 9f1fbe7a69581e440984369059ec3dda 442 SUPERFAMILY SSF161098 189 429 1.7E-54 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c23380 9f1fbe7a69581e440984369059ec3dda 442 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 225 431 2.3E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c21080 670b58e28c0bb282785c14426a5cf378 192 PIRSF PIRSF024608 1 185 2.1E-72 T 12-10-2018 IPR016823 Sulfur oxidation c-type cytochrome SoxX, type II TSC_c21080 670b58e28c0bb282785c14426a5cf378 192 Gene3D G3DSA:1.10.760.10 29 185 1.5E-46 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c21080 670b58e28c0bb282785c14426a5cf378 192 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 93 176 5.9E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c21080 670b58e28c0bb282785c14426a5cf378 192 TIGRFAM TIGR04485 thiosulf_SoxX: sulfur oxidation c-type cytochrome SoxX 99 178 3.6E-24 T 12-10-2018 IPR030999 Sulfur oxidation c-type cytochrome SoxX TSC_c21080 670b58e28c0bb282785c14426a5cf378 192 SUPERFAMILY SSF46626 11 177 1.67E-17 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c12760 576c567a3e1776c427cdaba95c59a996 570 SUPERFAMILY SSF48310 210 551 4.71E-76 T 12-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSC_c12760 576c567a3e1776c427cdaba95c59a996 570 SMART SM00790 2 207 6.4E-80 T 12-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSC_c12760 576c567a3e1776c427cdaba95c59a996 570 Gene3D G3DSA:1.10.599.10 240 547 5.5E-54 T 12-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TSC_c12760 576c567a3e1776c427cdaba95c59a996 570 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 222 549 8.7E-57 T 12-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSC_c12760 576c567a3e1776c427cdaba95c59a996 570 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 3 203 1.2E-50 T 12-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSC_c12760 576c567a3e1776c427cdaba95c59a996 570 Gene3D G3DSA:3.60.9.10 1 210 1.3E-52 T 12-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSC_c12760 576c567a3e1776c427cdaba95c59a996 570 Gene3D G3DSA:1.10.569.10 241 419 5.5E-54 T 12-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TSC_c12760 576c567a3e1776c427cdaba95c59a996 570 SUPERFAMILY SSF56228 3 204 1.7E-49 T 12-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSC_c22750 c8c53245487bfdd34958305c5e94dd3f 781 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 21 781 1.1E-189 T 12-10-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 TSC_c22750 c8c53245487bfdd34958305c5e94dd3f 781 Pfam PF00271 Helicase conserved C-terminal domain 207 317 5.2E-12 T 12-10-2018 IPR001650 Helicase, C-terminal TSC_c22750 c8c53245487bfdd34958305c5e94dd3f 781 SMART SM00847 372 474 1.6E-9 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 TSC_c22750 c8c53245487bfdd34958305c5e94dd3f 781 PIRSF PIRSF005496 10 781 4.4E-206 T 12-10-2018 TSC_c22750 c8c53245487bfdd34958305c5e94dd3f 781 Pfam PF04408 Helicase associated domain (HA2) 373 438 2.2E-12 T 12-10-2018 IPR007502 Helicase-associated domain GO:0004386 TSC_c22750 c8c53245487bfdd34958305c5e94dd3f 781 SMART SM00490 220 317 1.3E-15 T 12-10-2018 IPR001650 Helicase, C-terminal TSC_c22750 c8c53245487bfdd34958305c5e94dd3f 781 SMART SM00487 4 183 1.7E-18 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSC_c22750 c8c53245487bfdd34958305c5e94dd3f 781 Pfam PF08482 ATP-dependent helicase C-terminal 650 781 6.5E-45 T 12-10-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal TSC_c22750 c8c53245487bfdd34958305c5e94dd3f 781 Gene3D G3DSA:1.20.120.1080 352 451 1.7E-8 T 12-10-2018 TSC_c22750 c8c53245487bfdd34958305c5e94dd3f 781 Pfam PF00270 DEAD/DEAH box helicase 14 162 1.0E-7 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSC_c22750 c8c53245487bfdd34958305c5e94dd3f 781 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 118 127 - T 12-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site TSC_c22750 c8c53245487bfdd34958305c5e94dd3f 781 Gene3D G3DSA:3.40.50.300 177 332 1.4E-43 T 12-10-2018 TSC_c22750 c8c53245487bfdd34958305c5e94dd3f 781 SUPERFAMILY SSF52540 22 328 2.76E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c22750 c8c53245487bfdd34958305c5e94dd3f 781 Gene3D G3DSA:3.40.50.300 12 176 1.3E-44 T 12-10-2018 TSC_c04480 d22eb0357d2a91eb872c306e0fce5e28 295 Gene3D G3DSA:3.10.580.10 59 117 2.0E-9 T 12-10-2018 TSC_c04480 d22eb0357d2a91eb872c306e0fce5e28 295 Pfam PF00571 CBS domain 4 54 4.3E-12 T 12-10-2018 IPR000644 CBS domain TSC_c04480 d22eb0357d2a91eb872c306e0fce5e28 295 Pfam PF00571 CBS domain 69 115 2.9E-8 T 12-10-2018 IPR000644 CBS domain TSC_c04480 d22eb0357d2a91eb872c306e0fce5e28 295 SMART SM00267 106 274 2.7E-15 T 12-10-2018 IPR000160 GGDEF domain TSC_c04480 d22eb0357d2a91eb872c306e0fce5e28 295 SUPERFAMILY SSF54631 2 112 4.8E-29 T 12-10-2018 TSC_c04480 d22eb0357d2a91eb872c306e0fce5e28 295 SUPERFAMILY SSF55073 122 267 4.45E-22 T 12-10-2018 IPR029787 Nucleotide cyclase TSC_c04480 d22eb0357d2a91eb872c306e0fce5e28 295 SMART SM00116 69 116 6.4E-7 T 12-10-2018 IPR000644 CBS domain TSC_c04480 d22eb0357d2a91eb872c306e0fce5e28 295 SMART SM00116 11 58 2.2E-9 T 12-10-2018 IPR000644 CBS domain TSC_c04480 d22eb0357d2a91eb872c306e0fce5e28 295 Gene3D G3DSA:3.10.580.10 1 58 6.8E-17 T 12-10-2018 TSC_c04480 d22eb0357d2a91eb872c306e0fce5e28 295 Pfam PF00990 Diguanylate cyclase, GGDEF domain 119 209 5.3E-20 T 12-10-2018 IPR000160 GGDEF domain TSC_c04480 d22eb0357d2a91eb872c306e0fce5e28 295 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 120 205 7.6E-18 T 12-10-2018 IPR000160 GGDEF domain TSC_c04480 d22eb0357d2a91eb872c306e0fce5e28 295 Gene3D G3DSA:3.30.70.270 118 275 1.3E-25 T 12-10-2018 TSC_c00500 5ab124ba3e515a06632badf2bc0b0309 607 SUPERFAMILY SSF56228 3 207 8.11E-75 T 12-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSC_c00500 5ab124ba3e515a06632badf2bc0b0309 607 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 238 601 4.0E-120 T 12-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSC_c00500 5ab124ba3e515a06632badf2bc0b0309 607 Gene3D G3DSA:1.10.599.10 246 601 1.5E-119 T 12-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TSC_c00500 5ab124ba3e515a06632badf2bc0b0309 607 SMART SM00790 5 206 4.3E-122 T 12-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSC_c00500 5ab124ba3e515a06632badf2bc0b0309 607 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 8 204 2.1E-75 T 12-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSC_c00500 5ab124ba3e515a06632badf2bc0b0309 607 Gene3D G3DSA:1.10.569.10 247 430 1.5E-119 T 12-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TSC_c00500 5ab124ba3e515a06632badf2bc0b0309 607 SUPERFAMILY SSF48310 213 601 4.71E-121 T 12-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSC_c00500 5ab124ba3e515a06632badf2bc0b0309 607 Gene3D G3DSA:3.60.9.10 2 209 1.7E-81 T 12-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSC_c04950 7cece9f201ffd4f3f053d1a937e7c790 217 SUPERFAMILY SSF46894 145 211 4.08E-22 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSC_c04950 7cece9f201ffd4f3f053d1a937e7c790 217 SUPERFAMILY SSF52172 2 132 3.56E-37 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c04950 7cece9f201ffd4f3f053d1a937e7c790 217 Gene3D G3DSA:3.40.50.12740 2 211 2.5E-75 T 12-10-2018 TSC_c04950 7cece9f201ffd4f3f053d1a937e7c790 217 SMART SM00421 148 205 6.9E-24 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c04950 7cece9f201ffd4f3f053d1a937e7c790 217 Pfam PF00072 Response regulator receiver domain 4 115 1.4E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c04950 7cece9f201ffd4f3f053d1a937e7c790 217 SMART SM00448 2 115 2.1E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c04950 7cece9f201ffd4f3f053d1a937e7c790 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 3.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c04950 7cece9f201ffd4f3f053d1a937e7c790 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 3.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c04950 7cece9f201ffd4f3f053d1a937e7c790 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 3.4E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c04950 7cece9f201ffd4f3f053d1a937e7c790 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 1.1E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c03930 ce07c87a324c93dd52c49407643902e9 920 Gene3D G3DSA:1.25.40.10 496 691 2.9E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c03930 ce07c87a324c93dd52c49407643902e9 920 SUPERFAMILY SSF48452 506 711 5.2E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c15170 173d892d33a050feb97bb5187941d559 710 Gene3D G3DSA:1.10.3810.10 57 248 4.7E-55 T 12-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSC_c15170 173d892d33a050feb97bb5187941d559 710 SUPERFAMILY SSF53955 42 256 1.07E-56 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily TSC_c15170 173d892d33a050feb97bb5187941d559 710 SUPERFAMILY SSF56601 216 665 1.11E-107 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSC_c15170 173d892d33a050feb97bb5187941d559 710 Pfam PF00905 Penicillin binding protein transpeptidase domain 343 584 1.2E-27 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TSC_c15170 173d892d33a050feb97bb5187941d559 710 Pfam PF00912 Transglycosylase 63 232 4.1E-53 T 12-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSC_c15170 173d892d33a050feb97bb5187941d559 710 Gene3D G3DSA:3.40.710.10 279 666 8.6E-113 T 12-10-2018 TSC_c03060 bae59f63f0ac575ae17017e5a8d2a257 101 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 2.1E-32 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c03060 bae59f63f0ac575ae17017e5a8d2a257 101 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 101 25.196 T 12-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c03060 bae59f63f0ac575ae17017e5a8d2a257 101 SUPERFAMILY SSF141091 1 99 5.62E-35 T 12-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c03060 bae59f63f0ac575ae17017e5a8d2a257 101 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 99 2.9E-37 T 12-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c15430 2ce5a39ab643594b98613a693a38d3de 275 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 266 1.9E-26 T 12-10-2018 TSC_c15430 2ce5a39ab643594b98613a693a38d3de 275 SUPERFAMILY SSF56784 1 270 2.4E-40 T 12-10-2018 IPR036412 HAD-like superfamily TSC_c15430 2ce5a39ab643594b98613a693a38d3de 275 Gene3D G3DSA:3.40.50.1000 3 265 1.7E-38 T 12-10-2018 IPR023214 HAD superfamily TSC_c15430 2ce5a39ab643594b98613a693a38d3de 275 Gene3D G3DSA:3.30.1240.10 89 195 1.7E-38 T 12-10-2018 TSC_c15430 2ce5a39ab643594b98613a693a38d3de 275 ProSitePatterns PS01229 Hypothetical cof family signature 2. 220 242 - T 12-10-2018 TSC_c01200 a06571afe4090a35cf70a8c2334aef96 905 Gene3D G3DSA:3.40.50.970 489 722 1.0E-102 T 12-10-2018 TSC_c01200 a06571afe4090a35cf70a8c2334aef96 905 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 91 310 1.2E-8 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TSC_c01200 a06571afe4090a35cf70a8c2334aef96 905 Gene3D G3DSA:3.40.50.920 727 904 7.8E-60 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSC_c01200 a06571afe4090a35cf70a8c2334aef96 905 SUPERFAMILY SSF52518 69 483 3.75E-124 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c01200 a06571afe4090a35cf70a8c2334aef96 905 SUPERFAMILY SSF52922 723 902 1.57E-47 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSC_c01200 a06571afe4090a35cf70a8c2334aef96 905 PIRSF PIRSF000156 8 905 0.0 T 12-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TSC_c01200 a06571afe4090a35cf70a8c2334aef96 905 SUPERFAMILY SSF52518 491 717 1.53E-89 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c01200 a06571afe4090a35cf70a8c2334aef96 905 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 23 902 0.0 T 12-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TSC_c01200 a06571afe4090a35cf70a8c2334aef96 905 Gene3D G3DSA:3.40.50.970 68 488 5.9E-123 T 12-10-2018 TSC_c15460 0f949d02b87e28ced1509e09b4322627 220 SMART SM00862 147 216 3.6E-14 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c15460 0f949d02b87e28ced1509e09b4322627 220 Pfam PF00072 Response regulator receiver domain 3 115 2.2E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c15460 0f949d02b87e28ced1509e09b4322627 220 SUPERFAMILY SSF52172 2 174 6.55E-35 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c15460 0f949d02b87e28ced1509e09b4322627 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 204 1.8E-12 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c15460 0f949d02b87e28ced1509e09b4322627 220 Gene3D G3DSA:3.40.50.2300 1 123 1.8E-32 T 12-10-2018 TSC_c15460 0f949d02b87e28ced1509e09b4322627 220 Gene3D G3DSA:1.10.10.10 124 217 6.8E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c15460 0f949d02b87e28ced1509e09b4322627 220 SMART SM00448 1 114 1.1E-36 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c00550 01dc00442bcafd0b7688bb7cbc94ac1b 112 SUPERFAMILY SSF58113 5 107 3.92E-5 T 12-10-2018 TSC_c00550 01dc00442bcafd0b7688bb7cbc94ac1b 112 Gene3D G3DSA:1.20.120.20 2 111 1.9E-5 T 12-10-2018 TSC_c21010 5518720f3a59ff4b4e1caa70e1abf0b5 427 Gene3D G3DSA:2.60.40.650 281 407 1.8E-45 T 12-10-2018 TSC_c21010 5518720f3a59ff4b4e1caa70e1abf0b5 427 SUPERFAMILY SSF56524 68 312 2.09E-72 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TSC_c21010 5518720f3a59ff4b4e1caa70e1abf0b5 427 Pfam PF00174 Oxidoreductase molybdopterin binding domain 94 256 6.2E-53 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 TSC_c21010 5518720f3a59ff4b4e1caa70e1abf0b5 427 TIGRFAM TIGR04555 sulfite_DH_soxC: sulfite dehydrogenase 3 404 2.8E-177 T 12-10-2018 IPR030835 Sulfite dehydrogenase SoxC TSC_c21010 5518720f3a59ff4b4e1caa70e1abf0b5 427 SUPERFAMILY SSF81296 282 396 3.78E-30 T 12-10-2018 IPR014756 Immunoglobulin E-set TSC_c21010 5518720f3a59ff4b4e1caa70e1abf0b5 427 Gene3D G3DSA:3.90.420.10 25 280 1.6E-85 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TSC_c21010 5518720f3a59ff4b4e1caa70e1abf0b5 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 224 237 2.3E-24 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TSC_c21010 5518720f3a59ff4b4e1caa70e1abf0b5 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 82 98 2.3E-24 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TSC_c21010 5518720f3a59ff4b4e1caa70e1abf0b5 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 134 145 2.3E-24 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TSC_c21010 5518720f3a59ff4b4e1caa70e1abf0b5 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 240 253 2.3E-24 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TSC_c21010 5518720f3a59ff4b4e1caa70e1abf0b5 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 207 223 2.3E-24 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TSC_c21010 5518720f3a59ff4b4e1caa70e1abf0b5 427 PRINTS PR00407 Eukaryotic molybdopterin domain signature 317 329 2.3E-24 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TSC_c21010 5518720f3a59ff4b4e1caa70e1abf0b5 427 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 279 392 3.3E-16 T 12-10-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 TSC_c10590 d72e6336e5c70a5ef04517f2350bb560 862 Gene3D G3DSA:3.30.1490.20 11 238 3.4E-87 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSC_c10590 d72e6336e5c70a5ef04517f2350bb560 862 Gene3D G3DSA:3.50.30.10 378 502 5.6E-65 T 12-10-2018 TSC_c10590 d72e6336e5c70a5ef04517f2350bb560 862 SUPERFAMILY SSF51621 513 856 4.19E-109 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSC_c10590 d72e6336e5c70a5ef04517f2350bb560 862 TIGRFAM TIGR01828 pyru_phos_dikin: pyruvate, phosphate dikinase 1 853 0.0 T 12-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TSC_c10590 d72e6336e5c70a5ef04517f2350bb560 862 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 510 852 3.1E-84 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TSC_c10590 d72e6336e5c70a5ef04517f2350bb560 862 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 443 454 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 TSC_c10590 d72e6336e5c70a5ef04517f2350bb560 862 PIRSF PIRSF000853 1 861 0.0 T 12-10-2018 IPR010121 Pyruvate, phosphate dikinase GO:0006090|GO:0050242 KEGG: 00620+2.7.9.1|KEGG: 00710+2.7.9.1|KEGG: 00720+2.7.9.1|MetaCyc: PWY-241|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117 TSC_c10590 d72e6336e5c70a5ef04517f2350bb560 862 Gene3D G3DSA:3.20.20.60 525 856 5.3E-132 T 12-10-2018 TSC_c10590 d72e6336e5c70a5ef04517f2350bb560 862 Pfam PF00391 PEP-utilising enzyme, mobile domain 417 496 4.6E-25 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TSC_c10590 d72e6336e5c70a5ef04517f2350bb560 862 SUPERFAMILY SSF56059 1 374 5.18E-126 T 12-10-2018 TSC_c10590 d72e6336e5c70a5ef04517f2350bb560 862 Gene3D G3DSA:3.30.470.20 239 336 4.7E-40 T 12-10-2018 TSC_c10590 d72e6336e5c70a5ef04517f2350bb560 862 Gene3D G3DSA:1.20.80.30 107 193 3.4E-87 T 12-10-2018 TSC_c10590 d72e6336e5c70a5ef04517f2350bb560 862 Gene3D G3DSA:1.10.189.10 340 522 5.6E-65 T 12-10-2018 TSC_c10590 d72e6336e5c70a5ef04517f2350bb560 862 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 745 763 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TSC_c10590 d72e6336e5c70a5ef04517f2350bb560 862 SUPERFAMILY SSF52009 380 504 2.88E-35 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TSC_c10590 d72e6336e5c70a5ef04517f2350bb560 862 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 298 351 1.3E-9 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TSC_c10590 d72e6336e5c70a5ef04517f2350bb560 862 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 57 284 2.1E-30 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TSC_c08270 398c82860ec603d64eebc0282e6dae66 253 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 TSC_c08270 398c82860ec603d64eebc0282e6dae66 253 SUPERFAMILY SSF52096 6 253 1.46E-78 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSC_c08270 398c82860ec603d64eebc0282e6dae66 253 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 253 6.0E-54 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSC_c08270 398c82860ec603d64eebc0282e6dae66 253 Gene3D G3DSA:1.10.12.10 199 253 6.9E-27 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TSC_c08270 398c82860ec603d64eebc0282e6dae66 253 Gene3D G3DSA:3.90.226.10 1 198 1.3E-73 T 12-10-2018 TSC_c15410 175dabc49bac4d8d67f23eabb6591f2c 581 SUPERFAMILY SSF50249 1 103 6.09E-30 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c15410 175dabc49bac4d8d67f23eabb6591f2c 581 Pfam PF00152 tRNA synthetases class II (D, K and N) 123 551 2.9E-109 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c15410 175dabc49bac4d8d67f23eabb6591f2c 581 Gene3D G3DSA:2.40.50.140 1 106 5.1E-32 T 12-10-2018 TSC_c15410 175dabc49bac4d8d67f23eabb6591f2c 581 Gene3D G3DSA:3.30.930.10 140 573 7.5E-194 T 12-10-2018 TSC_c15410 175dabc49bac4d8d67f23eabb6591f2c 581 PRINTS PR01042 Aspartyl-tRNA synthetase signature 468 484 2.0E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c15410 175dabc49bac4d8d67f23eabb6591f2c 581 PRINTS PR01042 Aspartyl-tRNA synthetase signature 512 526 2.0E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c15410 175dabc49bac4d8d67f23eabb6591f2c 581 PRINTS PR01042 Aspartyl-tRNA synthetase signature 213 226 2.0E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c15410 175dabc49bac4d8d67f23eabb6591f2c 581 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 208 2.0E-26 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c15410 175dabc49bac4d8d67f23eabb6591f2c 581 Pfam PF02938 GAD domain 316 400 8.1E-25 T 12-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 TSC_c15410 175dabc49bac4d8d67f23eabb6591f2c 581 Pfam PF01336 OB-fold nucleic acid binding domain 19 100 7.7E-14 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TSC_c15410 175dabc49bac4d8d67f23eabb6591f2c 581 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 2 578 34.338 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 TSC_c15410 175dabc49bac4d8d67f23eabb6591f2c 581 SUPERFAMILY SSF55261 295 413 3.11E-33 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TSC_c15410 175dabc49bac4d8d67f23eabb6591f2c 581 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 575 2.3E-220 T 12-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 TSC_c15410 175dabc49bac4d8d67f23eabb6591f2c 581 Gene3D G3DSA:3.30.1360.30 278 415 7.5E-194 T 12-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 TSC_c15410 175dabc49bac4d8d67f23eabb6591f2c 581 SUPERFAMILY SSF55681 105 576 7.37E-109 T 12-10-2018 TSC_c05890 8dfc6edfc727de7ce235f0517f2f1b7e 173 Pfam PF02620 Uncharacterized ACR, COG1399 55 169 5.2E-27 T 12-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD TSC_c20060 7e0bd73378fa4d3066cabd745038df0d 217 ProSitePatterns PS01155 Endonuclease III family signature. 111 140 - T 12-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 TSC_c20060 7e0bd73378fa4d3066cabd745038df0d 217 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 43 177 3.9E-23 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSC_c20060 7e0bd73378fa4d3066cabd745038df0d 217 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 196 212 - T 12-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TSC_c20060 7e0bd73378fa4d3066cabd745038df0d 217 SMART SM00478 47 194 1.0E-59 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSC_c20060 7e0bd73378fa4d3066cabd745038df0d 217 Gene3D G3DSA:1.10.1670.10 20 212 1.4E-76 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TSC_c20060 7e0bd73378fa4d3066cabd745038df0d 217 Gene3D G3DSA:1.10.340.30 30 141 1.4E-76 T 12-10-2018 TSC_c20060 7e0bd73378fa4d3066cabd745038df0d 217 PIRSF PIRSF001435 7 217 4.5E-52 T 12-10-2018 TSC_c20060 7e0bd73378fa4d3066cabd745038df0d 217 Hamap MF_00942 Endonuclease III [nth]. 9 217 37.563 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 TSC_c20060 7e0bd73378fa4d3066cabd745038df0d 217 SUPERFAMILY SSF48150 12 215 2.2E-71 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TSC_c20060 7e0bd73378fa4d3066cabd745038df0d 217 TIGRFAM TIGR01083 nth: endonuclease III 13 203 1.6E-80 T 12-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 TSC_c03240 244c419c80ade9d4276e4c03700b1b39 538 Pfam PF08308 PEGA domain 190 256 2.7E-18 T 12-10-2018 IPR013229 PEGA TSC_c03240 244c419c80ade9d4276e4c03700b1b39 538 Pfam PF08308 PEGA domain 480 535 4.2E-7 T 12-10-2018 IPR013229 PEGA TSC_c03240 244c419c80ade9d4276e4c03700b1b39 538 Pfam PF08308 PEGA domain 402 469 3.3E-19 T 12-10-2018 IPR013229 PEGA TSC_c03240 244c419c80ade9d4276e4c03700b1b39 538 Pfam PF08308 PEGA domain 332 398 2.7E-19 T 12-10-2018 IPR013229 PEGA TSC_c03240 244c419c80ade9d4276e4c03700b1b39 538 Pfam PF08308 PEGA domain 261 328 4.1E-21 T 12-10-2018 IPR013229 PEGA TSC_c03240 244c419c80ade9d4276e4c03700b1b39 538 Pfam PF14326 Domain of unknown function (DUF4384) 50 130 1.0E-28 T 12-10-2018 IPR025493 Domain of unknown function DUF4384 TSC_c03240 244c419c80ade9d4276e4c03700b1b39 538 Gene3D G3DSA:2.60.40.1120 265 326 2.9E-6 T 12-10-2018 TSC_c03240 244c419c80ade9d4276e4c03700b1b39 538 Gene3D G3DSA:2.60.40.1120 347 397 2.9E-5 T 12-10-2018 TSC_c20200 055bee9befff0176afd726f8d504dcc6 872 SUPERFAMILY SSF48452 342 521 2.01E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c20200 055bee9befff0176afd726f8d504dcc6 872 Gene3D G3DSA:1.10.10.10 664 748 3.0E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c20200 055bee9befff0176afd726f8d504dcc6 872 Pfam PF03704 Bacterial transcriptional activator domain 810 871 2.9E-5 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TSC_c20200 055bee9befff0176afd726f8d504dcc6 872 SMART SM01043 754 872 0.0098 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TSC_c20200 055bee9befff0176afd726f8d504dcc6 872 SUPERFAMILY SSF48452 767 871 1.96E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c20200 055bee9befff0176afd726f8d504dcc6 872 Gene3D G3DSA:1.25.40.10 252 526 4.3E-15 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c20200 055bee9befff0176afd726f8d504dcc6 872 Gene3D G3DSA:1.25.40.10 749 872 3.0E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c03490 57e9eca477f1f3e8c3afa0c25f019b6e 378 SUPERFAMILY SSF51905 4 311 6.05E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c03490 57e9eca477f1f3e8c3afa0c25f019b6e 378 SUPERFAMILY SSF51905 114 241 1.2E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c03490 57e9eca477f1f3e8c3afa0c25f019b6e 378 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.1E-6 T 12-10-2018 TSC_c03490 57e9eca477f1f3e8c3afa0c25f019b6e 378 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 1.1E-6 T 12-10-2018 TSC_c03490 57e9eca477f1f3e8c3afa0c25f019b6e 378 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 1.1E-6 T 12-10-2018 TSC_c03490 57e9eca477f1f3e8c3afa0c25f019b6e 378 Gene3D G3DSA:3.50.50.100 1 377 7.3E-90 T 12-10-2018 TSC_c03490 57e9eca477f1f3e8c3afa0c25f019b6e 378 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 284 1.6E-19 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSC_c17260 9ee131f9b67736012891acfda7423be9 746 Pfam PF00990 Diguanylate cyclase, GGDEF domain 591 741 6.6E-40 T 12-10-2018 IPR000160 GGDEF domain TSC_c17260 9ee131f9b67736012891acfda7423be9 746 SUPERFAMILY SSF55781 267 411 8.29E-10 T 12-10-2018 TSC_c17260 9ee131f9b67736012891acfda7423be9 746 Pfam PF13185 GAF domain 265 405 8.7E-9 T 12-10-2018 IPR003018 GAF domain GO:0005515 TSC_c17260 9ee131f9b67736012891acfda7423be9 746 Pfam PF13185 GAF domain 140 239 5.3E-10 T 12-10-2018 IPR003018 GAF domain GO:0005515 TSC_c17260 9ee131f9b67736012891acfda7423be9 746 SUPERFAMILY SSF55781 412 588 3.05E-9 T 12-10-2018 TSC_c17260 9ee131f9b67736012891acfda7423be9 746 Gene3D G3DSA:3.30.450.40 246 413 3.5E-16 T 12-10-2018 IPR029016 GAF-like domain superfamily TSC_c17260 9ee131f9b67736012891acfda7423be9 746 Gene3D G3DSA:3.30.450.40 414 588 4.3E-13 T 12-10-2018 IPR029016 GAF-like domain superfamily TSC_c17260 9ee131f9b67736012891acfda7423be9 746 Gene3D G3DSA:3.30.450.40 86 245 6.0E-17 T 12-10-2018 IPR029016 GAF-like domain superfamily TSC_c17260 9ee131f9b67736012891acfda7423be9 746 SUPERFAMILY SSF55073 596 741 1.1E-41 T 12-10-2018 IPR029787 Nucleotide cyclase TSC_c17260 9ee131f9b67736012891acfda7423be9 746 Gene3D G3DSA:3.30.70.270 589 746 6.1E-50 T 12-10-2018 TSC_c17260 9ee131f9b67736012891acfda7423be9 746 SMART SM00267 580 745 6.6E-46 T 12-10-2018 IPR000160 GGDEF domain TSC_c17260 9ee131f9b67736012891acfda7423be9 746 SMART SM00065 427 588 0.03 T 12-10-2018 IPR003018 GAF domain GO:0005515 TSC_c17260 9ee131f9b67736012891acfda7423be9 746 SMART SM00065 266 414 0.06 T 12-10-2018 IPR003018 GAF domain GO:0005515 TSC_c17260 9ee131f9b67736012891acfda7423be9 746 SMART SM00065 83 252 5.1E-8 T 12-10-2018 IPR003018 GAF domain GO:0005515 TSC_c17260 9ee131f9b67736012891acfda7423be9 746 SUPERFAMILY SSF55781 87 243 1.96E-19 T 12-10-2018 TSC_c17260 9ee131f9b67736012891acfda7423be9 746 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 587 741 3.0E-41 T 12-10-2018 IPR000160 GGDEF domain TSC_c01690 9434f1bef8f1fd83538ec1e58b364be2 431 SMART SM01027 228 351 9.5E-56 T 12-10-2018 IPR022712 Beta-Casp domain TSC_c01690 9434f1bef8f1fd83538ec1e58b364be2 431 Gene3D G3DSA:3.40.50.10890 196 377 4.5E-160 T 12-10-2018 TSC_c01690 9434f1bef8f1fd83538ec1e58b364be2 431 SUPERFAMILY SSF56281 1 430 8.91E-133 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c01690 9434f1bef8f1fd83538ec1e58b364be2 431 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 365 414 1.4E-12 T 12-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TSC_c01690 9434f1bef8f1fd83538ec1e58b364be2 431 Pfam PF00753 Metallo-beta-lactamase superfamily 12 186 1.2E-17 T 12-10-2018 IPR001279 Metallo-beta-lactamase TSC_c01690 9434f1bef8f1fd83538ec1e58b364be2 431 Pfam PF10996 Beta-Casp domain 228 351 2.7E-25 T 12-10-2018 IPR022712 Beta-Casp domain TSC_c01690 9434f1bef8f1fd83538ec1e58b364be2 431 Gene3D G3DSA:3.60.15.10 6 405 4.5E-160 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c01690 9434f1bef8f1fd83538ec1e58b364be2 431 SMART SM00849 13 216 5.6E-23 T 12-10-2018 IPR001279 Metallo-beta-lactamase TSC_c12230 558f76ac86951492a58fa957bc52fc72 307 SUPERFAMILY SSF142754 6 305 4.58E-106 T 12-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TSC_c12230 558f76ac86951492a58fa957bc52fc72 307 Pfam PF02445 Quinolinate synthetase A protein 9 304 2.9E-111 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TSC_c12230 558f76ac86951492a58fa957bc52fc72 307 Gene3D G3DSA:3.40.50.10800 172 262 4.5E-112 T 12-10-2018 TSC_c12230 558f76ac86951492a58fa957bc52fc72 307 Gene3D G3DSA:3.40.50.10800 88 304 4.5E-112 T 12-10-2018 TSC_c12230 558f76ac86951492a58fa957bc52fc72 307 Gene3D G3DSA:3.40.50.10800 8 287 4.5E-112 T 12-10-2018 TSC_c12230 558f76ac86951492a58fa957bc52fc72 307 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 1 306 2.1E-97 T 12-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TSC_c12230 558f76ac86951492a58fa957bc52fc72 307 Hamap MF_00568 Quinolinate synthase A [nadA]. 4 306 42.241 T 12-10-2018 IPR023066 Quinolinate synthase A, type 2 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 TSC_c16950 99ce857441c1b5d8e09e1df86beb1540 262 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 7 18 - T 12-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 TSC_c16950 99ce857441c1b5d8e09e1df86beb1540 262 Gene3D G3DSA:1.10.287.610 98 153 4.8E-95 T 12-10-2018 TSC_c16950 99ce857441c1b5d8e09e1df86beb1540 262 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 5 226 2.3E-95 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c16950 99ce857441c1b5d8e09e1df86beb1540 262 Gene3D G3DSA:3.40.50.10490 11 216 4.8E-95 T 12-10-2018 TSC_c16950 99ce857441c1b5d8e09e1df86beb1540 262 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 3 226 39.973 T 12-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c16950 99ce857441c1b5d8e09e1df86beb1540 262 SUPERFAMILY SSF52313 7 233 7.19E-88 T 12-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily TSC_c16950 99ce857441c1b5d8e09e1df86beb1540 262 Pfam PF00318 Ribosomal protein S2 10 223 9.0E-91 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c16950 99ce857441c1b5d8e09e1df86beb1540 262 PRINTS PR00395 Ribosomal protein S2 signature 38 47 2.8E-40 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c16950 99ce857441c1b5d8e09e1df86beb1540 262 PRINTS PR00395 Ribosomal protein S2 signature 197 211 2.8E-40 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c16950 99ce857441c1b5d8e09e1df86beb1540 262 PRINTS PR00395 Ribosomal protein S2 signature 88 105 2.8E-40 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c16950 99ce857441c1b5d8e09e1df86beb1540 262 PRINTS PR00395 Ribosomal protein S2 signature 159 176 2.8E-40 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c16950 99ce857441c1b5d8e09e1df86beb1540 262 PRINTS PR00395 Ribosomal protein S2 signature 7 25 2.8E-40 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c16950 99ce857441c1b5d8e09e1df86beb1540 262 PRINTS PR00395 Ribosomal protein S2 signature 176 187 2.8E-40 T 12-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c11490 ce21285c066ea3672f866ddb7972680e 484 SUPERFAMILY SSF52540 256 475 2.07E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c11490 ce21285c066ea3672f866ddb7972680e 484 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 218 240 2.9E-8 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSC_c11490 ce21285c066ea3672f866ddb7972680e 484 ProSitePatterns PS00211 ABC transporters family signature. 387 401 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c11490 ce21285c066ea3672f866ddb7972680e 484 SUPERFAMILY SSF52540 4 241 1.07E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c11490 ce21285c066ea3672f866ddb7972680e 484 Pfam PF00005 ABC transporter 273 414 2.5E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c11490 ce21285c066ea3672f866ddb7972680e 484 Gene3D G3DSA:3.40.50.300 2 245 5.0E-60 T 12-10-2018 TSC_c11490 ce21285c066ea3672f866ddb7972680e 484 SMART SM00382 28 220 1.4E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c11490 ce21285c066ea3672f866ddb7972680e 484 SMART SM00382 282 463 1.6E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c11490 ce21285c066ea3672f866ddb7972680e 484 Pfam PF00005 ABC transporter 21 170 7.5E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c11490 ce21285c066ea3672f866ddb7972680e 484 Gene3D G3DSA:3.40.50.300 253 484 2.2E-60 T 12-10-2018 TSC_c13930 2ecb24d448ef607b855e2a23d81f6eb3 344 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 344 44.793 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 TSC_c13930 2ecb24d448ef607b855e2a23d81f6eb3 344 Pfam PF02547 Queuosine biosynthesis protein 4 343 5.9E-131 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 TSC_c13930 2ecb24d448ef607b855e2a23d81f6eb3 344 Gene3D G3DSA:3.40.1780.10 14 343 6.3E-118 T 12-10-2018 TSC_c13930 2ecb24d448ef607b855e2a23d81f6eb3 344 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 344 8.5E-109 T 12-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 TSC_c13930 2ecb24d448ef607b855e2a23d81f6eb3 344 SUPERFAMILY SSF111337 1 344 8.76E-130 T 12-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 TSC_c13930 2ecb24d448ef607b855e2a23d81f6eb3 344 Gene3D G3DSA:2.40.10.240 65 167 6.3E-118 T 12-10-2018 TSC_c06530 6fb8bce38ff670627b00e6c5ee590db7 314 Gene3D G3DSA:3.40.50.300 45 255 5.6E-85 T 12-10-2018 TSC_c06530 6fb8bce38ff670627b00e6c5ee590db7 314 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 18 306 5.5E-98 T 12-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSC_c06530 6fb8bce38ff670627b00e6c5ee590db7 314 Pfam PF03308 ArgK protein 23 278 5.7E-98 T 12-10-2018 TSC_c06530 6fb8bce38ff670627b00e6c5ee590db7 314 SUPERFAMILY SSF52540 5 283 2.52E-79 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c06530 6fb8bce38ff670627b00e6c5ee590db7 314 Gene3D G3DSA:1.20.5.170 4 44 9.5E-7 T 12-10-2018 TSC_c23040 a9f5214bb45bfa17eee7bfdc4931a1e4 440 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 268 419 1.4E-65 T 12-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain TSC_c23040 a9f5214bb45bfa17eee7bfdc4931a1e4 440 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 2 174 6.8E-29 T 12-10-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 TSC_c23040 a9f5214bb45bfa17eee7bfdc4931a1e4 440 Gene3D G3DSA:3.40.1080.10 1 179 3.9E-70 T 12-10-2018 TSC_c23040 a9f5214bb45bfa17eee7bfdc4931a1e4 440 SUPERFAMILY SSF100950 3 219 2.63E-54 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TSC_c23040 a9f5214bb45bfa17eee7bfdc4931a1e4 440 SUPERFAMILY SSF100950 186 427 1.13E-70 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TSC_c23040 a9f5214bb45bfa17eee7bfdc4931a1e4 440 Gene3D G3DSA:3.30.750.70 182 285 2.0E-42 T 12-10-2018 TSC_c23040 a9f5214bb45bfa17eee7bfdc4931a1e4 440 Gene3D G3DSA:3.40.1080.20 287 428 1.0E-65 T 12-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily TSC_c05670 7c8c139b0b0208326772d1f2a5e5bb1d 196 Gene3D G3DSA:3.30.1370.50 121 195 1.0E-23 T 12-10-2018 IPR036867 R3H domain superfamily GO:0003676 TSC_c05670 7c8c139b0b0208326772d1f2a5e5bb1d 196 SUPERFAMILY SSF82708 140 184 6.87E-10 T 12-10-2018 IPR036867 R3H domain superfamily GO:0003676 TSC_c05670 7c8c139b0b0208326772d1f2a5e5bb1d 196 Gene3D G3DSA:3.30.300.20 36 120 2.5E-16 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TSC_c05670 7c8c139b0b0208326772d1f2a5e5bb1d 196 SMART SM00393 106 185 1.1E-22 T 12-10-2018 IPR001374 R3H domain GO:0003676 TSC_c05670 7c8c139b0b0208326772d1f2a5e5bb1d 196 Pfam PF01424 R3H domain 126 184 1.3E-16 T 12-10-2018 IPR001374 R3H domain GO:0003676 TSC_c05670 7c8c139b0b0208326772d1f2a5e5bb1d 196 Pfam PF13083 KH domain 58 112 1.4E-9 T 12-10-2018 TSC_c06180 2cea2d384fcd36ff22a7693efe1e1c73 194 SUPERFAMILY SSF54211 1 84 6.07E-27 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c06180 2cea2d384fcd36ff22a7693efe1e1c73 194 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 194 37.135 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TSC_c06180 2cea2d384fcd36ff22a7693efe1e1c73 194 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TSC_c06180 2cea2d384fcd36ff22a7693efe1e1c73 194 SUPERFAMILY SSF54211 87 181 2.53E-26 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c06180 2cea2d384fcd36ff22a7693efe1e1c73 194 Gene3D G3DSA:3.30.230.40 1 89 1.2E-30 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 TSC_c06180 2cea2d384fcd36ff22a7693efe1e1c73 194 Gene3D G3DSA:3.30.230.40 90 194 7.7E-32 T 12-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 TSC_c06180 2cea2d384fcd36ff22a7693efe1e1c73 194 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 61 74 - T 12-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TSC_c06180 2cea2d384fcd36ff22a7693efe1e1c73 194 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 31 176 2.9E-54 T 12-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 TSC_c04510 59ed45cf0afff71ad26e8b6d783fac44 414 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 3 414 49.394 T 12-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TSC_c04510 59ed45cf0afff71ad26e8b6d783fac44 414 Gene3D G3DSA:3.90.550.10 2 295 1.0E-88 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c04510 59ed45cf0afff71ad26e8b6d783fac44 414 SUPERFAMILY SSF51161 302 412 1.04E-18 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily TSC_c04510 59ed45cf0afff71ad26e8b6d783fac44 414 SUPERFAMILY SSF53448 3 381 1.41E-76 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c04510 59ed45cf0afff71ad26e8b6d783fac44 414 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 102 110 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TSC_c04510 59ed45cf0afff71ad26e8b6d783fac44 414 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 12 31 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TSC_c04510 59ed45cf0afff71ad26e8b6d783fac44 414 Gene3D G3DSA:2.160.10.10 296 412 3.1E-33 T 12-10-2018 TSC_c04510 59ed45cf0afff71ad26e8b6d783fac44 414 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 6 387 5.7E-147 T 12-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TSC_c04510 59ed45cf0afff71ad26e8b6d783fac44 414 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 200 210 - T 12-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 TSC_c04510 59ed45cf0afff71ad26e8b6d783fac44 414 Pfam PF00483 Nucleotidyl transferase 8 280 4.2E-65 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TSC_c15670 0e1e46a50ff95c1766ea3689c452f69d 972 Gene3D G3DSA:3.90.1570.50 80 253 2.7E-21 T 12-10-2018 TSC_c15670 0e1e46a50ff95c1766ea3689c452f69d 972 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 10 667 1.4E-145 T 12-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 TSC_c15670 0e1e46a50ff95c1766ea3689c452f69d 972 Pfam PF04851 Type III restriction enzyme, res subunit 259 417 2.6E-21 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TSC_c15670 0e1e46a50ff95c1766ea3689c452f69d 972 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 5 195 1.2E-29 T 12-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 TSC_c15670 0e1e46a50ff95c1766ea3689c452f69d 972 SMART SM00487 256 445 1.0E-18 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSC_c15670 0e1e46a50ff95c1766ea3689c452f69d 972 Gene3D G3DSA:3.40.50.300 442 677 1.8E-37 T 12-10-2018 TSC_c15670 0e1e46a50ff95c1766ea3689c452f69d 972 Gene3D G3DSA:3.40.50.300 259 436 8.0E-47 T 12-10-2018 TSC_c15670 0e1e46a50ff95c1766ea3689c452f69d 972 SUPERFAMILY SSF52540 224 472 1.5E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c01750 540ab6b035be9e9dd303f0e49f68b350 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 5 53 1.7E-22 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c01750 540ab6b035be9e9dd303f0e49f68b350 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 19.772 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c01750 540ab6b035be9e9dd303f0e49f68b350 54 Pfam PF00471 Ribosomal protein L33 7 53 6.2E-24 T 12-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c01750 540ab6b035be9e9dd303f0e49f68b350 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 12-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c01750 540ab6b035be9e9dd303f0e49f68b350 54 SUPERFAMILY SSF57829 2 53 3.89E-21 T 12-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 TSC_c01750 540ab6b035be9e9dd303f0e49f68b350 54 Gene3D G3DSA:2.20.28.120 1 54 8.0E-28 T 12-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c10800 e37ea110324ccf21bb66d73bdd5c5784 225 Gene3D G3DSA:3.40.1410.10 72 225 7.0E-51 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TSC_c10800 e37ea110324ccf21bb66d73bdd5c5784 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 57 1.4E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSC_c10800 e37ea110324ccf21bb66d73bdd5c5784 225 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 27 41 1.4E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSC_c10800 e37ea110324ccf21bb66d73bdd5c5784 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 67 7.2E-20 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSC_c10800 e37ea110324ccf21bb66d73bdd5c5784 225 SUPERFAMILY SSF46785 3 78 2.14E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c10800 e37ea110324ccf21bb66d73bdd5c5784 225 SMART SM00866 86 219 3.6E-46 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TSC_c10800 e37ea110324ccf21bb66d73bdd5c5784 225 Pfam PF07702 UTRA domain 87 219 6.0E-41 T 12-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 TSC_c10800 e37ea110324ccf21bb66d73bdd5c5784 225 Gene3D G3DSA:1.10.10.10 1 71 1.8E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c10800 e37ea110324ccf21bb66d73bdd5c5784 225 SUPERFAMILY SSF64288 55 224 2.98E-51 T 12-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily TSC_c10800 e37ea110324ccf21bb66d73bdd5c5784 225 SMART SM00345 10 67 3.8E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSC_c11570 0ff63743a10a88afe24fe2beed3ac51f 347 ProDom PD005364 ALDOLASE 4-HYDROXY-2-OXOVALERATE LYASE PYRUVATE 4.1.3.- PLASMID HMG-COA LYASE-LIKE TRANSFERASE HOA 280 340 2.0E-27 T 12-10-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 TSC_c11570 0ff63743a10a88afe24fe2beed3ac51f 347 SUPERFAMILY SSF89000 292 340 1.96E-15 T 12-10-2018 TSC_c11570 0ff63743a10a88afe24fe2beed3ac51f 347 SUPERFAMILY SSF51569 8 280 1.19E-69 T 12-10-2018 TSC_c11570 0ff63743a10a88afe24fe2beed3ac51f 347 Gene3D G3DSA:3.20.20.70 11 272 5.1E-90 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c11570 0ff63743a10a88afe24fe2beed3ac51f 347 TIGRFAM TIGR03217 4OH_2_O_val_ald: 4-hydroxy-2-oxovalerate aldolase 11 340 1.1E-158 T 12-10-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 TSC_c11570 0ff63743a10a88afe24fe2beed3ac51f 347 Pfam PF00682 HMGL-like 13 268 8.7E-61 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TSC_c11570 0ff63743a10a88afe24fe2beed3ac51f 347 Pfam PF07836 DmpG-like communication domain 279 338 4.9E-27 T 12-10-2018 IPR012425 DmpG-like communication GO:0016833|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 TSC_c11570 0ff63743a10a88afe24fe2beed3ac51f 347 Hamap MF_01656 4-hydroxy-2-oxovalerate aldolase [mhpE]. 1 347 162.578 T 12-10-2018 IPR017629 4-hydroxy-2-oxovalerate aldolase GO:0008701|GO:0019439 KEGG: 00360+4.1.3.39|KEGG: 00362+4.1.3.39|KEGG: 00621+4.1.3.39|KEGG: 00622+4.1.3.39|MetaCyc: PWY-5162 TSC_c11570 0ff63743a10a88afe24fe2beed3ac51f 347 Gene3D G3DSA:1.10.8.60 280 344 2.1E-24 T 12-10-2018 TSC_c15650 c12dc7e6bdb3521c285a63b7562ec34b 450 Pfam PF01420 Type I restriction modification DNA specificity domain 241 412 6.3E-19 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 TSC_c15650 c12dc7e6bdb3521c285a63b7562ec34b 450 Pfam PF01420 Type I restriction modification DNA specificity domain 20 199 1.1E-11 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 TSC_c15650 c12dc7e6bdb3521c285a63b7562ec34b 450 SUPERFAMILY SSF116734 10 218 2.62E-37 T 12-10-2018 TSC_c15650 c12dc7e6bdb3521c285a63b7562ec34b 450 Gene3D G3DSA:3.90.220.20 3 218 1.5E-31 T 12-10-2018 TSC_c15650 c12dc7e6bdb3521c285a63b7562ec34b 450 Gene3D G3DSA:3.90.220.20 225 435 1.2E-42 T 12-10-2018 TSC_c15650 c12dc7e6bdb3521c285a63b7562ec34b 450 SUPERFAMILY SSF116734 234 440 7.36E-43 T 12-10-2018 TSC_c07380 18b0ef5bbee7325a8bc216f10bb8c1ec 582 SMART SM00116 145 190 1.2E-4 T 12-10-2018 IPR000644 CBS domain TSC_c07380 18b0ef5bbee7325a8bc216f10bb8c1ec 582 SMART SM00116 207 254 9.1E-10 T 12-10-2018 IPR000644 CBS domain TSC_c07380 18b0ef5bbee7325a8bc216f10bb8c1ec 582 SMART SM00100 8 124 6.2E-9 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain TSC_c07380 18b0ef5bbee7325a8bc216f10bb8c1ec 582 SUPERFAMILY SSF51206 4 116 6.55E-22 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like TSC_c07380 18b0ef5bbee7325a8bc216f10bb8c1ec 582 Pfam PF00027 Cyclic nucleotide-binding domain 28 108 4.5E-17 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain TSC_c07380 18b0ef5bbee7325a8bc216f10bb8c1ec 582 Gene3D G3DSA:2.60.120.10 4 126 6.2E-23 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TSC_c07380 18b0ef5bbee7325a8bc216f10bb8c1ec 582 Pfam PF00571 CBS domain 138 189 5.7E-9 T 12-10-2018 IPR000644 CBS domain TSC_c07380 18b0ef5bbee7325a8bc216f10bb8c1ec 582 Pfam PF00571 CBS domain 200 250 5.9E-11 T 12-10-2018 IPR000644 CBS domain TSC_c07380 18b0ef5bbee7325a8bc216f10bb8c1ec 582 SUPERFAMILY SSF54631 137 250 2.27E-28 T 12-10-2018 TSC_c07380 18b0ef5bbee7325a8bc216f10bb8c1ec 582 Pfam PF03445 Putative nucleotidyltransferase DUF294 275 406 1.4E-41 T 12-10-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 TSC_c07380 18b0ef5bbee7325a8bc216f10bb8c1ec 582 Gene3D G3DSA:3.10.580.10 134 257 6.2E-33 T 12-10-2018 TSC_c07380 18b0ef5bbee7325a8bc216f10bb8c1ec 582 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 442 579 5.7E-42 T 12-10-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding TSC_c23180 0893bdd592f2bf298c4b5180c5b598db 517 SUPERFAMILY SSF161098 14 250 8.32E-42 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c23180 0893bdd592f2bf298c4b5180c5b598db 517 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 79 242 8.0E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c23180 0893bdd592f2bf298c4b5180c5b598db 517 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 343 510 9.1E-17 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c23180 0893bdd592f2bf298c4b5180c5b598db 517 SUPERFAMILY SSF161098 277 513 2.06E-38 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c23180 0893bdd592f2bf298c4b5180c5b598db 517 Gene3D G3DSA:1.10.3720.10 13 256 3.0E-49 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c23180 0893bdd592f2bf298c4b5180c5b598db 517 Gene3D G3DSA:1.10.3720.10 278 516 6.7E-39 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c16250 65c7fc5bc37a47754e2bd3d74719b4d2 316 Gene3D G3DSA:3.40.50.300 111 260 8.7E-21 T 12-10-2018 TSC_c16250 65c7fc5bc37a47754e2bd3d74719b4d2 316 SMART SM00382 130 265 5.8E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c16250 65c7fc5bc37a47754e2bd3d74719b4d2 316 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 134 219 1.3E-7 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSC_c16250 65c7fc5bc37a47754e2bd3d74719b4d2 316 SUPERFAMILY SSF52540 38 250 2.82E-14 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c02060 2128661cb780e4296656a26a032156ce 511 PIRSF PIRSF006615 2 511 6.8E-193 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSC_c02060 2128661cb780e4296656a26a032156ce 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 303 319 4.9E-83 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSC_c02060 2128661cb780e4296656a26a032156ce 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 412 433 4.9E-83 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSC_c02060 2128661cb780e4296656a26a032156ce 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 389 406 4.9E-83 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSC_c02060 2128661cb780e4296656a26a032156ce 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 276 295 4.9E-83 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSC_c02060 2128661cb780e4296656a26a032156ce 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 159 179 4.9E-83 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSC_c02060 2128661cb780e4296656a26a032156ce 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 256 275 4.9E-83 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSC_c02060 2128661cb780e4296656a26a032156ce 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 239 255 4.9E-83 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSC_c02060 2128661cb780e4296656a26a032156ce 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 343 362 4.9E-83 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSC_c02060 2128661cb780e4296656a26a032156ce 511 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 457 475 4.9E-83 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSC_c02060 2128661cb780e4296656a26a032156ce 511 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 18 505 3.1E-115 T 12-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 TSC_c02060 2128661cb780e4296656a26a032156ce 511 SUPERFAMILY SSF55486 6 505 4.19E-113 T 12-10-2018 TSC_c02060 2128661cb780e4296656a26a032156ce 511 Gene3D G3DSA:1.10.1370.30 1 509 1.2E-211 T 12-10-2018 TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 Gene3D G3DSA:2.40.50.250 467 583 1.8E-110 T 12-10-2018 TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 SMART SM00838 384 468 0.0073 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 PRINTS PR00315 GTP-binding elongation factor signature 5 18 2.7E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 PRINTS PR00315 GTP-binding elongation factor signature 83 94 2.7E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 PRINTS PR00315 GTP-binding elongation factor signature 47 55 2.7E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 PRINTS PR00315 GTP-binding elongation factor signature 119 128 2.7E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 PRINTS PR00315 GTP-binding elongation factor signature 67 77 2.7E-15 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 Gene3D G3DSA:3.40.50.300 1 192 9.0E-61 T 12-10-2018 TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 132 1.5E-22 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 Gene3D G3DSA:3.30.70.240 380 466 1.8E-110 T 12-10-2018 TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 SUPERFAMILY SSF52540 3 194 4.73E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 3 583 5.1E-250 T 12-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 40 55 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 Pfam PF03144 Elongation factor Tu domain 2 212 281 1.0E-8 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 Gene3D G3DSA:2.40.30.10 194 291 2.4E-29 T 12-10-2018 TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 SUPERFAMILY SSF54980 385 497 1.04E-22 T 12-10-2018 IPR035647 EF-G domain III/V-like TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 Pfam PF00679 Elongation factor G C-terminus 384 459 1.7E-15 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 SUPERFAMILY SSF54980 294 378 6.23E-11 T 12-10-2018 IPR035647 EF-G domain III/V-like TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 SUPERFAMILY SSF50447 147 291 3.12E-26 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 Gene3D G3DSA:3.30.70.870 298 574 1.8E-110 T 12-10-2018 TSC_c24050 624f9c11a5e6ca62dde9d0af05efb5f8 587 Pfam PF00009 Elongation factor Tu GTP binding domain 2 190 5.7E-50 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c06430 e5e7638fbf87d2631f76636eca9d692e 207 Pfam PF01634 ATP phosphoribosyltransferase 53 201 6.3E-40 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 TSC_c06430 e5e7638fbf87d2631f76636eca9d692e 207 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 6 181 1.9E-50 T 12-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 TSC_c06430 e5e7638fbf87d2631f76636eca9d692e 207 Gene3D G3DSA:3.40.190.10 94 176 2.1E-66 T 12-10-2018 TSC_c06430 e5e7638fbf87d2631f76636eca9d692e 207 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 140 161 - T 12-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 TSC_c06430 e5e7638fbf87d2631f76636eca9d692e 207 SUPERFAMILY SSF53850 5 202 2.39E-56 T 12-10-2018 TSC_c06430 e5e7638fbf87d2631f76636eca9d692e 207 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 5 205 44.49 T 12-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 TSC_c06430 e5e7638fbf87d2631f76636eca9d692e 207 Gene3D G3DSA:3.40.190.10 7 198 2.1E-66 T 12-10-2018 TSC_c10740 d1e0bfa1179d96051199243f26a313aa 256 Pfam PF08241 Methyltransferase domain 48 142 1.1E-22 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSC_c10740 d1e0bfa1179d96051199243f26a313aa 256 SUPERFAMILY SSF53335 11 207 2.09E-44 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c10740 d1e0bfa1179d96051199243f26a313aa 256 Gene3D G3DSA:3.40.50.150 24 238 1.3E-56 T 12-10-2018 TSC_c22580 0368bef8468208d01b43f2176da71268 261 SUPERFAMILY SSF52096 15 261 4.98E-60 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSC_c22580 0368bef8468208d01b43f2176da71268 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 18 261 6.5E-38 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSC_c22580 0368bef8468208d01b43f2176da71268 261 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 106 126 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 TSC_c22580 0368bef8468208d01b43f2176da71268 261 Gene3D G3DSA:1.10.12.10 206 261 6.4E-25 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TSC_c22580 0368bef8468208d01b43f2176da71268 261 Gene3D G3DSA:3.90.226.10 1 205 8.9E-68 T 12-10-2018 TSC_c08970 ca597edeedb35dc9fb2dbe8e9a3fe451 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 378 1.1E-49 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSC_c08970 ca597edeedb35dc9fb2dbe8e9a3fe451 387 PIRSF PIRSF016578 13 370 2.8E-26 T 12-10-2018 TSC_c08970 ca597edeedb35dc9fb2dbe8e9a3fe451 387 Gene3D G3DSA:2.40.110.10 128 235 3.1E-31 T 12-10-2018 TSC_c08970 ca597edeedb35dc9fb2dbe8e9a3fe451 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 220 2.0E-20 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSC_c08970 ca597edeedb35dc9fb2dbe8e9a3fe451 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 130 142 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSC_c08970 ca597edeedb35dc9fb2dbe8e9a3fe451 387 Gene3D G3DSA:1.10.540.10 17 127 4.7E-25 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSC_c08970 ca597edeedb35dc9fb2dbe8e9a3fe451 387 SUPERFAMILY SSF47203 231 381 5.48E-53 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSC_c08970 ca597edeedb35dc9fb2dbe8e9a3fe451 387 Gene3D G3DSA:1.20.140.10 236 385 6.2E-53 T 12-10-2018 TSC_c08970 ca597edeedb35dc9fb2dbe8e9a3fe451 387 SUPERFAMILY SSF56645 20 228 3.53E-56 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSC_c08970 ca597edeedb35dc9fb2dbe8e9a3fe451 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 19 122 5.5E-20 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSC_c08970 ca597edeedb35dc9fb2dbe8e9a3fe451 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSC_c21630 d26bd0a05d324b9a7005b43df1bdc59e 468 SUPERFAMILY SSF55874 302 462 2.23E-46 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c21630 d26bd0a05d324b9a7005b43df1bdc59e 468 Pfam PF00512 His Kinase A (phospho-acceptor) domain 247 310 2.1E-19 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c21630 d26bd0a05d324b9a7005b43df1bdc59e 468 SUPERFAMILY SSF47384 229 311 1.88E-20 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSC_c21630 d26bd0a05d324b9a7005b43df1bdc59e 468 Gene3D G3DSA:1.10.287.130 197 311 7.7E-25 T 12-10-2018 TSC_c21630 d26bd0a05d324b9a7005b43df1bdc59e 468 SMART SM00388 246 312 1.7E-21 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c21630 d26bd0a05d324b9a7005b43df1bdc59e 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 401 2.7E-21 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c21630 d26bd0a05d324b9a7005b43df1bdc59e 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 459 2.7E-21 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c21630 d26bd0a05d324b9a7005b43df1bdc59e 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 2.7E-21 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c21630 d26bd0a05d324b9a7005b43df1bdc59e 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 415 2.7E-21 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c21630 d26bd0a05d324b9a7005b43df1bdc59e 468 Gene3D G3DSA:3.30.565.10 317 462 1.7E-46 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c21630 d26bd0a05d324b9a7005b43df1bdc59e 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 352 460 6.0E-32 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c21630 d26bd0a05d324b9a7005b43df1bdc59e 468 SMART SM00387 352 462 8.3E-45 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c22960 9425dcfb81faa66e444b19da366b2c01 180 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 21 4.0E-7 T 12-10-2018 TSC_c22960 9425dcfb81faa66e444b19da366b2c01 180 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 123 145 4.0E-7 T 12-10-2018 TSC_c22960 9425dcfb81faa66e444b19da366b2c01 180 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 45 156 2.5E-6 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSC_c22960 9425dcfb81faa66e444b19da366b2c01 180 Gene3D G3DSA:3.50.50.60 1 173 3.0E-67 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c22960 9425dcfb81faa66e444b19da366b2c01 180 SUPERFAMILY SSF51905 2 172 2.16E-30 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c22960 9425dcfb81faa66e444b19da366b2c01 180 Pfam PF01494 FAD binding domain 3 32 1.2E-7 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 TSC_c22960 9425dcfb81faa66e444b19da366b2c01 180 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 34 49 1.5E-14 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c22960 9425dcfb81faa66e444b19da366b2c01 180 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 1.5E-14 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c22960 9425dcfb81faa66e444b19da366b2c01 180 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 55 65 1.5E-14 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c00870 aaa3ad560c37eb98fd573c41c3be85a0 257 Gene3D G3DSA:3.40.1280.10 105 257 2.8E-55 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSC_c00870 aaa3ad560c37eb98fd573c41c3be85a0 257 Gene3D G3DSA:3.30.1330.30 1 97 1.3E-30 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like TSC_c00870 aaa3ad560c37eb98fd573c41c3be85a0 257 SMART SM00967 30 99 6.4E-4 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TSC_c00870 aaa3ad560c37eb98fd573c41c3be85a0 257 SUPERFAMILY SSF75217 103 254 1.05E-41 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases TSC_c00870 aaa3ad560c37eb98fd573c41c3be85a0 257 SUPERFAMILY SSF55315 1 96 4.94E-19 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like TSC_c00870 aaa3ad560c37eb98fd573c41c3be85a0 257 Pfam PF00588 SpoU rRNA Methylase family 110 248 5.2E-32 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TSC_c16620 661cd81e3c761bef1dd501607367bcad 164 Gene3D G3DSA:3.40.30.10 42 159 2.0E-7 T 12-10-2018 TSC_c16620 661cd81e3c761bef1dd501607367bcad 164 Pfam PF13098 Thioredoxin-like domain 47 149 1.8E-8 T 12-10-2018 IPR012336 Thioredoxin-like fold TSC_c16620 661cd81e3c761bef1dd501607367bcad 164 SUPERFAMILY SSF52833 23 154 6.88E-14 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TSC_c09020 f0e9342039c51e08ed8d9f33c413f904 234 SUPERFAMILY SSF52540 3 231 3.34E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c09020 f0e9342039c51e08ed8d9f33c413f904 234 Gene3D G3DSA:3.40.50.300 1 234 4.7E-59 T 12-10-2018 TSC_c09020 f0e9342039c51e08ed8d9f33c413f904 234 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c09020 f0e9342039c51e08ed8d9f33c413f904 234 Pfam PF00005 ABC transporter 20 162 2.1E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c09020 f0e9342039c51e08ed8d9f33c413f904 234 SMART SM00382 27 213 3.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c15370 c8152ca53c870fda05390d939d2c6637 224 SUPERFAMILY SSF161098 2 212 4.32E-49 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c15370 c8152ca53c870fda05390d939d2c6637 224 Gene3D G3DSA:1.10.3720.10 1 219 1.8E-57 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c15370 c8152ca53c870fda05390d939d2c6637 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 27 211 6.6E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c15370 c8152ca53c870fda05390d939d2c6637 224 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 10 214 1.5E-66 T 12-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 TSC_c10010 70f6d35caaa40da55a329bdfc18d4b1d 416 SUPERFAMILY SSF52540 2 411 6.19E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c10010 70f6d35caaa40da55a329bdfc18d4b1d 416 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 311 381 4.0E-6 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TSC_c10010 70f6d35caaa40da55a329bdfc18d4b1d 416 Pfam PF07724 AAA domain (Cdc48 subfamily) 186 305 9.7E-38 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSC_c10010 70f6d35caaa40da55a329bdfc18d4b1d 416 Gene3D G3DSA:1.10.8.10 109 219 4.6E-94 T 12-10-2018 TSC_c10010 70f6d35caaa40da55a329bdfc18d4b1d 416 Gene3D G3DSA:1.10.8.60 311 413 7.9E-31 T 12-10-2018 TSC_c10010 70f6d35caaa40da55a329bdfc18d4b1d 416 SMART SM00382 48 308 9.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c10010 70f6d35caaa40da55a329bdfc18d4b1d 416 Gene3D G3DSA:3.40.50.300 5 308 4.6E-94 T 12-10-2018 TSC_c10010 70f6d35caaa40da55a329bdfc18d4b1d 416 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 52 116 1.1E-6 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSC_c10010 70f6d35caaa40da55a329bdfc18d4b1d 416 SMART SM01086 311 404 4.3E-13 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TSC_c14130 18168bba9295cfa899e66c4876fc2ae6 516 Gene3D G3DSA:2.30.310.10 1 162 7.7E-20 T 12-10-2018 TSC_c14130 18168bba9295cfa899e66c4876fc2ae6 516 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 3 232 2.9E-29 T 12-10-2018 TSC_c14130 18168bba9295cfa899e66c4876fc2ae6 516 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 234 385 2.3E-21 T 12-10-2018 TSC_c14130 18168bba9295cfa899e66c4876fc2ae6 516 Pfam PF05670 Domain of unknown function (DUF814) 403 485 1.3E-25 T 12-10-2018 IPR008532 Domain of unknown function DUF814 TSC_c04300 782e73e3cea0a676e9529be5940e7e1c 265 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 263 3.1E-84 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 TSC_c04300 782e73e3cea0a676e9529be5940e7e1c 265 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 105 7.5E-27 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TSC_c04300 782e73e3cea0a676e9529be5940e7e1c 265 SUPERFAMILY SSF57716 213 263 1.54E-17 T 12-10-2018 TSC_c04300 782e73e3cea0a676e9529be5940e7e1c 265 SUPERFAMILY SSF81624 2 124 2.88E-33 T 12-10-2018 IPR035937 MutM-like, N-terminal TSC_c04300 782e73e3cea0a676e9529be5940e7e1c 265 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 122 211 1.2E-26 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TSC_c04300 782e73e3cea0a676e9529be5940e7e1c 265 ProSitePatterns PS01242 Zinc finger FPG-type signature. 239 263 - T 12-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 TSC_c04300 782e73e3cea0a676e9529be5940e7e1c 265 SMART SM00898 2 106 9.1E-36 T 12-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 TSC_c04300 782e73e3cea0a676e9529be5940e7e1c 265 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 264 40.256 T 12-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 TSC_c04300 782e73e3cea0a676e9529be5940e7e1c 265 SMART SM01232 122 214 4.4E-39 T 12-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 TSC_c04300 782e73e3cea0a676e9529be5940e7e1c 265 SUPERFAMILY SSF46946 122 211 2.21E-27 T 12-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 TSC_c04300 782e73e3cea0a676e9529be5940e7e1c 265 Pfam PF06827 Zinc finger found in FPG and IleRS 236 263 6.2E-12 T 12-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 TSC_c04300 782e73e3cea0a676e9529be5940e7e1c 265 Gene3D G3DSA:3.20.190.10 2 121 4.1E-41 T 12-10-2018 IPR035937 MutM-like, N-terminal TSC_c04300 782e73e3cea0a676e9529be5940e7e1c 265 Gene3D G3DSA:1.10.8.50 122 259 4.5E-51 T 12-10-2018 TSC_c15070 0aaa986ef9994e77f0c5dffbebb74a86 445 SUPERFAMILY SSF116726 136 225 9.16E-12 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSC_c15070 0aaa986ef9994e77f0c5dffbebb74a86 445 Gene3D G3DSA:3.30.70.1450 141 228 4.3E-13 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSC_c15070 0aaa986ef9994e77f0c5dffbebb74a86 445 SUPERFAMILY SSF51735 232 373 7.46E-35 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c15070 0aaa986ef9994e77f0c5dffbebb74a86 445 Gene3D G3DSA:3.40.50.720 233 346 3.8E-34 T 12-10-2018 TSC_c15070 0aaa986ef9994e77f0c5dffbebb74a86 445 Pfam PF02080 TrkA-C domain 155 225 3.8E-9 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TSC_c15070 0aaa986ef9994e77f0c5dffbebb74a86 445 Gene3D G3DSA:3.30.70.1450 351 441 4.4E-5 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSC_c15070 0aaa986ef9994e77f0c5dffbebb74a86 445 Gene3D G3DSA:3.40.50.720 1 140 3.7E-33 T 12-10-2018 TSC_c15070 0aaa986ef9994e77f0c5dffbebb74a86 445 PRINTS PR00335 TrkA potassium uptake protein signature 71 85 3.6E-14 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TSC_c15070 0aaa986ef9994e77f0c5dffbebb74a86 445 PRINTS PR00335 TrkA potassium uptake protein signature 58 68 3.6E-14 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TSC_c15070 0aaa986ef9994e77f0c5dffbebb74a86 445 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 3.6E-14 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TSC_c15070 0aaa986ef9994e77f0c5dffbebb74a86 445 PRINTS PR00335 TrkA potassium uptake protein signature 18 32 3.6E-14 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TSC_c15070 0aaa986ef9994e77f0c5dffbebb74a86 445 PRINTS PR00335 TrkA potassium uptake protein signature 47 57 3.6E-14 T 12-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 TSC_c15070 0aaa986ef9994e77f0c5dffbebb74a86 445 Pfam PF02254 TrkA-N domain 3 91 1.8E-23 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TSC_c15070 0aaa986ef9994e77f0c5dffbebb74a86 445 Pfam PF02254 TrkA-N domain 234 346 8.5E-28 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TSC_c15070 0aaa986ef9994e77f0c5dffbebb74a86 445 SUPERFAMILY SSF51735 1 150 4.86E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c21260 46bd41412bcfcb17388d59949440aac1 217 Gene3D G3DSA:3.40.50.2300 1 118 3.5E-33 T 12-10-2018 TSC_c21260 46bd41412bcfcb17388d59949440aac1 217 SUPERFAMILY SSF52172 1 125 2.56E-34 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c21260 46bd41412bcfcb17388d59949440aac1 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 214 3.3E-18 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c21260 46bd41412bcfcb17388d59949440aac1 217 Pfam PF00072 Response regulator receiver domain 3 109 5.7E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c21260 46bd41412bcfcb17388d59949440aac1 217 SMART SM00862 144 214 4.4E-23 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c21260 46bd41412bcfcb17388d59949440aac1 217 SMART SM00448 1 109 3.2E-34 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c21260 46bd41412bcfcb17388d59949440aac1 217 SUPERFAMILY SSF46894 120 215 7.65E-21 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSC_c21260 46bd41412bcfcb17388d59949440aac1 217 Gene3D G3DSA:1.10.10.10 121 216 2.3E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c17480 29c9a07e347873bc130b190cdbb9489c 225 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 4 217 8.1E-39 T 12-10-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 TSC_c17480 29c9a07e347873bc130b190cdbb9489c 225 Pfam PF02665 Nitrate reductase gamma subunit 4 219 9.2E-60 T 12-10-2018 IPR023234 NarG-like domain TSC_c17480 29c9a07e347873bc130b190cdbb9489c 225 SUPERFAMILY SSF103501 3 217 2.48E-50 T 12-10-2018 IPR036197 NarG-like superfamily TSC_c17480 29c9a07e347873bc130b190cdbb9489c 225 Gene3D G3DSA:1.20.950.20 2 212 1.4E-60 T 12-10-2018 TSC_c03990 747272ca7db3a2e0b3aa2b05390ee857 140 Pfam PF13470 PIN domain 3 114 4.2E-18 T 12-10-2018 IPR002716 PIN domain TSC_c03990 747272ca7db3a2e0b3aa2b05390ee857 140 SUPERFAMILY SSF88723 1 119 9.48E-13 T 12-10-2018 IPR029060 PIN-like domain superfamily TSC_c03990 747272ca7db3a2e0b3aa2b05390ee857 140 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 3 118 4.8E-16 T 12-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component TSC_c15080 1addfab04a08310d1b83d82403321244 434 SUPERFAMILY SSF102114 124 363 4.19E-49 T 12-10-2018 TSC_c15080 1addfab04a08310d1b83d82403321244 434 Pfam PF04055 Radical SAM superfamily 138 315 1.4E-27 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSC_c15080 1addfab04a08310d1b83d82403321244 434 Gene3D G3DSA:3.40.50.12160 2 119 7.0E-27 T 12-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily TSC_c15080 1addfab04a08310d1b83d82403321244 434 Pfam PF01938 TRAM domain 368 431 9.1E-5 T 12-10-2018 IPR002792 TRAM domain TSC_c15080 1addfab04a08310d1b83d82403321244 434 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 2 433 60.4 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 TSC_c15080 1addfab04a08310d1b83d82403321244 434 Pfam PF00919 Uncharacterized protein family UPF0004 3 85 1.8E-18 T 12-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 TSC_c15080 1addfab04a08310d1b83d82403321244 434 Gene3D G3DSA:2.40.50.140 372 434 2.8E-18 T 12-10-2018 TSC_c15080 1addfab04a08310d1b83d82403321244 434 SMART SM00729 132 357 2.3E-50 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSC_c15080 1addfab04a08310d1b83d82403321244 434 Gene3D G3DSA:3.80.30.20 130 371 2.4E-71 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TSC_c15080 1addfab04a08310d1b83d82403321244 434 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 431 7.8E-105 T 12-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 TSC_c15080 1addfab04a08310d1b83d82403321244 434 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 3 431 2.2E-169 T 12-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 TSC_c15080 1addfab04a08310d1b83d82403321244 434 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 136 156 - T 12-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 TSC_c21190 2537e74f7c4ef7948de036c47a612754 143 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 9 141 2.9E-60 T 12-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c21190 2537e74f7c4ef7948de036c47a612754 143 SUPERFAMILY SSF52161 8 142 4.97E-56 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TSC_c21190 2537e74f7c4ef7948de036c47a612754 143 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 28.797 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TSC_c21190 2537e74f7c4ef7948de036c47a612754 143 Pfam PF00572 Ribosomal protein L13 14 137 6.2E-56 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TSC_c21190 2537e74f7c4ef7948de036c47a612754 143 PIRSF PIRSF002181 1 143 1.3E-52 T 12-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 TSC_c21190 2537e74f7c4ef7948de036c47a612754 143 Gene3D G3DSA:3.90.1180.10 3 142 4.2E-64 T 12-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 TSC_c21190 2537e74f7c4ef7948de036c47a612754 143 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 12-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 TSC_c18880 398dc6384c0850192ac80bc293bd4693 226 Pfam PF03358 NADPH-dependent FMN reductase 13 171 9.0E-26 T 12-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 TSC_c18880 398dc6384c0850192ac80bc293bd4693 226 SUPERFAMILY SSF52218 10 202 3.87E-40 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TSC_c18880 398dc6384c0850192ac80bc293bd4693 226 Gene3D G3DSA:3.40.50.360 10 212 4.2E-34 T 12-10-2018 IPR029039 Flavoprotein-like superfamily TSC_c16930 74eea357c72d76079e586def58521cc9 367 Pfam PF00589 Phage integrase family 168 349 1.1E-21 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSC_c16930 74eea357c72d76079e586def58521cc9 367 Gene3D G3DSA:1.10.150.130 60 164 6.0E-20 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal TSC_c16930 74eea357c72d76079e586def58521cc9 367 SUPERFAMILY SSF56349 63 355 1.82E-64 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSC_c16930 74eea357c72d76079e586def58521cc9 367 Gene3D G3DSA:1.10.443.10 165 361 2.8E-49 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSC_c17730 84cab9fe6f4e85b5f2b745bb950ef3d4 231 Gene3D G3DSA:1.10.1060.10 101 230 3.8E-44 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSC_c17730 84cab9fe6f4e85b5f2b745bb950ef3d4 231 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 5 105 2.8E-30 T 12-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c17730 84cab9fe6f4e85b5f2b745bb950ef3d4 231 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 9 223 7.1E-72 T 12-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c17730 84cab9fe6f4e85b5f2b745bb950ef3d4 231 Pfam PF13183 4Fe-4S dicluster domain 140 213 2.6E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c17730 84cab9fe6f4e85b5f2b745bb950ef3d4 231 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 142 153 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c17730 84cab9fe6f4e85b5f2b745bb950ef3d4 231 SUPERFAMILY SSF54292 3 100 1.14E-27 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSC_c17730 84cab9fe6f4e85b5f2b745bb950ef3d4 231 Gene3D G3DSA:3.10.20.30 1 100 2.1E-29 T 12-10-2018 IPR012675 Beta-grasp domain superfamily TSC_c17730 84cab9fe6f4e85b5f2b745bb950ef3d4 231 SUPERFAMILY SSF46548 102 228 2.09E-30 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSC_c05520 d59bea489ca1a02e11e42b0f99d54c37 273 Gene3D G3DSA:1.10.12.10 215 273 4.7E-21 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TSC_c05520 d59bea489ca1a02e11e42b0f99d54c37 273 SUPERFAMILY SSF52096 10 272 3.78E-95 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSC_c05520 d59bea489ca1a02e11e42b0f99d54c37 273 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 116 136 - T 12-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 TSC_c05520 d59bea489ca1a02e11e42b0f99d54c37 273 Gene3D G3DSA:3.90.226.10 3 214 4.1E-76 T 12-10-2018 TSC_c05520 d59bea489ca1a02e11e42b0f99d54c37 273 Pfam PF00378 Enoyl-CoA hydratase/isomerase 25 272 7.4E-71 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSC_c03010 5cfe5ea5e4b95e5420e0741b2db81e69 606 Gene3D G3DSA:3.40.50.720 133 258 3.0E-36 T 12-10-2018 TSC_c03010 5cfe5ea5e4b95e5420e0741b2db81e69 606 SUPERFAMILY SSF51735 134 264 2.95E-20 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c03010 5cfe5ea5e4b95e5420e0741b2db81e69 606 Gene3D G3DSA:3.40.50.720 272 596 1.6E-117 T 12-10-2018 TSC_c03010 5cfe5ea5e4b95e5420e0741b2db81e69 606 SUPERFAMILY SSF51735 275 539 7.61E-64 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c03010 5cfe5ea5e4b95e5420e0741b2db81e69 606 Pfam PF13727 CoA-binding domain 55 232 1.6E-16 T 12-10-2018 TSC_c03010 5cfe5ea5e4b95e5420e0741b2db81e69 606 Pfam PF02719 Polysaccharide biosynthesis protein 277 561 3.1E-118 T 12-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain TSC_c22350 f6d7660680851f7756dc7bbb6e810949 105 ProSitePatterns PS00056 Ribosomal protein S17 signature. 54 66 - T 12-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22350 f6d7660680851f7756dc7bbb6e810949 105 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 3 73 2.3E-34 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22350 f6d7660680851f7756dc7bbb6e810949 105 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 3 74 8.0E-33 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22350 f6d7660680851f7756dc7bbb6e810949 105 Gene3D G3DSA:2.40.50.140 2 105 1.6E-46 T 12-10-2018 TSC_c22350 f6d7660680851f7756dc7bbb6e810949 105 Pfam PF00366 Ribosomal protein S17 8 74 8.8E-32 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22350 f6d7660680851f7756dc7bbb6e810949 105 SUPERFAMILY SSF50249 3 100 1.66E-32 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c22350 f6d7660680851f7756dc7bbb6e810949 105 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 3 78 24.189 T 12-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22350 f6d7660680851f7756dc7bbb6e810949 105 PRINTS PR00973 Ribosomal protein S17 family signature 64 71 5.1E-12 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22350 f6d7660680851f7756dc7bbb6e810949 105 PRINTS PR00973 Ribosomal protein S17 family signature 22 45 5.1E-12 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22350 f6d7660680851f7756dc7bbb6e810949 105 PRINTS PR00973 Ribosomal protein S17 family signature 54 64 5.1E-12 T 12-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c06790 292a2c8bbd9c94cbd0d728088b34608c 509 Gene3D G3DSA:1.10.3210.10 319 508 9.7E-39 T 12-10-2018 TSC_c06790 292a2c8bbd9c94cbd0d728088b34608c 509 PIRSF PIRSF001267 8 497 4.2E-79 T 12-10-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 TSC_c06790 292a2c8bbd9c94cbd0d728088b34608c 509 SUPERFAMILY SSF53067 18 137 6.95E-25 T 12-10-2018 TSC_c06790 292a2c8bbd9c94cbd0d728088b34608c 509 SUPERFAMILY SSF109604 320 506 7.33E-44 T 12-10-2018 TSC_c06790 292a2c8bbd9c94cbd0d728088b34608c 509 Pfam PF01966 HD domain 337 422 6.1E-5 T 12-10-2018 IPR006674 HD domain TSC_c06790 292a2c8bbd9c94cbd0d728088b34608c 509 Pfam PF02541 Ppx/GppA phosphatase family 31 312 1.1E-42 T 12-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 TSC_c06790 292a2c8bbd9c94cbd0d728088b34608c 509 SUPERFAMILY SSF53067 140 311 2.07E-35 T 12-10-2018 TSC_c06790 292a2c8bbd9c94cbd0d728088b34608c 509 Gene3D G3DSA:3.30.420.150 138 316 7.8E-38 T 12-10-2018 TSC_c06790 292a2c8bbd9c94cbd0d728088b34608c 509 Gene3D G3DSA:3.30.420.40 5 137 1.4E-29 T 12-10-2018 TSC_c18970 02b36ed1456c33611c8117df670d5eb4 577 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 577 2.1E-244 T 12-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c18970 02b36ed1456c33611c8117df670d5eb4 577 SUPERFAMILY SSF56425 232 350 5.23E-42 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c18970 02b36ed1456c33611c8117df670d5eb4 577 Gene3D G3DSA:3.90.700.10 242 345 1.4E-161 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c18970 02b36ed1456c33611c8117df670d5eb4 577 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 3 577 7.1E-285 T 12-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c18970 02b36ed1456c33611c8117df670d5eb4 577 Pfam PF02910 Fumarate reductase flavoprotein C-term 451 577 3.6E-43 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c18970 02b36ed1456c33611c8117df670d5eb4 577 PIRSF PIRSF000171 1 570 1.7E-49 T 12-10-2018 TSC_c18970 02b36ed1456c33611c8117df670d5eb4 577 SUPERFAMILY SSF51905 3 420 6.02E-76 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c18970 02b36ed1456c33611c8117df670d5eb4 577 Gene3D G3DSA:1.20.58.100 423 538 5.2E-37 T 12-10-2018 TSC_c18970 02b36ed1456c33611c8117df670d5eb4 577 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.2E-7 T 12-10-2018 TSC_c18970 02b36ed1456c33611c8117df670d5eb4 577 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 360 382 1.2E-7 T 12-10-2018 TSC_c18970 02b36ed1456c33611c8117df670d5eb4 577 Gene3D G3DSA:3.50.50.60 7 408 1.4E-161 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c18970 02b36ed1456c33611c8117df670d5eb4 577 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 12-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c18970 02b36ed1456c33611c8117df670d5eb4 577 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 3.1E-6 T 12-10-2018 TSC_c18970 02b36ed1456c33611c8117df670d5eb4 577 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 375 382 3.1E-6 T 12-10-2018 TSC_c18970 02b36ed1456c33611c8117df670d5eb4 577 SUPERFAMILY SSF46977 443 577 6.28E-52 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c18970 02b36ed1456c33611c8117df670d5eb4 577 Gene3D G3DSA:4.10.80.40 539 573 6.4E-8 T 12-10-2018 TSC_c18970 02b36ed1456c33611c8117df670d5eb4 577 Pfam PF00890 FAD binding domain 7 397 5.4E-114 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c17070 6b746027fd5e0105056ebfda9ddafe45 145 SUPERFAMILY SSF55961 1 141 1.03E-28 T 12-10-2018 TSC_c17070 6b746027fd5e0105056ebfda9ddafe45 145 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 2 142 2.2E-18 T 12-10-2018 IPR019587 Polyketide cyclase/dehydrase TSC_c17070 6b746027fd5e0105056ebfda9ddafe45 145 Gene3D G3DSA:3.30.530.20 1 145 2.8E-42 T 12-10-2018 IPR023393 START-like domain superfamily TSC_c11680 bd7407ea16b8f3840b583f0144215c49 337 Gene3D G3DSA:1.10.1610.10 13 333 5.8E-135 T 12-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TSC_c11680 bd7407ea16b8f3840b583f0144215c49 337 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 1 335 34.473 T 12-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TSC_c11680 bd7407ea16b8f3840b583f0144215c49 337 SUPERFAMILY SSF52733 5 335 4.19E-113 T 12-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TSC_c11680 bd7407ea16b8f3840b583f0144215c49 337 Gene3D G3DSA:3.40.50.10210 45 317 5.8E-135 T 12-10-2018 TSC_c11680 bd7407ea16b8f3840b583f0144215c49 337 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 4 333 4.1E-128 T 12-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TSC_c11680 bd7407ea16b8f3840b583f0144215c49 337 Pfam PF02277 Phosphoribosyltransferase 5 333 2.1E-127 T 12-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 TSC_c05700 f0a886d03d4c490f0f826148a6a280e9 64 Pfam PF00825 Ribonuclease P 1 59 1.3E-16 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TSC_c05700 f0a886d03d4c490f0f826148a6a280e9 64 Gene3D G3DSA:3.30.230.10 1 64 1.7E-17 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSC_c05700 f0a886d03d4c490f0f826148a6a280e9 64 SUPERFAMILY SSF54211 1 62 2.17E-16 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c05700 f0a886d03d4c490f0f826148a6a280e9 64 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 2 60 7.6E-12 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TSC_c05700 f0a886d03d4c490f0f826148a6a280e9 64 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 5 54 2.0E-5 T 12-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 TSC_c05700 f0a886d03d4c490f0f826148a6a280e9 64 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 6 20 - T 12-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 TSC_c17800 5128f6ddb210bfbeba77238bc555994f 105 SUPERFAMILY SSF52540 1 52 4.65E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c17800 5128f6ddb210bfbeba77238bc555994f 105 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 1 50 6.6E-23 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 TSC_c17800 5128f6ddb210bfbeba77238bc555994f 105 Gene3D G3DSA:3.40.50.300 1 58 1.2E-10 T 12-10-2018 TSC_c14520 a07bca780b959414e5dea0e2b78b5a84 446 Gene3D G3DSA:3.90.190.20 300 445 6.5E-40 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSC_c14520 a07bca780b959414e5dea0e2b78b5a84 446 SUPERFAMILY SSF51984 1 84 6.41E-19 T 12-10-2018 TSC_c14520 a07bca780b959414e5dea0e2b78b5a84 446 SUPERFAMILY SSF53623 84 299 4.24E-45 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSC_c14520 a07bca780b959414e5dea0e2b78b5a84 446 Pfam PF01225 Mur ligase family, catalytic domain 4 97 8.1E-19 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TSC_c14520 a07bca780b959414e5dea0e2b78b5a84 446 Gene3D G3DSA:3.40.50.720 2 86 6.3E-20 T 12-10-2018 TSC_c14520 a07bca780b959414e5dea0e2b78b5a84 446 Pfam PF02875 Mur ligase family, glutamate ligase domain 302 382 1.3E-13 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TSC_c14520 a07bca780b959414e5dea0e2b78b5a84 446 SUPERFAMILY SSF53244 301 443 2.56E-33 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSC_c14520 a07bca780b959414e5dea0e2b78b5a84 446 Pfam PF08245 Mur ligase middle domain 103 282 9.6E-15 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TSC_c14520 a07bca780b959414e5dea0e2b78b5a84 446 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 446 30.733 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSC_c14520 a07bca780b959414e5dea0e2b78b5a84 446 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 4 440 3.3E-104 T 12-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSC_c14520 a07bca780b959414e5dea0e2b78b5a84 446 Gene3D G3DSA:3.40.1190.10 87 299 2.7E-50 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSC_c17540 31bf5db7a5d1b85ccb356165f9adf5b4 217 Gene3D G3DSA:2.60.120.10 2 142 5.1E-42 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TSC_c17540 31bf5db7a5d1b85ccb356165f9adf5b4 217 Pfam PF13545 Crp-like helix-turn-helix domain 148 214 1.1E-14 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSC_c17540 31bf5db7a5d1b85ccb356165f9adf5b4 217 Gene3D G3DSA:1.10.10.10 143 216 6.6E-18 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c17540 31bf5db7a5d1b85ccb356165f9adf5b4 217 SMART SM00100 8 128 1.9E-23 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain TSC_c17540 31bf5db7a5d1b85ccb356165f9adf5b4 217 Pfam PF00027 Cyclic nucleotide-binding domain 27 114 2.1E-21 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain TSC_c17540 31bf5db7a5d1b85ccb356165f9adf5b4 217 SUPERFAMILY SSF51206 3 143 6.15E-36 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like TSC_c17540 31bf5db7a5d1b85ccb356165f9adf5b4 217 SUPERFAMILY SSF46785 146 216 1.03E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c17540 31bf5db7a5d1b85ccb356165f9adf5b4 217 SMART SM00419 161 208 2.7E-6 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSC_c07110 ffa8e11f1c4638f02516cde6d71a19a5 745 SUPERFAMILY SSF52540 66 387 7.19E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c07110 ffa8e11f1c4638f02516cde6d71a19a5 745 Pfam PF00270 DEAD/DEAH box helicase 59 225 3.1E-23 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSC_c07110 ffa8e11f1c4638f02516cde6d71a19a5 745 Gene3D G3DSA:3.40.50.300 264 402 8.2E-26 T 12-10-2018 TSC_c07110 ffa8e11f1c4638f02516cde6d71a19a5 745 Pfam PF00271 Helicase conserved C-terminal domain 282 378 3.0E-16 T 12-10-2018 IPR001650 Helicase, C-terminal TSC_c07110 ffa8e11f1c4638f02516cde6d71a19a5 745 SMART SM00490 300 379 1.5E-17 T 12-10-2018 IPR001650 Helicase, C-terminal TSC_c07110 ffa8e11f1c4638f02516cde6d71a19a5 745 Pfam PF09369 Domain of unknown function (DUF1998) 628 711 8.0E-21 T 12-10-2018 IPR018973 DEAD/DEAH-box helicase, putative TSC_c07110 ffa8e11f1c4638f02516cde6d71a19a5 745 SMART SM00487 53 254 5.8E-29 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSC_c07110 ffa8e11f1c4638f02516cde6d71a19a5 745 Gene3D G3DSA:3.40.50.300 49 241 1.7E-37 T 12-10-2018 TSC_c09970 54d86d466a0534ee9742c5429614a704 464 SUPERFAMILY SSF52540 41 376 1.72E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c09970 54d86d466a0534ee9742c5429614a704 464 Gene3D G3DSA:3.40.50.300 39 249 8.0E-27 T 12-10-2018 TSC_c09970 54d86d466a0534ee9742c5429614a704 464 Pfam PF00158 Sigma-54 interaction domain 168 225 1.2E-4 T 12-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 TSC_c04930 5fc3db176f01b3accab37298a30b6c84 147 Pfam PF01220 Dehydroquinase class II 2 138 7.3E-55 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TSC_c04930 5fc3db176f01b3accab37298a30b6c84 147 PIRSF PIRSF001399 1 144 1.3E-58 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TSC_c04930 5fc3db176f01b3accab37298a30b6c84 147 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 147 64.395 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TSC_c04930 5fc3db176f01b3accab37298a30b6c84 147 ProSitePatterns PS01029 Dehydroquinase class II signature. 5 22 - T 12-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TSC_c04930 5fc3db176f01b3accab37298a30b6c84 147 SUPERFAMILY SSF52304 2 142 1.44E-57 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TSC_c04930 5fc3db176f01b3accab37298a30b6c84 147 Gene3D G3DSA:3.40.50.9100 1 146 3.4E-63 T 12-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TSC_c04930 5fc3db176f01b3accab37298a30b6c84 147 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 16 132 7.0E-46 T 12-10-2018 TSC_c04930 5fc3db176f01b3accab37298a30b6c84 147 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 1 141 4.0E-58 T 12-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 TSC_c21820 af5f4b5b1bf805860391c57e8d9f9fe1 237 Gene3D G3DSA:1.10.150.400 21 106 2.9E-33 T 12-10-2018 TSC_c21820 af5f4b5b1bf805860391c57e8d9f9fe1 237 Gene3D G3DSA:3.40.50.1000 4 204 2.9E-33 T 12-10-2018 IPR023214 HAD superfamily TSC_c21820 af5f4b5b1bf805860391c57e8d9f9fe1 237 SUPERFAMILY SSF56784 2 236 8.1E-32 T 12-10-2018 IPR036412 HAD-like superfamily TSC_c21820 af5f4b5b1bf805860391c57e8d9f9fe1 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 152 168 8.0E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c21820 af5f4b5b1bf805860391c57e8d9f9fe1 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 170 190 8.0E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c21820 af5f4b5b1bf805860391c57e8d9f9fe1 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 8.0E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c21820 af5f4b5b1bf805860391c57e8d9f9fe1 237 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 123 201 2.3E-8 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c21820 af5f4b5b1bf805860391c57e8d9f9fe1 237 Pfam PF13419 Haloacid dehalogenase-like hydrolase 82 204 2.3E-12 T 12-10-2018 TSC_c10190 f24cc19358c7f624bb070783d669f6d8 501 Gene3D G3DSA:3.40.50.300 11 243 5.8E-60 T 12-10-2018 TSC_c10190 f24cc19358c7f624bb070783d669f6d8 501 Gene3D G3DSA:3.40.50.300 261 496 3.8E-35 T 12-10-2018 TSC_c10190 f24cc19358c7f624bb070783d669f6d8 501 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c10190 f24cc19358c7f624bb070783d669f6d8 501 SUPERFAMILY SSF52540 13 230 1.11E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c10190 f24cc19358c7f624bb070783d669f6d8 501 SUPERFAMILY SSF52540 262 479 1.26E-37 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c10190 f24cc19358c7f624bb070783d669f6d8 501 SMART SM00382 38 224 7.8E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c10190 f24cc19358c7f624bb070783d669f6d8 501 Pfam PF00005 ABC transporter 278 424 2.6E-16 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c10190 f24cc19358c7f624bb070783d669f6d8 501 Pfam PF00005 ABC transporter 31 176 7.3E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c04810 eb7a3729ce4dd0356cedf17d2b8442d6 494 SUPERFAMILY SSF51412 5 485 6.67E-128 T 12-10-2018 TSC_c04810 eb7a3729ce4dd0356cedf17d2b8442d6 494 Gene3D G3DSA:3.20.20.70 1 494 4.0E-221 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c04810 eb7a3729ce4dd0356cedf17d2b8442d6 494 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 481 5.9E-163 T 12-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 TSC_c04810 eb7a3729ce4dd0356cedf17d2b8442d6 494 Pfam PF00571 CBS domain 95 142 5.3E-13 T 12-10-2018 IPR000644 CBS domain TSC_c04810 eb7a3729ce4dd0356cedf17d2b8442d6 494 Pfam PF00571 CBS domain 151 206 4.4E-12 T 12-10-2018 IPR000644 CBS domain TSC_c04810 eb7a3729ce4dd0356cedf17d2b8442d6 494 SUPERFAMILY SSF54631 69 205 1.64E-31 T 12-10-2018 TSC_c04810 eb7a3729ce4dd0356cedf17d2b8442d6 494 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 462 2.3E-188 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TSC_c04810 eb7a3729ce4dd0356cedf17d2b8442d6 494 SMART SM00116 160 208 8.0E-12 T 12-10-2018 IPR000644 CBS domain TSC_c04810 eb7a3729ce4dd0356cedf17d2b8442d6 494 SMART SM00116 98 146 2.5E-13 T 12-10-2018 IPR000644 CBS domain TSC_c04810 eb7a3729ce4dd0356cedf17d2b8442d6 494 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 494 85.344 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TSC_c04810 eb7a3729ce4dd0356cedf17d2b8442d6 494 SMART SM01240 9 481 0.0 T 12-10-2018 TSC_c04810 eb7a3729ce4dd0356cedf17d2b8442d6 494 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 298 310 - T 12-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 TSC_c04810 eb7a3729ce4dd0356cedf17d2b8442d6 494 PIRSF PIRSF000130 1 494 4.1E-209 T 12-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 TSC_c16410 33d3b5606b8576e71ca643ba11e6da53 200 Pfam PF05857 TraX protein 2 98 2.5E-18 T 12-10-2018 IPR008875 TraX TSC_c06650 903cfa72c299dc1fe7a18b067977ea05 391 Gene3D G3DSA:1.10.150.130 64 184 5.7E-17 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal TSC_c06650 903cfa72c299dc1fe7a18b067977ea05 391 Gene3D G3DSA:1.10.443.10 185 382 4.2E-50 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSC_c06650 903cfa72c299dc1fe7a18b067977ea05 391 SUPERFAMILY SSF56349 70 373 9.12E-63 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSC_c06650 903cfa72c299dc1fe7a18b067977ea05 391 Pfam PF00589 Phage integrase family 187 368 5.6E-30 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSC_c03500 578dcb0e67cd4a61fb8c8dc7099a86be 203 Pfam PF07849 Protein of unknown function (DUF1641) 144 180 3.5E-14 T 12-10-2018 IPR012440 Protein of unknown function DUF1641 TSC_c12190 2b3ae5e02b8fc8c7e6f1702842f33cf1 669 Gene3D G3DSA:3.10.129.10 517 668 1.4E-46 T 12-10-2018 TSC_c12190 2b3ae5e02b8fc8c7e6f1702842f33cf1 669 Pfam PF00171 Aldehyde dehydrogenase family 16 444 9.4E-60 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSC_c12190 2b3ae5e02b8fc8c7e6f1702842f33cf1 669 Gene3D G3DSA:3.40.605.10 9 476 1.5E-129 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSC_c12190 2b3ae5e02b8fc8c7e6f1702842f33cf1 669 TIGRFAM TIGR02278 PaaN-DH: phenylacetic acid degradation protein paaN 3 660 0.0 T 12-10-2018 IPR011966 Phenylacetic acid degradation protein PaaN KEGG: 00360+3.3.2.12+1.2.1.91 TSC_c12190 2b3ae5e02b8fc8c7e6f1702842f33cf1 669 SUPERFAMILY SSF54637 517 662 7.02E-41 T 12-10-2018 IPR029069 HotDog domain superfamily TSC_c12190 2b3ae5e02b8fc8c7e6f1702842f33cf1 669 SUPERFAMILY SSF53720 3 486 9.56E-76 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSC_c12190 2b3ae5e02b8fc8c7e6f1702842f33cf1 669 Gene3D G3DSA:3.40.309.10 257 464 1.5E-129 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSC_c12190 2b3ae5e02b8fc8c7e6f1702842f33cf1 669 Pfam PF01575 MaoC like domain 530 639 1.6E-27 T 12-10-2018 IPR002539 MaoC-like dehydratase domain TSC_c17460 c00d45553526d14b92d42ed8fb101665 443 Gene3D G3DSA:1.20.1250.20 234 442 3.4E-62 T 12-10-2018 TSC_c17460 c00d45553526d14b92d42ed8fb101665 443 Pfam PF07690 Major Facilitator Superfamily 40 335 9.3E-10 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c17460 c00d45553526d14b92d42ed8fb101665 443 TIGRFAM TIGR00886 2A0108: nitrite transporter 28 394 2.7E-99 T 12-10-2018 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 TSC_c17460 c00d45553526d14b92d42ed8fb101665 443 Gene3D G3DSA:1.20.1250.20 2 233 7.0E-66 T 12-10-2018 TSC_c17460 c00d45553526d14b92d42ed8fb101665 443 SUPERFAMILY SSF103473 10 434 1.57E-43 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c07930 46ed187fd3570058368fca888460ea99 976 Pfam PF13558 Putative exonuclease SbcCD, C subunit 877 936 3.8E-10 T 12-10-2018 TSC_c07930 46ed187fd3570058368fca888460ea99 976 Gene3D G3DSA:3.40.50.300 760 968 3.2E-23 T 12-10-2018 TSC_c07930 46ed187fd3570058368fca888460ea99 976 Pfam PF13476 AAA domain 5 230 2.8E-21 T 12-10-2018 IPR038729 Rad50/SbcC-type AAA domain TSC_c07930 46ed187fd3570058368fca888460ea99 976 SUPERFAMILY SSF52540 5 964 2.74E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c07930 46ed187fd3570058368fca888460ea99 976 Gene3D G3DSA:3.40.50.300 2 258 1.6E-45 T 12-10-2018 TSC_c00480 473bc9953f023bf55d0664f7684d4cc0 226 Gene3D G3DSA:3.40.50.300 6 224 3.4E-56 T 12-10-2018 TSC_c00480 473bc9953f023bf55d0664f7684d4cc0 226 Pfam PF00005 ABC transporter 23 149 2.5E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c00480 473bc9953f023bf55d0664f7684d4cc0 226 ProSitePatterns PS00211 ABC transporters family signature. 121 135 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c00480 473bc9953f023bf55d0664f7684d4cc0 226 SUPERFAMILY SSF52540 3 211 9.29E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c00480 473bc9953f023bf55d0664f7684d4cc0 226 PRINTS PR01868 ABC transporter family E signature 6 26 6.3E-7 T 12-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TSC_c00480 473bc9953f023bf55d0664f7684d4cc0 226 PRINTS PR01868 ABC transporter family E signature 33 58 6.3E-7 T 12-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 TSC_c00480 473bc9953f023bf55d0664f7684d4cc0 226 SMART SM00382 28 196 3.7E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c05460 1b42e72155feb673589b3784544d7392 232 SUPERFAMILY SSF46955 127 214 8.7E-19 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TSC_c05460 1b42e72155feb673589b3784544d7392 232 SMART SM00422 8 77 2.1E-25 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSC_c05460 1b42e72155feb673589b3784544d7392 232 SMART SM00422 127 196 2.1E-25 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSC_c05460 1b42e72155feb673589b3784544d7392 232 Gene3D G3DSA:1.10.1660.10 118 224 5.3E-22 T 12-10-2018 TSC_c05460 1b42e72155feb673589b3784544d7392 232 Gene3D G3DSA:1.10.1660.10 1 109 8.0E-23 T 12-10-2018 TSC_c05460 1b42e72155feb673589b3784544d7392 232 Pfam PF13411 MerR HTH family regulatory protein 127 194 2.7E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSC_c05460 1b42e72155feb673589b3784544d7392 232 Pfam PF13411 MerR HTH family regulatory protein 8 75 2.7E-18 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSC_c05460 1b42e72155feb673589b3784544d7392 232 SUPERFAMILY SSF46955 8 100 2.29E-19 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TSC_c10530 e12a19ece6fd0e3138746e56b726cf66 445 PIRSF PIRSF006444 1 445 2.5E-185 T 12-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 TSC_c10530 e12a19ece6fd0e3138746e56b726cf66 445 Pfam PF00501 AMP-binding enzyme 77 284 1.0E-13 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSC_c10530 e12a19ece6fd0e3138746e56b726cf66 445 SUPERFAMILY SSF56801 30 439 3.14E-59 T 12-10-2018 TSC_c10530 e12a19ece6fd0e3138746e56b726cf66 445 Gene3D G3DSA:3.30.300.30 326 445 5.4E-32 T 12-10-2018 TSC_c10530 e12a19ece6fd0e3138746e56b726cf66 445 Pfam PF14535 AMP-binding enzyme C-terminal domain 334 443 5.7E-31 T 12-10-2018 IPR028154 AMP-dependent ligase, C-terminal TSC_c10530 e12a19ece6fd0e3138746e56b726cf66 445 Gene3D G3DSA:3.40.50.12780 1 325 1.2E-126 T 12-10-2018 TSC_c13330 cb3fea9d56790033e828fb563b8c258d 422 Gene3D G3DSA:3.30.930.10 104 421 9.5E-110 T 12-10-2018 TSC_c13330 cb3fea9d56790033e828fb563b8c258d 422 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 413 1.5E-117 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSC_c13330 cb3fea9d56790033e828fb563b8c258d 422 PRINTS PR00981 Seryl-tRNA synthetase signature 259 271 5.7E-26 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSC_c13330 cb3fea9d56790033e828fb563b8c258d 422 PRINTS PR00981 Seryl-tRNA synthetase signature 271 284 5.7E-26 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSC_c13330 cb3fea9d56790033e828fb563b8c258d 422 PRINTS PR00981 Seryl-tRNA synthetase signature 330 346 5.7E-26 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSC_c13330 cb3fea9d56790033e828fb563b8c258d 422 PRINTS PR00981 Seryl-tRNA synthetase signature 313 326 5.7E-26 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSC_c13330 cb3fea9d56790033e828fb563b8c258d 422 PRINTS PR00981 Seryl-tRNA synthetase signature 348 364 5.7E-26 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSC_c13330 cb3fea9d56790033e828fb563b8c258d 422 PIRSF PIRSF001529 1 420 7.4E-123 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSC_c13330 cb3fea9d56790033e828fb563b8c258d 422 Gene3D G3DSA:1.10.287.40 1 49 1.8E-18 T 12-10-2018 TSC_c13330 cb3fea9d56790033e828fb563b8c258d 422 Gene3D G3DSA:1.10.287.40 55 102 4.0E-8 T 12-10-2018 TSC_c13330 cb3fea9d56790033e828fb563b8c258d 422 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 102 3.3E-21 T 12-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 TSC_c13330 cb3fea9d56790033e828fb563b8c258d 422 SUPERFAMILY SSF55681 114 420 1.05E-81 T 12-10-2018 TSC_c13330 cb3fea9d56790033e828fb563b8c258d 422 SUPERFAMILY SSF46589 1 110 5.07E-23 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TSC_c13330 cb3fea9d56790033e828fb563b8c258d 422 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 418 35.963 T 12-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 TSC_c13330 cb3fea9d56790033e828fb563b8c258d 422 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 219 396 3.0E-25 T 12-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 PIRSF PIRSF005499 8 713 9.2E-294 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 258 333 4.4E-7 T 12-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 Pfam PF00575 S1 RNA binding domain 631 699 1.1E-17 T 12-10-2018 IPR003029 S1 domain GO:0003676 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 Gene3D G3DSA:3.30.230.70 3 235 5.1E-84 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 SUPERFAMILY SSF55666 463 561 7.07E-28 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 18 702 6.3E-300 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 Gene3D G3DSA:3.30.230.70 245 562 6.6E-116 T 12-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 10 705 30.033 T 12-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 SUPERFAMILY SSF54211 306 500 1.82E-51 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 Pfam PF01138 3' exoribonuclease family, domain 1 336 469 3.4E-25 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 Pfam PF01138 3' exoribonuclease family, domain 1 21 150 3.9E-21 T 12-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 SMART SM00316 632 702 1.0E-26 T 12-10-2018 IPR022967 RNA-binding domain, S1 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 SMART SM00322 565 629 4.4E-13 T 12-10-2018 IPR004087 K Homology domain GO:0003676 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 SUPERFAMILY SSF55666 151 242 7.72E-31 T 12-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 Pfam PF03725 3' exoribonuclease family, domain 2 472 541 8.7E-7 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 Pfam PF03725 3' exoribonuclease family, domain 2 153 216 2.4E-19 T 12-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 SUPERFAMILY SSF54211 11 150 3.04E-46 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 SUPERFAMILY SSF50249 619 699 3.14E-21 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 SUPERFAMILY SSF54791 565 641 2.4E-14 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 Pfam PF00013 KH domain 570 626 7.9E-12 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 Gene3D G3DSA:2.40.50.140 634 704 5.5E-26 T 12-10-2018 TSC_c09640 77b3c299d22951bbfb4966b1d369d444 714 Gene3D G3DSA:3.30.1370.10 563 633 1.4E-17 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TSC_c14230 9ca29bf45041f2d4b55fed735f650117 210 ProDom PD037531 MEMBRANE HYDROGENASE SUBUNIT COMPONENT HYDROGENASE-4 E OXIDOREDUCTASE PRECURSOR SIGNAL 1.-.-.- 8 173 1.0E-16 T 12-10-2018 TSC_c01960 1713bcb87cefbffe7c4960bee18164d3 288 Gene3D G3DSA:3.60.110.10 2 267 3.8E-64 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSC_c01960 1713bcb87cefbffe7c4960bee18164d3 288 Pfam PF00795 Carbon-nitrogen hydrolase 5 260 4.8E-30 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TSC_c01960 1713bcb87cefbffe7c4960bee18164d3 288 SUPERFAMILY SSF56317 3 267 3.01E-57 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSC_c11510 f944d6f9803a9e727ddfb9beda64374f 287 Pfam PF02653 Branched-chain amino acid transport system / permease component 9 274 8.1E-39 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSC_c12770 44e0a02512aac1ede21962dcc05170bb 481 Pfam PF07969 Amidohydrolase family 33 479 9.8E-57 T 12-10-2018 IPR013108 Amidohydrolase 3 TSC_c12770 44e0a02512aac1ede21962dcc05170bb 481 Gene3D G3DSA:3.10.310.70 58 168 3.5E-85 T 12-10-2018 TSC_c12770 44e0a02512aac1ede21962dcc05170bb 481 Gene3D G3DSA:2.30.40.10 33 457 3.5E-85 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSC_c12770 44e0a02512aac1ede21962dcc05170bb 481 SUPERFAMILY SSF51556 38 433 1.87E-27 T 12-10-2018 IPR032466 Metal-dependent hydrolase TSC_c12770 44e0a02512aac1ede21962dcc05170bb 481 Gene3D G3DSA:3.20.20.140 39 442 3.5E-85 T 12-10-2018 TSC_c02660 fe3305984c9669befa8e09aac8de0aff 197 SUPERFAMILY SSF53041 54 182 1.57E-18 T 12-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 TSC_c02660 fe3305984c9669befa8e09aac8de0aff 197 Gene3D G3DSA:3.40.50.1390 51 149 9.3E-19 T 12-10-2018 TSC_c02660 fe3305984c9669befa8e09aac8de0aff 197 SMART SM00857 54 179 3.6E-16 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TSC_c02660 fe3305984c9669befa8e09aac8de0aff 197 Pfam PF00239 Resolvase, N terminal domain 54 180 3.5E-19 T 12-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 TSC_c04500 7f6a1f75dfb025b746fbbb6f0c90ff9e 695 Gene3D G3DSA:3.40.50.300 2 138 2.5E-17 T 12-10-2018 TSC_c04500 7f6a1f75dfb025b746fbbb6f0c90ff9e 695 Gene3D G3DSA:3.40.50.300 163 376 2.9E-42 T 12-10-2018 TSC_c04500 7f6a1f75dfb025b746fbbb6f0c90ff9e 695 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 562 667 2.1E-9 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TSC_c04500 7f6a1f75dfb025b746fbbb6f0c90ff9e 695 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 619 637 2.0E-8 T 12-10-2018 TSC_c04500 7f6a1f75dfb025b746fbbb6f0c90ff9e 695 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 559 578 2.0E-8 T 12-10-2018 TSC_c04500 7f6a1f75dfb025b746fbbb6f0c90ff9e 695 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 589 608 2.0E-8 T 12-10-2018 TSC_c04500 7f6a1f75dfb025b746fbbb6f0c90ff9e 695 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 18 37 2.0E-8 T 12-10-2018 TSC_c04500 7f6a1f75dfb025b746fbbb6f0c90ff9e 695 SUPERFAMILY SSF52540 17 416 2.47E-6 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c04500 7f6a1f75dfb025b746fbbb6f0c90ff9e 695 SUPERFAMILY SSF54211 478 670 1.1E-31 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c04500 7f6a1f75dfb025b746fbbb6f0c90ff9e 695 Pfam PF13654 AAA domain 163 453 2.7E-38 T 12-10-2018 TSC_c04500 7f6a1f75dfb025b746fbbb6f0c90ff9e 695 Pfam PF13654 AAA domain 16 154 2.8E-12 T 12-10-2018 TSC_c04500 7f6a1f75dfb025b746fbbb6f0c90ff9e 695 Gene3D G3DSA:3.30.230.10 455 690 4.1E-86 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSC_c04500 7f6a1f75dfb025b746fbbb6f0c90ff9e 695 Gene3D G3DSA:1.10.8.60 377 453 1.9E-29 T 12-10-2018 TSC_c15610 658a1b284274f9cadac7f5d0fe8773c7 344 Pfam PF00557 Metallopeptidase family M24 126 327 5.6E-60 T 12-10-2018 IPR000994 Peptidase M24 TSC_c15610 658a1b284274f9cadac7f5d0fe8773c7 344 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 274 286 - T 12-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site TSC_c15610 658a1b284274f9cadac7f5d0fe8773c7 344 SUPERFAMILY SSF53092 6 118 2.62E-21 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TSC_c15610 658a1b284274f9cadac7f5d0fe8773c7 344 Gene3D G3DSA:3.90.230.10 120 340 4.9E-77 T 12-10-2018 TSC_c15610 658a1b284274f9cadac7f5d0fe8773c7 344 SUPERFAMILY SSF55920 120 343 6.67E-74 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like TSC_c15610 658a1b284274f9cadac7f5d0fe8773c7 344 Pfam PF01321 Creatinase/Prolidase N-terminal domain 8 118 1.6E-21 T 12-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 TSC_c15610 658a1b284274f9cadac7f5d0fe8773c7 344 Gene3D G3DSA:3.40.350.10 5 117 2.1E-23 T 12-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal TSC_c15610 658a1b284274f9cadac7f5d0fe8773c7 344 PRINTS PR00599 Methionine aminopeptidase-1 signature 198 214 8.3E-6 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSC_c15610 658a1b284274f9cadac7f5d0fe8773c7 344 PRINTS PR00599 Methionine aminopeptidase-1 signature 296 308 8.3E-6 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSC_c24420 c6937dfe6a026dd26749d6bf147277b4 82 SUPERFAMILY SSF89447 1 53 2.88E-8 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily TSC_c24420 c6937dfe6a026dd26749d6bf147277b4 82 Gene3D G3DSA:2.10.260.10 1 42 2.0E-7 T 12-10-2018 TSC_c24420 c6937dfe6a026dd26749d6bf147277b4 82 SMART SM00966 4 50 2.5E-8 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TSC_c24420 c6937dfe6a026dd26749d6bf147277b4 82 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 45 9.3E-8 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TSC_c05010 101bbf55ed29965facc7c787740aebb3 350 Pfam PF14343 PrcB C-terminal 275 330 8.7E-14 T 12-10-2018 IPR025748 PrcB C-terminal domain TSC_c22450 f25e9871b1351f6d867c0aee9065e7df 105 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 3 99 2.8E-43 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22450 f25e9871b1351f6d867c0aee9065e7df 105 ProSitePatterns PS00361 Ribosomal protein S10 signature. 27 42 - T 12-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22450 f25e9871b1351f6d867c0aee9065e7df 105 SUPERFAMILY SSF54999 3 99 2.22E-35 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TSC_c22450 f25e9871b1351f6d867c0aee9065e7df 105 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 1 100 25.918 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22450 f25e9871b1351f6d867c0aee9065e7df 105 Pfam PF00338 Ribosomal protein S10p/S20e 5 99 1.1E-33 T 12-10-2018 IPR027486 Ribosomal protein S10 domain TSC_c22450 f25e9871b1351f6d867c0aee9065e7df 105 Gene3D G3DSA:3.30.70.600 1 105 9.8E-39 T 12-10-2018 IPR036838 Ribosomal protein S10 domain superfamily TSC_c22450 f25e9871b1351f6d867c0aee9065e7df 105 SMART SM01403 5 99 1.9E-52 T 12-10-2018 IPR027486 Ribosomal protein S10 domain TSC_c22450 f25e9871b1351f6d867c0aee9065e7df 105 PRINTS PR00971 Ribosomal protein S10 family signature 59 73 8.0E-19 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22450 f25e9871b1351f6d867c0aee9065e7df 105 PRINTS PR00971 Ribosomal protein S10 family signature 38 53 8.0E-19 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22450 f25e9871b1351f6d867c0aee9065e7df 105 PRINTS PR00971 Ribosomal protein S10 family signature 3 16 8.0E-19 T 12-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c07650 71927975bd64b19613cc8200d92009bd 470 ProSitePatterns PS00450 Aconitase family signature 1. 338 354 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TSC_c07650 71927975bd64b19613cc8200d92009bd 470 Gene3D G3DSA:3.30.499.20 4 286 5.9E-93 T 12-10-2018 TSC_c07650 71927975bd64b19613cc8200d92009bd 470 PRINTS PR00415 Aconitase family signature 119 132 1.4E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c07650 71927975bd64b19613cc8200d92009bd 470 PRINTS PR00415 Aconitase family signature 108 116 1.4E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c07650 71927975bd64b19613cc8200d92009bd 470 PRINTS PR00415 Aconitase family signature 209 222 1.4E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c07650 71927975bd64b19613cc8200d92009bd 470 PRINTS PR00415 Aconitase family signature 398 411 1.4E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c07650 71927975bd64b19613cc8200d92009bd 470 PRINTS PR00415 Aconitase family signature 195 208 1.4E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c07650 71927975bd64b19613cc8200d92009bd 470 PRINTS PR00415 Aconitase family signature 286 300 1.4E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c07650 71927975bd64b19613cc8200d92009bd 470 PRINTS PR00415 Aconitase family signature 133 148 1.4E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c07650 71927975bd64b19613cc8200d92009bd 470 PRINTS PR00415 Aconitase family signature 342 353 1.4E-39 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c07650 71927975bd64b19613cc8200d92009bd 470 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 465 1.4E-187 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TSC_c07650 71927975bd64b19613cc8200d92009bd 470 SUPERFAMILY SSF53732 1 465 1.57E-155 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 TSC_c07650 71927975bd64b19613cc8200d92009bd 470 Pfam PF00330 Aconitase family (aconitate hydratase) 7 457 1.2E-145 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c07650 71927975bd64b19613cc8200d92009bd 470 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 466 56.757 T 12-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TSC_c07650 71927975bd64b19613cc8200d92009bd 470 Gene3D G3DSA:3.30.499.10 325 465 1.5E-48 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 TSC_c07650 71927975bd64b19613cc8200d92009bd 470 ProSitePatterns PS01244 Aconitase family signature 2. 398 411 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TSC_c17470 8d494d5cf41e9da037a62689dc8a739c 443 Gene3D G3DSA:1.20.1250.20 213 430 1.9E-58 T 12-10-2018 TSC_c17470 8d494d5cf41e9da037a62689dc8a739c 443 Pfam PF07690 Major Facilitator Superfamily 24 310 1.5E-30 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c17470 8d494d5cf41e9da037a62689dc8a739c 443 Gene3D G3DSA:1.20.1250.20 4 203 2.5E-48 T 12-10-2018 TSC_c17470 8d494d5cf41e9da037a62689dc8a739c 443 SUPERFAMILY SSF103473 8 425 6.8E-63 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c20580 5bc3343d18e145e46f47a5d6e43d35dc 137 Pfam PF02566 OsmC-like protein 28 124 5.0E-19 T 12-10-2018 IPR003718 OsmC/Ohr family TSC_c20580 5bc3343d18e145e46f47a5d6e43d35dc 137 Gene3D G3DSA:3.30.300.20 2 128 7.0E-33 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TSC_c20580 5bc3343d18e145e46f47a5d6e43d35dc 137 SUPERFAMILY SSF82784 5 127 5.89E-35 T 12-10-2018 IPR036102 OsmC/Ohr superfamily TSC_c24430 7bfcb35bfe703be5cc5d8eaa5b268ff3 147 SUPERFAMILY SSF88723 1 119 1.37E-14 T 12-10-2018 IPR029060 PIN-like domain superfamily TSC_c24430 7bfcb35bfe703be5cc5d8eaa5b268ff3 147 Gene3D G3DSA:3.40.50.1010 1 122 1.5E-5 T 12-10-2018 TSC_c24430 7bfcb35bfe703be5cc5d8eaa5b268ff3 147 Pfam PF13470 PIN domain 2 110 2.2E-11 T 12-10-2018 IPR002716 PIN domain TSC_c08940 3590d83a5460fbf14349e12749164155 327 SUPERFAMILY SSF55874 173 322 4.64E-24 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c08940 3590d83a5460fbf14349e12749164155 327 Gene3D G3DSA:3.30.565.10 185 326 5.1E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c08940 3590d83a5460fbf14349e12749164155 327 SMART SM00388 116 183 2.2E-4 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c08940 3590d83a5460fbf14349e12749164155 327 PRINTS PR00344 Bacterial sensor protein C-terminal signature 255 269 9.7E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c08940 3590d83a5460fbf14349e12749164155 327 PRINTS PR00344 Bacterial sensor protein C-terminal signature 309 322 9.7E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c08940 3590d83a5460fbf14349e12749164155 327 PRINTS PR00344 Bacterial sensor protein C-terminal signature 285 303 9.7E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c08940 3590d83a5460fbf14349e12749164155 327 SUPERFAMILY SSF47384 101 182 3.53E-12 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSC_c08940 3590d83a5460fbf14349e12749164155 327 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 228 323 1.6E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c08940 3590d83a5460fbf14349e12749164155 327 Gene3D G3DSA:1.10.287.130 61 184 9.7E-12 T 12-10-2018 TSC_c08940 3590d83a5460fbf14349e12749164155 327 SMART SM00387 224 325 9.9E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c18960 294835e6c2caf47c7ce93d92fe9744b2 232 SUPERFAMILY SSF46548 103 228 1.13E-32 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSC_c18960 294835e6c2caf47c7ce93d92fe9744b2 232 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 7 224 5.1E-79 T 12-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c18960 294835e6c2caf47c7ce93d92fe9744b2 232 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 144 155 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c18960 294835e6c2caf47c7ce93d92fe9744b2 232 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 107 5.0E-35 T 12-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c18960 294835e6c2caf47c7ce93d92fe9744b2 232 Gene3D G3DSA:3.10.20.30 1 102 1.7E-34 T 12-10-2018 IPR012675 Beta-grasp domain superfamily TSC_c18960 294835e6c2caf47c7ce93d92fe9744b2 232 Gene3D G3DSA:1.10.1060.10 103 230 3.9E-46 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSC_c18960 294835e6c2caf47c7ce93d92fe9744b2 232 Pfam PF13237 4Fe-4S dicluster domain 142 211 3.2E-10 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c18960 294835e6c2caf47c7ce93d92fe9744b2 232 SUPERFAMILY SSF54292 1 102 3.28E-32 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSC_c11240 2e66ab1003a0941641da134c03a29fd8 756 SUPERFAMILY SSF74650 2 245 2.04E-59 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 TSC_c11240 2e66ab1003a0941641da134c03a29fd8 756 Pfam PF09137 Glucodextranase, domain N 3 245 2.6E-69 T 12-10-2018 IPR015220 Glucodextranase, N-terminal KEGG: 00500+3.2.1.3|MetaCyc: PWY-5941 TSC_c11240 2e66ab1003a0941641da134c03a29fd8 756 ProSitePatterns PS00820 Glucoamylase active site region signature. 400 410 - T 12-10-2018 IPR000165 Glucoamylase GO:0004339|GO:0005976 KEGG: 00500+3.2.1.3|MetaCyc: PWY-5941 TSC_c11240 2e66ab1003a0941641da134c03a29fd8 756 Pfam PF00723 Glycosyl hydrolases family 15 347 641 1.3E-8 T 12-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 TSC_c11240 2e66ab1003a0941641da134c03a29fd8 756 Pfam PF00723 Glycosyl hydrolases family 15 266 325 4.7E-5 T 12-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 TSC_c11240 2e66ab1003a0941641da134c03a29fd8 756 Gene3D G3DSA:1.50.10.10 253 667 4.0E-136 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TSC_c11240 2e66ab1003a0941641da134c03a29fd8 756 SUPERFAMILY SSF48208 255 650 3.06E-69 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TSC_c11240 2e66ab1003a0941641da134c03a29fd8 756 Gene3D G3DSA:2.70.98.10 1 247 1.1E-62 T 12-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 TSC_c06240 19e23b0c03486d1b2ab83682c596091c 318 Pfam PF05982 Na+-dependent bicarbonate transporter superfamily 14 314 1.7E-106 T 12-10-2018 IPR010293 Na+-dependent bicarbonate transporter superfamily TSC_c21030 857d059e121fb21f81b0cfb37d952e1b 283 SUPERFAMILY SSF103247 20 135 7.98E-12 T 12-10-2018 IPR035923 TT1751-like domain superfamily TSC_c21030 857d059e121fb21f81b0cfb37d952e1b 283 SUPERFAMILY SSF103247 167 273 6.28E-11 T 12-10-2018 IPR035923 TT1751-like domain superfamily TSC_c23230 450524780810c45eed2ccb7e01755300 626 SUPERFAMILY SSF53850 21 604 8.14E-82 T 12-10-2018 TSC_c23230 450524780810c45eed2ccb7e01755300 626 PIRSF PIRSF002741 18 188 1.6E-7 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSC_c23230 450524780810c45eed2ccb7e01755300 626 PIRSF PIRSF002741 218 605 2.3E-44 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSC_c23230 450524780810c45eed2ccb7e01755300 626 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 102 494 1.2E-52 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TSC_c23230 450524780810c45eed2ccb7e01755300 626 Gene3D G3DSA:3.90.76.10 65 185 0.0 T 12-10-2018 TSC_c23230 450524780810c45eed2ccb7e01755300 626 Gene3D G3DSA:3.10.105.10 331 578 0.0 T 12-10-2018 TSC_c23230 450524780810c45eed2ccb7e01755300 626 Gene3D G3DSA:3.40.190.10 21 614 0.0 T 12-10-2018 TSC_c20730 b0ad38f8f6533d72e386ed1a0eaa3819 344 SUPERFAMILY SSF56796 1 338 9.94E-83 T 12-10-2018 TSC_c20730 b0ad38f8f6533d72e386ed1a0eaa3819 344 PIRSF PIRSF001455 4 343 2.2E-94 T 12-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TSC_c20730 b0ad38f8f6533d72e386ed1a0eaa3819 344 Gene3D G3DSA:1.20.1090.10 162 338 7.8E-53 T 12-10-2018 TSC_c20730 b0ad38f8f6533d72e386ed1a0eaa3819 344 Gene3D G3DSA:3.40.50.1970 1 161 1.0E-52 T 12-10-2018 TSC_c20730 b0ad38f8f6533d72e386ed1a0eaa3819 344 Pfam PF01761 3-dehydroquinate synthase 58 304 1.6E-73 T 12-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 TSC_c24360 74064a780a802803e7075356cdc5ec6a 380 Gene3D G3DSA:3.40.720.10 2 379 1.0E-142 T 12-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 TSC_c24360 74064a780a802803e7075356cdc5ec6a 380 TIGRFAM TIGR01696 deoB: phosphopentomutase 3 377 1.1E-124 T 12-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 TSC_c24360 74064a780a802803e7075356cdc5ec6a 380 SUPERFAMILY SSF53649 1 380 7.85E-66 T 12-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 TSC_c24360 74064a780a802803e7075356cdc5ec6a 380 PIRSF PIRSF001491 1 380 2.3E-138 T 12-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 TSC_c24360 74064a780a802803e7075356cdc5ec6a 380 Pfam PF01676 Metalloenzyme superfamily 2 370 8.2E-24 T 12-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 TSC_c24360 74064a780a802803e7075356cdc5ec6a 380 Hamap MF_00740 Phosphopentomutase [deoB]. 1 380 44.91 T 12-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 TSC_c24360 74064a780a802803e7075356cdc5ec6a 380 Gene3D G3DSA:3.30.70.1250 93 212 1.0E-142 T 12-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 TSC_c24360 74064a780a802803e7075356cdc5ec6a 380 SUPERFAMILY SSF143856 95 212 1.57E-43 T 12-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 TSC_c19060 3c1b757b91aefb1d259e57c476ef1319 208 Pfam PF00156 Phosphoribosyl transferase domain 9 186 5.7E-27 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSC_c19060 3c1b757b91aefb1d259e57c476ef1319 208 SUPERFAMILY SSF53271 1 203 7.47E-51 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TSC_c19060 3c1b757b91aefb1d259e57c476ef1319 208 Gene3D G3DSA:3.30.1310.20 53 110 3.2E-26 T 12-10-2018 TSC_c18510 7c2824df5bd4270421a688ce8b576c67 370 SUPERFAMILY SSF51905 2 362 2.33E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c18510 7c2824df5bd4270421a688ce8b576c67 370 Gene3D G3DSA:3.30.9.10 78 301 5.7E-88 T 12-10-2018 TSC_c18510 7c2824df5bd4270421a688ce8b576c67 370 Gene3D G3DSA:3.50.50.60 4 338 5.7E-88 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c18510 7c2824df5bd4270421a688ce8b576c67 370 Pfam PF01266 FAD dependent oxidoreductase 4 338 1.8E-56 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSC_c08790 4c57c46d555691c8d4444390913bcf05 478 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 350 359 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSC_c08790 4c57c46d555691c8d4444390913bcf05 478 SUPERFAMILY SSF47917 372 426 5.23E-6 T 12-10-2018 TSC_c08790 4c57c46d555691c8d4444390913bcf05 478 PIRSF PIRSF039114 1 472 1.6E-240 T 12-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c08790 4c57c46d555691c8d4444390913bcf05 478 SUPERFAMILY SSF52540 82 364 3.13E-82 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c08790 4c57c46d555691c8d4444390913bcf05 478 Gene3D G3DSA:3.40.50.12240 1 464 4.4E-188 T 12-10-2018 TSC_c08790 4c57c46d555691c8d4444390913bcf05 478 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 11 68 3.0E-8 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSC_c08790 4c57c46d555691c8d4444390913bcf05 478 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 5 467 58.986 T 12-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c08790 4c57c46d555691c8d4444390913bcf05 478 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 134 359 1.6E-65 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSC_c17150 696eecac725beca55ce382a3df2bc6ca 263 Gene3D G3DSA:3.40.30.10 123 255 6.4E-34 T 12-10-2018 TSC_c17150 696eecac725beca55ce382a3df2bc6ca 263 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 3 119 3.2E-7 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TSC_c17150 696eecac725beca55ce382a3df2bc6ca 263 Pfam PF08534 Redoxin 132 250 2.6E-17 T 12-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 TSC_c17150 696eecac725beca55ce382a3df2bc6ca 263 SUPERFAMILY SSF52833 134 259 1.83E-33 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TSC_c17150 696eecac725beca55ce382a3df2bc6ca 263 ProSitePatterns PS00194 Thioredoxin family active site. 157 175 - T 12-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 TSC_c19010 d468b29af1ecc9e85af8f721fa3a0003 144 Gene3D G3DSA:3.60.90.10 5 133 1.1E-35 T 12-10-2018 TSC_c19010 d468b29af1ecc9e85af8f721fa3a0003 144 Pfam PF02675 S-adenosylmethionine decarboxylase 9 118 6.9E-28 T 12-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TSC_c19010 d468b29af1ecc9e85af8f721fa3a0003 144 SUPERFAMILY SSF56276 6 119 5.1E-26 T 12-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 TSC_c19010 d468b29af1ecc9e85af8f721fa3a0003 144 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 6 118 5.1E-23 T 12-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TSC_c22300 7ea605873e8602f6a1635fc6ed985550 138 Gene3D G3DSA:3.30.1370.30 3 80 3.9E-35 T 12-10-2018 TSC_c22300 7ea605873e8602f6a1635fc6ed985550 138 SUPERFAMILY SSF56047 1 138 5.49E-48 T 12-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22300 7ea605873e8602f6a1635fc6ed985550 138 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 1 138 32.466 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22300 7ea605873e8602f6a1635fc6ed985550 138 ProSitePatterns PS00053 Ribosomal protein S8 signature. 108 125 - T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22300 7ea605873e8602f6a1635fc6ed985550 138 Pfam PF00410 Ribosomal protein S8 4 138 6.6E-49 T 12-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22300 7ea605873e8602f6a1635fc6ed985550 138 Gene3D G3DSA:3.30.1490.10 81 138 5.0E-28 T 12-10-2018 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 SUPERFAMILY SSF50677 221 369 7.33E-54 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 SUPERFAMILY SSF46589 826 890 1.94E-11 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 TIGRFAM TIGR00422 valS: valine--tRNA ligase 33 873 6.9E-302 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 Hamap MF_02004 Valine--tRNA ligase [valS]. 32 891 14.561 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 Gene3D G3DSA:3.40.50.620 52 558 0.0 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 72 83 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 PRINTS PR00986 Valyl-tRNA synthetase signature 375 388 5.0E-35 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 PRINTS PR00986 Valyl-tRNA synthetase signature 509 527 5.0E-35 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 PRINTS PR00986 Valyl-tRNA synthetase signature 65 76 5.0E-35 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 PRINTS PR00986 Valyl-tRNA synthetase signature 478 499 5.0E-35 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 PRINTS PR00986 Valyl-tRNA synthetase signature 258 275 5.0E-35 T 12-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 Gene3D G3DSA:1.10.287.380 819 891 1.1E-27 T 12-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 SUPERFAMILY SSF47323 608 824 2.8E-49 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 Gene3D G3DSA:3.90.740.10 204 372 0.0 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 SUPERFAMILY SSF52374 31 607 4.29E-141 T 12-10-2018 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 Gene3D G3DSA:3.30.1170.10 769 818 8.0E-26 T 12-10-2018 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 45 597 2.4E-188 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 Pfam PF08264 Anticodon-binding domain of tRNA 636 777 9.8E-36 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 Gene3D G3DSA:1.10.730.10 32 763 0.0 T 12-10-2018 TSC_c14920 4d466ba0e9cef90133932c26084bbf2a 891 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 826 890 1.8E-20 T 12-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 TSC_c14840 2809b469c8eacf5cd0286f3d62c3830f 302 SUPERFAMILY SSF51735 99 261 1.28E-40 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c14840 2809b469c8eacf5cd0286f3d62c3830f 302 Gene3D G3DSA:3.90.180.10 16 299 5.3E-101 T 12-10-2018 TSC_c14840 2809b469c8eacf5cd0286f3d62c3830f 302 SUPERFAMILY SSF50129 1 132 3.5E-34 T 12-10-2018 IPR011032 GroES-like superfamily TSC_c14840 2809b469c8eacf5cd0286f3d62c3830f 302 Pfam PF00107 Zinc-binding dehydrogenase 137 251 1.3E-21 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSC_c14840 2809b469c8eacf5cd0286f3d62c3830f 302 SMART SM00829 11 300 2.1E-29 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSC_c14840 2809b469c8eacf5cd0286f3d62c3830f 302 Gene3D G3DSA:3.40.50.720 110 270 5.3E-101 T 12-10-2018 TSC_c23620 b0e5b69e351abcbfaee37ef5627b9e83 405 SUPERFAMILY SSF53850 25 402 6.73E-75 T 12-10-2018 TSC_c23620 b0e5b69e351abcbfaee37ef5627b9e83 405 Pfam PF13416 Bacterial extracellular solute-binding protein 45 337 2.2E-35 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSC_c23620 b0e5b69e351abcbfaee37ef5627b9e83 405 Gene3D G3DSA:3.40.190.10 141 400 4.9E-88 T 12-10-2018 TSC_c23620 b0e5b69e351abcbfaee37ef5627b9e83 405 Gene3D G3DSA:3.40.190.10 29 364 4.9E-88 T 12-10-2018 TSC_c08860 6675d09063a264edec7a47707db4678d 422 SUPERFAMILY SSF56954 4 419 7.72E-35 T 12-10-2018 TSC_c08860 6675d09063a264edec7a47707db4678d 422 Pfam PF02321 Outer membrane efflux protein 23 192 3.1E-10 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSC_c08860 6675d09063a264edec7a47707db4678d 422 Pfam PF02321 Outer membrane efflux protein 216 414 1.5E-17 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSC_c08860 6675d09063a264edec7a47707db4678d 422 Gene3D G3DSA:1.20.1600.10 19 419 6.4E-36 T 12-10-2018 TSC_c02570 2802e776c9472b82490a776b4c49bc6a 400 SUPERFAMILY SSF55874 266 398 6.68E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c02570 2802e776c9472b82490a776b4c49bc6a 400 SMART SM00388 198 261 7.1E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c02570 2802e776c9472b82490a776b4c49bc6a 400 Gene3D G3DSA:3.30.565.10 261 398 4.0E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c02570 2802e776c9472b82490a776b4c49bc6a 400 Pfam PF00512 His Kinase A (phospho-acceptor) domain 200 259 1.3E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c02570 2802e776c9472b82490a776b4c49bc6a 400 Pfam PF00672 HAMP domain 146 194 1.1E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSC_c02570 2802e776c9472b82490a776b4c49bc6a 400 SUPERFAMILY SSF47384 181 257 6.08E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSC_c02570 2802e776c9472b82490a776b4c49bc6a 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 377 3.8E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c02570 2802e776c9472b82490a776b4c49bc6a 400 PRINTS PR00344 Bacterial sensor protein C-terminal signature 329 343 3.8E-8 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c02570 2802e776c9472b82490a776b4c49bc6a 400 Gene3D G3DSA:1.10.287.130 148 260 3.5E-24 T 12-10-2018 TSC_c02570 2802e776c9472b82490a776b4c49bc6a 400 SMART SM00387 293 399 1.4E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c02570 2802e776c9472b82490a776b4c49bc6a 400 SUPERFAMILY SSF158472 147 194 1.02E-7 T 12-10-2018 TSC_c02570 2802e776c9472b82490a776b4c49bc6a 400 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 293 398 3.4E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c02570 2802e776c9472b82490a776b4c49bc6a 400 SMART SM00304 144 197 1.1E-13 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSC_c21500 7de5a90e0af38bc5b171402c22e43519 255 SUPERFAMILY SSF56300 18 253 8.16E-47 T 12-10-2018 TSC_c21500 7de5a90e0af38bc5b171402c22e43519 255 Pfam PF00149 Calcineurin-like phosphoesterase 18 184 4.9E-17 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSC_c21500 7de5a90e0af38bc5b171402c22e43519 255 Gene3D G3DSA:3.60.21.10 16 254 6.5E-33 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TSC_c07300 0c8fdc31f8eee08510b44a7021260953 264 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 49 256 2.8E-62 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 TSC_c07300 0c8fdc31f8eee08510b44a7021260953 264 Gene3D G3DSA:3.90.850.10 45 264 7.4E-87 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSC_c07300 0c8fdc31f8eee08510b44a7021260953 264 Pfam PF10370 Domain of unknown function (DUF2437) 1 44 1.9E-8 T 12-10-2018 IPR018833 Domain of unknown function DUF2437 TSC_c07300 0c8fdc31f8eee08510b44a7021260953 264 Gene3D G3DSA:2.30.30.370 1 44 3.3E-29 T 12-10-2018 TSC_c07300 0c8fdc31f8eee08510b44a7021260953 264 SUPERFAMILY SSF56529 47 257 3.92E-74 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSC_c01920 a18d1e49a0e3660ae1aa783e212da0ca 298 Gene3D G3DSA:3.30.470.80 188 295 2.7E-42 T 12-10-2018 TSC_c01920 a18d1e49a0e3660ae1aa783e212da0ca 298 SUPERFAMILY SSF52440 16 103 1.41E-22 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSC_c01920 a18d1e49a0e3660ae1aa783e212da0ca 298 SUPERFAMILY SSF56059 104 290 3.7E-47 T 12-10-2018 TSC_c01920 a18d1e49a0e3660ae1aa783e212da0ca 298 Gene3D G3DSA:3.40.50.20 12 117 2.1E-32 T 12-10-2018 TSC_c01920 a18d1e49a0e3660ae1aa783e212da0ca 298 Gene3D G3DSA:3.30.1490.20 119 187 3.1E-30 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSC_c01920 a18d1e49a0e3660ae1aa783e212da0ca 298 Pfam PF08443 RimK-like ATP-grasp domain 103 289 4.1E-30 T 12-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 TSC_c01920 a18d1e49a0e3660ae1aa783e212da0ca 298 TIGRFAM TIGR00768 rimK_fam: alpha-L-glutamate ligase, RimK family 17 289 1.9E-107 T 12-10-2018 IPR004666 Ribosomal S6 modification enzyme RimK/Lysine biosynthesis enzyme LysX GO:0006464 Reactome: R-HSA-70614 TSC_c01920 a18d1e49a0e3660ae1aa783e212da0ca 298 TIGRFAM TIGR02144 LysX_arch: lysine biosynthesis enzyme LysX 17 292 2.1E-125 T 12-10-2018 IPR011870 Lysine biosynthesis enzyme LysX GO:0003824|GO:0005524|GO:0009085 TSC_c23310 ee4df2061e2799326fa56a3c0a9dfc9f 392 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 268 276 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSC_c23310 ee4df2061e2799326fa56a3c0a9dfc9f 392 Gene3D G3DSA:3.30.300.10 9 280 1.7E-172 T 12-10-2018 TSC_c23310 ee4df2061e2799326fa56a3c0a9dfc9f 392 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 242 378 2.2E-63 T 12-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSC_c23310 ee4df2061e2799326fa56a3c0a9dfc9f 392 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 3 99 7.0E-40 T 12-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSC_c23310 ee4df2061e2799326fa56a3c0a9dfc9f 392 Gene3D G3DSA:3.30.300.10 108 384 1.7E-172 T 12-10-2018 TSC_c23310 ee4df2061e2799326fa56a3c0a9dfc9f 392 SUPERFAMILY SSF55973 3 107 2.2E-43 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSC_c23310 ee4df2061e2799326fa56a3c0a9dfc9f 392 PIRSF PIRSF000497 1 391 1.1E-163 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSC_c23310 ee4df2061e2799326fa56a3c0a9dfc9f 392 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 124 134 - T 12-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSC_c23310 ee4df2061e2799326fa56a3c0a9dfc9f 392 SUPERFAMILY SSF55973 242 390 2.08E-65 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSC_c23310 ee4df2061e2799326fa56a3c0a9dfc9f 392 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 4 388 1.3E-171 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSC_c23310 ee4df2061e2799326fa56a3c0a9dfc9f 392 Gene3D G3DSA:3.30.300.10 4 243 1.7E-172 T 12-10-2018 TSC_c23310 ee4df2061e2799326fa56a3c0a9dfc9f 392 SUPERFAMILY SSF55973 119 241 1.41E-48 T 12-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSC_c23310 ee4df2061e2799326fa56a3c0a9dfc9f 392 Pfam PF02772 S-adenosylmethionine synthetase, central domain 123 240 4.1E-45 T 12-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSC_c23310 ee4df2061e2799326fa56a3c0a9dfc9f 392 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 1 390 55.16 T 12-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 TSC_c05840 6df6a2d66e324db01a60a86e26d5786a 80 SUPERFAMILY SSF47336 1 79 2.75E-25 T 12-10-2018 IPR036736 ACP-like superfamily TSC_c05840 6df6a2d66e324db01a60a86e26d5786a 80 Pfam PF00550 Phosphopantetheine attachment site 8 75 3.2E-15 T 12-10-2018 IPR009081 Phosphopantetheine binding ACP domain TSC_c05840 6df6a2d66e324db01a60a86e26d5786a 80 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 43 79 5.0E-12 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 TSC_c05840 6df6a2d66e324db01a60a86e26d5786a 80 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 4 77 8.8E-35 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 TSC_c05840 6df6a2d66e324db01a60a86e26d5786a 80 ProSitePatterns PS00012 Phosphopantetheine attachment site. 34 49 - T 12-10-2018 IPR006162 Phosphopantetheine attachment site TSC_c05840 6df6a2d66e324db01a60a86e26d5786a 80 Gene3D G3DSA:1.10.1200.10 1 79 6.1E-31 T 12-10-2018 IPR036736 ACP-like superfamily TSC_c05840 6df6a2d66e324db01a60a86e26d5786a 80 Hamap MF_01217 Acyl carrier protein [acpP]. 5 79 22.977 T 12-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 TSC_c07680 68a47822acdebc2fa8aaa2bf823b686b 337 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 327 2.7E-93 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TSC_c07680 68a47822acdebc2fa8aaa2bf823b686b 337 Gene3D G3DSA:1.10.240.10 189 295 3.2E-135 T 12-10-2018 TSC_c07680 68a47822acdebc2fa8aaa2bf823b686b 337 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c07680 68a47822acdebc2fa8aaa2bf823b686b 337 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 328 39.026 T 12-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 TSC_c07680 68a47822acdebc2fa8aaa2bf823b686b 337 SUPERFAMILY SSF52374 2 327 8.36E-90 T 12-10-2018 TSC_c07680 68a47822acdebc2fa8aaa2bf823b686b 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 1.5E-25 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TSC_c07680 68a47822acdebc2fa8aaa2bf823b686b 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 195 205 1.5E-25 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TSC_c07680 68a47822acdebc2fa8aaa2bf823b686b 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 143 164 1.5E-25 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TSC_c07680 68a47822acdebc2fa8aaa2bf823b686b 337 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 68 87 1.5E-25 T 12-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 TSC_c07680 68a47822acdebc2fa8aaa2bf823b686b 337 Pfam PF00579 tRNA synthetases class I (W and Y) 2 281 1.5E-70 T 12-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c07680 68a47822acdebc2fa8aaa2bf823b686b 337 Gene3D G3DSA:3.40.50.620 3 327 3.2E-135 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 Gene3D G3DSA:3.20.20.330 38 349 2.4E-94 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 Pfam PF02310 B12 binding domain 750 864 1.6E-20 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 SUPERFAMILY SSF47644 659 743 4.97E-26 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 Pfam PF02574 Homocysteine S-methyltransferase 50 337 2.7E-64 T 12-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 TIGRFAM TIGR02082 metH: methionine synthase 47 1181 0.0 T 12-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 Gene3D G3DSA:1.10.1240.10 654 742 1.2E-31 T 12-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 SUPERFAMILY SSF82282 40 411 1.83E-109 T 12-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 PIRSF PIRSF000381 34 1182 0.0 T 12-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 SMART SM01018 662 745 3.2E-40 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 Pfam PF00809 Pterin binding enzyme 372 605 1.5E-46 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 SUPERFAMILY SSF52242 745 873 3.53E-37 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 Gene3D G3DSA:3.40.50.280 747 884 2.1E-43 T 12-10-2018 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 Gene3D G3DSA:3.20.20.20 357 650 1.9E-93 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 963 1181 3.1E-37 T 12-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 Gene3D G3DSA:3.10.196.10 904 1181 2.7E-48 T 12-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 SUPERFAMILY SSF51717 369 637 5.63E-73 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 SUPERFAMILY SSF56507 893 1181 4.97E-83 T 12-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 Gene3D G3DSA:1.10.288.10 919 977 2.7E-48 T 12-10-2018 TSC_c14020 e1a9ec584562c4c0dadaa760a8c9d75e 1182 Pfam PF02607 B12 binding domain 664 738 1.9E-27 T 12-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c23660 85eb1dab6bfcfc2c15c1021f910c87db 209 Pfam PF00355 Rieske [2Fe-2S] domain 103 179 5.2E-12 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TSC_c23660 85eb1dab6bfcfc2c15c1021f910c87db 209 Gene3D G3DSA:2.102.10.10 46 208 2.0E-55 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSC_c23660 85eb1dab6bfcfc2c15c1021f910c87db 209 PRINTS PR00162 Rieske 2Fe-2S subunit signature 149 161 4.8E-8 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TSC_c23660 85eb1dab6bfcfc2c15c1021f910c87db 209 PRINTS PR00162 Rieske 2Fe-2S subunit signature 163 175 4.8E-8 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TSC_c23660 85eb1dab6bfcfc2c15c1021f910c87db 209 PRINTS PR00162 Rieske 2Fe-2S subunit signature 127 138 4.8E-8 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TSC_c23660 85eb1dab6bfcfc2c15c1021f910c87db 209 SUPERFAMILY SSF50022 58 192 5.11E-31 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSC_c04390 04372a5d6c587d8f9cd7cb0fa46fb30b 160 Gene3D G3DSA:3.40.630.30 2 158 5.3E-43 T 12-10-2018 TSC_c04390 04372a5d6c587d8f9cd7cb0fa46fb30b 160 Pfam PF13302 Acetyltransferase (GNAT) domain 7 123 2.1E-21 T 12-10-2018 IPR000182 GNAT domain TSC_c04390 04372a5d6c587d8f9cd7cb0fa46fb30b 160 SUPERFAMILY SSF55729 10 147 3.09E-36 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSC_c06840 c5804386243aa54355b307db5f5634d1 323 Gene3D G3DSA:3.40.190.150 29 314 4.6E-74 T 12-10-2018 TSC_c06840 c5804386243aa54355b307db5f5634d1 323 Gene3D G3DSA:3.40.190.10 124 249 4.6E-74 T 12-10-2018 TSC_c06840 c5804386243aa54355b307db5f5634d1 323 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 49 321 1.3E-45 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSC_c06840 c5804386243aa54355b307db5f5634d1 323 SUPERFAMILY SSF53850 113 286 1.18E-9 T 12-10-2018 TSC_c06840 c5804386243aa54355b307db5f5634d1 323 PIRSF PIRSF017082 2 322 1.2E-76 T 12-10-2018 IPR005064 Bordetella uptake gene GO:0030288 TSC_c21700 70da156ef1d3b35571326952802a28b8 392 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 86 109 - T 12-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TSC_c21700 70da156ef1d3b35571326952802a28b8 392 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 6 338 9.9E-100 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TSC_c21700 70da156ef1d3b35571326952802a28b8 392 Gene3D G3DSA:3.30.460.30 4 147 7.8E-45 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TSC_c21700 70da156ef1d3b35571326952802a28b8 392 Gene3D G3DSA:3.40.50.720 148 295 1.3E-42 T 12-10-2018 TSC_c21700 70da156ef1d3b35571326952802a28b8 392 PIRSF PIRSF000445 3 361 1.1E-119 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TSC_c21700 70da156ef1d3b35571326952802a28b8 392 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 4 376 26.457 T 12-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TSC_c21700 70da156ef1d3b35571326952802a28b8 392 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 8 143 7.8E-41 T 12-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TSC_c21700 70da156ef1d3b35571326952802a28b8 392 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 159 288 9.3E-36 T 12-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase TSC_c21700 70da156ef1d3b35571326952802a28b8 392 SUPERFAMILY SSF51735 148 297 9.44E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c21700 70da156ef1d3b35571326952802a28b8 392 SUPERFAMILY SSF69742 4 145 6.28E-42 T 12-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 TSC_c09030 34c28082eb4766357766c5caf8066b03 241 Gene3D G3DSA:3.40.50.300 2 239 1.1E-62 T 12-10-2018 TSC_c09030 34c28082eb4766357766c5caf8066b03 241 Pfam PF00005 ABC transporter 20 167 2.2E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c09030 34c28082eb4766357766c5caf8066b03 241 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 216 238 7.7E-9 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSC_c09030 34c28082eb4766357766c5caf8066b03 241 SUPERFAMILY SSF52540 4 237 6.63E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c09030 34c28082eb4766357766c5caf8066b03 241 SMART SM00382 29 216 1.8E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c09430 02060bc9b4d1b4685809d3be5a6eb54f 416 PIRSF PIRSF000521 173 407 2.4E-43 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c09430 02060bc9b4d1b4685809d3be5a6eb54f 416 PIRSF PIRSF000521 31 132 1.4E-10 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c09430 02060bc9b4d1b4685809d3be5a6eb54f 416 PIRSF PIRSF000521 128 160 3.3 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c09430 02060bc9b4d1b4685809d3be5a6eb54f 416 Pfam PF00202 Aminotransferase class-III 34 402 6.0E-118 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c09430 02060bc9b4d1b4685809d3be5a6eb54f 416 Gene3D G3DSA:3.90.1150.10 5 404 5.6E-172 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c09430 02060bc9b4d1b4685809d3be5a6eb54f 416 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 21 407 63.423 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 TSC_c09430 02060bc9b4d1b4685809d3be5a6eb54f 416 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 223 260 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c09430 02060bc9b4d1b4685809d3be5a6eb54f 416 Gene3D G3DSA:3.40.640.10 64 308 5.6E-172 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c09430 02060bc9b4d1b4685809d3be5a6eb54f 416 SUPERFAMILY SSF53383 23 405 1.6E-134 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c23300 9f58b2b6dbd8271a094522cfbdf574e6 358 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 201 357 1.4E-51 T 12-10-2018 IPR000160 GGDEF domain TSC_c23300 9f58b2b6dbd8271a094522cfbdf574e6 358 SMART SM00267 188 358 3.7E-60 T 12-10-2018 IPR000160 GGDEF domain TSC_c23300 9f58b2b6dbd8271a094522cfbdf574e6 358 Pfam PF00990 Diguanylate cyclase, GGDEF domain 201 354 3.1E-46 T 12-10-2018 IPR000160 GGDEF domain TSC_c23300 9f58b2b6dbd8271a094522cfbdf574e6 358 SUPERFAMILY SSF55073 206 356 2.75E-48 T 12-10-2018 IPR029787 Nucleotide cyclase TSC_c23300 9f58b2b6dbd8271a094522cfbdf574e6 358 Gene3D G3DSA:3.30.70.270 189 357 7.4E-57 T 12-10-2018 TSC_c14140 4c271748b13ff8eae0ce6f9e3ae4d1a4 123 Gene3D G3DSA:2.40.40.20 4 122 4.6E-51 T 12-10-2018 TSC_c14140 4c271748b13ff8eae0ce6f9e3ae4d1a4 123 SUPERFAMILY SSF50692 6 120 2.49E-48 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSC_c14140 4c271748b13ff8eae0ce6f9e3ae4d1a4 123 PIRSF PIRSF006246 4 123 6.8E-52 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TSC_c14140 4c271748b13ff8eae0ce6f9e3ae4d1a4 123 Pfam PF02261 Aspartate decarboxylase 6 117 1.3E-49 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TSC_c14140 4c271748b13ff8eae0ce6f9e3ae4d1a4 123 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 123 68.066 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TSC_c14140 4c271748b13ff8eae0ce6f9e3ae4d1a4 123 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 8 93 1.0E-40 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TSC_c14140 4c271748b13ff8eae0ce6f9e3ae4d1a4 123 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 6 120 3.1E-47 T 12-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 TSC_c12990 6a8f9a980969b147e1220a828db0a829 358 PIRSF PIRSF039026 1 354 4.2E-124 T 12-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like TSC_c12990 6a8f9a980969b147e1220a828db0a829 358 Gene3D G3DSA:3.40.190.10 151 321 8.5E-125 T 12-10-2018 TSC_c12990 6a8f9a980969b147e1220a828db0a829 358 Gene3D G3DSA:3.40.190.170 31 335 8.5E-125 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSC_c12990 6a8f9a980969b147e1220a828db0a829 358 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 38 321 3.9E-57 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSC_c12990 6a8f9a980969b147e1220a828db0a829 358 SUPERFAMILY SSF53850 130 267 3.53E-5 T 12-10-2018 TSC_c20940 75d6f84cbaa7009e5a983ffa2b93d529 643 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 313 626 5.0E-44 T 12-10-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal TSC_c20940 75d6f84cbaa7009e5a983ffa2b93d529 643 Pfam PF01578 Cytochrome C assembly protein 90 294 6.9E-31 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 TSC_c20940 75d6f84cbaa7009e5a983ffa2b93d529 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 6.6E-40 T 12-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSC_c20940 75d6f84cbaa7009e5a983ffa2b93d529 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 131 148 6.6E-40 T 12-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSC_c20940 75d6f84cbaa7009e5a983ffa2b93d529 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 243 263 6.6E-40 T 12-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSC_c20940 75d6f84cbaa7009e5a983ffa2b93d529 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 293 309 6.6E-40 T 12-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSC_c20940 75d6f84cbaa7009e5a983ffa2b93d529 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 209 235 6.6E-40 T 12-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSC_c20940 75d6f84cbaa7009e5a983ffa2b93d529 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 81 107 6.6E-40 T 12-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSC_c20940 75d6f84cbaa7009e5a983ffa2b93d529 643 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 273 293 6.6E-40 T 12-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSC_c03940 340c723993f9980625b1ae895d0a4b31 438 Pfam PF00463 Isocitrate lyase family 258 433 9.5E-52 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 TSC_c03940 340c723993f9980625b1ae895d0a4b31 438 Pfam PF00463 Isocitrate lyase family 15 254 3.3E-62 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 TSC_c03940 340c723993f9980625b1ae895d0a4b31 438 ProSitePatterns PS00161 Isocitrate lyase signature. 193 198 - T 12-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 TSC_c03940 340c723993f9980625b1ae895d0a4b31 438 Gene3D G3DSA:3.20.20.60 12 416 8.4E-175 T 12-10-2018 TSC_c03940 340c723993f9980625b1ae895d0a4b31 438 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 15 254 6.0E-102 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 TSC_c03940 340c723993f9980625b1ae895d0a4b31 438 PIRSF PIRSF001362 7 436 6.1E-238 T 12-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 TSC_c03940 340c723993f9980625b1ae895d0a4b31 438 SUPERFAMILY SSF51621 11 433 7.18E-156 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSC_c07060 5ab00675d1408aed30c115507cf27df9 154 Gene3D G3DSA:3.40.50.2020 1 152 7.8E-34 T 12-10-2018 TSC_c07060 5ab00675d1408aed30c115507cf27df9 154 SUPERFAMILY SSF53271 2 147 1.02E-27 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TSC_c07060 5ab00675d1408aed30c115507cf27df9 154 Pfam PF00156 Phosphoribosyl transferase domain 7 147 4.7E-14 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 69 4.6E-14 T 12-10-2018 IPR004176 Clp, N-terminal TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 202 334 8.7E-14 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 SUPERFAMILY SSF52540 156 542 6.45E-101 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 Pfam PF07724 AAA domain (Cdc48 subfamily) 593 758 1.2E-55 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 Gene3D G3DSA:3.40.50.300 341 541 4.3E-80 T 12-10-2018 TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 SMART SM00382 594 736 2.7E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 SMART SM00382 197 341 5.7E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 Gene3D G3DSA:3.40.50.300 546 762 7.5E-90 T 12-10-2018 TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 SUPERFAMILY SSF52540 543 846 7.59E-89 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 7 853 0.0 T 12-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 Gene3D G3DSA:1.10.1780.10 1 147 2.9E-34 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 705 719 1.9E-43 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 643 661 1.9E-43 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 598 616 1.9E-43 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 672 690 1.9E-43 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 Gene3D G3DSA:3.40.50.300 148 340 5.6E-76 T 12-10-2018 TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 SUPERFAMILY SSF81923 4 155 1.28E-33 T 12-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 Gene3D G3DSA:1.10.8.60 764 861 1.8E-33 T 12-10-2018 TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 293 305 - T 12-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 764 844 7.6E-29 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 SMART SM01086 764 853 4.1E-41 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TSC_c20310 9b58f62c14b3cc871caaf5b6310a8356 861 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 628 646 - T 12-10-2018 IPR028299 ClpA/B, conserved site 2 TSC_c09120 fd529aebaedbb25ecead85e90d13262a 860 SUPERFAMILY SSF52540 29 155 9.01E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c09120 fd529aebaedbb25ecead85e90d13262a 860 SUPERFAMILY SSF48452 369 556 9.86E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c09120 fd529aebaedbb25ecead85e90d13262a 860 SMART SM00028 363 396 82.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c09120 fd529aebaedbb25ecead85e90d13262a 860 SMART SM00028 526 559 1.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c01100 003d426b0cb03d521f1b53acb5354126 359 Pfam PF12849 PBP superfamily domain 16 317 1.5E-58 T 12-10-2018 IPR024370 PBP domain TSC_c01100 003d426b0cb03d521f1b53acb5354126 359 SUPERFAMILY SSF53850 25 347 1.49E-88 T 12-10-2018 TSC_c01100 003d426b0cb03d521f1b53acb5354126 359 Gene3D G3DSA:3.40.190.10 28 331 1.5E-107 T 12-10-2018 TSC_c01100 003d426b0cb03d521f1b53acb5354126 359 PIRSF PIRSF002756 2 348 7.6E-108 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 TSC_c01100 003d426b0cb03d521f1b53acb5354126 359 Gene3D G3DSA:3.40.190.10 108 280 1.5E-107 T 12-10-2018 TSC_c01100 003d426b0cb03d521f1b53acb5354126 359 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 27 331 7.4E-113 T 12-10-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 TSC_c15710 4880174e527faec3027e4c00d0096fa1 828 Pfam PF01368 DHH family 3 143 4.8E-8 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TSC_c15710 4880174e527faec3027e4c00d0096fa1 828 Gene3D G3DSA:1.10.3090.10 582 816 1.9E-29 T 12-10-2018 TSC_c15710 4880174e527faec3027e4c00d0096fa1 828 Gene3D G3DSA:3.90.1640.10 2 178 8.6E-26 T 12-10-2018 TSC_c15710 4880174e527faec3027e4c00d0096fa1 828 SUPERFAMILY SSF54631 303 424 1.11E-11 T 12-10-2018 TSC_c15710 4880174e527faec3027e4c00d0096fa1 828 Gene3D G3DSA:3.30.460.10 433 581 2.3E-33 T 12-10-2018 TSC_c15710 4880174e527faec3027e4c00d0096fa1 828 SUPERFAMILY SSF64182 3 283 1.44E-43 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily TSC_c15710 4880174e527faec3027e4c00d0096fa1 828 SUPERFAMILY SSF81891 585 817 2.49E-26 T 12-10-2018 TSC_c15710 4880174e527faec3027e4c00d0096fa1 828 SUPERFAMILY SSF81301 451 583 5.01E-28 T 12-10-2018 TSC_c15710 4880174e527faec3027e4c00d0096fa1 828 Pfam PF01743 Poly A polymerase head domain 460 586 2.3E-22 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 TSC_c15710 4880174e527faec3027e4c00d0096fa1 828 Pfam PF00571 CBS domain 306 361 3.3E-6 T 12-10-2018 IPR000644 CBS domain TSC_c15710 4880174e527faec3027e4c00d0096fa1 828 Pfam PF02272 DHHA1 domain 183 282 4.5E-7 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TSC_c15710 4880174e527faec3027e4c00d0096fa1 828 Gene3D G3DSA:3.10.580.10 302 426 1.0E-9 T 12-10-2018 TSC_c17490 ba550e8ec0de4e42b0dcd3acaa09bec1 170 Pfam PF02613 Nitrate reductase delta subunit 39 120 3.1E-5 T 12-10-2018 IPR020945 DMSO/Nitrate reductase chaperone TSC_c17490 ba550e8ec0de4e42b0dcd3acaa09bec1 170 SUPERFAMILY SSF89155 5 163 3.53E-18 T 12-10-2018 IPR036411 TorD-like superfamily TSC_c01450 09b897e37d46d590afe2f9617b1eb892 268 Pfam PF00582 Universal stress protein family 206 268 5.2E-5 T 12-10-2018 IPR006016 UspA TSC_c01450 09b897e37d46d590afe2f9617b1eb892 268 Pfam PF00582 Universal stress protein family 2 147 5.4E-19 T 12-10-2018 IPR006016 UspA TSC_c01450 09b897e37d46d590afe2f9617b1eb892 268 PRINTS PR01438 Universal stress protein signature 154 172 5.4E-6 T 12-10-2018 IPR006015 Universal stress protein A TSC_c01450 09b897e37d46d590afe2f9617b1eb892 268 PRINTS PR01438 Universal stress protein signature 246 268 5.4E-6 T 12-10-2018 IPR006015 Universal stress protein A TSC_c01450 09b897e37d46d590afe2f9617b1eb892 268 SUPERFAMILY SSF52402 1 151 2.34E-26 T 12-10-2018 TSC_c01450 09b897e37d46d590afe2f9617b1eb892 268 Gene3D G3DSA:3.40.50.12370 1 268 4.5E-87 T 12-10-2018 TSC_c01450 09b897e37d46d590afe2f9617b1eb892 268 SUPERFAMILY SSF52402 158 268 1.34E-16 T 12-10-2018 TSC_c15040 85e187f7d4402cadfd3b5ed1e51205f8 254 Gene3D G3DSA:3.40.190.10 29 247 1.6E-88 T 12-10-2018 TSC_c15040 85e187f7d4402cadfd3b5ed1e51205f8 254 Gene3D G3DSA:3.40.190.10 115 212 1.6E-88 T 12-10-2018 TSC_c15040 85e187f7d4402cadfd3b5ed1e51205f8 254 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 32 249 2.0E-65 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSC_c15040 85e187f7d4402cadfd3b5ed1e51205f8 254 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 54 67 - T 12-10-2018 IPR018313 Solute-binding protein family 3, conserved site TSC_c15040 85e187f7d4402cadfd3b5ed1e51205f8 254 SUPERFAMILY SSF53850 1 250 1.02E-69 T 12-10-2018 TSC_c15040 85e187f7d4402cadfd3b5ed1e51205f8 254 SMART SM00062 31 250 5.2E-67 T 12-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF TSC_c17090 43f0343079a8622901a14917bc422ff0 228 SUPERFAMILY SSF56300 1 210 5.7E-26 T 12-10-2018 TSC_c17090 43f0343079a8622901a14917bc422ff0 228 Pfam PF00149 Calcineurin-like phosphoesterase 1 193 9.3E-10 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSC_c17090 43f0343079a8622901a14917bc422ff0 228 PIRSF PIRSF033094 1 227 6.8E-89 T 12-10-2018 IPR014578 Predicted phosphoesterase, CT488 type TSC_c09290 736cbc7d8b8a0089114b77b298d7c9de 156 Pfam PF03449 Transcription elongation factor, N-terminal 6 74 3.6E-15 T 12-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 TSC_c09290 736cbc7d8b8a0089114b77b298d7c9de 156 SUPERFAMILY SSF54534 80 155 6.41E-16 T 12-10-2018 TSC_c09290 736cbc7d8b8a0089114b77b298d7c9de 156 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 80 155 6.2E-20 T 12-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 TSC_c09290 736cbc7d8b8a0089114b77b298d7c9de 156 Gene3D G3DSA:3.10.50.30 78 151 2.7E-27 T 12-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 TSC_c09290 736cbc7d8b8a0089114b77b298d7c9de 156 SUPERFAMILY SSF46557 4 76 2.75E-13 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 TSC_c09290 736cbc7d8b8a0089114b77b298d7c9de 156 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 120 136 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 TSC_c09290 736cbc7d8b8a0089114b77b298d7c9de 156 PIRSF PIRSF006092 1 156 2.0E-45 T 12-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 TSC_c09290 736cbc7d8b8a0089114b77b298d7c9de 156 Gene3D G3DSA:1.10.287.180 1 77 2.7E-31 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 TSC_c13190 4e77406b3d747f860c8bceac59ef339e 397 PIRSF PIRSF000429 1 396 7.5E-138 T 12-10-2018 IPR002155 Thiolase GO:0016747 TSC_c13190 4e77406b3d747f860c8bceac59ef339e 397 ProSitePatterns PS00737 Thiolases signature 2. 341 357 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 TSC_c13190 4e77406b3d747f860c8bceac59ef339e 397 Gene3D G3DSA:3.40.47.10 6 278 6.5E-153 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c13190 4e77406b3d747f860c8bceac59ef339e 397 SUPERFAMILY SSF53901 273 394 8.38E-43 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c13190 4e77406b3d747f860c8bceac59ef339e 397 ProSitePatterns PS00099 Thiolases active site. 376 389 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 TSC_c13190 4e77406b3d747f860c8bceac59ef339e 397 SUPERFAMILY SSF53901 3 272 2.33E-78 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c13190 4e77406b3d747f860c8bceac59ef339e 397 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 TSC_c13190 4e77406b3d747f860c8bceac59ef339e 397 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 393 3.7E-145 T 12-10-2018 IPR002155 Thiolase GO:0016747 TSC_c13190 4e77406b3d747f860c8bceac59ef339e 397 Gene3D G3DSA:3.40.47.10 129 391 6.5E-153 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c13190 4e77406b3d747f860c8bceac59ef339e 397 Pfam PF02803 Thiolase, C-terminal domain 272 393 2.0E-46 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TSC_c13190 4e77406b3d747f860c8bceac59ef339e 397 Pfam PF00108 Thiolase, N-terminal domain 5 265 4.3E-76 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TSC_c25060 63ff79071f168a569d1e859ec96c1dd5 597 Gene3D G3DSA:3.50.50.60 304 451 1.9E-47 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c25060 63ff79071f168a569d1e859ec96c1dd5 597 Gene3D G3DSA:3.50.50.60 1 213 1.4E-74 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c25060 63ff79071f168a569d1e859ec96c1dd5 597 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 266 280 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 TSC_c25060 63ff79071f168a569d1e859ec96c1dd5 597 Pfam PF01134 Glucose inhibited division protein A 4 390 3.3E-139 T 12-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 TSC_c25060 63ff79071f168a569d1e859ec96c1dd5 597 Pfam PF13932 GidA associated domain 395 589 1.4E-55 T 12-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 TSC_c25060 63ff79071f168a569d1e859ec96c1dd5 597 Gene3D G3DSA:1.10.150.570 542 595 2.3E-17 T 12-10-2018 TSC_c25060 63ff79071f168a569d1e859ec96c1dd5 597 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 3 593 1.6E-201 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 TSC_c25060 63ff79071f168a569d1e859ec96c1dd5 597 Gene3D G3DSA:1.10.10.1800 454 541 3.8E-5 T 12-10-2018 TSC_c25060 63ff79071f168a569d1e859ec96c1dd5 597 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 361 384 - T 12-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 TSC_c25060 63ff79071f168a569d1e859ec96c1dd5 597 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 358 365 7.4E-6 T 12-10-2018 TSC_c25060 63ff79071f168a569d1e859ec96c1dd5 597 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 7.4E-6 T 12-10-2018 TSC_c25060 63ff79071f168a569d1e859ec96c1dd5 597 SUPERFAMILY SSF51905 1 253 4.44E-39 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c25060 63ff79071f168a569d1e859ec96c1dd5 597 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 1 597 36.811 T 12-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 TSC_c25060 63ff79071f168a569d1e859ec96c1dd5 597 SMART SM01228 519 590 3.2E-32 T 12-10-2018 TSC_c06440 711a30a8f67a3599d6769f4889740622 361 Gene3D G3DSA:3.30.930.10 1 306 1.4E-60 T 12-10-2018 TSC_c06440 711a30a8f67a3599d6769f4889740622 361 SUPERFAMILY SSF55681 2 301 8.76E-54 T 12-10-2018 TSC_c06440 711a30a8f67a3599d6769f4889740622 361 Pfam PF13393 Histidyl-tRNA synthetase 5 296 1.7E-71 T 12-10-2018 TSC_c06440 711a30a8f67a3599d6769f4889740622 361 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 12 340 25.445 T 12-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 TSC_c06440 711a30a8f67a3599d6769f4889740622 361 PIRSF PIRSF001549 1 325 1.6E-51 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 TSC_c12110 de13bca115a1613ce9955e0806b569e4 556 TIGRFAM TIGR02510 NrdE-prime: ribonucleoside-diphosphate reductase, alpha chain 2 556 1.0E-288 T 12-10-2018 IPR013350 Ribonucleotide reductase alpha chain TSC_c12110 de13bca115a1613ce9955e0806b569e4 556 SUPERFAMILY SSF51998 83 536 6.1E-109 T 12-10-2018 TSC_c12110 de13bca115a1613ce9955e0806b569e4 556 Pfam PF02867 Ribonucleotide reductase, barrel domain 211 370 1.1E-25 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSC_c12110 de13bca115a1613ce9955e0806b569e4 556 Pfam PF02867 Ribonucleotide reductase, barrel domain 379 533 2.9E-32 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSC_c12110 de13bca115a1613ce9955e0806b569e4 556 Gene3D G3DSA:3.20.70.20 206 543 1.4E-91 T 12-10-2018 TSC_c12110 de13bca115a1613ce9955e0806b569e4 556 Gene3D G3DSA:3.20.70.20 21 205 4.8E-36 T 12-10-2018 TSC_c12110 de13bca115a1613ce9955e0806b569e4 556 Pfam PF02867 Ribonucleotide reductase, barrel domain 85 203 1.9E-22 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSC_c12110 de13bca115a1613ce9955e0806b569e4 556 PRINTS PR01183 Ribonucleotide reductase large chain signature 386 413 2.4E-10 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSC_c12110 de13bca115a1613ce9955e0806b569e4 556 PRINTS PR01183 Ribonucleotide reductase large chain signature 158 177 2.4E-10 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSC_c12110 de13bca115a1613ce9955e0806b569e4 556 PRINTS PR01183 Ribonucleotide reductase large chain signature 325 347 2.4E-10 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSC_c14480 982122142a9042ce4efc782ed445005d 285 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 39 51 6.0E-5 T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSC_c14480 982122142a9042ce4efc782ed445005d 285 ProSitePatterns PS01348 MraY family signature 2. 139 150 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSC_c14480 982122142a9042ce4efc782ed445005d 285 ProSitePatterns PS01347 MraY family signature 1. 39 51 - T 12-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSC_c14480 982122142a9042ce4efc782ed445005d 285 Pfam PF00953 Glycosyl transferase family 4 68 206 1.0E-26 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 TSC_c08070 d1a38ab13f6f4fc8136cf25bf94e19b6 337 Pfam PF01850 PIN domain 144 255 3.5E-5 T 12-10-2018 IPR002716 PIN domain TSC_c08070 d1a38ab13f6f4fc8136cf25bf94e19b6 337 Pfam PF01938 TRAM domain 268 318 3.4E-5 T 12-10-2018 IPR002792 TRAM domain TSC_c08070 d1a38ab13f6f4fc8136cf25bf94e19b6 337 Gene3D G3DSA:3.40.50.1010 140 269 1.1E-44 T 12-10-2018 TSC_c08070 d1a38ab13f6f4fc8136cf25bf94e19b6 337 SUPERFAMILY SSF88723 143 265 4.58E-21 T 12-10-2018 IPR029060 PIN-like domain superfamily TSC_c08070 d1a38ab13f6f4fc8136cf25bf94e19b6 337 SMART SM00670 141 245 6.1E-4 T 12-10-2018 IPR002716 PIN domain TSC_c22000 0b6d70e20cf4dbd8c57a07d61564126f 927 SUPERFAMILY SSF48452 315 740 1.9E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c22000 0b6d70e20cf4dbd8c57a07d61564126f 927 SMART SM00028 519 552 31.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c22000 0b6d70e20cf4dbd8c57a07d61564126f 927 SMART SM00028 715 748 1.3 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c22000 0b6d70e20cf4dbd8c57a07d61564126f 927 SMART SM00028 310 343 0.51 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c22000 0b6d70e20cf4dbd8c57a07d61564126f 927 Gene3D G3DSA:1.25.40.10 676 763 6.3E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c22000 0b6d70e20cf4dbd8c57a07d61564126f 927 Gene3D G3DSA:1.25.40.10 280 420 5.0E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c22000 0b6d70e20cf4dbd8c57a07d61564126f 927 SUPERFAMILY SSF53335 56 246 1.79E-15 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c22000 0b6d70e20cf4dbd8c57a07d61564126f 927 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 816 911 9.7E-8 T 12-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 TSC_c22000 0b6d70e20cf4dbd8c57a07d61564126f 927 Pfam PF13432 Tetratricopeptide repeat 345 401 1.6E-5 T 12-10-2018 TSC_c22000 0b6d70e20cf4dbd8c57a07d61564126f 927 Gene3D G3DSA:3.40.50.150 47 234 1.0E-11 T 12-10-2018 TSC_c22000 0b6d70e20cf4dbd8c57a07d61564126f 927 SUPERFAMILY SSF81901 457 667 7.98E-8 T 12-10-2018 TSC_c22000 0b6d70e20cf4dbd8c57a07d61564126f 927 Gene3D G3DSA:1.25.40.10 447 661 6.2E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c24670 e2981f4423ef6e9b53dff9ee8d33fbb8 390 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 129 141 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSC_c24670 e2981f4423ef6e9b53dff9ee8d33fbb8 390 Gene3D G3DSA:1.10.540.10 7 125 5.0E-34 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSC_c24670 e2981f4423ef6e9b53dff9ee8d33fbb8 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 128 225 3.9E-21 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSC_c24670 e2981f4423ef6e9b53dff9ee8d33fbb8 390 Gene3D G3DSA:1.20.140.10 246 389 8.8E-57 T 12-10-2018 TSC_c24670 e2981f4423ef6e9b53dff9ee8d33fbb8 390 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 345 364 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSC_c24670 e2981f4423ef6e9b53dff9ee8d33fbb8 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 123 1.5E-28 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSC_c24670 e2981f4423ef6e9b53dff9ee8d33fbb8 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 238 387 1.6E-51 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSC_c24670 e2981f4423ef6e9b53dff9ee8d33fbb8 390 Gene3D G3DSA:2.40.110.10 126 245 7.0E-35 T 12-10-2018 TSC_c24670 e2981f4423ef6e9b53dff9ee8d33fbb8 390 SUPERFAMILY SSF56645 8 251 1.02E-69 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSC_c24670 e2981f4423ef6e9b53dff9ee8d33fbb8 390 PIRSF PIRSF016578 9 371 6.1E-30 T 12-10-2018 TSC_c24670 e2981f4423ef6e9b53dff9ee8d33fbb8 390 SUPERFAMILY SSF47203 236 388 4.99E-60 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSC_c22920 130c72a6d319f928c3833d06da0c74b6 204 Pfam PF14332 Domain of unknown function (DUF4388) 5 108 5.6E-8 T 12-10-2018 IPR025497 Domain of unknown function DUF4388 TSC_c22920 130c72a6d319f928c3833d06da0c74b6 204 SUPERFAMILY SSF46785 147 182 9.58E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c24540 fda154784508a068878c962e185d8c91 306 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 5 269 5.6E-36 T 12-10-2018 IPR005218 Diacylglycerol/lipid kinase TSC_c24540 fda154784508a068878c962e185d8c91 306 SUPERFAMILY SSF111331 4 287 1.37E-67 T 12-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily TSC_c24540 fda154784508a068878c962e185d8c91 306 Gene3D G3DSA:3.40.50.10330 2 122 1.6E-29 T 12-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 TSC_c24540 fda154784508a068878c962e185d8c91 306 Gene3D G3DSA:2.60.200.40 123 275 6.2E-36 T 12-10-2018 TSC_c24540 fda154784508a068878c962e185d8c91 306 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 119 3.2E-26 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 TSC_c24540 fda154784508a068878c962e185d8c91 306 SMART SM00046 2 119 3.4E-8 T 12-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 TSC_c18270 5f0a37037481248d38ba449ef12a0b50 314 SUPERFAMILY SSF52283 3 136 7.56E-37 T 12-10-2018 TSC_c18270 5f0a37037481248d38ba449ef12a0b50 314 SUPERFAMILY SSF51735 104 282 2.28E-60 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c18270 5f0a37037481248d38ba449ef12a0b50 314 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 222 238 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TSC_c18270 5f0a37037481248d38ba449ef12a0b50 314 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 150 177 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TSC_c18270 5f0a37037481248d38ba449ef12a0b50 314 Gene3D G3DSA:3.40.50.720 100 281 9.0E-127 T 12-10-2018 TSC_c18270 5f0a37037481248d38ba449ef12a0b50 314 Gene3D G3DSA:3.40.50.720 11 306 9.0E-127 T 12-10-2018 TSC_c18270 5f0a37037481248d38ba449ef12a0b50 314 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 282 1.4E-60 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TSC_c18270 5f0a37037481248d38ba449ef12a0b50 314 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 313 8.8E-38 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TSC_c18270 5f0a37037481248d38ba449ef12a0b50 314 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 193 215 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TSC_c08930 f496b0539ddac04e89499840f19d9b46 220 Pfam PF03315 Serine dehydratase beta chain 10 72 1.7E-12 T 12-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 TSC_c08930 f496b0539ddac04e89499840f19d9b46 220 Gene3D G3DSA:3.30.1330.90 10 131 2.2E-19 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 TSC_c08930 f496b0539ddac04e89499840f19d9b46 220 Gene3D G3DSA:3.30.70.260 144 215 6.7E-15 T 12-10-2018 TSC_c08930 f496b0539ddac04e89499840f19d9b46 220 SUPERFAMILY SSF143548 16 133 2.35E-30 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 TSC_c08930 f496b0539ddac04e89499840f19d9b46 220 SUPERFAMILY SSF55021 134 215 2.7E-15 T 12-10-2018 TSC_c08930 f496b0539ddac04e89499840f19d9b46 220 Pfam PF01842 ACT domain 146 194 7.2E-8 T 12-10-2018 IPR002912 ACT domain TSC_c08930 f496b0539ddac04e89499840f19d9b46 220 PIRSF PIRSF036692 1 217 2.0E-78 T 12-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 TSC_c08930 f496b0539ddac04e89499840f19d9b46 220 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 4 197 3.3E-65 T 12-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 TSC_c20260 01a64c846c8537d92e6f4fc2d75e66b1 627 Pfam PF01434 Peptidase family M41 385 590 8.6E-76 T 12-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 TSC_c20260 01a64c846c8537d92e6f4fc2d75e66b1 627 Gene3D G3DSA:1.10.8.60 326 403 5.4E-32 T 12-10-2018 TSC_c20260 01a64c846c8537d92e6f4fc2d75e66b1 627 SUPERFAMILY SSF52540 148 396 1.01E-75 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c20260 01a64c846c8537d92e6f4fc2d75e66b1 627 ProSitePatterns PS00674 AAA-protein family signature. 295 313 - T 12-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 TSC_c20260 01a64c846c8537d92e6f4fc2d75e66b1 627 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 7 601 37.064 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 TSC_c20260 01a64c846c8537d92e6f4fc2d75e66b1 627 Gene3D G3DSA:3.40.50.300 142 325 5.2E-71 T 12-10-2018 TSC_c20260 01a64c846c8537d92e6f4fc2d75e66b1 627 SMART SM00382 188 327 2.4E-24 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c20260 01a64c846c8537d92e6f4fc2d75e66b1 627 Pfam PF06480 FtsH Extracellular 9 96 1.5E-7 T 12-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 TSC_c20260 01a64c846c8537d92e6f4fc2d75e66b1 627 Gene3D G3DSA:2.40.50.920 28 105 5.9E-7 T 12-10-2018 TSC_c20260 01a64c846c8537d92e6f4fc2d75e66b1 627 Gene3D G3DSA:1.20.58.760 405 600 6.9E-87 T 12-10-2018 TSC_c20260 01a64c846c8537d92e6f4fc2d75e66b1 627 SUPERFAMILY SSF140990 406 599 1.44E-69 T 12-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 TSC_c20260 01a64c846c8537d92e6f4fc2d75e66b1 627 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 192 324 9.4E-44 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSC_c20260 01a64c846c8537d92e6f4fc2d75e66b1 627 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 107 591 4.8E-222 T 12-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 TSC_c11080 ade83d05ebbf6a16572ea004d2dfbbd6 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 217 6.4E-24 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c11080 ade83d05ebbf6a16572ea004d2dfbbd6 220 Gene3D G3DSA:1.10.10.10 125 220 7.3E-28 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c11080 ade83d05ebbf6a16572ea004d2dfbbd6 220 Gene3D G3DSA:3.40.50.2300 1 124 3.6E-31 T 12-10-2018 TSC_c11080 ade83d05ebbf6a16572ea004d2dfbbd6 220 SMART SM00448 3 115 2.3E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c11080 ade83d05ebbf6a16572ea004d2dfbbd6 220 SMART SM00862 147 218 1.3E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c11080 ade83d05ebbf6a16572ea004d2dfbbd6 220 Pfam PF00072 Response regulator receiver domain 6 116 4.2E-19 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c11080 ade83d05ebbf6a16572ea004d2dfbbd6 220 SUPERFAMILY SSF52172 3 176 4.56E-32 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c19990 a104ec9433614ea8a9a26c9c9a6bc575 651 SUPERFAMILY SSF52922 527 651 5.5E-44 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSC_c19990 a104ec9433614ea8a9a26c9c9a6bc575 651 SUPERFAMILY SSF52518 341 520 5.3E-68 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c19990 a104ec9433614ea8a9a26c9c9a6bc575 651 SUPERFAMILY SSF52518 5 323 1.38E-111 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c19990 a104ec9433614ea8a9a26c9c9a6bc575 651 Pfam PF02780 Transketolase, C-terminal domain 533 643 6.7E-10 T 12-10-2018 IPR033248 Transketolase, C-terminal domain TSC_c19990 a104ec9433614ea8a9a26c9c9a6bc575 651 Pfam PF02779 Transketolase, pyrimidine binding domain 348 519 2.1E-47 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSC_c19990 a104ec9433614ea8a9a26c9c9a6bc575 651 Gene3D G3DSA:3.40.50.970 8 328 3.1E-121 T 12-10-2018 TSC_c19990 a104ec9433614ea8a9a26c9c9a6bc575 651 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 10 336 2.3E-146 T 12-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 TSC_c19990 a104ec9433614ea8a9a26c9c9a6bc575 651 Gene3D G3DSA:3.40.50.970 329 530 1.9E-80 T 12-10-2018 TSC_c19990 a104ec9433614ea8a9a26c9c9a6bc575 651 TIGRFAM TIGR00232 tktlase_bact: transketolase 11 650 2.9E-268 T 12-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 TSC_c19990 a104ec9433614ea8a9a26c9c9a6bc575 651 SMART SM00861 349 520 2.5E-71 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSC_c19990 a104ec9433614ea8a9a26c9c9a6bc575 651 Gene3D G3DSA:3.40.50.920 532 651 1.4E-42 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSC_c09160 72c6f0d7d9dee4cb4106bc590dfc2e86 92 Pfam PF04296 Protein of unknown function (DUF448) 8 63 6.7E-19 T 12-10-2018 IPR007393 Domain of unknown function DUF448 TSC_c09160 72c6f0d7d9dee4cb4106bc590dfc2e86 92 Gene3D G3DSA:3.30.1230.10 1 87 3.3E-21 T 12-10-2018 IPR035931 YlxR-like superfamily TSC_c09160 72c6f0d7d9dee4cb4106bc590dfc2e86 92 SUPERFAMILY SSF64376 3 64 2.75E-18 T 12-10-2018 IPR035931 YlxR-like superfamily TSC_c24630 db87ebb4a446743e3fd34a1ff9556582 174 SUPERFAMILY SSF54690 34 167 1.03E-48 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TSC_c24630 db87ebb4a446743e3fd34a1ff9556582 174 Pfam PF02597 ThiS family 1 30 2.5E-8 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TSC_c24630 db87ebb4a446743e3fd34a1ff9556582 174 Gene3D G3DSA:3.90.1170.40 29 166 8.1E-52 T 12-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TSC_c24630 db87ebb4a446743e3fd34a1ff9556582 174 SUPERFAMILY SSF54285 2 30 1.57E-7 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TSC_c24630 db87ebb4a446743e3fd34a1ff9556582 174 Pfam PF02391 MoaE protein 36 147 1.9E-40 T 12-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 TSC_c24630 db87ebb4a446743e3fd34a1ff9556582 174 Gene3D G3DSA:3.10.20.30 1 28 1.6E-9 T 12-10-2018 IPR012675 Beta-grasp domain superfamily TSC_c14870 3c643db3d9e83edd70c10137f25ba982 228 Pfam PF04452 RNA methyltransferase 18 222 6.3E-53 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 TSC_c14870 3c643db3d9e83edd70c10137f25ba982 228 SUPERFAMILY SSF75217 68 222 5.23E-44 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases TSC_c14870 3c643db3d9e83edd70c10137f25ba982 228 SUPERFAMILY SSF88697 4 66 3.48E-30 T 12-10-2018 IPR015947 PUA-like superfamily TSC_c14870 3c643db3d9e83edd70c10137f25ba982 228 Gene3D G3DSA:3.40.1280.10 67 228 2.3E-58 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSC_c14870 3c643db3d9e83edd70c10137f25ba982 228 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 19 222 1.9E-42 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 TSC_c14870 3c643db3d9e83edd70c10137f25ba982 228 Gene3D G3DSA:2.40.240.20 1 66 4.6E-31 T 12-10-2018 TSC_c14870 3c643db3d9e83edd70c10137f25ba982 228 PIRSF PIRSF015601 12 226 2.6E-52 T 12-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 TSC_c12510 ccd53e60fb26026cd7bc06c6b74e73c1 927 SUPERFAMILY SSF52540 285 683 2.2E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c12510 ccd53e60fb26026cd7bc06c6b74e73c1 927 Gene3D G3DSA:1.10.3210.30 1 261 2.4E-68 T 12-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily TSC_c12510 ccd53e60fb26026cd7bc06c6b74e73c1 927 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 21 212 3.1E-20 T 12-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain TSC_c12510 ccd53e60fb26026cd7bc06c6b74e73c1 927 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 284 561 3.1E-30 T 12-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core TSC_c12510 ccd53e60fb26026cd7bc06c6b74e73c1 927 SMART SM00487 260 497 6.1E-4 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSC_c19730 6a63bbc629d8af48214db960a38049fb 343 Pfam PF00107 Zinc-binding dehydrogenase 178 304 5.3E-36 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSC_c19730 6a63bbc629d8af48214db960a38049fb 343 Gene3D G3DSA:3.90.180.10 15 333 9.5E-139 T 12-10-2018 TSC_c19730 6a63bbc629d8af48214db960a38049fb 343 SMART SM00829 10 340 6.9E-21 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSC_c19730 6a63bbc629d8af48214db960a38049fb 343 SUPERFAMILY SSF51735 142 313 2.63E-52 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c19730 6a63bbc629d8af48214db960a38049fb 343 SUPERFAMILY SSF50129 1 171 2.13E-56 T 12-10-2018 IPR011032 GroES-like superfamily TSC_c19730 6a63bbc629d8af48214db960a38049fb 343 Gene3D G3DSA:3.40.50.720 148 290 9.5E-139 T 12-10-2018 TSC_c19730 6a63bbc629d8af48214db960a38049fb 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 134 8.6E-30 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSC_c19140 f5c4ccd4b381ad105527b552640878b5 323 SMART SM00382 38 170 3.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c19140 f5c4ccd4b381ad105527b552640878b5 323 SUPERFAMILY SSF46785 244 318 3.1E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c19140 f5c4ccd4b381ad105527b552640878b5 323 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 323 157.526 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 TSC_c19140 f5c4ccd4b381ad105527b552640878b5 323 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 11 314 2.9E-143 T 12-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 TSC_c19140 f5c4ccd4b381ad105527b552640878b5 323 Gene3D G3DSA:3.40.50.300 5 169 1.8E-43 T 12-10-2018 TSC_c19140 f5c4ccd4b381ad105527b552640878b5 323 Gene3D G3DSA:1.10.10.10 245 323 4.2E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c19140 f5c4ccd4b381ad105527b552640878b5 323 SUPERFAMILY SSF52540 7 238 2.77E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c19140 f5c4ccd4b381ad105527b552640878b5 323 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 242 314 1.0E-31 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 TSC_c19140 f5c4ccd4b381ad105527b552640878b5 323 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 4 223 1.0E-105 T 12-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 TSC_c19140 f5c4ccd4b381ad105527b552640878b5 323 Gene3D G3DSA:1.10.8.60 170 244 8.8E-29 T 12-10-2018 TSC_c19140 f5c4ccd4b381ad105527b552640878b5 323 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 239 314 2.0E-32 T 12-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 TSC_c02130 40fe664c234e33277d989ba7417a5588 133 ProSitePatterns PS01335 Methylglyoxal synthase active site. 63 71 - T 12-10-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 TSC_c02130 40fe664c234e33277d989ba7417a5588 133 PIRSF PIRSF006614 7 132 9.3E-53 T 12-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 TSC_c02130 40fe664c234e33277d989ba7417a5588 133 Gene3D G3DSA:3.40.50.1380 8 133 6.6E-55 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TSC_c02130 40fe664c234e33277d989ba7417a5588 133 Pfam PF02142 MGS-like domain 23 116 2.3E-16 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain TSC_c02130 40fe664c234e33277d989ba7417a5588 133 SUPERFAMILY SSF52335 9 128 7.2E-49 T 12-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily TSC_c02130 40fe664c234e33277d989ba7417a5588 133 SMART SM00851 23 116 1.2E-21 T 12-10-2018 IPR011607 Methylglyoxal synthase-like domain TSC_c02130 40fe664c234e33277d989ba7417a5588 133 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 10 126 2.5E-53 T 12-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 TSC_c02130 40fe664c234e33277d989ba7417a5588 133 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 10 129 32.339 T 12-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 TSC_c22650 7968bd3fed45164cd12e65bc20f4e1df 462 Gene3D G3DSA:3.60.120.10 1 461 1.9E-174 T 12-10-2018 IPR005801 ADC synthase GO:0009058 TSC_c22650 7968bd3fed45164cd12e65bc20f4e1df 462 Pfam PF00425 chorismate binding enzyme 193 447 3.3E-96 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal TSC_c22650 7968bd3fed45164cd12e65bc20f4e1df 462 SUPERFAMILY SSF56322 6 457 1.31E-152 T 12-10-2018 IPR005801 ADC synthase GO:0009058 TSC_c22650 7968bd3fed45164cd12e65bc20f4e1df 462 Pfam PF04715 Anthranilate synthase component I, N terminal region 14 149 9.6E-33 T 12-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSC_c22650 7968bd3fed45164cd12e65bc20f4e1df 462 PRINTS PR00095 Anthranilate synthase component I signature 404 418 1.3E-22 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSC_c22650 7968bd3fed45164cd12e65bc20f4e1df 462 PRINTS PR00095 Anthranilate synthase component I signature 309 322 1.3E-22 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSC_c22650 7968bd3fed45164cd12e65bc20f4e1df 462 PRINTS PR00095 Anthranilate synthase component I signature 295 308 1.3E-22 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSC_c22650 7968bd3fed45164cd12e65bc20f4e1df 462 PRINTS PR00095 Anthranilate synthase component I signature 389 403 1.3E-22 T 12-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSC_c22650 7968bd3fed45164cd12e65bc20f4e1df 462 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 13 455 2.1E-160 T 12-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSC_c24450 062828814df8a5d270386d73400de834 402 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 2 391 6.8E-114 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TSC_c24450 062828814df8a5d270386d73400de834 402 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 1 396 29.974 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TSC_c24450 062828814df8a5d270386d73400de834 402 SUPERFAMILY SSF51717 9 234 1.33E-5 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c24450 062828814df8a5d270386d73400de834 402 Pfam PF04551 GcpE protein 6 392 1.4E-110 T 12-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TSC_c24450 062828814df8a5d270386d73400de834 402 Gene3D G3DSA:3.30.413.10 286 402 1.9E-39 T 12-10-2018 TSC_c24450 062828814df8a5d270386d73400de834 402 PIRSF PIRSF004640 1 402 3.7E-128 T 12-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 TSC_c24450 062828814df8a5d270386d73400de834 402 SUPERFAMILY SSF56014 290 398 4.05E-6 T 12-10-2018 TSC_c24450 062828814df8a5d270386d73400de834 402 Gene3D G3DSA:3.20.20.20 1 285 1.1E-103 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 SUPERFAMILY SSF51905 31 336 2.31E-58 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 Gene3D G3DSA:3.50.50.60 38 328 1.5E-124 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 38 325 1.7E-50 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 38 336 5.9E-119 T 12-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 72 87 5.5E-75 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 138 146 5.5E-75 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 175 199 5.5E-75 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 265 286 5.5E-75 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 299 317 5.5E-75 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 61 5.5E-75 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 93 103 5.5E-75 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 227 243 5.5E-75 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 160 172 5.5E-75 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 Gene3D G3DSA:3.50.50.60 149 271 1.5E-124 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 137 155 1.5E-40 T 12-10-2018 TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 1.5E-40 T 12-10-2018 TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 179 197 1.5E-40 T 12-10-2018 TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 40 59 1.5E-40 T 12-10-2018 TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 279 1.5E-40 T 12-10-2018 TSC_c24260 04cc1628020b09c2b99de214f0ca48c2 345 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 167 187 - T 12-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 TSC_c04340 bac852f7d395599addb5248d67f3967a 458 Gene3D G3DSA:3.30.465.40 6 229 1.8E-70 T 12-10-2018 TSC_c04340 bac852f7d395599addb5248d67f3967a 458 Pfam PF01565 FAD binding domain 38 174 2.3E-36 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TSC_c04340 bac852f7d395599addb5248d67f3967a 458 Pfam PF02913 FAD linked oxidases, C-terminal domain 210 448 1.8E-58 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TSC_c04340 bac852f7d395599addb5248d67f3967a 458 Gene3D G3DSA:1.10.45.10 410 449 4.2E-12 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TSC_c04340 bac852f7d395599addb5248d67f3967a 458 Gene3D G3DSA:3.30.70.2740 331 409 1.2E-10 T 12-10-2018 TSC_c04340 bac852f7d395599addb5248d67f3967a 458 SUPERFAMILY SSF55103 214 453 8.01E-64 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TSC_c04340 bac852f7d395599addb5248d67f3967a 458 SUPERFAMILY SSF56176 4 211 2.38E-65 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSC_c24230 a31d990dd7dc741ef790f804fd83daa5 604 Gene3D G3DSA:3.60.20.10 2 238 9.5E-77 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSC_c24230 a31d990dd7dc741ef790f804fd83daa5 604 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 604 1.3E-254 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TSC_c24230 a31d990dd7dc741ef790f804fd83daa5 604 Gene3D G3DSA:3.40.50.10490 245 603 1.1E-143 T 12-10-2018 TSC_c24230 a31d990dd7dc741ef790f804fd83daa5 604 Gene3D G3DSA:3.40.50.10490 442 589 1.1E-143 T 12-10-2018 TSC_c24230 a31d990dd7dc741ef790f804fd83daa5 604 SUPERFAMILY SSF53697 243 604 7.51E-110 T 12-10-2018 TSC_c24230 a31d990dd7dc741ef790f804fd83daa5 604 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 604 41.972 T 12-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 TSC_c24230 a31d990dd7dc741ef790f804fd83daa5 604 Pfam PF01380 SIS domain 457 586 2.1E-24 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TSC_c24230 a31d990dd7dc741ef790f804fd83daa5 604 Pfam PF01380 SIS domain 289 412 1.0E-25 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TSC_c24230 a31d990dd7dc741ef790f804fd83daa5 604 SUPERFAMILY SSF56235 2 233 8.58E-72 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSC_c24230 a31d990dd7dc741ef790f804fd83daa5 604 Pfam PF13522 Glutamine amidotransferase domain 63 181 4.7E-25 T 12-10-2018 TSC_c06550 a07a6305e615055151cf8217f7e003ae 605 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 16 39 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TSC_c06550 a07a6305e615055151cf8217f7e003ae 605 Gene3D G3DSA:1.10.510.10 100 273 3.9E-49 T 12-10-2018 TSC_c06550 a07a6305e615055151cf8217f7e003ae 605 SUPERFAMILY SSF50998 279 603 1.26E-37 T 12-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily TSC_c06550 a07a6305e615055151cf8217f7e003ae 605 SMART SM00564 388 417 25.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSC_c06550 a07a6305e615055151cf8217f7e003ae 605 SMART SM00564 425 457 0.0049 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSC_c06550 a07a6305e615055151cf8217f7e003ae 605 SMART SM00564 543 574 98.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSC_c06550 a07a6305e615055151cf8217f7e003ae 605 SMART SM00564 505 536 2.0E-5 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSC_c06550 a07a6305e615055151cf8217f7e003ae 605 SMART SM00564 464 496 0.0077 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSC_c06550 a07a6305e615055151cf8217f7e003ae 605 SMART SM00564 350 379 150.0 T 12-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat TSC_c06550 a07a6305e615055151cf8217f7e003ae 605 Gene3D G3DSA:2.130.10.10 288 604 3.7E-46 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TSC_c06550 a07a6305e615055151cf8217f7e003ae 605 Pfam PF00069 Protein kinase domain 10 264 4.8E-48 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TSC_c06550 a07a6305e615055151cf8217f7e003ae 605 Pfam PF13360 PQQ-like domain 350 453 4.2E-9 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TSC_c06550 a07a6305e615055151cf8217f7e003ae 605 Pfam PF13360 PQQ-like domain 467 573 1.4E-13 T 12-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat TSC_c06550 a07a6305e615055151cf8217f7e003ae 605 Gene3D G3DSA:3.30.200.20 1 87 3.3E-27 T 12-10-2018 TSC_c06550 a07a6305e615055151cf8217f7e003ae 605 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 127 139 - T 12-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 TSC_c06550 a07a6305e615055151cf8217f7e003ae 605 SUPERFAMILY SSF56112 4 267 9.58E-74 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TSC_c14800 822159a2c1672e6e68bdba46162a890f 397 Gene3D G3DSA:1.10.10.10 1 75 3.7E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c14800 822159a2c1672e6e68bdba46162a890f 397 Gene3D G3DSA:3.30.420.40 76 197 1.3E-18 T 12-10-2018 TSC_c14800 822159a2c1672e6e68bdba46162a890f 397 Pfam PF00480 ROK family 82 362 4.9E-43 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TSC_c14800 822159a2c1672e6e68bdba46162a890f 397 Pfam PF12802 MarR family 14 58 1.9E-8 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSC_c14800 822159a2c1672e6e68bdba46162a890f 397 ProSitePatterns PS01125 ROK family signature. 201 228 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TSC_c14800 822159a2c1672e6e68bdba46162a890f 397 Gene3D G3DSA:3.30.420.40 198 346 1.1E-36 T 12-10-2018 TSC_c14800 822159a2c1672e6e68bdba46162a890f 397 SUPERFAMILY SSF46785 9 70 1.82E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c14800 822159a2c1672e6e68bdba46162a890f 397 SUPERFAMILY SSF53067 81 366 6.2E-47 T 12-10-2018 TSC_c00840 9601aa13bb36648574e9f5c10b9eb40b 304 SMART SM00382 30 169 9.2E-6 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c00840 9601aa13bb36648574e9f5c10b9eb40b 304 Gene3D G3DSA:3.40.50.300 16 177 7.7E-43 T 12-10-2018 TSC_c00840 9601aa13bb36648574e9f5c10b9eb40b 304 Gene3D G3DSA:1.10.8.300 189 297 3.5E-25 T 12-10-2018 TSC_c00840 9601aa13bb36648574e9f5c10b9eb40b 304 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 33 160 3.3E-56 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 TSC_c00840 9601aa13bb36648574e9f5c10b9eb40b 304 PIRSF PIRSF002849 1 302 8.6E-112 T 12-10-2018 TSC_c00840 9601aa13bb36648574e9f5c10b9eb40b 304 SUPERFAMILY SSF52540 8 273 1.48E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c22140 b054a6111ffaddf1ca9c8fdf8b2ee7f1 277 SUPERFAMILY SSF103481 183 276 2.09E-14 T 12-10-2018 TSC_c22140 b054a6111ffaddf1ca9c8fdf8b2ee7f1 277 SUPERFAMILY SSF103481 39 138 1.12E-13 T 12-10-2018 TSC_c22140 b054a6111ffaddf1ca9c8fdf8b2ee7f1 277 Pfam PF00892 EamA-like transporter family 1 133 1.3E-19 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSC_c22140 b054a6111ffaddf1ca9c8fdf8b2ee7f1 277 Pfam PF00892 EamA-like transporter family 147 275 3.5E-20 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSC_c09220 bf0d818020f338ee468c58b785ea9c71 691 Pfam PF00092 von Willebrand factor type A domain 294 454 7.8E-15 T 12-10-2018 IPR002035 von Willebrand factor, type A TSC_c09220 bf0d818020f338ee468c58b785ea9c71 691 Gene3D G3DSA:3.40.50.410 291 459 1.5E-35 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSC_c09220 bf0d818020f338ee468c58b785ea9c71 691 SUPERFAMILY SSF52317 208 554 1.51E-17 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c09220 bf0d818020f338ee468c58b785ea9c71 691 SUPERFAMILY SSF53300 292 456 5.56E-28 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSC_c09220 bf0d818020f338ee468c58b785ea9c71 691 SMART SM00327 291 463 2.9E-21 T 12-10-2018 IPR002035 von Willebrand factor, type A TSC_c12250 00ed37686e6fc4327bdc00f66556d38a 79 SUPERFAMILY SSF47598 1 42 2.13E-7 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TSC_c12250 00ed37686e6fc4327bdc00f66556d38a 79 Pfam PF01402 Ribbon-helix-helix protein, copG family 3 39 5.3E-9 T 12-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TSC_c02140 d1b033ee398d9ce19341f5cbd5f5a8b9 494 Pfam PF01078 Magnesium chelatase, subunit ChlI 188 392 1.1E-95 T 12-10-2018 IPR000523 Magnesium chelatase ChlI domain TSC_c02140 d1b033ee398d9ce19341f5cbd5f5a8b9 494 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 7 491 7.3E-173 T 12-10-2018 IPR004482 Mg chelatase-related protein TSC_c02140 d1b033ee398d9ce19341f5cbd5f5a8b9 494 Gene3D G3DSA:3.40.50.300 178 494 4.8E-61 T 12-10-2018 TSC_c02140 d1b033ee398d9ce19341f5cbd5f5a8b9 494 Gene3D G3DSA:3.30.230.10 28 168 1.7E-8 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSC_c02140 d1b033ee398d9ce19341f5cbd5f5a8b9 494 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 207 222 4.5E-5 T 12-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TSC_c02140 d1b033ee398d9ce19341f5cbd5f5a8b9 494 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 314 327 4.5E-5 T 12-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TSC_c02140 d1b033ee398d9ce19341f5cbd5f5a8b9 494 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 286 300 4.5E-5 T 12-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TSC_c02140 d1b033ee398d9ce19341f5cbd5f5a8b9 494 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 338 350 4.5E-5 T 12-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 TSC_c02140 d1b033ee398d9ce19341f5cbd5f5a8b9 494 Pfam PF13541 Subunit ChlI of Mg-chelatase 20 140 7.9E-41 T 12-10-2018 TSC_c02140 d1b033ee398d9ce19341f5cbd5f5a8b9 494 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 399 491 1.6E-29 T 12-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain TSC_c02140 d1b033ee398d9ce19341f5cbd5f5a8b9 494 SUPERFAMILY SSF52540 188 491 5.75E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c02140 d1b033ee398d9ce19341f5cbd5f5a8b9 494 SUPERFAMILY SSF54211 7 169 2.24E-36 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c02140 d1b033ee398d9ce19341f5cbd5f5a8b9 494 SMART SM00382 208 389 2.0E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c18670 fb2b04eaa0cc3b219a3dc31912bf9d4a 349 SUPERFAMILY SSF50156 222 341 5.78E-19 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 TSC_c18670 fb2b04eaa0cc3b219a3dc31912bf9d4a 349 PRINTS PR00834 HtrA/DegQ protease family signature 84 104 7.9E-24 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c18670 fb2b04eaa0cc3b219a3dc31912bf9d4a 349 PRINTS PR00834 HtrA/DegQ protease family signature 127 151 7.9E-24 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c18670 fb2b04eaa0cc3b219a3dc31912bf9d4a 349 PRINTS PR00834 HtrA/DegQ protease family signature 190 207 7.9E-24 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c18670 fb2b04eaa0cc3b219a3dc31912bf9d4a 349 PRINTS PR00834 HtrA/DegQ protease family signature 291 303 7.9E-24 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c18670 fb2b04eaa0cc3b219a3dc31912bf9d4a 349 PRINTS PR00834 HtrA/DegQ protease family signature 63 75 7.9E-24 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c18670 fb2b04eaa0cc3b219a3dc31912bf9d4a 349 PRINTS PR00834 HtrA/DegQ protease family signature 168 185 7.9E-24 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c18670 fb2b04eaa0cc3b219a3dc31912bf9d4a 349 SMART SM00228 236 333 5.3E-13 T 12-10-2018 IPR001478 PDZ domain GO:0005515 TSC_c18670 fb2b04eaa0cc3b219a3dc31912bf9d4a 349 Gene3D G3DSA:2.40.10.120 18 232 4.1E-41 T 12-10-2018 TSC_c18670 fb2b04eaa0cc3b219a3dc31912bf9d4a 349 Pfam PF13180 PDZ domain 237 341 9.4E-17 T 12-10-2018 IPR001478 PDZ domain GO:0005515 TSC_c18670 fb2b04eaa0cc3b219a3dc31912bf9d4a 349 Gene3D G3DSA:2.30.42.10 246 349 3.8E-27 T 12-10-2018 TSC_c18670 fb2b04eaa0cc3b219a3dc31912bf9d4a 349 Pfam PF13365 Trypsin-like peptidase domain 55 197 1.6E-22 T 12-10-2018 TSC_c18670 fb2b04eaa0cc3b219a3dc31912bf9d4a 349 SUPERFAMILY SSF50494 3 245 1.08E-43 T 12-10-2018 IPR009003 Peptidase S1, PA clan TSC_c20070 d3c3dd29d6aa5cba1b73a6d1dc0f0d5e 121 SUPERFAMILY SSF88697 4 113 4.64E-28 T 12-10-2018 IPR015947 PUA-like superfamily TSC_c20070 d3c3dd29d6aa5cba1b73a6d1dc0f0d5e 121 Pfam PF04266 ASCH domain 10 99 1.7E-8 T 12-10-2018 IPR007374 ASCH domain TSC_c20070 d3c3dd29d6aa5cba1b73a6d1dc0f0d5e 121 SMART SM01022 8 96 4.6E-4 T 12-10-2018 IPR007374 ASCH domain TSC_c20070 d3c3dd29d6aa5cba1b73a6d1dc0f0d5e 121 Gene3D G3DSA:2.30.130.30 5 104 2.2E-36 T 12-10-2018 TSC_c08400 48c5bddd26f26783b36cd063a0cc11d2 170 Gene3D G3DSA:3.30.70.1150 82 163 2.9E-30 T 12-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal TSC_c08400 48c5bddd26f26783b36cd063a0cc11d2 170 SUPERFAMILY SSF55021 2 76 5.46E-20 T 12-10-2018 TSC_c08400 48c5bddd26f26783b36cd063a0cc11d2 170 SUPERFAMILY SSF55021 78 162 6.41E-27 T 12-10-2018 TSC_c08400 48c5bddd26f26783b36cd063a0cc11d2 170 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 75 5.0E-34 T 12-10-2018 TSC_c08400 48c5bddd26f26783b36cd063a0cc11d2 170 Pfam PF13710 ACT domain 12 73 6.6E-15 T 12-10-2018 TSC_c08400 48c5bddd26f26783b36cd063a0cc11d2 170 Gene3D G3DSA:3.30.70.260 1 78 7.8E-33 T 12-10-2018 TSC_c08400 48c5bddd26f26783b36cd063a0cc11d2 170 Pfam PF10369 Small subunit of acetolactate synthase 83 157 8.9E-29 T 12-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 TSC_c08400 48c5bddd26f26783b36cd063a0cc11d2 170 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 2 158 9.1E-60 T 12-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 TSC_c20870 5f2b4e2d1e0a9baaa7b3f7dfa6ba6357 97 Gene3D G3DSA:1.20.58.110 1 97 2.5E-29 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c20870 5f2b4e2d1e0a9baaa7b3f7dfa6ba6357 97 SUPERFAMILY SSF46992 10 91 9.29E-24 T 12-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c20870 5f2b4e2d1e0a9baaa7b3f7dfa6ba6357 97 TIGRFAM TIGR00029 S20: ribosomal protein bS20 9 90 5.2E-19 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c20870 5f2b4e2d1e0a9baaa7b3f7dfa6ba6357 97 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 16 97 2.0E-31 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c20870 5f2b4e2d1e0a9baaa7b3f7dfa6ba6357 97 Pfam PF01649 Ribosomal protein S20 11 88 5.0E-20 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c20870 5f2b4e2d1e0a9baaa7b3f7dfa6ba6357 97 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 90 15.626 T 12-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c06010 a658405817e4995ea1a7c6d54bfff52d 181 SUPERFAMILY SSF52833 7 168 9.69E-53 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TSC_c06010 a658405817e4995ea1a7c6d54bfff52d 181 Gene3D G3DSA:1.10.10.1590 1 74 3.6E-30 T 12-10-2018 TSC_c06010 a658405817e4995ea1a7c6d54bfff52d 181 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 114 132 - T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06010 a658405817e4995ea1a7c6d54bfff52d 181 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 11 157 2.9E-56 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06010 a658405817e4995ea1a7c6d54bfff52d 181 PIRSF PIRSF000216 1 180 3.3E-66 T 12-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06010 a658405817e4995ea1a7c6d54bfff52d 181 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 12 157 8.8E-50 T 12-10-2018 TSC_c06010 a658405817e4995ea1a7c6d54bfff52d 181 Gene3D G3DSA:3.40.30.10 75 181 6.5E-36 T 12-10-2018 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 3.7E-38 T 12-10-2018 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 255 271 3.7E-38 T 12-10-2018 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 284 306 3.7E-38 T 12-10-2018 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.7E-38 T 12-10-2018 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 3.7E-38 T 12-10-2018 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.9E-74 T 12-10-2018 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.9E-74 T 12-10-2018 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 2.9E-74 T 12-10-2018 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 256 270 2.9E-74 T 12-10-2018 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 421 441 2.9E-74 T 12-10-2018 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 2.9E-74 T 12-10-2018 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 299 306 2.9E-74 T 12-10-2018 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 355 2.9E-74 T 12-10-2018 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 399 414 2.9E-74 T 12-10-2018 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 PIRSF PIRSF000350 1 456 1.6E-95 T 12-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 SUPERFAMILY SSF51905 2 357 1.79E-67 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 338 447 7.2E-37 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 Gene3D G3DSA:3.30.390.30 337 457 5.7E-48 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 SUPERFAMILY SSF55424 335 456 1.65E-41 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 12-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 Gene3D G3DSA:3.50.50.60 144 262 3.6E-128 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 Gene3D G3DSA:3.50.50.60 4 322 3.6E-128 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 319 1.4E-75 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSC_c02700 56735fcfa1b1459d679f021bbf7c8834 457 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 3 457 3.7E-162 T 12-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 TSC_c08640 aaa73961f2a189027a8458fc0f5d435f 495 PRINTS PR01806 Virulence factor MviN signature 49 65 2.7E-27 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSC_c08640 aaa73961f2a189027a8458fc0f5d435f 495 PRINTS PR01806 Virulence factor MviN signature 30 49 2.7E-27 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSC_c08640 aaa73961f2a189027a8458fc0f5d435f 495 PRINTS PR01806 Virulence factor MviN signature 391 408 2.7E-27 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSC_c08640 aaa73961f2a189027a8458fc0f5d435f 495 PRINTS PR01806 Virulence factor MviN signature 245 271 2.7E-27 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSC_c08640 aaa73961f2a189027a8458fc0f5d435f 495 PRINTS PR01806 Virulence factor MviN signature 340 359 2.7E-27 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSC_c08640 aaa73961f2a189027a8458fc0f5d435f 495 PRINTS PR01806 Virulence factor MviN signature 128 152 2.7E-27 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSC_c08640 aaa73961f2a189027a8458fc0f5d435f 495 PRINTS PR01806 Virulence factor MviN signature 152 173 2.7E-27 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSC_c08640 aaa73961f2a189027a8458fc0f5d435f 495 Pfam PF03023 MviN-like protein 29 450 4.1E-68 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSC_c08640 aaa73961f2a189027a8458fc0f5d435f 495 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 2 483 7.6E-80 T 12-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ TSC_c21760 42db7d63e2b1a25b569fe726074c7825 436 SMART SM00998 357 435 4.4E-31 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSC_c21760 42db7d63e2b1a25b569fe726074c7825 436 PRINTS PR00149 Fumarate lyase superfamily signature 269 285 2.4E-22 T 12-10-2018 IPR000362 Fumarate lyase family TSC_c21760 42db7d63e2b1a25b569fe726074c7825 436 PRINTS PR00149 Fumarate lyase superfamily signature 141 159 2.4E-22 T 12-10-2018 IPR000362 Fumarate lyase family TSC_c21760 42db7d63e2b1a25b569fe726074c7825 436 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 2.4E-22 T 12-10-2018 IPR000362 Fumarate lyase family TSC_c21760 42db7d63e2b1a25b569fe726074c7825 436 PRINTS PR00149 Fumarate lyase superfamily signature 224 251 2.4E-22 T 12-10-2018 IPR000362 Fumarate lyase family TSC_c21760 42db7d63e2b1a25b569fe726074c7825 436 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 2 434 2.5E-135 T 12-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSC_c21760 42db7d63e2b1a25b569fe726074c7825 436 SUPERFAMILY SSF48557 3 433 2.2E-120 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 TSC_c21760 42db7d63e2b1a25b569fe726074c7825 436 Gene3D G3DSA:1.20.200.10 101 356 2.4E-90 T 12-10-2018 TSC_c21760 42db7d63e2b1a25b569fe726074c7825 436 ProSitePatterns PS00163 Fumarate lyases signature. 269 278 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TSC_c21760 42db7d63e2b1a25b569fe726074c7825 436 Gene3D G3DSA:1.10.275.10 1 100 2.7E-24 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal TSC_c21760 42db7d63e2b1a25b569fe726074c7825 436 Gene3D G3DSA:1.10.40.30 357 436 1.2E-25 T 12-10-2018 TSC_c21760 42db7d63e2b1a25b569fe726074c7825 436 PRINTS PR00145 Argininosuccinate lyase family signature 224 248 9.5E-5 T 12-10-2018 TSC_c21760 42db7d63e2b1a25b569fe726074c7825 436 PRINTS PR00145 Argininosuccinate lyase family signature 269 285 9.5E-5 T 12-10-2018 TSC_c21760 42db7d63e2b1a25b569fe726074c7825 436 Pfam PF00206 Lyase 6 290 1.8E-48 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal TSC_c21760 42db7d63e2b1a25b569fe726074c7825 436 Pfam PF10397 Adenylosuccinate lyase C-terminus 358 434 2.6E-21 T 12-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSC_c00140 c56f68cc4e3c205a33ce5eba574d5f3b 277 SUPERFAMILY SSF52402 140 272 2.76E-14 T 12-10-2018 TSC_c00140 c56f68cc4e3c205a33ce5eba574d5f3b 277 PRINTS PR01438 Universal stress protein signature 233 245 4.3E-7 T 12-10-2018 IPR006015 Universal stress protein A TSC_c00140 c56f68cc4e3c205a33ce5eba574d5f3b 277 PRINTS PR01438 Universal stress protein signature 139 157 4.3E-7 T 12-10-2018 IPR006015 Universal stress protein A TSC_c00140 c56f68cc4e3c205a33ce5eba574d5f3b 277 PRINTS PR01438 Universal stress protein signature 250 272 4.3E-7 T 12-10-2018 IPR006015 Universal stress protein A TSC_c00140 c56f68cc4e3c205a33ce5eba574d5f3b 277 Pfam PF00582 Universal stress protein family 139 272 1.1E-13 T 12-10-2018 IPR006016 UspA TSC_c00140 c56f68cc4e3c205a33ce5eba574d5f3b 277 Pfam PF00582 Universal stress protein family 2 132 1.2E-6 T 12-10-2018 IPR006016 UspA TSC_c00140 c56f68cc4e3c205a33ce5eba574d5f3b 277 SUPERFAMILY SSF52402 2 133 5.36E-12 T 12-10-2018 TSC_c00140 c56f68cc4e3c205a33ce5eba574d5f3b 277 Gene3D G3DSA:3.40.50.620 135 271 2.6E-15 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c00140 c56f68cc4e3c205a33ce5eba574d5f3b 277 Gene3D G3DSA:3.40.50.620 1 134 2.9E-11 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c14260 0c2038e773738d2435e520af873759de 109 Pfam PF12840 Helix-turn-helix domain 10 69 1.2E-15 T 12-10-2018 TSC_c14260 0c2038e773738d2435e520af873759de 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 3.5E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c14260 0c2038e773738d2435e520af873759de 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 3.5E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c14260 0c2038e773738d2435e520af873759de 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 3.5E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c14260 0c2038e773738d2435e520af873759de 109 SUPERFAMILY SSF46785 10 104 2.79E-25 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c14260 0c2038e773738d2435e520af873759de 109 Gene3D G3DSA:1.10.10.10 4 102 4.5E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c14260 0c2038e773738d2435e520af873759de 109 SMART SM00418 11 89 2.0E-25 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c22030 0734e507c40f7c2225b0fa007f59f566 296 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 201 217 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TSC_c22030 0734e507c40f7c2225b0fa007f59f566 296 SUPERFAMILY SSF51735 86 262 8.47E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c22030 0734e507c40f7c2225b0fa007f59f566 296 Gene3D G3DSA:3.40.50.720 86 268 3.4E-79 T 12-10-2018 TSC_c22030 0734e507c40f7c2225b0fa007f59f566 296 Gene3D G3DSA:3.40.50.720 52 296 3.4E-79 T 12-10-2018 TSC_c22030 0734e507c40f7c2225b0fa007f59f566 296 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 95 261 2.3E-49 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TSC_c08700 9f9a4ade3002e3d4cb40b491ea4e10ba 69 Gene3D G3DSA:3.10.20.570 1 69 1.7E-35 T 12-10-2018 TSC_c08700 9f9a4ade3002e3d4cb40b491ea4e10ba 69 Pfam PF11609 Protein of unknown function (DUF3248) 6 68 2.6E-33 T 12-10-2018 IPR021650 Protein of unknown function DUF3248 TSC_c23900 99b0c6d95268511d7f4678448ec719c0 238 Pfam PF00588 SpoU rRNA Methylase family 89 229 1.8E-38 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TSC_c23900 99b0c6d95268511d7f4678448ec719c0 238 SMART SM00967 2 72 5.3E-17 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TSC_c23900 99b0c6d95268511d7f4678448ec719c0 238 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 3 231 1.0E-62 T 12-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 TSC_c23900 99b0c6d95268511d7f4678448ec719c0 238 Gene3D G3DSA:3.30.1330.30 1 68 1.4E-5 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like TSC_c23900 99b0c6d95268511d7f4678448ec719c0 238 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 2 71 1.8E-16 T 12-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 TSC_c23900 99b0c6d95268511d7f4678448ec719c0 238 SUPERFAMILY SSF75217 60 234 3.99E-43 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases TSC_c23900 99b0c6d95268511d7f4678448ec719c0 238 Gene3D G3DSA:3.40.1280.10 75 235 2.4E-52 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSC_c23900 99b0c6d95268511d7f4678448ec719c0 238 SUPERFAMILY SSF55315 1 68 4.04E-13 T 12-10-2018 IPR029064 50S ribosomal protein L30e-like TSC_c06850 d993041731f7d808baeebfb0fce5145b 576 Pfam PF00390 Malic enzyme, N-terminal domain 89 269 2.0E-71 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TSC_c06850 d993041731f7d808baeebfb0fce5145b 576 SMART SM00919 279 536 2.6E-118 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TSC_c06850 d993041731f7d808baeebfb0fce5145b 576 SMART SM01274 89 269 7.3E-94 T 12-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 TSC_c06850 d993041731f7d808baeebfb0fce5145b 576 Gene3D G3DSA:3.40.50.10380 23 276 1.0E-102 T 12-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 TSC_c06850 d993041731f7d808baeebfb0fce5145b 576 SUPERFAMILY SSF53223 8 278 4.53E-101 T 12-10-2018 TSC_c06850 d993041731f7d808baeebfb0fce5145b 576 SUPERFAMILY SSF51735 279 572 2.09E-84 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c06850 d993041731f7d808baeebfb0fce5145b 576 PRINTS PR00072 Malic enzyme signature 415 431 5.2E-71 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TSC_c06850 d993041731f7d808baeebfb0fce5145b 576 PRINTS PR00072 Malic enzyme signature 95 119 5.2E-71 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TSC_c06850 d993041731f7d808baeebfb0fce5145b 576 PRINTS PR00072 Malic enzyme signature 250 268 5.2E-71 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TSC_c06850 d993041731f7d808baeebfb0fce5145b 576 PRINTS PR00072 Malic enzyme signature 275 291 5.2E-71 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TSC_c06850 d993041731f7d808baeebfb0fce5145b 576 PRINTS PR00072 Malic enzyme signature 191 213 5.2E-71 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TSC_c06850 d993041731f7d808baeebfb0fce5145b 576 PRINTS PR00072 Malic enzyme signature 306 322 5.2E-71 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TSC_c06850 d993041731f7d808baeebfb0fce5145b 576 PRINTS PR00072 Malic enzyme signature 155 184 5.2E-71 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TSC_c06850 d993041731f7d808baeebfb0fce5145b 576 Gene3D G3DSA:3.40.50.720 277 574 2.9E-101 T 12-10-2018 TSC_c06850 d993041731f7d808baeebfb0fce5145b 576 Pfam PF03949 Malic enzyme, NAD binding domain 279 535 1.3E-90 T 12-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 TSC_c06850 d993041731f7d808baeebfb0fce5145b 576 ProSitePatterns PS00331 Malic enzymes signature. 275 291 - T 12-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 TSC_c06850 d993041731f7d808baeebfb0fce5145b 576 PIRSF PIRSF000106 3 573 3.6E-211 T 12-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 TSC_c01590 afa27319faa9d1a7d618e5e69bfc3cef 157 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 10 155 30.073 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSC_c01590 afa27319faa9d1a7d618e5e69bfc3cef 157 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 15 152 1.5E-50 T 12-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSC_c01590 afa27319faa9d1a7d618e5e69bfc3cef 157 SUPERFAMILY SSF52121 6 155 4.84E-56 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSC_c01590 afa27319faa9d1a7d618e5e69bfc3cef 157 Gene3D G3DSA:3.40.50.960 4 156 1.6E-54 T 12-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSC_c01590 afa27319faa9d1a7d618e5e69bfc3cef 157 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 15 151 2.1E-50 T 12-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSC_c08290 a20fc5e173daffd0efb2dbfc1adeaa7d 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 6.1E-9 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TSC_c08290 a20fc5e173daffd0efb2dbfc1adeaa7d 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 6.1E-9 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TSC_c08290 a20fc5e173daffd0efb2dbfc1adeaa7d 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 6.1E-9 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TSC_c08290 a20fc5e173daffd0efb2dbfc1adeaa7d 65 SUPERFAMILY SSF143034 2 64 5.49E-20 T 12-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c08290 a20fc5e173daffd0efb2dbfc1adeaa7d 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 12-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c08290 a20fc5e173daffd0efb2dbfc1adeaa7d 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 64 2.3E-22 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TSC_c08290 a20fc5e173daffd0efb2dbfc1adeaa7d 65 Pfam PF01632 Ribosomal protein L35 2 62 6.2E-21 T 12-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c08290 a20fc5e173daffd0efb2dbfc1adeaa7d 65 Gene3D G3DSA:2.40.50.530 1 65 1.1E-28 T 12-10-2018 TSC_c08290 a20fc5e173daffd0efb2dbfc1adeaa7d 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 15.812 T 12-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 TSC_c15210 40eda5feb0f139791ecb8dbc00d52675 227 PIRSF PIRSF001357 1 226 5.2E-67 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSC_c15210 40eda5feb0f139791ecb8dbc00d52675 227 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 223 32.908 T 12-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 TSC_c15210 40eda5feb0f139791ecb8dbc00d52675 227 SMART SM01133 2 221 1.3E-78 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSC_c15210 40eda5feb0f139791ecb8dbc00d52675 227 Pfam PF01791 DeoC/LacD family aldolase 10 217 1.7E-15 T 12-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSC_c15210 40eda5feb0f139791ecb8dbc00d52675 227 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 219 2.5E-62 T 12-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 TSC_c15210 40eda5feb0f139791ecb8dbc00d52675 227 SUPERFAMILY SSF51569 1 221 2.51E-69 T 12-10-2018 TSC_c15210 40eda5feb0f139791ecb8dbc00d52675 227 Gene3D G3DSA:3.20.20.70 1 227 2.1E-84 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c17860 a92b622027f1d0e3d6067f52da1786fc 445 Gene3D G3DSA:3.90.226.10 194 363 1.0E-89 T 12-10-2018 TSC_c17860 a92b622027f1d0e3d6067f52da1786fc 445 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 52 371 2.8E-84 T 12-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 TSC_c17860 a92b622027f1d0e3d6067f52da1786fc 445 SMART SM00228 103 177 1.1E-16 T 12-10-2018 IPR001478 PDZ domain GO:0005515 TSC_c17860 a92b622027f1d0e3d6067f52da1786fc 445 Pfam PF03572 Peptidase family S41 203 365 4.2E-52 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 TSC_c17860 a92b622027f1d0e3d6067f52da1786fc 445 SUPERFAMILY SSF50156 80 198 4.73E-23 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 TSC_c17860 a92b622027f1d0e3d6067f52da1786fc 445 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 104 173 1.9E-12 T 12-10-2018 IPR001478 PDZ domain GO:0005515 TSC_c17860 a92b622027f1d0e3d6067f52da1786fc 445 SMART SM00245 179 366 2.2E-54 T 12-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 TSC_c17860 a92b622027f1d0e3d6067f52da1786fc 445 Gene3D G3DSA:2.30.42.10 103 193 1.0E-89 T 12-10-2018 TSC_c17860 a92b622027f1d0e3d6067f52da1786fc 445 SUPERFAMILY SSF52096 46 370 4.97E-66 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSC_c17860 a92b622027f1d0e3d6067f52da1786fc 445 Gene3D G3DSA:3.30.750.44 46 341 1.0E-89 T 12-10-2018 TSC_c03160 013d9a54f805161260dd10961595af25 381 Pfam PF00437 Type II/IV secretion system protein 31 279 1.2E-42 T 12-10-2018 IPR001482 Type II/IV secretion system protein TSC_c03160 013d9a54f805161260dd10961595af25 381 Gene3D G3DSA:3.40.50.300 123 381 1.6E-93 T 12-10-2018 TSC_c03160 013d9a54f805161260dd10961595af25 381 Gene3D G3DSA:3.30.450.90 15 122 1.3E-40 T 12-10-2018 TSC_c03160 013d9a54f805161260dd10961595af25 381 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 216 230 - T 12-10-2018 IPR001482 Type II/IV secretion system protein TSC_c03160 013d9a54f805161260dd10961595af25 381 SMART SM00382 145 270 0.0078 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c03160 013d9a54f805161260dd10961595af25 381 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 25 368 2.4E-152 T 12-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 TSC_c03160 013d9a54f805161260dd10961595af25 381 SUPERFAMILY SSF52540 27 360 2.54E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c23880 50d79a78248159a2e28ea8c18225147d 171 Pfam PF03641 Possible lysine decarboxylase 45 163 1.6E-11 T 12-10-2018 IPR031100 LOG family TSC_c23880 50d79a78248159a2e28ea8c18225147d 171 SUPERFAMILY SSF102405 1 169 7.17E-31 T 12-10-2018 TSC_c23880 50d79a78248159a2e28ea8c18225147d 171 Gene3D G3DSA:3.40.50.450 1 171 2.3E-56 T 12-10-2018 TSC_c22250 70fafab65cf5f75941680e4ebc0b6119 160 ProSitePatterns PS00475 Ribosomal protein L15 signature. 113 142 - T 12-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22250 70fafab65cf5f75941680e4ebc0b6119 160 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 148 19.714 T 12-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 TSC_c22250 70fafab65cf5f75941680e4ebc0b6119 160 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 144 4.3E-34 T 12-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22250 70fafab65cf5f75941680e4ebc0b6119 160 Gene3D G3DSA:3.100.10.10 72 149 6.8E-25 T 12-10-2018 TSC_c22250 70fafab65cf5f75941680e4ebc0b6119 160 SUPERFAMILY SSF52080 5 147 8.63E-40 T 12-10-2018 IPR036227 Ribosomal L18e/L15P superfamily TSC_c22250 70fafab65cf5f75941680e4ebc0b6119 160 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 27 146 1.9E-26 T 12-10-2018 IPR021131 Ribosomal protein L18e/L15P TSC_c20050 ce2b0f673e71565fb038679bcef74746 384 SUPERFAMILY SSF103473 12 376 8.76E-36 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c20050 ce2b0f673e71565fb038679bcef74746 384 Gene3D G3DSA:1.20.1250.20 10 195 4.4E-16 T 12-10-2018 TSC_c20050 ce2b0f673e71565fb038679bcef74746 384 Gene3D G3DSA:1.20.1250.20 196 384 2.1E-13 T 12-10-2018 TSC_c20050 ce2b0f673e71565fb038679bcef74746 384 Pfam PF07690 Major Facilitator Superfamily 13 315 1.7E-20 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 Gene3D G3DSA:1.20.210.10 1 533 2.2E-208 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 Pfam PF00510 Cytochrome c oxidase subunit III 550 791 2.1E-25 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 Gene3D G3DSA:1.10.287.70 534 607 5.0E-43 T 12-10-2018 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 193 212 1.2E-83 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 17 42 1.2E-83 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 92 116 1.2E-83 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 427 448 1.2E-83 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 135 147 1.2E-83 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 244 265 1.2E-83 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 64 87 1.2E-83 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 164 182 1.2E-83 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 290 305 1.2E-83 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 314 335 1.2E-83 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 349 367 1.2E-83 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 PRINTS PR01165 Cytochrome c oxidase subunit I signature 377 396 1.2E-83 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 SUPERFAMILY SSF81442 15 519 1.57E-166 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 SUPERFAMILY SSF81452 547 791 1.15E-58 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 26 472 3.9E-139 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 19 519 9.3E-207 T 12-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 Gene3D G3DSA:1.20.120.80 608 791 3.6E-61 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00930 6278b67464aff122775f2a3e509b5fe2 791 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 246 300 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c20150 4c40fe359927c6cb5e93880651d4b2ff 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 5.0E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c20150 4c40fe359927c6cb5e93880651d4b2ff 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 5.0E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c20150 4c40fe359927c6cb5e93880651d4b2ff 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 5.0E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c20150 4c40fe359927c6cb5e93880651d4b2ff 234 Gene3D G3DSA:3.40.50.720 1 233 9.0E-64 T 12-10-2018 TSC_c20150 4c40fe359927c6cb5e93880651d4b2ff 234 SUPERFAMILY SSF51735 2 234 6.09E-63 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c20150 4c40fe359927c6cb5e93880651d4b2ff 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 6.6E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c20150 4c40fe359927c6cb5e93880651d4b2ff 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 6.6E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c20150 4c40fe359927c6cb5e93880651d4b2ff 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 6.6E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c20150 4c40fe359927c6cb5e93880651d4b2ff 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 6.6E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c20150 4c40fe359927c6cb5e93880651d4b2ff 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 6.6E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c20150 4c40fe359927c6cb5e93880651d4b2ff 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 218 6.6E-30 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c20150 4c40fe359927c6cb5e93880651d4b2ff 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 233 4.7E-45 T 12-10-2018 TSC_c05560 7fa7629f8023c140d79d7a7502f2b87d 317 Pfam PF00753 Metallo-beta-lactamase superfamily 21 233 1.8E-25 T 12-10-2018 IPR001279 Metallo-beta-lactamase TSC_c05560 7fa7629f8023c140d79d7a7502f2b87d 317 SUPERFAMILY SSF56281 2 307 4.34E-62 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c05560 7fa7629f8023c140d79d7a7502f2b87d 317 Gene3D G3DSA:3.60.15.10 1 260 8.8E-84 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c05560 7fa7629f8023c140d79d7a7502f2b87d 317 SMART SM00849 21 233 3.1E-32 T 12-10-2018 IPR001279 Metallo-beta-lactamase TSC_c05560 7fa7629f8023c140d79d7a7502f2b87d 317 Gene3D G3DSA:1.10.10.10 262 317 9.8E-29 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c21940 ad76db5ad275d4c85b107e530ff47fc6 475 Pfam PF00128 Alpha amylase, catalytic domain 47 360 1.9E-69 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSC_c21940 ad76db5ad275d4c85b107e530ff47fc6 475 Gene3D G3DSA:3.20.20.80 1 390 1.4E-165 T 12-10-2018 TSC_c21940 ad76db5ad275d4c85b107e530ff47fc6 475 Gene3D G3DSA:2.60.40.1180 391 475 5.3E-49 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta TSC_c21940 ad76db5ad275d4c85b107e530ff47fc6 475 SMART SM00642 11 388 2.0E-108 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSC_c21940 ad76db5ad275d4c85b107e530ff47fc6 475 SUPERFAMILY SSF51011 399 472 2.09E-6 T 12-10-2018 TSC_c21940 ad76db5ad275d4c85b107e530ff47fc6 475 SUPERFAMILY SSF51445 2 395 3.88E-104 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TSC_c05770 15012cd70f90abea33ecbb10607e25a4 276 Gene3D G3DSA:3.40.50.300 13 255 5.8E-56 T 12-10-2018 TSC_c05770 15012cd70f90abea33ecbb10607e25a4 276 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c05770 15012cd70f90abea33ecbb10607e25a4 276 SMART SM00382 41 233 1.8E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c05770 15012cd70f90abea33ecbb10607e25a4 276 SUPERFAMILY SSF52540 15 253 1.6E-55 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c05770 15012cd70f90abea33ecbb10607e25a4 276 Pfam PF00005 ABC transporter 32 181 1.1E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c24480 425735728c0f59e7109ec6bb7db9223b 231 SUPERFAMILY SSF51261 97 204 8.37E-17 T 12-10-2018 IPR011055 Duplicated hybrid motif TSC_c24480 425735728c0f59e7109ec6bb7db9223b 231 Gene3D G3DSA:2.70.70.10 49 208 5.1E-16 T 12-10-2018 IPR011055 Duplicated hybrid motif TSC_c24480 425735728c0f59e7109ec6bb7db9223b 231 Pfam PF01551 Peptidase family M23 120 203 4.8E-11 T 12-10-2018 IPR016047 Peptidase M23 TSC_c10750 e376d956a73c0273539b0e8b19fe3e02 520 PIRSF PIRSF002741 17 518 7.8E-82 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSC_c10750 e376d956a73c0273539b0e8b19fe3e02 520 Gene3D G3DSA:3.40.190.10 200 507 5.5E-114 T 12-10-2018 TSC_c10750 e376d956a73c0273539b0e8b19fe3e02 520 Gene3D G3DSA:3.10.105.10 278 495 5.5E-114 T 12-10-2018 TSC_c10750 e376d956a73c0273539b0e8b19fe3e02 520 SUPERFAMILY SSF53850 21 518 4.73E-113 T 12-10-2018 TSC_c10750 e376d956a73c0273539b0e8b19fe3e02 520 Gene3D G3DSA:3.90.76.10 35 199 5.5E-114 T 12-10-2018 TSC_c10750 e376d956a73c0273539b0e8b19fe3e02 520 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 68 434 2.9E-81 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TSC_c14530 967205ac81ec83e6616b76d228ada3d3 265 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 173 255 1.4E-21 T 12-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSC_c14530 967205ac81ec83e6616b76d228ada3d3 265 Pfam PF01565 FAD binding domain 32 130 8.4E-10 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TSC_c14530 967205ac81ec83e6616b76d228ada3d3 265 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 8 256 1.7E-45 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSC_c14530 967205ac81ec83e6616b76d228ada3d3 265 Gene3D G3DSA:3.90.78.10 189 265 2.1E-34 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSC_c14530 967205ac81ec83e6616b76d228ada3d3 265 SUPERFAMILY SSF56176 8 181 8.0E-29 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSC_c14530 967205ac81ec83e6616b76d228ada3d3 265 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 265 63.184 T 12-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSC_c14530 967205ac81ec83e6616b76d228ada3d3 265 Gene3D G3DSA:3.30.43.10 1 67 2.1E-27 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TSC_c14530 967205ac81ec83e6616b76d228ada3d3 265 Gene3D G3DSA:3.30.465.10 68 188 4.0E-41 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSC_c14530 967205ac81ec83e6616b76d228ada3d3 265 SUPERFAMILY SSF56194 173 263 4.05E-26 T 12-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSC_c08730 318b1f7a0c000d4835bf1da0fb070d4f 652 Gene3D G3DSA:3.30.70.2750 135 203 5.2E-31 T 12-10-2018 TSC_c08730 318b1f7a0c000d4835bf1da0fb070d4f 652 Pfam PF01496 V-type ATPase 116kDa subunit family 215 432 4.2E-13 T 12-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c08730 318b1f7a0c000d4835bf1da0fb070d4f 652 Gene3D G3DSA:1.20.1460.20 47 134 3.0E-35 T 12-10-2018 TSC_c08730 318b1f7a0c000d4835bf1da0fb070d4f 652 Gene3D G3DSA:3.30.70.2170 227 303 6.0E-27 T 12-10-2018 TSC_c08730 318b1f7a0c000d4835bf1da0fb070d4f 652 Gene3D G3DSA:3.30.70.2170 2 46 5.2E-15 T 12-10-2018 TSC_c22290 783180717a4ffabc5e60fcdd2cbf28dd 180 SUPERFAMILY SSF56053 1 82 2.09E-24 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22290 783180717a4ffabc5e60fcdd2cbf28dd 180 Pfam PF00347 Ribosomal protein L6 91 164 3.5E-15 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22290 783180717a4ffabc5e60fcdd2cbf28dd 180 Pfam PF00347 Ribosomal protein L6 12 82 1.8E-19 T 12-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22290 783180717a4ffabc5e60fcdd2cbf28dd 180 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 175 1.1E-65 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TSC_c22290 783180717a4ffabc5e60fcdd2cbf28dd 180 PIRSF PIRSF002162 1 177 1.3E-41 T 12-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22290 783180717a4ffabc5e60fcdd2cbf28dd 180 Gene3D G3DSA:3.90.930.12 1 82 4.2E-31 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22290 783180717a4ffabc5e60fcdd2cbf28dd 180 Gene3D G3DSA:3.90.930.12 83 180 6.2E-35 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22290 783180717a4ffabc5e60fcdd2cbf28dd 180 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 34.631 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TSC_c22290 783180717a4ffabc5e60fcdd2cbf28dd 180 PRINTS PR00059 Ribosomal protein L6 signature 141 162 4.9E-26 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TSC_c22290 783180717a4ffabc5e60fcdd2cbf28dd 180 PRINTS PR00059 Ribosomal protein L6 signature 71 96 4.9E-26 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TSC_c22290 783180717a4ffabc5e60fcdd2cbf28dd 180 PRINTS PR00059 Ribosomal protein L6 signature 99 115 4.9E-26 T 12-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 TSC_c22290 783180717a4ffabc5e60fcdd2cbf28dd 180 SUPERFAMILY SSF56053 83 176 3.27E-31 T 12-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c23080 541889aa96aa6ef4d110fc2af8f2d5f8 280 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 1 279 14.116 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TSC_c23080 541889aa96aa6ef4d110fc2af8f2d5f8 280 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 3 272 1.4E-55 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TSC_c23080 541889aa96aa6ef4d110fc2af8f2d5f8 280 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 2 266 2.3E-39 T 12-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 TSC_c01840 2d7e7e65bfd44371ce7f0801ca333f53 263 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 29 263 40.101 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TSC_c01840 2d7e7e65bfd44371ce7f0801ca333f53 263 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 29 262 3.9E-76 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TSC_c01840 2d7e7e65bfd44371ce7f0801ca333f53 263 Pfam PF01255 Putative undecaprenyl diphosphate synthase 36 262 3.1E-80 T 12-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 TSC_c01840 2d7e7e65bfd44371ce7f0801ca333f53 263 SUPERFAMILY SSF64005 27 258 3.66E-82 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TSC_c01840 2d7e7e65bfd44371ce7f0801ca333f53 263 Gene3D G3DSA:3.40.1180.10 15 263 7.5E-97 T 12-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 TSC_c01840 2d7e7e65bfd44371ce7f0801ca333f53 263 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 208 225 - T 12-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 TSC_c05860 87529bb8a0f26fd0c307c64c456f5478 305 SUPERFAMILY SSF55048 125 190 5.62E-16 T 12-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding TSC_c05860 87529bb8a0f26fd0c307c64c456f5478 305 PIRSF PIRSF000446 1 303 6.1E-92 T 12-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 TSC_c05860 87529bb8a0f26fd0c307c64c456f5478 305 SUPERFAMILY SSF52151 1 302 2.01E-71 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TSC_c05860 87529bb8a0f26fd0c307c64c456f5478 305 Gene3D G3DSA:3.40.366.10 5 278 1.1E-110 T 12-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 TSC_c05860 87529bb8a0f26fd0c307c64c456f5478 305 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 1 284 3.2E-94 T 12-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 TSC_c05860 87529bb8a0f26fd0c307c64c456f5478 305 Gene3D G3DSA:3.30.70.250 122 190 1.1E-110 T 12-10-2018 TSC_c05860 87529bb8a0f26fd0c307c64c456f5478 305 Pfam PF00698 Acyl transferase domain 5 287 5.7E-45 T 12-10-2018 IPR014043 Acyl transferase TSC_c05860 87529bb8a0f26fd0c307c64c456f5478 305 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 295 6.6E-55 T 12-10-2018 IPR020801 Polyketide synthase, acyl transferase domain TSC_c06990 a028f9bd3a364ac557719f7e5e79a488 294 Gene3D G3DSA:3.40.50.620 2 173 4.0E-46 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c06990 a028f9bd3a364ac557719f7e5e79a488 294 SUPERFAMILY SSF82114 160 293 3.49E-43 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TSC_c06990 a028f9bd3a364ac557719f7e5e79a488 294 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 15 56 2.0E-7 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSC_c06990 a028f9bd3a364ac557719f7e5e79a488 294 SMART SM00904 170 293 6.1E-59 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 TSC_c06990 a028f9bd3a364ac557719f7e5e79a488 294 Pfam PF01687 Riboflavin kinase 171 292 1.0E-35 T 12-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 TSC_c06990 a028f9bd3a364ac557719f7e5e79a488 294 PIRSF PIRSF004491 1 293 2.9E-93 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 TSC_c06990 a028f9bd3a364ac557719f7e5e79a488 294 Gene3D G3DSA:2.40.30.30 175 293 1.8E-41 T 12-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 TSC_c06990 a028f9bd3a364ac557719f7e5e79a488 294 SUPERFAMILY SSF52374 14 170 3.38E-24 T 12-10-2018 TSC_c06990 a028f9bd3a364ac557719f7e5e79a488 294 Pfam PF06574 FAD synthetase 13 153 5.1E-35 T 12-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 TSC_c06990 a028f9bd3a364ac557719f7e5e79a488 294 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 16 292 4.4E-75 T 12-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 TSC_c11910 fa49d470c6ae7d93b2d745415ffb06ba 191 SUPERFAMILY SSF48498 75 186 1.01E-27 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSC_c11910 fa49d470c6ae7d93b2d745415ffb06ba 191 SUPERFAMILY SSF46689 3 77 7.18E-20 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSC_c11910 fa49d470c6ae7d93b2d745415ffb06ba 191 Gene3D G3DSA:1.10.357.10 47 190 1.4E-42 T 12-10-2018 TSC_c11910 fa49d470c6ae7d93b2d745415ffb06ba 191 ProSitePatterns PS01081 TetR-type HTH domain signature. 21 52 - T 12-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site TSC_c11910 fa49d470c6ae7d93b2d745415ffb06ba 191 Gene3D G3DSA:1.10.10.60 3 45 6.0E-24 T 12-10-2018 TSC_c11910 fa49d470c6ae7d93b2d745415ffb06ba 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 1.2E-19 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSC_c11910 fa49d470c6ae7d93b2d745415ffb06ba 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 9.4E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSC_c11910 fa49d470c6ae7d93b2d745415ffb06ba 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 9.4E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSC_c18610 09430d6259f613fd4f3ddd60fa5e914b 121 SUPERFAMILY SSF53474 4 93 1.17E-15 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c18610 09430d6259f613fd4f3ddd60fa5e914b 121 Gene3D G3DSA:3.40.50.12270 1 121 2.3E-47 T 12-10-2018 TSC_c03290 630efc7fd78e0f76d617a62a0be22439 73 SMART SM00357 3 68 9.0E-30 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 TSC_c03290 630efc7fd78e0f76d617a62a0be22439 73 Pfam PF00313 'Cold-shock' DNA-binding domain 3 67 7.9E-27 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSC_c03290 630efc7fd78e0f76d617a62a0be22439 73 PIRSF PIRSF002599 1 73 1.7E-24 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 TSC_c03290 630efc7fd78e0f76d617a62a0be22439 73 PRINTS PR00050 Cold shock protein signature 24 33 2.0E-16 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSC_c03290 630efc7fd78e0f76d617a62a0be22439 73 PRINTS PR00050 Cold shock protein signature 4 19 2.0E-16 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSC_c03290 630efc7fd78e0f76d617a62a0be22439 73 PRINTS PR00050 Cold shock protein signature 39 57 2.0E-16 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSC_c03290 630efc7fd78e0f76d617a62a0be22439 73 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 12-10-2018 IPR019844 Cold-shock conserved site TSC_c03290 630efc7fd78e0f76d617a62a0be22439 73 SUPERFAMILY SSF50249 1 69 4.5E-23 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c03290 630efc7fd78e0f76d617a62a0be22439 73 Gene3D G3DSA:2.40.50.140 1 73 6.3E-33 T 12-10-2018 TSC_c11420 71324c582d467ceb9880bb1b2b022b6c 236 SUPERFAMILY SSF102588 1 235 2.09E-47 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TSC_c11420 71324c582d467ceb9880bb1b2b022b6c 236 Gene3D G3DSA:3.40.50.10320 1 236 9.4E-74 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TSC_c11420 71324c582d467ceb9880bb1b2b022b6c 236 Pfam PF02585 GlcNAc-PI de-N-acetylase 5 133 7.2E-21 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TSC_c01350 5fd3dc50bc1578243142478f4778eb1a 205 Gene3D G3DSA:3.30.420.10 6 204 2.2E-65 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSC_c01350 5fd3dc50bc1578243142478f4778eb1a 205 SUPERFAMILY SSF53098 17 197 1.44E-59 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c01350 5fd3dc50bc1578243142478f4778eb1a 205 Hamap MF_00052_B Ribonuclease HII [rnhB]. 18 194 32.383 T 12-10-2018 IPR022898 Ribonuclease HII GO:0004523 TSC_c01350 5fd3dc50bc1578243142478f4778eb1a 205 Pfam PF01351 Ribonuclease HII 20 193 5.6E-30 T 12-10-2018 IPR024567 Ribonuclease HII/HIII domain TSC_c13020 323b6848af0f048730d12565a8ca7dcd 409 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 153 165 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSC_c13020 323b6848af0f048730d12565a8ca7dcd 409 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 36 144 7.3E-31 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSC_c13020 323b6848af0f048730d12565a8ca7dcd 409 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 151 246 1.7E-25 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSC_c13020 323b6848af0f048730d12565a8ca7dcd 409 Gene3D G3DSA:1.10.540.10 22 149 6.6E-41 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSC_c13020 323b6848af0f048730d12565a8ca7dcd 409 PIRSF PIRSF016578 27 113 1.1E-4 T 12-10-2018 TSC_c13020 323b6848af0f048730d12565a8ca7dcd 409 PIRSF PIRSF016578 160 409 6.0E-16 T 12-10-2018 TSC_c13020 323b6848af0f048730d12565a8ca7dcd 409 Gene3D G3DSA:2.40.110.10 150 263 3.6E-42 T 12-10-2018 TSC_c13020 323b6848af0f048730d12565a8ca7dcd 409 SUPERFAMILY SSF56645 27 269 1.13E-81 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSC_c13020 323b6848af0f048730d12565a8ca7dcd 409 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 258 407 1.1E-54 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSC_c13020 323b6848af0f048730d12565a8ca7dcd 409 Gene3D G3DSA:1.20.140.10 264 409 1.1E-60 T 12-10-2018 TSC_c13020 323b6848af0f048730d12565a8ca7dcd 409 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 365 384 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSC_c13020 323b6848af0f048730d12565a8ca7dcd 409 SUPERFAMILY SSF47203 256 408 6.88E-63 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSC_c01600 9735a9ba22cf3c6e52eaceb01ec9b6e2 127 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 6 123 20.247 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TSC_c01600 9735a9ba22cf3c6e52eaceb01ec9b6e2 127 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 7 118 3.1E-25 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TSC_c01600 9735a9ba22cf3c6e52eaceb01ec9b6e2 127 TIGRFAM TIGR00494 crcB: protein CrcB 7 120 1.4E-28 T 12-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 TSC_c05690 a8ca51d3a6207753867acc3c95e14184 85 Pfam PF01809 Haemolytic domain 4 68 2.4E-29 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TSC_c05690 a8ca51d3a6207753867acc3c95e14184 85 SMART SM01234 1 68 8.8E-44 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TSC_c05690 a8ca51d3a6207753867acc3c95e14184 85 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 2.0E-23 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TSC_c05690 a8ca51d3a6207753867acc3c95e14184 85 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 70 5.4E-30 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TSC_c05690 a8ca51d3a6207753867acc3c95e14184 85 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 24.581 T 12-10-2018 IPR002696 Putative membrane protein insertion efficiency factor TSC_c17930 4af7a54e9b38199a5341ee4d488e001a 405 Gene3D G3DSA:3.40.50.1100 61 394 2.1E-183 T 12-10-2018 TSC_c17930 4af7a54e9b38199a5341ee4d488e001a 405 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 88 102 - T 12-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TSC_c17930 4af7a54e9b38199a5341ee4d488e001a 405 SUPERFAMILY SSF53686 10 399 1.57E-148 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSC_c17930 4af7a54e9b38199a5341ee4d488e001a 405 Gene3D G3DSA:3.40.50.1100 17 213 2.1E-183 T 12-10-2018 TSC_c17930 4af7a54e9b38199a5341ee4d488e001a 405 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 59 388 6.9E-51 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSC_c17930 4af7a54e9b38199a5341ee4d488e001a 405 PIRSF PIRSF001413 2 405 8.0E-161 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TSC_c17930 4af7a54e9b38199a5341ee4d488e001a 405 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 9 401 53.401 T 12-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TSC_c17930 4af7a54e9b38199a5341ee4d488e001a 405 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 14 399 7.2E-185 T 12-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TSC_c13030 79139e7ff9d598a498e6d88d00302f6e 247 SMART SM00893 21 208 1.2E-42 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TSC_c13030 79139e7ff9d598a498e6d88d00302f6e 247 Gene3D G3DSA:3.40.50.620 1 246 5.3E-69 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c13030 79139e7ff9d598a498e6d88d00302f6e 247 PIRSF PIRSF000090 1 247 2.8E-66 T 12-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 TSC_c13030 79139e7ff9d598a498e6d88d00302f6e 247 SUPERFAMILY SSF52402 1 230 2.58E-61 T 12-10-2018 TSC_c13030 79139e7ff9d598a498e6d88d00302f6e 247 Pfam PF01012 Electron transfer flavoprotein domain 30 200 1.8E-37 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TSC_c13380 b8026444b9ef1bc230810daf2d2959cb 122 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 2 118 4.9E-41 T 12-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TSC_c13380 b8026444b9ef1bc230810daf2d2959cb 122 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 8 121 2.0E-57 T 12-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TSC_c13380 b8026444b9ef1bc230810daf2d2959cb 122 PIRSF PIRSF005965 1 122 5.9E-48 T 12-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TSC_c13380 b8026444b9ef1bc230810daf2d2959cb 122 Gene3D G3DSA:3.30.1330.40 1 122 2.2E-52 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSC_c13380 b8026444b9ef1bc230810daf2d2959cb 122 Pfam PF07736 Chorismate mutase type I 2 118 8.3E-45 T 12-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 TSC_c13380 b8026444b9ef1bc230810daf2d2959cb 122 SUPERFAMILY SSF55298 1 118 3.92E-46 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSC_c04620 c2e02364676aba9533e75c6a609aa647 276 Pfam PF00892 EamA-like transporter family 7 130 1.3E-8 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSC_c04620 c2e02364676aba9533e75c6a609aa647 276 Pfam PF00892 EamA-like transporter family 141 268 4.7E-19 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSC_c04620 c2e02364676aba9533e75c6a609aa647 276 SUPERFAMILY SSF103481 40 134 7.72E-5 T 12-10-2018 TSC_c04620 c2e02364676aba9533e75c6a609aa647 276 SUPERFAMILY SSF103481 179 274 7.85E-15 T 12-10-2018 TSC_c02280 fcd1f7939b2d10f31af261ae5dab33ec 224 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 79 94 - T 12-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TSC_c02280 fcd1f7939b2d10f31af261ae5dab33ec 224 Hamap MF_00013 Octanoyltransferase [lipB]. 6 212 33.925 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TSC_c02280 fcd1f7939b2d10f31af261ae5dab33ec 224 SUPERFAMILY SSF55681 5 212 2.65E-62 T 12-10-2018 TSC_c02280 fcd1f7939b2d10f31af261ae5dab33ec 224 Gene3D G3DSA:3.30.930.10 5 210 6.1E-79 T 12-10-2018 TSC_c02280 fcd1f7939b2d10f31af261ae5dab33ec 224 PIRSF PIRSF016262 4 223 5.1E-57 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TSC_c02280 fcd1f7939b2d10f31af261ae5dab33ec 224 Pfam PF03099 Biotin/lipoate A/B protein ligase family 67 164 9.4E-6 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TSC_c02280 fcd1f7939b2d10f31af261ae5dab33ec 224 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 39 210 1.5E-44 T 12-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TSC_c02280 fcd1f7939b2d10f31af261ae5dab33ec 224 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 83 127 7.0E-17 T 12-10-2018 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 Pfam PF09281 Taq polymerase, exonuclease 293 418 4.0E-45 T 12-10-2018 IPR015361 Taq polymerase, thermostable, exonuclease region GO:0001882|GO:0003887|GO:0006260|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 Gene3D G3DSA:3.30.70.370 565 825 1.3E-119 T 12-10-2018 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 Pfam PF00476 DNA polymerase family A 453 826 4.5E-149 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 657 682 1.7E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 694 705 1.7E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 716 727 1.7E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 748 764 1.7E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 633 646 1.7E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 558 580 1.7E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 603 626 1.7E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 581 596 1.7E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 PRINTS PR00868 DNA-polymerase family A (pol I) signature 776 789 1.7E-83 T 12-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 SMART SM00279 173 208 3.3E-17 T 12-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 SMART SM00475 9 262 7.1E-146 T 12-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 Gene3D G3DSA:3.30.420.10 291 444 3.1E-66 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 Gene3D G3DSA:1.10.150.20 612 755 1.3E-119 T 12-10-2018 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 Gene3D G3DSA:1.10.150.20 174 247 3.4E-103 T 12-10-2018 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 11 170 3.7E-48 T 12-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 ProSitePatterns PS00447 DNA polymerase family A signature. 657 676 - T 12-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 SUPERFAMILY SSF47807 171 284 5.68E-34 T 12-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 SUPERFAMILY SSF56672 422 829 6.12E-156 T 12-10-2018 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 SUPERFAMILY SSF53098 293 419 2.28E-30 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 SUPERFAMILY SSF88723 4 170 1.1E-52 T 12-10-2018 IPR029060 PIN-like domain superfamily TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 SMART SM00482 589 793 1.5E-121 T 12-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 TIGRFAM TIGR00593 pola: DNA polymerase I 386 829 6.2E-203 T 12-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 172 258 4.8E-29 T 12-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 Gene3D G3DSA:3.40.50.1010 11 276 3.4E-103 T 12-10-2018 TSC_c09390 e42e99d99a1ecd682332388c7e303ae0 830 Gene3D G3DSA:1.20.1060.10 445 561 3.9E-45 T 12-10-2018 TSC_c22680 14f0747a9b269c1286571cc45f68b08e 220 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 74 1.4E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSC_c22680 14f0747a9b269c1286571cc45f68b08e 220 SMART SM00345 16 74 1.2E-21 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSC_c22680 14f0747a9b269c1286571cc45f68b08e 220 SUPERFAMILY SSF46785 9 78 2.5E-21 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c22680 14f0747a9b269c1286571cc45f68b08e 220 SUPERFAMILY SSF48008 79 213 2.09E-29 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSC_c22680 14f0747a9b269c1286571cc45f68b08e 220 SMART SM00895 84 206 1.5E-25 T 12-10-2018 IPR011711 GntR, C-terminal TSC_c22680 14f0747a9b269c1286571cc45f68b08e 220 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 6.9E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSC_c22680 14f0747a9b269c1286571cc45f68b08e 220 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 6.9E-7 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSC_c22680 14f0747a9b269c1286571cc45f68b08e 220 Pfam PF07729 FCD domain 84 204 3.9E-29 T 12-10-2018 IPR011711 GntR, C-terminal TSC_c22680 14f0747a9b269c1286571cc45f68b08e 220 Gene3D G3DSA:1.10.10.10 10 75 1.4E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c22680 14f0747a9b269c1286571cc45f68b08e 220 Gene3D G3DSA:1.20.120.530 79 218 1.8E-34 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSC_c18080 db77d3b3c144d1eb7ef4ff5cc838e693 867 SMART SM00382 536 706 3.6E-5 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c18080 db77d3b3c144d1eb7ef4ff5cc838e693 867 Gene3D G3DSA:1.10.10.10 791 856 1.8E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c18080 db77d3b3c144d1eb7ef4ff5cc838e693 867 Gene3D G3DSA:3.40.50.300 498 776 3.6E-98 T 12-10-2018 TSC_c18080 db77d3b3c144d1eb7ef4ff5cc838e693 867 Pfam PF01580 FtsK/SpoIIIE family 640 691 1.3E-14 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 TSC_c18080 db77d3b3c144d1eb7ef4ff5cc838e693 867 Pfam PF01580 FtsK/SpoIIIE family 503 637 4.0E-40 T 12-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 TSC_c18080 db77d3b3c144d1eb7ef4ff5cc838e693 867 Pfam PF09397 Ftsk gamma domain 798 857 1.1E-24 T 12-10-2018 IPR018541 FtsK gamma domain TSC_c18080 db77d3b3c144d1eb7ef4ff5cc838e693 867 SUPERFAMILY SSF52540 475 758 1.31E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c18080 db77d3b3c144d1eb7ef4ff5cc838e693 867 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 38 128 2.7E-7 T 12-10-2018 IPR025199 DNA translocase FtsK, 4TM region TSC_c18080 db77d3b3c144d1eb7ef4ff5cc838e693 867 SUPERFAMILY SSF46785 796 861 4.08E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c18080 db77d3b3c144d1eb7ef4ff5cc838e693 867 SMART SM00843 795 860 3.7E-31 T 12-10-2018 IPR018541 FtsK gamma domain TSC_c18080 db77d3b3c144d1eb7ef4ff5cc838e693 867 Gene3D G3DSA:3.30.980.40 392 497 2.9E-32 T 12-10-2018 TSC_c12830 ab6ea9cd7abab575148292b11387a923 346 Pfam PF08402 TOBE domain 274 344 5.0E-9 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSC_c12830 ab6ea9cd7abab575148292b11387a923 346 Gene3D G3DSA:3.40.50.300 4 245 4.8E-79 T 12-10-2018 TSC_c12830 ab6ea9cd7abab575148292b11387a923 346 Pfam PF00005 ABC transporter 26 168 3.2E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c12830 ab6ea9cd7abab575148292b11387a923 346 SUPERFAMILY SSF52540 12 249 1.73E-87 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c12830 ab6ea9cd7abab575148292b11387a923 346 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c12830 ab6ea9cd7abab575148292b11387a923 346 SMART SM00382 35 218 1.9E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c12830 ab6ea9cd7abab575148292b11387a923 346 SUPERFAMILY SSF50331 245 345 4.62E-12 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSC_c11120 25ed841d222c94db65091e07aa1788ad 378 SUPERFAMILY SSF88713 178 372 2.63E-65 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSC_c11120 25ed841d222c94db65091e07aa1788ad 378 Pfam PF01522 Polysaccharide deacetylase 186 308 4.7E-37 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 TSC_c11120 25ed841d222c94db65091e07aa1788ad 378 Gene3D G3DSA:3.20.20.370 151 377 5.8E-63 T 12-10-2018 TSC_c23260 47ec7fc9c1e1e6921520d316232ca12e 310 SMART SM01400 5 121 3.2E-66 T 12-10-2018 TSC_c23260 47ec7fc9c1e1e6921520d316232ca12e 310 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 6 121 5.6E-43 T 12-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TSC_c23260 47ec7fc9c1e1e6921520d316232ca12e 310 SUPERFAMILY SSF53271 70 301 1.83E-56 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TSC_c23260 47ec7fc9c1e1e6921520d316232ca12e 310 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 5 310 43.371 T 12-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 TSC_c23260 47ec7fc9c1e1e6921520d316232ca12e 310 Pfam PF14572 Phosphoribosyl synthetase-associated domain 207 309 2.6E-22 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TSC_c23260 47ec7fc9c1e1e6921520d316232ca12e 310 Gene3D G3DSA:3.40.50.2020 8 300 3.1E-113 T 12-10-2018 TSC_c23260 47ec7fc9c1e1e6921520d316232ca12e 310 Gene3D G3DSA:3.40.50.2020 148 286 3.1E-113 T 12-10-2018 TSC_c23260 47ec7fc9c1e1e6921520d316232ca12e 310 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 6 310 5.6E-115 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TSC_c04580 09742ed5e3dc3225bbe6b6ea8c1d66d6 341 Gene3D G3DSA:3.40.1010.20 15 305 1.6E-95 T 12-10-2018 TSC_c04580 09742ed5e3dc3225bbe6b6ea8c1d66d6 341 Gene3D G3DSA:3.40.50.11270 20 113 1.6E-95 T 12-10-2018 TSC_c04580 09742ed5e3dc3225bbe6b6ea8c1d66d6 341 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 11 308 5.6E-90 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TSC_c04580 09742ed5e3dc3225bbe6b6ea8c1d66d6 341 Pfam PF02401 LytB protein 12 306 1.1E-79 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TSC_c04580 09742ed5e3dc3225bbe6b6ea8c1d66d6 341 Gene3D G3DSA:3.40.1010.20 114 220 1.6E-95 T 12-10-2018 TSC_c04580 09742ed5e3dc3225bbe6b6ea8c1d66d6 341 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 9 310 33.835 T 12-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 TSC_c10670 e478f484ddc1554646b9570edf28cf53 182 Gene3D G3DSA:1.20.1290.10 62 182 2.6E-39 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSC_c10670 e478f484ddc1554646b9570edf28cf53 182 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 4 177 4.9E-53 T 12-10-2018 IPR010195 Uncharacterised peroxidase-related TSC_c10670 e478f484ddc1554646b9570edf28cf53 182 SUPERFAMILY SSF69118 3 180 7.2E-49 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSC_c10670 e478f484ddc1554646b9570edf28cf53 182 Gene3D G3DSA:1.20.5.810 11 60 2.3E-15 T 12-10-2018 TSC_c10670 e478f484ddc1554646b9570edf28cf53 182 Pfam PF02627 Carboxymuconolactone decarboxylase family 47 128 3.2E-9 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSC_c10670 e478f484ddc1554646b9570edf28cf53 182 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 60 106 2.5E-9 T 12-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSC_c13410 02f0cad527e6df573b34e492f79294b8 170 Pfam PF03602 Conserved hypothetical protein 95 1 153 3.1E-31 T 12-10-2018 TSC_c13410 02f0cad527e6df573b34e492f79294b8 170 PIRSF PIRSF004553 1 170 9.7E-34 T 12-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 TSC_c13410 02f0cad527e6df573b34e492f79294b8 170 SUPERFAMILY SSF53335 1 167 9.98E-39 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c13410 02f0cad527e6df573b34e492f79294b8 170 Gene3D G3DSA:3.40.50.150 1 170 5.5E-48 T 12-10-2018 TSC_c02680 2b6c9769bb1b4ee080aa5206ee081ee8 910 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 19 48 3.0E-9 T 12-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TSC_c02680 2b6c9769bb1b4ee080aa5206ee081ee8 910 Gene3D G3DSA:1.10.287.1150 76 148 8.9E-12 T 12-10-2018 TSC_c02680 2b6c9769bb1b4ee080aa5206ee081ee8 910 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 772 909 7.8E-39 T 12-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TSC_c02680 2b6c9769bb1b4ee080aa5206ee081ee8 910 SMART SM00861 575 768 4.1E-56 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSC_c02680 2b6c9769bb1b4ee080aa5206ee081ee8 910 PIRSF PIRSF000157 9 910 0.0 T 12-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TSC_c02680 2b6c9769bb1b4ee080aa5206ee081ee8 910 Pfam PF00676 Dehydrogenase E1 component 189 504 3.0E-44 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TSC_c02680 2b6c9769bb1b4ee080aa5206ee081ee8 910 SUPERFAMILY SSF52518 557 775 6.67E-50 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c02680 2b6c9769bb1b4ee080aa5206ee081ee8 910 Pfam PF02779 Transketolase, pyrimidine binding domain 574 769 1.1E-62 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSC_c02680 2b6c9769bb1b4ee080aa5206ee081ee8 910 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 19 908 2.7E-301 T 12-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 TSC_c02680 2b6c9769bb1b4ee080aa5206ee081ee8 910 Gene3D G3DSA:3.40.50.11610 705 906 4.7E-159 T 12-10-2018 TSC_c02680 2b6c9769bb1b4ee080aa5206ee081ee8 910 Gene3D G3DSA:3.40.50.970 149 504 1.1E-129 T 12-10-2018 TSC_c02680 2b6c9769bb1b4ee080aa5206ee081ee8 910 SUPERFAMILY SSF52518 137 517 3.07E-71 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c02680 2b6c9769bb1b4ee080aa5206ee081ee8 910 Gene3D G3DSA:3.40.50.12470 538 784 4.7E-159 T 12-10-2018 TSC_c22220 5fd0ea04310389a7c88b40c5cae29344 255 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 166 184 - T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSC_c22220 5fd0ea04310389a7c88b40c5cae29344 255 Gene3D G3DSA:3.90.230.10 1 251 1.2E-97 T 12-10-2018 TSC_c22220 5fd0ea04310389a7c88b40c5cae29344 255 SUPERFAMILY SSF55920 4 248 9.16E-83 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like TSC_c22220 5fd0ea04310389a7c88b40c5cae29344 255 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 3 247 6.8E-92 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSC_c22220 5fd0ea04310389a7c88b40c5cae29344 255 Hamap MF_01974 Methionine aminopeptidase [map]. 3 249 39.008 T 12-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSC_c22220 5fd0ea04310389a7c88b40c5cae29344 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 68 81 1.6E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSC_c22220 5fd0ea04310389a7c88b40c5cae29344 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 191 203 1.6E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSC_c22220 5fd0ea04310389a7c88b40c5cae29344 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 160 172 1.6E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSC_c22220 5fd0ea04310389a7c88b40c5cae29344 255 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 1.6E-20 T 12-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 TSC_c22220 5fd0ea04310389a7c88b40c5cae29344 255 Pfam PF00557 Metallopeptidase family M24 12 240 1.1E-52 T 12-10-2018 IPR000994 Peptidase M24 TSC_c16260 dd22e0489d550d2d20b5e844546ed85f 231 SUPERFAMILY SSF46785 177 223 6.76E-11 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c16260 dd22e0489d550d2d20b5e844546ed85f 231 Gene3D G3DSA:1.10.10.10 172 230 7.5E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c16260 dd22e0489d550d2d20b5e844546ed85f 231 Pfam PF12840 Helix-turn-helix domain 179 225 1.5E-9 T 12-10-2018 TSC_c03890 672e3dac9c26debeca1119920073ab8c 100 Pfam PF00355 Rieske [2Fe-2S] domain 2 88 3.7E-16 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TSC_c03890 672e3dac9c26debeca1119920073ab8c 100 SUPERFAMILY SSF50022 1 99 7.46E-27 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSC_c03890 672e3dac9c26debeca1119920073ab8c 100 Gene3D G3DSA:2.102.10.10 1 100 5.1E-28 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSC_c19720 e1ac3e54e1e8b3b555526aa453a4da87 583 Gene3D G3DSA:3.40.190.10 52 560 1.2E-99 T 12-10-2018 TSC_c19720 e1ac3e54e1e8b3b555526aa453a4da87 583 SUPERFAMILY SSF53850 37 569 1.52E-106 T 12-10-2018 TSC_c19720 e1ac3e54e1e8b3b555526aa453a4da87 583 PIRSF PIRSF002741 1 572 1.7E-73 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSC_c19720 e1ac3e54e1e8b3b555526aa453a4da87 583 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 85 478 1.9E-77 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TSC_c19720 e1ac3e54e1e8b3b555526aa453a4da87 583 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 90 112 - T 12-10-2018 IPR023765 Solute-binding protein family 5, conserved site TSC_c19720 e1ac3e54e1e8b3b555526aa453a4da87 583 Gene3D G3DSA:3.90.76.10 72 193 1.2E-99 T 12-10-2018 TSC_c19720 e1ac3e54e1e8b3b555526aa453a4da87 583 Gene3D G3DSA:3.10.105.10 309 547 1.2E-99 T 12-10-2018 TSC_c20910 e1db23af42279cf382c6d70ace0c1070 326 Pfam PF13432 Tetratricopeptide repeat 141 190 3.7E-5 T 12-10-2018 TSC_c20910 e1db23af42279cf382c6d70ace0c1070 326 Pfam PF13432 Tetratricopeptide repeat 195 230 2.3E-4 T 12-10-2018 TSC_c20910 e1db23af42279cf382c6d70ace0c1070 326 SUPERFAMILY SSF48452 137 237 5.69E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c20910 e1db23af42279cf382c6d70ace0c1070 326 SMART SM00028 171 204 140.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c20910 e1db23af42279cf382c6d70ace0c1070 326 SMART SM00028 205 238 0.098 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c20910 e1db23af42279cf382c6d70ace0c1070 326 SMART SM00028 137 170 39.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c20910 e1db23af42279cf382c6d70ace0c1070 326 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 257 323 6.9E-13 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c20910 e1db23af42279cf382c6d70ace0c1070 326 SUPERFAMILY SSF46626 210 326 1.09E-19 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c20910 e1db23af42279cf382c6d70ace0c1070 326 Gene3D G3DSA:1.10.760.10 258 326 6.4E-16 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c20910 e1db23af42279cf382c6d70ace0c1070 326 Gene3D G3DSA:1.25.40.10 139 257 1.1E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c08980 b01926db42308c5722a142d430d040e9 384 ProSitePatterns PS00737 Thiolases signature 2. 330 346 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 TSC_c08980 b01926db42308c5722a142d430d040e9 384 Gene3D G3DSA:3.40.47.10 6 267 8.2E-143 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c08980 b01926db42308c5722a142d430d040e9 384 SUPERFAMILY SSF53901 262 383 1.18E-39 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c08980 b01926db42308c5722a142d430d040e9 384 Pfam PF00108 Thiolase, N-terminal domain 5 251 1.4E-66 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TSC_c08980 b01926db42308c5722a142d430d040e9 384 PIRSF PIRSF000429 1 384 7.8E-121 T 12-10-2018 IPR002155 Thiolase GO:0016747 TSC_c08980 b01926db42308c5722a142d430d040e9 384 SUPERFAMILY SSF53901 5 261 2.25E-76 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c08980 b01926db42308c5722a142d430d040e9 384 Pfam PF02803 Thiolase, C-terminal domain 262 383 1.1E-37 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TSC_c08980 b01926db42308c5722a142d430d040e9 384 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 382 7.7E-129 T 12-10-2018 IPR002155 Thiolase GO:0016747 TSC_c08980 b01926db42308c5722a142d430d040e9 384 Gene3D G3DSA:3.40.47.10 127 381 8.2E-143 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c12840 6c53a9c6ef0ae6c8f938984a3c433639 449 Gene3D G3DSA:3.90.1150.10 20 433 1.5E-126 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c12840 6c53a9c6ef0ae6c8f938984a3c433639 449 Gene3D G3DSA:3.40.640.10 87 340 1.5E-126 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c12840 6c53a9c6ef0ae6c8f938984a3c433639 449 Pfam PF00202 Aminotransferase class-III 48 426 1.6E-40 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c12840 6c53a9c6ef0ae6c8f938984a3c433639 449 SUPERFAMILY SSF53383 21 443 6.05E-84 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c02370 6dedb6cdaad3fd817713b801f42d534e 81 Gene3D G3DSA:3.30.920.30 8 65 6.8E-11 T 12-10-2018 IPR038570 HicA superfamily TSC_c02370 6dedb6cdaad3fd817713b801f42d534e 81 SUPERFAMILY SSF54786 8 65 5.1E-11 T 12-10-2018 TSC_c02370 6dedb6cdaad3fd817713b801f42d534e 81 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 10 63 6.5E-15 T 12-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 TSC_c20720 1e988070c3065078d52c59d09e327cb9 184 Pfam PF01202 Shikimate kinase 19 175 6.3E-46 T 12-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TSC_c20720 1e988070c3065078d52c59d09e327cb9 184 ProSitePatterns PS01128 Shikimate kinase signature. 66 91 - T 12-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TSC_c20720 1e988070c3065078d52c59d09e327cb9 184 Gene3D G3DSA:3.40.50.300 12 182 6.0E-55 T 12-10-2018 TSC_c20720 1e988070c3065078d52c59d09e327cb9 184 Hamap MF_00109 Shikimate kinase [aroK]. 10 176 28.882 T 12-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 TSC_c20720 1e988070c3065078d52c59d09e327cb9 184 PRINTS PR01100 Shikimate kinase family signature 83 92 8.0E-17 T 12-10-2018 TSC_c20720 1e988070c3065078d52c59d09e327cb9 184 PRINTS PR01100 Shikimate kinase family signature 104 121 8.0E-17 T 12-10-2018 TSC_c20720 1e988070c3065078d52c59d09e327cb9 184 PRINTS PR01100 Shikimate kinase family signature 13 28 8.0E-17 T 12-10-2018 TSC_c20720 1e988070c3065078d52c59d09e327cb9 184 PRINTS PR01100 Shikimate kinase family signature 37 50 8.0E-17 T 12-10-2018 TSC_c20720 1e988070c3065078d52c59d09e327cb9 184 PRINTS PR01100 Shikimate kinase family signature 65 73 8.0E-17 T 12-10-2018 TSC_c20720 1e988070c3065078d52c59d09e327cb9 184 SUPERFAMILY SSF52540 6 177 3.24E-27 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c00910 4d4903001b3f0ad1b1639a5e87240cc8 607 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 325 606 19.807 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 TSC_c00910 4d4903001b3f0ad1b1639a5e87240cc8 607 Pfam PF01040 UbiA prenyltransferase family 341 587 8.6E-64 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TSC_c00910 4d4903001b3f0ad1b1639a5e87240cc8 607 Gene3D G3DSA:1.10.357.140 336 490 9.9E-21 T 12-10-2018 TSC_c00910 4d4903001b3f0ad1b1639a5e87240cc8 607 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 327 604 6.0E-99 T 12-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 TSC_c00910 4d4903001b3f0ad1b1639a5e87240cc8 607 Pfam PF02628 Cytochrome oxidase assembly protein 8 291 3.7E-31 T 12-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 TSC_c09570 33f3ca89fb9427387f1ee60fcb744c61 482 Gene3D G3DSA:1.10.275.10 30 218 8.3E-86 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal TSC_c09570 33f3ca89fb9427387f1ee60fcb744c61 482 Gene3D G3DSA:1.20.200.10 108 347 8.3E-86 T 12-10-2018 TSC_c09570 33f3ca89fb9427387f1ee60fcb744c61 482 ProSitePatterns PS00163 Fumarate lyases signature. 262 271 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TSC_c09570 33f3ca89fb9427387f1ee60fcb744c61 482 PRINTS PR00149 Fumarate lyase superfamily signature 136 154 1.2E-16 T 12-10-2018 IPR000362 Fumarate lyase family TSC_c09570 33f3ca89fb9427387f1ee60fcb744c61 482 PRINTS PR00149 Fumarate lyase superfamily signature 91 109 1.2E-16 T 12-10-2018 IPR000362 Fumarate lyase family TSC_c09570 33f3ca89fb9427387f1ee60fcb744c61 482 PRINTS PR00149 Fumarate lyase superfamily signature 220 247 1.2E-16 T 12-10-2018 IPR000362 Fumarate lyase family TSC_c09570 33f3ca89fb9427387f1ee60fcb744c61 482 PRINTS PR00149 Fumarate lyase superfamily signature 262 278 1.2E-16 T 12-10-2018 IPR000362 Fumarate lyase family TSC_c09570 33f3ca89fb9427387f1ee60fcb744c61 482 PRINTS PR00145 Argininosuccinate lyase family signature 131 151 1.2E-23 T 12-10-2018 TSC_c09570 33f3ca89fb9427387f1ee60fcb744c61 482 PRINTS PR00145 Argininosuccinate lyase family signature 220 244 1.2E-23 T 12-10-2018 TSC_c09570 33f3ca89fb9427387f1ee60fcb744c61 482 PRINTS PR00145 Argininosuccinate lyase family signature 182 198 1.2E-23 T 12-10-2018 TSC_c09570 33f3ca89fb9427387f1ee60fcb744c61 482 PRINTS PR00145 Argininosuccinate lyase family signature 262 278 1.2E-23 T 12-10-2018 TSC_c09570 33f3ca89fb9427387f1ee60fcb744c61 482 PRINTS PR00145 Argininosuccinate lyase family signature 90 112 1.2E-23 T 12-10-2018 TSC_c09570 33f3ca89fb9427387f1ee60fcb744c61 482 SUPERFAMILY SSF48557 19 430 1.34E-74 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 TSC_c09570 33f3ca89fb9427387f1ee60fcb744c61 482 Gene3D G3DSA:1.10.40.30 348 378 8.3E-86 T 12-10-2018 TSC_c09570 33f3ca89fb9427387f1ee60fcb744c61 482 Pfam PF00206 Lyase 85 287 9.9E-38 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal TSC_c10310 3cc9f28834242d1118b22dfe131b70c3 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 6 276 2.3E-58 T 12-10-2018 IPR003797 DegV TSC_c10310 3cc9f28834242d1118b22dfe131b70c3 280 Gene3D G3DSA:3.30.1180.10 155 278 2.7E-25 T 12-10-2018 TSC_c10310 3cc9f28834242d1118b22dfe131b70c3 280 Gene3D G3DSA:3.40.50.10170 5 151 3.7E-33 T 12-10-2018 TSC_c10310 3cc9f28834242d1118b22dfe131b70c3 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 8 275 5.8E-66 T 12-10-2018 IPR003797 DegV TSC_c10310 3cc9f28834242d1118b22dfe131b70c3 280 SUPERFAMILY SSF82549 6 276 7.06E-64 T 12-10-2018 TSC_c12440 b0709f2d9cb1c9572f61c140de692ba5 114 TIGRFAM TIGR01873 cas_CT1978: CRISPR-associated endoribonuclease Cas2, subtype I-E/ECOLI 1 86 6.8E-19 T 12-10-2018 IPR010152 CRISPR-associated protein Cas2 subtype TSC_c12440 b0709f2d9cb1c9572f61c140de692ba5 114 Gene3D G3DSA:3.30.70.240 1 75 3.2E-31 T 12-10-2018 TSC_c12440 b0709f2d9cb1c9572f61c140de692ba5 114 Pfam PF09707 CRISPR-associated protein (Cas_Cas2CT1978) 1 86 6.7E-34 T 12-10-2018 IPR010152 CRISPR-associated protein Cas2 subtype TSC_c17520 d0104b9a8054b4edeaae112a1456fe24 264 SUPERFAMILY SSF46626 111 218 9.89E-13 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c17520 d0104b9a8054b4edeaae112a1456fe24 264 Gene3D G3DSA:1.10.760.10 130 222 5.1E-5 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c17520 d0104b9a8054b4edeaae112a1456fe24 264 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 19 102 2.0E-11 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c17520 d0104b9a8054b4edeaae112a1456fe24 264 SUPERFAMILY SSF46626 21 116 7.45E-21 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c17520 d0104b9a8054b4edeaae112a1456fe24 264 Gene3D G3DSA:1.10.760.10 13 124 1.1E-26 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c14900 ef403d4e1fc0024762f9d87bf3eb3a46 350 SUPERFAMILY SSF52540 93 338 2.58E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c14900 ef403d4e1fc0024762f9d87bf3eb3a46 350 ProSitePatterns PS01215 Mrp family signature. 199 215 - T 12-10-2018 IPR000808 Mrp, conserved site GO:0005524 TSC_c14900 ef403d4e1fc0024762f9d87bf3eb3a46 350 Gene3D G3DSA:3.30.300.130 1 85 7.6E-21 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSC_c14900 ef403d4e1fc0024762f9d87bf3eb3a46 350 Gene3D G3DSA:3.40.50.300 86 334 5.6E-83 T 12-10-2018 TSC_c14900 ef403d4e1fc0024762f9d87bf3eb3a46 350 Pfam PF01883 Iron-sulfur cluster assembly protein 5 73 5.8E-21 T 12-10-2018 IPR002744 MIP18 family-like TSC_c14900 ef403d4e1fc0024762f9d87bf3eb3a46 350 SUPERFAMILY SSF117916 1 79 1.8E-22 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSC_c14900 ef403d4e1fc0024762f9d87bf3eb3a46 350 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 92 335 5.5E-98 T 12-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 TSC_c14900 ef403d4e1fc0024762f9d87bf3eb3a46 350 Hamap MF_02040 Iron-sulfur cluster carrier protein. 87 336 37.572 T 12-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein TSC_c05710 25c3d5e5b9dd181684f7e1536e57b598 48 Pfam PF00468 Ribosomal protein L34 1 43 1.8E-23 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c05710 25c3d5e5b9dd181684f7e1536e57b598 48 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.783 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c05710 25c3d5e5b9dd181684f7e1536e57b598 48 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 12-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c05710 25c3d5e5b9dd181684f7e1536e57b598 48 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 43 3.8E-21 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c05710 25c3d5e5b9dd181684f7e1536e57b598 48 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 39 7.0E-14 T 12-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c21270 23302d4c30d34499dc06ad7756d1cdc2 651 Gene3D G3DSA:3.30.200.20 87 176 4.8E-29 T 12-10-2018 TSC_c21270 23302d4c30d34499dc06ad7756d1cdc2 651 SMART SM00220 97 364 1.2E-73 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TSC_c21270 23302d4c30d34499dc06ad7756d1cdc2 651 SUPERFAMILY SSF56112 90 357 4.32E-81 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TSC_c21270 23302d4c30d34499dc06ad7756d1cdc2 651 Gene3D G3DSA:2.120.10.30 445 600 3.5E-18 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TSC_c21270 23302d4c30d34499dc06ad7756d1cdc2 651 Pfam PF00069 Protein kinase domain 97 357 2.0E-55 T 12-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 TSC_c21270 23302d4c30d34499dc06ad7756d1cdc2 651 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 103 126 - T 12-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 TSC_c21270 23302d4c30d34499dc06ad7756d1cdc2 651 Gene3D G3DSA:1.10.510.10 177 369 4.4E-49 T 12-10-2018 TSC_c21270 23302d4c30d34499dc06ad7756d1cdc2 651 SUPERFAMILY SSF63825 381 635 1.15E-20 T 12-10-2018 TSC_c21270 23302d4c30d34499dc06ad7756d1cdc2 651 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 215 227 - T 12-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 TSC_c20670 261a377345356119524f75798c66cbda 207 Gene3D G3DSA:3.30.70.2830 94 207 3.4E-48 T 12-10-2018 TSC_c06340 6fc11aec38dfd5bc7bae95d0f4a82fc9 377 SUPERFAMILY SSF48256 4 376 1.96E-129 T 12-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 TSC_c06340 6fc11aec38dfd5bc7bae95d0f4a82fc9 377 PRINTS PR00143 Citrate synthase signature 328 342 2.0E-41 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TSC_c06340 6fc11aec38dfd5bc7bae95d0f4a82fc9 377 PRINTS PR00143 Citrate synthase signature 195 223 2.0E-41 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TSC_c06340 6fc11aec38dfd5bc7bae95d0f4a82fc9 377 PRINTS PR00143 Citrate synthase signature 173 188 2.0E-41 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TSC_c06340 6fc11aec38dfd5bc7bae95d0f4a82fc9 377 PRINTS PR00143 Citrate synthase signature 308 324 2.0E-41 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TSC_c06340 6fc11aec38dfd5bc7bae95d0f4a82fc9 377 PRINTS PR00143 Citrate synthase signature 248 268 2.0E-41 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TSC_c06340 6fc11aec38dfd5bc7bae95d0f4a82fc9 377 PRINTS PR00143 Citrate synthase signature 124 137 2.0E-41 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TSC_c06340 6fc11aec38dfd5bc7bae95d0f4a82fc9 377 Pfam PF00285 Citrate synthase, C-terminal domain 6 358 9.4E-126 T 12-10-2018 IPR002020 Citrate synthase GO:0046912 TSC_c06340 6fc11aec38dfd5bc7bae95d0f4a82fc9 377 Gene3D G3DSA:1.10.230.10 221 322 7.8E-142 T 12-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain TSC_c06340 6fc11aec38dfd5bc7bae95d0f4a82fc9 377 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 376 5.1E-146 T 12-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 TSC_c06340 6fc11aec38dfd5bc7bae95d0f4a82fc9 377 PIRSF PIRSF001369 1 377 4.8E-155 T 12-10-2018 IPR024176 Citrate synthase, bacterial-type TSC_c06340 6fc11aec38dfd5bc7bae95d0f4a82fc9 377 Gene3D G3DSA:1.10.580.10 20 347 7.8E-142 T 12-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 TSC_c10210 9a7bf1a58dc775471565bdf211752d43 277 Pfam PF02653 Branched-chain amino acid transport system / permease component 7 257 6.4E-31 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSC_c18590 8e74a4be76548173aeaf1e832a7342a7 351 SUPERFAMILY SSF55120 12 337 3.74E-88 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c18590 8e74a4be76548173aeaf1e832a7342a7 351 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 9 339 26.152 T 12-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c18590 8e74a4be76548173aeaf1e832a7342a7 351 Gene3D G3DSA:3.30.2350.20 22 334 3.7E-90 T 12-10-2018 TSC_c18590 8e74a4be76548173aeaf1e832a7342a7 351 Gene3D G3DSA:3.30.2340.10 170 299 3.7E-90 T 12-10-2018 TSC_c18590 8e74a4be76548173aeaf1e832a7342a7 351 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 12 171 1.3E-46 T 12-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c18590 8e74a4be76548173aeaf1e832a7342a7 351 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 193 334 9.5E-27 T 12-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c11740 3161716a592e33afb668fd725f71f569 250 Gene3D G3DSA:3.30.950.10 115 238 1.9E-36 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TSC_c11740 3161716a592e33afb668fd725f71f569 250 Gene3D G3DSA:3.40.1010.10 1 114 1.3E-41 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TSC_c11740 3161716a592e33afb668fd725f71f569 250 SUPERFAMILY SSF53790 1 225 2.22E-57 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TSC_c11740 3161716a592e33afb668fd725f71f569 250 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TSC_c11740 3161716a592e33afb668fd725f71f569 250 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 205 5.7E-42 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TSC_c11740 3161716a592e33afb668fd725f71f569 250 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 225 2.7E-71 T 12-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TSC_c11740 3161716a592e33afb668fd725f71f569 250 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 79 112 - T 12-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 TSC_c19190 ac189f6c075826a80b58b1b064b0a253 496 PIRSF PIRSF000538 1 496 4.8E-175 T 12-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TSC_c19190 ac189f6c075826a80b58b1b064b0a253 496 Gene3D G3DSA:3.30.420.40 1 250 2.5E-111 T 12-10-2018 TSC_c19190 ac189f6c075826a80b58b1b064b0a253 496 SUPERFAMILY SSF53067 1 250 6.91E-94 T 12-10-2018 TSC_c19190 ac189f6c075826a80b58b1b064b0a253 496 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 358 378 - T 12-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 TSC_c19190 ac189f6c075826a80b58b1b064b0a253 496 SUPERFAMILY SSF53067 252 492 3.18E-75 T 12-10-2018 TSC_c19190 ac189f6c075826a80b58b1b064b0a253 496 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 3 249 3.8E-75 T 12-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 TSC_c19190 ac189f6c075826a80b58b1b064b0a253 496 Hamap MF_00186 Glycerol kinase [glpK]. 1 492 56.184 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 TSC_c19190 ac189f6c075826a80b58b1b064b0a253 496 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 259 446 2.5E-59 T 12-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 TSC_c19190 ac189f6c075826a80b58b1b064b0a253 496 Gene3D G3DSA:3.30.420.40 251 495 1.7E-86 T 12-10-2018 TSC_c19190 ac189f6c075826a80b58b1b064b0a253 496 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 2 491 1.3E-206 T 12-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 TSC_c24610 994dcce633d6146cdcafc783d270dd66 116 SMART SM00938 4 105 1.0E-43 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSC_c24610 994dcce633d6146cdcafc783d270dd66 116 SUPERFAMILY SSF54913 1 112 1.78E-36 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TSC_c24610 994dcce633d6146cdcafc783d270dd66 116 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 2.4E-33 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSC_c24610 994dcce633d6146cdcafc783d270dd66 116 Gene3D G3DSA:3.30.70.120 1 116 1.6E-42 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TSC_c24610 994dcce633d6146cdcafc783d270dd66 116 PRINTS PR00340 P-II protein signature 23 41 4.2E-22 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSC_c24610 994dcce633d6146cdcafc783d270dd66 116 PRINTS PR00340 P-II protein signature 52 75 4.2E-22 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSC_c24610 994dcce633d6146cdcafc783d270dd66 116 PRINTS PR00340 P-II protein signature 2 17 4.2E-22 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSC_c24610 994dcce633d6146cdcafc783d270dd66 116 PRINTS PR00340 P-II protein signature 83 103 4.2E-22 T 12-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 TSC_c24610 994dcce633d6146cdcafc783d270dd66 116 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 12-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 PRINTS PR00906 SecA protein signature 60 84 1.5E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 PRINTS PR00906 SecA protein signature 370 387 1.5E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 PRINTS PR00906 SecA protein signature 114 124 1.5E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 PRINTS PR00906 SecA protein signature 407 420 1.5E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 PRINTS PR00906 SecA protein signature 98 112 1.5E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 PRINTS PR00906 SecA protein signature 167 187 1.5E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 PRINTS PR00906 SecA protein signature 333 355 1.5E-67 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 SMART SM00957 5 396 4.0E-268 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 SUPERFAMILY SSF81886 727 942 5.62E-70 T 12-10-2018 IPR036266 SecA, Wing/Scaffold superfamily TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 SMART SM00958 228 352 3.7E-71 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 Gene3D G3DSA:3.40.50.300 21 409 9.2E-176 T 12-10-2018 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 ProSitePatterns PS01312 SecA family signature. 570 585 - T 12-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 28 467 8.7E-202 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 SUPERFAMILY SSF52540 4 409 4.37E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 Gene3D G3DSA:1.10.3060.10 728 940 4.0E-66 T 12-10-2018 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 Pfam PF01043 SecA preprotein cross-linking domain 232 352 8.7E-39 T 12-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 Pfam PF07516 SecA Wing and Scaffold domain 724 936 1.1E-64 T 12-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 SUPERFAMILY SSF52540 410 725 7.69E-53 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 SUPERFAMILY SSF81767 227 362 1.57E-43 T 12-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 939 19.88 T 12-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 Pfam PF07517 SecA DEAD-like domain 6 396 1.3E-121 T 12-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 TSC_c18140 c31f40ad8d01e746b6aa59b26abb0f7a 998 Gene3D G3DSA:3.90.1440.10 229 362 9.2E-176 T 12-10-2018 TSC_c09650 a2a4ad4568fc4bf921c79137d1ad096a 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 22.481 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c09650 a2a4ad4568fc4bf921c79137d1ad096a 89 SMART SM01387 8 88 2.6E-49 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c09650 a2a4ad4568fc4bf921c79137d1ad096a 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c09650 a2a4ad4568fc4bf921c79137d1ad096a 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 4.0E-36 T 12-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c09650 a2a4ad4568fc4bf921c79137d1ad096a 89 Gene3D G3DSA:1.10.287.10 1 89 3.5E-37 T 12-10-2018 TSC_c09650 a2a4ad4568fc4bf921c79137d1ad096a 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 1.0E-16 T 12-10-2018 TSC_c09650 a2a4ad4568fc4bf921c79137d1ad096a 89 Pfam PF00312 Ribosomal protein S15 8 88 3.8E-36 T 12-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c09650 a2a4ad4568fc4bf921c79137d1ad096a 89 SUPERFAMILY SSF47060 3 89 1.68E-34 T 12-10-2018 IPR009068 S15/NS1, RNA-binding TSC_c04110 b73f35edabf86cd831dde8b3e68f76fd 346 Pfam PF07690 Major Facilitator Superfamily 8 306 1.7E-13 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c04110 b73f35edabf86cd831dde8b3e68f76fd 346 Gene3D G3DSA:1.20.1250.20 1 176 2.3E-10 T 12-10-2018 TSC_c04110 b73f35edabf86cd831dde8b3e68f76fd 346 SUPERFAMILY SSF103473 2 335 4.97E-24 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c04110 b73f35edabf86cd831dde8b3e68f76fd 346 Gene3D G3DSA:1.20.1250.20 177 340 2.3E-12 T 12-10-2018 TSC_c01970 121b60ec18f7a62cd40b3a483c7d4032 281 SUPERFAMILY SSF52402 10 262 3.31E-66 T 12-10-2018 TSC_c01970 121b60ec18f7a62cd40b3a483c7d4032 281 Pfam PF02540 NAD synthase 24 259 2.6E-62 T 12-10-2018 IPR022310 NAD/GMP synthase TSC_c01970 121b60ec18f7a62cd40b3a483c7d4032 281 TIGRFAM TIGR00552 nadE: NAD+ synthetase 24 260 2.5E-59 T 12-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 TSC_c01970 121b60ec18f7a62cd40b3a483c7d4032 281 Gene3D G3DSA:3.40.50.620 15 263 3.5E-70 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c24400 629c5373ba9773f0acefaa28e229ee40 91 Gene3D G3DSA:2.10.260.10 8 49 2.8E-11 T 12-10-2018 TSC_c24400 629c5373ba9773f0acefaa28e229ee40 91 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 12 51 2.3E-13 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TSC_c24400 629c5373ba9773f0acefaa28e229ee40 91 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 12 41 3.3E-10 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TSC_c24400 629c5373ba9773f0acefaa28e229ee40 91 SMART SM00966 12 58 2.2E-9 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TSC_c24400 629c5373ba9773f0acefaa28e229ee40 91 SUPERFAMILY SSF89447 8 47 9.81E-11 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily TSC_c18120 65c2de9f2498900f089ec3770fbc2f80 511 SUPERFAMILY SSF51735 369 497 2.56E-21 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c18120 65c2de9f2498900f089ec3770fbc2f80 511 Pfam PF00999 Sodium/hydrogen exchanger family 4 328 2.3E-28 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TSC_c18120 65c2de9f2498900f089ec3770fbc2f80 511 Pfam PF02254 TrkA-N domain 369 480 4.5E-16 T 12-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 TSC_c18120 65c2de9f2498900f089ec3770fbc2f80 511 Gene3D G3DSA:3.40.50.720 364 503 2.4E-31 T 12-10-2018 TSC_c18120 65c2de9f2498900f089ec3770fbc2f80 511 Gene3D G3DSA:1.20.1530.20 3 344 2.1E-40 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily TSC_c08880 d3080aa03a6e9c89ee3344f962535b85 430 Gene3D G3DSA:3.10.580.10 189 342 5.6E-59 T 12-10-2018 TSC_c08880 d3080aa03a6e9c89ee3344f962535b85 430 Pfam PF03471 Transporter associated domain 348 423 2.6E-26 T 12-10-2018 IPR005170 Transporter-associated domain TSC_c08880 d3080aa03a6e9c89ee3344f962535b85 430 Pfam PF01595 Domain of unknown function DUF21 21 195 2.8E-46 T 12-10-2018 IPR002550 CNNM, transmembrane domain TSC_c08880 d3080aa03a6e9c89ee3344f962535b85 430 Pfam PF00571 CBS domain 210 266 1.1E-7 T 12-10-2018 IPR000644 CBS domain TSC_c08880 d3080aa03a6e9c89ee3344f962535b85 430 Pfam PF00571 CBS domain 280 331 1.5E-6 T 12-10-2018 IPR000644 CBS domain TSC_c08880 d3080aa03a6e9c89ee3344f962535b85 430 SMART SM01091 347 425 2.6E-33 T 12-10-2018 IPR005170 Transporter-associated domain TSC_c08880 d3080aa03a6e9c89ee3344f962535b85 430 SUPERFAMILY SSF54631 205 345 7.55E-37 T 12-10-2018 TSC_c08880 d3080aa03a6e9c89ee3344f962535b85 430 Gene3D G3DSA:3.30.465.10 345 425 2.9E-27 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSC_c08880 d3080aa03a6e9c89ee3344f962535b85 430 SMART SM00116 283 331 7.3 T 12-10-2018 IPR000644 CBS domain TSC_c08880 d3080aa03a6e9c89ee3344f962535b85 430 SMART SM00116 219 268 0.12 T 12-10-2018 IPR000644 CBS domain TSC_c08880 d3080aa03a6e9c89ee3344f962535b85 430 SUPERFAMILY SSF56176 346 427 4.09E-25 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSC_c14770 95a802cd7bc4cfba01ee3e678e068f10 342 Gene3D G3DSA:1.10.3470.10 9 342 6.4E-93 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TSC_c14770 95a802cd7bc4cfba01ee3e678e068f10 342 SUPERFAMILY SSF81345 6 338 2.09E-78 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TSC_c14770 95a802cd7bc4cfba01ee3e678e068f10 342 Pfam PF01032 FecCD transport family 21 337 8.8E-86 T 12-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 TSC_c07490 f6cea3c844fd44620505c952479afa5e 102 Pfam PF01638 HxlR-like helix-turn-helix 21 95 1.0E-18 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type TSC_c07490 f6cea3c844fd44620505c952479afa5e 102 Gene3D G3DSA:1.10.10.10 4 101 1.4E-24 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c07490 f6cea3c844fd44620505c952479afa5e 102 SUPERFAMILY SSF46785 7 92 7.68E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c15870 a79c6b64f19fb14c75fd2e2600706904 343 Gene3D G3DSA:3.90.1150.10 3 328 4.2E-80 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c15870 a79c6b64f19fb14c75fd2e2600706904 343 Gene3D G3DSA:3.40.640.10 12 248 4.2E-80 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c15870 a79c6b64f19fb14c75fd2e2600706904 343 SUPERFAMILY SSF53383 3 328 4.68E-65 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c15870 a79c6b64f19fb14c75fd2e2600706904 343 PIRSF PIRSF000524 1 342 2.6E-64 T 12-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 TSC_c15870 a79c6b64f19fb14c75fd2e2600706904 343 Pfam PF00266 Aminotransferase class-V 19 287 9.0E-17 T 12-10-2018 IPR000192 Aminotransferase class V domain TSC_c07230 35251ed2388687bd90df068a76e97e8c 178 SMART SM00867 2 170 3.0E-65 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TSC_c07230 35251ed2388687bd90df068a76e97e8c 178 SUPERFAMILY SSF101874 2 172 1.1E-55 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily TSC_c07230 35251ed2388687bd90df068a76e97e8c 178 Pfam PF04264 YceI-like domain 3 169 5.7E-40 T 12-10-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like TSC_c07230 35251ed2388687bd90df068a76e97e8c 178 Gene3D G3DSA:2.40.128.110 1 178 5.6E-55 T 12-10-2018 IPR036761 Lipid/polyisoprenoid-binding, YceI-like superfamily TSC_c05920 0055e1b2c9e772a22b758d0b09ed1e68 426 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 1 420 15.961 T 12-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 TSC_c05920 0055e1b2c9e772a22b758d0b09ed1e68 426 Pfam PF00361 Proton-conducting membrane transporter 102 371 2.4E-58 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c19360 6b90fbba23d85a73a3771fb217f65ce8 95 Pfam PF08734 GYD domain 4 91 2.2E-27 T 12-10-2018 IPR014845 Protein GYD/TTHA1554 TSC_c21070 09e140270ae428316705fab5c89b0e4d 553 Gene3D G3DSA:3.90.780.10 354 553 1.7E-80 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c21070 09e140270ae428316705fab5c89b0e4d 553 Gene3D G3DSA:3.60.21.10 77 353 1.2E-88 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TSC_c21070 09e140270ae428316705fab5c89b0e4d 553 Pfam PF02872 5'-nucleotidase, C-terminal domain 386 497 3.9E-13 T 12-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c21070 09e140270ae428316705fab5c89b0e4d 553 PRINTS PR01607 Apyrase family signature 18 36 4.8E-9 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c21070 09e140270ae428316705fab5c89b0e4d 553 PRINTS PR01607 Apyrase family signature 244 261 4.8E-9 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c21070 09e140270ae428316705fab5c89b0e4d 553 PRINTS PR01607 Apyrase family signature 263 286 4.8E-9 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c21070 09e140270ae428316705fab5c89b0e4d 553 PRINTS PR01607 Apyrase family signature 291 311 4.8E-9 T 12-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c21070 09e140270ae428316705fab5c89b0e4d 553 SUPERFAMILY SSF55816 353 543 2.49E-26 T 12-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 TSC_c21070 09e140270ae428316705fab5c89b0e4d 553 TIGRFAM TIGR04486 thiosulf_SoxB: thiosulfohydrolase SoxB 6 543 1.0E-210 T 12-10-2018 IPR030998 Thiosulfohydrolase SoxB TSC_c21070 09e140270ae428316705fab5c89b0e4d 553 SUPERFAMILY SSF56300 16 350 1.99E-60 T 12-10-2018 TSC_c13910 33d5b9bb22befb1eb292ac01c41e01f8 449 Pfam PF01769 Divalent cation transporter 319 439 4.3E-27 T 12-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 TSC_c13910 33d5b9bb22befb1eb292ac01c41e01f8 449 TIGRFAM TIGR00400 mgtE: magnesium transporter 11 446 1.2E-121 T 12-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 TSC_c13910 33d5b9bb22befb1eb292ac01c41e01f8 449 Pfam PF03448 MgtE intracellular N domain 28 131 9.7E-23 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain TSC_c13910 33d5b9bb22befb1eb292ac01c41e01f8 449 Gene3D G3DSA:3.10.580.10 129 251 3.3E-52 T 12-10-2018 TSC_c13910 33d5b9bb22befb1eb292ac01c41e01f8 449 Gene3D G3DSA:1.10.357.20 270 447 1.1E-60 T 12-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain TSC_c13910 33d5b9bb22befb1eb292ac01c41e01f8 449 SUPERFAMILY SSF54631 133 265 1.07E-39 T 12-10-2018 TSC_c13910 33d5b9bb22befb1eb292ac01c41e01f8 449 SUPERFAMILY SSF161093 277 446 1.44E-46 T 12-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 TSC_c13910 33d5b9bb22befb1eb292ac01c41e01f8 449 SUPERFAMILY SSF158791 8 130 3.4E-25 T 12-10-2018 TSC_c13910 33d5b9bb22befb1eb292ac01c41e01f8 449 SMART SM00116 140 193 3.4E-5 T 12-10-2018 IPR000644 CBS domain TSC_c13910 33d5b9bb22befb1eb292ac01c41e01f8 449 SMART SM00116 204 252 7.8E-9 T 12-10-2018 IPR000644 CBS domain TSC_c13910 33d5b9bb22befb1eb292ac01c41e01f8 449 SMART SM00924 27 133 3.0E-24 T 12-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain TSC_c13910 33d5b9bb22befb1eb292ac01c41e01f8 449 Pfam PF00571 CBS domain 197 252 9.6E-13 T 12-10-2018 IPR000644 CBS domain TSC_c13910 33d5b9bb22befb1eb292ac01c41e01f8 449 Pfam PF00571 CBS domain 134 191 3.5E-11 T 12-10-2018 IPR000644 CBS domain TSC_c13910 33d5b9bb22befb1eb292ac01c41e01f8 449 Gene3D G3DSA:1.25.60.10 2 128 1.5E-36 T 12-10-2018 IPR038076 MgtE, N-terminal domain superfamily TSC_c16720 a7d2fdf75928990f6b51fedb4d694c46 299 SUPERFAMILY SSF47240 14 280 2.79E-46 T 12-10-2018 IPR009078 Ferritin-like superfamily TSC_c16720 a7d2fdf75928990f6b51fedb4d694c46 299 Pfam PF00268 Ribonucleotide reductase, small chain 19 266 1.1E-20 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSC_c16720 a7d2fdf75928990f6b51fedb4d694c46 299 Gene3D G3DSA:1.10.620.20 1 295 2.3E-99 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 TSC_c22170 a37e674005cb36454469511623577a9a 313 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 222 2.4E-24 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c22170 a37e674005cb36454469511623577a9a 313 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 244 305 4.6E-17 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c22170 a37e674005cb36454469511623577a9a 313 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 59 154 9.2E-25 T 12-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c22170 a37e674005cb36454469511623577a9a 313 Gene3D G3DSA:3.30.1360.10 19 222 4.4E-90 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c22170 a37e674005cb36454469511623577a9a 313 SMART SM00662 20 228 3.2E-100 T 12-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c22170 a37e674005cb36454469511623577a9a 313 SUPERFAMILY SSF56553 50 172 1.96E-41 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c22170 a37e674005cb36454469511623577a9a 313 Gene3D G3DSA:2.170.120.12 50 171 4.4E-90 T 12-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c22170 a37e674005cb36454469511623577a9a 313 SUPERFAMILY SSF47789 250 312 2.22E-14 T 12-10-2018 TSC_c22170 a37e674005cb36454469511623577a9a 313 Gene3D G3DSA:1.10.150.20 245 313 7.5E-21 T 12-10-2018 TSC_c22170 a37e674005cb36454469511623577a9a 313 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 260 313 3.0E-13 T 12-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c22170 a37e674005cb36454469511623577a9a 313 SUPERFAMILY SSF55257 2 227 4.91E-32 T 12-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c22170 a37e674005cb36454469511623577a9a 313 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 312 1.4E-97 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c22170 a37e674005cb36454469511623577a9a 313 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 2 313 33.102 T 12-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c05160 b624419d17e65c4ea3efdf0d195be0f8 567 SMART SM01340 217 334 1.8E-20 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 TSC_c05160 b624419d17e65c4ea3efdf0d195be0f8 567 Gene3D G3DSA:3.30.565.10 1 210 1.1E-28 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c05160 b624419d17e65c4ea3efdf0d195be0f8 567 Pfam PF08676 MutL C terminal dimerisation domain 362 497 4.4E-29 T 12-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 TSC_c05160 b624419d17e65c4ea3efdf0d195be0f8 567 SUPERFAMILY SSF55874 2 210 3.64E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c05160 b624419d17e65c4ea3efdf0d195be0f8 567 Gene3D G3DSA:2.30.42.20 365 539 1.0E-45 T 12-10-2018 TSC_c05160 b624419d17e65c4ea3efdf0d195be0f8 567 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 22 127 2.7E-7 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c05160 b624419d17e65c4ea3efdf0d195be0f8 567 SMART SM00853 364 497 9.9E-34 T 12-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 TSC_c05160 b624419d17e65c4ea3efdf0d195be0f8 567 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 220 332 1.4E-15 T 12-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 TSC_c05160 b624419d17e65c4ea3efdf0d195be0f8 567 Gene3D G3DSA:3.30.230.10 222 332 3.4E-11 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSC_c05160 b624419d17e65c4ea3efdf0d195be0f8 567 SUPERFAMILY SSF54211 207 333 1.21E-14 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c05160 b624419d17e65c4ea3efdf0d195be0f8 567 Gene3D G3DSA:3.30.1370.100 406 494 1.0E-45 T 12-10-2018 TSC_c05160 b624419d17e65c4ea3efdf0d195be0f8 567 SUPERFAMILY SSF118116 360 539 1.57E-39 T 12-10-2018 IPR037198 MutL, C-terminal domain superfamily TSC_c21610 57297cc99e40d256f5d3778815ebf32a 216 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 15 213 2.0E-51 T 12-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 TSC_c21610 57297cc99e40d256f5d3778815ebf32a 216 Pfam PF03006 Haemolysin-III related 12 208 5.6E-37 T 12-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 TSC_c24720 1700c0967d187ad53a1b9ac9b405007e 373 PIRSF PIRSF000729 10 371 3.5E-126 T 12-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 TSC_c24720 1700c0967d187ad53a1b9ac9b405007e 373 SUPERFAMILY SSF88697 278 368 1.05E-23 T 12-10-2018 IPR015947 PUA-like superfamily TSC_c24720 1700c0967d187ad53a1b9ac9b405007e 373 Pfam PF01472 PUA domain 279 352 1.0E-23 T 12-10-2018 IPR002478 PUA domain GO:0003723 TSC_c24720 1700c0967d187ad53a1b9ac9b405007e 373 Hamap MF_00456 Glutamate 5-kinase [proB]. 14 262 35.847 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TSC_c24720 1700c0967d187ad53a1b9ac9b405007e 373 ProSitePatterns PS00902 Glutamate 5-kinase signature. 210 227 - T 12-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TSC_c24720 1700c0967d187ad53a1b9ac9b405007e 373 PRINTS PR00474 Glutamate 5-kinase family signature 212 232 1.4E-39 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TSC_c24720 1700c0967d187ad53a1b9ac9b405007e 373 PRINTS PR00474 Glutamate 5-kinase family signature 50 64 1.4E-39 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TSC_c24720 1700c0967d187ad53a1b9ac9b405007e 373 PRINTS PR00474 Glutamate 5-kinase family signature 153 180 1.4E-39 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TSC_c24720 1700c0967d187ad53a1b9ac9b405007e 373 PRINTS PR00474 Glutamate 5-kinase family signature 121 142 1.4E-39 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TSC_c24720 1700c0967d187ad53a1b9ac9b405007e 373 Pfam PF00696 Amino acid kinase family 14 235 6.1E-39 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSC_c24720 1700c0967d187ad53a1b9ac9b405007e 373 SUPERFAMILY SSF53633 14 259 2.88E-61 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSC_c24720 1700c0967d187ad53a1b9ac9b405007e 373 Gene3D G3DSA:2.30.130.10 268 370 9.1E-35 T 12-10-2018 IPR036974 PUA domain superfamily GO:0003723 TSC_c24720 1700c0967d187ad53a1b9ac9b405007e 373 SMART SM00359 279 362 8.3E-25 T 12-10-2018 IPR002478 PUA domain GO:0003723 TSC_c24720 1700c0967d187ad53a1b9ac9b405007e 373 Gene3D G3DSA:3.40.1160.10 11 265 7.4E-80 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSC_c24720 1700c0967d187ad53a1b9ac9b405007e 373 TIGRFAM TIGR01027 proB: glutamate 5-kinase 14 368 1.3E-132 T 12-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TSC_c09470 7986c7c149ff00f65d4dd447a05ca583 431 SUPERFAMILY SSF81891 128 424 5.49E-46 T 12-10-2018 TSC_c09470 7986c7c149ff00f65d4dd447a05ca583 431 TIGRFAM TIGR00277 HDIG: HDIG domain 220 304 2.0E-13 T 12-10-2018 IPR006675 HDIG domain TSC_c09470 7986c7c149ff00f65d4dd447a05ca583 431 SMART SM00471 225 358 5.0E-8 T 12-10-2018 IPR003607 HD/PDEase domain TSC_c09470 7986c7c149ff00f65d4dd447a05ca583 431 Pfam PF01743 Poly A polymerase head domain 21 73 5.0E-5 T 12-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 TSC_c09470 7986c7c149ff00f65d4dd447a05ca583 431 Gene3D G3DSA:1.10.3090.10 121 415 7.6E-33 T 12-10-2018 TSC_c09470 7986c7c149ff00f65d4dd447a05ca583 431 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 176 213 4.9E-9 T 12-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 TSC_c09470 7986c7c149ff00f65d4dd447a05ca583 431 Pfam PF01966 HD domain 230 346 2.0E-12 T 12-10-2018 IPR006674 HD domain TSC_c09470 7986c7c149ff00f65d4dd447a05ca583 431 Gene3D G3DSA:3.30.460.10 13 119 3.6E-14 T 12-10-2018 TSC_c09470 7986c7c149ff00f65d4dd447a05ca583 431 SUPERFAMILY SSF81301 16 120 1.74E-16 T 12-10-2018 TSC_c03740 64b4b58568fee91d5e272eb12b75d5c6 468 SUPERFAMILY SSF49503 170 284 1.82E-20 T 12-10-2018 IPR008972 Cupredoxin TSC_c03740 64b4b58568fee91d5e272eb12b75d5c6 468 Pfam PF00394 Multicopper oxidase 195 285 5.1E-10 T 12-10-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 TSC_c03740 64b4b58568fee91d5e272eb12b75d5c6 468 Gene3D G3DSA:2.60.40.420 159 337 2.1E-50 T 12-10-2018 IPR008972 Cupredoxin TSC_c03740 64b4b58568fee91d5e272eb12b75d5c6 468 Pfam PF07732 Multicopper oxidase 51 159 2.4E-25 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 TSC_c03740 64b4b58568fee91d5e272eb12b75d5c6 468 Gene3D G3DSA:2.60.40.420 341 468 4.0E-40 T 12-10-2018 IPR008972 Cupredoxin TSC_c03740 64b4b58568fee91d5e272eb12b75d5c6 468 Pfam PF07731 Multicopper oxidase 353 466 1.7E-22 T 12-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 TSC_c03740 64b4b58568fee91d5e272eb12b75d5c6 468 SUPERFAMILY SSF49503 316 467 5.71E-28 T 12-10-2018 IPR008972 Cupredoxin TSC_c03740 64b4b58568fee91d5e272eb12b75d5c6 468 SUPERFAMILY SSF49503 25 159 1.16E-30 T 12-10-2018 IPR008972 Cupredoxin TSC_c03740 64b4b58568fee91d5e272eb12b75d5c6 468 Gene3D G3DSA:2.60.40.420 25 157 2.9E-41 T 12-10-2018 IPR008972 Cupredoxin TSC_c03740 64b4b58568fee91d5e272eb12b75d5c6 468 ProSitePatterns PS00080 Multicopper oxidases signature 2. 450 461 - T 12-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 TSC_c21490 50ec8d480656ec4e6a1bc21ab76e8b69 142 Gene3D G3DSA:3.10.690.10 1 136 8.8E-47 T 12-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 TSC_c21490 50ec8d480656ec4e6a1bc21ab76e8b69 142 SUPERFAMILY SSF103256 6 131 3.4E-41 T 12-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 TSC_c21490 50ec8d480656ec4e6a1bc21ab76e8b69 142 Pfam PF02577 Bifunctional nuclease 5 130 5.9E-44 T 12-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 TSC_c22610 9467aba7e85936a972bdcff10e557afc 222 Pfam PF02592 Putative vitamin uptake transporter 35 196 1.2E-49 T 12-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 TSC_c22610 9467aba7e85936a972bdcff10e557afc 222 Hamap MF_02088 Probable queuosine precursor transporter. 1 209 17.107 T 12-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 TSC_c22610 9467aba7e85936a972bdcff10e557afc 222 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 8 202 2.4E-42 T 12-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 TSC_c08630 bae1f701dd4011e68f87a343416884d7 363 SUPERFAMILY SSF143100 11 73 3.27E-6 T 12-10-2018 IPR035069 TTHA1013/TTHA0281-like TSC_c08630 bae1f701dd4011e68f87a343416884d7 363 Gene3D G3DSA:3.30.160.250 3 80 3.0E-13 T 12-10-2018 TSC_c08630 bae1f701dd4011e68f87a343416884d7 363 SUPERFAMILY SSF52980 117 357 1.55E-29 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSC_c08630 bae1f701dd4011e68f87a343416884d7 363 Gene3D G3DSA:3.40.1350.10 242 350 4.4E-9 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TSC_c08630 bae1f701dd4011e68f87a343416884d7 363 Gene3D G3DSA:1.10.10.680 181 241 4.4E-9 T 12-10-2018 TSC_c18430 4eaffe41ec99635dcb82eb46106122c4 951 SUPERFAMILY SSF117074 677 740 4.05E-9 T 12-10-2018 TSC_c18430 4eaffe41ec99635dcb82eb46106122c4 951 Gene3D G3DSA:2.60.40.10 584 659 7.6E-7 T 12-10-2018 IPR013783 Immunoglobulin-like fold TSC_c18430 4eaffe41ec99635dcb82eb46106122c4 951 Gene3D G3DSA:2.60.40.10 675 751 2.8E-9 T 12-10-2018 IPR013783 Immunoglobulin-like fold TSC_c18430 4eaffe41ec99635dcb82eb46106122c4 951 SUPERFAMILY SSF117074 586 643 1.44E-5 T 12-10-2018 TSC_c00610 25918949b5104dd3b680383aeeccdbdb 167 SUPERFAMILY SSF160387 43 149 1.57E-10 T 12-10-2018 TSC_c00610 25918949b5104dd3b680383aeeccdbdb 167 Pfam PF05573 NosL 28 143 3.2E-7 T 12-10-2018 IPR008719 Nitrous oxide reductase accessory protein NosL TSC_c12100 c264550d23430f750db584bd6ce3c786 323 SUPERFAMILY SSF47240 8 318 9.98E-49 T 12-10-2018 IPR009078 Ferritin-like superfamily TSC_c12100 c264550d23430f750db584bd6ce3c786 323 Pfam PF00268 Ribonucleotide reductase, small chain 9 279 1.1E-31 T 12-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSC_c12100 c264550d23430f750db584bd6ce3c786 323 Gene3D G3DSA:1.10.620.20 3 297 6.1E-42 T 12-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 TSC_c10460 6c6c5e7f99e73d8e231bb77743f9f07a 167 SMART SM00903 27 162 3.3E-46 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TSC_c10460 6c6c5e7f99e73d8e231bb77743f9f07a 167 Pfam PF01613 Flavin reductase like domain 28 163 4.9E-31 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TSC_c10460 6c6c5e7f99e73d8e231bb77743f9f07a 167 Gene3D G3DSA:2.30.110.10 19 167 2.0E-44 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TSC_c10460 6c6c5e7f99e73d8e231bb77743f9f07a 167 SUPERFAMILY SSF50475 20 163 5.4E-37 T 12-10-2018 TSC_c02480 1b6ff92588abc3accb2a75ec9aa85fac 667 Gene3D G3DSA:3.10.20.30 405 480 1.5E-35 T 12-10-2018 IPR012675 Beta-grasp domain superfamily TSC_c02480 1b6ff92588abc3accb2a75ec9aa85fac 667 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 29 648 3.9E-215 T 12-10-2018 IPR004811 RelA/SpoT family GO:0015969 TSC_c02480 1b6ff92588abc3accb2a75ec9aa85fac 667 Gene3D G3DSA:3.30.460.10 199 350 3.1E-46 T 12-10-2018 TSC_c02480 1b6ff92588abc3accb2a75ec9aa85fac 667 Pfam PF04607 Region found in RelA / SpoT proteins 247 369 3.2E-35 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 TSC_c02480 1b6ff92588abc3accb2a75ec9aa85fac 667 Pfam PF13328 HD domain 29 181 8.2E-53 T 12-10-2018 IPR003607 HD/PDEase domain TSC_c02480 1b6ff92588abc3accb2a75ec9aa85fac 667 Gene3D G3DSA:1.10.3210.10 5 197 8.5E-84 T 12-10-2018 TSC_c02480 1b6ff92588abc3accb2a75ec9aa85fac 667 SUPERFAMILY SSF81301 186 416 3.27E-60 T 12-10-2018 TSC_c02480 1b6ff92588abc3accb2a75ec9aa85fac 667 SUPERFAMILY SSF109604 11 197 8.79E-75 T 12-10-2018 TSC_c02480 1b6ff92588abc3accb2a75ec9aa85fac 667 SMART SM00471 44 159 2.1E-11 T 12-10-2018 IPR003607 HD/PDEase domain TSC_c02480 1b6ff92588abc3accb2a75ec9aa85fac 667 SMART SM00954 247 370 2.6E-66 T 12-10-2018 IPR007685 RelA/SpoT GO:0015969 TSC_c02480 1b6ff92588abc3accb2a75ec9aa85fac 667 SUPERFAMILY SSF81271 399 471 3.11E-23 T 12-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 TSC_c02480 1b6ff92588abc3accb2a75ec9aa85fac 667 Pfam PF02824 TGS domain 412 471 4.8E-24 T 12-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 TSC_c15570 bc24767c820057b9f98cde965b61db52 427 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 166 371 1.7E-22 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSC_c15570 bc24767c820057b9f98cde965b61db52 427 SMART SM00959 17 58 2.8E-11 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 TSC_c15570 bc24767c820057b9f98cde965b61db52 427 SUPERFAMILY SSF68912 14 58 1.69E-8 T 12-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily TSC_c15570 bc24767c820057b9f98cde965b61db52 427 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 427 193.256 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 TSC_c15570 bc24767c820057b9f98cde965b61db52 427 Pfam PF07498 Rho termination factor, N-terminal domain 17 58 6.9E-12 T 12-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 TSC_c15570 bc24767c820057b9f98cde965b61db52 427 Pfam PF07497 Rho termination factor, RNA-binding domain 63 135 1.2E-22 T 12-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 TSC_c15570 bc24767c820057b9f98cde965b61db52 427 TIGRFAM TIGR00767 rho: transcription termination factor Rho 16 424 2.5E-179 T 12-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 TSC_c15570 bc24767c820057b9f98cde965b61db52 427 SUPERFAMILY SSF52540 101 379 8.91E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c15570 bc24767c820057b9f98cde965b61db52 427 SUPERFAMILY SSF50249 63 135 1.88E-16 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c15570 bc24767c820057b9f98cde965b61db52 427 SMART SM00382 177 363 2.9E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c15570 bc24767c820057b9f98cde965b61db52 427 Gene3D G3DSA:2.40.50.140 12 139 1.1E-33 T 12-10-2018 TSC_c15570 bc24767c820057b9f98cde965b61db52 427 Gene3D G3DSA:3.40.50.300 140 427 5.1E-125 T 12-10-2018 TSC_c22310 7c9563c6dfde42ffa042b13f3662702c 61 SUPERFAMILY SSF57716 6 61 1.85E-21 T 12-10-2018 TSC_c22310 7c9563c6dfde42ffa042b13f3662702c 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 12-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22310 7c9563c6dfde42ffa042b13f3662702c 61 Pfam PF00253 Ribosomal protein S14p/S29e 10 60 8.2E-24 T 12-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22310 7c9563c6dfde42ffa042b13f3662702c 61 Gene3D G3DSA:4.10.830.10 1 61 4.7E-32 T 12-10-2018 TSC_c22310 7c9563c6dfde42ffa042b13f3662702c 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.669 T 12-10-2018 IPR023053 Ribosomal protein S14, type Z TSC_c11830 1098d257dadf395c48578ebd7264bbb3 320 Gene3D G3DSA:3.50.50.60 6 317 9.4E-44 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c11830 1098d257dadf395c48578ebd7264bbb3 320 SUPERFAMILY SSF51905 3 238 3.11E-22 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c11830 1098d257dadf395c48578ebd7264bbb3 320 Pfam PF01266 FAD dependent oxidoreductase 5 316 9.2E-37 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSC_c11830 1098d257dadf395c48578ebd7264bbb3 320 Gene3D G3DSA:3.30.9.10 87 281 9.4E-44 T 12-10-2018 TSC_c04090 993bedccc20e4f0a16be9b37e7f100a5 359 SUPERFAMILY SSF54826 3 123 3.54E-18 T 12-10-2018 TSC_c04090 993bedccc20e4f0a16be9b37e7f100a5 359 SMART SM00922 141 236 7.1E-16 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TSC_c04090 993bedccc20e4f0a16be9b37e7f100a5 359 SUPERFAMILY SSF51604 128 341 4.59E-40 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSC_c04090 993bedccc20e4f0a16be9b37e7f100a5 359 Gene3D G3DSA:3.30.390.10 4 115 4.5E-68 T 12-10-2018 IPR029017 Enolase-like, N-terminal TSC_c04090 993bedccc20e4f0a16be9b37e7f100a5 359 Gene3D G3DSA:3.20.20.120 116 336 4.5E-68 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSC_c04090 993bedccc20e4f0a16be9b37e7f100a5 359 Pfam PF13378 Enolase C-terminal domain-like 147 309 2.3E-27 T 12-10-2018 IPR029065 Enolase C-terminal domain-like TSC_c10860 0b0208b50681f0d17bf36f107eedd4eb 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 268 9.2E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c10860 0b0208b50681f0d17bf36f107eedd4eb 275 SUPERFAMILY SSF161098 6 275 2.8E-75 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c10860 0b0208b50681f0d17bf36f107eedd4eb 275 Gene3D G3DSA:1.10.3720.10 4 266 2.5E-69 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c22770 db7a5f2d28a81452db0e7bc6a6113885 344 Pfam PF00107 Zinc-binding dehydrogenase 177 303 4.6E-20 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSC_c22770 db7a5f2d28a81452db0e7bc6a6113885 344 SUPERFAMILY SSF50129 1 163 1.43E-44 T 12-10-2018 IPR011032 GroES-like superfamily TSC_c22770 db7a5f2d28a81452db0e7bc6a6113885 344 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TSC_c22770 db7a5f2d28a81452db0e7bc6a6113885 344 Pfam PF13823 Alcohol dehydrogenase GroES-associated 1 23 5.5E-11 T 12-10-2018 IPR027399 Alcohol dehydrogenase GroES-associated TSC_c22770 db7a5f2d28a81452db0e7bc6a6113885 344 SUPERFAMILY SSF51735 140 311 6.81E-34 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c22770 db7a5f2d28a81452db0e7bc6a6113885 344 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 132 7.8E-26 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSC_c22770 db7a5f2d28a81452db0e7bc6a6113885 344 Gene3D G3DSA:3.40.50.720 156 290 5.5E-100 T 12-10-2018 TSC_c22770 db7a5f2d28a81452db0e7bc6a6113885 344 Gene3D G3DSA:3.90.180.10 14 332 5.5E-100 T 12-10-2018 TSC_c08010 a03b7dea5a0b4aa27cfb13a4588fca9e 406 Pfam PF05193 Peptidase M16 inactive domain 165 336 2.3E-28 T 12-10-2018 IPR007863 Peptidase M16, C-terminal TSC_c08010 a03b7dea5a0b4aa27cfb13a4588fca9e 406 SUPERFAMILY SSF63411 234 399 1.42E-28 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TSC_c08010 a03b7dea5a0b4aa27cfb13a4588fca9e 406 Gene3D G3DSA:3.30.830.10 224 406 1.9E-40 T 12-10-2018 TSC_c08010 a03b7dea5a0b4aa27cfb13a4588fca9e 406 Gene3D G3DSA:3.30.830.10 1 212 5.5E-80 T 12-10-2018 TSC_c08010 a03b7dea5a0b4aa27cfb13a4588fca9e 406 SUPERFAMILY SSF63411 4 203 9.95E-51 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TSC_c08010 a03b7dea5a0b4aa27cfb13a4588fca9e 406 Pfam PF00675 Insulinase (Peptidase family M16) 12 158 3.7E-25 T 12-10-2018 IPR011765 Peptidase M16, N-terminal TSC_c11810 b16c0377cc266f05977b02a0cb25970b 64 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 64 2.3E-14 T 12-10-2018 IPR010035 ThiS, thiamine-biosynthesis TSC_c11810 b16c0377cc266f05977b02a0cb25970b 64 Pfam PF02597 ThiS family 5 64 7.3E-12 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TSC_c11810 b16c0377cc266f05977b02a0cb25970b 64 Gene3D G3DSA:3.10.20.30 1 64 1.9E-30 T 12-10-2018 IPR012675 Beta-grasp domain superfamily TSC_c11810 b16c0377cc266f05977b02a0cb25970b 64 SUPERFAMILY SSF54285 2 63 1.6E-15 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TSC_c05940 9d8a8bfd9ab2dac8e94411c2ee090319 606 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 62 108 2.3E-20 T 12-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05940 9d8a8bfd9ab2dac8e94411c2ee090319 606 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 404 426 1.2E-8 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 TSC_c05940 9d8a8bfd9ab2dac8e94411c2ee090319 606 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 344 366 1.2E-8 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 TSC_c05940 9d8a8bfd9ab2dac8e94411c2ee090319 606 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 71 91 1.2E-8 T 12-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 TSC_c05940 9d8a8bfd9ab2dac8e94411c2ee090319 606 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 2 604 5.4E-196 T 12-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05940 9d8a8bfd9ab2dac8e94411c2ee090319 606 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 97 117 3.6E-59 T 12-10-2018 TSC_c05940 9d8a8bfd9ab2dac8e94411c2ee090319 606 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 233 259 3.6E-59 T 12-10-2018 TSC_c05940 9d8a8bfd9ab2dac8e94411c2ee090319 606 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 301 313 3.6E-59 T 12-10-2018 TSC_c05940 9d8a8bfd9ab2dac8e94411c2ee090319 606 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 405 424 3.6E-59 T 12-10-2018 TSC_c05940 9d8a8bfd9ab2dac8e94411c2ee090319 606 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 69 94 3.6E-59 T 12-10-2018 TSC_c05940 9d8a8bfd9ab2dac8e94411c2ee090319 606 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 211 232 3.6E-59 T 12-10-2018 TSC_c05940 9d8a8bfd9ab2dac8e94411c2ee090319 606 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 144 165 3.6E-59 T 12-10-2018 TSC_c05940 9d8a8bfd9ab2dac8e94411c2ee090319 606 Pfam PF00361 Proton-conducting membrane transporter 124 394 1.9E-82 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c09960 b00fca41e11bbd85ca921f36f0b5fd38 100 SUPERFAMILY SSF81301 11 97 1.59E-13 T 12-10-2018 TSC_c09960 b00fca41e11bbd85ca921f36f0b5fd38 100 Pfam PF01909 Nucleotidyltransferase domain 22 56 5.8E-7 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSC_c09960 b00fca41e11bbd85ca921f36f0b5fd38 100 Gene3D G3DSA:3.30.460.10 3 100 5.4E-19 T 12-10-2018 TSC_c19750 fe143614d40ea1f64e32d1368bb9a2a7 182 Gene3D G3DSA:3.40.50.1010 1 147 2.7E-27 T 12-10-2018 TSC_c19750 fe143614d40ea1f64e32d1368bb9a2a7 182 Pfam PF01936 NYN domain 2 144 2.6E-22 T 12-10-2018 IPR021139 NYN domain, limkain-b1-type TSC_c22420 bafdca317dd873e3a57309e067665d0a 96 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 94 21.705 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TSC_c22420 bafdca317dd873e3a57309e067665d0a 96 Gene3D G3DSA:3.30.70.330 1 96 5.2E-37 T 12-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily TSC_c22420 bafdca317dd873e3a57309e067665d0a 96 SUPERFAMILY SSF54189 5 93 3.2E-31 T 12-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22420 bafdca317dd873e3a57309e067665d0a 96 Pfam PF00276 Ribosomal protein L23 6 90 6.1E-31 T 12-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 TSC_c05450 fcfd8c6819ba592948275aaab656a4ff 234 SUPERFAMILY SSF46785 12 82 5.86E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c05450 fcfd8c6819ba592948275aaab656a4ff 234 SMART SM00346 12 98 8.6E-27 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSC_c05450 fcfd8c6819ba592948275aaab656a4ff 234 Pfam PF09339 IclR helix-turn-helix domain 14 62 6.1E-17 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSC_c05450 fcfd8c6819ba592948275aaab656a4ff 234 Gene3D G3DSA:3.30.450.40 80 211 1.1E-43 T 12-10-2018 IPR029016 GAF-like domain superfamily TSC_c05450 fcfd8c6819ba592948275aaab656a4ff 234 Gene3D G3DSA:1.10.10.10 6 79 4.1E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c05450 fcfd8c6819ba592948275aaab656a4ff 234 SUPERFAMILY SSF55781 67 232 1.11E-39 T 12-10-2018 TSC_c05450 fcfd8c6819ba592948275aaab656a4ff 234 Pfam PF01614 Bacterial transcriptional regulator 130 207 3.6E-23 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal TSC_c08360 3b8696707f1b0c9fc1326fce3d3e8af1 465 TIGRFAM TIGR00979 fumC_II: fumarate hydratase, class II 3 458 2.6E-212 T 12-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSC_c08360 3b8696707f1b0c9fc1326fce3d3e8af1 465 ProSitePatterns PS00163 Fumarate lyases signature. 317 326 - T 12-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 TSC_c08360 3b8696707f1b0c9fc1326fce3d3e8af1 465 PRINTS PR00149 Fumarate lyase superfamily signature 271 298 1.2E-31 T 12-10-2018 IPR000362 Fumarate lyase family TSC_c08360 3b8696707f1b0c9fc1326fce3d3e8af1 465 PRINTS PR00149 Fumarate lyase superfamily signature 180 198 1.2E-31 T 12-10-2018 IPR000362 Fumarate lyase family TSC_c08360 3b8696707f1b0c9fc1326fce3d3e8af1 465 PRINTS PR00149 Fumarate lyase superfamily signature 317 333 1.2E-31 T 12-10-2018 IPR000362 Fumarate lyase family TSC_c08360 3b8696707f1b0c9fc1326fce3d3e8af1 465 PRINTS PR00149 Fumarate lyase superfamily signature 134 152 1.2E-31 T 12-10-2018 IPR000362 Fumarate lyase family TSC_c08360 3b8696707f1b0c9fc1326fce3d3e8af1 465 Pfam PF00206 Lyase 11 342 5.9E-111 T 12-10-2018 IPR022761 Fumarate lyase, N-terminal TSC_c08360 3b8696707f1b0c9fc1326fce3d3e8af1 465 SUPERFAMILY SSF48557 3 457 7.23E-156 T 12-10-2018 IPR008948 L-Aspartase-like GO:0003824 TSC_c08360 3b8696707f1b0c9fc1326fce3d3e8af1 465 Pfam PF10415 Fumarase C C-terminus 408 460 1.3E-21 T 12-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSC_c08360 3b8696707f1b0c9fc1326fce3d3e8af1 465 Gene3D G3DSA:1.10.40.30 405 465 8.3E-28 T 12-10-2018 TSC_c08360 3b8696707f1b0c9fc1326fce3d3e8af1 465 Hamap MF_00743 Fumarate hydratase class II [fumC]. 3 462 90.004 T 12-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSC_c08360 3b8696707f1b0c9fc1326fce3d3e8af1 465 Gene3D G3DSA:1.20.200.10 139 404 4.9E-115 T 12-10-2018 TSC_c08360 3b8696707f1b0c9fc1326fce3d3e8af1 465 Gene3D G3DSA:1.10.275.10 1 138 3.6E-64 T 12-10-2018 IPR024083 Fumarase/histidase, N-terminal TSC_c00220 685e1a089d2cc1d1ca8bfbd1d48e7637 356 Pfam PF13186 Iron-sulfur cluster-binding domain 261 316 9.8E-5 T 12-10-2018 IPR023885 4Fe4S-binding SPASM domain TSC_c00220 685e1a089d2cc1d1ca8bfbd1d48e7637 356 TIGRFAM TIGR04053 sam_11: radical SAM protein, BA_1875 family 4 347 1.0E-136 T 12-10-2018 IPR027634 Radical SAM protein, BA_1875 family TSC_c00220 685e1a089d2cc1d1ca8bfbd1d48e7637 356 Pfam PF04055 Radical SAM superfamily 15 155 1.6E-16 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSC_c00220 685e1a089d2cc1d1ca8bfbd1d48e7637 356 PIRSF PIRSF037420 2 353 5.7E-88 T 12-10-2018 IPR017200 Coenzyme PQQ synthesis protein E TSC_c00220 685e1a089d2cc1d1ca8bfbd1d48e7637 356 Gene3D G3DSA:3.20.20.70 9 298 4.6E-38 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c00220 685e1a089d2cc1d1ca8bfbd1d48e7637 356 SMART SM00729 10 213 0.0023 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSC_c00220 685e1a089d2cc1d1ca8bfbd1d48e7637 356 SUPERFAMILY SSF102114 4 324 3.4E-61 T 12-10-2018 TSC_c02100 038274cf464a8a1caaf23a93d211bfb0 96 Gene3D G3DSA:1.10.287.1080 1 95 5.1E-26 T 12-10-2018 TSC_c02100 038274cf464a8a1caaf23a93d211bfb0 96 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 15 91 1.3E-16 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TSC_c02100 038274cf464a8a1caaf23a93d211bfb0 96 PIRSF PIRSF029904 1 96 9.7E-39 T 12-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD TSC_c02100 038274cf464a8a1caaf23a93d211bfb0 96 SUPERFAMILY SSF101386 2 91 1.21E-21 T 12-10-2018 TSC_c10480 bfa423751df34006bc75dc22cc0e3fc6 390 Pfam PF13458 Periplasmic binding protein 21 381 3.5E-55 T 12-10-2018 IPR028081 Leucine-binding protein domain TSC_c10480 bfa423751df34006bc75dc22cc0e3fc6 390 Gene3D G3DSA:3.40.50.2300 145 382 2.7E-111 T 12-10-2018 TSC_c10480 bfa423751df34006bc75dc22cc0e3fc6 390 SUPERFAMILY SSF53822 21 385 3.53E-79 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TSC_c10480 bfa423751df34006bc75dc22cc0e3fc6 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 62 80 2.3E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSC_c10480 bfa423751df34006bc75dc22cc0e3fc6 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 83 93 2.3E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSC_c10480 bfa423751df34006bc75dc22cc0e3fc6 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 250 268 2.3E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSC_c10480 bfa423751df34006bc75dc22cc0e3fc6 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 21 37 2.3E-5 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSC_c10480 bfa423751df34006bc75dc22cc0e3fc6 390 Gene3D G3DSA:3.40.50.2300 23 368 2.7E-111 T 12-10-2018 TSC_c21330 3baf95267fb5b6712ee5a4c5f23fd84f 194 Gene3D G3DSA:3.40.1360.10 75 194 1.8E-40 T 12-10-2018 TSC_c21330 3baf95267fb5b6712ee5a4c5f23fd84f 194 TIGRFAM TIGR00615 recR: recombination protein RecR 2 192 4.2E-64 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 TSC_c21330 3baf95267fb5b6712ee5a4c5f23fd84f 194 Hamap MF_00017 Recombination protein RecR [recR]. 1 194 86.771 T 12-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 TSC_c21330 3baf95267fb5b6712ee5a4c5f23fd84f 194 Pfam PF02132 RecR protein 39 76 9.1E-11 T 12-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger TSC_c21330 3baf95267fb5b6712ee5a4c5f23fd84f 194 SMART SM00493 78 161 1.0E-10 T 12-10-2018 IPR006171 TOPRIM domain TSC_c21330 3baf95267fb5b6712ee5a4c5f23fd84f 194 Gene3D G3DSA:1.10.8.420 1 50 6.8E-15 T 12-10-2018 TSC_c21330 3baf95267fb5b6712ee5a4c5f23fd84f 194 Pfam PF13662 Toprim domain 78 167 2.0E-22 T 12-10-2018 IPR006171 TOPRIM domain TSC_c21330 3baf95267fb5b6712ee5a4c5f23fd84f 194 ProSitePatterns PS01300 RecR protein signature. 55 76 - T 12-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 TSC_c21330 3baf95267fb5b6712ee5a4c5f23fd84f 194 SUPERFAMILY SSF111304 1 194 1.96E-66 T 12-10-2018 IPR023627 Recombination protein RecR TSC_c14560 a7da6fdf7a0777e6cbc390e8a9f59017 351 SMART SM00865 199 317 2.6E-39 T 12-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 TSC_c14560 a7da6fdf7a0777e6cbc390e8a9f59017 351 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 3 313 3.7E-120 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TSC_c14560 a7da6fdf7a0777e6cbc390e8a9f59017 351 SUPERFAMILY SSF55307 196 313 2.75E-35 T 12-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 TSC_c14560 a7da6fdf7a0777e6cbc390e8a9f59017 351 Pfam PF12327 FtsZ family, C-terminal domain 214 308 3.6E-23 T 12-10-2018 IPR024757 Cell division protein FtsZ, C-terminal TSC_c14560 a7da6fdf7a0777e6cbc390e8a9f59017 351 SUPERFAMILY SSF52490 6 197 4.84E-68 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TSC_c14560 a7da6fdf7a0777e6cbc390e8a9f59017 351 PRINTS PR00423 Cell division protein FtsZ signature 90 110 2.0E-47 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSC_c14560 a7da6fdf7a0777e6cbc390e8a9f59017 351 PRINTS PR00423 Cell division protein FtsZ signature 204 225 2.0E-47 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSC_c14560 a7da6fdf7a0777e6cbc390e8a9f59017 351 PRINTS PR00423 Cell division protein FtsZ signature 181 203 2.0E-47 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSC_c14560 a7da6fdf7a0777e6cbc390e8a9f59017 351 PRINTS PR00423 Cell division protein FtsZ signature 118 139 2.0E-47 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSC_c14560 a7da6fdf7a0777e6cbc390e8a9f59017 351 SMART SM00864 5 197 4.5E-111 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSC_c14560 a7da6fdf7a0777e6cbc390e8a9f59017 351 ProSitePatterns PS01134 FtsZ protein signature 1. 36 70 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TSC_c14560 a7da6fdf7a0777e6cbc390e8a9f59017 351 Gene3D G3DSA:3.40.50.1440 3 309 1.1E-111 T 12-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 TSC_c14560 a7da6fdf7a0777e6cbc390e8a9f59017 351 ProSitePatterns PS01135 FtsZ protein signature 2. 89 110 - T 12-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 TSC_c14560 a7da6fdf7a0777e6cbc390e8a9f59017 351 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 6 164 5.2E-42 T 12-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 TSC_c14560 a7da6fdf7a0777e6cbc390e8a9f59017 351 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 1 341 37.269 T 12-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 TSC_c09910 bce4ca851cef43e9eb6bfcb091ab3efa 379 Gene3D G3DSA:3.40.50.2000 27 368 8.7E-82 T 12-10-2018 TSC_c09910 bce4ca851cef43e9eb6bfcb091ab3efa 379 SUPERFAMILY SSF53756 22 376 2.34E-82 T 12-10-2018 TSC_c09910 bce4ca851cef43e9eb6bfcb091ab3efa 379 Pfam PF13439 Glycosyltransferase Family 4 27 186 1.2E-28 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSC_c09910 bce4ca851cef43e9eb6bfcb091ab3efa 379 Gene3D G3DSA:3.40.50.2000 182 358 8.7E-82 T 12-10-2018 TSC_c09910 bce4ca851cef43e9eb6bfcb091ab3efa 379 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 17 375 2.3E-102 T 12-10-2018 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 TSC_c09910 bce4ca851cef43e9eb6bfcb091ab3efa 379 Pfam PF00534 Glycosyl transferases group 1 192 353 8.5E-28 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TSC_c00820 08d99cb86e37278a07b437cd8f3b5801 101 SUPERFAMILY SSF50129 8 100 2.47E-35 T 12-10-2018 IPR011032 GroES-like superfamily TSC_c00820 08d99cb86e37278a07b437cd8f3b5801 101 Pfam PF00166 Chaperonin 10 Kd subunit 9 99 9.3E-37 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSC_c00820 08d99cb86e37278a07b437cd8f3b5801 101 SMART SM00883 8 100 1.4E-54 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSC_c00820 08d99cb86e37278a07b437cd8f3b5801 101 Hamap MF_00580 10 kDa chaperonin [groS]. 8 101 28.033 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSC_c00820 08d99cb86e37278a07b437cd8f3b5801 101 ProSitePatterns PS00681 Chaperonins cpn10 signature. 9 33 - T 12-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 TSC_c00820 08d99cb86e37278a07b437cd8f3b5801 101 Gene3D G3DSA:2.30.33.40 8 101 1.4E-39 T 12-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 TSC_c00820 08d99cb86e37278a07b437cd8f3b5801 101 PRINTS PR00297 10kDa chaperonin signature 87 100 4.4E-33 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSC_c00820 08d99cb86e37278a07b437cd8f3b5801 101 PRINTS PR00297 10kDa chaperonin signature 9 24 4.4E-33 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSC_c00820 08d99cb86e37278a07b437cd8f3b5801 101 PRINTS PR00297 10kDa chaperonin signature 31 52 4.4E-33 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSC_c00820 08d99cb86e37278a07b437cd8f3b5801 101 PRINTS PR00297 10kDa chaperonin signature 66 78 4.4E-33 T 12-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 TSC_c15220 7829e6fbce0b6e386dfa79e1c6541941 386 SUPERFAMILY SSF56024 58 219 4.19E-27 T 12-10-2018 TSC_c15220 7829e6fbce0b6e386dfa79e1c6541941 386 Gene3D G3DSA:3.30.870.10 239 385 5.1E-36 T 12-10-2018 TSC_c15220 7829e6fbce0b6e386dfa79e1c6541941 386 SMART SM00155 163 190 6.7E-5 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 TSC_c15220 7829e6fbce0b6e386dfa79e1c6541941 386 SMART SM00155 325 352 2.1E-5 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 TSC_c15220 7829e6fbce0b6e386dfa79e1c6541941 386 Pfam PF13091 PLD-like domain 67 216 2.7E-19 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 TSC_c15220 7829e6fbce0b6e386dfa79e1c6541941 386 Pfam PF13091 PLD-like domain 259 380 1.0E-25 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 TSC_c15220 7829e6fbce0b6e386dfa79e1c6541941 386 SUPERFAMILY SSF56024 255 385 2.69E-31 T 12-10-2018 TSC_c15220 7829e6fbce0b6e386dfa79e1c6541941 386 Gene3D G3DSA:3.30.870.10 45 225 1.0E-36 T 12-10-2018 TSC_c14760 99a2f268e66f51879ded88fd5a6f55d1 250 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c14760 99a2f268e66f51879ded88fd5a6f55d1 250 Pfam PF00005 ABC transporter 17 163 1.7E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c14760 99a2f268e66f51879ded88fd5a6f55d1 250 SUPERFAMILY SSF52540 13 223 1.03E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c14760 99a2f268e66f51879ded88fd5a6f55d1 250 Gene3D G3DSA:3.40.50.300 9 241 1.7E-58 T 12-10-2018 TSC_c14760 99a2f268e66f51879ded88fd5a6f55d1 250 SMART SM00382 24 211 1.7E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c08350 5b87154230b9dbf66d1f82196115131a 204 PRINTS PR01703 Manganese superoxide dismutase signature 8 19 2.8E-26 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSC_c08350 5b87154230b9dbf66d1f82196115131a 204 PRINTS PR01703 Manganese superoxide dismutase signature 165 177 2.8E-26 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSC_c08350 5b87154230b9dbf66d1f82196115131a 204 PRINTS PR01703 Manganese superoxide dismutase signature 128 136 2.8E-26 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSC_c08350 5b87154230b9dbf66d1f82196115131a 204 PRINTS PR01703 Manganese superoxide dismutase signature 29 42 2.8E-26 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSC_c08350 5b87154230b9dbf66d1f82196115131a 204 PRINTS PR01703 Manganese superoxide dismutase signature 75 88 2.8E-26 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSC_c08350 5b87154230b9dbf66d1f82196115131a 204 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 5 91 1.3E-30 T 12-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSC_c08350 5b87154230b9dbf66d1f82196115131a 204 SUPERFAMILY SSF54719 92 202 4.06E-43 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSC_c08350 5b87154230b9dbf66d1f82196115131a 204 Gene3D G3DSA:2.40.500.20 93 204 1.2E-47 T 12-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSC_c08350 5b87154230b9dbf66d1f82196115131a 204 SUPERFAMILY SSF46609 3 93 1.83E-34 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSC_c08350 5b87154230b9dbf66d1f82196115131a 204 Gene3D G3DSA:1.10.287.990 22 92 2.4E-32 T 12-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSC_c08350 5b87154230b9dbf66d1f82196115131a 204 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 99 198 1.1E-38 T 12-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSC_c08350 5b87154230b9dbf66d1f82196115131a 204 PIRSF PIRSF000349 1 204 1.4E-77 T 12-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSC_c08350 5b87154230b9dbf66d1f82196115131a 204 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 167 174 - T 12-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 TSC_c18730 4019662f57a8ce5de21f4b2f09529632 211 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 116 201 1.4E-14 T 12-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 TSC_c18730 4019662f57a8ce5de21f4b2f09529632 211 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 54 105 3.0E-21 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TSC_c18730 4019662f57a8ce5de21f4b2f09529632 211 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 4 203 35.782 T 12-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 TSC_c18730 4019662f57a8ce5de21f4b2f09529632 211 SUPERFAMILY SSF101386 114 203 4.49E-24 T 12-10-2018 TSC_c18730 4019662f57a8ce5de21f4b2f09529632 211 Gene3D G3DSA:3.10.20.400 1 92 5.4E-39 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 TSC_c18730 4019662f57a8ce5de21f4b2f09529632 211 SUPERFAMILY SSF141734 3 107 2.22E-45 T 12-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 TSC_c18730 4019662f57a8ce5de21f4b2f09529632 211 Gene3D G3DSA:1.10.287.1080 112 203 8.4E-29 T 12-10-2018 TSC_c18730 4019662f57a8ce5de21f4b2f09529632 211 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 112 198 20.423 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 TSC_c18730 4019662f57a8ce5de21f4b2f09529632 211 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 29 101 2.2E-32 T 12-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TSC_c18730 4019662f57a8ce5de21f4b2f09529632 211 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 2 105 30.216 T 12-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 TSC_c18730 4019662f57a8ce5de21f4b2f09529632 211 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 115 198 6.7E-29 T 12-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 TSC_c07210 c7790cecd2250e6cc88ead4224fd8a91 344 Gene3D G3DSA:3.20.20.70 77 332 1.6E-95 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c07210 c7790cecd2250e6cc88ead4224fd8a91 344 Gene3D G3DSA:3.30.70.1140 1 76 4.9E-21 T 12-10-2018 TSC_c07210 c7790cecd2250e6cc88ead4224fd8a91 344 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 72 328 1.2E-115 T 12-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 TSC_c07210 c7790cecd2250e6cc88ead4224fd8a91 344 Pfam PF00793 DAHP synthetase I family 92 323 8.0E-73 T 12-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 TSC_c07210 c7790cecd2250e6cc88ead4224fd8a91 344 SUPERFAMILY SSF51569 1 336 1.65E-108 T 12-10-2018 TSC_c23430 7e6f2a2766a99308632263a7ef049853 136 SUPERFAMILY SSF160443 59 135 1.44E-11 T 12-10-2018 IPR036063 Smr domain superfamily TSC_c23430 7e6f2a2766a99308632263a7ef049853 136 Gene3D G3DSA:3.30.1370.110 51 135 1.3E-24 T 12-10-2018 TSC_c23430 7e6f2a2766a99308632263a7ef049853 136 Pfam PF01713 Smr domain 60 135 5.3E-20 T 12-10-2018 IPR002625 Smr domain TSC_c23430 7e6f2a2766a99308632263a7ef049853 136 SMART SM00463 57 135 2.1E-18 T 12-10-2018 IPR002625 Smr domain TSC_c05250 8180d65ea85ea4f5be0a02fdec74f7c0 327 Pfam PF16868 NMT1-like family 25 324 1.7E-64 T 12-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TSC_c05250 8180d65ea85ea4f5be0a02fdec74f7c0 327 SUPERFAMILY SSF53850 22 326 7.03E-56 T 12-10-2018 TSC_c05250 8180d65ea85ea4f5be0a02fdec74f7c0 327 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 324 1.5E-76 T 12-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TSC_c05250 8180d65ea85ea4f5be0a02fdec74f7c0 327 Gene3D G3DSA:3.40.190.10 113 258 3.4E-88 T 12-10-2018 TSC_c05250 8180d65ea85ea4f5be0a02fdec74f7c0 327 Gene3D G3DSA:3.40.190.10 25 324 3.4E-88 T 12-10-2018 TSC_c14030 67fc1cf8b49a7f76ed038fd9dbb43f57 507 SUPERFAMILY SSF54675 5 153 4.12E-34 T 12-10-2018 TSC_c14030 67fc1cf8b49a7f76ed038fd9dbb43f57 507 PIRSF PIRSF000484 1 506 3.0E-142 T 12-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 TSC_c14030 67fc1cf8b49a7f76ed038fd9dbb43f57 507 Gene3D G3DSA:3.20.20.70 160 346 2.8E-163 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c14030 67fc1cf8b49a7f76ed038fd9dbb43f57 507 Gene3D G3DSA:3.20.140.10 7 497 2.8E-163 T 12-10-2018 TSC_c14030 67fc1cf8b49a7f76ed038fd9dbb43f57 507 SUPERFAMILY SSF51690 148 503 4.37E-97 T 12-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 TSC_c14030 67fc1cf8b49a7f76ed038fd9dbb43f57 507 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 7 493 3.7E-129 T 12-10-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 TSC_c05720 4a2aef2d0d76266ee95e10fd8a4f0162 253 Pfam PF00005 ABC transporter 19 180 1.9E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c05720 4a2aef2d0d76266ee95e10fd8a4f0162 253 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 228 250 5.9E-11 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSC_c05720 4a2aef2d0d76266ee95e10fd8a4f0162 253 SMART SM00382 28 227 7.4E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c05720 4a2aef2d0d76266ee95e10fd8a4f0162 253 SUPERFAMILY SSF52540 4 249 1.41E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c05720 4a2aef2d0d76266ee95e10fd8a4f0162 253 Gene3D G3DSA:3.40.50.300 2 251 4.2E-64 T 12-10-2018 TSC_c18030 dd38e948f04953c6451d769a2d3b5e1a 308 Gene3D G3DSA:3.30.70.260 218 305 1.2E-29 T 12-10-2018 TSC_c18030 dd38e948f04953c6451d769a2d3b5e1a 308 SUPERFAMILY SSF53850 36 216 3.69E-62 T 12-10-2018 TSC_c18030 dd38e948f04953c6451d769a2d3b5e1a 308 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 251 258 - T 12-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 TSC_c18030 dd38e948f04953c6451d769a2d3b5e1a 308 Pfam PF01842 ACT domain 225 285 4.3E-8 T 12-10-2018 IPR002912 ACT domain TSC_c18030 dd38e948f04953c6451d769a2d3b5e1a 308 SUPERFAMILY SSF55021 207 303 1.16E-25 T 12-10-2018 TSC_c18030 dd38e948f04953c6451d769a2d3b5e1a 308 PIRSF PIRSF001500 25 305 5.3E-83 T 12-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 TSC_c18030 dd38e948f04953c6451d769a2d3b5e1a 308 Gene3D G3DSA:3.40.190.10 120 200 2.5E-29 T 12-10-2018 TSC_c18030 dd38e948f04953c6451d769a2d3b5e1a 308 Pfam PF00800 Prephenate dehydratase 38 214 5.6E-63 T 12-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 TSC_c18030 dd38e948f04953c6451d769a2d3b5e1a 308 Gene3D G3DSA:3.40.190.10 31 119 3.5E-30 T 12-10-2018 TSC_c13450 95ff2f2e7ab8b273130e971a5de7261c 380 Pfam PF00561 alpha/beta hydrolase fold 70 366 2.1E-25 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSC_c13450 95ff2f2e7ab8b273130e971a5de7261c 380 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 41 379 6.1E-122 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 TSC_c13450 95ff2f2e7ab8b273130e971a5de7261c 380 PRINTS PR00111 Alpha/beta hydrolase fold signature 182 195 1.3E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSC_c13450 95ff2f2e7ab8b273130e971a5de7261c 380 PRINTS PR00111 Alpha/beta hydrolase fold signature 196 209 1.3E-6 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSC_c13450 95ff2f2e7ab8b273130e971a5de7261c 380 Hamap MF_00296 Homoserine O-acetyltransferase [metXA]. 29 380 31.058 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 TSC_c13450 95ff2f2e7ab8b273130e971a5de7261c 380 SUPERFAMILY SSF53474 36 379 2.94E-87 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c13450 95ff2f2e7ab8b273130e971a5de7261c 380 Gene3D G3DSA:3.40.50.1820 39 380 2.8E-120 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c13450 95ff2f2e7ab8b273130e971a5de7261c 380 PIRSF PIRSF000443 30 380 2.9E-108 T 12-10-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 TSC_c09060 c3473f6210b785bbd603a7c952aebbd5 391 SUPERFAMILY SSF53822 21 350 2.29E-68 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TSC_c09060 c3473f6210b785bbd603a7c952aebbd5 391 Gene3D G3DSA:3.40.50.2300 27 342 8.0E-69 T 12-10-2018 TSC_c09060 c3473f6210b785bbd603a7c952aebbd5 391 Gene3D G3DSA:3.40.50.2300 139 268 8.0E-69 T 12-10-2018 TSC_c09060 c3473f6210b785bbd603a7c952aebbd5 391 Pfam PF13458 Periplasmic binding protein 21 345 1.8E-59 T 12-10-2018 IPR028081 Leucine-binding protein domain TSC_c22340 d1c371786a8947fb64772978a7192f60 122 SMART SM01374 1 122 2.8E-88 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TSC_c22340 d1c371786a8947fb64772978a7192f60 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.823 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TSC_c22340 d1c371786a8947fb64772978a7192f60 122 SUPERFAMILY SSF50193 1 122 3.92E-53 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TSC_c22340 d1c371786a8947fb64772978a7192f60 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 12-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22340 d1c371786a8947fb64772978a7192f60 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 6.4E-57 T 12-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 TSC_c22340 d1c371786a8947fb64772978a7192f60 122 Gene3D G3DSA:2.40.150.20 1 122 3.9E-57 T 12-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 TSC_c22340 d1c371786a8947fb64772978a7192f60 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 2.0E-58 T 12-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 TSC_c09110 275f15901d4d362e50aa57955fa607b5 335 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 241 328 7.2E-17 T 12-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TSC_c09110 275f15901d4d362e50aa57955fa607b5 335 Gene3D G3DSA:3.40.47.10 1 173 1.1E-29 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c09110 275f15901d4d362e50aa57955fa607b5 335 SUPERFAMILY SSF53901 6 329 4.61E-26 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c09110 275f15901d4d362e50aa57955fa607b5 335 Gene3D G3DSA:3.40.47.10 175 329 1.3E-30 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c09110 275f15901d4d362e50aa57955fa607b5 335 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 105 182 1.1E-9 T 12-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 TSC_c21960 00230543b9a8b7067534f3621c515a62 365 Pfam PF08486 Stage II sporulation protein 99 186 2.2E-25 T 12-10-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal TSC_c21960 00230543b9a8b7067534f3621c515a62 365 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 103 348 1.2E-71 T 12-10-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 TSC_c21960 00230543b9a8b7067534f3621c515a62 365 ProDom PD191273 TC0311 EXPORTED CT041 CPN0389/CP0366/CPJ0389/CPB0400 83 184 2.0E-5 T 12-10-2018 TSC_c02560 76817c882e1c9bf05c5daf2a9d14d68f 219 Pfam PF00072 Response regulator receiver domain 3 115 7.5E-21 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c02560 76817c882e1c9bf05c5daf2a9d14d68f 219 SUPERFAMILY SSF52172 2 176 3.56E-34 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c02560 76817c882e1c9bf05c5daf2a9d14d68f 219 SMART SM00862 147 215 6.5E-20 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c02560 76817c882e1c9bf05c5daf2a9d14d68f 219 Gene3D G3DSA:1.10.10.10 121 218 5.2E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c02560 76817c882e1c9bf05c5daf2a9d14d68f 219 SMART SM00448 1 114 1.9E-33 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c02560 76817c882e1c9bf05c5daf2a9d14d68f 219 Gene3D G3DSA:3.40.50.2300 1 120 1.8E-33 T 12-10-2018 TSC_c02560 76817c882e1c9bf05c5daf2a9d14d68f 219 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 215 2.4E-15 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c11210 87d653b1e5213f751ad810eadcc6e708 437 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 173 427 3.4E-71 T 12-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TSC_c11210 87d653b1e5213f751ad810eadcc6e708 437 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 2 170 6.7E-40 T 12-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TSC_c11210 87d653b1e5213f751ad810eadcc6e708 437 PIRSF PIRSF000110 1 436 2.4E-115 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TSC_c11210 87d653b1e5213f751ad810eadcc6e708 437 SUPERFAMILY SSF55347 160 431 8.17E-78 T 12-10-2018 TSC_c11210 87d653b1e5213f751ad810eadcc6e708 437 Gene3D G3DSA:3.40.50.720 1 385 7.8E-126 T 12-10-2018 TSC_c11210 87d653b1e5213f751ad810eadcc6e708 437 SUPERFAMILY SSF51735 1 172 3.35E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c11210 87d653b1e5213f751ad810eadcc6e708 437 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 1 434 73.573 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TSC_c11210 87d653b1e5213f751ad810eadcc6e708 437 Gene3D G3DSA:3.30.360.10 160 420 7.8E-126 T 12-10-2018 TSC_c11210 87d653b1e5213f751ad810eadcc6e708 437 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 150 178 5.2E-42 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TSC_c11210 87d653b1e5213f751ad810eadcc6e708 437 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 126 139 5.2E-42 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TSC_c11210 87d653b1e5213f751ad810eadcc6e708 437 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 202 219 5.2E-42 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TSC_c11210 87d653b1e5213f751ad810eadcc6e708 437 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 297 323 5.2E-42 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TSC_c11210 87d653b1e5213f751ad810eadcc6e708 437 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 220 236 5.2E-42 T 12-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 TSC_c13420 be13185fa4e6ee40c8482651757a123e 496 Pfam PF01895 PhoU domain 308 388 1.7E-5 T 12-10-2018 IPR026022 PhoU domain TSC_c13420 be13185fa4e6ee40c8482651757a123e 496 SUPERFAMILY SSF109755 290 493 6.91E-22 T 12-10-2018 TSC_c13420 be13185fa4e6ee40c8482651757a123e 496 Gene3D G3DSA:1.20.58.220 303 393 1.1E-5 T 12-10-2018 IPR038078 PhoU-like domain superfamily TSC_c13420 be13185fa4e6ee40c8482651757a123e 496 Gene3D G3DSA:1.20.58.220 402 496 8.9E-6 T 12-10-2018 IPR038078 PhoU-like domain superfamily TSC_c13420 be13185fa4e6ee40c8482651757a123e 496 Pfam PF02690 Na+/Pi-cotransporter 9 138 4.4E-10 T 12-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 TSC_c20080 1df2f64b64e765dcd40712041302a7aa 578 SUPERFAMILY SSF55729 96 297 3.54E-11 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSC_c20080 1df2f64b64e765dcd40712041302a7aa 578 Pfam PF00005 ABC transporter 390 515 1.3E-17 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c20080 1df2f64b64e765dcd40712041302a7aa 578 SUPERFAMILY SSF52540 386 561 9.94E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c20080 1df2f64b64e765dcd40712041302a7aa 578 Gene3D G3DSA:3.40.50.300 366 575 3.0E-38 T 12-10-2018 TSC_c20080 1df2f64b64e765dcd40712041302a7aa 578 Pfam PF00583 Acetyltransferase (GNAT) family 167 291 4.3E-7 T 12-10-2018 IPR000182 GNAT domain TSC_c20080 1df2f64b64e765dcd40712041302a7aa 578 SMART SM00382 398 575 5.0E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c02430 78bba0656456198f79db3dd2c6c9f7ec 301 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 74 283 4.2E-45 T 12-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSC_c02430 78bba0656456198f79db3dd2c6c9f7ec 301 Gene3D G3DSA:1.10.10.10 1 54 6.0E-11 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c02430 78bba0656456198f79db3dd2c6c9f7ec 301 SUPERFAMILY SSF46785 4 53 1.59E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c02430 78bba0656456198f79db3dd2c6c9f7ec 301 Gene3D G3DSA:3.30.930.10 59 249 1.5E-43 T 12-10-2018 TSC_c02430 78bba0656456198f79db3dd2c6c9f7ec 301 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 3 291 27.601 T 12-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 TSC_c02430 78bba0656456198f79db3dd2c6c9f7ec 301 SUPERFAMILY SSF55681 64 243 5.22E-41 T 12-10-2018 TSC_c02430 78bba0656456198f79db3dd2c6c9f7ec 301 Gene3D G3DSA:2.30.30.100 250 290 3.3E-5 T 12-10-2018 TSC_c02430 78bba0656456198f79db3dd2c6c9f7ec 301 Pfam PF08279 HTH domain 5 51 1.7E-9 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 TSC_c02430 78bba0656456198f79db3dd2c6c9f7ec 301 Pfam PF03099 Biotin/lipoate A/B protein ligase family 78 196 2.0E-10 T 12-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 TSC_c21910 db8f5540e18a252aa7c3f377173fc999 396 Gene3D G3DSA:3.40.50.10300 183 395 3.5E-76 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TSC_c21910 db8f5540e18a252aa7c3f377173fc999 396 Pfam PF02441 Flavoprotein 3 175 3.6E-41 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TSC_c21910 db8f5540e18a252aa7c3f377173fc999 396 SUPERFAMILY SSF52507 3 177 1.18E-49 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TSC_c21910 db8f5540e18a252aa7c3f377173fc999 396 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 183 365 4.9E-65 T 12-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TSC_c21910 db8f5540e18a252aa7c3f377173fc999 396 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 3 390 2.6E-113 T 12-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 TSC_c21910 db8f5540e18a252aa7c3f377173fc999 396 SUPERFAMILY SSF102645 181 395 6.15E-72 T 12-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 TSC_c21910 db8f5540e18a252aa7c3f377173fc999 396 Gene3D G3DSA:3.40.50.1950 2 182 9.5E-48 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TSC_c11320 bf8c2487f71a24045fb1414cb3f21ee5 418 Pfam PF00005 ABC transporter 24 161 4.4E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c11320 bf8c2487f71a24045fb1414cb3f21ee5 418 Pfam PF09821 C-terminal AAA-associated domain 290 404 3.5E-35 T 12-10-2018 IPR018632 C-terminal AAA-associated domain TSC_c11320 bf8c2487f71a24045fb1414cb3f21ee5 418 Gene3D G3DSA:3.40.50.300 1 274 3.4E-58 T 12-10-2018 TSC_c11320 bf8c2487f71a24045fb1414cb3f21ee5 418 SUPERFAMILY SSF52540 3 242 1.03E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c11320 bf8c2487f71a24045fb1414cb3f21ee5 418 SMART SM00382 31 227 7.7E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c11320 bf8c2487f71a24045fb1414cb3f21ee5 418 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 200 308 4.8E-26 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 SUPERFAMILY SSF48452 557 709 6.01E-25 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 Gene3D G3DSA:1.25.40.10 521 718 5.9E-32 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 Pfam PF14559 Tetratricopeptide repeat 662 717 3.0E-6 T 12-10-2018 TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 Pfam PF00512 His Kinase A (phospho-acceptor) domain 91 155 4.7E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 Pfam PF13432 Tetratricopeptide repeat 557 604 4.5E-4 T 12-10-2018 TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 SUPERFAMILY SSF47384 76 154 3.73E-10 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 PRINTS PR00344 Bacterial sensor protein C-terminal signature 270 288 5.3E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 PRINTS PR00344 Bacterial sensor protein C-terminal signature 255 265 5.3E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 PRINTS PR00344 Bacterial sensor protein C-terminal signature 237 251 5.3E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 PRINTS PR00344 Bacterial sensor protein C-terminal signature 294 307 5.3E-20 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 SMART SM00387 200 310 9.1E-41 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 SMART SM00388 89 155 1.2E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 SMART SM00028 643 676 90.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 SMART SM00028 677 710 18.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 SMART SM00028 611 642 390.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 SMART SM00028 576 609 0.0068 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 Gene3D G3DSA:3.30.565.10 153 307 1.2E-56 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 SUPERFAMILY SSF55874 156 309 3.8E-46 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c19930 e1b85a85a8bed9d26d8de4f7dd5df54e 723 Gene3D G3DSA:1.10.287.130 97 152 1.2E-56 T 12-10-2018 TSC_c21840 199124f46d884c426d2c780edc51847f 463 SUPERFAMILY SSF53271 245 452 2.36E-67 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TSC_c21840 199124f46d884c426d2c780edc51847f 463 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 8 448 6.4E-154 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TSC_c21840 199124f46d884c426d2c780edc51847f 463 Pfam PF00156 Phosphoribosyl transferase domain 275 382 1.1E-10 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSC_c21840 199124f46d884c426d2c780edc51847f 463 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 7 447 44.665 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TSC_c21840 199124f46d884c426d2c780edc51847f 463 Gene3D G3DSA:3.40.50.2020 270 433 1.0E-148 T 12-10-2018 TSC_c21840 199124f46d884c426d2c780edc51847f 463 SUPERFAMILY SSF56235 8 252 7.38E-61 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSC_c21840 199124f46d884c426d2c780edc51847f 463 Gene3D G3DSA:3.60.20.10 8 448 1.0E-148 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSC_c21840 199124f46d884c426d2c780edc51847f 463 Pfam PF13537 Glutamine amidotransferase domain 91 210 1.2E-22 T 12-10-2018 IPR017932 Glutamine amidotransferase type 2 domain TSC_c21840 199124f46d884c426d2c780edc51847f 463 PIRSF PIRSF000485 4 462 2.1E-162 T 12-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 TSC_c24380 50dc54acf4b448ea07501edc948261cf 323 SUPERFAMILY SSF52540 50 190 2.72E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c24380 50dc54acf4b448ea07501edc948261cf 323 Pfam PF03969 AFG1-like ATPase 13 205 9.9E-29 T 12-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 TSC_c24380 50dc54acf4b448ea07501edc948261cf 323 Pfam PF03969 AFG1-like ATPase 227 321 1.4E-10 T 12-10-2018 IPR005654 ATPase, AFG1-like GO:0005524 TSC_c24380 50dc54acf4b448ea07501edc948261cf 323 Gene3D G3DSA:3.40.50.300 10 193 8.4E-15 T 12-10-2018 TSC_c11630 fa6ddb274643d60ff03a9abfc245a676 281 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 3 250 2.1E-59 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TSC_c11630 fa6ddb274643d60ff03a9abfc245a676 281 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 281 69.237 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TSC_c11630 fa6ddb274643d60ff03a9abfc245a676 281 Pfam PF03186 CobD/Cbib protein 3 252 3.0E-77 T 12-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 TSC_c02170 159b663454f0bad554754c569d4d9385 296 SUPERFAMILY SSF103481 51 145 1.24E-14 T 12-10-2018 TSC_c02170 159b663454f0bad554754c569d4d9385 296 SUPERFAMILY SSF103481 196 292 2.62E-9 T 12-10-2018 TSC_c02170 159b663454f0bad554754c569d4d9385 296 Pfam PF00892 EamA-like transporter family 11 140 2.3E-10 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSC_c02170 159b663454f0bad554754c569d4d9385 296 Pfam PF00892 EamA-like transporter family 156 288 1.1E-13 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSC_c25020 757adcc670c5885e555cc5f7dc408cdf 687 SUPERFAMILY SSF56281 453 683 4.06E-34 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c25020 757adcc670c5885e555cc5f7dc408cdf 687 Pfam PF13567 Domain of unknown function (DUF4131) 108 148 3.0E-8 T 12-10-2018 IPR025405 Domain of unknown function DUF4131 TSC_c25020 757adcc670c5885e555cc5f7dc408cdf 687 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 199 365 3.6E-20 T 12-10-2018 IPR004477 ComEC/Rec2-related protein TSC_c25020 757adcc670c5885e555cc5f7dc408cdf 687 Gene3D G3DSA:3.60.15.10 456 685 8.9E-52 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c25020 757adcc670c5885e555cc5f7dc408cdf 687 SMART SM00849 464 649 0.0094 T 12-10-2018 IPR001279 Metallo-beta-lactamase TSC_c25020 757adcc670c5885e555cc5f7dc408cdf 687 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 117 677 4.7E-59 T 12-10-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 TSC_c25020 757adcc670c5885e555cc5f7dc408cdf 687 Pfam PF03772 Competence protein 179 426 2.9E-42 T 12-10-2018 IPR004477 ComEC/Rec2-related protein TSC_c25020 757adcc670c5885e555cc5f7dc408cdf 687 Pfam PF00753 Metallo-beta-lactamase superfamily 462 645 1.4E-7 T 12-10-2018 IPR001279 Metallo-beta-lactamase TSC_c21100 6c4526d7126b05cfa72d46bc219c70de 108 Pfam PF08770 Sulphur oxidation protein SoxZ 14 103 4.6E-26 T 12-10-2018 IPR014880 Sulphur oxidation protein SoxZ TSC_c21100 6c4526d7126b05cfa72d46bc219c70de 108 TIGRFAM TIGR04490 SoxZ_true: thiosulfate oxidation carrier complex protein SoxZ 13 104 1.9E-28 T 12-10-2018 IPR030995 Thiosulfate oxidation carrier complex protein SoxZ TSC_c21100 6c4526d7126b05cfa72d46bc219c70de 108 SUPERFAMILY SSF81296 10 106 1.23E-25 T 12-10-2018 IPR014756 Immunoglobulin E-set TSC_c21100 6c4526d7126b05cfa72d46bc219c70de 108 Gene3D G3DSA:2.60.40.10 2 108 3.9E-37 T 12-10-2018 IPR013783 Immunoglobulin-like fold TSC_c06830 7ffb9b0d51033a50c20cbfce06244f58 138 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 7 137 1.3E-15 T 12-10-2018 IPR009936 Protein of unknown function DUF1468 TSC_c09170 8ed88ce970cb5375cb0f7e33aaafca4e 387 SUPERFAMILY SSF50249 141 209 7.64E-19 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c09170 8ed88ce970cb5375cb0f7e33aaafca4e 387 Pfam PF00575 S1 RNA binding domain 141 205 1.5E-12 T 12-10-2018 IPR003029 S1 domain GO:0003676 TSC_c09170 8ed88ce970cb5375cb0f7e33aaafca4e 387 Gene3D G3DSA:2.40.50.140 145 208 3.1E-23 T 12-10-2018 TSC_c09170 8ed88ce970cb5375cb0f7e33aaafca4e 387 Gene3D G3DSA:3.30.1480.10 1 138 7.3E-37 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 TSC_c09170 8ed88ce970cb5375cb0f7e33aaafca4e 387 SUPERFAMILY SSF54814 289 350 8.5E-13 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TSC_c09170 8ed88ce970cb5375cb0f7e33aaafca4e 387 SMART SM00322 311 372 5.3E-5 T 12-10-2018 IPR004087 K Homology domain GO:0003676 TSC_c09170 8ed88ce970cb5375cb0f7e33aaafca4e 387 SMART SM00322 240 303 34.0 T 12-10-2018 IPR004087 K Homology domain GO:0003676 TSC_c09170 8ed88ce970cb5375cb0f7e33aaafca4e 387 Pfam PF08529 NusA N-terminal domain 4 134 8.3E-32 T 12-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 TSC_c09170 8ed88ce970cb5375cb0f7e33aaafca4e 387 Pfam PF13184 NusA-like KH domain 240 307 3.6E-28 T 12-10-2018 IPR025249 KH domain, NusA-like GO:0003723 TSC_c09170 8ed88ce970cb5375cb0f7e33aaafca4e 387 SUPERFAMILY SSF54814 211 287 2.83E-29 T 12-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 TSC_c09170 8ed88ce970cb5375cb0f7e33aaafca4e 387 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 378 28.969 T 12-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 TSC_c09170 8ed88ce970cb5375cb0f7e33aaafca4e 387 Gene3D G3DSA:3.30.300.20 209 287 8.4E-34 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TSC_c09170 8ed88ce970cb5375cb0f7e33aaafca4e 387 Gene3D G3DSA:3.30.300.20 288 386 1.8E-24 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TSC_c09170 8ed88ce970cb5375cb0f7e33aaafca4e 387 SMART SM00316 143 208 1.0E-13 T 12-10-2018 IPR022967 RNA-binding domain, S1 TSC_c09170 8ed88ce970cb5375cb0f7e33aaafca4e 387 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 350 1.7E-123 T 12-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 TSC_c09170 8ed88ce970cb5375cb0f7e33aaafca4e 387 SUPERFAMILY SSF69705 1 136 9.42E-33 T 12-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 TSC_c12320 62a56a5e2ae1b21cb080e5254fdaa188 962 Pfam PF11867 Domain of unknown function (DUF3387) 632 958 9.0E-136 T 12-10-2018 IPR021810 Protein of unknown function DUF3387 TSC_c12320 62a56a5e2ae1b21cb080e5254fdaa188 962 SUPERFAMILY SSF52540 341 607 8.56E-6 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c12320 62a56a5e2ae1b21cb080e5254fdaa188 962 Gene3D G3DSA:3.40.50.300 196 397 6.6E-49 T 12-10-2018 TSC_c12320 62a56a5e2ae1b21cb080e5254fdaa188 962 Gene3D G3DSA:3.90.1570.50 26 186 4.0E-29 T 12-10-2018 TSC_c12320 62a56a5e2ae1b21cb080e5254fdaa188 962 Gene3D G3DSA:3.40.50.300 398 635 1.2E-44 T 12-10-2018 TSC_c12320 62a56a5e2ae1b21cb080e5254fdaa188 962 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 7 632 4.5E-178 T 12-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 TSC_c12320 62a56a5e2ae1b21cb080e5254fdaa188 962 SUPERFAMILY SSF52540 154 434 1.18E-24 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c12320 62a56a5e2ae1b21cb080e5254fdaa188 962 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 9 138 1.5E-34 T 12-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 TSC_c12320 62a56a5e2ae1b21cb080e5254fdaa188 962 SMART SM00487 196 412 2.2E-12 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSC_c12320 62a56a5e2ae1b21cb080e5254fdaa188 962 Pfam PF04851 Type III restriction enzyme, res subunit 213 378 7.2E-16 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TSC_c10780 7122613cfff1bb380823c27d24a2493c 355 SUPERFAMILY SSF51338 24 353 8.64E-7 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSC_c10780 7122613cfff1bb380823c27d24a2493c 355 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 24 350 1.2E-76 T 12-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 TSC_c10780 7122613cfff1bb380823c27d24a2493c 355 Gene3D G3DSA:3.20.20.140 40 320 1.4E-108 T 12-10-2018 TSC_c10780 7122613cfff1bb380823c27d24a2493c 355 Gene3D G3DSA:2.30.40.10 21 351 1.4E-108 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSC_c10780 7122613cfff1bb380823c27d24a2493c 355 Pfam PF01979 Amidohydrolase family 35 342 9.2E-17 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSC_c10780 7122613cfff1bb380823c27d24a2493c 355 SUPERFAMILY SSF51556 39 324 1.5E-84 T 12-10-2018 IPR032466 Metal-dependent hydrolase TSC_c10780 7122613cfff1bb380823c27d24a2493c 355 PIRSF PIRSF038994 13 355 7.2E-103 T 12-10-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 TSC_c17180 abc3516473172a6f0936a85ea050c8f1 478 SMART SM00849 12 196 4.4E-28 T 12-10-2018 IPR001279 Metallo-beta-lactamase TSC_c17180 abc3516473172a6f0936a85ea050c8f1 478 Pfam PF00753 Metallo-beta-lactamase superfamily 13 196 1.2E-13 T 12-10-2018 IPR001279 Metallo-beta-lactamase TSC_c17180 abc3516473172a6f0936a85ea050c8f1 478 ProSitePatterns PS00380 Rhodanese signature 1. 398 409 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TSC_c17180 abc3516473172a6f0936a85ea050c8f1 478 Gene3D G3DSA:3.40.250.10 364 474 1.6E-30 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c17180 abc3516473172a6f0936a85ea050c8f1 478 SMART SM00450 373 468 1.8E-26 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c17180 abc3516473172a6f0936a85ea050c8f1 478 SMART SM00450 273 368 6.3E-5 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c17180 abc3516473172a6f0936a85ea050c8f1 478 SUPERFAMILY SSF52821 369 474 2.23E-34 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c17180 abc3516473172a6f0936a85ea050c8f1 478 Pfam PF00581 Rhodanese-like domain 374 465 1.3E-15 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c17180 abc3516473172a6f0936a85ea050c8f1 478 Pfam PF00581 Rhodanese-like domain 279 361 5.9E-5 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c17180 abc3516473172a6f0936a85ea050c8f1 478 SUPERFAMILY SSF52821 239 371 3.67E-17 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c17180 abc3516473172a6f0936a85ea050c8f1 478 Gene3D G3DSA:3.40.250.10 266 359 7.4E-21 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c17180 abc3516473172a6f0936a85ea050c8f1 478 Gene3D G3DSA:3.60.15.10 1 262 8.0E-85 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c17180 abc3516473172a6f0936a85ea050c8f1 478 SUPERFAMILY SSF56281 1 261 3.92E-52 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c19020 ba034f44e6fbb29f92de5b6b2cfd305e 383 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 37 115 1.5E-7 T 12-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain TSC_c19020 ba034f44e6fbb29f92de5b6b2cfd305e 383 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 263 337 2.5E-20 T 12-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain TSC_c19020 ba034f44e6fbb29f92de5b6b2cfd305e 383 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 157 229 8.1E-7 T 12-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain TSC_c19490 5f429db01292c60a50a9f7f655bb6ac5 69 SMART SM00704 26 59 4.1E-11 T 12-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 TSC_c19490 5f429db01292c60a50a9f7f655bb6ac5 69 Gene3D G3DSA:3.40.5.90 1 68 2.0E-19 T 12-10-2018 TSC_c19490 5f429db01292c60a50a9f7f655bb6ac5 69 Pfam PF09360 Iron-binding zinc finger CDGSH type 8 54 1.8E-15 T 12-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 TSC_c15140 0de823e1752ed760de9fa3170a27accc 163 Gene3D G3DSA:3.40.50.2300 4 161 5.2E-64 T 12-10-2018 TSC_c15140 0de823e1752ed760de9fa3170a27accc 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 108 121 4.2E-23 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TSC_c15140 0de823e1752ed760de9fa3170a27accc 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 10 27 4.2E-23 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TSC_c15140 0de823e1752ed760de9fa3170a27accc 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 124 139 4.2E-23 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TSC_c15140 0de823e1752ed760de9fa3170a27accc 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 53 69 4.2E-23 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TSC_c15140 0de823e1752ed760de9fa3170a27accc 163 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 86 101 4.2E-23 T 12-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 TSC_c15140 0de823e1752ed760de9fa3170a27accc 163 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 10 150 1.0E-41 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TSC_c15140 0de823e1752ed760de9fa3170a27accc 163 SUPERFAMILY SSF52788 4 153 7.2E-50 T 12-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily TSC_c15140 0de823e1752ed760de9fa3170a27accc 163 SMART SM00226 8 152 1.3E-49 T 12-10-2018 IPR023485 Phosphotyrosine protein phosphatase I TSC_c01850 e4a133ce9a44cc3308b997c105ab03b3 376 Gene3D G3DSA:1.10.238.260 272 376 3.2E-34 T 12-10-2018 TSC_c01850 e4a133ce9a44cc3308b997c105ab03b3 376 Gene3D G3DSA:3.20.20.70 1 271 1.8E-108 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c01850 e4a133ce9a44cc3308b997c105ab03b3 376 TIGRFAM TIGR02146 LysS_fung_arch: homocitrate synthase 6 354 5.3E-160 T 12-10-2018 IPR011872 Homocitrate synthase, fungi/archaea GO:0004410|GO:0019752|GO:0019878|GO:0046912 KEGG: 00300+2.3.3.14|KEGG: 00620+2.3.3.14|MetaCyc: PWY-3081|MetaCyc: PWY-7710 TSC_c01850 e4a133ce9a44cc3308b997c105ab03b3 376 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSC_c01850 e4a133ce9a44cc3308b997c105ab03b3 376 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 192 205 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSC_c01850 e4a133ce9a44cc3308b997c105ab03b3 376 SUPERFAMILY SSF51569 2 282 1.15E-65 T 12-10-2018 TSC_c01850 e4a133ce9a44cc3308b997c105ab03b3 376 Pfam PF00682 HMGL-like 5 265 9.5E-68 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TSC_c10020 d648743e35fe28710d559714f20bd508 355 SUPERFAMILY SSF48452 33 167 3.37E-21 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c10020 d648743e35fe28710d559714f20bd508 355 SUPERFAMILY SSF48452 125 348 1.15E-34 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c10020 d648743e35fe28710d559714f20bd508 355 Pfam PF13181 Tetratricopeptide repeat 142 172 7.2E-6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c10020 d648743e35fe28710d559714f20bd508 355 Gene3D G3DSA:1.25.40.10 280 355 3.3E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c10020 d648743e35fe28710d559714f20bd508 355 SMART SM00028 29 62 0.53 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c10020 d648743e35fe28710d559714f20bd508 355 SMART SM00028 278 311 2.5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c10020 d648743e35fe28710d559714f20bd508 355 SMART SM00028 312 345 9.7 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c10020 d648743e35fe28710d559714f20bd508 355 SMART SM00028 176 208 1.6 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c10020 d648743e35fe28710d559714f20bd508 355 SMART SM00028 142 175 0.0055 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c10020 d648743e35fe28710d559714f20bd508 355 SMART SM00028 243 276 0.21 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c10020 d648743e35fe28710d559714f20bd508 355 Gene3D G3DSA:1.25.40.10 26 217 1.8E-54 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c10020 d648743e35fe28710d559714f20bd508 355 Gene3D G3DSA:1.25.40.10 218 279 2.3E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c10020 d648743e35fe28710d559714f20bd508 355 Pfam PF13432 Tetratricopeptide repeat 284 344 2.8E-5 T 12-10-2018 TSC_c10020 d648743e35fe28710d559714f20bd508 355 Pfam PF14559 Tetratricopeptide repeat 186 246 3.6E-9 T 12-10-2018 TSC_c10020 d648743e35fe28710d559714f20bd508 355 Pfam PF14559 Tetratricopeptide repeat 39 84 1.0E-9 T 12-10-2018 TSC_c12620 15550a2f8182ce6381593ef5c961f9bf 271 SUPERFAMILY SSF53098 50 259 9.86E-11 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c12620 15550a2f8182ce6381593ef5c961f9bf 271 Pfam PF01609 Transposase DDE domain 62 249 3.7E-32 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TSC_c15480 3f72104cecbeba6e5b9cfddf715ae345 438 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 6 436 2.9E-143 T 12-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 TSC_c15480 3f72104cecbeba6e5b9cfddf715ae345 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 353 369 4.3E-15 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c15480 3f72104cecbeba6e5b9cfddf715ae345 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 198 211 4.3E-15 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c15480 3f72104cecbeba6e5b9cfddf715ae345 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 182 194 4.3E-15 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c15480 3f72104cecbeba6e5b9cfddf715ae345 438 PRINTS PR01042 Aspartyl-tRNA synthetase signature 393 407 4.3E-15 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c15480 3f72104cecbeba6e5b9cfddf715ae345 438 Pfam PF01336 OB-fold nucleic acid binding domain 16 94 6.0E-16 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TSC_c15480 3f72104cecbeba6e5b9cfddf715ae345 438 Gene3D G3DSA:2.40.50.140 2 97 7.9E-24 T 12-10-2018 TSC_c15480 3f72104cecbeba6e5b9cfddf715ae345 438 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 1 438 41.925 T 12-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 TSC_c15480 3f72104cecbeba6e5b9cfddf715ae345 438 Pfam PF00152 tRNA synthetases class II (D, K and N) 113 432 8.3E-77 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c15480 3f72104cecbeba6e5b9cfddf715ae345 438 SUPERFAMILY SSF55681 111 432 5.39E-89 T 12-10-2018 TSC_c15480 3f72104cecbeba6e5b9cfddf715ae345 438 Gene3D G3DSA:3.30.930.10 102 438 1.2E-103 T 12-10-2018 TSC_c15480 3f72104cecbeba6e5b9cfddf715ae345 438 SUPERFAMILY SSF50249 4 96 4.5E-23 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c19050 5cf62ee4c4546f190f255a296d8cb6ab 126 SUPERFAMILY SSF51182 12 115 2.42E-29 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TSC_c19050 5cf62ee4c4546f190f255a296d8cb6ab 126 Pfam PF07883 Cupin domain 45 112 2.7E-21 T 12-10-2018 IPR013096 Cupin 2, conserved barrel TSC_c19050 5cf62ee4c4546f190f255a296d8cb6ab 126 Gene3D G3DSA:2.60.120.10 8 124 3.4E-33 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TSC_c21450 7ef685e80d93c6aae2106d8604248228 180 SUPERFAMILY SSF100950 9 178 1.95E-44 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TSC_c21450 7ef685e80d93c6aae2106d8604248228 180 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 12 173 3.3E-37 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase TSC_c21450 7ef685e80d93c6aae2106d8604248228 180 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 10 173 5.6E-29 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase TSC_c21450 7ef685e80d93c6aae2106d8604248228 180 PIRSF PIRSF006806 7 176 6.2E-35 T 12-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase TSC_c21450 7ef685e80d93c6aae2106d8604248228 180 Gene3D G3DSA:3.40.50.10420 8 180 1.7E-61 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily TSC_c10820 a339200272d3e187f1650ecf7c953b67 286 Gene3D G3DSA:3.40.50.10490 1 240 1.7E-68 T 12-10-2018 TSC_c10820 a339200272d3e187f1650ecf7c953b67 286 Pfam PF01380 SIS domain 119 185 1.3E-7 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TSC_c10820 a339200272d3e187f1650ecf7c953b67 286 SUPERFAMILY SSF53697 2 238 1.36E-52 T 12-10-2018 TSC_c10690 ecc4b4840b3de6394178079cec236ae9 265 SUPERFAMILY SSF161098 60 246 9.42E-24 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c10690 ecc4b4840b3de6394178079cec236ae9 265 Gene3D G3DSA:1.10.3720.10 55 265 1.7E-21 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c10690 ecc4b4840b3de6394178079cec236ae9 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 264 1.6E-27 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c06940 67c3bde57fe4e085eeae69abd57bb991 195 Gene3D G3DSA:3.30.70.20 64 115 8.9E-73 T 12-10-2018 TSC_c06940 67c3bde57fe4e085eeae69abd57bb991 195 Gene3D G3DSA:3.30.70.20 4 178 8.9E-73 T 12-10-2018 TSC_c06940 67c3bde57fe4e085eeae69abd57bb991 195 PRINTS PR00354 7Fe ferredoxin signature 85 102 7.6E-5 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSC_c06940 67c3bde57fe4e085eeae69abd57bb991 195 PRINTS PR00354 7Fe ferredoxin signature 58 68 7.6E-5 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSC_c06940 67c3bde57fe4e085eeae69abd57bb991 195 PRINTS PR00354 7Fe ferredoxin signature 68 78 7.6E-5 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSC_c06940 67c3bde57fe4e085eeae69abd57bb991 195 SUPERFAMILY SSF54862 1 178 1.05E-66 T 12-10-2018 TSC_c06940 67c3bde57fe4e085eeae69abd57bb991 195 Pfam PF13247 4Fe-4S dicluster domain 51 144 7.7E-25 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c06940 67c3bde57fe4e085eeae69abd57bb991 195 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 90 101 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c15400 1e0e1e8af8c5b265a1db82153c58da9a 418 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 415 30.649 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 TSC_c15400 1e0e1e8af8c5b265a1db82153c58da9a 418 SUPERFAMILY SSF52954 325 416 8.02E-21 T 12-10-2018 TSC_c15400 1e0e1e8af8c5b265a1db82153c58da9a 418 Pfam PF13393 Histidyl-tRNA synthetase 5 309 7.4E-40 T 12-10-2018 TSC_c15400 1e0e1e8af8c5b265a1db82153c58da9a 418 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 2 405 2.3E-138 T 12-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 TSC_c15400 1e0e1e8af8c5b265a1db82153c58da9a 418 SUPERFAMILY SSF55681 3 313 7.17E-92 T 12-10-2018 TSC_c15400 1e0e1e8af8c5b265a1db82153c58da9a 418 Pfam PF03129 Anticodon binding domain 327 414 1.3E-11 T 12-10-2018 IPR004154 Anticodon-binding TSC_c15400 1e0e1e8af8c5b265a1db82153c58da9a 418 Gene3D G3DSA:3.30.930.10 1 320 2.4E-105 T 12-10-2018 TSC_c15400 1e0e1e8af8c5b265a1db82153c58da9a 418 PIRSF PIRSF001549 1 416 3.8E-106 T 12-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 TSC_c15400 1e0e1e8af8c5b265a1db82153c58da9a 418 Gene3D G3DSA:3.40.50.800 321 415 6.3E-22 T 12-10-2018 IPR036621 Anticodon-binding domain superfamily TSC_c03800 625a8d667bd79f8260d41ef018fef3bd 252 SUPERFAMILY SSF110296 24 249 5.49E-24 T 12-10-2018 TSC_c03800 625a8d667bd79f8260d41ef018fef3bd 252 Gene3D G3DSA:2.130.10.10 44 250 9.2E-15 T 12-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 TSC_c04840 293dc1b8410af9422d82779d77426ee8 416 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 309 411 3.9E-24 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c04840 293dc1b8410af9422d82779d77426ee8 416 SUPERFAMILY SSF55874 264 411 7.86E-36 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c04840 293dc1b8410af9422d82779d77426ee8 416 SUPERFAMILY SSF47384 196 275 4.9E-16 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSC_c04840 293dc1b8410af9422d82779d77426ee8 416 Gene3D G3DSA:1.10.287.130 162 275 4.8E-23 T 12-10-2018 TSC_c04840 293dc1b8410af9422d82779d77426ee8 416 Gene3D G3DSA:3.30.565.10 276 415 2.2E-35 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c04840 293dc1b8410af9422d82779d77426ee8 416 SMART SM00388 213 275 9.4E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c04840 293dc1b8410af9422d82779d77426ee8 416 SMART SM00387 309 413 2.5E-37 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c04840 293dc1b8410af9422d82779d77426ee8 416 Pfam PF00512 His Kinase A (phospho-acceptor) domain 215 274 9.9E-16 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c04840 293dc1b8410af9422d82779d77426ee8 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 410 2.7E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c04840 293dc1b8410af9422d82779d77426ee8 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 392 2.7E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c04840 293dc1b8410af9422d82779d77426ee8 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 359 2.7E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c04840 293dc1b8410af9422d82779d77426ee8 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 373 2.7E-13 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c14510 09afc02ae52e0012392b23717f11c2e3 339 SUPERFAMILY SSF53756 2 337 6.04E-75 T 12-10-2018 TSC_c14510 09afc02ae52e0012392b23717f11c2e3 339 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 2 134 3.6E-28 T 12-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSC_c14510 09afc02ae52e0012392b23717f11c2e3 339 Gene3D G3DSA:3.40.50.2000 159 301 1.5E-79 T 12-10-2018 TSC_c14510 09afc02ae52e0012392b23717f11c2e3 339 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 2 339 26.894 T 12-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSC_c14510 09afc02ae52e0012392b23717f11c2e3 339 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 182 301 5.6E-21 T 12-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 TSC_c14510 09afc02ae52e0012392b23717f11c2e3 339 Gene3D G3DSA:3.40.50.2000 3 158 1.5E-79 T 12-10-2018 TSC_c15520 c826866ff394e605f6b9f1132fc22b0c 188 PIRSF PIRSF005639 1 187 2.8E-66 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TSC_c15520 c826866ff394e605f6b9f1132fc22b0c 188 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 2 184 3.0E-67 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TSC_c15520 c826866ff394e605f6b9f1132fc22b0c 188 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 2 185 37.193 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TSC_c15520 c826866ff394e605f6b9f1132fc22b0c 188 SUPERFAMILY SSF52317 2 185 5.73E-47 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c15520 c826866ff394e605f6b9f1132fc22b0c 188 Pfam PF01174 SNO glutamine amidotransferase family 4 184 8.0E-59 T 12-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TSC_c15520 c826866ff394e605f6b9f1132fc22b0c 188 ProSitePatterns PS01236 PdxT/SNO family family signature. 39 49 - T 12-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TSC_c15520 c826866ff394e605f6b9f1132fc22b0c 188 Gene3D G3DSA:3.40.50.880 1 187 2.0E-65 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c24770 2b4007add60bf0dcc27923c7905e47ad 239 SUPERFAMILY SSF52540 2 221 4.64E-61 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c24770 2b4007add60bf0dcc27923c7905e47ad 239 Pfam PF00005 ABC transporter 18 161 1.4E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c24770 2b4007add60bf0dcc27923c7905e47ad 239 Gene3D G3DSA:3.40.50.300 1 238 1.5E-65 T 12-10-2018 TSC_c24770 2b4007add60bf0dcc27923c7905e47ad 239 SMART SM00382 26 209 2.5E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c22270 5c3a2d1b33a9499c460a56a3c4258236 157 Pfam PF00333 Ribosomal protein S5, N-terminal domain 6 70 1.5E-24 T 12-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 TSC_c22270 5c3a2d1b33a9499c460a56a3c4258236 157 SUPERFAMILY SSF54211 74 152 2.3E-24 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c22270 5c3a2d1b33a9499c460a56a3c4258236 157 SUPERFAMILY SSF54768 4 71 5.13E-21 T 12-10-2018 TSC_c22270 5c3a2d1b33a9499c460a56a3c4258236 157 Gene3D G3DSA:3.30.230.10 69 143 3.8E-34 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSC_c22270 5c3a2d1b33a9499c460a56a3c4258236 157 Pfam PF03719 Ribosomal protein S5, C-terminal domain 82 152 2.1E-29 T 12-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 TSC_c22270 5c3a2d1b33a9499c460a56a3c4258236 157 Gene3D G3DSA:3.30.160.20 1 68 1.2E-28 T 12-10-2018 TSC_c22270 5c3a2d1b33a9499c460a56a3c4258236 157 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 157 31.918 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 TSC_c22270 5c3a2d1b33a9499c460a56a3c4258236 157 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 3 153 2.6E-61 T 12-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 TSC_c22270 5c3a2d1b33a9499c460a56a3c4258236 157 ProSitePatterns PS00585 Ribosomal protein S5 signature. 23 55 - T 12-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site TSC_c02610 d7304563a56d388ce112f7364e34fe97 226 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c02610 d7304563a56d388ce112f7364e34fe97 226 SUPERFAMILY SSF52540 2 222 1.95E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c02610 d7304563a56d388ce112f7364e34fe97 226 Pfam PF00005 ABC transporter 22 170 8.7E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c02610 d7304563a56d388ce112f7364e34fe97 226 Gene3D G3DSA:3.40.50.300 1 225 4.1E-69 T 12-10-2018 TSC_c02610 d7304563a56d388ce112f7364e34fe97 226 SMART SM00382 31 218 1.2E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c11560 8053d6cab4cd437f066d41bd523d60ce 306 TIGRFAM TIGR03215 ac_ald_DH_ac: acetaldehyde dehydrogenase (acetylating) 3 296 1.9E-135 T 12-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 TSC_c11560 8053d6cab4cd437f066d41bd523d60ce 306 Gene3D G3DSA:3.40.50.720 5 290 9.2E-117 T 12-10-2018 TSC_c11560 8053d6cab4cd437f066d41bd523d60ce 306 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 115 2.6E-13 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSC_c11560 8053d6cab4cd437f066d41bd523d60ce 306 SUPERFAMILY SSF51735 1 150 5.86E-30 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c11560 8053d6cab4cd437f066d41bd523d60ce 306 Pfam PF09290 Prokaryotic acetaldehyde dehydrogenase, dimerisation 126 272 1.0E-55 T 12-10-2018 IPR015426 Acetaldehyde dehydrogenase, C-terminal GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 TSC_c11560 8053d6cab4cd437f066d41bd523d60ce 306 SUPERFAMILY SSF55347 126 273 2.03E-55 T 12-10-2018 TSC_c11560 8053d6cab4cd437f066d41bd523d60ce 306 SMART SM00859 5 118 1.0E-12 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSC_c11560 8053d6cab4cd437f066d41bd523d60ce 306 PIRSF PIRSF015689 1 303 1.4E-123 T 12-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 TSC_c11560 8053d6cab4cd437f066d41bd523d60ce 306 Gene3D G3DSA:3.30.360.10 126 272 9.2E-117 T 12-10-2018 TSC_c11560 8053d6cab4cd437f066d41bd523d60ce 306 Hamap MF_01657 Acetaldehyde dehydrogenase [mhpF]. 1 306 131.979 T 12-10-2018 IPR003361 Acetaldehyde dehydrogenase GO:0008774|GO:0019439|GO:0055114 KEGG: 00360+1.2.1.10|KEGG: 00362+1.2.1.10|KEGG: 00620+1.2.1.10|KEGG: 00621+1.2.1.10|KEGG: 00622+1.2.1.10|KEGG: 00650+1.2.1.10|MetaCyc: PWY-5162|MetaCyc: PWY-5436|MetaCyc: PWY-5480|MetaCyc: PWY-6587|MetaCyc: PWY-7085|MetaCyc: PWY-7180 TSC_c13100 27fd1bd44b87d0edce8d84e73bcaac72 332 PIRSF PIRSF000164 1 307 1.3E-37 T 12-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 TSC_c13100 27fd1bd44b87d0edce8d84e73bcaac72 332 Pfam PF01180 Dihydroorotate dehydrogenase 95 290 2.1E-10 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 TSC_c13100 27fd1bd44b87d0edce8d84e73bcaac72 332 SUPERFAMILY SSF51395 1 306 6.48E-56 T 12-10-2018 TSC_c13100 27fd1bd44b87d0edce8d84e73bcaac72 332 Gene3D G3DSA:3.20.20.70 1 307 1.2E-52 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c19770 39ebf17d5f97148885a4ec88b6ea1cd6 177 Gene3D G3DSA:2.40.380.10 64 168 1.5E-9 T 12-10-2018 IPR035930 FomD-like superfamily TSC_c19770 39ebf17d5f97148885a4ec88b6ea1cd6 177 SUPERFAMILY SSF159234 27 166 6.15E-20 T 12-10-2018 IPR035930 FomD-like superfamily TSC_c19770 39ebf17d5f97148885a4ec88b6ea1cd6 177 Pfam PF04167 Protein of unknown function (DUF402) 68 131 2.3E-10 T 12-10-2018 IPR007295 Domain of unknown function DUF402 TSC_c22970 1a73dfc71ffd5a7df5d37415985234d9 256 SUPERFAMILY SSF51735 5 247 2.9E-78 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c22970 1a73dfc71ffd5a7df5d37415985234d9 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 3.8E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c22970 1a73dfc71ffd5a7df5d37415985234d9 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 3.8E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c22970 1a73dfc71ffd5a7df5d37415985234d9 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 3.8E-14 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c22970 1a73dfc71ffd5a7df5d37415985234d9 256 Gene3D G3DSA:3.40.50.720 1 256 6.6E-85 T 12-10-2018 TSC_c22970 1a73dfc71ffd5a7df5d37415985234d9 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 246 3.2E-68 T 12-10-2018 TSC_c22970 1a73dfc71ffd5a7df5d37415985234d9 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 9.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c22970 1a73dfc71ffd5a7df5d37415985234d9 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 9.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c22970 1a73dfc71ffd5a7df5d37415985234d9 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 9.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c22970 1a73dfc71ffd5a7df5d37415985234d9 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 9.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c22970 1a73dfc71ffd5a7df5d37415985234d9 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 9.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c22970 1a73dfc71ffd5a7df5d37415985234d9 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 9.3E-46 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c22970 1a73dfc71ffd5a7df5d37415985234d9 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSC_c21050 ebf27e857f7284378b3e4fb3f7345134 267 Gene3D G3DSA:1.10.760.10 141 256 8.2E-28 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c21050 ebf27e857f7284378b3e4fb3f7345134 267 SUPERFAMILY SSF46626 43 148 1.43E-20 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c21050 ebf27e857f7284378b3e4fb3f7345134 267 TIGRFAM TIGR04484 thiosulf_SoxA: sulfur oxidation c-type cytochrome SoxA 52 259 2.4E-68 T 12-10-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 TSC_c21050 ebf27e857f7284378b3e4fb3f7345134 267 Gene3D G3DSA:1.10.760.10 54 140 6.2E-21 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c21050 ebf27e857f7284378b3e4fb3f7345134 267 PIRSF PIRSF038455 2 267 7.0E-70 T 12-10-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 TSC_c21050 ebf27e857f7284378b3e4fb3f7345134 267 SUPERFAMILY SSF46626 153 252 4.33E-27 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c11480 204582f7332537c3f87ad277fab56d7d 445 SUPERFAMILY SSF50022 24 168 8.77E-49 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSC_c11480 204582f7332537c3f87ad277fab56d7d 445 Pfam PF00848 Ring hydroxylating alpha subunit (catalytic domain) 173 444 7.1E-24 T 12-10-2018 IPR015879 Aromatic-ring-hydroxylating dioxygenase, alpha subunit, C-terminal domain GO:0005506|GO:0044237|GO:0051537|GO:0055114 TSC_c11480 204582f7332537c3f87ad277fab56d7d 445 ProSitePatterns PS00570 Bacterial ring hydroxylating dioxygenases alpha-subunit signature. 94 117 - T 12-10-2018 IPR015881 Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site GO:0005506|GO:0051537|GO:0055114 TSC_c11480 204582f7332537c3f87ad277fab56d7d 445 Gene3D G3DSA:3.90.380.10 33 443 5.3E-156 T 12-10-2018 TSC_c11480 204582f7332537c3f87ad277fab56d7d 445 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 36 61 4.8E-42 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 TSC_c11480 204582f7332537c3f87ad277fab56d7d 445 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 193 215 4.8E-42 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 TSC_c11480 204582f7332537c3f87ad277fab56d7d 445 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 87 107 4.8E-42 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 TSC_c11480 204582f7332537c3f87ad277fab56d7d 445 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 108 128 4.8E-42 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 TSC_c11480 204582f7332537c3f87ad277fab56d7d 445 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 66 81 4.8E-42 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 TSC_c11480 204582f7332537c3f87ad277fab56d7d 445 PRINTS PR00090 Ring hydroxylating dioxygenase alpha-subunit signature 152 178 4.8E-42 T 12-10-2018 IPR001663 Aromatic-ring-hydroxylating dioxygenase, alpha subunit GO:0044237|GO:0051537|GO:0055114 TSC_c11480 204582f7332537c3f87ad277fab56d7d 445 Gene3D G3DSA:2.102.10.10 51 176 5.3E-156 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSC_c11480 204582f7332537c3f87ad277fab56d7d 445 Pfam PF00355 Rieske [2Fe-2S] domain 51 135 4.4E-22 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TSC_c11480 204582f7332537c3f87ad277fab56d7d 445 SUPERFAMILY SSF55961 169 444 1.01E-59 T 12-10-2018 TSC_c05430 ddc0eb4ef10b075fb667d1aceea51cd7 467 Pfam PF02913 FAD linked oxidases, C-terminal domain 212 452 4.6E-69 T 12-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 TSC_c05430 ddc0eb4ef10b075fb667d1aceea51cd7 467 Gene3D G3DSA:3.30.70.2190 213 325 9.4E-7 T 12-10-2018 TSC_c05430 ddc0eb4ef10b075fb667d1aceea51cd7 467 Gene3D G3DSA:3.30.465.10 92 212 2.1E-35 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSC_c05430 ddc0eb4ef10b075fb667d1aceea51cd7 467 Gene3D G3DSA:3.30.43.10 2 90 2.5E-24 T 12-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 TSC_c05430 ddc0eb4ef10b075fb667d1aceea51cd7 467 SUPERFAMILY SSF56176 2 213 7.01E-69 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSC_c05430 ddc0eb4ef10b075fb667d1aceea51cd7 467 Gene3D G3DSA:1.10.45.10 413 453 5.1E-9 T 12-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 TSC_c05430 ddc0eb4ef10b075fb667d1aceea51cd7 467 Gene3D G3DSA:3.30.70.2740 331 412 1.3E-8 T 12-10-2018 TSC_c05430 ddc0eb4ef10b075fb667d1aceea51cd7 467 Pfam PF01565 FAD binding domain 38 177 2.3E-42 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TSC_c05430 ddc0eb4ef10b075fb667d1aceea51cd7 467 SUPERFAMILY SSF55103 216 455 6.21E-72 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TSC_c19900 f3cf4f8a3596d35c93a57656094c22eb 468 Pfam PF13641 Glycosyltransferase like family 2 61 325 9.7E-29 T 12-10-2018 TSC_c19900 f3cf4f8a3596d35c93a57656094c22eb 468 Gene3D G3DSA:3.90.550.10 48 314 6.4E-43 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c19900 f3cf4f8a3596d35c93a57656094c22eb 468 SUPERFAMILY SSF53448 60 372 5.32E-52 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c01000 0127e0586458595043422ea5aac09815 264 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 188 236 - T 12-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c01000 0127e0586458595043422ea5aac09815 264 PRINTS PR01166 Cytochrome c oxidase subunit II signature 163 184 1.5E-11 T 12-10-2018 TSC_c01000 0127e0586458595043422ea5aac09815 264 PRINTS PR01166 Cytochrome c oxidase subunit II signature 187 207 1.5E-11 T 12-10-2018 TSC_c01000 0127e0586458595043422ea5aac09815 264 PRINTS PR01166 Cytochrome c oxidase subunit II signature 111 130 1.5E-11 T 12-10-2018 TSC_c01000 0127e0586458595043422ea5aac09815 264 PRINTS PR01166 Cytochrome c oxidase subunit II signature 225 242 1.5E-11 T 12-10-2018 TSC_c01000 0127e0586458595043422ea5aac09815 264 Gene3D G3DSA:1.10.287.90 52 110 1.5E-52 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c01000 0127e0586458595043422ea5aac09815 264 Gene3D G3DSA:2.60.40.420 111 252 1.5E-52 T 12-10-2018 IPR008972 Cupredoxin TSC_c01000 0127e0586458595043422ea5aac09815 264 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 116 236 7.1E-17 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c01000 0127e0586458595043422ea5aac09815 264 SUPERFAMILY SSF49503 111 255 2.32E-44 T 12-10-2018 IPR008972 Cupredoxin TSC_c22910 e0e0842bb7d3f1f6126189d203cfdef9 311 Gene3D G3DSA:3.40.50.150 9 197 8.6E-51 T 12-10-2018 TSC_c22910 e0e0842bb7d3f1f6126189d203cfdef9 311 Pfam PF02390 Putative methyltransferase 23 186 2.6E-39 T 12-10-2018 TSC_c22910 e0e0842bb7d3f1f6126189d203cfdef9 311 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 15 183 1.7E-37 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 TSC_c22910 e0e0842bb7d3f1f6126189d203cfdef9 311 SUPERFAMILY SSF53335 14 190 3.99E-26 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c22910 e0e0842bb7d3f1f6126189d203cfdef9 311 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 192 26.454 T 12-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 TSC_c12040 6f51f064f138534948a10e7ec468b407 450 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 252 439 4.1E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c12040 6f51f064f138534948a10e7ec468b407 450 Gene3D G3DSA:1.10.3720.10 193 437 7.7E-56 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c12040 6f51f064f138534948a10e7ec468b407 450 SUPERFAMILY SSF161098 204 449 7.19E-60 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c18020 e804278c519ece35653bd49a475663d4 340 SUPERFAMILY SSF55729 7 149 3.87E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSC_c18020 e804278c519ece35653bd49a475663d4 340 SUPERFAMILY SSF55729 140 314 3.07E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSC_c18020 e804278c519ece35653bd49a475663d4 340 Pfam PF02388 FemAB family 17 86 2.3E-5 T 12-10-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 TSC_c18020 e804278c519ece35653bd49a475663d4 340 Pfam PF02388 FemAB family 219 311 5.9E-14 T 12-10-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 TSC_c18020 e804278c519ece35653bd49a475663d4 340 Pfam PF02388 FemAB family 124 205 4.7E-6 T 12-10-2018 IPR003447 FemABX peptidyl transferase GO:0016755|GO:0044038 TSC_c18020 e804278c519ece35653bd49a475663d4 340 Gene3D G3DSA:3.40.630.30 3 100 3.2E-14 T 12-10-2018 TSC_c18020 e804278c519ece35653bd49a475663d4 340 Gene3D G3DSA:3.40.630.30 120 303 2.1E-42 T 12-10-2018 TSC_c01250 ae2d8400e83b7c53fa130565fec0aed0 376 Pfam PF00155 Aminotransferase class I and II 27 369 2.0E-34 T 12-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 TSC_c01250 ae2d8400e83b7c53fa130565fec0aed0 376 Gene3D G3DSA:3.90.1150.10 27 369 1.1E-120 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c01250 ae2d8400e83b7c53fa130565fec0aed0 376 SUPERFAMILY SSF53383 18 375 1.17E-86 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c01250 ae2d8400e83b7c53fa130565fec0aed0 376 Gene3D G3DSA:3.40.640.10 58 276 1.1E-120 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c01250 ae2d8400e83b7c53fa130565fec0aed0 376 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 227 240 - T 12-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 TSC_c09820 7c3f2785d1a2a5a4c9716d2dbb93c5de 283 Gene3D G3DSA:3.40.50.720 7 254 3.2E-108 T 12-10-2018 TSC_c09820 7c3f2785d1a2a5a4c9716d2dbb93c5de 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 72 99 1.2E-74 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSC_c09820 7c3f2785d1a2a5a4c9716d2dbb93c5de 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 251 269 1.2E-74 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSC_c09820 7c3f2785d1a2a5a4c9716d2dbb93c5de 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 107 128 1.2E-74 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSC_c09820 7c3f2785d1a2a5a4c9716d2dbb93c5de 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 31 53 1.2E-74 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSC_c09820 7c3f2785d1a2a5a4c9716d2dbb93c5de 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 152 172 1.2E-74 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSC_c09820 7c3f2785d1a2a5a4c9716d2dbb93c5de 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 201 230 1.2E-74 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSC_c09820 7c3f2785d1a2a5a4c9716d2dbb93c5de 283 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 121 274 3.4E-69 T 12-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSC_c09820 7c3f2785d1a2a5a4c9716d2dbb93c5de 283 Gene3D G3DSA:3.40.50.10860 9 272 3.2E-108 T 12-10-2018 TSC_c09820 7c3f2785d1a2a5a4c9716d2dbb93c5de 283 SUPERFAMILY SSF51735 120 274 3.08E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c09820 7c3f2785d1a2a5a4c9716d2dbb93c5de 283 SUPERFAMILY SSF53223 4 119 5.28E-33 T 12-10-2018 TSC_c09820 7c3f2785d1a2a5a4c9716d2dbb93c5de 283 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 255 263 - T 12-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSC_c09820 7c3f2785d1a2a5a4c9716d2dbb93c5de 283 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 7 118 5.8E-32 T 12-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSC_c09820 7c3f2785d1a2a5a4c9716d2dbb93c5de 283 Hamap MF_01576 Bifunctional protein FolD [folD]. 4 278 37.787 T 12-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 TSC_c24900 16eb972bdcb56975b87d10c5a4784e3a 219 SUPERFAMILY SSF56176 2 113 9.81E-14 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSC_c24900 16eb972bdcb56975b87d10c5a4784e3a 219 Gene3D G3DSA:3.30.70.2560 115 173 3.8E-28 T 12-10-2018 TSC_c24900 16eb972bdcb56975b87d10c5a4784e3a 219 Gene3D G3DSA:3.30.465.10 1 114 5.1E-32 T 12-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 TSC_c10440 7c8fb2d464d4d42694fe3dae15eb3416 516 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 270 277 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TSC_c10440 7c8fb2d464d4d42694fe3dae15eb3416 516 Gene3D G3DSA:3.40.605.10 40 499 3.9E-190 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSC_c10440 7c8fb2d464d4d42694fe3dae15eb3416 516 SUPERFAMILY SSF53720 26 505 1.96E-163 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSC_c10440 7c8fb2d464d4d42694fe3dae15eb3416 516 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 298 309 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TSC_c10440 7c8fb2d464d4d42694fe3dae15eb3416 516 TIGRFAM TIGR02299 HpaE: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase 28 515 3.4E-246 T 12-10-2018 IPR011985 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase GO:0018480|GO:1901023 TSC_c10440 7c8fb2d464d4d42694fe3dae15eb3416 516 Pfam PF00171 Aldehyde dehydrogenase family 37 501 3.5E-170 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSC_c10440 7c8fb2d464d4d42694fe3dae15eb3416 516 Gene3D G3DSA:3.40.309.10 274 474 3.9E-190 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSC_c02800 01babe9036c84f0f9b75f6fc23b17088 543 SUPERFAMILY SSF52540 7 540 4.72E-208 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c02800 01babe9036c84f0f9b75f6fc23b17088 543 Gene3D G3DSA:3.40.50.300 5 424 6.9E-176 T 12-10-2018 TSC_c02800 01babe9036c84f0f9b75f6fc23b17088 543 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 317 328 - T 12-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 TSC_c02800 01babe9036c84f0f9b75f6fc23b17088 543 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 2 543 44.249 T 12-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 TSC_c02800 01babe9036c84f0f9b75f6fc23b17088 543 Gene3D G3DSA:3.30.1510.10 118 236 6.9E-176 T 12-10-2018 TSC_c02800 01babe9036c84f0f9b75f6fc23b17088 543 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 92 102 - T 12-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 TSC_c02800 01babe9036c84f0f9b75f6fc23b17088 543 Gene3D G3DSA:3.10.410.10 429 517 3.0E-29 T 12-10-2018 TSC_c02800 01babe9036c84f0f9b75f6fc23b17088 543 Pfam PF01268 Formate--tetrahydrofolate ligase 5 541 1.8E-222 T 12-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 TSC_c06920 509a923d4d31951d5244ff195587b4a7 146 SUPERFAMILY SSF52821 39 146 2.1E-33 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c06920 509a923d4d31951d5244ff195587b4a7 146 SMART SM00450 49 143 6.4E-29 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c06920 509a923d4d31951d5244ff195587b4a7 146 Gene3D G3DSA:3.40.250.10 47 146 1.1E-30 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c06920 509a923d4d31951d5244ff195587b4a7 146 Pfam PF00581 Rhodanese-like domain 51 138 9.1E-20 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c24910 8d53a8af2992a61a2707ae5302421b39 353 SUPERFAMILY SSF46589 9 95 4.03E-19 T 12-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 TSC_c24910 8d53a8af2992a61a2707ae5302421b39 353 SUPERFAMILY SSF55681 90 350 2.04E-75 T 12-10-2018 TSC_c24910 8d53a8af2992a61a2707ae5302421b39 353 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 36 349 2.5E-93 T 12-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 TSC_c24910 8d53a8af2992a61a2707ae5302421b39 353 Pfam PF01409 tRNA synthetases class II core domain (F) 90 349 8.1E-98 T 12-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 TSC_c24910 8d53a8af2992a61a2707ae5302421b39 353 Gene3D G3DSA:3.30.930.10 4 353 7.7E-123 T 12-10-2018 TSC_c24910 8d53a8af2992a61a2707ae5302421b39 353 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 17 84 6.1E-19 T 12-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 TSC_c24910 8d53a8af2992a61a2707ae5302421b39 353 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 5 349 45.074 T 12-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 TSC_p800110 d3f8ce560033ffc426e26c81b200ea84 155 Pfam PF00293 NUDIX domain 7 120 2.0E-21 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSC_p800110 d3f8ce560033ffc426e26c81b200ea84 155 SUPERFAMILY SSF55811 4 134 1.0E-25 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSC_p800110 d3f8ce560033ffc426e26c81b200ea84 155 Gene3D G3DSA:3.90.79.10 2 139 2.2E-26 T 12-10-2018 TSC_p800110 d3f8ce560033ffc426e26c81b200ea84 155 PRINTS PR00502 NUDIX hydrolase family signature 48 63 2.2E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSC_p800110 d3f8ce560033ffc426e26c81b200ea84 155 PRINTS PR00502 NUDIX hydrolase family signature 34 48 2.2E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSC_p800110 d3f8ce560033ffc426e26c81b200ea84 155 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TSC_c21200 09895348a6f3a89dfa801343662e40f3 128 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 128 31.466 T 12-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid TSC_c21200 09895348a6f3a89dfa801343662e40f3 128 Gene3D G3DSA:3.30.230.10 1 128 2.4E-53 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSC_c21200 09895348a6f3a89dfa801343662e40f3 128 Pfam PF00380 Ribosomal protein S9/S16 8 128 2.9E-43 T 12-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 TSC_c21200 09895348a6f3a89dfa801343662e40f3 128 SUPERFAMILY SSF54211 3 128 1.57E-45 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c21200 09895348a6f3a89dfa801343662e40f3 128 ProSitePatterns PS00360 Ribosomal protein S9 signature. 67 85 - T 12-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 TSC_c00720 56ea1cdabf9f400141711bed5d91d377 93 Pfam PF02583 Metal-sensitive transcriptional repressor 13 91 1.1E-23 T 12-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 TSC_c00720 56ea1cdabf9f400141711bed5d91d377 93 Gene3D G3DSA:1.20.58.1000 1 93 1.5E-25 T 12-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily TSC_c04150 ab9073cc4987f4c6e4bd96f119cc0a02 340 SUPERFAMILY SSF52540 4 268 2.92E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c04150 ab9073cc4987f4c6e4bd96f119cc0a02 340 Hamap MF_00268 Protein RecA [recA]. 5 330 51.264 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSC_c04150 ab9073cc4987f4c6e4bd96f119cc0a02 340 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 324 3.8E-165 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSC_c04150 ab9073cc4987f4c6e4bd96f119cc0a02 340 ProSitePatterns PS00321 recA signature. 213 221 - T 12-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 TSC_c04150 ab9073cc4987f4c6e4bd96f119cc0a02 340 SMART SM00382 57 228 6.0E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c04150 ab9073cc4987f4c6e4bd96f119cc0a02 340 Gene3D G3DSA:3.40.50.300 26 268 3.6E-82 T 12-10-2018 TSC_c04150 ab9073cc4987f4c6e4bd96f119cc0a02 340 SUPERFAMILY SSF54752 273 325 3.14E-16 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal TSC_c04150 ab9073cc4987f4c6e4bd96f119cc0a02 340 Gene3D G3DSA:3.30.250.10 269 327 5.5E-22 T 12-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal TSC_c04150 ab9073cc4987f4c6e4bd96f119cc0a02 340 Pfam PF00154 recA bacterial DNA recombination protein 7 268 1.1E-138 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSC_c04150 ab9073cc4987f4c6e4bd96f119cc0a02 340 PRINTS PR00142 RecA protein signature 93 122 1.1E-76 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSC_c04150 ab9073cc4987f4c6e4bd96f119cc0a02 340 PRINTS PR00142 RecA protein signature 165 194 1.1E-76 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSC_c04150 ab9073cc4987f4c6e4bd96f119cc0a02 340 PRINTS PR00142 RecA protein signature 210 238 1.1E-76 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSC_c04150 ab9073cc4987f4c6e4bd96f119cc0a02 340 PRINTS PR00142 RecA protein signature 127 156 1.1E-76 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSC_c04150 ab9073cc4987f4c6e4bd96f119cc0a02 340 PRINTS PR00142 RecA protein signature 244 273 1.1E-76 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSC_c04150 ab9073cc4987f4c6e4bd96f119cc0a02 340 PRINTS PR00142 RecA protein signature 298 315 1.1E-76 T 12-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 TSC_c10300 97f7941494487dd3bf4810c0634aa37d 152 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 36.539 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 TSC_c10300 97f7941494487dd3bf4810c0634aa37d 152 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 3.6E-56 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 TSC_c10300 97f7941494487dd3bf4810c0634aa37d 152 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 9.1E-57 T 12-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 TSC_c10300 97f7941494487dd3bf4810c0634aa37d 152 SUPERFAMILY SSF69500 1 145 3.92E-58 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily TSC_c10300 97f7941494487dd3bf4810c0634aa37d 152 Gene3D G3DSA:3.50.80.10 1 148 2.4E-58 T 12-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily TSC_c13990 43ad7fe04124f1a754441dbf72e1492d 156 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 119 135 - T 12-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 TSC_c13990 43ad7fe04124f1a754441dbf72e1492d 156 SUPERFAMILY SSF54534 82 154 4.84E-18 T 12-10-2018 TSC_c13990 43ad7fe04124f1a754441dbf72e1492d 156 SUPERFAMILY SSF46557 4 77 6.15E-22 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 TSC_c13990 43ad7fe04124f1a754441dbf72e1492d 156 Hamap MF_00105 Transcription elongation factor GreA [greA]. 3 154 26.654 T 12-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 TSC_c13990 43ad7fe04124f1a754441dbf72e1492d 156 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 6 154 6.9E-53 T 12-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 TSC_c13990 43ad7fe04124f1a754441dbf72e1492d 156 Gene3D G3DSA:1.10.287.180 2 76 2.0E-24 T 12-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 TSC_c13990 43ad7fe04124f1a754441dbf72e1492d 156 PIRSF PIRSF006092 1 156 6.6E-55 T 12-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 TSC_c13990 43ad7fe04124f1a754441dbf72e1492d 156 Gene3D G3DSA:3.10.50.30 77 154 6.2E-22 T 12-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 TSC_c13990 43ad7fe04124f1a754441dbf72e1492d 156 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 154 9.6E-25 T 12-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 TSC_c13990 43ad7fe04124f1a754441dbf72e1492d 156 Pfam PF03449 Transcription elongation factor, N-terminal 5 75 4.3E-26 T 12-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 TSC_c07610 16cf94b86d0b06790e71a6433ddc9125 179 SUPERFAMILY SSF52980 4 172 3.06E-21 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSC_c07610 16cf94b86d0b06790e71a6433ddc9125 179 Gene3D G3DSA:3.90.1570.10 3 178 5.8E-18 T 12-10-2018 TSC_c07610 16cf94b86d0b06790e71a6433ddc9125 179 Pfam PF05685 Putative restriction endonuclease 9 165 1.5E-32 T 12-10-2018 IPR008538 Domain of unknown function DUF820 TSC_c13040 8804dac19550294c80b0679012240e9c 313 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 188 271 1.7E-35 T 12-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 TSC_c13040 8804dac19550294c80b0679012240e9c 313 Pfam PF01012 Electron transfer flavoprotein domain 3 168 8.2E-21 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TSC_c13040 8804dac19550294c80b0679012240e9c 313 SMART SM00893 2 184 3.4E-14 T 12-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 TSC_c13040 8804dac19550294c80b0679012240e9c 313 SUPERFAMILY SSF52402 2 181 1.51E-24 T 12-10-2018 TSC_c13040 8804dac19550294c80b0679012240e9c 313 SUPERFAMILY SSF52467 186 307 1.58E-48 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSC_c13040 8804dac19550294c80b0679012240e9c 313 PIRSF PIRSF000089 1 313 1.1E-93 T 12-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 TSC_c13040 8804dac19550294c80b0679012240e9c 313 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 252 278 - T 12-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 TSC_c13040 8804dac19550294c80b0679012240e9c 313 Gene3D G3DSA:3.40.50.620 1 185 9.5E-26 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c13040 8804dac19550294c80b0679012240e9c 313 Gene3D G3DSA:3.40.50.1220 186 313 2.5E-58 T 12-10-2018 TSC_c05530 b002ad6942ad1d5c036bffefd40730f9 291 SUPERFAMILY SSF109604 106 189 1.54E-8 T 12-10-2018 TSC_c05530 b002ad6942ad1d5c036bffefd40730f9 291 Pfam PF01966 HD domain 85 189 1.4E-4 T 12-10-2018 IPR006674 HD domain TSC_c05530 b002ad6942ad1d5c036bffefd40730f9 291 Gene3D G3DSA:1.10.3210.10 55 205 3.3E-7 T 12-10-2018 TSC_c07540 3ed98cc707bd8dbf9e49754caaa87ddc 286 Gene3D G3DSA:1.10.3720.10 5 284 2.5E-48 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c07540 3ed98cc707bd8dbf9e49754caaa87ddc 286 SUPERFAMILY SSF161098 15 277 2.49E-47 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c07540 3ed98cc707bd8dbf9e49754caaa87ddc 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 276 5.0E-10 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 Gene3D G3DSA:1.25.40.10 394 460 3.3E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 SUPERFAMILY SSF48452 133 260 5.18E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 SUPERFAMILY SSF48452 30 157 5.69E-25 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 Gene3D G3DSA:1.25.40.10 14 247 1.6E-34 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 Pfam PF13432 Tetratricopeptide repeat 391 448 2.2E-6 T 12-10-2018 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 Pfam PF13432 Tetratricopeptide repeat 35 89 2.8E-10 T 12-10-2018 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 Pfam PF13432 Tetratricopeptide repeat 250 294 6.1E-5 T 12-10-2018 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 Gene3D G3DSA:1.25.40.10 249 324 1.3E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 Pfam PF07719 Tetratricopeptide repeat 100 131 1.8E-8 T 12-10-2018 IPR013105 Tetratricopeptide repeat 2 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 SMART SM00028 31 64 1.3 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 SMART SM00028 199 232 290.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 SMART SM00028 386 419 190.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 SMART SM00028 263 296 93.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 SMART SM00028 99 132 1.2E-5 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 SMART SM00028 65 98 1.1 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 SMART SM00028 420 453 0.08 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 SUPERFAMILY SSF48452 252 457 4.16E-17 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 Pfam PF07721 Tetratricopeptide repeat 353 377 0.018 T 12-10-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 TSC_c22120 ea3d356c3572e8fce91499aacb25fb62 460 Gene3D G3DSA:1.25.40.10 326 393 1.0E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c24020 a1f4c81dd9f4931ade7a8172ca04dd1d 230 SUPERFAMILY SSF51161 4 162 1.52E-45 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily TSC_c24020 a1f4c81dd9f4931ade7a8172ca04dd1d 230 Gene3D G3DSA:2.160.10.10 2 164 3.1E-55 T 12-10-2018 TSC_c24020 a1f4c81dd9f4931ade7a8172ca04dd1d 230 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 121 1.2E-8 T 12-10-2018 IPR001451 Hexapeptide repeat TSC_c24020 a1f4c81dd9f4931ade7a8172ca04dd1d 230 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 13 45 7.5E-4 T 12-10-2018 IPR001451 Hexapeptide repeat TSC_c03370 c1afab813ed0af23df88ca0d7d6f03a6 164 SUPERFAMILY SSF141259 2 69 1.06E-11 T 12-10-2018 IPR036101 CarD-like/TRCF domain superfamily TSC_c03370 c1afab813ed0af23df88ca0d7d6f03a6 164 Pfam PF02559 CarD-like/TRCF domain 4 108 3.9E-13 T 12-10-2018 IPR003711 CarD-like/TRCF domain TSC_c03370 c1afab813ed0af23df88ca0d7d6f03a6 164 SMART SM01058 3 113 1.4E-20 T 12-10-2018 IPR003711 CarD-like/TRCF domain TSC_c03370 c1afab813ed0af23df88ca0d7d6f03a6 164 Gene3D G3DSA:1.20.58.1290 62 160 1.4E-38 T 12-10-2018 TSC_c03370 c1afab813ed0af23df88ca0d7d6f03a6 164 Gene3D G3DSA:2.30.30.840 1 61 2.0E-18 T 12-10-2018 TSC_c21890 509a8ac1a309dd0226f350a8ba48c400 203 Pfam PF01914 MarC family integral membrane protein 3 203 1.7E-59 T 12-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TSC_c21890 509a8ac1a309dd0226f350a8ba48c400 203 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 2 199 6.0E-58 T 12-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 TSC_c09420 0c877a3596680ac468b8741e1203f761 132 Pfam PF03061 Thioesterase superfamily 17 100 7.4E-17 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TSC_c09420 0c877a3596680ac468b8741e1203f761 132 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 6 113 1.2E-23 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 TSC_c09420 0c877a3596680ac468b8741e1203f761 132 Gene3D G3DSA:3.10.129.10 1 132 1.1E-39 T 12-10-2018 TSC_c09420 0c877a3596680ac468b8741e1203f761 132 SUPERFAMILY SSF54637 4 126 7.63E-37 T 12-10-2018 IPR029069 HotDog domain superfamily TSC_c09420 0c877a3596680ac468b8741e1203f761 132 PIRSF PIRSF003230 1 131 3.8E-31 T 12-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 TSC_c06140 1a6257bba0661787850f0a716505b263 238 Pfam PF04029 2-phosphosulpholactate phosphatase 15 211 1.3E-24 T 12-10-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 TSC_c06140 1a6257bba0661787850f0a716505b263 238 SUPERFAMILY SSF142823 11 213 9.94E-25 T 12-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 TSC_c06140 1a6257bba0661787850f0a716505b263 238 Gene3D G3DSA:3.90.1560.10 3 217 5.3E-24 T 12-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 TSC_c06770 549a22ec9d39278d71719b7ebb974eab 238 Pfam PF00230 Major intrinsic protein 6 233 4.8E-32 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TSC_c06770 549a22ec9d39278d71719b7ebb974eab 238 PRINTS PR00783 Major intrinsic protein family signature 6 25 2.0E-34 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TSC_c06770 549a22ec9d39278d71719b7ebb974eab 238 PRINTS PR00783 Major intrinsic protein family signature 49 73 2.0E-34 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TSC_c06770 549a22ec9d39278d71719b7ebb974eab 238 PRINTS PR00783 Major intrinsic protein family signature 145 163 2.0E-34 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TSC_c06770 549a22ec9d39278d71719b7ebb974eab 238 PRINTS PR00783 Major intrinsic protein family signature 172 194 2.0E-34 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TSC_c06770 549a22ec9d39278d71719b7ebb974eab 238 PRINTS PR00783 Major intrinsic protein family signature 216 236 2.0E-34 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TSC_c06770 549a22ec9d39278d71719b7ebb974eab 238 PRINTS PR00783 Major intrinsic protein family signature 86 105 2.0E-34 T 12-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 TSC_c06770 549a22ec9d39278d71719b7ebb974eab 238 Gene3D G3DSA:1.20.1080.10 1 237 1.9E-53 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 TSC_c06770 549a22ec9d39278d71719b7ebb974eab 238 SUPERFAMILY SSF81338 6 235 7.19E-46 T 12-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 TSC_c06770 549a22ec9d39278d71719b7ebb974eab 238 ProSitePatterns PS00221 MIP family signature. 67 75 - T 12-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 TSC_c23450 4f05393e4ba5b99e2f3a6be37928eb98 562 SUPERFAMILY SSF55486 42 560 2.41E-82 T 12-10-2018 TSC_c23450 4f05393e4ba5b99e2f3a6be37928eb98 562 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 4 559 2.2E-187 T 12-10-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 TSC_c23450 4f05393e4ba5b99e2f3a6be37928eb98 562 Pfam PF08439 Oligopeptidase F 104 158 1.4E-5 T 12-10-2018 IPR013647 Oligopeptidase F, N-terminal domain TSC_c23450 4f05393e4ba5b99e2f3a6be37928eb98 562 Gene3D G3DSA:1.10.1370.30 14 561 6.0E-110 T 12-10-2018 TSC_c23450 4f05393e4ba5b99e2f3a6be37928eb98 562 Pfam PF01432 Peptidase family M3 179 547 7.2E-27 T 12-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 TSC_c02310 0787b054f582adc2b1b22660f0e7a0ef 289 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 159 280 3.1E-40 T 12-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 TSC_c02310 0787b054f582adc2b1b22660f0e7a0ef 289 SUPERFAMILY SSF51735 3 157 4.16E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c02310 0787b054f582adc2b1b22660f0e7a0ef 289 Gene3D G3DSA:1.10.1040.10 158 289 4.9E-30 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSC_c02310 0787b054f582adc2b1b22660f0e7a0ef 289 Gene3D G3DSA:3.40.50.720 2 157 3.2E-53 T 12-10-2018 TSC_c02310 0787b054f582adc2b1b22660f0e7a0ef 289 SUPERFAMILY SSF48179 158 288 2.95E-28 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSC_c02310 0787b054f582adc2b1b22660f0e7a0ef 289 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 12-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 TSC_c02310 0787b054f582adc2b1b22660f0e7a0ef 289 PIRSF PIRSF000103 1 288 1.5E-57 T 12-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 TSC_c02310 0787b054f582adc2b1b22660f0e7a0ef 289 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 156 2.1E-39 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TSC_c16700 2df68aabffdaf341e2d647b742188412 140 SUPERFAMILY SSF55718 2 136 1.77E-32 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily TSC_c16700 2df68aabffdaf341e2d647b742188412 140 Pfam PF02036 SCP-2 sterol transfer family 20 119 2.2E-8 T 12-10-2018 IPR003033 SCP2 sterol-binding domain TSC_c16700 2df68aabffdaf341e2d647b742188412 140 Gene3D G3DSA:3.30.1050.10 3 132 5.2E-41 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily TSC_c10850 dc406579a441468b46f10d01ce436a73 320 Gene3D G3DSA:1.10.3720.10 52 317 8.3E-75 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c10850 dc406579a441468b46f10d01ce436a73 320 SUPERFAMILY SSF161098 56 306 2.75E-64 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c10850 dc406579a441468b46f10d01ce436a73 320 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 310 4.1E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c24150 507f65c32242262c0cb4c24d7abf640f 400 SUPERFAMILY SSF89796 1 392 4.06E-147 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily TSC_c24150 507f65c32242262c0cb4c24d7abf640f 400 Gene3D G3DSA:3.30.1540.10 230 319 2.7E-142 T 12-10-2018 TSC_c24150 507f65c32242262c0cb4c24d7abf640f 400 Pfam PF02515 CoA-transferase family III 4 369 8.8E-136 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 TSC_c24150 507f65c32242262c0cb4c24d7abf640f 400 Gene3D G3DSA:3.40.50.10540 3 386 2.7E-142 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily TSC_c21770 566e766bf5a76293d3f5ae1c84ca6323 75 Gene3D G3DSA:1.10.10.10 6 74 7.2E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c21770 566e766bf5a76293d3f5ae1c84ca6323 75 SUPERFAMILY SSF46689 2 71 8.78E-24 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSC_c21770 566e766bf5a76293d3f5ae1c84ca6323 75 Pfam PF04255 Protein of unknown function (DUF433) 7 62 2.4E-24 T 12-10-2018 IPR007367 Protein of unknown function DUF433 TSC_c20170 cbe162c12f8ab2be69f41c87e84fdf38 257 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 77 99 - T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TSC_c20170 cbe162c12f8ab2be69f41c87e84fdf38 257 Gene3D G3DSA:1.20.120.1760 6 174 2.8E-21 T 12-10-2018 TSC_c20170 cbe162c12f8ab2be69f41c87e84fdf38 257 Pfam PF01066 CDP-alcohol phosphatidyltransferase 37 97 8.3E-7 T 12-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 TSC_c00110 60f17bb65b5b2b4a69871f145d0dbbd7 181 Pfam PF01936 NYN domain 3 160 4.1E-31 T 12-10-2018 IPR021139 NYN domain, limkain-b1-type TSC_c00110 60f17bb65b5b2b4a69871f145d0dbbd7 181 Gene3D G3DSA:3.40.50.1010 1 163 1.1E-40 T 12-10-2018 TSC_c05080 d74dd183c9f661320e0e2ace82c910f6 322 Pfam PF02653 Branched-chain amino acid transport system / permease component 13 306 5.6E-49 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSC_c18810 044e881a7bc382e37794b863ec007313 397 Gene3D G3DSA:1.10.3720.10 133 395 5.2E-71 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c18810 044e881a7bc382e37794b863ec007313 397 SUPERFAMILY SSF161098 137 384 3.01E-56 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c18810 044e881a7bc382e37794b863ec007313 397 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 165 394 5.9E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c15740 7eef0807760b1318e4b8333469da8bf5 190 Gene3D G3DSA:1.10.260.40 1 62 3.2E-9 T 12-10-2018 TSC_c15740 7eef0807760b1318e4b8333469da8bf5 190 SUPERFAMILY SSF47413 1 65 5.36E-9 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSC_c15740 7eef0807760b1318e4b8333469da8bf5 190 SMART SM00530 4 62 7.8E-5 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSC_c15740 7eef0807760b1318e4b8333469da8bf5 190 Pfam PF13560 Helix-turn-helix domain 2 61 9.3E-9 T 12-10-2018 TSC_c18260 d686cfc109efb4d5b910ad1786b22bbc 139 SUPERFAMILY SSF88723 1 131 7.01E-16 T 12-10-2018 IPR029060 PIN-like domain superfamily TSC_c18260 d686cfc109efb4d5b910ad1786b22bbc 139 Gene3D G3DSA:3.40.50.1010 1 137 2.0E-14 T 12-10-2018 TSC_c18260 d686cfc109efb4d5b910ad1786b22bbc 139 Pfam PF01850 PIN domain 4 132 2.1E-10 T 12-10-2018 IPR002716 PIN domain TSC_c21930 7310eb0e5fbea75bbf5e0fdd65184268 220 Hamap MF_00328 Guanylate kinase [gmk]. 1 183 35.597 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 TSC_c21930 7310eb0e5fbea75bbf5e0fdd65184268 220 Gene3D G3DSA:3.40.50.300 7 179 1.9E-65 T 12-10-2018 TSC_c21930 7310eb0e5fbea75bbf5e0fdd65184268 220 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 3 180 8.3E-70 T 12-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 TSC_c21930 7310eb0e5fbea75bbf5e0fdd65184268 220 ProSitePatterns PS00856 Guanylate kinase-like signature. 36 53 - T 12-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 TSC_c21930 7310eb0e5fbea75bbf5e0fdd65184268 220 Pfam PF00625 Guanylate kinase 4 181 6.0E-45 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit TSC_c21930 7310eb0e5fbea75bbf5e0fdd65184268 220 SUPERFAMILY SSF52540 3 186 4.31E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c21930 7310eb0e5fbea75bbf5e0fdd65184268 220 Gene3D G3DSA:3.30.63.10 33 92 1.9E-65 T 12-10-2018 TSC_c21930 7310eb0e5fbea75bbf5e0fdd65184268 220 SMART SM00072 2 183 2.2E-71 T 12-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit TSC_c04040 074f8e60980ecd4b70e37d0069acedeb 337 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 16 326 2.0E-52 T 12-10-2018 IPR003770 Endolytic murein transglycosylase TSC_c04040 074f8e60980ecd4b70e37d0069acedeb 337 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 14 336 29.115 T 12-10-2018 IPR003770 Endolytic murein transglycosylase TSC_c04040 074f8e60980ecd4b70e37d0069acedeb 337 Gene3D G3DSA:1.10.8.1150 35 104 2.4E-9 T 12-10-2018 TSC_c04040 074f8e60980ecd4b70e37d0069acedeb 337 Pfam PF02618 YceG-like family 40 327 4.2E-67 T 12-10-2018 IPR003770 Endolytic murein transglycosylase TSC_c08160 b9d7136519804b84595bdd4897cf5827 965 Gene3D G3DSA:3.40.50.300 250 427 2.6E-46 T 12-10-2018 TSC_c08160 b9d7136519804b84595bdd4897cf5827 965 Pfam PF04851 Type III restriction enzyme, res subunit 250 408 5.4E-22 T 12-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 TSC_c08160 b9d7136519804b84595bdd4897cf5827 965 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 10 659 2.4E-145 T 12-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 TSC_c08160 b9d7136519804b84595bdd4897cf5827 965 SUPERFAMILY SSF52540 203 463 2.93E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c08160 b9d7136519804b84595bdd4897cf5827 965 SUPERFAMILY SSF52540 275 646 1.38E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c08160 b9d7136519804b84595bdd4897cf5827 965 SMART SM00487 247 436 7.0E-20 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSC_c08160 b9d7136519804b84595bdd4897cf5827 965 Gene3D G3DSA:3.40.50.300 433 669 3.7E-37 T 12-10-2018 TSC_c08160 b9d7136519804b84595bdd4897cf5827 965 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 3 193 1.2E-31 T 12-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 TSC_c08160 b9d7136519804b84595bdd4897cf5827 965 Gene3D G3DSA:3.90.1570.50 76 244 1.5E-22 T 12-10-2018 TSC_c19310 3c7b7cacac8678e9831e446bd66a1d0f 307 SUPERFAMILY SSF53271 86 279 8.88E-41 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TSC_c19310 3c7b7cacac8678e9831e446bd66a1d0f 307 Gene3D G3DSA:3.40.50.2020 6 295 1.6E-109 T 12-10-2018 TSC_c19310 3c7b7cacac8678e9831e446bd66a1d0f 307 SMART SM01400 3 119 9.9E-81 T 12-10-2018 TSC_c19310 3c7b7cacac8678e9831e446bd66a1d0f 307 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 127 142 - T 12-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 TSC_c19310 3c7b7cacac8678e9831e446bd66a1d0f 307 Pfam PF00156 Phosphoribosyl transferase domain 148 240 1.0E-11 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSC_c19310 3c7b7cacac8678e9831e446bd66a1d0f 307 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 3 119 5.4E-48 T 12-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TSC_c19310 3c7b7cacac8678e9831e446bd66a1d0f 307 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 4 306 2.2E-106 T 12-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 TSC_c19310 3c7b7cacac8678e9831e446bd66a1d0f 307 SUPERFAMILY SSF53271 3 156 4.59E-55 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TSC_c19310 3c7b7cacac8678e9831e446bd66a1d0f 307 Gene3D G3DSA:3.40.50.2020 146 284 1.6E-109 T 12-10-2018 TSC_c08080 4f755cd601e5d3bd74333e2ce290f838 425 TIGRFAM TIGR00416 sms: DNA repair protein RadA 2 413 1.8E-137 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 TSC_c08080 4f755cd601e5d3bd74333e2ce290f838 425 Pfam PF13481 AAA domain 75 207 3.9E-13 T 12-10-2018 TSC_c08080 4f755cd601e5d3bd74333e2ce290f838 425 SUPERFAMILY SSF54211 238 412 7.59E-31 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c08080 4f755cd601e5d3bd74333e2ce290f838 425 Hamap MF_01498 DNA repair protein RadA [radA]. 19 424 40.767 T 12-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 TSC_c08080 4f755cd601e5d3bd74333e2ce290f838 425 PRINTS PR01874 DNA repair protein radA signature 8 32 7.7E-76 T 12-10-2018 TSC_c08080 4f755cd601e5d3bd74333e2ce290f838 425 PRINTS PR01874 DNA repair protein radA signature 75 103 7.7E-76 T 12-10-2018 TSC_c08080 4f755cd601e5d3bd74333e2ce290f838 425 PRINTS PR01874 DNA repair protein radA signature 159 183 7.7E-76 T 12-10-2018 TSC_c08080 4f755cd601e5d3bd74333e2ce290f838 425 PRINTS PR01874 DNA repair protein radA signature 198 226 7.7E-76 T 12-10-2018 TSC_c08080 4f755cd601e5d3bd74333e2ce290f838 425 PRINTS PR01874 DNA repair protein radA signature 114 131 7.7E-76 T 12-10-2018 TSC_c08080 4f755cd601e5d3bd74333e2ce290f838 425 PRINTS PR01874 DNA repair protein radA signature 305 328 7.7E-76 T 12-10-2018 TSC_c08080 4f755cd601e5d3bd74333e2ce290f838 425 PRINTS PR01874 DNA repair protein radA signature 231 257 7.7E-76 T 12-10-2018 TSC_c08080 4f755cd601e5d3bd74333e2ce290f838 425 Pfam PF13541 Subunit ChlI of Mg-chelatase 329 410 1.6E-8 T 12-10-2018 TSC_c08080 4f755cd601e5d3bd74333e2ce290f838 425 SMART SM00382 83 229 1.3E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c08080 4f755cd601e5d3bd74333e2ce290f838 425 Gene3D G3DSA:3.30.230.10 281 422 4.6E-13 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSC_c08080 4f755cd601e5d3bd74333e2ce290f838 425 Gene3D G3DSA:3.40.50.300 55 266 7.6E-37 T 12-10-2018 TSC_c08080 4f755cd601e5d3bd74333e2ce290f838 425 SUPERFAMILY SSF52540 62 276 5.43E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c09190 1f06e0c362e8f04ee4d2be902cc91e7a 383 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 9 107 1.5E-20 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TSC_c09190 1f06e0c362e8f04ee4d2be902cc91e7a 383 Gene3D G3DSA:3.40.430.10 149 382 1.3E-61 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TSC_c09190 1f06e0c362e8f04ee4d2be902cc91e7a 383 SUPERFAMILY SSF53597 152 380 2.13E-52 T 12-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 TSC_c09190 1f06e0c362e8f04ee4d2be902cc91e7a 383 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 153 380 1.1E-47 T 12-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 TSC_c09190 1f06e0c362e8f04ee4d2be902cc91e7a 383 Pfam PF01872 RibD C-terminal domain 154 375 4.4E-38 T 12-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 TSC_c09190 1f06e0c362e8f04ee4d2be902cc91e7a 383 Gene3D G3DSA:3.40.140.10 7 148 1.1E-44 T 12-10-2018 TSC_c09190 1f06e0c362e8f04ee4d2be902cc91e7a 383 PIRSF PIRSF006769 7 383 3.1E-129 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 TSC_c09190 1f06e0c362e8f04ee4d2be902cc91e7a 383 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 58 96 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TSC_c09190 1f06e0c362e8f04ee4d2be902cc91e7a 383 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 16 376 9.4E-103 T 12-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 TSC_c09190 1f06e0c362e8f04ee4d2be902cc91e7a 383 SUPERFAMILY SSF53927 11 152 5.31E-46 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TSC_c15730 e37100a847272cb1e1e9e5d36f09e2b6 463 SUPERFAMILY SSF55347 176 392 4.09E-23 T 12-10-2018 TSC_c15730 e37100a847272cb1e1e9e5d36f09e2b6 463 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 54 170 1.5E-20 T 12-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 TSC_c15730 e37100a847272cb1e1e9e5d36f09e2b6 463 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 182 253 5.1E-9 T 12-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 TSC_c15730 e37100a847272cb1e1e9e5d36f09e2b6 463 Gene3D G3DSA:3.40.50.720 52 170 1.3E-26 T 12-10-2018 TSC_c15730 e37100a847272cb1e1e9e5d36f09e2b6 463 SUPERFAMILY SSF51735 54 197 9.4E-36 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c05480 57edc7495cfcca590c7c30528721fdf6 252 SUPERFAMILY SSF142823 14 226 9.94E-56 T 12-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 TSC_c05480 57edc7495cfcca590c7c30528721fdf6 252 Gene3D G3DSA:3.90.1560.10 1 237 2.4E-85 T 12-10-2018 IPR036702 ComB-like superfamily GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 TSC_c05480 57edc7495cfcca590c7c30528721fdf6 252 Pfam PF04029 2-phosphosulpholactate phosphatase 14 225 7.7E-69 T 12-10-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 TSC_c05480 57edc7495cfcca590c7c30528721fdf6 252 Hamap MF_00490 2-phosphosulfolactate phosphatase [comB]. 1 233 26.242 T 12-10-2018 IPR005238 ComB-like GO:0000287|GO:0050532 KEGG: 00680+3.1.3.71 TSC_c22990 19c539155277fd69c76749ca830b9919 375 SMART SM00863 185 227 6.3E-12 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSC_c22990 19c539155277fd69c76749ca830b9919 375 Gene3D G3DSA:2.40.30.130 1 90 4.7E-21 T 12-10-2018 TSC_c22990 19c539155277fd69c76749ca830b9919 375 SUPERFAMILY SSF50447 2 90 1.41E-14 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSC_c22990 19c539155277fd69c76749ca830b9919 375 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 185 227 4.4E-8 T 12-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 TSC_c22990 19c539155277fd69c76749ca830b9919 375 SUPERFAMILY SSF55186 94 234 7.46E-32 T 12-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 TSC_c22990 19c539155277fd69c76749ca830b9919 375 Pfam PF01411 tRNA synthetases class II (A) 17 94 2.4E-12 T 12-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 TSC_c22990 19c539155277fd69c76749ca830b9919 375 Gene3D G3DSA:3.30.980.10 91 244 3.7E-41 T 12-10-2018 TSC_c19450 f2d12c51dcb73b36671838901fd03527 202 Pfam PF03692 Putative zinc- or iron-chelating domain 28 112 1.9E-5 T 12-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein TSC_c01160 bfa35f94f78b6bedd6e6385af7dfe2f9 147 Pfam PF01475 Ferric uptake regulator family 17 138 6.3E-27 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TSC_c01160 bfa35f94f78b6bedd6e6385af7dfe2f9 147 Gene3D G3DSA:3.30.1490.190 89 147 9.4E-16 T 12-10-2018 TSC_c01160 bfa35f94f78b6bedd6e6385af7dfe2f9 147 Gene3D G3DSA:1.10.10.10 4 87 4.2E-19 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c01160 bfa35f94f78b6bedd6e6385af7dfe2f9 147 SUPERFAMILY SSF46785 8 144 3.69E-32 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c22850 77b2a1057007e6494f9101ff6851eae9 496 SUPERFAMILY SSF51905 4 493 7.62E-25 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c22850 77b2a1057007e6494f9101ff6851eae9 496 Gene3D G3DSA:3.90.700.10 413 428 2.9E-15 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c22850 77b2a1057007e6494f9101ff6851eae9 496 Gene3D G3DSA:3.50.50.60 429 489 2.9E-15 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c22850 77b2a1057007e6494f9101ff6851eae9 496 Gene3D G3DSA:3.50.50.60 1 242 1.8E-24 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c22850 77b2a1057007e6494f9101ff6851eae9 496 Pfam PF00890 FAD binding domain 1 477 6.3E-77 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c02360 e6da221c75d313650eb052d48f590c22 462 Gene3D G3DSA:3.30.559.10 223 460 2.8E-86 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TSC_c02360 e6da221c75d313650eb052d48f590c22 462 Pfam PF00364 Biotin-requiring enzyme 3 75 7.9E-17 T 12-10-2018 IPR000089 Biotin/lipoyl attachment TSC_c02360 e6da221c75d313650eb052d48f590c22 462 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TSC_c02360 e6da221c75d313650eb052d48f590c22 462 SUPERFAMILY SSF51230 1 94 8.11E-27 T 12-10-2018 IPR011053 Single hybrid motif TSC_c02360 e6da221c75d313650eb052d48f590c22 462 Gene3D G3DSA:2.40.50.100 1 98 2.0E-26 T 12-10-2018 TSC_c02360 e6da221c75d313650eb052d48f590c22 462 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 231 460 3.0E-86 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 TSC_c02360 e6da221c75d313650eb052d48f590c22 462 SUPERFAMILY SSF47005 148 191 9.94E-11 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TSC_c02360 e6da221c75d313650eb052d48f590c22 462 Gene3D G3DSA:4.10.320.10 152 192 4.0E-19 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TSC_c02360 e6da221c75d313650eb052d48f590c22 462 SUPERFAMILY SSF52777 219 460 4.89E-85 T 12-10-2018 TSC_c02360 e6da221c75d313650eb052d48f590c22 462 Pfam PF02817 e3 binding domain 152 187 1.2E-13 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 TSC_c21620 782a820fed26bf9c383712d2b8325307 224 SMART SM00862 147 221 5.1E-29 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c21620 782a820fed26bf9c383712d2b8325307 224 Gene3D G3DSA:1.10.10.10 125 224 8.7E-32 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c21620 782a820fed26bf9c383712d2b8325307 224 Pfam PF00072 Response regulator receiver domain 6 115 2.3E-28 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c21620 782a820fed26bf9c383712d2b8325307 224 SUPERFAMILY SSF52172 1 172 2.41E-43 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c21620 782a820fed26bf9c383712d2b8325307 224 Gene3D G3DSA:3.40.50.2300 1 124 5.8E-39 T 12-10-2018 TSC_c21620 782a820fed26bf9c383712d2b8325307 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 221 2.1E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c21620 782a820fed26bf9c383712d2b8325307 224 SMART SM00448 4 114 1.5E-42 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c17620 e1baac3b240c7ed4f873a2c388d82741 451 Pfam PF07732 Multicopper oxidase 41 140 1.5E-9 T 12-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 TSC_c17620 e1baac3b240c7ed4f873a2c388d82741 451 SUPERFAMILY SSF49503 15 141 4.51E-25 T 12-10-2018 IPR008972 Cupredoxin TSC_c17620 e1baac3b240c7ed4f873a2c388d82741 451 PRINTS PR00695 Copper containing nitrite reductase signature 45 61 1.4E-9 T 12-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 TSC_c17620 e1baac3b240c7ed4f873a2c388d82741 451 PRINTS PR00695 Copper containing nitrite reductase signature 121 137 1.4E-9 T 12-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 TSC_c17620 e1baac3b240c7ed4f873a2c388d82741 451 PRINTS PR00695 Copper containing nitrite reductase signature 102 117 1.4E-9 T 12-10-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 TSC_c17620 e1baac3b240c7ed4f873a2c388d82741 451 SUPERFAMILY SSF49503 153 286 5.77E-21 T 12-10-2018 IPR008972 Cupredoxin TSC_c17620 e1baac3b240c7ed4f873a2c388d82741 451 Gene3D G3DSA:2.60.40.420 152 292 3.0E-30 T 12-10-2018 IPR008972 Cupredoxin TSC_c17620 e1baac3b240c7ed4f873a2c388d82741 451 Gene3D G3DSA:2.60.40.420 16 138 1.1E-27 T 12-10-2018 IPR008972 Cupredoxin TSC_c17620 e1baac3b240c7ed4f873a2c388d82741 451 Pfam PF13473 Cupredoxin-like domain 348 438 3.4E-6 T 12-10-2018 IPR028096 EfeO-type cupredoxin-like domain TSC_c17620 e1baac3b240c7ed4f873a2c388d82741 451 Gene3D G3DSA:2.60.40.420 337 440 2.0E-20 T 12-10-2018 IPR008972 Cupredoxin TSC_c17620 e1baac3b240c7ed4f873a2c388d82741 451 SUPERFAMILY SSF49503 349 441 3.13E-20 T 12-10-2018 IPR008972 Cupredoxin TSC_c21210 69c02defbc050c2a1b865fc7202a599f 872 Pfam PF13361 UvrD-like helicase C-terminal domain 315 418 8.0E-10 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TSC_c21210 69c02defbc050c2a1b865fc7202a599f 872 Pfam PF12705 PD-(D/E)XK nuclease superfamily 692 852 2.3E-9 T 12-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type TSC_c21210 69c02defbc050c2a1b865fc7202a599f 872 Gene3D G3DSA:3.40.50.300 452 612 2.9E-20 T 12-10-2018 TSC_c21210 69c02defbc050c2a1b865fc7202a599f 872 Pfam PF13361 UvrD-like helicase C-terminal domain 490 599 6.0E-12 T 12-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 TSC_c21210 69c02defbc050c2a1b865fc7202a599f 872 Gene3D G3DSA:3.90.320.10 775 842 1.3E-7 T 12-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal TSC_c21210 69c02defbc050c2a1b865fc7202a599f 872 Gene3D G3DSA:3.40.50.300 155 282 2.1E-25 T 12-10-2018 TSC_c21210 69c02defbc050c2a1b865fc7202a599f 872 SUPERFAMILY SSF52540 3 603 2.86E-89 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c21210 69c02defbc050c2a1b865fc7202a599f 872 Gene3D G3DSA:3.40.50.300 2 123 3.9E-22 T 12-10-2018 TSC_c21210 69c02defbc050c2a1b865fc7202a599f 872 Gene3D G3DSA:3.40.50.300 316 416 2.4E-19 T 12-10-2018 TSC_c21210 69c02defbc050c2a1b865fc7202a599f 872 SUPERFAMILY SSF52980 694 835 4.18E-11 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSC_c21210 69c02defbc050c2a1b865fc7202a599f 872 Pfam PF13245 AAA domain 5 242 1.2E-23 T 12-10-2018 TSC_c17240 01781b62aa1c74ebe21339a5236c055d 317 Pfam PF00762 Ferrochelatase 3 313 4.3E-75 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TSC_c17240 01781b62aa1c74ebe21339a5236c055d 317 Gene3D G3DSA:3.40.50.1400 158 296 5.8E-93 T 12-10-2018 TSC_c17240 01781b62aa1c74ebe21339a5236c055d 317 Hamap MF_00323 Ferrochelatase [hemH]. 1 315 26.6 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TSC_c17240 01781b62aa1c74ebe21339a5236c055d 317 SUPERFAMILY SSF53800 3 313 1.36E-70 T 12-10-2018 TSC_c17240 01781b62aa1c74ebe21339a5236c055d 317 TIGRFAM TIGR00109 hemH: ferrochelatase 2 313 6.8E-60 T 12-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 TSC_c17240 01781b62aa1c74ebe21339a5236c055d 317 Gene3D G3DSA:3.40.50.1400 3 311 5.8E-93 T 12-10-2018 TSC_c04990 6253c7a9f74acde19c2efb8e0bf4cd65 608 SUPERFAMILY SSF90123 25 348 1.57E-85 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSC_c04990 6253c7a9f74acde19c2efb8e0bf4cd65 608 SMART SM00382 393 580 5.6E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c04990 6253c7a9f74acde19c2efb8e0bf4cd65 608 SUPERFAMILY SSF52540 350 605 3.84E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c04990 6253c7a9f74acde19c2efb8e0bf4cd65 608 Pfam PF00664 ABC transporter transmembrane region 38 315 9.3E-58 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSC_c04990 6253c7a9f74acde19c2efb8e0bf4cd65 608 Gene3D G3DSA:3.40.50.300 353 607 1.9E-84 T 12-10-2018 TSC_c04990 6253c7a9f74acde19c2efb8e0bf4cd65 608 Pfam PF00005 ABC transporter 384 534 3.9E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c04990 6253c7a9f74acde19c2efb8e0bf4cd65 608 Gene3D G3DSA:1.20.1560.10 3 348 1.6E-99 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSC_c02510 6e2e06b538f1ca5d4da7845874d0e23a 250 Gene3D G3DSA:3.30.70.1100 124 249 5.3E-54 T 12-10-2018 TSC_c02510 6e2e06b538f1ca5d4da7845874d0e23a 250 SUPERFAMILY SSF54909 6 248 1.29E-80 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TSC_c02510 6e2e06b538f1ca5d4da7845874d0e23a 250 Gene3D G3DSA:3.30.70.1030 1 123 1.7E-39 T 12-10-2018 TSC_c02510 6e2e06b538f1ca5d4da7845874d0e23a 250 Pfam PF06778 Chlorite dismutase 37 238 5.8E-62 T 12-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase TSC_c13370 c243e538adabfac46a76804f5d0cc720 458 Gene3D G3DSA:1.10.3080.10 24 432 8.4E-39 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 TSC_c13370 c243e538adabfac46a76804f5d0cc720 458 SUPERFAMILY SSF81340 20 415 5.36E-45 T 12-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 TSC_c13370 c243e538adabfac46a76804f5d0cc720 458 Pfam PF00654 Voltage gated chloride channel 117 412 4.5E-35 T 12-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 TSC_c11670 b2a7db6bca07d62561d11110cae0fa3c 178 SUPERFAMILY SSF53254 1 145 4.84E-47 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TSC_c11670 b2a7db6bca07d62561d11110cae0fa3c 178 Gene3D G3DSA:3.40.50.1240 1 176 3.6E-52 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TSC_c11670 b2a7db6bca07d62561d11110cae0fa3c 178 SMART SM00855 2 140 2.9E-26 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSC_c11670 b2a7db6bca07d62561d11110cae0fa3c 178 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 144 7.6E-35 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSC_c11670 b2a7db6bca07d62561d11110cae0fa3c 178 PIRSF PIRSF000709 1 97 6.3E-4 T 12-10-2018 TSC_c11670 b2a7db6bca07d62561d11110cae0fa3c 178 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 TSC_c12220 266cfcdf25532a695083a0c01d49efa8 510 Gene3D G3DSA:3.90.700.10 229 320 2.3E-127 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c12220 266cfcdf25532a695083a0c01d49efa8 510 SUPERFAMILY SSF46977 402 493 6.67E-19 T 12-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c12220 266cfcdf25532a695083a0c01d49efa8 510 Gene3D G3DSA:1.20.58.100 399 488 1.0E-18 T 12-10-2018 TSC_c12220 266cfcdf25532a695083a0c01d49efa8 510 Pfam PF00890 FAD binding domain 5 365 8.4E-83 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c12220 266cfcdf25532a695083a0c01d49efa8 510 SUPERFAMILY SSF51905 3 384 9.09E-61 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c12220 266cfcdf25532a695083a0c01d49efa8 510 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.2E-5 T 12-10-2018 TSC_c12220 266cfcdf25532a695083a0c01d49efa8 510 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 350 2.2E-5 T 12-10-2018 TSC_c12220 266cfcdf25532a695083a0c01d49efa8 510 Gene3D G3DSA:3.50.50.60 5 376 2.3E-127 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c12220 266cfcdf25532a695083a0c01d49efa8 510 SUPERFAMILY SSF56425 219 325 4.49E-34 T 12-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c12220 266cfcdf25532a695083a0c01d49efa8 510 Pfam PF02910 Fumarate reductase flavoprotein C-term 403 494 3.2E-14 T 12-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c12220 266cfcdf25532a695083a0c01d49efa8 510 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 8.6E-8 T 12-10-2018 TSC_c12220 266cfcdf25532a695083a0c01d49efa8 510 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 328 350 8.6E-8 T 12-10-2018 TSC_c13820 e4b9f49e39a0803b6c921b02dc55e17d 285 ProSitePatterns PS00380 Rhodanese signature 1. 36 47 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TSC_c13820 e4b9f49e39a0803b6c921b02dc55e17d 285 SMART SM00450 151 278 1.2E-24 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c13820 e4b9f49e39a0803b6c921b02dc55e17d 285 SMART SM00450 10 124 1.9E-20 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c13820 e4b9f49e39a0803b6c921b02dc55e17d 285 ProSitePatterns PS00683 Rhodanese C-terminal signature. 262 272 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TSC_c13820 e4b9f49e39a0803b6c921b02dc55e17d 285 Gene3D G3DSA:3.40.250.10 1 143 7.7E-47 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c13820 e4b9f49e39a0803b6c921b02dc55e17d 285 Pfam PF00581 Rhodanese-like domain 163 273 3.5E-20 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c13820 e4b9f49e39a0803b6c921b02dc55e17d 285 Pfam PF00581 Rhodanese-like domain 11 120 1.3E-16 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c13820 e4b9f49e39a0803b6c921b02dc55e17d 285 SUPERFAMILY SSF52821 160 283 1.96E-40 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c13820 e4b9f49e39a0803b6c921b02dc55e17d 285 SUPERFAMILY SSF52821 3 142 1.26E-41 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c13820 e4b9f49e39a0803b6c921b02dc55e17d 285 Gene3D G3DSA:3.40.250.10 144 285 5.5E-50 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c22440 08ec5bdd24a5abd49bf4e0d3cc6df554 206 ProSitePatterns PS00474 Ribosomal protein L3 signature. 96 119 - T 12-10-2018 IPR019926 Ribosomal protein L3, conserved site TSC_c22440 08ec5bdd24a5abd49bf4e0d3cc6df554 206 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 202 38.445 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22440 08ec5bdd24a5abd49bf4e0d3cc6df554 206 SUPERFAMILY SSF50447 1 203 7.24E-76 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSC_c22440 08ec5bdd24a5abd49bf4e0d3cc6df554 206 Pfam PF00297 Ribosomal protein L3 91 176 1.9E-13 T 12-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22440 08ec5bdd24a5abd49bf4e0d3cc6df554 206 Gene3D G3DSA:2.40.50.620 30 88 1.1E-16 T 12-10-2018 TSC_c22440 08ec5bdd24a5abd49bf4e0d3cc6df554 206 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 3 199 5.4E-84 T 12-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22440 08ec5bdd24a5abd49bf4e0d3cc6df554 206 Gene3D G3DSA:2.40.30.10 126 205 1.3E-17 T 12-10-2018 TSC_c21460 5a3f55313edf6cde08f8c60a1483dca2 209 Gene3D G3DSA:3.40.50.1000 1 204 2.6E-32 T 12-10-2018 IPR023214 HAD superfamily TSC_c21460 5a3f55313edf6cde08f8c60a1483dca2 209 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 105 197 5.7E-13 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c21460 5a3f55313edf6cde08f8c60a1483dca2 209 Pfam PF13419 Haloacid dehalogenase-like hydrolase 75 197 4.7E-15 T 12-10-2018 TSC_c21460 5a3f55313edf6cde08f8c60a1483dca2 209 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 144 160 8.9E-14 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c21460 5a3f55313edf6cde08f8c60a1483dca2 209 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 8.9E-14 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c21460 5a3f55313edf6cde08f8c60a1483dca2 209 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 114 127 8.9E-14 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c21460 5a3f55313edf6cde08f8c60a1483dca2 209 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 162 182 8.9E-14 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c21460 5a3f55313edf6cde08f8c60a1483dca2 209 SUPERFAMILY SSF56784 2 199 9.19E-32 T 12-10-2018 IPR036412 HAD-like superfamily TSC_p800120 ccaa50b625cb9d50f07c7ba350e319e6 354 Pfam PF00472 RF-1 domain 208 316 2.1E-40 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TSC_p800120 ccaa50b625cb9d50f07c7ba350e319e6 354 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 223 239 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TSC_p800120 ccaa50b625cb9d50f07c7ba350e319e6 354 SMART SM00937 59 174 1.7E-50 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 TSC_p800120 ccaa50b625cb9d50f07c7ba350e319e6 354 Pfam PF03462 PCRF domain 8 199 1.8E-69 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 TSC_p800120 ccaa50b625cb9d50f07c7ba350e319e6 354 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 352 37.325 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 TSC_p800120 ccaa50b625cb9d50f07c7ba350e319e6 354 Gene3D G3DSA:3.30.160.20 206 286 1.7E-94 T 12-10-2018 TSC_p800120 ccaa50b625cb9d50f07c7ba350e319e6 354 SUPERFAMILY SSF75620 8 348 1.44E-129 T 12-10-2018 TSC_p800120 ccaa50b625cb9d50f07c7ba350e319e6 354 Gene3D G3DSA:3.30.70.1660 108 335 1.7E-94 T 12-10-2018 TSC_p800120 ccaa50b625cb9d50f07c7ba350e319e6 354 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 1 353 9.7E-142 T 12-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 TSC_c14570 c2eb5a26b20a8523346d1fd28852033a 166 SUPERFAMILY SSF53098 1 160 4.55E-39 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c14570 c2eb5a26b20a8523346d1fd28852033a 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 110 129 3.3E-25 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TSC_c14570 c2eb5a26b20a8523346d1fd28852033a 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 3.3E-25 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TSC_c14570 c2eb5a26b20a8523346d1fd28852033a 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 86 102 3.3E-25 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TSC_c14570 c2eb5a26b20a8523346d1fd28852033a 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 64 80 3.3E-25 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TSC_c14570 c2eb5a26b20a8523346d1fd28852033a 166 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 142 154 3.3E-25 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TSC_c14570 c2eb5a26b20a8523346d1fd28852033a 166 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 159 6.8E-31 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TSC_c14570 c2eb5a26b20a8523346d1fd28852033a 166 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 154 1.2E-38 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TSC_c14570 c2eb5a26b20a8523346d1fd28852033a 166 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 157 40.942 T 12-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 TSC_c14570 c2eb5a26b20a8523346d1fd28852033a 166 Gene3D G3DSA:3.30.420.10 1 166 1.1E-48 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSC_c04630 30d8641524903edbb4217b878503c55f 325 Pfam PF06463 Molybdenum Cofactor Synthesis C 183 307 1.3E-26 T 12-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSC_c04630 30d8641524903edbb4217b878503c55f 325 Pfam PF04055 Radical SAM superfamily 16 175 5.4E-31 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSC_c04630 30d8641524903edbb4217b878503c55f 325 Gene3D G3DSA:3.20.20.70 1 325 2.5E-82 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c04630 30d8641524903edbb4217b878503c55f 325 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 3 325 6.4E-104 T 12-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSC_c04630 30d8641524903edbb4217b878503c55f 325 Pfam PF13353 4Fe-4S single cluster domain 21 121 7.6E-6 T 12-10-2018 TSC_c04630 30d8641524903edbb4217b878503c55f 325 SMART SM00729 12 216 3.7E-14 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSC_c04630 30d8641524903edbb4217b878503c55f 325 SUPERFAMILY SSF102114 3 276 8.37E-69 T 12-10-2018 TSC_c03190 cec3eea2d07ab36d5b4c9bdfab7011b6 424 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 337 408 5.3E-22 T 12-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c03190 cec3eea2d07ab36d5b4c9bdfab7011b6 424 Gene3D G3DSA:1.20.970.10 1 67 7.9E-22 T 12-10-2018 TSC_c03190 cec3eea2d07ab36d5b4c9bdfab7011b6 424 SUPERFAMILY SSF54680 329 413 1.44E-21 T 12-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c03190 cec3eea2d07ab36d5b4c9bdfab7011b6 424 SUPERFAMILY SSF52418 76 321 2.62E-81 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c03190 cec3eea2d07ab36d5b4c9bdfab7011b6 424 PIRSF PIRSF000478 1 420 2.7E-147 T 12-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c03190 cec3eea2d07ab36d5b4c9bdfab7011b6 424 Gene3D G3DSA:3.40.1030.10 78 323 1.9E-140 T 12-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c03190 cec3eea2d07ab36d5b4c9bdfab7011b6 424 Pfam PF00591 Glycosyl transferase family, a/b domain 77 284 2.6E-33 T 12-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c03190 cec3eea2d07ab36d5b4c9bdfab7011b6 424 SMART SM00941 337 410 3.8E-25 T 12-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c03190 cec3eea2d07ab36d5b4c9bdfab7011b6 424 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 109 124 - T 12-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c03190 cec3eea2d07ab36d5b4c9bdfab7011b6 424 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 66 1.5E-15 T 12-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c03190 cec3eea2d07ab36d5b4c9bdfab7011b6 424 Gene3D G3DSA:3.90.1170.30 324 408 1.9E-140 T 12-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c03190 cec3eea2d07ab36d5b4c9bdfab7011b6 424 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 4 409 2.3E-160 T 12-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c03190 cec3eea2d07ab36d5b4c9bdfab7011b6 424 SUPERFAMILY SSF47648 1 69 1.7E-15 T 12-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c07200 3341b018c99ce58b6ee8ec6263806525 359 Pfam PF02153 Prephenate dehydrogenase 20 260 2.6E-53 T 12-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 TSC_c07200 3341b018c99ce58b6ee8ec6263806525 359 Pfam PF01842 ACT domain 294 334 2.9E-9 T 12-10-2018 IPR002912 ACT domain TSC_c07200 3341b018c99ce58b6ee8ec6263806525 359 Gene3D G3DSA:3.40.50.720 6 177 5.5E-48 T 12-10-2018 TSC_c07200 3341b018c99ce58b6ee8ec6263806525 359 SUPERFAMILY SSF55021 289 352 3.36E-10 T 12-10-2018 TSC_c07200 3341b018c99ce58b6ee8ec6263806525 359 SUPERFAMILY SSF51735 7 168 6.97E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c07200 3341b018c99ce58b6ee8ec6263806525 359 Gene3D G3DSA:1.10.3660.10 178 281 1.2E-27 T 12-10-2018 TSC_c07200 3341b018c99ce58b6ee8ec6263806525 359 Gene3D G3DSA:3.30.70.260 292 356 2.2E-10 T 12-10-2018 TSC_c07200 3341b018c99ce58b6ee8ec6263806525 359 SUPERFAMILY SSF48179 174 280 2.72E-26 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSC_c06540 23ddfe647e5ab577448b8315f1988269 124 Pfam PF01042 Endoribonuclease L-PSP 7 122 1.1E-43 T 12-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 TSC_c06540 23ddfe647e5ab577448b8315f1988269 124 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 2 122 8.4E-51 T 12-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 TSC_c06540 23ddfe647e5ab577448b8315f1988269 124 Gene3D G3DSA:3.30.1330.40 1 124 3.2E-58 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSC_c06540 23ddfe647e5ab577448b8315f1988269 124 SUPERFAMILY SSF55298 3 123 1.41E-48 T 12-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 TSC_c13340 2c53ea01933f79210fb94feaf6d894a1 369 Gene3D G3DSA:3.30.390.10 7 350 1.1E-141 T 12-10-2018 IPR029017 Enolase-like, N-terminal TSC_c13340 2c53ea01933f79210fb94feaf6d894a1 369 SMART SM00922 142 234 1.1E-18 T 12-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal TSC_c13340 2c53ea01933f79210fb94feaf6d894a1 369 SUPERFAMILY SSF54826 1 125 7.37E-33 T 12-10-2018 TSC_c13340 2c53ea01933f79210fb94feaf6d894a1 369 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 12 330 9.1E-104 T 12-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 TSC_c13340 2c53ea01933f79210fb94feaf6d894a1 369 Gene3D G3DSA:3.20.20.120 117 346 1.1E-141 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSC_c13340 2c53ea01933f79210fb94feaf6d894a1 369 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 18 124 5.1E-11 T 12-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain TSC_c13340 2c53ea01933f79210fb94feaf6d894a1 369 Pfam PF13378 Enolase C-terminal domain-like 148 352 7.4E-41 T 12-10-2018 IPR029065 Enolase C-terminal domain-like TSC_c13340 2c53ea01933f79210fb94feaf6d894a1 369 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 1 359 41.521 T 12-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 TSC_c13340 2c53ea01933f79210fb94feaf6d894a1 369 SUPERFAMILY SSF51604 113 363 6.29E-63 T 12-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily TSC_c06320 9f5db9162c4cde17855d7171e85ebd7f 310 Gene3D G3DSA:3.90.226.10 50 248 1.4E-67 T 12-10-2018 TSC_c06320 9f5db9162c4cde17855d7171e85ebd7f 310 Pfam PF01343 Peptidase family S49 105 255 2.4E-46 T 12-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 TSC_c06320 9f5db9162c4cde17855d7171e85ebd7f 310 Gene3D G3DSA:3.40.1750.20 145 211 1.4E-67 T 12-10-2018 TSC_c06320 9f5db9162c4cde17855d7171e85ebd7f 310 SUPERFAMILY SSF52096 36 240 1.34E-36 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSC_c06320 9f5db9162c4cde17855d7171e85ebd7f 310 TIGRFAM TIGR00706 SppA_dom: signal peptide peptidase SppA, 36K type 50 254 1.9E-61 T 12-10-2018 IPR004635 Peptidase S49, SppA GO:0006508|GO:0008233 TSC_c03750 8c1d8ba3ed3e3b1de1e4bc807a719680 129 SUPERFAMILY SSF103247 6 128 2.62E-35 T 12-10-2018 IPR035923 TT1751-like domain superfamily TSC_c03750 8c1d8ba3ed3e3b1de1e4bc807a719680 129 PIRSF PIRSF021774 1 129 7.8E-40 T 12-10-2018 IPR016796 Uncharacterised conserved protein UCP021774 TSC_c03750 8c1d8ba3ed3e3b1de1e4bc807a719680 129 Gene3D G3DSA:3.30.310.70 1 129 6.1E-51 T 12-10-2018 IPR035923 TT1751-like domain superfamily TSC_c03750 8c1d8ba3ed3e3b1de1e4bc807a719680 129 Pfam PF03625 Domain of unknown function DUF302 34 96 3.5E-23 T 12-10-2018 IPR005180 Domain of unknown function DUF302 TSC_c14380 a7daeeb58ffc3e2e0311404694aa32ca 235 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 218 231 - T 12-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TSC_c14380 a7daeeb58ffc3e2e0311404694aa32ca 235 Hamap MF_00124 Thymidine kinase [tdk]. 51 234 36.704 T 12-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TSC_c14380 a7daeeb58ffc3e2e0311404694aa32ca 235 SUPERFAMILY SSF57716 186 233 5.23E-15 T 12-10-2018 TSC_c14380 a7daeeb58ffc3e2e0311404694aa32ca 235 Pfam PF00265 Thymidine kinase 52 231 9.3E-51 T 12-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TSC_c14380 a7daeeb58ffc3e2e0311404694aa32ca 235 SUPERFAMILY SSF52540 52 186 3.98E-40 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c14380 a7daeeb58ffc3e2e0311404694aa32ca 235 Gene3D G3DSA:3.30.60.20 186 235 1.6E-24 T 12-10-2018 TSC_c14380 a7daeeb58ffc3e2e0311404694aa32ca 235 Gene3D G3DSA:3.40.50.300 45 185 8.5E-54 T 12-10-2018 TSC_c14380 a7daeeb58ffc3e2e0311404694aa32ca 235 PIRSF PIRSF035805 49 234 1.4E-62 T 12-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 TSC_c21280 b715fa098022ca90529a1c46534153a1 251 Gene3D G3DSA:3.60.40.10 1 251 1.6E-53 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSC_c21280 b715fa098022ca90529a1c46534153a1 251 SUPERFAMILY SSF81606 6 250 6.28E-51 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSC_c21280 b715fa098022ca90529a1c46534153a1 251 SMART SM00332 1 248 1.4E-11 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSC_c21280 b715fa098022ca90529a1c46534153a1 251 SMART SM00331 12 250 5.6E-21 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSC_c21280 b715fa098022ca90529a1c46534153a1 251 Pfam PF13672 Protein phosphatase 2C 13 217 1.3E-16 T 12-10-2018 TSC_c22370 240338d025bd5c28a2abbee31e5e437c 141 PRINTS PR00060 Ribosomal protein L16 signature 88 117 2.9E-35 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22370 240338d025bd5c28a2abbee31e5e437c 141 PRINTS PR00060 Ribosomal protein L16 signature 24 36 2.9E-35 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22370 240338d025bd5c28a2abbee31e5e437c 141 PRINTS PR00060 Ribosomal protein L16 signature 42 53 2.9E-35 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22370 240338d025bd5c28a2abbee31e5e437c 141 PRINTS PR00060 Ribosomal protein L16 signature 58 87 2.9E-35 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22370 240338d025bd5c28a2abbee31e5e437c 141 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.863 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22370 240338d025bd5c28a2abbee31e5e437c 141 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 2.9E-60 T 12-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22370 240338d025bd5c28a2abbee31e5e437c 141 SUPERFAMILY SSF54686 1 138 9.42E-57 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TSC_c22370 240338d025bd5c28a2abbee31e5e437c 141 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 1.4E-49 T 12-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 TSC_c22370 240338d025bd5c28a2abbee31e5e437c 141 Gene3D G3DSA:3.90.1170.10 1 141 8.5E-54 T 12-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 TSC_c18700 15077d77c41569ea902a50cda14d8527 486 Gene3D G3DSA:3.90.190.20 327 479 1.6E-45 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSC_c18700 15077d77c41569ea902a50cda14d8527 486 Pfam PF08245 Mur ligase middle domain 108 303 3.8E-35 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TSC_c18700 15077d77c41569ea902a50cda14d8527 486 Pfam PF01225 Mur ligase family, catalytic domain 20 95 4.7E-7 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TSC_c18700 15077d77c41569ea902a50cda14d8527 486 SUPERFAMILY SSF53623 72 337 1.49E-50 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSC_c18700 15077d77c41569ea902a50cda14d8527 486 Gene3D G3DSA:3.40.1190.10 99 326 3.1E-61 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSC_c18700 15077d77c41569ea902a50cda14d8527 486 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 475 28.145 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 TSC_c18700 15077d77c41569ea902a50cda14d8527 486 SUPERFAMILY SSF53244 323 476 1.7E-35 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSC_c18700 15077d77c41569ea902a50cda14d8527 486 Pfam PF02875 Mur ligase family, glutamate ligase domain 323 406 6.9E-18 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TSC_c18700 15077d77c41569ea902a50cda14d8527 486 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 18 473 9.5E-127 T 12-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 TSC_c18700 15077d77c41569ea902a50cda14d8527 486 Gene3D G3DSA:3.40.1390.10 6 98 1.4E-21 T 12-10-2018 TSC_c18700 15077d77c41569ea902a50cda14d8527 486 SUPERFAMILY SSF63418 1 97 1.7E-20 T 12-10-2018 IPR035911 MurE/MurF, N-terminal TSC_c00290 9a9d5b171e80b3b6fc6b96b1114c5977 285 Pfam PF00005 ABC transporter 17 158 2.1E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c00290 9a9d5b171e80b3b6fc6b96b1114c5977 285 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c00290 9a9d5b171e80b3b6fc6b96b1114c5977 285 SUPERFAMILY SSF52540 2 218 3.99E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c00290 9a9d5b171e80b3b6fc6b96b1114c5977 285 Gene3D G3DSA:3.40.50.300 1 226 9.9E-70 T 12-10-2018 TSC_c00290 9a9d5b171e80b3b6fc6b96b1114c5977 285 SMART SM00382 26 205 2.3E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c17780 513572c914997ceb59253866a1d235c7 353 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 196 283 3.7E-11 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal TSC_c17780 513572c914997ceb59253866a1d235c7 353 SUPERFAMILY SSF53639 193 343 9.61E-24 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TSC_c17780 513572c914997ceb59253866a1d235c7 353 SMART SM01007 185 350 4.9E-5 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal TSC_c17780 513572c914997ceb59253866a1d235c7 353 Gene3D G3DSA:3.40.225.10 188 346 3.2E-22 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TSC_c06230 9b56c16ffccb11105bfc72f59d04b8fb 170 SUPERFAMILY SSF52255 10 168 2.62E-67 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 TSC_c06230 9b56c16ffccb11105bfc72f59d04b8fb 170 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 11 164 1.1E-67 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TSC_c06230 9b56c16ffccb11105bfc72f59d04b8fb 170 SMART SM01001 9 160 3.8E-104 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TSC_c06230 9b56c16ffccb11105bfc72f59d04b8fb 170 Gene3D G3DSA:3.40.50.7700 1 170 1.8E-74 T 12-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 TSC_c06230 9b56c16ffccb11105bfc72f59d04b8fb 170 Pfam PF00731 AIR carboxylase 11 158 8.8E-66 T 12-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 TSC_c06230 9b56c16ffccb11105bfc72f59d04b8fb 170 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 11 164 33.201 T 12-10-2018 IPR033747 Class I PurE TSC_c06230 9b56c16ffccb11105bfc72f59d04b8fb 170 PIRSF PIRSF001338 6 169 7.6E-67 T 12-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 TSC_c11440 54459baed4a43a3532f4420ddd34fdfd 264 Pfam PF09130 Domain of unknown function (DUF1932) 185 253 6.5E-12 T 12-10-2018 IPR015814 Phosphogluconate dehydrogenase, NAD-binding, putative, C-terminal TSC_c11440 54459baed4a43a3532f4420ddd34fdfd 264 Gene3D G3DSA:3.40.50.720 6 164 8.9E-32 T 12-10-2018 TSC_c11440 54459baed4a43a3532f4420ddd34fdfd 264 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 114 5.0E-8 T 12-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 TSC_c11440 54459baed4a43a3532f4420ddd34fdfd 264 Gene3D G3DSA:1.10.1040.10 166 263 1.1E-20 T 12-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 TSC_c11440 54459baed4a43a3532f4420ddd34fdfd 264 SUPERFAMILY SSF48179 158 257 2.89E-21 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSC_c11440 54459baed4a43a3532f4420ddd34fdfd 264 SUPERFAMILY SSF51735 6 156 4.54E-25 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c22360 741eef61c7f5373887bf6466c94ebdeb 65 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 3.3E-22 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22360 741eef61c7f5373887bf6466c94ebdeb 65 SUPERFAMILY SSF46561 1 63 9.68E-20 T 12-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22360 741eef61c7f5373887bf6466c94ebdeb 65 Gene3D G3DSA:1.10.287.310 1 65 3.7E-27 T 12-10-2018 TSC_c22360 741eef61c7f5373887bf6466c94ebdeb 65 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 17.727 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22360 741eef61c7f5373887bf6466c94ebdeb 65 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 12-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22360 741eef61c7f5373887bf6466c94ebdeb 65 Pfam PF00831 Ribosomal L29 protein 4 60 1.2E-20 T 12-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c13650 1de5f44192bb848097c88d811bb45451 144 Gene3D G3DSA:2.40.280.10 1 125 2.4E-51 T 12-10-2018 IPR023620 Small protein B TSC_c13650 1de5f44192bb848097c88d811bb45451 144 ProSitePatterns PS01317 SsrA-binding protein. 22 34 - T 12-10-2018 IPR020081 SsrA-binding protein, conserved site TSC_c13650 1de5f44192bb848097c88d811bb45451 144 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 4 128 1.0E-50 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 TSC_c13650 1de5f44192bb848097c88d811bb45451 144 TIGRFAM TIGR00086 smpB: SsrA-binding protein 4 142 3.4E-54 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 TSC_c13650 1de5f44192bb848097c88d811bb45451 144 Pfam PF01668 SmpB protein 5 142 7.6E-57 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 TSC_c13650 1de5f44192bb848097c88d811bb45451 144 Hamap MF_00023 SsrA-binding protein [smpB]. 1 144 65.581 T 12-10-2018 IPR000037 SsrA-binding protein GO:0003723 TSC_c13650 1de5f44192bb848097c88d811bb45451 144 SUPERFAMILY SSF74982 3 127 5.75E-49 T 12-10-2018 IPR023620 Small protein B TSC_c08060 95493c8595b55e2799c14c92b53af1c7 378 Gene3D G3DSA:3.40.50.261 231 378 9.0E-51 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSC_c08060 95493c8595b55e2799c14c92b53af1c7 378 SUPERFAMILY SSF52210 231 374 9.16E-46 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSC_c08060 95493c8595b55e2799c14c92b53af1c7 378 Pfam PF00549 CoA-ligase 255 355 2.0E-14 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSC_c08060 95493c8595b55e2799c14c92b53af1c7 378 Gene3D G3DSA:3.30.1490.20 21 96 3.4E-97 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSC_c08060 95493c8595b55e2799c14c92b53af1c7 378 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 373 1.1E-141 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSC_c08060 95493c8595b55e2799c14c92b53af1c7 378 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 375 39.986 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSC_c08060 95493c8595b55e2799c14c92b53af1c7 378 PIRSF PIRSF001554 1 377 2.5E-141 T 12-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSC_c08060 95493c8595b55e2799c14c92b53af1c7 378 Gene3D G3DSA:3.30.470.20 3 220 3.4E-97 T 12-10-2018 TSC_c08060 95493c8595b55e2799c14c92b53af1c7 378 SUPERFAMILY SSF56059 1 227 2.83E-76 T 12-10-2018 TSC_c08060 95493c8595b55e2799c14c92b53af1c7 378 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 248 273 - T 12-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSC_c08060 95493c8595b55e2799c14c92b53af1c7 378 Pfam PF08442 ATP-grasp domain 2 194 1.1E-75 T 12-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSC_c16780 bd160d8f6e643a937ae341602333d99e 249 SUPERFAMILY SSF51658 33 226 1.96E-30 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily TSC_c16780 bd160d8f6e643a937ae341602333d99e 249 Pfam PF01261 Xylose isomerase-like TIM barrel 52 203 2.1E-15 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TSC_c16780 bd160d8f6e643a937ae341602333d99e 249 Gene3D G3DSA:3.20.20.150 15 244 7.5E-64 T 12-10-2018 TSC_c14500 329ff53d34c0406fe919011816c5d9ae 352 Pfam PF01098 Cell cycle protein 30 342 2.8E-58 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSC_c11090 a5a7cc8cfb973f28af4bd3c1272fdcfc 148 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 17 106 1.4E-13 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c11090 a5a7cc8cfb973f28af4bd3c1272fdcfc 148 Gene3D G3DSA:1.10.760.10 18 148 5.8E-47 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c11090 a5a7cc8cfb973f28af4bd3c1272fdcfc 148 PRINTS PR00605 Class IC cytochrome C signature 84 106 8.0E-7 T 12-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 TSC_c11090 a5a7cc8cfb973f28af4bd3c1272fdcfc 148 PRINTS PR00605 Class IC cytochrome C signature 27 38 8.0E-7 T 12-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 TSC_c11090 a5a7cc8cfb973f28af4bd3c1272fdcfc 148 SUPERFAMILY SSF46626 20 116 1.49E-23 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c20440 442218a914483dfb9b13607a6ea171ed 387 Pfam PF00999 Sodium/hydrogen exchanger family 11 377 2.4E-67 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TSC_c20440 442218a914483dfb9b13607a6ea171ed 387 Gene3D G3DSA:1.20.1530.20 3 386 1.0E-135 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily TSC_c23740 e0fb10d874accfdfa15bd90d4b9b701d 451 Pfam PF01235 Sodium:alanine symporter family 65 440 3.8E-96 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TSC_c23740 e0fb10d874accfdfa15bd90d4b9b701d 451 TIGRFAM TIGR00835 agcS: amino acid carrier protein 21 435 5.2E-99 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TSC_c23740 e0fb10d874accfdfa15bd90d4b9b701d 451 PRINTS PR00175 Sodium/alanine symporter signature 96 118 4.5E-34 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TSC_c23740 e0fb10d874accfdfa15bd90d4b9b701d 451 PRINTS PR00175 Sodium/alanine symporter signature 410 430 4.5E-34 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TSC_c23740 e0fb10d874accfdfa15bd90d4b9b701d 451 PRINTS PR00175 Sodium/alanine symporter signature 187 205 4.5E-34 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TSC_c23740 e0fb10d874accfdfa15bd90d4b9b701d 451 PRINTS PR00175 Sodium/alanine symporter signature 215 234 4.5E-34 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TSC_c23740 e0fb10d874accfdfa15bd90d4b9b701d 451 PRINTS PR00175 Sodium/alanine symporter signature 309 327 4.5E-34 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TSC_c23740 e0fb10d874accfdfa15bd90d4b9b701d 451 PRINTS PR00175 Sodium/alanine symporter signature 351 373 4.5E-34 T 12-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 TSC_c15630 3c138cd5ab06109c15a3b848925a40fd 271 SUPERFAMILY SSF51658 4 268 8.9E-67 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily TSC_c15630 3c138cd5ab06109c15a3b848925a40fd 271 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 165 172 - T 12-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 TSC_c15630 3c138cd5ab06109c15a3b848925a40fd 271 Gene3D G3DSA:3.20.20.150 1 269 1.6E-89 T 12-10-2018 TSC_c15630 3c138cd5ab06109c15a3b848925a40fd 271 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 4 267 8.7E-59 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 TSC_c15630 3c138cd5ab06109c15a3b848925a40fd 271 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 203 219 - T 12-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 TSC_c15630 3c138cd5ab06109c15a3b848925a40fd 271 SMART SM00518 3 267 1.9E-57 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 TSC_c15630 3c138cd5ab06109c15a3b848925a40fd 271 Pfam PF01261 Xylose isomerase-like TIM barrel 21 227 2.1E-25 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TSC_c15630 3c138cd5ab06109c15a3b848925a40fd 271 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 267 32.283 T 12-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 TSC_c02810 6ffc13d6906cad173bb20c8208047691 400 Pfam PF13173 AAA domain 18 136 1.2E-20 T 12-10-2018 TSC_c02810 6ffc13d6906cad173bb20c8208047691 400 Pfam PF13635 Domain of unknown function (DUF4143) 179 334 7.0E-23 T 12-10-2018 IPR025420 Domain of unknown function DUF4143 TSC_c02810 6ffc13d6906cad173bb20c8208047691 400 SUPERFAMILY SSF52540 11 180 4.58E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c02810 6ffc13d6906cad173bb20c8208047691 400 SUPERFAMILY SSF46785 192 246 4.01E-5 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c22230 ba18c751fbec9cfe9cd0433901e4d4d3 184 Gene3D G3DSA:3.40.50.300 2 184 1.2E-66 T 12-10-2018 TSC_c22230 ba18c751fbec9cfe9cd0433901e4d4d3 184 ProSitePatterns PS00113 Adenylate kinase signature. 78 89 - T 12-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSC_c22230 ba18c751fbec9cfe9cd0433901e4d4d3 184 Pfam PF00406 Adenylate kinase 8 160 1.6E-50 T 12-10-2018 TSC_c22230 ba18c751fbec9cfe9cd0433901e4d4d3 184 PRINTS PR00094 Adenylate kinase signature 78 94 2.4E-35 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSC_c22230 ba18c751fbec9cfe9cd0433901e4d4d3 184 PRINTS PR00094 Adenylate kinase signature 6 19 2.4E-35 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSC_c22230 ba18c751fbec9cfe9cd0433901e4d4d3 184 PRINTS PR00094 Adenylate kinase signature 147 161 2.4E-35 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSC_c22230 ba18c751fbec9cfe9cd0433901e4d4d3 184 PRINTS PR00094 Adenylate kinase signature 34 48 2.4E-35 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSC_c22230 ba18c751fbec9cfe9cd0433901e4d4d3 184 PRINTS PR00094 Adenylate kinase signature 130 145 2.4E-35 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSC_c22230 ba18c751fbec9cfe9cd0433901e4d4d3 184 SUPERFAMILY SSF52540 4 182 3.93E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c22230 ba18c751fbec9cfe9cd0433901e4d4d3 184 Hamap MF_00235 Adenylate kinase [adk]. 3 183 44.545 T 12-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 TSC_c04550 630b71e5e5009466ad41ec573997ea8e 439 Hamap MF_00484 Glycogen synthase [glgA]. 1 437 40.887 T 12-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 TSC_c04550 630b71e5e5009466ad41ec573997ea8e 439 Pfam PF00534 Glycosyl transferases group 1 266 406 6.0E-18 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TSC_c04550 630b71e5e5009466ad41ec573997ea8e 439 SUPERFAMILY SSF53756 1 438 5.23E-108 T 12-10-2018 TSC_c04550 630b71e5e5009466ad41ec573997ea8e 439 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 436 8.6E-143 T 12-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 TSC_c04550 630b71e5e5009466ad41ec573997ea8e 439 Gene3D G3DSA:3.40.50.2000 228 421 4.8E-139 T 12-10-2018 TSC_c04550 630b71e5e5009466ad41ec573997ea8e 439 Gene3D G3DSA:3.40.50.2000 3 435 4.8E-139 T 12-10-2018 TSC_c04550 630b71e5e5009466ad41ec573997ea8e 439 Pfam PF08323 Starch synthase catalytic domain 2 215 9.9E-61 T 12-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 TSC_c01040 8af733fb7819dc74cc311c5705f8fc5e 253 Pfam PF05258 Protein of unknown function (DUF721) 5 90 2.7E-18 T 12-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 TSC_c18300 86deb7a2de4072bb042fe1ef915e2708 181 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 4 177 38.788 T 12-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 TSC_c18300 86deb7a2de4072bb042fe1ef915e2708 181 Pfam PF00156 Phosphoribosyl transferase domain 6 163 8.0E-23 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSC_c18300 86deb7a2de4072bb042fe1ef915e2708 181 SUPERFAMILY SSF53271 6 172 1.57E-45 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TSC_c18300 86deb7a2de4072bb042fe1ef915e2708 181 Gene3D G3DSA:3.40.50.2020 1 181 4.5E-65 T 12-10-2018 TSC_c01560 ab249921ae2d23f6731e715c73feee4c 160 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 2 152 4.7E-34 T 12-10-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like TSC_c01560 ab249921ae2d23f6731e715c73feee4c 160 SUPERFAMILY SSF56784 4 132 4.69E-21 T 12-10-2018 IPR036412 HAD-like superfamily TSC_c01560 ab249921ae2d23f6731e715c73feee4c 160 Pfam PF13242 HAD-hyrolase-like 93 131 1.7E-7 T 12-10-2018 TSC_c01560 ab249921ae2d23f6731e715c73feee4c 160 Gene3D G3DSA:3.40.50.1000 20 141 6.3E-17 T 12-10-2018 IPR023214 HAD superfamily TSC_c03410 550d7ac030a85e62b74d1d8be6ba01bd 155 Pfam PF00578 AhpC/TSA family 16 131 1.5E-15 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSC_c03410 550d7ac030a85e62b74d1d8be6ba01bd 155 SUPERFAMILY SSF52833 12 147 2.43E-30 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TSC_c03410 550d7ac030a85e62b74d1d8be6ba01bd 155 Gene3D G3DSA:3.40.30.10 9 152 1.2E-38 T 12-10-2018 TSC_c22840 a0fcf64d7dc74384d3fa9fb34e14a9c2 133 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 2 129 7.0E-36 T 12-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 TSC_c22840 a0fcf64d7dc74384d3fa9fb34e14a9c2 133 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 114 1.4E-22 T 12-10-2018 TSC_c22840 a0fcf64d7dc74384d3fa9fb34e14a9c2 133 Gene3D G3DSA:3.10.180.10 1 130 7.2E-35 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c22840 a0fcf64d7dc74384d3fa9fb34e14a9c2 133 SUPERFAMILY SSF54593 1 131 8.94E-30 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c20570 62f2708a96b50e3353cb0f6191fa1fe5 368 Gene3D G3DSA:3.40.630.40 133 367 1.2E-57 T 12-10-2018 TSC_c20570 62f2708a96b50e3353cb0f6191fa1fe5 368 Gene3D G3DSA:2.60.40.3500 63 132 1.7E-5 T 12-10-2018 TSC_c20570 62f2708a96b50e3353cb0f6191fa1fe5 368 SUPERFAMILY SSF53187 140 361 2.7E-47 T 12-10-2018 TSC_c20570 62f2708a96b50e3353cb0f6191fa1fe5 368 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 142 358 5.9E-45 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 TSC_c20570 62f2708a96b50e3353cb0f6191fa1fe5 368 SMART SM00646 205 358 5.4E-35 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 TSC_c20570 62f2708a96b50e3353cb0f6191fa1fe5 368 Pfam PF11741 AMIN domain 28 110 8.3E-6 T 12-10-2018 IPR021731 AMIN domain TSC_c08840 5926239535b6d6dc9787a302a61ec2c6 396 Gene3D G3DSA:2.40.50.100 217 255 4.0E-25 T 12-10-2018 TSC_c08840 5926239535b6d6dc9787a302a61ec2c6 396 Pfam PF13437 HlyD family secretion protein 220 311 2.9E-9 T 12-10-2018 TSC_c08840 5926239535b6d6dc9787a302a61ec2c6 396 SUPERFAMILY SSF111369 145 313 1.96E-11 T 12-10-2018 TSC_c08840 5926239535b6d6dc9787a302a61ec2c6 396 Gene3D G3DSA:2.40.50.100 62 161 7.2E-11 T 12-10-2018 TSC_c08840 5926239535b6d6dc9787a302a61ec2c6 396 SUPERFAMILY SSF56954 4 216 7.72E-10 T 12-10-2018 TSC_c08840 5926239535b6d6dc9787a302a61ec2c6 396 Gene3D G3DSA:2.40.420.20 324 391 4.0E-25 T 12-10-2018 TSC_c08840 5926239535b6d6dc9787a302a61ec2c6 396 Gene3D G3DSA:2.40.30.170 256 323 4.0E-25 T 12-10-2018 TSC_c08840 5926239535b6d6dc9787a302a61ec2c6 396 Gene3D G3DSA:2.40.30.170 45 61 7.2E-11 T 12-10-2018 TSC_c08840 5926239535b6d6dc9787a302a61ec2c6 396 Gene3D G3DSA:1.10.287.470 163 216 4.0E-25 T 12-10-2018 TSC_c08840 5926239535b6d6dc9787a302a61ec2c6 396 Gene3D G3DSA:1.10.287.470 95 154 7.2E-11 T 12-10-2018 TSC_c11550 7802f9c4348ce230a720f9898719a1a6 260 Gene3D G3DSA:3.30.450.40 73 253 1.4E-61 T 12-10-2018 IPR029016 GAF-like domain superfamily TSC_c11550 7802f9c4348ce230a720f9898719a1a6 260 SUPERFAMILY SSF55781 59 248 4.25E-53 T 12-10-2018 TSC_c11550 7802f9c4348ce230a720f9898719a1a6 260 SMART SM00346 2 91 2.4E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSC_c11550 7802f9c4348ce230a720f9898719a1a6 260 Pfam PF09339 IclR helix-turn-helix domain 5 53 3.3E-14 T 12-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 TSC_c11550 7802f9c4348ce230a720f9898719a1a6 260 SUPERFAMILY SSF46785 3 73 4.79E-17 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c11550 7802f9c4348ce230a720f9898719a1a6 260 Gene3D G3DSA:1.10.10.10 2 72 4.2E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c11550 7802f9c4348ce230a720f9898719a1a6 260 Pfam PF01614 Bacterial transcriptional regulator 123 242 1.6E-34 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal TSC_c00420 0adedacda5a6aa88676dcaa0b24ac609 183 Pfam PF01966 HD domain 22 88 6.4E-8 T 12-10-2018 IPR006674 HD domain TSC_c00420 0adedacda5a6aa88676dcaa0b24ac609 183 TIGRFAM TIGR00277 HDIG: HDIG domain 18 88 3.5E-9 T 12-10-2018 IPR006675 HDIG domain TSC_c00420 0adedacda5a6aa88676dcaa0b24ac609 183 SMART SM00471 16 121 3.9E-4 T 12-10-2018 IPR003607 HD/PDEase domain TSC_c00420 0adedacda5a6aa88676dcaa0b24ac609 183 SUPERFAMILY SSF109604 17 154 2.29E-18 T 12-10-2018 TSC_c00420 0adedacda5a6aa88676dcaa0b24ac609 183 Gene3D G3DSA:1.10.3210.10 11 177 1.0E-9 T 12-10-2018 TSC_c08220 76c4457706afbcf6a04a332edef9ac29 522 Pfam PF02384 N-6 DNA Methylase 157 481 2.2E-94 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TSC_c08220 76c4457706afbcf6a04a332edef9ac29 522 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 292 304 4.2E-18 T 12-10-2018 TSC_c08220 76c4457706afbcf6a04a332edef9ac29 522 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 180 196 4.2E-18 T 12-10-2018 TSC_c08220 76c4457706afbcf6a04a332edef9ac29 522 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 204 218 4.2E-18 T 12-10-2018 TSC_c08220 76c4457706afbcf6a04a332edef9ac29 522 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 327 351 4.2E-18 T 12-10-2018 TSC_c08220 76c4457706afbcf6a04a332edef9ac29 522 Gene3D G3DSA:3.40.50.150 157 465 3.2E-91 T 12-10-2018 TSC_c08220 76c4457706afbcf6a04a332edef9ac29 522 Pfam PF12161 HsdM N-terminal domain 6 144 2.2E-30 T 12-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain TSC_c08220 76c4457706afbcf6a04a332edef9ac29 522 SUPERFAMILY SSF53335 5 517 8.3E-126 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c08220 76c4457706afbcf6a04a332edef9ac29 522 Gene3D G3DSA:1.20.1260.30 1 148 4.8E-22 T 12-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily TSC_c21430 77d4ece225ee776b322ccefd795385fa 311 Gene3D G3DSA:3.30.479.30 104 218 1.4E-7 T 12-10-2018 TSC_c21430 77d4ece225ee776b322ccefd795385fa 311 Pfam PF01145 SPFH domain / Band 7 family 44 230 2.5E-36 T 12-10-2018 IPR001107 Band 7 domain TSC_c21430 77d4ece225ee776b322ccefd795385fa 311 SUPERFAMILY SSF117892 73 220 3.27E-18 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily TSC_c21430 77d4ece225ee776b322ccefd795385fa 311 SMART SM00244 40 215 6.2E-16 T 12-10-2018 IPR001107 Band 7 domain TSC_c17360 8a1203cf3a39917b1141725febe819f1 212 Gene3D G3DSA:1.20.144.10 118 211 2.4E-26 T 12-10-2018 TSC_c17360 8a1203cf3a39917b1141725febe819f1 212 Gene3D G3DSA:1.20.144.10 16 117 8.4E-6 T 12-10-2018 TSC_c17360 8a1203cf3a39917b1141725febe819f1 212 Pfam PF01569 PAP2 superfamily 90 197 1.8E-24 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TSC_c17360 8a1203cf3a39917b1141725febe819f1 212 SUPERFAMILY SSF48317 13 200 8.5E-37 T 12-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily TSC_c17360 8a1203cf3a39917b1141725febe819f1 212 SMART SM00014 91 198 1.1E-22 T 12-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase TSC_c21860 56f448fb28dabb4cd6b47cb68da60ba0 407 SUPERFAMILY SSF53383 7 407 1.5E-178 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c21860 56f448fb28dabb4cd6b47cb68da60ba0 407 PIRSF PIRSF000412 2 404 1.7E-172 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TSC_c21860 56f448fb28dabb4cd6b47cb68da60ba0 407 Gene3D G3DSA:3.40.640.10 33 284 1.1E-185 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c21860 56f448fb28dabb4cd6b47cb68da60ba0 407 Pfam PF00464 Serine hydroxymethyltransferase 7 381 2.0E-172 T 12-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TSC_c21860 56f448fb28dabb4cd6b47cb68da60ba0 407 Gene3D G3DSA:3.90.1150.10 8 387 1.1E-185 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c21860 56f448fb28dabb4cd6b47cb68da60ba0 407 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 406 52.614 T 12-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TSC_c21860 56f448fb28dabb4cd6b47cb68da60ba0 407 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 12-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 TSC_c06350 d9002484bdbd3e68f63c34e29a93e7f2 269 SUPERFAMILY SSF69572 2 260 1.57E-99 T 12-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 TSC_c06350 d9002484bdbd3e68f63c34e29a93e7f2 269 Gene3D G3DSA:3.40.50.720 3 258 8.0E-96 T 12-10-2018 TSC_c06350 d9002484bdbd3e68f63c34e29a93e7f2 269 Pfam PF00899 ThiF family 10 247 2.2E-68 T 12-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 TSC_c22930 67b736e87bed4a119cb89e35ab6acc59 595 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 9 426 5.0E-150 T 12-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 TSC_c22930 67b736e87bed4a119cb89e35ab6acc59 595 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 485 550 3.6E-6 T 12-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 TSC_c22930 67b736e87bed4a119cb89e35ab6acc59 595 SUPERFAMILY SSF50475 2 320 1.33E-108 T 12-10-2018 TSC_c22930 67b736e87bed4a119cb89e35ab6acc59 595 Gene3D G3DSA:3.40.1670.10 335 450 2.0E-23 T 12-10-2018 TSC_c22930 67b736e87bed4a119cb89e35ab6acc59 595 Gene3D G3DSA:3.40.1670.10 479 570 1.6E-5 T 12-10-2018 TSC_c22930 67b736e87bed4a119cb89e35ab6acc59 595 SUPERFAMILY SSF143968 486 595 2.22E-19 T 12-10-2018 TSC_c22930 67b736e87bed4a119cb89e35ab6acc59 595 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 8 451 6.2E-120 T 12-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 TSC_c22930 67b736e87bed4a119cb89e35ab6acc59 595 SUPERFAMILY SSF143968 321 459 3.14E-35 T 12-10-2018 TSC_c22930 67b736e87bed4a119cb89e35ab6acc59 595 TIGRFAM TIGR03701 mena_SCO4490: menaquinone biosynthesis decarboxylase, SCO4490 family 8 443 1.1E-187 T 12-10-2018 IPR022390 4-hydroxybenzoate decarboxylase subunit C GO:0016831 TSC_c13860 6c93794f4605b6c6f20b12056e3664d5 239 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 221 1.4E-82 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TSC_c13860 6c93794f4605b6c6f20b12056e3664d5 239 Gene3D G3DSA:3.40.1280.10 1 160 3.5E-60 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSC_c13860 6c93794f4605b6c6f20b12056e3664d5 239 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 216 6.3E-63 T 12-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TSC_c13860 6c93794f4605b6c6f20b12056e3664d5 239 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 239 96.485 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TSC_c13860 6c93794f4605b6c6f20b12056e3664d5 239 Gene3D G3DSA:1.10.1270.20 161 239 1.0E-28 T 12-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TSC_c13860 6c93794f4605b6c6f20b12056e3664d5 239 PIRSF PIRSF000386 1 238 6.9E-97 T 12-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 TSC_c13860 6c93794f4605b6c6f20b12056e3664d5 239 SUPERFAMILY SSF75217 1 236 2.35E-87 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases TSC_c10520 36be96b409d558b045b80dbeba94fb8a 151 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 17 127 6.6E-45 T 12-10-2018 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 TSC_c10520 36be96b409d558b045b80dbeba94fb8a 151 Gene3D G3DSA:3.10.129.10 11 127 1.9E-46 T 12-10-2018 TSC_c10520 36be96b409d558b045b80dbeba94fb8a 151 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 15 125 7.0E-24 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 TSC_c10520 36be96b409d558b045b80dbeba94fb8a 151 Pfam PF03061 Thioesterase superfamily 45 116 7.6E-16 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TSC_c10520 36be96b409d558b045b80dbeba94fb8a 151 SUPERFAMILY SSF54637 10 126 2.68E-31 T 12-10-2018 IPR029069 HotDog domain superfamily TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 SUPERFAMILY SSF52374 8 691 1.48E-154 T 12-10-2018 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 SUPERFAMILY SSF47323 686 881 6.35E-36 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 PRINTS PR00985 Leucyl-tRNA synthetase signature 158 174 1.7E-51 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 PRINTS PR00985 Leucyl-tRNA synthetase signature 498 516 1.7E-51 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 PRINTS PR00985 Leucyl-tRNA synthetase signature 537 559 1.7E-51 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 PRINTS PR00985 Leucyl-tRNA synthetase signature 570 580 1.7E-51 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 PRINTS PR00985 Leucyl-tRNA synthetase signature 132 149 1.7E-51 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 PRINTS PR00985 Leucyl-tRNA synthetase signature 220 239 1.7E-51 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 PRINTS PR00985 Leucyl-tRNA synthetase signature 191 204 1.7E-51 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 Gene3D G3DSA:3.40.50.620 39 651 0.0 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 9 881 0.0 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 Gene3D G3DSA:2.30.210.10 585 641 0.0 T 12-10-2018 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 8 881 22.911 T 12-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 Gene3D G3DSA:3.90.740.10 233 422 0.0 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 Pfam PF08264 Anticodon-binding domain of tRNA 723 847 3.6E-23 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 47 58 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 Gene3D G3DSA:1.10.730.10 660 818 7.6E-60 T 12-10-2018 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 226 411 2.3E-70 T 12-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 SUPERFAMILY SSF50677 231 422 3.56E-58 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 Pfam PF09334 tRNA synthetases class I (M) 41 181 8.1E-20 T 12-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 Gene3D G3DSA:3.10.20.590 820 883 2.6E-24 T 12-10-2018 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 424 583 1.1E-5 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c24690 5f43fcaf352dafda85a3b83fb5be2914 883 Pfam PF14795 Leucine-tRNA synthetase-specific domain 585 640 1.5E-29 T 12-10-2018 IPR023356 Leucyl-tRNA synthetase, domain 3 TSC_c15760 55ceee9e9e56e9a47d688d6726da1a40 148 Pfam PF13643 Domain of unknown function (DUF4145) 25 100 8.0E-13 T 12-10-2018 IPR025285 Domain of unknown function DUF4145 TSC_c21510 c66197d254ec638ce78bed65c78d8e93 107 Gene3D G3DSA:3.30.428.10 1 106 1.6E-38 T 12-10-2018 IPR036265 HIT-like superfamily TSC_c21510 c66197d254ec638ce78bed65c78d8e93 107 SUPERFAMILY SSF54197 1 104 1.19E-33 T 12-10-2018 IPR036265 HIT-like superfamily TSC_c21510 c66197d254ec638ce78bed65c78d8e93 107 PRINTS PR00332 Histidine triad family signature 25 43 8.4E-20 T 12-10-2018 IPR001310 Histidine triad (HIT) protein TSC_c21510 c66197d254ec638ce78bed65c78d8e93 107 PRINTS PR00332 Histidine triad family signature 4 20 8.4E-20 T 12-10-2018 IPR001310 Histidine triad (HIT) protein TSC_c21510 c66197d254ec638ce78bed65c78d8e93 107 PRINTS PR00332 Histidine triad family signature 93 103 8.4E-20 T 12-10-2018 IPR001310 Histidine triad (HIT) protein TSC_c21510 c66197d254ec638ce78bed65c78d8e93 107 Pfam PF01230 HIT domain 11 105 2.8E-26 T 12-10-2018 IPR001310 Histidine triad (HIT) protein TSC_c22010 41046b63e3c35309ab29a154304639b8 340 Gene3D G3DSA:3.40.910.10 3 326 1.4E-92 T 12-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 TSC_c22010 41046b63e3c35309ab29a154304639b8 340 SUPERFAMILY SSF52467 2 328 1.54E-100 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSC_c22010 41046b63e3c35309ab29a154304639b8 340 Pfam PF01916 Deoxyhypusine synthase 24 317 1.0E-93 T 12-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 TSC_c22010 41046b63e3c35309ab29a154304639b8 340 Hamap MF_00640 Deoxyhypusine synthase-like protein. 3 340 46.127 T 12-10-2018 IPR023496 Deoxyhypusine synthase-like GO:0016765 TSC_c11760 5d02f73b13dead0ca80f8ce8a6551c9c 222 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 21 192 9.6E-46 T 12-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 TSC_c11760 5d02f73b13dead0ca80f8ce8a6551c9c 222 SUPERFAMILY SSF52402 3 181 7.61E-50 T 12-10-2018 TSC_c11760 5d02f73b13dead0ca80f8ce8a6551c9c 222 Gene3D G3DSA:3.40.50.620 1 222 3.8E-66 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c11760 5d02f73b13dead0ca80f8ce8a6551c9c 222 PIRSF PIRSF000857 1 222 1.2E-72 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 TSC_c11760 5d02f73b13dead0ca80f8ce8a6551c9c 222 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 22 216 3.4E-60 T 12-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 TSC_c20850 714ea1586420e10d3cd7e26e815d1c21 292 Pfam PF08544 GHMP kinases C terminal 200 269 2.1E-10 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain TSC_c20850 714ea1586420e10d3cd7e26e815d1c21 292 SUPERFAMILY SSF55060 158 274 1.03E-31 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TSC_c20850 714ea1586420e10d3cd7e26e815d1c21 292 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 84 95 - T 12-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 TSC_c20850 714ea1586420e10d3cd7e26e815d1c21 292 Gene3D G3DSA:3.30.230.10 6 148 1.5E-38 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSC_c20850 714ea1586420e10d3cd7e26e815d1c21 292 SUPERFAMILY SSF54211 7 152 6.45E-27 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c20850 714ea1586420e10d3cd7e26e815d1c21 292 PRINTS PR00958 Homoserine kinase signature 125 138 1.2E-33 T 12-10-2018 TSC_c20850 714ea1586420e10d3cd7e26e815d1c21 292 PRINTS PR00958 Homoserine kinase signature 91 106 1.2E-33 T 12-10-2018 TSC_c20850 714ea1586420e10d3cd7e26e815d1c21 292 PRINTS PR00958 Homoserine kinase signature 12 27 1.2E-33 T 12-10-2018 TSC_c20850 714ea1586420e10d3cd7e26e815d1c21 292 PRINTS PR00958 Homoserine kinase signature 241 256 1.2E-33 T 12-10-2018 TSC_c20850 714ea1586420e10d3cd7e26e815d1c21 292 PRINTS PR00958 Homoserine kinase signature 162 179 1.2E-33 T 12-10-2018 TSC_c20850 714ea1586420e10d3cd7e26e815d1c21 292 Hamap MF_00384 Homoserine kinase [thrB]. 7 291 27.694 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TSC_c20850 714ea1586420e10d3cd7e26e815d1c21 292 Gene3D G3DSA:3.30.70.890 156 276 7.8E-40 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TSC_c20850 714ea1586420e10d3cd7e26e815d1c21 292 TIGRFAM TIGR00191 thrB: homoserine kinase 7 270 3.8E-65 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TSC_c20850 714ea1586420e10d3cd7e26e815d1c21 292 PIRSF PIRSF000676 2 282 1.6E-75 T 12-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 TSC_c20850 714ea1586420e10d3cd7e26e815d1c21 292 Pfam PF00288 GHMP kinases N terminal domain 82 138 3.7E-10 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TSC_c05020 266cc58d1eb8d0e0af2b00fc74e8f4c2 282 Gene3D G3DSA:1.10.3720.10 70 278 7.0E-22 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c05020 266cc58d1eb8d0e0af2b00fc74e8f4c2 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 281 5.5E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c05020 266cc58d1eb8d0e0af2b00fc74e8f4c2 282 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 3 56 2.3E-9 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TSC_c05020 266cc58d1eb8d0e0af2b00fc74e8f4c2 282 SUPERFAMILY SSF161098 74 266 1.83E-26 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c02410 38919ec4e5db19ec6e3d54e984cf3541 137 SUPERFAMILY SSF75217 2 135 3.4E-33 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases TSC_c02410 38919ec4e5db19ec6e3d54e984cf3541 137 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 136 24.884 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 TSC_c02410 38919ec4e5db19ec6e3d54e984cf3541 137 Pfam PF02590 Predicted SPOUT methyltransferase 2 135 1.2E-32 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 TSC_c02410 38919ec4e5db19ec6e3d54e984cf3541 137 Gene3D G3DSA:3.40.1280.10 1 137 2.4E-37 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSC_c02410 38919ec4e5db19ec6e3d54e984cf3541 137 PIRSF PIRSF004505 38 136 6.4E-27 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 TSC_c02410 38919ec4e5db19ec6e3d54e984cf3541 137 PIRSF PIRSF004505 1 49 2.4E-4 T 12-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 TSC_c19250 45e771376a6506b14f49e9c8f7df45b0 574 SUPERFAMILY SSF51445 279 564 6.69E-52 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TSC_c19250 45e771376a6506b14f49e9c8f7df45b0 574 Gene3D G3DSA:3.20.20.80 279 565 8.3E-48 T 12-10-2018 TSC_c19250 45e771376a6506b14f49e9c8f7df45b0 574 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 315 428 1.9E-10 T 12-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 TSC_c19250 45e771376a6506b14f49e9c8f7df45b0 574 SUPERFAMILY SSF49785 5 168 8.22E-37 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TSC_c19250 45e771376a6506b14f49e9c8f7df45b0 574 Gene3D G3DSA:2.60.120.260 4 168 1.1E-30 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TSC_c10540 d15252ef720cb00f020250262bb1fdf1 140 PIRSF PIRSF014972 1 136 4.5E-39 T 12-10-2018 IPR025540 Fluoroacetyl-CoA thioesterase TSC_c10540 d15252ef720cb00f020250262bb1fdf1 140 Gene3D G3DSA:3.10.129.10 1 139 3.8E-38 T 12-10-2018 TSC_c10540 d15252ef720cb00f020250262bb1fdf1 140 SUPERFAMILY SSF54637 2 135 3.4E-39 T 12-10-2018 IPR029069 HotDog domain superfamily TSC_c04190 676b7e0c6167fbe76848d818711ffe00 343 SUPERFAMILY SSF53067 6 141 1.48E-33 T 12-10-2018 TSC_c04190 676b7e0c6167fbe76848d818711ffe00 343 Gene3D G3DSA:3.90.640.10 179 254 4.5E-125 T 12-10-2018 TSC_c04190 676b7e0c6167fbe76848d818711ffe00 343 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 5 330 5.8E-140 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TSC_c04190 676b7e0c6167fbe76848d818711ffe00 343 SUPERFAMILY SSF53067 143 328 1.94E-49 T 12-10-2018 TSC_c04190 676b7e0c6167fbe76848d818711ffe00 343 Gene3D G3DSA:3.30.420.40 7 322 4.5E-125 T 12-10-2018 TSC_c04190 676b7e0c6167fbe76848d818711ffe00 343 Gene3D G3DSA:3.30.420.40 147 312 4.5E-125 T 12-10-2018 TSC_c04190 676b7e0c6167fbe76848d818711ffe00 343 Pfam PF06723 MreB/Mbl protein 5 329 5.5E-137 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TSC_c04190 676b7e0c6167fbe76848d818711ffe00 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 180 200 3.1E-55 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TSC_c04190 676b7e0c6167fbe76848d818711ffe00 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 62 85 3.1E-55 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TSC_c04190 676b7e0c6167fbe76848d818711ffe00 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 125 144 3.1E-55 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TSC_c04190 676b7e0c6167fbe76848d818711ffe00 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 295 321 3.1E-55 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TSC_c04190 676b7e0c6167fbe76848d818711ffe00 343 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 42 60 3.1E-55 T 12-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 TSC_c09380 99d3c80c579815e74419f89dbda9cb12 192 Pfam PF01205 Uncharacterized protein family UPF0029 16 116 4.5E-29 T 12-10-2018 IPR001498 Impact, N-terminal TSC_c09380 99d3c80c579815e74419f89dbda9cb12 192 Gene3D G3DSA:3.30.230.30 1 125 4.8E-50 T 12-10-2018 IPR036956 Impact, N-terminal domain superfamily TSC_c09380 99d3c80c579815e74419f89dbda9cb12 192 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 71 100 - T 12-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site TSC_c09380 99d3c80c579815e74419f89dbda9cb12 192 Gene3D G3DSA:3.30.70.240 126 191 5.1E-21 T 12-10-2018 TSC_c09380 99d3c80c579815e74419f89dbda9cb12 192 Pfam PF09186 Domain of unknown function (DUF1949) 134 187 3.5E-10 T 12-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal TSC_c09380 99d3c80c579815e74419f89dbda9cb12 192 SUPERFAMILY SSF54211 4 121 1.37E-39 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c09380 99d3c80c579815e74419f89dbda9cb12 192 SUPERFAMILY SSF54980 126 190 5.52E-17 T 12-10-2018 IPR035647 EF-G domain III/V-like TSC_c11980 bdd8bfa032b054a8559a0ecf8f283fca 235 Pfam PF07729 FCD domain 91 212 8.4E-30 T 12-10-2018 IPR011711 GntR, C-terminal TSC_c11980 bdd8bfa032b054a8559a0ecf8f283fca 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 8 69 2.2E-18 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSC_c11980 bdd8bfa032b054a8559a0ecf8f283fca 235 SMART SM00895 91 213 7.9E-27 T 12-10-2018 IPR011711 GntR, C-terminal TSC_c11980 bdd8bfa032b054a8559a0ecf8f283fca 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 1.7E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSC_c11980 bdd8bfa032b054a8559a0ecf8f283fca 235 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 1.7E-9 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSC_c11980 bdd8bfa032b054a8559a0ecf8f283fca 235 Gene3D G3DSA:1.10.10.10 1 75 9.1E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c11980 bdd8bfa032b054a8559a0ecf8f283fca 235 Gene3D G3DSA:1.20.120.530 76 218 2.3E-33 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSC_c11980 bdd8bfa032b054a8559a0ecf8f283fca 235 SUPERFAMILY SSF48008 89 217 9.42E-31 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSC_c11980 bdd8bfa032b054a8559a0ecf8f283fca 235 SMART SM00345 10 69 8.3E-19 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSC_c11980 bdd8bfa032b054a8559a0ecf8f283fca 235 SUPERFAMILY SSF46785 3 73 2.73E-20 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c14680 3a98c9022577176a18f21e5badfdcc0c 861 Gene3D G3DSA:3.40.50.740 124 650 2.7E-299 T 12-10-2018 TSC_c14680 3a98c9022577176a18f21e5badfdcc0c 861 Gene3D G3DSA:2.40.40.20 717 852 2.0E-49 T 12-10-2018 TSC_c14680 3a98c9022577176a18f21e5badfdcc0c 861 SUPERFAMILY SSF53706 10 704 2.2E-141 T 12-10-2018 TSC_c14680 3a98c9022577176a18f21e5badfdcc0c 861 SUPERFAMILY SSF50692 691 841 3.62E-36 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSC_c14680 3a98c9022577176a18f21e5badfdcc0c 861 Gene3D G3DSA:3.40.228.10 207 710 2.7E-299 T 12-10-2018 TSC_c14680 3a98c9022577176a18f21e5badfdcc0c 861 Gene3D G3DSA:3.30.200.200 13 687 2.7E-299 T 12-10-2018 TSC_c14680 3a98c9022577176a18f21e5badfdcc0c 861 Pfam PF01568 Molydopterin dinucleotide binding domain 729 834 5.4E-24 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSC_c14680 3a98c9022577176a18f21e5badfdcc0c 861 Pfam PF00384 Molybdopterin oxidoreductase 123 593 1.3E-38 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c14680 3a98c9022577176a18f21e5badfdcc0c 861 TIGRFAM TIGR02693 arsenite_ox_L: arsenite oxidase, large subunit 10 841 0.0 T 12-10-2018 IPR014066 Arsenite oxidase, large subunit MetaCyc: PWY-7429 TSC_c13600 e2250482afd8dd26bacc7ead58401b8a 250 Gene3D G3DSA:3.20.20.70 1 250 5.0E-103 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c13600 e2250482afd8dd26bacc7ead58401b8a 250 ProSitePatterns PS00171 Triosephosphate isomerase active site. 164 174 - T 12-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13600 e2250482afd8dd26bacc7ead58401b8a 250 Pfam PF00121 Triosephosphate isomerase 5 245 2.5E-87 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13600 e2250482afd8dd26bacc7ead58401b8a 250 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 248 55.752 T 12-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13600 e2250482afd8dd26bacc7ead58401b8a 250 SUPERFAMILY SSF51351 1 247 1.1E-85 T 12-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13600 e2250482afd8dd26bacc7ead58401b8a 250 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 238 5.2E-52 T 12-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c07860 00f7bf50f8fc158b55a1cb29927b9a2f 353 Pfam PF07995 Glucose / Sorbosone dehydrogenase 31 339 3.9E-91 T 12-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase TSC_c07860 00f7bf50f8fc158b55a1cb29927b9a2f 353 Gene3D G3DSA:2.120.10.30 21 353 7.9E-145 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TSC_c07860 00f7bf50f8fc158b55a1cb29927b9a2f 353 SUPERFAMILY SSF50952 21 338 3.14E-45 T 12-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 TSC_c10870 6bf0a56d789d6e609ad9ecd3507d65d3 387 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 244 263 5.4E-13 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSC_c10870 6bf0a56d789d6e609ad9ecd3507d65d3 387 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 47 65 5.4E-13 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSC_c10870 6bf0a56d789d6e609ad9ecd3507d65d3 387 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 67 79 5.4E-13 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSC_c10870 6bf0a56d789d6e609ad9ecd3507d65d3 387 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 343 356 5.4E-13 T 12-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 TSC_c10870 6bf0a56d789d6e609ad9ecd3507d65d3 387 PRINTS PR01181 Diaminopimelate decarboxylase signature 271 289 5.2E-16 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSC_c10870 6bf0a56d789d6e609ad9ecd3507d65d3 387 PRINTS PR01181 Diaminopimelate decarboxylase signature 149 158 5.2E-16 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSC_c10870 6bf0a56d789d6e609ad9ecd3507d65d3 387 PRINTS PR01181 Diaminopimelate decarboxylase signature 65 82 5.2E-16 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSC_c10870 6bf0a56d789d6e609ad9ecd3507d65d3 387 PRINTS PR01181 Diaminopimelate decarboxylase signature 353 375 5.2E-16 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSC_c10870 6bf0a56d789d6e609ad9ecd3507d65d3 387 Gene3D G3DSA:2.40.37.10 12 376 7.3E-93 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TSC_c10870 6bf0a56d789d6e609ad9ecd3507d65d3 387 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 47 65 - T 12-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site TSC_c10870 6bf0a56d789d6e609ad9ecd3507d65d3 387 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 23 343 4.3E-21 T 12-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 TSC_c10870 6bf0a56d789d6e609ad9ecd3507d65d3 387 SUPERFAMILY SSF50621 235 385 2.51E-44 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TSC_c10870 6bf0a56d789d6e609ad9ecd3507d65d3 387 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 7 386 33.91 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSC_c10870 6bf0a56d789d6e609ad9ecd3507d65d3 387 SUPERFAMILY SSF51419 18 256 5.23E-52 T 12-10-2018 IPR029066 PLP-binding barrel TSC_c10870 6bf0a56d789d6e609ad9ecd3507d65d3 387 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 28 254 3.3E-37 T 12-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 TSC_c10870 6bf0a56d789d6e609ad9ecd3507d65d3 387 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 9 385 1.9E-93 T 12-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSC_c10870 6bf0a56d789d6e609ad9ecd3507d65d3 387 Gene3D G3DSA:3.20.20.10 26 249 7.3E-93 T 12-10-2018 IPR029066 PLP-binding barrel TSC_c06620 925d815eba0e6a0a9c25d3fa520e1b88 297 SUPERFAMILY SSF55785 17 74 1.88E-5 T 12-10-2018 IPR035965 PAS domain superfamily TSC_c06620 925d815eba0e6a0a9c25d3fa520e1b88 297 SUPERFAMILY SSF47384 89 153 1.18E-9 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSC_c06620 925d815eba0e6a0a9c25d3fa520e1b88 297 PRINTS PR00344 Bacterial sensor protein C-terminal signature 259 277 7.6E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c06620 925d815eba0e6a0a9c25d3fa520e1b88 297 PRINTS PR00344 Bacterial sensor protein C-terminal signature 230 244 7.6E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c06620 925d815eba0e6a0a9c25d3fa520e1b88 297 PRINTS PR00344 Bacterial sensor protein C-terminal signature 282 295 7.6E-7 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c06620 925d815eba0e6a0a9c25d3fa520e1b88 297 SMART SM00387 195 297 6.8E-15 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c06620 925d815eba0e6a0a9c25d3fa520e1b88 297 Gene3D G3DSA:3.30.450.20 2 104 7.6E-6 T 12-10-2018 TSC_c06620 925d815eba0e6a0a9c25d3fa520e1b88 297 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 195 284 6.5E-11 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c06620 925d815eba0e6a0a9c25d3fa520e1b88 297 SUPERFAMILY SSF55874 163 292 1.96E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c06620 925d815eba0e6a0a9c25d3fa520e1b88 297 Gene3D G3DSA:1.10.287.130 105 157 4.2E-6 T 12-10-2018 TSC_c06620 925d815eba0e6a0a9c25d3fa520e1b88 297 Gene3D G3DSA:3.30.565.10 159 297 1.3E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c06620 925d815eba0e6a0a9c25d3fa520e1b88 297 SMART SM00388 98 160 6.6E-6 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c06620 925d815eba0e6a0a9c25d3fa520e1b88 297 Pfam PF00512 His Kinase A (phospho-acceptor) domain 99 152 1.3E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c17790 93988563a9f402dd3d64a07437159969 370 Pfam PF00107 Zinc-binding dehydrogenase 196 327 2.1E-18 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSC_c17790 93988563a9f402dd3d64a07437159969 370 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 43 155 8.1E-14 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSC_c17790 93988563a9f402dd3d64a07437159969 370 Gene3D G3DSA:3.90.180.10 40 350 6.6E-62 T 12-10-2018 TSC_c17790 93988563a9f402dd3d64a07437159969 370 Gene3D G3DSA:3.40.50.720 174 313 6.6E-62 T 12-10-2018 TSC_c17790 93988563a9f402dd3d64a07437159969 370 SUPERFAMILY SSF51735 162 328 2.44E-21 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c17790 93988563a9f402dd3d64a07437159969 370 SUPERFAMILY SSF50129 29 194 4.87E-24 T 12-10-2018 IPR011032 GroES-like superfamily TSC_c08390 15f22594bc505bbdcfd5511d4adeae4e 562 Gene3D G3DSA:3.40.50.970 1 172 5.3E-70 T 12-10-2018 TSC_c08390 15f22594bc505bbdcfd5511d4adeae4e 562 Gene3D G3DSA:3.40.50.1220 184 347 4.1E-65 T 12-10-2018 TSC_c08390 15f22594bc505bbdcfd5511d4adeae4e 562 Gene3D G3DSA:3.40.50.970 351 561 1.4E-68 T 12-10-2018 TSC_c08390 15f22594bc505bbdcfd5511d4adeae4e 562 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 1 551 1.7E-243 T 12-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 TSC_c08390 15f22594bc505bbdcfd5511d4adeae4e 562 SUPERFAMILY SSF52467 182 349 2.36E-63 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSC_c08390 15f22594bc505bbdcfd5511d4adeae4e 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 190 323 2.7E-48 T 12-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 TSC_c08390 15f22594bc505bbdcfd5511d4adeae4e 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 167 1.6E-57 T 12-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 TSC_c08390 15f22594bc505bbdcfd5511d4adeae4e 562 SUPERFAMILY SSF52518 1 169 1.22E-62 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c08390 15f22594bc505bbdcfd5511d4adeae4e 562 SUPERFAMILY SSF52518 358 557 6.27E-68 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c08390 15f22594bc505bbdcfd5511d4adeae4e 562 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 416 435 - T 12-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 TSC_c08390 15f22594bc505bbdcfd5511d4adeae4e 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 379 527 2.3E-51 T 12-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 TSC_c19420 a4a11f842ec56860a22fecb1dcebe7a9 131 Pfam PF11432 Protein of unknown function (DUF3197) 15 126 1.3E-42 T 12-10-2018 IPR024443 Domain of unknown function DUF3197 TSC_c19420 a4a11f842ec56860a22fecb1dcebe7a9 131 SUPERFAMILY SSF143592 1 127 2.09E-49 T 12-10-2018 IPR036828 TTHA1528-like superfamily TSC_c19420 a4a11f842ec56860a22fecb1dcebe7a9 131 Gene3D G3DSA:3.40.1530.10 1 131 3.9E-59 T 12-10-2018 IPR036828 TTHA1528-like superfamily TSC_c24710 0ce8cc9462310eadf9fde9c15b4f371f 423 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 12 422 39.05 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TSC_c24710 0ce8cc9462310eadf9fde9c15b4f371f 423 PIRSF PIRSF000151 5 423 1.1E-157 T 12-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 TSC_c24710 0ce8cc9462310eadf9fde9c15b4f371f 423 Pfam PF00171 Aldehyde dehydrogenase family 52 289 2.0E-15 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSC_c24710 0ce8cc9462310eadf9fde9c15b4f371f 423 Gene3D G3DSA:3.40.309.10 232 380 1.4E-152 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSC_c24710 0ce8cc9462310eadf9fde9c15b4f371f 423 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 329 350 - T 12-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TSC_c24710 0ce8cc9462310eadf9fde9c15b4f371f 423 SUPERFAMILY SSF53720 20 421 1.27E-106 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSC_c24710 0ce8cc9462310eadf9fde9c15b4f371f 423 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 22 412 9.2E-133 T 12-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 TSC_c24710 0ce8cc9462310eadf9fde9c15b4f371f 423 Gene3D G3DSA:3.40.605.10 25 417 1.4E-152 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 Gene3D G3DSA:3.30.565.10 10 217 3.2E-82 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 Gene3D G3DSA:3.40.50.670 396 635 2.8E-107 T 12-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 Pfam PF00204 DNA gyrase B 219 388 1.7E-53 T 12-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 Pfam PF01751 Toprim domain 417 533 7.7E-19 T 12-10-2018 IPR006171 TOPRIM domain TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 SUPERFAMILY SSF54211 219 389 1.9E-50 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 SMART SM00433 32 629 0.0 T 12-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 SUPERFAMILY SSF55874 3 211 1.96E-65 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR01159 DNA gyrase subunit B signature 194 207 6.7E-52 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR01159 DNA gyrase subunit B signature 218 240 6.7E-52 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR01159 DNA gyrase subunit B signature 372 392 6.7E-52 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR01159 DNA gyrase subunit B signature 358 372 6.7E-52 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR01159 DNA gyrase subunit B signature 468 477 6.7E-52 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR01159 DNA gyrase subunit B signature 310 326 6.7E-52 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR01159 DNA gyrase subunit B signature 605 621 6.7E-52 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR01159 DNA gyrase subunit B signature 589 601 6.7E-52 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR01159 DNA gyrase subunit B signature 179 194 6.7E-52 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR01159 DNA gyrase subunit B signature 3 13 6.7E-52 T 12-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 ProSitePatterns PS00177 DNA topoisomerase II signature. 420 428 - T 12-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 Gene3D G3DSA:3.30.230.10 218 390 2.8E-65 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 SUPERFAMILY SSF56719 392 629 2.54E-88 T 12-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 SMART SM00387 28 174 2.5E-20 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR00418 DNA topoisomerase II family signature 489 505 1.6E-69 T 12-10-2018 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR00418 DNA topoisomerase II family signature 32 47 1.6E-69 T 12-10-2018 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR00418 DNA topoisomerase II family signature 418 432 1.6E-69 T 12-10-2018 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR00418 DNA topoisomerase II family signature 110 124 1.6E-69 T 12-10-2018 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR00418 DNA topoisomerase II family signature 266 279 1.6E-69 T 12-10-2018 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR00418 DNA topoisomerase II family signature 527 539 1.6E-69 T 12-10-2018 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR00418 DNA topoisomerase II family signature 568 584 1.6E-69 T 12-10-2018 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR00418 DNA topoisomerase II family signature 67 80 1.6E-69 T 12-10-2018 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 PRINTS PR00418 DNA topoisomerase II family signature 507 524 1.6E-69 T 12-10-2018 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 564 625 1.5E-29 T 12-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 TSC_c22740 3553e15181083d6d27a4ab09d202f2fd 635 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 172 1.5E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c10910 c6e977ec013f14bdf45eed7a42b36cec 263 SUPERFAMILY SSF48695 92 252 1.26E-14 T 12-10-2018 IPR036280 Multiheme cytochrome superfamily TSC_c10910 c6e977ec013f14bdf45eed7a42b36cec 263 Pfam PF14522 Cytochrome c7 and related cytochrome c 84 176 3.4E-9 T 12-10-2018 IPR029467 C-type polyheme cytochrome OmcB TSC_c10910 c6e977ec013f14bdf45eed7a42b36cec 263 Gene3D G3DSA:3.90.10.10 73 179 8.2E-12 T 12-10-2018 TSC_c13060 b216c41518ecbd0c1a88580a595b03de 521 SUPERFAMILY SSF52096 12 261 2.8E-78 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSC_c13060 b216c41518ecbd0c1a88580a595b03de 521 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 100 114 3.4E-6 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c13060 b216c41518ecbd0c1a88580a595b03de 521 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 170 187 3.4E-6 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c13060 b216c41518ecbd0c1a88580a595b03de 521 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 199 210 3.4E-6 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c13060 b216c41518ecbd0c1a88580a595b03de 521 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 134 152 3.4E-6 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c13060 b216c41518ecbd0c1a88580a595b03de 521 Gene3D G3DSA:3.90.226.10 265 521 1.0E-92 T 12-10-2018 TSC_c13060 b216c41518ecbd0c1a88580a595b03de 521 Pfam PF01039 Carboxyl transferase domain 34 519 7.4E-187 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TSC_c13060 b216c41518ecbd0c1a88580a595b03de 521 Gene3D G3DSA:3.90.226.10 8 263 1.3E-93 T 12-10-2018 TSC_c13060 b216c41518ecbd0c1a88580a595b03de 521 SUPERFAMILY SSF52096 269 521 3.22E-90 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSC_c14890 cd344eb55c61d6de819a60729fe9cc5f 198 SMART SM00418 3 85 0.0072 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c14890 cd344eb55c61d6de819a60729fe9cc5f 198 SUPERFAMILY SSF46785 7 180 4.56E-24 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c14890 cd344eb55c61d6de819a60729fe9cc5f 198 Gene3D G3DSA:1.10.10.10 2 78 5.9E-13 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c14890 cd344eb55c61d6de819a60729fe9cc5f 198 Pfam PF01022 Bacterial regulatory protein, arsR family 11 52 1.1E-7 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c15160 1a0486c52f2b16166ace17ca37f7509e 252 Pfam PF00588 SpoU rRNA Methylase family 5 157 1.9E-37 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TSC_c15160 1a0486c52f2b16166ace17ca37f7509e 252 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 233 4.2E-68 T 12-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 TSC_c15160 1a0486c52f2b16166ace17ca37f7509e 252 Gene3D G3DSA:3.40.1280.10 1 167 3.9E-57 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSC_c15160 1a0486c52f2b16166ace17ca37f7509e 252 SUPERFAMILY SSF75217 4 168 3.73E-33 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases TSC_c15160 1a0486c52f2b16166ace17ca37f7509e 252 PIRSF PIRSF004808 1 243 7.5E-74 T 12-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 TSC_c15160 1a0486c52f2b16166ace17ca37f7509e 252 Gene3D G3DSA:1.10.8.590 168 245 3.5E-15 T 12-10-2018 TSC_c08770 e065a84479f3058ab7be148c04acaf85 106 Pfam PF01990 ATP synthase (F/14-kDa) subunit 3 83 5.8E-14 T 12-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c08770 e065a84479f3058ab7be148c04acaf85 106 SUPERFAMILY SSF159468 3 105 6.28E-22 T 12-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c08770 e065a84479f3058ab7be148c04acaf85 106 Gene3D G3DSA:3.40.50.10580 3 102 1.7E-20 T 12-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c08770 e065a84479f3058ab7be148c04acaf85 106 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 1 105 18.651 T 12-10-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal TSC_c07010 fc04ca32d8eba075210a35bcdf362cd7 371 Gene3D G3DSA:1.10.1130.10 32 175 7.7E-6 T 12-10-2018 TSC_c07010 fc04ca32d8eba075210a35bcdf362cd7 371 SUPERFAMILY SSF48695 47 366 1.4E-22 T 12-10-2018 IPR036280 Multiheme cytochrome superfamily TSC_c12010 f9ac2e3e9e4f271dd0661cf3db34c358 281 SUPERFAMILY SSF161098 72 258 2.75E-29 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c12010 f9ac2e3e9e4f271dd0661cf3db34c358 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 277 6.4E-33 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c12010 f9ac2e3e9e4f271dd0661cf3db34c358 281 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 4 53 4.6E-5 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TSC_c12010 f9ac2e3e9e4f271dd0661cf3db34c358 281 Gene3D G3DSA:1.10.3720.10 67 273 1.7E-24 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c22280 b1872264071ccf4f566bb4ff5908549e 112 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 6 112 1.3E-38 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22280 b1872264071ccf4f566bb4ff5908549e 112 Gene3D G3DSA:3.30.420.100 1 112 1.7E-41 T 12-10-2018 TSC_c22280 b1872264071ccf4f566bb4ff5908549e 112 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 3 112 6.8E-40 T 12-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22280 b1872264071ccf4f566bb4ff5908549e 112 SUPERFAMILY SSF53137 6 110 1.22E-47 T 12-10-2018 TSC_c22280 b1872264071ccf4f566bb4ff5908549e 112 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 112 26.894 T 12-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c16790 904ff503bb995fbbc1f3ef58ed3f598e 302 Gene3D G3DSA:1.10.3720.10 59 299 1.2E-67 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c16790 904ff503bb995fbbc1f3ef58ed3f598e 302 SUPERFAMILY SSF161098 63 288 6.41E-61 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c16790 904ff503bb995fbbc1f3ef58ed3f598e 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 294 1.8E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c09520 8c638ad03e710790e28878b004b5a532 617 SUPERFAMILY SSF56801 4 589 4.06E-106 T 12-10-2018 TSC_c09520 8c638ad03e710790e28878b004b5a532 617 Gene3D G3DSA:3.40.50.12780 308 455 3.7E-38 T 12-10-2018 TSC_c09520 8c638ad03e710790e28878b004b5a532 617 Pfam PF00501 AMP-binding enzyme 11 455 2.2E-80 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSC_c09520 8c638ad03e710790e28878b004b5a532 617 Gene3D G3DSA:3.40.50.12780 1 307 1.9E-43 T 12-10-2018 TSC_c09520 8c638ad03e710790e28878b004b5a532 617 ProSitePatterns PS00455 Putative AMP-binding domain signature. 173 184 - T 12-10-2018 IPR020845 AMP-binding, conserved site TSC_c19350 ea7c3a656e37abd2d74d2be5c98368cf 190 Gene3D G3DSA:3.90.1570.10 5 182 3.0E-22 T 12-10-2018 TSC_c19350 ea7c3a656e37abd2d74d2be5c98368cf 190 SUPERFAMILY SSF52980 7 178 1.18E-27 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSC_c19350 ea7c3a656e37abd2d74d2be5c98368cf 190 Pfam PF05685 Putative restriction endonuclease 13 166 2.2E-32 T 12-10-2018 IPR008538 Domain of unknown function DUF820 TSC_c14700 4dbd272a39e89cb3daab5b5719f52238 160 Pfam PF00355 Rieske [2Fe-2S] domain 40 132 1.8E-10 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TSC_c14700 4dbd272a39e89cb3daab5b5719f52238 160 SUPERFAMILY SSF50022 2 146 5.76E-27 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSC_c14700 4dbd272a39e89cb3daab5b5719f52238 160 Gene3D G3DSA:2.102.10.10 33 160 3.3E-38 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSC_c14700 4dbd272a39e89cb3daab5b5719f52238 160 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 5 25 1.7E-4 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TSC_c14700 4dbd272a39e89cb3daab5b5719f52238 160 TIGRFAM TIGR02694 arsenite_ox_S: arsenite oxidase, small subunit 34 160 4.3E-66 T 12-10-2018 IPR014067 Arsenite oxidase, small subunit MetaCyc: PWY-7429 TSC_c08800 084d875ea4863d71d972b7a5f49842b6 223 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 1 203 3.4E-46 T 12-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c08800 084d875ea4863d71d972b7a5f49842b6 223 Pfam PF01813 ATP synthase subunit D 10 198 1.0E-51 T 12-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c08800 084d875ea4863d71d972b7a5f49842b6 223 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 1 204 24.334 T 12-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c05440 c9589d4644e1f24d7f052792fb55f040 520 Gene3D G3DSA:3.20.20.360 5 402 3.1E-190 T 12-10-2018 TSC_c05440 c9589d4644e1f24d7f052792fb55f040 520 Pfam PF01274 Malate synthase 15 519 4.1E-202 T 12-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TSC_c05440 c9589d4644e1f24d7f052792fb55f040 520 SUPERFAMILY SSF51645 15 519 2.09E-189 T 12-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TSC_c05440 c9589d4644e1f24d7f052792fb55f040 520 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 16 519 4.2E-237 T 12-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TSC_c05440 c9589d4644e1f24d7f052792fb55f040 520 PIRSF PIRSF001363 1 520 7.2E-248 T 12-10-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TSC_c05440 c9589d4644e1f24d7f052792fb55f040 520 Gene3D G3DSA:1.20.1220.12 405 519 9.0E-44 T 12-10-2018 TSC_c05440 c9589d4644e1f24d7f052792fb55f040 520 ProSitePatterns PS00510 Malate synthase signature. 258 273 - T 12-10-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 TSC_c24350 dd193e5f260683ae84417a5d06b924b2 237 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 6 232 1.0E-64 T 12-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 TSC_c24350 dd193e5f260683ae84417a5d06b924b2 237 SUPERFAMILY SSF143597 33 219 1.16E-53 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily TSC_c24350 dd193e5f260683ae84417a5d06b924b2 237 Gene3D G3DSA:3.40.1700.10 92 236 1.1E-46 T 12-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily TSC_c24350 dd193e5f260683ae84417a5d06b924b2 237 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 104 217 9.0E-35 T 12-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal TSC_c24350 dd193e5f260683ae84417a5d06b924b2 237 Hamap MF_01499 Diadenylate cyclase [dacA]. 1 236 31.187 T 12-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 TSC_c24350 dd193e5f260683ae84417a5d06b924b2 237 PIRSF PIRSF004793 2 237 1.6E-77 T 12-10-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 TSC_c08140 e2a9a5bcd73e8245b92177dc07fad1da 331 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 115 8.7E-30 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSC_c08140 e2a9a5bcd73e8245b92177dc07fad1da 331 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 1 328 35.383 T 12-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSC_c08140 e2a9a5bcd73e8245b92177dc07fad1da 331 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 134 314 1.3E-54 T 12-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSC_c08140 e2a9a5bcd73e8245b92177dc07fad1da 331 Gene3D G3DSA:3.30.360.10 123 311 1.6E-146 T 12-10-2018 TSC_c08140 e2a9a5bcd73e8245b92177dc07fad1da 331 PIRSF PIRSF000148 1 330 1.8E-124 T 12-10-2018 TSC_c08140 e2a9a5bcd73e8245b92177dc07fad1da 331 Gene3D G3DSA:3.40.50.720 3 325 1.6E-146 T 12-10-2018 TSC_c08140 e2a9a5bcd73e8245b92177dc07fad1da 331 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 2 328 1.8E-123 T 12-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 TSC_c08140 e2a9a5bcd73e8245b92177dc07fad1da 331 SUPERFAMILY SSF51735 2 151 1.01E-44 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c08140 e2a9a5bcd73e8245b92177dc07fad1da 331 SUPERFAMILY SSF55347 124 315 3.42E-74 T 12-10-2018 TSC_c08140 e2a9a5bcd73e8245b92177dc07fad1da 331 SMART SM00859 2 116 1.6E-41 T 12-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 TSC_c10840 c192ea3f22bef92f9ab28f6b810c6199 424 Pfam PF01547 Bacterial extracellular solute-binding protein 30 319 8.3E-53 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSC_c10840 c192ea3f22bef92f9ab28f6b810c6199 424 SUPERFAMILY SSF53850 20 409 3.61E-80 T 12-10-2018 TSC_c10840 c192ea3f22bef92f9ab28f6b810c6199 424 Gene3D G3DSA:3.40.190.10 18 423 3.8E-103 T 12-10-2018 TSC_c06420 baad6593df9bfdc9ccd5e3e993bcd888 191 Gene3D G3DSA:3.40.1280.10 1 191 2.9E-76 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSC_c06420 baad6593df9bfdc9ccd5e3e993bcd888 191 SUPERFAMILY SSF75217 3 186 1.18E-51 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases TSC_c06420 baad6593df9bfdc9ccd5e3e993bcd888 191 Hamap MF_02060 tRNA (guanosine(18)-2'-O)-methyltransferase [trmH]. 2 191 35.214 T 12-10-2018 IPR033671 tRNA (guanosine(18)-2'-O)-methyltransferase GO:0008168|GO:0030488 TSC_c06420 baad6593df9bfdc9ccd5e3e993bcd888 191 Pfam PF00588 SpoU rRNA Methylase family 20 159 6.5E-36 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TSC_c06420 baad6593df9bfdc9ccd5e3e993bcd888 191 Pfam PF12105 SpoU, rRNA methylase, C-terminal 163 185 8.1E-6 T 12-10-2018 IPR022724 RNA methyltransferase, SpoU/TrmH type, C-terminal GO:0009020 TSC_c19610 34958a632ece1e4ce5af8b75b2674aba 477 Pfam PF03477 ATP cone domain 182 256 2.0E-6 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TSC_c19610 34958a632ece1e4ce5af8b75b2674aba 477 SUPERFAMILY SSF52540 259 461 1.29E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c19610 34958a632ece1e4ce5af8b75b2674aba 477 Gene3D G3DSA:3.40.50.300 256 461 3.3E-9 T 12-10-2018 TSC_c13140 dca67de9bb6c86aa0fc10ad666713a38 412 SUPERFAMILY SSF53383 5 410 2.61E-92 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c13140 dca67de9bb6c86aa0fc10ad666713a38 412 Gene3D G3DSA:3.40.640.10 1 277 7.0E-88 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c13140 dca67de9bb6c86aa0fc10ad666713a38 412 PIRSF PIRSF001434 1 412 8.0E-117 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSC_c13140 dca67de9bb6c86aa0fc10ad666713a38 412 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 410 3.5E-105 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSC_c13140 dca67de9bb6c86aa0fc10ad666713a38 412 Gene3D G3DSA:3.90.1150.10 278 411 5.0E-44 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c01570 2aa87450a5674970dfb4f3014e11109f 161 PIRSF PIRSF030042 28 161 2.5E-44 T 12-10-2018 IPR016942 Uncharacterised conserved protein UCP030042 TSC_c01570 2aa87450a5674970dfb4f3014e11109f 161 Pfam PF14340 Domain of unknown function (DUF4395) 31 152 6.2E-28 T 12-10-2018 IPR025508 Domain of unknown function DUF4395 TSC_c07740 84e5ed84e94ff2079e144f47cd964c08 396 SUPERFAMILY SSF53901 274 395 1.53E-34 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c07740 84e5ed84e94ff2079e144f47cd964c08 396 PIRSF PIRSF000429 1 396 1.0E-125 T 12-10-2018 IPR002155 Thiolase GO:0016747 TSC_c07740 84e5ed84e94ff2079e144f47cd964c08 396 ProSitePatterns PS00737 Thiolases signature 2. 342 358 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 TSC_c07740 84e5ed84e94ff2079e144f47cd964c08 396 Gene3D G3DSA:3.40.47.10 5 279 1.4E-142 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c07740 84e5ed84e94ff2079e144f47cd964c08 396 SUPERFAMILY SSF53901 3 273 5.76E-86 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c07740 84e5ed84e94ff2079e144f47cd964c08 396 Pfam PF02803 Thiolase, C-terminal domain 273 394 9.8E-35 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TSC_c07740 84e5ed84e94ff2079e144f47cd964c08 396 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 394 3.6E-133 T 12-10-2018 IPR002155 Thiolase GO:0016747 TSC_c07740 84e5ed84e94ff2079e144f47cd964c08 396 Pfam PF00108 Thiolase, N-terminal domain 4 266 7.7E-89 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TSC_c07740 84e5ed84e94ff2079e144f47cd964c08 396 Gene3D G3DSA:3.40.47.10 126 392 1.4E-142 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c23700 1805e1f3409266c6ea3cbc2a0b23afcb 158 Pfam PF04073 Aminoacyl-tRNA editing domain 30 145 3.3E-28 T 12-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 TSC_c23700 1805e1f3409266c6ea3cbc2a0b23afcb 158 Gene3D G3DSA:3.90.960.10 2 157 3.3E-52 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TSC_c23700 1805e1f3409266c6ea3cbc2a0b23afcb 158 SUPERFAMILY SSF55826 9 155 5.36E-37 T 12-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 TSC_c02930 43adf0a5a8a4c6a2e16b3773aba4bf9b 302 SUPERFAMILY SSF53448 4 246 4.88E-45 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c02930 43adf0a5a8a4c6a2e16b3773aba4bf9b 302 Pfam PF00535 Glycosyl transferase family 2 5 114 1.8E-27 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSC_c02930 43adf0a5a8a4c6a2e16b3773aba4bf9b 302 Gene3D G3DSA:3.90.550.10 1 212 3.5E-39 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c01940 1860f64174a8128468aff0bea9261412 269 SUPERFAMILY SSF53633 2 268 7.07E-53 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSC_c01940 1860f64174a8128468aff0bea9261412 269 PRINTS PR00474 Glutamate 5-kinase family signature 28 42 3.2E-11 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TSC_c01940 1860f64174a8128468aff0bea9261412 269 PRINTS PR00474 Glutamate 5-kinase family signature 223 243 3.2E-11 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TSC_c01940 1860f64174a8128468aff0bea9261412 269 PRINTS PR00474 Glutamate 5-kinase family signature 170 197 3.2E-11 T 12-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 TSC_c01940 1860f64174a8128468aff0bea9261412 269 Hamap MF_02082 [LysW]-aminoadipate/[LysW]-glutamate kinase [lysZ]. 1 269 49.08 T 12-10-2018 IPR037529 [LysW]-aminoadipate/[LysW]-glutamate kinase GO:0016301 TSC_c01940 1860f64174a8128468aff0bea9261412 269 TIGRFAM TIGR00761 argB: acetylglutamate kinase 1 247 2.4E-75 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSC_c01940 1860f64174a8128468aff0bea9261412 269 Pfam PF00696 Amino acid kinase family 2 248 4.2E-38 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSC_c01940 1860f64174a8128468aff0bea9261412 269 Gene3D G3DSA:3.40.1160.10 1 269 1.9E-74 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSC_c01940 1860f64174a8128468aff0bea9261412 269 PIRSF PIRSF000728 1 269 3.2E-70 T 12-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 TSC_c07450 df792ec9fc02d9a0cf00fac54b041b13 648 SUPERFAMILY SSF56801 18 645 4.58E-190 T 12-10-2018 TSC_c07450 df792ec9fc02d9a0cf00fac54b041b13 648 Gene3D G3DSA:3.40.50.12780 61 518 6.7E-109 T 12-10-2018 TSC_c07450 df792ec9fc02d9a0cf00fac54b041b13 648 Gene3D G3DSA:3.30.300.30 521 647 1.2E-33 T 12-10-2018 TSC_c07450 df792ec9fc02d9a0cf00fac54b041b13 648 Pfam PF13193 AMP-binding enzyme C-terminal domain 534 612 1.9E-32 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSC_c07450 df792ec9fc02d9a0cf00fac54b041b13 648 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 27 646 0.0 T 12-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 TSC_c07450 df792ec9fc02d9a0cf00fac54b041b13 648 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 9 648 54.41 T 12-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 TSC_c07450 df792ec9fc02d9a0cf00fac54b041b13 648 Pfam PF00501 AMP-binding enzyme 87 525 1.5E-95 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSC_c07450 df792ec9fc02d9a0cf00fac54b041b13 648 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 32 85 8.0E-23 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 TSC_c07450 df792ec9fc02d9a0cf00fac54b041b13 648 ProSitePatterns PS00455 Putative AMP-binding domain signature. 263 274 - T 12-10-2018 IPR020845 AMP-binding, conserved site TSC_c09990 b8ddc50a89f89acccfe875fc8e402b4a 125 SUPERFAMILY SSF81301 2 117 5.45E-18 T 12-10-2018 TSC_c09990 b8ddc50a89f89acccfe875fc8e402b4a 125 Pfam PF01909 Nucleotidyltransferase domain 21 58 1.3E-8 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSC_c09990 b8ddc50a89f89acccfe875fc8e402b4a 125 Gene3D G3DSA:3.30.460.10 5 122 6.3E-12 T 12-10-2018 TSC_c04370 36c2616036c40e779b17a5646d2997db 376 Gene3D G3DSA:1.20.1250.20 1 366 2.3E-25 T 12-10-2018 TSC_c04370 36c2616036c40e779b17a5646d2997db 376 SUPERFAMILY SSF103473 2 374 4.97E-28 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c04370 36c2616036c40e779b17a5646d2997db 376 Pfam PF07690 Major Facilitator Superfamily 7 294 5.9E-14 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c01240 381e82da1a268df15b2d229675b67ed4 413 SUPERFAMILY SSF53244 279 403 3.3E-19 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSC_c01240 381e82da1a268df15b2d229675b67ed4 413 SUPERFAMILY SSF53623 3 275 1.57E-83 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSC_c01240 381e82da1a268df15b2d229675b67ed4 413 Gene3D G3DSA:3.40.1190.10 1 278 4.3E-89 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSC_c01240 381e82da1a268df15b2d229675b67ed4 413 Gene3D G3DSA:3.90.190.20 280 404 1.1E-20 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSC_c01240 381e82da1a268df15b2d229675b67ed4 413 Pfam PF08245 Mur ligase middle domain 40 257 1.5E-18 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TSC_c01240 381e82da1a268df15b2d229675b67ed4 413 TIGRFAM TIGR01499 folC: bifunctional protein FolC 18 402 2.8E-99 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 TSC_c01240 381e82da1a268df15b2d229675b67ed4 413 PIRSF PIRSF001563 2 407 3.2E-107 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 TSC_c08540 82d0fc203d9c8aa3321a6436a2ae9755 205 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 13 168 1.3E-59 T 12-10-2018 IPR005273 Uracil-DNA glycosylase family 4 TSC_c08540 82d0fc203d9c8aa3321a6436a2ae9755 205 Pfam PF03167 Uracil DNA glycosylase superfamily 27 165 3.1E-48 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSC_c08540 82d0fc203d9c8aa3321a6436a2ae9755 205 SMART SM00987 27 179 5.5E-42 T 12-10-2018 TSC_c08540 82d0fc203d9c8aa3321a6436a2ae9755 205 SUPERFAMILY SSF52141 3 186 1.08E-68 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSC_c08540 82d0fc203d9c8aa3321a6436a2ae9755 205 SMART SM00986 27 179 5.5E-42 T 12-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSC_c08540 82d0fc203d9c8aa3321a6436a2ae9755 205 Gene3D G3DSA:3.40.470.10 1 205 4.7E-85 T 12-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 TSC_c14710 7999a596354f855d6ac8865f2c28a3eb 302 Gene3D G3DSA:3.20.20.410 1 299 3.7E-75 T 12-10-2018 IPR036520 UPF0759 superfamily TSC_c14710 7999a596354f855d6ac8865f2c28a3eb 302 SUPERFAMILY SSF117396 2 291 1.06E-69 T 12-10-2018 IPR036520 UPF0759 superfamily TSC_c14710 7999a596354f855d6ac8865f2c28a3eb 302 Pfam PF01904 Protein of unknown function DUF72 22 287 1.1E-57 T 12-10-2018 IPR002763 Protein of unknown function DUF72 TSC_c08780 8e843505f627f191bcd6ea59bc43eb60 578 Gene3D G3DSA:2.40.30.20 1 71 8.0E-31 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSC_c08780 8e843505f627f191bcd6ea59bc43eb60 578 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 84 199 5.9E-43 T 12-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c08780 8e843505f627f191bcd6ea59bc43eb60 578 SUPERFAMILY SSF52540 145 433 5.08E-81 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c08780 8e843505f627f191bcd6ea59bc43eb60 578 Gene3D G3DSA:2.40.50.100 115 181 1.9E-179 T 12-10-2018 TSC_c08780 8e843505f627f191bcd6ea59bc43eb60 578 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 1 577 51.024 T 12-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c08780 8e843505f627f191bcd6ea59bc43eb60 578 SUPERFAMILY SSF50615 3 70 6.28E-12 T 12-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSC_c08780 8e843505f627f191bcd6ea59bc43eb60 578 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 68 3.5E-14 T 12-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSC_c08780 8e843505f627f191bcd6ea59bc43eb60 578 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 420 429 - T 12-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSC_c08780 8e843505f627f191bcd6ea59bc43eb60 578 Gene3D G3DSA:3.40.50.300 73 429 1.9E-179 T 12-10-2018 TSC_c08780 8e843505f627f191bcd6ea59bc43eb60 578 Gene3D G3DSA:1.10.1140.10 430 578 3.7E-50 T 12-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSC_c08780 8e843505f627f191bcd6ea59bc43eb60 578 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 208 429 8.3E-90 T 12-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSC_c08780 8e843505f627f191bcd6ea59bc43eb60 578 SUPERFAMILY SSF47917 442 548 2.2E-25 T 12-10-2018 TSC_c18050 bc7d98fcc5f3e5287dfb365bfa42f70e 210 Pfam PF00571 CBS domain 77 130 5.4E-15 T 12-10-2018 IPR000644 CBS domain TSC_c18050 bc7d98fcc5f3e5287dfb365bfa42f70e 210 Pfam PF00571 CBS domain 3 56 4.3E-17 T 12-10-2018 IPR000644 CBS domain TSC_c18050 bc7d98fcc5f3e5287dfb365bfa42f70e 210 SUPERFAMILY SSF54631 1 132 3.54E-38 T 12-10-2018 TSC_c18050 bc7d98fcc5f3e5287dfb365bfa42f70e 210 SMART SM00116 10 57 1.0E-13 T 12-10-2018 IPR000644 CBS domain TSC_c18050 bc7d98fcc5f3e5287dfb365bfa42f70e 210 SMART SM00116 84 131 5.0E-14 T 12-10-2018 IPR000644 CBS domain TSC_c18050 bc7d98fcc5f3e5287dfb365bfa42f70e 210 Gene3D G3DSA:3.10.580.10 1 142 1.7E-43 T 12-10-2018 TSC_c17000 13d798c8c5d86cb58377e3586414c414 367 Pfam PF13288 DXP reductoisomerase C-terminal domain 248 361 2.3E-35 T 12-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TSC_c17000 13d798c8c5d86cb58377e3586414c414 367 Gene3D G3DSA:3.40.50.720 1 138 7.0E-38 T 12-10-2018 TSC_c17000 13d798c8c5d86cb58377e3586414c414 367 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 366 41.189 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TSC_c17000 13d798c8c5d86cb58377e3586414c414 367 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 134 216 4.2E-34 T 12-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TSC_c17000 13d798c8c5d86cb58377e3586414c414 367 SUPERFAMILY SSF55347 114 250 1.6E-50 T 12-10-2018 TSC_c17000 13d798c8c5d86cb58377e3586414c414 367 SUPERFAMILY SSF69055 280 366 9.81E-25 T 12-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TSC_c17000 13d798c8c5d86cb58377e3586414c414 367 SUPERFAMILY SSF51735 2 138 7.75E-33 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c17000 13d798c8c5d86cb58377e3586414c414 367 Gene3D G3DSA:1.10.1740.10 288 367 9.3E-24 T 12-10-2018 TSC_c17000 13d798c8c5d86cb58377e3586414c414 367 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 364 1.7E-108 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TSC_c17000 13d798c8c5d86cb58377e3586414c414 367 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 120 4.8E-28 T 12-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TSC_c17000 13d798c8c5d86cb58377e3586414c414 367 PIRSF PIRSF006205 1 367 1.6E-127 T 12-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 TSC_c03140 20950ead2caba31451ad82f413b7f029 276 Gene3D G3DSA:3.30.1300.10 173 276 2.3E-29 T 12-10-2018 TSC_c03140 20950ead2caba31451ad82f413b7f029 276 Gene3D G3DSA:3.40.50.620 2 172 2.8E-77 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c03140 20950ead2caba31451ad82f413b7f029 276 Pfam PF02569 Pantoate-beta-alanine ligase 3 272 3.7E-98 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 TSC_c03140 20950ead2caba31451ad82f413b7f029 276 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 21 66 1.0E-8 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSC_c03140 20950ead2caba31451ad82f413b7f029 276 SUPERFAMILY SSF52374 3 274 1.79E-101 T 12-10-2018 TSC_c03140 20950ead2caba31451ad82f413b7f029 276 Hamap MF_00158 Pantothenate synthetase [panC]. 2 274 39.971 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 TSC_c03140 20950ead2caba31451ad82f413b7f029 276 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 1 274 7.9E-95 T 12-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 TSC_c01090 5375955c25ac8de0ba56b85745b99ea1 330 SUPERFAMILY SSF161098 42 314 8.63E-36 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c01090 5375955c25ac8de0ba56b85745b99ea1 330 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 25 322 1.4E-83 T 12-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 TSC_c01090 5375955c25ac8de0ba56b85745b99ea1 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 321 6.3E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c01090 5375955c25ac8de0ba56b85745b99ea1 330 Gene3D G3DSA:1.10.3720.10 71 324 6.8E-36 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c16980 ec5dc7d0afa0d53a209c0882bc376676 185 Gene3D G3DSA:3.30.1360.40 32 106 2.6E-71 T 12-10-2018 TSC_c16980 ec5dc7d0afa0d53a209c0882bc376676 185 SUPERFAMILY SSF55194 5 184 3.79E-68 T 12-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 TSC_c16980 ec5dc7d0afa0d53a209c0882bc376676 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 12 184 1.5E-67 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 TSC_c16980 ec5dc7d0afa0d53a209c0882bc376676 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 4 185 26.085 T 12-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 TSC_c16980 ec5dc7d0afa0d53a209c0882bc376676 185 Pfam PF01765 Ribosome recycling factor 21 184 1.4E-64 T 12-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 TSC_c16980 ec5dc7d0afa0d53a209c0882bc376676 185 Gene3D G3DSA:1.10.132.20 13 183 2.6E-71 T 12-10-2018 TSC_c24030 975ff1e9c45dfcee24d94bb6ffc12f66 126 ProSitePatterns PS00893 Nudix box signature. 31 52 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TSC_c24030 975ff1e9c45dfcee24d94bb6ffc12f66 126 SUPERFAMILY SSF55811 3 123 3.93E-29 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSC_c24030 975ff1e9c45dfcee24d94bb6ffc12f66 126 Pfam PF00293 NUDIX domain 4 107 2.6E-19 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSC_c24030 975ff1e9c45dfcee24d94bb6ffc12f66 126 PRINTS PR00502 NUDIX hydrolase family signature 40 55 5.0E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSC_c24030 975ff1e9c45dfcee24d94bb6ffc12f66 126 PRINTS PR00502 NUDIX hydrolase family signature 26 40 5.0E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSC_c24030 975ff1e9c45dfcee24d94bb6ffc12f66 126 Gene3D G3DSA:3.90.79.10 3 124 4.6E-40 T 12-10-2018 TSC_c14040 2098f08f3f28efff693b9a2628af01e4 400 Gene3D G3DSA:3.40.50.300 52 297 3.4E-101 T 12-10-2018 TSC_c14040 2098f08f3f28efff693b9a2628af01e4 400 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 1 396 48.694 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 TSC_c14040 2098f08f3f28efff693b9a2628af01e4 400 SMART SM00382 99 261 8.6E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c14040 2098f08f3f28efff693b9a2628af01e4 400 SUPERFAMILY SSF52540 56 388 7.16E-70 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c14040 2098f08f3f28efff693b9a2628af01e4 400 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 6 380 3.2E-169 T 12-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 TSC_c14040 2098f08f3f28efff693b9a2628af01e4 400 SMART SM00994 5 46 1.4E-13 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 TSC_c14040 2098f08f3f28efff693b9a2628af01e4 400 Gene3D G3DSA:1.10.8.60 298 399 6.1E-35 T 12-10-2018 TSC_c14040 2098f08f3f28efff693b9a2628af01e4 400 SUPERFAMILY SSF57716 6 43 1.05E-5 T 12-10-2018 TSC_c14040 2098f08f3f28efff693b9a2628af01e4 400 SMART SM01086 299 390 1.5E-28 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TSC_c14040 2098f08f3f28efff693b9a2628af01e4 400 Pfam PF07724 AAA domain (Cdc48 subfamily) 100 292 5.8E-48 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSC_c14040 2098f08f3f28efff693b9a2628af01e4 400 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 299 372 6.2E-16 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TSC_c14040 2098f08f3f28efff693b9a2628af01e4 400 Pfam PF06689 ClpX C4-type zinc finger 7 44 6.4E-11 T 12-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 TSC_c14040 2098f08f3f28efff693b9a2628af01e4 400 Gene3D G3DSA:3.30.50.30 2 46 2.4E-8 T 12-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily TSC_c19230 bf1a351a2c0dbf0b99d715d288a4fd73 690 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 274 416 1.5E-12 T 12-10-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 TSC_c19230 bf1a351a2c0dbf0b99d715d288a4fd73 690 Gene3D G3DSA:3.20.20.80 267 560 2.5E-63 T 12-10-2018 TSC_c19230 bf1a351a2c0dbf0b99d715d288a4fd73 690 SUPERFAMILY SSF49785 12 156 4.68E-10 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TSC_c19230 bf1a351a2c0dbf0b99d715d288a4fd73 690 Gene3D G3DSA:2.60.120.260 2 128 4.6E-7 T 12-10-2018 IPR008979 Galactose-binding-like domain superfamily TSC_c19230 bf1a351a2c0dbf0b99d715d288a4fd73 690 SUPERFAMILY SSF51445 264 562 2.51E-74 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TSC_c01760 2b8c66f164ba1fdc4d12868d59c54c22 60 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 5 59 2.4E-18 T 12-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 TSC_c01760 2b8c66f164ba1fdc4d12868d59c54c22 60 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 8 36 - T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSC_c01760 2b8c66f164ba1fdc4d12868d59c54c22 60 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 7 58 8.5E-16 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSC_c01760 2b8c66f164ba1fdc4d12868d59c54c22 60 Hamap MF_00422 Protein translocase subunit SecE [secE]. 3 58 12.222 T 12-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 TSC_c01760 2b8c66f164ba1fdc4d12868d59c54c22 60 Gene3D G3DSA:1.20.5.1030 1 60 2.9E-24 T 12-10-2018 IPR038379 SecE superfamily TSC_c11730 35059043c1925e99235726b930d92239 349 Pfam PF01747 ATP-sulfurylase 138 347 2.0E-82 T 12-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 TSC_c11730 35059043c1925e99235726b930d92239 349 Gene3D G3DSA:3.40.50.620 137 349 1.4E-94 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c11730 35059043c1925e99235726b930d92239 349 SUPERFAMILY SSF52374 139 347 8.44E-74 T 12-10-2018 TSC_c11730 35059043c1925e99235726b930d92239 349 SUPERFAMILY SSF88697 2 133 9.05E-37 T 12-10-2018 IPR015947 PUA-like superfamily TSC_c11730 35059043c1925e99235726b930d92239 349 Pfam PF14306 PUA-like domain 2 130 2.9E-37 T 12-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 TSC_c11730 35059043c1925e99235726b930d92239 349 Gene3D G3DSA:3.10.400.10 1 135 1.3E-45 T 12-10-2018 TSC_c11730 35059043c1925e99235726b930d92239 349 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 2 346 3.9E-103 T 12-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 TSC_c19980 1366cdc5ff7fd768b4a98c5a0bdb5c89 287 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 158 1.2E-30 T 12-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 TSC_c19980 1366cdc5ff7fd768b4a98c5a0bdb5c89 287 PRINTS PR00478 Phosphoribulokinase family signature 116 133 1.1E-9 T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 TSC_c19980 1366cdc5ff7fd768b4a98c5a0bdb5c89 287 PRINTS PR00478 Phosphoribulokinase family signature 134 157 1.1E-9 T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 TSC_c19980 1366cdc5ff7fd768b4a98c5a0bdb5c89 287 ProSitePatterns PS00567 Phosphoribulokinase signature. 116 129 - T 12-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 TSC_c19980 1366cdc5ff7fd768b4a98c5a0bdb5c89 287 Gene3D G3DSA:3.40.50.300 3 174 7.6E-37 T 12-10-2018 TSC_c19980 1366cdc5ff7fd768b4a98c5a0bdb5c89 287 SUPERFAMILY SSF52540 12 160 1.66E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c08430 c23b67bef698c002580535ac0d91d63e 550 Gene3D G3DSA:3.20.20.70 23 302 2.6E-78 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c08430 c23b67bef698c002580535ac0d91d63e 550 Pfam PF08502 LeuA allosteric (dimerisation) domain 415 536 1.3E-17 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSC_c08430 c23b67bef698c002580535ac0d91d63e 550 SUPERFAMILY SSF51569 25 314 7.87E-78 T 12-10-2018 TSC_c08430 c23b67bef698c002580535ac0d91d63e 550 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 32 48 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSC_c08430 c23b67bef698c002580535ac0d91d63e 550 SUPERFAMILY SSF110921 420 532 3.01E-13 T 12-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSC_c08430 c23b67bef698c002580535ac0d91d63e 550 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 25 538 1.5E-204 T 12-10-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 TSC_c08430 c23b67bef698c002580535ac0d91d63e 550 Gene3D G3DSA:1.10.238.260 305 401 6.0E-27 T 12-10-2018 TSC_c08430 c23b67bef698c002580535ac0d91d63e 550 SMART SM00917 394 537 6.8E-33 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSC_c08430 c23b67bef698c002580535ac0d91d63e 550 Pfam PF00682 HMGL-like 25 270 2.0E-40 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TSC_c05760 fa79748382c98f7100bfca4690f64d13 398 Pfam PF13458 Periplasmic binding protein 21 346 7.6E-57 T 12-10-2018 IPR028081 Leucine-binding protein domain TSC_c05760 fa79748382c98f7100bfca4690f64d13 398 SUPERFAMILY SSF53822 21 382 9.03E-55 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TSC_c05760 fa79748382c98f7100bfca4690f64d13 398 Gene3D G3DSA:3.40.50.2300 29 345 3.6E-127 T 12-10-2018 TSC_c05760 fa79748382c98f7100bfca4690f64d13 398 Gene3D G3DSA:3.40.50.2300 138 274 3.6E-127 T 12-10-2018 TSC_c21990 da8fbafa1105f87de51d57d78dac4121 274 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 5 266 44.96 T 12-10-2018 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 TSC_c21990 da8fbafa1105f87de51d57d78dac4121 274 Pfam PF02621 Menaquinone biosynthesis 6 260 6.2E-93 T 12-10-2018 IPR003773 Menaquinone biosynthesis enzyme TSC_c21990 da8fbafa1105f87de51d57d78dac4121 274 Gene3D G3DSA:3.40.190.10 8 261 2.4E-114 T 12-10-2018 TSC_c21990 da8fbafa1105f87de51d57d78dac4121 274 Gene3D G3DSA:3.40.190.10 82 174 2.4E-114 T 12-10-2018 TSC_c21990 da8fbafa1105f87de51d57d78dac4121 274 SUPERFAMILY SSF53850 6 265 1.68E-88 T 12-10-2018 TSC_c02240 d55820661c1a054455e5c9e9c4eae74a 88 Gene3D G3DSA:4.10.640.10 1 88 1.2E-36 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c02240 d55820661c1a054455e5c9e9c4eae74a 88 Pfam PF01084 Ribosomal protein S18 33 79 5.8E-23 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c02240 d55820661c1a054455e5c9e9c4eae74a 88 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 33 82 8.0E-21 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c02240 d55820661c1a054455e5c9e9c4eae74a 88 SUPERFAMILY SSF46911 11 84 2.22E-24 T 12-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c02240 d55820661c1a054455e5c9e9c4eae74a 88 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 14 84 20.535 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c02240 d55820661c1a054455e5c9e9c4eae74a 88 TIGRFAM TIGR00165 S18: ribosomal protein bS18 28 84 5.0E-22 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c02240 d55820661c1a054455e5c9e9c4eae74a 88 PRINTS PR00974 Ribosomal protein S18 family signature 49 56 6.3E-19 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c02240 d55820661c1a054455e5c9e9c4eae74a 88 PRINTS PR00974 Ribosomal protein S18 family signature 57 71 6.3E-19 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c02240 d55820661c1a054455e5c9e9c4eae74a 88 PRINTS PR00974 Ribosomal protein S18 family signature 71 81 6.3E-19 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c02240 d55820661c1a054455e5c9e9c4eae74a 88 PRINTS PR00974 Ribosomal protein S18 family signature 39 49 6.3E-19 T 12-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c19470 c395895bdd6c200bab133ac334ec48b6 514 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 378 468 4.6E-18 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TSC_c19470 c395895bdd6c200bab133ac334ec48b6 514 Gene3D G3DSA:3.40.50.620 14 231 1.1E-58 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c19470 c395895bdd6c200bab133ac334ec48b6 514 Pfam PF01171 PP-loop family 26 197 1.1E-43 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TSC_c19470 c395895bdd6c200bab133ac334ec48b6 514 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 13 302 22.912 T 12-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TSC_c19470 c395895bdd6c200bab133ac334ec48b6 514 SUPERFAMILY SSF82829 209 308 6.28E-7 T 12-10-2018 TSC_c19470 c395895bdd6c200bab133ac334ec48b6 514 SUPERFAMILY SSF53927 358 508 1.72E-33 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TSC_c19470 c395895bdd6c200bab133ac334ec48b6 514 Gene3D G3DSA:3.40.140.10 371 513 2.4E-35 T 12-10-2018 TSC_c19470 c395895bdd6c200bab133ac334ec48b6 514 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 26 202 1.1E-46 T 12-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 TSC_c19470 c395895bdd6c200bab133ac334ec48b6 514 SUPERFAMILY SSF52402 19 229 4.41E-52 T 12-10-2018 TSC_c19470 c395895bdd6c200bab133ac334ec48b6 514 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 427 459 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TSC_c24870 74973fbdcca45c3b5efa13ee3b846146 366 Gene3D G3DSA:2.40.37.10 13 354 7.3E-86 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TSC_c24870 74973fbdcca45c3b5efa13ee3b846146 366 TIGRFAM TIGR00492 alr: alanine racemase 11 355 2.1E-64 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSC_c24870 74973fbdcca45c3b5efa13ee3b846146 366 SUPERFAMILY SSF50621 221 363 8.02E-32 T 12-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 TSC_c24870 74973fbdcca45c3b5efa13ee3b846146 366 Pfam PF00842 Alanine racemase, C-terminal domain 233 355 6.2E-26 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSC_c24870 74973fbdcca45c3b5efa13ee3b846146 366 SUPERFAMILY SSF51419 16 232 1.44E-51 T 12-10-2018 IPR029066 PLP-binding barrel TSC_c24870 74973fbdcca45c3b5efa13ee3b846146 366 PRINTS PR00992 Alanine racemase signature 248 263 9.0E-40 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSC_c24870 74973fbdcca45c3b5efa13ee3b846146 366 PRINTS PR00992 Alanine racemase signature 338 351 9.0E-40 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSC_c24870 74973fbdcca45c3b5efa13ee3b846146 366 PRINTS PR00992 Alanine racemase signature 33 49 9.0E-40 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSC_c24870 74973fbdcca45c3b5efa13ee3b846146 366 PRINTS PR00992 Alanine racemase signature 265 280 9.0E-40 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSC_c24870 74973fbdcca45c3b5efa13ee3b846146 366 PRINTS PR00992 Alanine racemase signature 69 87 9.0E-40 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSC_c24870 74973fbdcca45c3b5efa13ee3b846146 366 PRINTS PR00992 Alanine racemase signature 285 302 9.0E-40 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSC_c24870 74973fbdcca45c3b5efa13ee3b846146 366 PRINTS PR00992 Alanine racemase signature 163 174 9.0E-40 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSC_c24870 74973fbdcca45c3b5efa13ee3b846146 366 PRINTS PR00992 Alanine racemase signature 130 142 9.0E-40 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSC_c24870 74973fbdcca45c3b5efa13ee3b846146 366 Pfam PF01168 Alanine racemase, N-terminal domain 16 225 2.6E-54 T 12-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSC_c24870 74973fbdcca45c3b5efa13ee3b846146 366 SMART SM01005 232 356 4.7E-32 T 12-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSC_c24870 74973fbdcca45c3b5efa13ee3b846146 366 Hamap MF_01201 Alanine racemase. 9 356 25.926 T 12-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 TSC_c24870 74973fbdcca45c3b5efa13ee3b846146 366 Gene3D G3DSA:3.20.20.10 18 220 7.3E-86 T 12-10-2018 IPR029066 PLP-binding barrel TSC_c11590 dd937278cd5bb5be5713565412aa096c 231 Gene3D G3DSA:3.90.850.10 1 225 5.9E-44 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSC_c11590 dd937278cd5bb5be5713565412aa096c 231 SUPERFAMILY SSF56529 3 215 3.92E-38 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSC_c19940 f35254c5f61e8ec148b4c7329d16ee0b 105 SUPERFAMILY SSF51182 23 103 5.16E-18 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TSC_c19940 f35254c5f61e8ec148b4c7329d16ee0b 105 Gene3D G3DSA:2.60.120.10 1 105 3.4E-25 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TSC_c19940 f35254c5f61e8ec148b4c7329d16ee0b 105 Pfam PF07883 Cupin domain 33 100 1.7E-15 T 12-10-2018 IPR013096 Cupin 2, conserved barrel TSC_c22640 ace71433b1987567d7dc2dbb012b1a32 193 PRINTS PR00097 Anthranilate synthase component II signature 3 17 6.1E-37 T 12-10-2018 TSC_c22640 ace71433b1987567d7dc2dbb012b1a32 193 PRINTS PR00097 Anthranilate synthase component II signature 166 179 6.1E-37 T 12-10-2018 TSC_c22640 ace71433b1987567d7dc2dbb012b1a32 193 PRINTS PR00097 Anthranilate synthase component II signature 75 86 6.1E-37 T 12-10-2018 TSC_c22640 ace71433b1987567d7dc2dbb012b1a32 193 PRINTS PR00097 Anthranilate synthase component II signature 100 108 6.1E-37 T 12-10-2018 TSC_c22640 ace71433b1987567d7dc2dbb012b1a32 193 PRINTS PR00097 Anthranilate synthase component II signature 120 132 6.1E-37 T 12-10-2018 TSC_c22640 ace71433b1987567d7dc2dbb012b1a32 193 PRINTS PR00097 Anthranilate synthase component II signature 48 57 6.1E-37 T 12-10-2018 TSC_c22640 ace71433b1987567d7dc2dbb012b1a32 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 166 179 2.6E-13 T 12-10-2018 TSC_c22640 ace71433b1987567d7dc2dbb012b1a32 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 75 86 2.6E-13 T 12-10-2018 TSC_c22640 ace71433b1987567d7dc2dbb012b1a32 193 PRINTS PR00096 Glutamine amidotransferase superfamily signature 48 57 2.6E-13 T 12-10-2018 TSC_c22640 ace71433b1987567d7dc2dbb012b1a32 193 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 188 2.9E-71 T 12-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSC_c22640 ace71433b1987567d7dc2dbb012b1a32 193 Gene3D G3DSA:3.40.50.880 1 189 5.3E-62 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c22640 ace71433b1987567d7dc2dbb012b1a32 193 Pfam PF00117 Glutamine amidotransferase class-I 4 187 7.6E-49 T 12-10-2018 IPR017926 Glutamine amidotransferase TSC_c22640 ace71433b1987567d7dc2dbb012b1a32 193 SUPERFAMILY SSF52317 1 189 2.71E-56 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c22640 ace71433b1987567d7dc2dbb012b1a32 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 45 59 3.5E-7 T 12-10-2018 TSC_c22640 ace71433b1987567d7dc2dbb012b1a32 193 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 75 91 3.5E-7 T 12-10-2018 TSC_c22940 68832d5b7483e95503467226a4ee7289 122 Gene3D G3DSA:3.40.1350.10 18 121 1.0E-21 T 12-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 TSC_c22940 68832d5b7483e95503467226a4ee7289 122 Hamap MF_00048 UPF0102 protein YraN [yraN]. 12 119 19.705 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 TSC_c22940 68832d5b7483e95503467226a4ee7289 122 Pfam PF02021 Uncharacterised protein family UPF0102 19 106 1.7E-20 T 12-10-2018 IPR003509 Uncharacterised protein family UPF0102 TSC_c22940 68832d5b7483e95503467226a4ee7289 122 SUPERFAMILY SSF52980 18 109 4.18E-17 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSC_c02650 1d01cf4fa83c1caf1a59cf7061c7490a 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 5 253 1.9E-64 T 12-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 TSC_c02650 1d01cf4fa83c1caf1a59cf7061c7490a 254 SUPERFAMILY SSF52096 2 253 6.89E-81 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSC_c02650 1d01cf4fa83c1caf1a59cf7061c7490a 254 Gene3D G3DSA:3.90.226.10 1 196 1.0E-74 T 12-10-2018 TSC_c02650 1d01cf4fa83c1caf1a59cf7061c7490a 254 Gene3D G3DSA:1.10.12.10 197 254 3.4E-26 T 12-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal TSC_c03360 75ff5cfc0fd630d38b3d224bcc1ef972 199 Gene3D G3DSA:1.20.910.10 11 198 1.3E-42 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 TSC_c03360 75ff5cfc0fd630d38b3d224bcc1ef972 199 SUPERFAMILY SSF48613 36 197 2.37E-34 T 12-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 TSC_c11540 cb21cba2437da79f8fc9fa994d5265c4 135 Gene3D G3DSA:1.20.1290.10 5 134 3.5E-27 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSC_c11540 cb21cba2437da79f8fc9fa994d5265c4 135 Pfam PF02627 Carboxymuconolactone decarboxylase family 43 124 1.3E-6 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSC_c11540 cb21cba2437da79f8fc9fa994d5265c4 135 SUPERFAMILY SSF69118 7 128 3.04E-16 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSC_c09630 3e4aefa5d68d0531552469d4d8844fb6 576 Gene3D G3DSA:3.40.50.10710 238 387 5.0E-177 T 12-10-2018 TSC_c09630 3e4aefa5d68d0531552469d4d8844fb6 576 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 31 573 1.3E-159 T 12-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 TSC_c09630 3e4aefa5d68d0531552469d4d8844fb6 576 Gene3D G3DSA:3.10.20.580 478 575 2.7E-38 T 12-10-2018 TSC_c09630 3e4aefa5d68d0531552469d4d8844fb6 576 Hamap MF_01491 Ribonuclease J [rnj]. 26 576 41.55 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 TSC_c09630 3e4aefa5d68d0531552469d4d8844fb6 576 Pfam PF12706 Beta-lactamase superfamily domain 86 196 9.8E-12 T 12-10-2018 IPR001279 Metallo-beta-lactamase TSC_c09630 3e4aefa5d68d0531552469d4d8844fb6 576 SMART SM00849 43 245 3.4E-14 T 12-10-2018 IPR001279 Metallo-beta-lactamase TSC_c09630 3e4aefa5d68d0531552469d4d8844fb6 576 Gene3D G3DSA:3.60.15.10 33 473 5.0E-177 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c09630 3e4aefa5d68d0531552469d4d8844fb6 576 SUPERFAMILY SSF56281 32 453 2.41E-83 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c09630 3e4aefa5d68d0531552469d4d8844fb6 576 PIRSF PIRSF004803 25 576 7.0E-222 T 12-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 TSC_c09630 3e4aefa5d68d0531552469d4d8844fb6 576 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 391 432 9.7E-6 T 12-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 SMART SM00464 15 207 2.5E-63 T 12-10-2018 IPR003111 Lon, substrate-binding domain TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 SUPERFAMILY SSF54211 611 786 8.34E-56 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 SMART SM00382 364 512 7.4E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 PIRSF PIRSF001174 3 790 0.0 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 Gene3D G3DSA:3.40.50.300 317 507 2.4E-66 T 12-10-2018 TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 Gene3D G3DSA:2.30.130.40 9 121 9.6E-29 T 12-10-2018 TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 SUPERFAMILY SSF88697 15 206 1.29E-38 T 12-10-2018 IPR015947 PUA-like superfamily TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 Gene3D G3DSA:3.30.230.10 609 799 1.8E-80 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 TIGRFAM TIGR00763 lon: endopeptidase La 18 787 4.8E-288 T 12-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 Hamap MF_01973 Lon protease [lon]. 16 788 70.455 T 12-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 368 506 1.0E-22 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 SUPERFAMILY SSF52540 314 600 3.74E-52 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 372 391 1.9E-49 T 12-10-2018 TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 719 738 1.9E-49 T 12-10-2018 TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 742 760 1.9E-49 T 12-10-2018 TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 611 627 1.9E-49 T 12-10-2018 TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 689 708 1.9E-49 T 12-10-2018 TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 15 206 2.0E-38 T 12-10-2018 IPR003111 Lon, substrate-binding domain TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 586 788 6.8E-92 T 12-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 Gene3D G3DSA:1.10.8.60 508 600 9.7E-32 T 12-10-2018 TSC_c09900 09daf0eaedec956642f1d519be997fa8 818 Gene3D G3DSA:1.20.58.1480 127 250 1.0E-37 T 12-10-2018 TSC_c24460 7bbfab4ee023c204b896595bdb34aa20 385 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 365 3.2E-140 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TSC_c24460 7bbfab4ee023c204b896595bdb34aa20 385 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 365 1.4E-145 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TSC_c24460 7bbfab4ee023c204b896595bdb34aa20 385 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 365 53.872 T 12-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TSC_c24460 7bbfab4ee023c204b896595bdb34aa20 385 Pfam PF01702 Queuine tRNA-ribosyltransferase 130 362 1.2E-84 T 12-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TSC_c24460 7bbfab4ee023c204b896595bdb34aa20 385 Gene3D G3DSA:3.20.20.105 1 371 7.9E-159 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TSC_c24460 7bbfab4ee023c204b896595bdb34aa20 385 SUPERFAMILY SSF51713 4 365 1.83E-147 T 12-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 TSC_c06050 a9e3f2b5ff10a03cf0587f70c799b7dd 119 Gene3D G3DSA:1.20.58.1610 2 119 3.7E-42 T 12-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06050 a9e3f2b5ff10a03cf0587f70c799b7dd 119 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 23 118 5.5E-31 T 12-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06050 a9e3f2b5ff10a03cf0587f70c799b7dd 119 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 3 119 17.916 T 12-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 TSC_c07150 9eb485ac8c0091dc57992b802dd82919 197 SUPERFAMILY SSF55821 8 195 8.55E-46 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TSC_c07150 9eb485ac8c0091dc57992b802dd82919 197 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 6 186 1.2E-39 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 TSC_c07150 9eb485ac8c0091dc57992b802dd82919 197 Pfam PF01300 Telomere recombination 15 183 4.8E-42 T 12-10-2018 IPR006070 YrdC-like domain GO:0003725 TSC_c07150 9eb485ac8c0091dc57992b802dd82919 197 Gene3D G3DSA:3.90.870.10 2 197 1.5E-52 T 12-10-2018 TSC_c03230 57c409d687c5ad4f5b43a7d8b4dc6f63 316 Gene3D G3DSA:3.90.226.10 1 315 2.7E-121 T 12-10-2018 TSC_c03230 57c409d687c5ad4f5b43a7d8b4dc6f63 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 194 203 3.9E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c03230 57c409d687c5ad4f5b43a7d8b4dc6f63 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 131 147 3.9E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c03230 57c409d687c5ad4f5b43a7d8b4dc6f63 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 166 179 3.9E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c03230 57c409d687c5ad4f5b43a7d8b4dc6f63 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 150 163 3.9E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c03230 57c409d687c5ad4f5b43a7d8b4dc6f63 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 85 96 3.9E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c03230 57c409d687c5ad4f5b43a7d8b4dc6f63 316 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 110 128 3.9E-45 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c03230 57c409d687c5ad4f5b43a7d8b4dc6f63 316 SUPERFAMILY SSF52096 4 313 1.88E-96 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSC_c03230 57c409d687c5ad4f5b43a7d8b4dc6f63 316 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 3 315 3.0E-135 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c03230 57c409d687c5ad4f5b43a7d8b4dc6f63 316 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 2 313 49.781 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c03230 57c409d687c5ad4f5b43a7d8b4dc6f63 316 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 3 145 1.1E-62 T 12-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c14820 030333ece7016cf022f1262e9bf15225 369 SUPERFAMILY SSF161098 198 355 7.98E-30 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c14820 030333ece7016cf022f1262e9bf15225 369 SUPERFAMILY SSF161098 56 176 1.7E-18 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c14820 030333ece7016cf022f1262e9bf15225 369 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 208 356 2.5E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c08040 35700324e6aa3411110b3440945454db 500 SUPERFAMILY SSF51445 5 499 4.14E-173 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TSC_c08040 35700324e6aa3411110b3440945454db 500 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 4 483 7.2E-111 T 12-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TSC_c08040 35700324e6aa3411110b3440945454db 500 Gene3D G3DSA:3.20.20.80 1 500 1.5E-220 T 12-10-2018 TSC_c08040 35700324e6aa3411110b3440945454db 500 Pfam PF02446 4-alpha-glucanotransferase 11 478 4.3E-162 T 12-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 TSC_c21600 706fa492699d08bdcfff7cd14f0986f0 798 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 477 791 1.5E-60 T 12-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 TSC_c21600 706fa492699d08bdcfff7cd14f0986f0 798 Gene3D G3DSA:3.50.30.10 358 467 1.7E-39 T 12-10-2018 TSC_c21600 706fa492699d08bdcfff7cd14f0986f0 798 Pfam PF00391 PEP-utilising enzyme, mobile domain 386 457 1.6E-25 T 12-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 TSC_c21600 706fa492699d08bdcfff7cd14f0986f0 798 Gene3D G3DSA:3.30.1490.20 1 193 2.7E-71 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSC_c21600 706fa492699d08bdcfff7cd14f0986f0 798 Gene3D G3DSA:3.30.470.20 194 357 6.1E-46 T 12-10-2018 TSC_c21600 706fa492699d08bdcfff7cd14f0986f0 798 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 4 791 0.0 T 12-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 TSC_c21600 706fa492699d08bdcfff7cd14f0986f0 798 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 416 427 - T 12-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 TSC_c21600 706fa492699d08bdcfff7cd14f0986f0 798 SUPERFAMILY SSF51621 463 792 4.97E-93 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSC_c21600 706fa492699d08bdcfff7cd14f0986f0 798 SUPERFAMILY SSF56059 1 387 8.24E-104 T 12-10-2018 TSC_c21600 706fa492699d08bdcfff7cd14f0986f0 798 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 696 714 - T 12-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 TSC_c21600 706fa492699d08bdcfff7cd14f0986f0 798 PIRSF PIRSF000854 1 796 0.0 T 12-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 TSC_c21600 706fa492699d08bdcfff7cd14f0986f0 798 SUPERFAMILY SSF52009 355 463 5.76E-33 T 12-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 TSC_c21600 706fa492699d08bdcfff7cd14f0986f0 798 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 16 345 3.2E-109 T 12-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 TSC_c21600 706fa492699d08bdcfff7cd14f0986f0 798 Gene3D G3DSA:3.20.20.60 480 791 9.9E-95 T 12-10-2018 TSC_c19790 780010be2a80ef96ddb7c8c805b4e49d 184 Pfam PF13808 DDE_Tnp_1-associated 5 86 2.3E-15 T 12-10-2018 IPR032806 H repeat-associated protein, N-terminal TSC_c02110 780010be2a80ef96ddb7c8c805b4e49d 184 Pfam PF13808 DDE_Tnp_1-associated 5 86 2.3E-15 T 12-10-2018 IPR032806 H repeat-associated protein, N-terminal TSC_p800010 780010be2a80ef96ddb7c8c805b4e49d 184 Pfam PF13808 DDE_Tnp_1-associated 5 86 2.3E-15 T 12-10-2018 IPR032806 H repeat-associated protein, N-terminal TSC_c08190 780010be2a80ef96ddb7c8c805b4e49d 184 Pfam PF13808 DDE_Tnp_1-associated 5 86 2.3E-15 T 12-10-2018 IPR032806 H repeat-associated protein, N-terminal TSC_c07700 99597c6cf9dc93e87044c7a36386c8ea 121 Pfam PF01909 Nucleotidyltransferase domain 12 68 2.6E-10 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSC_c07700 99597c6cf9dc93e87044c7a36386c8ea 121 Gene3D G3DSA:3.30.460.10 5 78 1.8E-15 T 12-10-2018 TSC_c07700 99597c6cf9dc93e87044c7a36386c8ea 121 SUPERFAMILY SSF81301 7 72 3.27E-16 T 12-10-2018 TSC_c01330 294f6e1974f4e114d14c209bf20842e8 669 Gene3D G3DSA:2.20.25.90 1 54 1.3E-7 T 12-10-2018 TSC_c01330 294f6e1974f4e114d14c209bf20842e8 669 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 3 49 3.9E-10 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c01330 294f6e1974f4e114d14c209bf20842e8 669 Pfam PF00384 Molybdopterin oxidoreductase 56 472 1.4E-62 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c01330 294f6e1974f4e114d14c209bf20842e8 669 Pfam PF01568 Molydopterin dinucleotide binding domain 549 660 1.6E-25 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSC_c01330 294f6e1974f4e114d14c209bf20842e8 669 Gene3D G3DSA:2.40.40.20 543 668 2.1E-28 T 12-10-2018 TSC_c01330 294f6e1974f4e114d14c209bf20842e8 669 SMART SM00926 1 55 5.1E-13 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c01330 294f6e1974f4e114d14c209bf20842e8 669 SUPERFAMILY SSF53706 3 559 5.89E-153 T 12-10-2018 TSC_c01330 294f6e1974f4e114d14c209bf20842e8 669 Gene3D G3DSA:3.40.228.10 133 359 1.3E-131 T 12-10-2018 TSC_c01330 294f6e1974f4e114d14c209bf20842e8 669 Gene3D G3DSA:3.40.50.740 67 477 1.3E-131 T 12-10-2018 TSC_c01330 294f6e1974f4e114d14c209bf20842e8 669 Gene3D G3DSA:3.30.2070.10 432 516 1.3E-131 T 12-10-2018 TSC_c01330 294f6e1974f4e114d14c209bf20842e8 669 SUPERFAMILY SSF50692 545 666 2.28E-33 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSC_c16570 ea73b8ae48ab908e9e8e3803b4e3570c 237 Pfam PF02163 Peptidase family M50 14 219 3.9E-24 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TSC_c19160 240c678f91bda5902dd1e9e7e691614a 450 SUPERFAMILY SSF48452 139 276 1.3E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c19160 240c678f91bda5902dd1e9e7e691614a 450 Gene3D G3DSA:1.25.40.10 209 406 1.8E-18 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c19160 240c678f91bda5902dd1e9e7e691614a 450 SUPERFAMILY SSF48452 252 384 1.66E-12 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c19160 240c678f91bda5902dd1e9e7e691614a 450 SUPERFAMILY SSF81901 7 240 2.22E-7 T 12-10-2018 TSC_c19160 240c678f91bda5902dd1e9e7e691614a 450 Pfam PF13181 Tetratricopeptide repeat 253 276 0.11 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c19160 240c678f91bda5902dd1e9e7e691614a 450 Pfam PF13432 Tetratricopeptide repeat 289 340 9.1E-5 T 12-10-2018 TSC_c19160 240c678f91bda5902dd1e9e7e691614a 450 SMART SM00028 283 316 140.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c19160 240c678f91bda5902dd1e9e7e691614a 450 SMART SM00028 209 242 11.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c19160 240c678f91bda5902dd1e9e7e691614a 450 SMART SM00028 353 385 430.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c19160 240c678f91bda5902dd1e9e7e691614a 450 SMART SM00028 247 280 50.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c19160 240c678f91bda5902dd1e9e7e691614a 450 SMART SM00028 101 131 460.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c19160 240c678f91bda5902dd1e9e7e691614a 450 SMART SM00028 319 352 1.9 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c19160 240c678f91bda5902dd1e9e7e691614a 450 SMART SM00028 134 167 28.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 Gene3D G3DSA:3.30.70.870 292 373 2.0E-35 T 12-10-2018 TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 155 1.8E-18 T 12-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 SUPERFAMILY SSF54980 405 502 7.67E-25 T 12-10-2018 IPR035647 EF-G domain III/V-like TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 Pfam PF03144 Elongation factor Tu domain 2 210 281 5.1E-10 T 12-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 Pfam PF00009 Elongation factor Tu GTP binding domain 7 186 1.1E-52 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 PRINTS PR00315 GTP-binding elongation factor signature 79 89 2.6E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 PRINTS PR00315 GTP-binding elongation factor signature 11 24 2.6E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 PRINTS PR00315 GTP-binding elongation factor signature 54 62 2.6E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 PRINTS PR00315 GTP-binding elongation factor signature 95 106 2.6E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 PRINTS PR00315 GTP-binding elongation factor signature 131 140 2.6E-14 T 12-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 Gene3D G3DSA:3.30.70.2570 488 562 2.0E-34 T 12-10-2018 IPR038363 LepA, C-terminal domain superfamily TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 SUPERFAMILY SSF54980 297 376 8.27E-19 T 12-10-2018 IPR035647 EF-G domain III/V-like TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 Gene3D G3DSA:2.40.30.10 191 291 1.7E-34 T 12-10-2018 TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 Gene3D G3DSA:3.30.70.3380 374 487 1.5E-45 T 12-10-2018 TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 Pfam PF00679 Elongation factor G C-terminus 404 492 1.5E-22 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 TIGRFAM TIGR01393 lepA: elongation factor 4 7 603 8.2E-296 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 290.322 T 12-10-2018 IPR006297 Elongation factor 4 GO:0005525 TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 47 62 - T 12-10-2018 IPR031157 Tr-type G domain, conserved site TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 SMART SM00838 404 495 3.6E-4 T 12-10-2018 IPR000640 Elongation factor EFG, domain V-like TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 Pfam PF06421 GTP-binding protein LepA C-terminus 496 602 6.2E-50 T 12-10-2018 IPR013842 GTP-binding protein LepA, C-terminal TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 Gene3D G3DSA:3.40.50.300 6 190 1.7E-78 T 12-10-2018 TSC_c08950 6e88dfd4612957e9a514d7ff399f7895 608 SUPERFAMILY SSF52540 4 226 2.82E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c03600 c9b1d0bffc0e88703747deaaa6eb33a6 139 Gene3D G3DSA:3.55.10.10 3 139 2.3E-37 T 12-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 TSC_c03600 c9b1d0bffc0e88703747deaaa6eb33a6 139 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 7 138 5.0E-57 T 12-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 TSC_c03600 c9b1d0bffc0e88703747deaaa6eb33a6 139 Pfam PF01951 Archease protein family (MTH1598/TM1083) 6 139 5.2E-35 T 12-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 TSC_c03600 c9b1d0bffc0e88703747deaaa6eb33a6 139 SUPERFAMILY SSF69819 4 139 6.28E-37 T 12-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 TSC_c05640 6389b7fe0c64bdec9692acb2bcfa9ff8 472 Gene3D G3DSA:1.10.1160.10 238 322 1.2E-34 T 12-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 TSC_c05640 6389b7fe0c64bdec9692acb2bcfa9ff8 472 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 8 19 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c05640 6389b7fe0c64bdec9692acb2bcfa9ff8 472 SUPERFAMILY SSF52374 1 300 2.06E-113 T 12-10-2018 TSC_c05640 6389b7fe0c64bdec9692acb2bcfa9ff8 472 Gene3D G3DSA:3.40.50.620 4 235 1.5E-103 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c05640 6389b7fe0c64bdec9692acb2bcfa9ff8 472 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 1 467 32.007 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TSC_c05640 6389b7fe0c64bdec9692acb2bcfa9ff8 472 PRINTS PR00987 Glutamyl-tRNA synthetase signature 185 195 3.1E-21 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSC_c05640 6389b7fe0c64bdec9692acb2bcfa9ff8 472 PRINTS PR00987 Glutamyl-tRNA synthetase signature 5 17 3.1E-21 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSC_c05640 6389b7fe0c64bdec9692acb2bcfa9ff8 472 PRINTS PR00987 Glutamyl-tRNA synthetase signature 34 47 3.1E-21 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSC_c05640 6389b7fe0c64bdec9692acb2bcfa9ff8 472 PRINTS PR00987 Glutamyl-tRNA synthetase signature 19 30 3.1E-21 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSC_c05640 6389b7fe0c64bdec9692acb2bcfa9ff8 472 PRINTS PR00987 Glutamyl-tRNA synthetase signature 201 209 3.1E-21 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSC_c05640 6389b7fe0c64bdec9692acb2bcfa9ff8 472 Gene3D G3DSA:3.90.800.10 71 186 1.5E-103 T 12-10-2018 TSC_c05640 6389b7fe0c64bdec9692acb2bcfa9ff8 472 Gene3D G3DSA:1.10.8.70 323 370 1.2E-24 T 12-10-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 TSC_c05640 6389b7fe0c64bdec9692acb2bcfa9ff8 472 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 2 465 1.2E-141 T 12-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TSC_c05640 6389b7fe0c64bdec9692acb2bcfa9ff8 472 SUPERFAMILY SSF48163 306 467 6.67E-48 T 12-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TSC_c05640 6389b7fe0c64bdec9692acb2bcfa9ff8 472 Gene3D G3DSA:1.10.10.350 371 468 1.7E-32 T 12-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 TSC_c05640 6389b7fe0c64bdec9692acb2bcfa9ff8 472 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 2 312 5.5E-110 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 TSC_c01790 93449a64a89c58ab9d2a37ca85718214 229 Gene3D G3DSA:3.40.50.790 68 160 8.8E-89 T 12-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich TSC_c01790 93449a64a89c58ab9d2a37ca85718214 229 PIRSF PIRSF002155 1 228 4.3E-85 T 12-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c01790 93449a64a89c58ab9d2a37ca85718214 229 Gene3D G3DSA:3.30.190.20 23 225 8.8E-89 T 12-10-2018 TSC_c01790 93449a64a89c58ab9d2a37ca85718214 229 SUPERFAMILY SSF56808 6 227 1.44E-84 T 12-10-2018 IPR023674 Ribosomal protein L1-like TSC_c01790 93449a64a89c58ab9d2a37ca85718214 229 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 1.8E-99 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 TSC_c01790 93449a64a89c58ab9d2a37ca85718214 229 Pfam PF00687 Ribosomal protein L1p/L10e family 31 221 6.7E-54 T 12-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein TSC_c01790 93449a64a89c58ab9d2a37ca85718214 229 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 41.051 T 12-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 TSC_c01790 93449a64a89c58ab9d2a37ca85718214 229 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 140 - T 12-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c06470 74720cacf203ff2a4dbab3ba0c7d7e86 300 Gene3D G3DSA:2.60.40.10 19 109 9.0E-13 T 12-10-2018 IPR013783 Immunoglobulin-like fold TSC_c06470 74720cacf203ff2a4dbab3ba0c7d7e86 300 ProSitePatterns PS00018 EF-hand calcium-binding domain. 250 262 - T 12-10-2018 IPR018247 EF-Hand 1, calcium-binding site TSC_c08230 da3d874ea049f974616c806c383c125e 244 Pfam PF01728 FtsJ-like methyltransferase 56 234 9.0E-21 T 12-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 TSC_c08230 da3d874ea049f974616c806c383c125e 244 Gene3D G3DSA:3.10.290.10 1 58 6.8E-22 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TSC_c08230 da3d874ea049f974616c806c383c125e 244 SMART SM00363 1 65 7.7E-16 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c08230 da3d874ea049f974616c806c383c125e 244 Gene3D G3DSA:3.40.50.150 59 239 3.1E-67 T 12-10-2018 TSC_c08230 da3d874ea049f974616c806c383c125e 244 Pfam PF01479 S4 domain 1 48 9.8E-15 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c08230 da3d874ea049f974616c806c383c125e 244 PIRSF PIRSF005578 1 239 1.1E-91 T 12-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 TSC_c08230 da3d874ea049f974616c806c383c125e 244 SUPERFAMILY SSF55174 2 66 2.21E-14 T 12-10-2018 TSC_c08230 da3d874ea049f974616c806c383c125e 244 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 2 227 1.9E-68 T 12-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 TSC_c08230 da3d874ea049f974616c806c383c125e 244 SUPERFAMILY SSF53335 54 232 1.38E-28 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c02960 8ef5dc4b7d07d9bb59089121c4d67e61 386 SUPERFAMILY SSF53756 7 378 5.07E-93 T 12-10-2018 TSC_c02960 8ef5dc4b7d07d9bb59089121c4d67e61 386 Pfam PF00534 Glycosyl transferases group 1 194 357 3.9E-38 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TSC_c02960 8ef5dc4b7d07d9bb59089121c4d67e61 386 Gene3D G3DSA:3.40.50.2000 178 363 5.4E-83 T 12-10-2018 TSC_c02960 8ef5dc4b7d07d9bb59089121c4d67e61 386 Pfam PF13439 Glycosyltransferase Family 4 18 182 1.7E-19 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSC_c02960 8ef5dc4b7d07d9bb59089121c4d67e61 386 Gene3D G3DSA:3.40.50.2000 27 376 5.4E-83 T 12-10-2018 TSC_c08050 2b31456619bba69466152ff952ccb108 288 Gene3D G3DSA:3.40.50.261 123 288 6.1E-68 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSC_c08050 2b31456619bba69466152ff952ccb108 288 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 287 41.567 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSC_c08050 2b31456619bba69466152ff952ccb108 288 Pfam PF02629 CoA binding domain 6 98 3.9E-32 T 12-10-2018 IPR003781 CoA-binding GO:0048037 TSC_c08050 2b31456619bba69466152ff952ccb108 288 SUPERFAMILY SSF51735 2 120 1.73E-41 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c08050 2b31456619bba69466152ff952ccb108 288 Pfam PF00549 CoA-ligase 150 268 1.7E-15 T 12-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSC_c08050 2b31456619bba69466152ff952ccb108 288 Gene3D G3DSA:3.40.50.720 1 122 3.4E-50 T 12-10-2018 TSC_c08050 2b31456619bba69466152ff952ccb108 288 SUPERFAMILY SSF52210 122 284 1.57E-51 T 12-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 TSC_c08050 2b31456619bba69466152ff952ccb108 288 PIRSF PIRSF001553 1 288 2.9E-131 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSC_c08050 2b31456619bba69466152ff952ccb108 288 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 151 180 - T 12-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site TSC_c08050 2b31456619bba69466152ff952ccb108 288 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 235 248 - T 12-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site TSC_c08050 2b31456619bba69466152ff952ccb108 288 SMART SM00881 3 99 1.1E-37 T 12-10-2018 IPR003781 CoA-binding GO:0048037 TSC_c08050 2b31456619bba69466152ff952ccb108 288 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 2 287 1.1E-128 T 12-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 TSC_c08050 2b31456619bba69466152ff952ccb108 288 PRINTS PR01798 Succinyl-CoA synthase signature 176 194 7.7E-33 T 12-10-2018 TSC_c08050 2b31456619bba69466152ff952ccb108 288 PRINTS PR01798 Succinyl-CoA synthase signature 207 220 7.7E-33 T 12-10-2018 TSC_c08050 2b31456619bba69466152ff952ccb108 288 PRINTS PR01798 Succinyl-CoA synthase signature 81 98 7.7E-33 T 12-10-2018 TSC_c08050 2b31456619bba69466152ff952ccb108 288 PRINTS PR01798 Succinyl-CoA synthase signature 239 256 7.7E-33 T 12-10-2018 TSC_c14150 857b77c43ae0d094e0c794bf84f8954e 282 Pfam PF01040 UbiA prenyltransferase family 20 262 3.8E-53 T 12-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 TSC_c14150 857b77c43ae0d094e0c794bf84f8954e 282 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 3 280 7.8E-101 T 12-10-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related TSC_c14150 857b77c43ae0d094e0c794bf84f8954e 282 Gene3D G3DSA:1.20.120.1780 161 282 4.9E-34 T 12-10-2018 TSC_c14150 857b77c43ae0d094e0c794bf84f8954e 282 Gene3D G3DSA:1.10.357.140 10 160 2.4E-51 T 12-10-2018 TSC_c17880 fc8ff5ac75218b6266876da2e56b180f 227 SUPERFAMILY SSF100950 5 179 1.15E-41 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TSC_c17880 fc8ff5ac75218b6266876da2e56b180f 227 Gene3D G3DSA:3.30.70.260 135 205 5.3E-24 T 12-10-2018 TSC_c17880 fc8ff5ac75218b6266876da2e56b180f 227 SUPERFAMILY SSF75445 131 208 4.45E-21 T 12-10-2018 TSC_c17880 fc8ff5ac75218b6266876da2e56b180f 227 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 55 219 1.2E-57 T 12-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TSC_c17880 fc8ff5ac75218b6266876da2e56b180f 227 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 9 222 4.4E-73 T 12-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TSC_c17880 fc8ff5ac75218b6266876da2e56b180f 227 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 5 225 30.734 T 12-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 TSC_c17880 fc8ff5ac75218b6266876da2e56b180f 227 Gene3D G3DSA:3.40.50.1360 1 134 1.4E-52 T 12-10-2018 TSC_c08660 d19933feb6c648e4f79e1d2e0bf8af27 632 Gene3D G3DSA:3.30.300.30 505 631 1.7E-26 T 12-10-2018 TSC_c08660 d19933feb6c648e4f79e1d2e0bf8af27 632 ProSitePatterns PS00455 Putative AMP-binding domain signature. 250 261 - T 12-10-2018 IPR020845 AMP-binding, conserved site TSC_c08660 d19933feb6c648e4f79e1d2e0bf8af27 632 Pfam PF13193 AMP-binding enzyme C-terminal domain 517 595 1.9E-21 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSC_c08660 d19933feb6c648e4f79e1d2e0bf8af27 632 SUPERFAMILY SSF56801 20 626 1.83E-149 T 12-10-2018 TSC_c08660 d19933feb6c648e4f79e1d2e0bf8af27 632 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 29 81 2.8E-8 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 TSC_c08660 d19933feb6c648e4f79e1d2e0bf8af27 632 Pfam PF00501 AMP-binding enzyme 84 508 1.7E-73 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSC_c08660 d19933feb6c648e4f79e1d2e0bf8af27 632 Gene3D G3DSA:3.40.50.12780 76 504 8.7E-87 T 12-10-2018 TSC_c22620 7cdde7521293f9cdd8525ee90cffcc09 408 Gene3D G3DSA:3.40.440.10 6 248 5.5E-88 T 12-10-2018 TSC_c22620 7cdde7521293f9cdd8525ee90cffcc09 408 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 402 2.2E-137 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TSC_c22620 7cdde7521293f9cdd8525ee90cffcc09 408 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 12-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TSC_c22620 7cdde7521293f9cdd8525ee90cffcc09 408 SUPERFAMILY SSF52540 2 402 1.02E-141 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c22620 7cdde7521293f9cdd8525ee90cffcc09 408 Pfam PF00709 Adenylosuccinate synthetase 4 401 6.4E-153 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TSC_c22620 7cdde7521293f9cdd8525ee90cffcc09 408 Gene3D G3DSA:3.90.170.10 255 405 8.2E-53 T 12-10-2018 TSC_c22620 7cdde7521293f9cdd8525ee90cffcc09 408 Gene3D G3DSA:1.10.300.10 99 189 5.5E-88 T 12-10-2018 TSC_c22620 7cdde7521293f9cdd8525ee90cffcc09 408 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 408 155.385 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TSC_c22620 7cdde7521293f9cdd8525ee90cffcc09 408 SMART SM00788 3 403 5.6E-201 T 12-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 TSC_c23100 98bc9bfb995e1400fb09d97a05a4a7d5 154 Gene3D G3DSA:2.60.40.790 13 152 4.0E-34 T 12-10-2018 IPR008978 HSP20-like chaperone TSC_c23100 98bc9bfb995e1400fb09d97a05a4a7d5 154 SUPERFAMILY SSF49764 35 152 1.88E-33 T 12-10-2018 IPR008978 HSP20-like chaperone TSC_c23100 98bc9bfb995e1400fb09d97a05a4a7d5 154 Pfam PF00011 Hsp20/alpha crystallin family 52 150 1.0E-20 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain TSC_c00100 99d794c6f62fa27bd5739483704d5470 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 2.1E-50 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSC_c00100 99d794c6f62fa27bd5739483704d5470 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 2.1E-50 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSC_c00100 99d794c6f62fa27bd5739483704d5470 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 2.1E-50 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSC_c00100 99d794c6f62fa27bd5739483704d5470 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 2.1E-50 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSC_c00100 99d794c6f62fa27bd5739483704d5470 137 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 2.1E-50 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSC_c00100 99d794c6f62fa27bd5739483704d5470 137 SMART SM00562 1 137 2.1E-88 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSC_c00100 99d794c6f62fa27bd5739483704d5470 137 Gene3D G3DSA:3.30.70.141 1 137 1.5E-63 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSC_c00100 99d794c6f62fa27bd5739483704d5470 137 SUPERFAMILY SSF54919 1 136 4.32E-60 T 12-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSC_c00100 99d794c6f62fa27bd5739483704d5470 137 Pfam PF00334 Nucleoside diphosphate kinase 2 135 1.3E-59 T 12-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSC_c00100 99d794c6f62fa27bd5739483704d5470 137 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 37.872 T 12-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSC_c08680 0aa6c785b2025e02576b80e4df4ab713 224 SMART SM00849 8 187 7.4E-11 T 12-10-2018 IPR001279 Metallo-beta-lactamase TSC_c08680 0aa6c785b2025e02576b80e4df4ab713 224 Gene3D G3DSA:3.60.15.10 2 222 5.2E-72 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c08680 0aa6c785b2025e02576b80e4df4ab713 224 Pfam PF13483 Beta-lactamase superfamily domain 3 187 1.5E-22 T 12-10-2018 TSC_c08680 0aa6c785b2025e02576b80e4df4ab713 224 SUPERFAMILY SSF56281 1 219 2.44E-40 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c08680 0aa6c785b2025e02576b80e4df4ab713 224 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 2 223 36.782 T 12-10-2018 IPR022877 Protein of unknown funcion UPF0173 TSC_c02720 175c86d9ed85ded737eaafac8bc79376 473 SUPERFAMILY SSF52743 169 469 1.07E-84 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TSC_c02720 175c86d9ed85ded737eaafac8bc79376 473 PRINTS PR00723 Subtilisin serine protease family (S8) signature 401 417 9.5E-23 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TSC_c02720 175c86d9ed85ded737eaafac8bc79376 473 PRINTS PR00723 Subtilisin serine protease family (S8) signature 237 250 9.5E-23 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TSC_c02720 175c86d9ed85ded737eaafac8bc79376 473 PRINTS PR00723 Subtilisin serine protease family (S8) signature 186 205 9.5E-23 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TSC_c02720 175c86d9ed85ded737eaafac8bc79376 473 Pfam PF00082 Subtilase family 186 459 5.3E-53 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TSC_c02720 175c86d9ed85ded737eaafac8bc79376 473 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 241 251 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TSC_c02720 175c86d9ed85ded737eaafac8bc79376 473 Gene3D G3DSA:3.40.50.200 160 470 6.2E-92 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TSC_c02720 175c86d9ed85ded737eaafac8bc79376 473 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 402 412 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TSC_c09260 62c5cd719619f599fdaab10b29d3c7f3 551 SUPERFAMILY SSF51703 4 545 4.51E-216 T 12-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSC_c09260 62c5cd719619f599fdaab10b29d3c7f3 551 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 26 549 1.2E-232 T 12-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSC_c09260 62c5cd719619f599fdaab10b29d3c7f3 551 Gene3D G3DSA:3.20.20.240 1 551 2.3E-249 T 12-10-2018 TSC_c09260 62c5cd719619f599fdaab10b29d3c7f3 551 Pfam PF01642 Methylmalonyl-CoA mutase 27 543 3.1E-226 T 12-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSC_c08440 81da980768a13d1392cd1e5f5bcec2c9 177 Gene3D G3DSA:3.90.1570.10 2 164 5.3E-14 T 12-10-2018 TSC_c08440 81da980768a13d1392cd1e5f5bcec2c9 177 Pfam PF05685 Putative restriction endonuclease 10 173 2.3E-34 T 12-10-2018 IPR008538 Domain of unknown function DUF820 TSC_c08440 81da980768a13d1392cd1e5f5bcec2c9 177 SUPERFAMILY SSF52980 6 172 6.97E-18 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSC_c25030 bc77a8004d2dd41abf91fe34742e3bba 270 SMART SM00470 24 113 4.0E-38 T 12-10-2018 IPR003115 ParB/Sulfiredoxin TSC_c25030 bc77a8004d2dd41abf91fe34742e3bba 270 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 21 187 2.3E-55 T 12-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 TSC_c25030 bc77a8004d2dd41abf91fe34742e3bba 270 Pfam PF02195 ParB-like nuclease domain 26 112 8.0E-29 T 12-10-2018 IPR003115 ParB/Sulfiredoxin TSC_c25030 bc77a8004d2dd41abf91fe34742e3bba 270 SUPERFAMILY SSF110849 24 115 1.07E-30 T 12-10-2018 IPR036086 ParB/Sulfiredoxin superfamily TSC_c25030 bc77a8004d2dd41abf91fe34742e3bba 270 SUPERFAMILY SSF109709 105 212 7.85E-36 T 12-10-2018 TSC_c25030 bc77a8004d2dd41abf91fe34742e3bba 270 Gene3D G3DSA:1.10.10.2830 100 212 2.0E-45 T 12-10-2018 TSC_c25030 bc77a8004d2dd41abf91fe34742e3bba 270 Gene3D G3DSA:3.90.1530.30 37 99 1.3E-30 T 12-10-2018 TSC_c12020 eab6c249b66036fb716b8db160cdc025 530 Gene3D G3DSA:3.60.20.40 353 530 7.4E-59 T 12-10-2018 TSC_c12020 eab6c249b66036fb716b8db160cdc025 530 Gene3D G3DSA:1.10.246.130 245 352 1.0E-24 T 12-10-2018 TSC_c12020 eab6c249b66036fb716b8db160cdc025 530 Pfam PF01019 Gamma-glutamyltranspeptidase 36 525 2.2E-144 T 12-10-2018 TSC_c12020 eab6c249b66036fb716b8db160cdc025 530 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 371 389 1.6E-40 T 12-10-2018 TSC_c12020 eab6c249b66036fb716b8db160cdc025 530 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 43 68 1.6E-40 T 12-10-2018 TSC_c12020 eab6c249b66036fb716b8db160cdc025 530 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 426 443 1.6E-40 T 12-10-2018 TSC_c12020 eab6c249b66036fb716b8db160cdc025 530 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 126 145 1.6E-40 T 12-10-2018 TSC_c12020 eab6c249b66036fb716b8db160cdc025 530 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 108 126 1.6E-40 T 12-10-2018 TSC_c12020 eab6c249b66036fb716b8db160cdc025 530 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 402 417 1.6E-40 T 12-10-2018 TSC_c12020 eab6c249b66036fb716b8db160cdc025 530 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 258 277 1.6E-40 T 12-10-2018 TSC_c12020 eab6c249b66036fb716b8db160cdc025 530 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 229 245 1.6E-40 T 12-10-2018 TSC_c12020 eab6c249b66036fb716b8db160cdc025 530 SUPERFAMILY SSF56235 3 530 2.12E-166 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSC_c19130 c34a1ce9f71ad52b79102e6c67bd303f 261 Pfam PF02548 Ketopantoate hydroxymethyltransferase 4 256 2.0E-103 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TSC_c19130 c34a1ce9f71ad52b79102e6c67bd303f 261 Gene3D G3DSA:3.20.20.60 2 261 2.7E-108 T 12-10-2018 TSC_c19130 c34a1ce9f71ad52b79102e6c67bd303f 261 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 13 261 8.0E-101 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TSC_c19130 c34a1ce9f71ad52b79102e6c67bd303f 261 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 3 261 42.685 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TSC_c19130 c34a1ce9f71ad52b79102e6c67bd303f 261 PIRSF PIRSF000388 1 261 2.0E-105 T 12-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 TSC_c19130 c34a1ce9f71ad52b79102e6c67bd303f 261 SUPERFAMILY SSF51621 5 261 1.65E-99 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSC_c07190 9cc4235ce39c92b26b84c6780b0c82e4 311 SMART SM00267 150 310 1.1E-54 T 12-10-2018 IPR000160 GGDEF domain TSC_c07190 9cc4235ce39c92b26b84c6780b0c82e4 311 Gene3D G3DSA:3.30.70.270 157 310 6.2E-53 T 12-10-2018 TSC_c07190 9cc4235ce39c92b26b84c6780b0c82e4 311 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 159 308 1.4E-44 T 12-10-2018 IPR000160 GGDEF domain TSC_c07190 9cc4235ce39c92b26b84c6780b0c82e4 311 Pfam PF00990 Diguanylate cyclase, GGDEF domain 165 306 2.2E-42 T 12-10-2018 IPR000160 GGDEF domain TSC_c07190 9cc4235ce39c92b26b84c6780b0c82e4 311 SUPERFAMILY SSF55073 166 308 3.69E-46 T 12-10-2018 IPR029787 Nucleotide cyclase TSC_p800090 94eb24c77828e14fd9156556d90b8105 347 SUPERFAMILY SSF51395 2 337 9.02E-118 T 12-10-2018 TSC_p800090 94eb24c77828e14fd9156556d90b8105 347 Gene3D G3DSA:3.20.20.70 1 347 5.7E-131 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_p800090 94eb24c77828e14fd9156556d90b8105 347 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 2 332 5.4E-70 T 12-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 TSC_c20630 f73b00a77061320f6f66f5b627910946 471 SMART SM00471 256 394 7.2E-13 T 12-10-2018 IPR003607 HD/PDEase domain TSC_c20630 f73b00a77061320f6f66f5b627910946 471 SUPERFAMILY SSF109604 249 424 5.65E-36 T 12-10-2018 TSC_c20630 f73b00a77061320f6f66f5b627910946 471 Gene3D G3DSA:1.10.3210.10 235 429 1.5E-67 T 12-10-2018 TSC_c20630 f73b00a77061320f6f66f5b627910946 471 Pfam PF01966 HD domain 263 385 7.8E-21 T 12-10-2018 IPR006674 HD domain TSC_c14460 22de9f9eab079e5db79f9b1381bf01ad 428 Gene3D G3DSA:3.40.1390.10 8 83 1.1E-14 T 12-10-2018 TSC_c14460 22de9f9eab079e5db79f9b1381bf01ad 428 Pfam PF01225 Mur ligase family, catalytic domain 34 76 1.7E-8 T 12-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 TSC_c14460 22de9f9eab079e5db79f9b1381bf01ad 428 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 34 425 7.1E-90 T 12-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSC_c14460 22de9f9eab079e5db79f9b1381bf01ad 428 SUPERFAMILY SSF53623 103 295 3.92E-28 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSC_c14460 22de9f9eab079e5db79f9b1381bf01ad 428 Gene3D G3DSA:3.40.1190.10 84 296 3.6E-37 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSC_c14460 22de9f9eab079e5db79f9b1381bf01ad 428 Gene3D G3DSA:3.90.190.20 299 428 3.5E-33 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSC_c14460 22de9f9eab079e5db79f9b1381bf01ad 428 Pfam PF02875 Mur ligase family, glutamate ligase domain 300 377 3.2E-13 T 12-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 TSC_c14460 22de9f9eab079e5db79f9b1381bf01ad 428 SUPERFAMILY SSF53244 300 425 9.52E-30 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSC_c14460 22de9f9eab079e5db79f9b1381bf01ad 428 SUPERFAMILY SSF63418 10 97 1.83E-18 T 12-10-2018 IPR035911 MurE/MurF, N-terminal TSC_c14460 22de9f9eab079e5db79f9b1381bf01ad 428 Pfam PF08245 Mur ligase middle domain 107 279 1.4E-16 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TSC_c17940 f39fe52c9d6f687c6000f27ff1c649e4 266 SUPERFAMILY SSF69796 2 220 1.83E-72 T 12-10-2018 IPR036098 Thymidylate synthase ThyX superfamily GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TSC_c17940 f39fe52c9d6f687c6000f27ff1c649e4 266 Pfam PF02511 Thymidylate synthase complementing protein 12 205 2.0E-58 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TSC_c17940 f39fe52c9d6f687c6000f27ff1c649e4 266 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 10 210 1.2E-64 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TSC_c17940 f39fe52c9d6f687c6000f27ff1c649e4 266 Gene3D G3DSA:3.30.1360.170 1 226 8.0E-81 T 12-10-2018 TSC_c17940 f39fe52c9d6f687c6000f27ff1c649e4 266 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 6 219 31.697 T 12-10-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00670+2.1.1.148|MetaCyc: PWY-6545 TSC_c20220 e71f4df5b7d29788c25402a198ecce9f 290 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 149 288 3.1E-25 T 12-10-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 TSC_c20220 e71f4df5b7d29788c25402a198ecce9f 290 Gene3D G3DSA:3.40.50.10490 142 274 3.5E-61 T 12-10-2018 TSC_c20220 e71f4df5b7d29788c25402a198ecce9f 290 SUPERFAMILY SSF53697 5 283 4.3E-53 T 12-10-2018 TSC_c20220 e71f4df5b7d29788c25402a198ecce9f 290 Gene3D G3DSA:3.40.50.10920 16 141 2.0E-56 T 12-10-2018 TSC_c11520 f11d1cf8cd2480a1af75f028aa2c2531 396 Gene3D G3DSA:3.40.50.2300 36 366 1.5E-109 T 12-10-2018 TSC_c11520 f11d1cf8cd2480a1af75f028aa2c2531 396 Gene3D G3DSA:3.40.50.2300 153 378 1.5E-109 T 12-10-2018 TSC_c11520 f11d1cf8cd2480a1af75f028aa2c2531 396 SUPERFAMILY SSF53822 35 373 7.95E-91 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TSC_c11520 f11d1cf8cd2480a1af75f028aa2c2531 396 Pfam PF13458 Periplasmic binding protein 35 373 4.6E-76 T 12-10-2018 IPR028081 Leucine-binding protein domain TSC_c18780 4292878457dc4c0f8817c811dda00cf7 620 Gene3D G3DSA:3.60.9.10 3 210 8.2E-74 T 12-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSC_c18780 4292878457dc4c0f8817c811dda00cf7 620 SUPERFAMILY SSF48310 235 617 1.03E-100 T 12-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSC_c18780 4292878457dc4c0f8817c811dda00cf7 620 SMART SM00790 5 207 1.5E-105 T 12-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSC_c18780 4292878457dc4c0f8817c811dda00cf7 620 Gene3D G3DSA:1.10.569.10 241 430 6.0E-111 T 12-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 TSC_c18780 4292878457dc4c0f8817c811dda00cf7 620 SUPERFAMILY SSF56228 4 209 1.28E-66 T 12-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily TSC_c18780 4292878457dc4c0f8817c811dda00cf7 620 Gene3D G3DSA:1.10.599.10 240 613 6.0E-111 T 12-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 TSC_c18780 4292878457dc4c0f8817c811dda00cf7 620 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 233 613 1.1E-105 T 12-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSC_c18780 4292878457dc4c0f8817c811dda00cf7 620 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 8 204 5.9E-68 T 12-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 TSC_c07560 049358d6298b0db650ab9a0c4fe175ca 352 Gene3D G3DSA:3.40.190.10 136 348 9.2E-109 T 12-10-2018 TSC_c07560 049358d6298b0db650ab9a0c4fe175ca 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 36 52 5.7E-41 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c07560 049358d6298b0db650ab9a0c4fe175ca 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 298 324 5.7E-41 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c07560 049358d6298b0db650ab9a0c4fe175ca 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 96 109 5.7E-41 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c07560 049358d6298b0db650ab9a0c4fe175ca 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 127 143 5.7E-41 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c07560 049358d6298b0db650ab9a0c4fe175ca 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 253 272 5.7E-41 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c07560 049358d6298b0db650ab9a0c4fe175ca 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 80 94 5.7E-41 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c07560 049358d6298b0db650ab9a0c4fe175ca 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 171 190 5.7E-41 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c07560 049358d6298b0db650ab9a0c4fe175ca 352 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 52 73 5.7E-41 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c07560 049358d6298b0db650ab9a0c4fe175ca 352 Gene3D G3DSA:3.40.190.10 35 320 9.2E-109 T 12-10-2018 TSC_c07560 049358d6298b0db650ab9a0c4fe175ca 352 PIRSF PIRSF019574 1 352 1.0E-102 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c07560 049358d6298b0db650ab9a0c4fe175ca 352 SUPERFAMILY SSF53850 30 350 1.05E-84 T 12-10-2018 TSC_c07560 049358d6298b0db650ab9a0c4fe175ca 352 Pfam PF13416 Bacterial extracellular solute-binding protein 46 318 1.5E-34 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSC_c17340 16134de809ccb7de92b172cbd8335d46 427 Pfam PF00512 His Kinase A (phospho-acceptor) domain 216 275 5.3E-10 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c17340 16134de809ccb7de92b172cbd8335d46 427 Gene3D G3DSA:3.30.565.10 279 424 4.6E-33 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c17340 16134de809ccb7de92b172cbd8335d46 427 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 316 419 7.4E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c17340 16134de809ccb7de92b172cbd8335d46 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 350 364 9.2E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c17340 16134de809ccb7de92b172cbd8335d46 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 368 378 9.2E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c17340 16134de809ccb7de92b172cbd8335d46 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 401 9.2E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c17340 16134de809ccb7de92b172cbd8335d46 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 406 419 9.2E-17 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c17340 16134de809ccb7de92b172cbd8335d46 427 SUPERFAMILY SSF55874 280 421 5.89E-31 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c17340 16134de809ccb7de92b172cbd8335d46 427 SUPERFAMILY SSF47384 197 275 2.94E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSC_c17340 16134de809ccb7de92b172cbd8335d46 427 Gene3D G3DSA:1.10.287.130 163 278 1.4E-18 T 12-10-2018 TSC_c17340 16134de809ccb7de92b172cbd8335d46 427 SMART SM00387 316 422 1.5E-29 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c17340 16134de809ccb7de92b172cbd8335d46 427 SMART SM00388 214 277 2.3E-9 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c08530 54d821293ef1347e4a1e9d9ebabb99ea 227 TIGRFAM TIGR04001 thiol_BshB1: bacillithiol biosynthesis deacetylase BshB1 2 216 5.8E-66 T 12-10-2018 IPR023842 Bacillithiol biosynthesis deacetylase, BshB1 GO:0019213|GO:0071793 TSC_c08530 54d821293ef1347e4a1e9d9ebabb99ea 227 Gene3D G3DSA:3.40.50.10320 1 227 1.5E-91 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TSC_c08530 54d821293ef1347e4a1e9d9ebabb99ea 227 SUPERFAMILY SSF102588 3 222 4.05E-58 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TSC_c08530 54d821293ef1347e4a1e9d9ebabb99ea 227 Pfam PF02585 GlcNAc-PI de-N-acetylase 5 121 4.3E-22 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TSC_c02830 0b06fd7dab820ea0ec0b5b0130cf338b 75 PRINTS PR01651 Protein-export SecG membrane protein signature 2 22 2.8E-5 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TSC_c02830 0b06fd7dab820ea0ec0b5b0130cf338b 75 PRINTS PR01651 Protein-export SecG membrane protein signature 38 54 2.8E-5 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TSC_c02830 0b06fd7dab820ea0ec0b5b0130cf338b 75 PRINTS PR01651 Protein-export SecG membrane protein signature 54 75 2.8E-5 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TSC_c02830 0b06fd7dab820ea0ec0b5b0130cf338b 75 Pfam PF03840 Preprotein translocase SecG subunit 8 72 1.8E-13 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TSC_c02830 0b06fd7dab820ea0ec0b5b0130cf338b 75 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 5 73 1.2E-15 T 12-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 TSC_c08510 9b749316100815a4a6797be9b49674a5 157 SUPERFAMILY SSF54523 7 83 1.02E-9 T 12-10-2018 TSC_c08510 9b749316100815a4a6797be9b49674a5 157 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 3 26 1.1E-4 T 12-10-2018 IPR012902 Prokaryotic N-terminal methylation site TSC_c07420 0e353291edd4dc171583cdfe3780fa53 82 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 7 82 3.2E-35 T 12-10-2018 IPR019886 Sodium symporter small subunit, predicted TSC_c07420 0e353291edd4dc171583cdfe3780fa53 82 Pfam PF13937 Domain of unknown function (DUF4212) 5 81 2.1E-35 T 12-10-2018 IPR019886 Sodium symporter small subunit, predicted TSC_c13870 2b162d7a5f6e92d825286a0073fdee38 171 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 12 169 17.723 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 TSC_c13870 2b162d7a5f6e92d825286a0073fdee38 171 Pfam PF01782 RimM N-terminal domain 14 88 5.0E-6 T 12-10-2018 IPR002676 RimM, N-terminal GO:0006364 TSC_c13870 2b162d7a5f6e92d825286a0073fdee38 171 Pfam PF05239 PRC-barrel domain 96 168 5.4E-5 T 12-10-2018 IPR027275 PRC-barrel domain TSC_c13870 2b162d7a5f6e92d825286a0073fdee38 171 SUPERFAMILY SSF50447 12 92 7.42E-7 T 12-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily TSC_c13870 2b162d7a5f6e92d825286a0073fdee38 171 Gene3D G3DSA:2.30.30.240 94 164 5.9E-28 T 12-10-2018 TSC_c13870 2b162d7a5f6e92d825286a0073fdee38 171 Gene3D G3DSA:2.40.30.60 10 93 1.3E-36 T 12-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 TSC_c13870 2b162d7a5f6e92d825286a0073fdee38 171 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 13 155 2.2E-26 T 12-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 TSC_c13870 2b162d7a5f6e92d825286a0073fdee38 171 SUPERFAMILY SSF50346 98 169 4.32E-10 T 12-10-2018 IPR011033 PRC-barrel-like superfamily TSC_c11640 8a3ccd752bfbbfc6a06586357a495f54 243 Gene3D G3DSA:2.60.120.10 19 125 3.9E-12 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TSC_c11640 8a3ccd752bfbbfc6a06586357a495f54 243 Pfam PF07883 Cupin domain 47 113 3.8E-10 T 12-10-2018 IPR013096 Cupin 2, conserved barrel TSC_c11640 8a3ccd752bfbbfc6a06586357a495f54 243 Gene3D G3DSA:2.60.120.10 138 241 8.0E-10 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TSC_c11640 8a3ccd752bfbbfc6a06586357a495f54 243 SUPERFAMILY SSF51182 46 214 2.28E-14 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TSC_c13890 e3c48c61c37498ba54e26db7c00f7b59 84 SUPERFAMILY SSF54565 1 81 1.57E-33 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c13890 e3c48c61c37498ba54e26db7c00f7b59 84 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 80 4.1E-35 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c13890 e3c48c61c37498ba54e26db7c00f7b59 84 Pfam PF00886 Ribosomal protein S16 8 67 2.9E-26 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c13890 e3c48c61c37498ba54e26db7c00f7b59 84 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 77 25.324 T 12-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c13890 e3c48c61c37498ba54e26db7c00f7b59 84 Gene3D G3DSA:3.30.1320.10 1 84 1.6E-37 T 12-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c08380 380fc0193591172a29bfa6366b4b915a 321 SUPERFAMILY SSF51905 1 319 9.71E-42 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c08380 380fc0193591172a29bfa6366b4b915a 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 178 4.6E-14 T 12-10-2018 TSC_c08380 380fc0193591172a29bfa6366b4b915a 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 291 4.6E-14 T 12-10-2018 TSC_c08380 380fc0193591172a29bfa6366b4b915a 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 259 4.6E-14 T 12-10-2018 TSC_c08380 380fc0193591172a29bfa6366b4b915a 321 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 4.6E-14 T 12-10-2018 TSC_c08380 380fc0193591172a29bfa6366b4b915a 321 Gene3D G3DSA:3.50.50.60 3 291 1.4E-51 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c08380 380fc0193591172a29bfa6366b4b915a 321 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 5 288 4.9E-65 T 12-10-2018 TSC_c08380 380fc0193591172a29bfa6366b4b915a 321 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 3 317 8.3E-113 T 12-10-2018 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA TSC_c08380 380fc0193591172a29bfa6366b4b915a 321 Gene3D G3DSA:3.50.50.60 133 250 1.4E-51 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c08380 380fc0193591172a29bfa6366b4b915a 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 121 129 4.7E-18 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c08380 380fc0193591172a29bfa6366b4b915a 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 156 180 4.7E-18 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c08380 380fc0193591172a29bfa6366b4b915a 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 4.7E-18 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c08380 380fc0193591172a29bfa6366b4b915a 321 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 279 297 4.7E-18 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c23220 7ba91a04308f1fdadc9c62930bab32ea 336 SUPERFAMILY SSF161098 94 319 9.65E-19 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c23220 7ba91a04308f1fdadc9c62930bab32ea 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 335 2.5E-46 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c15830 a96d18efb29679b800fcd702c2c1e6d9 453 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 360 433 6.6E-8 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TSC_c15830 a96d18efb29679b800fcd702c2c1e6d9 453 Gene3D G3DSA:1.10.8.60 359 452 1.2E-8 T 12-10-2018 TSC_c15830 a96d18efb29679b800fcd702c2c1e6d9 453 SUPERFAMILY SSF52540 156 426 1.49E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c15830 a96d18efb29679b800fcd702c2c1e6d9 453 Gene3D G3DSA:3.40.50.300 152 357 3.3E-59 T 12-10-2018 TSC_c15830 a96d18efb29679b800fcd702c2c1e6d9 453 SMART SM01086 359 450 0.0065 T 12-10-2018 IPR019489 Clp ATPase, C-terminal TSC_c15830 a96d18efb29679b800fcd702c2c1e6d9 453 SMART SM00382 195 360 7.9E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c15830 a96d18efb29679b800fcd702c2c1e6d9 453 Pfam PF07724 AAA domain (Cdc48 subfamily) 197 352 7.1E-25 T 12-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 TSC_c15830 a96d18efb29679b800fcd702c2c1e6d9 453 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 241 259 3.0E-24 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TSC_c15830 a96d18efb29679b800fcd702c2c1e6d9 453 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 270 288 3.0E-24 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TSC_c15830 a96d18efb29679b800fcd702c2c1e6d9 453 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 199 217 3.0E-24 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TSC_c15830 a96d18efb29679b800fcd702c2c1e6d9 453 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 304 318 3.0E-24 T 12-10-2018 IPR001270 ClpA/B family GO:0005524 TSC_c01530 dad5e148834aa1effe341f18056bde46 469 SUPERFAMILY SSF55931 4 288 1.18E-110 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TSC_c01530 dad5e148834aa1effe341f18056bde46 469 Gene3D G3DSA:1.10.150.380 289 393 4.0E-27 T 12-10-2018 TSC_c01530 dad5e148834aa1effe341f18056bde46 469 Gene3D G3DSA:1.10.10.410 406 467 5.8E-19 T 12-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal TSC_c01530 dad5e148834aa1effe341f18056bde46 469 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 1 467 37.655 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 TSC_c01530 dad5e148834aa1effe341f18056bde46 469 Pfam PF02637 GatB domain 321 466 2.3E-41 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TSC_c01530 dad5e148834aa1effe341f18056bde46 469 SUPERFAMILY SSF89095 289 393 2.09E-21 T 12-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 TSC_c01530 dad5e148834aa1effe341f18056bde46 469 Pfam PF02934 GatB/GatE catalytic domain 5 281 3.5E-108 T 12-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 TSC_c01530 dad5e148834aa1effe341f18056bde46 469 SMART SM00845 319 466 3.2E-54 T 12-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 TSC_c01530 dad5e148834aa1effe341f18056bde46 469 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 2 466 2.5E-158 T 12-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 TSC_c01530 dad5e148834aa1effe341f18056bde46 469 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 137 151 - T 12-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 TSC_c04790 fb185523125b4f7c886edc155d090df9 403 Gene3D G3DSA:1.20.1250.20 9 392 1.6E-36 T 12-10-2018 TSC_c04790 fb185523125b4f7c886edc155d090df9 403 SUPERFAMILY SSF103473 12 398 4.05E-40 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c04790 fb185523125b4f7c886edc155d090df9 403 Pfam PF05977 Transmembrane secretion effector 10 329 2.1E-21 T 12-10-2018 IPR010290 Transmembrane secretion effector TSC_c12380 b0a57b29c8b18d6cd9fc436b53ee55fa 80 Pfam PF00872 Transposase, Mutator family 2 74 1.6E-15 T 12-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 TSC_c14610 4e8572db4f55c843a1ee31023650d7e0 284 Pfam PF13247 4Fe-4S dicluster domain 217 250 3.5E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c14610 4e8572db4f55c843a1ee31023650d7e0 284 Pfam PF13247 4Fe-4S dicluster domain 120 179 2.6E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c14610 4e8572db4f55c843a1ee31023650d7e0 284 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 160 171 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c14610 4e8572db4f55c843a1ee31023650d7e0 284 SUPERFAMILY SSF54862 72 283 1.15E-62 T 12-10-2018 TSC_c14610 4e8572db4f55c843a1ee31023650d7e0 284 Gene3D G3DSA:3.30.70.20 58 106 2.8E-10 T 12-10-2018 TSC_c22330 40a53a34fdb4ed735ba7b54939943cac 110 SMART SM00739 6 33 4.4E-6 T 12-10-2018 IPR005824 KOW TSC_c22330 40a53a34fdb4ed735ba7b54939943cac 110 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 5 101 18.193 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22330 40a53a34fdb4ed735ba7b54939943cac 110 ProSitePatterns PS01108 Ribosomal protein L24 signature. 10 27 - T 12-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22330 40a53a34fdb4ed735ba7b54939943cac 110 SUPERFAMILY SSF50104 4 103 1.03E-34 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily TSC_c22330 40a53a34fdb4ed735ba7b54939943cac 110 Gene3D G3DSA:2.30.30.30 1 104 2.2E-38 T 12-10-2018 IPR014722 Ribosomal protein L2, domain 2 TSC_c22330 40a53a34fdb4ed735ba7b54939943cac 110 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 42 103 1.7E-24 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22330 40a53a34fdb4ed735ba7b54939943cac 110 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 5 104 8.0E-36 T 12-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22330 40a53a34fdb4ed735ba7b54939943cac 110 Pfam PF00467 KOW motif 9 40 2.0E-7 T 12-10-2018 IPR005824 KOW TSC_c12710 4b4d9bd56156c86073a862e55939a2fd 400 SUPERFAMILY SSF53901 276 398 3.4E-47 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c12710 4b4d9bd56156c86073a862e55939a2fd 400 ProSitePatterns PS00737 Thiolases signature 2. 346 362 - T 12-10-2018 IPR020613 Thiolase, conserved site GO:0016747 TSC_c12710 4b4d9bd56156c86073a862e55939a2fd 400 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 12-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 TSC_c12710 4b4d9bd56156c86073a862e55939a2fd 400 Gene3D G3DSA:3.40.47.10 6 281 4.8E-173 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c12710 4b4d9bd56156c86073a862e55939a2fd 400 SUPERFAMILY SSF53901 3 275 1.29E-86 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c12710 4b4d9bd56156c86073a862e55939a2fd 400 ProSitePatterns PS00099 Thiolases active site. 381 394 - T 12-10-2018 IPR020610 Thiolase, active site GO:0016747 TSC_c12710 4b4d9bd56156c86073a862e55939a2fd 400 Pfam PF00108 Thiolase, N-terminal domain 6 267 1.4E-80 T 12-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 TSC_c12710 4b4d9bd56156c86073a862e55939a2fd 400 Gene3D G3DSA:3.40.47.10 141 397 4.8E-173 T 12-10-2018 IPR016039 Thiolase-like GO:0003824 TSC_c12710 4b4d9bd56156c86073a862e55939a2fd 400 PIRSF PIRSF000429 1 400 1.2E-143 T 12-10-2018 IPR002155 Thiolase GO:0016747 TSC_c12710 4b4d9bd56156c86073a862e55939a2fd 400 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 398 2.2E-146 T 12-10-2018 IPR002155 Thiolase GO:0016747 TSC_c12710 4b4d9bd56156c86073a862e55939a2fd 400 Pfam PF02803 Thiolase, C-terminal domain 275 398 1.2E-49 T 12-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 TSC_c10510 3391088fa1ea29c829bcbc1df544dee8 253 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 217 235 1.1E-5 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSC_c10510 3391088fa1ea29c829bcbc1df544dee8 253 SUPERFAMILY SSF52540 3 235 2.98E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c10510 3391088fa1ea29c829bcbc1df544dee8 253 Pfam PF00005 ABC transporter 20 164 5.4E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c10510 3391088fa1ea29c829bcbc1df544dee8 253 SMART SM00382 28 213 2.1E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c10510 3391088fa1ea29c829bcbc1df544dee8 253 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c10510 3391088fa1ea29c829bcbc1df544dee8 253 Gene3D G3DSA:3.40.50.300 2 237 9.1E-60 T 12-10-2018 TSC_c00580 2155f4afd4c8d6901038dfbe01681d4d 415 SMART SM00710 200 221 7100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TSC_c00580 2155f4afd4c8d6901038dfbe01681d4d 415 SMART SM00710 155 176 170.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TSC_c00580 2155f4afd4c8d6901038dfbe01681d4d 415 SMART SM00710 270 291 8100.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TSC_c00580 2155f4afd4c8d6901038dfbe01681d4d 415 SMART SM00710 131 154 3000.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TSC_c00580 2155f4afd4c8d6901038dfbe01681d4d 415 SMART SM00710 177 199 1900.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TSC_c00580 2155f4afd4c8d6901038dfbe01681d4d 415 SMART SM00710 78 108 2200.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TSC_c00580 2155f4afd4c8d6901038dfbe01681d4d 415 SMART SM00710 222 247 1700.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TSC_c00580 2155f4afd4c8d6901038dfbe01681d4d 415 SMART SM00710 109 130 3500.0 T 12-10-2018 IPR006626 Parallel beta-helix repeat TSC_c00580 2155f4afd4c8d6901038dfbe01681d4d 415 Pfam PF05048 Periplasmic copper-binding protein (NosD) 148 316 2.9E-20 T 12-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 TSC_c00580 2155f4afd4c8d6901038dfbe01681d4d 415 SUPERFAMILY SSF51126 57 310 5.09E-25 T 12-10-2018 IPR011050 Pectin lyase fold/virulence factor TSC_c00580 2155f4afd4c8d6901038dfbe01681d4d 415 Gene3D G3DSA:2.160.20.10 130 334 8.1E-19 T 12-10-2018 IPR012334 Pectin lyase fold TSC_c02820 7e72d7088fecfd70c17646d2be6cd5c9 312 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 41 54 - T 12-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 TSC_c02820 7e72d7088fecfd70c17646d2be6cd5c9 312 Gene3D G3DSA:3.40.50.1100 49 142 3.8E-116 T 12-10-2018 TSC_c02820 7e72d7088fecfd70c17646d2be6cd5c9 312 Gene3D G3DSA:3.40.50.1100 15 305 3.8E-116 T 12-10-2018 TSC_c02820 7e72d7088fecfd70c17646d2be6cd5c9 312 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 14 296 6.2E-76 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSC_c02820 7e72d7088fecfd70c17646d2be6cd5c9 312 SUPERFAMILY SSF53686 3 294 7.73E-86 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSC_c24240 528b7638c11207d20106b3dbd5d7a756 523 SMART SM00065 26 172 2.1E-16 T 12-10-2018 IPR003018 GAF domain GO:0005515 TSC_c24240 528b7638c11207d20106b3dbd5d7a756 523 SMART SM00065 193 341 1.1E-5 T 12-10-2018 IPR003018 GAF domain GO:0005515 TSC_c24240 528b7638c11207d20106b3dbd5d7a756 523 Pfam PF13185 GAF domain 192 332 7.4E-14 T 12-10-2018 IPR003018 GAF domain GO:0005515 TSC_c24240 528b7638c11207d20106b3dbd5d7a756 523 Pfam PF13185 GAF domain 27 162 1.2E-11 T 12-10-2018 IPR003018 GAF domain GO:0005515 TSC_c24240 528b7638c11207d20106b3dbd5d7a756 523 SMART SM00471 358 492 6.2E-11 T 12-10-2018 IPR003607 HD/PDEase domain TSC_c24240 528b7638c11207d20106b3dbd5d7a756 523 Gene3D G3DSA:1.10.3210.10 343 523 1.3E-66 T 12-10-2018 TSC_c24240 528b7638c11207d20106b3dbd5d7a756 523 SUPERFAMILY SSF55781 159 333 1.18E-18 T 12-10-2018 TSC_c24240 528b7638c11207d20106b3dbd5d7a756 523 SUPERFAMILY SSF109604 336 522 8.28E-39 T 12-10-2018 TSC_c24240 528b7638c11207d20106b3dbd5d7a756 523 Pfam PF13487 HD domain 413 473 2.6E-21 T 12-10-2018 TSC_c24240 528b7638c11207d20106b3dbd5d7a756 523 SUPERFAMILY SSF55781 8 174 9.81E-23 T 12-10-2018 TSC_c24240 528b7638c11207d20106b3dbd5d7a756 523 Gene3D G3DSA:3.30.450.40 172 342 7.5E-21 T 12-10-2018 IPR029016 GAF-like domain superfamily TSC_c24240 528b7638c11207d20106b3dbd5d7a756 523 Gene3D G3DSA:3.30.450.40 4 171 2.4E-24 T 12-10-2018 IPR029016 GAF-like domain superfamily TSC_c00330 ac6dd0684a6f4f36a536c93d2d29d787 304 SUPERFAMILY SSF53686 3 302 1.57E-96 T 12-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme TSC_c00330 ac6dd0684a6f4f36a536c93d2d29d787 304 Gene3D G3DSA:3.40.50.1100 34 155 3.0E-120 T 12-10-2018 TSC_c00330 ac6dd0684a6f4f36a536c93d2d29d787 304 TIGRFAM TIGR01139 cysK: cysteine synthase A 4 301 1.9E-124 T 12-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 TSC_c00330 ac6dd0684a6f4f36a536c93d2d29d787 304 TIGRFAM TIGR01136 cysKM: cysteine synthase 4 301 1.9E-123 T 12-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 TSC_c00330 ac6dd0684a6f4f36a536c93d2d29d787 304 Gene3D G3DSA:3.40.50.1100 7 296 3.0E-120 T 12-10-2018 TSC_c00330 ac6dd0684a6f4f36a536c93d2d29d787 304 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 4 289 1.5E-66 T 12-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme TSC_c00330 ac6dd0684a6f4f36a536c93d2d29d787 304 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 29 47 - T 12-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 TSC_c07720 3c6342981a4864b8012b76c5e650b977 142 SUPERFAMILY SSF54523 1 83 9.42E-5 T 12-10-2018 TSC_c07720 3c6342981a4864b8012b76c5e650b977 142 Pfam PF12019 Type II transport protein GspH 26 137 3.1E-13 T 12-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 TSC_c07630 0505202330869f439abc55daf4199c4a 201 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 2 197 35.388 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 TSC_c07630 0505202330869f439abc55daf4199c4a 201 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 3 183 4.5E-40 T 12-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 TSC_c07630 0505202330869f439abc55daf4199c4a 201 Pfam PF00694 Aconitase C-terminal domain 3 120 3.1E-20 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 TSC_c07630 0505202330869f439abc55daf4199c4a 201 SUPERFAMILY SSF52016 3 188 6.47E-47 T 12-10-2018 TSC_c07630 0505202330869f439abc55daf4199c4a 201 Gene3D G3DSA:3.20.19.10 1 178 3.0E-56 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 TSC_c12700 a97534a7086d6f1166bc3f1bc6203ac2 663 PIRSF PIRSF006402 628 661 67.0 T 12-10-2018 IPR024705 Spermatogenesis-associated protein 20 TSC_c12700 a97534a7086d6f1166bc3f1bc6203ac2 663 PIRSF PIRSF006402 1 607 4.1E-194 T 12-10-2018 IPR024705 Spermatogenesis-associated protein 20 TSC_c12700 a97534a7086d6f1166bc3f1bc6203ac2 663 Gene3D G3DSA:3.40.30.10 1 168 4.1E-67 T 12-10-2018 TSC_c12700 a97534a7086d6f1166bc3f1bc6203ac2 663 SUPERFAMILY SSF52833 2 127 6.49E-31 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TSC_c12700 a97534a7086d6f1166bc3f1bc6203ac2 663 SUPERFAMILY SSF48208 177 507 9.23E-56 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TSC_c12700 a97534a7086d6f1166bc3f1bc6203ac2 663 Pfam PF03190 Protein of unknown function, DUF255 3 163 6.9E-73 T 12-10-2018 IPR004879 Domain of unknown function DUF255 TSC_c11250 ca9b55bac50384cc0887e1988f6512ab 174 PRINTS PR00162 Rieske 2Fe-2S subunit signature 159 171 1.7E-6 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TSC_c11250 ca9b55bac50384cc0887e1988f6512ab 174 PRINTS PR00162 Rieske 2Fe-2S subunit signature 124 135 1.7E-6 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TSC_c11250 ca9b55bac50384cc0887e1988f6512ab 174 PRINTS PR00162 Rieske 2Fe-2S subunit signature 146 158 1.7E-6 T 12-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 TSC_c11250 ca9b55bac50384cc0887e1988f6512ab 174 Pfam PF00355 Rieske [2Fe-2S] domain 119 171 8.7E-11 T 12-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 TSC_c11250 ca9b55bac50384cc0887e1988f6512ab 174 Gene3D G3DSA:2.102.10.10 44 174 1.6E-36 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSC_c11250 ca9b55bac50384cc0887e1988f6512ab 174 SUPERFAMILY SSF50022 65 172 9.95E-22 T 12-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 TSC_c16690 11a5c87ad2af9667256b69c3763d94db 426 Gene3D G3DSA:3.90.350.10 97 345 5.8E-26 T 12-10-2018 IPR014736 Transposase, Tn5-like, core TSC_c16690 11a5c87ad2af9667256b69c3763d94db 426 Pfam PF01609 Transposase DDE domain 199 354 1.6E-14 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TSC_c16690 11a5c87ad2af9667256b69c3763d94db 426 SUPERFAMILY SSF53098 42 416 2.12E-46 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c04220 11a5c87ad2af9667256b69c3763d94db 426 Gene3D G3DSA:3.90.350.10 97 345 5.8E-26 T 12-10-2018 IPR014736 Transposase, Tn5-like, core TSC_c04220 11a5c87ad2af9667256b69c3763d94db 426 Pfam PF01609 Transposase DDE domain 199 354 1.6E-14 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TSC_c04220 11a5c87ad2af9667256b69c3763d94db 426 SUPERFAMILY SSF53098 42 416 2.12E-46 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c04670 11a5c87ad2af9667256b69c3763d94db 426 Gene3D G3DSA:3.90.350.10 97 345 5.8E-26 T 12-10-2018 IPR014736 Transposase, Tn5-like, core TSC_c04670 11a5c87ad2af9667256b69c3763d94db 426 Pfam PF01609 Transposase DDE domain 199 354 1.6E-14 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TSC_c04670 11a5c87ad2af9667256b69c3763d94db 426 SUPERFAMILY SSF53098 42 416 2.12E-46 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c02550 cf00f18d470269f01aff0ab77cc99f65 262 Gene3D G3DSA:3.10.520.20 100 258 9.7E-33 T 12-10-2018 TSC_c02550 cf00f18d470269f01aff0ab77cc99f65 262 Pfam PF02424 ApbE family 109 231 5.0E-27 T 12-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 TSC_c02550 cf00f18d470269f01aff0ab77cc99f65 262 Pfam PF02424 ApbE family 32 89 5.2E-7 T 12-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 TSC_c02550 cf00f18d470269f01aff0ab77cc99f65 262 Gene3D G3DSA:3.10.520.20 8 99 3.4E-8 T 12-10-2018 TSC_c02550 cf00f18d470269f01aff0ab77cc99f65 262 SUPERFAMILY SSF143631 11 250 2.75E-45 T 12-10-2018 IPR003374 ApbE-like superfamily TSC_c20140 818deda31bff2c261610a0ce33c0ba3e 80 SUPERFAMILY SSF47598 4 44 1.78E-8 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TSC_c20140 818deda31bff2c261610a0ce33c0ba3e 80 Pfam PF05534 HicB family 4 36 3.8E-8 T 12-10-2018 IPR008651 Uncharacterised protein family HicB TSC_c15530 168386bab5c96a29563c894af9df92b7 684 Gene3D G3DSA:3.30.70.100 7 72 2.5E-12 T 12-10-2018 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 ProSitePatterns PS01047 Heavy-metal-associated domain. 11 40 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 SUPERFAMILY SSF55008 8 71 2.09E-13 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 SUPERFAMILY SSF56784 386 677 1.89E-38 T 12-10-2018 IPR036412 HAD-like superfamily TSC_c15530 168386bab5c96a29563c894af9df92b7 684 PRINTS PR00941 Cadmium-transporting ATPase signature 20 41 6.6E-10 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 PRINTS PR00941 Cadmium-transporting ATPase signature 253 269 6.6E-10 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 PRINTS PR00941 Cadmium-transporting ATPase signature 172 192 6.6E-10 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 PRINTS PR00941 Cadmium-transporting ATPase signature 9 18 6.6E-10 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 237 251 1.2E-22 T 12-10-2018 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 579 598 1.2E-22 T 12-10-2018 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 503 514 1.2E-22 T 12-10-2018 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 387 401 1.2E-22 T 12-10-2018 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 602 614 1.2E-22 T 12-10-2018 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 525 535 1.2E-22 T 12-10-2018 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 Pfam PF00403 Heavy-metal-associated domain 8 67 4.0E-10 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 Pfam PF00702 haloacid dehalogenase-like hydrolase 384 592 7.8E-32 T 12-10-2018 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 137 679 3.3E-149 T 12-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 SUPERFAMILY SSF81653 190 283 1.44E-22 T 12-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 389 395 - T 12-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 160 415 1.9E-37 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 478 654 5.2E-28 T 12-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 Pfam PF00122 E1-E2 ATPase 187 366 2.6E-48 T 12-10-2018 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 SUPERFAMILY SSF81665 140 381 1.96E-15 T 12-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 Gene3D G3DSA:3.40.1110.10 398 510 2.4E-65 T 12-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 TSC_c15530 168386bab5c96a29563c894af9df92b7 684 Gene3D G3DSA:3.40.50.1000 368 629 2.4E-65 T 12-10-2018 IPR023214 HAD superfamily TSC_c15530 168386bab5c96a29563c894af9df92b7 684 Gene3D G3DSA:2.70.150.20 181 291 4.0E-29 T 12-10-2018 TSC_c04270 674bda183404ecf22fd6983e720fc6ed 282 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 99 113 2.5E-8 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TSC_c04270 674bda183404ecf22fd6983e720fc6ed 282 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 55 66 2.5E-8 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TSC_c04270 674bda183404ecf22fd6983e720fc6ed 282 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 28 36 2.5E-8 T 12-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 TSC_c04270 674bda183404ecf22fd6983e720fc6ed 282 SUPERFAMILY SSF53474 4 274 9.62E-46 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c04270 674bda183404ecf22fd6983e720fc6ed 282 Gene3D G3DSA:3.40.50.1820 1 275 4.6E-87 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c04270 674bda183404ecf22fd6983e720fc6ed 282 Pfam PF12697 Alpha/beta hydrolase family 28 265 2.8E-19 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSC_c24570 bb6510016ff197260e06aca973078142 293 SUPERFAMILY SSF52768 4 273 6.23E-78 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily TSC_c24570 bb6510016ff197260e06aca973078142 293 Pfam PF00850 Histone deacetylase domain 22 273 9.2E-49 T 12-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSC_c24570 bb6510016ff197260e06aca973078142 293 PRINTS PR01270 Histone deacetylase superfamily signature 110 133 2.6E-13 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSC_c24570 bb6510016ff197260e06aca973078142 293 PRINTS PR01270 Histone deacetylase superfamily signature 217 227 2.6E-13 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSC_c24570 bb6510016ff197260e06aca973078142 293 PRINTS PR01270 Histone deacetylase superfamily signature 144 159 2.6E-13 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSC_c24570 bb6510016ff197260e06aca973078142 293 Gene3D G3DSA:3.40.800.20 2 288 7.7E-68 T 12-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSC_c24530 78bd16483f79cb6d4f0443f5e7c8da43 61 SUPERFAMILY SSF143120 1 40 7.32E-5 T 12-10-2018 IPR036165 YefM-like superfamily TSC_c24530 78bd16483f79cb6d4f0443f5e7c8da43 61 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 2 36 6.5E-6 T 12-10-2018 TSC_c24530 78bd16483f79cb6d4f0443f5e7c8da43 61 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 45 3.1E-7 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TSC_c09540 68ab68e0302e54d3360cd45c50411ef5 259 Pfam PF00005 ABC transporter 19 168 4.3E-22 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c09540 68ab68e0302e54d3360cd45c50411ef5 259 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c09540 68ab68e0302e54d3360cd45c50411ef5 259 SMART SM00382 28 218 2.7E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c09540 68ab68e0302e54d3360cd45c50411ef5 259 SUPERFAMILY SSF52540 2 240 1.88E-49 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c09540 68ab68e0302e54d3360cd45c50411ef5 259 Gene3D G3DSA:3.40.50.300 1 256 1.7E-49 T 12-10-2018 TSC_c03550 7ddb5c194113eff59c65393e4bd9c581 397 Pfam PF00202 Aminotransferase class-III 31 395 6.7E-112 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c03550 7ddb5c194113eff59c65393e4bd9c581 397 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 25 396 1.7E-135 T 12-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 TSC_c03550 7ddb5c194113eff59c65393e4bd9c581 397 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 224 261 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c03550 7ddb5c194113eff59c65393e4bd9c581 397 Gene3D G3DSA:3.40.640.10 65 306 4.5E-157 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c03550 7ddb5c194113eff59c65393e4bd9c581 397 SUPERFAMILY SSF53383 25 396 2.18E-126 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c03550 7ddb5c194113eff59c65393e4bd9c581 397 PIRSF PIRSF000521 171 397 9.2E-37 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c03550 7ddb5c194113eff59c65393e4bd9c581 397 PIRSF PIRSF000521 16 150 2.5E-8 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c03550 7ddb5c194113eff59c65393e4bd9c581 397 PIRSF PIRSF000521 132 162 23.0 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c03550 7ddb5c194113eff59c65393e4bd9c581 397 Hamap MF_02084 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase [lysJ]. 23 397 49.132 T 12-10-2018 IPR037537 [LysW]-aminoadipate semialdehyde/glutamate semialdehyde transaminase GO:0008483 TSC_c03550 7ddb5c194113eff59c65393e4bd9c581 397 Gene3D G3DSA:3.90.1150.10 32 390 4.5E-157 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c03880 74ff601f89f95d177d3240107ed5cf16 66 ProSitePatterns PS01047 Heavy-metal-associated domain. 6 35 - T 12-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 TSC_c03880 74ff601f89f95d177d3240107ed5cf16 66 Pfam PF00403 Heavy-metal-associated domain 4 60 1.7E-17 T 12-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 TSC_c03880 74ff601f89f95d177d3240107ed5cf16 66 Gene3D G3DSA:3.30.70.100 1 65 2.1E-27 T 12-10-2018 TSC_c03880 74ff601f89f95d177d3240107ed5cf16 66 SUPERFAMILY SSF55008 2 64 1.31E-20 T 12-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 TSC_c01830 ccc8d9b8f0af6744dc9f4c4ac92898dd 372 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 329 348 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSC_c01830 ccc8d9b8f0af6744dc9f4c4ac92898dd 372 SUPERFAMILY SSF56645 2 235 2.09E-81 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSC_c01830 ccc8d9b8f0af6744dc9f4c4ac92898dd 372 Gene3D G3DSA:1.10.540.10 1 118 1.7E-37 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSC_c01830 ccc8d9b8f0af6744dc9f4c4ac92898dd 372 Gene3D G3DSA:2.40.110.10 119 226 1.5E-39 T 12-10-2018 TSC_c01830 ccc8d9b8f0af6744dc9f4c4ac92898dd 372 PIRSF PIRSF016578 1 372 2.3E-25 T 12-10-2018 TSC_c01830 ccc8d9b8f0af6744dc9f4c4ac92898dd 372 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 120 210 1.0E-26 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSC_c01830 ccc8d9b8f0af6744dc9f4c4ac92898dd 372 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 222 370 1.0E-51 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSC_c01830 ccc8d9b8f0af6744dc9f4c4ac92898dd 372 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 116 4.6E-33 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSC_c01830 ccc8d9b8f0af6744dc9f4c4ac92898dd 372 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 122 134 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSC_c01830 ccc8d9b8f0af6744dc9f4c4ac92898dd 372 SUPERFAMILY SSF47203 220 371 8.05E-57 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSC_c01830 ccc8d9b8f0af6744dc9f4c4ac92898dd 372 Gene3D G3DSA:1.20.140.10 227 371 5.9E-55 T 12-10-2018 TSC_c01660 a2f55adb974aad85cc7b3577edff7851 183 Gene3D G3DSA:1.10.340.30 26 134 4.4E-55 T 12-10-2018 TSC_c01660 a2f55adb974aad85cc7b3577edff7851 183 SUPERFAMILY SSF48150 25 181 2.44E-39 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TSC_c01660 a2f55adb974aad85cc7b3577edff7851 183 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 155 9.8E-14 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSC_c01660 a2f55adb974aad85cc7b3577edff7851 183 Gene3D G3DSA:1.10.1670.40 4 180 4.4E-55 T 12-10-2018 TSC_c01660 a2f55adb974aad85cc7b3577edff7851 183 SMART SM00478 38 183 1.6E-14 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSC_c04050 cd7a8e123cec5d1f82f1d4aaac166cce 278 Gene3D G3DSA:1.10.3720.10 45 277 4.1E-59 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c04050 cd7a8e123cec5d1f82f1d4aaac166cce 278 SUPERFAMILY SSF161098 47 265 1.96E-48 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c04050 cd7a8e123cec5d1f82f1d4aaac166cce 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 66 267 5.1E-8 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c16800 cd65cc097d475621a8faf2401ac2cfc2 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 260 7.3E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c16800 cd65cc097d475621a8faf2401ac2cfc2 271 Gene3D G3DSA:1.10.3720.10 3 262 3.9E-63 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c16800 cd65cc097d475621a8faf2401ac2cfc2 271 SUPERFAMILY SSF161098 2 271 1.7E-68 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c21220 da3d6b318d2235d6c68d0abf884066f0 736 SUPERFAMILY SSF52540 6 447 1.25E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c15060 cd3993df8d01ba9384a8cd0ce53bb95c 490 Pfam PF02386 Cation transport protein 76 482 3.6E-61 T 12-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 TSC_c15060 cd3993df8d01ba9384a8cd0ce53bb95c 490 PIRSF PIRSF006247 8 488 9.4E-167 T 12-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 TSC_c15660 4a727853e78655d5411b0d00e37b4a87 589 Pfam PF03235 Protein of unknown function DUF262 15 226 2.1E-30 T 12-10-2018 IPR004919 Domain of unknown function DUF262 TSC_c06980 c12cb7dffd1a48b3acdcf111a1fa445c 316 SMART SM00387 226 316 0.0062 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c06980 c12cb7dffd1a48b3acdcf111a1fa445c 316 Pfam PF07730 Histidine kinase 132 189 8.9E-12 T 12-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 TSC_c06980 c12cb7dffd1a48b3acdcf111a1fa445c 316 Gene3D G3DSA:3.30.565.10 193 316 1.5E-32 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c06980 c12cb7dffd1a48b3acdcf111a1fa445c 316 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 227 316 1.2E-8 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c06980 c12cb7dffd1a48b3acdcf111a1fa445c 316 SUPERFAMILY SSF55874 197 316 5.63E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c24440 852e9d41ad402c691fe6bc9fc40fec0e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 7.3E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c24440 852e9d41ad402c691fe6bc9fc40fec0e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 7.3E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c24440 852e9d41ad402c691fe6bc9fc40fec0e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 7.3E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c24440 852e9d41ad402c691fe6bc9fc40fec0e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 7.3E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c24440 852e9d41ad402c691fe6bc9fc40fec0e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 7.3E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c24440 852e9d41ad402c691fe6bc9fc40fec0e 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 7.3E-13 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c24440 852e9d41ad402c691fe6bc9fc40fec0e 259 SUPERFAMILY SSF51735 8 256 2.34E-70 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c24440 852e9d41ad402c691fe6bc9fc40fec0e 259 PIRSF PIRSF000094 3 259 3.2E-102 T 12-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TSC_c24440 852e9d41ad402c691fe6bc9fc40fec0e 259 Gene3D G3DSA:1.10.8.400 203 258 1.0E-20 T 12-10-2018 TSC_c24440 852e9d41ad402c691fe6bc9fc40fec0e 259 Gene3D G3DSA:3.40.50.720 9 200 4.0E-41 T 12-10-2018 TSC_c24440 852e9d41ad402c691fe6bc9fc40fec0e 259 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 252 1.0E-85 T 12-10-2018 TSC_c10070 a8882537a6c70a1532819e828b0e688d 245 Pfam PF02634 FdhD/NarQ family 18 232 3.4E-43 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TSC_c10070 a8882537a6c70a1532819e828b0e688d 245 SUPERFAMILY SSF53927 2 232 6.92E-49 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TSC_c10070 a8882537a6c70a1532819e828b0e688d 245 PIRSF PIRSF015626 2 236 5.3E-44 T 12-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 TSC_c10070 a8882537a6c70a1532819e828b0e688d 245 Gene3D G3DSA:3.40.140.10 96 236 1.7E-34 T 12-10-2018 TSC_c08910 053d03eb398b3813fb34a7b5781a9b06 284 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 124 154 - T 12-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 TSC_c08910 053d03eb398b3813fb34a7b5781a9b06 284 Pfam PF00701 Dihydrodipicolinate synthetase family 2 261 1.6E-44 T 12-10-2018 IPR002220 DapA-like GO:0016829 TSC_c08910 053d03eb398b3813fb34a7b5781a9b06 284 SUPERFAMILY SSF51569 2 265 4.19E-64 T 12-10-2018 TSC_c08910 053d03eb398b3813fb34a7b5781a9b06 284 PRINTS PR00146 Dihydrodipicolinate synthase signature 119 136 1.7E-8 T 12-10-2018 IPR002220 DapA-like GO:0016829 TSC_c08910 053d03eb398b3813fb34a7b5781a9b06 284 PRINTS PR00146 Dihydrodipicolinate synthase signature 96 112 1.7E-8 T 12-10-2018 IPR002220 DapA-like GO:0016829 TSC_c08910 053d03eb398b3813fb34a7b5781a9b06 284 PRINTS PR00146 Dihydrodipicolinate synthase signature 31 52 1.7E-8 T 12-10-2018 IPR002220 DapA-like GO:0016829 TSC_c08910 053d03eb398b3813fb34a7b5781a9b06 284 PIRSF PIRSF001365 1 283 2.8E-63 T 12-10-2018 IPR002220 DapA-like GO:0016829 TSC_c08910 053d03eb398b3813fb34a7b5781a9b06 284 Gene3D G3DSA:3.20.20.70 1 284 6.0E-107 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c08910 053d03eb398b3813fb34a7b5781a9b06 284 SMART SM01130 1 278 1.9E-61 T 12-10-2018 IPR002220 DapA-like GO:0016829 TSC_c12210 fe63c6ff36cb6336f02a0bf3669bf682 158 PRINTS PR00601 Bacterioferritin signature 3 22 3.6E-43 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSC_c12210 fe63c6ff36cb6336f02a0bf3669bf682 158 PRINTS PR00601 Bacterioferritin signature 128 149 3.6E-43 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSC_c12210 fe63c6ff36cb6336f02a0bf3669bf682 158 PRINTS PR00601 Bacterioferritin signature 86 106 3.6E-43 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSC_c12210 fe63c6ff36cb6336f02a0bf3669bf682 158 PRINTS PR00601 Bacterioferritin signature 23 43 3.6E-43 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSC_c12210 fe63c6ff36cb6336f02a0bf3669bf682 158 PRINTS PR00601 Bacterioferritin signature 65 85 3.6E-43 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSC_c12210 fe63c6ff36cb6336f02a0bf3669bf682 158 PRINTS PR00601 Bacterioferritin signature 44 64 3.6E-43 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSC_c12210 fe63c6ff36cb6336f02a0bf3669bf682 158 PRINTS PR00601 Bacterioferritin signature 107 127 3.6E-43 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSC_c12210 fe63c6ff36cb6336f02a0bf3669bf682 158 SUPERFAMILY SSF47240 1 154 1.59E-45 T 12-10-2018 IPR009078 Ferritin-like superfamily TSC_c12210 fe63c6ff36cb6336f02a0bf3669bf682 158 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSC_c12210 fe63c6ff36cb6336f02a0bf3669bf682 158 PIRSF PIRSF002560 1 157 7.0E-57 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSC_c12210 fe63c6ff36cb6336f02a0bf3669bf682 158 TIGRFAM TIGR00754 bfr: bacterioferritin 1 153 6.7E-51 T 12-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 TSC_c12210 fe63c6ff36cb6336f02a0bf3669bf682 158 Gene3D G3DSA:1.20.1260.10 1 156 2.3E-57 T 12-10-2018 IPR012347 Ferritin-like TSC_c12210 fe63c6ff36cb6336f02a0bf3669bf682 158 Pfam PF00210 Ferritin-like domain 8 144 1.5E-32 T 12-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 TSC_c20840 0d08267436c281264f6ebeafe3862a19 485 Pfam PF03853 YjeF-related protein N-terminus 30 177 4.3E-29 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TSC_c20840 0d08267436c281264f6ebeafe3862a19 485 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 216 470 9.2E-55 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TSC_c20840 0d08267436c281264f6ebeafe3862a19 485 Pfam PF01256 Carbohydrate kinase 245 468 1.0E-45 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TSC_c20840 0d08267436c281264f6ebeafe3862a19 485 Gene3D G3DSA:3.40.50.10260 3 203 1.9E-50 T 12-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 TSC_c20840 0d08267436c281264f6ebeafe3862a19 485 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 412 422 - T 12-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site TSC_c20840 0d08267436c281264f6ebeafe3862a19 485 Gene3D G3DSA:3.40.1190.20 207 473 1.3E-74 T 12-10-2018 IPR029056 Ribokinase-like TSC_c20840 0d08267436c281264f6ebeafe3862a19 485 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 9 197 22.088 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TSC_c20840 0d08267436c281264f6ebeafe3862a19 485 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 9 198 1.9E-34 T 12-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 TSC_c20840 0d08267436c281264f6ebeafe3862a19 485 SUPERFAMILY SSF64153 6 233 1.44E-55 T 12-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 TSC_c20840 0d08267436c281264f6ebeafe3862a19 485 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 211 476 21.303 T 12-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 TSC_c20840 0d08267436c281264f6ebeafe3862a19 485 PIRSF PIRSF017184 5 479 2.2E-105 T 12-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 TSC_c20840 0d08267436c281264f6ebeafe3862a19 485 SUPERFAMILY SSF53613 211 471 8.26E-64 T 12-10-2018 IPR029056 Ribokinase-like TSC_c21130 6779d2f25071d280ddcd3ffd079c9d2b 148 SUPERFAMILY SSF46626 19 131 1.17E-25 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c21130 6779d2f25071d280ddcd3ffd079c9d2b 148 Pfam PF00034 Cytochrome c 19 107 1.1E-10 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c21130 6779d2f25071d280ddcd3ffd079c9d2b 148 Gene3D G3DSA:1.10.760.10 18 148 2.6E-52 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c12030 b077532040d02abb6d1581d0f3df3c8a 593 Pfam PF14742 N-terminal domain of (some) glycogen debranching enzymes 4 172 2.3E-18 T 12-10-2018 IPR032856 Putative glycogen debranching enzyme, N-terminal TSC_c12030 b077532040d02abb6d1581d0f3df3c8a 593 Gene3D G3DSA:1.50.10.10 215 586 3.8E-46 T 12-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 TSC_c12030 b077532040d02abb6d1581d0f3df3c8a 593 SUPERFAMILY SSF48208 212 584 6.05E-70 T 12-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 TSC_c01110 de1ad27b0e5e1fb19d4ced17eb065c9b 372 Pfam PF03054 tRNA methyl transferase 3 350 4.2E-113 T 12-10-2018 TSC_c01110 de1ad27b0e5e1fb19d4ced17eb065c9b 372 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 3 350 8.6E-95 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 TSC_c01110 de1ad27b0e5e1fb19d4ced17eb065c9b 372 Gene3D G3DSA:2.40.30.10 281 357 1.3E-17 T 12-10-2018 TSC_c01110 de1ad27b0e5e1fb19d4ced17eb065c9b 372 Gene3D G3DSA:3.40.50.620 1 213 4.9E-77 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c01110 de1ad27b0e5e1fb19d4ced17eb065c9b 372 SUPERFAMILY SSF52402 2 247 2.43E-49 T 12-10-2018 TSC_c01110 de1ad27b0e5e1fb19d4ced17eb065c9b 372 Gene3D G3DSA:2.30.30.280 216 278 2.0E-14 T 12-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 TSC_c01110 de1ad27b0e5e1fb19d4ced17eb065c9b 372 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 2 351 39.622 T 12-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 TSC_c01270 50710f57648afaf2f1f5a4195f207871 353 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 117 126 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TSC_c01270 50710f57648afaf2f1f5a4195f207871 353 SUPERFAMILY SSF53187 96 340 1.13E-20 T 12-10-2018 TSC_c01270 50710f57648afaf2f1f5a4195f207871 353 Pfam PF04389 Peptidase family M28 186 335 1.2E-12 T 12-10-2018 IPR007484 Peptidase M28 TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 Gene3D G3DSA:1.10.730.10 477 592 2.9E-36 T 12-10-2018 TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 SMART SM00836 473 592 3.1E-31 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 SMART SM01016 2 82 2.8E-18 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 Gene3D G3DSA:3.40.50.620 104 476 9.3E-110 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 114 123 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 SUPERFAMILY SSF47323 467 592 1.24E-30 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 PRINTS PR01038 Arginyl-tRNA synthetase signature 119 135 4.3E-19 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 PRINTS PR01038 Arginyl-tRNA synthetase signature 143 156 4.3E-19 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 PRINTS PR01038 Arginyl-tRNA synthetase signature 291 312 4.3E-19 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 PRINTS PR01038 Arginyl-tRNA synthetase signature 104 119 4.3E-19 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 Pfam PF00750 tRNA synthetases class I (R) 345 450 2.7E-9 T 12-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 Pfam PF00750 tRNA synthetases class I (R) 104 307 1.2E-11 T 12-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 6 82 2.3E-14 T 12-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 Gene3D G3DSA:3.30.1360.70 1 99 4.7E-20 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 SUPERFAMILY SSF52374 98 466 2.7E-71 T 12-10-2018 TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 SUPERFAMILY SSF55190 3 91 5.23E-18 T 12-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 Hamap MF_00123 Arginine--tRNA ligase [argS]. 4 592 22.383 T 12-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 TSC_c18660 30eb289927afd54a7c9d4114ef118694 592 Pfam PF05746 DALR anticodon binding domain 473 592 8.1E-30 T 12-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 TSC_c13550 15e551c5868b6f836e9d68e33f36eb9c 378 Pfam PF07690 Major Facilitator Superfamily 25 289 7.8E-16 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c13550 15e551c5868b6f836e9d68e33f36eb9c 378 Gene3D G3DSA:1.20.1250.20 2 373 3.3E-26 T 12-10-2018 TSC_c13550 15e551c5868b6f836e9d68e33f36eb9c 378 SUPERFAMILY SSF103473 13 373 1.31E-32 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c13580 5a4fefe0f8259bb2e90632f060e89fb8 74 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 41 2.5E-10 T 12-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TSC_c13580 5a4fefe0f8259bb2e90632f060e89fb8 74 SUPERFAMILY SSF47598 1 45 2.51E-9 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TSC_c13580 5a4fefe0f8259bb2e90632f060e89fb8 74 Gene3D G3DSA:1.10.1220.10 2 43 2.8E-5 T 12-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 TSC_c19870 ca23b955d50835a59db24ac64579d137 573 Pfam PF12831 FAD dependent oxidoreductase 23 413 2.6E-76 T 12-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal TSC_c19870 ca23b955d50835a59db24ac64579d137 573 SUPERFAMILY SSF51905 21 411 8.46E-20 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c19870 ca23b955d50835a59db24ac64579d137 573 Gene3D G3DSA:3.50.50.60 19 179 1.1E-12 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c17500 3c5afe2bcb7089d82b84d046c009814c 511 Gene3D G3DSA:1.10.3650.10 383 454 4.9E-14 T 12-10-2018 IPR038262 Nitrate reductase beta, C-terminal domain superfamily KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 TSC_c17500 3c5afe2bcb7089d82b84d046c009814c 511 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 391 455 3.4E-17 T 12-10-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 TSC_c17500 3c5afe2bcb7089d82b84d046c009814c 511 Pfam PF13247 4Fe-4S dicluster domain 176 272 3.1E-36 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c17500 3c5afe2bcb7089d82b84d046c009814c 511 Gene3D G3DSA:3.30.70.20 1 295 2.2E-92 T 12-10-2018 TSC_c17500 3c5afe2bcb7089d82b84d046c009814c 511 SUPERFAMILY SSF54862 1 487 1.17E-138 T 12-10-2018 TSC_c17500 3c5afe2bcb7089d82b84d046c009814c 511 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 491 2.3E-191 T 12-10-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 TSC_c08420 1ef9a3affdc2c7dbd36d47ddb81f2fb8 518 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 5 495 1.3E-204 T 12-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSC_c08420 1ef9a3affdc2c7dbd36d47ddb81f2fb8 518 Gene3D G3DSA:1.10.238.260 280 393 4.2E-36 T 12-10-2018 TSC_c08420 1ef9a3affdc2c7dbd36d47ddb81f2fb8 518 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 12 28 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSC_c08420 1ef9a3affdc2c7dbd36d47ddb81f2fb8 518 Pfam PF00682 HMGL-like 5 273 2.3E-92 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TSC_c08420 1ef9a3affdc2c7dbd36d47ddb81f2fb8 518 Gene3D G3DSA:3.20.20.70 2 276 2.2E-106 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c08420 1ef9a3affdc2c7dbd36d47ddb81f2fb8 518 SUPERFAMILY SSF110921 393 497 3.66E-21 T 12-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSC_c08420 1ef9a3affdc2c7dbd36d47ddb81f2fb8 518 Pfam PF08502 LeuA allosteric (dimerisation) domain 372 498 4.2E-30 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSC_c08420 1ef9a3affdc2c7dbd36d47ddb81f2fb8 518 SUPERFAMILY SSF51569 1 291 2.2E-95 T 12-10-2018 TSC_c08420 1ef9a3affdc2c7dbd36d47ddb81f2fb8 518 SMART SM00917 370 500 6.0E-32 T 12-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSC_c08420 1ef9a3affdc2c7dbd36d47ddb81f2fb8 518 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 2 509 40.636 T 12-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSC_c08420 1ef9a3affdc2c7dbd36d47ddb81f2fb8 518 Gene3D G3DSA:3.30.160.270 394 500 8.8E-7 T 12-10-2018 TSC_c08420 1ef9a3affdc2c7dbd36d47ddb81f2fb8 518 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 199 212 - T 12-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 TSC_c23580 38adfe24d7744db6dd37a94ac76ffd00 319 Gene3D G3DSA:1.25.40.10 178 312 1.5E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c23580 38adfe24d7744db6dd37a94ac76ffd00 319 SUPERFAMILY SSF48452 224 298 9.49E-7 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c22980 7bc0af2d2fa210f8a41c34714cc62ea2 146 Pfam PF05168 HEPN domain 18 138 6.0E-31 T 12-10-2018 IPR007842 HEPN domain TSC_c22980 7bc0af2d2fa210f8a41c34714cc62ea2 146 SMART SM00748 20 132 2.6E-33 T 12-10-2018 IPR007842 HEPN domain TSC_c22980 7bc0af2d2fa210f8a41c34714cc62ea2 146 SUPERFAMILY SSF81593 14 139 5.89E-39 T 12-10-2018 TSC_c22980 7bc0af2d2fa210f8a41c34714cc62ea2 146 Gene3D G3DSA:1.20.120.330 12 141 8.9E-37 T 12-10-2018 TSC_c10420 2d92cf7621b5c8730f7b9631e8525531 296 PIRSF PIRSF001365 1 294 7.4E-82 T 12-10-2018 IPR002220 DapA-like GO:0016829 TSC_c10420 2d92cf7621b5c8730f7b9631e8525531 296 TIGRFAM TIGR02313 HpaI-NOT-DapA: 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase 2 292 9.1E-164 T 12-10-2018 IPR012691 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase variant GO:0005737|GO:0008840|GO:0019877 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSC_c10420 2d92cf7621b5c8730f7b9631e8525531 296 SUPERFAMILY SSF51569 1 289 3.56E-94 T 12-10-2018 TSC_c10420 2d92cf7621b5c8730f7b9631e8525531 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 70 88 2.2E-26 T 12-10-2018 IPR002220 DapA-like GO:0016829 TSC_c10420 2d92cf7621b5c8730f7b9631e8525531 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 2.2E-26 T 12-10-2018 IPR002220 DapA-like GO:0016829 TSC_c10420 2d92cf7621b5c8730f7b9631e8525531 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 102 118 2.2E-26 T 12-10-2018 IPR002220 DapA-like GO:0016829 TSC_c10420 2d92cf7621b5c8730f7b9631e8525531 296 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 2.2E-26 T 12-10-2018 IPR002220 DapA-like GO:0016829 TSC_c10420 2d92cf7621b5c8730f7b9631e8525531 296 Pfam PF00701 Dihydrodipicolinate synthetase family 2 285 7.6E-81 T 12-10-2018 IPR002220 DapA-like GO:0016829 TSC_c10420 2d92cf7621b5c8730f7b9631e8525531 296 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 288 56.361 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSC_c10420 2d92cf7621b5c8730f7b9631e8525531 296 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 6 286 4.8E-83 T 12-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 TSC_c10420 2d92cf7621b5c8730f7b9631e8525531 296 Gene3D G3DSA:3.20.20.70 1 292 2.3E-104 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c10420 2d92cf7621b5c8730f7b9631e8525531 296 SMART SM01130 1 290 5.7E-121 T 12-10-2018 IPR002220 DapA-like GO:0016829 TSC_c10420 2d92cf7621b5c8730f7b9631e8525531 296 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 164 - T 12-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 453 479 - T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 Pfam PF00140 Sigma-70 factor, region 1.2 150 183 1.8E-16 T 12-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 Gene3D G3DSA:1.20.120.1810 145 327 1.4E-79 T 12-10-2018 TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 SUPERFAMILY SSF88946 147 328 9.81E-58 T 12-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 SUPERFAMILY SSF88659 390 482 1.1E-28 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 41 494 33.331 T 12-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 254 493 1.8E-115 T 12-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 Gene3D G3DSA:1.10.10.10 331 409 1.0E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 SUPERFAMILY SSF88659 331 407 1.44E-19 T 12-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 Pfam PF04545 Sigma-70, region 4 428 480 3.0E-18 T 12-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 Pfam PF04539 Sigma-70 region 3 337 415 2.3E-25 T 12-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 Gene3D G3DSA:1.10.10.10 410 491 1.3E-33 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 PRINTS PR00046 Major sigma-70 factor signature 282 295 3.3E-27 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 PRINTS PR00046 Major sigma-70 factor signature 432 444 3.3E-27 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 PRINTS PR00046 Major sigma-70 factor signature 453 468 3.3E-27 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 PRINTS PR00046 Major sigma-70 factor signature 468 479 3.3E-27 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 PRINTS PR00046 Major sigma-70 factor signature 306 314 3.3E-27 T 12-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 254 480 8.8E-39 T 12-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 TSC_c07030 102643c5fd608f7744600dd5a41479c0 494 Pfam PF04542 Sigma-70 region 2 258 327 5.2E-20 T 12-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 TSC_c17130 4fd65a6f6f57cf52af01dd692e7fef0d 347 Pfam PF04285 Protein of unknown function (DUF444) 160 345 3.0E-49 T 12-10-2018 IPR006698 Uncharacterised protein family UPF0229 TSC_c17130 4fd65a6f6f57cf52af01dd692e7fef0d 347 Pfam PF04285 Protein of unknown function (DUF444) 7 146 5.9E-10 T 12-10-2018 IPR006698 Uncharacterised protein family UPF0229 TSC_c17130 4fd65a6f6f57cf52af01dd692e7fef0d 347 SUPERFAMILY SSF53300 179 291 3.59E-8 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSC_c16330 c1efce014707d37325a15b645fe5cebe 820 Pfam PF01935 Domain of unknown function DUF87 419 544 4.3E-8 T 12-10-2018 IPR002789 Helicase HerA, central domain TSC_c16330 c1efce014707d37325a15b645fe5cebe 820 SUPERFAMILY SSF52540 395 743 4.91E-35 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c16330 c1efce014707d37325a15b645fe5cebe 820 Pfam PF11130 F pilus assembly Type-IV secretion system for plasmid transfer 13 197 1.5E-6 T 12-10-2018 IPR025955 Type-IV secretion system protein TraC/Conjugative transfer ATPase TSC_c16330 c1efce014707d37325a15b645fe5cebe 820 Pfam PF12846 AAA-like domain 655 706 1.7E-7 T 12-10-2018 TSC_c16330 c1efce014707d37325a15b645fe5cebe 820 Gene3D G3DSA:1.10.8.730 491 626 8.1E-34 T 12-10-2018 TSC_c16330 c1efce014707d37325a15b645fe5cebe 820 Gene3D G3DSA:3.40.50.300 422 769 8.1E-34 T 12-10-2018 TSC_c00410 b49f65677c1a47210870561c7aa2b812 152 SUPERFAMILY SSF69765 1 150 7.33E-47 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TSC_c00410 b49f65677c1a47210870561c7aa2b812 152 Gene3D G3DSA:3.30.1330.50 1 152 3.0E-51 T 12-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TSC_c00410 b49f65677c1a47210870561c7aa2b812 152 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 150 2.4E-48 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TSC_c00410 b49f65677c1a47210870561c7aa2b812 152 Pfam PF02542 YgbB family 1 150 2.7E-46 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TSC_c00410 b49f65677c1a47210870561c7aa2b812 152 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 152 30.283 T 12-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 TSC_c04980 0fb07a038aa0a192cdaf5634cf0e423e 584 Pfam PF00664 ABC transporter transmembrane region 27 292 1.1E-46 T 12-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 TSC_c04980 0fb07a038aa0a192cdaf5634cf0e423e 584 SMART SM00382 364 556 5.9E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c04980 0fb07a038aa0a192cdaf5634cf0e423e 584 Gene3D G3DSA:3.40.50.300 335 582 2.0E-78 T 12-10-2018 TSC_c04980 0fb07a038aa0a192cdaf5634cf0e423e 584 Pfam PF00005 ABC transporter 355 503 3.3E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c04980 0fb07a038aa0a192cdaf5634cf0e423e 584 Gene3D G3DSA:1.20.1560.10 6 322 5.1E-79 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSC_c04980 0fb07a038aa0a192cdaf5634cf0e423e 584 SUPERFAMILY SSF90123 12 328 5.36E-73 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSC_c04980 0fb07a038aa0a192cdaf5634cf0e423e 584 ProSitePatterns PS00211 ABC transporters family signature. 476 490 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c04980 0fb07a038aa0a192cdaf5634cf0e423e 584 SUPERFAMILY SSF52540 334 574 5.01E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c22560 39f7aa43f1e97ef474438a9e303c43c5 369 Gene3D G3DSA:3.40.50.720 128 303 1.1E-140 T 12-10-2018 TSC_c22560 39f7aa43f1e97ef474438a9e303c43c5 369 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 135 1.7E-44 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TSC_c22560 39f7aa43f1e97ef474438a9e303c43c5 369 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 139 349 9.4E-87 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TSC_c22560 39f7aa43f1e97ef474438a9e303c43c5 369 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 171 196 - T 12-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 TSC_c22560 39f7aa43f1e97ef474438a9e303c43c5 369 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 367 1.1E-170 T 12-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 TSC_c22560 39f7aa43f1e97ef474438a9e303c43c5 369 SMART SM01003 4 135 1.6E-78 T 12-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal TSC_c22560 39f7aa43f1e97ef474438a9e303c43c5 369 Gene3D G3DSA:3.40.50.720 3 349 1.1E-140 T 12-10-2018 TSC_c22560 39f7aa43f1e97ef474438a9e303c43c5 369 SUPERFAMILY SSF52283 1 357 7.74E-68 T 12-10-2018 TSC_c22560 39f7aa43f1e97ef474438a9e303c43c5 369 PIRSF PIRSF000183 1 368 8.0E-187 T 12-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 TSC_c22560 39f7aa43f1e97ef474438a9e303c43c5 369 SUPERFAMILY SSF51735 135 301 4.03E-50 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c22560 39f7aa43f1e97ef474438a9e303c43c5 369 SMART SM01002 147 295 3.9E-89 T 12-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain TSC_c07290 b1f65da41307d311778c848c2dc351a2 196 Pfam PF02660 Glycerol-3-phosphate acyltransferase 25 185 5.8E-16 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TSC_c07290 b1f65da41307d311778c848c2dc351a2 196 SMART SM01207 24 189 1.4E-13 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TSC_c04290 f604a1147cdc9d0aacaba19ef69d6d86 500 SUPERFAMILY SSF161098 13 248 1.64E-34 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c04290 f604a1147cdc9d0aacaba19ef69d6d86 500 SUPERFAMILY SSF161098 262 494 3.36E-34 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c04290 f604a1147cdc9d0aacaba19ef69d6d86 500 Gene3D G3DSA:1.10.3720.10 263 498 3.1E-32 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c04290 f604a1147cdc9d0aacaba19ef69d6d86 500 Gene3D G3DSA:1.10.3720.10 9 249 2.7E-37 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c04290 f604a1147cdc9d0aacaba19ef69d6d86 500 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 344 485 4.1E-7 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c25050 3af892c4b155a2f97168dff3050debc7 246 Pfam PF02527 rRNA small subunit methyltransferase G 31 211 2.4E-42 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TSC_c25050 3af892c4b155a2f97168dff3050debc7 246 Gene3D G3DSA:3.40.50.150 5 246 1.2E-80 T 12-10-2018 TSC_c25050 3af892c4b155a2f97168dff3050debc7 246 PIRSF PIRSF003078 14 228 2.8E-47 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TSC_c25050 3af892c4b155a2f97168dff3050debc7 246 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 23 222 26.039 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TSC_c25050 3af892c4b155a2f97168dff3050debc7 246 SUPERFAMILY SSF53335 28 245 2.5E-37 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c25050 3af892c4b155a2f97168dff3050debc7 246 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 34 223 3.2E-45 T 12-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 TSC_c10680 c91fcbbf0d03074a94acd0845c3df855 269 SUPERFAMILY SSF102198 44 268 1.57E-58 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TSC_c10680 c91fcbbf0d03074a94acd0845c3df855 269 Pfam PF04199 Putative cyclase 46 211 1.6E-35 T 12-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TSC_c10680 c91fcbbf0d03074a94acd0845c3df855 269 Gene3D G3DSA:3.50.30.50 29 269 1.1E-80 T 12-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 TSC_c13660 0d351f2fe32938c424af17dbeaafebf4 381 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 203 377 6.3E-15 T 12-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 TSC_c13660 0d351f2fe32938c424af17dbeaafebf4 381 SUPERFAMILY SSF53187 201 380 4.71E-18 T 12-10-2018 TSC_c13660 0d351f2fe32938c424af17dbeaafebf4 381 Gene3D G3DSA:3.40.630.40 195 381 5.6E-20 T 12-10-2018 TSC_c13800 7a75a0b348b07d360cf7cfade1c9957d 183 Pfam PF05977 Transmembrane secretion effector 15 181 1.3E-10 T 12-10-2018 IPR010290 Transmembrane secretion effector TSC_c13800 7a75a0b348b07d360cf7cfade1c9957d 183 SUPERFAMILY SSF103473 9 179 1.7E-15 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c13800 7a75a0b348b07d360cf7cfade1c9957d 183 Gene3D G3DSA:1.20.1250.20 2 181 5.6E-11 T 12-10-2018 TSC_c05620 334cb35a8940ae9265b19345d049f460 304 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 29 302 4.1E-99 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TSC_c05620 334cb35a8940ae9265b19345d049f460 304 SMART SM00962 102 303 3.6E-113 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSC_c05620 334cb35a8940ae9265b19345d049f460 304 Gene3D G3DSA:3.40.50.300 97 304 4.3E-77 T 12-10-2018 TSC_c05620 334cb35a8940ae9265b19345d049f460 304 SMART SM00963 7 76 1.2E-9 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSC_c05620 334cb35a8940ae9265b19345d049f460 304 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 276 289 - T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSC_c05620 334cb35a8940ae9265b19345d049f460 304 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 26 303 59.825 T 12-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 TSC_c05620 334cb35a8940ae9265b19345d049f460 304 SMART SM00382 101 281 1.6E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c05620 334cb35a8940ae9265b19345d049f460 304 Gene3D G3DSA:1.20.120.140 22 96 3.8E-40 T 12-10-2018 TSC_c05620 334cb35a8940ae9265b19345d049f460 304 Pfam PF02881 SRP54-type protein, helical bundle domain 29 70 1.3E-7 T 12-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSC_c05620 334cb35a8940ae9265b19345d049f460 304 Pfam PF00448 SRP54-type protein, GTPase domain 104 302 1.1E-74 T 12-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 TSC_c05620 334cb35a8940ae9265b19345d049f460 304 SUPERFAMILY SSF52540 98 303 4.0E-50 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c05620 334cb35a8940ae9265b19345d049f460 304 SUPERFAMILY SSF47364 22 78 3.53E-16 T 12-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 TSC_c23750 1fad14ad0163ff877dff594b272d4ae0 232 SUPERFAMILY SSF53474 3 224 4.27E-34 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c23750 1fad14ad0163ff877dff594b272d4ae0 232 Pfam PF12146 Serine aminopeptidase, S33 3 212 1.4E-20 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 TSC_c23750 1fad14ad0163ff877dff594b272d4ae0 232 Gene3D G3DSA:3.40.50.1820 2 225 7.8E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c23750 1fad14ad0163ff877dff594b272d4ae0 232 PIRSF PIRSF017388 2 228 7.2E-45 T 12-10-2018 IPR012354 Esterase/lipase GO:0052689 TSC_p800060 e62232a5b99aebcf5a0d14f15a40cbf4 319 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 86 8.9E-11 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSC_p800060 e62232a5b99aebcf5a0d14f15a40cbf4 319 Gene3D G3DSA:3.40.50.720 121 263 2.0E-118 T 12-10-2018 TSC_p800060 e62232a5b99aebcf5a0d14f15a40cbf4 319 Pfam PF00107 Zinc-binding dehydrogenase 149 251 3.1E-26 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSC_p800060 e62232a5b99aebcf5a0d14f15a40cbf4 319 SMART SM00829 10 317 1.1E-31 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSC_p800060 e62232a5b99aebcf5a0d14f15a40cbf4 319 SUPERFAMILY SSF50129 1 142 1.83E-43 T 12-10-2018 IPR011032 GroES-like superfamily TSC_p800060 e62232a5b99aebcf5a0d14f15a40cbf4 319 Gene3D G3DSA:3.90.180.10 9 316 2.0E-118 T 12-10-2018 TSC_p800060 e62232a5b99aebcf5a0d14f15a40cbf4 319 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 138 159 - T 12-10-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 TSC_p800060 e62232a5b99aebcf5a0d14f15a40cbf4 319 SUPERFAMILY SSF51735 109 271 1.69E-43 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c11350 024e0e507d6eff0fc5f520339bddee4e 414 SMART SM00327 53 227 9.0E-28 T 12-10-2018 IPR002035 von Willebrand factor, type A TSC_c11350 024e0e507d6eff0fc5f520339bddee4e 414 Gene3D G3DSA:3.40.50.410 56 228 4.8E-38 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSC_c11350 024e0e507d6eff0fc5f520339bddee4e 414 Pfam PF00092 von Willebrand factor type A domain 55 225 9.2E-22 T 12-10-2018 IPR002035 von Willebrand factor, type A TSC_c11350 024e0e507d6eff0fc5f520339bddee4e 414 SUPERFAMILY SSF53300 50 226 4.84E-39 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSC_c04750 46aca8a6c9b60b3f282676134d8d39e2 528 SUPERFAMILY SSF52540 1 317 1.02E-30 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c04750 46aca8a6c9b60b3f282676134d8d39e2 528 Gene3D G3DSA:3.40.50.300 1 336 2.7E-29 T 12-10-2018 TSC_c04750 46aca8a6c9b60b3f282676134d8d39e2 528 Pfam PF13175 AAA ATPase domain 136 314 5.8E-24 T 12-10-2018 TSC_c04750 46aca8a6c9b60b3f282676134d8d39e2 528 Pfam PF13175 AAA ATPase domain 1 76 3.0E-14 T 12-10-2018 TSC_c17530 95a217bc0b4beefe8198c0dd19d41191 602 Pfam PF03704 Bacterial transcriptional activator domain 500 597 5.8E-11 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TSC_c17530 95a217bc0b4beefe8198c0dd19d41191 602 Gene3D G3DSA:1.10.10.10 396 495 9.5E-14 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c17530 95a217bc0b4beefe8198c0dd19d41191 602 SUPERFAMILY SSF48452 500 598 1.9E-11 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c17530 95a217bc0b4beefe8198c0dd19d41191 602 SUPERFAMILY SSF46894 405 481 7.94E-7 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSC_c17530 95a217bc0b4beefe8198c0dd19d41191 602 SUPERFAMILY SSF55781 104 255 2.16E-17 T 12-10-2018 TSC_c17530 95a217bc0b4beefe8198c0dd19d41191 602 SMART SM01043 500 598 1.5E-9 T 12-10-2018 IPR005158 Bacterial transcriptional activator domain TSC_c17530 95a217bc0b4beefe8198c0dd19d41191 602 SMART SM00065 117 262 0.0019 T 12-10-2018 IPR003018 GAF domain GO:0005515 TSC_c17530 95a217bc0b4beefe8198c0dd19d41191 602 Pfam PF13185 GAF domain 120 253 1.1E-7 T 12-10-2018 IPR003018 GAF domain GO:0005515 TSC_c17530 95a217bc0b4beefe8198c0dd19d41191 602 Gene3D G3DSA:3.30.450.40 100 257 2.1E-18 T 12-10-2018 IPR029016 GAF-like domain superfamily TSC_c17530 95a217bc0b4beefe8198c0dd19d41191 602 Gene3D G3DSA:1.25.40.10 499 599 7.4E-14 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c06120 d79cccb947aa93e6a3d7b32ba03b58e1 631 SUPERFAMILY SSF48452 245 413 9.02E-20 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c06120 d79cccb947aa93e6a3d7b32ba03b58e1 631 Gene3D G3DSA:1.25.40.10 187 422 3.2E-22 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c06120 d79cccb947aa93e6a3d7b32ba03b58e1 631 SMART SM00028 319 351 26.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c06120 d79cccb947aa93e6a3d7b32ba03b58e1 631 SMART SM00028 285 318 0.17 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c06120 d79cccb947aa93e6a3d7b32ba03b58e1 631 SMART SM00028 251 284 52.0 T 12-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 TSC_c16520 d66ef77a313e1d2272d1be9b08dd65e6 382 Gene3D G3DSA:1.20.5.340 66 259 2.6E-7 T 12-10-2018 TSC_c16520 d66ef77a313e1d2272d1be9b08dd65e6 382 SUPERFAMILY SSF58100 84 245 3.92E-5 T 12-10-2018 TSC_c16520 d66ef77a313e1d2272d1be9b08dd65e6 382 Pfam PF00395 S-layer homology domain 18 54 7.4E-5 T 12-10-2018 IPR001119 S-layer homology domain TSC_c17160 55356b049807fabdc9ef259799780e3a 125 ProSitePatterns PS00380 Rhodanese signature 1. 52 63 - T 12-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 TSC_c17160 55356b049807fabdc9ef259799780e3a 125 Gene3D G3DSA:3.40.250.10 29 125 6.9E-33 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c17160 55356b049807fabdc9ef259799780e3a 125 Pfam PF00581 Rhodanese-like domain 30 116 2.2E-19 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c17160 55356b049807fabdc9ef259799780e3a 125 SMART SM00450 28 122 2.1E-27 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c17160 55356b049807fabdc9ef259799780e3a 125 SUPERFAMILY SSF52821 12 125 8.12E-38 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c07990 03eb81a79ac2029b84845bb9cdaad618 775 SMART SM00490 581 665 2.7E-23 T 12-10-2018 IPR001650 Helicase, C-terminal TSC_c07990 03eb81a79ac2029b84845bb9cdaad618 775 Gene3D G3DSA:3.40.50.300 330 533 2.9E-82 T 12-10-2018 TSC_c07990 03eb81a79ac2029b84845bb9cdaad618 775 SUPERFAMILY SSF52540 276 530 4.02E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c07990 03eb81a79ac2029b84845bb9cdaad618 775 Pfam PF00270 DEAD/DEAH box helicase 351 508 5.6E-15 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSC_c07990 03eb81a79ac2029b84845bb9cdaad618 775 Gene3D G3DSA:2.40.50.140 137 233 3.7E-15 T 12-10-2018 TSC_c07990 03eb81a79ac2029b84845bb9cdaad618 775 Pfam PF00271 Helicase conserved C-terminal domain 552 665 3.8E-20 T 12-10-2018 IPR001650 Helicase, C-terminal TSC_c07990 03eb81a79ac2029b84845bb9cdaad618 775 SUPERFAMILY SSF50249 109 265 9.42E-38 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c07990 03eb81a79ac2029b84845bb9cdaad618 775 SUPERFAMILY SSF52540 529 729 7.35E-43 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c07990 03eb81a79ac2029b84845bb9cdaad618 775 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 119 739 5.6E-218 T 12-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 TSC_c07990 03eb81a79ac2029b84845bb9cdaad618 775 Gene3D G3DSA:3.40.50.300 534 705 1.4E-57 T 12-10-2018 TSC_c07990 03eb81a79ac2029b84845bb9cdaad618 775 Pfam PF17191 RecG wedge domain 108 261 1.4E-21 T 12-10-2018 IPR033454 RecG, wedge domain TSC_c07990 03eb81a79ac2029b84845bb9cdaad618 775 SMART SM00487 345 536 2.0E-31 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSC_c17750 86faeea13c60938a7f04169c5080564c 93 Pfam PF00037 4Fe-4S binding domain 38 60 6.4E-10 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c17750 86faeea13c60938a7f04169c5080564c 93 PRINTS PR00354 7Fe ferredoxin signature 13 23 6.1E-15 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSC_c17750 86faeea13c60938a7f04169c5080564c 93 PRINTS PR00354 7Fe ferredoxin signature 39 56 6.1E-15 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSC_c17750 86faeea13c60938a7f04169c5080564c 93 PRINTS PR00354 7Fe ferredoxin signature 23 33 6.1E-15 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSC_c17750 86faeea13c60938a7f04169c5080564c 93 Gene3D G3DSA:3.30.70.20 6 91 1.2E-32 T 12-10-2018 TSC_c17750 86faeea13c60938a7f04169c5080564c 93 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 44 55 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c17750 86faeea13c60938a7f04169c5080564c 93 SUPERFAMILY SSF54862 5 88 2.76E-20 T 12-10-2018 TSC_c03640 7649906abf89c7c8395a0de7c9e5814d 260 SUPERFAMILY SSF51366 13 254 3.25E-55 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSC_c03640 7649906abf89c7c8395a0de7c9e5814d 260 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 14 221 1.9E-24 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSC_c03640 7649906abf89c7c8395a0de7c9e5814d 260 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 12 223 2.2E-63 T 12-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c03640 7649906abf89c7c8395a0de7c9e5814d 260 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 5 260 31.612 T 12-10-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c03640 7649906abf89c7c8395a0de7c9e5814d 260 Gene3D G3DSA:3.20.20.70 13 258 1.1E-68 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c03640 7649906abf89c7c8395a0de7c9e5814d 260 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 84 97 - T 12-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSC_c03640 7649906abf89c7c8395a0de7c9e5814d 260 SMART SM00934 14 248 6.9E-19 T 12-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSC_c05100 b0c37de23f41bf28851cf53ac91e2071 446 Gene3D G3DSA:3.30.590.10 110 446 9.5E-139 T 12-10-2018 TSC_c05100 b0c37de23f41bf28851cf53ac91e2071 446 Gene3D G3DSA:3.10.20.70 1 109 3.3E-37 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSC_c05100 b0c37de23f41bf28851cf53ac91e2071 446 SUPERFAMILY SSF54368 4 106 4.58E-29 T 12-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSC_c05100 b0c37de23f41bf28851cf53ac91e2071 446 SUPERFAMILY SSF55931 107 443 4.41E-129 T 12-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 TSC_c05100 b0c37de23f41bf28851cf53ac91e2071 446 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 236 251 - T 12-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TSC_c05100 b0c37de23f41bf28851cf53ac91e2071 446 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 100 1.9E-27 T 12-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TSC_c05100 b0c37de23f41bf28851cf53ac91e2071 446 SMART SM01230 107 356 2.7E-135 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSC_c05100 b0c37de23f41bf28851cf53ac91e2071 446 ProSitePatterns PS00180 Glutamine synthetase signature 1. 51 69 - T 12-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 TSC_c05100 b0c37de23f41bf28851cf53ac91e2071 446 Pfam PF00120 Glutamine synthetase, catalytic domain 108 442 1.9E-138 T 12-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSC_c05100 b0c37de23f41bf28851cf53ac91e2071 446 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 149 443 2.5E-129 T 12-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 TSC_c16820 233ed47f7812dbf008ab70e7d8ee23d2 244 Gene3D G3DSA:3.40.1210.10 1 244 4.6E-91 T 12-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TSC_c16820 233ed47f7812dbf008ab70e7d8ee23d2 244 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 232 5.7E-51 T 12-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TSC_c16820 233ed47f7812dbf008ab70e7d8ee23d2 244 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 244 30.166 T 12-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TSC_c16820 233ed47f7812dbf008ab70e7d8ee23d2 244 Pfam PF01975 Survival protein SurE 3 183 1.5E-45 T 12-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 TSC_c16820 233ed47f7812dbf008ab70e7d8ee23d2 244 SUPERFAMILY SSF64167 1 239 5.75E-69 T 12-10-2018 TSC_c24010 0e21d60209f6c3f505b60a3fdd7e8fc8 202 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 29 202 4.2E-77 T 12-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TSC_c24010 0e21d60209f6c3f505b60a3fdd7e8fc8 202 Gene3D G3DSA:1.10.286.10 18 71 2.5E-23 T 12-10-2018 TSC_c24010 0e21d60209f6c3f505b60a3fdd7e8fc8 202 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 20 202 38.686 T 12-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TSC_c24010 0e21d60209f6c3f505b60a3fdd7e8fc8 202 SUPERFAMILY SSF55620 14 201 8.15E-79 T 12-10-2018 TSC_c24010 0e21d60209f6c3f505b60a3fdd7e8fc8 202 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 81 97 - T 12-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TSC_c24010 0e21d60209f6c3f505b60a3fdd7e8fc8 202 Pfam PF01227 GTP cyclohydrolase I 28 201 3.1E-75 T 12-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 TSC_c24010 0e21d60209f6c3f505b60a3fdd7e8fc8 202 Gene3D G3DSA:3.30.1130.10 72 202 1.4E-64 T 12-10-2018 TSC_c11400 5d62df2d72696d9a253d8bd8bdb4a9bb 219 Gene3D G3DSA:1.10.10.10 2 72 1.3E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c11400 5d62df2d72696d9a253d8bd8bdb4a9bb 219 Gene3D G3DSA:1.20.120.530 74 213 1.2E-32 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSC_c11400 5d62df2d72696d9a253d8bd8bdb4a9bb 219 SUPERFAMILY SSF46785 3 75 6.83E-18 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c11400 5d62df2d72696d9a253d8bd8bdb4a9bb 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 70 1.6E-15 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSC_c11400 5d62df2d72696d9a253d8bd8bdb4a9bb 219 Pfam PF07729 FCD domain 81 204 3.1E-30 T 12-10-2018 IPR011711 GntR, C-terminal TSC_c11400 5d62df2d72696d9a253d8bd8bdb4a9bb 219 SUPERFAMILY SSF48008 77 212 9.68E-32 T 12-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal TSC_c11400 5d62df2d72696d9a253d8bd8bdb4a9bb 219 SMART SM00345 13 71 2.0E-10 T 12-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 TSC_c11400 5d62df2d72696d9a253d8bd8bdb4a9bb 219 SMART SM00895 81 205 7.1E-24 T 12-10-2018 IPR011711 GntR, C-terminal TSC_c06630 d475dc43e06c44843ea8d5b306175bc7 237 SMART SM00862 143 219 3.5E-31 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c06630 d475dc43e06c44843ea8d5b306175bc7 237 Pfam PF00486 Transcriptional regulatory protein, C terminal 143 219 4.2E-29 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c06630 d475dc43e06c44843ea8d5b306175bc7 237 Gene3D G3DSA:3.40.50.2300 1 124 4.0E-32 T 12-10-2018 TSC_c06630 d475dc43e06c44843ea8d5b306175bc7 237 Gene3D G3DSA:1.10.10.10 125 230 5.4E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c06630 d475dc43e06c44843ea8d5b306175bc7 237 SUPERFAMILY SSF52172 3 172 6.39E-35 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c06630 d475dc43e06c44843ea8d5b306175bc7 237 Pfam PF00072 Response regulator receiver domain 4 112 5.7E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c06630 d475dc43e06c44843ea8d5b306175bc7 237 SMART SM00448 2 112 8.2E-37 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c24840 c638fd1300a4e4ebd4f17a2ae5699daf 417 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 113 416 1.4E-97 T 12-10-2018 IPR010119 Gluconeogenesis factor TSC_c24840 c638fd1300a4e4ebd4f17a2ae5699daf 417 SUPERFAMILY SSF142338 110 414 2.62E-86 T 12-10-2018 TSC_c24840 c638fd1300a4e4ebd4f17a2ae5699daf 417 Gene3D G3DSA:3.40.50.12300 108 417 4.9E-107 T 12-10-2018 IPR038136 Gluconeogenesis factor superfamily TSC_c24840 c638fd1300a4e4ebd4f17a2ae5699daf 417 Hamap MF_00973 Gluconeogenesis factor. 109 417 31.622 T 12-10-2018 IPR010119 Gluconeogenesis factor TSC_c24840 c638fd1300a4e4ebd4f17a2ae5699daf 417 Pfam PF01933 Uncharacterised protein family UPF0052 113 395 4.0E-86 T 12-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 TSC_c00890 903fb0e76b61f93e0b3642e6390e1a58 421 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 182 195 - T 12-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c00890 903fb0e76b61f93e0b3642e6390e1a58 421 PRINTS PR00662 Glucose-6-phosphate isomerase signature 250 271 1.4E-21 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c00890 903fb0e76b61f93e0b3642e6390e1a58 421 PRINTS PR00662 Glucose-6-phosphate isomerase signature 69 88 1.4E-21 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c00890 903fb0e76b61f93e0b3642e6390e1a58 421 PRINTS PR00662 Glucose-6-phosphate isomerase signature 178 196 1.4E-21 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c00890 903fb0e76b61f93e0b3642e6390e1a58 421 PRINTS PR00662 Glucose-6-phosphate isomerase signature 390 403 1.4E-21 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c00890 903fb0e76b61f93e0b3642e6390e1a58 421 PRINTS PR00662 Glucose-6-phosphate isomerase signature 358 376 1.4E-21 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c00890 903fb0e76b61f93e0b3642e6390e1a58 421 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 390 407 - T 12-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c00890 903fb0e76b61f93e0b3642e6390e1a58 421 Gene3D G3DSA:3.40.50.10490 204 410 7.7E-126 T 12-10-2018 TSC_c00890 903fb0e76b61f93e0b3642e6390e1a58 421 SUPERFAMILY SSF53697 33 420 8.56E-100 T 12-10-2018 TSC_c00890 903fb0e76b61f93e0b3642e6390e1a58 421 Gene3D G3DSA:3.40.50.10490 66 203 7.7E-126 T 12-10-2018 TSC_c00890 903fb0e76b61f93e0b3642e6390e1a58 421 Pfam PF00342 Phosphoglucose isomerase 66 411 7.2E-35 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c00890 903fb0e76b61f93e0b3642e6390e1a58 421 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 5 417 23.416 T 12-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c24950 693e0e83ccb6efcc689e34c55e648209 272 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 2 215 34.557 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 TSC_c24950 693e0e83ccb6efcc689e34c55e648209 272 Gene3D G3DSA:3.40.1010.10 1 105 1.0E-32 T 12-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 TSC_c24950 693e0e83ccb6efcc689e34c55e648209 272 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 3 260 5.7E-70 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 TSC_c24950 693e0e83ccb6efcc689e34c55e648209 272 SUPERFAMILY SSF53790 3 213 1.83E-73 T 12-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 TSC_c24950 693e0e83ccb6efcc689e34c55e648209 272 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 198 3.8E-30 T 12-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 TSC_c24950 693e0e83ccb6efcc689e34c55e648209 272 PIRSF PIRSF005917 1 264 1.5E-90 T 12-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 TSC_c24950 693e0e83ccb6efcc689e34c55e648209 272 Gene3D G3DSA:3.30.950.10 106 219 1.5E-38 T 12-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 TSC_c12170 b386520977d0886b401186e2bb59908a 252 PIRSF PIRSF037834 2 252 1.9E-95 T 12-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 TSC_c12170 b386520977d0886b401186e2bb59908a 252 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 18 252 4.0E-87 T 12-10-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 TSC_c12170 b386520977d0886b401186e2bb59908a 252 Pfam PF05138 Phenylacetic acid catabolic protein 7 252 1.6E-76 T 12-10-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 TSC_c12170 b386520977d0886b401186e2bb59908a 252 Gene3D G3DSA:1.20.1260.10 2 252 2.3E-84 T 12-10-2018 IPR012347 Ferritin-like TSC_c12170 b386520977d0886b401186e2bb59908a 252 SUPERFAMILY SSF47240 8 244 4.64E-71 T 12-10-2018 IPR009078 Ferritin-like superfamily TSC_c01610 1b9323be63565dd7781e0a969db27621 110 Gene3D G3DSA:3.30.70.120 3 110 1.5E-47 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TSC_c01610 1b9323be63565dd7781e0a969db27621 110 SUPERFAMILY SSF54913 6 105 1.06E-39 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TSC_c01610 1b9323be63565dd7781e0a969db27621 110 Pfam PF02641 Uncharacterized ACR, COG1993 8 104 1.0E-44 T 12-10-2018 IPR003793 Domain of unknown function DUF190 TSC_c23400 e66dc6e402ac95c150db72f59a48c435 570 Pfam PF00128 Alpha amylase, catalytic domain 158 461 1.3E-54 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSC_c23400 e66dc6e402ac95c150db72f59a48c435 570 SMART SM00642 111 499 3.5E-78 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSC_c23400 e66dc6e402ac95c150db72f59a48c435 570 SUPERFAMILY SSF51445 101 508 3.77E-90 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TSC_c23400 e66dc6e402ac95c150db72f59a48c435 570 Gene3D G3DSA:3.20.20.80 100 501 2.6E-114 T 12-10-2018 TSC_c02540 0bbc6daaec9a248f29839b6ff6311e31 179 PIRSF PIRSF014995 12 178 3.4E-32 T 12-10-2018 IPR014469 Protein of unknown function DUF2271 TSC_c02540 0bbc6daaec9a248f29839b6ff6311e31 179 Gene3D G3DSA:2.60.40.4070 95 146 2.3E-5 T 12-10-2018 TSC_c02540 0bbc6daaec9a248f29839b6ff6311e31 179 Pfam PF10029 Predicted periplasmic protein (DUF2271) 40 167 7.0E-28 T 12-10-2018 IPR014469 Protein of unknown function DUF2271 TSC_c02760 8e57f501dc5e13207a9cc8a892c905ab 179 Gene3D G3DSA:3.40.630.30 22 168 7.1E-31 T 12-10-2018 TSC_c02760 8e57f501dc5e13207a9cc8a892c905ab 179 Pfam PF00583 Acetyltransferase (GNAT) family 60 138 7.7E-12 T 12-10-2018 IPR000182 GNAT domain TSC_c02760 8e57f501dc5e13207a9cc8a892c905ab 179 SUPERFAMILY SSF55729 22 150 8.31E-23 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSC_c03090 761a692864efe508ffd3318547cf1bd5 186 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 186 30.346 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 TSC_c03090 761a692864efe508ffd3318547cf1bd5 186 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 5 185 4.3E-47 T 12-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 TSC_c03090 761a692864efe508ffd3318547cf1bd5 186 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 63 5.1E-13 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSC_c03090 761a692864efe508ffd3318547cf1bd5 186 SUPERFAMILY SSF52374 2 185 1.21E-48 T 12-10-2018 TSC_c03090 761a692864efe508ffd3318547cf1bd5 186 Gene3D G3DSA:3.40.50.620 1 186 1.9E-56 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c03090 761a692864efe508ffd3318547cf1bd5 186 Pfam PF01467 Cytidylyltransferase-like 5 160 1.0E-29 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSC_c13150 2d1832acbe9a39d2cc1920f77721d1be 137 Pfam PF00582 Universal stress protein family 1 137 5.9E-36 T 12-10-2018 IPR006016 UspA TSC_c13150 2d1832acbe9a39d2cc1920f77721d1be 137 Gene3D G3DSA:3.40.50.620 1 137 2.8E-47 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c13150 2d1832acbe9a39d2cc1920f77721d1be 137 PRINTS PR01438 Universal stress protein signature 115 137 9.3E-21 T 12-10-2018 IPR006015 Universal stress protein A TSC_c13150 2d1832acbe9a39d2cc1920f77721d1be 137 PRINTS PR01438 Universal stress protein signature 2 20 9.3E-21 T 12-10-2018 IPR006015 Universal stress protein A TSC_c13150 2d1832acbe9a39d2cc1920f77721d1be 137 PRINTS PR01438 Universal stress protein signature 97 109 9.3E-21 T 12-10-2018 IPR006015 Universal stress protein A TSC_c13150 2d1832acbe9a39d2cc1920f77721d1be 137 SUPERFAMILY SSF52402 2 137 1.34E-37 T 12-10-2018 TSC_c05040 b4917f3826dbf037740f32e1a76bf76e 527 Gene3D G3DSA:3.90.76.10 35 198 5.2E-146 T 12-10-2018 TSC_c05040 b4917f3826dbf037740f32e1a76bf76e 527 Gene3D G3DSA:3.40.190.10 199 515 5.2E-146 T 12-10-2018 TSC_c05040 b4917f3826dbf037740f32e1a76bf76e 527 Gene3D G3DSA:3.10.105.10 281 502 5.2E-146 T 12-10-2018 TSC_c05040 b4917f3826dbf037740f32e1a76bf76e 527 PIRSF PIRSF002741 17 526 1.7E-114 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSC_c05040 b4917f3826dbf037740f32e1a76bf76e 527 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 63 441 1.6E-103 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TSC_c05040 b4917f3826dbf037740f32e1a76bf76e 527 SUPERFAMILY SSF53850 19 521 4.71E-140 T 12-10-2018 TSC_c20590 f7a4dad5a764b9ad736be5cf940d1a83 252 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 252 31.622 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 TSC_c20590 f7a4dad5a764b9ad736be5cf940d1a83 252 SUPERFAMILY SSF53067 123 249 2.69E-34 T 12-10-2018 TSC_c20590 f7a4dad5a764b9ad736be5cf940d1a83 252 SUPERFAMILY SSF53067 1 115 8.29E-29 T 12-10-2018 TSC_c20590 f7a4dad5a764b9ad736be5cf940d1a83 252 Pfam PF03309 Type III pantothenate kinase 2 205 1.0E-60 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 TSC_c20590 f7a4dad5a764b9ad736be5cf940d1a83 252 Gene3D G3DSA:3.30.420.40 3 243 6.0E-77 T 12-10-2018 TSC_c20590 f7a4dad5a764b9ad736be5cf940d1a83 252 Gene3D G3DSA:3.30.420.490 123 236 6.0E-77 T 12-10-2018 TSC_c20590 f7a4dad5a764b9ad736be5cf940d1a83 252 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 246 8.2E-62 T 12-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 TSC_c21590 fe2422601c99e02cc2c44f78d2e82608 305 Gene3D G3DSA:1.10.8.300 202 301 5.7E-15 T 12-10-2018 TSC_c21590 fe2422601c99e02cc2c44f78d2e82608 305 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 42 169 2.6E-58 T 12-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 TSC_c21590 fe2422601c99e02cc2c44f78d2e82608 305 Gene3D G3DSA:3.40.50.300 4 201 3.9E-51 T 12-10-2018 TSC_c21590 fe2422601c99e02cc2c44f78d2e82608 305 PIRSF PIRSF002849 1 305 4.2E-106 T 12-10-2018 TSC_c21590 fe2422601c99e02cc2c44f78d2e82608 305 SMART SM00382 39 178 2.5E-7 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c21590 fe2422601c99e02cc2c44f78d2e82608 305 SUPERFAMILY SSF52540 6 277 5.24E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c15890 aae72bfb1ae603c4c6f87b5d9f5c9c4e 198 ProSitePatterns PS01007 Transposases, Mutator family, signature. 19 43 - T 12-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 TSC_c15890 aae72bfb1ae603c4c6f87b5d9f5c9c4e 198 Pfam PF00872 Transposase, Mutator family 1 165 3.4E-38 T 12-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 TSC_c17830 c39e73fd806b82cb21f1610e5416a229 430 Gene3D G3DSA:2.70.70.10 332 430 5.1E-15 T 12-10-2018 IPR011055 Duplicated hybrid motif TSC_c17830 c39e73fd806b82cb21f1610e5416a229 430 Gene3D G3DSA:1.20.5.340 14 136 1.6E-10 T 12-10-2018 TSC_c17830 c39e73fd806b82cb21f1610e5416a229 430 SUPERFAMILY SSF90257 26 129 7.85E-7 T 12-10-2018 TSC_c17830 c39e73fd806b82cb21f1610e5416a229 430 SUPERFAMILY SSF51261 236 400 8.89E-17 T 12-10-2018 IPR011055 Duplicated hybrid motif TSC_c17830 c39e73fd806b82cb21f1610e5416a229 430 Pfam PF01551 Peptidase family M23 337 413 4.9E-13 T 12-10-2018 IPR016047 Peptidase M23 TSC_c18990 52c8229c5d4e3ff1a717befd44dd9109 121 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 2 101 2.4E-18 T 12-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c18990 52c8229c5d4e3ff1a717befd44dd9109 121 Gene3D G3DSA:1.20.1300.10 2 110 8.3E-15 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c18990 52c8229c5d4e3ff1a717befd44dd9109 121 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 2 103 2.4E-17 T 12-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c18990 52c8229c5d4e3ff1a717befd44dd9109 121 SUPERFAMILY SSF81343 2 108 6.76E-21 T 12-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c18990 52c8229c5d4e3ff1a717befd44dd9109 121 PIRSF PIRSF000178 6 111 1.3E-7 T 12-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c16990 04b528ba09f05a5b42795db40861af14 276 Pfam PF01148 Cytidylyltransferase family 9 275 1.2E-58 T 12-10-2018 TSC_c16990 04b528ba09f05a5b42795db40861af14 276 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 233 259 - T 12-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 TSC_c10320 daf7a9d4cbb3847788609979a519eb23 280 Gene3D G3DSA:3.30.1180.10 151 280 7.9E-44 T 12-10-2018 TSC_c10320 daf7a9d4cbb3847788609979a519eb23 280 SUPERFAMILY SSF82549 1 278 3.4E-82 T 12-10-2018 TSC_c10320 daf7a9d4cbb3847788609979a519eb23 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 277 2.9E-92 T 12-10-2018 IPR003797 DegV TSC_c10320 daf7a9d4cbb3847788609979a519eb23 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 278 2.8E-84 T 12-10-2018 IPR003797 DegV TSC_c10320 daf7a9d4cbb3847788609979a519eb23 280 Gene3D G3DSA:3.40.50.10170 1 150 4.4E-59 T 12-10-2018 TSC_c19880 ea7e5df04c059b7642ee6ec0726a4721 284 Gene3D G3DSA:3.20.20.70 2 283 7.4E-73 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c19880 ea7e5df04c059b7642ee6ec0726a4721 284 SUPERFAMILY SSF51412 1 280 2.44E-53 T 12-10-2018 TSC_c19880 ea7e5df04c059b7642ee6ec0726a4721 284 Pfam PF03060 Nitronate monooxygenase 81 233 1.0E-23 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 TSC_c19880 ea7e5df04c059b7642ee6ec0726a4721 284 Pfam PF03060 Nitronate monooxygenase 4 73 9.6E-7 T 12-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 TSC_c06070 7871bdf0fb5c876424b1eb09336a1c6f 249 Gene3D G3DSA:3.60.21.10 1 222 4.2E-19 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TSC_c06070 7871bdf0fb5c876424b1eb09336a1c6f 249 SUPERFAMILY SSF56300 1 212 6.49E-20 T 12-10-2018 TSC_c06070 7871bdf0fb5c876424b1eb09336a1c6f 249 Pfam PF00149 Calcineurin-like phosphoesterase 1 196 1.2E-9 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSC_c20290 f1bfca3ba3c97e459730de5be97f7bee 278 Pfam PF01556 DnaJ C terminal domain 118 256 5.2E-31 T 12-10-2018 IPR002939 Chaperone DnaJ, C-terminal TSC_c20290 f1bfca3ba3c97e459730de5be97f7bee 278 SUPERFAMILY SSF49493 183 267 5.36E-20 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TSC_c20290 f1bfca3ba3c97e459730de5be97f7bee 278 Gene3D G3DSA:2.60.260.20 179 278 1.9E-32 T 12-10-2018 TSC_c20290 f1bfca3ba3c97e459730de5be97f7bee 278 SUPERFAMILY SSF49493 110 191 1.44E-17 T 12-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 TSC_c20290 f1bfca3ba3c97e459730de5be97f7bee 278 Gene3D G3DSA:1.10.287.110 1 111 4.2E-48 T 12-10-2018 IPR036869 Chaperone J-domain superfamily TSC_c20290 f1bfca3ba3c97e459730de5be97f7bee 278 Pfam PF00226 DnaJ domain 3 64 9.6E-29 T 12-10-2018 IPR001623 DnaJ domain TSC_c20290 f1bfca3ba3c97e459730de5be97f7bee 278 Gene3D G3DSA:2.60.260.20 112 177 1.8E-26 T 12-10-2018 TSC_c20290 f1bfca3ba3c97e459730de5be97f7bee 278 ProSitePatterns PS00636 Nt-dnaJ domain signature. 44 63 - T 12-10-2018 IPR018253 DnaJ domain, conserved site TSC_c20290 f1bfca3ba3c97e459730de5be97f7bee 278 SUPERFAMILY SSF46565 1 104 1.7E-35 T 12-10-2018 IPR036869 Chaperone J-domain superfamily TSC_c20290 f1bfca3ba3c97e459730de5be97f7bee 278 SMART SM00271 2 59 1.2E-33 T 12-10-2018 IPR001623 DnaJ domain TSC_c20290 f1bfca3ba3c97e459730de5be97f7bee 278 PRINTS PR00625 DnaJ domain signature 59 78 1.1E-26 T 12-10-2018 IPR001623 DnaJ domain TSC_c20290 f1bfca3ba3c97e459730de5be97f7bee 278 PRINTS PR00625 DnaJ domain signature 5 23 1.1E-26 T 12-10-2018 IPR001623 DnaJ domain TSC_c20290 f1bfca3ba3c97e459730de5be97f7bee 278 PRINTS PR00625 DnaJ domain signature 23 38 1.1E-26 T 12-10-2018 IPR001623 DnaJ domain TSC_c20290 f1bfca3ba3c97e459730de5be97f7bee 278 PRINTS PR00625 DnaJ domain signature 39 59 1.1E-26 T 12-10-2018 IPR001623 DnaJ domain TSC_c21250 d55fbf5140e5801298194b1167900d07 434 SMART SM00387 320 421 1.8E-18 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c21250 d55fbf5140e5801298194b1167900d07 434 SUPERFAMILY SSF55874 280 422 2.88E-22 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c21250 d55fbf5140e5801298194b1167900d07 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 321 420 3.6E-12 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c21250 d55fbf5140e5801298194b1167900d07 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 401 3.4E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c21250 d55fbf5140e5801298194b1167900d07 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 369 3.4E-6 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c21250 d55fbf5140e5801298194b1167900d07 434 SMART SM00388 231 292 2.2E-15 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c21250 d55fbf5140e5801298194b1167900d07 434 Gene3D G3DSA:3.30.565.10 308 424 2.0E-21 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c21250 d55fbf5140e5801298194b1167900d07 434 SUPERFAMILY SSF47384 221 291 4.71E-15 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSC_c21250 d55fbf5140e5801298194b1167900d07 434 Pfam PF00512 His Kinase A (phospho-acceptor) domain 233 291 5.2E-14 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c21250 d55fbf5140e5801298194b1167900d07 434 Gene3D G3DSA:1.10.287.130 218 292 1.2E-16 T 12-10-2018 TSC_c10470 7f4cbbe09f6c91e5aa1fb966021eb038 318 ProSitePatterns PS00082 Extradiol ring-cleavage dioxygenases signature. 230 251 - T 12-10-2018 IPR000486 Extradiol ring-cleavage dioxygenase, class I /II GO:0003824|GO:0006725|GO:0008198|GO:0055114 TSC_c10470 7f4cbbe09f6c91e5aa1fb966021eb038 318 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 88 1.1E-6 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TSC_c10470 7f4cbbe09f6c91e5aa1fb966021eb038 318 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 135 252 2.7E-15 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TSC_c10470 7f4cbbe09f6c91e5aa1fb966021eb038 318 TIGRFAM TIGR02295 HpaD: 3,4-dihydroxyphenylacetate 2,3-dioxygenase 3 293 2.8E-131 T 12-10-2018 IPR011981 3,4-dihydroxyphenylacetate 2,3-dioxygenase, Mn/Fe-type TSC_c10470 7f4cbbe09f6c91e5aa1fb966021eb038 318 Gene3D G3DSA:3.10.180.10 135 294 3.1E-48 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c10470 7f4cbbe09f6c91e5aa1fb966021eb038 318 SUPERFAMILY SSF54593 1 259 4.76E-46 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c10470 7f4cbbe09f6c91e5aa1fb966021eb038 318 Gene3D G3DSA:3.10.180.10 1 132 2.2E-28 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c13260 7fdb0b39551ebe94bdac879d30e02ca0 345 SUPERFAMILY SSF53756 2 342 2.25E-55 T 12-10-2018 TSC_c13260 7fdb0b39551ebe94bdac879d30e02ca0 345 Pfam PF13439 Glycosyltransferase Family 4 92 161 8.9E-8 T 12-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 TSC_c13260 7fdb0b39551ebe94bdac879d30e02ca0 345 Pfam PF13692 Glycosyl transferases group 1 188 313 9.9E-20 T 12-10-2018 TSC_c13260 7fdb0b39551ebe94bdac879d30e02ca0 345 Gene3D G3DSA:3.40.50.2000 70 338 7.8E-42 T 12-10-2018 TSC_c13260 7fdb0b39551ebe94bdac879d30e02ca0 345 Gene3D G3DSA:3.40.50.2000 158 329 7.8E-42 T 12-10-2018 TSC_c15450 591d4e1f3ca639c03ce5577d26d89787 414 Gene3D G3DSA:1.10.287.130 164 278 2.4E-25 T 12-10-2018 TSC_c15450 591d4e1f3ca639c03ce5577d26d89787 414 PRINTS PR00344 Bacterial sensor protein C-terminal signature 344 358 6.1E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c15450 591d4e1f3ca639c03ce5577d26d89787 414 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 392 6.1E-9 T 12-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 TSC_c15450 591d4e1f3ca639c03ce5577d26d89787 414 SUPERFAMILY SSF158472 162 210 4.97E-8 T 12-10-2018 TSC_c15450 591d4e1f3ca639c03ce5577d26d89787 414 SMART SM00388 214 277 3.9E-11 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c15450 591d4e1f3ca639c03ce5577d26d89787 414 Pfam PF00672 HAMP domain 162 209 2.8E-11 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSC_c15450 591d4e1f3ca639c03ce5577d26d89787 414 SUPERFAMILY SSF47384 197 275 2.55E-13 T 12-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 TSC_c15450 591d4e1f3ca639c03ce5577d26d89787 414 SMART SM00304 160 213 1.5E-12 T 12-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 TSC_c15450 591d4e1f3ca639c03ce5577d26d89787 414 Pfam PF00512 His Kinase A (phospho-acceptor) domain 216 275 8.1E-12 T 12-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 TSC_c15450 591d4e1f3ca639c03ce5577d26d89787 414 SUPERFAMILY SSF55874 279 412 1.26E-26 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c15450 591d4e1f3ca639c03ce5577d26d89787 414 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 311 412 3.3E-16 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c15450 591d4e1f3ca639c03ce5577d26d89787 414 SMART SM00387 309 413 2.2E-21 T 12-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase TSC_c15450 591d4e1f3ca639c03ce5577d26d89787 414 Gene3D G3DSA:3.30.565.10 279 413 2.6E-25 T 12-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily TSC_c07520 e17728beb696bf7acb1417db63b41a5c 359 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 12 356 1.9E-111 T 12-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSC_c07520 e17728beb696bf7acb1417db63b41a5c 359 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 314 338 - T 12-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSC_c07520 e17728beb696bf7acb1417db63b41a5c 359 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 6 359 26.387 T 12-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSC_c07520 e17728beb696bf7acb1417db63b41a5c 359 Pfam PF01098 Cell cycle protein 39 356 7.9E-94 T 12-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 TSC_c02230 cd726e7767eac86bbffca95a032fd3dd 270 Pfam PF00436 Single-strand binding protein family 128 227 1.2E-22 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 TSC_c02230 cd726e7767eac86bbffca95a032fd3dd 270 Pfam PF00436 Single-strand binding protein family 5 105 7.6E-25 T 12-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 TSC_c02230 cd726e7767eac86bbffca95a032fd3dd 270 Hamap MF_00984 Single-stranded DNA-binding protein. 5 111 23.009 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TSC_c02230 cd726e7767eac86bbffca95a032fd3dd 270 Gene3D G3DSA:2.40.50.140 127 237 2.3E-36 T 12-10-2018 TSC_c02230 cd726e7767eac86bbffca95a032fd3dd 270 SUPERFAMILY SSF50249 3 121 1.03E-29 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c02230 cd726e7767eac86bbffca95a032fd3dd 270 SUPERFAMILY SSF50249 128 270 2.5E-28 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c02230 cd726e7767eac86bbffca95a032fd3dd 270 Hamap MF_00984 Single-stranded DNA-binding protein. 128 233 23.115 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TSC_c02230 cd726e7767eac86bbffca95a032fd3dd 270 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 112 1.1E-26 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TSC_c02230 cd726e7767eac86bbffca95a032fd3dd 270 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 127 226 2.5E-25 T 12-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 TSC_c02230 cd726e7767eac86bbffca95a032fd3dd 270 Gene3D G3DSA:2.40.50.140 1 126 2.2E-40 T 12-10-2018 TSC_c20100 aae61c428fd2fa80f42377f344216611 506 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 155 166 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site TSC_c20100 aae61c428fd2fa80f42377f344216611 506 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 450 460 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TSC_c20100 aae61c428fd2fa80f42377f344216611 506 Gene3D G3DSA:3.40.50.200 105 506 6.0E-75 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TSC_c20100 aae61c428fd2fa80f42377f344216611 506 PRINTS PR00723 Subtilisin serine protease family (S8) signature 221 234 5.8E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TSC_c20100 aae61c428fd2fa80f42377f344216611 506 PRINTS PR00723 Subtilisin serine protease family (S8) signature 449 465 5.8E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TSC_c20100 aae61c428fd2fa80f42377f344216611 506 PRINTS PR00723 Subtilisin serine protease family (S8) signature 150 169 5.8E-15 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TSC_c20100 aae61c428fd2fa80f42377f344216611 506 SUPERFAMILY SSF52743 129 505 7.07E-64 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TSC_c20100 aae61c428fd2fa80f42377f344216611 506 Pfam PF00082 Subtilase family 154 497 7.6E-47 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TSC_c20100 aae61c428fd2fa80f42377f344216611 506 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 225 235 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TSC_c20100 aae61c428fd2fa80f42377f344216611 506 Gene3D G3DSA:3.30.70.80 34 104 2.8E-6 T 12-10-2018 IPR037045 Peptidase S8 propeptide/proteinase inhibitor I9 superfamily Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 TSC_c08020 8129e67627375bb482d79e7f912bef20 286 SUPERFAMILY SSF103481 38 139 1.07E-17 T 12-10-2018 TSC_c08020 8129e67627375bb482d79e7f912bef20 286 Pfam PF00892 EamA-like transporter family 147 281 3.0E-27 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSC_c08020 8129e67627375bb482d79e7f912bef20 286 Pfam PF00892 EamA-like transporter family 6 136 7.8E-24 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSC_c08020 8129e67627375bb482d79e7f912bef20 286 SUPERFAMILY SSF103481 181 284 6.02E-19 T 12-10-2018 TSC_c19290 8381fbe50055be11f76ad003c82de56d 192 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 14 27 - T 12-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 TSC_c19290 8381fbe50055be11f76ad003c82de56d 192 Pfam PF01195 Peptidyl-tRNA hydrolase 3 171 4.5E-49 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TSC_c19290 8381fbe50055be11f76ad003c82de56d 192 Gene3D G3DSA:3.40.50.1470 1 183 1.3E-58 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 TSC_c19290 8381fbe50055be11f76ad003c82de56d 192 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 1 173 32.071 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TSC_c19290 8381fbe50055be11f76ad003c82de56d 192 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 2 171 1.4E-50 T 12-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 TSC_c19290 8381fbe50055be11f76ad003c82de56d 192 SUPERFAMILY SSF53178 1 180 1.57E-55 T 12-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 TSC_c05350 6e7705a88c65f009d882a7fcdacda530 373 Pfam PF06969 HemN C-terminal domain 288 351 5.6E-15 T 12-10-2018 IPR010723 HemN, C-terminal TSC_c05350 6e7705a88c65f009d882a7fcdacda530 373 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 3 326 1.2E-73 T 12-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 TSC_c05350 6e7705a88c65f009d882a7fcdacda530 373 SUPERFAMILY SSF102114 3 362 8.24E-84 T 12-10-2018 TSC_c05350 6e7705a88c65f009d882a7fcdacda530 373 Gene3D G3DSA:3.80.30.20 1 269 4.4E-79 T 12-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe TSC_c05350 6e7705a88c65f009d882a7fcdacda530 373 Pfam PF04055 Radical SAM superfamily 7 164 1.7E-23 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSC_c05350 6e7705a88c65f009d882a7fcdacda530 373 SMART SM00729 1 210 1.7E-46 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSC_c12420 781e1dc7604cbdbb300080550abaa34a 97 Gene3D G3DSA:3.30.460.10 7 96 4.3E-24 T 12-10-2018 TSC_c12420 781e1dc7604cbdbb300080550abaa34a 97 Pfam PF01909 Nucleotidyltransferase domain 14 92 6.1E-16 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSC_c12420 781e1dc7604cbdbb300080550abaa34a 97 SUPERFAMILY SSF81301 3 94 1.29E-24 T 12-10-2018 TSC_c07090 55499882bf796981a1d1eb15a8552efd 883 SUPERFAMILY SSF55073 27 189 9.58E-28 T 12-10-2018 IPR029787 Nucleotide cyclase TSC_c07090 55499882bf796981a1d1eb15a8552efd 883 Gene3D G3DSA:3.30.70.1230 26 201 1.4E-26 T 12-10-2018 IPR029787 Nucleotide cyclase TSC_c12120 75581c6d9ea9f8763c0da1986231e1d3 304 Gene3D G3DSA:1.10.443.10 113 303 6.6E-44 T 12-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 TSC_c12120 75581c6d9ea9f8763c0da1986231e1d3 304 SUPERFAMILY SSF56349 33 298 2.56E-45 T 12-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 TSC_c12120 75581c6d9ea9f8763c0da1986231e1d3 304 Gene3D G3DSA:1.10.150.130 19 107 4.9E-9 T 12-10-2018 IPR010998 Integrase/recombinase, N-terminal TSC_c12120 75581c6d9ea9f8763c0da1986231e1d3 304 Pfam PF00589 Phage integrase family 124 290 5.4E-33 T 12-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 TSC_c12120 75581c6d9ea9f8763c0da1986231e1d3 304 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 24 94 1.7E-7 T 12-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 TSC_c19210 3e4821f3bd93f2eb746fc9c10535e791 482 Gene3D G3DSA:3.20.20.70 155 457 8.7E-94 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c19210 3e4821f3bd93f2eb746fc9c10535e791 482 Pfam PF02065 Melibiase 159 307 5.5E-20 T 12-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 TSC_c19210 3e4821f3bd93f2eb746fc9c10535e791 482 SUPERFAMILY SSF51445 158 461 8.79E-76 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TSC_c19380 fee5a95bf9ebc22a1d3324056101d9a1 173 Pfam PF05685 Putative restriction endonuclease 9 166 2.8E-30 T 12-10-2018 IPR008538 Domain of unknown function DUF820 TSC_c19380 fee5a95bf9ebc22a1d3324056101d9a1 173 SUPERFAMILY SSF52980 6 151 2.09E-17 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSC_c19380 fee5a95bf9ebc22a1d3324056101d9a1 173 Gene3D G3DSA:3.90.1570.10 2 162 6.7E-14 T 12-10-2018 TSC_c09480 539922a4b6a0041968f1595024595e54 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 4.9E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09480 539922a4b6a0041968f1595024595e54 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 4.9E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09480 539922a4b6a0041968f1595024595e54 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 4.9E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09480 539922a4b6a0041968f1595024595e54 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 4.9E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09480 539922a4b6a0041968f1595024595e54 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 209 4.9E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09480 539922a4b6a0041968f1595024595e54 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 4.9E-29 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09480 539922a4b6a0041968f1595024595e54 230 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSC_c09480 539922a4b6a0041968f1595024595e54 230 SUPERFAMILY SSF51735 2 211 8.72E-63 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c09480 539922a4b6a0041968f1595024595e54 230 Pfam PF00106 short chain dehydrogenase 3 186 4.9E-54 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09480 539922a4b6a0041968f1595024595e54 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 3.9E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09480 539922a4b6a0041968f1595024595e54 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 3.9E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09480 539922a4b6a0041968f1595024595e54 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 3.9E-10 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c09480 539922a4b6a0041968f1595024595e54 230 Gene3D G3DSA:3.40.50.720 1 229 3.0E-69 T 12-10-2018 TSC_c19890 d5391df6b090d2e0ab55ea4aa0d4167b 390 SUPERFAMILY SSF103473 5 381 2.49E-29 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c19890 d5391df6b090d2e0ab55ea4aa0d4167b 390 Gene3D G3DSA:1.20.1250.20 7 198 2.2E-8 T 12-10-2018 TSC_c19890 d5391df6b090d2e0ab55ea4aa0d4167b 390 Pfam PF07690 Major Facilitator Superfamily 18 352 4.2E-19 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c19890 d5391df6b090d2e0ab55ea4aa0d4167b 390 Gene3D G3DSA:1.20.1250.20 210 389 6.9E-15 T 12-10-2018 TSC_c12240 3b4313b0d4eb4035c1c6d8b4f1bc5a48 133 SUPERFAMILY SSF88723 3 128 1.08E-18 T 12-10-2018 IPR029060 PIN-like domain superfamily TSC_c12240 3b4313b0d4eb4035c1c6d8b4f1bc5a48 133 Gene3D G3DSA:3.40.50.1010 1 130 3.4E-25 T 12-10-2018 TSC_c12240 3b4313b0d4eb4035c1c6d8b4f1bc5a48 133 Pfam PF01850 PIN domain 3 127 1.2E-7 T 12-10-2018 IPR002716 PIN domain TSC_c17840 ce8d4b0b752efa5310335a9b4d8e06d2 186 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 2 186 24.032 T 12-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid TSC_c17840 ce8d4b0b752efa5310335a9b4d8e06d2 186 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 127 182 2.6E-31 T 12-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal TSC_c17840 ce8d4b0b752efa5310335a9b4d8e06d2 186 Gene3D G3DSA:3.30.160.100 1 105 4.5E-38 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like TSC_c17840 ce8d4b0b752efa5310335a9b4d8e06d2 186 SUPERFAMILY SSF69754 5 104 8.11E-27 T 12-10-2018 IPR036567 Ribosome hibernation promotion factor-like TSC_c17840 ce8d4b0b752efa5310335a9b4d8e06d2 186 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 5 98 5.1E-24 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 TSC_c17840 ce8d4b0b752efa5310335a9b4d8e06d2 186 Gene3D G3DSA:3.30.505.50 140 186 2.6E-27 T 12-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily TSC_c17840 ce8d4b0b752efa5310335a9b4d8e06d2 186 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 5 98 1.6E-25 T 12-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 TSC_c01990 ecb5366f06e3146f78e0a9c75f97ecfe 344 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 180 196 - T 12-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TSC_c01990 ecb5366f06e3146f78e0a9c75f97ecfe 344 Gene3D G3DSA:1.10.1670.10 7 198 9.3E-74 T 12-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 TSC_c01990 ecb5366f06e3146f78e0a9c75f97ecfe 344 Pfam PF14815 NUDIX domain 220 316 3.4E-9 T 12-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 TSC_c01990 ecb5366f06e3146f78e0a9c75f97ecfe 344 Gene3D G3DSA:1.10.340.30 18 124 9.3E-74 T 12-10-2018 TSC_c01990 ecb5366f06e3146f78e0a9c75f97ecfe 344 SMART SM00525 179 199 3.0E-4 T 12-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 TSC_c01990 ecb5366f06e3146f78e0a9c75f97ecfe 344 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 32 159 1.4E-17 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSC_c01990 ecb5366f06e3146f78e0a9c75f97ecfe 344 SUPERFAMILY SSF48150 2 200 1.11E-66 T 12-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 TSC_c01990 ecb5366f06e3146f78e0a9c75f97ecfe 344 Pfam PF00633 Helix-hairpin-helix motif 96 119 2.0E-6 T 12-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 TSC_c01990 ecb5366f06e3146f78e0a9c75f97ecfe 344 SMART SM00478 36 178 2.6E-41 T 12-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 TSC_c08480 f9582df1ad3b79ea0d21e4e36df36550 623 Pfam PF16241 Domain of unknown function (DUF4900) 140 222 3.1E-26 T 12-10-2018 IPR032601 Protein of unknown function DUF4900 TSC_c21480 55d7e84c16fe9725fe6fd09b205cf085 173 Pfam PF00156 Phosphoribosyl transferase domain 35 159 2.9E-15 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSC_c21480 55d7e84c16fe9725fe6fd09b205cf085 173 Gene3D G3DSA:3.40.50.2020 1 170 1.3E-47 T 12-10-2018 TSC_c21480 55d7e84c16fe9725fe6fd09b205cf085 173 SUPERFAMILY SSF53271 10 158 2.23E-25 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TSC_c17390 2688561a81d01f99cef95bccedfcc90e 317 SUPERFAMILY SSF102588 52 307 2.22E-48 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TSC_c17390 2688561a81d01f99cef95bccedfcc90e 317 Gene3D G3DSA:3.40.50.10320 49 314 6.2E-56 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TSC_c17390 2688561a81d01f99cef95bccedfcc90e 317 Pfam PF02585 GlcNAc-PI de-N-acetylase 55 222 2.5E-28 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TSC_c07410 0a66d81d38fb3fafce5c5dac89ad0770 580 Gene3D G3DSA:1.20.1730.10 21 320 4.6E-38 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily TSC_c07410 0a66d81d38fb3fafce5c5dac89ad0770 580 Gene3D G3DSA:1.20.1730.10 340 564 3.2E-29 T 12-10-2018 IPR038377 Sodium/glucose symporter superfamily TSC_c07410 0a66d81d38fb3fafce5c5dac89ad0770 580 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 7 571 7.5E-250 T 12-10-2018 IPR019899 Sodium/solute symporter, VC2705 subfamily TSC_c07410 0a66d81d38fb3fafce5c5dac89ad0770 580 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 482 502 - T 12-10-2018 IPR018212 Sodium/solute symporter, conserved site TSC_c07410 0a66d81d38fb3fafce5c5dac89ad0770 580 Pfam PF00474 Sodium:solute symporter family 33 294 1.1E-36 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TSC_c07410 0a66d81d38fb3fafce5c5dac89ad0770 580 Pfam PF00474 Sodium:solute symporter family 385 500 7.2E-21 T 12-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 TSC_c24940 ed44b4c98e3249aa4e5ee236798bbd02 322 ProSitePatterns PS00433 Phosphofructokinase signature. 246 264 - T 12-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSC_c24940 ed44b4c98e3249aa4e5ee236798bbd02 322 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 303 9.6E-124 T 12-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 TSC_c24940 ed44b4c98e3249aa4e5ee236798bbd02 322 Gene3D G3DSA:3.40.50.460 140 254 1.2E-107 T 12-10-2018 TSC_c24940 ed44b4c98e3249aa4e5ee236798bbd02 322 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 321 47.532 T 12-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 TSC_c24940 ed44b4c98e3249aa4e5ee236798bbd02 322 Pfam PF00365 Phosphofructokinase 3 278 2.1E-106 T 12-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSC_c24940 ed44b4c98e3249aa4e5ee236798bbd02 322 SUPERFAMILY SSF53784 1 319 1.96E-115 T 12-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSC_c24940 ed44b4c98e3249aa4e5ee236798bbd02 322 Gene3D G3DSA:3.40.50.450 3 284 1.2E-107 T 12-10-2018 TSC_c24940 ed44b4c98e3249aa4e5ee236798bbd02 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 5.0E-83 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSC_c24940 ed44b4c98e3249aa4e5ee236798bbd02 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 5.0E-83 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSC_c24940 ed44b4c98e3249aa4e5ee236798bbd02 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 242 264 5.0E-83 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSC_c24940 ed44b4c98e3249aa4e5ee236798bbd02 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 213 225 5.0E-83 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSC_c24940 ed44b4c98e3249aa4e5ee236798bbd02 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 139 157 5.0E-83 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSC_c24940 ed44b4c98e3249aa4e5ee236798bbd02 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 159 175 5.0E-83 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSC_c24940 ed44b4c98e3249aa4e5ee236798bbd02 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 177 194 5.0E-83 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSC_c24940 ed44b4c98e3249aa4e5ee236798bbd02 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 5.0E-83 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSC_c24940 ed44b4c98e3249aa4e5ee236798bbd02 322 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 121 138 5.0E-83 T 12-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 TSC_c24940 ed44b4c98e3249aa4e5ee236798bbd02 322 PIRSF PIRSF000532 1 320 6.7E-119 T 12-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 TSC_c15590 99d3ee88c6b2606463b16e6f87359a40 1043 Pfam PF08264 Anticodon-binding domain of tRNA 677 827 9.9E-30 T 12-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 TSC_c15590 99d3ee88c6b2606463b16e6f87359a40 1043 Gene3D G3DSA:3.90.740.10 196 390 6.5E-268 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSC_c15590 99d3ee88c6b2606463b16e6f87359a40 1043 Gene3D G3DSA:3.40.50.620 14 617 6.5E-268 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c15590 99d3ee88c6b2606463b16e6f87359a40 1043 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 17 627 2.7E-183 T 12-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c15590 99d3ee88c6b2606463b16e6f87359a40 1043 Gene3D G3DSA:1.10.730.10 631 821 7.6E-62 T 12-10-2018 TSC_c15590 99d3ee88c6b2606463b16e6f87359a40 1043 SUPERFAMILY SSF47323 645 890 9.35E-55 T 12-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c15590 99d3ee88c6b2606463b16e6f87359a40 1043 SUPERFAMILY SSF52374 7 640 9.47E-143 T 12-10-2018 TSC_c15590 99d3ee88c6b2606463b16e6f87359a40 1043 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 384 399 1.7E-28 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSC_c15590 99d3ee88c6b2606463b16e6f87359a40 1043 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 510 523 1.7E-28 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSC_c15590 99d3ee88c6b2606463b16e6f87359a40 1043 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 40 51 1.7E-28 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSC_c15590 99d3ee88c6b2606463b16e6f87359a40 1043 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 550 559 1.7E-28 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSC_c15590 99d3ee88c6b2606463b16e6f87359a40 1043 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 225 248 1.7E-28 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSC_c15590 99d3ee88c6b2606463b16e6f87359a40 1043 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 3 1036 14.171 T 12-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSC_c15590 99d3ee88c6b2606463b16e6f87359a40 1043 SUPERFAMILY SSF50677 199 386 2.51E-47 T 12-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 TSC_c15590 99d3ee88c6b2606463b16e6f87359a40 1043 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 7 834 2.1E-292 T 12-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 TSC_c13440 d15a63af4bfcd35235fe7330a8baf329 421 Gene3D G3DSA:3.90.1150.10 286 421 2.1E-50 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c13440 d15a63af4bfcd35235fe7330a8baf329 421 SUPERFAMILY SSF53383 1 420 7.26E-121 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c13440 d15a63af4bfcd35235fe7330a8baf329 421 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 2 420 7.8E-190 T 12-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 TSC_c13440 d15a63af4bfcd35235fe7330a8baf329 421 PIRSF PIRSF001434 1 421 8.8E-119 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSC_c13440 d15a63af4bfcd35235fe7330a8baf329 421 Gene3D G3DSA:3.40.640.10 1 285 2.9E-98 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c13440 d15a63af4bfcd35235fe7330a8baf329 421 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 420 3.5E-126 T 12-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 TSC_c14250 68df941be5d0b41fef456c273f17257e 551 Pfam PF00361 Proton-conducting membrane transporter 152 355 4.7E-28 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c24060 1dd85e4153607064c1619708c9a35685 287 SUPERFAMILY SSF53850 35 234 2.0E-41 T 12-10-2018 TSC_c24060 1dd85e4153607064c1619708c9a35685 287 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 23 273 1.6E-61 T 12-10-2018 TSC_c24060 1dd85e4153607064c1619708c9a35685 287 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 15 244 1.5E-62 T 12-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 TSC_c24060 1dd85e4153607064c1619708c9a35685 287 Gene3D G3DSA:3.40.190.10 23 230 4.9E-60 T 12-10-2018 TSC_c24060 1dd85e4153607064c1619708c9a35685 287 Gene3D G3DSA:3.40.190.10 107 220 4.9E-60 T 12-10-2018 TSC_c09730 d02064e7018c6d7cd459b7e115746291 290 TIGRFAM TIGR01230 agmatinase: agmatinase 6 276 2.8E-63 T 12-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 TSC_c09730 d02064e7018c6d7cd459b7e115746291 290 PIRSF PIRSF036979 3 280 7.7E-59 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 TSC_c09730 d02064e7018c6d7cd459b7e115746291 290 Gene3D G3DSA:3.40.800.10 1 280 2.9E-73 T 12-10-2018 TSC_c09730 d02064e7018c6d7cd459b7e115746291 290 SUPERFAMILY SSF52768 9 278 5.04E-72 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily TSC_c09730 d02064e7018c6d7cd459b7e115746291 290 Pfam PF00491 Arginase family 16 275 7.1E-65 T 12-10-2018 IPR006035 Ureohydrolase GO:0046872 TSC_c17040 65024e04627b180229eda3e76d58fa28 261 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 257 24.793 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSC_c17040 65024e04627b180229eda3e76d58fa28 261 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 257 5.7E-76 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSC_c17040 65024e04627b180229eda3e76d58fa28 261 PIRSF PIRSF000193 1 260 4.6E-63 T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSC_c17040 65024e04627b180229eda3e76d58fa28 261 Gene3D G3DSA:1.10.3730.10 158 259 4.0E-33 T 12-10-2018 TSC_c17040 65024e04627b180229eda3e76d58fa28 261 SUPERFAMILY SSF48179 154 259 7.82E-30 T 12-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 TSC_c17040 65024e04627b180229eda3e76d58fa28 261 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 92 2.1E-14 T 12-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal TSC_c17040 65024e04627b180229eda3e76d58fa28 261 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 155 257 1.4E-34 T 12-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSC_c17040 65024e04627b180229eda3e76d58fa28 261 Gene3D G3DSA:3.40.50.720 1 157 1.9E-33 T 12-10-2018 TSC_c17040 65024e04627b180229eda3e76d58fa28 261 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 213 235 - T 12-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 TSC_c17040 65024e04627b180229eda3e76d58fa28 261 SUPERFAMILY SSF51735 1 153 9.87E-27 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c12860 b8c09d6859a7db09d3993b338a6c3b12 262 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 250 4.2E-15 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c12860 b8c09d6859a7db09d3993b338a6c3b12 262 Gene3D G3DSA:1.10.3720.10 5 260 1.1E-43 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c12860 b8c09d6859a7db09d3993b338a6c3b12 262 SUPERFAMILY SSF161098 5 258 1.83E-47 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c23550 f8e4778fa9da3b20d348fefc706ae5d7 66 Gene3D G3DSA:1.20.58.1350 1 66 2.6E-32 T 12-10-2018 IPR038405 Cytochrome oxidase Caa3-type, subunit IV superfamily TSC_c02290 d95cbede664161daf7eb6880f72f42c0 323 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 37 74 7.0E-10 T 12-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TSC_c02290 d95cbede664161daf7eb6880f72f42c0 323 PIRSF PIRSF005963 7 323 2.6E-143 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TSC_c02290 d95cbede664161daf7eb6880f72f42c0 323 SUPERFAMILY SSF102114 53 315 3.4E-61 T 12-10-2018 TSC_c02290 d95cbede664161daf7eb6880f72f42c0 323 Hamap MF_00206 Lipoyl synthase [lipA]. 39 323 139.757 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TSC_c02290 d95cbede664161daf7eb6880f72f42c0 323 Gene3D G3DSA:3.20.20.70 83 290 2.3E-19 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c02290 d95cbede664161daf7eb6880f72f42c0 323 Pfam PF04055 Radical SAM superfamily 91 253 9.4E-14 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSC_c02290 d95cbede664161daf7eb6880f72f42c0 323 TIGRFAM TIGR00510 lipA: lipoyl synthase 37 321 4.1E-119 T 12-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 TSC_c02290 d95cbede664161daf7eb6880f72f42c0 323 SMART SM00729 85 294 5.0E-13 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSC_c20980 af16f4e31b7d825cbfe6a3a382306266 188 SMART SM00382 26 188 5.8E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c20980 af16f4e31b7d825cbfe6a3a382306266 188 ProSitePatterns PS00211 ABC transporters family signature. 114 128 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c20980 af16f4e31b7d825cbfe6a3a382306266 188 Gene3D G3DSA:3.40.50.300 1 188 3.0E-49 T 12-10-2018 TSC_c20980 af16f4e31b7d825cbfe6a3a382306266 188 Pfam PF00005 ABC transporter 18 140 4.4E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c20980 af16f4e31b7d825cbfe6a3a382306266 188 SUPERFAMILY SSF52540 2 185 6.32E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c17350 19fa3341301666d5123e9054d3ef51c6 217 SMART SM00862 144 215 8.3E-25 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c17350 19fa3341301666d5123e9054d3ef51c6 217 Gene3D G3DSA:1.10.10.10 121 217 4.3E-27 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c17350 19fa3341301666d5123e9054d3ef51c6 217 SMART SM00448 1 111 2.6E-47 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c17350 19fa3341301666d5123e9054d3ef51c6 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 215 1.6E-22 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c17350 19fa3341301666d5123e9054d3ef51c6 217 Pfam PF00072 Response regulator receiver domain 4 112 1.8E-30 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c17350 19fa3341301666d5123e9054d3ef51c6 217 Gene3D G3DSA:3.40.50.2300 1 120 5.0E-42 T 12-10-2018 TSC_c17350 19fa3341301666d5123e9054d3ef51c6 217 SUPERFAMILY SSF52172 1 179 8.54E-46 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c16920 006c09061c41df1a6bc4a07e9f6b531c 66 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 14 58 4.2E-12 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 TSC_c16920 006c09061c41df1a6bc4a07e9f6b531c 66 Gene3D G3DSA:1.10.1660.10 10 61 2.2E-12 T 12-10-2018 TSC_c16920 006c09061c41df1a6bc4a07e9f6b531c 66 SUPERFAMILY SSF46955 12 60 1.59E-7 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TSC_c16920 006c09061c41df1a6bc4a07e9f6b531c 66 Pfam PF12728 Helix-turn-helix domain 11 59 5.8E-13 T 12-10-2018 TSC_c04130 61476e4dd074a06d86deaf690012f62f 394 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 392 1.6E-82 T 12-10-2018 IPR008135 Competence-induced protein CinA TSC_c04130 61476e4dd074a06d86deaf690012f62f 394 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 254 393 4.7E-28 T 12-10-2018 IPR008136 CinA, C-terminal TSC_c04130 61476e4dd074a06d86deaf690012f62f 394 SUPERFAMILY SSF53218 3 200 3.53E-32 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSC_c04130 61476e4dd074a06d86deaf690012f62f 394 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 394 127.121 T 12-10-2018 IPR008135 Competence-induced protein CinA TSC_c04130 61476e4dd074a06d86deaf690012f62f 394 Pfam PF02464 Competence-damaged protein 248 393 5.6E-44 T 12-10-2018 IPR008136 CinA, C-terminal TSC_c04130 61476e4dd074a06d86deaf690012f62f 394 SMART SM00852 5 172 5.1E-32 T 12-10-2018 IPR001453 MoaB/Mog domain TSC_c04130 61476e4dd074a06d86deaf690012f62f 394 Gene3D G3DSA:3.30.70.2860 174 247 2.6E-39 T 12-10-2018 TSC_c04130 61476e4dd074a06d86deaf690012f62f 394 Gene3D G3DSA:3.90.950.20 248 394 1.8E-55 T 12-10-2018 IPR036653 CinA-like, C-terminal TSC_c04130 61476e4dd074a06d86deaf690012f62f 394 Pfam PF00994 Probable molybdopterin binding domain 6 168 4.6E-29 T 12-10-2018 IPR001453 MoaB/Mog domain TSC_c04130 61476e4dd074a06d86deaf690012f62f 394 PIRSF PIRSF006728 1 394 1.2E-110 T 12-10-2018 IPR008135 Competence-induced protein CinA TSC_c04130 61476e4dd074a06d86deaf690012f62f 394 Gene3D G3DSA:3.40.980.10 1 172 1.5E-51 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSC_c04130 61476e4dd074a06d86deaf690012f62f 394 SUPERFAMILY SSF142433 241 393 2.62E-42 T 12-10-2018 IPR036653 CinA-like, C-terminal TSC_c14420 7512ce6054aceccbb4f2abbaab1b0ede 144 Pfam PF02381 MraZ protein, putative antitoxin-like 4 70 1.0E-17 T 12-10-2018 IPR020603 MraZ domain TSC_c14420 7512ce6054aceccbb4f2abbaab1b0ede 144 Pfam PF02381 MraZ protein, putative antitoxin-like 72 132 3.6E-12 T 12-10-2018 IPR020603 MraZ domain TSC_c14420 7512ce6054aceccbb4f2abbaab1b0ede 144 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 131 1.0E-34 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TSC_c14420 7512ce6054aceccbb4f2abbaab1b0ede 144 SUPERFAMILY SSF89447 1 132 3.14E-43 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily TSC_c14420 7512ce6054aceccbb4f2abbaab1b0ede 144 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 139 3.0E-71 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TSC_c14420 7512ce6054aceccbb4f2abbaab1b0ede 144 Gene3D G3DSA:2.40.330.20 1 138 6.0E-42 T 12-10-2018 IPR038619 MraZ superfamily TSC_c14420 7512ce6054aceccbb4f2abbaab1b0ede 144 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 144 45.525 T 12-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 TSC_c23390 5d2b78f03e878452574ba7e4da0524a6 439 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 252 430 2.1E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c23390 5d2b78f03e878452574ba7e4da0524a6 439 SUPERFAMILY SSF161098 198 438 3.53E-50 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c19240 c44730a0543c1e65e17dce440faccd3c 796 Gene3D G3DSA:2.60.40.4040 622 731 3.4E-17 T 12-10-2018 TSC_c19240 c44730a0543c1e65e17dce440faccd3c 796 SUPERFAMILY SSF51011 608 686 3.6E-13 T 12-10-2018 TSC_c19240 c44730a0543c1e65e17dce440faccd3c 796 Pfam PF01055 Glycosyl hydrolases family 31 250 691 3.6E-138 T 12-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 TSC_c19240 c44730a0543c1e65e17dce440faccd3c 796 Gene3D G3DSA:2.60.40.1760 59 249 1.4E-28 T 12-10-2018 TSC_c19240 c44730a0543c1e65e17dce440faccd3c 796 SUPERFAMILY SSF74650 58 255 4.71E-28 T 12-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 TSC_c19240 c44730a0543c1e65e17dce440faccd3c 796 ProSitePatterns PS00129 Glycosyl hydrolases family 31 active site. 419 426 - T 12-10-2018 IPR030458 Glycosyl hydrolases family 31, active site TSC_c19240 c44730a0543c1e65e17dce440faccd3c 796 Gene3D G3DSA:3.20.20.80 256 609 7.6E-133 T 12-10-2018 TSC_c19240 c44730a0543c1e65e17dce440faccd3c 796 Pfam PF13802 Galactose mutarotase-like 166 232 1.2E-15 T 12-10-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain TSC_c19240 c44730a0543c1e65e17dce440faccd3c 796 SUPERFAMILY SSF51445 258 606 1.79E-90 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TSC_c00470 3c68e6e7a5b19e3515440d3d71fb0d0a 211 Gene3D G3DSA:1.10.3720.10 1 211 1.8E-20 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c00470 3c68e6e7a5b19e3515440d3d71fb0d0a 211 SUPERFAMILY SSF161098 6 209 1.83E-23 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c02780 a929c0ba484b809b6d2a60d3e88a5145 72 Gene3D G3DSA:3.30.920.30 8 72 6.0E-8 T 12-10-2018 IPR038570 HicA superfamily TSC_c02780 a929c0ba484b809b6d2a60d3e88a5145 72 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 11 65 1.3E-6 T 12-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 TSC_c02780 a929c0ba484b809b6d2a60d3e88a5145 72 SUPERFAMILY SSF54786 6 71 3.33E-12 T 12-10-2018 TSC_c02020 d7f02687f525e67d5b54aad81cf7aa6a 292 SUPERFAMILY SSF54106 84 127 5.89E-12 T 12-10-2018 TSC_c02020 d7f02687f525e67d5b54aad81cf7aa6a 292 SUPERFAMILY SSF54001 173 287 6.13E-36 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TSC_c02020 d7f02687f525e67d5b54aad81cf7aa6a 292 Gene3D G3DSA:3.10.350.10 33 78 2.1E-22 T 12-10-2018 IPR036779 LysM domain superfamily TSC_c02020 d7f02687f525e67d5b54aad81cf7aa6a 292 Gene3D G3DSA:3.10.350.10 81 128 5.8E-19 T 12-10-2018 IPR036779 LysM domain superfamily TSC_c02020 d7f02687f525e67d5b54aad81cf7aa6a 292 Gene3D G3DSA:3.90.1720.10 167 291 2.3E-35 T 12-10-2018 TSC_c02020 d7f02687f525e67d5b54aad81cf7aa6a 292 SUPERFAMILY SSF54106 35 78 7.19E-13 T 12-10-2018 TSC_c02020 d7f02687f525e67d5b54aad81cf7aa6a 292 Pfam PF00877 NlpC/P60 family 182 285 8.9E-25 T 12-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain TSC_c02020 d7f02687f525e67d5b54aad81cf7aa6a 292 SMART SM00257 84 127 1.1E-16 T 12-10-2018 IPR018392 LysM domain TSC_c02020 d7f02687f525e67d5b54aad81cf7aa6a 292 SMART SM00257 35 78 7.0E-18 T 12-10-2018 IPR018392 LysM domain TSC_c02020 d7f02687f525e67d5b54aad81cf7aa6a 292 Pfam PF01476 LysM domain 36 78 2.5E-15 T 12-10-2018 IPR018392 LysM domain TSC_c02020 d7f02687f525e67d5b54aad81cf7aa6a 292 Pfam PF01476 LysM domain 85 127 1.3E-16 T 12-10-2018 IPR018392 LysM domain TSC_c20970 47eea3ba8f0465bf40aa9b9b2145d293 240 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 96 119 1.6E-11 T 12-10-2018 TSC_c20970 47eea3ba8f0465bf40aa9b9b2145d293 240 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 47 68 1.6E-11 T 12-10-2018 TSC_c20970 47eea3ba8f0465bf40aa9b9b2145d293 240 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 73 90 1.6E-11 T 12-10-2018 TSC_c20970 47eea3ba8f0465bf40aa9b9b2145d293 240 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 176 195 1.6E-11 T 12-10-2018 TSC_c20970 47eea3ba8f0465bf40aa9b9b2145d293 240 PIRSF PIRSF002764 18 238 2.7E-38 T 12-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria TSC_c20970 47eea3ba8f0465bf40aa9b9b2145d293 240 Pfam PF03379 CcmB protein 25 232 5.4E-35 T 12-10-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSC_c13540 ac8f38a39b0b282a6a18992e16280635 214 SUPERFAMILY SSF102114 115 179 5.89E-10 T 12-10-2018 TSC_c13540 ac8f38a39b0b282a6a18992e16280635 214 Gene3D G3DSA:3.20.20.70 112 203 1.2E-11 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c13540 ac8f38a39b0b282a6a18992e16280635 214 Pfam PF13353 4Fe-4S single cluster domain 123 203 1.0E-5 T 12-10-2018 TSC_c01680 967fcdd2164ea8f15bc357adba65e792 292 Gene3D G3DSA:3.20.20.220 1 292 3.7E-122 T 12-10-2018 TSC_c01680 967fcdd2164ea8f15bc357adba65e792 292 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 15 287 4.4E-99 T 12-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 TSC_c01680 967fcdd2164ea8f15bc357adba65e792 292 Pfam PF02219 Methylenetetrahydrofolate reductase 3 288 1.2E-94 T 12-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 TSC_c01680 967fcdd2164ea8f15bc357adba65e792 292 SUPERFAMILY SSF51730 1 289 1.69E-100 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like TSC_c24210 e7e9e34becd15dff7ec410e60061f93b 887 Gene3D G3DSA:1.20.5.340 146 248 9.7E-8 T 12-10-2018 TSC_c24210 e7e9e34becd15dff7ec410e60061f93b 887 Pfam PF00395 S-layer homology domain 19 61 1.2E-11 T 12-10-2018 IPR001119 S-layer homology domain TSC_c20160 a40af637a433cf1da5aa9c6daa752494 139 PRINTS PR00502 NUDIX hydrolase family signature 34 48 1.2E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSC_c20160 a40af637a433cf1da5aa9c6daa752494 139 PRINTS PR00502 NUDIX hydrolase family signature 48 63 1.2E-7 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSC_c20160 a40af637a433cf1da5aa9c6daa752494 139 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TSC_c20160 a40af637a433cf1da5aa9c6daa752494 139 Pfam PF00293 NUDIX domain 11 127 1.7E-22 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSC_c20160 a40af637a433cf1da5aa9c6daa752494 139 Gene3D G3DSA:3.90.79.10 1 137 6.9E-29 T 12-10-2018 TSC_c20160 a40af637a433cf1da5aa9c6daa752494 139 SUPERFAMILY SSF55811 5 133 6.5E-31 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSC_c03430 f3707ebc2c2ee07e0935608a49e4b700 211 Gene3D G3DSA:3.90.10.10 22 113 1.7E-9 T 12-10-2018 TSC_c03430 f3707ebc2c2ee07e0935608a49e4b700 211 Pfam PF14522 Cytochrome c7 and related cytochrome c 121 211 1.8E-8 T 12-10-2018 IPR029467 C-type polyheme cytochrome OmcB TSC_c03430 f3707ebc2c2ee07e0935608a49e4b700 211 SUPERFAMILY SSF48695 37 184 4.96E-43 T 12-10-2018 IPR036280 Multiheme cytochrome superfamily TSC_c10060 86718afa1c99797ee1a43abf18100ed4 203 Pfam PF04216 Protein involved in formate dehydrogenase formation 14 168 2.1E-14 T 12-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 TSC_c10060 86718afa1c99797ee1a43abf18100ed4 203 SUPERFAMILY SSF144020 17 183 4.05E-25 T 12-10-2018 IPR024064 FdhE-like superfamily TSC_c10060 86718afa1c99797ee1a43abf18100ed4 203 Gene3D G3DSA:3.90.1670.10 3 195 1.1E-24 T 12-10-2018 IPR024064 FdhE-like superfamily TSC_c08610 e5e66f72d11cb4e6b53fb247ebdb2167 384 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 69 214 3.7E-39 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TSC_c08610 e5e66f72d11cb4e6b53fb247ebdb2167 384 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 68 215 1.1E-39 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TSC_c08610 e5e66f72d11cb4e6b53fb247ebdb2167 384 Gene3D G3DSA:1.10.260.150 37 292 2.4E-62 T 12-10-2018 TSC_c03960 5eb5e4c280895eea77ae24d72c68a1f6 229 Pfam PF00005 ABC transporter 27 171 1.5E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c03960 5eb5e4c280895eea77ae24d72c68a1f6 229 Gene3D G3DSA:3.40.50.300 1 226 1.0E-66 T 12-10-2018 TSC_c03960 5eb5e4c280895eea77ae24d72c68a1f6 229 SUPERFAMILY SSF52540 4 223 1.69E-64 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c03960 5eb5e4c280895eea77ae24d72c68a1f6 229 SMART SM00382 32 218 9.6E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c03960 5eb5e4c280895eea77ae24d72c68a1f6 229 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c09280 f181054e3c23b870cf3ab96a24084bef 491 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 2 483 8.1E-179 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSC_c09280 f181054e3c23b870cf3ab96a24084bef 491 SUPERFAMILY SSF50249 1 137 4.0E-36 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c09280 f181054e3c23b870cf3ab96a24084bef 491 PRINTS PR00982 Lysyl-tRNA synthetase signature 181 191 3.3E-38 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSC_c09280 f181054e3c23b870cf3ab96a24084bef 491 PRINTS PR00982 Lysyl-tRNA synthetase signature 226 239 3.3E-38 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSC_c09280 f181054e3c23b870cf3ab96a24084bef 491 PRINTS PR00982 Lysyl-tRNA synthetase signature 244 261 3.3E-38 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSC_c09280 f181054e3c23b870cf3ab96a24084bef 491 PRINTS PR00982 Lysyl-tRNA synthetase signature 197 213 3.3E-38 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSC_c09280 f181054e3c23b870cf3ab96a24084bef 491 PRINTS PR00982 Lysyl-tRNA synthetase signature 365 381 3.3E-38 T 12-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSC_c09280 f181054e3c23b870cf3ab96a24084bef 491 Gene3D G3DSA:3.30.930.10 140 491 9.9E-132 T 12-10-2018 TSC_c09280 f181054e3c23b870cf3ab96a24084bef 491 Pfam PF00152 tRNA synthetases class II (D, K and N) 144 480 6.0E-84 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c09280 f181054e3c23b870cf3ab96a24084bef 491 SUPERFAMILY SSF55681 144 481 1.53E-114 T 12-10-2018 TSC_c09280 f181054e3c23b870cf3ab96a24084bef 491 Gene3D G3DSA:2.40.50.140 1 139 2.1E-39 T 12-10-2018 TSC_c09280 f181054e3c23b870cf3ab96a24084bef 491 Pfam PF01336 OB-fold nucleic acid binding domain 53 128 8.7E-17 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TSC_c09280 f181054e3c23b870cf3ab96a24084bef 491 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 7 483 42.369 T 12-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSC_c08600 bbb63c6b6eaae574ce18d55a90948b13 443 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 372 382 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TSC_c08600 bbb63c6b6eaae574ce18d55a90948b13 443 PRINTS PR00723 Subtilisin serine protease family (S8) signature 160 179 8.4E-10 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TSC_c08600 bbb63c6b6eaae574ce18d55a90948b13 443 PRINTS PR00723 Subtilisin serine protease family (S8) signature 371 387 8.4E-10 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TSC_c08600 bbb63c6b6eaae574ce18d55a90948b13 443 PRINTS PR00723 Subtilisin serine protease family (S8) signature 208 221 8.4E-10 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TSC_c08600 bbb63c6b6eaae574ce18d55a90948b13 443 Pfam PF00082 Subtilase family 164 427 1.4E-43 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TSC_c08600 bbb63c6b6eaae574ce18d55a90948b13 443 Gene3D G3DSA:3.40.50.200 98 440 2.1E-76 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TSC_c08600 bbb63c6b6eaae574ce18d55a90948b13 443 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 165 175 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site TSC_c08600 bbb63c6b6eaae574ce18d55a90948b13 443 SUPERFAMILY SSF52743 145 435 6.94E-70 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TSC_c12850 5aed769bf085c29668181b2157168ac6 477 Pfam PF00171 Aldehyde dehydrogenase family 15 472 3.6E-161 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSC_c12850 5aed769bf085c29668181b2157168ac6 477 Gene3D G3DSA:3.40.605.10 22 466 4.8E-175 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSC_c12850 5aed769bf085c29668181b2157168ac6 477 Gene3D G3DSA:3.40.309.10 251 441 4.8E-175 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSC_c12850 5aed769bf085c29668181b2157168ac6 477 SUPERFAMILY SSF53720 2 475 3.14E-155 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSC_c12850 5aed769bf085c29668181b2157168ac6 477 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TSC_c08280 f188516780ba921a9b6c0008b0fe76e4 157 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 68 152 4.3E-37 T 12-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 TSC_c08280 f188516780ba921a9b6c0008b0fe76e4 157 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 155 25.118 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TSC_c08280 f188516780ba921a9b6c0008b0fe76e4 157 SUPERFAMILY SSF55200 68 154 1.57E-31 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 TSC_c08280 f188516780ba921a9b6c0008b0fe76e4 157 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 1 154 4.0E-56 T 12-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TSC_c08280 f188516780ba921a9b6c0008b0fe76e4 157 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 1 61 9.1E-26 T 12-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TSC_c08280 f188516780ba921a9b6c0008b0fe76e4 157 Gene3D G3DSA:3.10.20.80 1 60 7.2E-27 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TSC_c08280 f188516780ba921a9b6c0008b0fe76e4 157 Gene3D G3DSA:3.30.110.10 61 155 8.3E-37 T 12-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 TSC_c08280 f188516780ba921a9b6c0008b0fe76e4 157 SUPERFAMILY SSF54364 1 63 1.18E-23 T 12-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 TSC_c08210 5ff1e5ac81421093323837710a8615fb 1661 SUPERFAMILY SSF52540 314 479 1.51E-9 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c08210 5ff1e5ac81421093323837710a8615fb 1661 Gene3D G3DSA:3.40.50.300 291 440 9.2E-7 T 12-10-2018 TSC_c08210 5ff1e5ac81421093323837710a8615fb 1661 SUPERFAMILY SSF48371 705 1480 8.96E-7 T 12-10-2018 IPR016024 Armadillo-type fold TSC_c09680 1dc2b1b26c78ee4a2883ae5748f6d3d2 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 129 141 3.2E-13 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c09680 1dc2b1b26c78ee4a2883ae5748f6d3d2 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 227 248 3.2E-13 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c09680 1dc2b1b26c78ee4a2883ae5748f6d3d2 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 298 319 3.2E-13 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c09680 1dc2b1b26c78ee4a2883ae5748f6d3d2 562 PRINTS PR01165 Cytochrome c oxidase subunit I signature 429 450 3.2E-13 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c09680 1dc2b1b26c78ee4a2883ae5748f6d3d2 562 SUPERFAMILY SSF81442 15 557 4.06E-119 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c09680 1dc2b1b26c78ee4a2883ae5748f6d3d2 562 Gene3D G3DSA:1.20.210.10 2 562 2.5E-166 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c09680 1dc2b1b26c78ee4a2883ae5748f6d3d2 562 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 229 283 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c09680 1dc2b1b26c78ee4a2883ae5748f6d3d2 562 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 20 463 5.1E-86 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c20230 333672daaa5a84523986af734fe8075f 225 Gene3D G3DSA:3.30.2170.10 2 224 4.5E-65 T 12-10-2018 TSC_c20230 333672daaa5a84523986af734fe8075f 225 Pfam PF04493 Endonuclease V 19 213 1.2E-60 T 12-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 TSC_c20230 333672daaa5a84523986af734fe8075f 225 Hamap MF_00801 Endonuclease V [nfi]. 9 223 32.68 T 12-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 TSC_c20300 ee32c5508313f2566f4df57d978641ac 78 Gene3D G3DSA:1.10.1660.10 6 78 1.3E-14 T 12-10-2018 TSC_c20300 ee32c5508313f2566f4df57d978641ac 78 SUPERFAMILY SSF46955 11 54 3.11E-5 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TSC_c20300 ee32c5508313f2566f4df57d978641ac 78 Pfam PF13591 MerR HTH family regulatory protein 14 77 2.8E-11 T 12-10-2018 TSC_c01870 2878b8607497102d360638f85be3ec1d 73 SUPERFAMILY SSF143100 2 61 1.96E-16 T 12-10-2018 IPR035069 TTHA1013/TTHA0281-like TSC_c01870 2878b8607497102d360638f85be3ec1d 73 Gene3D G3DSA:3.30.160.250 1 72 7.4E-16 T 12-10-2018 TSC_c12610 bb5f4d5a33ac2d6127d1dad7aa7c7e2b 102 SUPERFAMILY SSF88723 20 92 5.89E-6 T 12-10-2018 IPR029060 PIN-like domain superfamily TSC_c03920 5f9f9e83b031e5ab251b744a619a948e 250 Pfam PF00005 ABC transporter 19 170 6.7E-21 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c03920 5f9f9e83b031e5ab251b744a619a948e 250 SUPERFAMILY SSF52540 4 229 3.19E-46 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c03920 5f9f9e83b031e5ab251b744a619a948e 250 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c03920 5f9f9e83b031e5ab251b744a619a948e 250 Gene3D G3DSA:3.40.50.300 1 250 4.4E-65 T 12-10-2018 TSC_c03920 5f9f9e83b031e5ab251b744a619a948e 250 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 242 3.5E-100 T 12-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 TSC_c09200 464511c33c903c794bd87e9f3e13924c 194 Gene3D G3DSA:2.40.30.20 1 86 1.7E-23 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSC_c09200 464511c33c903c794bd87e9f3e13924c 194 Gene3D G3DSA:2.40.30.20 99 194 1.8E-34 T 12-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 TSC_c09200 464511c33c903c794bd87e9f3e13924c 194 SUPERFAMILY SSF63380 90 192 3.57E-34 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TSC_c09200 464511c33c903c794bd87e9f3e13924c 194 Pfam PF00677 Lumazine binding domain 3 84 1.1E-17 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSC_c09200 464511c33c903c794bd87e9f3e13924c 194 Pfam PF00677 Lumazine binding domain 97 181 1.5E-25 T 12-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSC_c09200 464511c33c903c794bd87e9f3e13924c 194 SUPERFAMILY SSF63380 1 90 8.33E-21 T 12-10-2018 IPR017938 Riboflavin synthase-like beta-barrel TSC_c09200 464511c33c903c794bd87e9f3e13924c 194 PIRSF PIRSF000498 1 194 1.4E-69 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSC_c09200 464511c33c903c794bd87e9f3e13924c 194 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 192 1.3E-60 T 12-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSC_c10280 1e054b01f11812f9c7ef78faff232798 113 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 109 1.3E-23 T 12-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 TSC_c10280 1e054b01f11812f9c7ef78faff232798 113 PIRSF PIRSF033490 1 112 8.1E-32 T 12-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 TSC_c10280 1e054b01f11812f9c7ef78faff232798 113 Gene3D G3DSA:2.30.30.110 1 113 7.4E-28 T 12-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor TSC_c10280 1e054b01f11812f9c7ef78faff232798 113 SUPERFAMILY SSF50118 3 112 5.23E-28 T 12-10-2018 TSC_c00150 61df69276299af79b6942bc353abfe7c 402 Pfam PF13347 MFS/sugar transport protein 45 334 1.6E-18 T 12-10-2018 TSC_c00150 61df69276299af79b6942bc353abfe7c 402 ProSitePatterns PS00216 Sugar transport proteins signature 1. 272 289 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TSC_c00150 61df69276299af79b6942bc353abfe7c 402 ProSitePatterns PS00216 Sugar transport proteins signature 1. 65 82 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TSC_c00150 61df69276299af79b6942bc353abfe7c 402 SUPERFAMILY SSF103473 11 400 3.27E-47 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c00150 61df69276299af79b6942bc353abfe7c 402 Gene3D G3DSA:1.20.1250.20 7 191 1.4E-22 T 12-10-2018 TSC_c00150 61df69276299af79b6942bc353abfe7c 402 Gene3D G3DSA:1.20.1250.20 202 402 6.8E-20 T 12-10-2018 TSC_c22070 79fd19c41286f60cf5bf7054ca52e61d 314 SUPERFAMILY SSF48576 10 312 1.26E-75 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TSC_c22070 79fd19c41286f60cf5bf7054ca52e61d 314 Pfam PF00348 Polyprenyl synthetase 33 256 5.4E-63 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TSC_c22070 79fd19c41286f60cf5bf7054ca52e61d 314 Gene3D G3DSA:1.10.600.10 3 312 1.7E-86 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TSC_c22070 79fd19c41286f60cf5bf7054ca52e61d 314 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 76 90 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site TSC_c22070 79fd19c41286f60cf5bf7054ca52e61d 314 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 198 210 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site TSC_c00650 19138a8b8705c374b7959db835bace84 156 PRINTS PR00502 NUDIX hydrolase family signature 26 40 1.8E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSC_c00650 19138a8b8705c374b7959db835bace84 156 PRINTS PR00502 NUDIX hydrolase family signature 40 55 1.8E-5 T 12-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 TSC_c00650 19138a8b8705c374b7959db835bace84 156 ProSitePatterns PS00893 Nudix box signature. 31 52 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TSC_c00650 19138a8b8705c374b7959db835bace84 156 Gene3D G3DSA:3.90.79.10 1 144 1.9E-41 T 12-10-2018 TSC_c00650 19138a8b8705c374b7959db835bace84 156 SUPERFAMILY SSF55811 4 141 7.08E-29 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSC_c00650 19138a8b8705c374b7959db835bace84 156 Pfam PF00293 NUDIX domain 2 107 6.2E-14 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSC_c11900 42fb837dd4c55f7c2d55e7f661b1182b 380 Gene3D G3DSA:1.10.540.10 3 114 1.3E-35 T 12-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 TSC_c11900 42fb837dd4c55f7c2d55e7f661b1182b 380 Gene3D G3DSA:1.20.140.10 229 378 2.2E-56 T 12-10-2018 TSC_c11900 42fb837dd4c55f7c2d55e7f661b1182b 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 117 211 2.9E-22 T 12-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 TSC_c11900 42fb837dd4c55f7c2d55e7f661b1182b 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 330 349 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSC_c11900 42fb837dd4c55f7c2d55e7f661b1182b 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 119 131 - T 12-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 TSC_c11900 42fb837dd4c55f7c2d55e7f661b1182b 380 Gene3D G3DSA:2.40.110.10 116 228 2.2E-40 T 12-10-2018 TSC_c11900 42fb837dd4c55f7c2d55e7f661b1182b 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 4 113 1.5E-32 T 12-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 TSC_c11900 42fb837dd4c55f7c2d55e7f661b1182b 380 SUPERFAMILY SSF56645 4 236 7.59E-78 T 12-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 TSC_c11900 42fb837dd4c55f7c2d55e7f661b1182b 380 PIRSF PIRSF016578 1 77 0.0016 T 12-10-2018 TSC_c11900 42fb837dd4c55f7c2d55e7f661b1182b 380 PIRSF PIRSF016578 125 377 9.1E-12 T 12-10-2018 TSC_c11900 42fb837dd4c55f7c2d55e7f661b1182b 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 223 371 1.9E-51 T 12-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 TSC_c11900 42fb837dd4c55f7c2d55e7f661b1182b 380 SUPERFAMILY SSF47203 221 373 5.32E-59 T 12-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 TSC_c19330 4da1ed5ab42615983f9a5d90a9273158 155 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 152 36.852 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TSC_c19330 4da1ed5ab42615983f9a5d90a9273158 155 SUPERFAMILY SSF63411 4 148 9.16E-56 T 12-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 TSC_c19330 4da1ed5ab42615983f9a5d90a9273158 155 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 9 140 1.0E-62 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TSC_c19330 4da1ed5ab42615983f9a5d90a9273158 155 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 3 146 1.1E-52 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TSC_c19330 4da1ed5ab42615983f9a5d90a9273158 155 Gene3D G3DSA:3.30.1360.80 1 155 8.5E-57 T 12-10-2018 IPR037005 S-ribosylhomocysteinase (LuxS) superfamily GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TSC_c19330 4da1ed5ab42615983f9a5d90a9273158 155 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 8.7E-32 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TSC_c19330 4da1ed5ab42615983f9a5d90a9273158 155 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 48 66 8.7E-32 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TSC_c19330 4da1ed5ab42615983f9a5d90a9273158 155 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 114 133 8.7E-32 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TSC_c19330 4da1ed5ab42615983f9a5d90a9273158 155 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 72 90 8.7E-32 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TSC_c19330 4da1ed5ab42615983f9a5d90a9273158 155 PIRSF PIRSF006160 1 154 1.4E-59 T 12-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TSC_c01050 09d6e666cd7c95af9b0519b275b8abd8 340 Gene3D G3DSA:3.40.50.300 9 320 2.6E-84 T 12-10-2018 TSC_c01050 09d6e666cd7c95af9b0519b275b8abd8 340 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 340 67.54 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 TSC_c01050 09d6e666cd7c95af9b0519b275b8abd8 340 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 8 314 1.1E-63 T 12-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 TSC_c01050 09d6e666cd7c95af9b0519b275b8abd8 340 Gene3D G3DSA:1.20.1050.90 116 288 2.6E-84 T 12-10-2018 TSC_c01050 09d6e666cd7c95af9b0519b275b8abd8 340 SUPERFAMILY SSF52540 1 314 1.07E-34 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c23860 1f4c71c01edaeda676efc800009a441e 249 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 104 220 1.5E-10 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c23860 1f4c71c01edaeda676efc800009a441e 249 Gene3D G3DSA:1.20.120.1600 15 117 1.9E-42 T 12-10-2018 TSC_c23860 1f4c71c01edaeda676efc800009a441e 249 Gene3D G3DSA:3.40.50.1000 5 240 1.9E-42 T 12-10-2018 IPR023214 HAD superfamily TSC_c23860 1f4c71c01edaeda676efc800009a441e 249 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 118 214 2.8E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c23860 1f4c71c01edaeda676efc800009a441e 249 SUPERFAMILY SSF56784 1 248 1.06E-42 T 12-10-2018 IPR036412 HAD-like superfamily TSC_c23860 1f4c71c01edaeda676efc800009a441e 249 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 220 1.4E-17 T 12-10-2018 TSC_c01140 77df9eeb05fa145b98b5744260164ce9 294 Pfam PF07136 Protein of unknown function (DUF1385) 59 288 4.1E-72 T 12-10-2018 IPR010787 Protein of unknown function DUF1385 TSC_c01140 77df9eeb05fa145b98b5744260164ce9 294 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 59 289 3.0E-112 T 12-10-2018 IPR010787 Protein of unknown function DUF1385 TSC_c23250 4c2dd74fd40cf67f282ad89f9fac0a32 371 Pfam PF00557 Metallopeptidase family M24 144 354 3.3E-35 T 12-10-2018 IPR000994 Peptidase M24 TSC_c23250 4c2dd74fd40cf67f282ad89f9fac0a32 371 Gene3D G3DSA:3.90.230.10 137 368 1.5E-42 T 12-10-2018 TSC_c23250 4c2dd74fd40cf67f282ad89f9fac0a32 371 SUPERFAMILY SSF55920 136 365 4.84E-39 T 12-10-2018 IPR036005 Creatinase/aminopeptidase-like TSC_c21810 40d5c3e166d5e2f70c6a9bdbbf53cad4 227 SMART SM01211 1 225 4.4E-134 T 12-10-2018 TSC_c21810 40d5c3e166d5e2f70c6a9bdbbf53cad4 227 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 224 4.4E-97 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSC_c21810 40d5c3e166d5e2f70c6a9bdbbf53cad4 227 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 208 4.5E-47 T 12-10-2018 TSC_c21810 40d5c3e166d5e2f70c6a9bdbbf53cad4 227 SUPERFAMILY SSF52317 1 223 1.75E-76 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c21810 40d5c3e166d5e2f70c6a9bdbbf53cad4 227 Gene3D G3DSA:3.40.50.880 1 226 1.5E-71 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c21810 40d5c3e166d5e2f70c6a9bdbbf53cad4 227 PIRSF PIRSF001586 1 227 1.8E-87 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSC_c21810 40d5c3e166d5e2f70c6a9bdbbf53cad4 227 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 223 45.607 T 12-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSC_c07530 a666bd529da63402a6b5554192b9248a 368 SMART SM00382 43 226 3.1E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c07530 a666bd529da63402a6b5554192b9248a 368 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c07530 a666bd529da63402a6b5554192b9248a 368 Pfam PF08402 TOBE domain 283 365 3.7E-10 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSC_c07530 a666bd529da63402a6b5554192b9248a 368 Gene3D G3DSA:2.40.50.940 237 289 1.0E-7 T 12-10-2018 TSC_c07530 a666bd529da63402a6b5554192b9248a 368 Gene3D G3DSA:2.40.50.140 290 333 1.0E-7 T 12-10-2018 TSC_c07530 a666bd529da63402a6b5554192b9248a 368 SUPERFAMILY SSF52540 19 256 2.26E-87 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c07530 a666bd529da63402a6b5554192b9248a 368 Gene3D G3DSA:3.40.50.300 20 236 4.2E-64 T 12-10-2018 TSC_c07530 a666bd529da63402a6b5554192b9248a 368 Pfam PF00005 ABC transporter 34 176 3.5E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c07530 a666bd529da63402a6b5554192b9248a 368 SUPERFAMILY SSF50331 252 365 4.76E-14 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSC_c18520 415999cebe378e515b2961b0b4e89696 425 Gene3D G3DSA:3.40.718.10 1 425 2.8E-177 T 12-10-2018 TSC_c18520 415999cebe378e515b2961b0b4e89696 425 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 306 325 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 TSC_c18520 415999cebe378e515b2961b0b4e89696 425 SUPERFAMILY SSF53659 3 425 9.41E-142 T 12-10-2018 TSC_c18520 415999cebe378e515b2961b0b4e89696 425 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 3 425 2.6E-212 T 12-10-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 TSC_c18520 415999cebe378e515b2961b0b4e89696 425 SMART SM01329 29 421 1.3E-175 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TSC_c18520 415999cebe378e515b2961b0b4e89696 425 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 30 420 7.4E-114 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TSC_c16270 dc73d6cd41b09ff11eb094bd330ef907 151 Gene3D G3DSA:1.10.530.10 20 148 1.4E-27 T 12-10-2018 TSC_c16270 dc73d6cd41b09ff11eb094bd330ef907 151 SUPERFAMILY SSF53955 21 148 6.62E-32 T 12-10-2018 IPR023346 Lysozyme-like domain superfamily TSC_c16270 dc73d6cd41b09ff11eb094bd330ef907 151 Pfam PF01464 Transglycosylase SLT domain 31 124 6.4E-17 T 12-10-2018 IPR008258 Transglycosylase SLT domain 1 TSC_c18320 4d537f0681cfd256452abc1716b7c418 426 Hamap MF_00220_B Dihydroorotase [pyrC]. 2 424 42.64 T 12-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c18320 4d537f0681cfd256452abc1716b7c418 426 SUPERFAMILY SSF51556 50 367 1.12E-94 T 12-10-2018 IPR032466 Metal-dependent hydrolase TSC_c18320 4d537f0681cfd256452abc1716b7c418 426 ProSitePatterns PS00483 Dihydroorotase signature 2. 304 315 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c18320 4d537f0681cfd256452abc1716b7c418 426 Pfam PF01979 Amidohydrolase family 47 421 8.7E-21 T 12-10-2018 IPR006680 Amidohydrolase-related GO:0016787 TSC_c18320 4d537f0681cfd256452abc1716b7c418 426 ProSitePatterns PS00482 Dihydroorotase signature 1. 53 61 - T 12-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c18320 4d537f0681cfd256452abc1716b7c418 426 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 17 423 3.0E-116 T 12-10-2018 TSC_c18320 4d537f0681cfd256452abc1716b7c418 426 Gene3D G3DSA:2.30.40.10 366 426 1.4E-20 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSC_c18320 4d537f0681cfd256452abc1716b7c418 426 Gene3D G3DSA:2.30.40.10 1 53 2.7E-9 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSC_c18320 4d537f0681cfd256452abc1716b7c418 426 Gene3D G3DSA:3.20.20.140 54 365 3.6E-127 T 12-10-2018 TSC_c18320 4d537f0681cfd256452abc1716b7c418 426 SUPERFAMILY SSF51338 2 423 9.64E-19 T 12-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 TSC_c04820 e28488b55d0857058089985484a67385 69 Pfam PF08672 Anaphase promoting complex (APC) subunit 2 24 53 1.0E-4 T 12-10-2018 IPR014786 Anaphase-promoting complex subunit 2, C-terminal Reactome: R-HSA-141430|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-176407|Reactome: R-HSA-176408|Reactome: R-HSA-176409|Reactome: R-HSA-176412|Reactome: R-HSA-179409|Reactome: R-HSA-2467813|Reactome: R-HSA-2559582|Reactome: R-HSA-69017|Reactome: R-HSA-983168 TSC_c05410 3d4c2ef0c7d0e0eda9b47a3b30b1ae9c 428 SUPERFAMILY SSF46548 18 98 7.32E-19 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSC_c05410 3d4c2ef0c7d0e0eda9b47a3b30b1ae9c 428 Pfam PF02754 Cysteine-rich domain 309 393 1.6E-17 T 12-10-2018 IPR004017 Cysteine-rich domain TSC_c05410 3d4c2ef0c7d0e0eda9b47a3b30b1ae9c 428 Pfam PF02754 Cysteine-rich domain 183 260 3.5E-13 T 12-10-2018 IPR004017 Cysteine-rich domain TSC_c05410 3d4c2ef0c7d0e0eda9b47a3b30b1ae9c 428 Pfam PF13183 4Fe-4S dicluster domain 21 88 1.2E-11 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c05410 3d4c2ef0c7d0e0eda9b47a3b30b1ae9c 428 PIRSF PIRSF000139 6 420 6.1E-128 T 12-10-2018 TSC_c05410 3d4c2ef0c7d0e0eda9b47a3b30b1ae9c 428 Gene3D G3DSA:1.10.1060.10 12 101 3.7E-8 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSC_c05410 3d4c2ef0c7d0e0eda9b47a3b30b1ae9c 428 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c17570 0c95b48ae2137fb22c3e2e9ba80e515a 375 Gene3D G3DSA:3.20.20.70 8 321 5.1E-41 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c17570 0c95b48ae2137fb22c3e2e9ba80e515a 375 TIGRFAM TIGR04053 sam_11: radical SAM protein, BA_1875 family 6 361 4.1E-141 T 12-10-2018 IPR027634 Radical SAM protein, BA_1875 family TSC_c17570 0c95b48ae2137fb22c3e2e9ba80e515a 375 Pfam PF13186 Iron-sulfur cluster-binding domain 277 330 7.7E-5 T 12-10-2018 IPR023885 4Fe4S-binding SPASM domain TSC_c17570 0c95b48ae2137fb22c3e2e9ba80e515a 375 Pfam PF04055 Radical SAM superfamily 16 172 1.4E-19 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSC_c17570 0c95b48ae2137fb22c3e2e9ba80e515a 375 SUPERFAMILY SSF102114 5 338 3.66E-65 T 12-10-2018 TSC_c17570 0c95b48ae2137fb22c3e2e9ba80e515a 375 PIRSF PIRSF037420 2 367 7.1E-89 T 12-10-2018 IPR017200 Coenzyme PQQ synthesis protein E TSC_c17570 0c95b48ae2137fb22c3e2e9ba80e515a 375 SMART SM00729 11 214 3.6E-4 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSC_c16730 a260586c247fe822ffb80bb88dd975b0 493 Gene3D G3DSA:3.40.605.10 22 486 4.3E-187 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSC_c16730 a260586c247fe822ffb80bb88dd975b0 493 SUPERFAMILY SSF53720 13 491 1.44E-175 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSC_c16730 a260586c247fe822ffb80bb88dd975b0 493 Pfam PF00171 Aldehyde dehydrogenase family 28 488 6.2E-178 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSC_c16730 a260586c247fe822ffb80bb88dd975b0 493 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 263 270 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TSC_c16730 a260586c247fe822ffb80bb88dd975b0 493 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 291 302 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TSC_c16730 a260586c247fe822ffb80bb88dd975b0 493 Gene3D G3DSA:3.40.309.10 268 458 4.3E-187 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSC_c04280 fdc7af509dfb5ff83f0c23850f7c99fe 344 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 17 326 2.8E-95 T 12-10-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030975 TSC_c04280 fdc7af509dfb5ff83f0c23850f7c99fe 344 SUPERFAMILY SSF53850 17 332 2.92E-61 T 12-10-2018 TSC_c04280 fdc7af509dfb5ff83f0c23850f7c99fe 344 Gene3D G3DSA:3.40.190.10 118 327 3.2E-103 T 12-10-2018 TSC_c04280 fdc7af509dfb5ff83f0c23850f7c99fe 344 Pfam PF13343 Bacterial extracellular solute-binding protein 67 289 3.2E-30 T 12-10-2018 TSC_c04280 fdc7af509dfb5ff83f0c23850f7c99fe 344 Gene3D G3DSA:3.40.190.10 20 302 3.2E-103 T 12-10-2018 TSC_c22860 e27c3434f7e197596d3985e9b52676b9 313 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 239 250 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c22860 e27c3434f7e197596d3985e9b52676b9 313 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 272 283 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c22860 e27c3434f7e197596d3985e9b52676b9 313 Gene3D G3DSA:3.30.70.20 28 77 3.8E-10 T 12-10-2018 TSC_c22860 e27c3434f7e197596d3985e9b52676b9 313 SUPERFAMILY SSF54862 17 290 4.25E-22 T 12-10-2018 TSC_c22860 e27c3434f7e197596d3985e9b52676b9 313 Pfam PF13237 4Fe-4S dicluster domain 236 283 1.2E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c22860 e27c3434f7e197596d3985e9b52676b9 313 Pfam PF13187 4Fe-4S dicluster domain 35 74 2.8E-6 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c22860 e27c3434f7e197596d3985e9b52676b9 313 Gene3D G3DSA:3.30.70.20 233 306 4.8E-12 T 12-10-2018 TSC_c22860 e27c3434f7e197596d3985e9b52676b9 313 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 62 73 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c21710 9de16b40bb9fd1dacc2caef3008c88f3 212 Pfam PF02602 Uroporphyrinogen-III synthase HemD 3 205 2.5E-40 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSC_c21710 9de16b40bb9fd1dacc2caef3008c88f3 212 Gene3D G3DSA:3.40.50.10090 137 211 6.5E-6 T 12-10-2018 TSC_c21710 9de16b40bb9fd1dacc2caef3008c88f3 212 Gene3D G3DSA:3.40.50.10090 25 136 1.0E-21 T 12-10-2018 TSC_c21710 9de16b40bb9fd1dacc2caef3008c88f3 212 SUPERFAMILY SSF69618 2 211 1.44E-40 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSC_c11270 b30b61741860ad222d37b5c6f9d41d46 109 Pfam PF07843 Protein of unknown function (DUF1634) 9 105 1.6E-21 T 12-10-2018 IPR012861 Protein of unknown function DUF1634 TSC_c07070 d7e2ae6101ef85194e376454802af193 327 PIRSF PIRSF000102 1 326 5.3E-72 T 12-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 TSC_c07070 d7e2ae6101ef85194e376454802af193 327 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 155 167 - T 12-10-2018 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 TSC_c07070 d7e2ae6101ef85194e376454802af193 327 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 5 152 4.5E-38 T 12-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 TSC_c07070 d7e2ae6101ef85194e376454802af193 327 Hamap MF_01517 Malate dehydrogenase [mdh]. 1 325 57.013 T 12-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 TSC_c07070 d7e2ae6101ef85194e376454802af193 327 Gene3D G3DSA:3.40.50.720 1 154 4.3E-59 T 12-10-2018 TSC_c07070 d7e2ae6101ef85194e376454802af193 327 SUPERFAMILY SSF51735 1 155 4.93E-46 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c07070 d7e2ae6101ef85194e376454802af193 327 SUPERFAMILY SSF56327 156 323 3.55E-62 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TSC_c07070 d7e2ae6101ef85194e376454802af193 327 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 3 321 8.7E-156 T 12-10-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 TSC_c07070 d7e2ae6101ef85194e376454802af193 327 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 156 323 1.4E-38 T 12-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 TSC_c07070 d7e2ae6101ef85194e376454802af193 327 Gene3D G3DSA:3.90.110.10 155 325 1.4E-65 T 12-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 TSC_c19120 206575416deae86fb4448157aa1223e8 607 SMART SM00382 378 566 1.8E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c19120 206575416deae86fb4448157aa1223e8 607 SUPERFAMILY SSF90123 27 336 2.62E-21 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSC_c19120 206575416deae86fb4448157aa1223e8 607 Gene3D G3DSA:3.40.50.300 340 592 1.0E-80 T 12-10-2018 TSC_c19120 206575416deae86fb4448157aa1223e8 607 Pfam PF00005 ABC transporter 369 520 1.2E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c19120 206575416deae86fb4448157aa1223e8 607 Gene3D G3DSA:1.20.1560.10 1 339 1.7E-10 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSC_c19120 206575416deae86fb4448157aa1223e8 607 ProSitePatterns PS00211 ABC transporters family signature. 492 506 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c19120 206575416deae86fb4448157aa1223e8 607 SUPERFAMILY SSF52540 350 590 2.5E-71 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c21870 8afa0e8ad9d4bc2d30807dc5d8388c29 534 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 482 1.4E-14 T 12-10-2018 IPR003395 RecF/RecN/SMC, N-terminal TSC_c21870 8afa0e8ad9d4bc2d30807dc5d8388c29 534 Gene3D G3DSA:3.40.50.300 244 521 3.4E-58 T 12-10-2018 TSC_c21870 8afa0e8ad9d4bc2d30807dc5d8388c29 534 SUPERFAMILY SSF52540 1 487 1.43E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c21870 8afa0e8ad9d4bc2d30807dc5d8388c29 534 SMART SM00382 21 482 0.0019 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c21870 8afa0e8ad9d4bc2d30807dc5d8388c29 534 PIRSF PIRSF003128 1 524 1.5E-135 T 12-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 TSC_c21870 8afa0e8ad9d4bc2d30807dc5d8388c29 534 Gene3D G3DSA:3.40.50.300 1 227 2.8E-30 T 12-10-2018 TSC_c21020 3654fbab1645675e9da4455910b914fc 429 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 28 8.0E-4 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TSC_c21020 3654fbab1645675e9da4455910b914fc 429 Gene3D G3DSA:3.50.50.60 46 348 1.1E-85 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c21020 3654fbab1645675e9da4455910b914fc 429 Pfam PF09242 Flavocytochrome c sulphide dehydrogenase, flavin-binding 368 426 2.5E-11 T 12-10-2018 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 TSC_c21020 3654fbab1645675e9da4455910b914fc 429 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 3 26 4.2E-6 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TSC_c21020 3654fbab1645675e9da4455910b914fc 429 SUPERFAMILY SSF51905 172 288 1.54E-27 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c21020 3654fbab1645675e9da4455910b914fc 429 SUPERFAMILY SSF51905 44 163 3.26E-24 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c21020 3654fbab1645675e9da4455910b914fc 429 Gene3D G3DSA:3.50.50.60 158 288 1.1E-85 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c21020 3654fbab1645675e9da4455910b914fc 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 46 68 2.2E-5 T 12-10-2018 TSC_c21020 3654fbab1645675e9da4455910b914fc 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 320 327 2.2E-5 T 12-10-2018 TSC_c21020 3654fbab1645675e9da4455910b914fc 429 SUPERFAMILY SSF55424 367 427 1.9E-10 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSC_c21020 3654fbab1645675e9da4455910b914fc 429 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 46 161 1.4E-12 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSC_c03320 eb3becb115fda1b1f37bfb0cd6640e0d 353 Gene3D G3DSA:3.40.640.10 12 252 5.7E-128 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c03320 eb3becb115fda1b1f37bfb0cd6640e0d 353 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 177 197 - T 12-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site TSC_c03320 eb3becb115fda1b1f37bfb0cd6640e0d 353 SUPERFAMILY SSF53383 2 350 4.96E-90 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c03320 eb3becb115fda1b1f37bfb0cd6640e0d 353 Pfam PF00266 Aminotransferase class-V 26 316 2.4E-30 T 12-10-2018 IPR000192 Aminotransferase class V domain TSC_c03320 eb3becb115fda1b1f37bfb0cd6640e0d 353 Gene3D G3DSA:3.90.1150.10 3 334 5.7E-128 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c03320 eb3becb115fda1b1f37bfb0cd6640e0d 353 PIRSF PIRSF000524 1 353 6.0E-97 T 12-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 TSC_c00060 a57c0005834ce6ae6d204e15239c81e4 489 Pfam PF09992 Phosphodiester glycosidase 377 486 5.9E-17 T 12-10-2018 IPR018711 Phosphodiester glycosidase TSC_c13610 9062ecd14e028481b4f7c780e47d2a3b 389 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 6 389 40.485 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13610 9062ecd14e028481b4f7c780e47d2a3b 389 PRINTS PR00477 Phosphoglycerate kinase family signature 187 206 1.4E-84 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13610 9062ecd14e028481b4f7c780e47d2a3b 389 PRINTS PR00477 Phosphoglycerate kinase family signature 366 383 1.4E-84 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13610 9062ecd14e028481b4f7c780e47d2a3b 389 PRINTS PR00477 Phosphoglycerate kinase family signature 8 24 1.4E-84 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13610 9062ecd14e028481b4f7c780e47d2a3b 389 PRINTS PR00477 Phosphoglycerate kinase family signature 134 156 1.4E-84 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13610 9062ecd14e028481b4f7c780e47d2a3b 389 PRINTS PR00477 Phosphoglycerate kinase family signature 343 354 1.4E-84 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13610 9062ecd14e028481b4f7c780e47d2a3b 389 PRINTS PR00477 Phosphoglycerate kinase family signature 164 186 1.4E-84 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13610 9062ecd14e028481b4f7c780e47d2a3b 389 PRINTS PR00477 Phosphoglycerate kinase family signature 309 334 1.4E-84 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13610 9062ecd14e028481b4f7c780e47d2a3b 389 PRINTS PR00477 Phosphoglycerate kinase family signature 29 51 1.4E-84 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13610 9062ecd14e028481b4f7c780e47d2a3b 389 PRINTS PR00477 Phosphoglycerate kinase family signature 106 121 1.4E-84 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13610 9062ecd14e028481b4f7c780e47d2a3b 389 Pfam PF00162 Phosphoglycerate kinase 5 378 1.1E-146 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13610 9062ecd14e028481b4f7c780e47d2a3b 389 Gene3D G3DSA:3.40.50.1260 178 389 2.2E-90 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13610 9062ecd14e028481b4f7c780e47d2a3b 389 Gene3D G3DSA:3.40.50.1260 1 177 4.8E-73 T 12-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13610 9062ecd14e028481b4f7c780e47d2a3b 389 SUPERFAMILY SSF53748 2 389 2.71E-146 T 12-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13610 9062ecd14e028481b4f7c780e47d2a3b 389 PIRSF PIRSF000724 1 389 6.0E-137 T 12-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c05850 133eceffc49c112bcc5123396ff2e516 245 Gene3D G3DSA:3.40.50.720 1 245 9.0E-87 T 12-10-2018 TSC_c05850 133eceffc49c112bcc5123396ff2e516 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSC_c05850 133eceffc49c112bcc5123396ff2e516 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 243 1.5E-69 T 12-10-2018 TSC_c05850 133eceffc49c112bcc5123396ff2e516 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 6.6E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c05850 133eceffc49c112bcc5123396ff2e516 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 6.6E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c05850 133eceffc49c112bcc5123396ff2e516 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 6.6E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c05850 133eceffc49c112bcc5123396ff2e516 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 6.6E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c05850 133eceffc49c112bcc5123396ff2e516 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 6.6E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c05850 133eceffc49c112bcc5123396ff2e516 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 6.6E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c05850 133eceffc49c112bcc5123396ff2e516 245 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 4 242 6.6E-100 T 12-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TSC_c05850 133eceffc49c112bcc5123396ff2e516 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 183 8.0E-5 T 12-10-2018 TSC_c05850 133eceffc49c112bcc5123396ff2e516 245 SUPERFAMILY SSF51735 2 243 1.09E-86 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c05850 133eceffc49c112bcc5123396ff2e516 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 4.6E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c05850 133eceffc49c112bcc5123396ff2e516 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 4.6E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c05850 133eceffc49c112bcc5123396ff2e516 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 4.6E-15 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c06970 078535e86d02d16c34f31b09124ea3ab 198 SUPERFAMILY SSF52172 1 125 1.15E-24 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c06970 078535e86d02d16c34f31b09124ea3ab 198 Pfam PF00196 Bacterial regulatory proteins, luxR family 137 192 1.5E-13 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c06970 078535e86d02d16c34f31b09124ea3ab 198 Pfam PF00072 Response regulator receiver domain 3 108 1.0E-20 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c06970 078535e86d02d16c34f31b09124ea3ab 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 168 6.9E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c06970 078535e86d02d16c34f31b09124ea3ab 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 138 152 6.9E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c06970 078535e86d02d16c34f31b09124ea3ab 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 180 6.9E-10 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c06970 078535e86d02d16c34f31b09124ea3ab 198 SMART SM00421 135 192 4.4E-19 T 12-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 TSC_c06970 078535e86d02d16c34f31b09124ea3ab 198 Gene3D G3DSA:3.40.50.12740 1 198 4.1E-48 T 12-10-2018 TSC_c06970 078535e86d02d16c34f31b09124ea3ab 198 SUPERFAMILY SSF46894 129 197 6.8E-18 T 12-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 TSC_c06970 078535e86d02d16c34f31b09124ea3ab 198 SMART SM00448 1 108 4.0E-27 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c06800 2b33a7c7c9d877c0f1054145acc6d014 165 Gene3D G3DSA:3.40.50.1240 2 164 1.1E-22 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TSC_c06800 2b33a7c7c9d877c0f1054145acc6d014 165 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 80 4.9E-6 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSC_c06800 2b33a7c7c9d877c0f1054145acc6d014 165 SUPERFAMILY SSF53254 1 144 5.35E-16 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TSC_c07140 40ad126682479876f0cfb242124b1f57 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 368 382 5.6E-19 T 12-10-2018 IPR003004 GspF/PilC family TSC_c07140 40ad126682479876f0cfb242124b1f57 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 164 192 5.6E-19 T 12-10-2018 IPR003004 GspF/PilC family TSC_c07140 40ad126682479876f0cfb242124b1f57 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 66 78 5.6E-19 T 12-10-2018 IPR003004 GspF/PilC family TSC_c07140 40ad126682479876f0cfb242124b1f57 406 PRINTS PR00812 Bacterial general secretion pathway protein F signature 384 403 5.6E-19 T 12-10-2018 IPR003004 GspF/PilC family TSC_c07140 40ad126682479876f0cfb242124b1f57 406 Pfam PF00482 Type II secretion system (T2SS), protein F 70 192 1.0E-32 T 12-10-2018 IPR018076 Type II secretion system F domain TSC_c07140 40ad126682479876f0cfb242124b1f57 406 Pfam PF00482 Type II secretion system (T2SS), protein F 272 395 4.4E-30 T 12-10-2018 IPR018076 Type II secretion system F domain TSC_c07140 40ad126682479876f0cfb242124b1f57 406 Gene3D G3DSA:1.20.81.30 255 367 1.8E-28 T 12-10-2018 TSC_c07140 40ad126682479876f0cfb242124b1f57 406 Gene3D G3DSA:1.20.81.30 53 168 1.3E-34 T 12-10-2018 TSC_c07140 40ad126682479876f0cfb242124b1f57 406 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 164 192 - T 12-10-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 TSC_c07310 c57cee691db60948b5e28f77cd6b79d2 298 SUPERFAMILY SSF56281 9 253 6.68E-52 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c07310 c57cee691db60948b5e28f77cd6b79d2 298 Pfam PF00753 Metallo-beta-lactamase superfamily 17 209 2.2E-22 T 12-10-2018 IPR001279 Metallo-beta-lactamase TSC_c07310 c57cee691db60948b5e28f77cd6b79d2 298 SMART SM00849 15 209 1.5E-33 T 12-10-2018 IPR001279 Metallo-beta-lactamase TSC_c07310 c57cee691db60948b5e28f77cd6b79d2 298 Gene3D G3DSA:3.60.15.10 2 234 1.9E-58 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c00800 8ca60b0faced414a9a4bd938711855b0 169 Pfam PF10881 Protein of unknown function (DUF2726) 40 159 6.7E-35 T 12-10-2018 IPR024402 Domain of unknown function DUF2726 TSC_c22830 7cf0b9de1400bc4f60979dcbcaa2dc3c 227 Pfam PF00106 short chain dehydrogenase 5 189 3.5E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c22830 7cf0b9de1400bc4f60979dcbcaa2dc3c 227 Gene3D G3DSA:3.40.50.720 1 220 3.3E-38 T 12-10-2018 TSC_c22830 7cf0b9de1400bc4f60979dcbcaa2dc3c 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 4.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c22830 7cf0b9de1400bc4f60979dcbcaa2dc3c 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 4.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c22830 7cf0b9de1400bc4f60979dcbcaa2dc3c 227 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 193 213 4.9E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c22830 7cf0b9de1400bc4f60979dcbcaa2dc3c 227 SUPERFAMILY SSF51735 2 215 1.4E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c02220 fc41535bf345a61070b1592e3f9b6476 101 SUPERFAMILY SSF54995 1 96 2.88E-26 T 12-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c02220 fc41535bf345a61070b1592e3f9b6476 101 Gene3D G3DSA:3.30.70.60 55 98 2.4E-16 T 12-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 TSC_c02220 fc41535bf345a61070b1592e3f9b6476 101 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 19.054 T 12-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 TSC_c02220 fc41535bf345a61070b1592e3f9b6476 101 ProSitePatterns PS01048 Ribosomal protein S6 signature. 44 53 - T 12-10-2018 IPR020815 Ribosomal protein S6, conserved site GO:0003735|GO:0005840|GO:0006412|GO:0019843 TSC_c02220 fc41535bf345a61070b1592e3f9b6476 101 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 1.1E-20 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c02220 fc41535bf345a61070b1592e3f9b6476 101 Pfam PF01250 Ribosomal protein S6 3 92 5.9E-23 T 12-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c02220 fc41535bf345a61070b1592e3f9b6476 101 Gene3D G3DSA:3.30.70.60 1 54 1.4E-18 T 12-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 TSC_c13490 69c527516f28c4fc0b5b6e392ad8bf57 346 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 16 329 3.3E-131 T 12-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 TSC_c13490 69c527516f28c4fc0b5b6e392ad8bf57 346 Gene3D G3DSA:3.40.50.970 3 341 1.4E-111 T 12-10-2018 TSC_c13490 69c527516f28c4fc0b5b6e392ad8bf57 346 Pfam PF00676 Dehydrogenase E1 component 25 314 4.3E-85 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TSC_c13490 69c527516f28c4fc0b5b6e392ad8bf57 346 SUPERFAMILY SSF52518 13 330 7.92E-98 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c24550 e750ace6e7c755530637cb1ef49bf8fc 215 SUPERFAMILY SSF53254 15 207 1.5E-34 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TSC_c24550 e750ace6e7c755530637cb1ef49bf8fc 215 Gene3D G3DSA:3.40.50.1240 15 214 1.8E-35 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TSC_c24550 e750ace6e7c755530637cb1ef49bf8fc 215 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 17 207 7.5E-38 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSC_c24550 e750ace6e7c755530637cb1ef49bf8fc 215 PIRSF PIRSF000709 84 148 3.3E-4 T 12-10-2018 TSC_c04760 35477e02492518cdf64f8c1e1b89e5b1 1116 Pfam PF04465 Protein of unknown function (DUF499) 299 817 6.0E-26 T 12-10-2018 IPR007555 Protein of unknown function DUF499 TSC_c11990 ba4fa234149e7b2169f7d15c53e4a63f 493 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 62 412 1.7E-95 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TSC_c11990 ba4fa234149e7b2169f7d15c53e4a63f 493 Gene3D G3DSA:3.10.105.10 252 467 4.6E-139 T 12-10-2018 TSC_c11990 ba4fa234149e7b2169f7d15c53e4a63f 493 Gene3D G3DSA:3.40.190.10 177 476 4.6E-139 T 12-10-2018 TSC_c11990 ba4fa234149e7b2169f7d15c53e4a63f 493 PIRSF PIRSF002741 14 489 4.3E-119 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSC_c11990 ba4fa234149e7b2169f7d15c53e4a63f 493 SUPERFAMILY SSF53850 17 492 2.04E-146 T 12-10-2018 TSC_c11990 ba4fa234149e7b2169f7d15c53e4a63f 493 Gene3D G3DSA:3.90.76.10 29 176 4.6E-139 T 12-10-2018 TSC_c07820 64849550a30a714c8d977a5c4ad55181 552 Hamap MF_00900 GTPase HflX [hflX]. 205 541 41.354 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 TSC_c07820 64849550a30a714c8d977a5c4ad55181 552 SUPERFAMILY SSF52540 376 538 3.97E-31 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c07820 64849550a30a714c8d977a5c4ad55181 552 Gene3D G3DSA:3.40.50.300 375 540 9.4E-31 T 12-10-2018 TSC_c07820 64849550a30a714c8d977a5c4ad55181 552 Pfam PF16360 GTP-binding GTPase Middle Region 292 370 5.9E-29 T 12-10-2018 IPR032305 GTP-binding protein, middle domain TSC_c07820 64849550a30a714c8d977a5c4ad55181 552 Gene3D G3DSA:3.40.50.11060 197 316 1.5E-34 T 12-10-2018 TSC_c07820 64849550a30a714c8d977a5c4ad55181 552 Pfam PF01926 50S ribosome-binding GTPase 378 480 2.6E-13 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c07820 64849550a30a714c8d977a5c4ad55181 552 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 378 398 2.5E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c07820 64849550a30a714c8d977a5c4ad55181 552 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 445 463 2.5E-7 T 12-10-2018 IPR006073 GTP binding domain GO:0005525 TSC_c07820 64849550a30a714c8d977a5c4ad55181 552 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 187 535 4.5E-124 T 12-10-2018 IPR016496 GTPase HflX GO:0005525 TSC_c07820 64849550a30a714c8d977a5c4ad55181 552 Pfam PF13167 GTP-binding GTPase N-terminal 203 290 3.0E-26 T 12-10-2018 IPR025121 GTPase HflX, N-terminal TSC_c18950 cf351b24816daaf8cca689cac113df6a 184 Gene3D G3DSA:3.40.50.880 1 183 1.6E-48 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c18950 cf351b24816daaf8cca689cac113df6a 184 Pfam PF01965 DJ-1/PfpI family 1 176 6.0E-44 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TSC_c18950 cf351b24816daaf8cca689cac113df6a 184 SUPERFAMILY SSF52317 1 180 1.08E-47 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c18950 cf351b24816daaf8cca689cac113df6a 184 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 2 180 1.8E-47 T 12-10-2018 IPR006286 Deglycase PfpI TSC_c20280 1741ca8c85b24c49b4d6a7244c8d13b6 184 Pfam PF01025 GrpE 17 173 3.3E-39 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TSC_c20280 1741ca8c85b24c49b4d6a7244c8d13b6 184 ProSitePatterns PS01071 grpE protein signature. 132 172 - T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TSC_c20280 1741ca8c85b24c49b4d6a7244c8d13b6 184 Gene3D G3DSA:3.90.20.20 3 120 2.5E-33 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 TSC_c20280 1741ca8c85b24c49b4d6a7244c8d13b6 184 Gene3D G3DSA:2.30.22.10 121 182 1.1E-23 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 TSC_c20280 1741ca8c85b24c49b4d6a7244c8d13b6 184 SUPERFAMILY SSF58014 29 121 9.15E-22 T 12-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 TSC_c20280 1741ca8c85b24c49b4d6a7244c8d13b6 184 Hamap MF_01151 Protein GrpE [grpE]. 2 174 18.126 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TSC_c20280 1741ca8c85b24c49b4d6a7244c8d13b6 184 PRINTS PR00773 GrpE protein signature 153 172 3.1E-26 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TSC_c20280 1741ca8c85b24c49b4d6a7244c8d13b6 184 PRINTS PR00773 GrpE protein signature 129 144 3.1E-26 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TSC_c20280 1741ca8c85b24c49b4d6a7244c8d13b6 184 PRINTS PR00773 GrpE protein signature 77 92 3.1E-26 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TSC_c20280 1741ca8c85b24c49b4d6a7244c8d13b6 184 PRINTS PR00773 GrpE protein signature 49 65 3.1E-26 T 12-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 TSC_c20280 1741ca8c85b24c49b4d6a7244c8d13b6 184 SUPERFAMILY SSF51064 122 175 1.02E-11 T 12-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 TSC_c17580 47d02f31826c01ab8b07480c78a53428 536 Gene3D G3DSA:2.140.10.20 114 536 2.1E-165 T 12-10-2018 IPR003143 Cytochrome cd1-nitrite reductase, C-terminal domain superfamily TSC_c17580 47d02f31826c01ab8b07480c78a53428 536 Gene3D G3DSA:1.10.760.10 13 111 1.1E-30 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c17580 47d02f31826c01ab8b07480c78a53428 536 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 30 103 3.9E-10 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c17580 47d02f31826c01ab8b07480c78a53428 536 Pfam PF02239 Cytochrome D1 heme domain 140 531 1.2E-109 T 12-10-2018 TSC_c17580 47d02f31826c01ab8b07480c78a53428 536 SUPERFAMILY SSF51004 115 536 1.2E-95 T 12-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily TSC_c17580 47d02f31826c01ab8b07480c78a53428 536 SUPERFAMILY SSF46626 7 124 1.58E-20 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c22210 cd65ded905bbdb7171d12524bb10f4e8 72 Pfam PF01176 Translation initiation factor 1A / IF-1 10 71 5.5E-27 T 12-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 TSC_c22210 cd65ded905bbdb7171d12524bb10f4e8 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 24.32 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 TSC_c22210 cd65ded905bbdb7171d12524bb10f4e8 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 6 72 1.5E-33 T 12-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 TSC_c22210 cd65ded905bbdb7171d12524bb10f4e8 72 SUPERFAMILY SSF50249 4 71 1.69E-25 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c22210 cd65ded905bbdb7171d12524bb10f4e8 72 Gene3D G3DSA:2.40.50.140 2 72 3.9E-37 T 12-10-2018 TSC_c23070 cc73de4a053c88faa172bbc57f1afee3 86 SUPERFAMILY SSF52833 5 77 1.02E-13 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TSC_c23070 cc73de4a053c88faa172bbc57f1afee3 86 Gene3D G3DSA:3.40.30.10 5 83 1.9E-12 T 12-10-2018 TSC_c23070 cc73de4a053c88faa172bbc57f1afee3 86 Pfam PF05768 Glutaredoxin-like domain (DUF836) 7 58 2.1E-8 T 12-10-2018 IPR008554 Glutaredoxin-like TSC_c13640 ed7fb0e2e7917515185f302290303676 236 Gene3D G3DSA:3.60.110.10 1 236 1.8E-45 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSC_c13640 ed7fb0e2e7917515185f302290303676 236 SUPERFAMILY SSF56317 1 235 1.7E-41 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSC_c13640 ed7fb0e2e7917515185f302290303676 236 Pfam PF00795 Carbon-nitrogen hydrolase 6 219 3.8E-19 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TSC_c21000 6c4af9cf35ca66f054db295932cde098 182 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 53 137 4.1E-10 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c21000 6c4af9cf35ca66f054db295932cde098 182 Gene3D G3DSA:1.10.760.10 28 165 4.5E-45 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c21000 6c4af9cf35ca66f054db295932cde098 182 SUPERFAMILY SSF46626 8 143 2.23E-18 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c12890 34e6f0c044128c8cb6e95733c24d6012 388 Pfam PF13416 Bacterial extracellular solute-binding protein 60 331 1.0E-25 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSC_c12890 34e6f0c044128c8cb6e95733c24d6012 388 SUPERFAMILY SSF53850 37 360 5.06E-58 T 12-10-2018 TSC_c12890 34e6f0c044128c8cb6e95733c24d6012 388 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 66 87 1.0E-8 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c12890 34e6f0c044128c8cb6e95733c24d6012 388 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 140 156 1.0E-8 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c12890 34e6f0c044128c8cb6e95733c24d6012 388 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 280 299 1.0E-8 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c12890 34e6f0c044128c8cb6e95733c24d6012 388 Gene3D G3DSA:3.40.190.10 43 331 1.5E-55 T 12-10-2018 TSC_c12890 34e6f0c044128c8cb6e95733c24d6012 388 Gene3D G3DSA:3.40.190.10 149 287 1.5E-55 T 12-10-2018 TSC_c06460 99a1a3e2914eb187aeb91c4ed4e38112 181 Hamap MF_00146 dCTP deaminase [dcd]. 1 181 28.175 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TSC_c06460 99a1a3e2914eb187aeb91c4ed4e38112 181 SUPERFAMILY SSF51283 1 180 3.53E-50 T 12-10-2018 IPR036157 dUTPase-like superfamily TSC_c06460 99a1a3e2914eb187aeb91c4ed4e38112 181 Pfam PF00692 dUTPase 73 177 5.2E-7 T 12-10-2018 IPR029054 dUTPase-like TSC_c06460 99a1a3e2914eb187aeb91c4ed4e38112 181 Gene3D G3DSA:2.70.40.10 1 154 1.7E-48 T 12-10-2018 IPR036157 dUTPase-like superfamily TSC_c06460 99a1a3e2914eb187aeb91c4ed4e38112 181 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 9 181 1.8E-48 T 12-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 TSC_c23640 0b56482d19b61e2cc2d846c4faff9b82 241 SUPERFAMILY SSF46626 104 237 2.96E-27 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c23640 0b56482d19b61e2cc2d846c4faff9b82 241 PRINTS PR00605 Class IC cytochrome C signature 167 178 5.3E-8 T 12-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 TSC_c23640 0b56482d19b61e2cc2d846c4faff9b82 241 PRINTS PR00605 Class IC cytochrome C signature 207 229 5.3E-8 T 12-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 TSC_c23640 0b56482d19b61e2cc2d846c4faff9b82 241 Gene3D G3DSA:1.10.760.10 124 235 5.1E-23 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c23640 0b56482d19b61e2cc2d846c4faff9b82 241 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 157 229 5.1E-17 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c09090 863e5ba6ce3841798fcdcfb48e83fe5c 257 Pfam PF12697 Alpha/beta hydrolase family 15 247 3.2E-16 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSC_c09090 863e5ba6ce3841798fcdcfb48e83fe5c 257 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 3.7E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSC_c09090 863e5ba6ce3841798fcdcfb48e83fe5c 257 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 94 3.7E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSC_c09090 863e5ba6ce3841798fcdcfb48e83fe5c 257 PRINTS PR00111 Alpha/beta hydrolase fold signature 200 214 3.7E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSC_c09090 863e5ba6ce3841798fcdcfb48e83fe5c 257 PRINTS PR00111 Alpha/beta hydrolase fold signature 37 52 3.7E-9 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSC_c09090 863e5ba6ce3841798fcdcfb48e83fe5c 257 SUPERFAMILY SSF53474 3 253 3.92E-55 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c09090 863e5ba6ce3841798fcdcfb48e83fe5c 257 Gene3D G3DSA:3.40.50.1820 1 254 8.1E-56 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c17910 d876960005294eb1fa360c0a2ffda270 375 SUPERFAMILY SSF102114 10 349 8.11E-47 T 12-10-2018 TSC_c17910 d876960005294eb1fa360c0a2ffda270 375 Pfam PF04055 Radical SAM superfamily 54 220 3.7E-14 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSC_c17910 d876960005294eb1fa360c0a2ffda270 375 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 46 357 9.1E-97 T 12-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 TSC_c17910 d876960005294eb1fa360c0a2ffda270 375 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 10 360 50.001 T 12-10-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 TSC_c17910 d876960005294eb1fa360c0a2ffda270 375 Gene3D G3DSA:3.20.20.70 1 348 1.5E-43 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c17910 d876960005294eb1fa360c0a2ffda270 375 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 11 357 1.3E-130 T 12-10-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 TSC_c17910 d876960005294eb1fa360c0a2ffda270 375 PIRSF PIRSF004762 1 368 1.3E-92 T 12-10-2018 TSC_c09720 47571575df316e6cabaff30666111d69 437 Gene3D G3DSA:3.30.70.360 178 347 5.8E-150 T 12-10-2018 TSC_c09720 47571575df316e6cabaff30666111d69 437 SUPERFAMILY SSF53187 7 431 4.65E-54 T 12-10-2018 TSC_c09720 47571575df316e6cabaff30666111d69 437 Pfam PF07687 Peptidase dimerisation domain 176 333 8.4E-20 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain TSC_c09720 47571575df316e6cabaff30666111d69 437 Gene3D G3DSA:3.40.630.10 11 419 5.8E-150 T 12-10-2018 TSC_c09720 47571575df316e6cabaff30666111d69 437 SUPERFAMILY SSF55031 185 331 6.63E-5 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSC_c09720 47571575df316e6cabaff30666111d69 437 Pfam PF01546 Peptidase family M20/M25/M40 65 431 5.9E-35 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 TSC_c02440 6a1a2d0daea52b13f056da0f5a8bd0a3 348 Gene3D G3DSA:2.160.10.10 234 312 3.4E-7 T 12-10-2018 TSC_c02440 6a1a2d0daea52b13f056da0f5a8bd0a3 348 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 2 347 1.6E-138 T 12-10-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form TSC_c02440 6a1a2d0daea52b13f056da0f5a8bd0a3 348 Gene3D G3DSA:3.90.550.10 1 233 1.1E-70 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c02440 6a1a2d0daea52b13f056da0f5a8bd0a3 348 Pfam PF00483 Nucleotidyl transferase 2 229 5.1E-51 T 12-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 TSC_c02440 6a1a2d0daea52b13f056da0f5a8bd0a3 348 SUPERFAMILY SSF53448 2 280 1.46E-73 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c21800 6369be67554f3e8deaa1f72394b09d45 84 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 12 83 4.0E-29 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSC_c21800 6369be67554f3e8deaa1f72394b09d45 84 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 6 78 1.6E-20 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSC_c21800 6369be67554f3e8deaa1f72394b09d45 84 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 4 79 17.629 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSC_c21800 6369be67554f3e8deaa1f72394b09d45 84 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 78 1.2E-15 T 12-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 TSC_c21800 6369be67554f3e8deaa1f72394b09d45 84 SUPERFAMILY SSF82697 4 80 1.38E-18 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSC_c21800 6369be67554f3e8deaa1f72394b09d45 84 Gene3D G3DSA:3.30.1280.10 1 84 5.7E-30 T 12-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSC_c17610 2448808284c96fcbdd933fa5e5c73a94 221 SUPERFAMILY SSF46626 113 208 3.81E-13 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c17610 2448808284c96fcbdd933fa5e5c73a94 221 Pfam PF00034 Cytochrome c 115 205 1.5E-7 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c17610 2448808284c96fcbdd933fa5e5c73a94 221 Gene3D G3DSA:1.10.760.10 98 219 2.5E-24 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c04320 a8670fa3ba0955655d7b74fca40db19c 79 Gene3D G3DSA:3.30.1360.20 1 78 8.3E-33 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TSC_c04320 a8670fa3ba0955655d7b74fca40db19c 79 SUPERFAMILY SSF55248 2 77 9.29E-29 T 12-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TSC_c04320 a8670fa3ba0955655d7b74fca40db19c 79 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 2 75 3.0E-27 T 12-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 TSC_c05130 ac9d667f6704e10e676cb32613d84bc6 234 Gene3D G3DSA:1.10.760.10 32 90 4.9E-10 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c05130 ac9d667f6704e10e676cb32613d84bc6 234 Gene3D G3DSA:1.10.760.10 108 234 2.8E-39 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c05130 ac9d667f6704e10e676cb32613d84bc6 234 Pfam PF00034 Cytochrome c 109 194 6.4E-8 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c05130 ac9d667f6704e10e676cb32613d84bc6 234 SUPERFAMILY SSF46626 32 101 3.1E-12 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c05130 ac9d667f6704e10e676cb32613d84bc6 234 SUPERFAMILY SSF46626 110 212 1.21E-18 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c23240 c7c5624c1fc44b46b04d65986d937074 126 SUPERFAMILY SSF89360 6 100 1.82E-30 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TSC_c23240 c7c5624c1fc44b46b04d65986d937074 126 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 95 112 - T 12-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 TSC_c23240 c7c5624c1fc44b46b04d65986d937074 126 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 9 113 6.3E-37 T 12-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 TSC_c23240 c7c5624c1fc44b46b04d65986d937074 126 Pfam PF01521 Iron-sulphur cluster biosynthesis 9 109 2.5E-18 T 12-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 TSC_c23240 c7c5624c1fc44b46b04d65986d937074 126 Gene3D G3DSA:2.60.300.12 8 116 6.5E-36 T 12-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 TSC_c22950 b535cf71606472de6b9e4278a7ffc850 450 SUPERFAMILY SSF54184 166 227 1.7E-5 T 12-10-2018 TSC_c22950 b535cf71606472de6b9e4278a7ffc850 450 Gene3D G3DSA:3.30.10.20 302 363 1.1E-12 T 12-10-2018 TSC_c22950 b535cf71606472de6b9e4278a7ffc850 450 Gene3D G3DSA:3.30.10.20 167 227 4.6E-14 T 12-10-2018 TSC_c22950 b535cf71606472de6b9e4278a7ffc850 450 Gene3D G3DSA:3.30.10.20 231 295 2.3E-13 T 12-10-2018 TSC_c22950 b535cf71606472de6b9e4278a7ffc850 450 Pfam PF03793 PASTA domain 167 227 1.2E-11 T 12-10-2018 IPR005543 PASTA domain TSC_c22950 b535cf71606472de6b9e4278a7ffc850 450 Pfam PF03793 PASTA domain 234 293 2.3E-10 T 12-10-2018 IPR005543 PASTA domain TSC_c22950 b535cf71606472de6b9e4278a7ffc850 450 Pfam PF03793 PASTA domain 304 361 8.0E-11 T 12-10-2018 IPR005543 PASTA domain TSC_c22950 b535cf71606472de6b9e4278a7ffc850 450 SMART SM00740 228 294 1.3E-4 T 12-10-2018 IPR005543 PASTA domain TSC_c22950 b535cf71606472de6b9e4278a7ffc850 450 SMART SM00740 298 363 5.9E-8 T 12-10-2018 IPR005543 PASTA domain TSC_c22950 b535cf71606472de6b9e4278a7ffc850 450 SMART SM00740 162 227 1.8E-10 T 12-10-2018 IPR005543 PASTA domain TSC_c18160 fb7bd71132da28e10a95fa7e60c77a56 126 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 125 10.523 T 12-10-2018 IPR022907 VapC family GO:0004540 TSC_c18160 fb7bd71132da28e10a95fa7e60c77a56 126 Gene3D G3DSA:3.40.50.1010 1 121 5.9E-22 T 12-10-2018 TSC_c18160 fb7bd71132da28e10a95fa7e60c77a56 126 Pfam PF01850 PIN domain 3 114 7.9E-11 T 12-10-2018 IPR002716 PIN domain TSC_c18160 fb7bd71132da28e10a95fa7e60c77a56 126 SUPERFAMILY SSF88723 1 117 4.21E-24 T 12-10-2018 IPR029060 PIN-like domain superfamily TSC_c10770 283bed9a2ed3e5d2ce88e1b219b23fb6 274 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 2 50 2.3E-11 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TSC_c10770 283bed9a2ed3e5d2ce88e1b219b23fb6 274 Gene3D G3DSA:1.10.3720.10 64 269 1.5E-26 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c10770 283bed9a2ed3e5d2ce88e1b219b23fb6 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 272 1.1E-35 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c10770 283bed9a2ed3e5d2ce88e1b219b23fb6 274 SUPERFAMILY SSF161098 67 255 7.19E-31 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c06190 ab4370be22ff366d6cb904cec326055c 201 Pfam PF00117 Glutamine amidotransferase class-I 5 120 2.1E-8 T 12-10-2018 IPR017926 Glutamine amidotransferase TSC_c06190 ab4370be22ff366d6cb904cec326055c 201 PIRSF PIRSF000495 1 187 6.0E-45 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TSC_c06190 ab4370be22ff366d6cb904cec326055c 201 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 170 1.9E-39 T 12-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 TSC_c06190 ab4370be22ff366d6cb904cec326055c 201 SUPERFAMILY SSF52317 1 165 7.02E-37 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c06190 ab4370be22ff366d6cb904cec326055c 201 Gene3D G3DSA:3.40.50.880 1 174 6.7E-52 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c04780 e9dbff9406bda65c864d13e5b2d6fd4c 1189 SMART SM00490 540 625 7.2E-24 T 12-10-2018 IPR001650 Helicase, C-terminal TSC_c04780 e9dbff9406bda65c864d13e5b2d6fd4c 1189 Pfam PF00271 Helicase conserved C-terminal domain 524 625 3.1E-20 T 12-10-2018 IPR001650 Helicase, C-terminal TSC_c04780 e9dbff9406bda65c864d13e5b2d6fd4c 1189 Gene3D G3DSA:3.40.50.10810 102 377 1.5E-60 T 12-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily TSC_c04780 e9dbff9406bda65c864d13e5b2d6fd4c 1189 Pfam PF00176 SNF2 family N-terminal domain 125 359 4.5E-18 T 12-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 TSC_c04780 e9dbff9406bda65c864d13e5b2d6fd4c 1189 SUPERFAMILY SSF52540 224 665 1.81E-48 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c04780 e9dbff9406bda65c864d13e5b2d6fd4c 1189 SUPERFAMILY SSF52540 90 291 1.31E-36 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c04780 e9dbff9406bda65c864d13e5b2d6fd4c 1189 SMART SM00487 100 302 1.4E-21 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSC_c04780 e9dbff9406bda65c864d13e5b2d6fd4c 1189 Pfam PF13020 Domain of unknown function (DUF3883) 1073 1159 1.0E-18 T 12-10-2018 IPR024975 Domain of unknown function DUF3883 TSC_c04780 e9dbff9406bda65c864d13e5b2d6fd4c 1189 Gene3D G3DSA:3.40.50.300 436 655 4.5E-41 T 12-10-2018 TSC_c21400 6cb953281231d0366c30079bb05a2d6e 199 Gene3D G3DSA:3.40.50.300 1 197 2.5E-68 T 12-10-2018 TSC_c21400 6cb953281231d0366c30079bb05a2d6e 199 SUPERFAMILY SSF52540 1 192 1.37E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c21400 6cb953281231d0366c30079bb05a2d6e 199 Pfam PF02223 Thymidylate kinase 8 190 3.0E-54 T 12-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 TSC_c21400 6cb953281231d0366c30079bb05a2d6e 199 Hamap MF_00165 Thymidylate kinase [tmk]. 4 198 30.852 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TSC_c21400 6cb953281231d0366c30079bb05a2d6e 199 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 2 190 1.5E-53 T 12-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TSC_c21400 6cb953281231d0366c30079bb05a2d6e 199 ProSitePatterns PS01331 Thymidylate kinase signature. 89 101 - T 12-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 TSC_c23370 e7a0844b840950fe93cfa66318907ff4 398 Gene3D G3DSA:3.40.190.10 36 354 1.6E-140 T 12-10-2018 TSC_c23370 e7a0844b840950fe93cfa66318907ff4 398 SUPERFAMILY SSF53850 20 392 4.04E-83 T 12-10-2018 TSC_c23370 e7a0844b840950fe93cfa66318907ff4 398 Pfam PF13416 Bacterial extracellular solute-binding protein 39 337 2.7E-47 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSC_c23370 e7a0844b840950fe93cfa66318907ff4 398 Gene3D G3DSA:3.40.190.10 133 370 1.6E-140 T 12-10-2018 TSC_c23370 e7a0844b840950fe93cfa66318907ff4 398 PRINTS PR00181 Maltose binding protein signature 354 373 1.5E-15 T 12-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TSC_c23370 e7a0844b840950fe93cfa66318907ff4 398 PRINTS PR00181 Maltose binding protein signature 124 143 1.5E-15 T 12-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TSC_c23370 e7a0844b840950fe93cfa66318907ff4 398 PRINTS PR00181 Maltose binding protein signature 165 184 1.5E-15 T 12-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TSC_c23370 e7a0844b840950fe93cfa66318907ff4 398 PRINTS PR00181 Maltose binding protein signature 230 249 1.5E-15 T 12-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TSC_c23370 e7a0844b840950fe93cfa66318907ff4 398 PRINTS PR00181 Maltose binding protein signature 145 164 1.5E-15 T 12-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 TSC_c03120 751941b9eab2a316b4136b533158befe 124 Pfam PF02410 Ribosomal silencing factor during starvation 25 118 1.1E-24 T 12-10-2018 TSC_c03120 751941b9eab2a316b4136b533158befe 124 Gene3D G3DSA:3.30.460.10 13 122 1.0E-34 T 12-10-2018 TSC_c03120 751941b9eab2a316b4136b533158befe 124 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 22 118 3.5E-32 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS TSC_c03120 751941b9eab2a316b4136b533158befe 124 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 15 119 23.194 T 12-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS TSC_c03120 751941b9eab2a316b4136b533158befe 124 SUPERFAMILY SSF81301 18 123 5.23E-33 T 12-10-2018 TSC_c24330 c62b638ca7e27a4d9af4cd1d773bb2e2 191 Hamap MF_00163 Peptide deformylase [def]. 1 173 30.825 T 12-10-2018 IPR023635 Peptide deformylase TSC_c24330 c62b638ca7e27a4d9af4cd1d773bb2e2 191 SUPERFAMILY SSF56420 1 170 1.02E-57 T 12-10-2018 IPR036821 Peptide deformylase superfamily TSC_c24330 c62b638ca7e27a4d9af4cd1d773bb2e2 191 Pfam PF01327 Polypeptide deformylase 3 163 9.0E-50 T 12-10-2018 IPR023635 Peptide deformylase TSC_c24330 c62b638ca7e27a4d9af4cd1d773bb2e2 191 PRINTS PR01576 Peptide deformylase signature 31 60 1.5E-37 T 12-10-2018 IPR023635 Peptide deformylase TSC_c24330 c62b638ca7e27a4d9af4cd1d773bb2e2 191 PRINTS PR01576 Peptide deformylase signature 99 110 1.5E-37 T 12-10-2018 IPR023635 Peptide deformylase TSC_c24330 c62b638ca7e27a4d9af4cd1d773bb2e2 191 PRINTS PR01576 Peptide deformylase signature 112 130 1.5E-37 T 12-10-2018 IPR023635 Peptide deformylase TSC_c24330 c62b638ca7e27a4d9af4cd1d773bb2e2 191 PRINTS PR01576 Peptide deformylase signature 131 160 1.5E-37 T 12-10-2018 IPR023635 Peptide deformylase TSC_c24330 c62b638ca7e27a4d9af4cd1d773bb2e2 191 Gene3D G3DSA:3.90.45.10 1 191 7.9E-78 T 12-10-2018 IPR036821 Peptide deformylase superfamily TSC_c24330 c62b638ca7e27a4d9af4cd1d773bb2e2 191 PIRSF PIRSF004749 1 188 3.4E-49 T 12-10-2018 IPR023635 Peptide deformylase TSC_c24330 c62b638ca7e27a4d9af4cd1d773bb2e2 191 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 7 169 6.4E-40 T 12-10-2018 IPR023635 Peptide deformylase TSC_c00510 219e2996e009aed87c7771c20965f2d1 272 Pfam PF00294 pfkB family carbohydrate kinase 2 183 5.1E-14 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB TSC_c00510 219e2996e009aed87c7771c20965f2d1 272 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 27 51 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TSC_c00510 219e2996e009aed87c7771c20965f2d1 272 SUPERFAMILY SSF53613 4 184 5.54E-28 T 12-10-2018 IPR029056 Ribokinase-like TSC_c00510 219e2996e009aed87c7771c20965f2d1 272 Gene3D G3DSA:3.40.1190.20 2 196 4.5E-34 T 12-10-2018 IPR029056 Ribokinase-like TSC_c15120 50d43fddec6184114a594f5cdee24247 253 Pfam PF14332 Domain of unknown function (DUF4388) 3 100 2.1E-17 T 12-10-2018 IPR025497 Domain of unknown function DUF4388 TSC_c11230 d428312be98200255a41a85b11d7229a 208 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 31 199 7.8E-31 T 12-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 TSC_c11230 d428312be98200255a41a85b11d7229a 208 Gene3D G3DSA:3.40.50.1360 11 205 3.4E-34 T 12-10-2018 TSC_c11230 d428312be98200255a41a85b11d7229a 208 SUPERFAMILY SSF100950 30 202 4.19E-36 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TSC_c05170 1c12cbfedc809e18378b0b42c3efec89 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 236 258 3.4E-59 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TSC_c05170 1c12cbfedc809e18378b0b42c3efec89 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 90 112 3.4E-59 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TSC_c05170 1c12cbfedc809e18378b0b42c3efec89 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 6 32 3.4E-59 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TSC_c05170 1c12cbfedc809e18378b0b42c3efec89 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 112 139 3.4E-59 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TSC_c05170 1c12cbfedc809e18378b0b42c3efec89 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 258 283 3.4E-59 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TSC_c05170 1c12cbfedc809e18378b0b42c3efec89 285 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 39 51 3.4E-59 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TSC_c05170 1c12cbfedc809e18378b0b42c3efec89 285 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 1 284 47.433 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TSC_c05170 1c12cbfedc809e18378b0b42c3efec89 285 Pfam PF01842 ACT domain 5 60 8.1E-11 T 12-10-2018 IPR002912 ACT domain TSC_c05170 1c12cbfedc809e18378b0b42c3efec89 285 PIRSF PIRSF036480 1 285 4.8E-114 T 12-10-2018 TSC_c05170 1c12cbfedc809e18378b0b42c3efec89 285 Gene3D G3DSA:3.30.70.260 1 88 9.6E-31 T 12-10-2018 TSC_c05170 1c12cbfedc809e18378b0b42c3efec89 285 SUPERFAMILY SSF53328 89 284 1.31E-59 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TSC_c05170 1c12cbfedc809e18378b0b42c3efec89 285 Pfam PF00551 Formyl transferase 89 266 8.1E-40 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TSC_c05170 1c12cbfedc809e18378b0b42c3efec89 285 Gene3D G3DSA:3.40.50.170 89 285 4.2E-78 T 12-10-2018 TSC_c05170 1c12cbfedc809e18378b0b42c3efec89 285 SUPERFAMILY SSF55021 5 85 6.7E-17 T 12-10-2018 TSC_c05170 1c12cbfedc809e18378b0b42c3efec89 285 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 5 284 2.6E-122 T 12-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 TSC_c06290 07926676b90315b10941517b2ef34c63 133 Pfam PF01883 Iron-sulfur cluster assembly protein 33 106 7.6E-24 T 12-10-2018 IPR002744 MIP18 family-like TSC_c06290 07926676b90315b10941517b2ef34c63 133 SUPERFAMILY SSF117916 31 127 7.19E-34 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSC_c06290 07926676b90315b10941517b2ef34c63 133 Gene3D G3DSA:3.30.300.130 27 129 2.5E-38 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSC_c14970 a9a5b8d762d9e22d9c5004154800352c 245 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 18 241 29.335 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 TSC_c14970 a9a5b8d762d9e22d9c5004154800352c 245 SUPERFAMILY SSF51366 2 244 2.12E-72 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSC_c14970 a9a5b8d762d9e22d9c5004154800352c 245 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 39 56 - T 12-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 TSC_c14970 a9a5b8d762d9e22d9c5004154800352c 245 Pfam PF00218 Indole-3-glycerol phosphate synthase 24 243 3.4E-69 T 12-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 TSC_c14970 a9a5b8d762d9e22d9c5004154800352c 245 Gene3D G3DSA:3.20.20.70 1 245 1.2E-91 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c20030 4b215349e602bcbeb52c6b25b9515490 521 Gene3D G3DSA:3.40.50.300 1 207 1.9E-85 T 12-10-2018 TSC_c20030 4b215349e602bcbeb52c6b25b9515490 521 SMART SM00487 20 214 4.1E-63 T 12-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain TSC_c20030 4b215349e602bcbeb52c6b25b9515490 521 Pfam PF00270 DEAD/DEAH box helicase 25 191 2.6E-47 T 12-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 TSC_c20030 4b215349e602bcbeb52c6b25b9515490 521 SUPERFAMILY SSF52540 73 351 7.87E-73 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c20030 4b215349e602bcbeb52c6b25b9515490 521 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 12-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site TSC_c20030 4b215349e602bcbeb52c6b25b9515490 521 Gene3D G3DSA:3.30.70.1800 366 493 2.7E-54 T 12-10-2018 TSC_c20030 4b215349e602bcbeb52c6b25b9515490 521 Pfam PF00271 Helicase conserved C-terminal domain 225 332 8.0E-29 T 12-10-2018 IPR001650 Helicase, C-terminal TSC_c20030 4b215349e602bcbeb52c6b25b9515490 521 Gene3D G3DSA:3.40.50.300 218 364 6.0E-47 T 12-10-2018 TSC_c20030 4b215349e602bcbeb52c6b25b9515490 521 SMART SM00490 251 332 7.7E-34 T 12-10-2018 IPR001650 Helicase, C-terminal TSC_c06200 44c8ad9835afeef40de15f5c1b8c8440 308 Gene3D G3DSA:3.40.1190.20 1 307 1.5E-70 T 12-10-2018 IPR029056 Ribokinase-like TSC_c06200 44c8ad9835afeef40de15f5c1b8c8440 308 PRINTS PR00990 Ribokinase signature 104 117 8.2E-9 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TSC_c06200 44c8ad9835afeef40de15f5c1b8c8440 308 PRINTS PR00990 Ribokinase signature 219 230 8.2E-9 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TSC_c06200 44c8ad9835afeef40de15f5c1b8c8440 308 PRINTS PR00990 Ribokinase signature 32 51 8.2E-9 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TSC_c06200 44c8ad9835afeef40de15f5c1b8c8440 308 PRINTS PR00990 Ribokinase signature 5 26 8.2E-9 T 12-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 TSC_c06200 44c8ad9835afeef40de15f5c1b8c8440 308 SUPERFAMILY SSF53613 1 298 3.74E-68 T 12-10-2018 IPR029056 Ribokinase-like TSC_c06200 44c8ad9835afeef40de15f5c1b8c8440 308 Pfam PF00294 pfkB family carbohydrate kinase 4 292 1.1E-48 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB TSC_c03470 31c5aea49fefe3a78d265ac8070bf22e 171 SUPERFAMILY SSF46626 5 154 1.05E-15 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c03470 31c5aea49fefe3a78d265ac8070bf22e 171 Gene3D G3DSA:1.10.760.10 61 160 6.6E-12 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c03470 31c5aea49fefe3a78d265ac8070bf22e 171 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 73 152 1.7E-11 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c21110 35c124e719e74de1e1f047a0a46d568f 150 PIRSF PIRSF010312 1 150 9.6E-47 T 12-10-2018 IPR016568 Sulphur oxidation, SoxY TSC_c21110 35c124e719e74de1e1f047a0a46d568f 150 TIGRFAM TIGR04488 SoxY_true_GGCGG: thiosulfate oxidation carrier protein SoxY 2 150 2.8E-41 T 12-10-2018 IPR016568 Sulphur oxidation, SoxY TSC_c21110 35c124e719e74de1e1f047a0a46d568f 150 Pfam PF13501 Sulfur oxidation protein SoxY 51 149 1.2E-29 T 12-10-2018 IPR032711 Ig-like SoxY domain TSC_c21110 35c124e719e74de1e1f047a0a46d568f 150 Gene3D G3DSA:2.60.40.2470 23 150 6.0E-46 T 12-10-2018 IPR038162 Ig-like SoxY domain superfamily TSC_c03540 2b2008e9f02a288155804c2141d62382 68 Gene3D G3DSA:3.30.160.250 1 68 1.2E-28 T 12-10-2018 TSC_c03540 2b2008e9f02a288155804c2141d62382 68 SUPERFAMILY SSF143100 4 54 7.32E-11 T 12-10-2018 IPR035069 TTHA1013/TTHA0281-like TSC_c07870 cdf0dfd0fff3eddf16155d35c1b8159a 330 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 34 317 8.4E-99 T 12-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TSC_c07870 cdf0dfd0fff3eddf16155d35c1b8159a 330 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 13 316 1.4E-117 T 12-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TSC_c07870 cdf0dfd0fff3eddf16155d35c1b8159a 330 SUPERFAMILY SSF100950 13 319 1.59E-105 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TSC_c07870 cdf0dfd0fff3eddf16155d35c1b8159a 330 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 3 327 39.163 T 12-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TSC_c07870 cdf0dfd0fff3eddf16155d35c1b8159a 330 Pfam PF01008 Initiation factor 2 subunit family 48 317 3.0E-65 T 12-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 TSC_c07870 cdf0dfd0fff3eddf16155d35c1b8159a 330 Gene3D G3DSA:3.40.50.10470 133 328 1.5E-66 T 12-10-2018 TSC_c07870 cdf0dfd0fff3eddf16155d35c1b8159a 330 Gene3D G3DSA:1.20.120.420 6 130 7.9E-31 T 12-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 TSC_c02090 d928d3c12583ce83feb1d39876603865 301 Gene3D G3DSA:3.40.50.300 2 235 1.7E-58 T 12-10-2018 TSC_c02090 d928d3c12583ce83feb1d39876603865 301 SUPERFAMILY SSF52540 3 240 4.35E-59 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c02090 d928d3c12583ce83feb1d39876603865 301 SMART SM00382 30 222 5.9E-13 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c02090 d928d3c12583ce83feb1d39876603865 301 Pfam PF00005 ABC transporter 21 164 6.9E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c04350 87d9398e28dfa956403847ec4fc49648 592 Gene3D G3DSA:1.20.1560.10 5 334 1.5E-7 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSC_c04350 87d9398e28dfa956403847ec4fc49648 592 Pfam PF00005 ABC transporter 366 516 4.7E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c04350 87d9398e28dfa956403847ec4fc49648 592 ProSitePatterns PS00211 ABC transporters family signature. 488 502 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c04350 87d9398e28dfa956403847ec4fc49648 592 SMART SM00382 374 562 1.6E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c04350 87d9398e28dfa956403847ec4fc49648 592 SUPERFAMILY SSF52540 347 586 2.52E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c04350 87d9398e28dfa956403847ec4fc49648 592 SUPERFAMILY SSF90123 16 324 4.58E-19 T 12-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 TSC_c04350 87d9398e28dfa956403847ec4fc49648 592 Gene3D G3DSA:3.40.50.300 342 591 4.3E-79 T 12-10-2018 TSC_c14300 a2676d93a9833715222dcabd4e595f9d 212 PRINTS PR00988 Uridine kinase signature 81 96 5.9E-36 T 12-10-2018 TSC_c14300 a2676d93a9833715222dcabd4e595f9d 212 PRINTS PR00988 Uridine kinase signature 7 24 5.9E-36 T 12-10-2018 TSC_c14300 a2676d93a9833715222dcabd4e595f9d 212 PRINTS PR00988 Uridine kinase signature 137 147 5.9E-36 T 12-10-2018 TSC_c14300 a2676d93a9833715222dcabd4e595f9d 212 PRINTS PR00988 Uridine kinase signature 173 186 5.9E-36 T 12-10-2018 TSC_c14300 a2676d93a9833715222dcabd4e595f9d 212 PRINTS PR00988 Uridine kinase signature 151 162 5.9E-36 T 12-10-2018 TSC_c14300 a2676d93a9833715222dcabd4e595f9d 212 PRINTS PR00988 Uridine kinase signature 36 47 5.9E-36 T 12-10-2018 TSC_c14300 a2676d93a9833715222dcabd4e595f9d 212 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 9 192 2.1E-41 T 12-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 TSC_c14300 a2676d93a9833715222dcabd4e595f9d 212 Hamap MF_00551 Uridine kinase [udk]. 4 207 38.164 T 12-10-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 TSC_c14300 a2676d93a9833715222dcabd4e595f9d 212 TIGRFAM TIGR00235 udk: uridine kinase 5 201 9.4E-77 T 12-10-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 TSC_c14300 a2676d93a9833715222dcabd4e595f9d 212 SUPERFAMILY SSF52540 5 199 6.75E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c14300 a2676d93a9833715222dcabd4e595f9d 212 Gene3D G3DSA:3.40.50.300 3 212 1.1E-71 T 12-10-2018 TSC_c21150 48b74874caba65acf11fe60ca67243fe 203 SUPERFAMILY SSF63999 1 124 9.68E-24 T 12-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TSC_c21150 48b74874caba65acf11fe60ca67243fe 203 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 5 199 2.2E-41 T 12-10-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TSC_c21150 48b74874caba65acf11fe60ca67243fe 203 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 28 123 6.9E-12 T 12-10-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TSC_c21150 48b74874caba65acf11fe60ca67243fe 203 Gene3D G3DSA:3.40.50.10240 4 202 7.6E-35 T 12-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 TSC_c08850 77ba2e971917a1a6d5f20dc66b8eebd7 322 SUPERFAMILY SSF56954 7 320 1.96E-32 T 12-10-2018 TSC_c08850 77ba2e971917a1a6d5f20dc66b8eebd7 322 Gene3D G3DSA:1.20.1600.10 34 218 2.3E-19 T 12-10-2018 TSC_c08850 77ba2e971917a1a6d5f20dc66b8eebd7 322 Gene3D G3DSA:1.20.1600.10 219 321 8.9E-12 T 12-10-2018 TSC_c08850 77ba2e971917a1a6d5f20dc66b8eebd7 322 Pfam PF02321 Outer membrane efflux protein 63 164 3.1E-13 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSC_c08850 77ba2e971917a1a6d5f20dc66b8eebd7 322 Pfam PF02321 Outer membrane efflux protein 218 319 2.1E-10 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSC_c01620 2c1f6b4c79bfb0e877653a5bf0d69c9f 204 Pfam PF00174 Oxidoreductase molybdopterin binding domain 23 166 1.2E-35 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 TSC_c01620 2c1f6b4c79bfb0e877653a5bf0d69c9f 204 SUPERFAMILY SSF56524 3 184 5.76E-61 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TSC_c01620 2c1f6b4c79bfb0e877653a5bf0d69c9f 204 Gene3D G3DSA:3.90.420.10 11 199 1.6E-48 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TSC_c09610 a1654e117782bcc65571a28ea0bbf714 107 Pfam PF01699 Sodium/calcium exchanger protein 31 67 2.9E-7 T 12-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 TSC_c09610 a1654e117782bcc65571a28ea0bbf714 107 Gene3D G3DSA:1.20.1420.30 29 106 5.1E-8 T 12-10-2018 TSC_c23010 3d2ecf956fadc868f7b23584361a5a0b 238 SMART SM00363 4 64 2.5E-12 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c23010 3d2ecf956fadc868f7b23584361a5a0b 238 SUPERFAMILY SSF55120 50 234 5.04E-40 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c23010 3d2ecf956fadc868f7b23584361a5a0b 238 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 68 221 1.5E-41 T 12-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 TSC_c23010 3d2ecf956fadc868f7b23584361a5a0b 238 SUPERFAMILY SSF55174 5 58 3.34E-13 T 12-10-2018 TSC_c23010 3d2ecf956fadc868f7b23584361a5a0b 238 Gene3D G3DSA:3.30.70.580 65 224 2.3E-52 T 12-10-2018 TSC_c23010 3d2ecf956fadc868f7b23584361a5a0b 238 Gene3D G3DSA:3.30.70.1560 128 208 2.3E-52 T 12-10-2018 TSC_c23010 3d2ecf956fadc868f7b23584361a5a0b 238 Pfam PF01479 S4 domain 4 49 6.8E-14 T 12-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c23010 3d2ecf956fadc868f7b23584361a5a0b 238 Pfam PF00849 RNA pseudouridylate synthase 63 191 9.1E-19 T 12-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c23010 3d2ecf956fadc868f7b23584361a5a0b 238 Gene3D G3DSA:3.10.290.10 3 64 3.7E-17 T 12-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 TSC_c23010 3d2ecf956fadc868f7b23584361a5a0b 238 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 12-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 TSC_c22130 f0d26190e92747df0fdd96c318279c7a 174 SMART SM00507 77 128 1.9E-16 T 12-10-2018 IPR003615 HNH nuclease TSC_c22130 f0d26190e92747df0fdd96c318279c7a 174 Pfam PF14279 HNH endonuclease 90 142 8.4E-17 T 12-10-2018 IPR029471 HNH endonuclease 5 TSC_c22130 f0d26190e92747df0fdd96c318279c7a 174 Gene3D G3DSA:3.30.40.60 64 156 1.4E-24 T 12-10-2018 TSC_c14940 4f5b144acc42bc60140a89ff729d59d8 672 Pfam PF02272 DHHA1 domain 303 417 7.5E-12 T 12-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 TSC_c14940 4f5b144acc42bc60140a89ff729d59d8 672 Gene3D G3DSA:3.90.1640.30 47 307 4.2E-242 T 12-10-2018 TSC_c14940 4f5b144acc42bc60140a89ff729d59d8 672 Gene3D G3DSA:1.20.120.1040 538 667 1.1E-47 T 12-10-2018 TSC_c14940 4f5b144acc42bc60140a89ff729d59d8 672 Gene3D G3DSA:2.40.50.460 1 537 4.2E-242 T 12-10-2018 TSC_c14940 4f5b144acc42bc60140a89ff729d59d8 672 Pfam PF01368 DHH family 75 175 9.7E-10 T 12-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 TSC_c14940 4f5b144acc42bc60140a89ff729d59d8 672 SUPERFAMILY SSF64182 53 425 6.8E-105 T 12-10-2018 IPR038763 DHH phosphoesterase superfamily TSC_c14940 4f5b144acc42bc60140a89ff729d59d8 672 Gene3D G3DSA:3.10.310.30 308 423 4.2E-242 T 12-10-2018 TSC_c17690 c6efeba43c0a61d229e3f1aebc9b0083 125 Gene3D G3DSA:1.20.210.10 3 119 3.0E-7 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c17690 c6efeba43c0a61d229e3f1aebc9b0083 125 SUPERFAMILY SSF81442 7 122 2.22E-6 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c20750 384d261555403337976e01257c8c94a6 455 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 2 91 2.2E-32 T 12-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 TSC_c20750 384d261555403337976e01257c8c94a6 455 Gene3D G3DSA:2.30.130.60 394 455 4.8E-31 T 12-10-2018 TSC_c20750 384d261555403337976e01257c8c94a6 455 Gene3D G3DSA:3.40.50.150 91 393 1.6E-100 T 12-10-2018 TSC_c20750 384d261555403337976e01257c8c94a6 455 Gene3D G3DSA:3.30.70.3130 1 90 6.4E-35 T 12-10-2018 TSC_c20750 384d261555403337976e01257c8c94a6 455 Pfam PF17126 RsmF rRNA methyltransferase first C-terminal domain 325 384 5.3E-17 T 12-10-2018 IPR031340 Ribosomal RNA small subunit methyltransferase F, first C-terminal domain TSC_c20750 384d261555403337976e01257c8c94a6 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 172 184 9.9E-27 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSC_c20750 384d261555403337976e01257c8c94a6 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 77 91 9.9E-27 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSC_c20750 384d261555403337976e01257c8c94a6 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 106 116 9.9E-27 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSC_c20750 384d261555403337976e01257c8c94a6 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 222 238 9.9E-27 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSC_c20750 384d261555403337976e01257c8c94a6 455 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 282 299 9.9E-27 T 12-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase TSC_c20750 384d261555403337976e01257c8c94a6 455 SUPERFAMILY SSF53335 3 299 1.52E-64 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c20750 384d261555403337976e01257c8c94a6 455 Pfam PF01189 16S rRNA methyltransferase RsmB/F 96 298 2.1E-45 T 12-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 TSC_c05380 9b68c4bbea18ae7b766bcea11160e9da 406 SUPERFAMILY SSF82544 3 405 1.11E-115 T 12-10-2018 TSC_c05380 9b68c4bbea18ae7b766bcea11160e9da 406 Gene3D G3DSA:3.40.1480.10 245 401 2.4E-116 T 12-10-2018 IPR037035 Glycerate kinase-like, C-terminal domain superfamily TSC_c05380 9b68c4bbea18ae7b766bcea11160e9da 406 Pfam PF05161 MOFRL family 301 399 6.2E-31 T 12-10-2018 IPR007835 MOFRL domain Reactome: R-HSA-70350 TSC_c05380 9b68c4bbea18ae7b766bcea11160e9da 406 Pfam PF13660 Domain of unknown function (DUF4147) 6 215 3.4E-59 T 12-10-2018 IPR025286 MOFRL-associated domain Reactome: R-HSA-70350 TSC_c05380 9b68c4bbea18ae7b766bcea11160e9da 406 Gene3D G3DSA:3.40.50.10180 30 244 2.4E-116 T 12-10-2018 IPR038614 Glycerate kinase, N-terminal domain superfamily Reactome: R-HSA-70350 TSC_c00490 c68eb078488c5d9d1d845520b09f73c0 169 Pfam PF02597 ThiS family 4 88 3.2E-13 T 12-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 TSC_c00490 c68eb078488c5d9d1d845520b09f73c0 169 Pfam PF09189 Domain of unknown function (DUF1952) 94 166 2.1E-30 T 12-10-2018 IPR015272 Molybdopterin cofactor biosynthesis MoaD-related, C-terminal TSC_c00490 c68eb078488c5d9d1d845520b09f73c0 169 SUPERFAMILY SSF54285 3 88 7.48E-20 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TSC_c00490 c68eb078488c5d9d1d845520b09f73c0 169 Gene3D G3DSA:3.30.1370.80 87 169 1.6E-35 T 12-10-2018 IPR036473 Molybdopterin cofactor biosynthesis MoaD-related, C-terminal domain superfamily TSC_c00490 c68eb078488c5d9d1d845520b09f73c0 169 Gene3D G3DSA:3.10.20.30 2 86 2.6E-28 T 12-10-2018 IPR012675 Beta-grasp domain superfamily TSC_c00490 c68eb078488c5d9d1d845520b09f73c0 169 SUPERFAMILY SSF103239 90 166 5.62E-31 T 12-10-2018 IPR036473 Molybdopterin cofactor biosynthesis MoaD-related, C-terminal domain superfamily TSC_c00490 c68eb078488c5d9d1d845520b09f73c0 169 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 88 1.8E-18 T 12-10-2018 IPR010038 MoaD, archaeal-type TSC_c06520 5237907ea598193ca3783a880b1e9a2d 160 Gene3D G3DSA:3.90.79.10 12 149 2.6E-30 T 12-10-2018 TSC_c06520 5237907ea598193ca3783a880b1e9a2d 160 ProSitePatterns PS00893 Nudix box signature. 45 66 - T 12-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 TSC_c06520 5237907ea598193ca3783a880b1e9a2d 160 Pfam PF00293 NUDIX domain 14 139 1.3E-17 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSC_c06520 5237907ea598193ca3783a880b1e9a2d 160 SUPERFAMILY SSF55811 6 148 9.88E-27 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSC_c20400 84f3e78849b761102b6486740b064d83 377 Gene3D G3DSA:1.20.1530.20 5 359 3.3E-41 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily TSC_c20400 84f3e78849b761102b6486740b064d83 377 Pfam PF00999 Sodium/hydrogen exchanger family 14 347 1.0E-31 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TSC_c05980 196aaeefde9a4591d0458e097a15bc4a 372 Pfam PF00146 NADH dehydrogenase 15 324 1.5E-117 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05980 196aaeefde9a4591d0458e097a15bc4a 372 ProSitePatterns PS00667 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. 54 69 - T 12-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05980 196aaeefde9a4591d0458e097a15bc4a 372 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 217 230 - T 12-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05980 196aaeefde9a4591d0458e097a15bc4a 372 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 8 330 23.797 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c02040 95c1fc7f625b72e1da26c26eabd6612e 359 Pfam PF01478 Type IV leader peptidase family 102 200 3.2E-9 T 12-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 TSC_c02040 95c1fc7f625b72e1da26c26eabd6612e 359 Pfam PF01478 Type IV leader peptidase family 222 322 1.8E-11 T 12-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 TSC_c02040 95c1fc7f625b72e1da26c26eabd6612e 359 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 8 89 1.6E-36 T 12-10-2018 IPR010627 Peptidase A24A, N-terminal TSC_c19100 68407e1c8e42629b80b46e630e8c166b 268 Pfam PF00950 ABC 3 transport family 7 260 4.8E-64 T 12-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 TSC_c19100 68407e1c8e42629b80b46e630e8c166b 268 SUPERFAMILY SSF81345 6 257 8.89E-30 T 12-10-2018 IPR037294 ABC transporter, BtuC-like TSC_c14360 94d8422e6d20effb52ca7d7fd794c676 302 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 4 297 28.198 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TSC_c14360 94d8422e6d20effb52ca7d7fd794c676 302 Gene3D G3DSA:1.10.20.140 111 179 1.3E-84 T 12-10-2018 TSC_c14360 94d8422e6d20effb52ca7d7fd794c676 302 Gene3D G3DSA:3.40.50.300 8 275 1.3E-84 T 12-10-2018 TSC_c14360 94d8422e6d20effb52ca7d7fd794c676 302 SUPERFAMILY SSF52540 6 150 1.17E-16 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c14360 94d8422e6d20effb52ca7d7fd794c676 302 Pfam PF01715 IPP transferase 37 275 1.7E-69 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TSC_c14360 94d8422e6d20effb52ca7d7fd794c676 302 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 6 280 1.4E-71 T 12-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 TSC_c01900 4516c3b46be2a45df054cc9072d65147 105 Gene3D G3DSA:2.20.28.30 60 94 3.3E-6 T 12-10-2018 TSC_c01900 4516c3b46be2a45df054cc9072d65147 105 Gene3D G3DSA:2.20.28.160 5 59 2.3E-12 T 12-10-2018 TSC_c01900 4516c3b46be2a45df054cc9072d65147 105 SUPERFAMILY SSF144217 39 100 1.83E-5 T 12-10-2018 IPR036671 DPH Zinc finger superfamily TSC_c00130 751460a843f6d07cf1490079225ca73a 272 Pfam PF00809 Pterin binding enzyme 17 255 1.8E-81 T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c00130 751460a843f6d07cf1490079225ca73a 272 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 16 31 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c00130 751460a843f6d07cf1490079225ca73a 272 Gene3D G3DSA:3.20.20.20 1 272 6.3E-114 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c00130 751460a843f6d07cf1490079225ca73a 272 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 50 63 - T 12-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c00130 751460a843f6d07cf1490079225ca73a 272 SUPERFAMILY SSF51717 5 272 2.09E-97 T 12-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 TSC_c00130 751460a843f6d07cf1490079225ca73a 272 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 16 270 1.1E-94 T 12-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 TSC_c12180 3656e937b3e903748d0ec4bf9dd43d63 151 Gene3D G3DSA:3.30.300.130 1 95 1.5E-24 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSC_c12180 3656e937b3e903748d0ec4bf9dd43d63 151 Pfam PF01883 Iron-sulfur cluster assembly protein 6 73 4.9E-17 T 12-10-2018 IPR002744 MIP18 family-like TSC_c12180 3656e937b3e903748d0ec4bf9dd43d63 151 SUPERFAMILY SSF117916 3 93 2.62E-20 T 12-10-2018 IPR034904 Fe-S cluster assembly domain superfamily TSC_c12180 3656e937b3e903748d0ec4bf9dd43d63 151 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 12 151 6.6E-46 T 12-10-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit TSC_c10160 eaa2285060364d31e362517ab62f9112 287 Gene3D G3DSA:3.40.1360.10 186 287 1.8E-10 T 12-10-2018 TSC_c10160 eaa2285060364d31e362517ab62f9112 287 SUPERFAMILY SSF56731 175 282 8.89E-7 T 12-10-2018 TSC_c10160 eaa2285060364d31e362517ab62f9112 287 Pfam PF13362 Toprim domain 197 284 3.9E-21 T 12-10-2018 IPR006171 TOPRIM domain TSC_c24580 8170b2dbabba7a16131bfe4398c722fe 149 Pfam PF00588 SpoU rRNA Methylase family 2 140 2.0E-33 T 12-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 TSC_c24580 8170b2dbabba7a16131bfe4398c722fe 149 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 149 33.365 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 TSC_c24580 8170b2dbabba7a16131bfe4398c722fe 149 Gene3D G3DSA:3.40.1280.10 1 149 4.0E-60 T 12-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal TSC_c24580 8170b2dbabba7a16131bfe4398c722fe 149 SUPERFAMILY SSF75217 1 147 2.03E-42 T 12-10-2018 IPR029028 Alpha/beta knot methyltransferases TSC_c24580 8170b2dbabba7a16131bfe4398c722fe 149 PIRSF PIRSF029256 1 149 4.4E-55 T 12-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 TSC_c18920 1dcb3f41094ec6d0ee7a47f3b95fd201 433 Gene3D G3DSA:3.30.870.10 183 323 1.7E-27 T 12-10-2018 TSC_c18920 1dcb3f41094ec6d0ee7a47f3b95fd201 433 SMART SM00155 106 133 0.029 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 TSC_c18920 1dcb3f41094ec6d0ee7a47f3b95fd201 433 SMART SM00155 262 289 0.0024 T 12-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 TSC_c18920 1dcb3f41094ec6d0ee7a47f3b95fd201 433 SUPERFAMILY SSF56024 177 326 1.82E-25 T 12-10-2018 TSC_c18920 1dcb3f41094ec6d0ee7a47f3b95fd201 433 Gene3D G3DSA:3.30.870.10 16 163 1.3E-33 T 12-10-2018 TSC_c18920 1dcb3f41094ec6d0ee7a47f3b95fd201 433 Pfam PF13091 PLD-like domain 193 311 6.3E-20 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 TSC_c18920 1dcb3f41094ec6d0ee7a47f3b95fd201 433 Pfam PF13091 PLD-like domain 32 161 2.1E-22 T 12-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 TSC_c18920 1dcb3f41094ec6d0ee7a47f3b95fd201 433 SUPERFAMILY SSF56024 20 162 1.01E-31 T 12-10-2018 TSC_c21360 92496c697f3633b2f2c05c4bd0a460b4 115 SMART SM00960 1 90 3.3E-16 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain TSC_c21360 92496c697f3633b2f2c05c4bd0a460b4 115 Gene3D G3DSA:3.30.450.30 1 115 2.4E-22 T 12-10-2018 TSC_c21360 92496c697f3633b2f2c05c4bd0a460b4 115 SUPERFAMILY SSF103196 2 114 5.58E-22 T 12-10-2018 TSC_c21360 92496c697f3633b2f2c05c4bd0a460b4 115 Pfam PF03259 Roadblock/LC7 domain 2 88 1.6E-13 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain TSC_c10030 2bf5d46fcd27b1cc307dd1420df81675 992 Gene3D G3DSA:3.30.200.210 34 132 2.3E-20 T 12-10-2018 TSC_c10030 2bf5d46fcd27b1cc307dd1420df81675 992 Gene3D G3DSA:2.40.40.20 819 992 1.5E-68 T 12-10-2018 TSC_c10030 2bf5d46fcd27b1cc307dd1420df81675 992 Gene3D G3DSA:3.40.228.10 179 472 4.2E-90 T 12-10-2018 TSC_c10030 2bf5d46fcd27b1cc307dd1420df81675 992 Gene3D G3DSA:3.40.50.740 520 674 1.5E-62 T 12-10-2018 TSC_c10030 2bf5d46fcd27b1cc307dd1420df81675 992 SMART SM00926 37 91 5.1E-19 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c10030 2bf5d46fcd27b1cc307dd1420df81675 992 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 4 991 0.0 T 12-10-2018 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 TSC_c10030 2bf5d46fcd27b1cc307dd1420df81675 992 Pfam PF00384 Molybdopterin oxidoreductase 146 650 1.7E-37 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c10030 2bf5d46fcd27b1cc307dd1420df81675 992 SUPERFAMILY SSF53706 41 828 4.32E-297 T 12-10-2018 TSC_c10030 2bf5d46fcd27b1cc307dd1420df81675 992 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 43 90 3.0E-16 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c10030 2bf5d46fcd27b1cc307dd1420df81675 992 Pfam PF01568 Molydopterin dinucleotide binding domain 868 984 3.0E-19 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSC_c10030 2bf5d46fcd27b1cc307dd1420df81675 992 SUPERFAMILY SSF50692 808 992 9.12E-49 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSC_c10030 2bf5d46fcd27b1cc307dd1420df81675 992 Gene3D G3DSA:3.40.228.10 740 818 1.0E-19 T 12-10-2018 TSC_c18170 e3d6af4106a911f6adb8e739e48076af 95 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 41 2.0E-6 T 12-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 TSC_c03630 20dbaf0835041e637dc36fbd109dff24 404 Gene3D G3DSA:3.40.50.200 96 395 3.4E-87 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TSC_c03630 20dbaf0835041e637dc36fbd109dff24 404 Pfam PF00082 Subtilase family 128 383 2.8E-55 T 12-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 TSC_c03630 20dbaf0835041e637dc36fbd109dff24 404 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 173 183 - T 12-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site TSC_c03630 20dbaf0835041e637dc36fbd109dff24 404 SUPERFAMILY SSF52743 109 388 9.56E-78 T 12-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 TSC_c03630 20dbaf0835041e637dc36fbd109dff24 404 PRINTS PR00723 Subtilisin serine protease family (S8) signature 128 147 9.9E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TSC_c03630 20dbaf0835041e637dc36fbd109dff24 404 PRINTS PR00723 Subtilisin serine protease family (S8) signature 169 182 9.9E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TSC_c03630 20dbaf0835041e637dc36fbd109dff24 404 PRINTS PR00723 Subtilisin serine protease family (S8) signature 344 360 9.9E-22 T 12-10-2018 IPR015500 Peptidase S8, subtilisin-related TSC_c03630 20dbaf0835041e637dc36fbd109dff24 404 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 345 355 - T 12-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site TSC_c03630 20dbaf0835041e637dc36fbd109dff24 404 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 133 144 - T 12-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site TSC_c01520 d4991d2de6c08caa4de8dd1e04004055 333 Pfam PF00586 AIR synthase related protein, N-terminal domain 45 160 2.6E-15 T 12-10-2018 IPR016188 PurM-like, N-terminal domain TSC_c01520 d4991d2de6c08caa4de8dd1e04004055 333 Pfam PF02769 AIR synthase related protein, C-terminal domain 172 331 4.3E-25 T 12-10-2018 IPR010918 PurM-like, C-terminal domain TSC_c01520 d4991d2de6c08caa4de8dd1e04004055 333 SUPERFAMILY SSF55326 2 165 1.94E-41 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSC_c01520 d4991d2de6c08caa4de8dd1e04004055 333 Gene3D G3DSA:3.90.650.10 167 333 6.3E-66 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSC_c01520 d4991d2de6c08caa4de8dd1e04004055 333 Gene3D G3DSA:3.30.1330.10 1 166 3.3E-56 T 12-10-2018 IPR036921 PurM-like, N-terminal domain superfamily TSC_c01520 d4991d2de6c08caa4de8dd1e04004055 333 SUPERFAMILY SSF56042 168 331 2.27E-51 T 12-10-2018 IPR036676 PurM-like, C-terminal domain superfamily TSC_c01520 d4991d2de6c08caa4de8dd1e04004055 333 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 2 325 5.3E-105 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSC_c01520 d4991d2de6c08caa4de8dd1e04004055 333 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 1 333 39.103 T 12-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 TSC_c14860 b42efca3924ec5da6ccb042aa6d30a13 297 Pfam PF03547 Membrane transport protein 5 135 3.6E-11 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 TSC_c14860 b42efca3924ec5da6ccb042aa6d30a13 297 Pfam PF03547 Membrane transport protein 155 290 3.6E-17 T 12-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 TSC_c05960 0cd6b200c9a2930f1147d2d04a88b3ac 179 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 16 156 5.8E-28 T 12-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05960 0cd6b200c9a2930f1147d2d04a88b3ac 179 Gene3D G3DSA:1.20.120.1200 2 160 9.1E-48 T 12-10-2018 TSC_c07500 c899649004073888e6853adeee01b9ab 267 PIRSF PIRSF003092 1 267 3.5E-89 T 12-10-2018 IPR025501 ATP binding protein MinD TSC_c07500 c899649004073888e6853adeee01b9ab 267 Gene3D G3DSA:3.40.50.300 3 255 2.8E-67 T 12-10-2018 TSC_c07500 c899649004073888e6853adeee01b9ab 267 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 6 221 2.3E-22 T 12-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain TSC_c07500 c899649004073888e6853adeee01b9ab 267 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 264 1.8E-118 T 12-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 TSC_c07500 c899649004073888e6853adeee01b9ab 267 SUPERFAMILY SSF52540 3 248 6.08E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c04160 76e5dcc70fbd81fc385dabf65c031424 576 Hamap MF_00335 Ribonuclease Y [rny]. 3 576 24.654 T 12-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 TSC_c04160 76e5dcc70fbd81fc385dabf65c031424 576 SUPERFAMILY SSF54791 269 359 4.56E-15 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TSC_c04160 76e5dcc70fbd81fc385dabf65c031424 576 Pfam PF01966 HD domain 393 484 3.1E-17 T 12-10-2018 IPR006674 HD domain TSC_c04160 76e5dcc70fbd81fc385dabf65c031424 576 SMART SM00471 388 494 3.9E-13 T 12-10-2018 IPR003607 HD/PDEase domain TSC_c04160 76e5dcc70fbd81fc385dabf65c031424 576 SUPERFAMILY SSF109604 381 504 6.73E-28 T 12-10-2018 TSC_c04160 76e5dcc70fbd81fc385dabf65c031424 576 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 123 576 5.0E-192 T 12-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 TSC_c04160 76e5dcc70fbd81fc385dabf65c031424 576 Pfam PF00013 KH domain 269 326 2.9E-6 T 12-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 TSC_c04160 76e5dcc70fbd81fc385dabf65c031424 576 TIGRFAM TIGR00277 HDIG: HDIG domain 388 463 1.7E-23 T 12-10-2018 IPR006675 HDIG domain TSC_c04160 76e5dcc70fbd81fc385dabf65c031424 576 Gene3D G3DSA:3.30.1370.10 269 358 6.8E-9 T 12-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 TSC_c04160 76e5dcc70fbd81fc385dabf65c031424 576 Gene3D G3DSA:1.10.3210.10 374 528 3.6E-24 T 12-10-2018 TSC_c04160 76e5dcc70fbd81fc385dabf65c031424 576 Pfam PF12072 Domain of unknown function (DUF3552) 136 260 6.8E-17 T 12-10-2018 IPR022711 Ribonuclease Y, N-terminal TSC_c04160 76e5dcc70fbd81fc385dabf65c031424 576 SMART SM00322 264 331 2.5E-7 T 12-10-2018 IPR004087 K Homology domain GO:0003676 TSC_c11600 6ee78a4aa562312ee8a20f52bf5700fe 502 SUPERFAMILY SSF53720 21 500 3.14E-166 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSC_c11600 6ee78a4aa562312ee8a20f52bf5700fe 502 Gene3D G3DSA:3.40.309.10 273 470 2.2E-173 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSC_c11600 6ee78a4aa562312ee8a20f52bf5700fe 502 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 269 276 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TSC_c11600 6ee78a4aa562312ee8a20f52bf5700fe 502 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 297 308 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TSC_c11600 6ee78a4aa562312ee8a20f52bf5700fe 502 Pfam PF00171 Aldehyde dehydrogenase family 38 497 1.7E-166 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSC_c11600 6ee78a4aa562312ee8a20f52bf5700fe 502 Gene3D G3DSA:3.40.605.10 40 495 2.2E-173 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSC_c04470 0f04d577af335a731376bfadc2318093 770 Gene3D G3DSA:2.30.120.10 323 391 6.2E-173 T 12-10-2018 TSC_c04470 0f04d577af335a731376bfadc2318093 770 Gene3D G3DSA:3.60.20.10 251 748 6.2E-173 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSC_c04470 0f04d577af335a731376bfadc2318093 770 Gene3D G3DSA:1.10.439.10 22 182 3.2E-59 T 12-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 TSC_c04470 0f04d577af335a731376bfadc2318093 770 PIRSF PIRSF001227 9 763 1.5E-191 T 12-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 TSC_c04470 0f04d577af335a731376bfadc2318093 770 SUPERFAMILY SSF56235 45 757 2.83E-222 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSC_c04470 0f04d577af335a731376bfadc2318093 770 Pfam PF01804 Penicillin amidase 49 757 2.3E-225 T 12-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 TSC_c04470 0f04d577af335a731376bfadc2318093 770 Gene3D G3DSA:1.10.1400.10 541 660 6.2E-173 T 12-10-2018 TSC_c19030 b0ed98c297ee96df71818687fbfe2b11 307 Pfam PF00005 ABC transporter 20 162 5.9E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c19030 b0ed98c297ee96df71818687fbfe2b11 307 SMART SM00382 28 226 1.3E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c19030 b0ed98c297ee96df71818687fbfe2b11 307 SUPERFAMILY SSF52540 3 224 4.99E-63 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c19030 b0ed98c297ee96df71818687fbfe2b11 307 Gene3D G3DSA:3.40.50.300 1 227 4.0E-67 T 12-10-2018 TSC_c21950 ae39e2591e8bbd1b3a30b8c1e759d1cb 147 SUPERFAMILY SSF46767 68 144 1.01E-20 T 12-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 TSC_c21950 ae39e2591e8bbd1b3a30b8c1e759d1cb 147 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 72 144 3.2E-21 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TSC_c21950 ae39e2591e8bbd1b3a30b8c1e759d1cb 147 Gene3D G3DSA:1.10.10.10 66 146 5.9E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c21950 ae39e2591e8bbd1b3a30b8c1e759d1cb 147 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 71 143 1.1E-18 T 12-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 TSC_c09080 5576ee8149532df4e6d639998a5bae44 243 SUPERFAMILY SSF53474 2 240 2.2E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c09080 5576ee8149532df4e6d639998a5bae44 243 Pfam PF12697 Alpha/beta hydrolase family 13 230 1.1E-24 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSC_c09080 5576ee8149532df4e6d639998a5bae44 243 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 94 1.4E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSC_c09080 5576ee8149532df4e6d639998a5bae44 243 PRINTS PR00111 Alpha/beta hydrolase fold signature 184 198 1.4E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSC_c09080 5576ee8149532df4e6d639998a5bae44 243 PRINTS PR00111 Alpha/beta hydrolase fold signature 36 51 1.4E-10 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSC_c09080 5576ee8149532df4e6d639998a5bae44 243 Gene3D G3DSA:3.40.50.1820 1 241 6.2E-50 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c20390 73254881390391df92049c649bcb107a 157 PIRSF PIRSF005028 1 157 2.0E-50 T 12-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT TSC_c20390 73254881390391df92049c649bcb107a 157 Gene3D G3DSA:3.30.70.1450 84 157 2.5E-16 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSC_c20390 73254881390391df92049c649bcb107a 157 Pfam PF02080 TrkA-C domain 90 155 1.6E-15 T 12-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 TSC_c20390 73254881390391df92049c649bcb107a 157 SUPERFAMILY SSF116726 85 156 2.88E-16 T 12-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 TSC_c13950 2ee3e81c38f70c3aa494379a1da7b2b7 861 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 242 257 1.1E-52 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSC_c13950 2ee3e81c38f70c3aa494379a1da7b2b7 861 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 370 390 1.1E-52 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSC_c13950 2ee3e81c38f70c3aa494379a1da7b2b7 861 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 184 200 1.1E-52 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSC_c13950 2ee3e81c38f70c3aa494379a1da7b2b7 861 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 523 543 1.1E-52 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSC_c13950 2ee3e81c38f70c3aa494379a1da7b2b7 861 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 565 594 1.1E-52 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSC_c13950 2ee3e81c38f70c3aa494379a1da7b2b7 861 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 697 723 1.1E-52 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSC_c13950 2ee3e81c38f70c3aa494379a1da7b2b7 861 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 143 156 1.1E-52 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSC_c13950 2ee3e81c38f70c3aa494379a1da7b2b7 861 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 525 537 - T 12-10-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSC_c13950 2ee3e81c38f70c3aa494379a1da7b2b7 861 Pfam PF00311 Phosphoenolpyruvate carboxylase 139 861 3.8E-200 T 12-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSC_c13950 2ee3e81c38f70c3aa494379a1da7b2b7 861 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 144 155 - T 12-10-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSC_c13950 2ee3e81c38f70c3aa494379a1da7b2b7 861 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 5 861 16.737 T 12-10-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 TSC_c13950 2ee3e81c38f70c3aa494379a1da7b2b7 861 SUPERFAMILY SSF51621 14 861 1.07E-240 T 12-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 TSC_c06670 f105ecf62b0e39e6538043409f14065c 59 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 6 51 2.8E-18 T 12-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 TSC_c06670 f105ecf62b0e39e6538043409f14065c 59 SUPERFAMILY SSF46955 5 52 2.93E-6 T 12-10-2018 IPR009061 Putative DNA-binding domain superfamily TSC_c06670 f105ecf62b0e39e6538043409f14065c 59 Pfam PF12728 Helix-turn-helix domain 5 52 5.8E-18 T 12-10-2018 TSC_c06670 f105ecf62b0e39e6538043409f14065c 59 Gene3D G3DSA:1.10.1660.10 2 53 1.6E-11 T 12-10-2018 TSC_c07430 13e35e2020c267bf69a89751458330c1 625 Pfam PF13193 AMP-binding enzyme C-terminal domain 525 602 8.7E-31 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSC_c07430 13e35e2020c267bf69a89751458330c1 625 ProSitePatterns PS00455 Putative AMP-binding domain signature. 253 264 - T 12-10-2018 IPR020845 AMP-binding, conserved site TSC_c07430 13e35e2020c267bf69a89751458330c1 625 SUPERFAMILY SSF56801 23 615 1.57E-167 T 12-10-2018 TSC_c07430 13e35e2020c267bf69a89751458330c1 625 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 28 79 8.8E-20 T 12-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 TSC_c07430 13e35e2020c267bf69a89751458330c1 625 Gene3D G3DSA:3.40.50.12780 51 509 8.2E-103 T 12-10-2018 TSC_c07430 13e35e2020c267bf69a89751458330c1 625 Pfam PF00501 AMP-binding enzyme 82 515 3.1E-88 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSC_c07430 13e35e2020c267bf69a89751458330c1 625 Gene3D G3DSA:3.30.300.30 511 624 1.1E-30 T 12-10-2018 TSC_c19970 6beb38082625d37a6bf0e15a49698c4c 222 PIRSF PIRSF001461 1 220 5.4E-89 T 12-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TSC_c19970 6beb38082625d37a6bf0e15a49698c4c 222 Pfam PF00834 Ribulose-phosphate 3 epimerase family 4 200 3.5E-80 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TSC_c19970 6beb38082625d37a6bf0e15a49698c4c 222 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TSC_c19970 6beb38082625d37a6bf0e15a49698c4c 222 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 4 213 6.0E-88 T 12-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 TSC_c19970 6beb38082625d37a6bf0e15a49698c4c 222 SUPERFAMILY SSF51366 1 215 2.51E-70 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSC_c19970 6beb38082625d37a6bf0e15a49698c4c 222 Gene3D G3DSA:3.20.20.70 1 218 3.1E-82 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c17920 b12ae45b92031bb81e082cdb3fb8f638 259 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 13 259 34.818 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TSC_c17920 b12ae45b92031bb81e082cdb3fb8f638 259 Gene3D G3DSA:3.20.20.70 1 258 3.6E-96 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c17920 b12ae45b92031bb81e082cdb3fb8f638 259 SUPERFAMILY SSF51366 4 239 1.65E-75 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSC_c17920 b12ae45b92031bb81e082cdb3fb8f638 259 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 46 59 - T 12-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TSC_c17920 b12ae45b92031bb81e082cdb3fb8f638 259 Pfam PF00290 Tryptophan synthase alpha chain 7 237 1.2E-89 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TSC_c17920 b12ae45b92031bb81e082cdb3fb8f638 259 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 7 239 1.0E-70 T 12-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 TSC_c08170 94bcacd88cd9b8063b883a6d8112e68a 352 SUPERFAMILY SSF116734 124 339 3.11E-39 T 12-10-2018 TSC_c08170 94bcacd88cd9b8063b883a6d8112e68a 352 Pfam PF01420 Type I restriction modification DNA specificity domain 135 312 2.0E-11 T 12-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 TSC_c08170 94bcacd88cd9b8063b883a6d8112e68a 352 Gene3D G3DSA:1.10.287.1120 67 331 1.3E-56 T 12-10-2018 TSC_c08170 94bcacd88cd9b8063b883a6d8112e68a 352 Gene3D G3DSA:3.90.220.20 137 288 1.3E-56 T 12-10-2018 TSC_c08170 94bcacd88cd9b8063b883a6d8112e68a 352 SUPERFAMILY SSF116734 4 110 7.03E-18 T 12-10-2018 TSC_c08170 94bcacd88cd9b8063b883a6d8112e68a 352 Gene3D G3DSA:3.90.220.20 19 335 1.3E-56 T 12-10-2018 TSC_c11190 3acfd5a6ed4d596f9690bb26e05e0ebd 279 SUPERFAMILY SSF52096 57 239 1.78E-26 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSC_c11190 3acfd5a6ed4d596f9690bb26e05e0ebd 279 Pfam PF01972 Serine dehydrogenase proteinase 4 278 7.7E-121 T 12-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 TSC_c11190 3acfd5a6ed4d596f9690bb26e05e0ebd 279 Gene3D G3DSA:3.90.226.10 57 239 4.6E-22 T 12-10-2018 TSC_c05060 2d36f6e9c865ba096f45a34bf61fd924 259 SUPERFAMILY SSF52540 3 251 1.74E-68 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c05060 2d36f6e9c865ba096f45a34bf61fd924 259 SMART SM00382 28 228 1.5E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c05060 2d36f6e9c865ba096f45a34bf61fd924 259 Gene3D G3DSA:3.40.50.300 1 254 1.3E-66 T 12-10-2018 TSC_c05060 2d36f6e9c865ba096f45a34bf61fd924 259 Pfam PF00005 ABC transporter 20 179 2.3E-31 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c05060 2d36f6e9c865ba096f45a34bf61fd924 259 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 230 251 1.3E-13 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSC_c07350 2c395d706e39fafd7c44f2b93dd6c7f7 119 Gene3D G3DSA:3.40.50.12740 1 119 3.3E-37 T 12-10-2018 TSC_c07350 2c395d706e39fafd7c44f2b93dd6c7f7 119 SUPERFAMILY SSF52172 1 116 3.84E-36 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c07350 2c395d706e39fafd7c44f2b93dd6c7f7 119 Pfam PF00072 Response regulator receiver domain 3 112 6.4E-26 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c07350 2c395d706e39fafd7c44f2b93dd6c7f7 119 SMART SM00448 1 112 5.1E-37 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c17100 4f540e7158e986f46530feaafbeec082 92 Pfam PF01037 Lrp/AsnC ligand binding domain 6 76 8.2E-17 T 12-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain TSC_c17100 4f540e7158e986f46530feaafbeec082 92 Gene3D G3DSA:3.30.70.920 1 74 1.3E-21 T 12-10-2018 TSC_c17100 4f540e7158e986f46530feaafbeec082 92 SUPERFAMILY SSF54909 2 78 2.82E-17 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TSC_c11920 e91b270795753f62b61e742d6192a072 363 Pfam PF01950 Fructose-1,6-bisphosphatase 2 362 1.9E-158 T 12-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TSC_c11920 e91b270795753f62b61e742d6192a072 363 SUPERFAMILY SSF111249 2 362 2.88E-152 T 12-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TSC_c11920 e91b270795753f62b61e742d6192a072 363 PIRSF PIRSF015647 1 363 6.0E-164 T 12-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TSC_c11920 e91b270795753f62b61e742d6192a072 363 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 2 362 0.0 T 12-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TSC_c11920 e91b270795753f62b61e742d6192a072 363 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 1 363 56.774 T 12-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TSC_c17600 6f7a13152138659a0269259b6e4efd33 476 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 16 445 2.7E-71 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c17600 6f7a13152138659a0269259b6e4efd33 476 Gene3D G3DSA:1.20.210.10 1 471 4.5E-120 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c17600 6f7a13152138659a0269259b6e4efd33 476 SUPERFAMILY SSF81442 12 460 1.57E-69 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c17600 6f7a13152138659a0269259b6e4efd33 476 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 203 259 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c12730 b68a9d71653fb12aa6242dc5500d9892 677 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 425 2.0E-80 T 12-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 TSC_c12730 b68a9d71653fb12aa6242dc5500d9892 677 Pfam PF07690 Major Facilitator Superfamily 15 408 1.4E-49 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c12730 b68a9d71653fb12aa6242dc5500d9892 677 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 2.3E-7 T 12-10-2018 TSC_c12730 b68a9d71653fb12aa6242dc5500d9892 677 PRINTS PR01036 Tetracycline resistance protein TetB signature 73 95 2.3E-7 T 12-10-2018 TSC_c12730 b68a9d71653fb12aa6242dc5500d9892 677 PRINTS PR01036 Tetracycline resistance protein TetB signature 299 323 2.3E-7 T 12-10-2018 TSC_c12730 b68a9d71653fb12aa6242dc5500d9892 677 PRINTS PR01036 Tetracycline resistance protein TetB signature 399 418 2.3E-7 T 12-10-2018 TSC_c12730 b68a9d71653fb12aa6242dc5500d9892 677 Gene3D G3DSA:1.20.1250.20 256 435 4.5E-22 T 12-10-2018 TSC_c12730 b68a9d71653fb12aa6242dc5500d9892 677 SUPERFAMILY SSF103473 8 419 4.19E-61 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c12730 b68a9d71653fb12aa6242dc5500d9892 677 Gene3D G3DSA:1.20.1720.10 12 245 2.5E-45 T 12-10-2018 TSC_c11710 fa22b1477dfd7ae7dcb391d5804bd984 202 SUPERFAMILY SSF46458 33 161 9.6E-16 T 12-10-2018 IPR009050 Globin-like superfamily TSC_c11710 fa22b1477dfd7ae7dcb391d5804bd984 202 Gene3D G3DSA:1.10.490.10 32 174 6.1E-24 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TSC_c11710 fa22b1477dfd7ae7dcb391d5804bd984 202 Pfam PF11563 Protoglobin 33 169 2.7E-19 T 12-10-2018 TSC_c19830 9003100da555ae32183810e9098592a4 349 Pfam PF01380 SIS domain 50 170 3.2E-14 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TSC_c19830 9003100da555ae32183810e9098592a4 349 Pfam PF01380 SIS domain 203 312 7.1E-15 T 12-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 TSC_c19830 9003100da555ae32183810e9098592a4 349 SUPERFAMILY SSF53697 10 347 2.23E-69 T 12-10-2018 TSC_c19830 9003100da555ae32183810e9098592a4 349 Gene3D G3DSA:3.40.50.10490 6 196 1.7E-46 T 12-10-2018 TSC_c19830 9003100da555ae32183810e9098592a4 349 Gene3D G3DSA:3.40.50.10490 197 348 1.7E-39 T 12-10-2018 TSC_c00240 558b9a94dadc033ce258b843f165095d 204 Pfam PF00753 Metallo-beta-lactamase superfamily 20 186 4.9E-25 T 12-10-2018 IPR001279 Metallo-beta-lactamase TSC_c00240 558b9a94dadc033ce258b843f165095d 204 SMART SM00849 10 186 3.0E-27 T 12-10-2018 IPR001279 Metallo-beta-lactamase TSC_c00240 558b9a94dadc033ce258b843f165095d 204 Gene3D G3DSA:3.60.15.10 3 200 1.1E-37 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c00240 558b9a94dadc033ce258b843f165095d 204 SUPERFAMILY SSF56281 9 192 1.83E-40 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c18640 cd536e0a3c2207ccc62d78e970e0d510 320 Gene3D G3DSA:3.20.20.140 3 320 2.4E-61 T 12-10-2018 TSC_c18640 cd536e0a3c2207ccc62d78e970e0d510 320 SUPERFAMILY SSF51556 4 318 7.48E-53 T 12-10-2018 IPR032466 Metal-dependent hydrolase TSC_c18640 cd536e0a3c2207ccc62d78e970e0d510 320 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 4 285 3.9E-47 T 12-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 TSC_c04100 dc6d87c0b21dc339ede123d7af2ec703 208 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 68 153 2.8E-6 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c04100 dc6d87c0b21dc339ede123d7af2ec703 208 Gene3D G3DSA:1.10.150.240 17 81 2.2E-52 T 12-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 TSC_c04100 dc6d87c0b21dc339ede123d7af2ec703 208 Gene3D G3DSA:3.40.50.1000 6 195 2.2E-52 T 12-10-2018 IPR023214 HAD superfamily TSC_c04100 dc6d87c0b21dc339ede123d7af2ec703 208 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 162 8.9E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c04100 dc6d87c0b21dc339ede123d7af2ec703 208 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 95 108 8.9E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c04100 dc6d87c0b21dc339ede123d7af2ec703 208 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 8.9E-7 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c04100 dc6d87c0b21dc339ede123d7af2ec703 208 SUPERFAMILY SSF56784 1 208 3.72E-53 T 12-10-2018 IPR036412 HAD-like superfamily TSC_c04100 dc6d87c0b21dc339ede123d7af2ec703 208 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 179 3.2E-29 T 12-10-2018 TSC_c04100 dc6d87c0b21dc339ede123d7af2ec703 208 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 27 178 5.9E-20 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c01390 eccd902990ccfe797c73816842313573 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 280 4.7E-20 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c01390 eccd902990ccfe797c73816842313573 291 Gene3D G3DSA:1.10.3720.10 49 288 2.5E-73 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c01390 eccd902990ccfe797c73816842313573 291 SUPERFAMILY SSF161098 53 279 3.66E-64 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c05260 9840a9c87d6e0da407f5c20f0b1ac6dd 363 Pfam PF00571 CBS domain 306 353 2.3E-9 T 12-10-2018 IPR000644 CBS domain TSC_c05260 9840a9c87d6e0da407f5c20f0b1ac6dd 363 Pfam PF00571 CBS domain 243 289 5.5E-11 T 12-10-2018 IPR000644 CBS domain TSC_c05260 9840a9c87d6e0da407f5c20f0b1ac6dd 363 PIRSF PIRSF006404 2 362 1.2E-114 T 12-10-2018 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS TSC_c05260 9840a9c87d6e0da407f5c20f0b1ac6dd 363 SMART SM00116 307 354 3.8E-8 T 12-10-2018 IPR000644 CBS domain TSC_c05260 9840a9c87d6e0da407f5c20f0b1ac6dd 363 SMART SM00116 250 297 3.5E-4 T 12-10-2018 IPR000644 CBS domain TSC_c05260 9840a9c87d6e0da407f5c20f0b1ac6dd 363 SUPERFAMILY SSF54631 238 353 3.66E-27 T 12-10-2018 TSC_c05260 9840a9c87d6e0da407f5c20f0b1ac6dd 363 Pfam PF02163 Peptidase family M50 66 136 2.0E-7 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TSC_c05260 9840a9c87d6e0da407f5c20f0b1ac6dd 363 Pfam PF02163 Peptidase family M50 145 194 3.6E-8 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TSC_c05260 9840a9c87d6e0da407f5c20f0b1ac6dd 363 Gene3D G3DSA:3.10.580.10 297 359 6.3E-10 T 12-10-2018 TSC_c05260 9840a9c87d6e0da407f5c20f0b1ac6dd 363 Gene3D G3DSA:3.10.580.10 209 295 2.5E-12 T 12-10-2018 TSC_c19560 fe794e8f6c565d2de31e4abda91e1dbd 332 SUPERFAMILY SSF51735 1 149 2.63E-22 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c19560 fe794e8f6c565d2de31e4abda91e1dbd 332 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 173 195 - T 12-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TSC_c19560 fe794e8f6c565d2de31e4abda91e1dbd 332 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 115 1.6E-10 T 12-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 TSC_c19560 fe794e8f6c565d2de31e4abda91e1dbd 332 Pfam PF00742 Homoserine dehydrogenase 135 302 1.2E-48 T 12-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TSC_c19560 fe794e8f6c565d2de31e4abda91e1dbd 332 SUPERFAMILY SSF55347 132 290 3.07E-39 T 12-10-2018 TSC_c19560 fe794e8f6c565d2de31e4abda91e1dbd 332 Gene3D G3DSA:3.30.360.10 138 286 5.9E-102 T 12-10-2018 TSC_c19560 fe794e8f6c565d2de31e4abda91e1dbd 332 Gene3D G3DSA:3.40.50.720 4 303 5.9E-102 T 12-10-2018 TSC_c19560 fe794e8f6c565d2de31e4abda91e1dbd 332 PIRSF PIRSF036497 1 310 5.7E-77 T 12-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 TSC_c10560 2e2ca36c22922b89b54e7576d54d260f 637 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 479 637 1.4E-53 T 12-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 TSC_c10560 2e2ca36c22922b89b54e7576d54d260f 637 Gene3D G3DSA:3.40.50.880 245 401 9.2E-16 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c10560 2e2ca36c22922b89b54e7576d54d260f 637 Pfam PF13500 AAA domain 5 226 3.5E-19 T 12-10-2018 TSC_c10560 2e2ca36c22922b89b54e7576d54d260f 637 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 456 114.585 T 12-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 TSC_c10560 2e2ca36c22922b89b54e7576d54d260f 637 Gene3D G3DSA:3.40.50.300 3 232 1.8E-46 T 12-10-2018 TSC_c10560 2e2ca36c22922b89b54e7576d54d260f 637 Gene3D G3DSA:3.40.50.300 478 637 7.6E-49 T 12-10-2018 TSC_c10560 2e2ca36c22922b89b54e7576d54d260f 637 SUPERFAMILY SSF52540 4 234 1.78E-45 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c10560 2e2ca36c22922b89b54e7576d54d260f 637 SUPERFAMILY SSF52317 190 401 5.47E-25 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c10560 2e2ca36c22922b89b54e7576d54d260f 637 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 246 394 5.1E-24 T 12-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 TSC_c10560 2e2ca36c22922b89b54e7576d54d260f 637 SUPERFAMILY SSF52540 478 637 2.42E-42 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c21320 c722f8395732efd7dd760d88065c6eba 105 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 2 94 1.1E-15 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TSC_c21320 c722f8395732efd7dd760d88065c6eba 105 PIRSF PIRSF004555 1 105 2.2E-26 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TSC_c21320 c722f8395732efd7dd760d88065c6eba 105 Gene3D G3DSA:3.30.1310.10 3 105 1.7E-24 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TSC_c21320 c722f8395732efd7dd760d88065c6eba 105 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 1 96 18.441 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TSC_c21320 c722f8395732efd7dd760d88065c6eba 105 SUPERFAMILY SSF82607 3 95 6.93E-21 T 12-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily TSC_c21320 c722f8395732efd7dd760d88065c6eba 105 Pfam PF02575 YbaB/EbfC DNA-binding family 8 96 2.4E-22 T 12-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family TSC_c20340 d16db5cd7c8c85ff5581a67e45691d6c 141 Gene3D G3DSA:2.60.40.790 1 140 3.7E-30 T 12-10-2018 IPR008978 HSP20-like chaperone TSC_c20340 d16db5cd7c8c85ff5581a67e45691d6c 141 Pfam PF00011 Hsp20/alpha crystallin family 40 139 8.4E-18 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain TSC_c20340 d16db5cd7c8c85ff5581a67e45691d6c 141 SUPERFAMILY SSF49764 19 140 1.15E-31 T 12-10-2018 IPR008978 HSP20-like chaperone TSC_c24340 215a0fa44ddae0b043e945f91daa96e8 272 Gene3D G3DSA:2.170.120.30 28 123 1.2E-9 T 12-10-2018 TSC_c22880 22ed701878585c25935383d913ee2567 247 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 2 239 15.507 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TSC_c22880 22ed701878585c25935383d913ee2567 247 Pfam PF00902 Sec-independent protein translocase protein (TatC) 8 222 3.3E-62 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TSC_c22880 22ed701878585c25935383d913ee2567 247 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 6 227 1.2E-60 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TSC_c22880 22ed701878585c25935383d913ee2567 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 103 129 2.0E-36 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TSC_c22880 22ed701878585c25935383d913ee2567 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 5 32 2.0E-36 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TSC_c22880 22ed701878585c25935383d913ee2567 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 154 182 2.0E-36 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TSC_c22880 22ed701878585c25935383d913ee2567 247 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 85 103 2.0E-36 T 12-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 TSC_c19500 120206a087bad1c8294dd7c03ecb8f66 528 Pfam PF11941 Domain of unknown function (DUF3459) 442 524 1.3E-4 T 12-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) TSC_c19500 120206a087bad1c8294dd7c03ecb8f66 528 SUPERFAMILY SSF51011 458 526 2.09E-5 T 12-10-2018 TSC_c19500 120206a087bad1c8294dd7c03ecb8f66 528 SUPERFAMILY SSF51445 2 456 2.23E-145 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TSC_c19500 120206a087bad1c8294dd7c03ecb8f66 528 SMART SM00642 10 388 5.6E-146 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSC_c19500 120206a087bad1c8294dd7c03ecb8f66 528 Gene3D G3DSA:3.20.20.80 2 451 4.5E-178 T 12-10-2018 TSC_c19500 120206a087bad1c8294dd7c03ecb8f66 528 Gene3D G3DSA:3.90.400.10 102 172 4.5E-178 T 12-10-2018 TSC_c19500 120206a087bad1c8294dd7c03ecb8f66 528 Pfam PF00128 Alpha amylase, catalytic domain 25 367 1.7E-100 T 12-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 TSC_c19500 120206a087bad1c8294dd7c03ecb8f66 528 Gene3D G3DSA:2.60.40.1180 462 528 4.2E-5 T 12-10-2018 IPR013780 Glycosyl hydrolase, all-beta TSC_c20210 aa51ffdfebabe40a221bc67a2adaee7e 257 SUPERFAMILY SSF51182 5 249 7.26E-54 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TSC_c20210 aa51ffdfebabe40a221bc67a2adaee7e 257 Gene3D G3DSA:2.60.120.10 9 170 4.2E-46 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TSC_c18900 7184f6d97737b8288e6e54117e96866e 331 Pfam PF04471 Restriction endonuclease 187 298 3.1E-22 T 12-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 TSC_c18900 7184f6d97737b8288e6e54117e96866e 331 PIRSF PIRSF031853 1 326 2.9E-111 T 12-10-2018 IPR016984 Uncharacterised conserved protein UCP031853 TSC_c18900 7184f6d97737b8288e6e54117e96866e 331 SUPERFAMILY SSF52980 189 297 1.07E-11 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSC_c23520 e68f660bf1ff7a039680886e21163ed7 269 Gene3D G3DSA:3.40.50.300 23 159 6.8E-27 T 12-10-2018 TSC_c23520 e68f660bf1ff7a039680886e21163ed7 269 SUPERFAMILY SSF52540 27 166 2.56E-25 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c23520 e68f660bf1ff7a039680886e21163ed7 269 Pfam PF13177 DNA polymerase III, delta subunit 60 159 1.4E-18 T 12-10-2018 TSC_c14620 d9ff29c35ef7a3982d60f696872c1738 1061 SUPERFAMILY SSF53706 44 874 1.08E-93 T 12-10-2018 TSC_c14620 d9ff29c35ef7a3982d60f696872c1738 1061 Gene3D G3DSA:3.40.50.740 578 758 2.8E-14 T 12-10-2018 TSC_c14620 d9ff29c35ef7a3982d60f696872c1738 1061 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 45 113 2.0E-5 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c14620 d9ff29c35ef7a3982d60f696872c1738 1061 Pfam PF01568 Molydopterin dinucleotide binding domain 906 1031 8.0E-10 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSC_c14620 d9ff29c35ef7a3982d60f696872c1738 1061 SUPERFAMILY SSF50692 900 1061 2.94E-20 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSC_c14620 d9ff29c35ef7a3982d60f696872c1738 1061 Pfam PF00384 Molybdopterin oxidoreductase 297 703 1.4E-14 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c14620 d9ff29c35ef7a3982d60f696872c1738 1061 Gene3D G3DSA:3.40.50.740 35 163 5.9E-17 T 12-10-2018 TSC_c14620 d9ff29c35ef7a3982d60f696872c1738 1061 Gene3D G3DSA:2.40.40.20 895 1034 4.6E-20 T 12-10-2018 TSC_c14620 d9ff29c35ef7a3982d60f696872c1738 1061 SMART SM00926 43 114 4.5E-8 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06590 237e8956328b835f68ec6ff353151dc7 307 Gene3D G3DSA:3.30.160.20 156 251 1.3E-90 T 12-10-2018 TSC_c06590 237e8956328b835f68ec6ff353151dc7 307 Pfam PF03462 PCRF domain 4 150 3.8E-44 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 TSC_c06590 237e8956328b835f68ec6ff353151dc7 307 Pfam PF00472 RF-1 domain 159 267 1.7E-37 T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TSC_c06590 237e8956328b835f68ec6ff353151dc7 307 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 8 295 2.7E-118 T 12-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 TSC_c06590 237e8956328b835f68ec6ff353151dc7 307 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 175 191 - T 12-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 TSC_c06590 237e8956328b835f68ec6ff353151dc7 307 SUPERFAMILY SSF75620 3 295 8.63E-112 T 12-10-2018 TSC_c06590 237e8956328b835f68ec6ff353151dc7 307 SMART SM00937 16 125 4.8E-42 T 12-10-2018 IPR005139 Peptide chain release factor GO:0006415 TSC_c06590 237e8956328b835f68ec6ff353151dc7 307 Gene3D G3DSA:3.30.70.1660 60 287 1.3E-90 T 12-10-2018 TSC_c06590 237e8956328b835f68ec6ff353151dc7 307 Gene3D G3DSA:1.20.58.410 1 53 1.4E-12 T 12-10-2018 TSC_c12780 72090a4350ffbba607d2eec6f3a0cb07 222 Gene3D G3DSA:3.40.630.30 11 221 4.8E-45 T 12-10-2018 TSC_c12780 72090a4350ffbba607d2eec6f3a0cb07 222 SUPERFAMILY SSF55729 23 152 1.15E-11 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSC_c12780 72090a4350ffbba607d2eec6f3a0cb07 222 Pfam PF00583 Acetyltransferase (GNAT) family 57 146 1.2E-4 T 12-10-2018 IPR000182 GNAT domain TSC_c05680 09f3332a0efc927b9c538e3194f84556 431 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 2 426 15.009 T 12-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 TSC_c05680 09f3332a0efc927b9c538e3194f84556 431 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 249 424 1.0E-59 T 12-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c05680 09f3332a0efc927b9c538e3194f84556 431 Pfam PF02096 60Kd inner membrane protein 250 424 1.1E-56 T 12-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 TSC_c09710 5c0e69fe2e24f9d75ae30448e132ddb0 163 Pfam PF03259 Roadblock/LC7 domain 19 109 1.3E-20 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain TSC_c09710 5c0e69fe2e24f9d75ae30448e132ddb0 163 Gene3D G3DSA:3.30.450.30 1 138 5.0E-42 T 12-10-2018 TSC_c09710 5c0e69fe2e24f9d75ae30448e132ddb0 163 SUPERFAMILY SSF103196 6 134 2.44E-29 T 12-10-2018 TSC_c09710 5c0e69fe2e24f9d75ae30448e132ddb0 163 SMART SM00960 17 109 1.6E-14 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain TSC_c19400 93eb8164887ea29bd65b443b26d4ea68 560 Gene3D G3DSA:3.90.226.10 9 276 3.7E-85 T 12-10-2018 TSC_c19400 93eb8164887ea29bd65b443b26d4ea68 560 SUPERFAMILY SSF52096 287 553 3.42E-79 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSC_c19400 93eb8164887ea29bd65b443b26d4ea68 560 SUPERFAMILY SSF52096 28 279 4.39E-67 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSC_c19400 93eb8164887ea29bd65b443b26d4ea68 560 Pfam PF01039 Carboxyl transferase domain 55 552 1.2E-137 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TSC_c19400 93eb8164887ea29bd65b443b26d4ea68 560 Gene3D G3DSA:3.90.226.10 284 557 6.6E-91 T 12-10-2018 TSC_c25040 27cdffcb58d587867385e01c153e3267 250 SUPERFAMILY SSF52540 8 247 3.55E-60 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c25040 27cdffcb58d587867385e01c153e3267 250 Gene3D G3DSA:3.40.50.300 4 249 3.9E-87 T 12-10-2018 TSC_c25040 27cdffcb58d587867385e01c153e3267 250 Pfam PF13614 AAA domain 8 171 1.9E-44 T 12-10-2018 IPR025669 AAA domain TSC_c25040 27cdffcb58d587867385e01c153e3267 250 PIRSF PIRSF009320 85 249 1.1E-10 T 12-10-2018 TSC_c25040 27cdffcb58d587867385e01c153e3267 250 PIRSF PIRSF009320 7 80 3.1E-17 T 12-10-2018 TSC_c15790 73b1aa4933e637e99b166af0c1bb4d04 130 Pfam PF02661 Fic/DOC family 1 82 3.3E-15 T 12-10-2018 IPR003812 Fido domain TSC_c15790 73b1aa4933e637e99b166af0c1bb4d04 130 SUPERFAMILY SSF140931 1 89 1.57E-9 T 12-10-2018 IPR036597 Fido-like domain superfamily TSC_c15790 73b1aa4933e637e99b166af0c1bb4d04 130 Gene3D G3DSA:1.20.120.1870 1 126 1.6E-32 T 12-10-2018 TSC_c15790 73b1aa4933e637e99b166af0c1bb4d04 130 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 3 101 9.3E-14 T 12-10-2018 IPR006440 Death on curing protein GO:0016301 TSC_c22660 e9b3be60bc429c402658bf98ba8ea29c 516 Pfam PF00171 Aldehyde dehydrogenase family 46 512 2.5E-153 T 12-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 TSC_c22660 e9b3be60bc429c402658bf98ba8ea29c 516 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 287 294 - T 12-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 TSC_c22660 e9b3be60bc429c402658bf98ba8ea29c 516 Gene3D G3DSA:3.40.605.10 40 503 7.2E-184 T 12-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 TSC_c22660 e9b3be60bc429c402658bf98ba8ea29c 516 SUPERFAMILY SSF53720 4 515 3.67E-156 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSC_c22660 e9b3be60bc429c402658bf98ba8ea29c 516 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 315 326 - T 12-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 TSC_c22660 e9b3be60bc429c402658bf98ba8ea29c 516 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 6 516 2.3E-221 T 12-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 TSC_c22660 e9b3be60bc429c402658bf98ba8ea29c 516 Gene3D G3DSA:3.40.309.10 290 479 7.2E-184 T 12-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 TSC_c04420 e345c215e34b913c3f3252fd3107a4f7 309 SMART SM00382 38 231 4.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c04420 e345c215e34b913c3f3252fd3107a4f7 309 Gene3D G3DSA:3.40.50.300 9 262 7.9E-51 T 12-10-2018 TSC_c04420 e345c215e34b913c3f3252fd3107a4f7 309 SUPERFAMILY SSF52540 11 235 3.33E-51 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c04420 e345c215e34b913c3f3252fd3107a4f7 309 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c04420 e345c215e34b913c3f3252fd3107a4f7 309 Pfam PF00005 ABC transporter 29 173 1.1E-24 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c14010 7c28ef4b2ce17312569c62ed8ed09112 616 SUPERFAMILY SSF52317 436 615 1.46E-45 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c14010 7c28ef4b2ce17312569c62ed8ed09112 616 Pfam PF00425 chorismate binding enzyme 148 398 3.2E-86 T 12-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal TSC_c14010 7c28ef4b2ce17312569c62ed8ed09112 616 PRINTS PR00096 Glutamine amidotransferase superfamily signature 478 487 4.4E-11 T 12-10-2018 TSC_c14010 7c28ef4b2ce17312569c62ed8ed09112 616 PRINTS PR00096 Glutamine amidotransferase superfamily signature 592 605 4.4E-11 T 12-10-2018 TSC_c14010 7c28ef4b2ce17312569c62ed8ed09112 616 PRINTS PR00096 Glutamine amidotransferase superfamily signature 506 517 4.4E-11 T 12-10-2018 TSC_c14010 7c28ef4b2ce17312569c62ed8ed09112 616 PRINTS PR00097 Anthranilate synthase component II signature 592 605 8.1E-26 T 12-10-2018 TSC_c14010 7c28ef4b2ce17312569c62ed8ed09112 616 PRINTS PR00097 Anthranilate synthase component II signature 506 517 8.1E-26 T 12-10-2018 TSC_c14010 7c28ef4b2ce17312569c62ed8ed09112 616 PRINTS PR00097 Anthranilate synthase component II signature 530 538 8.1E-26 T 12-10-2018 TSC_c14010 7c28ef4b2ce17312569c62ed8ed09112 616 PRINTS PR00097 Anthranilate synthase component II signature 437 451 8.1E-26 T 12-10-2018 TSC_c14010 7c28ef4b2ce17312569c62ed8ed09112 616 PRINTS PR00097 Anthranilate synthase component II signature 478 487 8.1E-26 T 12-10-2018 TSC_c14010 7c28ef4b2ce17312569c62ed8ed09112 616 PRINTS PR00097 Anthranilate synthase component II signature 550 562 8.1E-26 T 12-10-2018 TSC_c14010 7c28ef4b2ce17312569c62ed8ed09112 616 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 437 614 1.7E-37 T 12-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 TSC_c14010 7c28ef4b2ce17312569c62ed8ed09112 616 SUPERFAMILY SSF56322 15 407 2.49E-111 T 12-10-2018 IPR005801 ADC synthase GO:0009058 TSC_c14010 7c28ef4b2ce17312569c62ed8ed09112 616 Gene3D G3DSA:3.60.120.10 5 408 3.5E-113 T 12-10-2018 IPR005801 ADC synthase GO:0009058 TSC_c14010 7c28ef4b2ce17312569c62ed8ed09112 616 Pfam PF00117 Glutamine amidotransferase class-I 440 614 6.5E-39 T 12-10-2018 IPR017926 Glutamine amidotransferase TSC_c14010 7c28ef4b2ce17312569c62ed8ed09112 616 Gene3D G3DSA:3.40.50.880 435 616 1.3E-55 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c12950 ce4ff572078b128b0c8341cf0ff10e51 347 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 107 118 - T 12-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 TSC_c12950 ce4ff572078b128b0c8341cf0ff10e51 347 PIRSF PIRSF000530 1 344 1.7E-105 T 12-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TSC_c12950 ce4ff572078b128b0c8341cf0ff10e51 347 SUPERFAMILY SSF54211 3 189 9.11E-52 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c12950 ce4ff572078b128b0c8341cf0ff10e51 347 Gene3D G3DSA:3.30.230.10 15 187 4.2E-108 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSC_c12950 ce4ff572078b128b0c8341cf0ff10e51 347 PRINTS PR00473 Galactokinase signature 19 37 2.3E-21 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TSC_c12950 ce4ff572078b128b0c8341cf0ff10e51 347 PRINTS PR00473 Galactokinase signature 98 116 2.3E-21 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TSC_c12950 ce4ff572078b128b0c8341cf0ff10e51 347 PRINTS PR00473 Galactokinase signature 246 260 2.3E-21 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TSC_c12950 ce4ff572078b128b0c8341cf0ff10e51 347 Gene3D G3DSA:3.30.70.890 188 337 4.2E-108 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TSC_c12950 ce4ff572078b128b0c8341cf0ff10e51 347 SUPERFAMILY SSF55060 193 342 8.32E-43 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TSC_c12950 ce4ff572078b128b0c8341cf0ff10e51 347 PRINTS PR00959 Mevalonate kinase family signature 148 167 6.4E-40 T 12-10-2018 TSC_c12950 ce4ff572078b128b0c8341cf0ff10e51 347 PRINTS PR00959 Mevalonate kinase family signature 105 127 6.4E-40 T 12-10-2018 TSC_c12950 ce4ff572078b128b0c8341cf0ff10e51 347 PRINTS PR00959 Mevalonate kinase family signature 309 326 6.4E-40 T 12-10-2018 TSC_c12950 ce4ff572078b128b0c8341cf0ff10e51 347 PRINTS PR00959 Mevalonate kinase family signature 17 41 6.4E-40 T 12-10-2018 TSC_c12950 ce4ff572078b128b0c8341cf0ff10e51 347 Pfam PF00288 GHMP kinases N terminal domain 101 167 3.5E-16 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TSC_c12950 ce4ff572078b128b0c8341cf0ff10e51 347 Pfam PF10509 Galactokinase galactose-binding signature 3 46 2.7E-15 T 12-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TSC_c12950 ce4ff572078b128b0c8341cf0ff10e51 347 Pfam PF08544 GHMP kinases C terminal 263 334 1.7E-16 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain TSC_c12950 ce4ff572078b128b0c8341cf0ff10e51 347 TIGRFAM TIGR00131 gal_kin: galactokinase 3 343 3.0E-80 T 12-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 TSC_c13960 f58bb28d6d37d720f2da195e4df45d61 252 SMART SM00854 2 188 0.0062 T 12-10-2018 IPR019079 Capsule synthesis protein, CapA TSC_c13960 f58bb28d6d37d720f2da195e4df45d61 252 Gene3D G3DSA:3.60.21.10 1 252 2.0E-102 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TSC_c13960 f58bb28d6d37d720f2da195e4df45d61 252 PIRSF PIRSF004789 1 250 2.8E-77 T 12-10-2018 IPR005235 Metallophosphoesterase, YmdB-like TSC_c13960 f58bb28d6d37d720f2da195e4df45d61 252 SUPERFAMILY SSF56300 1 234 4.88E-76 T 12-10-2018 TSC_c13960 f58bb28d6d37d720f2da195e4df45d61 252 Pfam PF13277 YmdB-like protein 4 238 1.6E-86 T 12-10-2018 IPR005235 Metallophosphoesterase, YmdB-like TSC_c18440 290071d785e8f05dc239f5f17af043d1 188 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 3 188 18.878 T 12-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 TSC_c18440 290071d785e8f05dc239f5f17af043d1 188 Gene3D G3DSA:3.90.550.10 4 188 1.0E-40 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c18440 290071d785e8f05dc239f5f17af043d1 188 Pfam PF12804 MobA-like NTP transferase domain 7 158 1.8E-31 T 12-10-2018 IPR025877 MobA-like NTP transferase TSC_c18440 290071d785e8f05dc239f5f17af043d1 188 SUPERFAMILY SSF53448 6 187 8.11E-32 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c09330 54ee87972f6c7764f4fbe176f8c1bf87 331 Pfam PF02562 PhoH-like protein 118 321 2.3E-98 T 12-10-2018 IPR003714 PhoH-like protein GO:0005524 TSC_c09330 54ee87972f6c7764f4fbe176f8c1bf87 331 Gene3D G3DSA:3.40.50.300 116 321 9.6E-78 T 12-10-2018 TSC_c09330 54ee87972f6c7764f4fbe176f8c1bf87 331 SUPERFAMILY SSF52540 117 296 2.06E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c14340 3feead8215a7224b4f239ee6f35951fe 247 Gene3D G3DSA:3.30.420.10 68 232 1.6E-43 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSC_c14340 3feead8215a7224b4f239ee6f35951fe 247 Pfam PF00929 Exonuclease 74 226 4.0E-30 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TSC_c14340 3feead8215a7224b4f239ee6f35951fe 247 SMART SM00479 72 236 1.7E-35 T 12-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III TSC_c14340 3feead8215a7224b4f239ee6f35951fe 247 SUPERFAMILY SSF53098 73 234 1.86E-44 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c12790 60383211cdd8c4eff8fd60a0dbc6c899 447 SUPERFAMILY SSF53383 30 441 1.02E-119 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c12790 60383211cdd8c4eff8fd60a0dbc6c899 447 Gene3D G3DSA:3.40.640.10 70 337 1.2E-148 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c12790 60383211cdd8c4eff8fd60a0dbc6c899 447 Gene3D G3DSA:3.90.1150.10 12 434 1.2E-148 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c12790 60383211cdd8c4eff8fd60a0dbc6c899 447 Pfam PF00202 Aminotransferase class-III 35 435 2.1E-109 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c12790 60383211cdd8c4eff8fd60a0dbc6c899 447 PIRSF PIRSF000521 3 140 6.8E-8 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c12790 60383211cdd8c4eff8fd60a0dbc6c899 447 PIRSF PIRSF000521 134 442 1.8E-31 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c11650 6ad95fc4d93a487c9dbcc157d9f1def8 186 Pfam PF02566 OsmC-like protein 78 182 1.5E-20 T 12-10-2018 IPR003718 OsmC/Ohr family TSC_c11650 6ad95fc4d93a487c9dbcc157d9f1def8 186 SUPERFAMILY SSF82784 7 185 1.44E-41 T 12-10-2018 IPR036102 OsmC/Ohr superfamily TSC_c11650 6ad95fc4d93a487c9dbcc157d9f1def8 186 Gene3D G3DSA:3.30.300.20 2 174 2.5E-50 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TSC_c21540 3e1bbc598e964544fdd9eba3d2a3f355 204 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 2 200 34.505 T 12-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 TSC_c21540 3e1bbc598e964544fdd9eba3d2a3f355 204 Gene3D G3DSA:3.20.20.70 2 200 2.4E-78 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c21540 3e1bbc598e964544fdd9eba3d2a3f355 204 SUPERFAMILY SSF51366 3 195 4.55E-59 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSC_c21540 3e1bbc598e964544fdd9eba3d2a3f355 204 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 4 194 1.7E-41 T 12-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 TSC_c23690 63c86346eb0c3ee0d450762bdff55c0b 371 SUPERFAMILY SSF55031 178 270 1.06E-16 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSC_c23690 63c86346eb0c3ee0d450762bdff55c0b 371 Pfam PF01546 Peptidase family M20/M25/M40 78 369 2.7E-26 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 TSC_c23690 63c86346eb0c3ee0d450762bdff55c0b 371 Pfam PF07687 Peptidase dimerisation domain 175 267 1.2E-15 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain TSC_c23690 63c86346eb0c3ee0d450762bdff55c0b 371 Gene3D G3DSA:3.40.630.10 17 360 1.3E-109 T 12-10-2018 TSC_c23690 63c86346eb0c3ee0d450762bdff55c0b 371 SUPERFAMILY SSF53187 3 371 1.01E-46 T 12-10-2018 TSC_c23690 63c86346eb0c3ee0d450762bdff55c0b 371 Gene3D G3DSA:3.30.70.360 178 285 1.3E-109 T 12-10-2018 TSC_c23690 63c86346eb0c3ee0d450762bdff55c0b 371 PIRSF PIRSF037238 1 371 5.1E-136 T 12-10-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase TSC_c18220 4d9f2fd0bc28c2b20315801a5ede8b97 299 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 36 288 1.3E-38 T 12-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 TSC_c18220 4d9f2fd0bc28c2b20315801a5ede8b97 299 Gene3D G3DSA:1.20.272.10 172 293 8.7E-25 T 12-10-2018 TSC_c18220 4d9f2fd0bc28c2b20315801a5ede8b97 299 Gene3D G3DSA:1.10.8.60 107 168 8.2E-8 T 12-10-2018 TSC_c18220 4d9f2fd0bc28c2b20315801a5ede8b97 299 SUPERFAMILY SSF52540 49 165 4.35E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c18220 4d9f2fd0bc28c2b20315801a5ede8b97 299 SUPERFAMILY SSF48019 172 290 4.08E-21 T 12-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 TSC_c24490 5fb62d5c665a03c6d5e7fbfdd3da61ed 98 SUPERFAMILY SSF143800 1 95 1.29E-17 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c24490 5fb62d5c665a03c6d5e7fbfdd3da61ed 98 Gene3D G3DSA:2.20.150.30 1 45 1.0E-25 T 12-10-2018 TSC_c24490 5fb62d5c665a03c6d5e7fbfdd3da61ed 98 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 65 5.5E-14 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c24490 5fb62d5c665a03c6d5e7fbfdd3da61ed 98 Gene3D G3DSA:1.10.20.50 46 89 8.6E-26 T 12-10-2018 TSC_c24490 5fb62d5c665a03c6d5e7fbfdd3da61ed 98 Pfam PF00830 Ribosomal L28 family 3 65 2.0E-11 T 12-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c24490 5fb62d5c665a03c6d5e7fbfdd3da61ed 98 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 85 16.169 T 12-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c19410 b7ccd91e6280c029e1f0f86325d15a5a 287 Pfam PF00682 HMGL-like 12 276 2.8E-21 T 12-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 TSC_c19410 b7ccd91e6280c029e1f0f86325d15a5a 287 Gene3D G3DSA:3.20.20.70 3 284 4.1E-85 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c19410 b7ccd91e6280c029e1f0f86325d15a5a 287 SUPERFAMILY SSF51569 8 281 5.13E-42 T 12-10-2018 TSC_c05730 f1dcd8c8e53cfceb7bc83783cac073bc 644 Gene3D G3DSA:3.40.50.12780 329 471 6.9E-36 T 12-10-2018 TSC_c05730 f1dcd8c8e53cfceb7bc83783cac073bc 644 Gene3D G3DSA:3.40.50.12780 8 305 8.1E-49 T 12-10-2018 TSC_c05730 f1dcd8c8e53cfceb7bc83783cac073bc 644 SUPERFAMILY SSF56801 8 609 4.06E-116 T 12-10-2018 TSC_c05730 f1dcd8c8e53cfceb7bc83783cac073bc 644 Pfam PF00501 AMP-binding enzyme 22 478 1.3E-88 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSC_c23490 6aca06b406e3400fb925151041df655d 307 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 288 2.6E-44 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSC_c09210 19e6f734bf2a78c3cfdc30c670631e8c 400 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 4 397 53.969 T 12-10-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TSC_c09210 19e6f734bf2a78c3cfdc30c670631e8c 400 PIRSF PIRSF001259 3 400 1.9E-176 T 12-10-2018 TSC_c09210 19e6f734bf2a78c3cfdc30c670631e8c 400 Gene3D G3DSA:3.90.870.10 1 205 1.8E-88 T 12-10-2018 TSC_c09210 19e6f734bf2a78c3cfdc30c670631e8c 400 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 210 398 4.0E-82 T 12-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TSC_c09210 19e6f734bf2a78c3cfdc30c670631e8c 400 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 206 400 42.952 T 12-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TSC_c09210 19e6f734bf2a78c3cfdc30c670631e8c 400 SUPERFAMILY SSF55821 6 203 8.47E-84 T 12-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily TSC_c09210 19e6f734bf2a78c3cfdc30c670631e8c 400 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 10 199 4.0E-85 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSC_c09210 19e6f734bf2a78c3cfdc30c670631e8c 400 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 3 204 38.815 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSC_c09210 19e6f734bf2a78c3cfdc30c670631e8c 400 Gene3D G3DSA:3.40.50.10990 206 379 2.9E-77 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TSC_c09210 19e6f734bf2a78c3cfdc30c670631e8c 400 Pfam PF00925 GTP cyclohydrolase II 210 375 9.0E-76 T 12-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TSC_c09210 19e6f734bf2a78c3cfdc30c670631e8c 400 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 7 200 2.6E-71 T 12-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 TSC_c09210 19e6f734bf2a78c3cfdc30c670631e8c 400 SUPERFAMILY SSF142695 207 376 3.27E-75 T 12-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 TSC_c15110 05ba3d49ee0eaef46583b8dce83e2ca0 189 Gene3D G3DSA:3.40.1790.10 1 186 9.0E-71 T 12-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TSC_c15110 05ba3d49ee0eaef46583b8dce83e2ca0 189 Pfam PF04227 Indigoidine synthase A like protein 3 178 5.9E-68 T 12-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TSC_c15110 05ba3d49ee0eaef46583b8dce83e2ca0 189 SUPERFAMILY SSF110581 4 182 4.18E-67 T 12-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TSC_c23190 8e02f76f551f13416bb4839dedb169e0 350 Pfam PF00005 ABC transporter 22 159 7.5E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c23190 8e02f76f551f13416bb4839dedb169e0 350 SUPERFAMILY SSF50331 235 331 1.76E-9 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSC_c23190 8e02f76f551f13416bb4839dedb169e0 350 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c23190 8e02f76f551f13416bb4839dedb169e0 350 Gene3D G3DSA:2.40.50.140 273 331 2.4E-7 T 12-10-2018 TSC_c23190 8e02f76f551f13416bb4839dedb169e0 350 SMART SM00382 31 217 3.9E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c23190 8e02f76f551f13416bb4839dedb169e0 350 Gene3D G3DSA:3.40.50.300 6 219 3.3E-65 T 12-10-2018 TSC_c23190 8e02f76f551f13416bb4839dedb169e0 350 Pfam PF08402 TOBE domain 266 330 1.1E-9 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSC_c23190 8e02f76f551f13416bb4839dedb169e0 350 SUPERFAMILY SSF52540 7 238 2.79E-80 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c23190 8e02f76f551f13416bb4839dedb169e0 350 Gene3D G3DSA:2.40.50.940 220 272 2.4E-7 T 12-10-2018 TSC_c04210 aedafbf992616cf37e281f0d29e1e671 212 Gene3D G3DSA:3.30.1370.160 4 60 1.4E-5 T 12-10-2018 TSC_c04210 aedafbf992616cf37e281f0d29e1e671 212 SUPERFAMILY SSF55174 37 206 1.47E-6 T 12-10-2018 TSC_c06960 7f09fb90d3961835b0ace5b959654186 173 SUPERFAMILY SSF89155 8 166 6.15E-33 T 12-10-2018 IPR036411 TorD-like superfamily TSC_c06960 7f09fb90d3961835b0ace5b959654186 173 Gene3D G3DSA:1.10.3480.10 1 171 2.3E-32 T 12-10-2018 TSC_c06960 7f09fb90d3961835b0ace5b959654186 173 Pfam PF02613 Nitrate reductase delta subunit 29 142 2.9E-18 T 12-10-2018 IPR020945 DMSO/Nitrate reductase chaperone TSC_c19270 ca73a37f87a3f1ffd0b68b37ba459e13 291 SUPERFAMILY SSF88713 37 274 1.89E-29 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSC_c19270 ca73a37f87a3f1ffd0b68b37ba459e13 291 Gene3D G3DSA:3.20.20.370 25 288 1.4E-95 T 12-10-2018 TSC_c19270 ca73a37f87a3f1ffd0b68b37ba459e13 291 Pfam PF04794 YdjC-like protein 39 273 3.6E-26 T 12-10-2018 IPR006879 Carbohydrate deacetylase YdjC-like TSC_c15000 c306c04fb7f551b420e079e5f6f80ac0 247 SMART SM00382 32 218 4.6E-18 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c15000 c306c04fb7f551b420e079e5f6f80ac0 247 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c15000 c306c04fb7f551b420e079e5f6f80ac0 247 Gene3D G3DSA:3.40.50.300 4 247 1.4E-87 T 12-10-2018 TSC_c15000 c306c04fb7f551b420e079e5f6f80ac0 247 SUPERFAMILY SSF52540 7 240 1.73E-84 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c15000 c306c04fb7f551b420e079e5f6f80ac0 247 Pfam PF00005 ABC transporter 23 170 6.5E-40 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c15000 c306c04fb7f551b420e079e5f6f80ac0 247 PIRSF PIRSF039085 4 246 1.1E-118 T 12-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 TSC_c20420 be07de78489285c3d4b72a5a6d02f7f1 210 SUPERFAMILY SSF144091 11 209 1.83E-45 T 12-10-2018 TSC_c20420 be07de78489285c3d4b72a5a6d02f7f1 210 Pfam PF01694 Rhomboid family 56 207 1.1E-40 T 12-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 TSC_c20420 be07de78489285c3d4b72a5a6d02f7f1 210 Gene3D G3DSA:1.20.1540.10 8 206 2.6E-34 T 12-10-2018 IPR035952 Rhomboid-like superfamily TSC_c15030 be13201a059430491786324d5c66050c 258 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 64 254 1.1E-22 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c15030 be13201a059430491786324d5c66050c 258 Gene3D G3DSA:1.10.3720.10 37 255 8.1E-53 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c15030 be13201a059430491786324d5c66050c 258 SUPERFAMILY SSF161098 48 239 1.26E-45 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c15030 be13201a059430491786324d5c66050c 258 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 45 148 1.7E-22 T 12-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 TSC_c01060 356a4f69130cc8907955dfa27c239473 390 PRINTS PR01035 Tetracycline resistance protein signature 275 296 1.1E-13 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TSC_c01060 356a4f69130cc8907955dfa27c239473 390 PRINTS PR01035 Tetracycline resistance protein signature 13 29 1.1E-13 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TSC_c01060 356a4f69130cc8907955dfa27c239473 390 PRINTS PR01035 Tetracycline resistance protein signature 336 359 1.1E-13 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TSC_c01060 356a4f69130cc8907955dfa27c239473 390 PRINTS PR01035 Tetracycline resistance protein signature 139 161 1.1E-13 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TSC_c01060 356a4f69130cc8907955dfa27c239473 390 Pfam PF07690 Major Facilitator Superfamily 7 295 7.1E-39 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c01060 356a4f69130cc8907955dfa27c239473 390 Gene3D G3DSA:1.20.1250.20 3 383 1.8E-58 T 12-10-2018 TSC_c01060 356a4f69130cc8907955dfa27c239473 390 SUPERFAMILY SSF103473 4 388 3.92E-53 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c23830 1e83a129acde49ff995173d5fb64d821 270 Pfam PF01875 Memo-like protein 7 259 5.8E-48 T 12-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 TSC_c23830 1e83a129acde49ff995173d5fb64d821 270 Gene3D G3DSA:3.40.830.10 3 262 5.0E-53 T 12-10-2018 TSC_c23830 1e83a129acde49ff995173d5fb64d821 270 Hamap MF_00055 MEMO1 family protein . 3 262 45.363 T 12-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 TSC_c23830 1e83a129acde49ff995173d5fb64d821 270 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 5 260 1.0E-72 T 12-10-2018 TSC_c03970 b639d4af18df55bfe2490d74d6f10a7b 380 Pfam PF02687 FtsX-like permease family 281 371 2.4E-13 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TSC_c03970 b639d4af18df55bfe2490d74d6f10a7b 380 Pfam PF12704 MacB-like periplasmic core domain 18 225 4.3E-22 T 12-10-2018 IPR025857 MacB-like periplasmic core domain TSC_c20480 387501ab2a966c4097f6af43643be3fa 185 Gene3D G3DSA:1.10.490.10 7 158 2.7E-33 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TSC_c20480 387501ab2a966c4097f6af43643be3fa 185 Pfam PF11563 Protoglobin 7 156 1.3E-26 T 12-10-2018 TSC_c20480 387501ab2a966c4097f6af43643be3fa 185 SUPERFAMILY SSF46458 7 149 8.2E-28 T 12-10-2018 IPR009050 Globin-like superfamily TSC_c09880 7e5a74e5a50e62a74eee9ac4bef3d929 312 Gene3D G3DSA:3.40.50.1820 89 311 5.6E-37 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c09880 7e5a74e5a50e62a74eee9ac4bef3d929 312 SUPERFAMILY SSF53474 106 309 8.87E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c09880 7e5a74e5a50e62a74eee9ac4bef3d929 312 Pfam PF00756 Putative esterase 120 307 4.3E-21 T 12-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 TSC_c23000 adbb2281539d93a6037ea43be34e270b 100 Pfam PF01909 Nucleotidyltransferase domain 16 57 1.2E-9 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSC_c23000 adbb2281539d93a6037ea43be34e270b 100 Gene3D G3DSA:3.30.460.10 2 96 5.5E-14 T 12-10-2018 TSC_c23000 adbb2281539d93a6037ea43be34e270b 100 SUPERFAMILY SSF81301 13 88 4.3E-14 T 12-10-2018 TSC_c23320 0a3db44146dcc579fc19fa82606b4042 257 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 172 182 - T 12-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSC_c23320 0a3db44146dcc579fc19fa82606b4042 257 SUPERFAMILY SSF53681 109 242 1.96E-33 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSC_c23320 0a3db44146dcc579fc19fa82606b4042 257 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 206 2.8E-32 T 12-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSC_c23320 0a3db44146dcc579fc19fa82606b4042 257 TIGRFAM TIGR00067 glut_race: glutamate racemase 8 240 4.0E-62 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSC_c23320 0a3db44146dcc579fc19fa82606b4042 257 SUPERFAMILY SSF53681 7 107 1.08E-35 T 12-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSC_c23320 0a3db44146dcc579fc19fa82606b4042 257 Gene3D G3DSA:3.40.50.1860 97 198 1.7E-77 T 12-10-2018 TSC_c23320 0a3db44146dcc579fc19fa82606b4042 257 Gene3D G3DSA:3.40.50.1860 7 242 1.7E-77 T 12-10-2018 TSC_c23320 0a3db44146dcc579fc19fa82606b4042 257 Hamap MF_00258 Glutamate racemase [murI]. 6 246 33.333 T 12-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSC_c23320 0a3db44146dcc579fc19fa82606b4042 257 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 72 80 - T 12-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 TSC_c08690 2b6abb9799ef0f6249ae5d87a61c5e9a 123 Pfam PF12723 Protein of unknown function (DUF3809) 20 115 1.5E-14 T 12-10-2018 IPR024219 Protein of unknown function DUF3809 TSC_c08690 2b6abb9799ef0f6249ae5d87a61c5e9a 123 Gene3D G3DSA:3.30.530.70 17 122 9.9E-15 T 12-10-2018 TSC_c19700 331a1fbfa8f236c4de1801936472b454 452 Gene3D G3DSA:1.10.3720.10 240 447 1.1E-13 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c19700 331a1fbfa8f236c4de1801936472b454 452 SUPERFAMILY SSF161098 249 434 3.92E-18 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c19700 331a1fbfa8f236c4de1801936472b454 452 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 12 57 1.8E-11 T 12-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain TSC_c19700 331a1fbfa8f236c4de1801936472b454 452 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 274 451 1.7E-25 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c04940 55a72cc5d72d00f04b9fa7239b29b97f 409 Gene3D G3DSA:3.40.1350.30 113 245 3.5E-55 T 12-10-2018 TSC_c04940 55a72cc5d72d00f04b9fa7239b29b97f 409 SUPERFAMILY SSF50249 3 45 1.03E-5 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c04940 55a72cc5d72d00f04b9fa7239b29b97f 409 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 242 403 6.4E-15 T 12-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 TSC_c04940 55a72cc5d72d00f04b9fa7239b29b97f 409 Gene3D G3DSA:3.40.50.150 73 400 3.5E-55 T 12-10-2018 TSC_c04940 55a72cc5d72d00f04b9fa7239b29b97f 409 SUPERFAMILY SSF53335 73 403 9.35E-47 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c04940 55a72cc5d72d00f04b9fa7239b29b97f 409 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 337 368 - T 12-10-2018 IPR030390 RNA methyltransferase TrmA, active site TSC_c04940 55a72cc5d72d00f04b9fa7239b29b97f 409 Gene3D G3DSA:2.40.50.140 1 67 3.2E-7 T 12-10-2018 TSC_c07900 36afb305c793b38e8b8165c392499676 122 SUPERFAMILY SSF46785 3 120 6.96E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c07900 36afb305c793b38e8b8165c392499676 122 Pfam PF01475 Ferric uptake regulator family 3 91 2.8E-20 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TSC_c07900 36afb305c793b38e8b8165c392499676 122 Gene3D G3DSA:1.10.10.10 2 71 3.1E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c07900 36afb305c793b38e8b8165c392499676 122 Gene3D G3DSA:3.30.1490.190 73 122 1.6E-8 T 12-10-2018 TSC_c23670 cc38d8560631323e0d0cc2216e21f3a6 420 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 278 373 1.5E-8 T 12-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 TSC_c23670 cc38d8560631323e0d0cc2216e21f3a6 420 Gene3D G3DSA:1.20.810.10 1 407 9.5E-96 T 12-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 TSC_c23670 cc38d8560631323e0d0cc2216e21f3a6 420 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 97 272 8.7E-46 T 12-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 TSC_c23670 cc38d8560631323e0d0cc2216e21f3a6 420 SUPERFAMILY SSF81342 3 267 1.88E-54 T 12-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 TSC_c23670 cc38d8560631323e0d0cc2216e21f3a6 420 SUPERFAMILY SSF81648 229 372 4.47E-20 T 12-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 TSC_c17450 64138096e04c3b9fddbfca83075495bf 84 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 14 83 1.1E-34 T 12-10-2018 IPR018720 Domain of unknown function DUF2249 TSC_c03210 b0cd2d71f0267a43a850b838905bf786 121 Pfam PF04519 Polymer-forming cytoskeletal 11 106 8.2E-24 T 12-10-2018 IPR007607 Bactofilin A/B TSC_c22320 e429bc869c5fa2d46350546378dbc72d 182 Pfam PF00673 ribosomal L5P family C-terminus 87 180 6.2E-39 T 12-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22320 e429bc869c5fa2d46350546378dbc72d 182 SUPERFAMILY SSF55282 7 182 3.3E-74 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22320 e429bc869c5fa2d46350546378dbc72d 182 ProSitePatterns PS00358 Ribosomal protein L5 signature. 60 76 - T 12-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22320 e429bc869c5fa2d46350546378dbc72d 182 PIRSF PIRSF002161 3 182 9.4E-65 T 12-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22320 e429bc869c5fa2d46350546378dbc72d 182 Pfam PF00281 Ribosomal protein L5 27 83 1.3E-25 T 12-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c22320 e429bc869c5fa2d46350546378dbc72d 182 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 4 182 43.652 T 12-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22320 e429bc869c5fa2d46350546378dbc72d 182 Gene3D G3DSA:3.30.1440.10 1 182 2.6E-83 T 12-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 TSC_c13470 597d090a42a3a317ff107f105e6179e4 492 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 74 491 3.6E-179 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 TSC_c13470 597d090a42a3a317ff107f105e6179e4 492 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 73 492 100.136 T 12-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 TSC_c13470 597d090a42a3a317ff107f105e6179e4 492 SUPERFAMILY SSF53383 70 492 4.81E-132 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c13470 597d090a42a3a317ff107f105e6179e4 492 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 303 339 - T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c13470 597d090a42a3a317ff107f105e6179e4 492 Pfam PF00202 Aminotransferase class-III 104 464 6.1E-75 T 12-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 TSC_c13470 597d090a42a3a317ff107f105e6179e4 492 Gene3D G3DSA:3.90.1150.10 78 487 2.6E-178 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c13470 597d090a42a3a317ff107f105e6179e4 492 Gene3D G3DSA:3.40.640.10 139 387 2.6E-178 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c19920 948a7a4ecbdc4e91b2b3559c2f0fc177 117 Gene3D G3DSA:3.40.50.12740 1 117 1.9E-29 T 12-10-2018 TSC_c19920 948a7a4ecbdc4e91b2b3559c2f0fc177 117 SMART SM00448 1 110 9.5E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c19920 948a7a4ecbdc4e91b2b3559c2f0fc177 117 SUPERFAMILY SSF52172 1 115 1.57E-32 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c19920 948a7a4ecbdc4e91b2b3559c2f0fc177 117 Pfam PF00072 Response regulator receiver domain 1 110 4.0E-23 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c07040 0ce12515a969f3e44ddfaaec19ee4eaf 393 SUPERFAMILY SSF53335 196 369 7.92E-25 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c07040 0ce12515a969f3e44ddfaaec19ee4eaf 393 Gene3D G3DSA:3.40.50.150 178 392 7.9E-50 T 12-10-2018 TSC_c07040 0ce12515a969f3e44ddfaaec19ee4eaf 393 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 319 325 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TSC_c07040 0ce12515a969f3e44ddfaaec19ee4eaf 393 SUPERFAMILY SSF53335 24 141 4.9E-6 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c07040 0ce12515a969f3e44ddfaaec19ee4eaf 393 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 235 262 - T 12-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 TSC_c07040 0ce12515a969f3e44ddfaaec19ee4eaf 393 Gene3D G3DSA:3.40.50.150 1 177 2.8E-40 T 12-10-2018 TSC_c07040 0ce12515a969f3e44ddfaaec19ee4eaf 393 Pfam PF05175 Methyltransferase small domain 196 293 8.9E-18 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TSC_c07040 0ce12515a969f3e44ddfaaec19ee4eaf 393 Pfam PF05175 Methyltransferase small domain 312 385 5.0E-19 T 12-10-2018 IPR007848 Methyltransferase small domain GO:0008168 TSC_c17740 8f9ec2f0276a70dec5a5ae842e346f75 111 SUPERFAMILY SSF64307 17 103 1.44E-16 T 12-10-2018 IPR036868 TusA-like domain superfamily TSC_c17740 8f9ec2f0276a70dec5a5ae842e346f75 111 Gene3D G3DSA:3.30.110.40 35 110 1.9E-10 T 12-10-2018 IPR036868 TusA-like domain superfamily TSC_c17740 8f9ec2f0276a70dec5a5ae842e346f75 111 Pfam PF01206 Sulfurtransferase TusA 37 110 3.4E-11 T 12-10-2018 IPR001455 TusA-like domain TSC_c10710 a9ebdd19ad49059bbfcf1c103863c885 494 Gene3D G3DSA:3.40.190.10 15 265 3.1E-70 T 12-10-2018 TSC_c10710 a9ebdd19ad49059bbfcf1c103863c885 494 SUPERFAMILY SSF53850 20 488 3.08E-135 T 12-10-2018 TSC_c10710 a9ebdd19ad49059bbfcf1c103863c885 494 Gene3D G3DSA:3.10.105.10 266 460 2.3E-46 T 12-10-2018 TSC_c10710 a9ebdd19ad49059bbfcf1c103863c885 494 PIRSF PIRSF002741 16 494 3.4E-104 T 12-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 TSC_c10710 a9ebdd19ad49059bbfcf1c103863c885 494 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 66 402 7.0E-95 T 12-10-2018 IPR000914 Solute-binding protein family 5 domain TSC_c01890 197fa89c59815b5f683dee1603c4b59a 163 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 3 156 5.0E-51 T 12-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 TSC_c01890 197fa89c59815b5f683dee1603c4b59a 163 Gene3D G3DSA:3.20.19.10 2 159 5.9E-47 T 12-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 TSC_c01890 197fa89c59815b5f683dee1603c4b59a 163 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 1 159 32.198 T 12-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 TSC_c01890 197fa89c59815b5f683dee1603c4b59a 163 SUPERFAMILY SSF52016 3 158 1.51E-41 T 12-10-2018 TSC_c01890 197fa89c59815b5f683dee1603c4b59a 163 Pfam PF00694 Aconitase C-terminal domain 47 103 2.1E-18 T 12-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 TSC_c01380 5d9eb7dd90ec6859a042c45b5aea97cb 429 SUPERFAMILY SSF53850 34 407 1.45E-69 T 12-10-2018 TSC_c01380 5d9eb7dd90ec6859a042c45b5aea97cb 429 Gene3D G3DSA:3.40.190.10 146 419 1.9E-89 T 12-10-2018 TSC_c01380 5d9eb7dd90ec6859a042c45b5aea97cb 429 Pfam PF13416 Bacterial extracellular solute-binding protein 51 362 1.1E-27 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSC_c01380 5d9eb7dd90ec6859a042c45b5aea97cb 429 Gene3D G3DSA:3.40.190.10 58 379 1.9E-89 T 12-10-2018 TSC_c02850 f6e9718edd46357e859ec0c0c47dddea 368 Pfam PF03739 Predicted permease YjgP/YjgQ family 5 365 5.1E-56 T 12-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 TSC_c23280 2292f651d80b52c745fda082afaa1d40 189 Pfam PF01904 Protein of unknown function DUF72 16 118 3.2E-8 T 12-10-2018 IPR002763 Protein of unknown function DUF72 TSC_c23280 2292f651d80b52c745fda082afaa1d40 189 Gene3D G3DSA:3.20.20.410 9 143 1.3E-7 T 12-10-2018 IPR036520 UPF0759 superfamily TSC_c23280 2292f651d80b52c745fda082afaa1d40 189 SUPERFAMILY SSF117396 12 143 1.57E-9 T 12-10-2018 IPR036520 UPF0759 superfamily TSC_c12450 1d45d2e3e654a0e73f68bf199b17ae52 324 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 137 243 3.8E-22 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TSC_c12450 1d45d2e3e654a0e73f68bf199b17ae52 324 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 11 288 18.607 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TSC_c12450 1d45d2e3e654a0e73f68bf199b17ae52 324 Gene3D G3DSA:1.20.120.920 98 293 4.0E-69 T 12-10-2018 TSC_c12450 1d45d2e3e654a0e73f68bf199b17ae52 324 Pfam PF01867 CRISPR associated protein Cas1 128 231 6.5E-9 T 12-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 TSC_c12450 1d45d2e3e654a0e73f68bf199b17ae52 324 Gene3D G3DSA:3.100.10.20 8 97 6.5E-25 T 12-10-2018 TSC_c12450 1d45d2e3e654a0e73f68bf199b17ae52 324 TIGRFAM TIGR03638 cas1_ECOLI: CRISPR-associated endonuclease Cas1, subtype I-E/ECOLI 11 276 1.2E-107 T 12-10-2018 IPR019851 CRISPR-associated protein Cas1, ECOLI subtype GO:0004520|GO:0043571|GO:0046872 TSC_c23120 101c8135429804464624485349501565 211 Pfam PF00753 Metallo-beta-lactamase superfamily 9 188 3.8E-31 T 12-10-2018 IPR001279 Metallo-beta-lactamase TSC_c23120 101c8135429804464624485349501565 211 Gene3D G3DSA:3.60.15.10 1 211 1.2E-79 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c23120 101c8135429804464624485349501565 211 SUPERFAMILY SSF56281 10 201 1.44E-52 T 12-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like TSC_c23120 101c8135429804464624485349501565 211 SMART SM00849 12 188 2.9E-39 T 12-10-2018 IPR001279 Metallo-beta-lactamase TSC_c20830 7800cd51bb2959d216e07563e6d54dc7 252 Gene3D G3DSA:3.30.1600.10 30 165 8.5E-78 T 12-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily TSC_c20830 7800cd51bb2959d216e07563e6d54dc7 252 Gene3D G3DSA:3.40.50.1220 12 237 8.5E-78 T 12-10-2018 TSC_c20830 7800cd51bb2959d216e07563e6d54dc7 252 SUPERFAMILY SSF52467 3 239 2.62E-81 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSC_c20830 7800cd51bb2959d216e07563e6d54dc7 252 Pfam PF02146 Sir2 family 21 195 3.1E-44 T 12-10-2018 IPR003000 Sirtuin family GO:0070403 TSC_c20830 7800cd51bb2959d216e07563e6d54dc7 252 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 14 246 58.016 T 12-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 TSC_c15680 23c15f59197911c9159a40b169313004 102 Pfam PF01863 Protein of unknown function DUF45 16 98 9.8E-25 T 12-10-2018 IPR002725 Protein of unknown function DUF45 TSC_c15680 23c15f59197911c9159a40b169313004 102 Gene3D G3DSA:3.30.2010.10 10 102 1.6E-16 T 12-10-2018 TSC_c18940 a595cd7b753669175fb3b869c9fe1d27 422 Pfam PF01336 OB-fold nucleic acid binding domain 24 85 1.4E-8 T 12-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 TSC_c18940 a595cd7b753669175fb3b869c9fe1d27 422 SUPERFAMILY SSF50249 4 93 2.2E-21 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c18940 a595cd7b753669175fb3b869c9fe1d27 422 Gene3D G3DSA:3.30.930.10 93 411 2.1E-122 T 12-10-2018 TSC_c18940 a595cd7b753669175fb3b869c9fe1d27 422 SUPERFAMILY SSF55681 91 421 3.98E-80 T 12-10-2018 TSC_c18940 a595cd7b753669175fb3b869c9fe1d27 422 Pfam PF00152 tRNA synthetases class II (D, K and N) 106 416 1.7E-80 T 12-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c18940 a595cd7b753669175fb3b869c9fe1d27 422 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 12 422 3.4E-120 T 12-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSC_c18940 a595cd7b753669175fb3b869c9fe1d27 422 Gene3D G3DSA:2.40.50.140 1 92 1.5E-25 T 12-10-2018 TSC_c18940 a595cd7b753669175fb3b869c9fe1d27 422 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 204 9.4E-22 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c18940 a595cd7b753669175fb3b869c9fe1d27 422 PRINTS PR01042 Aspartyl-tRNA synthetase signature 377 391 9.4E-22 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c18940 a595cd7b753669175fb3b869c9fe1d27 422 PRINTS PR01042 Aspartyl-tRNA synthetase signature 337 353 9.4E-22 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c18940 a595cd7b753669175fb3b869c9fe1d27 422 PRINTS PR01042 Aspartyl-tRNA synthetase signature 175 187 9.4E-22 T 12-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c18940 a595cd7b753669175fb3b869c9fe1d27 422 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 1 422 39.48 T 12-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSC_c11310 2eaf3bd3d387e9ae75b980af73451077 304 Gene3D G3DSA:1.25.40.10 216 302 2.0E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c11310 2eaf3bd3d387e9ae75b980af73451077 304 SUPERFAMILY SSF48452 239 293 5.69E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c11310 2eaf3bd3d387e9ae75b980af73451077 304 SUPERFAMILY SSF54001 104 202 3.6E-6 T 12-10-2018 IPR038765 Papain-like cysteine peptidase superfamily TSC_c06780 68303b6440ebc29aa067ccc809fa6f65 633 SUPERFAMILY SSF140356 6 72 7.59E-19 T 12-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 TSC_c06780 68303b6440ebc29aa067ccc809fa6f65 633 Gene3D G3DSA:3.30.1840.10 4 265 1.6E-28 T 12-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 TSC_c06780 68303b6440ebc29aa067ccc809fa6f65 633 Gene3D G3DSA:3.30.870.10 282 444 1.8E-41 T 12-10-2018 TSC_c06780 68303b6440ebc29aa067ccc809fa6f65 633 SUPERFAMILY SSF56024 288 439 1.28E-31 T 12-10-2018 TSC_c06780 68303b6440ebc29aa067ccc809fa6f65 633 SUPERFAMILY SSF56024 481 626 6.06E-35 T 12-10-2018 TSC_c06780 68303b6440ebc29aa067ccc809fa6f65 633 Pfam PF13089 Polyphosphate kinase N-terminal domain 6 54 2.2E-17 T 12-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 TSC_c06780 68303b6440ebc29aa067ccc809fa6f65 633 Pfam PF02503 Polyphosphate kinase middle domain 142 278 4.7E-9 T 12-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 TSC_c06780 68303b6440ebc29aa067ccc809fa6f65 633 Pfam PF13090 Polyphosphate kinase C-terminal domain 287 620 1.6E-77 T 12-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 TSC_c06780 68303b6440ebc29aa067ccc809fa6f65 633 SUPERFAMILY SSF143724 93 270 1.88E-14 T 12-10-2018 TSC_c06780 68303b6440ebc29aa067ccc809fa6f65 633 Gene3D G3DSA:3.30.870.10 476 631 7.1E-38 T 12-10-2018 TSC_c14400 a16713c641ecf1656792461914a47eec 71 SUPERFAMILY SSF143800 2 64 5.1E-25 T 12-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c14400 a16713c641ecf1656792461914a47eec 71 ProSitePatterns PS01143 Ribosomal protein L31 signature. 34 55 - T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c14400 a16713c641ecf1656792461914a47eec 71 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 64 3.6E-26 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c14400 a16713c641ecf1656792461914a47eec 71 PRINTS PR01249 Ribosomal protein L31 signature 2 19 1.8E-21 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c14400 a16713c641ecf1656792461914a47eec 71 PRINTS PR01249 Ribosomal protein L31 signature 30 45 1.8E-21 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c14400 a16713c641ecf1656792461914a47eec 71 PRINTS PR01249 Ribosomal protein L31 signature 45 63 1.8E-21 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c14400 a16713c641ecf1656792461914a47eec 71 Pfam PF01197 Ribosomal protein L31 2 64 2.0E-29 T 12-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c14400 a16713c641ecf1656792461914a47eec 71 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 67 28.378 T 12-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c14400 a16713c641ecf1656792461914a47eec 71 Gene3D G3DSA:2.30.170.50 1 68 1.4E-29 T 12-10-2018 TSC_c14720 6332cdb6d8b48e261f42678b50301406 223 Gene3D G3DSA:2.30.30.90 148 222 1.0E-6 T 12-10-2018 IPR038157 Ferrous iron transporter, core domain TSC_c14720 6332cdb6d8b48e261f42678b50301406 223 SUPERFAMILY SSF47979 68 141 6.67E-27 T 12-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 TSC_c14720 6332cdb6d8b48e261f42678b50301406 223 Pfam PF04023 FeoA domain 149 216 1.2E-8 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TSC_c14720 6332cdb6d8b48e261f42678b50301406 223 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 68 136 1.1E-29 T 12-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 TSC_c14720 6332cdb6d8b48e261f42678b50301406 223 Gene3D G3DSA:1.10.10.10 5 141 5.8E-54 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c14720 6332cdb6d8b48e261f42678b50301406 223 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 6 65 4.0E-18 T 12-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 TSC_c14720 6332cdb6d8b48e261f42678b50301406 223 SMART SM00899 148 217 2.6E-8 T 12-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 TSC_c14720 6332cdb6d8b48e261f42678b50301406 223 SUPERFAMILY SSF46785 6 66 4.37E-13 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c14720 6332cdb6d8b48e261f42678b50301406 223 SMART SM00529 29 128 5.5E-48 T 12-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 TSC_c14720 6332cdb6d8b48e261f42678b50301406 223 SUPERFAMILY SSF50037 133 216 2.98E-10 T 12-10-2018 IPR008988 Transcriptional repressor, C-terminal TSC_c01580 6a29dd88b5b742af3854af43ed12ae68 241 Gene3D G3DSA:3.60.140.10 3 240 9.3E-78 T 12-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily TSC_c01580 6a29dd88b5b742af3854af43ed12ae68 241 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 16 238 1.1E-67 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase TSC_c01580 6a29dd88b5b742af3854af43ed12ae68 241 SUPERFAMILY SSF64438 6 239 3.66E-75 T 12-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic TSC_c01580 6a29dd88b5b742af3854af43ed12ae68 241 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 21 239 3.5E-51 T 12-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase TSC_c15990 35c52fdc6ba7009c73a254061a587695 340 Gene3D G3DSA:3.70.10.10 114 317 2.6E-27 T 12-10-2018 TSC_c15990 35c52fdc6ba7009c73a254061a587695 340 SMART SM00480 11 329 1.3E-4 T 12-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 TSC_c15990 35c52fdc6ba7009c73a254061a587695 340 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 215 318 8.5E-10 T 12-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 TSC_c15990 35c52fdc6ba7009c73a254061a587695 340 SUPERFAMILY SSF55979 126 213 1.04E-5 T 12-10-2018 TSC_c15990 35c52fdc6ba7009c73a254061a587695 340 SUPERFAMILY SSF55979 216 319 2.23E-9 T 12-10-2018 TSC_c15990 35c52fdc6ba7009c73a254061a587695 340 Gene3D G3DSA:3.10.150.10 51 205 2.6E-27 T 12-10-2018 TSC_c00090 9c1170f3544f2fa6484770b4c763fccc 310 SUPERFAMILY SSF81606 5 236 2.49E-66 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSC_c00090 9c1170f3544f2fa6484770b4c763fccc 310 SMART SM00331 10 236 3.7E-41 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSC_c00090 9c1170f3544f2fa6484770b4c763fccc 310 Gene3D G3DSA:3.60.40.10 2 238 4.9E-69 T 12-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSC_c00090 9c1170f3544f2fa6484770b4c763fccc 310 Pfam PF13672 Protein phosphatase 2C 18 211 1.1E-19 T 12-10-2018 TSC_c00090 9c1170f3544f2fa6484770b4c763fccc 310 SMART SM00332 1 234 8.8E-38 T 12-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 TSC_c17850 2d9f72263f0bea92898ba9ad425a165c 242 Gene3D G3DSA:3.40.50.300 1 231 4.1E-66 T 12-10-2018 TSC_c17850 2d9f72263f0bea92898ba9ad425a165c 242 Pfam PF00005 ABC transporter 20 166 2.6E-34 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c17850 2d9f72263f0bea92898ba9ad425a165c 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c17850 2d9f72263f0bea92898ba9ad425a165c 242 SUPERFAMILY SSF52540 2 223 1.13E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c17850 2d9f72263f0bea92898ba9ad425a165c 242 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 215 9.0E-81 T 12-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 TSC_c17850 2d9f72263f0bea92898ba9ad425a165c 242 SMART SM00382 28 214 6.3E-15 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c21090 b9a5431843dda6f12f8a1b2f9e4d492a 260 TIGRFAM TIGR04484 thiosulf_SoxA: sulfur oxidation c-type cytochrome SoxA 45 258 1.0E-67 T 12-10-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 TSC_c21090 b9a5431843dda6f12f8a1b2f9e4d492a 260 Gene3D G3DSA:1.10.760.10 47 136 4.3E-22 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c21090 b9a5431843dda6f12f8a1b2f9e4d492a 260 Gene3D G3DSA:1.10.760.10 137 260 6.0E-27 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c21090 b9a5431843dda6f12f8a1b2f9e4d492a 260 PIRSF PIRSF038455 4 260 2.6E-72 T 12-10-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 TSC_c21090 b9a5431843dda6f12f8a1b2f9e4d492a 260 SUPERFAMILY SSF46626 146 253 1.15E-27 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c21090 b9a5431843dda6f12f8a1b2f9e4d492a 260 SUPERFAMILY SSF46626 45 141 1.34E-21 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c06080 3efd4f211b1087ed781295a1b3bf5740 214 Pfam PF04098 Rad52/22 family double-strand break repair protein 4 133 7.8E-17 T 12-10-2018 IPR007232 DNA repair protein Rad52/59/22 GO:0006281|GO:0006310 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938 TSC_c19320 7ce9fa228e1545f7f7865fda0d35c3d8 221 SUPERFAMILY SSF53167 2 211 9.3E-47 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TSC_c19320 7ce9fa228e1545f7f7865fda0d35c3d8 221 Gene3D G3DSA:3.40.50.1580 1 221 1.3E-47 T 12-10-2018 TSC_c19320 7ce9fa228e1545f7f7865fda0d35c3d8 221 Pfam PF01048 Phosphorylase superfamily 35 220 8.6E-37 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TSC_c19320 7ce9fa228e1545f7f7865fda0d35c3d8 221 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 36 215 5.1E-28 T 12-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 TSC_c00560 325ffde28b175d015443b382f0b59eea 196 Gene3D G3DSA:3.40.30.10 26 196 4.0E-58 T 12-10-2018 TSC_c00560 325ffde28b175d015443b382f0b59eea 196 SUPERFAMILY SSF52833 40 195 1.17E-45 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TSC_c00560 325ffde28b175d015443b382f0b59eea 196 Pfam PF02630 SCO1/SenC 41 175 2.2E-39 T 12-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c05030 f3c3a8bc9706ffce8f96ee51f9a896d7 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 334 4.1E-49 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c05030 f3c3a8bc9706ffce8f96ee51f9a896d7 336 SUPERFAMILY SSF161098 95 320 1.64E-22 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c19430 5f07685e5b562a094bea507ccf9ad56c 106 SUPERFAMILY SSF109854 1 106 2.29E-16 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TSC_c19430 5f07685e5b562a094bea507ccf9ad56c 106 Gene3D G3DSA:1.20.120.450 1 106 7.3E-15 T 12-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes TSC_c19430 5f07685e5b562a094bea507ccf9ad56c 106 Pfam PF07609 Protein of unknown function (DUF1572) 25 105 4.4E-7 T 12-10-2018 IPR011466 Protein of unknown function DUF1572 TSC_c03910 089b886a46fb90481c72c6848d45ed35 468 SUPERFAMILY SSF101960 35 465 3.4E-136 T 12-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TSC_c03910 089b886a46fb90481c72c6848d45ed35 468 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 12 459 4.6E-214 T 12-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 TSC_c03910 089b886a46fb90481c72c6848d45ed35 468 Pfam PF01458 Uncharacterized protein family (UPF0051) 214 439 6.1E-73 T 12-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TSC_c17420 b2c5b498866f51b0b87ded24ee80135a 278 Pfam PF11563 Protoglobin 18 143 8.9E-10 T 12-10-2018 TSC_c17420 b2c5b498866f51b0b87ded24ee80135a 278 SUPERFAMILY SSF54285 240 276 3.4E-5 T 12-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp TSC_c17420 b2c5b498866f51b0b87ded24ee80135a 278 Gene3D G3DSA:3.10.20.30 178 277 3.7E-12 T 12-10-2018 IPR012675 Beta-grasp domain superfamily TSC_c17420 b2c5b498866f51b0b87ded24ee80135a 278 SUPERFAMILY SSF46458 10 146 3.88E-7 T 12-10-2018 IPR009050 Globin-like superfamily TSC_c17420 b2c5b498866f51b0b87ded24ee80135a 278 Gene3D G3DSA:1.10.490.10 19 170 4.6E-11 T 12-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 TSC_c08820 375964e8770d2eb2c5acbb8ec865f78b 250 Gene3D G3DSA:3.40.50.1820 40 206 9.5E-12 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c08820 375964e8770d2eb2c5acbb8ec865f78b 250 SUPERFAMILY SSF53474 61 209 4.63E-15 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c08820 375964e8770d2eb2c5acbb8ec865f78b 250 Pfam PF12695 Alpha/beta hydrolase family 67 224 6.0E-51 T 12-10-2018 IPR029059 Alpha/beta hydrolase fold-5 TSC_c09360 c1a23c889cb904c664e1da65b3206540 422 Pfam PF00574 Clp protease 19 118 8.5E-6 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TSC_c09360 c1a23c889cb904c664e1da65b3206540 422 SUPERFAMILY SSF52096 13 188 2.49E-23 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSC_c09360 c1a23c889cb904c664e1da65b3206540 422 Gene3D G3DSA:3.90.226.10 16 226 4.1E-46 T 12-10-2018 TSC_c09360 c1a23c889cb904c664e1da65b3206540 422 Pfam PF01957 NfeD-like C-terminal, partner-binding 278 418 6.0E-11 T 12-10-2018 IPR002810 NfeD-like, C-terminal domain TSC_p800080 2fc7ddbee705b65770ef79d42734107d 114 Gene3D G3DSA:3.30.460.10 7 103 1.1E-10 T 12-10-2018 TSC_p800080 2fc7ddbee705b65770ef79d42734107d 114 Pfam PF01909 Nucleotidyltransferase domain 30 56 5.3E-7 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSC_p800080 2fc7ddbee705b65770ef79d42734107d 114 SUPERFAMILY SSF81301 9 110 8.65E-15 T 12-10-2018 TSC_c14740 9a79dda9c7fc425320186bd3e4d61dbc 245 Gene3D G3DSA:3.40.50.720 1 245 2.8E-88 T 12-10-2018 TSC_c14740 9a79dda9c7fc425320186bd3e4d61dbc 245 SUPERFAMILY SSF51735 4 240 6.33E-82 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c14740 9a79dda9c7fc425320186bd3e4d61dbc 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 179 5.7E-7 T 12-10-2018 TSC_c14740 9a79dda9c7fc425320186bd3e4d61dbc 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 4.0E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c14740 9a79dda9c7fc425320186bd3e4d61dbc 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 4.0E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c14740 9a79dda9c7fc425320186bd3e4d61dbc 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 4.0E-8 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c14740 9a79dda9c7fc425320186bd3e4d61dbc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c14740 9a79dda9c7fc425320186bd3e4d61dbc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 5.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c14740 9a79dda9c7fc425320186bd3e4d61dbc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 5.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c14740 9a79dda9c7fc425320186bd3e4d61dbc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 5.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c14740 9a79dda9c7fc425320186bd3e4d61dbc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 5.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c14740 9a79dda9c7fc425320186bd3e4d61dbc 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 202 222 5.7E-40 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c14740 9a79dda9c7fc425320186bd3e4d61dbc 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSC_c14740 9a79dda9c7fc425320186bd3e4d61dbc 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 238 4.9E-68 T 12-10-2018 TSC_c23140 355de251f86ceaa025dc6a24dad7b6f3 142 Gene3D G3DSA:3.30.300.20 1 142 1.3E-42 T 12-10-2018 IPR015946 K homology domain-like, alpha/beta TSC_c23140 355de251f86ceaa025dc6a24dad7b6f3 142 Pfam PF02566 OsmC-like protein 40 137 1.6E-19 T 12-10-2018 IPR003718 OsmC/Ohr family TSC_c23140 355de251f86ceaa025dc6a24dad7b6f3 142 SUPERFAMILY SSF82784 3 138 4.32E-38 T 12-10-2018 IPR036102 OsmC/Ohr superfamily TSC_c23140 355de251f86ceaa025dc6a24dad7b6f3 142 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 4 139 2.0E-54 T 12-10-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 TSC_c00980 f89d54f7dd3a6dc17114287cdf072605 195 SUPERFAMILY SSF81452 25 194 6.8E-32 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00980 f89d54f7dd3a6dc17114287cdf072605 195 Gene3D G3DSA:1.20.120.80 34 195 2.2E-27 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c03780 661582a8af1637b2872c2f3d2c8d6a8c 269 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 92 260 3.5E-7 T 12-10-2018 IPR039447 Urease accessory protein UreH-like, transmembrane domain TSC_c02390 5e3ed60fc32bb8bc05f4fdfa6f01c340 324 SMART SM00861 4 179 4.0E-76 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSC_c02390 5e3ed60fc32bb8bc05f4fdfa6f01c340 324 Gene3D G3DSA:3.40.50.920 193 324 3.4E-46 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSC_c02390 5e3ed60fc32bb8bc05f4fdfa6f01c340 324 Gene3D G3DSA:3.40.50.970 1 192 1.7E-96 T 12-10-2018 TSC_c02390 5e3ed60fc32bb8bc05f4fdfa6f01c340 324 SUPERFAMILY SSF52518 2 204 2.14E-74 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c02390 5e3ed60fc32bb8bc05f4fdfa6f01c340 324 SUPERFAMILY SSF52922 188 323 7.46E-41 T 12-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 TSC_c02390 5e3ed60fc32bb8bc05f4fdfa6f01c340 324 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 1.1E-51 T 12-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain TSC_c02390 5e3ed60fc32bb8bc05f4fdfa6f01c340 324 Pfam PF02780 Transketolase, C-terminal domain 194 313 8.1E-35 T 12-10-2018 IPR033248 Transketolase, C-terminal domain TSC_c12200 43c97acdcd7f12d098e2e96bbbc569cd 129 Pfam PF01638 HxlR-like helix-turn-helix 38 125 5.2E-22 T 12-10-2018 IPR002577 Helix-turn-helix, HxlR type TSC_c12200 43c97acdcd7f12d098e2e96bbbc569cd 129 SMART SM00418 34 118 0.0028 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c12200 43c97acdcd7f12d098e2e96bbbc569cd 129 Gene3D G3DSA:1.10.10.10 23 128 4.4E-34 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c12200 43c97acdcd7f12d098e2e96bbbc569cd 129 SUPERFAMILY SSF46785 26 125 1.81E-29 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c12580 7649f17da1203b81f67c80b3f923c553 97 SUPERFAMILY SSF81301 3 93 1.26E-23 T 12-10-2018 TSC_c12580 7649f17da1203b81f67c80b3f923c553 97 Pfam PF01909 Nucleotidyltransferase domain 14 92 3.5E-15 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSC_c12580 7649f17da1203b81f67c80b3f923c553 97 Gene3D G3DSA:3.30.460.10 7 96 1.5E-22 T 12-10-2018 TSC_c14810 0840ec10e2e7fbfcf471bd9329eddfcf 411 Pfam PF01547 Bacterial extracellular solute-binding protein 33 325 1.6E-28 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSC_c14810 0840ec10e2e7fbfcf471bd9329eddfcf 411 Gene3D G3DSA:3.40.190.10 24 366 7.2E-161 T 12-10-2018 TSC_c14810 0840ec10e2e7fbfcf471bd9329eddfcf 411 SUPERFAMILY SSF53850 18 409 3.88E-63 T 12-10-2018 TSC_c14810 0840ec10e2e7fbfcf471bd9329eddfcf 411 Gene3D G3DSA:3.40.190.10 141 389 7.2E-161 T 12-10-2018 TSC_c03650 12c815ca8f421001c6030f884421642d 183 TIGRFAM TIGR01367 pyrE_Therm: orotate phosphoribosyltransferase 2 182 4.5E-66 T 12-10-2018 IPR006273 Orotate phosphoribosyltransferase, bacterial GO:0004588|GO:0019856 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 TSC_c03650 12c815ca8f421001c6030f884421642d 183 SUPERFAMILY SSF53271 2 174 2.98E-32 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TSC_c03650 12c815ca8f421001c6030f884421642d 183 Gene3D G3DSA:3.40.50.2020 1 182 6.9E-53 T 12-10-2018 TSC_c03650 12c815ca8f421001c6030f884421642d 183 Pfam PF00156 Phosphoribosyl transferase domain 33 150 3.0E-12 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSC_c03650 12c815ca8f421001c6030f884421642d 183 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 183 23.431 T 12-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 TSC_c05360 e3484177ceb5eb95c1184aa9ecaa2215 130 Pfam PF05168 HEPN domain 10 125 2.8E-25 T 12-10-2018 IPR007842 HEPN domain TSC_c05360 e3484177ceb5eb95c1184aa9ecaa2215 130 SUPERFAMILY SSF81593 8 126 9.02E-25 T 12-10-2018 TSC_c05360 e3484177ceb5eb95c1184aa9ecaa2215 130 Gene3D G3DSA:1.20.120.330 4 129 3.2E-30 T 12-10-2018 TSC_c05360 e3484177ceb5eb95c1184aa9ecaa2215 130 SMART SM00748 12 126 5.9E-12 T 12-10-2018 IPR007842 HEPN domain TSC_c09690 f14f0601e197c605278885c50ecbd319 168 SUPERFAMILY SSF49503 42 167 1.82E-33 T 12-10-2018 IPR008972 Cupredoxin TSC_c09690 f14f0601e197c605278885c50ecbd319 168 Gene3D G3DSA:1.20.1070.10 1 46 1.3E-27 T 12-10-2018 TSC_c09690 f14f0601e197c605278885c50ecbd319 168 Pfam PF09125 Cytochrome C oxidase subunit II, transmembrane 3 40 4.7E-24 T 12-10-2018 IPR015209 Cytochrome C oxidase subunit IIa, transmembrane domain KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 TSC_c09690 f14f0601e197c605278885c50ecbd319 168 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 93 161 5.6E-9 T 12-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c09690 f14f0601e197c605278885c50ecbd319 168 Gene3D G3DSA:2.60.40.420 56 167 7.2E-30 T 12-10-2018 IPR008972 Cupredoxin TSC_c09690 f14f0601e197c605278885c50ecbd319 168 SUPERFAMILY SSF81464 3 40 1.05E-17 T 12-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c09690 f14f0601e197c605278885c50ecbd319 168 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 112 160 - T 12-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c21920 5202f200851049f7416557d988cdf919 99 SMART SM01409 8 75 3.0E-8 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSC_c21920 5202f200851049f7416557d988cdf919 99 SUPERFAMILY SSF63562 1 96 1.01E-20 T 12-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSC_c21920 5202f200851049f7416557d988cdf919 99 Pfam PF01192 RNA polymerase Rpb6 12 72 1.0E-7 T 12-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSC_c21920 5202f200851049f7416557d988cdf919 99 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 48 2.0E-8 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c21920 5202f200851049f7416557d988cdf919 99 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 76 13.459 T 12-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c21920 5202f200851049f7416557d988cdf919 99 Gene3D G3DSA:3.90.940.10 1 99 6.0E-58 T 12-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 TSC_c20780 60882684bc057263be7cd93ed7d82c96 121 Pfam PF09685 Domain of unknown function (DUF4870) 11 120 5.1E-22 T 12-10-2018 IPR019109 Protein of unknown function DUF4870 TSC_c14110 a83806581bd8c136734ac3c5a2e4849a 109 Pfam PF06153 Cyclic-di-AMP receptor 1 109 2.0E-48 T 12-10-2018 IPR010375 Cyclic-di-AMP receptor TSC_c14110 a83806581bd8c136734ac3c5a2e4849a 109 Gene3D G3DSA:3.30.70.120 1 103 1.1E-39 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TSC_c14110 a83806581bd8c136734ac3c5a2e4849a 109 SUPERFAMILY SSF54913 1 109 4.2E-16 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TSC_c02450 934bf0f885a2eeccd949df2663602d8b 267 Gene3D G3DSA:1.10.8.900 151 252 4.6E-84 T 12-10-2018 TSC_c02450 934bf0f885a2eeccd949df2663602d8b 267 Gene3D G3DSA:3.40.50.150 13 254 4.6E-84 T 12-10-2018 TSC_c02450 934bf0f885a2eeccd949df2663602d8b 267 SUPERFAMILY SSF53335 13 246 1.46E-33 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c02450 934bf0f885a2eeccd949df2663602d8b 267 Pfam PF08241 Methyltransferase domain 48 141 2.5E-20 T 12-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 TSC_c04960 957f1252d3f0a86eacd24f09c650b93a 327 SUPERFAMILY SSF55031 133 242 1.14E-16 T 12-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain TSC_c04960 957f1252d3f0a86eacd24f09c650b93a 327 Pfam PF01546 Peptidase family M20/M25/M40 43 322 1.7E-14 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 TSC_c04960 957f1252d3f0a86eacd24f09c650b93a 327 Pfam PF07687 Peptidase dimerisation domain 133 229 3.7E-10 T 12-10-2018 IPR011650 Peptidase M20, dimerisation domain TSC_c04960 957f1252d3f0a86eacd24f09c650b93a 327 Gene3D G3DSA:3.30.70.360 137 243 7.8E-18 T 12-10-2018 TSC_c04960 957f1252d3f0a86eacd24f09c650b93a 327 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 42 51 - T 12-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 TSC_c04960 957f1252d3f0a86eacd24f09c650b93a 327 SUPERFAMILY SSF53187 26 324 1.45E-31 T 12-10-2018 TSC_c08740 e458e1a00104d731d43d41a47d33c1de 99 Pfam PF00137 ATP synthase subunit C 36 95 3.4E-16 T 12-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 TSC_c08740 e458e1a00104d731d43d41a47d33c1de 99 Gene3D G3DSA:1.20.120.610 4 97 6.7E-16 T 12-10-2018 TSC_c08740 e458e1a00104d731d43d41a47d33c1de 99 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 1 16 3.6E-8 T 12-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c08740 e458e1a00104d731d43d41a47d33c1de 99 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 74 97 3.6E-8 T 12-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c08740 e458e1a00104d731d43d41a47d33c1de 99 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 47 73 3.6E-8 T 12-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 TSC_c08740 e458e1a00104d731d43d41a47d33c1de 99 SUPERFAMILY SSF81333 31 96 2.22E-13 T 12-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily TSC_c23870 94efd90f1f8c0083fd5321f218f51993 127 SUPERFAMILY SSF54593 5 119 1.83E-6 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c19260 30f67f38f1bcb8b4460da38904aed1e8 417 Pfam PF13347 MFS/sugar transport protein 6 412 1.1E-67 T 12-10-2018 TSC_c19260 30f67f38f1bcb8b4460da38904aed1e8 417 Gene3D G3DSA:1.20.1250.20 205 414 1.3E-17 T 12-10-2018 TSC_c19260 30f67f38f1bcb8b4460da38904aed1e8 417 SUPERFAMILY SSF103473 6 413 1.29E-39 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c19260 30f67f38f1bcb8b4460da38904aed1e8 417 ProSitePatterns PS00872 Sodium:galactoside symporter family signature. 54 78 - T 12-10-2018 IPR018043 Sodium:galactoside symporter, conserved site GO:0005215|GO:0006814|GO:0016020 TSC_c19260 30f67f38f1bcb8b4460da38904aed1e8 417 Gene3D G3DSA:1.20.1250.20 2 198 8.3E-17 T 12-10-2018 TSC_c08890 0d9e0e491bd0a4492681141d3737e734 116 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 88 5.2E-11 T 12-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain TSC_c08890 0d9e0e491bd0a4492681141d3737e734 116 Gene3D G3DSA:3.40.140.10 2 116 7.9E-35 T 12-10-2018 TSC_c08890 0d9e0e491bd0a4492681141d3737e734 116 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 3 115 8.9E-35 T 12-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 TSC_c08890 0d9e0e491bd0a4492681141d3737e734 116 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 44 83 - T 12-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 TSC_c08890 0d9e0e491bd0a4492681141d3737e734 116 SUPERFAMILY SSF53927 3 115 2.81E-33 T 12-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 TSC_c10730 57e1b74d76bd58b277f82c926fe3fa1b 263 Gene3D G3DSA:3.40.50.720 2 259 1.3E-79 T 12-10-2018 TSC_c10730 57e1b74d76bd58b277f82c926fe3fa1b 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 1.0E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c10730 57e1b74d76bd58b277f82c926fe3fa1b 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 1.0E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c10730 57e1b74d76bd58b277f82c926fe3fa1b 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.0E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c10730 57e1b74d76bd58b277f82c926fe3fa1b 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 1.0E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c10730 57e1b74d76bd58b277f82c926fe3fa1b 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.0E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c10730 57e1b74d76bd58b277f82c926fe3fa1b 263 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.0E-36 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c10730 57e1b74d76bd58b277f82c926fe3fa1b 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 2.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c10730 57e1b74d76bd58b277f82c926fe3fa1b 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 2.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c10730 57e1b74d76bd58b277f82c926fe3fa1b 263 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 2.0E-5 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c10730 57e1b74d76bd58b277f82c926fe3fa1b 263 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 12-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 TSC_c10730 57e1b74d76bd58b277f82c926fe3fa1b 263 SUPERFAMILY SSF51735 11 254 4.28E-80 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c10730 57e1b74d76bd58b277f82c926fe3fa1b 263 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 253 7.5E-68 T 12-10-2018 TSC_c10730 57e1b74d76bd58b277f82c926fe3fa1b 263 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 12 191 9.2E-4 T 12-10-2018 TSC_c20370 9d1a4060b724f0460cfeb33bb82f8c43 148 SUPERFAMILY SSF47113 1 148 1.19E-53 T 12-10-2018 IPR009072 Histone-fold GO:0046982 TSC_c20370 9d1a4060b724f0460cfeb33bb82f8c43 148 Pfam PF09123 Domain of unknown function (DUF1931) 8 145 2.6E-56 T 12-10-2018 IPR015207 Protein of unknown function DUF1931 TSC_c20370 9d1a4060b724f0460cfeb33bb82f8c43 148 Gene3D G3DSA:1.10.20.10 1 148 1.4E-62 T 12-10-2018 IPR009072 Histone-fold GO:0046982 TSC_c12070 a774e5194dd9122ed85455ba59a43e21 325 Gene3D G3DSA:3.40.50.2300 60 297 4.6E-55 T 12-10-2018 TSC_c12070 a774e5194dd9122ed85455ba59a43e21 325 SUPERFAMILY SSF47413 5 64 1.53E-18 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSC_c12070 a774e5194dd9122ed85455ba59a43e21 325 SUPERFAMILY SSF53822 77 321 1.73E-54 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TSC_c12070 a774e5194dd9122ed85455ba59a43e21 325 Gene3D G3DSA:1.10.260.40 1 59 3.8E-23 T 12-10-2018 TSC_c12070 a774e5194dd9122ed85455ba59a43e21 325 ProSitePatterns PS00356 LacI-type HTH domain signature. 9 27 - T 12-10-2018 TSC_c12070 a774e5194dd9122ed85455ba59a43e21 325 Gene3D G3DSA:3.40.50.2300 155 281 4.6E-55 T 12-10-2018 TSC_c12070 a774e5194dd9122ed85455ba59a43e21 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 53 3.3E-18 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSC_c12070 a774e5194dd9122ed85455ba59a43e21 325 SMART SM00354 6 76 9.3E-23 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSC_c12070 a774e5194dd9122ed85455ba59a43e21 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 18 28 2.7E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSC_c12070 a774e5194dd9122ed85455ba59a43e21 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 8 18 2.7E-5 T 12-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 TSC_c12070 a774e5194dd9122ed85455ba59a43e21 325 Pfam PF13377 Periplasmic binding protein-like domain 163 319 1.5E-31 T 12-10-2018 TSC_c10940 577c5aec48ed851e1c4f1e9996fb5a57 228 Pfam PF07722 Peptidase C26 3 214 5.6E-61 T 12-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 TSC_c10940 577c5aec48ed851e1c4f1e9996fb5a57 228 SUPERFAMILY SSF52317 21 220 3.67E-41 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c10940 577c5aec48ed851e1c4f1e9996fb5a57 228 Gene3D G3DSA:3.40.50.880 2 225 2.3E-73 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c15490 e038afd7d23a9a0dcdb621fb9173dd19 360 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 41 328 1.3E-47 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSC_c15490 e038afd7d23a9a0dcdb621fb9173dd19 360 PIRSF PIRSF039026 3 359 3.9E-111 T 12-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like TSC_c15490 e038afd7d23a9a0dcdb621fb9173dd19 360 Gene3D G3DSA:3.40.190.170 32 360 2.2E-137 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSC_c15490 e038afd7d23a9a0dcdb621fb9173dd19 360 SUPERFAMILY SSF53850 135 223 3.8E-5 T 12-10-2018 TSC_c03380 d69f7c8bc8b67e6da52af7e5448242a8 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.0E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSC_c03380 d69f7c8bc8b67e6da52af7e5448242a8 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.0E-8 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSC_c03380 d69f7c8bc8b67e6da52af7e5448242a8 186 Gene3D G3DSA:1.10.357.10 1 186 4.5E-73 T 12-10-2018 TSC_c03380 d69f7c8bc8b67e6da52af7e5448242a8 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 1.4E-13 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSC_c03380 d69f7c8bc8b67e6da52af7e5448242a8 186 SUPERFAMILY SSF48498 87 184 3.06E-9 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSC_c03380 d69f7c8bc8b67e6da52af7e5448242a8 186 SUPERFAMILY SSF46689 4 83 3.59E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSC_c12480 657a1da34d82d920e173eda2ff4c8cb0 374 Pfam PF09344 CT1975-like protein 4 332 5.3E-116 T 12-10-2018 IPR010148 CRISPR-associated protein, CT1975 TSC_c12480 657a1da34d82d920e173eda2ff4c8cb0 374 TIGRFAM TIGR01869 casC_Cse4: CRISPR-associated protein Cas7/Cse4/CasC, subtype I-E/ECOLI 4 328 1.5E-97 T 12-10-2018 IPR010148 CRISPR-associated protein, CT1975 TSC_c21310 bdce91c3bb57797bde8c6fc41c89b62e 326 Gene3D G3DSA:3.20.20.70 1 326 5.6E-140 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c21310 bdce91c3bb57797bde8c6fc41c89b62e 326 Pfam PF00490 Delta-aminolevulinic acid dehydratase 2 322 2.6E-136 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSC_c21310 bdce91c3bb57797bde8c6fc41c89b62e 326 SMART SM01004 1 323 1.2E-214 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSC_c21310 bdce91c3bb57797bde8c6fc41c89b62e 326 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 242 254 - T 12-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSC_c21310 bdce91c3bb57797bde8c6fc41c89b62e 326 PIRSF PIRSF001415 1 326 2.2E-141 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSC_c21310 bdce91c3bb57797bde8c6fc41c89b62e 326 SUPERFAMILY SSF51569 3 325 5.86E-130 T 12-10-2018 TSC_c21310 bdce91c3bb57797bde8c6fc41c89b62e 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 117 131 8.8E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSC_c21310 bdce91c3bb57797bde8c6fc41c89b62e 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 267 282 8.8E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSC_c21310 bdce91c3bb57797bde8c6fc41c89b62e 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 8.8E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSC_c21310 bdce91c3bb57797bde8c6fc41c89b62e 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 242 258 8.8E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSC_c21310 bdce91c3bb57797bde8c6fc41c89b62e 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 297 316 8.8E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSC_c21310 bdce91c3bb57797bde8c6fc41c89b62e 326 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 8.8E-58 T 12-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 TSC_c14830 68ce1f801ee889e0a43351224b5fb9ae 268 SUPERFAMILY SSF161098 2 268 5.49E-68 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c14830 68ce1f801ee889e0a43351224b5fb9ae 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 260 6.8E-23 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c14830 68ce1f801ee889e0a43351224b5fb9ae 268 Gene3D G3DSA:1.10.3720.10 1 255 1.1E-58 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c05510 e44185079719766dde3d059e4c8c16cc 235 Pfam PF01048 Phosphorylase superfamily 16 231 8.4E-44 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TSC_c05510 e44185079719766dde3d059e4c8c16cc 235 Gene3D G3DSA:3.40.50.1580 1 235 6.5E-79 T 12-10-2018 TSC_c05510 e44185079719766dde3d059e4c8c16cc 235 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 62 77 - T 12-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 TSC_c05510 e44185079719766dde3d059e4c8c16cc 235 SUPERFAMILY SSF53167 4 233 9.95E-77 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TSC_c14450 01a6027e221e486d1a75421da2f9f7e1 439 Gene3D G3DSA:3.90.1310.10 42 110 3.9E-8 T 12-10-2018 TSC_c14450 01a6027e221e486d1a75421da2f9f7e1 439 Gene3D G3DSA:3.40.710.10 171 348 1.6E-71 T 12-10-2018 TSC_c14450 01a6027e221e486d1a75421da2f9f7e1 439 SUPERFAMILY SSF56601 110 435 5.47E-65 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSC_c14450 01a6027e221e486d1a75421da2f9f7e1 439 Gene3D G3DSA:3.30.450.330 111 428 1.6E-71 T 12-10-2018 TSC_c14450 01a6027e221e486d1a75421da2f9f7e1 439 Pfam PF00905 Penicillin binding protein transpeptidase domain 135 422 3.5E-44 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TSC_c11500 2f844dfe7a8339d2e249f87f23d26fc9 317 Pfam PF02653 Branched-chain amino acid transport system / permease component 40 293 1.5E-32 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSC_c21370 6ea3189d4485e397e37edf38bb4eb890 88 Pfam PF11950 Protein of unknown function (DUF3467) 6 79 9.1E-19 T 12-10-2018 IPR021857 Protein of unknown function DUF3467 TSC_c16830 5e0a187a8377dfee2f06bf5eeebb4e34 251 Gene3D G3DSA:3.90.550.10 1 218 2.7E-31 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c16830 5e0a187a8377dfee2f06bf5eeebb4e34 251 SUPERFAMILY SSF53448 2 232 3.7E-37 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c16830 5e0a187a8377dfee2f06bf5eeebb4e34 251 Pfam PF00535 Glycosyl transferase family 2 3 112 5.4E-20 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSC_c24790 2b3c92e69421aa1413986f8cac417287 287 Pfam PF01145 SPFH domain / Band 7 family 63 229 1.6E-26 T 12-10-2018 IPR001107 Band 7 domain TSC_c24790 2b3c92e69421aa1413986f8cac417287 287 Gene3D G3DSA:3.30.479.30 90 222 2.0E-10 T 12-10-2018 TSC_c24790 2b3c92e69421aa1413986f8cac417287 287 SUPERFAMILY SSF117892 96 222 1.96E-12 T 12-10-2018 IPR036013 Band 7/SPFH domain superfamily TSC_c24790 2b3c92e69421aa1413986f8cac417287 287 SMART SM00244 59 220 2.5E-12 T 12-10-2018 IPR001107 Band 7 domain TSC_c02380 7e81df403ec3f8ae6c0525cdc43f8e2e 69 Gene3D G3DSA:3.30.160.250 3 62 1.0E-7 T 12-10-2018 TSC_c02380 7e81df403ec3f8ae6c0525cdc43f8e2e 69 SUPERFAMILY SSF143100 6 48 1.96E-7 T 12-10-2018 IPR035069 TTHA1013/TTHA0281-like TSC_c03590 b3623f616f1eada3516a57effe4058d5 328 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 328 128.12 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 TSC_c03590 b3623f616f1eada3516a57effe4058d5 328 Pfam PF02504 Fatty acid synthesis protein 3 315 7.5E-100 T 12-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 TSC_c03590 b3623f616f1eada3516a57effe4058d5 328 Gene3D G3DSA:3.40.718.10 1 327 5.8E-119 T 12-10-2018 TSC_c03590 b3623f616f1eada3516a57effe4058d5 328 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 3 324 2.0E-92 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 TSC_c03590 b3623f616f1eada3516a57effe4058d5 328 SUPERFAMILY SSF53659 3 326 5.35E-90 T 12-10-2018 TSC_c03590 b3623f616f1eada3516a57effe4058d5 328 PIRSF PIRSF002465 1 328 3.2E-111 T 12-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 TSC_c19480 8971a504a9793bf14fe21c19a9679835 130 Gene3D G3DSA:1.10.10.1100 66 127 1.1E-9 T 12-10-2018 TSC_c17970 1c955a99d8f9b6e94d35e9e57fe97495 374 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 26 231 1.3E-44 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 TSC_c17970 1c955a99d8f9b6e94d35e9e57fe97495 374 SUPERFAMILY SSF53822 32 234 2.8E-10 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TSC_c12500 46ca8ccff964a460e0c9dc899d1bcd13 484 TIGRFAM TIGR02547 casA_cse1: CRISPR type I-E/ECOLI-associated protein CasA/Cse1 5 477 2.6E-82 T 12-10-2018 IPR013381 CRISPR-associated protein Cse1 TSC_c12500 46ca8ccff964a460e0c9dc899d1bcd13 484 Gene3D G3DSA:1.10.132.100 354 484 2.0E-31 T 12-10-2018 TSC_c12500 46ca8ccff964a460e0c9dc899d1bcd13 484 Pfam PF09481 CRISPR-associated protein Cse1 (CRISPR_cse1) 5 444 7.4E-100 T 12-10-2018 IPR013381 CRISPR-associated protein Cse1 TSC_c00990 8cae9e4ace929207f2395686fa88172f 586 Gene3D G3DSA:1.20.210.10 13 549 1.2E-194 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00990 8cae9e4ace929207f2395686fa88172f 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 21 46 1.8E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00990 8cae9e4ace929207f2395686fa88172f 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 261 282 1.8E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00990 8cae9e4ace929207f2395686fa88172f 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 94 118 1.8E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00990 8cae9e4ace929207f2395686fa88172f 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 444 465 1.8E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00990 8cae9e4ace929207f2395686fa88172f 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 331 352 1.8E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00990 8cae9e4ace929207f2395686fa88172f 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 394 413 1.8E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00990 8cae9e4ace929207f2395686fa88172f 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 66 89 1.8E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00990 8cae9e4ace929207f2395686fa88172f 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 366 384 1.8E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00990 8cae9e4ace929207f2395686fa88172f 586 PRINTS PR01165 Cytochrome c oxidase subunit I signature 307 322 1.8E-73 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00990 8cae9e4ace929207f2395686fa88172f 586 SUPERFAMILY SSF81442 17 541 7.59E-159 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00990 8cae9e4ace929207f2395686fa88172f 586 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 31 491 1.9E-136 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00990 8cae9e4ace929207f2395686fa88172f 586 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 263 317 - T 12-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c13740 0bffa38381fd9a230dc0005a14f58a06 111 Pfam PF01609 Transposase DDE domain 2 93 7.6E-9 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TSC_c04230 7b898d3b09a4db7d2f066c69eec8e847 1119 SUPERFAMILY SSF64484 4 1113 0.0 T 12-10-2018 TSC_c04230 7b898d3b09a4db7d2f066c69eec8e847 1119 Gene3D G3DSA:2.40.50.150 707 834 0.0 T 12-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04230 7b898d3b09a4db7d2f066c69eec8e847 1119 Pfam PF00562 RNA polymerase Rpb2, domain 6 597 1026 7.9E-149 T 12-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04230 7b898d3b09a4db7d2f066c69eec8e847 1119 Gene3D G3DSA:3.90.1100.10 9 596 0.0 T 12-10-2018 TSC_c04230 7b898d3b09a4db7d2f066c69eec8e847 1119 ProSitePatterns PS01166 RNA polymerases beta chain signature. 836 848 - T 12-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04230 7b898d3b09a4db7d2f066c69eec8e847 1119 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 231 808 8.5E-255 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04230 7b898d3b09a4db7d2f066c69eec8e847 1119 Gene3D G3DSA:3.90.1110.10 147 328 0.0 T 12-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04230 7b898d3b09a4db7d2f066c69eec8e847 1119 Pfam PF04563 RNA polymerase beta subunit 18 379 2.2E-38 T 12-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04230 7b898d3b09a4db7d2f066c69eec8e847 1119 Pfam PF04561 RNA polymerase Rpb2, domain 2 142 334 3.4E-11 T 12-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04230 7b898d3b09a4db7d2f066c69eec8e847 1119 Gene3D G3DSA:2.30.150.10 474 539 0.0 T 12-10-2018 TSC_c04230 7b898d3b09a4db7d2f066c69eec8e847 1119 Gene3D G3DSA:2.40.270.10 7 1004 0.0 T 12-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04230 7b898d3b09a4db7d2f066c69eec8e847 1119 Gene3D G3DSA:3.90.1800.10 1014 1067 1.6E-10 T 12-10-2018 TSC_c04230 7b898d3b09a4db7d2f066c69eec8e847 1119 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 4 1104 11.772 T 12-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04230 7b898d3b09a4db7d2f066c69eec8e847 1119 Pfam PF10385 RNA polymerase beta subunit external 1 domain 471 535 2.6E-24 T 12-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04230 7b898d3b09a4db7d2f066c69eec8e847 1119 Pfam PF04560 RNA polymerase Rpb2, domain 7 1028 1102 5.2E-26 T 12-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c04230 7b898d3b09a4db7d2f066c69eec8e847 1119 Gene3D G3DSA:2.40.50.100 597 671 0.0 T 12-10-2018 TSC_c04230 7b898d3b09a4db7d2f066c69eec8e847 1119 Pfam PF04565 RNA polymerase Rpb2, domain 3 393 461 4.1E-29 T 12-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 TSC_c20660 26bbc04fdd9ad0e807ad0f80efa0ed54 377 SUPERFAMILY SSF53067 58 175 1.88E-17 T 12-10-2018 TSC_c20660 26bbc04fdd9ad0e807ad0f80efa0ed54 377 Pfam PF11104 Type IV pilus assembly protein PilM; 17 372 7.2E-52 T 12-10-2018 IPR005883 Type IV pilus assembly protein PilM TSC_c20660 26bbc04fdd9ad0e807ad0f80efa0ed54 377 Gene3D G3DSA:3.30.420.40 188 336 8.6E-108 T 12-10-2018 TSC_c20660 26bbc04fdd9ad0e807ad0f80efa0ed54 377 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 15 373 2.6E-88 T 12-10-2018 IPR005883 Type IV pilus assembly protein PilM TSC_c20660 26bbc04fdd9ad0e807ad0f80efa0ed54 377 Gene3D G3DSA:3.30.1490.300 89 149 8.6E-108 T 12-10-2018 TSC_c20660 26bbc04fdd9ad0e807ad0f80efa0ed54 377 Gene3D G3DSA:3.30.420.40 16 371 8.6E-108 T 12-10-2018 TSC_c20660 26bbc04fdd9ad0e807ad0f80efa0ed54 377 PIRSF PIRSF019169 2 374 5.3E-97 T 12-10-2018 IPR005883 Type IV pilus assembly protein PilM TSC_c20660 26bbc04fdd9ad0e807ad0f80efa0ed54 377 SUPERFAMILY SSF53067 190 372 1.94E-21 T 12-10-2018 TSC_c14690 e7c611d948036f73df790b36c9cde360 191 SMART SM00418 85 178 3.0E-17 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c14690 e7c611d948036f73df790b36c9cde360 191 SUPERFAMILY SSF46785 82 179 8.11E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c14690 e7c611d948036f73df790b36c9cde360 191 Gene3D G3DSA:1.10.10.10 79 190 1.1E-25 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c14690 e7c611d948036f73df790b36c9cde360 191 Pfam PF12840 Helix-turn-helix domain 86 158 5.4E-13 T 12-10-2018 TSC_c12880 c9433dc08e8bb12cf5f6b32f0dbed591 334 Pfam PF00005 ABC transporter 34 176 5.6E-35 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c12880 c9433dc08e8bb12cf5f6b32f0dbed591 334 Pfam PF08402 TOBE domain 263 329 3.9E-13 T 12-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 TSC_c12880 c9433dc08e8bb12cf5f6b32f0dbed591 334 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c12880 c9433dc08e8bb12cf5f6b32f0dbed591 334 Gene3D G3DSA:3.40.50.300 11 253 7.6E-75 T 12-10-2018 TSC_c12880 c9433dc08e8bb12cf5f6b32f0dbed591 334 SMART SM00382 43 226 6.7E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c12880 c9433dc08e8bb12cf5f6b32f0dbed591 334 SUPERFAMILY SSF50331 261 332 3.13E-10 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSC_c12880 c9433dc08e8bb12cf5f6b32f0dbed591 334 SUPERFAMILY SSF52540 19 256 3.69E-83 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c10200 327a76894df2b8ea5bc1927241e94e22 295 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 278 1.1E-38 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSC_c23930 cc7f3b544451704fff42362cf273c3de 302 Pfam PF00480 ROK family 4 292 2.7E-68 T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TSC_c23930 cc7f3b544451704fff42362cf273c3de 302 Gene3D G3DSA:3.30.420.40 4 290 1.4E-109 T 12-10-2018 TSC_c23930 cc7f3b544451704fff42362cf273c3de 302 Gene3D G3DSA:3.30.420.40 124 277 1.4E-109 T 12-10-2018 TSC_c23930 cc7f3b544451704fff42362cf273c3de 302 SUPERFAMILY SSF53067 1 296 2.41E-63 T 12-10-2018 TSC_c23930 cc7f3b544451704fff42362cf273c3de 302 ProSitePatterns PS01125 ROK family signature. 132 159 - T 12-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 TSC_c05310 80d54d30cdab653eb0b79ec907c29ea5 309 Pfam PF01636 Phosphotransferase enzyme family 56 263 2.9E-10 T 12-10-2018 IPR002575 Aminoglycoside phosphotransferase TSC_c05310 80d54d30cdab653eb0b79ec907c29ea5 309 SUPERFAMILY SSF56112 34 276 8.75E-22 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TSC_c05310 80d54d30cdab653eb0b79ec907c29ea5 309 Gene3D G3DSA:3.90.1200.10 111 299 8.0E-8 T 12-10-2018 TSC_c06810 486e4a6afe2c59dd9ab0bd6d9666e6fd 323 Gene3D G3DSA:3.90.180.10 18 309 5.8E-69 T 12-10-2018 TSC_c06810 486e4a6afe2c59dd9ab0bd6d9666e6fd 323 Pfam PF00107 Zinc-binding dehydrogenase 169 286 7.1E-16 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSC_c06810 486e4a6afe2c59dd9ab0bd6d9666e6fd 323 SUPERFAMILY SSF50129 2 168 3.3E-41 T 12-10-2018 IPR011032 GroES-like superfamily TSC_c06810 486e4a6afe2c59dd9ab0bd6d9666e6fd 323 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 129 3.5E-26 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSC_c06810 486e4a6afe2c59dd9ab0bd6d9666e6fd 323 SUPERFAMILY SSF51735 138 286 5.22E-26 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c06810 486e4a6afe2c59dd9ab0bd6d9666e6fd 323 Gene3D G3DSA:3.40.50.720 147 271 5.8E-69 T 12-10-2018 TSC_c13720 ca47604227e0a60ec9a5eab0a02a1cb3 96 Gene3D G3DSA:3.30.420.10 1 92 5.8E-5 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSC_c13720 ca47604227e0a60ec9a5eab0a02a1cb3 96 Pfam PF13683 Integrase core domain 12 77 9.5E-21 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 TSC_c13720 ca47604227e0a60ec9a5eab0a02a1cb3 96 SUPERFAMILY SSF53098 4 81 1.46E-15 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c02250 3e10c34d483e8486936d62b1d438b6f0 147 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 146 9.4E-42 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c02250 3e10c34d483e8486936d62b1d438b6f0 147 SUPERFAMILY SSF55658 1 56 1.6E-18 T 12-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal TSC_c02250 3e10c34d483e8486936d62b1d438b6f0 147 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 147 25.465 T 12-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c02250 3e10c34d483e8486936d62b1d438b6f0 147 Gene3D G3DSA:3.40.5.10 1 59 5.7E-27 T 12-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c02250 3e10c34d483e8486936d62b1d438b6f0 147 SUPERFAMILY SSF55653 57 145 1.23E-23 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily TSC_c02250 3e10c34d483e8486936d62b1d438b6f0 147 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c02250 3e10c34d483e8486936d62b1d438b6f0 147 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 2.4E-23 T 12-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c02250 3e10c34d483e8486936d62b1d438b6f0 147 Pfam PF03948 Ribosomal protein L9, C-terminal domain 63 146 7.1E-24 T 12-10-2018 IPR020069 Ribosomal protein L9, C-terminal TSC_c02250 3e10c34d483e8486936d62b1d438b6f0 147 Gene3D G3DSA:3.10.430.100 60 147 1.4E-30 T 12-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily TSC_c15550 3b33afad798d9ad56ae41f174486bb7a 293 SUPERFAMILY SSF51366 17 266 2.35E-67 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSC_c15550 3b33afad798d9ad56ae41f174486bb7a 293 PIRSF PIRSF029271 1 293 2.4E-156 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TSC_c15550 3b33afad798d9ad56ae41f174486bb7a 293 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 3 293 53.136 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TSC_c15550 3b33afad798d9ad56ae41f174486bb7a 293 Pfam PF01680 SOR/SNZ family 6 211 7.1E-110 T 12-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TSC_c15550 3b33afad798d9ad56ae41f174486bb7a 293 Gene3D G3DSA:3.20.20.70 1 293 7.0E-154 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c15550 3b33afad798d9ad56ae41f174486bb7a 293 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 8 293 3.6E-151 T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TSC_c15550 3b33afad798d9ad56ae41f174486bb7a 293 ProSitePatterns PS01235 PdxS/SNZ family signature. 204 222 - T 12-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 TSC_c11580 6120ba6ff88d758908fb3efc646dc3cb 64 Pfam PF01361 Tautomerase enzyme 4 58 2.0E-12 T 12-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 TSC_c11580 6120ba6ff88d758908fb3efc646dc3cb 64 SUPERFAMILY SSF55331 1 61 4.71E-15 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily TSC_c11580 6120ba6ff88d758908fb3efc646dc3cb 64 Gene3D G3DSA:3.30.429.10 1 64 3.8E-21 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily TSC_c22780 65e8a22c9172280b3190811a20ecadf6 136 Gene3D G3DSA:3.40.50.620 1 136 2.0E-47 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c22780 65e8a22c9172280b3190811a20ecadf6 136 SUPERFAMILY SSF52402 3 135 2.8E-32 T 12-10-2018 TSC_c11470 010b7c4425688f7b5434303c60fb3c59 170 Gene3D G3DSA:3.10.450.50 1 170 2.2E-61 T 12-10-2018 TSC_c11470 010b7c4425688f7b5434303c60fb3c59 170 Pfam PF00866 Ring hydroxylating beta subunit 14 162 1.2E-42 T 12-10-2018 IPR000391 Ring-hydroxylating dioxygenase beta subunit GO:0006725|GO:0055114 TSC_c11470 010b7c4425688f7b5434303c60fb3c59 170 SUPERFAMILY SSF54427 2 170 1.17E-50 T 12-10-2018 IPR032710 NTF2-like domain superfamily TSC_c10430 f8ecdcd8877e856d2a51c16eae8e7498 246 SUPERFAMILY SSF56529 37 244 5.1E-72 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSC_c10430 f8ecdcd8877e856d2a51c16eae8e7498 246 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 45 242 3.7E-61 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 TSC_c10430 f8ecdcd8877e856d2a51c16eae8e7498 246 Gene3D G3DSA:2.30.30.370 1 40 1.8E-23 T 12-10-2018 TSC_c10430 f8ecdcd8877e856d2a51c16eae8e7498 246 TIGRFAM TIGR02303 HpaG-C-term: 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit 2 245 8.7E-118 T 12-10-2018 IPR012684 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit GO:0008704|GO:0018800|GO:1901023 KEGG: 00350+5.3.3.10+4.1.1.68 TSC_c10430 f8ecdcd8877e856d2a51c16eae8e7498 246 Gene3D G3DSA:3.90.850.10 41 246 1.2E-74 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSC_c01150 a41e37360266384e7e0cd2f9d7333e9a 465 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 23 122 1.3E-10 T 12-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TSC_c01150 a41e37360266384e7e0cd2f9d7333e9a 465 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 154 455 1.3E-119 T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TSC_c01150 a41e37360266384e7e0cd2f9d7333e9a 465 Gene3D G3DSA:3.40.630.10 150 461 1.7E-123 T 12-10-2018 TSC_c01150 a41e37360266384e7e0cd2f9d7333e9a 465 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 464 33.5 T 12-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 TSC_c01150 a41e37360266384e7e0cd2f9d7333e9a 465 Gene3D G3DSA:3.40.220.10 1 149 2.5E-17 T 12-10-2018 TSC_c01150 a41e37360266384e7e0cd2f9d7333e9a 465 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 313 320 - T 12-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 TSC_c01150 a41e37360266384e7e0cd2f9d7333e9a 465 PRINTS PR00481 Cytosol aminopeptidase signature 337 352 3.5E-49 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TSC_c01150 a41e37360266384e7e0cd2f9d7333e9a 465 PRINTS PR00481 Cytosol aminopeptidase signature 250 271 3.5E-49 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TSC_c01150 a41e37360266384e7e0cd2f9d7333e9a 465 PRINTS PR00481 Cytosol aminopeptidase signature 309 329 3.5E-49 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TSC_c01150 a41e37360266384e7e0cd2f9d7333e9a 465 PRINTS PR00481 Cytosol aminopeptidase signature 287 308 3.5E-49 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TSC_c01150 a41e37360266384e7e0cd2f9d7333e9a 465 PRINTS PR00481 Cytosol aminopeptidase signature 228 245 3.5E-49 T 12-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 TSC_c01150 a41e37360266384e7e0cd2f9d7333e9a 465 SUPERFAMILY SSF52949 20 152 5.18E-15 T 12-10-2018 TSC_c01150 a41e37360266384e7e0cd2f9d7333e9a 465 SUPERFAMILY SSF53187 149 459 6.59E-109 T 12-10-2018 TSC_c07620 df633fc5dd5d6cd1afee647ff72f059c 345 SMART SM01329 2 340 1.2E-186 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TSC_c07620 df633fc5dd5d6cd1afee647ff72f059c 345 Gene3D G3DSA:3.40.718.10 1 345 2.1E-155 T 12-10-2018 TSC_c07620 df633fc5dd5d6cd1afee647ff72f059c 345 SUPERFAMILY SSF53659 1 344 6.84E-121 T 12-10-2018 TSC_c07620 df633fc5dd5d6cd1afee647ff72f059c 345 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 2 343 2.1E-158 T 12-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 TSC_c07620 df633fc5dd5d6cd1afee647ff72f059c 345 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 237 256 - T 12-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 TSC_c07620 df633fc5dd5d6cd1afee647ff72f059c 345 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 340 2.2E-129 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TSC_c07620 df633fc5dd5d6cd1afee647ff72f059c 345 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 1 344 47.196 T 12-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 TSC_c03340 9f87dea31a67f27f75457a1d717119a8 212 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3 206 1.3E-60 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TSC_c03340 9f87dea31a67f27f75457a1d717119a8 212 Gene3D G3DSA:3.90.550.10 1 212 9.0E-68 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c03340 9f87dea31a67f27f75457a1d717119a8 212 SUPERFAMILY SSF53448 1 206 1.98E-45 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c03340 9f87dea31a67f27f75457a1d717119a8 212 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2 206 3.6E-50 T 12-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TSC_c03340 9f87dea31a67f27f75457a1d717119a8 212 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 85 92 - T 12-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TSC_c03340 9f87dea31a67f27f75457a1d717119a8 212 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 1 207 39.257 T 12-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 TSC_c17680 c4ffed467472a2a39be97d1d96f8c49b 98 Gene3D G3DSA:2.60.120.10 1 95 1.4E-12 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TSC_c17680 c4ffed467472a2a39be97d1d96f8c49b 98 SUPERFAMILY SSF51182 11 96 4.83E-9 T 12-10-2018 IPR011051 RmlC-like cupin domain superfamily TSC_c17680 c4ffed467472a2a39be97d1d96f8c49b 98 Pfam PF02311 AraC-like ligand binding domain 48 86 9.0E-5 T 12-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 TSC_c09250 dda31b86bf6124536ffbcd945980db99 139 SUPERFAMILY SSF52242 2 131 1.7E-50 T 12-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 TSC_c09250 dda31b86bf6124536ffbcd945980db99 139 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 3 131 3.5E-52 T 12-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 TSC_c09250 dda31b86bf6124536ffbcd945980db99 139 Pfam PF02310 B12 binding domain 5 120 1.2E-24 T 12-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 TSC_c09250 dda31b86bf6124536ffbcd945980db99 139 Gene3D G3DSA:3.40.50.280 1 137 2.5E-61 T 12-10-2018 TSC_c01210 034824c15c64f80cfd176f386e313ec7 418 Gene3D G3DSA:2.40.50.100 1 79 1.0E-23 T 12-10-2018 TSC_c01210 034824c15c64f80cfd176f386e313ec7 418 Gene3D G3DSA:4.10.320.10 109 160 2.2E-16 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TSC_c01210 034824c15c64f80cfd176f386e313ec7 418 Pfam PF02817 e3 binding domain 120 155 3.5E-14 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 TSC_c01210 034824c15c64f80cfd176f386e313ec7 418 SUPERFAMILY SSF52777 177 414 6.23E-86 T 12-10-2018 TSC_c01210 034824c15c64f80cfd176f386e313ec7 418 SUPERFAMILY SSF51230 2 92 2.05E-24 T 12-10-2018 IPR011053 Single hybrid motif TSC_c01210 034824c15c64f80cfd176f386e313ec7 418 Gene3D G3DSA:3.30.559.10 171 417 5.4E-93 T 12-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 TSC_c01210 034824c15c64f80cfd176f386e313ec7 418 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 187 415 2.0E-86 T 12-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 TSC_c01210 034824c15c64f80cfd176f386e313ec7 418 Pfam PF00364 Biotin-requiring enzyme 2 73 2.8E-20 T 12-10-2018 IPR000089 Biotin/lipoyl attachment TSC_c01210 034824c15c64f80cfd176f386e313ec7 418 SUPERFAMILY SSF47005 115 159 4.45E-12 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TSC_c01210 034824c15c64f80cfd176f386e313ec7 418 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 25 54 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TSC_c03220 5c981581f136ecb4681597a1ad4666d2 285 Pfam PF01039 Carboxyl transferase domain 95 236 6.9E-14 T 12-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 TSC_c03220 5c981581f136ecb4681597a1ad4666d2 285 SUPERFAMILY SSF52096 22 277 1.3E-79 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSC_c03220 5c981581f136ecb4681597a1ad4666d2 285 Gene3D G3DSA:3.90.226.10 22 278 4.1E-84 T 12-10-2018 TSC_c03220 5c981581f136ecb4681597a1ad4666d2 285 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 15 274 6.6E-110 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c03220 5c981581f136ecb4681597a1ad4666d2 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 159 177 1.8E-37 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c03220 5c981581f136ecb4681597a1ad4666d2 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 225 236 1.8E-37 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c03220 5c981581f136ecb4681597a1ad4666d2 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 196 213 1.8E-37 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c03220 5c981581f136ecb4681597a1ad4666d2 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 247 256 1.8E-37 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c03220 5c981581f136ecb4681597a1ad4666d2 285 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 125 139 1.8E-37 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c03220 5c981581f136ecb4681597a1ad4666d2 285 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 4 277 38.375 T 12-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 TSC_c05240 77c5ba5e61ba0f73a0b196d16f743bb6 704 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 173 612 8.0E-54 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSC_c05240 77c5ba5e61ba0f73a0b196d16f743bb6 704 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 130 689 1.8E-114 T 12-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ TSC_c24390 b60b2005fb0c01fca831774ebff0f9cf 132 SUPERFAMILY SSF88723 2 126 1.6E-14 T 12-10-2018 IPR029060 PIN-like domain superfamily TSC_c24390 b60b2005fb0c01fca831774ebff0f9cf 132 Gene3D G3DSA:3.40.50.1010 3 127 3.0E-21 T 12-10-2018 TSC_c24390 b60b2005fb0c01fca831774ebff0f9cf 132 Pfam PF01850 PIN domain 4 118 1.5E-12 T 12-10-2018 IPR002716 PIN domain TSC_c08580 be6756a28d176fbaebdde1b877464d5b 412 PIRSF PIRSF000099 2 412 1.0E-148 T 12-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSC_c08580 be6756a28d176fbaebdde1b877464d5b 412 Gene3D G3DSA:3.40.50.1980 219 334 4.1E-112 T 12-10-2018 TSC_c08580 be6756a28d176fbaebdde1b877464d5b 412 SUPERFAMILY SSF53720 24 411 4.32E-73 T 12-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 TSC_c08580 be6756a28d176fbaebdde1b877464d5b 412 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 2 412 39.177 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSC_c08580 be6756a28d176fbaebdde1b877464d5b 412 Pfam PF00815 Histidinol dehydrogenase 21 411 1.1E-146 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSC_c08580 be6756a28d176fbaebdde1b877464d5b 412 PRINTS PR00083 Histidinol dehydrogenase signature 156 182 4.2E-77 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSC_c08580 be6756a28d176fbaebdde1b877464d5b 412 PRINTS PR00083 Histidinol dehydrogenase signature 186 211 4.2E-77 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSC_c08580 be6756a28d176fbaebdde1b877464d5b 412 PRINTS PR00083 Histidinol dehydrogenase signature 346 364 4.2E-77 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSC_c08580 be6756a28d176fbaebdde1b877464d5b 412 PRINTS PR00083 Histidinol dehydrogenase signature 237 256 4.2E-77 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSC_c08580 be6756a28d176fbaebdde1b877464d5b 412 PRINTS PR00083 Histidinol dehydrogenase signature 215 236 4.2E-77 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSC_c08580 be6756a28d176fbaebdde1b877464d5b 412 PRINTS PR00083 Histidinol dehydrogenase signature 305 330 4.2E-77 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSC_c08580 be6756a28d176fbaebdde1b877464d5b 412 PRINTS PR00083 Histidinol dehydrogenase signature 27 51 4.2E-77 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSC_c08580 be6756a28d176fbaebdde1b877464d5b 412 PRINTS PR00083 Histidinol dehydrogenase signature 125 151 4.2E-77 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSC_c08580 be6756a28d176fbaebdde1b877464d5b 412 Gene3D G3DSA:3.40.50.1980 24 218 4.1E-112 T 12-10-2018 TSC_c08580 be6756a28d176fbaebdde1b877464d5b 412 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 27 411 4.4E-143 T 12-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 TSC_c01810 ec67fa4849de3ce416b917bb10feb7cf 125 Gene3D G3DSA:3.30.1390.10 56 125 2.9E-27 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TSC_c01810 ec67fa4849de3ce416b917bb10feb7cf 125 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 60 125 7.9E-26 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c01810 ec67fa4849de3ce416b917bb10feb7cf 125 SUPERFAMILY SSF54736 55 125 1.5E-22 T 12-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like TSC_c01810 ec67fa4849de3ce416b917bb10feb7cf 125 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 51 4.0E-17 T 12-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c01810 ec67fa4849de3ce416b917bb10feb7cf 125 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 61 125 2.0E-14 T 12-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c01810 ec67fa4849de3ce416b917bb10feb7cf 125 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 125 5.4E-41 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c01810 ec67fa4849de3ce416b917bb10feb7cf 125 Gene3D G3DSA:1.20.5.710 3 55 2.7E-17 T 12-10-2018 TSC_c01810 ec67fa4849de3ce416b917bb10feb7cf 125 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 125 23.267 T 12-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c01810 ec67fa4849de3ce416b917bb10feb7cf 125 SUPERFAMILY SSF48300 4 62 3.79E-14 T 12-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c23510 e23b259cbb3498ae24d65fd752d3ab23 262 Pfam PF04468 PSP1 C-terminal conserved region 60 141 1.1E-13 T 12-10-2018 IPR007557 PSP1, C-terminal TSC_c00730 badd5b34c6303a093b1f932fb7f7ff61 153 Pfam PF01966 HD domain 49 140 2.0E-4 T 12-10-2018 IPR006674 HD domain TSC_c00730 badd5b34c6303a093b1f932fb7f7ff61 153 SUPERFAMILY SSF109604 43 151 1.26E-8 T 12-10-2018 TSC_c00460 8abd5ff94374150a2454132bd877a068 269 Pfam PF12849 PBP superfamily domain 17 194 8.5E-16 T 12-10-2018 IPR024370 PBP domain TSC_c00460 8abd5ff94374150a2454132bd877a068 269 SUPERFAMILY SSF53850 21 245 1.14E-22 T 12-10-2018 TSC_c00460 8abd5ff94374150a2454132bd877a068 269 Gene3D G3DSA:3.40.190.10 23 244 1.2E-73 T 12-10-2018 TSC_c00460 8abd5ff94374150a2454132bd877a068 269 Gene3D G3DSA:3.40.190.10 98 211 1.2E-73 T 12-10-2018 TSC_c21980 70b13f2a26a56f5d62dbdacae7b44ba3 208 Pfam PF13545 Crp-like helix-turn-helix domain 140 204 6.3E-17 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSC_c21980 70b13f2a26a56f5d62dbdacae7b44ba3 208 SUPERFAMILY SSF46785 137 206 2.27E-14 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c21980 70b13f2a26a56f5d62dbdacae7b44ba3 208 Pfam PF00027 Cyclic nucleotide-binding domain 20 101 1.8E-14 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain TSC_c21980 70b13f2a26a56f5d62dbdacae7b44ba3 208 SUPERFAMILY SSF51206 1 133 2.09E-23 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like TSC_c21980 70b13f2a26a56f5d62dbdacae7b44ba3 208 Gene3D G3DSA:2.60.120.10 1 138 1.3E-24 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TSC_c21980 70b13f2a26a56f5d62dbdacae7b44ba3 208 SMART SM00100 1 120 2.5E-12 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain TSC_c21980 70b13f2a26a56f5d62dbdacae7b44ba3 208 Gene3D G3DSA:1.10.10.10 139 208 9.2E-17 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c21980 70b13f2a26a56f5d62dbdacae7b44ba3 208 SMART SM00419 151 197 3.4E-6 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSC_c05120 7a5a1dbc7b7f9353acafcd08d39124ff 146 Gene3D G3DSA:2.40.33.20 1 146 3.8E-27 T 12-10-2018 TSC_c05120 7a5a1dbc7b7f9353acafcd08d39124ff 146 SUPERFAMILY SSF50800 2 143 4.29E-26 T 12-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily TSC_c05120 7a5a1dbc7b7f9353acafcd08d39124ff 146 Pfam PF03473 MOSC domain 42 141 3.2E-7 T 12-10-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 TSC_c12050 af9515679c8ec6737fa7dd7c7ddca673 367 SUPERFAMILY SSF161098 54 355 6.46E-50 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c12050 af9515679c8ec6737fa7dd7c7ddca673 367 Gene3D G3DSA:1.10.3720.10 171 360 6.0E-31 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c12050 af9515679c8ec6737fa7dd7c7ddca673 367 Gene3D G3DSA:1.10.3720.10 6 166 2.8E-23 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c12050 af9515679c8ec6737fa7dd7c7ddca673 367 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 359 5.1E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c01950 b58d50c2f241575c15a06a706e405a5d 527 Pfam PF09210 Domain of unknown function (DUF1957) 428 515 1.4E-21 T 12-10-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TSC_c01950 b58d50c2f241575c15a06a706e405a5d 527 Gene3D G3DSA:1.20.1430.10 414 519 1.7E-34 T 12-10-2018 IPR037090 Glycoside hydrolase families 57, central domain KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 TSC_c01950 b58d50c2f241575c15a06a706e405a5d 527 Gene3D G3DSA:3.20.110.10 1 413 1.2E-169 T 12-10-2018 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily TSC_c01950 b58d50c2f241575c15a06a706e405a5d 527 SUPERFAMILY SSF88713 2 413 2.8E-124 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSC_c01950 b58d50c2f241575c15a06a706e405a5d 527 Pfam PF03065 Glycosyl hydrolase family 57 6 364 4.6E-45 T 12-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 TSC_c01950 b58d50c2f241575c15a06a706e405a5d 527 SUPERFAMILY SSF88688 413 515 9.16E-31 T 12-10-2018 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily TSC_c10330 2cf2772123a1aa66119e1b9a9b5afa92 521 SUPERFAMILY SSF52283 23 121 1.38E-32 T 12-10-2018 TSC_c10330 2cf2772123a1aa66119e1b9a9b5afa92 521 Pfam PF01842 ACT domain 448 511 8.2E-14 T 12-10-2018 IPR002912 ACT domain TSC_c10330 2cf2772123a1aa66119e1b9a9b5afa92 521 SUPERFAMILY SSF143548 314 443 1.91E-23 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 TSC_c10330 2cf2772123a1aa66119e1b9a9b5afa92 521 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 217 233 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TSC_c10330 2cf2772123a1aa66119e1b9a9b5afa92 521 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 139 166 - T 12-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 TSC_c10330 2cf2772123a1aa66119e1b9a9b5afa92 521 Gene3D G3DSA:3.40.50.720 22 302 1.2E-111 T 12-10-2018 TSC_c10330 2cf2772123a1aa66119e1b9a9b5afa92 521 SUPERFAMILY SSF55021 439 516 7.91E-18 T 12-10-2018 TSC_c10330 2cf2772123a1aa66119e1b9a9b5afa92 521 Gene3D G3DSA:3.30.70.260 448 521 8.0E-23 T 12-10-2018 TSC_c10330 2cf2772123a1aa66119e1b9a9b5afa92 521 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 103 278 9.7E-61 T 12-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 TSC_c10330 2cf2772123a1aa66119e1b9a9b5afa92 521 Gene3D G3DSA:3.40.50.720 94 276 1.2E-111 T 12-10-2018 TSC_c10330 2cf2772123a1aa66119e1b9a9b5afa92 521 Gene3D G3DSA:3.30.1330.90 314 447 2.3E-26 T 12-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 TSC_c10330 2cf2772123a1aa66119e1b9a9b5afa92 521 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 188 210 - T 12-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site TSC_c10330 2cf2772123a1aa66119e1b9a9b5afa92 521 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 21 303 1.2E-31 T 12-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 TSC_c10330 2cf2772123a1aa66119e1b9a9b5afa92 521 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 3 520 4.7E-181 T 12-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 TSC_c10330 2cf2772123a1aa66119e1b9a9b5afa92 521 SUPERFAMILY SSF51735 97 279 9.69E-59 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c10830 f5b74382430443cc45d69c77d846fd51 503 Gene3D G3DSA:3.20.20.300 6 328 9.2E-99 T 12-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 TSC_c10830 f5b74382430443cc45d69c77d846fd51 503 PRINTS PR00133 Glycosyl hydrolase family 3 signature 243 261 3.9E-5 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TSC_c10830 f5b74382430443cc45d69c77d846fd51 503 PRINTS PR00133 Glycosyl hydrolase family 3 signature 89 108 3.9E-5 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TSC_c10830 f5b74382430443cc45d69c77d846fd51 503 SUPERFAMILY SSF51445 28 327 1.47E-74 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TSC_c10830 f5b74382430443cc45d69c77d846fd51 503 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 58 301 1.2E-71 T 12-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 TSC_c10830 f5b74382430443cc45d69c77d846fd51 503 Gene3D G3DSA:3.40.50.1700 336 498 3.4E-7 T 12-10-2018 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily GO:0004553|GO:0005975 TSC_c18340 d53f636f530181f440eb36399b12e510 347 PIRSF PIRSF000164 14 343 1.3E-95 T 12-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 TSC_c18340 d53f636f530181f440eb36399b12e510 347 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 1 341 8.4E-117 T 12-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TSC_c18340 d53f636f530181f440eb36399b12e510 347 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 327 46.23 T 12-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 TSC_c18340 d53f636f530181f440eb36399b12e510 347 SUPERFAMILY SSF51395 3 342 9.47E-97 T 12-10-2018 TSC_c18340 d53f636f530181f440eb36399b12e510 347 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 80 99 - T 12-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 TSC_c18340 d53f636f530181f440eb36399b12e510 347 Pfam PF01180 Dihydroorotate dehydrogenase 45 331 3.0E-82 T 12-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 TSC_c18340 d53f636f530181f440eb36399b12e510 347 Gene3D G3DSA:3.20.20.70 1 344 4.6E-119 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c09980 84623baea716600d0c3097a140022bb9 127 SUPERFAMILY SSF81593 2 126 2.9E-42 T 12-10-2018 TSC_c09980 84623baea716600d0c3097a140022bb9 127 SMART SM00748 8 119 4.7E-29 T 12-10-2018 IPR007842 HEPN domain TSC_c09980 84623baea716600d0c3097a140022bb9 127 Gene3D G3DSA:1.20.120.330 1 127 5.4E-39 T 12-10-2018 TSC_c09980 84623baea716600d0c3097a140022bb9 127 Pfam PF05168 HEPN domain 4 125 3.9E-34 T 12-10-2018 IPR007842 HEPN domain TSC_c17430 9b31c47ce56d9208461a0fc472c32efe 145 Gene3D G3DSA:1.20.210.10 34 140 1.2E-5 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c17430 9b31c47ce56d9208461a0fc472c32efe 145 SUPERFAMILY SSF81442 16 130 8.11E-5 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c05660 b8d1295d52d8de039e975fbb44df8994 461 Pfam PF11283 Protein of unknown function (DUF3084) 4 78 1.4E-24 T 12-10-2018 IPR021435 Protein of unknown function DUF3084 TSC_c20640 d29b9022c301289a3724040ae083201e 172 Pfam PF17248 Family of unknown function (DUF5317) 2 136 3.9E-34 T 12-10-2018 IPR035168 Protein of unknown function DUF5317 TSC_c19220 7fedc924df0503d1052b7bedf952408f 429 Pfam PF13347 MFS/sugar transport protein 7 417 1.1E-70 T 12-10-2018 TSC_c19220 7fedc924df0503d1052b7bedf952408f 429 SUPERFAMILY SSF103473 6 412 1.57E-39 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c19220 7fedc924df0503d1052b7bedf952408f 429 Gene3D G3DSA:1.20.1250.20 210 416 1.3E-12 T 12-10-2018 TSC_c19220 7fedc924df0503d1052b7bedf952408f 429 Gene3D G3DSA:1.20.1250.20 2 202 6.2E-18 T 12-10-2018 TSC_c01290 c8447cb799a05ce91288fc35f8e3f9c6 399 PRINTS PR00758 Arsenical pump membrane protein signature 109 133 2.7E-8 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TSC_c01290 c8447cb799a05ce91288fc35f8e3f9c6 399 PRINTS PR00758 Arsenical pump membrane protein signature 273 297 2.7E-8 T 12-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 TSC_c01290 c8447cb799a05ce91288fc35f8e3f9c6 399 Pfam PF03600 Citrate transporter 33 337 1.0E-31 T 12-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 TSC_c21570 fe65a4cc39fb18797c1cda4e0c382b37 128 SUPERFAMILY SSF102712 4 119 1.96E-21 T 12-10-2018 TSC_c21570 fe65a4cc39fb18797c1cda4e0c382b37 128 Pfam PF14464 Prokaryotic homologs of the JAB domain 9 108 4.8E-21 T 12-10-2018 IPR028090 JAB domain, prokaryotic TSC_c21570 fe65a4cc39fb18797c1cda4e0c382b37 128 Gene3D G3DSA:3.40.140.10 4 127 1.1E-26 T 12-10-2018 TSC_c14200 9e61bdd5a686a93ec1bd6a65a9c91c83 262 Gene3D G3DSA:3.40.50.12280 126 258 2.5E-45 T 12-10-2018 TSC_c14200 9e61bdd5a686a93ec1bd6a65a9c91c83 262 SUPERFAMILY SSF56770 127 255 4.71E-45 T 12-10-2018 TSC_c14200 9e61bdd5a686a93ec1bd6a65a9c91c83 262 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 156 246 1.1E-19 T 12-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c14200 9e61bdd5a686a93ec1bd6a65a9c91c83 262 SUPERFAMILY SSF54862 38 85 3.94E-8 T 12-10-2018 TSC_c14200 9e61bdd5a686a93ec1bd6a65a9c91c83 262 Gene3D G3DSA:3.30.70.20 46 82 2.0E-5 T 12-10-2018 TSC_c07950 cef05c7d7f19f75a21abc8eaef61b35c 88 Pfam PF00571 CBS domain 34 85 8.0E-15 T 12-10-2018 IPR000644 CBS domain TSC_c07950 cef05c7d7f19f75a21abc8eaef61b35c 88 SUPERFAMILY SSF54631 6 84 5.63E-21 T 12-10-2018 TSC_c07950 cef05c7d7f19f75a21abc8eaef61b35c 88 Gene3D G3DSA:3.10.580.10 1 87 2.4E-26 T 12-10-2018 TSC_c07950 cef05c7d7f19f75a21abc8eaef61b35c 88 SMART SM00116 41 87 4.1E-12 T 12-10-2018 IPR000644 CBS domain TSC_c13400 8282b2c2cddfe0b24bb67cbae2ca6314 161 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 64 8.4E-18 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSC_c13400 8282b2c2cddfe0b24bb67cbae2ca6314 161 Gene3D G3DSA:3.40.50.620 1 160 2.7E-58 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c13400 8282b2c2cddfe0b24bb67cbae2ca6314 161 Pfam PF01467 Cytidylyltransferase-like 4 134 2.5E-21 T 12-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 TSC_c13400 8282b2c2cddfe0b24bb67cbae2ca6314 161 SUPERFAMILY SSF52374 2 157 2.41E-46 T 12-10-2018 TSC_c13400 8282b2c2cddfe0b24bb67cbae2ca6314 161 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 158 2.9E-60 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TSC_c13400 8282b2c2cddfe0b24bb67cbae2ca6314 161 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 1 159 36.747 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TSC_c13400 8282b2c2cddfe0b24bb67cbae2ca6314 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 6.0E-40 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TSC_c13400 8282b2c2cddfe0b24bb67cbae2ca6314 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 6.0E-40 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TSC_c13400 8282b2c2cddfe0b24bb67cbae2ca6314 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 1 19 6.0E-40 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TSC_c13400 8282b2c2cddfe0b24bb67cbae2ca6314 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 19 40 6.0E-40 T 12-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 TSC_c24160 c751f4651875e7b48ba5f69546017553 292 SUPERFAMILY SSF52540 4 210 1.24E-56 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c24160 c751f4651875e7b48ba5f69546017553 292 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c24160 c751f4651875e7b48ba5f69546017553 292 Gene3D G3DSA:3.40.50.300 1 227 3.3E-59 T 12-10-2018 TSC_c24160 c751f4651875e7b48ba5f69546017553 292 Pfam PF00005 ABC transporter 19 160 8.0E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c24160 c751f4651875e7b48ba5f69546017553 292 SMART SM00382 28 229 1.7E-12 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c18760 681b09890f4e3da10631a49574fa4c84 586 Pfam PF02867 Ribonucleotide reductase, barrel domain 98 562 1.5E-113 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSC_c18760 681b09890f4e3da10631a49574fa4c84 586 SUPERFAMILY SSF51998 95 566 1.13E-120 T 12-10-2018 TSC_c18760 681b09890f4e3da10631a49574fa4c84 586 Gene3D G3DSA:3.20.70.20 18 573 1.4E-163 T 12-10-2018 TSC_c18760 681b09890f4e3da10631a49574fa4c84 586 PRINTS PR01183 Ribonucleotide reductase large chain signature 318 341 5.7E-35 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSC_c18760 681b09890f4e3da10631a49574fa4c84 586 PRINTS PR01183 Ribonucleotide reductase large chain signature 280 291 5.7E-35 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSC_c18760 681b09890f4e3da10631a49574fa4c84 586 PRINTS PR01183 Ribonucleotide reductase large chain signature 440 467 5.7E-35 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSC_c18760 681b09890f4e3da10631a49574fa4c84 586 PRINTS PR01183 Ribonucleotide reductase large chain signature 172 191 5.7E-35 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSC_c18760 681b09890f4e3da10631a49574fa4c84 586 PRINTS PR01183 Ribonucleotide reductase large chain signature 358 380 5.7E-35 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSC_c18760 681b09890f4e3da10631a49574fa4c84 586 PRINTS PR01183 Ribonucleotide reductase large chain signature 386 409 5.7E-35 T 12-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 TSC_c18760 681b09890f4e3da10631a49574fa4c84 586 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 27 497 1.2E-131 T 12-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 TSC_c00170 bc11878055ec8af53d63cf07ec5b66be 499 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 12 483 1.2E-105 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSC_c11780 109d5ad5c64b8e52228d6f5ebaee5498 254 SUPERFAMILY SSF69618 2 251 2.22E-42 T 12-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSC_c11780 109d5ad5c64b8e52228d6f5ebaee5498 254 Gene3D G3DSA:3.40.50.10090 9 242 1.8E-68 T 12-10-2018 TSC_c11780 109d5ad5c64b8e52228d6f5ebaee5498 254 Pfam PF02602 Uroporphyrinogen-III synthase HemD 15 244 2.6E-32 T 12-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSC_c11780 109d5ad5c64b8e52228d6f5ebaee5498 254 Gene3D G3DSA:3.40.50.10090 33 161 1.8E-68 T 12-10-2018 TSC_c23130 7883b408965a65583475484c2526a64b 251 Pfam PF02591 C4-type zinc ribbon domain 215 246 4.3E-9 T 12-10-2018 IPR003743 C4-type zinc ribbon domain TSC_c23130 7883b408965a65583475484c2526a64b 251 SUPERFAMILY SSF90257 29 148 2.33E-5 T 12-10-2018 TSC_c04520 117caf3f6063bb6cdb24e57f673e603d 228 Pfam PF00881 Nitroreductase family 91 227 3.1E-13 T 12-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 TSC_c04520 117caf3f6063bb6cdb24e57f673e603d 228 Gene3D G3DSA:3.40.109.10 9 228 2.3E-41 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSC_c04520 117caf3f6063bb6cdb24e57f673e603d 228 SUPERFAMILY SSF55469 92 227 1.86E-14 T 12-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 TSC_c11180 4457ee89da9bd2b68672f3c81d5123ee 405 Gene3D G3DSA:2.30.42.10 283 404 6.4E-21 T 12-10-2018 TSC_c11180 4457ee89da9bd2b68672f3c81d5123ee 405 Gene3D G3DSA:2.40.10.120 53 272 1.3E-64 T 12-10-2018 TSC_c11180 4457ee89da9bd2b68672f3c81d5123ee 405 Pfam PF13365 Trypsin-like peptidase domain 100 236 1.3E-31 T 12-10-2018 TSC_c11180 4457ee89da9bd2b68672f3c81d5123ee 405 PRINTS PR00834 HtrA/DegQ protease family signature 131 151 8.5E-40 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c11180 4457ee89da9bd2b68672f3c81d5123ee 405 PRINTS PR00834 HtrA/DegQ protease family signature 171 195 8.5E-40 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c11180 4457ee89da9bd2b68672f3c81d5123ee 405 PRINTS PR00834 HtrA/DegQ protease family signature 207 224 8.5E-40 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c11180 4457ee89da9bd2b68672f3c81d5123ee 405 PRINTS PR00834 HtrA/DegQ protease family signature 229 246 8.5E-40 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c11180 4457ee89da9bd2b68672f3c81d5123ee 405 PRINTS PR00834 HtrA/DegQ protease family signature 109 121 8.5E-40 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c11180 4457ee89da9bd2b68672f3c81d5123ee 405 SUPERFAMILY SSF50156 230 403 8.84E-14 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 TSC_c11180 4457ee89da9bd2b68672f3c81d5123ee 405 SMART SM00228 287 392 0.0011 T 12-10-2018 IPR001478 PDZ domain GO:0005515 TSC_c11180 4457ee89da9bd2b68672f3c81d5123ee 405 SUPERFAMILY SSF50494 54 275 1.62E-56 T 12-10-2018 IPR009003 Peptidase S1, PA clan TSC_c11180 4457ee89da9bd2b68672f3c81d5123ee 405 Pfam PF13180 PDZ domain 287 399 3.2E-12 T 12-10-2018 IPR001478 PDZ domain GO:0005515 TSC_c21640 d845dfcff95d68d343a57d1e731c272a 123 Pfam PF09862 Protein of unknown function (DUF2089) 10 119 2.1E-41 T 12-10-2018 IPR018658 Protein of unknown function DUF2089 TSC_c12520 e594baa8bdb510afc29a72a923f945ca 322 Pfam PF08279 HTH domain 13 54 2.5E-6 T 12-10-2018 IPR013196 Helix-turn-helix, type 11 TSC_c12520 e594baa8bdb510afc29a72a923f945ca 322 Pfam PF13280 WYL domain 128 310 1.1E-37 T 12-10-2018 IPR026881 WYL domain TSC_c12520 e594baa8bdb510afc29a72a923f945ca 322 SUPERFAMILY SSF46785 8 61 1.36E-6 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c12520 e594baa8bdb510afc29a72a923f945ca 322 PIRSF PIRSF016838 62 318 7.7E-14 T 12-10-2018 IPR028349 Protein PafC TSC_c12520 e594baa8bdb510afc29a72a923f945ca 322 PIRSF PIRSF016838 1 51 0.091 T 12-10-2018 IPR028349 Protein PafC TSC_c12520 e594baa8bdb510afc29a72a923f945ca 322 Gene3D G3DSA:1.10.10.10 2 62 1.6E-7 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c22510 1fdc97830ef4c67faf1acbd9697a9a3c 373 Pfam PF12704 MacB-like periplasmic core domain 19 210 3.9E-9 T 12-10-2018 IPR025857 MacB-like periplasmic core domain TSC_c22510 1fdc97830ef4c67faf1acbd9697a9a3c 373 Pfam PF02687 FtsX-like permease family 271 368 1.3E-10 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TSC_c06890 20745bad3ca1a45c670538f3cc2c139f 128 SUPERFAMILY SSF51230 3 126 9.42E-50 T 12-10-2018 IPR011053 Single hybrid motif TSC_c06890 20745bad3ca1a45c670538f3cc2c139f 128 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 127 6.2E-50 T 12-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 TSC_c06890 20745bad3ca1a45c670538f3cc2c139f 128 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 41.254 T 12-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 TSC_c06890 20745bad3ca1a45c670538f3cc2c139f 128 Gene3D G3DSA:2.40.50.100 1 128 7.2E-58 T 12-10-2018 TSC_c06890 20745bad3ca1a45c670538f3cc2c139f 128 Pfam PF01597 Glycine cleavage H-protein 8 126 2.1E-47 T 12-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate TSC_c06890 20745bad3ca1a45c670538f3cc2c139f 128 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 12-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 TSC_c06570 6290ba4194623256dae214470a812599 431 Gene3D G3DSA:3.65.10.10 15 419 1.7E-140 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TSC_c06570 6290ba4194623256dae214470a812599 431 Gene3D G3DSA:3.65.10.10 30 236 1.7E-140 T 12-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 TSC_c06570 6290ba4194623256dae214470a812599 431 SUPERFAMILY SSF55205 13 421 2.29E-109 T 12-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 TSC_c06570 6290ba4194623256dae214470a812599 431 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 10 422 36.46 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSC_c06570 6290ba4194623256dae214470a812599 431 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 12 419 4.4E-142 T 12-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 TSC_c06570 6290ba4194623256dae214470a812599 431 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 16 412 1.1E-70 T 12-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 TSC_c13850 c7f0fdaf0574868499cca8dc4cc940e8 153 Gene3D G3DSA:2.30.30.790 8 118 9.7E-22 T 12-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c13850 c7f0fdaf0574868499cca8dc4cc940e8 153 PRINTS PR00061 Ribosomal protein L19 signature 6 35 1.6E-37 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c13850 c7f0fdaf0574868499cca8dc4cc940e8 153 PRINTS PR00061 Ribosomal protein L19 signature 66 89 1.6E-37 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c13850 c7f0fdaf0574868499cca8dc4cc940e8 153 PRINTS PR00061 Ribosomal protein L19 signature 36 65 1.6E-37 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c13850 c7f0fdaf0574868499cca8dc4cc940e8 153 Pfam PF01245 Ribosomal protein L19 6 113 1.6E-43 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c13850 c7f0fdaf0574868499cca8dc4cc940e8 153 SUPERFAMILY SSF50104 4 117 1.6E-42 T 12-10-2018 IPR008991 Translation protein SH3-like domain superfamily TSC_c13850 c7f0fdaf0574868499cca8dc4cc940e8 153 PIRSF PIRSF002191 1 139 2.2E-47 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c13850 c7f0fdaf0574868499cca8dc4cc940e8 153 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 6 112 1.1E-39 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c13850 c7f0fdaf0574868499cca8dc4cc940e8 153 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 4 116 26.424 T 12-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c13850 c7f0fdaf0574868499cca8dc4cc940e8 153 ProSitePatterns PS01015 Ribosomal protein L19 signature. 88 103 - T 12-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c12970 28f15a0416e2735610d5600549a4a0f5 200 Pfam PF13187 4Fe-4S dicluster domain 133 192 2.6E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c12970 28f15a0416e2735610d5600549a4a0f5 200 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 25 42 - T 12-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c12970 28f15a0416e2735610d5600549a4a0f5 200 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 1 68 1.4E-11 T 12-10-2018 TSC_c12970 28f15a0416e2735610d5600549a4a0f5 200 Gene3D G3DSA:3.30.70.20 114 195 6.7E-20 T 12-10-2018 TSC_c12970 28f15a0416e2735610d5600549a4a0f5 200 Gene3D G3DSA:3.10.20.740 1 93 1.4E-21 T 12-10-2018 TSC_c12970 28f15a0416e2735610d5600549a4a0f5 200 SUPERFAMILY SSF54862 68 195 5.51E-19 T 12-10-2018 TSC_c12970 28f15a0416e2735610d5600549a4a0f5 200 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 178 189 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c12970 28f15a0416e2735610d5600549a4a0f5 200 SUPERFAMILY SSF54292 1 89 6.42E-22 T 12-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 TSC_c12080 1995a8b04c471e073dea7c6524b8ba3c 348 Pfam PF04041 beta-1,4-mannooligosaccharide phosphorylase 28 342 9.0E-41 T 12-10-2018 IPR007184 Mannoside phosphorylase TSC_c12080 1995a8b04c471e073dea7c6524b8ba3c 348 Gene3D G3DSA:2.115.10.20 29 347 3.3E-32 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TSC_c12080 1995a8b04c471e073dea7c6524b8ba3c 348 SUPERFAMILY SSF75005 52 337 1.71E-28 T 12-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily TSC_c22900 beb3a0b935addd9e636efc180191c203 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 391 425 1.9E-9 T 12-10-2018 IPR001451 Hexapeptide repeat TSC_c22900 beb3a0b935addd9e636efc180191c203 453 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 265 294 3.8E-4 T 12-10-2018 IPR001451 Hexapeptide repeat TSC_c22900 beb3a0b935addd9e636efc180191c203 453 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 399 427 - T 12-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 TSC_c22900 beb3a0b935addd9e636efc180191c203 453 Pfam PF12804 MobA-like NTP transferase domain 5 128 4.8E-22 T 12-10-2018 IPR025877 MobA-like NTP transferase TSC_c22900 beb3a0b935addd9e636efc180191c203 453 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 1 448 39.809 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 TSC_c22900 beb3a0b935addd9e636efc180191c203 453 SUPERFAMILY SSF53448 5 248 3.76E-59 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c22900 beb3a0b935addd9e636efc180191c203 453 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 4 450 2.8E-169 T 12-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 TSC_c22900 beb3a0b935addd9e636efc180191c203 453 Gene3D G3DSA:2.160.10.10 249 436 6.5E-56 T 12-10-2018 TSC_c22900 beb3a0b935addd9e636efc180191c203 453 Gene3D G3DSA:3.90.550.10 3 247 4.3E-71 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c22900 beb3a0b935addd9e636efc180191c203 453 SUPERFAMILY SSF51161 251 434 1.04E-48 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily TSC_c18130 32d4fa6a2bd5625cd2b152af57839ad3 244 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 235 1.8E-80 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c18130 32d4fa6a2bd5625cd2b152af57839ad3 244 Gene3D G3DSA:3.30.70.980 136 201 1.3E-50 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c18130 32d4fa6a2bd5625cd2b152af57839ad3 244 SUPERFAMILY SSF75625 3 237 2.62E-78 T 12-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c18130 32d4fa6a2bd5625cd2b152af57839ad3 244 Gene3D G3DSA:3.30.70.980 87 234 1.3E-50 T 12-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c18130 32d4fa6a2bd5625cd2b152af57839ad3 244 Pfam PF01709 Transcriptional regulator 5 235 1.9E-81 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c18130 32d4fa6a2bd5625cd2b152af57839ad3 244 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 237 31.54 T 12-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c18130 32d4fa6a2bd5625cd2b152af57839ad3 244 Gene3D G3DSA:1.10.10.200 1 82 4.1E-27 T 12-10-2018 IPR017856 Integrase-like, N-terminal TSC_c19180 6b3c2ea5860e9a66d257455e07963860 512 SUPERFAMILY SSF54373 247 335 1.96E-8 T 12-10-2018 TSC_c19180 6b3c2ea5860e9a66d257455e07963860 512 Gene3D G3DSA:3.50.50.60 17 374 2.8E-112 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c19180 6b3c2ea5860e9a66d257455e07963860 512 Gene3D G3DSA:3.30.9.10 101 336 2.8E-112 T 12-10-2018 TSC_c19180 6b3c2ea5860e9a66d257455e07963860 512 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 406 495 8.2E-26 T 12-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSC_c19180 6b3c2ea5860e9a66d257455e07963860 512 Pfam PF01266 FAD dependent oxidoreductase 17 362 4.5E-51 T 12-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 TSC_c19180 6b3c2ea5860e9a66d257455e07963860 512 SUPERFAMILY SSF51905 13 263 3.42E-32 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c19180 6b3c2ea5860e9a66d257455e07963860 512 Gene3D G3DSA:1.10.8.870 404 511 6.5E-30 T 12-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSC_c19180 6b3c2ea5860e9a66d257455e07963860 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 97 109 3.9E-26 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSC_c19180 6b3c2ea5860e9a66d257455e07963860 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 29 39 3.9E-26 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSC_c19180 6b3c2ea5860e9a66d257455e07963860 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 329 335 3.9E-26 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSC_c19180 6b3c2ea5860e9a66d257455e07963860 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 16 28 3.9E-26 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSC_c19180 6b3c2ea5860e9a66d257455e07963860 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 356 368 3.9E-26 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSC_c19180 6b3c2ea5860e9a66d257455e07963860 512 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 45 57 3.9E-26 T 12-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 TSC_c18190 43af00f69cf4a15587b984f31cc7b2af 141 Gene3D G3DSA:3.40.630.30 1 141 2.8E-70 T 12-10-2018 TSC_c18190 43af00f69cf4a15587b984f31cc7b2af 141 SUPERFAMILY SSF55729 1 130 1.68E-50 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSC_c18190 43af00f69cf4a15587b984f31cc7b2af 141 Pfam PF09390 Protein of unknown function (DUF1999) 23 139 4.4E-36 T 12-10-2018 IPR018987 Protein of unknown function DUF1999 TSC_c16740 12c5fe984634cbc2466d2d70ab28d5e5 318 Pfam PF03109 ABC1 family 131 243 7.6E-25 T 12-10-2018 IPR004147 UbiB domain TSC_c16740 12c5fe984634cbc2466d2d70ab28d5e5 318 SUPERFAMILY SSF56112 107 298 2.21E-14 T 12-10-2018 IPR011009 Protein kinase-like domain superfamily TSC_c24750 0b39eb610428fa7ee6fe6ac6a7bb123d 187 Gene3D G3DSA:1.20.1200.10 12 187 1.7E-64 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TSC_c24750 0b39eb610428fa7ee6fe6ac6a7bb123d 187 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 181 1.2E-65 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TSC_c24750 0b39eb610428fa7ee6fe6ac6a7bb123d 187 SUPERFAMILY SSF89028 1 182 2.16E-66 T 12-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TSC_c24750 0b39eb610428fa7ee6fe6ac6a7bb123d 187 Pfam PF01923 Cobalamin adenosyltransferase 3 170 3.1E-64 T 12-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TSC_c24750 0b39eb610428fa7ee6fe6ac6a7bb123d 187 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 181 2.0E-75 T 12-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 TSC_c01260 372f4aea4cfbd3cec4be63dbb784d94c 164 Gene3D G3DSA:3.40.980.10 1 162 3.1E-58 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSC_c01260 372f4aea4cfbd3cec4be63dbb784d94c 164 Pfam PF00994 Probable molybdopterin binding domain 5 148 5.8E-35 T 12-10-2018 IPR001453 MoaB/Mog domain TSC_c01260 372f4aea4cfbd3cec4be63dbb784d94c 164 SMART SM00852 5 149 3.3E-33 T 12-10-2018 IPR001453 MoaB/Mog domain TSC_c01260 372f4aea4cfbd3cec4be63dbb784d94c 164 SUPERFAMILY SSF53218 2 153 5.23E-47 T 12-10-2018 IPR036425 MoaB/Mog-like domain superfamily TSC_c01260 372f4aea4cfbd3cec4be63dbb784d94c 164 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 65 78 - T 12-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 TSC_c01260 372f4aea4cfbd3cec4be63dbb784d94c 164 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 3 143 1.5E-35 T 12-10-2018 IPR001453 MoaB/Mog domain TSC_c24500 09a76ebd1eb256e76446e374b841e754 149 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 2 149 13.472 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSC_c24500 09a76ebd1eb256e76446e374b841e754 149 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 86 101 8.8E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSC_c24500 09a76ebd1eb256e76446e374b841e754 149 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 43 51 8.8E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSC_c24500 09a76ebd1eb256e76446e374b841e754 149 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 125 141 8.8E-16 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSC_c24500 09a76ebd1eb256e76446e374b841e754 149 Pfam PF01252 Signal peptidase (SPase) II 7 141 4.2E-30 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSC_c24500 09a76ebd1eb256e76446e374b841e754 149 TIGRFAM TIGR00077 lspA: signal peptidase II 8 142 3.7E-32 T 12-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 TSC_c02740 9fa1f30c2545cd53323c262ca0cd6d54 400 Gene3D G3DSA:1.20.5.470 370 400 3.7E-18 T 12-10-2018 TSC_c02740 9fa1f30c2545cd53323c262ca0cd6d54 400 SUPERFAMILY SSF69864 169 394 6.54E-97 T 12-10-2018 TSC_c02740 9fa1f30c2545cd53323c262ca0cd6d54 400 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 6 14 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSC_c02740 9fa1f30c2545cd53323c262ca0cd6d54 400 Hamap MF_00005 Argininosuccinate synthase [argG]. 1 395 54.25 T 12-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSC_c02740 9fa1f30c2545cd53323c262ca0cd6d54 400 Gene3D G3DSA:3.90.1260.10 61 351 3.1E-167 T 12-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSC_c02740 9fa1f30c2545cd53323c262ca0cd6d54 400 Pfam PF00764 Arginosuccinate synthase 4 389 6.4E-165 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSC_c02740 9fa1f30c2545cd53323c262ca0cd6d54 400 TIGRFAM TIGR00032 argG: argininosuccinate synthase 2 389 6.3E-157 T 12-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSC_c02740 9fa1f30c2545cd53323c262ca0cd6d54 400 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 114 125 - T 12-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 TSC_c02740 9fa1f30c2545cd53323c262ca0cd6d54 400 Gene3D G3DSA:3.40.50.620 3 170 3.1E-167 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c02740 9fa1f30c2545cd53323c262ca0cd6d54 400 SUPERFAMILY SSF52402 1 203 4.19E-52 T 12-10-2018 TSC_c03350 6f9ed7e38a446ece381826764f66b74c 272 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 1 266 29.722 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 TSC_c03350 6f9ed7e38a446ece381826764f66b74c 272 Gene3D G3DSA:3.30.70.890 149 264 3.9E-29 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TSC_c03350 6f9ed7e38a446ece381826764f66b74c 272 SUPERFAMILY SSF55060 150 257 3.6E-21 T 12-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily TSC_c03350 6f9ed7e38a446ece381826764f66b74c 272 Pfam PF00288 GHMP kinases N terminal domain 78 133 5.8E-6 T 12-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 TSC_c03350 6f9ed7e38a446ece381826764f66b74c 272 Gene3D G3DSA:3.30.230.10 1 148 1.4E-47 T 12-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup TSC_c03350 6f9ed7e38a446ece381826764f66b74c 272 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 5 249 3.1E-47 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 TSC_c03350 6f9ed7e38a446ece381826764f66b74c 272 Pfam PF08544 GHMP kinases C terminal 203 259 3.4E-9 T 12-10-2018 IPR013750 GHMP kinase, C-terminal domain TSC_c03350 6f9ed7e38a446ece381826764f66b74c 272 SUPERFAMILY SSF54211 4 146 3.72E-35 T 12-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold TSC_c03350 6f9ed7e38a446ece381826764f66b74c 272 PIRSF PIRSF010376 1 264 1.3E-71 T 12-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 TSC_c11390 050be95b18ce7de88a39738f52fe1927 334 TIGRFAM TIGR03211 catechol_2_3: catechol 2,3 dioxygenase 19 321 3.1E-100 T 12-10-2018 IPR017624 Catechol 2,3 dioxygenase GO:0008198|GO:0018577|GO:0019439|GO:0055114 KEGG: 00361+1.13.11.2|KEGG: 00362+1.13.11.2|KEGG: 00622+1.13.11.2|KEGG: 00643+1.13.11.2|MetaCyc: PWY-5419|MetaCyc: PWY-5641 TSC_c11390 050be95b18ce7de88a39738f52fe1927 334 SUPERFAMILY SSF54593 19 283 6.15E-41 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c11390 050be95b18ce7de88a39738f52fe1927 334 Gene3D G3DSA:3.10.180.10 162 330 2.6E-42 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c11390 050be95b18ce7de88a39738f52fe1927 334 Gene3D G3DSA:3.10.180.10 18 153 8.6E-37 T 12-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase TSC_c11390 050be95b18ce7de88a39738f52fe1927 334 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 22 130 2.8E-8 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TSC_c11390 050be95b18ce7de88a39738f52fe1927 334 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 163 281 1.4E-12 T 12-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain TSC_c07320 e3e34292c1943c4ddd2fcb7e3f67691d 296 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 12 194 31.7 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 TSC_c07320 e3e34292c1943c4ddd2fcb7e3f67691d 296 Gene3D G3DSA:3.40.50.170 5 205 1.1E-70 T 12-10-2018 TSC_c07320 e3e34292c1943c4ddd2fcb7e3f67691d 296 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 11 194 3.3E-60 T 12-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 TSC_c07320 e3e34292c1943c4ddd2fcb7e3f67691d 296 SUPERFAMILY SSF53328 12 200 2.88E-57 T 12-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TSC_c07320 e3e34292c1943c4ddd2fcb7e3f67691d 296 Pfam PF00551 Formyl transferase 12 188 2.7E-50 T 12-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 TSC_c12470 464b77974a0312691cc1319913445c12 224 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 3 45 4.1E-16 T 12-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal TSC_c12470 464b77974a0312691cc1319913445c12 224 Gene3D G3DSA:3.30.70.2660 1 219 1.2E-81 T 12-10-2018 TSC_c12470 464b77974a0312691cc1319913445c12 224 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 3 201 3.2E-53 T 12-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 TSC_c12470 464b77974a0312691cc1319913445c12 224 TIGRFAM TIGR01868 casD_Cas5e: CRISPR-associated protein Cas5/CasD, subtype I-E/ECOLI 3 167 2.7E-46 T 12-10-2018 IPR010147 CRISPR-associated protein, CasD GO:0003723|GO:0051607 TSC_c22800 2911f1e8a3a2c21d79fed4b4779d4452 347 Pfam PF03739 Predicted permease YjgP/YjgQ family 6 343 1.5E-68 T 12-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 TSC_c09490 eb44b89f28e33d2ac6a552d6ca66127e 136 SUPERFAMILY SSF82649 3 133 3.92E-23 T 12-10-2018 TSC_c09490 eb44b89f28e33d2ac6a552d6ca66127e 136 Gene3D G3DSA:3.90.1010.10 2 136 4.4E-46 T 12-10-2018 TSC_c09490 eb44b89f28e33d2ac6a552d6ca66127e 136 Pfam PF02657 Fe-S metabolism associated domain 17 128 3.5E-22 T 12-10-2018 IPR003808 Fe-S metabolism associated domain, SufE-like TSC_c16970 e59d37ce1df21ea23bb5b9350072154d 234 SUPERFAMILY SSF53633 1 233 8.12E-74 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSC_c16970 e59d37ce1df21ea23bb5b9350072154d 234 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 3 233 6.2E-92 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 TSC_c16970 e59d37ce1df21ea23bb5b9350072154d 234 Gene3D G3DSA:3.40.1160.10 1 234 5.5E-80 T 12-10-2018 IPR036393 Acetylglutamate kinase-like superfamily TSC_c16970 e59d37ce1df21ea23bb5b9350072154d 234 Pfam PF00696 Amino acid kinase family 4 212 4.2E-29 T 12-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 TSC_c16970 e59d37ce1df21ea23bb5b9350072154d 234 Hamap MF_01220_B Uridylate kinase [pyrH]. 1 233 44.483 T 12-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 TSC_c16970 e59d37ce1df21ea23bb5b9350072154d 234 PIRSF PIRSF005650 1 234 5.8E-93 T 12-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 TSC_c02920 3a56d5563edb373304f365b51b28dd7a 373 SUPERFAMILY SSF51971 1 371 8.83E-51 T 12-10-2018 TSC_c02920 3a56d5563edb373304f365b51b28dd7a 373 Gene3D G3DSA:3.40.50.720 1 90 1.5E-33 T 12-10-2018 TSC_c02920 3a56d5563edb373304f365b51b28dd7a 373 Gene3D G3DSA:3.40.50.720 280 373 1.5E-17 T 12-10-2018 TSC_c02920 3a56d5563edb373304f365b51b28dd7a 373 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 3 370 9.3E-132 T 12-10-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 TSC_c02920 3a56d5563edb373304f365b51b28dd7a 373 Pfam PF03275 UDP-galactopyranose mutase 153 353 2.8E-74 T 12-10-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 TSC_c02920 3a56d5563edb373304f365b51b28dd7a 373 Pfam PF13450 NAD(P)-binding Rossmann-like domain 7 74 8.5E-15 T 12-10-2018 TSC_c02920 3a56d5563edb373304f365b51b28dd7a 373 Gene3D G3DSA:3.40.50.720 156 275 1.5E-26 T 12-10-2018 TSC_c02920 3a56d5563edb373304f365b51b28dd7a 373 SUPERFAMILY SSF54373 251 320 4.12E-20 T 12-10-2018 TSC_c16710 3e0192685d1968b361cc11cc8847daf3 346 Gene3D G3DSA:3.40.50.720 157 291 8.6E-127 T 12-10-2018 TSC_c16710 3e0192685d1968b361cc11cc8847daf3 346 SMART SM00829 10 343 5.9E-6 T 12-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 TSC_c16710 3e0192685d1968b361cc11cc8847daf3 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 130 7.4E-31 T 12-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 TSC_c16710 3e0192685d1968b361cc11cc8847daf3 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 12-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 TSC_c16710 3e0192685d1968b361cc11cc8847daf3 346 Gene3D G3DSA:3.90.180.10 14 334 8.6E-127 T 12-10-2018 TSC_c16710 3e0192685d1968b361cc11cc8847daf3 346 Pfam PF00107 Zinc-binding dehydrogenase 179 305 6.5E-21 T 12-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 TSC_c16710 3e0192685d1968b361cc11cc8847daf3 346 SUPERFAMILY SSF51735 142 312 1.08E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c16710 3e0192685d1968b361cc11cc8847daf3 346 SUPERFAMILY SSF50129 1 179 3.04E-56 T 12-10-2018 IPR011032 GroES-like superfamily TSC_c17200 ebb224575cb7816a86eecf02a3c2225a 253 Pfam PF01925 Sulfite exporter TauE/SafE 5 243 1.5E-49 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TSC_c02670 2dadfd6f95daa2cd5033aff36a6971b1 528 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 363 418 1.9E-6 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TSC_c02670 2dadfd6f95daa2cd5033aff36a6971b1 528 Pfam PF07282 Putative transposase DNA-binding domain 393 460 1.7E-21 T 12-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal TSC_c23810 f0836d31c10bf01125910722418b9bb6 478 SUPERFAMILY SSF48452 22 440 1.61E-5 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c23810 f0836d31c10bf01125910722418b9bb6 478 Pfam PF04434 SWIM zinc finger 66 86 6.9E-5 T 12-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 TSC_c22570 31c833dda5d1d135d14b7f60ff22605e 312 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 3 241 8.2E-56 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c22570 31c833dda5d1d135d14b7f60ff22605e 312 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 308 14.827 T 12-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c22570 31c833dda5d1d135d14b7f60ff22605e 312 SUPERFAMILY SSF55120 3 243 3.68E-63 T 12-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 TSC_c22570 31c833dda5d1d135d14b7f60ff22605e 312 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 22 155 2.5E-40 T 12-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 TSC_c16190 89606567bd7f3ee181d17fe2998e1372 380 SUPERFAMILY SSF53300 260 354 2.22E-9 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSC_c16190 89606567bd7f3ee181d17fe2998e1372 380 Pfam PF13203 Putative metallopeptidase domain 3 244 4.7E-32 T 12-10-2018 IPR025154 Putative metallopeptidase domain TSC_c16190 89606567bd7f3ee181d17fe2998e1372 380 Pfam PF09967 VWA-like domain (DUF2201) 260 377 2.2E-19 T 12-10-2018 IPR018698 VWA-like domain TSC_c18580 7c4a8717037d2dd375f2a82034ff6954 574 Pfam PF08439 Oligopeptidase F 106 171 1.7E-18 T 12-10-2018 IPR013647 Oligopeptidase F, N-terminal domain TSC_c18580 7c4a8717037d2dd375f2a82034ff6954 574 Gene3D G3DSA:1.20.140.70 19 163 3.4E-14 T 12-10-2018 TSC_c18580 7c4a8717037d2dd375f2a82034ff6954 574 TIGRFAM TIGR02290 M3_fam_3: oligoendopeptidase, pepF/M3 family 5 573 2.1E-194 T 12-10-2018 IPR011977 Peptidase M3B, oligoendopeptidase-related clade 3 TSC_c18580 7c4a8717037d2dd375f2a82034ff6954 574 SUPERFAMILY SSF55486 4 561 8.2E-94 T 12-10-2018 TSC_c18580 7c4a8717037d2dd375f2a82034ff6954 574 Gene3D G3DSA:1.10.1370.20 211 574 2.8E-107 T 12-10-2018 TSC_c18580 7c4a8717037d2dd375f2a82034ff6954 574 Pfam PF01432 Peptidase family M3 186 562 2.4E-36 T 12-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 TSC_c23840 733596c7a761408c41c0c1eb88e4c9a3 185 SUPERFAMILY SSF52980 2 183 2.95E-19 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSC_c23840 733596c7a761408c41c0c1eb88e4c9a3 185 Pfam PF05685 Putative restriction endonuclease 10 180 4.4E-32 T 12-10-2018 IPR008538 Domain of unknown function DUF820 TSC_c23840 733596c7a761408c41c0c1eb88e4c9a3 185 Gene3D G3DSA:3.90.1570.10 2 185 3.1E-13 T 12-10-2018 TSC_c19080 eb90f1ddbe2e038a5ea9a567c7b97363 387 Pfam PF00266 Aminotransferase class-V 17 373 2.3E-70 T 12-10-2018 IPR000192 Aminotransferase class V domain TSC_c19080 eb90f1ddbe2e038a5ea9a567c7b97363 387 Gene3D G3DSA:3.90.1150.10 17 381 3.6E-133 T 12-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 TSC_c19080 eb90f1ddbe2e038a5ea9a567c7b97363 387 PIRSF PIRSF005572 14 387 1.9E-116 T 12-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 TSC_c19080 eb90f1ddbe2e038a5ea9a567c7b97363 387 SUPERFAMILY SSF53383 17 385 1.99E-101 T 12-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase TSC_c19080 eb90f1ddbe2e038a5ea9a567c7b97363 387 Gene3D G3DSA:3.40.640.10 28 265 3.6E-133 T 12-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 TSC_c05740 615e29a86ec629e8ac4d210859067692 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 281 1.6E-34 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSC_c10550 c0c0487ceb67e94033d0de4aedc2e6dd 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.1E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c10550 c0c0487ceb67e94033d0de4aedc2e6dd 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.1E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c10550 c0c0487ceb67e94033d0de4aedc2e6dd 265 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.1E-7 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c10550 c0c0487ceb67e94033d0de4aedc2e6dd 265 Pfam PF00106 short chain dehydrogenase 6 195 2.2E-50 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c10550 c0c0487ceb67e94033d0de4aedc2e6dd 265 SUPERFAMILY SSF51735 1 262 5.94E-66 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c10550 c0c0487ceb67e94033d0de4aedc2e6dd 265 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 191 3.8E-4 T 12-10-2018 TSC_c10550 c0c0487ceb67e94033d0de4aedc2e6dd 265 Gene3D G3DSA:3.40.50.720 1 263 1.2E-66 T 12-10-2018 TSC_c10550 c0c0487ceb67e94033d0de4aedc2e6dd 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.4E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c10550 c0c0487ceb67e94033d0de4aedc2e6dd 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 4.4E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c10550 c0c0487ceb67e94033d0de4aedc2e6dd 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 4.4E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c10550 c0c0487ceb67e94033d0de4aedc2e6dd 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.4E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c10550 c0c0487ceb67e94033d0de4aedc2e6dd 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 4.4E-22 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c00540 3d4739eb300ef6a8ea056f576602735e 265 Pfam PF02535 ZIP Zinc transporter 114 260 1.9E-16 T 12-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 TSC_c05420 da5a3a1404a863d8f2f21c5e98415ada 348 SUPERFAMILY SSF55103 134 257 2.62E-5 T 12-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 TSC_c05420 da5a3a1404a863d8f2f21c5e98415ada 348 Pfam PF01565 FAD binding domain 4 133 2.9E-25 T 12-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 TSC_c05420 da5a3a1404a863d8f2f21c5e98415ada 348 Gene3D G3DSA:3.30.465.40 3 189 2.7E-32 T 12-10-2018 TSC_c05420 da5a3a1404a863d8f2f21c5e98415ada 348 SUPERFAMILY SSF56176 4 170 2.8E-33 T 12-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 TSC_c06220 4bc49bffb6fb614a5619700d5d760289 367 SUPERFAMILY SSF52440 2 94 5.75E-22 T 12-10-2018 IPR016185 Pre-ATP-grasp domain superfamily TSC_c06220 4bc49bffb6fb614a5619700d5d760289 367 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 3 350 7.6E-116 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 TSC_c06220 4bc49bffb6fb614a5619700d5d760289 367 Gene3D G3DSA:3.40.50.20 3 96 2.2E-33 T 12-10-2018 TSC_c06220 4bc49bffb6fb614a5619700d5d760289 367 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 2 347 42.418 T 12-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 TSC_c06220 4bc49bffb6fb614a5619700d5d760289 367 SUPERFAMILY SSF56059 97 295 1.11E-65 T 12-10-2018 TSC_c06220 4bc49bffb6fb614a5619700d5d760289 367 SUPERFAMILY SSF51246 300 360 3.3E-17 T 12-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 TSC_c06220 4bc49bffb6fb614a5619700d5d760289 367 Gene3D G3DSA:3.30.470.20 176 364 1.6E-75 T 12-10-2018 TSC_c06220 4bc49bffb6fb614a5619700d5d760289 367 Pfam PF02222 ATP-grasp domain 106 275 4.2E-56 T 12-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type TSC_c06220 4bc49bffb6fb614a5619700d5d760289 367 Gene3D G3DSA:3.30.1490.20 97 175 6.1E-25 T 12-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 TSC_c03050 b9d9310c95807c213bd729cb71752a80 85 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 4 46 9.5E-11 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TSC_c03050 b9d9310c95807c213bd729cb71752a80 85 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 2 42 1.1E-11 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TSC_c03050 b9d9310c95807c213bd729cb71752a80 85 SMART SM00966 3 48 9.2E-12 T 12-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 TSC_c03050 b9d9310c95807c213bd729cb71752a80 85 Gene3D G3DSA:2.10.260.10 2 40 1.2E-11 T 12-10-2018 TSC_c03050 b9d9310c95807c213bd729cb71752a80 85 SUPERFAMILY SSF89447 3 45 6.67E-12 T 12-10-2018 IPR037914 SpoVT-AbrB domain superfamily TSC_c14350 b08660530cdde21cdf33d9679e9dcf49 471 ProSitePatterns PS00571 Amidases signature. 139 170 - T 12-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 TSC_c14350 b08660530cdde21cdf33d9679e9dcf49 471 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 6 459 87.777 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSC_c14350 b08660530cdde21cdf33d9679e9dcf49 471 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 7 459 1.2E-161 T 12-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSC_c14350 b08660530cdde21cdf33d9679e9dcf49 471 Pfam PF01425 Amidase 19 448 1.3E-140 T 12-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSC_c14350 b08660530cdde21cdf33d9679e9dcf49 471 Gene3D G3DSA:3.90.1300.10 1 471 3.8E-204 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSC_c14350 b08660530cdde21cdf33d9679e9dcf49 471 SUPERFAMILY SSF75304 3 458 6.67E-156 T 12-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 TSC_c03950 f589aa908bb7c66d47f975e7ea449a8c 443 Gene3D G3DSA:3.50.50.60 115 439 8.5E-160 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c03950 f589aa908bb7c66d47f975e7ea449a8c 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.2E-20 T 12-10-2018 TSC_c03950 f589aa908bb7c66d47f975e7ea449a8c 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 2.2E-20 T 12-10-2018 TSC_c03950 f589aa908bb7c66d47f975e7ea449a8c 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 276 283 2.2E-20 T 12-10-2018 TSC_c03950 f589aa908bb7c66d47f975e7ea449a8c 443 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 151 176 2.2E-20 T 12-10-2018 TSC_c03950 f589aa908bb7c66d47f975e7ea449a8c 443 Gene3D G3DSA:3.50.50.60 4 339 8.5E-160 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c03950 f589aa908bb7c66d47f975e7ea449a8c 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 4.6E-29 T 12-10-2018 TSC_c03950 f589aa908bb7c66d47f975e7ea449a8c 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 261 283 4.6E-29 T 12-10-2018 TSC_c03950 f589aa908bb7c66d47f975e7ea449a8c 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 4.6E-29 T 12-10-2018 TSC_c03950 f589aa908bb7c66d47f975e7ea449a8c 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 4.6E-29 T 12-10-2018 TSC_c03950 f589aa908bb7c66d47f975e7ea449a8c 443 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 4.6E-29 T 12-10-2018 TSC_c03950 f589aa908bb7c66d47f975e7ea449a8c 443 SUPERFAMILY SSF51905 2 316 1.08E-49 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c03950 f589aa908bb7c66d47f975e7ea449a8c 443 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 331 430 9.0E-14 T 12-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 TSC_c03950 f589aa908bb7c66d47f975e7ea449a8c 443 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 291 1.7E-65 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSC_c03950 f589aa908bb7c66d47f975e7ea449a8c 443 SUPERFAMILY SSF55424 322 441 7.9E-28 T 12-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 TSC_c19110 0554ca509acb32b4dee0eacda197c652 246 Gene3D G3DSA:3.40.50.300 3 236 1.4E-59 T 12-10-2018 TSC_c19110 0554ca509acb32b4dee0eacda197c652 246 SMART SM00382 28 218 8.7E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c19110 0554ca509acb32b4dee0eacda197c652 246 Pfam PF00005 ABC transporter 19 162 3.1E-26 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c19110 0554ca509acb32b4dee0eacda197c652 246 SUPERFAMILY SSF52540 3 223 2.28E-54 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c01880 46e50c36537f4bbba6f5f7789d5531f7 421 Gene3D G3DSA:3.30.499.20 4 262 4.9E-76 T 12-10-2018 TSC_c01880 46e50c36537f4bbba6f5f7789d5531f7 421 Pfam PF00330 Aconitase family (aconitate hydratase) 44 403 2.3E-84 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c01880 46e50c36537f4bbba6f5f7789d5531f7 421 ProSitePatterns PS01244 Aconitase family signature 2. 344 357 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TSC_c01880 46e50c36537f4bbba6f5f7789d5531f7 421 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 3 411 47.034 T 12-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TSC_c01880 46e50c36537f4bbba6f5f7789d5531f7 421 PRINTS PR00415 Aconitase family signature 288 299 3.0E-13 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c01880 46e50c36537f4bbba6f5f7789d5531f7 421 PRINTS PR00415 Aconitase family signature 344 357 3.0E-13 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c01880 46e50c36537f4bbba6f5f7789d5531f7 421 PRINTS PR00415 Aconitase family signature 124 139 3.0E-13 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c01880 46e50c36537f4bbba6f5f7789d5531f7 421 PRINTS PR00415 Aconitase family signature 110 123 3.0E-13 T 12-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 TSC_c01880 46e50c36537f4bbba6f5f7789d5531f7 421 SUPERFAMILY SSF53732 1 414 3.92E-129 T 12-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 TSC_c01880 46e50c36537f4bbba6f5f7789d5531f7 421 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 3 410 1.8E-186 T 12-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 TSC_c01880 46e50c36537f4bbba6f5f7789d5531f7 421 Gene3D G3DSA:3.30.499.10 265 420 3.2E-59 T 12-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 TSC_c01880 46e50c36537f4bbba6f5f7789d5531f7 421 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 409 4.9E-174 T 12-10-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 TSC_c01880 46e50c36537f4bbba6f5f7789d5531f7 421 ProSitePatterns PS00450 Aconitase family signature 1. 284 300 - T 12-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 TSC_c24970 3913598bfa0ad6482fc7c2aad935c64d 176 SUPERFAMILY SSF50324 4 173 8.9E-63 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSC_c24970 3913598bfa0ad6482fc7c2aad935c64d 176 Pfam PF00719 Inorganic pyrophosphatase 19 173 8.8E-54 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSC_c24970 3913598bfa0ad6482fc7c2aad935c64d 176 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 15 174 36.318 T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSC_c24970 3913598bfa0ad6482fc7c2aad935c64d 176 Gene3D G3DSA:3.90.80.10 2 175 5.3E-72 T 12-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSC_c24970 3913598bfa0ad6482fc7c2aad935c64d 176 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 12-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 TSC_c06210 509c92546f8b264ed523ebf9cd0ed906 378 Gene3D G3DSA:3.30.300.30 290 369 1.8E-5 T 12-10-2018 TSC_c06210 509c92546f8b264ed523ebf9cd0ed906 378 Pfam PF00501 AMP-binding enzyme 84 253 1.9E-7 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSC_c06210 509c92546f8b264ed523ebf9cd0ed906 378 SUPERFAMILY SSF56801 80 330 4.19E-27 T 12-10-2018 TSC_c06210 509c92546f8b264ed523ebf9cd0ed906 378 Gene3D G3DSA:3.40.50.12780 3 289 4.6E-57 T 12-10-2018 TSC_c12130 c260bbd42c162fb149941cff38759647 104 Gene3D G3DSA:3.30.70.100 1 104 2.2E-40 T 12-10-2018 TSC_c12130 c260bbd42c162fb149941cff38759647 104 SUPERFAMILY SSF54909 1 99 7.16E-32 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TSC_c12130 c260bbd42c162fb149941cff38759647 104 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 6.2E-23 T 12-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain TSC_c20360 d71b48d83beb9cbbb23d47700f625c8e 137 Pfam PF00011 Hsp20/alpha crystallin family 39 135 9.4E-22 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain TSC_c20360 d71b48d83beb9cbbb23d47700f625c8e 137 SUPERFAMILY SSF49764 31 134 1.46E-25 T 12-10-2018 IPR008978 HSP20-like chaperone TSC_c20360 d71b48d83beb9cbbb23d47700f625c8e 137 Gene3D G3DSA:2.60.40.790 2 135 5.3E-27 T 12-10-2018 IPR008978 HSP20-like chaperone TSC_c05270 832a4d4ab8d31630091b45708445e9f7 398 SUPERFAMILY SSF103473 12 395 1.96E-48 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c05270 832a4d4ab8d31630091b45708445e9f7 398 Gene3D G3DSA:1.20.1250.20 12 386 2.1E-40 T 12-10-2018 TSC_c05270 832a4d4ab8d31630091b45708445e9f7 398 Pfam PF05977 Transmembrane secretion effector 3 384 7.8E-57 T 12-10-2018 IPR010290 Transmembrane secretion effector TSC_c09780 e20f869292621a6355d4ffba02fa1004 176 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 4 174 1.9E-42 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 TSC_c09780 e20f869292621a6355d4ffba02fa1004 176 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 130 147 - T 12-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 TSC_c09780 e20f869292621a6355d4ffba02fa1004 176 Pfam PF00364 Biotin-requiring enzyme 100 173 5.6E-25 T 12-10-2018 IPR000089 Biotin/lipoyl attachment TSC_c09780 e20f869292621a6355d4ffba02fa1004 176 Gene3D G3DSA:2.40.50.100 97 173 1.1E-33 T 12-10-2018 TSC_c09780 e20f869292621a6355d4ffba02fa1004 176 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 135 148 1.6E-18 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 TSC_c09780 e20f869292621a6355d4ffba02fa1004 176 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 103 116 1.6E-18 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 TSC_c09780 e20f869292621a6355d4ffba02fa1004 176 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 120 134 1.6E-18 T 12-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 TSC_c09780 e20f869292621a6355d4ffba02fa1004 176 SUPERFAMILY SSF51230 98 173 5.5E-26 T 12-10-2018 IPR011053 Single hybrid motif TSC_c09660 a5af840dd64e0b2d75cc2fec50af6663 384 Gene3D G3DSA:1.20.1250.20 227 384 2.5E-19 T 12-10-2018 TSC_c09660 a5af840dd64e0b2d75cc2fec50af6663 384 Gene3D G3DSA:1.20.1250.20 4 226 6.7E-29 T 12-10-2018 TSC_c09660 a5af840dd64e0b2d75cc2fec50af6663 384 SUPERFAMILY SSF103473 6 383 3.4E-55 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c09660 a5af840dd64e0b2d75cc2fec50af6663 384 Pfam PF07690 Major Facilitator Superfamily 213 379 2.8E-16 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c09660 a5af840dd64e0b2d75cc2fec50af6663 384 Pfam PF07690 Major Facilitator Superfamily 11 206 3.4E-21 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c23340 092da78a54ac9c3056de9925c08a5918 203 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 3 190 8.4E-57 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TSC_c23340 092da78a54ac9c3056de9925c08a5918 203 SUPERFAMILY SSF52972 1 189 5.49E-67 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TSC_c23340 092da78a54ac9c3056de9925c08a5918 203 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 192 47.132 T 12-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 TSC_c23340 092da78a54ac9c3056de9925c08a5918 203 Gene3D G3DSA:3.90.950.10 1 192 2.5E-72 T 12-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like TSC_c23340 092da78a54ac9c3056de9925c08a5918 203 Pfam PF01725 Ham1 family 3 188 8.2E-57 T 12-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 TSC_c14120 6c9b546974cc2ac1c9c100f0fc26e353 257 PIRSF PIRSF017269 4 256 9.4E-60 T 12-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 TSC_c14120 6c9b546974cc2ac1c9c100f0fc26e353 257 SUPERFAMILY SSF53335 5 253 1.22E-61 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c14120 6c9b546974cc2ac1c9c100f0fc26e353 257 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 5 41 3.8E-8 T 12-10-2018 TSC_c14120 6c9b546974cc2ac1c9c100f0fc26e353 257 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 62 232 4.6E-17 T 12-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 TSC_c14120 6c9b546974cc2ac1c9c100f0fc26e353 257 Gene3D G3DSA:3.40.50.150 8 257 4.4E-79 T 12-10-2018 TSC_c01910 9436db1158625326fa9896810098daf9 54 Pfam PF08271 TFIIB zinc-binding 4 40 2.1E-9 T 12-10-2018 IPR013137 Zinc finger, TFIIB-type TSC_c01910 9436db1158625326fa9896810098daf9 54 TIGRFAM TIGR01206 lysW: lysine biosynthesis protein LysW 1 54 1.6E-32 T 12-10-2018 IPR005906 Lysine biosynthesis protein LysW TSC_c01910 9436db1158625326fa9896810098daf9 54 Gene3D G3DSA:2.20.28.160 1 54 7.0E-26 T 12-10-2018 TSC_c03980 76d9b2ce4e29653e120a3346b0c1364a 91 SUPERFAMILY SSF54909 1 86 4.54E-6 T 12-10-2018 IPR011008 Dimeric alpha-beta barrel TSC_c03980 76d9b2ce4e29653e120a3346b0c1364a 91 Pfam PF07978 NIPSNAP 3 86 8.3E-6 T 12-10-2018 IPR012577 NIPSNAP TSC_c09740 ba50ab726c69b6ed903da77b27e628bb 298 SUPERFAMILY SSF53474 37 296 2.16E-49 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c09740 ba50ab726c69b6ed903da77b27e628bb 298 Pfam PF12146 Serine aminopeptidase, S33 78 193 4.5E-12 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 TSC_c09740 ba50ab726c69b6ed903da77b27e628bb 298 Gene3D G3DSA:3.40.50.1820 28 296 1.8E-45 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c01820 5a335452e99291375a953017e4525d0b 193 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 9 188 3.5E-59 T 12-10-2018 IPR004507 Flavin prenyltransferase UbiX-like TSC_c01820 5a335452e99291375a953017e4525d0b 193 SUPERFAMILY SSF52507 9 190 9.29E-56 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TSC_c01820 5a335452e99291375a953017e4525d0b 193 Pfam PF02441 Flavoprotein 9 168 4.0E-24 T 12-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 TSC_c01820 5a335452e99291375a953017e4525d0b 193 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 8 190 34.194 T 12-10-2018 IPR004507 Flavin prenyltransferase UbiX-like TSC_c01820 5a335452e99291375a953017e4525d0b 193 Gene3D G3DSA:3.40.50.1950 9 192 1.1E-70 T 12-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 TSC_c19640 f0f5a887a9a7f6baa002a4d25a06c645 321 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 193 291 1.3E-18 T 12-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 TSC_c19640 f0f5a887a9a7f6baa002a4d25a06c645 321 Gene3D G3DSA:3.40.50.620 1 310 3.2E-68 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c19640 f0f5a887a9a7f6baa002a4d25a06c645 321 PIRSF PIRSF004976 1 303 5.6E-78 T 12-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 TSC_c19640 f0f5a887a9a7f6baa002a4d25a06c645 321 SUPERFAMILY SSF52402 25 224 8.16E-38 T 12-10-2018 TSC_c19640 f0f5a887a9a7f6baa002a4d25a06c645 321 Pfam PF01171 PP-loop family 50 221 1.0E-7 T 12-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 TSC_c21720 196ea4596b0bd10b185da5d371ee31d0 121 Gene3D G3DSA:1.20.1290.10 1 116 8.2E-35 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSC_c21720 196ea4596b0bd10b185da5d371ee31d0 121 SUPERFAMILY SSF69118 4 118 1.57E-30 T 12-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 TSC_c21720 196ea4596b0bd10b185da5d371ee31d0 121 Pfam PF02627 Carboxymuconolactone decarboxylase family 25 106 5.4E-20 T 12-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 TSC_c20650 1a65d59f39190f246dc0955e1d82d190 334 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 5 329 8.4E-103 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TSC_c20650 1a65d59f39190f246dc0955e1d82d190 334 SMART SM01329 4 327 3.8E-171 T 12-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 TSC_c20650 1a65d59f39190f246dc0955e1d82d190 334 Gene3D G3DSA:3.40.718.10 2 334 5.2E-153 T 12-10-2018 TSC_c20650 1a65d59f39190f246dc0955e1d82d190 334 SUPERFAMILY SSF53659 1 331 2.34E-117 T 12-10-2018 TSC_c02620 49e7c488db10d6cf584660cfaf083239 439 Pfam PF12704 MacB-like periplasmic core domain 49 278 2.0E-39 T 12-10-2018 IPR025857 MacB-like periplasmic core domain TSC_c02620 49e7c488db10d6cf584660cfaf083239 439 Pfam PF02687 FtsX-like permease family 345 432 2.6E-15 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TSC_c00360 4a2b07ba235f2f685aa62a2a2c170086 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 67 1.4E-28 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSC_c00360 4a2b07ba235f2f685aa62a2a2c170086 68 Gene3D G3DSA:2.40.50.140 1 68 4.9E-32 T 12-10-2018 TSC_c00360 4a2b07ba235f2f685aa62a2a2c170086 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 12-10-2018 IPR019844 Cold-shock conserved site TSC_c00360 4a2b07ba235f2f685aa62a2a2c170086 68 SMART SM00357 3 68 6.3E-30 T 12-10-2018 IPR011129 Cold shock domain GO:0003676 TSC_c00360 4a2b07ba235f2f685aa62a2a2c170086 68 PIRSF PIRSF002599 1 68 8.4E-24 T 12-10-2018 IPR012156 Cold shock, CspA GO:0003676 TSC_c00360 4a2b07ba235f2f685aa62a2a2c170086 68 SUPERFAMILY SSF50249 1 67 1.26E-22 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c00360 4a2b07ba235f2f685aa62a2a2c170086 68 PRINTS PR00050 Cold shock protein signature 39 57 2.6E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSC_c00360 4a2b07ba235f2f685aa62a2a2c170086 68 PRINTS PR00050 Cold shock protein signature 24 33 2.6E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSC_c00360 4a2b07ba235f2f685aa62a2a2c170086 68 PRINTS PR00050 Cold shock protein signature 4 19 2.6E-17 T 12-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 TSC_c12280 cccc96a1ce58ce5d8028f4a9f97ca852 87 Pfam PF00665 Integrase core domain 6 80 1.2E-8 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 TSC_c12280 cccc96a1ce58ce5d8028f4a9f97ca852 87 SUPERFAMILY SSF53098 9 82 5.16E-11 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c12280 cccc96a1ce58ce5d8028f4a9f97ca852 87 Gene3D G3DSA:3.30.420.10 1 78 8.3E-9 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSC_c14370 6881012404869553ceb9459e020ea8d5 135 Gene3D G3DSA:2.60.40.790 6 131 5.5E-24 T 12-10-2018 IPR008978 HSP20-like chaperone TSC_c14370 6881012404869553ceb9459e020ea8d5 135 Pfam PF00011 Hsp20/alpha crystallin family 42 128 1.2E-11 T 12-10-2018 IPR002068 Alpha crystallin/Hsp20 domain TSC_c14370 6881012404869553ceb9459e020ea8d5 135 SUPERFAMILY SSF49764 26 128 2.86E-22 T 12-10-2018 IPR008978 HSP20-like chaperone TSC_c04170 4e2871234582c527ba3ba4a329862023 72 Gene3D G3DSA:1.10.10.10 6 70 1.3E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c04170 4e2871234582c527ba3ba4a329862023 72 SUPERFAMILY SSF46689 1 68 3.94E-21 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSC_c04170 4e2871234582c527ba3ba4a329862023 72 Pfam PF04255 Protein of unknown function (DUF433) 7 61 4.8E-23 T 12-10-2018 IPR007367 Protein of unknown function DUF433 TSC_c07510 2651f4c35199ec0f875316fdf4ed8594 72 SUPERFAMILY SSF55229 23 71 9.29E-8 T 12-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 TSC_c07510 2651f4c35199ec0f875316fdf4ed8594 72 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 5 72 5.9E-21 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 TSC_c07510 2651f4c35199ec0f875316fdf4ed8594 72 Gene3D G3DSA:3.30.1070.10 11 72 2.0E-13 T 12-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 TSC_c07510 2651f4c35199ec0f875316fdf4ed8594 72 Pfam PF03776 Septum formation topological specificity factor MinE 7 72 1.8E-19 T 12-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 TSC_c17290 2e470010310a00e874f0e8be5ec0c8b0 277 Pfam PF01925 Sulfite exporter TauE/SafE 10 270 8.7E-38 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TSC_c19780 c91fe58fcaeb880ff71de8ddaa800ade 63 Pfam PF11127 Protein of unknown function (DUF2892) 1 62 2.3E-22 T 12-10-2018 IPR021309 Protein of unknown function DUF2892 TSC_c13690 a06b363bc1ff7c38ab1e2d53e9fef962 108 PIRSF PIRSF006639 1 108 7.9E-38 T 12-10-2018 IPR011379 NTP Pyrophosphohydrolase MazG-related, GP37 TSC_c13690 a06b363bc1ff7c38ab1e2d53e9fef962 108 Gene3D G3DSA:1.10.287.1080 1 100 3.5E-17 T 12-10-2018 TSC_c13690 a06b363bc1ff7c38ab1e2d53e9fef962 108 SUPERFAMILY SSF101386 1 96 6.71E-22 T 12-10-2018 TSC_c13690 a06b363bc1ff7c38ab1e2d53e9fef962 108 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 27 96 1.4E-13 T 12-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core TSC_c24560 dde912b95cd9ea19138344ebf738ffba 284 SUPERFAMILY SSF55729 1 131 2.03E-9 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSC_c24560 dde912b95cd9ea19138344ebf738ffba 284 Gene3D G3DSA:3.40.630.30 1 79 2.2E-6 T 12-10-2018 TSC_c24560 dde912b95cd9ea19138344ebf738ffba 284 SUPERFAMILY SSF55729 140 274 2.57E-24 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSC_c24560 dde912b95cd9ea19138344ebf738ffba 284 Gene3D G3DSA:3.40.630.30 145 275 1.0E-22 T 12-10-2018 TSC_c24560 dde912b95cd9ea19138344ebf738ffba 284 Pfam PF13673 Acetyltransferase (GNAT) domain 174 270 1.6E-14 T 12-10-2018 IPR000182 GNAT domain TSC_c01230 a6f216195375ead436b54f716f204564 131 Pfam PF01475 Ferric uptake regulator family 5 94 1.5E-23 T 12-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 TSC_c01230 a6f216195375ead436b54f716f204564 131 SUPERFAMILY SSF46785 5 123 2.09E-30 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c01230 a6f216195375ead436b54f716f204564 131 Gene3D G3DSA:3.30.1490.190 74 130 1.4E-10 T 12-10-2018 TSC_c01230 a6f216195375ead436b54f716f204564 131 Gene3D G3DSA:1.10.10.10 2 72 1.5E-20 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c05610 44c15b0be42fbe127624a33d56615879 613 Pfam PF01935 Domain of unknown function DUF87 191 406 1.2E-12 T 12-10-2018 IPR002789 Helicase HerA, central domain TSC_c05610 44c15b0be42fbe127624a33d56615879 613 SUPERFAMILY SSF52540 185 351 7.37E-5 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c05610 44c15b0be42fbe127624a33d56615879 613 Gene3D G3DSA:3.40.50.300 170 261 3.2E-9 T 12-10-2018 TSC_c05610 44c15b0be42fbe127624a33d56615879 613 Gene3D G3DSA:3.40.50.300 383 559 6.7E-15 T 12-10-2018 TSC_c05610 44c15b0be42fbe127624a33d56615879 613 SMART SM00382 188 536 8.5E-8 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c05610 44c15b0be42fbe127624a33d56615879 613 SUPERFAMILY SSF52540 157 551 9.8E-21 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c13590 8456dc27d4b1bd26ce881be3d98ca49e 131 Pfam PF01850 PIN domain 3 122 2.1E-12 T 12-10-2018 IPR002716 PIN domain TSC_c13590 8456dc27d4b1bd26ce881be3d98ca49e 131 Gene3D G3DSA:3.40.50.1010 2 128 2.9E-18 T 12-10-2018 TSC_c13590 8456dc27d4b1bd26ce881be3d98ca49e 131 SUPERFAMILY SSF88723 1 121 2.58E-20 T 12-10-2018 IPR029060 PIN-like domain superfamily TSC_c13590 8456dc27d4b1bd26ce881be3d98ca49e 131 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 129 11.653 T 12-10-2018 IPR022907 VapC family GO:0004540 TSC_c03610 756ac9790d7ecdfc5b1d3164e9aa29f5 233 Gene3D G3DSA:3.40.50.10320 3 231 2.5E-38 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TSC_c03610 756ac9790d7ecdfc5b1d3164e9aa29f5 233 SUPERFAMILY SSF102588 2 225 1.03E-44 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TSC_c03610 756ac9790d7ecdfc5b1d3164e9aa29f5 233 Pfam PF02585 GlcNAc-PI de-N-acetylase 5 156 5.5E-24 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TSC_c19660 5ab556343f543a19e64a350d4c2bde9b 374 PRINTS PR01272 Acetoin utilisation ACUC protein signature 77 91 5.4E-20 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 TSC_c19660 5ab556343f543a19e64a350d4c2bde9b 374 PRINTS PR01272 Acetoin utilisation ACUC protein signature 98 111 5.4E-20 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 TSC_c19660 5ab556343f543a19e64a350d4c2bde9b 374 PRINTS PR01272 Acetoin utilisation ACUC protein signature 263 279 5.4E-20 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 TSC_c19660 5ab556343f543a19e64a350d4c2bde9b 374 PRINTS PR01272 Acetoin utilisation ACUC protein signature 10 30 5.4E-20 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 TSC_c19660 5ab556343f543a19e64a350d4c2bde9b 374 PRINTS PR01272 Acetoin utilisation ACUC protein signature 301 320 5.4E-20 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 TSC_c19660 5ab556343f543a19e64a350d4c2bde9b 374 PRINTS PR01272 Acetoin utilisation ACUC protein signature 338 357 5.4E-20 T 12-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 TSC_c19660 5ab556343f543a19e64a350d4c2bde9b 374 Pfam PF00850 Histone deacetylase domain 16 303 2.7E-71 T 12-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSC_c19660 5ab556343f543a19e64a350d4c2bde9b 374 SUPERFAMILY SSF52768 1 328 3.36E-98 T 12-10-2018 IPR023696 Ureohydrolase domain superfamily TSC_c19660 5ab556343f543a19e64a350d4c2bde9b 374 Gene3D G3DSA:3.40.800.20 1 336 7.9E-98 T 12-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSC_c19660 5ab556343f543a19e64a350d4c2bde9b 374 PRINTS PR01270 Histone deacetylase superfamily signature 238 248 4.7E-19 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSC_c19660 5ab556343f543a19e64a350d4c2bde9b 374 PRINTS PR01270 Histone deacetylase superfamily signature 120 143 4.7E-19 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSC_c19660 5ab556343f543a19e64a350d4c2bde9b 374 PRINTS PR01270 Histone deacetylase superfamily signature 152 167 4.7E-19 T 12-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 TSC_c09580 aa82a029dc1627f14154ce479f68ba69 310 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 241 3.0E-62 T 12-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 TSC_c09580 aa82a029dc1627f14154ce479f68ba69 310 Gene3D G3DSA:3.90.25.10 175 303 5.2E-126 T 12-10-2018 TSC_c09580 aa82a029dc1627f14154ce479f68ba69 310 SUPERFAMILY SSF51735 1 309 5.19E-89 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c09580 aa82a029dc1627f14154ce479f68ba69 310 Gene3D G3DSA:3.40.50.720 3 243 5.2E-126 T 12-10-2018 TSC_c15270 732b897844355f5abcf1f349380259de 175 SUPERFAMILY SSF63848 70 172 6.28E-31 T 12-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 TSC_c15270 732b897844355f5abcf1f349380259de 175 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 73 170 8.5E-33 T 12-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 TSC_c15270 732b897844355f5abcf1f349380259de 175 Gene3D G3DSA:2.160.20.70 68 175 3.4E-40 T 12-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 TSC_c15270 732b897844355f5abcf1f349380259de 175 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 69 171 9.4E-29 T 12-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 TSC_c15880 04b916470006e9646737348f320c2989 350 SMART SM00471 166 302 3.6E-15 T 12-10-2018 IPR003607 HD/PDEase domain TSC_c15880 04b916470006e9646737348f320c2989 350 Gene3D G3DSA:1.10.3210.10 146 340 9.9E-72 T 12-10-2018 TSC_c15880 04b916470006e9646737348f320c2989 350 Pfam PF01966 HD domain 171 293 1.9E-22 T 12-10-2018 IPR006674 HD domain TSC_c15880 04b916470006e9646737348f320c2989 350 SUPERFAMILY SSF109604 158 333 7.59E-44 T 12-10-2018 TSC_c14050 e66cb38e05279c007a8f91e35de5ae61 212 Gene3D G3DSA:3.90.226.10 13 212 1.6E-85 T 12-10-2018 TSC_c14050 e66cb38e05279c007a8f91e35de5ae61 212 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 20 209 5.3E-95 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSC_c14050 e66cb38e05279c007a8f91e35de5ae61 212 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 107 118 - T 12-10-2018 IPR018215 ClpP, Ser active site TSC_c14050 e66cb38e05279c007a8f91e35de5ae61 212 SUPERFAMILY SSF52096 28 211 4.39E-74 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSC_c14050 e66cb38e05279c007a8f91e35de5ae61 212 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 129 142 - T 12-10-2018 IPR033135 ClpP, histidine active site TSC_c14050 e66cb38e05279c007a8f91e35de5ae61 212 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 20 210 43.882 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSC_c14050 e66cb38e05279c007a8f91e35de5ae61 212 PRINTS PR00127 Clp protease catalytic subunit P signature 76 96 9.5E-50 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSC_c14050 e66cb38e05279c007a8f91e35de5ae61 212 PRINTS PR00127 Clp protease catalytic subunit P signature 36 51 9.5E-50 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSC_c14050 e66cb38e05279c007a8f91e35de5ae61 212 PRINTS PR00127 Clp protease catalytic subunit P signature 185 204 9.5E-50 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSC_c14050 e66cb38e05279c007a8f91e35de5ae61 212 PRINTS PR00127 Clp protease catalytic subunit P signature 107 124 9.5E-50 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSC_c14050 e66cb38e05279c007a8f91e35de5ae61 212 PRINTS PR00127 Clp protease catalytic subunit P signature 128 147 9.5E-50 T 12-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 TSC_c14050 e66cb38e05279c007a8f91e35de5ae61 212 Pfam PF00574 Clp protease 30 209 1.8E-85 T 12-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA TSC_c20790 dc78076af31f34d0df9daf6866d82652 210 Pfam PF01553 Acyltransferase 47 151 4.5E-10 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TSC_c20790 dc78076af31f34d0df9daf6866d82652 210 SUPERFAMILY SSF69593 37 156 5.1E-19 T 12-10-2018 TSC_c20790 dc78076af31f34d0df9daf6866d82652 210 SMART SM00563 47 156 9.6E-23 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TSC_c05000 d07b1c5609bb28a9fda62318beea976d 390 Gene3D G3DSA:3.90.190.20 267 383 1.9E-15 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSC_c05000 d07b1c5609bb28a9fda62318beea976d 390 SUPERFAMILY SSF53623 1 263 3.21E-68 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSC_c05000 d07b1c5609bb28a9fda62318beea976d 390 SUPERFAMILY SSF53244 265 381 1.12E-17 T 12-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 TSC_c05000 d07b1c5609bb28a9fda62318beea976d 390 TIGRFAM TIGR01499 folC: bifunctional protein FolC 21 379 3.2E-82 T 12-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 TSC_c05000 d07b1c5609bb28a9fda62318beea976d 390 Pfam PF08245 Mur ligase middle domain 45 182 1.0E-7 T 12-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 TSC_c05000 d07b1c5609bb28a9fda62318beea976d 390 Gene3D G3DSA:3.40.1190.10 1 264 2.3E-72 T 12-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 TSC_c00340 874a0ef884ab9ebe823fc550fa96a95f 155 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 79 3.5E-8 T 12-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain TSC_c00340 874a0ef884ab9ebe823fc550fa96a95f 155 SUPERFAMILY SSF54534 2 136 1.96E-33 T 12-10-2018 TSC_c00340 874a0ef884ab9ebe823fc550fa96a95f 155 Gene3D G3DSA:3.10.50.40 1 155 1.4E-53 T 12-10-2018 TSC_c04800 c29185219584f6ab026dc24a951515d8 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 24 39 4.2E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c04800 c29185219584f6ab026dc24a951515d8 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 4.2E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c04800 c29185219584f6ab026dc24a951515d8 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 4.2E-12 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c04800 c29185219584f6ab026dc24a951515d8 113 Gene3D G3DSA:1.10.10.10 2 112 1.4E-26 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c04800 c29185219584f6ab026dc24a951515d8 113 SUPERFAMILY SSF46785 9 98 1.61E-22 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c04800 c29185219584f6ab026dc24a951515d8 113 SMART SM00418 22 99 3.2E-24 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c04800 c29185219584f6ab026dc24a951515d8 113 Pfam PF01022 Bacterial regulatory protein, arsR family 31 73 1.9E-11 T 12-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 TSC_c20710 e48c612c9bbc5e7f51cae51e4c7187ad 383 Gene3D G3DSA:3.60.150.10 1 383 4.2E-139 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TSC_c20710 e48c612c9bbc5e7f51cae51e4c7187ad 383 TIGRFAM TIGR00033 aroC: chorismate synthase 1 363 5.9E-112 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TSC_c20710 e48c612c9bbc5e7f51cae51e4c7187ad 383 Hamap MF_00300 Chorismate synthase [aroC]. 1 365 33.711 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TSC_c20710 e48c612c9bbc5e7f51cae51e4c7187ad 383 Pfam PF01264 Chorismate synthase 1 358 5.8E-108 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TSC_c20710 e48c612c9bbc5e7f51cae51e4c7187ad 383 ProSitePatterns PS00788 Chorismate synthase signature 2. 127 143 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TSC_c20710 e48c612c9bbc5e7f51cae51e4c7187ad 383 PIRSF PIRSF001456 1 379 3.7E-113 T 12-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TSC_c20710 e48c612c9bbc5e7f51cae51e4c7187ad 383 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 12-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TSC_c20710 e48c612c9bbc5e7f51cae51e4c7187ad 383 SUPERFAMILY SSF103263 1 380 2.09E-132 T 12-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 TSC_c19710 fc79b5ead5bcb951e8622e81319f9e36 327 Gene3D G3DSA:1.10.3720.10 79 326 1.7E-16 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c19710 fc79b5ead5bcb951e8622e81319f9e36 327 SUPERFAMILY SSF161098 91 313 7.19E-13 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c19710 fc79b5ead5bcb951e8622e81319f9e36 327 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 326 1.2E-31 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c08370 39979c547f32ea15a046ee551b3e7938 246 Pfam PF03741 Integral membrane protein TerC family 14 202 1.4E-48 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 TSC_c09620 d447b8ad045733086c717cdcc170a9dd 153 PRINTS PR01438 Universal stress protein signature 120 142 1.3E-15 T 12-10-2018 IPR006015 Universal stress protein A TSC_c09620 d447b8ad045733086c717cdcc170a9dd 153 PRINTS PR01438 Universal stress protein signature 2 20 1.3E-15 T 12-10-2018 IPR006015 Universal stress protein A TSC_c09620 d447b8ad045733086c717cdcc170a9dd 153 PRINTS PR01438 Universal stress protein signature 102 114 1.3E-15 T 12-10-2018 IPR006015 Universal stress protein A TSC_c09620 d447b8ad045733086c717cdcc170a9dd 153 Pfam PF00582 Universal stress protein family 1 142 3.1E-29 T 12-10-2018 IPR006016 UspA TSC_c09620 d447b8ad045733086c717cdcc170a9dd 153 SUPERFAMILY SSF52402 2 143 4.77E-36 T 12-10-2018 TSC_c09620 d447b8ad045733086c717cdcc170a9dd 153 Gene3D G3DSA:3.40.50.620 1 143 1.4E-35 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c03270 a0b74da383be75cb948a9c5439b00eb8 79 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.2E-16 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSC_c03270 a0b74da383be75cb948a9c5439b00eb8 79 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.2E-16 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSC_c03270 a0b74da383be75cb948a9c5439b00eb8 79 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.2E-16 T 12-10-2018 IPR000813 7Fe ferredoxin GO:0009055 TSC_c03270 a0b74da383be75cb948a9c5439b00eb8 79 Pfam PF00037 4Fe-4S binding domain 34 55 5.8E-10 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c03270 a0b74da383be75cb948a9c5439b00eb8 79 Gene3D G3DSA:3.30.70.20 2 78 2.3E-33 T 12-10-2018 TSC_c03270 a0b74da383be75cb948a9c5439b00eb8 79 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c03270 a0b74da383be75cb948a9c5439b00eb8 79 SUPERFAMILY SSF54862 1 74 8.63E-21 T 12-10-2018 TSC_c01220 f3a7730fa07ebf2965fa91bd06ca2449 301 Gene3D G3DSA:3.30.160.40 214 299 3.5E-25 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSC_c01220 f3a7730fa07ebf2965fa91bd06ca2449 301 SUPERFAMILY SSF54782 213 299 8.11E-24 T 12-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSC_c01220 f3a7730fa07ebf2965fa91bd06ca2449 301 PRINTS PR00151 Porphobilinogen deaminase signature 117 134 1.7E-30 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSC_c01220 f3a7730fa07ebf2965fa91bd06ca2449 301 PRINTS PR00151 Porphobilinogen deaminase signature 69 88 1.7E-30 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSC_c01220 f3a7730fa07ebf2965fa91bd06ca2449 301 PRINTS PR00151 Porphobilinogen deaminase signature 223 240 1.7E-30 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSC_c01220 f3a7730fa07ebf2965fa91bd06ca2449 301 PRINTS PR00151 Porphobilinogen deaminase signature 136 153 1.7E-30 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSC_c01220 f3a7730fa07ebf2965fa91bd06ca2449 301 Gene3D G3DSA:3.40.190.10 5 207 3.9E-81 T 12-10-2018 TSC_c01220 f3a7730fa07ebf2965fa91bd06ca2449 301 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 220 289 1.5E-19 T 12-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSC_c01220 f3a7730fa07ebf2965fa91bd06ca2449 301 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 291 36.384 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSC_c01220 f3a7730fa07ebf2965fa91bd06ca2449 301 PIRSF PIRSF001438 1 301 5.0E-111 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSC_c01220 f3a7730fa07ebf2965fa91bd06ca2449 301 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 291 3.8E-103 T 12-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSC_c01220 f3a7730fa07ebf2965fa91bd06ca2449 301 SUPERFAMILY SSF53850 2 208 7.06E-73 T 12-10-2018 TSC_c01220 f3a7730fa07ebf2965fa91bd06ca2449 301 Gene3D G3DSA:3.40.190.10 93 192 3.9E-81 T 12-10-2018 TSC_c01220 f3a7730fa07ebf2965fa91bd06ca2449 301 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 224 240 - T 12-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSC_c01220 f3a7730fa07ebf2965fa91bd06ca2449 301 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 203 9.8E-71 T 12-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 TSC_c08520 aa9dbcf165daf62f7925ed5b891c3ef4 200 Pfam PF02660 Glycerol-3-phosphate acyltransferase 10 184 1.4E-48 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TSC_c08520 aa9dbcf165daf62f7925ed5b891c3ef4 200 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 6 193 19.979 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TSC_c08520 aa9dbcf165daf62f7925ed5b891c3ef4 200 SMART SM01207 9 185 2.0E-76 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TSC_c08520 aa9dbcf165daf62f7925ed5b891c3ef4 200 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 5 194 1.2E-51 T 12-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 TSC_c00190 eb8eaf7442ae06c9b1a4b33776f23628 106 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 18 79 3.0E-8 T 12-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis TSC_c00190 eb8eaf7442ae06c9b1a4b33776f23628 106 Gene3D G3DSA:3.30.420.130 1 105 5.3E-13 T 12-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TSC_c00190 eb8eaf7442ae06c9b1a4b33776f23628 106 SUPERFAMILY SSF53146 1 78 9.94E-16 T 12-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily TSC_c14180 ac15d7676b098095748f2552aeb15bcb 196 SUPERFAMILY SSF110710 1 189 2.88E-73 T 12-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like TSC_c14180 ac15d7676b098095748f2552aeb15bcb 196 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 9 191 3.0E-75 T 12-10-2018 IPR006340 Protein of unknown function DUF436 TSC_c14180 ac15d7676b098095748f2552aeb15bcb 196 Pfam PF04260 Protein of unknown function (DUF436) 9 179 4.5E-68 T 12-10-2018 IPR006340 Protein of unknown function DUF436 TSC_c14180 ac15d7676b098095748f2552aeb15bcb 196 Hamap MF_00800 UPF0340 protein . 1 196 82.165 T 12-10-2018 IPR006340 Protein of unknown function DUF436 TSC_c14180 ac15d7676b098095748f2552aeb15bcb 196 Gene3D G3DSA:3.40.50.10360 1 196 2.4E-85 T 12-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like TSC_c14180 ac15d7676b098095748f2552aeb15bcb 196 PIRSF PIRSF007510 1 182 2.6E-67 T 12-10-2018 IPR006340 Protein of unknown function DUF436 TSC_c14180 ac15d7676b098095748f2552aeb15bcb 196 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 14 179 3.9E-60 T 12-10-2018 IPR006340 Protein of unknown function DUF436 TSC_c22190 6f5f62713ce7b629ec62c6aab5e6af0e 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 8 124 5.4E-55 T 12-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 TSC_c22190 6f5f62713ce7b629ec62c6aab5e6af0e 129 Pfam PF00411 Ribosomal protein S11 17 126 1.2E-42 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TSC_c22190 6f5f62713ce7b629ec62c6aab5e6af0e 129 PIRSF PIRSF002131 1 127 1.2E-51 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TSC_c22190 6f5f62713ce7b629ec62c6aab5e6af0e 129 Gene3D G3DSA:3.30.420.80 1 129 2.6E-57 T 12-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 TSC_c22190 6f5f62713ce7b629ec62c6aab5e6af0e 129 SUPERFAMILY SSF53137 12 127 8.5E-45 T 12-10-2018 TSC_c22190 6f5f62713ce7b629ec62c6aab5e6af0e 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 95 117 - T 12-10-2018 IPR018102 Ribosomal S11, conserved site TSC_c22190 6f5f62713ce7b629ec62c6aab5e6af0e 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 127 30.347 T 12-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 TSC_c09240 963160a4c15340b9318c613bff343098 162 SUPERFAMILY SSF54637 2 146 2.3E-34 T 12-10-2018 IPR029069 HotDog domain superfamily TSC_c09240 963160a4c15340b9318c613bff343098 162 Pfam PF03061 Thioesterase superfamily 54 138 1.1E-9 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TSC_c09240 963160a4c15340b9318c613bff343098 162 Gene3D G3DSA:3.10.129.10 1 150 4.2E-41 T 12-10-2018 TSC_c03520 1f06efff3f5f77224ae8e6825f11825a 362 Pfam PF01546 Peptidase family M20/M25/M40 64 349 2.1E-31 T 12-10-2018 IPR002933 Peptidase M20 GO:0016787 TSC_c03520 1f06efff3f5f77224ae8e6825f11825a 362 Gene3D G3DSA:3.40.630.10 16 342 2.3E-128 T 12-10-2018 TSC_c03520 1f06efff3f5f77224ae8e6825f11825a 362 SUPERFAMILY SSF53187 8 353 5.43E-45 T 12-10-2018 TSC_c03520 1f06efff3f5f77224ae8e6825f11825a 362 Hamap MF_01120 [LysW]-lysine/[LysW]-ornithine hydrolase [lysK]. 6 352 31.184 T 12-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 TSC_c03520 1f06efff3f5f77224ae8e6825f11825a 362 TIGRFAM TIGR01902 dapE-lys-deAc: N-acetyl-ornithine/N-acetyl-lysine deacetylase 10 352 2.1E-152 T 12-10-2018 IPR010175 [LysW]-lysine/[LysW]-ornithine hydrolase GO:0005737|GO:0008270|GO:0009085|GO:0016811|GO:0050897 TSC_c03520 1f06efff3f5f77224ae8e6825f11825a 362 Gene3D G3DSA:3.30.70.360 160 266 2.3E-128 T 12-10-2018 TSC_c00830 6f6b8c5b920dc5d353ada7acf52ff549 358 Pfam PF01882 Protein of unknown function DUF58 157 235 3.0E-10 T 12-10-2018 IPR002881 Domain of unknown function DUF58 TSC_c20430 77b33cadc813541eedeca842b901edae 150 SUPERFAMILY SSF54631 1 147 4.03E-33 T 12-10-2018 TSC_c20430 77b33cadc813541eedeca842b901edae 150 Gene3D G3DSA:3.10.580.10 1 150 5.9E-34 T 12-10-2018 TSC_c20430 77b33cadc813541eedeca842b901edae 150 Pfam PF00571 CBS domain 3 48 2.2E-10 T 12-10-2018 IPR000644 CBS domain TSC_c20430 77b33cadc813541eedeca842b901edae 150 Pfam PF00571 CBS domain 92 147 3.2E-14 T 12-10-2018 IPR000644 CBS domain TSC_c20430 77b33cadc813541eedeca842b901edae 150 SMART SM00116 10 58 0.019 T 12-10-2018 IPR000644 CBS domain TSC_c20430 77b33cadc813541eedeca842b901edae 150 SMART SM00116 99 147 6.2E-10 T 12-10-2018 IPR000644 CBS domain TSC_c23530 c5b2d22129b356b50a783dfe77012d29 240 SUPERFAMILY SSF56300 2 239 2.22E-50 T 12-10-2018 TSC_c23530 c5b2d22129b356b50a783dfe77012d29 240 PIRSF PIRSF000883 1 240 2.4E-46 T 12-10-2018 IPR011152 Phosphoesterase MJ0912 TSC_c23530 c5b2d22129b356b50a783dfe77012d29 240 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 200 3.0E-19 T 12-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 TSC_c23530 c5b2d22129b356b50a783dfe77012d29 240 Gene3D G3DSA:3.60.21.10 1 240 2.8E-53 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TSC_c03680 a1e3571939ed3f3b8b5beaf974841d28 176 Pfam PF05685 Putative restriction endonuclease 11 150 1.6E-31 T 12-10-2018 IPR008538 Domain of unknown function DUF820 TSC_c03680 a1e3571939ed3f3b8b5beaf974841d28 176 Gene3D G3DSA:3.90.1570.10 3 176 8.5E-20 T 12-10-2018 TSC_c03680 a1e3571939ed3f3b8b5beaf974841d28 176 SUPERFAMILY SSF52980 12 160 4.18E-27 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSC_c20510 7163dbc7926a9cdfec367cc70c640443 460 Pfam PF02589 LUD domain 69 291 2.9E-47 T 12-10-2018 IPR003741 LUD domain TSC_c20510 7163dbc7926a9cdfec367cc70c640443 460 Gene3D G3DSA:3.40.50.10420 148 292 1.8E-13 T 12-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily TSC_c20510 7163dbc7926a9cdfec367cc70c640443 460 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 310 321 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c20510 7163dbc7926a9cdfec367cc70c640443 460 SUPERFAMILY SSF46548 285 390 5.41E-18 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSC_c20510 7163dbc7926a9cdfec367cc70c640443 460 SUPERFAMILY SSF100950 62 292 2.05E-38 T 12-10-2018 IPR037171 NagB/RpiA transferase-like TSC_c20510 7163dbc7926a9cdfec367cc70c640443 460 Pfam PF13183 4Fe-4S dicluster domain 307 374 1.8E-10 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c20510 7163dbc7926a9cdfec367cc70c640443 460 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 22 421 1.7E-139 T 12-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 TSC_c20510 7163dbc7926a9cdfec367cc70c640443 460 Pfam PF11870 Domain of unknown function (DUF3390) 393 457 1.5E-12 T 12-10-2018 IPR024569 4Fe-4S binding protein, C-terminal TSC_c08260 a286874f7c73b8ef2cc9326e3c0ad104 549 Gene3D G3DSA:2.40.240.10 346 459 3.7E-35 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSC_c08260 a286874f7c73b8ef2cc9326e3c0ad104 549 Gene3D G3DSA:3.40.50.620 7 341 8.1E-130 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c08260 a286874f7c73b8ef2cc9326e3c0ad104 549 Gene3D G3DSA:2.40.240.10 460 544 6.6E-28 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSC_c08260 a286874f7c73b8ef2cc9326e3c0ad104 549 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 31 42 - T 12-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 TSC_c08260 a286874f7c73b8ef2cc9326e3c0ad104 549 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 27 546 1.5E-192 T 12-10-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 TSC_c08260 a286874f7c73b8ef2cc9326e3c0ad104 549 SUPERFAMILY SSF50715 338 544 1.78E-60 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSC_c08260 a286874f7c73b8ef2cc9326e3c0ad104 549 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 25 335 3.1E-101 T 12-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 TSC_c08260 a286874f7c73b8ef2cc9326e3c0ad104 549 PRINTS PR00987 Glutamyl-tRNA synthetase signature 28 40 6.9E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSC_c08260 a286874f7c73b8ef2cc9326e3c0ad104 549 PRINTS PR00987 Glutamyl-tRNA synthetase signature 202 212 6.9E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSC_c08260 a286874f7c73b8ef2cc9326e3c0ad104 549 PRINTS PR00987 Glutamyl-tRNA synthetase signature 42 53 6.9E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSC_c08260 a286874f7c73b8ef2cc9326e3c0ad104 549 PRINTS PR00987 Glutamyl-tRNA synthetase signature 57 70 6.9E-10 T 12-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 TSC_c08260 a286874f7c73b8ef2cc9326e3c0ad104 549 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 338 525 2.6E-47 T 12-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSC_c08260 a286874f7c73b8ef2cc9326e3c0ad104 549 SUPERFAMILY SSF52374 10 336 1.93E-91 T 12-10-2018 TSC_c05970 d4894df627b6b9a15f8404f44b86250a 182 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 98 109 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c05970 d4894df627b6b9a15f8404f44b86250a 182 SUPERFAMILY SSF54862 26 169 1.59E-29 T 12-10-2018 TSC_c05970 d4894df627b6b9a15f8404f44b86250a 182 Gene3D G3DSA:3.30.70.3270 26 182 3.5E-66 T 12-10-2018 TSC_c05970 d4894df627b6b9a15f8404f44b86250a 182 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 140 28.068 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05970 d4894df627b6b9a15f8404f44b86250a 182 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 9 136 4.2E-51 T 12-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05970 d4894df627b6b9a15f8404f44b86250a 182 Pfam PF12838 4Fe-4S dicluster domain 52 112 4.0E-14 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c08830 b19588bf33b2e2ca9701f18b5e1133bc 1099 SUPERFAMILY SSF82866 868 1092 6.02E-47 T 12-10-2018 TSC_c08830 b19588bf33b2e2ca9701f18b5e1133bc 1099 SUPERFAMILY SSF82693 628 724 5.23E-9 T 12-10-2018 TSC_c08830 b19588bf33b2e2ca9701f18b5e1133bc 1099 SUPERFAMILY SSF82714 185 265 1.44E-9 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSC_c08830 b19588bf33b2e2ca9701f18b5e1133bc 1099 SUPERFAMILY SSF82693 43 137 1.33E-26 T 12-10-2018 TSC_c08830 b19588bf33b2e2ca9701f18b5e1133bc 1099 Pfam PF00873 AcrB/AcrD/AcrF family 7 480 2.8E-120 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSC_c08830 b19588bf33b2e2ca9701f18b5e1133bc 1099 Pfam PF00873 AcrB/AcrD/AcrF family 571 1088 1.5E-94 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSC_c08830 b19588bf33b2e2ca9701f18b5e1133bc 1099 SUPERFAMILY SSF82693 139 322 5.41E-20 T 12-10-2018 TSC_c08830 b19588bf33b2e2ca9701f18b5e1133bc 1099 SUPERFAMILY SSF82866 291 487 5.23E-40 T 12-10-2018 TSC_c08830 b19588bf33b2e2ca9701f18b5e1133bc 1099 SUPERFAMILY SSF82714 785 866 5.36E-10 T 12-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains TSC_c08830 b19588bf33b2e2ca9701f18b5e1133bc 1099 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 7.7E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSC_c08830 b19588bf33b2e2ca9701f18b5e1133bc 1099 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 7.7E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSC_c08830 b19588bf33b2e2ca9701f18b5e1133bc 1099 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 7.7E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSC_c08830 b19588bf33b2e2ca9701f18b5e1133bc 1099 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 7.7E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSC_c08830 b19588bf33b2e2ca9701f18b5e1133bc 1099 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 7.7E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSC_c08830 b19588bf33b2e2ca9701f18b5e1133bc 1099 PRINTS PR00702 Acriflavin resistance protein family signature 13 37 7.7E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSC_c08830 b19588bf33b2e2ca9701f18b5e1133bc 1099 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 7.7E-39 T 12-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 TSC_c17080 d7ef91f4bafddc3c845df013eec3cee4 146 Gene3D G3DSA:1.10.10.10 54 94 4.9E-9 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c17080 d7ef91f4bafddc3c845df013eec3cee4 146 Hamap MF_01114 Regulatory protein RecX [recX]. 2 144 13.962 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 TSC_c17080 d7ef91f4bafddc3c845df013eec3cee4 146 Pfam PF02631 RecX family 33 138 1.1E-22 T 12-10-2018 IPR003783 Regulatory protein RecX GO:0006282 TSC_c05140 9d76eccfbfe39ddffeff73d293b5405b 414 SUPERFAMILY SSF56524 42 268 3.53E-57 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TSC_c05140 9d76eccfbfe39ddffeff73d293b5405b 414 Pfam PF00174 Oxidoreductase molybdopterin binding domain 99 257 4.2E-44 T 12-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 TSC_c05140 9d76eccfbfe39ddffeff73d293b5405b 414 Gene3D G3DSA:2.60.40.650 299 414 2.1E-30 T 12-10-2018 TSC_c05140 9d76eccfbfe39ddffeff73d293b5405b 414 SUPERFAMILY SSF81296 300 413 3.64E-29 T 12-10-2018 IPR014756 Immunoglobulin E-set TSC_c05140 9d76eccfbfe39ddffeff73d293b5405b 414 Gene3D G3DSA:3.90.420.10 34 277 2.4E-61 T 12-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 TSC_c05140 9d76eccfbfe39ddffeff73d293b5405b 414 Pfam PF03404 Mo-co oxidoreductase dimerisation domain 300 411 9.8E-12 T 12-10-2018 IPR005066 Moybdenum cofactor oxidoreductase, dimerisation GO:0016491|GO:0030151|GO:0055114 Reactome: R-HSA-1614517 TSC_c05140 9d76eccfbfe39ddffeff73d293b5405b 414 PRINTS PR00407 Eukaryotic molybdopterin domain signature 74 90 3.6E-15 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TSC_c05140 9d76eccfbfe39ddffeff73d293b5405b 414 PRINTS PR00407 Eukaryotic molybdopterin domain signature 156 171 3.6E-15 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TSC_c05140 9d76eccfbfe39ddffeff73d293b5405b 414 PRINTS PR00407 Eukaryotic molybdopterin domain signature 223 236 3.6E-15 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TSC_c05140 9d76eccfbfe39ddffeff73d293b5405b 414 PRINTS PR00407 Eukaryotic molybdopterin domain signature 239 252 3.6E-15 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TSC_c05140 9d76eccfbfe39ddffeff73d293b5405b 414 PRINTS PR00407 Eukaryotic molybdopterin domain signature 335 347 3.6E-15 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TSC_c05140 9d76eccfbfe39ddffeff73d293b5405b 414 PRINTS PR00407 Eukaryotic molybdopterin domain signature 206 222 3.6E-15 T 12-10-2018 IPR008335 Eukaryotic molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-1614517 TSC_c22600 9ab205971f5945077adf37b7b5afd1ac 178 SUPERFAMILY SSF53271 10 177 4.85E-50 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TSC_c22600 9ab205971f5945077adf37b7b5afd1ac 178 Gene3D G3DSA:3.40.50.2020 1 178 2.9E-61 T 12-10-2018 TSC_c22600 9ab205971f5945077adf37b7b5afd1ac 178 Pfam PF00156 Phosphoribosyl transferase domain 14 137 2.3E-23 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSC_c22600 9ab205971f5945077adf37b7b5afd1ac 178 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 173 3.3E-63 T 12-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 TSC_c09890 e739a8eeb4516a3d638eb0cf817ee165 282 Pfam PF07466 Protein of unknown function (DUF1517) 23 282 2.3E-44 T 12-10-2018 IPR010903 Protein of unknown function DUF1517 TSC_c10500 50ac942c9d5b702f51260ca05b8be322 584 Pfam PF02653 Branched-chain amino acid transport system / permease component 22 292 5.7E-39 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSC_c10500 50ac942c9d5b702f51260ca05b8be322 584 SUPERFAMILY SSF52540 333 579 1.58E-65 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c10500 50ac942c9d5b702f51260ca05b8be322 584 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 557 579 1.9E-10 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSC_c10500 50ac942c9d5b702f51260ca05b8be322 584 SMART SM00382 359 557 5.4E-11 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c10500 50ac942c9d5b702f51260ca05b8be322 584 Pfam PF00005 ABC transporter 352 508 9.0E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c10500 50ac942c9d5b702f51260ca05b8be322 584 Gene3D G3DSA:3.40.50.300 331 580 1.1E-63 T 12-10-2018 TSC_c10500 50ac942c9d5b702f51260ca05b8be322 584 ProSitePatterns PS00211 ABC transporters family signature. 481 495 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c18800 b84db79ae1dc5d724e6710d980747aa4 397 Gene3D G3DSA:1.10.3720.10 155 389 1.2E-55 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c18800 b84db79ae1dc5d724e6710d980747aa4 397 SUPERFAMILY SSF161098 4 397 6.67E-65 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c18800 b84db79ae1dc5d724e6710d980747aa4 397 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 208 385 1.2E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c15900 dbb9d1ad08493ad9f987c975104414a6 186 Pfam PF00872 Transposase, Mutator family 4 184 5.9E-42 T 12-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 TSC_c01370 49d4b873055e94614bf720038a751395 359 PIRSF PIRSF039026 1 355 1.1E-135 T 12-10-2018 IPR026289 Solute binding protein, mannitol/chloroaromatic system-like TSC_c01370 49d4b873055e94614bf720038a751395 359 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 25 1.7E-4 T 12-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal TSC_c01370 49d4b873055e94614bf720038a751395 359 Gene3D G3DSA:3.40.190.170 32 336 5.0E-133 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSC_c01370 49d4b873055e94614bf720038a751395 359 Gene3D G3DSA:3.40.190.10 152 322 5.0E-133 T 12-10-2018 TSC_c01370 49d4b873055e94614bf720038a751395 359 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 38 321 1.1E-65 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSC_c14980 f842eb58ca9f866a9f96aa93425604dd 279 Pfam PF01734 Patatin-like phospholipase 6 175 3.4E-25 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 TSC_c14980 f842eb58ca9f866a9f96aa93425604dd 279 Gene3D G3DSA:3.40.1090.10 2 93 3.7E-16 T 12-10-2018 TSC_c14980 f842eb58ca9f866a9f96aa93425604dd 279 Gene3D G3DSA:3.40.1090.10 95 195 5.7E-16 T 12-10-2018 TSC_c14980 f842eb58ca9f866a9f96aa93425604dd 279 SUPERFAMILY SSF52151 4 258 3.4E-47 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TSC_c05650 ac86202013746bda759e66726c5bb5da 242 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 5 242 6.8E-99 T 12-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 TSC_c05650 ac86202013746bda759e66726c5bb5da 242 SMART SM00382 29 223 2.7E-9 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c05650 ac86202013746bda759e66726c5bb5da 242 Pfam PF00005 ABC transporter 21 165 2.1E-32 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c05650 ac86202013746bda759e66726c5bb5da 242 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c05650 ac86202013746bda759e66726c5bb5da 242 SUPERFAMILY SSF52540 5 239 1.17E-66 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c05650 ac86202013746bda759e66726c5bb5da 242 Gene3D G3DSA:3.40.50.300 4 242 7.7E-69 T 12-10-2018 TSC_c13250 840bdf4997df7fb8c68672a9c23745d6 193 Gene3D G3DSA:3.40.630.20 1 192 8.6E-62 T 12-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 TSC_c13250 840bdf4997df7fb8c68672a9c23745d6 193 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 76 96 5.6E-25 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSC_c13250 840bdf4997df7fb8c68672a9c23745d6 193 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 58 70 5.6E-25 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSC_c13250 840bdf4997df7fb8c68672a9c23745d6 193 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 128 144 5.6E-25 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSC_c13250 840bdf4997df7fb8c68672a9c23745d6 193 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 2 25 5.6E-25 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSC_c13250 840bdf4997df7fb8c68672a9c23745d6 193 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 155 167 5.6E-25 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSC_c13250 840bdf4997df7fb8c68672a9c23745d6 193 PIRSF PIRSF015592 1 193 1.0E-47 T 12-10-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 MetaCyc: PWY-7942 TSC_c13250 840bdf4997df7fb8c68672a9c23745d6 193 Pfam PF01470 Pyroglutamyl peptidase 2 187 3.3E-38 T 12-10-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like MetaCyc: PWY-7942 TSC_c13250 840bdf4997df7fb8c68672a9c23745d6 193 SUPERFAMILY SSF53182 2 192 1.05E-49 T 12-10-2018 IPR036440 Peptidase C15, pyroglutamyl peptidase I-like superfamily MetaCyc: PWY-7942 TSC_c00210 d428c611acfd2fe36e9c51d30bff2c49 142 SUPERFAMILY SSF46626 21 127 9.89E-22 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c00210 d428c611acfd2fe36e9c51d30bff2c49 142 Gene3D G3DSA:1.10.760.10 18 141 1.4E-42 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c00210 d428c611acfd2fe36e9c51d30bff2c49 142 Pfam PF00034 Cytochrome c 20 106 5.6E-10 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c02890 7c280814505986732927c2b97fb700ba 282 Gene3D G3DSA:1.20.120.20 6 136 2.5E-10 T 12-10-2018 TSC_c02890 7c280814505986732927c2b97fb700ba 282 Gene3D G3DSA:1.20.120.20 141 264 2.5E-6 T 12-10-2018 TSC_c02890 7c280814505986732927c2b97fb700ba 282 SUPERFAMILY SSF58113 12 126 5.23E-5 T 12-10-2018 TSC_c02890 7c280814505986732927c2b97fb700ba 282 Pfam PF12128 Protein of unknown function (DUF3584) 7 254 8.8E-9 T 12-10-2018 IPR021979 Protein of unknown function DUF3584 TSC_c02890 7c280814505986732927c2b97fb700ba 282 SUPERFAMILY SSF58113 111 263 5.23E-9 T 12-10-2018 TSC_c03570 f2d1f66252cd6a543f42abeb23dc3b92 125 Pfam PF00575 S1 RNA binding domain 3 74 2.7E-16 T 12-10-2018 IPR003029 S1 domain GO:0003676 TSC_c03570 f2d1f66252cd6a543f42abeb23dc3b92 125 Gene3D G3DSA:2.40.50.140 1 83 7.6E-26 T 12-10-2018 TSC_c03570 f2d1f66252cd6a543f42abeb23dc3b92 125 SUPERFAMILY SSF50249 4 80 5.68E-22 T 12-10-2018 IPR012340 Nucleic acid-binding, OB-fold TSC_c03570 f2d1f66252cd6a543f42abeb23dc3b92 125 SMART SM00316 4 74 3.6E-21 T 12-10-2018 IPR022967 RNA-binding domain, S1 TSC_c19550 c8a23db3665628bd3bb2d8a6f4aa5a18 382 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 182 193 - T 12-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site TSC_c19550 c8a23db3665628bd3bb2d8a6f4aa5a18 382 SUPERFAMILY SSF46548 129 245 2.3E-16 T 12-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 TSC_c19550 c8a23db3665628bd3bb2d8a6f4aa5a18 382 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 27 330 5.6E-74 T 12-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 TSC_c19550 c8a23db3665628bd3bb2d8a6f4aa5a18 382 Pfam PF08331 Domain of unknown function (DUF1730) 55 128 3.2E-10 T 12-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 TSC_c19550 c8a23db3665628bd3bb2d8a6f4aa5a18 382 SUPERFAMILY SSF48371 294 378 9.79E-6 T 12-10-2018 IPR016024 Armadillo-type fold TSC_c19550 c8a23db3665628bd3bb2d8a6f4aa5a18 382 Pfam PF13484 4Fe-4S double cluster binding domain 181 244 9.7E-18 T 12-10-2018 TSC_c11870 fed07ee2ae5b41b1f5546aeefa85e415 537 Gene3D G3DSA:3.30.300.310 429 533 1.9E-41 T 12-10-2018 TSC_c11870 fed07ee2ae5b41b1f5546aeefa85e415 537 Pfam PF13193 AMP-binding enzyme C-terminal domain 443 517 2.7E-19 T 12-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain TSC_c11870 fed07ee2ae5b41b1f5546aeefa85e415 537 Pfam PF00501 AMP-binding enzyme 17 433 4.1E-97 T 12-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 TSC_c11870 fed07ee2ae5b41b1f5546aeefa85e415 537 SUPERFAMILY SSF56801 3 530 4.97E-149 T 12-10-2018 TSC_c11870 fed07ee2ae5b41b1f5546aeefa85e415 537 Gene3D G3DSA:3.40.50.12780 1 428 2.4E-173 T 12-10-2018 TSC_c20010 8d9c8939cc34c900dea744f72c429524 77 SUPERFAMILY SSF46689 4 65 1.29E-19 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSC_c20010 8d9c8939cc34c900dea744f72c429524 77 Pfam PF04255 Protein of unknown function (DUF433) 7 60 1.4E-21 T 12-10-2018 IPR007367 Protein of unknown function DUF433 TSC_c20010 8d9c8939cc34c900dea744f72c429524 77 Gene3D G3DSA:1.10.10.10 5 67 1.4E-16 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c01130 20fabd8c47943bf34f23c32c4ace3e48 97 Gene3D G3DSA:3.30.460.10 2 96 3.7E-20 T 12-10-2018 TSC_c01130 20fabd8c47943bf34f23c32c4ace3e48 97 SUPERFAMILY SSF81301 2 90 3.0E-23 T 12-10-2018 TSC_c01130 20fabd8c47943bf34f23c32c4ace3e48 97 Pfam PF01909 Nucleotidyltransferase domain 12 90 1.1E-14 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSC_c11010 6cf5069e3eab1b20110f6398c78071e0 372 Gene3D G3DSA:1.20.1250.20 3 186 4.5E-12 T 12-10-2018 TSC_c11010 6cf5069e3eab1b20110f6398c78071e0 372 Pfam PF07690 Major Facilitator Superfamily 31 301 5.4E-9 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c11010 6cf5069e3eab1b20110f6398c78071e0 372 Gene3D G3DSA:1.20.1250.20 199 372 2.9E-8 T 12-10-2018 TSC_c11010 6cf5069e3eab1b20110f6398c78071e0 372 SUPERFAMILY SSF103473 5 369 1.57E-26 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c07570 131f4e25790577337100597ca04c7fff 130 SUPERFAMILY SSF46626 16 111 6.16E-16 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c07570 131f4e25790577337100597ca04c7fff 130 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 20 95 6.8E-9 T 12-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c07570 131f4e25790577337100597ca04c7fff 130 Gene3D G3DSA:1.10.760.10 12 124 5.1E-16 T 12-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 TSC_c07120 2d7171f6d9b46c94c6dc8c22a9bce5c4 207 Pfam PF00583 Acetyltransferase (GNAT) family 32 179 3.0E-15 T 12-10-2018 IPR000182 GNAT domain TSC_c07120 2d7171f6d9b46c94c6dc8c22a9bce5c4 207 SUPERFAMILY SSF55729 4 186 5.98E-27 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSC_c07120 2d7171f6d9b46c94c6dc8c22a9bce5c4 207 Gene3D G3DSA:3.40.630.30 2 190 3.8E-35 T 12-10-2018 TSC_c21790 58802e4e712e41d2a427b9abc8882eb5 231 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 230 30.164 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSC_c21790 58802e4e712e41d2a427b9abc8882eb5 231 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 228 3.6E-62 T 12-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 TSC_c21790 58802e4e712e41d2a427b9abc8882eb5 231 ProSitePatterns PS01058 SAICAR synthetase signature 2. 169 177 - T 12-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSC_c21790 58802e4e712e41d2a427b9abc8882eb5 231 SUPERFAMILY SSF56104 1 228 1.6E-79 T 12-10-2018 TSC_c21790 58802e4e712e41d2a427b9abc8882eb5 231 Pfam PF01259 SAICAR synthetase 3 227 2.0E-59 T 12-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 TSC_c21790 58802e4e712e41d2a427b9abc8882eb5 231 Gene3D G3DSA:3.30.200.20 3 227 1.5E-87 T 12-10-2018 TSC_c21790 58802e4e712e41d2a427b9abc8882eb5 231 Gene3D G3DSA:3.30.470.20 81 216 1.5E-87 T 12-10-2018 TSC_c13730 059893400509f1f5483e59643a6bf55d 311 SUPERFAMILY SSF53098 20 262 9.86E-10 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c06270 5a32855020694afc79bc462ff30a9e2d 231 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 8 222 3.8E-67 T 12-10-2018 IPR022493 Integral membrane YkoY TSC_c06270 5a32855020694afc79bc462ff30a9e2d 231 Pfam PF03741 Integral membrane protein TerC family 12 182 6.9E-48 T 12-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 TSC_c09830 9d75cecd14f0ed2db6b2c13a34f945c0 151 Pfam PF02681 Divergent PAP2 family 5 139 8.9E-51 T 12-10-2018 IPR003832 Protein of unknown function DUF212 TSC_c05090 780e846ab93f09cac017c7e567f5d1f1 390 Pfam PF13458 Periplasmic binding protein 24 368 2.7E-55 T 12-10-2018 IPR028081 Leucine-binding protein domain TSC_c05090 780e846ab93f09cac017c7e567f5d1f1 390 Gene3D G3DSA:3.40.50.2300 31 354 1.9E-92 T 12-10-2018 TSC_c05090 780e846ab93f09cac017c7e567f5d1f1 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 65 83 3.0E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSC_c05090 780e846ab93f09cac017c7e567f5d1f1 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 46 62 3.0E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSC_c05090 780e846ab93f09cac017c7e567f5d1f1 390 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 24 40 3.0E-6 T 12-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 TSC_c05090 780e846ab93f09cac017c7e567f5d1f1 390 SUPERFAMILY SSF53822 23 373 9.76E-83 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TSC_c05090 780e846ab93f09cac017c7e567f5d1f1 390 Gene3D G3DSA:3.40.50.2300 143 273 1.9E-92 T 12-10-2018 TSC_c04030 d37924c9bc770239cc606860f72a8e21 128 Gene3D G3DSA:3.30.420.140 1 126 4.2E-27 T 12-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 TSC_c04030 d37924c9bc770239cc606860f72a8e21 128 SMART SM00732 1 93 2.7E-7 T 12-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 TSC_c04030 d37924c9bc770239cc606860f72a8e21 128 SUPERFAMILY SSF53098 1 125 7.78E-24 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c04030 d37924c9bc770239cc606860f72a8e21 128 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 1 124 6.6E-16 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TSC_c04030 d37924c9bc770239cc606860f72a8e21 128 Pfam PF03652 Holliday junction resolvase 1 125 1.1E-26 T 12-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 TSC_c00770 47bf1d4a9f526ab62af13873ad2c330b 153 Gene3D G3DSA:3.40.50.1010 4 133 2.9E-22 T 12-10-2018 TSC_c00770 47bf1d4a9f526ab62af13873ad2c330b 153 SUPERFAMILY SSF88723 5 130 3.36E-14 T 12-10-2018 IPR029060 PIN-like domain superfamily TSC_c00770 47bf1d4a9f526ab62af13873ad2c330b 153 Pfam PF01850 PIN domain 5 126 1.0E-6 T 12-10-2018 IPR002716 PIN domain TSC_c02300 b81763213faf5357a7808a7c07cf640a 123 Pfam PF11255 Protein of unknown function (DUF3054) 13 116 3.0E-15 T 12-10-2018 IPR021414 Protein of unknown function DUF3054 TSC_c24180 a606d3cdeba43fc7de8050f3001aa662 362 SUPERFAMILY SSF144052 5 354 3.27E-93 T 12-10-2018 TSC_c24180 a606d3cdeba43fc7de8050f3001aa662 362 Pfam PF02073 Thermophilic metalloprotease (M29) 4 336 3.7E-63 T 12-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 TSC_c07250 6dfe65a33733a14d0e5324d7e231469b 382 Pfam PF04055 Radical SAM superfamily 65 236 2.6E-11 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSC_c07250 6dfe65a33733a14d0e5324d7e231469b 382 TIGRFAM TIGR03700 mena_SCO4494: putative menaquinone biosynthesis radical SAM enzyme, SCO4494 family 12 364 1.3E-165 T 12-10-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 TSC_c07250 6dfe65a33733a14d0e5324d7e231469b 382 SUPERFAMILY SSF102114 19 357 6.93E-52 T 12-10-2018 TSC_c07250 6dfe65a33733a14d0e5324d7e231469b 382 PIRSF PIRSF004762 2 377 4.1E-109 T 12-10-2018 TSC_c07250 6dfe65a33733a14d0e5324d7e231469b 382 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 56 364 3.3E-105 T 12-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 TSC_c07250 6dfe65a33733a14d0e5324d7e231469b 382 SMART SM00729 59 273 4.0E-4 T 12-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 TSC_c07250 6dfe65a33733a14d0e5324d7e231469b 382 Gene3D G3DSA:3.20.20.70 11 358 3.0E-51 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c07250 6dfe65a33733a14d0e5324d7e231469b 382 Hamap MF_00993 Aminodeoxyfutalosine synthase [mqnE]. 10 367 51.851 T 12-10-2018 IPR022432 Aminodeoxyfutalosine synthase GO:0009234 KEGG: 00130+2.5.1.120|MetaCyc: PWY-7371|MetaCyc: PWY-7374 TSC_c24190 2e722226268ad881328721b4be084fd1 371 Pfam PF02817 e3 binding domain 5 39 6.9E-13 T 12-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 TSC_c24190 2e722226268ad881328721b4be084fd1 371 SUPERFAMILY SSF47005 5 43 3.53E-10 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TSC_c24190 2e722226268ad881328721b4be084fd1 371 Gene3D G3DSA:4.10.320.10 5 48 3.0E-15 T 12-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 TSC_c12060 41e806b14d75ad2f12d5f2d358cd90f3 410 Pfam PF13416 Bacterial extracellular solute-binding protein 48 340 1.4E-29 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSC_c12060 41e806b14d75ad2f12d5f2d358cd90f3 410 Gene3D G3DSA:3.40.190.10 17 407 2.7E-68 T 12-10-2018 TSC_c12060 41e806b14d75ad2f12d5f2d358cd90f3 410 SUPERFAMILY SSF53850 19 406 4.14E-62 T 12-10-2018 TSC_c01510 275b2708f965a072969c6ad329e209e6 209 SMART SM00855 3 155 5.6E-27 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSC_c01510 275b2708f965a072969c6ad329e209e6 209 PIRSF PIRSF000709 1 188 4.4E-21 T 12-10-2018 TSC_c01510 275b2708f965a072969c6ad329e209e6 209 SUPERFAMILY SSF53254 1 186 1.24E-61 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TSC_c01510 275b2708f965a072969c6ad329e209e6 209 Gene3D G3DSA:3.40.50.1240 1 203 2.2E-60 T 12-10-2018 IPR029033 Histidine phosphatase superfamily TSC_c01510 275b2708f965a072969c6ad329e209e6 209 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 185 1.8E-58 T 12-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 TSC_c01510 275b2708f965a072969c6ad329e209e6 209 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 6 15 - T 12-10-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824 TSC_c08240 736eb819ee204d695cd81ec93e1c8d24 101 Gene3D G3DSA:3.40.1350.90 1 101 2.1E-45 T 12-10-2018 TSC_c08240 736eb819ee204d695cd81ec93e1c8d24 101 Pfam PF11572 Protein of unknown function (DUF3234) 4 95 1.6E-38 T 12-10-2018 IPR021628 Protein of unknown function DUF3234 TSC_c22040 049a923df7a6697d15ea3eddb5082dd4 173 Pfam PF13302 Acetyltransferase (GNAT) domain 18 148 2.6E-22 T 12-10-2018 IPR000182 GNAT domain TSC_c22040 049a923df7a6697d15ea3eddb5082dd4 173 SUPERFAMILY SSF55729 18 153 3.85E-29 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSC_c22040 049a923df7a6697d15ea3eddb5082dd4 173 Gene3D G3DSA:3.40.630.30 5 172 8.9E-34 T 12-10-2018 TSC_c24800 ddadfcc3febe2d426bfa70d198b513c3 62 SUPERFAMILY SSF47598 5 52 3.71E-11 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TSC_c24800 ddadfcc3febe2d426bfa70d198b513c3 62 Gene3D G3DSA:1.10.1220.10 3 51 1.4E-8 T 12-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 TSC_c21750 9ba879be4a2c6616fce11fbf8a04e259 192 SUPERFAMILY SSF49482 14 170 3.79E-45 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 TSC_c21750 9ba879be4a2c6616fce11fbf8a04e259 192 Gene3D G3DSA:2.60.130.10 4 167 3.0E-46 T 12-10-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 TSC_c21750 9ba879be4a2c6616fce11fbf8a04e259 192 Pfam PF00775 Dioxygenase 28 117 6.4E-10 T 12-10-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 TSC_c17700 5a9b049cdf20fbe217bfb753187f027b 366 Pfam PF14256 YwiC-like protein 14 144 3.9E-21 T 12-10-2018 IPR025576 YwiC-like protein TSC_c22260 e2babbfdc561b51b0ad4cb56f6d7e12f 60 Gene3D G3DSA:3.30.1390.20 1 60 2.3E-24 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TSC_c22260 e2babbfdc561b51b0ad4cb56f6d7e12f 60 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 57 3.1E-25 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22260 e2babbfdc561b51b0ad4cb56f6d7e12f 60 PIRSF PIRSF002211 1 60 6.1E-25 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22260 e2babbfdc561b51b0ad4cb56f6d7e12f 60 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 16.701 T 12-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22260 e2babbfdc561b51b0ad4cb56f6d7e12f 60 SUPERFAMILY SSF55129 1 59 2.75E-18 T 12-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily TSC_c22260 e2babbfdc561b51b0ad4cb56f6d7e12f 60 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 4.1E-16 T 12-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain TSC_c13510 9b5329360faf533a6e5fc9f6e462cedd 303 Pfam PF00005 ABC transporter 18 160 5.2E-25 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c13510 9b5329360faf533a6e5fc9f6e462cedd 303 SUPERFAMILY SSF52540 3 226 5.33E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c13510 9b5329360faf533a6e5fc9f6e462cedd 303 Gene3D G3DSA:3.40.50.300 1 227 7.9E-57 T 12-10-2018 TSC_c13510 9b5329360faf533a6e5fc9f6e462cedd 303 SMART SM00382 27 209 6.9E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c05750 227bc306670b662316c8bb5b0bc0c7ba 355 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 330 4.0E-44 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSC_c09530 ad54c9b3c034d9b77df6809814b992f2 249 Pfam PF00005 ABC transporter 22 176 2.7E-28 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c09530 ad54c9b3c034d9b77df6809814b992f2 249 SUPERFAMILY SSF52540 4 247 1.54E-62 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c09530 ad54c9b3c034d9b77df6809814b992f2 249 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 229 247 1.3E-5 T 12-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal TSC_c09530 ad54c9b3c034d9b77df6809814b992f2 249 SMART SM00382 29 225 8.2E-10 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c09530 ad54c9b3c034d9b77df6809814b992f2 249 Gene3D G3DSA:3.40.50.300 3 249 4.7E-61 T 12-10-2018 TSC_c08340 63e1da1673a638608c907acf458b5f22 225 SUPERFAMILY SSF53167 29 198 5.98E-23 T 12-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 TSC_c08340 63e1da1673a638608c907acf458b5f22 225 TIGRFAM TIGR03664 fut_nucase: futalosine hydrolase 3 212 2.8E-53 T 12-10-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 TSC_c08340 63e1da1673a638608c907acf458b5f22 225 Hamap MF_00991 Futalosine hydrolase [mqnB]. 14 216 22.77 T 12-10-2018 IPR019963 Futalosine hydrolase GO:0009234|GO:0016799 KEGG: 00130+3.2.2.26|MetaCyc: PWY-7374 TSC_c08340 63e1da1673a638608c907acf458b5f22 225 Gene3D G3DSA:3.40.50.1580 22 215 2.2E-27 T 12-10-2018 TSC_c08340 63e1da1673a638608c907acf458b5f22 225 Pfam PF01048 Phosphorylase superfamily 30 195 2.1E-18 T 12-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 TSC_c24040 2c756a21c9189bb3338ed077974f85d9 288 Pfam PF08823 Putative peptidoglycan binding domain 212 281 3.0E-19 T 12-10-2018 IPR014927 Putative peptidoglycan binding TSC_c24040 2c756a21c9189bb3338ed077974f85d9 288 SUPERFAMILY SSF56235 5 215 2.24E-71 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSC_c24040 2c756a21c9189bb3338ed077974f85d9 288 Gene3D G3DSA:3.60.20.10 2 215 4.0E-78 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSC_c24040 2c756a21c9189bb3338ed077974f85d9 288 Pfam PF06267 Family of unknown function (DUF1028) 5 200 4.5E-76 T 12-10-2018 IPR010430 Protein of unknown function DUF1028 TSC_c09590 633e7bf2ab112c5f1ff5b50094c80dab 188 SUPERFAMILY SSF52833 5 183 3.44E-50 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TSC_c09590 633e7bf2ab112c5f1ff5b50094c80dab 188 Pfam PF00578 AhpC/TSA family 13 131 1.6E-16 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSC_c09590 633e7bf2ab112c5f1ff5b50094c80dab 188 Gene3D G3DSA:3.40.30.10 2 188 7.2E-55 T 12-10-2018 TSC_c14240 b2b0f69f4f72389077554f17834a9b40 284 Pfam PF00146 NADH dehydrogenase 12 252 1.1E-19 T 12-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c07830 e19bfd3fe503c40ff35669b610e89ce9 88 Gene3D G3DSA:3.30.70.100 1 88 1.4E-34 T 12-10-2018 TSC_c07830 e19bfd3fe503c40ff35669b610e89ce9 88 Pfam PF00708 Acylphosphatase 6 85 5.9E-28 T 12-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSC_c07830 e19bfd3fe503c40ff35669b610e89ce9 88 SUPERFAMILY SSF54975 2 87 3.27E-27 T 12-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 TSC_c23820 84205e45b416fc5dc298819127ac5ddf 350 Pfam PF04055 Radical SAM superfamily 85 250 5.5E-21 T 12-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 TSC_c23820 84205e45b416fc5dc298819127ac5ddf 350 PIRSF PIRSF004869 3 325 1.4E-105 T 12-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted TSC_c23820 84205e45b416fc5dc298819127ac5ddf 350 Gene3D G3DSA:3.20.20.70 71 298 3.4E-35 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c23820 84205e45b416fc5dc298819127ac5ddf 350 SUPERFAMILY SSF102114 54 327 1.06E-35 T 12-10-2018 TSC_c23820 84205e45b416fc5dc298819127ac5ddf 350 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 17 348 1.1E-109 T 12-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme TSC_c12160 cd709860650f2a2439be1f64f72e4ec5 173 Pfam PF06243 Phenylacetic acid degradation B 5 168 2.0E-35 T 12-10-2018 IPR009359 Phenylacetic acid degradation B TSC_c12160 cd709860650f2a2439be1f64f72e4ec5 173 Gene3D G3DSA:3.10.20.520 2 64 4.7E-17 T 12-10-2018 IPR038693 Phenylacetyl-CoA epoxidase, subunit B TSC_c06030 5ae3747be6e671fcff4754ab028119a0 206 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 30 154 1.1E-37 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06030 5ae3747be6e671fcff4754ab028119a0 206 SUPERFAMILY SSF143243 6 183 4.32E-51 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06030 5ae3747be6e671fcff4754ab028119a0 206 Gene3D G3DSA:3.30.460.80 1 134 5.8E-50 T 12-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06030 5ae3747be6e671fcff4754ab028119a0 206 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 86 137 6.0E-23 T 12-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06030 5ae3747be6e671fcff4754ab028119a0 206 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 115 136 - T 12-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06030 5ae3747be6e671fcff4754ab028119a0 206 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 3 162 30.154 T 12-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c12140 7cfb923d43ed20f14df07f21a62145a1 195 Gene3D G3DSA:1.10.357.10 48 183 3.9E-40 T 12-10-2018 TSC_c12140 7cfb923d43ed20f14df07f21a62145a1 195 Gene3D G3DSA:1.10.10.60 1 47 4.8E-15 T 12-10-2018 TSC_c12140 7cfb923d43ed20f14df07f21a62145a1 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 7.0E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSC_c12140 7cfb923d43ed20f14df07f21a62145a1 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 7.0E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSC_c12140 7cfb923d43ed20f14df07f21a62145a1 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 5.4E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSC_c12140 7cfb923d43ed20f14df07f21a62145a1 195 SUPERFAMILY SSF48498 71 183 6.53E-25 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSC_c12140 7cfb923d43ed20f14df07f21a62145a1 195 SUPERFAMILY SSF46689 2 68 2.57E-16 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSC_c18750 0e8762fffdbc3a955caed2f025fc2e4d 322 PIRSF PIRSF004532 3 320 1.3E-136 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 TSC_c18750 0e8762fffdbc3a955caed2f025fc2e4d 322 Gene3D G3DSA:3.40.190.90 123 284 4.0E-135 T 12-10-2018 TSC_c18750 0e8762fffdbc3a955caed2f025fc2e4d 322 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 4 320 4.8E-117 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 TSC_c18750 0e8762fffdbc3a955caed2f025fc2e4d 322 Gene3D G3DSA:3.30.540.10 9 310 4.0E-135 T 12-10-2018 TSC_c18750 0e8762fffdbc3a955caed2f025fc2e4d 322 SUPERFAMILY SSF56655 2 313 4.58E-110 T 12-10-2018 TSC_c18750 0e8762fffdbc3a955caed2f025fc2e4d 322 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 5 310 1.6E-140 T 12-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 TSC_c24410 abe8f53f0ef4501d3eb8d1d9d0deda72 88 SUPERFAMILY SSF52833 1 71 7.49E-12 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TSC_c24410 abe8f53f0ef4501d3eb8d1d9d0deda72 88 Pfam PF00462 Glutaredoxin 2 50 1.7E-9 T 12-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 TSC_c24410 abe8f53f0ef4501d3eb8d1d9d0deda72 88 Gene3D G3DSA:3.40.30.10 1 84 3.2E-12 T 12-10-2018 TSC_c23610 0e38d76554e92af03e6b2b6a791d72fe 396 SUPERFAMILY SSF53850 21 389 2.27E-68 T 12-10-2018 TSC_c23610 0e38d76554e92af03e6b2b6a791d72fe 396 Gene3D G3DSA:3.40.190.10 23 353 2.9E-73 T 12-10-2018 TSC_c23610 0e38d76554e92af03e6b2b6a791d72fe 396 Gene3D G3DSA:3.40.190.10 132 389 2.9E-73 T 12-10-2018 TSC_c23610 0e38d76554e92af03e6b2b6a791d72fe 396 Pfam PF13416 Bacterial extracellular solute-binding protein 38 339 3.5E-32 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSC_c11840 5686bfecf3cb9c63e7a27fa544bc0bb9 443 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 1 422 4.0E-182 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TSC_c11840 5686bfecf3cb9c63e7a27fa544bc0bb9 443 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 1 426 88.97 T 12-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TSC_c11840 5686bfecf3cb9c63e7a27fa544bc0bb9 443 Gene3D G3DSA:3.20.20.540 46 363 1.0E-137 T 12-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TSC_c11840 5686bfecf3cb9c63e7a27fa544bc0bb9 443 Pfam PF01964 Radical SAM ThiC family 2 421 1.0E-186 T 12-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 TSC_c01070 18796a621b9f0c3d12bd257d8523ba3a 263 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 13 263 4.3E-110 T 12-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 TSC_c01070 18796a621b9f0c3d12bd257d8523ba3a 263 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c01070 18796a621b9f0c3d12bd257d8523ba3a 263 SUPERFAMILY SSF52540 13 251 3.06E-58 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c01070 18796a621b9f0c3d12bd257d8523ba3a 263 Gene3D G3DSA:3.40.50.300 13 261 4.2E-65 T 12-10-2018 TSC_c01070 18796a621b9f0c3d12bd257d8523ba3a 263 Pfam PF00005 ABC transporter 34 188 7.2E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c01070 18796a621b9f0c3d12bd257d8523ba3a 263 SMART SM00382 40 235 7.8E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c03130 5b0b4d25d90ed2d054a28e75641fbd66 183 Gene3D G3DSA:3.90.1570.10 5 182 6.0E-18 T 12-10-2018 TSC_c03130 5b0b4d25d90ed2d054a28e75641fbd66 183 Pfam PF05685 Putative restriction endonuclease 14 171 4.3E-27 T 12-10-2018 IPR008538 Domain of unknown function DUF820 TSC_c03130 5b0b4d25d90ed2d054a28e75641fbd66 183 SUPERFAMILY SSF52980 6 179 4.08E-28 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSC_c16870 b6e0c1d2634e8832756c88cc56b3aa45 210 Pfam PF01297 Zinc-uptake complex component A periplasmic 13 205 1.0E-34 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TSC_c16870 b6e0c1d2634e8832756c88cc56b3aa45 210 SUPERFAMILY SSF53807 8 199 1.81E-37 T 12-10-2018 TSC_c16870 b6e0c1d2634e8832756c88cc56b3aa45 210 Gene3D G3DSA:3.40.50.1980 10 160 4.4E-30 T 12-10-2018 TSC_c05180 6cbf9d7ceae5c8d07335bb2d41034c77 363 Pfam PF13365 Trypsin-like peptidase domain 96 237 2.4E-35 T 12-10-2018 TSC_c05180 6cbf9d7ceae5c8d07335bb2d41034c77 363 Gene3D G3DSA:2.30.42.10 285 336 1.2E-6 T 12-10-2018 TSC_c05180 6cbf9d7ceae5c8d07335bb2d41034c77 363 PRINTS PR00834 HtrA/DegQ protease family signature 169 193 2.9E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c05180 6cbf9d7ceae5c8d07335bb2d41034c77 363 PRINTS PR00834 HtrA/DegQ protease family signature 105 117 2.9E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c05180 6cbf9d7ceae5c8d07335bb2d41034c77 363 PRINTS PR00834 HtrA/DegQ protease family signature 208 225 2.9E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c05180 6cbf9d7ceae5c8d07335bb2d41034c77 363 PRINTS PR00834 HtrA/DegQ protease family signature 127 147 2.9E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c05180 6cbf9d7ceae5c8d07335bb2d41034c77 363 PRINTS PR00834 HtrA/DegQ protease family signature 230 247 2.9E-42 T 12-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 TSC_c05180 6cbf9d7ceae5c8d07335bb2d41034c77 363 Gene3D G3DSA:2.40.10.120 49 274 1.9E-70 T 12-10-2018 TSC_c05180 6cbf9d7ceae5c8d07335bb2d41034c77 363 SUPERFAMILY SSF50494 51 276 3.32E-59 T 12-10-2018 IPR009003 Peptidase S1, PA clan TSC_c10620 bd9d99d96f9601f5f341c1a7257b9a8b 161 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 26 155 1.3E-21 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSC_c00400 9297b50af1b2da42fd5293e80257d5e1 198 Pfam PF03458 UPF0126 domain 5 77 9.9E-19 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 TSC_c00400 9297b50af1b2da42fd5293e80257d5e1 198 Pfam PF03458 UPF0126 domain 90 165 2.2E-18 T 12-10-2018 IPR005115 Uncharacterised domain UPF0126 TSC_c18720 73c988ec26ab6fe96d42cf976a9bc342 259 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 250 9.3E-113 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 TSC_c18720 73c988ec26ab6fe96d42cf976a9bc342 259 Pfam PF00977 Histidine biosynthesis protein 6 233 1.4E-87 T 12-10-2018 IPR006062 Histidine biosynthesis GO:0000105 TSC_c18720 73c988ec26ab6fe96d42cf976a9bc342 259 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 250 49.422 T 12-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 TSC_c18720 73c988ec26ab6fe96d42cf976a9bc342 259 Gene3D G3DSA:3.20.20.70 1 252 1.7E-109 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c18720 73c988ec26ab6fe96d42cf976a9bc342 259 SUPERFAMILY SSF51366 3 251 3.06E-85 T 12-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 TSC_c06500 d515c5b3a61f58362157aa4d6bad92aa 153 Pfam PF03477 ATP cone domain 50 132 1.1E-14 T 12-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 TSC_c06500 d515c5b3a61f58362157aa4d6bad92aa 153 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 144 2.1E-51 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 TSC_c06500 d515c5b3a61f58362157aa4d6bad92aa 153 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 151 78.183 T 12-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 TSC_c06950 8878adf3c95459e10628e0ded2013406 765 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 38 90 2.1E-11 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06950 8878adf3c95459e10628e0ded2013406 765 Gene3D G3DSA:2.20.25.90 30 96 5.2E-28 T 12-10-2018 TSC_c06950 8878adf3c95459e10628e0ded2013406 765 SMART SM00926 37 91 1.4E-13 T 12-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c06950 8878adf3c95459e10628e0ded2013406 765 Gene3D G3DSA:2.40.40.20 605 765 3.1E-74 T 12-10-2018 TSC_c06950 8878adf3c95459e10628e0ded2013406 765 SUPERFAMILY SSF53706 38 620 5.1E-155 T 12-10-2018 TSC_c06950 8878adf3c95459e10628e0ded2013406 765 SUPERFAMILY SSF50692 582 744 9.12E-30 T 12-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily TSC_c06950 8878adf3c95459e10628e0ded2013406 765 Pfam PF01568 Molydopterin dinucleotide binding domain 620 734 4.5E-16 T 12-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 TSC_c06950 8878adf3c95459e10628e0ded2013406 765 Pfam PF00384 Molybdopterin oxidoreductase 94 525 4.8E-61 T 12-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c09270 edda3a3c25bc612becb3342888a075f0 291 Gene3D G3DSA:1.20.1510.10 1 199 1.5E-57 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TSC_c09270 edda3a3c25bc612becb3342888a075f0 291 SUPERFAMILY SSF160240 204 283 3.4E-23 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TSC_c09270 edda3a3c25bc612becb3342888a075f0 291 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 3 284 3.9E-76 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TSC_c09270 edda3a3c25bc612becb3342888a075f0 291 Pfam PF16916 Dimerisation domain of Zinc Transporter 205 283 2.9E-24 T 12-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain TSC_c09270 edda3a3c25bc612becb3342888a075f0 291 SUPERFAMILY SSF161111 2 202 2.75E-56 T 12-10-2018 IPR027469 Cation efflux transmembrane domain superfamily TSC_c09270 edda3a3c25bc612becb3342888a075f0 291 Pfam PF01545 Cation efflux family 7 200 2.0E-45 T 12-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 TSC_c09270 edda3a3c25bc612becb3342888a075f0 291 Gene3D G3DSA:3.30.70.1350 200 290 2.6E-35 T 12-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 TSC_c24590 214aed0ab0883e21b427898107e9e09c 519 Gene3D G3DSA:3.30.950.30 14 120 2.5E-10 T 12-10-2018 IPR038461 Schlafen, AAA domain superfamily TSC_c24590 214aed0ab0883e21b427898107e9e09c 519 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 295 379 9.7E-22 T 12-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain TSC_c24590 214aed0ab0883e21b427898107e9e09c 519 Gene3D G3DSA:1.10.10.10 378 473 2.2E-5 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c24590 214aed0ab0883e21b427898107e9e09c 519 Gene3D G3DSA:3.30.565.60 230 377 1.7E-43 T 12-10-2018 IPR038475 RecG, C-terminal domain superfamily TSC_c24590 214aed0ab0883e21b427898107e9e09c 519 SUPERFAMILY SSF46785 387 498 1.87E-6 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c12630 07017a5b3ccf955ba27a06f03892bec8 195 SUPERFAMILY SSF53448 2 96 2.81E-9 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c12630 07017a5b3ccf955ba27a06f03892bec8 195 Pfam PF13632 Glycosyl transferase family group 2 1 112 1.6E-11 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSC_c03040 6cc27226f52e066e338bf4ea6a4d3002 628 Pfam PF02706 Chain length determinant protein 7 98 3.4E-12 T 12-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 TSC_c02000 b691c082de10532f82c1e1ac17a73489 232 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 225 232 3.2E-5 T 12-10-2018 TSC_c02000 b691c082de10532f82c1e1ac17a73489 232 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 117 126 3.2E-5 T 12-10-2018 TSC_c02000 b691c082de10532f82c1e1ac17a73489 232 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 3.2E-5 T 12-10-2018 TSC_c02000 b691c082de10532f82c1e1ac17a73489 232 Gene3D G3DSA:3.50.50.60 1 232 2.4E-91 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c02000 b691c082de10532f82c1e1ac17a73489 232 Pfam PF01134 Glucose inhibited division protein A 70 161 2.5E-12 T 12-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 TSC_c02000 b691c082de10532f82c1e1ac17a73489 232 Pfam PF01134 Glucose inhibited division protein A 5 40 5.7E-8 T 12-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 TSC_c02000 b691c082de10532f82c1e1ac17a73489 232 SUPERFAMILY SSF51905 2 188 5.02E-26 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c24890 ba57f65df9863276288e816b2c618b71 349 Gene3D G3DSA:1.20.1250.20 1 348 6.7E-18 T 12-10-2018 TSC_c24890 ba57f65df9863276288e816b2c618b71 349 SUPERFAMILY SSF103473 3 344 3.53E-23 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c24890 ba57f65df9863276288e816b2c618b71 349 Pfam PF07690 Major Facilitator Superfamily 8 321 2.4E-13 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c11850 0244faba888dfe5520b873df8722b474 258 SUPERFAMILY SSF53613 1 257 2.34E-85 T 12-10-2018 IPR029056 Ribokinase-like TSC_c11850 0244faba888dfe5520b873df8722b474 258 Gene3D G3DSA:3.40.1190.20 1 258 8.1E-105 T 12-10-2018 IPR029056 Ribokinase-like TSC_c11850 0244faba888dfe5520b873df8722b474 258 Pfam PF08543 Phosphomethylpyrimidine kinase 11 255 2.8E-96 T 12-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 TSC_c11850 0244faba888dfe5520b873df8722b474 258 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 4 257 8.7E-103 T 12-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSC_c15500 3b4135846195102adbea418df7c08dbd 173 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 31 161 2.5E-30 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSC_c04250 655f0cce202fa99a47edb8d04d0c710d 192 SUPERFAMILY SSF53639 11 190 3.73E-41 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TSC_c04250 655f0cce202fa99a47edb8d04d0c710d 192 Gene3D G3DSA:3.40.225.10 1 192 2.3E-71 T 12-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily TSC_c04250 655f0cce202fa99a47edb8d04d0c710d 192 SMART SM01007 7 184 3.7E-42 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal TSC_c04250 655f0cce202fa99a47edb8d04d0c710d 192 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 183 1.6E-37 T 12-10-2018 IPR001303 Class II aldolase/adducin N-terminal TSC_c04200 c8e1eb66f41fd083e93bb436520500b9 143 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 137 3.1E-49 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TSC_c04200 c8e1eb66f41fd083e93bb436520500b9 143 SUPERFAMILY SSF54637 3 140 9.04E-45 T 12-10-2018 IPR029069 HotDog domain superfamily TSC_c04200 c8e1eb66f41fd083e93bb436520500b9 143 Pfam PF07977 FabA-like domain 10 129 3.3E-29 T 12-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TSC_c04200 c8e1eb66f41fd083e93bb436520500b9 143 Gene3D G3DSA:3.10.129.10 1 143 3.9E-51 T 12-10-2018 TSC_c04200 c8e1eb66f41fd083e93bb436520500b9 143 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 1 140 31.335 T 12-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 TSC_c06860 5b17d20b491d69adea39c654abee4820 314 SUPERFAMILY SSF53098 27 303 1.9E-55 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c07550 330087b61dfd9e62af02264aa59dfad8 259 SUPERFAMILY SSF161098 10 249 2.75E-59 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c07550 330087b61dfd9e62af02264aa59dfad8 259 Gene3D G3DSA:1.10.3720.10 1 259 6.1E-60 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c07550 330087b61dfd9e62af02264aa59dfad8 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 257 6.9E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c20350 634a34aeb9052028720099593ab49e17 228 Gene3D G3DSA:3.60.21.10 1 228 1.2E-97 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TSC_c20350 634a34aeb9052028720099593ab49e17 228 Pfam PF14582 Metallophosphoesterase, calcineurin superfamily 1 227 3.6E-66 T 12-10-2018 IPR029461 Metallophosphoesterase, TT1561-like TSC_c20350 634a34aeb9052028720099593ab49e17 228 SUPERFAMILY SSF56300 3 223 6.56E-42 T 12-10-2018 TSC_c19690 d2dbc9b8394e9a8f92f0a287307b63f4 339 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 242 308 3.4E-16 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSC_c19690 d2dbc9b8394e9a8f92f0a287307b63f4 339 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 241 329 1.2E-22 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSC_c19690 d2dbc9b8394e9a8f92f0a287307b63f4 339 Gene3D G3DSA:3.40.50.300 4 339 1.2E-97 T 12-10-2018 TSC_c19690 d2dbc9b8394e9a8f92f0a287307b63f4 339 SMART SM00382 35 240 4.3E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c19690 d2dbc9b8394e9a8f92f0a287307b63f4 339 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c19690 d2dbc9b8394e9a8f92f0a287307b63f4 339 SUPERFAMILY SSF52540 6 261 2.72E-69 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c19690 d2dbc9b8394e9a8f92f0a287307b63f4 339 Pfam PF00005 ABC transporter 27 190 4.7E-27 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c07590 e6fc6b83fb58fae7faf7b1b2678cd6ba 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 5.1E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c07590 e6fc6b83fb58fae7faf7b1b2678cd6ba 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 5.1E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c07590 e6fc6b83fb58fae7faf7b1b2678cd6ba 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 5.1E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c07590 e6fc6b83fb58fae7faf7b1b2678cd6ba 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 5.1E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c07590 e6fc6b83fb58fae7faf7b1b2678cd6ba 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 5.1E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c07590 e6fc6b83fb58fae7faf7b1b2678cd6ba 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 5.1E-18 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c07590 e6fc6b83fb58fae7faf7b1b2678cd6ba 244 SUPERFAMILY SSF51735 2 232 9.41E-49 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c07590 e6fc6b83fb58fae7faf7b1b2678cd6ba 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 185 0.0025 T 12-10-2018 TSC_c07590 e6fc6b83fb58fae7faf7b1b2678cd6ba 244 Pfam PF00106 short chain dehydrogenase 3 194 6.0E-33 T 12-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR TSC_c07590 e6fc6b83fb58fae7faf7b1b2678cd6ba 244 Gene3D G3DSA:3.40.50.720 1 242 8.3E-51 T 12-10-2018 TSC_c09950 aa2f3ad9dac09c5ae1f87a6563d0df41 132 Gene3D G3DSA:1.20.120.330 10 128 2.3E-42 T 12-10-2018 TSC_c09950 aa2f3ad9dac09c5ae1f87a6563d0df41 132 SUPERFAMILY SSF81593 3 125 1.41E-29 T 12-10-2018 TSC_c09950 aa2f3ad9dac09c5ae1f87a6563d0df41 132 TIGRFAM TIGR01987 HI0074: nucleotidyltransferase substrate binding protein, HI0074 family 11 125 5.6E-18 T 12-10-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 TSC_c09950 aa2f3ad9dac09c5ae1f87a6563d0df41 132 Pfam PF08780 Nucleotidyltransferase substrate binding protein like 7 127 1.9E-29 T 12-10-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 TSC_c20410 8a274710bbdb98e1f47689e69ecae2f4 277 Pfam PF01972 Serine dehydrogenase proteinase 5 273 3.9E-128 T 12-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 TSC_c20410 8a274710bbdb98e1f47689e69ecae2f4 277 Gene3D G3DSA:3.90.226.10 54 236 1.8E-24 T 12-10-2018 TSC_c20410 8a274710bbdb98e1f47689e69ecae2f4 277 SUPERFAMILY SSF52096 53 235 1.2E-27 T 12-10-2018 IPR029045 ClpP/crotonase-like domain superfamily TSC_c03110 23271e850dd5793a8b11d9b4ada23911 365 Gene3D G3DSA:1.10.260.150 49 276 4.1E-44 T 12-10-2018 TSC_c03110 23271e850dd5793a8b11d9b4ada23911 365 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 66 208 3.7E-29 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TSC_c03110 23271e850dd5793a8b11d9b4ada23911 365 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 66 207 7.7E-30 T 12-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain TSC_c22160 1ec123f1869fe8a2e43c4fab1d8716f3 118 TIGRFAM TIGR00059 L17: ribosomal protein bL17 7 118 7.2E-40 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22160 1ec123f1869fe8a2e43c4fab1d8716f3 118 SUPERFAMILY SSF64263 1 117 1.57E-44 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22160 1ec123f1869fe8a2e43c4fab1d8716f3 118 Pfam PF01196 Ribosomal protein L17 20 117 2.3E-34 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22160 1ec123f1869fe8a2e43c4fab1d8716f3 118 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 117 25.959 T 12-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c22160 1ec123f1869fe8a2e43c4fab1d8716f3 118 Gene3D G3DSA:3.90.1030.10 1 118 7.7E-50 T 12-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 TSC_c08590 7f534668b7a609ad1b6e305cb644a8ee 263 Gene3D G3DSA:3.40.50.1980 135 260 3.5E-12 T 12-10-2018 TSC_c08590 7f534668b7a609ad1b6e305cb644a8ee 263 Pfam PF01497 Periplasmic binding protein 20 209 2.4E-22 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain TSC_c08590 7f534668b7a609ad1b6e305cb644a8ee 263 SUPERFAMILY SSF53807 7 257 8.63E-41 T 12-10-2018 TSC_c08590 7f534668b7a609ad1b6e305cb644a8ee 263 Gene3D G3DSA:3.40.50.1980 11 134 2.9E-26 T 12-10-2018 TSC_c19300 0597e9aab625515f8bd8da1207aa3fb5 206 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 5 175 1.2E-39 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 TSC_c19300 0597e9aab625515f8bd8da1207aa3fb5 206 SUPERFAMILY SSF50715 1 181 4.71E-50 T 12-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSC_c19300 0597e9aab625515f8bd8da1207aa3fb5 206 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 95 177 2.3E-28 T 12-10-2018 IPR020057 Ribosomal protein L25, beta domain TSC_c19300 0597e9aab625515f8bd8da1207aa3fb5 206 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 17 88 1.0E-32 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 TSC_c19300 0597e9aab625515f8bd8da1207aa3fb5 206 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 3 178 23.891 T 12-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 TSC_c19300 0597e9aab625515f8bd8da1207aa3fb5 206 Gene3D G3DSA:2.170.120.20 92 185 2.6E-34 T 12-10-2018 IPR037121 Ribosomal protein L25, C-terminal TSC_c19300 0597e9aab625515f8bd8da1207aa3fb5 206 Gene3D G3DSA:2.40.240.10 1 91 3.1E-34 T 12-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 TSC_c19300 0597e9aab625515f8bd8da1207aa3fb5 206 Pfam PF01386 Ribosomal L25p family 5 88 4.4E-13 T 12-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 TSC_c00070 94d2408a771732211196295f61370b5b 476 Pfam PF01139 tRNA-splicing ligase RtcB 45 476 8.0E-156 T 12-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TSC_c00070 94d2408a771732211196295f61370b5b 476 SUPERFAMILY SSF103365 3 476 1.96E-160 T 12-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TSC_c00070 94d2408a771732211196295f61370b5b 476 ProSitePatterns PS01288 Uncharacterized protein family UPF0027 signature. 45 74 - T 12-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TSC_c00070 94d2408a771732211196295f61370b5b 476 Gene3D G3DSA:3.90.1860.10 1 476 1.9E-183 T 12-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 TSC_c16910 9490d0dfc6d1b0f0931724345a1b1bce 330 SMART SM00943 13 173 7.3E-33 T 12-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal TSC_c16910 9490d0dfc6d1b0f0931724345a1b1bce 330 SUPERFAMILY SSF56747 12 181 3.47E-28 T 12-10-2018 TSC_c16910 9490d0dfc6d1b0f0931724345a1b1bce 330 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 13 165 2.2E-28 T 12-10-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal TSC_c18230 ffcd27dc1fbf242ee1a0ebee332956a2 464 Pfam PF01523 Putative modulator of DNA gyrase 21 317 6.2E-61 T 12-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TSC_c18230 ffcd27dc1fbf242ee1a0ebee332956a2 464 PIRSF PIRSF004919 1 464 1.4E-112 T 12-10-2018 IPR025502 TldD TSC_c18230 ffcd27dc1fbf242ee1a0ebee332956a2 464 SUPERFAMILY SSF111283 4 463 9.29E-112 T 12-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TSC_c18230 ffcd27dc1fbf242ee1a0ebee332956a2 464 Gene3D G3DSA:3.30.2290.10 3 225 8.9E-24 T 12-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TSC_c08470 e7c17775d886e034d5e5f2fc58878a82 261 Pfam PF06182 ABC-2 family transporter protein 38 260 1.4E-61 T 12-10-2018 IPR010390 Protein of unknown function DUF990 TSC_c11800 080c17921005131206739ff2047e1386 206 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 4 197 8.6E-59 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSC_c11800 080c17921005131206739ff2047e1386 206 Pfam PF02581 Thiamine monophosphate synthase 5 185 3.4E-56 T 12-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSC_c11800 080c17921005131206739ff2047e1386 206 Gene3D G3DSA:3.20.20.70 2 203 1.5E-66 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c11800 080c17921005131206739ff2047e1386 206 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 3 203 25.422 T 12-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSC_c11800 080c17921005131206739ff2047e1386 206 SUPERFAMILY SSF51391 4 201 7.46E-64 T 12-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 TSC_c06410 0998de597e0aac2f935eb8901c6efec8 317 SUPERFAMILY SSF56752 16 315 8.63E-99 T 12-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 TSC_c06410 0998de597e0aac2f935eb8901c6efec8 317 Gene3D G3DSA:3.30.470.10 15 140 7.5E-45 T 12-10-2018 TSC_c06410 0998de597e0aac2f935eb8901c6efec8 317 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 19 315 5.4E-123 T 12-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 TSC_c06410 0998de597e0aac2f935eb8901c6efec8 317 Gene3D G3DSA:3.20.10.10 141 303 7.5E-53 T 12-10-2018 TSC_c06410 0998de597e0aac2f935eb8901c6efec8 317 Pfam PF01063 Amino-transferase class IV 45 275 1.3E-49 T 12-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 TSC_c09460 420c73b64e2994dc5e97a7fd0fb94dc0 201 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 8 197 24.803 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 TSC_c09460 420c73b64e2994dc5e97a7fd0fb94dc0 201 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 10 187 3.2E-36 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 TSC_c09460 420c73b64e2994dc5e97a7fd0fb94dc0 201 SUPERFAMILY SSF52540 6 192 2.43E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c09460 420c73b64e2994dc5e97a7fd0fb94dc0 201 Gene3D G3DSA:3.40.50.300 2 199 8.0E-65 T 12-10-2018 TSC_c09460 420c73b64e2994dc5e97a7fd0fb94dc0 201 Pfam PF01121 Dephospho-CoA kinase 9 181 5.2E-57 T 12-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 TSC_c18090 c565e58c1f476d5a847c06e78beafb2d 139 Gene3D G3DSA:3.60.90.10 7 133 2.9E-23 T 12-10-2018 TSC_c18090 c565e58c1f476d5a847c06e78beafb2d 139 SUPERFAMILY SSF56276 12 125 4.71E-25 T 12-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 TSC_c18090 c565e58c1f476d5a847c06e78beafb2d 139 Pfam PF02675 S-adenosylmethionine decarboxylase 16 123 1.8E-21 T 12-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 TSC_c24830 bae3a3e872049aec3b12ff8204b21d1d 273 SUPERFAMILY SSF52540 1 146 3.19E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c24830 bae3a3e872049aec3b12ff8204b21d1d 273 Gene3D G3DSA:3.40.50.300 30 147 4.6E-5 T 12-10-2018 TSC_c24830 bae3a3e872049aec3b12ff8204b21d1d 273 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 271 35.44 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 TSC_c24830 bae3a3e872049aec3b12ff8204b21d1d 273 PIRSF PIRSF005052 1 273 1.2E-92 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 TSC_c24830 bae3a3e872049aec3b12ff8204b21d1d 273 Pfam PF03668 P-loop ATPase protein family 1 272 9.2E-76 T 12-10-2018 IPR005337 RapZ-like family GO:0005524 TSC_c13620 a595dccb04f882a86eb0c6de45dfb846 331 Gene3D G3DSA:3.40.50.720 2 323 1.9E-156 T 12-10-2018 TSC_c13620 a595dccb04f882a86eb0c6de45dfb846 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 170 186 7.8E-37 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13620 a595dccb04f882a86eb0c6de45dfb846 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 106 119 7.8E-37 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13620 a595dccb04f882a86eb0c6de45dfb846 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 226 243 7.8E-37 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13620 a595dccb04f882a86eb0c6de45dfb846 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 143 161 7.8E-37 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13620 a595dccb04f882a86eb0c6de45dfb846 331 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 266 281 7.8E-37 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13620 a595dccb04f882a86eb0c6de45dfb846 331 SUPERFAMILY SSF51735 1 165 6.44E-65 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c13620 a595dccb04f882a86eb0c6de45dfb846 331 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 2 321 5.2E-132 T 12-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13620 a595dccb04f882a86eb0c6de45dfb846 331 Gene3D G3DSA:3.30.360.10 148 311 1.9E-156 T 12-10-2018 TSC_c13620 a595dccb04f882a86eb0c6de45dfb846 331 PIRSF PIRSF000149 1 330 3.5E-126 T 12-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13620 a595dccb04f882a86eb0c6de45dfb846 331 SUPERFAMILY SSF55347 149 310 5.36E-66 T 12-10-2018 TSC_c13620 a595dccb04f882a86eb0c6de45dfb846 331 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 154 309 4.5E-65 T 12-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13620 a595dccb04f882a86eb0c6de45dfb846 331 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 147 154 - T 12-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13620 a595dccb04f882a86eb0c6de45dfb846 331 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 1 99 2.5E-35 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c13620 a595dccb04f882a86eb0c6de45dfb846 331 SMART SM00846 1 149 4.5E-93 T 12-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 TSC_c20180 ff3d4ed291be56291118be03fcfd13f5 212 Hamap MF_00238 Cytidylate kinase [cmk]. 3 212 25.72 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TSC_c20180 ff3d4ed291be56291118be03fcfd13f5 212 TIGRFAM TIGR00017 cmk: cytidylate kinase 3 209 2.2E-51 T 12-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TSC_c20180 ff3d4ed291be56291118be03fcfd13f5 212 Pfam PF02224 Cytidylate kinase 5 211 2.2E-53 T 12-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 TSC_c20180 ff3d4ed291be56291118be03fcfd13f5 212 Gene3D G3DSA:3.40.50.300 1 212 4.6E-67 T 12-10-2018 TSC_c20180 ff3d4ed291be56291118be03fcfd13f5 212 SUPERFAMILY SSF52540 4 211 7.96E-33 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c10000 16e56b289162210832471896eb3bb729 180 Pfam PF00227 Proteasome subunit 4 176 5.1E-20 T 12-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 TSC_c10000 16e56b289162210832471896eb3bb729 180 SUPERFAMILY SSF56235 3 177 6.92E-52 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSC_c10000 16e56b289162210832471896eb3bb729 180 Gene3D G3DSA:3.60.20.10 1 177 3.7E-56 T 12-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal TSC_c10000 16e56b289162210832471896eb3bb729 180 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 6 176 8.4E-71 T 12-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 TSC_c10050 3ef7880e70592bf9c7f6c42f196cf8e9 258 Pfam PF14589 Polysulfide reductase 15 257 4.4E-45 T 12-10-2018 IPR032796 Polysulfide reductase TSC_c10050 3ef7880e70592bf9c7f6c42f196cf8e9 258 Gene3D G3DSA:1.20.1630.10 4 258 8.8E-22 T 12-10-2018 TSC_c23890 7e4002b207a016dcd8e83f3556425ba2 144 PRINTS PR01438 Universal stress protein signature 102 114 1.5E-20 T 12-10-2018 IPR006015 Universal stress protein A TSC_c23890 7e4002b207a016dcd8e83f3556425ba2 144 PRINTS PR01438 Universal stress protein signature 120 142 1.5E-20 T 12-10-2018 IPR006015 Universal stress protein A TSC_c23890 7e4002b207a016dcd8e83f3556425ba2 144 PRINTS PR01438 Universal stress protein signature 2 20 1.5E-20 T 12-10-2018 IPR006015 Universal stress protein A TSC_c23890 7e4002b207a016dcd8e83f3556425ba2 144 Pfam PF00582 Universal stress protein family 1 142 2.6E-34 T 12-10-2018 IPR006016 UspA TSC_c23890 7e4002b207a016dcd8e83f3556425ba2 144 Gene3D G3DSA:3.40.50.620 1 142 4.5E-40 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c23890 7e4002b207a016dcd8e83f3556425ba2 144 SUPERFAMILY SSF52402 2 142 5.86E-40 T 12-10-2018 TSC_c12820 be4dbdb4b2658f064007c00dd1086a22 301 Gene3D G3DSA:1.10.3720.10 17 299 9.6E-40 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c12820 be4dbdb4b2658f064007c00dd1086a22 301 SUPERFAMILY SSF161098 19 295 2.52E-42 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c12820 be4dbdb4b2658f064007c00dd1086a22 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 296 2.5E-10 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c20920 9d26b62626d67617c320879b3769e6a6 143 Gene3D G3DSA:1.10.8.640 16 94 4.5E-26 T 12-10-2018 IPR038297 CcmH/CycL/Ccl2/NrfF domain superfamily TSC_c20920 9d26b62626d67617c320879b3769e6a6 143 Pfam PF03918 Cytochrome C biogenesis protein 8 139 1.3E-33 T 12-10-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family TSC_c21550 f0e9eff096a999bd146dfb2f9de516bb 264 Gene3D G3DSA:3.30.540.10 5 143 2.6E-40 T 12-10-2018 TSC_c21550 f0e9eff096a999bd146dfb2f9de516bb 264 SUPERFAMILY SSF56655 9 260 2.23E-77 T 12-10-2018 TSC_c21550 f0e9eff096a999bd146dfb2f9de516bb 264 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 214 228 - T 12-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 TSC_c21550 f0e9eff096a999bd146dfb2f9de516bb 264 Gene3D G3DSA:3.40.190.80 146 263 4.3E-37 T 12-10-2018 TSC_c21550 f0e9eff096a999bd146dfb2f9de516bb 264 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 85 98 - T 12-10-2018 IPR020583 Inositol monophosphatase, metal-binding site TSC_c21550 f0e9eff096a999bd146dfb2f9de516bb 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 44 64 1.2E-49 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSC_c21550 f0e9eff096a999bd146dfb2f9de516bb 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 66 82 1.2E-49 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSC_c21550 f0e9eff096a999bd146dfb2f9de516bb 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 1.2E-49 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSC_c21550 f0e9eff096a999bd146dfb2f9de516bb 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 85 101 1.2E-49 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSC_c21550 f0e9eff096a999bd146dfb2f9de516bb 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 180 201 1.2E-49 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSC_c21550 f0e9eff096a999bd146dfb2f9de516bb 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 134 157 1.2E-49 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSC_c21550 f0e9eff096a999bd146dfb2f9de516bb 264 Pfam PF00459 Inositol monophosphatase family 23 260 1.2E-63 T 12-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 TSC_c21550 f0e9eff096a999bd146dfb2f9de516bb 264 PRINTS PR01959 SuhB family inositol monophosphatase signature 201 213 1.9E-7 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 TSC_c21550 f0e9eff096a999bd146dfb2f9de516bb 264 PRINTS PR01959 SuhB family inositol monophosphatase signature 108 127 1.9E-7 T 12-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 TSC_c13630 e00522217ec9fe58345b44ba4ab8f239 201 PIRSF PIRSF016661 10 201 6.9E-43 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TSC_c13630 e00522217ec9fe58345b44ba4ab8f239 201 Gene3D G3DSA:1.10.1760.20 13 198 1.4E-52 T 12-10-2018 TSC_c13630 e00522217ec9fe58345b44ba4ab8f239 201 Pfam PF02632 BioY family 47 196 6.0E-42 T 12-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 TSC_c08150 2874703850d236061773df22ad23c68d 42 Pfam PF01863 Protein of unknown function DUF45 1 25 2.7E-5 T 12-10-2018 IPR002725 Protein of unknown function DUF45 TSC_c02320 accc9aede3f28d2fc2a7eb07ea983e7b 570 Gene3D G3DSA:3.40.50.150 308 493 2.9E-19 T 12-10-2018 TSC_c02320 accc9aede3f28d2fc2a7eb07ea983e7b 570 SMART SM00530 12 67 1.6E-15 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSC_c02320 accc9aede3f28d2fc2a7eb07ea983e7b 570 Pfam PF13649 Methyltransferase domain 342 429 2.5E-8 T 12-10-2018 TSC_c02320 accc9aede3f28d2fc2a7eb07ea983e7b 570 SUPERFAMILY SSF47413 4 70 8.16E-17 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSC_c02320 accc9aede3f28d2fc2a7eb07ea983e7b 570 Gene3D G3DSA:1.10.260.40 5 71 1.1E-18 T 12-10-2018 TSC_c02320 accc9aede3f28d2fc2a7eb07ea983e7b 570 SUPERFAMILY SSF53335 316 556 2.68E-22 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c02320 accc9aede3f28d2fc2a7eb07ea983e7b 570 Pfam PF01381 Helix-turn-helix 13 67 3.3E-13 T 12-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 TSC_c02320 accc9aede3f28d2fc2a7eb07ea983e7b 570 Gene3D G3DSA:2.60.120.10 89 169 2.1E-7 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TSC_c09070 0e69a9db2b5087266767bbcbb4859232 141 Pfam PF01575 MaoC like domain 10 107 1.1E-18 T 12-10-2018 IPR002539 MaoC-like dehydratase domain TSC_c09070 0e69a9db2b5087266767bbcbb4859232 141 SUPERFAMILY SSF54637 3 138 3.1E-38 T 12-10-2018 IPR029069 HotDog domain superfamily TSC_c09070 0e69a9db2b5087266767bbcbb4859232 141 Gene3D G3DSA:3.10.129.10 1 136 3.7E-43 T 12-10-2018 TSC_c09560 02cd0fba227c96ee510053e7bacc2ac4 394 SUPERFAMILY SSF53822 30 385 8.75E-66 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TSC_c09560 02cd0fba227c96ee510053e7bacc2ac4 394 Gene3D G3DSA:3.40.50.2300 152 289 7.8E-79 T 12-10-2018 TSC_c09560 02cd0fba227c96ee510053e7bacc2ac4 394 Pfam PF13458 Periplasmic binding protein 30 382 1.7E-66 T 12-10-2018 IPR028081 Leucine-binding protein domain TSC_c09560 02cd0fba227c96ee510053e7bacc2ac4 394 Gene3D G3DSA:3.40.50.2300 39 356 7.8E-79 T 12-10-2018 TSC_c14850 3d8bbc6492e57df59f4440aa451af0b1 282 Gene3D G3DSA:3.40.50.720 108 266 5.3E-55 T 12-10-2018 TSC_c14850 3d8bbc6492e57df59f4440aa451af0b1 282 Gene3D G3DSA:3.30.1780.10 8 278 5.3E-55 T 12-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 TSC_c14850 3d8bbc6492e57df59f4440aa451af0b1 282 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 24 276 2.8E-28 T 12-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 TSC_c14850 3d8bbc6492e57df59f4440aa451af0b1 282 SUPERFAMILY SSF51735 5 280 3.1E-53 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c11100 e34e78d99a16656b7c641ae5c3c9c427 410 Pfam PF01566 Natural resistance-associated macrophage protein 32 379 2.7E-113 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 TSC_c11100 e34e78d99a16656b7c641ae5c3c9c427 410 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 12 376 2.6E-96 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 TSC_c11100 e34e78d99a16656b7c641ae5c3c9c427 410 PRINTS PR00447 Natural resistance-associated macrophage protein signature 119 138 1.3E-43 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 TSC_c11100 e34e78d99a16656b7c641ae5c3c9c427 410 PRINTS PR00447 Natural resistance-associated macrophage protein signature 352 371 1.3E-43 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 TSC_c11100 e34e78d99a16656b7c641ae5c3c9c427 410 PRINTS PR00447 Natural resistance-associated macrophage protein signature 91 117 1.3E-43 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 TSC_c11100 e34e78d99a16656b7c641ae5c3c9c427 410 PRINTS PR00447 Natural resistance-associated macrophage protein signature 294 313 1.3E-43 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 TSC_c11100 e34e78d99a16656b7c641ae5c3c9c427 410 PRINTS PR00447 Natural resistance-associated macrophage protein signature 144 165 1.3E-43 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 TSC_c11100 e34e78d99a16656b7c641ae5c3c9c427 410 PRINTS PR00447 Natural resistance-associated macrophage protein signature 196 219 1.3E-43 T 12-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 TSC_c08320 8fab0ac6db38d0a53229d10dfce2bd60 154 Pfam PF06695 Putative small multi-drug export protein 17 138 2.8E-34 T 12-10-2018 IPR009577 Putative small multi-drug export TSC_c25010 a7950c58b1180102692e1e15cf40492f 102 SMART SM00278 54 73 0.0059 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSC_c25010 a7950c58b1180102692e1e15cf40492f 102 SMART SM00278 80 99 2.0 T 12-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 TSC_c25010 a7950c58b1180102692e1e15cf40492f 102 Gene3D G3DSA:1.10.150.320 29 102 3.4E-31 T 12-10-2018 TSC_c25010 a7950c58b1180102692e1e15cf40492f 102 SUPERFAMILY SSF81585 34 101 8.5E-22 T 12-10-2018 TSC_c25010 a7950c58b1180102692e1e15cf40492f 102 Pfam PF12836 Helix-hairpin-helix motif 44 101 1.2E-20 T 12-10-2018 TSC_c09050 a6923ff2977e8a6f7e8f043b0d9dd624 285 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 277 2.7E-40 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSC_c09700 6683c555f0d620f78afa01bfb4494e94 195 Gene3D G3DSA:3.40.50.300 1 195 9.5E-92 T 12-10-2018 TSC_c09700 6683c555f0d620f78afa01bfb4494e94 195 Pfam PF00025 ADP-ribosylation factor family 66 187 1.5E-6 T 12-10-2018 IPR006689 Small GTPase superfamily, ARF/SAR type GO:0005525 TSC_c09700 6683c555f0d620f78afa01bfb4494e94 195 SUPERFAMILY SSF52540 10 189 3.68E-23 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c09700 6683c555f0d620f78afa01bfb4494e94 195 PRINTS PR00449 Transforming protein P21 ras signature 13 34 9.4E-6 T 12-10-2018 TSC_c09700 6683c555f0d620f78afa01bfb4494e94 195 PRINTS PR00449 Transforming protein P21 ras signature 132 145 9.4E-6 T 12-10-2018 TSC_c09700 6683c555f0d620f78afa01bfb4494e94 195 PRINTS PR00449 Transforming protein P21 ras signature 65 87 9.4E-6 T 12-10-2018 TSC_c09700 6683c555f0d620f78afa01bfb4494e94 195 PRINTS PR00449 Transforming protein P21 ras signature 166 188 9.4E-6 T 12-10-2018 TSC_c20860 6517e84b70983b3d075946b1d695bde1 236 Pfam PF14332 Domain of unknown function (DUF4388) 2 90 6.0E-10 T 12-10-2018 IPR025497 Domain of unknown function DUF4388 TSC_c20960 a340a647fbd478a7793fa47a20a7b0ea 228 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 91 111 3.7E-29 T 12-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSC_c20960 a340a647fbd478a7793fa47a20a7b0ea 228 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 112 132 3.7E-29 T 12-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSC_c20960 a340a647fbd478a7793fa47a20a7b0ea 228 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 53 73 3.7E-29 T 12-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSC_c20960 a340a647fbd478a7793fa47a20a7b0ea 228 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 147 173 3.7E-29 T 12-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSC_c20960 a340a647fbd478a7793fa47a20a7b0ea 228 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 36 53 3.7E-29 T 12-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 TSC_c20960 a340a647fbd478a7793fa47a20a7b0ea 228 Pfam PF01578 Cytochrome C assembly protein 28 175 2.9E-30 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 TSC_c01800 9cabca1b349e1685fa828d51c9f1bbc4 173 Pfam PF00466 Ribosomal protein L10 4 98 2.0E-21 T 12-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 TSC_c01800 9cabca1b349e1685fa828d51c9f1bbc4 173 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 3 143 1.0E-8 T 12-10-2018 TSC_c01800 9cabca1b349e1685fa828d51c9f1bbc4 173 Gene3D G3DSA:3.30.70.1730 1 133 2.1E-40 T 12-10-2018 TSC_c01800 9cabca1b349e1685fa828d51c9f1bbc4 173 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 2 160 21.429 T 12-10-2018 IPR022973 Ribosomal protein L10 TSC_c01800 9cabca1b349e1685fa828d51c9f1bbc4 173 SUPERFAMILY SSF160369 4 171 8.89E-46 T 12-10-2018 TSC_c09000 20832162b4e906da8013571f1cb10f5b 277 SUPERFAMILY SSF89796 10 276 9.42E-63 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily TSC_c09000 20832162b4e906da8013571f1cb10f5b 277 Pfam PF02515 CoA-transferase family III 195 276 2.8E-7 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 TSC_c09000 20832162b4e906da8013571f1cb10f5b 277 Pfam PF02515 CoA-transferase family III 10 161 2.9E-35 T 12-10-2018 IPR003673 CoA-transferase family III GO:0003824 TSC_c09000 20832162b4e906da8013571f1cb10f5b 277 Gene3D G3DSA:3.30.1540.10 194 275 7.1E-14 T 12-10-2018 TSC_c09000 20832162b4e906da8013571f1cb10f5b 277 Gene3D G3DSA:3.40.50.10540 9 193 5.5E-44 T 12-10-2018 IPR023606 CoA-transferase family III domain superfamily TSC_c07780 983d22ec0d9c44f40519985940b138f1 821 Gene3D G3DSA:2.40.160.50 453 821 1.7E-20 T 12-10-2018 TSC_c07780 983d22ec0d9c44f40519985940b138f1 821 Pfam PF08479 POTRA domain, ShlB-type 166 236 2.5E-4 T 12-10-2018 IPR013686 Polypeptide-transport-associated, ShlB-type TSC_c07780 983d22ec0d9c44f40519985940b138f1 821 Gene3D G3DSA:3.10.20.310 362 452 1.2E-9 T 12-10-2018 TSC_c07780 983d22ec0d9c44f40519985940b138f1 821 Pfam PF07244 Surface antigen variable number repeat 304 360 2.9E-11 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 TSC_c07780 983d22ec0d9c44f40519985940b138f1 821 Pfam PF07244 Surface antigen variable number repeat 84 162 6.3E-10 T 12-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 TSC_c07780 983d22ec0d9c44f40519985940b138f1 821 Gene3D G3DSA:3.10.20.310 160 237 4.9E-7 T 12-10-2018 TSC_c07780 983d22ec0d9c44f40519985940b138f1 821 Pfam PF01103 Surface antigen 477 820 1.1E-21 T 12-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 TSC_c07780 983d22ec0d9c44f40519985940b138f1 821 Gene3D G3DSA:3.10.20.310 304 361 1.2E-10 T 12-10-2018 TSC_c23630 62baeeaa68b71638b6053a625be5dfe6 258 Pfam PF01261 Xylose isomerase-like TIM barrel 42 217 2.1E-18 T 12-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain TSC_c23630 62baeeaa68b71638b6053a625be5dfe6 258 SUPERFAMILY SSF51658 4 256 2.09E-36 T 12-10-2018 IPR036237 Xylose isomerase-like superfamily TSC_c23630 62baeeaa68b71638b6053a625be5dfe6 258 Gene3D G3DSA:3.20.20.150 13 257 5.0E-43 T 12-10-2018 TSC_c05500 3dfe94eb92987d1d57313ff752be99ac 209 Pfam PF00005 ABC transporter 21 166 2.1E-30 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c05500 3dfe94eb92987d1d57313ff752be99ac 209 SMART SM00382 29 207 8.1E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c05500 3dfe94eb92987d1d57313ff752be99ac 209 Gene3D G3DSA:3.40.50.300 2 204 3.4E-58 T 12-10-2018 TSC_c05500 3dfe94eb92987d1d57313ff752be99ac 209 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c05500 3dfe94eb92987d1d57313ff752be99ac 209 SUPERFAMILY SSF52540 3 202 5.33E-57 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c12800 405fb865f321b2cdba4bda3f184ee845 341 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 69 83 3.6E-44 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c12800 405fb865f321b2cdba4bda3f184ee845 341 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 116 132 3.6E-44 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c12800 405fb865f321b2cdba4bda3f184ee845 341 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 85 98 3.6E-44 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c12800 405fb865f321b2cdba4bda3f184ee845 341 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 25 41 3.6E-44 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c12800 405fb865f321b2cdba4bda3f184ee845 341 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 157 176 3.6E-44 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c12800 405fb865f321b2cdba4bda3f184ee845 341 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 287 313 3.6E-44 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c12800 405fb865f321b2cdba4bda3f184ee845 341 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 41 62 3.6E-44 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c12800 405fb865f321b2cdba4bda3f184ee845 341 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 242 261 3.6E-44 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c12800 405fb865f321b2cdba4bda3f184ee845 341 SUPERFAMILY SSF53850 19 339 3.89E-85 T 12-10-2018 TSC_c12800 405fb865f321b2cdba4bda3f184ee845 341 Gene3D G3DSA:3.40.190.10 24 309 1.6E-110 T 12-10-2018 TSC_c12800 405fb865f321b2cdba4bda3f184ee845 341 Pfam PF13416 Bacterial extracellular solute-binding protein 35 295 1.3E-26 T 12-10-2018 IPR006059 Bacterial extracellular solute-binding protein TSC_c12800 405fb865f321b2cdba4bda3f184ee845 341 PIRSF PIRSF019574 4 341 2.0E-103 T 12-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 TSC_c12800 405fb865f321b2cdba4bda3f184ee845 341 Gene3D G3DSA:3.40.190.10 125 336 1.6E-110 T 12-10-2018 TSC_c02980 e3e2a116bfc0ab8fcdfbb6c812582455 206 Pfam PF02397 Bacterial sugar transferase 10 184 2.9E-64 T 12-10-2018 IPR003362 Bacterial sugar transferase TSC_c21730 5194781f86dd907e244783a191b7b02a 219 Gene3D G3DSA:3.40.50.1000 4 206 6.5E-39 T 12-10-2018 IPR023214 HAD superfamily TSC_c21730 5194781f86dd907e244783a191b7b02a 219 Pfam PF13419 Haloacid dehalogenase-like hydrolase 57 194 6.0E-20 T 12-10-2018 TSC_c21730 5194781f86dd907e244783a191b7b02a 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 112 125 3.2E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c21730 5194781f86dd907e244783a191b7b02a 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 158 3.2E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c21730 5194781f86dd907e244783a191b7b02a 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 160 180 3.2E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c21730 5194781f86dd907e244783a191b7b02a 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 3.2E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c21730 5194781f86dd907e244783a191b7b02a 219 SUPERFAMILY SSF56784 1 208 4.79E-40 T 12-10-2018 IPR036412 HAD-like superfamily TSC_c21730 5194781f86dd907e244783a191b7b02a 219 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 115 192 4.7E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c21730 5194781f86dd907e244783a191b7b02a 219 Gene3D G3DSA:1.10.150.720 18 94 6.5E-39 T 12-10-2018 TSC_c21730 5194781f86dd907e244783a191b7b02a 219 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 84 193 3.2E-11 T 12-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 TSC_c19850 00ab338b9c360475b4ca2d07809b27db 212 SUPERFAMILY SSF48498 82 196 1.58E-7 T 12-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily TSC_c19850 00ab338b9c360475b4ca2d07809b27db 212 Gene3D G3DSA:1.10.357.10 2 204 1.8E-70 T 12-10-2018 TSC_c19850 00ab338b9c360475b4ca2d07809b27db 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 5.3E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSC_c19850 00ab338b9c360475b4ca2d07809b27db 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 5.3E-7 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSC_c19850 00ab338b9c360475b4ca2d07809b27db 212 SUPERFAMILY SSF46689 3 85 4.14E-18 T 12-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 TSC_c19850 00ab338b9c360475b4ca2d07809b27db 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 7.0E-14 T 12-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 TSC_c10640 5b603cef539cbe9730d32dd52fdebc24 329 Gene3D G3DSA:3.40.190.10 103 214 8.7E-112 T 12-10-2018 TSC_c10640 5b603cef539cbe9730d32dd52fdebc24 329 Gene3D G3DSA:3.40.190.10 24 322 8.7E-112 T 12-10-2018 TSC_c10640 5b603cef539cbe9730d32dd52fdebc24 329 Pfam PF09084 NMT1/THI5 like 36 248 4.0E-26 T 12-10-2018 IPR015168 SsuA/THI5-like TSC_c10640 5b603cef539cbe9730d32dd52fdebc24 329 SUPERFAMILY SSF53850 19 270 3.23E-45 T 12-10-2018 TSC_c24080 7bb1727926073b2d1ac829423de6a32b 541 Gene3D G3DSA:1.10.3720.10 339 540 1.0E-27 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c24080 7bb1727926073b2d1ac829423de6a32b 541 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 382 538 9.9E-13 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c24080 7bb1727926073b2d1ac829423de6a32b 541 SUPERFAMILY SSF161098 345 530 2.35E-31 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c24080 7bb1727926073b2d1ac829423de6a32b 541 TIGRFAM TIGR01097 PhnE: phosphonate ABC transporter, permease protein PhnE 283 540 1.8E-81 T 12-10-2018 IPR005769 ABC transporter, permease PhnE/PtxC GO:0005887|GO:0015604|GO:0015716 TSC_c15010 0557d9df27ecc5778cfdf0eed57729cd 657 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 126 584 1.9E-82 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSC_c15010 0557d9df27ecc5778cfdf0eed57729cd 657 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 26 656 4.8E-201 T 12-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ TSC_c10810 a8c6a81d11494d8df1be17243522f34f 325 Pfam PF00144 Beta-lactamase 4 315 3.4E-38 T 12-10-2018 IPR001466 Beta-lactamase-related TSC_c10810 a8c6a81d11494d8df1be17243522f34f 325 Gene3D G3DSA:3.40.710.10 2 322 1.6E-54 T 12-10-2018 TSC_c10810 a8c6a81d11494d8df1be17243522f34f 325 SUPERFAMILY SSF56601 4 319 2.21E-56 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSC_c21040 31c8020851ed01621acb0ff0a5e69f09 120 SMART SM00450 18 114 7.8E-18 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c21040 31c8020851ed01621acb0ff0a5e69f09 120 Gene3D G3DSA:3.40.250.10 18 119 1.7E-26 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c21040 31c8020851ed01621acb0ff0a5e69f09 120 SUPERFAMILY SSF52821 14 118 7.07E-30 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c21040 31c8020851ed01621acb0ff0a5e69f09 120 Pfam PF00581 Rhodanese-like domain 21 109 2.0E-14 T 12-10-2018 IPR001763 Rhodanese-like domain TSC_c10080 1688fd243529e7f500b8aee0aaecc29c 49 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 48 16.303 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TSC_c10080 1688fd243529e7f500b8aee0aaecc29c 49 Pfam PF02416 mttA/Hcf106 family 2 48 9.1E-18 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 TSC_c10080 1688fd243529e7f500b8aee0aaecc29c 49 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 2 42 3.3E-19 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TSC_c14290 4927613cb61193a37103188fa0fbd7c9 376 SMART SM00382 28 211 3.9E-14 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c14290 4927613cb61193a37103188fa0fbd7c9 376 Gene3D G3DSA:2.40.50.140 285 350 2.9E-26 T 12-10-2018 TSC_c14290 4927613cb61193a37103188fa0fbd7c9 376 Gene3D G3DSA:3.40.50.300 1 238 4.2E-75 T 12-10-2018 TSC_c14290 4927613cb61193a37103188fa0fbd7c9 376 SUPERFAMILY SSF50331 236 365 8.99E-30 T 12-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal TSC_c14290 4927613cb61193a37103188fa0fbd7c9 376 Pfam PF03459 TOBE domain 301 355 1.6E-11 T 12-10-2018 IPR005116 Transport-associated OB, type 1 TSC_c14290 4927613cb61193a37103188fa0fbd7c9 376 Gene3D G3DSA:2.40.50.100 239 363 2.9E-26 T 12-10-2018 TSC_c14290 4927613cb61193a37103188fa0fbd7c9 376 Pfam PF00005 ABC transporter 20 161 2.6E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c14290 4927613cb61193a37103188fa0fbd7c9 376 SUPERFAMILY SSF52540 4 242 2.32E-88 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c14290 4927613cb61193a37103188fa0fbd7c9 376 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c17640 d2710ff416521369bcab01ec3e928cf8 383 Gene3D G3DSA:1.20.210.10 1 378 3.0E-64 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c17640 d2710ff416521369bcab01ec3e928cf8 383 SUPERFAMILY SSF81442 1 334 4.71E-37 T 12-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c17640 d2710ff416521369bcab01ec3e928cf8 383 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 1 306 1.9E-34 T 12-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c23470 485fb70e8b4d7d5421bca5de4fb6fbc5 235 SUPERFAMILY SSF53335 6 219 2.11E-47 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c23470 485fb70e8b4d7d5421bca5de4fb6fbc5 235 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 12 232 7.7E-76 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TSC_c23470 485fb70e8b4d7d5421bca5de4fb6fbc5 235 Gene3D G3DSA:3.40.50.150 18 232 1.7E-61 T 12-10-2018 TSC_c23470 485fb70e8b4d7d5421bca5de4fb6fbc5 235 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 3 233 35.961 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TSC_c23470 485fb70e8b4d7d5421bca5de4fb6fbc5 235 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 23 38 - T 12-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 TSC_c23470 485fb70e8b4d7d5421bca5de4fb6fbc5 235 Pfam PF01209 ubiE/COQ5 methyltransferase family 8 231 5.2E-63 T 12-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 TSC_c15260 0bf64db39af53cae26821f929ada66da 581 Gene3D G3DSA:3.40.710.10 209 580 1.5E-86 T 12-10-2018 TSC_c15260 0bf64db39af53cae26821f929ada66da 581 Pfam PF00905 Penicillin binding protein transpeptidase domain 250 569 1.5E-51 T 12-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 TSC_c15260 0bf64db39af53cae26821f929ada66da 581 SUPERFAMILY SSF56601 165 575 1.23E-80 T 12-10-2018 IPR012338 Beta-lactamase/transpeptidase-like TSC_c15260 0bf64db39af53cae26821f929ada66da 581 Gene3D G3DSA:3.30.1390.30 69 129 3.2E-21 T 12-10-2018 TSC_c15260 0bf64db39af53cae26821f929ada66da 581 Gene3D G3DSA:3.90.1310.10 48 208 3.2E-21 T 12-10-2018 TSC_c15260 0bf64db39af53cae26821f929ada66da 581 Pfam PF03717 Penicillin-binding Protein dimerisation domain 48 198 4.3E-18 T 12-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 TSC_c15260 0bf64db39af53cae26821f929ada66da 581 SUPERFAMILY SSF56519 41 213 3.92E-27 T 12-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 TSC_c03830 f638c2ae37718aeee7396253ddd528d5 225 Gene3D G3DSA:1.10.10.10 121 222 2.3E-36 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c03830 f638c2ae37718aeee7396253ddd528d5 225 SUPERFAMILY SSF52172 1 171 6.01E-41 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c03830 f638c2ae37718aeee7396253ddd528d5 225 SMART SM00448 1 110 2.1E-45 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c03830 f638c2ae37718aeee7396253ddd528d5 225 Gene3D G3DSA:3.40.50.2300 1 120 3.9E-38 T 12-10-2018 TSC_c03830 f638c2ae37718aeee7396253ddd528d5 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 141 217 9.2E-28 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c03830 f638c2ae37718aeee7396253ddd528d5 225 Pfam PF00072 Response regulator receiver domain 3 110 1.6E-29 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c03830 f638c2ae37718aeee7396253ddd528d5 225 SMART SM00862 141 217 4.0E-30 T 12-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 TSC_c12810 5eddec6f021529be06a3264f589eebf0 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 259 4.1E-14 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c12810 5eddec6f021529be06a3264f589eebf0 263 SUPERFAMILY SSF161098 13 253 5.1E-50 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c12810 5eddec6f021529be06a3264f589eebf0 263 Gene3D G3DSA:1.10.3720.10 3 263 2.2E-47 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c02530 57375512c9b915f92360a10a38efb90e 204 Pfam PF16357 Putative PepSY_TM-like 21 194 2.5E-32 T 12-10-2018 IPR032307 Putative PepSY TM-like protein TSC_c12940 42f176e1b0cb39f83ee30647cd0d8be8 286 PRINTS PR00690 Adhesin family signature 48 61 9.3E-14 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TSC_c12940 42f176e1b0cb39f83ee30647cd0d8be8 286 PRINTS PR00690 Adhesin family signature 61 78 9.3E-14 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TSC_c12940 42f176e1b0cb39f83ee30647cd0d8be8 286 PRINTS PR00690 Adhesin family signature 179 200 9.3E-14 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TSC_c12940 42f176e1b0cb39f83ee30647cd0d8be8 286 PRINTS PR00690 Adhesin family signature 17 35 9.3E-14 T 12-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 TSC_c12940 42f176e1b0cb39f83ee30647cd0d8be8 286 SUPERFAMILY SSF53807 10 284 2.99E-72 T 12-10-2018 TSC_c12940 42f176e1b0cb39f83ee30647cd0d8be8 286 Pfam PF01297 Zinc-uptake complex component A periplasmic 20 284 5.6E-67 T 12-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 TSC_c12940 42f176e1b0cb39f83ee30647cd0d8be8 286 Gene3D G3DSA:3.40.50.1980 184 285 1.9E-21 T 12-10-2018 TSC_c12940 42f176e1b0cb39f83ee30647cd0d8be8 286 PRINTS PR00691 Adhesin B signature 42 60 2.1E-15 T 12-10-2018 IPR006129 Adhesin B GO:0007155 TSC_c12940 42f176e1b0cb39f83ee30647cd0d8be8 286 PRINTS PR00691 Adhesin B signature 61 80 2.1E-15 T 12-10-2018 IPR006129 Adhesin B GO:0007155 TSC_c12940 42f176e1b0cb39f83ee30647cd0d8be8 286 PRINTS PR00691 Adhesin B signature 17 38 2.1E-15 T 12-10-2018 IPR006129 Adhesin B GO:0007155 TSC_c12940 42f176e1b0cb39f83ee30647cd0d8be8 286 PRINTS PR00691 Adhesin B signature 125 144 2.1E-15 T 12-10-2018 IPR006129 Adhesin B GO:0007155 TSC_c12940 42f176e1b0cb39f83ee30647cd0d8be8 286 Gene3D G3DSA:3.40.50.1980 16 181 7.3E-45 T 12-10-2018 TSC_c06390 8ce57a82c027d7bbac6cff291c5ae591 302 SUPERFAMILY SSF47240 1 298 8.31E-99 T 12-10-2018 IPR009078 Ferritin-like superfamily TSC_c06390 8ce57a82c027d7bbac6cff291c5ae591 302 Pfam PF05067 Manganese containing catalase 1 300 3.5E-79 T 12-10-2018 IPR007760 Manganese catalase TSC_c06390 8ce57a82c027d7bbac6cff291c5ae591 302 Gene3D G3DSA:1.20.1260.130 2 302 6.4E-125 T 12-10-2018 TSC_c06600 0311787dd7f6ee8aba11f9f24032ac55 130 SUPERFAMILY SSF159888 25 77 2.09E-10 T 12-10-2018 TSC_c03690 ac45fc5006e4b3978613d39fa10df9cc 236 Pfam PF00561 alpha/beta hydrolase fold 45 221 9.5E-14 T 12-10-2018 IPR000073 Alpha/beta hydrolase fold-1 TSC_c03690 ac45fc5006e4b3978613d39fa10df9cc 236 Gene3D G3DSA:3.40.50.1820 2 235 6.6E-53 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c03690 ac45fc5006e4b3978613d39fa10df9cc 236 SUPERFAMILY SSF53474 4 233 1.49E-47 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c01860 b0ec595a1126341b61ffce25c3145ed0 68 Gene3D G3DSA:3.30.920.30 1 68 5.0E-31 T 12-10-2018 IPR038570 HicA superfamily TSC_c01860 b0ec595a1126341b61ffce25c3145ed0 68 SUPERFAMILY SSF54786 4 68 3.84E-18 T 12-10-2018 TSC_c01860 b0ec595a1126341b61ffce25c3145ed0 68 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 6 60 1.1E-16 T 12-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 TSC_c12390 978a5dd352c12f553f88e17d53e3afe9 205 ProSitePatterns PS01007 Transposases, Mutator family, signature. 18 42 - T 12-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 TSC_c12390 978a5dd352c12f553f88e17d53e3afe9 205 Pfam PF00872 Transposase, Mutator family 1 172 2.6E-33 T 12-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 TSC_c13290 4efe1efeb4492b6c60c8b52b0b0a4148 388 SUPERFAMILY SSF103473 17 386 1.44E-37 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c13290 4efe1efeb4492b6c60c8b52b0b0a4148 388 Pfam PF07690 Major Facilitator Superfamily 219 385 1.4E-15 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c13290 4efe1efeb4492b6c60c8b52b0b0a4148 388 Gene3D G3DSA:1.20.1250.20 7 194 2.6E-9 T 12-10-2018 TSC_c13290 4efe1efeb4492b6c60c8b52b0b0a4148 388 Gene3D G3DSA:1.20.1250.20 203 386 5.0E-19 T 12-10-2018 TSC_c08650 0f7d5ac6bbc6daeaea722d2cfc6a1b5a 787 Gene3D G3DSA:1.25.40.10 16 125 2.6E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c08650 0f7d5ac6bbc6daeaea722d2cfc6a1b5a 787 SUPERFAMILY SSF51445 139 516 6.63E-14 T 12-10-2018 IPR017853 Glycoside hydrolase superfamily TSC_c08650 0f7d5ac6bbc6daeaea722d2cfc6a1b5a 787 SUPERFAMILY SSF48452 22 114 3.8E-9 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c08650 0f7d5ac6bbc6daeaea722d2cfc6a1b5a 787 Gene3D G3DSA:3.20.20.80 393 543 2.5E-5 T 12-10-2018 TSC_c17630 f1f2d623e98ce5bd1b03465403ddff74 136 Pfam PF04304 Protein of unknown function (DUF454) 8 119 3.6E-32 T 12-10-2018 IPR007401 Protein of unknown function DUF454 TSC_c17630 f1f2d623e98ce5bd1b03465403ddff74 136 PIRSF PIRSF016789 7 128 1.7E-28 T 12-10-2018 IPR007401 Protein of unknown function DUF454 TSC_c22670 d694700332921a9c94b71167321af74a 307 Pfam PF01619 Proline dehydrogenase 47 292 1.8E-28 T 12-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 TSC_c22670 d694700332921a9c94b71167321af74a 307 Gene3D G3DSA:3.20.20.530 18 307 6.2E-94 T 12-10-2018 TSC_c22670 d694700332921a9c94b71167321af74a 307 SUPERFAMILY SSF51730 38 302 3.45E-68 T 12-10-2018 IPR029041 FAD-linked oxidoreductase-like TSC_c22670 d694700332921a9c94b71167321af74a 307 PIRSF PIRSF000196 3 306 3.3E-110 T 12-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 TSC_c11140 cd0c36168831affefad64bdbab588c91 77 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 73 17.78 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TSC_c11140 cd0c36168831affefad64bdbab588c91 77 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 2 47 4.5E-18 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TSC_c11140 cd0c36168831affefad64bdbab588c91 77 Pfam PF02416 mttA/Hcf106 family 4 55 3.5E-19 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 TSC_c10650 2e441b44e51ffbb9545fa596595d7f42 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 239 1.4E-24 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c10650 2e441b44e51ffbb9545fa596595d7f42 255 Gene3D G3DSA:1.10.3720.10 52 245 1.1E-21 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c10650 2e441b44e51ffbb9545fa596595d7f42 255 SUPERFAMILY SSF161098 52 236 4.71E-28 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c19960 a544cc01f22291a498fb7831be3a1d44 307 Gene3D G3DSA:3.20.20.70 3 307 1.4E-124 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c19960 a544cc01f22291a498fb7831be3a1d44 307 PIRSF PIRSF001359 1 307 1.4E-112 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TSC_c19960 a544cc01f22291a498fb7831be3a1d44 307 Pfam PF01116 Fructose-bisphosphate aldolase class-II 7 306 1.9E-102 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TSC_c19960 a544cc01f22291a498fb7831be3a1d44 307 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 84 - T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TSC_c19960 a544cc01f22291a498fb7831be3a1d44 307 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 6 307 8.2E-117 T 12-10-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 TSC_c19960 a544cc01f22291a498fb7831be3a1d44 307 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 6 306 9.6E-103 T 12-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 TSC_c19960 a544cc01f22291a498fb7831be3a1d44 307 SUPERFAMILY SSF51569 6 307 3.08E-106 T 12-10-2018 TSC_c05400 d816e959bf4050863a32dbc00e67dd0b 86 Pfam PF07704 Rv0623-like transcription factor 1 58 1.4E-15 T 12-10-2018 IPR011660 Antitoxin VapB-like TSC_c00780 0320e232a3d5f4895d64d052021fb71a 101 Gene3D G3DSA:3.40.1620.10 7 54 3.8E-8 T 12-10-2018 TSC_c00780 0320e232a3d5f4895d64d052021fb71a 101 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 54 2.8E-11 T 12-10-2018 TSC_c00780 0320e232a3d5f4895d64d052021fb71a 101 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 9 65 5.4E-15 T 12-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM TSC_c00780 0320e232a3d5f4895d64d052021fb71a 101 SUPERFAMILY SSF143120 9 85 4.05E-12 T 12-10-2018 IPR036165 YefM-like superfamily TSC_c00660 762dbd279da6e8a3bced9b400a6be69f 167 Gene3D G3DSA:3.40.50.880 1 167 8.6E-49 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c00660 762dbd279da6e8a3bced9b400a6be69f 167 Pfam PF01965 DJ-1/PfpI family 2 162 7.9E-45 T 12-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 TSC_c00660 762dbd279da6e8a3bced9b400a6be69f 167 SUPERFAMILY SSF52317 2 165 3.21E-46 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c10220 eb35af969debdec314b8c8132acc40c1 373 Gene3D G3DSA:3.40.50.2300 18 276 1.2E-105 T 12-10-2018 TSC_c10220 eb35af969debdec314b8c8132acc40c1 373 Gene3D G3DSA:3.40.50.2300 118 359 1.2E-105 T 12-10-2018 TSC_c10220 eb35af969debdec314b8c8132acc40c1 373 SUPERFAMILY SSF53822 58 206 1.02E-6 T 12-10-2018 IPR028082 Periplasmic binding protein-like I TSC_c10220 eb35af969debdec314b8c8132acc40c1 373 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 16 279 6.4E-45 T 12-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 TSC_c00180 e7a31fa5697fb6c5c129ab848b8c69f4 159 SUPERFAMILY SSF55040 9 153 3.27E-57 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSC_c00180 e7a31fa5697fb6c5c129ab848b8c69f4 159 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 7 150 2.8E-58 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSC_c00180 e7a31fa5697fb6c5c129ab848b8c69f4 159 Gene3D G3DSA:3.30.70.640 1 156 1.9E-68 T 12-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSC_c00180 e7a31fa5697fb6c5c129ab848b8c69f4 159 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 1 156 35.25 T 12-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSC_c00180 e7a31fa5697fb6c5c129ab848b8c69f4 159 Pfam PF01967 MoaC family 13 148 1.5E-52 T 12-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 TSC_c02400 e0e0fb65bc1fa308d32547cf7dfa5afc 367 Gene3D G3DSA:3.40.50.970 1 367 1.5E-126 T 12-10-2018 TSC_c02400 e0e0fb65bc1fa308d32547cf7dfa5afc 367 Pfam PF00676 Dehydrogenase E1 component 43 340 3.1E-84 T 12-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 TSC_c02400 e0e0fb65bc1fa308d32547cf7dfa5afc 367 SUPERFAMILY SSF52518 31 365 2.68E-107 T 12-10-2018 IPR029061 Thiamin diphosphate-binding fold TSC_c18240 26aa266a4131c52a227903781dcbae05 436 Gene3D G3DSA:3.30.2290.10 1 208 2.1E-31 T 12-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal TSC_c18240 26aa266a4131c52a227903781dcbae05 436 Pfam PF01523 Putative modulator of DNA gyrase 20 305 6.3E-56 T 12-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 TSC_c18240 26aa266a4131c52a227903781dcbae05 436 SUPERFAMILY SSF111283 1 435 2.09E-98 T 12-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 TSC_c21560 f6299a145c248bd090f6afa010e6065c 159 Gene3D G3DSA:2.30.110.10 3 159 2.3E-39 T 12-10-2018 IPR012349 FMN-binding split barrel GO:0048037 TSC_c21560 f6299a145c248bd090f6afa010e6065c 159 SUPERFAMILY SSF50475 1 157 3.73E-39 T 12-10-2018 TSC_c21560 f6299a145c248bd090f6afa010e6065c 159 Pfam PF01613 Flavin reductase like domain 11 155 5.1E-28 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TSC_c21560 f6299a145c248bd090f6afa010e6065c 159 SMART SM00903 10 157 2.9E-33 T 12-10-2018 IPR002563 Flavin reductase like domain GO:0010181 TSC_c18070 2b513b18a6a72bf1fc95d0a1351bd9d2 163 Pfam PF03938 Outer membrane protein (OmpH-like) 12 161 5.4E-22 T 12-10-2018 IPR005632 Chaperone protein Skp GO:0051082 TSC_c18070 2b513b18a6a72bf1fc95d0a1351bd9d2 163 Gene3D G3DSA:3.30.910.20 19 162 2.9E-19 T 12-10-2018 IPR024930 Skp domain superfamily TSC_c18070 2b513b18a6a72bf1fc95d0a1351bd9d2 163 SMART SM00935 12 162 3.4E-26 T 12-10-2018 IPR005632 Chaperone protein Skp GO:0051082 TSC_c18070 2b513b18a6a72bf1fc95d0a1351bd9d2 163 SUPERFAMILY SSF111384 28 162 1.44E-21 T 12-10-2018 TSC_c20330 8e8399fb5e68ddc067698f057ecd418c 394 Pfam PF10116 Protein required for attachment to host cells 143 257 4.1E-6 T 12-10-2018 IPR019291 Host attachment protein TSC_c06730 8b530c31b386ecd87b32f5161460a3af 737 Pfam PF13148 Protein of unknown function (DUF3987) 328 657 3.0E-56 T 12-10-2018 IPR025048 Protein of unknown function DUF3987) TSC_c05950 bdc8cd57829e9fd0c0c73ce1f1ff3472 95 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 3 90 6.1E-22 T 12-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like TSC_c05950 bdc8cd57829e9fd0c0c73ce1f1ff3472 95 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 95 18.086 T 12-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 TSC_c08130 9d489a203a0007abf4a9c54ecc6e6bb1 73 Pfam PF16277 Domain of unknown function (DUF4926) 4 58 4.8E-20 T 12-10-2018 IPR032568 Protein of unknown function DUF4926 TSC_c21120 ab0d939e3bb59bd3dcb9303ef5ac0c87 113 Gene3D G3DSA:3.40.30.10 1 112 5.2E-28 T 12-10-2018 TSC_c21120 ab0d939e3bb59bd3dcb9303ef5ac0c87 113 Pfam PF13098 Thioredoxin-like domain 6 98 5.4E-13 T 12-10-2018 IPR012336 Thioredoxin-like fold TSC_c21120 ab0d939e3bb59bd3dcb9303ef5ac0c87 113 SUPERFAMILY SSF52833 2 108 2.67E-28 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TSC_c13830 f22f1d1e5c9b4c666e9f5b2e814dc68a 287 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 16 284 4.1E-76 T 12-10-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 TSC_c13830 f22f1d1e5c9b4c666e9f5b2e814dc68a 287 SUPERFAMILY SSF103378 108 238 5.1E-7 T 12-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 TSC_c13830 f22f1d1e5c9b4c666e9f5b2e814dc68a 287 Pfam PF03313 Serine dehydratase alpha chain 17 268 9.7E-69 T 12-10-2018 IPR005130 Serine dehydratase-like, alpha subunit TSC_c11890 af18eb900b0a783bdd846aadb19cb01d 147 SUPERFAMILY SSF54637 1 145 2.88E-45 T 12-10-2018 IPR029069 HotDog domain superfamily TSC_c11890 af18eb900b0a783bdd846aadb19cb01d 147 Gene3D G3DSA:3.10.129.10 1 147 3.0E-55 T 12-10-2018 TSC_c11890 af18eb900b0a783bdd846aadb19cb01d 147 Pfam PF01575 MaoC like domain 8 116 3.7E-30 T 12-10-2018 IPR002539 MaoC-like dehydratase domain TSC_c14090 0f1529717e4cc5c2ebb6037d4876ca67 94 SUPERFAMILY SSF52821 2 90 2.1E-14 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c14090 0f1529717e4cc5c2ebb6037d4876ca67 94 Gene3D G3DSA:3.40.250.10 1 92 7.2E-19 T 12-10-2018 IPR036873 Rhodanese-like domain superfamily TSC_c17170 e17ed32340e624fcfa898adf0ff5d34b 240 Gene3D G3DSA:3.40.30.80 14 236 2.5E-55 T 12-10-2018 TSC_c17170 e17ed32340e624fcfa898adf0ff5d34b 240 Pfam PF13192 Thioredoxin domain 157 232 1.6E-14 T 12-10-2018 IPR012336 Thioredoxin-like fold TSC_c17170 e17ed32340e624fcfa898adf0ff5d34b 240 SUPERFAMILY SSF52833 15 136 3.41E-18 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TSC_c17170 e17ed32340e624fcfa898adf0ff5d34b 240 TIGRFAM TIGR02187 GlrX_arch: glutaredoxin-like domain protein 16 234 2.7E-87 T 12-10-2018 IPR011903 Glutaredoxin-like domain TSC_c17170 e17ed32340e624fcfa898adf0ff5d34b 240 SUPERFAMILY SSF52833 142 233 1.12E-17 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TSC_c04770 44f5ea02bd96a1f9db4ff6ba62dac461 948 Pfam PF06634 Protein of unknown function (DUF1156) 10 81 1.1E-22 T 12-10-2018 IPR009537 Domain of unknown function DUF1156 TSC_c04770 44f5ea02bd96a1f9db4ff6ba62dac461 948 SUPERFAMILY SSF53335 89 155 3.43E-9 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c04770 44f5ea02bd96a1f9db4ff6ba62dac461 948 Gene3D G3DSA:3.40.50.150 94 164 1.7E-6 T 12-10-2018 TSC_c20540 ba7d9c3dc6858eff6a6804824d192da1 251 SUPERFAMILY SSF52151 2 241 4.19E-50 T 12-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase TSC_c20540 ba7d9c3dc6858eff6a6804824d192da1 251 Pfam PF01734 Patatin-like phospholipase 4 159 9.0E-25 T 12-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 TSC_c20540 ba7d9c3dc6858eff6a6804824d192da1 251 Gene3D G3DSA:3.40.1090.10 86 204 2.0E-18 T 12-10-2018 TSC_c20540 ba7d9c3dc6858eff6a6804824d192da1 251 Gene3D G3DSA:3.40.1090.10 1 85 3.4E-26 T 12-10-2018 TSC_c04120 46b5400445b65b7e97d1fced01c23fb3 259 Gene3D G3DSA:3.30.1360.120 101 247 3.6E-12 T 12-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 TSC_c04120 46b5400445b65b7e97d1fced01c23fb3 259 SUPERFAMILY SSF103025 19 173 3.61E-24 T 12-10-2018 TSC_c04120 46b5400445b65b7e97d1fced01c23fb3 259 Gene3D G3DSA:3.30.70.1400 19 99 3.1E-12 T 12-10-2018 TSC_c04120 46b5400445b65b7e97d1fced01c23fb3 259 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 130 185 2.9E-11 T 12-10-2018 IPR017703 YgfZ/GcvT conserved site TSC_c09800 df5307fd53ed2c93af36105909fec098 109 Pfam PF03780 Asp23 family, cell envelope-related function 3 101 8.3E-18 T 12-10-2018 IPR005531 Alkaline shock protein Asp23 TSC_c15090 c981d37ed044b6486eb40ae6fcc22bce 291 SUPERFAMILY SSF47413 3 72 4.38E-6 T 12-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 TSC_c15090 c981d37ed044b6486eb40ae6fcc22bce 291 Pfam PF13413 Helix-turn-helix domain 7 68 1.1E-21 T 12-10-2018 TSC_c15090 c981d37ed044b6486eb40ae6fcc22bce 291 Pfam PF08308 PEGA domain 134 199 2.9E-17 T 12-10-2018 IPR013229 PEGA TSC_c15090 c981d37ed044b6486eb40ae6fcc22bce 291 Gene3D G3DSA:1.10.260.40 1 78 8.6E-25 T 12-10-2018 TSC_c15090 c981d37ed044b6486eb40ae6fcc22bce 291 Pfam PF13464 Domain of unknown function (DUF4115) 219 282 4.7E-12 T 12-10-2018 IPR025194 Domain of unknown function DUF4115 TSC_c03440 85db7a276061d1368b4685374338fac1 879 Pfam PF12838 4Fe-4S dicluster domain 726 823 7.9E-9 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c03440 85db7a276061d1368b4685374338fac1 879 Pfam PF12838 4Fe-4S dicluster domain 643 711 2.4E-8 T 12-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain TSC_c03440 85db7a276061d1368b4685374338fac1 879 SUPERFAMILY SSF53706 184 428 1.23E-7 T 12-10-2018 TSC_c03440 85db7a276061d1368b4685374338fac1 879 Gene3D G3DSA:3.30.70.20 721 869 4.1E-25 T 12-10-2018 TSC_c03440 85db7a276061d1368b4685374338fac1 879 Gene3D G3DSA:3.30.70.20 633 720 2.3E-16 T 12-10-2018 TSC_c03440 85db7a276061d1368b4685374338fac1 879 SUPERFAMILY SSF54862 635 869 4.6E-49 T 12-10-2018 TSC_c12000 410e6ecae56d86e210394b61b3c4b62e 314 SUPERFAMILY SSF161098 90 300 6.15E-18 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c12000 410e6ecae56d86e210394b61b3c4b62e 314 Gene3D G3DSA:1.10.3720.10 85 307 8.4E-25 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c12000 410e6ecae56d86e210394b61b3c4b62e 314 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 313 3.0E-41 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c14660 e76b4ffd067224a6dacb4352aead3452 401 Pfam PF04143 Sulphur transport 50 378 3.2E-65 T 12-10-2018 IPR007272 Sulphur transport domain TSC_c02150 d0ac84385ab63254261dd0fa7b35c4d2 380 Gene3D G3DSA:1.20.1250.20 1 189 3.8E-32 T 12-10-2018 TSC_c02150 d0ac84385ab63254261dd0fa7b35c4d2 380 Gene3D G3DSA:1.20.1250.20 195 375 3.2E-15 T 12-10-2018 TSC_c02150 d0ac84385ab63254261dd0fa7b35c4d2 380 Pfam PF07690 Major Facilitator Superfamily 10 233 3.5E-24 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c02150 d0ac84385ab63254261dd0fa7b35c4d2 380 SUPERFAMILY SSF103473 3 373 4.45E-54 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c07920 bb24ecd0bbb5493713c64782c1c7f6ef 377 SUPERFAMILY SSF56300 5 308 2.04E-48 T 12-10-2018 TSC_c07920 bb24ecd0bbb5493713c64782c1c7f6ef 377 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 5 239 5.1E-40 T 12-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 TSC_c07920 bb24ecd0bbb5493713c64782c1c7f6ef 377 Pfam PF00149 Calcineurin-like phosphoesterase 5 94 8.2E-12 T 12-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 TSC_c07920 bb24ecd0bbb5493713c64782c1c7f6ef 377 Gene3D G3DSA:3.60.21.10 1 263 4.6E-60 T 12-10-2018 IPR029052 Metallo-dependent phosphatase-like TSC_c15780 a01f0a06d30f90b2cdef1526964c64a6 1093 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 396 412 1.5E-13 T 12-10-2018 TSC_c15780 a01f0a06d30f90b2cdef1526964c64a6 1093 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 424 438 1.5E-13 T 12-10-2018 TSC_c15780 a01f0a06d30f90b2cdef1526964c64a6 1093 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 525 537 1.5E-13 T 12-10-2018 TSC_c15780 a01f0a06d30f90b2cdef1526964c64a6 1093 Gene3D G3DSA:3.40.50.150 375 669 1.7E-41 T 12-10-2018 TSC_c15780 a01f0a06d30f90b2cdef1526964c64a6 1093 SUPERFAMILY SSF53335 276 644 1.64E-43 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c15780 a01f0a06d30f90b2cdef1526964c64a6 1093 Pfam PF02384 N-6 DNA Methylase 376 559 1.4E-15 T 12-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 TSC_c15780 a01f0a06d30f90b2cdef1526964c64a6 1093 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 528 534 - T 12-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 TSC_c03900 135001f157932e69a365c538173d4d3a 430 SUPERFAMILY SSF101960 8 428 9.81E-113 T 12-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily TSC_c03900 135001f157932e69a365c538173d4d3a 430 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 147 419 5.0E-74 T 12-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 TSC_c03900 135001f157932e69a365c538173d4d3a 430 Pfam PF01458 Uncharacterized protein family (UPF0051) 181 402 9.2E-69 T 12-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 TSC_c18690 01ee9c76c7c8f59c12d28d04cb590ad2 202 PIRSF PIRSF000705 1 201 3.7E-60 T 12-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 TSC_c18690 01ee9c76c7c8f59c12d28d04cb590ad2 202 Pfam PF01712 Deoxynucleoside kinase 3 196 9.2E-53 T 12-10-2018 IPR031314 Deoxynucleoside kinase domain TSC_c18690 01ee9c76c7c8f59c12d28d04cb590ad2 202 SUPERFAMILY SSF52540 1 194 8.75E-41 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c18690 01ee9c76c7c8f59c12d28d04cb590ad2 202 Gene3D G3DSA:3.40.50.300 1 201 7.3E-55 T 12-10-2018 TSC_c18630 ff25b37fbdb30b5a0b5a896bfe58f382 134 Pfam PF03061 Thioesterase superfamily 42 119 7.2E-16 T 12-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 TSC_c18630 ff25b37fbdb30b5a0b5a896bfe58f382 134 SUPERFAMILY SSF54637 11 129 8.59E-31 T 12-10-2018 IPR029069 HotDog domain superfamily TSC_c18630 ff25b37fbdb30b5a0b5a896bfe58f382 134 Gene3D G3DSA:3.10.129.10 4 133 1.9E-50 T 12-10-2018 TSC_c18630 ff25b37fbdb30b5a0b5a896bfe58f382 134 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 14 127 2.9E-34 T 12-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 TSC_c04880 aa44db37ebba23db0e06b7e45ec292ca 202 SMART SM00419 139 187 3.4E-9 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSC_c04880 aa44db37ebba23db0e06b7e45ec292ca 202 SUPERFAMILY SSF46785 120 196 8.24E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c04880 aa44db37ebba23db0e06b7e45ec292ca 202 Gene3D G3DSA:1.10.10.10 118 197 1.3E-22 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c04880 aa44db37ebba23db0e06b7e45ec292ca 202 Pfam PF00027 Cyclic nucleotide-binding domain 8 81 4.5E-13 T 12-10-2018 IPR000595 Cyclic nucleotide-binding domain TSC_c04880 aa44db37ebba23db0e06b7e45ec292ca 202 Pfam PF13545 Crp-like helix-turn-helix domain 122 194 4.2E-15 T 12-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 TSC_c04880 aa44db37ebba23db0e06b7e45ec292ca 202 SUPERFAMILY SSF51206 6 106 5.11E-20 T 12-10-2018 IPR018490 Cyclic nucleotide-binding-like TSC_c04880 aa44db37ebba23db0e06b7e45ec292ca 202 Gene3D G3DSA:2.60.120.10 1 117 1.3E-23 T 12-10-2018 IPR014710 RmlC-like jelly roll fold TSC_c01980 884f4830724e2dda8b59a46c915344c2 137 Gene3D G3DSA:3.40.50.720 1 136 4.2E-37 T 12-10-2018 TSC_c01980 884f4830724e2dda8b59a46c915344c2 137 SMART SM00881 10 104 1.1E-12 T 12-10-2018 IPR003781 CoA-binding GO:0048037 TSC_c01980 884f4830724e2dda8b59a46c915344c2 137 SUPERFAMILY SSF51735 2 133 6.7E-38 T 12-10-2018 IPR036291 NAD(P)-binding domain superfamily TSC_c01980 884f4830724e2dda8b59a46c915344c2 137 Pfam PF13380 CoA binding domain 14 130 2.6E-34 T 12-10-2018 IPR003781 CoA-binding GO:0048037 TSC_c02910 f9bbbf0d3cab08500d9c0ebbcdb9c11d 440 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 348 428 1.8E-7 T 12-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain TSC_c02910 f9bbbf0d3cab08500d9c0ebbcdb9c11d 440 Pfam PF01943 Polysaccharide biosynthesis protein 29 296 2.2E-39 T 12-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 TSC_c03030 fa9ed860649625c6b740a422f6c170a8 184 Pfam PF13808 DDE_Tnp_1-associated 5 86 2.5E-15 T 12-10-2018 IPR032806 H repeat-associated protein, N-terminal TSC_c01440 8458b6fa19f7e2b45d0f204947db1873 383 ProSitePatterns PS00216 Sugar transport proteins signature 1. 250 266 - T 12-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 TSC_c01440 8458b6fa19f7e2b45d0f204947db1873 383 SUPERFAMILY SSF103473 5 372 1.83E-53 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c01440 8458b6fa19f7e2b45d0f204947db1873 383 Gene3D G3DSA:1.20.1250.20 2 368 2.8E-44 T 12-10-2018 TSC_c01440 8458b6fa19f7e2b45d0f204947db1873 383 Pfam PF07690 Major Facilitator Superfamily 9 335 4.0E-38 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c03810 192f5fcc32547509ea1393c0d0c1c097 171 Gene3D G3DSA:2.60.40.3700 20 169 3.7E-38 T 12-10-2018 TSC_c17820 3b267b3c52e52e29f1d376d387f1e04a 284 Gene3D G3DSA:3.30.70.3040 48 144 1.3E-8 T 12-10-2018 TSC_c17820 3b267b3c52e52e29f1d376d387f1e04a 284 PIRSF PIRSF003097 1 283 1.1E-58 T 12-10-2018 IPR004513 Cell division protein FtsX GO:0016021 TSC_c19680 e14a8d131970026ecdcc62dd94673001 327 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 303 6.1E-17 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSC_c19680 e14a8d131970026ecdcc62dd94673001 327 SUPERFAMILY SSF52540 7 257 1.65E-78 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c19680 e14a8d131970026ecdcc62dd94673001 327 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c19680 e14a8d131970026ecdcc62dd94673001 327 SMART SM00382 43 236 1.9E-17 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c19680 e14a8d131970026ecdcc62dd94673001 327 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 322 2.3E-27 T 12-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 TSC_c19680 e14a8d131970026ecdcc62dd94673001 327 Pfam PF00005 ABC transporter 35 186 5.3E-33 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c19680 e14a8d131970026ecdcc62dd94673001 327 Gene3D G3DSA:3.40.50.300 5 326 4.8E-108 T 12-10-2018 TSC_c16650 fb3b76bb83cb503e0ab7196804d9a7aa 627 SUPERFAMILY SSF52540 237 376 8.2E-6 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c10360 76f9ac86093eb9360b85053d57d88d65 231 Gene3D G3DSA:2.50.20.10 35 229 8.8E-31 T 12-10-2018 TSC_c10360 76f9ac86093eb9360b85053d57d88d65 231 Pfam PF17131 Outer membrane lipoprotein-sorting protein 62 229 3.8E-31 T 12-10-2018 IPR033399 Putative outer membrane lipoprotein-sorting protein TSC_c20950 f64ef41b6117953853eec52b3af142a4 142 Gene3D G3DSA:2.40.50.140 24 129 3.0E-32 T 12-10-2018 TSC_c20950 f64ef41b6117953853eec52b3af142a4 142 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 1 138 24.147 T 12-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 TSC_c20950 f64ef41b6117953853eec52b3af142a4 142 Pfam PF03100 CcmE 2 124 7.4E-38 T 12-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 TSC_c20950 f64ef41b6117953853eec52b3af142a4 142 SUPERFAMILY SSF82093 24 126 9.68E-33 T 12-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 TSC_c00970 5cea2f4bca18e0d912114fafc8797e1d 224 SUPERFAMILY SSF81452 25 223 7.72E-52 T 12-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00970 5cea2f4bca18e0d912114fafc8797e1d 224 Pfam PF00510 Cytochrome c oxidase subunit III 34 223 1.0E-22 T 12-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c00970 5cea2f4bca18e0d912114fafc8797e1d 224 Gene3D G3DSA:1.20.120.80 28 224 1.0E-52 T 12-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 TSC_c24250 e433e1c306cc84595924818913ec08f9 411 Pfam PF13552 Protein of unknown function (DUF4127) 174 354 7.8E-23 T 12-10-2018 IPR025394 Protein of unknown function DUF4127 TSC_c24250 e433e1c306cc84595924818913ec08f9 411 Pfam PF13552 Protein of unknown function (DUF4127) 21 129 7.1E-12 T 12-10-2018 IPR025394 Protein of unknown function DUF4127 TSC_c10970 c4ceaed5537e51cb3e7b7686f7a723c1 139 SUPERFAMILY SSF52402 2 139 1.1E-33 T 12-10-2018 TSC_c10970 c4ceaed5537e51cb3e7b7686f7a723c1 139 PRINTS PR01438 Universal stress protein signature 117 139 3.4E-18 T 12-10-2018 IPR006015 Universal stress protein A TSC_c10970 c4ceaed5537e51cb3e7b7686f7a723c1 139 PRINTS PR01438 Universal stress protein signature 2 20 3.4E-18 T 12-10-2018 IPR006015 Universal stress protein A TSC_c10970 c4ceaed5537e51cb3e7b7686f7a723c1 139 PRINTS PR01438 Universal stress protein signature 99 111 3.4E-18 T 12-10-2018 IPR006015 Universal stress protein A TSC_c10970 c4ceaed5537e51cb3e7b7686f7a723c1 139 Pfam PF00582 Universal stress protein family 1 139 1.4E-32 T 12-10-2018 IPR006016 UspA TSC_c10970 c4ceaed5537e51cb3e7b7686f7a723c1 139 Gene3D G3DSA:3.40.50.620 1 139 1.2E-37 T 12-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold TSC_c16120 a5f42824c912c2dbb42783422a580113 156 Pfam PF04098 Rad52/22 family double-strand break repair protein 4 128 2.2E-16 T 12-10-2018 IPR007232 DNA repair protein Rad52/59/22 GO:0006281|GO:0006310 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938 TSC_c02200 de5bde04459dc81313150ecce3149cc5 450 SUPERFAMILY SSF52467 276 449 7.09E-70 T 12-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily TSC_c02200 de5bde04459dc81313150ecce3149cc5 450 PIRSF PIRSF000204 1 449 4.5E-162 T 12-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 TSC_c02200 de5bde04459dc81313150ecce3149cc5 450 Gene3D G3DSA:3.40.50.1220 266 450 8.8E-86 T 12-10-2018 TSC_c02200 de5bde04459dc81313150ecce3149cc5 450 Pfam PF02233 NAD(P) transhydrogenase beta subunit 5 445 1.2E-175 T 12-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 TSC_c10630 c2293ef23694c7a5d06652975156e955 318 Gene3D G3DSA:3.40.190.170 18 316 1.4E-99 T 12-10-2018 IPR038404 TRAP transporter solute receptor DctP superfamily TSC_c10630 c2293ef23694c7a5d06652975156e955 318 Pfam PF03480 Bacterial extracellular solute-binding protein, family 7 27 300 2.0E-42 T 12-10-2018 IPR018389 TRAP transporter solute receptor DctP/TeaA GO:0030288|GO:0055085 TSC_c22760 80a181adf88881c72a3e6d61e8f16468 130 Pfam PF02036 SCP-2 sterol transfer family 11 105 1.1E-10 T 12-10-2018 IPR003033 SCP2 sterol-binding domain TSC_c22760 80a181adf88881c72a3e6d61e8f16468 130 Gene3D G3DSA:3.30.1050.10 1 130 3.6E-42 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily TSC_c22760 80a181adf88881c72a3e6d61e8f16468 130 SUPERFAMILY SSF55718 2 129 3.53E-33 T 12-10-2018 IPR036527 SCP2 sterol-binding domain superfamily TSC_c05230 81379a408365477a022290aaad0df01d 325 SUPERFAMILY SSF53850 21 321 3.57E-55 T 12-10-2018 TSC_c05230 81379a408365477a022290aaad0df01d 325 Gene3D G3DSA:3.40.190.10 112 257 6.7E-89 T 12-10-2018 TSC_c05230 81379a408365477a022290aaad0df01d 325 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 8 321 1.7E-76 T 12-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TSC_c05230 81379a408365477a022290aaad0df01d 325 Gene3D G3DSA:3.40.190.10 24 320 6.7E-89 T 12-10-2018 TSC_c05230 81379a408365477a022290aaad0df01d 325 Pfam PF16868 NMT1-like family 24 320 9.4E-69 T 12-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family TSC_c19150 5d3604b793b2324431156250625c081d 345 Pfam PF14332 Domain of unknown function (DUF4388) 4 158 2.9E-12 T 12-10-2018 IPR025497 Domain of unknown function DUF4388 TSC_c19150 5d3604b793b2324431156250625c081d 345 SUPERFAMILY SSF52172 228 341 5.32E-5 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c19150 5d3604b793b2324431156250625c081d 345 SUPERFAMILY SSF160246 53 108 9.42E-7 T 12-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily TSC_c07600 0c9d1ab9404fe6d642c2f06c3f2fd3e2 177 SUPERFAMILY SSF52980 4 155 3.22E-19 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSC_c07600 0c9d1ab9404fe6d642c2f06c3f2fd3e2 177 Pfam PF05685 Putative restriction endonuclease 8 164 1.3E-29 T 12-10-2018 IPR008538 Domain of unknown function DUF820 TSC_c07600 0c9d1ab9404fe6d642c2f06c3f2fd3e2 177 Gene3D G3DSA:3.90.1570.10 1 177 1.4E-16 T 12-10-2018 TSC_c11620 01559158ac23f0fd9157a46bc08cae5c 58 Gene3D G3DSA:3.30.429.10 2 51 4.4E-24 T 12-10-2018 IPR014347 Tautomerase/MIF superfamily TSC_c02070 604f02a1b70dbdfdf9ff1513500b035c 358 Gene3D G3DSA:1.20.1250.20 1 185 2.6E-17 T 12-10-2018 TSC_c02070 604f02a1b70dbdfdf9ff1513500b035c 358 SUPERFAMILY SSF103473 3 353 4.84E-35 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c02070 604f02a1b70dbdfdf9ff1513500b035c 358 Gene3D G3DSA:1.20.1250.20 186 358 6.6E-14 T 12-10-2018 TSC_c02070 604f02a1b70dbdfdf9ff1513500b035c 358 Pfam PF06779 Uncharacterised MFS-type transporter YbfB 13 349 1.6E-48 T 12-10-2018 IPR010645 Uncharacterised MFS-type transporter YbfB TSC_c21470 9c8dcff2f811157962d1b24d36016e08 175 SUPERFAMILY SSF53271 8 161 2.7E-20 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TSC_c21470 9c8dcff2f811157962d1b24d36016e08 175 Gene3D G3DSA:3.40.50.2020 1 175 6.5E-43 T 12-10-2018 TSC_c16680 96d44aa88ff4a12291669a74d3a5612f 115 Gene3D G3DSA:2.10.109.10 3 103 6.5E-19 T 12-10-2018 TSC_c16680 96d44aa88ff4a12291669a74d3a5612f 115 SUPERFAMILY SSF51306 15 102 7.46E-25 T 12-10-2018 IPR036286 LexA/Signal peptidase-like superfamily TSC_c16680 96d44aa88ff4a12291669a74d3a5612f 115 Pfam PF00717 Peptidase S24-like 20 87 8.0E-14 T 12-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C TSC_c06360 1ee7ec7caf7f411a4f2e842e85889dcd 293 Gene3D G3DSA:2.160.10.10 78 251 1.2E-36 T 12-10-2018 TSC_c06360 1ee7ec7caf7f411a4f2e842e85889dcd 293 SUPERFAMILY SSF51161 107 248 8.73E-38 T 12-10-2018 IPR011004 Trimeric LpxA-like superfamily TSC_c06360 1ee7ec7caf7f411a4f2e842e85889dcd 293 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 196 230 6.5E-5 T 12-10-2018 IPR001451 Hexapeptide repeat TSC_c13310 de7a549264075c1ff63a33f9a6f34da3 298 Pfam PF04474 Protein of unknown function (DUF554) 62 291 9.8E-73 T 12-10-2018 IPR007563 Protein of unknown function DUF554 TSC_c09040 f4fbd8171b583ebe649703d4737370a1 301 Pfam PF02653 Branched-chain amino acid transport system / permease component 35 284 2.6E-25 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSC_c24980 fe3d86495125bacde2d52f59b66c869b 216 SUPERFAMILY SSF51695 2 215 4.4E-51 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TSC_c24980 fe3d86495125bacde2d52f59b66c869b 216 Gene3D G3DSA:3.20.20.190 1 216 2.5E-56 T 12-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 TSC_c24980 fe3d86495125bacde2d52f59b66c869b 216 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 61 5.2E-17 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 TSC_c24980 fe3d86495125bacde2d52f59b66c869b 216 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 76 213 3.1E-9 T 12-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 TSC_c09810 36bd94521a89ba288a498b84dbdeb29b 151 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 1 140 16.796 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 TSC_c09810 36bd94521a89ba288a498b84dbdeb29b 151 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 3 138 1.5E-31 T 12-10-2018 IPR011605 NusB antitermination factor GO:0006353 TSC_c09810 36bd94521a89ba288a498b84dbdeb29b 151 Gene3D G3DSA:1.10.940.10 1 149 9.2E-36 T 12-10-2018 IPR035926 NusB-like superfamily TSC_c09810 36bd94521a89ba288a498b84dbdeb29b 151 SUPERFAMILY SSF48013 3 139 5.36E-30 T 12-10-2018 IPR035926 NusB-like superfamily TSC_c09810 36bd94521a89ba288a498b84dbdeb29b 151 Pfam PF01029 NusB family 3 137 1.7E-31 T 12-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 TSC_c01640 086e83054db4d80f17ca643e1be97687 266 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 2 238 8.8E-55 T 12-10-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 TSC_c01640 086e83054db4d80f17ca643e1be97687 266 Pfam PF13263 PHP-associated 209 234 3.7E-5 T 12-10-2018 TSC_c01640 086e83054db4d80f17ca643e1be97687 266 Pfam PF02811 PHP domain 2 192 2.8E-7 T 12-10-2018 IPR004013 PHP domain GO:0003824 TSC_c01640 086e83054db4d80f17ca643e1be97687 266 SUPERFAMILY SSF89550 1 253 9.16E-47 T 12-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 TSC_c01640 086e83054db4d80f17ca643e1be97687 266 Gene3D G3DSA:3.20.20.140 1 266 1.0E-79 T 12-10-2018 TSC_c07750 780be9b160fdce2eea9bbd3ca078e03c 102 SUPERFAMILY SSF103007 4 89 4.58E-19 T 12-10-2018 IPR036746 TT1725-like superfamily TSC_c07750 780be9b160fdce2eea9bbd3ca078e03c 102 Gene3D G3DSA:3.30.70.1120 1 102 2.2E-34 T 12-10-2018 IPR036746 TT1725-like superfamily TSC_c07750 780be9b160fdce2eea9bbd3ca078e03c 102 Pfam PF04456 Protein of unknown function (DUF503) 12 86 2.6E-16 T 12-10-2018 IPR007546 Protein of unknown function DUF503 TSC_c24470 cf753f4ffab33f6d22c09926ab43be7f 365 Pfam PF01594 AI-2E family transporter 16 355 1.4E-66 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like TSC_c23570 160c11f3a829a00f13ed2a46e496f9c4 407 Pfam PF07690 Major Facilitator Superfamily 254 397 8.2E-12 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c23570 160c11f3a829a00f13ed2a46e496f9c4 407 Pfam PF07690 Major Facilitator Superfamily 28 245 2.5E-8 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c23570 160c11f3a829a00f13ed2a46e496f9c4 407 SUPERFAMILY SSF103473 21 399 1.31E-25 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c23570 160c11f3a829a00f13ed2a46e496f9c4 407 Gene3D G3DSA:1.20.1250.20 243 402 2.0E-12 T 12-10-2018 TSC_c23570 160c11f3a829a00f13ed2a46e496f9c4 407 Gene3D G3DSA:1.20.1250.20 21 220 3.8E-7 T 12-10-2018 TSC_c04400 42ff236ecc9f400b99d0eb66ad431c8f 253 Pfam PF06182 ABC-2 family transporter protein 41 251 5.7E-19 T 12-10-2018 IPR010390 Protein of unknown function DUF990 TSC_c09350 31fa5c7f75a0ab979c43104a32c6a84c 327 Pfam PF12127 SigmaW regulon antibacterial 13 319 3.4E-165 T 12-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity TSC_c09350 31fa5c7f75a0ab979c43104a32c6a84c 327 Hamap MF_01562 UPF0365 protein . 3 323 46.597 T 12-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity TSC_c12740 494df3a551a9d5d70cc89918a5aa92b0 133 Pfam PF12802 MarR family 27 84 6.5E-9 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSC_c12740 494df3a551a9d5d70cc89918a5aa92b0 133 Gene3D G3DSA:1.10.10.10 2 133 7.9E-30 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c12740 494df3a551a9d5d70cc89918a5aa92b0 133 SUPERFAMILY SSF46785 4 132 9.9E-27 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c12740 494df3a551a9d5d70cc89918a5aa92b0 133 SMART SM00347 22 120 2.4E-16 T 12-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 TSC_c24780 741319fd56a0b435f5ada9609cafb3f4 392 Pfam PF12698 ABC-2 family transporter protein 20 380 1.8E-22 T 12-10-2018 TSC_c13000 392f1b756a7f3d263d8e8967756d2a45 56 SUPERFAMILY SSF52172 2 53 1.42E-11 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c13000 392f1b756a7f3d263d8e8967756d2a45 56 Pfam PF00072 Response regulator receiver domain 2 47 1.2E-6 T 12-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 TSC_c13000 392f1b756a7f3d263d8e8967756d2a45 56 Gene3D G3DSA:3.40.50.12740 1 56 2.9E-11 T 12-10-2018 TSC_c14540 a83052d827d0ba8641e5aecf97fa8729 194 Pfam PF08478 POTRA domain, FtsQ-type 24 91 5.9E-10 T 12-10-2018 IPR013685 POTRA domain, FtsQ-type TSC_c17670 a84e8e73825e8653b6c29c49af3cc4ea 65 SUPERFAMILY SSF140683 1 62 1.7E-7 T 12-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily TSC_c17670 a84e8e73825e8653b6c29c49af3cc4ea 65 Pfam PF04405 Domain of Unknown function (DUF542) 8 58 5.7E-13 T 12-10-2018 IPR019903 Repair of iron centres family TSC_c17670 a84e8e73825e8653b6c29c49af3cc4ea 65 Gene3D G3DSA:1.10.3910.10 2 63 2.7E-8 T 12-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily TSC_c12600 0cd2be5327799161f443e642b248e12a 409 SUPERFAMILY SSF52540 15 199 1.16E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c12600 0cd2be5327799161f443e642b248e12a 409 Pfam PF13635 Domain of unknown function (DUF4143) 197 355 1.1E-23 T 12-10-2018 IPR025420 Domain of unknown function DUF4143 TSC_c12600 0cd2be5327799161f443e642b248e12a 409 Pfam PF13173 AAA domain 23 137 2.2E-20 T 12-10-2018 TSC_c11750 4e61b752a8371825d170a542c8a935b0 246 Pfam PF01925 Sulfite exporter TauE/SafE 3 238 1.2E-35 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TSC_c11820 4257d8813b7cd116767d2b557592b5f1 261 Gene3D G3DSA:3.20.20.70 1 241 8.9E-106 T 12-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 TSC_c11820 4257d8813b7cd116767d2b557592b5f1 261 Pfam PF05690 Thiazole biosynthesis protein ThiG 6 250 1.3E-99 T 12-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 TSC_c11820 4257d8813b7cd116767d2b557592b5f1 261 Hamap MF_00443 Thiazole synthase [thiG]. 3 256 41.382 T 12-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 TSC_c11820 4257d8813b7cd116767d2b557592b5f1 261 SUPERFAMILY SSF110399 2 240 3.92E-71 T 12-10-2018 TSC_c09450 9c5c4d787cd2cd8e3b8902702892ae8c 371 Gene3D G3DSA:3.40.830.10 100 354 2.1E-24 T 12-10-2018 TSC_c09450 9c5c4d787cd2cd8e3b8902702892ae8c 371 Pfam PF01875 Memo-like protein 104 369 1.3E-54 T 12-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 TSC_c09450 9c5c4d787cd2cd8e3b8902702892ae8c 371 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 102 349 2.4E-19 T 12-10-2018 TSC_c12660 a55f205a45d748fe74c3655636264c5b 52 SUPERFAMILY SSF53098 5 43 5.88E-5 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c12660 a55f205a45d748fe74c3655636264c5b 52 Pfam PF13683 Integrase core domain 4 33 1.4E-8 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 TSC_c12270 a55f205a45d748fe74c3655636264c5b 52 SUPERFAMILY SSF53098 5 43 5.88E-5 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c12270 a55f205a45d748fe74c3655636264c5b 52 Pfam PF13683 Integrase core domain 4 33 1.4E-8 T 12-10-2018 IPR001584 Integrase, catalytic core GO:0015074 TSC_c13700 51cca92ddb92067fce9be74532e17ccb 82 Pfam PF13453 Transcription factor zinc-finger 6 44 2.1E-20 T 12-10-2018 IPR027392 Transcription factor zinc-finger TSC_c02590 62eebc638afed978c96a088f30fd8551 340 SUPERFAMILY SSF56954 2 333 5.62E-45 T 12-10-2018 TSC_c02590 62eebc638afed978c96a088f30fd8551 340 Gene3D G3DSA:1.20.1600.10 11 227 2.4E-27 T 12-10-2018 TSC_c02590 62eebc638afed978c96a088f30fd8551 340 Gene3D G3DSA:1.20.1600.10 228 335 1.5E-15 T 12-10-2018 TSC_c02590 62eebc638afed978c96a088f30fd8551 340 Pfam PF02321 Outer membrane efflux protein 228 329 1.2E-13 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSC_c02590 62eebc638afed978c96a088f30fd8551 340 Pfam PF02321 Outer membrane efflux protein 63 164 7.1E-9 T 12-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 TSC_c10410 614ffd738a8f64204a844e99521a0870 458 Pfam PF13556 PucR C-terminal helix-turn-helix domain 396 452 6.0E-18 T 12-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain TSC_c10410 614ffd738a8f64204a844e99521a0870 458 Gene3D G3DSA:1.10.10.2840 339 455 8.7E-18 T 12-10-2018 TSC_c15180 c47eceee3e8ec05752b38e4d2fc635eb 119 Gene3D G3DSA:3.40.50.2300 7 117 1.4E-6 T 12-10-2018 TSC_c15180 c47eceee3e8ec05752b38e4d2fc635eb 119 SUPERFAMILY SSF52172 8 114 1.71E-5 T 12-10-2018 IPR011006 CheY-like superfamily TSC_c03530 dfe6b16e4e0b0a927674360be6923c90 79 SUPERFAMILY SSF54786 6 72 6.28E-18 T 12-10-2018 TSC_c03530 dfe6b16e4e0b0a927674360be6923c90 79 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 10 66 6.2E-19 T 12-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 TSC_c03530 dfe6b16e4e0b0a927674360be6923c90 79 Gene3D G3DSA:3.30.920.30 4 73 5.4E-24 T 12-10-2018 IPR038570 HicA superfamily TSC_c11970 51780ceb1796bbc1205e77c963c76b95 223 SUPERFAMILY SSF55781 94 189 2.29E-23 T 12-10-2018 TSC_c11970 51780ceb1796bbc1205e77c963c76b95 223 Pfam PF01614 Bacterial transcriptional regulator 96 189 6.7E-14 T 12-10-2018 IPR014757 Transcription regulator IclR, C-terminal TSC_c11970 51780ceb1796bbc1205e77c963c76b95 223 Gene3D G3DSA:3.30.450.40 46 217 2.8E-23 T 12-10-2018 IPR029016 GAF-like domain superfamily TSC_c22110 c3f0ab1c8e1878f33b9683136724ec11 267 Gene3D G3DSA:3.30.70.1070 123 190 5.6E-14 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 TSC_c22110 c3f0ab1c8e1878f33b9683136724ec11 267 Gene3D G3DSA:3.30.70.1070 200 266 8.3E-11 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 TSC_c22110 c3f0ab1c8e1878f33b9683136724ec11 267 Pfam PF05036 Sporulation related domain 198 261 1.6E-11 T 12-10-2018 IPR007730 Sporulation-like domain GO:0042834 TSC_c22110 c3f0ab1c8e1878f33b9683136724ec11 267 Pfam PF05036 Sporulation related domain 122 186 3.5E-18 T 12-10-2018 IPR007730 Sporulation-like domain GO:0042834 TSC_c22110 c3f0ab1c8e1878f33b9683136724ec11 267 SUPERFAMILY SSF110997 199 264 1.7E-11 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 TSC_c22110 c3f0ab1c8e1878f33b9683136724ec11 267 SUPERFAMILY SSF110997 121 186 2.88E-17 T 12-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 TSC_c18500 95a098c20fa5f1fc787b40f19dd983e7 172 Pfam PF10722 Putative bacterial sensory transduction regulator 25 141 3.2E-19 T 12-10-2018 IPR019660 Putative sensory transduction regulator YbjN TSC_c20380 37a8c13619fa55e84fe153739954267e 139 Pfam PF06146 Phosphate-starvation-inducible E 58 125 6.1E-10 T 12-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like TSC_c24170 6f5b829de5be1098f9ae9163840a58ee 256 Pfam PF12730 ABC-2 family transporter protein 4 188 7.9E-15 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TSC_c01120 806c5471d10b67b8242d1caee34141c2 118 Pfam PF01934 Protein of unknown function DUF86 13 108 1.8E-27 T 12-10-2018 IPR008201 Protein of unknown function DUF86 TSC_c12410 f3d6058d134d07690d2903678acfe3fb 115 Pfam PF01934 Protein of unknown function DUF86 11 107 2.9E-27 T 12-10-2018 IPR008201 Protein of unknown function DUF86 TSC_c07810 1de9f3e7eca4e05e0af27c7bb248adf0 150 Pfam PF05103 DivIVA protein 3 133 3.8E-35 T 12-10-2018 IPR007793 DivIVA family TSC_c07810 1de9f3e7eca4e05e0af27c7bb248adf0 150 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 34 2.2E-10 T 12-10-2018 IPR019933 DivIVA domain TSC_c22820 e14a4abf50100578a388ed6ca7666a5e 333 SUPERFAMILY SSF101898 31 263 1.94E-6 T 12-10-2018 TSC_c22080 05776a291b3ea25ce04c65af70cd3077 624 Gene3D G3DSA:2.60.40.10 412 506 5.3E-7 T 12-10-2018 IPR013783 Immunoglobulin-like fold TSC_c22080 05776a291b3ea25ce04c65af70cd3077 624 Gene3D G3DSA:2.60.40.10 316 408 5.0E-20 T 12-10-2018 IPR013783 Immunoglobulin-like fold TSC_c22080 05776a291b3ea25ce04c65af70cd3077 624 Gene3D G3DSA:2.60.40.10 221 315 8.9E-21 T 12-10-2018 IPR013783 Immunoglobulin-like fold TSC_c22080 05776a291b3ea25ce04c65af70cd3077 624 Gene3D G3DSA:2.60.40.10 130 220 1.5E-7 T 12-10-2018 IPR013783 Immunoglobulin-like fold TSC_c00700 01327e149b10d536e107ad31e4a40f81 60 Gene3D G3DSA:1.10.40.100 18 60 2.8E-28 T 12-10-2018 TSC_c04610 018788f56a2613de52fdbde96059a5f6 330 Pfam PF00348 Polyprenyl synthetase 26 274 3.5E-52 T 12-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 TSC_c04610 018788f56a2613de52fdbde96059a5f6 330 Gene3D G3DSA:1.10.600.10 1 330 5.3E-113 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TSC_c04610 018788f56a2613de52fdbde96059a5f6 330 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 76 90 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site TSC_c04610 018788f56a2613de52fdbde96059a5f6 330 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 204 216 - T 12-10-2018 IPR033749 Polyprenyl synthetase, conserved site TSC_c04610 018788f56a2613de52fdbde96059a5f6 330 SUPERFAMILY SSF48576 15 329 4.17E-64 T 12-10-2018 IPR008949 Isoprenoid synthase domain superfamily TSC_c00600 3baa492e1e7ecf6cb3c4bf4e9fee6532 231 SUPERFAMILY SSF160387 101 186 2.88E-12 T 12-10-2018 TSC_c00600 3baa492e1e7ecf6cb3c4bf4e9fee6532 231 Pfam PF05573 NosL 49 187 2.7E-12 T 12-10-2018 IPR008719 Nitrous oxide reductase accessory protein NosL TSC_c07270 01d1867d7633a55153cd1c8acbdfd96e 147 Pfam PF03350 Uncharacterized protein family, UPF0114 10 114 2.6E-23 T 12-10-2018 IPR005134 Uncharacterised protein family UPF0114 TSC_c07270 01d1867d7633a55153cd1c8acbdfd96e 147 PIRSF PIRSF026509 2 147 3.9E-24 T 12-10-2018 IPR005134 Uncharacterised protein family UPF0114 TSC_c16050 79a11c0dc1989d998e458dd1c451ddb4 156 Gene3D G3DSA:3.40.220.10 3 156 1.6E-11 T 12-10-2018 TSC_c16050 79a11c0dc1989d998e458dd1c451ddb4 156 SUPERFAMILY SSF52949 18 155 2.35E-10 T 12-10-2018 TSC_c10660 cafdc82393806ea71b805339d7395dd2 257 SUPERFAMILY SSF52540 3 227 3.87E-67 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c10660 cafdc82393806ea71b805339d7395dd2 257 Gene3D G3DSA:3.40.50.300 1 215 1.0E-65 T 12-10-2018 TSC_c10660 cafdc82393806ea71b805339d7395dd2 257 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 12-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 TSC_c10660 cafdc82393806ea71b805339d7395dd2 257 SMART SM00382 28 208 7.9E-16 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c10660 cafdc82393806ea71b805339d7395dd2 257 Pfam PF00005 ABC transporter 20 158 2.8E-29 T 12-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 TSC_c05370 0308cbf68e1c20c97995ea0b8903273e 105 Pfam PF01909 Nucleotidyltransferase domain 10 78 6.0E-11 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSC_c05370 0308cbf68e1c20c97995ea0b8903273e 105 Gene3D G3DSA:3.30.460.10 3 102 1.6E-16 T 12-10-2018 TSC_c05370 0308cbf68e1c20c97995ea0b8903273e 105 SUPERFAMILY SSF81301 6 103 2.52E-18 T 12-10-2018 TSC_c14650 8dca8d1b14ca2103b43d0f158f9e77e5 184 Pfam PF03351 DOMON domain 41 160 1.1E-18 T 12-10-2018 IPR005018 DOMON domain TSC_c14650 8dca8d1b14ca2103b43d0f158f9e77e5 184 Pfam PF09459 Ethylbenzene dehydrogenase 66 160 1.9E-10 T 12-10-2018 IPR019020 Cytochrome c-552/DMSO reductase-like, haem-binding domain GO:0020037 TSC_c24860 7c83cc5dd75b2b64a8b5fbc27d96f3df 106 Pfam PF11482 Protein of unknown function (DUF3208) 2 106 8.9E-43 T 12-10-2018 IPR021576 Protein of unknown function DUF3208 TSC_c24860 7c83cc5dd75b2b64a8b5fbc27d96f3df 106 Gene3D G3DSA:3.30.70.2290 1 106 1.1E-51 T 12-10-2018 TSC_c21350 05f977f0ef26890dad6225ec56f835f7 109 Pfam PF03259 Roadblock/LC7 domain 11 85 6.7E-9 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain TSC_c21350 05f977f0ef26890dad6225ec56f835f7 109 Gene3D G3DSA:3.30.450.30 3 109 3.6E-10 T 12-10-2018 TSC_c21350 05f977f0ef26890dad6225ec56f835f7 109 SUPERFAMILY SSF103196 10 108 2.62E-10 T 12-10-2018 TSC_c21350 05f977f0ef26890dad6225ec56f835f7 109 SMART SM00960 3 86 7.5E-5 T 12-10-2018 IPR004942 Roadblock/LAMTOR2 domain TSC_c15340 879644000da0a050db273e5d72d9ea6c 173 Pfam PF05685 Putative restriction endonuclease 9 169 2.6E-27 T 12-10-2018 IPR008538 Domain of unknown function DUF820 TSC_c15340 879644000da0a050db273e5d72d9ea6c 173 Gene3D G3DSA:3.90.1570.10 3 164 1.2E-10 T 12-10-2018 TSC_c15340 879644000da0a050db273e5d72d9ea6c 173 SUPERFAMILY SSF52980 4 171 1.88E-17 T 12-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 TSC_c19090 9b37add8f131e5ed58a947224d2fdf81 154 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 7 136 7.5E-43 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type TSC_c19090 9b37add8f131e5ed58a947224d2fdf81 154 SUPERFAMILY SSF46785 10 138 4.49E-35 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c19090 9b37add8f131e5ed58a947224d2fdf81 154 Gene3D G3DSA:1.10.10.10 4 148 4.3E-48 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c19090 9b37add8f131e5ed58a947224d2fdf81 154 Pfam PF02082 Transcriptional regulator 7 88 4.5E-26 T 12-10-2018 IPR000944 Transcription regulator Rrf2-type TSC_c19390 04910579a6a39291065b664b6fc849df 161 SUPERFAMILY SSF53098 3 142 5.94E-51 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c19390 04910579a6a39291065b664b6fc849df 161 Hamap MF_00042 Ribonuclease H [rnhA]. 1 149 35.306 T 12-10-2018 IPR022892 Ribonuclease HI GO:0004523 TSC_c19390 04910579a6a39291065b664b6fc849df 161 Gene3D G3DSA:3.30.420.10 1 154 1.1E-55 T 12-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 TSC_c19390 04910579a6a39291065b664b6fc849df 161 Pfam PF00075 RNase H 2 140 3.5E-41 T 12-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 TSC_c21170 0ca4d8a610ed9ad8c335bd7772f0f6b8 361 Pfam PF05673 Protein of unknown function (DUF815) 133 360 3.5E-61 T 12-10-2018 IPR008533 Domain of unknown function DUF815 TSC_c21170 0ca4d8a610ed9ad8c335bd7772f0f6b8 361 Gene3D G3DSA:3.40.50.300 145 280 1.2E-9 T 12-10-2018 TSC_c21170 0ca4d8a610ed9ad8c335bd7772f0f6b8 361 SUPERFAMILY SSF52540 151 355 5.89E-19 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c21170 0ca4d8a610ed9ad8c335bd7772f0f6b8 361 SMART SM00382 176 315 0.0044 T 12-10-2018 IPR003593 AAA+ ATPase domain TSC_c00450 a8b04bdc127c68d2e7407adf6c865092 90 Gene3D G3DSA:1.20.58.500 1 90 9.5E-32 T 12-10-2018 TSC_c00450 a8b04bdc127c68d2e7407adf6c865092 90 Pfam PF03745 Domain of unknown function (DUF309) 3 52 6.2E-19 T 12-10-2018 IPR005500 Protein of unknown function DUF309 TSC_c00450 a8b04bdc127c68d2e7407adf6c865092 90 SUPERFAMILY SSF140663 2 89 9.94E-26 T 12-10-2018 IPR023203 TTHA0068-like superfamily TSC_c18450 4a4ba50266d1d075c6e58315db7e695d 303 SUPERFAMILY SSF51971 7 301 4.71E-14 T 12-10-2018 TSC_c18450 4a4ba50266d1d075c6e58315db7e695d 303 Pfam PF00890 FAD binding domain 9 38 2.0E-4 T 12-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 TSC_c18450 4a4ba50266d1d075c6e58315db7e695d 303 Gene3D G3DSA:3.50.50.60 1 89 4.6E-8 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c24140 99754e7d5a1f38a991a9d1a4e66c5058 267 Gene3D G3DSA:1.10.3720.10 6 258 1.9E-48 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c24140 99754e7d5a1f38a991a9d1a4e66c5058 267 SUPERFAMILY SSF161098 7 259 2.71E-47 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c24140 99754e7d5a1f38a991a9d1a4e66c5058 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 85 257 2.3E-19 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c01670 e8389c6455f7189ae19b9d28f772bd31 196 SUPERFAMILY SSF52499 12 193 5.49E-62 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSC_c01670 e8389c6455f7189ae19b9d28f772bd31 196 Pfam PF00857 Isochorismatase family 20 190 3.1E-42 T 12-10-2018 IPR000868 Isochorismatase-like GO:0003824 TSC_c01670 e8389c6455f7189ae19b9d28f772bd31 196 Gene3D G3DSA:3.40.50.850 10 195 7.8E-61 T 12-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 TSC_c02160 2cd9ff45f446039d25d67adaf2309a3c 270 SUPERFAMILY SSF103481 176 268 6.67E-15 T 12-10-2018 TSC_c02160 2cd9ff45f446039d25d67adaf2309a3c 270 Pfam PF00892 EamA-like transporter family 2 126 2.1E-11 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSC_c02160 2cd9ff45f446039d25d67adaf2309a3c 270 Pfam PF00892 EamA-like transporter family 137 268 3.1E-20 T 12-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 TSC_c02160 2cd9ff45f446039d25d67adaf2309a3c 270 SUPERFAMILY SSF103481 33 129 5.23E-9 T 12-10-2018 TSC_c07460 8ee29809b835fdc020b200591b0d659a 128 SUPERFAMILY SSF54427 1 126 1.85E-22 T 12-10-2018 IPR032710 NTF2-like domain superfamily TSC_c07460 8ee29809b835fdc020b200591b0d659a 128 Gene3D G3DSA:3.10.450.50 1 128 7.5E-30 T 12-10-2018 TSC_c07460 8ee29809b835fdc020b200591b0d659a 128 Pfam PF08332 Calcium/calmodulin dependent protein kinase II association domain 4 128 3.9E-48 T 12-10-2018 IPR013543 Calcium/calmodulin-dependent protein kinase II, association-domain GO:0004683|GO:0005516|GO:0006468 Reactome: R-HSA-3371571|Reactome: R-HSA-399719|Reactome: R-HSA-438066|Reactome: R-HSA-442729|Reactome: R-HSA-442742|Reactome: R-HSA-442982|Reactome: R-HSA-5576892|Reactome: R-HSA-5578775|Reactome: R-HSA-5673001|Reactome: R-HSA-877300|Reactome: R-HSA-936837 TSC_c23800 57f85aef48aa0ef6e6202e074dcb90a0 110 SUPERFAMILY SSF81301 9 109 3.04E-17 T 12-10-2018 TSC_c23800 57f85aef48aa0ef6e6202e074dcb90a0 110 Gene3D G3DSA:3.30.460.10 10 99 1.6E-12 T 12-10-2018 TSC_c23800 57f85aef48aa0ef6e6202e074dcb90a0 110 Pfam PF01909 Nucleotidyltransferase domain 24 79 3.1E-9 T 12-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 TSC_c02460 1065ebd5d67698e25ed7d6d64acf46a5 126 PIRSF PIRSF004681 1 126 2.1E-37 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 TSC_c02460 1065ebd5d67698e25ed7d6d64acf46a5 126 Pfam PF01894 Uncharacterised protein family UPF0047 15 124 1.3E-32 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 TSC_c02460 1065ebd5d67698e25ed7d6d64acf46a5 126 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 6 125 1.3E-34 T 12-10-2018 IPR001602 Uncharacterised protein family UPF0047 TSC_c02460 1065ebd5d67698e25ed7d6d64acf46a5 126 Gene3D G3DSA:2.60.120.460 1 126 2.1E-48 T 12-10-2018 IPR035917 YjbQ-like superfamily TSC_c02460 1065ebd5d67698e25ed7d6d64acf46a5 126 SUPERFAMILY SSF111038 4 125 1.27E-38 T 12-10-2018 IPR035917 YjbQ-like superfamily TSC_c21690 a043e7f795246b4e896cebeba528b52b 250 Pfam PF01578 Cytochrome C assembly protein 106 238 6.2E-13 T 12-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 TSC_c17270 1a1955ac82fe1d632c14be5ebf8c3a58 173 Pfam PF13358 DDE superfamily endonuclease 3 141 3.4E-20 T 12-10-2018 IPR038717 Tc1-like transposase, DDE domain TSC_c17270 1a1955ac82fe1d632c14be5ebf8c3a58 173 Gene3D G3DSA:3.30.420.470 9 165 3.2E-7 T 12-10-2018 TSC_c13670 2434dd82c4c66790d33dcd479aa293f4 161 SMART SM00909 59 150 5.4E-5 T 12-10-2018 IPR019606 GerMN domain TSC_c13670 2434dd82c4c66790d33dcd479aa293f4 161 Pfam PF10646 Sporulation and spore germination 94 146 5.4E-8 T 12-10-2018 IPR019606 GerMN domain TSC_c22890 ed7e1a0c1c1a1c921b9fb939b61b9f11 91 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 3 47 1.9E-21 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TSC_c22890 ed7e1a0c1c1a1c921b9fb939b61b9f11 91 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 85 19.233 T 12-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 TSC_c22890 ed7e1a0c1c1a1c921b9fb939b61b9f11 91 Pfam PF02416 mttA/Hcf106 family 3 52 8.2E-22 T 12-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 TSC_c24960 6b7b130a352758b120c7a6702fd197ef 165 Gene3D G3DSA:2.20.28.160 1 54 6.0E-9 T 12-10-2018 TSC_c21300 84687ee37c1ec5462857d89cb4206fcd 401 SUPERFAMILY SSF103473 5 391 3.14E-42 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c21300 84687ee37c1ec5462857d89cb4206fcd 401 Gene3D G3DSA:1.20.1250.20 2 384 1.3E-34 T 12-10-2018 TSC_c21300 84687ee37c1ec5462857d89cb4206fcd 401 Pfam PF05977 Transmembrane secretion effector 4 391 1.9E-30 T 12-10-2018 IPR010290 Transmembrane secretion effector TSC_c20240 565f20d3039deba97ed833ac27a005a8 211 SUPERFAMILY SSF69593 10 207 1.02E-51 T 12-10-2018 TSC_c20240 565f20d3039deba97ed833ac27a005a8 211 SMART SM00563 41 153 1.1E-36 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TSC_c20240 565f20d3039deba97ed833ac27a005a8 211 Pfam PF01553 Acyltransferase 28 150 2.5E-27 T 12-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 TSC_c06820 4577831e7b132a0b2861e01d35d3b359 497 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 9 430 2.3E-98 T 12-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane TSC_c11340 0d03b5577ac1210bdcf30c5fcdc3bd67 205 Pfam PF13411 MerR HTH family regulatory protein 43 93 2.1E-5 T 12-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 TSC_c11340 0d03b5577ac1210bdcf30c5fcdc3bd67 205 Gene3D G3DSA:1.10.1660.10 39 133 5.4E-5 T 12-10-2018 TSC_c12920 9839ed75fb42b7ef47cc744200a8cf29 556 SUPERFAMILY SSF52540 222 410 1.32E-7 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c12920 9839ed75fb42b7ef47cc744200a8cf29 556 Pfam PF09818 Predicted ATPase of the ABC class 5 430 4.6E-159 T 12-10-2018 IPR019195 ABC transporter, ATPase, putative TSC_c15100 92fae3797512704642594dba83b5bd86 92 SUPERFAMILY SSF110581 9 88 1.28E-13 T 12-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TSC_c15100 92fae3797512704642594dba83b5bd86 92 Gene3D G3DSA:3.40.1790.10 1 92 1.7E-16 T 12-10-2018 IPR022830 Indigoidine synthase A-like GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TSC_c15100 92fae3797512704642594dba83b5bd86 92 Pfam PF04227 Indigoidine synthase A like protein 3 86 1.5E-15 T 12-10-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 TSC_c09860 fb64b44e3982c59abc5dbf3d51a4246c 180 Gene3D G3DSA:3.40.50.150 4 165 6.4E-17 T 12-10-2018 TSC_c09860 fb64b44e3982c59abc5dbf3d51a4246c 180 SUPERFAMILY SSF53335 5 142 8.28E-18 T 12-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase TSC_c00320 5d1adfec41cc565d184c3580cc1aceaa 212 Gene3D G3DSA:2.50.20.10 13 212 1.8E-60 T 12-10-2018 TSC_c02870 409703ba6e57af40035728f0c01c659d 479 Pfam PF04932 O-Antigen ligase 156 305 5.9E-7 T 12-10-2018 IPR007016 O-antigen ligase-related TSC_c10580 81ee6a0e4aebaebb15879967935f1e64 379 SUPERFAMILY SSF103473 5 374 1.57E-43 T 12-10-2018 IPR036259 MFS transporter superfamily TSC_c10580 81ee6a0e4aebaebb15879967935f1e64 379 PRINTS PR01035 Tetracycline resistance protein signature 316 339 3.1E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TSC_c10580 81ee6a0e4aebaebb15879967935f1e64 379 PRINTS PR01035 Tetracycline resistance protein signature 14 30 3.1E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TSC_c10580 81ee6a0e4aebaebb15879967935f1e64 379 PRINTS PR01035 Tetracycline resistance protein signature 128 150 3.1E-5 T 12-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 TSC_c10580 81ee6a0e4aebaebb15879967935f1e64 379 Gene3D G3DSA:1.20.1250.20 2 374 6.3E-41 T 12-10-2018 TSC_c10580 81ee6a0e4aebaebb15879967935f1e64 379 Pfam PF07690 Major Facilitator Superfamily 8 335 1.8E-32 T 12-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 TSC_c09940 65860b07cdc2100b2fb2e720d914cca7 407 Gene3D G3DSA:3.40.50.410 216 391 3.5E-16 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSC_c09940 65860b07cdc2100b2fb2e720d914cca7 407 Pfam PF13519 von Willebrand factor type A domain 219 317 5.3E-8 T 12-10-2018 IPR002035 von Willebrand factor, type A TSC_c09940 65860b07cdc2100b2fb2e720d914cca7 407 SUPERFAMILY SSF53300 219 386 8.75E-16 T 12-10-2018 IPR036465 von Willebrand factor A-like domain superfamily TSC_c15250 b968421405c9de15574cf0dcb2e33be5 152 Pfam PF04093 rod shape-determining protein MreD 2 118 1.4E-6 T 12-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 TSC_c05210 4be350cc9ca5a90dfd2eddb30810b530 56 SUPERFAMILY SSF50156 5 53 7.59E-12 T 12-10-2018 IPR036034 PDZ superfamily GO:0005515 TSC_c05210 4be350cc9ca5a90dfd2eddb30810b530 56 Pfam PF13180 PDZ domain 5 50 7.5E-10 T 12-10-2018 IPR001478 PDZ domain GO:0005515 TSC_c05210 4be350cc9ca5a90dfd2eddb30810b530 56 Gene3D G3DSA:2.30.42.10 3 55 1.5E-12 T 12-10-2018 TSC_c19530 ab878c2544532a4d7fdeba55e3747936 443 Gene3D G3DSA:3.60.110.10 186 423 1.5E-18 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSC_c19530 ab878c2544532a4d7fdeba55e3747936 443 Pfam PF00795 Carbon-nitrogen hydrolase 250 405 2.4E-23 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TSC_c19530 ab878c2544532a4d7fdeba55e3747936 443 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 1 424 17.906 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 TSC_c19530 ab878c2544532a4d7fdeba55e3747936 443 SUPERFAMILY SSF56317 174 418 1.31E-41 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSC_c19530 ab878c2544532a4d7fdeba55e3747936 443 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 42 387 7.8E-61 T 12-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 TSC_c05930 bae17364a80d80b02ccea4ea3c273d34 469 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 359 385 4.2E-25 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05930 bae17364a80d80b02ccea4ea3c273d34 469 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 307 326 4.2E-25 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05930 bae17364a80d80b02ccea4ea3c273d34 469 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 219 243 4.2E-25 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05930 bae17364a80d80b02ccea4ea3c273d34 469 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 148 172 4.2E-25 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05930 bae17364a80d80b02ccea4ea3c273d34 469 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 118 137 4.2E-25 T 12-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05930 bae17364a80d80b02ccea4ea3c273d34 469 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 458 3.1E-111 T 12-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c05930 bae17364a80d80b02ccea4ea3c273d34 469 Pfam PF00361 Proton-conducting membrane transporter 112 399 5.2E-44 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c00960 3a1e02fa98d7535d9a2003831e2b090a 112 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 20 91 2.3E-14 T 12-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 TSC_c11450 b3d3a65237ce8c264e1126f295e7b370 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 2.6E-27 T 12-10-2018 TSC_c11450 b3d3a65237ce8c264e1126f295e7b370 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 308 2.6E-27 T 12-10-2018 TSC_c11450 b3d3a65237ce8c264e1126f295e7b370 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 277 292 2.6E-27 T 12-10-2018 TSC_c11450 b3d3a65237ce8c264e1126f295e7b370 404 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 2.6E-27 T 12-10-2018 TSC_c11450 b3d3a65237ce8c264e1126f295e7b370 404 Gene3D G3DSA:3.30.9.10 77 384 2.3E-147 T 12-10-2018 TSC_c11450 b3d3a65237ce8c264e1126f295e7b370 404 SUPERFAMILY SSF54373 176 274 1.8E-36 T 12-10-2018 TSC_c11450 b3d3a65237ce8c264e1126f295e7b370 404 Pfam PF01494 FAD binding domain 4 339 1.8E-68 T 12-10-2018 IPR002938 FAD-binding domain GO:0071949 TSC_c11450 b3d3a65237ce8c264e1126f295e7b370 404 SUPERFAMILY SSF51905 3 386 7.47E-56 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c11450 b3d3a65237ce8c264e1126f295e7b370 404 Gene3D G3DSA:3.50.50.60 5 350 2.3E-147 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c17890 fb73cef39477200422e9322817a3a34f 161 Pfam PF00578 AhpC/TSA family 10 137 7.9E-44 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSC_c17890 fb73cef39477200422e9322817a3a34f 161 Gene3D G3DSA:3.40.30.10 8 158 2.4E-56 T 12-10-2018 TSC_c17890 fb73cef39477200422e9322817a3a34f 161 SUPERFAMILY SSF52833 8 158 3.3E-57 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TSC_c17890 fb73cef39477200422e9322817a3a34f 161 PIRSF PIRSF000239 4 161 2.6E-30 T 12-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSC_c15850 a779fb9bf71861fbc97b80d60b750e7a 146 Pfam PF17248 Family of unknown function (DUF5317) 29 135 8.2E-25 T 12-10-2018 IPR035168 Protein of unknown function DUF5317 TSC_c03280 7c43b0557d01fde46958760c0abf80a2 180 Gene3D G3DSA:3.40.630.30 23 180 1.5E-41 T 12-10-2018 TSC_c03280 7c43b0557d01fde46958760c0abf80a2 180 Pfam PF00583 Acetyltransferase (GNAT) family 76 163 8.1E-11 T 12-10-2018 IPR000182 GNAT domain TSC_c03280 7c43b0557d01fde46958760c0abf80a2 180 SUPERFAMILY SSF55729 31 168 1.26E-25 T 12-10-2018 IPR016181 Acyl-CoA N-acyltransferase TSC_c20930 d7642e92ec0870979e31b154ffbcba03 186 Gene3D G3DSA:3.40.30.10 43 186 4.0E-39 T 12-10-2018 TSC_c20930 d7642e92ec0870979e31b154ffbcba03 186 Pfam PF00578 AhpC/TSA family 45 165 2.6E-21 T 12-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 TSC_c20930 d7642e92ec0870979e31b154ffbcba03 186 SUPERFAMILY SSF52833 40 185 2.05E-38 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TSC_c18490 461c4a5a5014d0ea1c1bb283dd657ae8 421 Gene3D G3DSA:3.90.350.10 92 340 5.7E-26 T 12-10-2018 IPR014736 Transposase, Tn5-like, core TSC_c18490 461c4a5a5014d0ea1c1bb283dd657ae8 421 SUPERFAMILY SSF53098 37 411 2.05E-46 T 12-10-2018 IPR012337 Ribonuclease H-like superfamily TSC_c18490 461c4a5a5014d0ea1c1bb283dd657ae8 421 Pfam PF01609 Transposase DDE domain 194 349 1.5E-14 T 12-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 TSC_c14320 8606188198ca9afe7e3a48d1c3fc636a 276 Pfam PF04230 Polysaccharide pyruvyl transferase 8 205 1.1E-33 T 12-10-2018 IPR007345 Polysaccharide pyruvyl transferase TSC_c14320 8606188198ca9afe7e3a48d1c3fc636a 276 TIGRFAM TIGR03609 S_layer_CsaB: polysaccharide pyruvyl transferase CsaB 2 226 4.5E-64 T 12-10-2018 IPR019896 Polysaccharide pyruvyl transferase, CsaB TSC_c16350 b31d974e3960bae7099516e8c5f32cf2 115 Pfam PF04956 TrbC/VIRB2 family 17 108 2.4E-8 T 12-10-2018 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 TSC_c17210 ebbf3708243126723b2b33e8f28370a3 282 Gene3D G3DSA:3.60.110.10 8 281 4.3E-21 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSC_c17210 ebbf3708243126723b2b33e8f28370a3 282 Pfam PF00795 Carbon-nitrogen hydrolase 43 206 2.4E-7 T 12-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 TSC_c17210 ebbf3708243126723b2b33e8f28370a3 282 SUPERFAMILY SSF56317 5 271 2.62E-25 T 12-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily TSC_c17380 725509ebd99e23f3ea6816932f49a88b 141 Pfam PF03413 Peptidase propeptide and YPEB domain 60 114 3.2E-6 T 12-10-2018 IPR025711 PepSY domain TSC_c17380 725509ebd99e23f3ea6816932f49a88b 141 Gene3D G3DSA:3.10.450.40 49 116 3.7E-5 T 12-10-2018 TSC_p800050 5cba0ed0450da88ff61916d60aaff672 134 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 52 65 - T 12-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 TSC_p800050 5cba0ed0450da88ff61916d60aaff672 134 Pfam PF00294 pfkB family carbohydrate kinase 16 109 5.1E-15 T 12-10-2018 IPR011611 Carbohydrate kinase PfkB TSC_p800050 5cba0ed0450da88ff61916d60aaff672 134 SUPERFAMILY SSF53613 12 108 4.83E-20 T 12-10-2018 IPR029056 Ribokinase-like TSC_p800050 5cba0ed0450da88ff61916d60aaff672 134 Gene3D G3DSA:3.40.1190.20 2 112 9.8E-21 T 12-10-2018 IPR029056 Ribokinase-like TSC_c00430 32cd2255de18868d893ed9427e6e4fd9 106 Pfam PF04930 FUN14 family 13 103 4.5E-25 T 12-10-2018 IPR007014 FUN14 TSC_c01320 35898289fac2a9e4566dad405fbde946 142 Gene3D G3DSA:3.90.79.10 4 132 3.0E-9 T 12-10-2018 TSC_c01320 35898289fac2a9e4566dad405fbde946 142 SUPERFAMILY SSF55811 5 124 5.69E-13 T 12-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 TSC_c01320 35898289fac2a9e4566dad405fbde946 142 Pfam PF00293 NUDIX domain 7 120 4.2E-6 T 12-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 TSC_c10490 ceebaa83f16be6c65d631914fb52d0cc 325 Pfam PF02653 Branched-chain amino acid transport system / permease component 90 311 4.7E-24 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSC_c14780 1e98059825852a9013b22b80c509ef2a 284 Pfam PF01497 Periplasmic binding protein 39 253 5.2E-33 T 12-10-2018 IPR002491 ABC transporter periplasmic binding domain TSC_c14780 1e98059825852a9013b22b80c509ef2a 284 Gene3D G3DSA:3.40.50.1980 154 283 1.3E-30 T 12-10-2018 TSC_c14780 1e98059825852a9013b22b80c509ef2a 284 SUPERFAMILY SSF53807 16 282 2.86E-67 T 12-10-2018 TSC_c14780 1e98059825852a9013b22b80c509ef2a 284 Gene3D G3DSA:3.40.50.1980 21 150 2.5E-35 T 12-10-2018 TSC_c03460 b3afdf595ea225401998545265faf6ea 172 Pfam PF11821 Protein of unknown function (DUF3341) 3 166 1.6E-50 T 12-10-2018 IPR021776 Protein of unknown function DUF3341 TSC_c20130 28930f9a63315c02da1995fa05197f7d 139 Gene3D G3DSA:3.40.50.1010 7 129 5.0E-12 T 12-10-2018 TSC_c20130 28930f9a63315c02da1995fa05197f7d 139 SUPERFAMILY SSF88723 7 125 4.21E-19 T 12-10-2018 IPR029060 PIN-like domain superfamily TSC_c20130 28930f9a63315c02da1995fa05197f7d 139 Pfam PF01850 PIN domain 7 124 7.6E-13 T 12-10-2018 IPR002716 PIN domain TSC_c00390 5346a48d9e73066a3e9b77d20e2fd7b1 223 Gene3D G3DSA:1.25.40.10 9 150 3.2E-8 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c00390 5346a48d9e73066a3e9b77d20e2fd7b1 223 Gene3D G3DSA:1.25.40.10 155 221 1.8E-6 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c00390 5346a48d9e73066a3e9b77d20e2fd7b1 223 SUPERFAMILY SSF48452 58 196 6.33E-13 T 12-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 TSC_c17110 aa932df059e74231d8f74f5e55c7b0f7 182 Pfam PF02517 CAAX protease self-immunity 86 173 1.1E-15 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TSC_c17020 01d9edb0c14cdb7d039d2b990534adb0 209 Pfam PF00535 Glycosyl transferase family 2 4 137 8.5E-23 T 12-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 TSC_c17020 01d9edb0c14cdb7d039d2b990534adb0 209 SUPERFAMILY SSF53448 4 171 1.84E-32 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c17020 01d9edb0c14cdb7d039d2b990534adb0 209 Gene3D G3DSA:3.90.550.10 2 209 5.6E-35 T 12-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases TSC_c16900 90b937d4127dbb05d5bc6cfa0182ff7c 411 Gene3D G3DSA:3.40.50.300 5 268 6.4E-27 T 12-10-2018 TSC_c16900 90b937d4127dbb05d5bc6cfa0182ff7c 411 SUPERFAMILY SSF52540 18 182 1.6E-10 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c16900 90b937d4127dbb05d5bc6cfa0182ff7c 411 Pfam PF13481 AAA domain 10 177 1.1E-25 T 12-10-2018 TSC_c23270 9db57310d3fe46e4f4d449fdea7253b6 238 SUPERFAMILY SSF53474 2 234 2.0E-28 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c23270 9db57310d3fe46e4f4d449fdea7253b6 238 Gene3D G3DSA:3.40.50.1820 1 235 1.0E-58 T 12-10-2018 IPR029058 Alpha/Beta hydrolase fold TSC_c23270 9db57310d3fe46e4f4d449fdea7253b6 238 Pfam PF12146 Serine aminopeptidase, S33 20 138 9.1E-7 T 12-10-2018 IPR022742 Serine aminopeptidase, S33 TSC_c03330 e175b19eb5dad6bda2846e0e84eabd63 258 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 256 16.567 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TSC_c03330 e175b19eb5dad6bda2846e0e84eabd63 258 Pfam PF02673 Bacitracin resistance protein BacA 6 251 5.6E-68 T 12-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 TSC_c04540 8dfe84f8bdd85d20f5ef16ccb2abacb0 123 SUPERFAMILY SSF110857 1 121 9.94E-30 T 12-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily TSC_c04540 8dfe84f8bdd85d20f5ef16ccb2abacb0 123 Gene3D G3DSA:3.10.490.10 1 123 1.1E-26 T 12-10-2018 TSC_c04540 8dfe84f8bdd85d20f5ef16ccb2abacb0 123 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 4 122 5.5E-27 T 12-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like TSC_c17140 d70d594aa9d315e0ce66d0d141f617cd 458 Pfam PF04293 SpoVR like protein 3 405 3.3E-102 T 12-10-2018 IPR007390 Sporulation stage V, protein R TSC_c04380 4bc51661def0153e2632dc1ee2fa5dd6 324 SUPERFAMILY SSF101898 21 319 2.88E-17 T 12-10-2018 TSC_c04380 4bc51661def0153e2632dc1ee2fa5dd6 324 Gene3D G3DSA:2.120.10.30 3 161 8.0E-9 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TSC_c00440 eafd56737baef5a3328680d3b66fdeb4 326 Pfam PF06089 L-asparaginase II 6 317 4.1E-98 T 12-10-2018 IPR010349 L-asparaginase II TSC_c04910 8f2793407734d987eb0128e789a402ec 103 SUPERFAMILY SSF54913 4 102 5.19E-37 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TSC_c04910 8f2793407734d987eb0128e789a402ec 103 Gene3D G3DSA:3.30.70.120 1 103 7.4E-41 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TSC_c04910 8f2793407734d987eb0128e789a402ec 103 Pfam PF03091 CutA1 divalent ion tolerance protein 4 100 7.6E-37 T 12-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 TSC_c04080 6808cd259243c3e9383ace0d0c7b80e8 241 SUPERFAMILY SSF52540 20 236 5.58E-11 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c04080 6808cd259243c3e9383ace0d0c7b80e8 241 Gene3D G3DSA:3.40.50.300 19 191 5.3E-9 T 12-10-2018 TSC_c01470 1cfc0836146f405b1394daa493c018a6 115 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 4 107 7.4E-25 T 12-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV TSC_c16880 ced4c907b2846602118e6de6780a8676 69 Gene3D G3DSA:3.30.160.250 4 65 1.3E-7 T 12-10-2018 TSC_c16880 ced4c907b2846602118e6de6780a8676 69 SUPERFAMILY SSF143100 4 49 5.49E-11 T 12-10-2018 IPR035069 TTHA1013/TTHA0281-like TSC_c11130 cc36522e995de9562dd76665358d080a 334 Pfam PF16401 Domain of unknown function (DUF5009) 32 95 1.6E-7 T 12-10-2018 IPR032176 Domain of unknown function DUF5009 TSC_c02770 bcda85501b4329e8d48e40f15a01b2f3 87 Gene3D G3DSA:3.30.160.250 1 87 5.4E-39 T 12-10-2018 TSC_c02770 bcda85501b4329e8d48e40f15a01b2f3 87 SUPERFAMILY SSF143100 5 74 9.29E-20 T 12-10-2018 IPR035069 TTHA1013/TTHA0281-like TSC_c13270 8be41f02e6bb16c989ef9870d5874896 358 Pfam PF00534 Glycosyl transferases group 1 187 332 8.3E-26 T 12-10-2018 IPR001296 Glycosyl transferase, family 1 TSC_c13270 8be41f02e6bb16c989ef9870d5874896 358 SUPERFAMILY SSF53756 5 352 1.85E-56 T 12-10-2018 TSC_c13270 8be41f02e6bb16c989ef9870d5874896 358 Gene3D G3DSA:3.40.50.2000 162 338 4.2E-45 T 12-10-2018 TSC_c13270 8be41f02e6bb16c989ef9870d5874896 358 Gene3D G3DSA:3.40.50.2000 57 161 4.2E-45 T 12-10-2018 TSC_c21970 27521ff5d0b076bfabee258c0b3dc874 484 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 28 469 1.4E-83 T 12-10-2018 IPR011199 Bacillithiol biosynthesis BshC TSC_c21970 27521ff5d0b076bfabee258c0b3dc874 484 Pfam PF10079 Bacillithiol biosynthesis BshC 26 469 1.7E-75 T 12-10-2018 IPR011199 Bacillithiol biosynthesis BshC TSC_c17330 6e16824d4b56081ac69abfeb3fd645fe 553 Gene3D G3DSA:1.10.3720.10 51 253 1.8E-22 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c17330 6e16824d4b56081ac69abfeb3fd645fe 553 Gene3D G3DSA:1.10.3720.10 350 547 2.9E-16 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c17330 6e16824d4b56081ac69abfeb3fd645fe 553 SUPERFAMILY SSF161098 51 247 2.09E-19 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c17330 6e16824d4b56081ac69abfeb3fd645fe 553 SUPERFAMILY SSF161098 350 539 3.14E-16 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c17330 6e16824d4b56081ac69abfeb3fd645fe 553 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 368 551 1.6E-12 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c17330 6e16824d4b56081ac69abfeb3fd645fe 553 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 246 2.0E-11 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c13300 d49c92825b5670fed6820607337357e0 393 SUPERFAMILY SSF88713 26 209 4.7E-44 T 12-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 TSC_c13300 d49c92825b5670fed6820607337357e0 393 Gene3D G3DSA:3.20.20.370 23 208 1.1E-39 T 12-10-2018 TSC_c13300 d49c92825b5670fed6820607337357e0 393 Pfam PF01522 Polysaccharide deacetylase 34 99 3.0E-17 T 12-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 TSC_c11110 e5d666db50b600f782ce13874c68bfc0 306 Gene3D G3DSA:2.120.10.30 89 305 1.1E-21 T 12-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like TSC_c11110 e5d666db50b600f782ce13874c68bfc0 306 SUPERFAMILY SSF101898 21 277 3.92E-18 T 12-10-2018 TSC_c09510 49b879226ec3502d024c338164d6acdc 355 Pfam PF02653 Branched-chain amino acid transport system / permease component 60 330 6.6E-39 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSC_c11610 43dabcd121a150d05cc2ac1aff98a7cf 258 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 75 236 1.4E-10 T 12-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 TSC_c11610 43dabcd121a150d05cc2ac1aff98a7cf 258 SUPERFAMILY SSF56529 2 257 6.15E-71 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSC_c11610 43dabcd121a150d05cc2ac1aff98a7cf 258 Gene3D G3DSA:3.90.850.10 1 258 5.4E-77 T 12-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 TSC_c00160 9319be42244f370abab95faa728f4594 179 Pfam PF04290 Tripartite ATP-independent periplasmic transporters, DctQ component 30 161 1.1E-28 T 12-10-2018 IPR007387 TRAP transporter, small membrane protein DctQ TSC_c11290 93363a11fd0e84d2a81cb614dc712e4f 219 Pfam PF01594 AI-2E family transporter 10 217 2.8E-32 T 12-10-2018 IPR002549 Transmembrane protein TqsA-like TSC_c17060 ce78ef4c350726f03b06b42f0cc1a552 90 Gene3D G3DSA:3.30.110.20 1 90 1.8E-39 T 12-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 TSC_c17060 ce78ef4c350726f03b06b42f0cc1a552 90 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 4 84 5.0E-39 T 12-10-2018 IPR007347 Sporulation stage V, protein S TSC_c17060 ce78ef4c350726f03b06b42f0cc1a552 90 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 83 2.3E-37 T 12-10-2018 IPR007347 Sporulation stage V, protein S TSC_c12870 6f02a8c011bd8882d0983127667654ed 302 SUPERFAMILY SSF161098 15 296 8.18E-40 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c12870 6f02a8c011bd8882d0983127667654ed 302 Gene3D G3DSA:1.10.3720.10 14 298 5.2E-38 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c12870 6f02a8c011bd8882d0983127667654ed 302 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 172 288 8.4E-16 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c01400 e37197dcffb1f3f91789bf3fe39aacf0 280 SUPERFAMILY SSF161098 9 280 5.23E-71 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c01400 e37197dcffb1f3f91789bf3fe39aacf0 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 272 4.4E-18 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c01400 e37197dcffb1f3f91789bf3fe39aacf0 280 Gene3D G3DSA:1.10.3720.10 7 271 2.7E-63 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c18200 e33ac93b931c62a4d6f347513ffdd25a 69 Gene3D G3DSA:3.30.70.100 1 66 2.2E-7 T 12-10-2018 TSC_c06310 fea0739f6bb952cf9ab7f905c3c2bbab 144 Pfam PF06271 RDD family 3 126 7.6E-31 T 12-10-2018 IPR010432 RDD TSC_c00850 48b4c45460a9dc80d4378f4a1ee0685e 92 Pfam PF13559 Domain of unknown function (DUF4129) 4 67 9.6E-12 T 12-10-2018 IPR025403 Domain of unknown function DUF4129 TSC_c02190 c9ddaba90ab2a8685713364d1b71a5d4 100 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 9 92 1.1E-28 T 12-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 TSC_c11410 b3ee4bbd40ff96d2202531a69ba6a58f 303 SUPERFAMILY SSF51556 13 294 3.21E-23 T 12-10-2018 IPR032466 Metal-dependent hydrolase TSC_c11410 b3ee4bbd40ff96d2202531a69ba6a58f 303 Gene3D G3DSA:3.20.20.140 148 298 2.9E-9 T 12-10-2018 TSC_c10960 18b2f630352e5d3e7844fb713fd41ed6 389 Pfam PF00999 Sodium/hydrogen exchanger family 8 362 6.1E-35 T 12-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 TSC_c10960 18b2f630352e5d3e7844fb713fd41ed6 389 Gene3D G3DSA:1.20.1530.20 4 373 2.4E-51 T 12-10-2018 IPR038770 Sodium/solute symporter superfamily TSC_c01360 340b5e7a908de879153c5fcfab68a834 156 Pfam PF14326 Domain of unknown function (DUF4384) 46 116 1.1E-6 T 12-10-2018 IPR025493 Domain of unknown function DUF4384 TSC_c07760 86c8d4e5f9e86d8f063dc7b75879be4a 119 Pfam PF01934 Protein of unknown function DUF86 15 111 3.1E-22 T 12-10-2018 IPR008201 Protein of unknown function DUF86 TSC_c24820 14bfbf1914bbd4bd43fa9957621ea768 264 Pfam PF02517 CAAX protease self-immunity 126 225 5.1E-12 T 12-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 TSC_c00080 fe1b021e98d1edce6db8626fb28ba4e4 265 Gene3D G3DSA:2.60.120.560 98 254 5.5E-13 T 12-10-2018 TSC_c23060 f8d7c65685413078036f50f9757e506d 158 Pfam PF04306 Protein of unknown function (DUF456) 21 155 2.3E-31 T 12-10-2018 IPR007403 Protein of unknown function DUF456 TSC_c11000 4dd39b2a4931eddcedd989488a44362e 118 Gene3D G3DSA:3.30.70.120 8 118 5.2E-38 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TSC_c11000 4dd39b2a4931eddcedd989488a44362e 118 SUPERFAMILY SSF54913 13 111 3.11E-31 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TSC_c11000 4dd39b2a4931eddcedd989488a44362e 118 Pfam PF02641 Uncharacterized ACR, COG1993 16 110 1.8E-34 T 12-10-2018 IPR003793 Domain of unknown function DUF190 TSC_c23020 c4b77e9928155678144f9fa4a3d06078 379 Pfam PF04294 VanW like protein 151 279 3.5E-43 T 12-10-2018 IPR007391 Vancomycin resistance VanW TSC_c07130 0b2d368a39660ea0a2902861ca415b37 362 Pfam PF02585 GlcNAc-PI de-N-acetylase 86 250 5.6E-25 T 12-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 TSC_c07130 0b2d368a39660ea0a2902861ca415b37 362 Gene3D G3DSA:3.40.50.10320 80 342 9.4E-45 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TSC_c07130 0b2d368a39660ea0a2902861ca415b37 362 SUPERFAMILY SSF102588 82 338 3.66E-42 T 12-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 TSC_c05540 24e1724c321d81dbfc7d8bdecb4d27bc 145 Pfam PF10025 Uncharacterized conserved protein (DUF2267) 17 141 3.9E-41 T 12-10-2018 IPR018727 Protein of unknown function DUF2267 TSC_c05540 24e1724c321d81dbfc7d8bdecb4d27bc 145 Gene3D G3DSA:1.10.490.110 1 145 2.5E-65 T 12-10-2018 TSC_c15510 6728ab7996d2cf982ae7b57f427bfaa3 437 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 11 425 3.5E-99 T 12-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit TSC_c15510 6728ab7996d2cf982ae7b57f427bfaa3 437 PIRSF PIRSF006066 5 437 4.1E-87 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSC_c15510 6728ab7996d2cf982ae7b57f427bfaa3 437 TIGRFAM TIGR00786 dctM: TRAP transporter, DctM subunit 21 431 1.9E-104 T 12-10-2018 IPR004681 TRAP transporter large membrane protein DctM GO:0016021 TSC_c02330 d0a239a9787f28be9a0a4d0cccc2f880 216 Pfam PF03591 AzlC protein 10 143 1.9E-38 T 12-10-2018 IPR011606 Branched-chain amino acid transport, permease TSC_c17720 233dbfe2c1ece1bade4c75b9ed27b9f8 395 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 7.3E-15 T 12-10-2018 TSC_c17720 233dbfe2c1ece1bade4c75b9ed27b9f8 395 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 7.3E-15 T 12-10-2018 TSC_c17720 233dbfe2c1ece1bade4c75b9ed27b9f8 395 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 7.3E-15 T 12-10-2018 TSC_c17720 233dbfe2c1ece1bade4c75b9ed27b9f8 395 SUPERFAMILY SSF51905 7 316 2.76E-37 T 12-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily TSC_c17720 233dbfe2c1ece1bade4c75b9ed27b9f8 395 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 305 2.8E-52 T 12-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 TSC_c17720 233dbfe2c1ece1bade4c75b9ed27b9f8 395 Gene3D G3DSA:3.50.50.100 4 376 1.6E-109 T 12-10-2018 TSC_c17720 233dbfe2c1ece1bade4c75b9ed27b9f8 395 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 278 296 7.7E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c17720 233dbfe2c1ece1bade4c75b9ed27b9f8 395 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 147 171 7.7E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c17720 233dbfe2c1ece1bade4c75b9ed27b9f8 395 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 7 29 7.7E-10 T 12-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 TSC_c18110 df8e03746f51cb0b2c1c06bc62d3d42a 203 SUPERFAMILY SSF52833 28 196 3.06E-43 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TSC_c18110 df8e03746f51cb0b2c1c06bc62d3d42a 203 Pfam PF13462 Thioredoxin 29 197 1.1E-38 T 12-10-2018 IPR012336 Thioredoxin-like fold TSC_c18110 df8e03746f51cb0b2c1c06bc62d3d42a 203 Gene3D G3DSA:3.40.30.10 20 203 1.9E-51 T 12-10-2018 TSC_c01170 6f4b13c582a84d9da0d0ce4d173c73b9 104 Pfam PF04977 Septum formation initiator 34 102 4.2E-11 T 12-10-2018 IPR007060 Septum formation initiator FtsL/DivIC TSC_c24850 accfab34c0ddda98825b031ca469e152 234 Pfam PF09985 C-terminal binding-module, SLH-like, of glucodextranase 5 193 4.5E-14 T 12-10-2018 IPR019248 Glucodextranase-like, C-terminal TSC_c24850 accfab34c0ddda98825b031ca469e152 234 SUPERFAMILY SSF49344 3 206 1.61E-34 T 12-10-2018 TSC_c24850 accfab34c0ddda98825b031ca469e152 234 Gene3D G3DSA:2.60.40.1190 3 135 1.5E-13 T 12-10-2018 TSC_c02420 8e062a422d27cd5547b1493294de784f 142 Pfam PF09969 Uncharacterized conserved protein (DUF2203) 4 121 2.5E-33 T 12-10-2018 IPR018699 Protein of unknown function DUF2203 TSC_c02420 8e062a422d27cd5547b1493294de784f 142 PIRSF PIRSF016498 2 129 3.9E-23 T 12-10-2018 IPR018699 Protein of unknown function DUF2203 TSC_c03840 159a062217e67a139d5960795519b0b1 70 Pfam PF09851 Short C-terminal domain 44 69 1.3E-10 T 12-10-2018 IPR018649 SHOCT domain TSC_c07880 5fae238a6ccec2b4e91dc79c7100108f 204 Gene3D G3DSA:3.40.50.2020 106 201 3.0E-12 T 12-10-2018 TSC_c07880 5fae238a6ccec2b4e91dc79c7100108f 204 Pfam PF00156 Phosphoribosyl transferase domain 110 193 2.2E-6 T 12-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 TSC_c07880 5fae238a6ccec2b4e91dc79c7100108f 204 SUPERFAMILY SSF53271 26 198 1.88E-18 T 12-10-2018 IPR029057 Phosphoribosyltransferase-like TSC_c16770 cf38440576fcbff66b7710ddbdfa3197 370 Pfam PF02687 FtsX-like permease family 272 366 3.0E-8 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TSC_c21410 ce7c8d63517ac02fabe032d110644318 161 Gene3D G3DSA:2.60.120.1140 26 152 1.7E-38 T 12-10-2018 IPR038695 Saro_0823-like superfamily TSC_c21410 ce7c8d63517ac02fabe032d110644318 161 Pfam PF02643 Uncharacterized ACR, COG1430 48 151 5.2E-32 T 12-10-2018 IPR003795 Protein of unknown function DUF192 TSC_c10350 276a8b03d14ab8f8d71254a0e5de75b9 396 Pfam PF02687 FtsX-like permease family 282 387 6.7E-9 T 12-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 TSC_c10350 276a8b03d14ab8f8d71254a0e5de75b9 396 Pfam PF12704 MacB-like periplasmic core domain 18 220 8.1E-10 T 12-10-2018 IPR025857 MacB-like periplasmic core domain TSC_c24620 a2faff423bb1d90151eac80c3619c9f1 342 Gene3D G3DSA:1.10.10.10 1 79 1.4E-21 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c24620 a2faff423bb1d90151eac80c3619c9f1 342 SUPERFAMILY SSF46785 2 80 6.24E-16 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c04900 298237804c5e107544af7add70c9fcc3 140 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 8 62 8.8E-5 T 12-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system TSC_c04900 298237804c5e107544af7add70c9fcc3 140 Gene3D G3DSA:3.30.460.40 5 140 9.7E-15 T 12-10-2018 TSC_c04900 298237804c5e107544af7add70c9fcc3 140 SUPERFAMILY SSF81301 4 140 1.18E-17 T 12-10-2018 TSC_c08720 943417c2066771f2d484fe1cd25c1e9e 104 Pfam PF16999 Vacuolar (H+)-ATPase G subunit 1 104 2.2E-30 T 12-10-2018 TSC_c03200 445b41fece0fbe251f70542298a0b58e 322 Pfam PF01551 Peptidase family M23 217 311 5.7E-34 T 12-10-2018 IPR016047 Peptidase M23 TSC_c03200 445b41fece0fbe251f70542298a0b58e 322 Gene3D G3DSA:2.70.70.10 160 317 8.1E-49 T 12-10-2018 IPR011055 Duplicated hybrid motif TSC_c03200 445b41fece0fbe251f70542298a0b58e 322 SUPERFAMILY SSF51261 188 315 1.1E-52 T 12-10-2018 IPR011055 Duplicated hybrid motif TSC_c10150 c506e798cc126bb87b2eb945c37b21bf 506 Pfam PF13148 Protein of unknown function (DUF3987) 55 418 2.6E-82 T 12-10-2018 IPR025048 Protein of unknown function DUF3987) TSC_c06870 10f9f32b433ed4298dfa846b030635dd 577 SUPERFAMILY SSF52540 131 556 3.48E-12 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c06870 10f9f32b433ed4298dfa846b030635dd 577 Gene3D G3DSA:3.40.50.300 380 562 7.1E-16 T 12-10-2018 TSC_c10790 3e2cb3060385bcbc9b490deb8d75fc5a 346 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 1 335 7.4E-63 T 12-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 TSC_c10790 3e2cb3060385bcbc9b490deb8d75fc5a 346 Gene3D G3DSA:3.30.420.40 134 306 1.5E-78 T 12-10-2018 TSC_c10790 3e2cb3060385bcbc9b490deb8d75fc5a 346 SUPERFAMILY SSF53067 1 320 2.81E-14 T 12-10-2018 TSC_c10790 3e2cb3060385bcbc9b490deb8d75fc5a 346 Gene3D G3DSA:3.30.420.40 8 335 1.5E-78 T 12-10-2018 TSC_c06260 74538588591b8d9da714a68f3b05fcf0 176 Pfam PF09335 SNARE associated Golgi protein 26 145 7.9E-16 T 12-10-2018 IPR032816 SNARE associated Golgi protein TSC_c23760 a2ceb0bdc068f726b834008e91057272 308 Pfam PF14332 Domain of unknown function (DUF4388) 51 148 4.5E-11 T 12-10-2018 IPR025497 Domain of unknown function DUF4388 TSC_c09310 1d1d78d52b40ba53b8aa878cf61f4d75 132 Pfam PF01219 Prokaryotic diacylglycerol kinase 23 121 2.0E-30 T 12-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 TSC_c09310 1d1d78d52b40ba53b8aa878cf61f4d75 132 Gene3D G3DSA:1.10.3830.10 11 125 3.7E-35 T 12-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 TSC_c09550 0bf8bc0e527db57cc4fb47317e208098 291 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 275 1.8E-35 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSC_c23150 2cfe7f761504695c998645b903df8c3b 196 Pfam PF06168 Protein of unknown function (DUF981) 1 189 6.6E-38 T 12-10-2018 IPR009324 Protein of unknown function DUF981 TSC_c17310 2606acb14208fc453c06bcccaa495fa3 172 Pfam PF04239 Protein of unknown function (DUF421) 97 159 7.0E-13 T 12-10-2018 IPR007353 Protein of unknown function DUF421 TSC_c17310 2606acb14208fc453c06bcccaa495fa3 172 Gene3D G3DSA:3.30.240.20 89 158 5.4E-18 T 12-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily TSC_c03170 0b843e4f2b03332feaf87f032440d7a9 75 SUPERFAMILY SSF47598 2 43 2.98E-5 T 12-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 TSC_c07840 8dffdb4fe94dc94df90269f6ad349315 2694 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 2411 2674 2.4E-18 T 12-10-2018 IPR007452 Translocation and assembly module TamB TSC_c24510 84e1db33d4418930c3f921339b649171 72 Pfam PF10049 Protein of unknown function (DUF2283) 2 49 2.0E-19 T 12-10-2018 IPR019270 Protein of unknown function DUF2283 TSC_c11260 03f38076bc4b26e1b494a4f3f5a55b18 278 Pfam PF01925 Sulfite exporter TauE/SafE 11 271 1.1E-47 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TSC_c10340 cde733f686b4f73d2a623a2a5172e738 147 Gene3D G3DSA:1.10.10.10 1 86 4.2E-23 T 12-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily TSC_c10340 cde733f686b4f73d2a623a2a5172e738 147 Gene3D G3DSA:1.10.287.160 87 147 1.7E-5 T 12-10-2018 TSC_c10340 cde733f686b4f73d2a623a2a5172e738 147 SUPERFAMILY SSF46785 4 107 7.98E-12 T 12-10-2018 IPR036390 Winged helix DNA-binding domain superfamily TSC_c18370 fcce3c0755f78fd54457284a6b4b5189 557 SUPERFAMILY SSF52540 126 266 6.35E-8 T 12-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase TSC_c16530 a2972bfdc58a8a8476fb1cf8971a3637 253 Pfam PF03524 Conjugal transfer protein 42 134 6.1E-7 T 12-10-2018 IPR010258 Conjugal transfer, TrbG/VirB9/CagX TSC_c10760 5ac75e876521d84c984ddd43b4aeace0 335 SUPERFAMILY SSF161098 92 318 6.8E-17 T 12-10-2018 IPR035906 MetI-like superfamily TSC_c10760 5ac75e876521d84c984ddd43b4aeace0 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 334 2.3E-42 T 12-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 TSC_c18280 5d3b8065f71a560311ef575a49dac2b0 248 Pfam PF01925 Sulfite exporter TauE/SafE 3 237 2.8E-46 T 12-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 TSC_c18550 d6d3b21518f475d2796e59e8f3380014 328 Gene3D G3DSA:3.40.1000.10 51 193 3.0E-7 T 12-10-2018 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich TSC_c11690 3c9715e2aa69cb2ff73947802f49134e 232 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 232 34.298 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TSC_c11690 3c9715e2aa69cb2ff73947802f49134e 232 Pfam PF02654 Cobalamin-5-phosphate synthase 8 221 3.6E-41 T 12-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 TSC_c13010 65e6cfac4dd4f54c9cc18d3ebccf27f2 92 Gene3D G3DSA:3.30.450.40 2 92 1.1E-5 T 12-10-2018 IPR029016 GAF-like domain superfamily TSC_c18290 23eb1dbd6567e7c22358ff6c54285ee8 109 Pfam PF03779 SPW repeat 58 102 4.5E-18 T 12-10-2018 IPR005530 SPW repeat TSC_c18290 23eb1dbd6567e7c22358ff6c54285ee8 109 Pfam PF03779 SPW repeat 6 49 6.9E-18 T 12-10-2018 IPR005530 SPW repeat TSC_c18000 41f77dbc488658f8860fe98ed937388e 279 Gene3D G3DSA:2.60.450.10 60 187 1.2E-7 T 12-10-2018 TSC_c18000 41f77dbc488658f8860fe98ed937388e 279 Pfam PF03968 OstA-like protein 29 133 5.6E-6 T 12-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal TSC_c20500 b30fb1c0609b46caf9b9b506bbccdab6 236 Pfam PF02754 Cysteine-rich domain 129 210 6.8E-12 T 12-10-2018 IPR004017 Cysteine-rich domain TSC_c20500 b30fb1c0609b46caf9b9b506bbccdab6 236 Pfam PF02754 Cysteine-rich domain 3 83 7.0E-15 T 12-10-2018 IPR004017 Cysteine-rich domain TSC_c20990 3d0f95db6e4ac87bc963aeb6ac10b04c 222 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 8 200 2.2E-45 T 12-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 TSC_c06930 3e534ab7765b3bcf2d88f7c1b1a1e5d4 253 Gene3D G3DSA:1.20.1630.10 1 253 2.1E-108 T 12-10-2018 TSC_c06930 3e534ab7765b3bcf2d88f7c1b1a1e5d4 253 Pfam PF14589 Polysulfide reductase 1 247 2.7E-47 T 12-10-2018 IPR032796 Polysulfide reductase TSC_c10290 b1c661f2f19f9607e1c71bab0fe919a7 344 Pfam PF00487 Fatty acid desaturase 53 293 9.7E-38 T 12-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 TSC_c06110 fd26f5577a0b5804aea2dc7ca469a5c4 419 SUPERFAMILY SSF52317 260 386 7.78E-5 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c24680 cf8e871f3913014a1c425075cba29dc7 240 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 6 164 6.5E-13 T 12-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain TSC_c24680 cf8e871f3913014a1c425075cba29dc7 240 Gene3D G3DSA:3.40.50.300 1 168 1.7E-6 T 12-10-2018 TSC_c05070 df5a36686faebabec150b0de1f9a411a 442 Pfam PF02653 Branched-chain amino acid transport system / permease component 113 422 3.0E-46 T 12-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 TSC_c16360 69f9c08e7668ba5e3ced3f3294551ae0 116 Pfam PF04956 TrbC/VIRB2 family 17 109 4.3E-7 T 12-10-2018 IPR007039 Conjugal transfer TrbC/type IV secretion VirB2 TSC_c18770 ace5fac6eaff061b1092c9ae9f972aed 224 Pfam PF01882 Protein of unknown function DUF58 26 100 8.9E-16 T 12-10-2018 IPR002881 Domain of unknown function DUF58 TSC_c15950 2156e3f5ff3ac3a3b40d77ccca54bf6f 99 Pfam PF14216 Domain of unknown function (DUF4326) 1 74 1.0E-16 T 12-10-2018 IPR025475 Protein of unknown function DUF4326) TSC_c13710 f843f50ca3713c26cdb3ac8643250114 226 Pfam PF04298 Putative neutral zinc metallopeptidase 6 220 1.1E-82 T 12-10-2018 IPR007395 Putative neutral zinc metallopeptidase TSC_c06250 ba74e7411b27a2b52d669154234ab721 100 SUPERFAMILY SSF54913 1 98 7.51E-24 T 12-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta TSC_c06250 ba74e7411b27a2b52d669154234ab721 100 Gene3D G3DSA:3.30.70.120 2 100 9.6E-33 T 12-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal TSC_c19040 6a711a6d88e536c05b47a16655aec053 318 Pfam PF12679 ABC-2 family transporter protein 12 315 2.5E-35 T 12-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 TSC_c20680 582eb63cf65071a6d3a097dbae3f259c 207 Pfam PF04350 Pilus assembly protein, PilO 45 179 2.0E-8 T 12-10-2018 IPR007445 Pilus assembly protein, PilO TSC_c20680 582eb63cf65071a6d3a097dbae3f259c 207 Gene3D G3DSA:3.30.70.60 82 190 4.4E-6 T 12-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 TSC_c08900 251519a62ed9cafae7931ec5dc2c7b1e 222 SUPERFAMILY SSF117070 7 131 7.98E-6 T 12-10-2018 TSC_c00300 40a26ccb941c58875c5650a5ec10932f 373 PRINTS PR00164 ABC-2 type transport system membrane protein signature 294 313 5.1E-8 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSC_c00300 40a26ccb941c58875c5650a5ec10932f 373 PRINTS PR00164 ABC-2 type transport system membrane protein signature 257 281 5.1E-8 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSC_c00300 40a26ccb941c58875c5650a5ec10932f 373 PRINTS PR00164 ABC-2 type transport system membrane protein signature 314 333 5.1E-8 T 12-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 TSC_c00300 40a26ccb941c58875c5650a5ec10932f 373 Pfam PF12698 ABC-2 family transporter protein 25 363 4.8E-49 T 12-10-2018 TSC_c03450 0bbcac27b1c473ebce4becab7925c617 450 Pfam PF03916 Polysulphide reductase, NrfD 70 391 4.0E-25 T 12-10-2018 IPR005614 NrfD family TSC_c14220 95d4672c00088356ea2891ff9aefa0a7 448 Pfam PF00361 Proton-conducting membrane transporter 101 384 2.9E-47 T 12-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 TSC_c15280 274bb127300e4ba20f41c596b2ae887f 145 Pfam PF04238 Protein of unknown function (DUF420) 8 133 5.6E-38 T 12-10-2018 IPR007352 Protein of unknown function DUF420 TSC_c03390 de36bf87a3bec98a089996bb5fb51191 237 Gene3D G3DSA:3.40.50.880 16 236 4.2E-22 T 12-10-2018 IPR029062 Class I glutamine amidotransferase-like TSC_c17560 a00d2e1d22917d86b0612cfc64bad510 131 SUPERFAMILY SSF52833 3 113 9.6E-5 T 12-10-2018 IPR036249 Thioredoxin-like superfamily TSC_c15690 6a0e8defae25a88ca418d07788f3b8c0 219 Pfam PF02163 Peptidase family M50 130 196 4.2E-8 T 12-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 TSC_c05290 c25228be425d92b10ca2f7977207e689 362 Pfam PF00953 Glycosyl transferase family 4 97 248 2.8E-33 T 12-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 TSC_c00270 70bcdae4ad4034e7b99424b66a6ad280 220 Pfam PF04012 PspA/IM30 family 3 218 3.2E-51 T 12-10-2018 IPR007157 PspA/IM30 TSC_c22550 1ecaf8e7b132ceac4b9a2de23bbb70bb 113 Pfam PF03780 Asp23 family, cell envelope-related function 2 110 5.9E-25 T 12-10-2018 IPR005531 Alkaline shock protein Asp23