locus-tag	class	description
KQ693_00005	COG0542	response to heat
KQ693_00045	COG0490	domain, Protein
KQ693_00050	COG0475	glutathione-regulated potassium exporter activity
KQ693_00065	COG0617	tRNA 3'-terminal CCA addition
KQ693_00065	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KQ693_00065	COG3620	sequence-specific DNA binding
KQ693_00070	COG0475	glutathione-regulated potassium exporter activity
KQ693_00120	COG0067	glutamate synthase
KQ693_00120	COG0069	glutamate synthase activity
KQ693_00120	COG0070	glutamate synthase
KQ693_00125	COG0247	lactate metabolic process
KQ693_00130	COG1139	Iron-sulfur cluster binding protein
KQ693_00135	COG1139	Iron-sulfur cluster binding protein
KQ693_00145	COG1752	Esterase of the alpha-beta hydrolase superfamily
KQ693_00150	COG0515	serine threonine protein kinase
KQ693_00150	COG2815	serine threonine protein kinase
KQ693_00160	COG0860	N-Acetylmuramoyl-L-alanine amidase
KQ693_00170	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KQ693_00190	COG2199	diguanylate cyclase activity
KQ693_00190	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
KQ693_00200	COG0473	3-isopropylmalate dehydrogenase activity
KQ693_00230	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KQ693_00235	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KQ693_00240	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KQ693_00255	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KQ693_00255	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
KQ693_00265	COG0736	holo-[acyl-carrier-protein] synthase activity
KQ693_00280	COG1160	GTP binding
KQ693_00290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KQ693_00300	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KQ693_00300	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KQ693_00305	COG0083	homoserine kinase activity
KQ693_00320	COG0268	Binds directly to 16S ribosomal RNA
KQ693_00330	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KQ693_00350	COG0723	plastoquinol--plastocyanin reductase activity
KQ693_00360	COG3088	subunit of a heme lyase
KQ693_00360	COG4235	cytochrome complex assembly
KQ693_00365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KQ693_00370	COG1138	Cytochrome C-type biogenesis protein
KQ693_00375	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KQ693_00380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KQ693_00390	COG4133	protoheme IX ABC transporter activity
KQ693_00395	COG0785	Cytochrome C biogenesis protein
KQ693_00405	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KQ693_00410	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ693_00430	COG2010	Cytochrome c
KQ693_00435	COG0737	Belongs to the 5'-nucleotidase family
KQ693_00440	COG2010	Cytochrome c
KQ693_00445	COG3258	Cytochrome c
KQ693_00465	COG2010	Cytochrome c
KQ693_00470	COG3842	ATPase activity
KQ693_00490	COG0504	CTP synthase activity
KQ693_00495	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KQ693_00500	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KQ693_00525	COG2205	protein histidine kinase activity
KQ693_00535	COG2815	serine threonine protein kinase
KQ693_00535	COG0515	serine threonine protein kinase
KQ693_00540	COG0631	protein serine/threonine phosphatase activity
KQ693_00555	COG0113	porphobilinogen synthase activity
KQ693_00560	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KQ693_00565	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KQ693_00590	COG0823	Involved in the tonB-independent uptake of proteins
KQ693_00590	COG4946	Tricorn protease homolog
KQ693_00590	COG1506	peptidase
KQ693_00595	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KQ693_00600	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KQ693_00625	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KQ693_00630	COG1011	Hydrolase
KQ693_00640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KQ693_00655	COG0537	adenosine 5'-monophosphoramidase activity
KQ693_00660	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KQ693_00675	COG0135	phosphoribosylanthranilate isomerase activity
KQ693_00680	COG0483	inositol monophosphate 1-phosphatase activity
KQ693_00690	COG1310	metal-dependent protease of the Pad1 Jab1 superfamily
KQ693_00695	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KQ693_00700	COG0714	Associated with various cellular activities
KQ693_00705	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KQ693_00705	COG0574	Belongs to the PEP-utilizing enzyme family
KQ693_00710	COG1272	protein, Hemolysin III
KQ693_00720	COG3850	Histidine kinase
KQ693_00720	COG5002	protein histidine kinase activity
KQ693_00755	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KQ693_00770	COG0546	phosphoglycolate phosphatase activity
KQ693_00785	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KQ693_00795	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KQ693_00805	COG0047	phosphoribosylformylglycinamidine synthase activity
KQ693_00815	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KQ693_00820	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
KQ693_00830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KQ693_00835	COG0497	DNA recombination
KQ693_00845	COG2095	MarC family integral membrane protein
KQ693_00850	COG1438	arginine binding
KQ693_00855	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KQ693_00865	COG0194	GDP metabolic process
KQ693_00875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KQ693_00880	COG2385	sporulation resulting in formation of a cellular spore
KQ693_00885	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
KQ693_00895	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
KQ693_00925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KQ693_00930	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KQ693_00945	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
KQ693_00975	COG0203	ribosomal protein L17
KQ693_00985	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KQ693_00990	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KQ693_00995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KQ693_01005	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KQ693_01015	COG0563	adenylate kinase activity
KQ693_01020	COG0201	protein transport
KQ693_01080	COG0255	Belongs to the universal ribosomal protein uL29 family
KQ693_01085	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KQ693_01090	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KQ693_01100	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KQ693_01105	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KQ693_01110	COG0089	rRNA binding
KQ693_01115	COG0088	Forms part of the polypeptide exit tunnel
KQ693_01125	COG0051	transcription antitermination factor activity, RNA binding
KQ693_01130	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KQ693_01140	COG0049	tRNA binding
KQ693_01225	COG1461	Dihydroxyacetone kinase
KQ693_01235	COG0686	Belongs to the AlaDH PNT family
KQ693_01240	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KQ693_01245	COG1024	Enoyl-CoA hydratase
KQ693_01250	COG1187	pseudouridine synthase activity
KQ693_01255	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KQ693_01265	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KQ693_01275	COG0512	Glutamine amidotransferase of anthranilate synthase
KQ693_01280	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KQ693_01285	COG1012	belongs to the aldehyde dehydrogenase family
KQ693_01290	COG0506	proline dehydrogenase activity
KQ693_01295	COG1802	Transcriptional regulator
KQ693_01310	COG0156	8-amino-7-oxononanoate synthase activity
KQ693_01325	COG0187	DNA topoisomerase II activity
KQ693_01330	COG1643	Atp-dependent helicase
KQ693_01340	COG1063	alcohol dehydrogenase
KQ693_01390	COG1605	Chorismate mutase
KQ693_01390	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KQ693_01395	COG0805	protein transport
KQ693_01405	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KQ693_01410	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KQ693_01425	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KQ693_01430	COG0792	nuclease activity
KQ693_01440	COG0492	ferredoxin-NADP+ reductase activity
KQ693_01445	COG1028	Short-chain dehydrogenase reductase Sdr
KQ693_01450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KQ693_01465	COG1187	pseudouridine synthase activity
KQ693_01475	COG1459	type II secretion system
KQ693_01480	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KQ693_01505	COG2165	general secretion pathway protein
KQ693_01510	COG2720	vancomycin resistance protein
KQ693_01520	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KQ693_01525	COG0427	acetyl-CoA hydrolase
KQ693_01530	COG0686	Belongs to the AlaDH PNT family
KQ693_01545	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KQ693_01550	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KQ693_01555	COG0071	Belongs to the small heat shock protein (HSP20) family
KQ693_01565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ693_01575	COG1764	response to oxidative stress
KQ693_01585	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KQ693_01600	COG3842	ATPase activity
KQ693_01605	COG0101	tRNA pseudouridine synthase activity
KQ693_01610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQ693_01615	COG0601	transmembrane transport
KQ693_01620	COG0747	negative chemotaxis
KQ693_01625	COG0316	Belongs to the HesB IscA family
KQ693_01635	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KQ693_01650	COG1166	arginine decarboxylase activity
KQ693_01660	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KQ693_01665	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KQ693_01675	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KQ693_01700	COG0366	Alpha amylase catalytic
KQ693_01710	COG1193	negative regulation of DNA recombination
KQ693_01730	COG2226	methyltransferase
KQ693_01735	COG4603	Belongs to the binding-protein-dependent transport system permease family
KQ693_01740	COG1079	Belongs to the binding-protein-dependent transport system permease family
KQ693_01750	COG1774	PSP1 C-terminal conserved region
KQ693_01755	COG0470	DNA polymerase III
KQ693_01795	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KQ693_01810	COG1653	transport
KQ693_01830	COG0723	plastoquinol--plastocyanin reductase activity
KQ693_01835	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KQ693_01840	COG0539	negative regulation of cytoplasmic translation
KQ693_01870	COG1115	amino acid carrier protein
KQ693_01890	COG1489	DNA binding
KQ693_01925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
KQ693_01930	COG1355	regulation of microtubule-based process
KQ693_01945	COG1011	Hydrolase
KQ693_01960	COG0589	response to stress
KQ693_01965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KQ693_01970	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KQ693_01980	COG1940	carbohydrate kinase activity
KQ693_02025	COG0302	gtp cyclohydrolase
KQ693_02045	COG1217	gtp-binding protein TYPA
KQ693_02075	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KQ693_02095	COG0395	ABC-type sugar transport system, permease component
KQ693_02100	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KQ693_02110	COG1131	(ABC) transporter
KQ693_02130	COG0556	nucleotide-excision repair
KQ693_02140	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KQ693_02200	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
KQ693_02205	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
KQ693_02245	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
KQ693_02250	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KQ693_02255	COG0343	queuine tRNA-ribosyltransferase activity
KQ693_02260	COG0628	permease
KQ693_02280	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KQ693_02285	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KQ693_02295	COG0436	Aminotransferase
KQ693_02305	COG1597	lipid kinase activity
KQ693_02320	COG0123	including yeast histone deacetylase and acetoin utilization protein
KQ693_02325	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KQ693_02335	COG0004	ammonium transporteR
KQ693_02340	COG0347	Belongs to the P(II) protein family
KQ693_02345	COG1420	regulation of RNA biosynthetic process
KQ693_02350	COG0314	molybdopterin synthase activity
KQ693_02360	COG4636	protein conserved in cyanobacteria
KQ693_02365	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KQ693_02370	COG1960	acyl-CoA dehydrogenase activity
KQ693_02380	COG0495	leucyl-tRNA aminoacylation
KQ693_02390	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KQ693_02395	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
KQ693_02410	COG2096	Adenosyltransferase
KQ693_02420	COG4555	ABC transporter
KQ693_02425	COG1668	transmembrane transport
KQ693_02450	COG1660	Displays ATPase and GTPase activities
KQ693_02455	COG0391	Required for morphogenesis under gluconeogenic growth conditions
KQ693_02470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KQ693_02475	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KQ693_02495	COG0072	phenylalanine-tRNA ligase activity
KQ693_02495	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ693_02505	COG0205	6-phosphofructokinase activity
KQ693_02510	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KQ693_02520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KQ693_02525	COG0584	glycerophosphoryl diester phosphodiesterase
KQ693_02540	COG2333	competence protein COMEC
KQ693_02540	COG0658	competence protein
KQ693_02545	COG1475	DNA binding
KQ693_02550	COG1192	Involved in chromosome partitioning
KQ693_02555	COG0357	Ribosomal RNA small subunit methyltransferase G
KQ693_02560	COG0445	tRNA wobble uridine modification
KQ693_02565	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KQ693_02570	COG0592	DNA-directed DNA polymerase activity
KQ693_02575	COG0148	phosphopyruvate hydratase activity
KQ693_02580	COG0469	pyruvate kinase activity
KQ693_02605	COG0631	protein serine/threonine phosphatase activity
KQ693_02610	COG0105	UTP biosynthetic process
KQ693_02620	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KQ693_02645	COG0315	cyclic pyranopterin monophosphate synthase activity
KQ693_02660	COG2010	Cytochrome c
KQ693_02665	COG0535	radical SAM domain protein
KQ693_02675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ693_02680	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KQ693_02690	COG1842	Phage shock protein A
KQ693_02715	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KQ693_02725	COG1278	Cold shock
KQ693_02730	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KQ693_02750	COG2860	membrane
KQ693_02755	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KQ693_02775	COG1547	Domain of unknown function (DUF309)
KQ693_02800	COG2414	aldehyde ferredoxin oxidoreductase
KQ693_02810	COG0604	alcohol dehydrogenase
KQ693_02825	COG1902	pentaerythritol trinitrate reductase activity
KQ693_02840	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KQ693_02870	COG1131	(ABC) transporter
KQ693_02895	COG3956	TIGRFAM MazG family protein
KQ693_02905	COG0693	protein deglycase activity
KQ693_02910	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KQ693_02920	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KQ693_02925	COG1937	Protein conserved in bacteria
KQ693_02935	COG0674	pyruvate-flavodoxin oxidoreductase activity
KQ693_02935	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KQ693_02940	COG1013	pyruvate-flavodoxin oxidoreductase activity
KQ693_02965	COG0459	protein refolding
KQ693_02970	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KQ693_02980	COG0714	Associated with various cellular activities
KQ693_02990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KQ693_03000	COG0166	Belongs to the GPI family
KQ693_03005	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
KQ693_03010	COG0109	protoheme IX farnesyltransferase activity
KQ693_03010	COG1612	heme a metabolic process
KQ693_03020	COG1845	cytochrome c oxidase, subunit III
KQ693_03020	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KQ693_03040	COG1845	cytochrome c oxidase, subunit III
KQ693_03050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KQ693_03055	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KQ693_03080	COG3706	GGDEF domain
KQ693_03095	COG5002	protein histidine kinase activity
KQ693_03095	COG5001	Diguanylate cyclase
KQ693_03105	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KQ693_03120	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KQ693_03125	COG2814	Major facilitator Superfamily
KQ693_03130	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KQ693_03135	COG0581	inorganic phosphate transmembrane transporter activity
KQ693_03140	COG0573	inorganic phosphate transmembrane transporter activity
KQ693_03150	COG0482	sulfurtransferase activity
KQ693_03160	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KQ693_03165	COG0735	belongs to the Fur family
KQ693_03180	COG0583	DNA-binding transcription factor activity
KQ693_03185	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
KQ693_03190	COG0508	dehydrogenase complex catalyzes the overall conversion of
KQ693_03195	COG0181	hydroxymethylbilane synthase activity
KQ693_03205	COG0285	dihydrofolate synthase activity
KQ693_03210	COG0436	Aminotransferase
KQ693_03215	COG0521	Mo-molybdopterin cofactor biosynthetic process
KQ693_03225	COG0395	ABC-type sugar transport system, permease component
KQ693_03230	COG1175	transmembrane transport
KQ693_03235	COG2182	Extracellular solute-binding protein
KQ693_03245	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KQ693_03250	COG0154	amidase activity
KQ693_03255	COG0301	tRNA thio-modification
KQ693_03265	COG0243	molybdopterin cofactor binding
KQ693_03275	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KQ693_03290	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KQ693_03300	COG1653	transport
KQ693_03315	COG0033	Phosphoglucomutase
KQ693_03330	COG2814	Major facilitator Superfamily
KQ693_03340	COG0517	IMP dehydrogenase activity
KQ693_03340	COG0516	GMP reductase activity
KQ693_03345	COG1950	PFAM Membrane protein of
KQ693_03365	COG0406	alpha-ribazole phosphatase activity
KQ693_03370	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KQ693_03375	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KQ693_03385	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KQ693_03390	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
KQ693_03395	COG1496	oxidoreductase activity
KQ693_03405	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KQ693_03410	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KQ693_03415	COG1993	acr, cog1993
KQ693_03420	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KQ693_03430	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KQ693_03440	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
KQ693_03445	COG1335	isochorismatase
KQ693_03450	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KQ693_03455	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KQ693_03480	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
KQ693_03485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KQ693_03490	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KQ693_03495	COG0250	Participates in transcription elongation, termination and antitermination
KQ693_03505	COG0081	regulation of translation
KQ693_03510	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KQ693_03515	COG0222	ribosome binding
KQ693_03520	COG0163	prenyltransferase activity
KQ693_03525	COG1960	acyl-CoA dehydrogenase activity
KQ693_03530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KQ693_03535	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KQ693_03550	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KQ693_03555	COG0066	3-isopropylmalate dehydratase activity
KQ693_03570	COG0189	ligase activity
KQ693_03575	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KQ693_03580	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KQ693_03585	COG1543	Belongs to the glycosyl hydrolase 57 family
KQ693_03590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KQ693_03590	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KQ693_03595	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KQ693_03610	COG0445	tRNA wobble uridine modification
KQ693_03620	COG1388	LysM domain
KQ693_03620	COG0791	NLP P60 protein
KQ693_03630	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KQ693_03640	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
KQ693_03645	COG0477	Major facilitator Superfamily
KQ693_03660	COG1694	Mazg nucleotide pyrophosphohydrolase
KQ693_03665	COG1803	Methylglyoxal synthase
KQ693_03675	COG2271	Major facilitator Superfamily
KQ693_03695	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KQ693_03720	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
KQ693_03725	COG0359	binds to the 23S rRNA
KQ693_03730	COG0300	oxidoreductase activity
KQ693_03740	COG0321	lipoyl(octanoyl) transferase activity
KQ693_03745	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KQ693_03770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KQ693_03785	COG1598	PFAM Uncharacterised protein family UPF0150
KQ693_03790	COG0022	dehydrogenase e1 component
KQ693_03795	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KQ693_03800	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KQ693_03825	COG2226	methyltransferase
KQ693_03830	COG0432	Pfam Uncharacterised protein family UPF0047
KQ693_03835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KQ693_03845	COG0668	transmembrane transport
KQ693_03850	COG3253	May function as heme-dependent peroxidase
KQ693_03880	COG0642	Histidine kinase
KQ693_03895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ693_03900	COG1136	(ABC) transporter
KQ693_03905	COG1136	(ABC) transporter
KQ693_03905	COG0577	efflux transmembrane transporter activity
KQ693_03915	COG0632	four-way junction helicase activity
KQ693_03920	COG1024	Enoyl-CoA hydratase
KQ693_03930	COG0508	dehydrogenase complex catalyzes the overall conversion of
KQ693_03945	COG1404	Belongs to the peptidase S8 family
KQ693_03955	COG0137	argininosuccinate synthase activity
KQ693_03960	COG0165	Argininosuccinate lyase
KQ693_03965	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KQ693_03965	COG0165	Argininosuccinate lyase
KQ693_03980	COG0505	Belongs to the CarA family
KQ693_03985	COG2759	Belongs to the formate--tetrahydrofolate ligase family
KQ693_04005	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KQ693_04010	COG0211	Belongs to the bacterial ribosomal protein bL27 family
KQ693_04015	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KQ693_04020	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KQ693_04035	COG0799	negative regulation of ribosome biogenesis
KQ693_04040	COG4636	protein conserved in cyanobacteria
KQ693_04050	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
KQ693_04090	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KQ693_04095	COG0825	malonyl-CoA metabolic process
KQ693_04115	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KQ693_04125	COG1278	Cold shock
KQ693_04130	COG0484	heat shock protein binding
KQ693_04135	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KQ693_04140	COG1968	undecaprenyl-diphosphatase activity
KQ693_04145	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KQ693_04150	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KQ693_04165	COG1309	transcriptional regulator
KQ693_04185	COG0802	atpase or kinase
KQ693_04200	COG0437	4 iron, 4 sulfur cluster binding
KQ693_04225	COG1252	NADH dehydrogenase
KQ693_04235	COG3706	GGDEF domain
KQ693_04240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KQ693_04255	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KQ693_04260	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KQ693_04265	COG1185	polyribonucleotide nucleotidyltransferase activity
KQ693_04270	COG3118	belongs to the thioredoxin family
KQ693_04275	COG0416	fatty acid biosynthetic process
KQ693_04285	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
KQ693_04300	COG0284	orotidine-5'-phosphate decarboxylase activity
KQ693_04305	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KQ693_04315	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KQ693_04335	COG0822	iron-sulfur transferase activity
KQ693_04340	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KQ693_04350	COG2132	Multicopper oxidase
KQ693_04375	COG2226	methyltransferase
KQ693_04390	COG5002	protein histidine kinase activity
KQ693_04395	COG0745	RESPONSE REGULATOR receiver
KQ693_04425	COG0719	Fe-S assembly protein
KQ693_04430	COG0719	Fe-S assembly protein
KQ693_04435	COG0396	ATPase activity
KQ693_04445	COG2224	Isocitrate lyase
KQ693_04450	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ693_04455	COG1136	(ABC) transporter
KQ693_04460	COG0577	efflux transmembrane transporter activity
KQ693_04460	COG1136	(ABC) transporter
KQ693_04470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KQ693_04480	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KQ693_04510	COG4948	Mandelate Racemase Muconate Lactonizing
KQ693_04530	COG0354	folic acid binding
KQ693_04535	COG1058	Belongs to the CinA family
KQ693_04535	COG1546	Belongs to the CinA family
KQ693_04540	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KQ693_04550	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KQ693_04550	COG1418	mRNA catabolic process
KQ693_04565	COG1077	Cell shape determining protein MreB Mrl
KQ693_04570	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KQ693_04600	COG0235	Class ii aldolase
KQ693_04620	COG1177	transmembrane transport
KQ693_04625	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KQ693_04630	COG1607	acyl-coa hydrolase
KQ693_04635	COG2154	pterin-4-alpha-carbinolamine dehydratase
KQ693_04645	COG0277	FAD linked oxidase domain protein
KQ693_04660	COG0667	Aldo Keto reductase
KQ693_04675	COG1067	ATP-dependent peptidase activity
KQ693_04680	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KQ693_04690	COG0745	RESPONSE REGULATOR receiver
KQ693_04695	COG2105	PFAM AIG2 family protein
KQ693_04710	COG0297	glycogen (starch) synthase activity
KQ693_04720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KQ693_04725	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KQ693_04740	COG0142	geranyltranstransferase activity
KQ693_04750	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KQ693_04950	COG0582	viral genome integration into host DNA
KQ693_04985	COG3335	DDE superfamily endonuclease
KQ693_05015	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KQ693_05030	COG0516	GMP reductase activity
KQ693_05030	COG0517	IMP dehydrogenase activity
KQ693_05045	COG2205	protein histidine kinase activity
KQ693_05065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQ693_05075	COG1324	tolerance protein
KQ693_05080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KQ693_05085	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KQ693_05090	COG0739	heme binding
KQ693_05090	COG1196	nuclear chromosome segregation
KQ693_05090	COG0741	lytic transglycosylase activity
KQ693_05095	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KQ693_05100	COG2197	response regulator
KQ693_05115	COG1132	(ABC) transporter
KQ693_05120	COG1132	(ABC) transporter
KQ693_05125	COG0285	dihydrofolate synthase activity
KQ693_05135	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQ693_05140	COG0601	transmembrane transport
KQ693_05145	COG0747	negative chemotaxis
KQ693_05175	COG0174	glutamine synthetase
KQ693_05180	COG0737	Belongs to the 5'-nucleotidase family
KQ693_05200	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KQ693_05205	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KQ693_05210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KQ693_05215	COG0788	formyltetrahydrofolate deformylase activity
KQ693_05230	COG2358	TRAP transporter, solute receptor (TAXI family
KQ693_05250	COG2814	Major facilitator Superfamily
KQ693_05255	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KQ693_05260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KQ693_05265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
KQ693_05285	COG2050	protein possibly involved in aromatic compounds catabolism
KQ693_05290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KQ693_05320	COG0247	lactate metabolic process
KQ693_05325	COG0277	FAD linked oxidase domain protein
KQ693_05330	COG0277	FAD linked oxidase domain protein
KQ693_05335	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KQ693_05340	COG1414	Transcriptional regulator
KQ693_05345	COG0789	Transcriptional regulator
KQ693_05355	COG2045	Belongs to the ComB family
KQ693_05360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQ693_05365	COG1136	(ABC) transporter
KQ693_05375	COG1024	Enoyl-CoA hydratase
KQ693_05390	COG0318	PFAM AMP-dependent synthetase and ligase
KQ693_05395	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ693_05400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KQ693_05415	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KQ693_05435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KQ693_05450	COG2890	protein-(glutamine-N5) methyltransferase activity
KQ693_05455	COG1837	Belongs to the UPF0109 family
KQ693_05460	COG0706	membrane insertase activity
KQ693_05465	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KQ693_05485	COG1022	Amp-dependent synthetase and ligase
KQ693_05525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ693_05530	COG0232	Belongs to the dGTPase family. Type 2 subfamily
KQ693_05535	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KQ693_05540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KQ693_05545	COG1028	Short-chain dehydrogenase reductase Sdr
KQ693_05550	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KQ693_05555	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KQ693_05560	COG0333	Belongs to the bacterial ribosomal protein bL32 family
KQ693_05590	COG1007	ATP synthesis coupled electron transport
KQ693_05595	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KQ693_05600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KQ693_05605	COG0713	ATP synthesis coupled electron transport
KQ693_05610	COG0839	Belongs to the complex I subunit 6 family
KQ693_05615	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KQ693_05620	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KQ693_05625	COG1034	ATP synthesis coupled electron transport
KQ693_05630	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KQ693_05635	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KQ693_05640	COG0649	NAD binding
KQ693_05645	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KQ693_05650	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KQ693_05655	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KQ693_05660	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KQ693_05670	COG4712	double-strand break repair protein
KQ693_05725	COG0582	viral genome integration into host DNA
KQ693_05735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KQ693_05770	COG0210	DNA helicase
KQ693_05800	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
KQ693_05990	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KQ693_05995	COG0131	Imidazoleglycerol-phosphate dehydratase
KQ693_06000	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KQ693_06005	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KQ693_06010	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KQ693_06020	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KQ693_06035	COG0586	Pfam SNARE associated Golgi protein
KQ693_06040	COG0861	Integral membrane protein TerC family
KQ693_06045	COG2151	metal-sulfur cluster biosynthetic enzyme
KQ693_06060	COG1714	RDD family
KQ693_06065	COG0616	signal peptide processing
KQ693_06070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KQ693_06075	COG0372	Belongs to the citrate synthase family
KQ693_06080	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KQ693_06090	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KQ693_06095	COG0758	DNA mediated transformation
KQ693_06095	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KQ693_06100	COG3546	catalase activity
KQ693_06105	COG0583	DNA-binding transcription factor activity
KQ693_06115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KQ693_06120	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KQ693_06125	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KQ693_06135	COG0717	Belongs to the dCTP deaminase family
KQ693_06145	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
KQ693_06145	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KQ693_06150	COG1028	Short-chain dehydrogenase reductase Sdr
KQ693_06155	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KQ693_06180	COG0515	serine threonine protein kinase
KQ693_06180	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KQ693_06190	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KQ693_06210	COG0704	Plays a role in the regulation of phosphate uptake
KQ693_06215	COG2205	protein histidine kinase activity
KQ693_06220	COG0745	RESPONSE REGULATOR receiver
KQ693_06230	COG0582	viral genome integration into host DNA
KQ693_06275	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KQ693_06300	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KQ693_06305	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KQ693_06320	COG0281	malic enzyme
KQ693_06335	COG0404	The glycine cleavage system catalyzes the degradation of glycine
KQ693_06340	COG0509	glycine decarboxylation via glycine cleavage system
KQ693_06345	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KQ693_06350	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KQ693_06370	COG0243	molybdopterin cofactor binding
KQ693_06380	COG2197	response regulator
KQ693_06390	COG0196	riboflavin kinase activity
KQ693_06415	COG2813	Specifically methylates the guanine in position
KQ693_06425	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
KQ693_06435	COG0358	DNA primase activity
KQ693_06450	COG1111	helicase
KQ693_06450	COG1205	dead DEAH box helicase
KQ693_06455	COG0456	acetyltransferase
KQ693_06465	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KQ693_06470	COG0009	L-threonylcarbamoyladenylate synthase
KQ693_06475	COG1459	type II secretion system
KQ693_06495	COG3706	GGDEF domain
KQ693_06500	COG0287	Prephenate dehydrogenase
KQ693_06505	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
KQ693_06510	COG2514	catechol 2,3-dioxygenase activity
KQ693_06515	COG2353	YceI-like domain
KQ693_06520	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
KQ693_06525	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
KQ693_06545	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KQ693_06550	COG0179	Fumarylacetoacetate (FAA) hydrolase
KQ693_06560	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KQ693_06565	COG0151	Belongs to the GarS family
KQ693_06570	COG2176	DNA-directed DNA polymerase activity
KQ693_06570	COG5002	protein histidine kinase activity
KQ693_06575	COG0745	RESPONSE REGULATOR receiver
KQ693_06580	COG2205	protein histidine kinase activity
KQ693_06590	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KQ693_06590	COG0517	IMP dehydrogenase activity
KQ693_06590	COG0617	tRNA 3'-terminal CCA addition
KQ693_06610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQ693_06615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQ693_06620	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQ693_06630	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KQ693_06630	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KQ693_06640	COG1733	regulation of RNA biosynthetic process
KQ693_06645	COG2894	cell division
KQ693_06650	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KQ693_06655	COG0772	Belongs to the SEDS family
KQ693_06660	COG3842	ATPase activity
KQ693_06665	COG1176	ABC-type spermidine putrescine transport system, permease component I
KQ693_06670	COG1177	transmembrane transport
KQ693_06675	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KQ693_06680	COG2010	Cytochrome c
KQ693_06685	COG0129	dihydroxy-acid dehydratase activity
KQ693_06690	COG1028	Short-chain dehydrogenase reductase Sdr
KQ693_06710	COG0066	3-isopropylmalate dehydratase activity
KQ693_06715	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KQ693_06725	COG0180	Tryptophanyl-tRNA synthetase
KQ693_06735	COG0438	transferase activity, transferring glycosyl groups
KQ693_06745	COG1215	transferase activity, transferring glycosyl groups
KQ693_06750	COG0562	UDP-galactopyranose mutase
KQ693_06755	COG2244	polysaccharide biosynthetic process
KQ693_06785	COG4966	pilus assembly protein PilW
KQ693_06790	COG2165	general secretion pathway protein
KQ693_06795	COG4970	Tfp pilus assembly protein FimT
KQ693_06800	COG4970	Tfp pilus assembly protein FimT
KQ693_06805	COG0183	Belongs to the thiolase family
KQ693_06825	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
KQ693_06830	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KQ693_06845	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KQ693_06850	COG1254	Belongs to the acylphosphatase family
KQ693_06860	COG1063	alcohol dehydrogenase
KQ693_06865	COG2133	pyrroloquinoline quinone binding
KQ693_06870	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KQ693_06905	COG0420	3'-5' exonuclease activity
KQ693_06910	COG0419	ATPase involved in DNA repair
KQ693_06930	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KQ693_06935	COG0612	Peptidase, M16
KQ693_06940	COG0612	Peptidase, M16
KQ693_06945	COG0697	spore germination
KQ693_06950	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQ693_06970	COG4956	integral membrane protein (PIN domain superfamily)
KQ693_06975	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KQ693_06980	COG0542	response to heat
KQ693_06985	COG0423	glycine-tRNA ligase activity
KQ693_06990	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
KQ693_07010	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KQ693_07010	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KQ693_07020	COG1024	Enoyl-CoA hydratase
KQ693_07025	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KQ693_07035	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
KQ693_07045	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KQ693_07050	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KQ693_07055	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KQ693_07065	COG0861	Integral membrane protein TerC family
KQ693_07070	COG0492	ferredoxin-NADP+ reductase activity
KQ693_07075	COG0028	Belongs to the TPP enzyme family
KQ693_07080	COG0440	acetolactate synthase activity
KQ693_07085	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KQ693_07095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KQ693_07110	COG1131	(ABC) transporter
KQ693_07140	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KQ693_07150	COG1573	uracil-dna glycosylase
KQ693_07170	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KQ693_07180	COG1404	Belongs to the peptidase S8 family
KQ693_07185	COG1316	TRANSCRIPTIONal
KQ693_07210	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQ693_07220	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
KQ693_07240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KQ693_07250	COG1269	ATP hydrolysis coupled proton transport
KQ693_07260	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
KQ693_07265	COG1527	subunit (C
KQ693_07270	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
KQ693_07275	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
KQ693_07280	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
KQ693_07285	COG1394	ATPase activity, coupled to movement of substances
KQ693_07290	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KQ693_07340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ693_07350	COG1760	l-serine dehydratase
KQ693_07360	COG0481	GTPase activity
KQ693_07370	COG1960	acyl-CoA dehydrogenase activity
KQ693_07375	COG0183	Belongs to the thiolase family
KQ693_07385	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KQ693_07390	COG1028	Short-chain dehydrogenase reductase Sdr
KQ693_07425	COG1012	belongs to the aldehyde dehydrogenase family
KQ693_07460	COG2030	dehydratase
KQ693_07470	COG0596	Alpha beta hydrolase
KQ693_07480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KQ693_07520	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KQ693_07520	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KQ693_07530	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KQ693_07540	COG0195	Participates in both transcription termination and antitermination
KQ693_07545	COG0779	Required for maturation of 30S ribosomal subunits
KQ693_07565	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KQ693_07565	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KQ693_07575	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KQ693_07575	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KQ693_07595	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KQ693_07595	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KQ693_07600	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KQ693_07600	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
KQ693_07605	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KQ693_07625	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KQ693_07630	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KQ693_07635	COG1702	phosphate starvation-inducible protein PhoH
KQ693_07645	COG4864	UPF0365 protein
KQ693_07650	COG1030	water channel activity
KQ693_07655	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KQ693_07670	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KQ693_07675	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KQ693_07680	COG0824	Thioesterase
KQ693_07690	COG0557	exoribonuclease II activity
KQ693_07695	COG1355	regulation of microtubule-based process
KQ693_07700	COG0617	tRNA 3'-terminal CCA addition
KQ693_07700	COG1353	crispr-associated protein
KQ693_07705	COG0237	dephospho-CoA kinase activity
KQ693_07710	COG4221	oxidoreductase activity
KQ693_07720	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KQ693_07755	COG0165	Argininosuccinate lyase
KQ693_07765	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KQ693_07780	COG2239	Acts as a magnesium transporter
KQ693_07795	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KQ693_07800	COG1185	polyribonucleotide nucleotidyltransferase activity
KQ693_07805	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KQ693_07820	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KQ693_07825	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KQ693_07835	COG1100	Small GTP-binding protein
KQ693_07850	COG0010	Belongs to the arginase family
KQ693_07870	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KQ693_07875	COG0511	ligase activity, forming carbon-carbon bonds
KQ693_07880	COG0439	Biotin carboxylase
KQ693_07890	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KQ693_07895	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KQ693_07900	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
KQ693_07910	COG2181	nitrate reductase activity
KQ693_07910	COG0247	lactate metabolic process
KQ693_07920	COG0861	Integral membrane protein TerC family
KQ693_07935	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KQ693_07940	COG0438	transferase activity, transferring glycosyl groups
KQ693_07985	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
KQ693_07990	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KQ693_08000	COG3383	formate dehydrogenase (NAD+) activity
KQ693_08000	COG0243	molybdopterin cofactor binding
KQ693_08005	COG0437	4 iron, 4 sulfur cluster binding
KQ693_08020	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KQ693_08025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KQ693_08050	COG3845	ABC transporter
KQ693_08055	COG4603	Belongs to the binding-protein-dependent transport system permease family
KQ693_08060	COG1079	Belongs to the binding-protein-dependent transport system permease family
KQ693_08070	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KQ693_08075	COG0494	nUDIX hydrolase
KQ693_08085	COG0138	bifunctional purine biosynthesis protein purh
KQ693_08095	COG2337	Toxic component of a toxin-antitoxin (TA) module
KQ693_08100	COG3239	Fatty acid desaturase
KQ693_08110	COG1490	D-aminoacyl-tRNA deacylase activity
KQ693_08115	COG1307	EDD domain protein, DegV family
KQ693_08120	COG1307	EDD domain protein, DegV family
KQ693_08125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KQ693_08140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ693_08150	COG1012	belongs to the aldehyde dehydrogenase family
KQ693_08155	COG2368	4-hydroxyphenylacetate
KQ693_08160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ693_08195	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KQ693_08205	COG1492	cobalamin metabolic process
KQ693_08210	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KQ693_08220	COG0574	Belongs to the PEP-utilizing enzyme family
KQ693_08220	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KQ693_08235	COG3842	ATPase activity
KQ693_08240	COG3290	protein histidine kinase activity
KQ693_08245	COG4565	transcriptional regulatory protein
KQ693_08255	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
KQ693_08280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQ693_08295	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
KQ693_08300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQ693_08305	COG0601	transmembrane transport
KQ693_08315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KQ693_08325	COG2226	methyltransferase
KQ693_08335	COG0601	transmembrane transport
KQ693_08340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQ693_08345	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
KQ693_08350	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KQ693_08355	COG2188	Transcriptional regulator
KQ693_08360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KQ693_08365	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
KQ693_08370	COG1472	Belongs to the glycosyl hydrolase 3 family
KQ693_08380	COG1175	transmembrane transport
KQ693_08385	COG0395	ABC-type sugar transport system, permease component
KQ693_08390	COG0019	diaminopimelate decarboxylase activity
KQ693_08400	COG2205	protein histidine kinase activity
KQ693_08430	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KQ693_08445	COG0589	response to stress
KQ693_08465	COG1993	acr, cog1993
KQ693_08480	COG1193	negative regulation of DNA recombination
KQ693_08485	COG1193	negative regulation of DNA recombination
KQ693_08495	COG2205	protein histidine kinase activity
KQ693_08505	COG2010	Cytochrome c
KQ693_08510	COG1914	H( )-stimulated, divalent metal cation uptake system
KQ693_08530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KQ693_08535	COG0642	Histidine kinase
KQ693_08545	COG0671	phosphoesterase, PA-phosphatase related
KQ693_08560	COG2323	membrane
KQ693_08575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KQ693_08585	COG3258	Cytochrome c
KQ693_08590	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KQ693_08595	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KQ693_08600	COG0363	glucosamine-6-phosphate deaminase activity
KQ693_08615	COG0730	response to heat
KQ693_08660	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
KQ693_08660	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
KQ693_08680	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KQ693_08700	COG0588	phosphoglycerate mutase activity
KQ693_08710	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KQ693_08715	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
KQ693_08725	COG1797	cobyrinic acid a,c-diamide synthase activity
KQ693_08730	COG2046	Belongs to the sulfate adenylyltransferase family
KQ693_08735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KQ693_08735	COG1648	precorrin-2 dehydrogenase activity
KQ693_08740	COG0730	response to heat
KQ693_08745	COG0175	sulfate reduction
KQ693_08750	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KQ693_08750	COG1648	precorrin-2 dehydrogenase activity
KQ693_08755	COG1587	Uroporphyrinogen-III synthase
KQ693_08760	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQ693_08765	COG0352	thiamine-phosphate diphosphorylase activity
KQ693_08770	COG2104	thiamine diphosphate biosynthetic process
KQ693_08775	COG2022	thiamine diphosphate biosynthetic process
KQ693_08780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KQ693_08780	COG2022	thiamine diphosphate biosynthetic process
KQ693_08785	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KQ693_08800	COG0351	phosphomethylpyrimidine kinase
KQ693_08805	COG1028	Short-chain dehydrogenase reductase Sdr
KQ693_08810	COG0318	PFAM AMP-dependent synthetase and ligase
KQ693_08815	COG1012	belongs to the aldehyde dehydrogenase family
KQ693_08815	COG2030	dehydratase
KQ693_08820	COG1960	acyl-CoA dehydrogenase activity
KQ693_08825	COG1309	transcriptional regulator
KQ693_08830	COG1980	fructose-bisphosphate aldolase activity
KQ693_08860	COG0410	ABC transporter
KQ693_08875	COG0559	Belongs to the binding-protein-dependent transport system permease family
KQ693_08885	COG1028	Short-chain dehydrogenase reductase Sdr
KQ693_08890	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KQ693_08895	COG0789	Transcriptional regulator
KQ693_08900	COG1960	acyl-CoA dehydrogenase activity
KQ693_08945	COG2186	Transcriptional regulator
KQ693_08960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQ693_08975	COG0395	ABC-type sugar transport system, permease component
KQ693_08980	COG1175	transmembrane transport
KQ693_08990	COG1609	Transcriptional regulator
KQ693_09000	COG1607	acyl-coa hydrolase
KQ693_09005	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KQ693_09020	COG1378	Sugar-specific transcriptional regulator TrmB
KQ693_09025	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KQ693_09030	COG0022	dehydrogenase e1 component
KQ693_09040	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
KQ693_09050	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KQ693_09050	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
KQ693_09060	COG1349	DNA-binding transcription factor activity
KQ693_09065	COG0434	BtpA family
KQ693_09070	COG1070	Carbohydrate kinase
KQ693_09080	COG0395	ABC-type sugar transport system, permease component
KQ693_09090	COG1175	transmembrane transport
KQ693_09095	COG3842	ATPase activity
KQ693_09100	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KQ693_09110	COG1178	ABC-type Fe3 transport system permease component
KQ693_09115	COG1177	transmembrane transport
KQ693_09135	COG0395	ABC-type sugar transport system, permease component
KQ693_09140	COG1175	transmembrane transport
KQ693_09165	COG1785	Belongs to the alkaline phosphatase family
KQ693_09170	COG1126	abc transporter atp-binding protein
KQ693_09175	COG0765	amino acid transport
KQ693_09180	COG4597	amino acid ABC transporter
KQ693_09185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ693_09190	COG0829	nickel cation binding
KQ693_09195	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KQ693_09200	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
KQ693_09205	COG0804	urea catabolic process
KQ693_09210	COG0832	Belongs to the urease beta subunit family
KQ693_09210	COG0831	urea catabolic process
KQ693_09220	COG0831	urea catabolic process
KQ693_09265	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KQ693_09325	COG4974	Belongs to the 'phage' integrase family
KQ693_09340	COG3396	Phenylacetate-CoA oxygenase
KQ693_09350	COG3396	Phenylacetate-CoA oxygenase
KQ693_09360	COG1012	belongs to the aldehyde dehydrogenase family
KQ693_09360	COG2030	dehydratase
KQ693_09365	COG1733	regulation of RNA biosynthetic process
KQ693_09370	COG2193	ferroxidase activity
KQ693_09380	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KQ693_09405	COG1404	Belongs to the peptidase S8 family
KQ693_09420	COG1331	Highly conserved protein containing a thioredoxin domain
KQ693_09425	COG0183	Belongs to the thiolase family
KQ693_09430	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
KQ693_09435	COG0477	Major facilitator Superfamily
KQ693_09445	COG1960	acyl-CoA dehydrogenase activity
KQ693_09450	COG2414	aldehyde ferredoxin oxidoreductase
KQ693_09460	COG3153	acetyltransferase
KQ693_09460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KQ693_09465	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KQ693_09470	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KQ693_09475	COG1177	transmembrane transport
KQ693_09480	COG1176	ABC-type spermidine putrescine transport system, permease component I
KQ693_09485	COG3842	ATPase activity
KQ693_09490	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KQ693_09495	COG1012	belongs to the aldehyde dehydrogenase family
KQ693_09500	COG1177	transmembrane transport
KQ693_09505	COG1176	ABC-type spermidine putrescine transport system, permease component I
KQ693_09510	COG3842	ATPase activity
KQ693_09515	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
KQ693_09520	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KQ693_09535	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
KQ693_09540	COG0803	Belongs to the bacterial solute-binding protein 9 family
KQ693_09545	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KQ693_09550	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KQ693_09560	COG3383	formate dehydrogenase (NAD+) activity
KQ693_09565	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KQ693_09575	COG5002	protein histidine kinase activity
KQ693_09580	COG1960	acyl-CoA dehydrogenase activity
KQ693_09585	COG2086	electron transfer activity
KQ693_09590	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KQ693_09600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KQ693_09615	COG1573	uracil-dna glycosylase
KQ693_09620	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
KQ693_09620	COG1796	DNA polymerase
KQ693_09635	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KQ693_09635	COG1013	pyruvate-flavodoxin oxidoreductase activity
KQ693_09635	COG0674	pyruvate-flavodoxin oxidoreductase activity
KQ693_09635	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KQ693_09650	COG2873	o-acetylhomoserine
KQ693_09660	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KQ693_09665	COG0215	cysteine-tRNA ligase activity
KQ693_09670	COG1960	acyl-CoA dehydrogenase activity
KQ693_09675	COG0183	Belongs to the thiolase family
KQ693_09680	COG1024	Enoyl-CoA hydratase
KQ693_09680	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQ693_09705	COG1215	transferase activity, transferring glycosyl groups
KQ693_09720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KQ693_09720	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KQ693_09725	COG1811	Na channel or pump
KQ693_09730	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KQ693_09735	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KQ693_09740	COG4948	Mandelate Racemase Muconate Lactonizing
KQ693_09750	COG0402	S-adenosylhomocysteine deaminase activity
KQ693_09775	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KQ693_09780	COG0742	ribosomal rna small subunit methyltransferase
KQ693_09795	COG2873	o-acetylhomoserine
KQ693_09800	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KQ693_09805	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KQ693_09810	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KQ693_09830	COG0149	triose-phosphate isomerase activity
KQ693_09835	COG0126	phosphoglycerate kinase activity
KQ693_09845	COG1268	BioY protein
KQ693_09855	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KQ693_09870	COG1196	nuclear chromosome segregation
KQ693_09880	COG0450	alkyl hydroperoxide reductase
KQ693_09890	COG2738	Putative neutral zinc metallopeptidase
KQ693_09895	COG2897	thiosulfate sulfurtransferase activity
KQ693_09900	COG1760	l-serine dehydratase
KQ693_09905	COG2197	response regulator
KQ693_09910	COG0335	large ribosomal subunit rRNA binding
KQ693_09915	COG0336	Belongs to the RNA methyltransferase TrmD family
KQ693_09920	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KQ693_09930	COG0228	four-way junction DNA binding
KQ693_09940	COG2239	Acts as a magnesium transporter
KQ693_09950	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KQ693_09965	COG1692	metallophosphoesterase
KQ693_09995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KQ693_10000	COG1410	methionine synthase
KQ693_10000	COG0646	methionine synthase
KQ693_10005	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
KQ693_10010	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KQ693_10015	COG0740	serine-type endopeptidase activity
KQ693_10020	COG0544	peptidyl-prolyl cis-trans isomerase activity
KQ693_10040	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KQ693_10045	COG3870	Protein conserved in bacteria
KQ693_10050	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
KQ693_10060	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KQ693_10070	COG1595	DNA-templated transcription, initiation
KQ693_10090	COG4475	Protein of unknown function (DUF436)
KQ693_10110	COG0651	ATP synthesis coupled electron transport
KQ693_10125	COG0651	ATP synthesis coupled electron transport
KQ693_10140	COG1970	mechanosensitive ion channel activity
KQ693_10145	COG3842	ATPase activity
KQ693_10150	COG0572	uridine kinase
KQ693_10170	COG2176	DNA-directed DNA polymerase activity
KQ693_10175	COG0154	amidase activity
KQ693_10180	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KQ693_10190	COG1435	thymidine kinase activity
KQ693_10195	COG0254	rRNA binding
KQ693_10440	COG5005	Phage virion morphogenesis
KQ693_10470	COG2001	Belongs to the MraZ family
KQ693_10475	COG0275	rRNA processing
KQ693_10490	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KQ693_10500	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KQ693_10505	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KQ693_10510	COG0772	Belongs to the SEDS family
KQ693_10515	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KQ693_10520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KQ693_10525	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KQ693_10545	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KQ693_10565	COG2391	methyltransferase activity
KQ693_10575	COG0243	molybdopterin cofactor binding
KQ693_10605	COG1028	Short-chain dehydrogenase reductase Sdr
KQ693_10620	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQ693_10640	COG1175	transmembrane transport
KQ693_10670	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KQ693_10675	COG2264	protein methyltransferase activity
KQ693_10685	COG0489	protein tyrosine kinase activity
KQ693_10700	COG0525	valine-tRNA ligase activity
KQ693_10710	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KQ693_10720	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KQ693_10725	COG0134	indole-3-glycerol-phosphate synthase activity
KQ693_10730	COG1752	Esterase of the alpha-beta hydrolase superfamily
KQ693_10740	COG1126	abc transporter atp-binding protein
KQ693_10750	COG2358	TRAP transporter, solute receptor (TAXI family
KQ693_10755	COG0765	amino acid transport
KQ693_10760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ693_10775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KQ693_10780	COG0569	domain protein
KQ693_10785	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KQ693_10795	COG2313	pseudouridylate synthase activity
KQ693_10805	COG3001	Fructosamine kinase
KQ693_10810	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KQ693_10815	COG4585	Histidine kinase
KQ693_10840	COG0012	GTP binding
KQ693_10845	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
KQ693_10855	COG0424	maF-like protein
KQ693_10870	COG0768	penicillin binding
KQ693_10880	COG2322	membrane
KQ693_10905	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KQ693_10910	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KQ693_10920	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
KQ693_10935	COG3842	ATPase activity
KQ693_10945	COG0124	histidyl-tRNA synthetase
KQ693_10955	COG0384	phenazine biosynthesis protein PhzF
KQ693_10960	COG0561	phosphatase activity
KQ693_10975	COG0745	RESPONSE REGULATOR receiver
KQ693_10985	COG0017	Asparaginyl-tRNA synthetase
KQ693_10990	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KQ693_11000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KQ693_11005	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
KQ693_11010	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KQ693_11020	COG0640	Transcriptional regulator
KQ693_11025	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
KQ693_11030	COG0739	heme binding
KQ693_11035	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KQ693_11040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KQ693_11045	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KQ693_11055	COG0006	proline dipeptidase activity
KQ693_11060	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KQ693_11065	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
KQ693_11075	COG1994	Peptidase M50
KQ693_11085	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KQ693_11085	COG0617	tRNA 3'-terminal CCA addition
KQ693_11085	COG0517	IMP dehydrogenase activity
KQ693_11105	COG0052	Belongs to the universal ribosomal protein uS2 family
KQ693_11110	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KQ693_11115	COG0528	UMP kinase activity
KQ693_11120	COG0233	cytoplasmic translational termination
KQ693_11125	COG4589	Belongs to the CDS family
KQ693_11130	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KQ693_11135	COG0750	zinc metalloprotease
KQ693_11150	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KQ693_11155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KQ693_11160	COG2359	stage V sporulation protein S
KQ693_11170	COG2137	regulation of response to DNA damage stimulus
KQ693_11190	COG2766	serine protein kinase
KQ693_11195	COG2718	Belongs to the UPF0229 family
KQ693_11200	COG2719	SpoVR family
KQ693_11205	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KQ693_11210	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KQ693_11225	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KQ693_11230	COG0730	response to heat
KQ693_11245	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KQ693_11250	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KQ693_11255	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
KQ693_11260	COG3706	GGDEF domain
KQ693_11275	COG2151	metal-sulfur cluster biosynthetic enzyme
KQ693_11315	COG2181	nitrate reductase activity
KQ693_11330	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
KQ693_11345	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQ693_11365	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KQ693_11380	COG0535	radical SAM domain protein
KQ693_11385	COG2010	Cytochrome c
KQ693_11395	COG3256	nitric oxide reductase
KQ693_11400	COG2010	Cytochrome c
KQ693_11430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KQ693_11435	COG3191	aminopeptidase activity
KQ693_11445	COG1063	alcohol dehydrogenase
KQ693_11450	COG0714	Associated with various cellular activities
KQ693_11465	COG2304	oxidoreductase activity
KQ693_11485	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KQ693_11490	COG2884	Cell division ATP-binding protein ftsE
KQ693_11495	COG0793	Belongs to the peptidase S41A family
KQ693_11500	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ693_11500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ693_11505	COG2361	Protein of unknown function DUF86
KQ693_11515	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KQ693_11520	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KQ693_11530	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
KQ693_11535	COG0159	tryptophan synthase activity
KQ693_11540	COG0133	tryptophan synthase activity
KQ693_11545	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
KQ693_11555	COG1744	ABC transporter substrate-binding protein PnrA-like
KQ693_11560	COG3845	ABC transporter
KQ693_11585	COG0745	RESPONSE REGULATOR receiver
KQ693_11590	COG1605	Chorismate mutase
KQ693_11590	COG0077	Prephenate dehydratase
KQ693_11595	COG0517	IMP dehydrogenase activity
KQ693_11610	COG1674	ftsk spoiiie
KQ693_11615	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KQ693_11620	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KQ693_11625	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KQ693_11630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KQ693_11630	COG4651	solute:proton antiporter activity
KQ693_11635	COG0217	transcriptional regulatory protein
KQ693_11640	COG0653	protein targeting
KQ693_11645	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KQ693_11675	COG1960	acyl-CoA dehydrogenase activity
KQ693_11685	COG0312	modulator of DNA gyrase
KQ693_11690	COG0312	modulator of DNA gyrase
KQ693_11710	COG0730	response to heat
KQ693_11735	COG0167	dihydroorotate dehydrogenase activity
KQ693_11745	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KQ693_11785	COG0746	molybdenum cofactor guanylyltransferase activity
KQ693_11800	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KQ693_11820	COG0538	isocitrate dehydrogenase activity
KQ693_11825	COG0557	exoribonuclease II activity
KQ693_11855	COG0585	pseudouridine synthase activity
KQ693_11875	COG2050	protein possibly involved in aromatic compounds catabolism
KQ693_11885	COG0322	excinuclease ABC activity
KQ693_11895	COG0018	arginyl-trna synthetase
KQ693_11900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KQ693_11905	COG1428	Deoxynucleoside kinase
KQ693_11910	COG1428	Deoxynucleoside kinase
KQ693_11915	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KQ693_11920	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
KQ693_11925	COG0107	imidazoleglycerol-phosphate synthase activity
KQ693_11930	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KQ693_11930	COG0140	phosphoribosyl-ATP diphosphatase activity
KQ693_11940	COG1494	fructose-1,6-bisphosphatase
KQ693_11965	COG0395	ABC-type sugar transport system, permease component
KQ693_11970	COG1175	transmembrane transport
KQ693_11995	COG0084	hydrolase, TatD family'
KQ693_12000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KQ693_12010	COG0017	Asparaginyl-tRNA synthetase
KQ693_12015	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KQ693_12030	COG2009	succinate dehydrogenase
KQ693_12035	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KQ693_12065	COG0318	PFAM AMP-dependent synthetase and ligase
KQ693_12070	COG1104	cysteine desulfurase activity
KQ693_12075	COG1959	2 iron, 2 sulfur cluster binding
KQ693_12080	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KQ693_12090	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KQ693_12095	COG2255	four-way junction helicase activity
KQ693_12115	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KQ693_12125	COG1085	galactose-1-phosphate uridylyltransferase
KQ693_12130	COG3345	alpha-galactosidase
KQ693_12135	COG2211	Major facilitator Superfamily
KQ693_12140	COG3250	beta-galactosidase activity
KQ693_12155	COG2211	Major facilitator Superfamily
KQ693_12165	COG1181	Belongs to the D-alanine--D-alanine ligase family
KQ693_12170	COG0193	aminoacyl-tRNA hydrolase activity
KQ693_12175	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KQ693_12180	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KQ693_12185	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KQ693_12190	COG1854	S-ribosylhomocysteine lyase activity
KQ693_12195	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KQ693_12195	COG0519	Catalyzes the synthesis of GMP from XMP
KQ693_12200	COG4636	protein conserved in cyanobacteria
KQ693_12205	COG4274	PFAM GYD family protein
KQ693_12220	COG0328	RNA-DNA hybrid ribonuclease activity
KQ693_12225	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KQ693_12260	COG0037	tRNA processing
KQ693_12260	COG0590	tRNA wobble adenosine to inosine editing
KQ693_12290	COG1877	trehalose-phosphatase activity
KQ693_12295	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KQ693_12300	COG0366	Alpha amylase catalytic
KQ693_12310	COG2226	methyltransferase
KQ693_12315	COG0693	protein deglycase activity
KQ693_12325	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KQ693_12335	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KQ693_12340	COG0460	homoserine dehydrogenase
KQ693_12345	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KQ693_12380	COG0037	tRNA processing
KQ693_12385	COG2104	thiamine diphosphate biosynthetic process
KQ693_12390	COG0123	including yeast histone deacetylase and acetoin utilization protein
KQ693_12395	COG0517	IMP dehydrogenase activity
KQ693_12405	COG0444	Belongs to the ABC transporter superfamily
KQ693_12410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQ693_12415	COG0601	transmembrane transport
KQ693_12420	COG0747	negative chemotaxis
KQ693_12425	COG0604	alcohol dehydrogenase
KQ693_12430	COG0492	ferredoxin-NADP+ reductase activity
KQ693_12460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ693_12465	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KQ693_12470	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KQ693_12490	COG2070	2-Nitropropane dioxygenase
KQ693_12510	COG0745	RESPONSE REGULATOR receiver
KQ693_12515	COG5002	protein histidine kinase activity
KQ693_12535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KQ693_12540	COG0572	uridine kinase
KQ693_12545	COG0464	growth
KQ693_12555	COG1850	ribulose-bisphosphate carboxylase activity
KQ693_12565	COG0583	DNA-binding transcription factor activity
KQ693_12600	COG2045	Belongs to the ComB family
KQ693_12620	COG0513	Belongs to the DEAD box helicase family
KQ693_12625	COG0303	'Molybdopterin
KQ693_12645	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KQ693_12650	COG0442	prolyl-tRNA aminoacylation
KQ693_12660	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
KQ693_12670	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KQ693_12685	COG1028	Short-chain dehydrogenase reductase Sdr
KQ693_12700	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KQ693_12705	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KQ693_12715	COG1482	cell wall glycoprotein biosynthetic process
KQ693_12725	COG1515	deoxyribonuclease V activity
KQ693_12735	COG0776	regulation of translation
KQ693_12740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KQ693_12745	COG0443	Heat shock 70 kDa protein
KQ693_12750	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KQ693_12755	COG0484	heat shock protein binding
KQ693_12760	COG0789	Transcriptional regulator
KQ693_12855	COG1192	Involved in chromosome partitioning
KQ693_12880	COG4974	Belongs to the 'phage' integrase family