locus-tag	class	description
TthHC11_00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
TthHC11_00020	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
TthHC11_00030	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
TthHC11_00040	ENOG4105CA9	Pyruvate kinase
TthHC11_00060	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
TthHC11_00070	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
TthHC11_00090	ENOG41087YS	Phage shock protein A
TthHC11_00120	ENOG4105CVJ	phosphoglycerate mutase
TthHC11_00130	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
TthHC11_00140	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TthHC11_00150	ENOG4105CZX	twitching motility protein
TthHC11_00160	ENOG4107QHF	type ii secretion system protein e
TthHC11_00170	ENOG4108WJV	had superfamily (subfamily IIIa) phosphatase
TthHC11_00180	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
TthHC11_00190	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
TthHC11_00210	ENOG4107T3P	ABC, transporter
TthHC11_00240	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
TthHC11_00260	ENOG4105CSH	Transporter
TthHC11_00280	ENOG4105C2X	Arabinose 5-phosphate isomerase
TthHC11_00290	ENOG41082T9	Membrane
TthHC11_00300	ENOG4105C6T	cysteine synthase
TthHC11_00310	ENOG4108YZY	peptidylprolyl cis-trans isomerase
TthHC11_00320	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
TthHC11_00340	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
TthHC11_00350	ENOG4105CHM	Aminotransferase
TthHC11_00360	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
TthHC11_00410	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
TthHC11_00420	ENOG4105WMR	Protein CrcB homolog
TthHC11_00430	ENOG4105KJJ	Uncharacterized ACR, COG1993
TthHC11_00470	ENOG4107RVV	histidinol phosphate phosphatase, hisj family
TthHC11_00500	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
TthHC11_00510	ENOG4105SYT	Methylenetetrahydrofolate reductase
TthHC11_00540	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
TthHC11_00550	ENOG4105C8B	TIGR00159 family
TthHC11_00570	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
TthHC11_00580	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
TthHC11_00590	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
TthHC11_00600	ENOG4105CHW	UPF0052 protein
TthHC11_00660	ENOG4105BZ9	Cytochrome C oxidase, subunit I
TthHC11_00670	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
TthHC11_00680	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
TthHC11_00710	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
TthHC11_00720	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
TthHC11_00730	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
TthHC11_00780	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
TthHC11_00800	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TthHC11_00820	ENOG41080TK	Universal stress protein
TthHC11_00850	ENOG4105PAD	Hydrolase
TthHC11_00860	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
TthHC11_00870	ENOG4108UKI	Enoyl-CoA hydratase
TthHC11_00880	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
TthHC11_00890	ENOG4105C7S	Dehydrogenase
TthHC11_00940	ENOG4105CDH	Citrulline--aspartate ligase
TthHC11_00950	ENOG4105CH7	arginosuccinase
TthHC11_00980	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
TthHC11_01000	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
TthHC11_01010	ENOG4105C89	phosphohexose isomerase
TthHC11_01040	ENOG4108RWN	rrna methyltransferase
TthHC11_01050	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
TthHC11_01060	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
TthHC11_01070	ENOG4105CTD	carboxy-peptidase
TthHC11_01100	ENOG4108DBC	nitroreductase
TthHC11_01110	ENOG4105K4H	Nlp p60 protein
TthHC11_01130	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
TthHC11_01150	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
TthHC11_01160	ENOG4105E2Z	phosphate ABC transporter (Permease
TthHC11_01170	ENOG4105C8U	phosphate abc transporter
TthHC11_01190	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
TthHC11_01210	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
TthHC11_01220	ENOG4105G5W	regulator Fur family
TthHC11_01250	ENOG4105CY0	Metallo-Beta-Lactamase
TthHC11_01260	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TthHC11_01270	ENOG4105WDJ	50S ribosomal protein L33
TthHC11_01280	ENOG410683Z	Preprotein translocase SecE subunit
TthHC11_01290	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
TthHC11_01300	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
TthHC11_01310	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
TthHC11_01340	ENOG41082AW	Binds together with S18 to 16S ribosomal RNA (By similarity)
TthHC11_01350	ENOG4105Z8H	single-stranded DNA-binding protein
TthHC11_01360	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
TthHC11_01370	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
TthHC11_01380	ENOG4105DMF	Dehydrogenase
TthHC11_01390	ENOG4105E1F	short-chain dehydrogenase reductase
TthHC11_01400	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
TthHC11_01410	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
TthHC11_01490	ENOG4107QN2	dihydrolipoyl dehydrogenase
TthHC11_01520	ENOG4105ZVY	2-oxoisovalerate dehydrogenase, E1 component beta subunit
TthHC11_01530	ENOG4105CPP	Dehydrogenase, E1 component
TthHC11_01540	ENOG4107SUU	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
TthHC11_01550	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
TthHC11_01580	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
TthHC11_01590	ENOG4107V9E	glucose-1-phosphate thymidylyltransferase
TthHC11_01600	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TthHC11_01610	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
TthHC11_01630	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
TthHC11_01640	ENOG4105FE9	pseudouridine synthase
TthHC11_01660	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
TthHC11_01670	ENOG4105DCF	alanine dehydrogenase
TthHC11_01690	ENOG4105DP4	dak2 domain fusion protein ylov
TthHC11_01710	ENOG41069ER	domain protein
TthHC11_01720	ENOG4105D60	lipoprotein releasing system transmembrane protein
TthHC11_01730	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
TthHC11_01740	ENOG4108VZM	50s ribosomal protein L10
TthHC11_01750	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
TthHC11_01760	ENOG4105W8H	transhydrogenase (subunit alpha
TthHC11_01770	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
TthHC11_01790	ENOG4108594	Permease of the drug metabolite transporter
TthHC11_01820	ENOG4105C0P	Mg chelatase subunit ChlI
TthHC11_01830	ENOG4108J2R	molybdopterin oxidoreductase
TthHC11_01840	ENOG4105EBR	Carboxylesterase
TthHC11_01850	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TthHC11_01870	ENOG4105CH5	extracellular solute-binding protein, family 7
TthHC11_01880	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
TthHC11_01900	ENOG4105C57	major facilitator superfamily
TthHC11_01920	ENOG4105EEI	dihydropteroate synthase
TthHC11_01930	ENOG4105KRF	dihydroneopterin aldolase
TthHC11_01950	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
TthHC11_01960	ENOG4108ZF3	Phosphatase
TthHC11_01970	ENOG4107RSM	transcriptional regulator
TthHC11_01980	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
TthHC11_01990	ENOG4107QSN	dihydrolipoamide acetyltransferase
TthHC11_02030	ENOG4105C0B	DNA polymerase III (alpha subunit)
TthHC11_02060	ENOG4108Z4U	Ferredoxin
TthHC11_02090	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TthHC11_02100	ENOG4105C5R	Aminotransferase
TthHC11_02110	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
TthHC11_02120	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
TthHC11_02130	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
TthHC11_02160	ENOG4107Z3H	Transcriptional regulator, TetR family
TthHC11_02200	ENOG4105K8N	protein family UPF0079, ATPase
TthHC11_02210	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
TthHC11_02220	ENOG4105C8T	Leucyl-tRNA synthetase
TthHC11_02270	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
TthHC11_02310	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
TthHC11_02320	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
TthHC11_02360	ENOG4108VAU	general secretion pathway protein G
TthHC11_02420	ENOG4107QHF	type ii secretion system protein e
TthHC11_02430	ENOG4105D7Q	type ii secretion system
TthHC11_02450	ENOG4105I08	Pseudouridine synthase
TthHC11_02470	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TthHC11_02480	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TthHC11_02490	ENOG4105BZU	Histidine kinase
TthHC11_02500	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
TthHC11_02510	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
TthHC11_02530	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TthHC11_02550	ENOG4107QPV	Serine Threonine protein kinase
TthHC11_02560	ENOG4105KME	endoribonuclease L-psp
TthHC11_02590	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
TthHC11_02600	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
TthHC11_02630	ENOG4105DHP	deoxycytidine triphosphate deaminase
TthHC11_02640	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
TthHC11_02650	ENOG4107ZZY	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
TthHC11_02660	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
TthHC11_02670	ENOG4105CM2	brancheD-chain amino acid aminotransferase
TthHC11_02680	ENOG4105DND	Transcriptional regulator
TthHC11_02690	ENOG4105WEF	catalase
TthHC11_02730	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
TthHC11_02740	ENOG4108UW5	maltose o-acetyltransferase
TthHC11_02750	ENOG4105SFS	phosphoesterase RecJ domain protein
TthHC11_02770	ENOG4105E3H	phosphoglycerate mutase
TthHC11_02780	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
TthHC11_02830	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
TthHC11_02840	ENOG4105C1J	atp-dependent rna helicase
TthHC11_02890	ENOG4108P8R	
TthHC11_02940	ENOG4107QMH	DNA methylase
TthHC11_02980	ENOG4105VTR	Integrase
TthHC11_02990	ENOG4105CV1	Transketolase (EC 2.2.1.1)
TthHC11_03070	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
TthHC11_03080	ENOG4105C0H	protease
TthHC11_03090	ENOG4105C75	arginyL-tRNA synthetase
TthHC11_03100	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TthHC11_03110	ENOG4107WFQ	NADH-quinone oxidoreductase, chain M
TthHC11_03120	ENOG4105D65	subunit l
TthHC11_03130	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TthHC11_03140	ENOG41087XN	oxidoreductase
TthHC11_03150	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TthHC11_03160	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
TthHC11_03170	ENOG4108IEH	NADH dehydrogenase subunit g
TthHC11_03180	ENOG4107EEP	NADH dehydrogenase (quinone) (EC 1.6.99.5)
TthHC11_03190	ENOG4105GKE	subunit e
TthHC11_03200	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TthHC11_03210	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TthHC11_03220	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TthHC11_03230	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TthHC11_03240	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
TthHC11_03260	ENOG4105VIZ	double-strand break repair protein
TthHC11_03300	ENOG4105ECY	inositol monophosphatase
TthHC11_03310	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
TthHC11_03320	ENOG4107S45	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TthHC11_03330	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
TthHC11_03350	ENOG41073R8	VanW family
TthHC11_03360	ENOG4105CDA	abc transporter atp-binding protein
TthHC11_03420	ENOG4105EU8	FAD linked oxidase domain protein
TthHC11_03440	ENOG4105C25	Primosomal protein n'
TthHC11_03490	ENOG4108ZAF	Molybdopterin
TthHC11_03500	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
TthHC11_03520	ENOG4105BZU	Histidine kinase
TthHC11_03530	ENOG4105CB5	ATP-dependent DNA helicase recG
TthHC11_03540	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
TthHC11_03560	ENOG4105DGU	Histone deacetylase
TthHC11_03590	ENOG4105CBD	Diacylglycerol kinase
TthHC11_03600	ENOG41062MS	nucleotidyltransferase substrate binding protein
TthHC11_03620	ENOG4105CHM	Aminotransferase
TthHC11_03650	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
TthHC11_03660	ENOG4106633	50S ribosomal protein l28
TthHC11_03680	ENOG4105CQB	FAD linked oxidase domain protein
TthHC11_03770	ENOG4105ZEG	Suppressor protein
TthHC11_03840	ENOG4105CPC	Aldo Keto reductase
TthHC11_03910	ENOG4105DAN	ATP-dependent protease
TthHC11_03920	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
TthHC11_03950	ENOG4108ZHD	aig2 family
TthHC11_03960	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
TthHC11_03980	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
TthHC11_03990	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
TthHC11_04020	ENOG4105EAH	synthase
TthHC11_04040	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TthHC11_04050	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
TthHC11_04060	ENOG4105C3M	thioredoxin reductase
TthHC11_04080	ENOG410850P	UPF0102 protein
TthHC11_04090	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
TthHC11_04120	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
TthHC11_04130	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
TthHC11_04210	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
TthHC11_04220	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
TthHC11_04230	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
TthHC11_04240	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
TthHC11_04250	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
TthHC11_04360	ENOG4105E2A	Dehydrogenase
TthHC11_04420	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
TthHC11_04430	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
TthHC11_04440	ENOG4105C34	Pseudouridine synthase
TthHC11_04480	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
TthHC11_04490	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
TthHC11_04500	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
TthHC11_04510	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
TthHC11_04520	ENOG4105CHR	reductase
TthHC11_04530	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
TthHC11_04540	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
TthHC11_04550	ENOG41067VY	50S ribosomal protein L32
TthHC11_04620	ENOG4105CHR	reductase
TthHC11_04630	ENOG4108TVJ	Nitroreductase
TthHC11_04670	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TthHC11_04680	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
TthHC11_04690	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
TthHC11_04700	ENOG4107Y7Q	pfkb domain protein
TthHC11_04710	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TthHC11_04750	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
TthHC11_04770	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
TthHC11_04780	ENOG4108IUZ	ABC transporter
TthHC11_04810	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
TthHC11_04820	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
TthHC11_04830	ENOG4107K5T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
TthHC11_04840	ENOG4105C0Z	ABC transporter
TthHC11_04850	ENOG4108IQE	Amp-dependent synthetase and ligase
TthHC11_04860	ENOG4105C32	Amino acid ABC transporter (Permease)
TthHC11_04870	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
TthHC11_04890	ENOG4108IV0	ABC, transporter
TthHC11_04900	ENOG4105DIK	(ABC) transporter
TthHC11_04910	ENOG4105CC5	ABC transporter
TthHC11_04930	ENOG4107QI6	Cysteine desulfurase
TthHC11_04940	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
TthHC11_04950	ENOG4105CAT	Cytidine monophosphate kinase
TthHC11_04980	ENOG4105CHR	reductase
TthHC11_05020	ENOG4105CAY	ferredoxin--nadp reductase
TthHC11_05040	ENOG4107QRA	Extracellular solute-binding protein, family 5
TthHC11_05060	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TthHC11_05090	ENOG41080XP	Cbs domain
TthHC11_05100	ENOG4105DGU	Histone deacetylase
TthHC11_05110	ENOG4106C07	ThiamineS Protein
TthHC11_05120	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
TthHC11_05130	ENOG4105CG3	alpha amylase, catalytic region
TthHC11_05150	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
TthHC11_05170	ENOG4105CG3	alpha amylase, catalytic region
TthHC11_05180	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TthHC11_05190	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TthHC11_05200	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
TthHC11_05220	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
TthHC11_05270	ENOG4105D6E	homoserine dehydrogenase
TthHC11_05340	ENOG4106YGA	NADH dehydrogenase (quinone)
TthHC11_05360	ENOG4105CSA	Coproporphyrinogen iii oxidase
TthHC11_05400	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
TthHC11_05410	ENOG4105CQB	FAD linked oxidase domain protein
TthHC11_05420	ENOG4105CQB	FAD linked oxidase domain protein
TthHC11_05430	ENOG4107R9S	Malate synthase
TthHC11_05440	ENOG4107HP6	Transcriptional regulator
TthHC11_05450	ENOG4105KNI	merR family transcriptional Regulator
TthHC11_05460	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TthHC11_05470	ENOG4108Z7R	Chaperone CsaA
TthHC11_05480	ENOG4105DZS	Phenylacetate-CoA ligase
TthHC11_05500	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
TthHC11_05510	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
TthHC11_05550	ENOG4107TS3	membrane protein, TerC
TthHC11_05560	ENOG4105VG1	fes assembly suf system protein
TthHC11_05570	ENOG4107R1I	NAD-dependent malic enzyme
TthHC11_05600	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
TthHC11_05610	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
TthHC11_05620	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TthHC11_05630	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TthHC11_05640	ENOG4105DTN	riboflavin biosynthesis protein ribF
TthHC11_05690	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TthHC11_05700	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
TthHC11_05710	ENOG4105CFH	Aspartokinase
TthHC11_05720	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
TthHC11_05730	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
TthHC11_05740	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
TthHC11_05750	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
TthHC11_05760	ENOG4108JVH	Protein of unknown function DUF43
TthHC11_05770	ENOG4105CTP	PilT protein domain protein
TthHC11_05780	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
TthHC11_05800	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
TthHC11_05860	ENOG4105CX6	glutaminyL-tRNA synthetase
TthHC11_05880	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
TthHC11_05890	ENOG410868C	50s ribosomal protein l35
TthHC11_05900	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
TthHC11_05920	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
TthHC11_05930	ENOG41080X4	futalosine nucleosidase
TthHC11_05940	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
TthHC11_05950	ENOG4105C9Q	fumarate hydratase class II
TthHC11_05990	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
TthHC11_06000	ENOG4105DFA	alanine racemase domain protein
TthHC11_06030	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
TthHC11_06040	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
TthHC11_06070	ENOG4105CPQ	Dehydrogenase
TthHC11_06100	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
TthHC11_06110	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
TthHC11_06120	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
TthHC11_06160	ENOG4105DBI	uridine monophosphokinase
TthHC11_06170	ENOG4108IJ9	(ABC) transporter
TthHC11_06200	ENOG4108UIC	UPF0340 protein
TthHC11_06220	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
TthHC11_06240	ENOG4105C0Z	ABC transporter
TthHC11_06250	ENOG4108IV0	ABC, transporter
TthHC11_06270	ENOG4105CP9	extracellular ligand-binding receptor
TthHC11_06320	ENOG4105CH5	extracellular solute-binding protein, family 7
TthHC11_06330	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
TthHC11_06340	ENOG4105DSE	periplasmic solute binding protein
TthHC11_06370	ENOG4105C1Q	protoporphyrinogen oxidase
TthHC11_06380	ENOG4107QME	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
TthHC11_06390	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
TthHC11_06400	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
TthHC11_06430	ENOG4105CEY	Amp-dependent synthetase and ligase
TthHC11_06450	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
TthHC11_06460	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
TthHC11_06480	ENOG41066UU	tRNA (Adenine-N1-)-methyltransferase
TthHC11_06500	ENOG4105X0R	protein from nitrogen regulatory protein P-II
TthHC11_06510	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
TthHC11_06530	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
TthHC11_06540	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
TthHC11_06550	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
TthHC11_06560	ENOG4105DAP	Nicotinate phosphoribosyltransferase
TthHC11_06570	ENOG4105C3R	Methionine synthase
TthHC11_06590	ENOG4105CRQ	synthase (Component I)
TthHC11_06610	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
TthHC11_06640	ENOG4105D48	metallophosphoesterase
TthHC11_06650	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
TthHC11_06660	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
TthHC11_06830	ENOG4105CEC	DNA methylase N-4 N-6
TthHC11_06850	ENOG4105VTR	Integrase
TthHC11_06880	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
TthHC11_06890	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
TthHC11_07010	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
TthHC11_07090	ENOG4105D1F	ATP-binding protein
TthHC11_07110	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TthHC11_07180	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
TthHC11_07210	ENOG4107RIQ	Sulfate adenylate transferase
TthHC11_07220	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
TthHC11_07230	ENOG4107TSN	permease
TthHC11_07240	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
TthHC11_07250	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
TthHC11_07260	ENOG4105EXQ	uroporphyrinogen iii synthase hem4
TthHC11_07270	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
TthHC11_07290	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
TthHC11_07300	ENOG4108G2S	Thiamine biosynthesis protein thiS
TthHC11_07310	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
TthHC11_07330	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
TthHC11_07340	ENOG41079KZ	Major Facilitator Superfamily
TthHC11_07350	ENOG4105DWF	phosphomethylpyrimidine kinase
TthHC11_07430	ENOG4105E2R	ROK family
TthHC11_07440	ENOG4105CHU	acetyl-coa acetyltransferase
TthHC11_07470	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TthHC11_07490	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
TthHC11_07510	ENOG4105CHV	Transcription elongation factor NusA
TthHC11_07520	ENOG410836C	Required for maturation of 30S ribosomal subunits (By similarity)
TthHC11_07530	ENOG4105DR5	peptidase
TthHC11_07540	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
TthHC11_07550	ENOG4107YCR	Transcriptional regulator, ARSR family
TthHC11_07560	ENOG4105C59	p-type ATPase
TthHC11_07570	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
TthHC11_07580	ENOG4105C5S	asparaginyl-tRNA synthetase
TthHC11_07600	ENOG4107ZY0	Phenazine biosynthesis-like protein
TthHC11_07610	ENOG4105C9M	aspartyl-trna synthetase
TthHC11_07620	ENOG4105CUT	histidyl-tRNA synthetase
TthHC11_07650	ENOG4105E0C	molybdate abc transporter
TthHC11_07660	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
TthHC11_07670	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
TthHC11_07710	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
TthHC11_07720	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TthHC11_07740	ENOG4108KGH	TRANSCRIPTIONal
TthHC11_07750	ENOG4107QM5	aconitate hydratase
TthHC11_07780	ENOG4105BZS	acriflavin resistance protein
TthHC11_07840	ENOG4105KG3	cytidine deaminase
TthHC11_07860	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
TthHC11_07900	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
TthHC11_07920	ENOG4105EHG	Permease protein
TthHC11_07950	ENOG4105CHR	reductase
TthHC11_07970	ENOG4107S1E	Beta-lactamase
TthHC11_08040	ENOG4105BZU	Histidine kinase
TthHC11_08050	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
TthHC11_08060	ENOG4105F6J	Alpha beta hydrolase fold
TthHC11_08090	ENOG4105DWV	Homoserine O-trans-acetylase
TthHC11_08100	ENOG4108IQK	o-acetylhomoserine
TthHC11_08130	ENOG4107WTH	Galactitol-1-phosphate dehydrogenase
TthHC11_08160	ENOG4105CH5	extracellular solute-binding protein, family 7
TthHC11_08180	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
TthHC11_08200	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
TthHC11_08210	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
TthHC11_08220	ENOG4108IY8	ABC, transporter
TthHC11_08230	ENOG4105D2X	ABC transporter substrate-binding protein
TthHC11_08250	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
TthHC11_08270	ENOG4105CD3	dihydroorotase
TthHC11_08280	ENOG4105CXT	aspartate transcarbamylase
TthHC11_08290	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
TthHC11_08320	ENOG4105C5I	Dehydrogenase
TthHC11_08340	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
TthHC11_08360	ENOG4105C1G	acyl-Coa dehydrogenase
TthHC11_08370	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
TthHC11_08390	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
TthHC11_08400	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TthHC11_08440	ENOG4105CQB	FAD linked oxidase domain protein
TthHC11_08450	ENOG4105BZU	Histidine kinase
TthHC11_08470	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
TthHC11_08480	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
TthHC11_08490	ENOG4108YYC	ycei family
TthHC11_08500	ENOG4108XHF	Pfam:DUF178
TthHC11_08510	ENOG4105DVY	radical SAM domain protein
TthHC11_08540	ENOG4105ETE	Transcriptional regulator (LacI family
TthHC11_08550	ENOG41071YG	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
TthHC11_08560	ENOG4105ERH	Fumarylacetoacetate hydrolase
TthHC11_08580	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
TthHC11_08590	ENOG4107QNG	Phosphoribosylglycinamide synthetase
TthHC11_08600	ENOG4108IRC	dna polymerase iii
TthHC11_08620	ENOG4105BZU	Histidine kinase
TthHC11_08660	ENOG4107QN1	sodium solute
TthHC11_08680	ENOG4105CDY	transcriptional regulatory protein
TthHC11_08690	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
TthHC11_08700	ENOG4107ZQN	disulfide bond
TthHC11_08710	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
TthHC11_08720	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
TthHC11_08730	ENOG4105CNU	cell division protein FtsK
TthHC11_08760	ENOG4105W87	Cbs domain
TthHC11_08800	ENOG4108Z4T	Peptidase M50
TthHC11_08810	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
TthHC11_08830	ENOG41082J7	Rhodanese domain protein
TthHC11_08860	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
TthHC11_08880	ENOG4105ED1	spovr family
TthHC11_08890	ENOG4106AKX	UPF0229 protein
TthHC11_08900	ENOG4105CYN	Serine protein kinase
TthHC11_08970	ENOG4105MCT	stage V sporulation protein S
TthHC11_08980	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TthHC11_08990	ENOG4105II7	pyrroline-5-carboxylate reductase
TthHC11_09020	ENOG4105DZP	Membrane-associated zinc metalloprotease
TthHC11_09030	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
TthHC11_09040	ENOG4105KNE	Phosphatidate cytidylyltransferase
TthHC11_09050	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
TthHC11_09060	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
TthHC11_09070	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
TthHC11_09080	ENOG4105CE9	30S ribosomal protein S2
TthHC11_09090	ENOG4108FPN	Integrase
TthHC11_09270	ENOG4108JPW	Aminotransferase
TthHC11_09280	ENOG4108YZ4	nudix hydrolase
TthHC11_09310	ENOG4105KHN	chorismate mutase
TthHC11_09340	ENOG4107Y3Y	amidohydrolase
TthHC11_09360	ENOG4105DTQ	mandelate racemase muconate lactonizing
TthHC11_09370	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
TthHC11_09390	ENOG4108UQV	Membrane
TthHC11_09400	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
TthHC11_09420	ENOG4105C6X	Major Facilitator
TthHC11_09430	ENOG4108SHN	Glycosyl transferase, family 2
TthHC11_09440	ENOG4107V8I	Glycosyl transferases group 1
TthHC11_09470	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
TthHC11_09510	ENOG4105C26	Dehydrogenase
TthHC11_09520	ENOG4108CCU	Ribonucleotide-diphosphate reductase subunit beta
TthHC11_09530	ENOG4105E2A	Dehydrogenase
TthHC11_09560	ENOG4105CEY	Amp-dependent synthetase and ligase
TthHC11_09590	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
TthHC11_09620	ENOG4105CHU	acetyl-coa acetyltransferase
TthHC11_09630	ENOG4105C1G	acyl-Coa dehydrogenase
TthHC11_09640	ENOG4105C8N	cysteinyl-tRNA synthetase
TthHC11_09650	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
TthHC11_09660	ENOG41068KF	Universal stress protein
TthHC11_09700	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
TthHC11_09720	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
TthHC11_09730	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
TthHC11_09740	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
TthHC11_09750	ENOG4107ZYJ	bioY protein
TthHC11_09760	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
TthHC11_09770	ENOG4105BZA	Phosphoglycerate kinase
TthHC11_09800	ENOG4105C8Y	Acetylornithine aminotransferase
TthHC11_09810	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
TthHC11_09830	ENOG41081CK	Memo-like protein
TthHC11_09840	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
TthHC11_09850	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
TthHC11_09870	ENOG4106H78	methyltransferase
TthHC11_09880	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
TthHC11_09890	ENOG4105DC1	bifunctional purine biosynthesis protein purh
TthHC11_09900	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
TthHC11_09930	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
TthHC11_10080	ENOG4105CP7	Triose-phosphate isomerase
TthHC11_10090	ENOG4105ECK	Fatty Acid Desaturase
TthHC11_10100	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
TthHC11_10110	ENOG4105EPR	degv family
TthHC11_10120	ENOG4105EPR	degv family
TthHC11_10160	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
TthHC11_10180	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
TthHC11_10200	ENOG4105C26	Dehydrogenase
TthHC11_10210	ENOG4105EFA	4-hydroxyphenylacetate
TthHC11_10220	ENOG4105MXW	flavin reductase domain protein, FMN-binding
TthHC11_10250	ENOG4105C32	Amino acid ABC transporter (Permease)
TthHC11_10260	ENOG4105C0Z	ABC transporter
TthHC11_10270	ENOG4108IV0	ABC, transporter
TthHC11_10280	ENOG4107YAU	phenylacetic acid degradation protein
TthHC11_10290	ENOG4105DZS	Phenylacetate-CoA ligase
TthHC11_10310	ENOG4105DXM	phenylacetic acid degradation protein
TthHC11_10350	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
TthHC11_10370	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TthHC11_10430	ENOG4107NFR	Fructose-1,6-bisphosphatase
TthHC11_10450	ENOG4108UQY	Iron-storage protein
TthHC11_10460	ENOG4108IYU	L-aspartate oxidase
TthHC11_10470	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
TthHC11_10480	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
TthHC11_10490	ENOG4105C7Z	Conserved Protein
TthHC11_10500	ENOG4105CHU	acetyl-coa acetyltransferase
TthHC11_10510	ENOG4105P4J	Allophanate hydrolase, subunit 1
TthHC11_10520	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
TthHC11_10560	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TthHC11_10590	ENOG4105ETX	regulatoR
TthHC11_10600	ENOG4105C26	Dehydrogenase
TthHC11_10620	ENOG4105C9X	ppx gppa phosphatase
TthHC11_10630	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
TthHC11_10640	ENOG4105C4R	Atp-dependent dna helicase
TthHC11_10680	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
TthHC11_10690	ENOG4106F60	Histidine kinase
TthHC11_10720	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
TthHC11_10750	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TthHC11_10760	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TthHC11_10840	ENOG4107U9H	DNA polymerase
TthHC11_10890	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
TthHC11_10900	ENOG4105KHC	sulfurtransferase
TthHC11_10910	ENOG4105EJQ	L-serine dehydratase
TthHC11_10920	ENOG4105WH1	Two component transcriptional regulator luxr family
TthHC11_10930	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
TthHC11_10940	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
TthHC11_10950	ENOG4106GF2	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
TthHC11_10960	ENOG4105VB6	UPF0109 protein
TthHC11_10970	ENOG4105K5M	30s ribosomal protein S16
TthHC11_10980	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TthHC11_11030	ENOG4105CRK	lysyL-tRNA synthetase
TthHC11_11040	ENOG4105RTX	GreA GreB family elongation factor
TthHC11_11060	ENOG41080IJ	Diacylglycerol kinase
TthHC11_11070	ENOG41080V7	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
TthHC11_11080	ENOG4105C9A	Phoh family
TthHC11_11100	ENOG4105DI5	UPF0365 protein
TthHC11_11120	ENOG4105E2X	shikimate dehydrogenase
TthHC11_11160	ENOG4105C2M	dna polymerase I
TthHC11_11170	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
TthHC11_11190	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
TthHC11_11200	ENOG41065RQ	ADP-ribosylation crystallin J1
TthHC11_11210	ENOG4105CJW	magnesium transporter
TthHC11_11230	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
TthHC11_11250	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
TthHC11_11260	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
TthHC11_11270	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
TthHC11_11280	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
TthHC11_11290	ENOG4105DC7	peptidase M24
TthHC11_11310	ENOG4105FRN	stage II sporulation protein
TthHC11_11330	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TthHC11_11340	ENOG41082DI	50s ribosomal protein l31
TthHC11_11360	ENOG4108V6E	Cell division protein mraZ
TthHC11_11370	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
TthHC11_11390	ENOG4105CJN	penicillin-binding protein
TthHC11_11400	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
TthHC11_11420	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
TthHC11_11430	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
TthHC11_11440	ENOG4105CNI	cell division protein FtsW
TthHC11_11450	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
TthHC11_11460	ENOG4105DFU	Cell wall formation (By similarity)
TthHC11_11470	ENOG4107QWW	Cell wall formation (By similarity)
TthHC11_11490	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
TthHC11_11510	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
TthHC11_11530	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
TthHC11_11550	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
TthHC11_11560	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
TthHC11_11570	ENOG4107R2U	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
TthHC11_11580	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
TthHC11_11590	ENOG4105DIH	basic membrane
TthHC11_11600	ENOG4108JQ9	ABC transporter
TthHC11_11700	ENOG4105CPK	Glycosyl transferase (Group 1
TthHC11_11710	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
TthHC11_11730	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
TthHC11_11740	ENOG4108SA1	esterase
TthHC11_11770	ENOG4105DF6	Fe-S oxidoreductase
TthHC11_11800	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
TthHC11_11810	ENOG41082MB	Involved in the transcription termination process (By similarity)
TthHC11_11830	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
TthHC11_11840	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
TthHC11_11850	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
TthHC11_11890	ENOG4105CYW	agmatinase
TthHC11_11920	ENOG4105CXV	gliding motility protein
TthHC11_11940	ENOG4105NAA	Cytochrome C oxidase, subunit II
TthHC11_11950	ENOG4107RQ2	Cytochrome c oxidase, subunit I
TthHC11_11970	ENOG4107RGD	Major Facilitator superfamily
TthHC11_11980	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
TthHC11_11990	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TthHC11_12000	ENOG4105CN5	Metallo-Beta-Lactamase
TthHC11_12020	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
TthHC11_12030	ENOG4105BZU	Histidine kinase
TthHC11_12040	ENOG4105C1G	acyl-Coa dehydrogenase
TthHC11_12050	ENOG4105BZJ	Electron transfer flavoprotein
TthHC11_12060	ENOG4105C10	Electron transfer flavoprotein
TthHC11_12080	ENOG4108HNZ	carboxyl transferase
TthHC11_12090	ENOG4105E50	uracil-dna glycosylase
TthHC11_12100	ENOG4105DCG	PHP domain protein
TthHC11_12130	ENOG4105C88	aminopeptidase
TthHC11_12170	ENOG4108FXY	Cys/Met metabolism PLP-dependent enzyme
TthHC11_12200	ENOG4105CDA	abc transporter atp-binding protein
TthHC11_12220	ENOG4105D78	K07001 NTE family protein
TthHC11_12230	ENOG4105VT3	DNA binding domain protein, excisionase family
TthHC11_12250	ENOG4105DK0	Indole-3-glycerol phosphate synthase
TthHC11_12260	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
TthHC11_12280	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
TthHC11_12300	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
TthHC11_12310	ENOG4105E5Q	amino acid AbC transporter
TthHC11_12320	ENOG4105EAB	amino acid AbC transporter
TthHC11_12340	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
TthHC11_12350	ENOG4105C1A	potassium transporter peripheral membrane
TthHC11_12360	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
TthHC11_12370	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
TthHC11_12380	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
TthHC11_12410	ENOG4105KJF	protein tyrosine phosphatase
TthHC11_12430	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
TthHC11_12470	ENOG4105C3G	gtp-binding protein
TthHC11_12480	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
TthHC11_12500	ENOG4108Z03	MAF-like protein
TthHC11_12530	ENOG4105CJN	penicillin-binding protein
TthHC11_12540	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
TthHC11_12550	ENOG4108SJC	Membrane
TthHC11_12590	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
TthHC11_12600	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
TthHC11_12620	ENOG4105DBV	ornithine carbamoyltransferase
TthHC11_12650	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
TthHC11_12670	ENOG4105CJ1	ABC, transporter
TthHC11_12710	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
TthHC11_12730	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
TthHC11_12740	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
TthHC11_12760	ENOG4105C7K	acetolactate synthase
TthHC11_12770	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
TthHC11_12830	ENOG4108VAU	general secretion pathway protein G
TthHC11_12900	ENOG4105C31	Tryptophanyl-tRNA synthetase
TthHC11_12930	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TthHC11_12940	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TthHC11_12950	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
TthHC11_12990	ENOG4105C01	Dihydroxy-acid dehydratase
TthHC11_13010	ENOG4107RUE	extracellular solute-binding protein family 1
TthHC11_13020	ENOG4105D38	putrescine abc transporter
TthHC11_13030	ENOG4105F38	ABC transporter, permease
TthHC11_13040	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TthHC11_13050	ENOG4105CNI	cell division protein FtsW
TthHC11_13060	ENOG4108CHF	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
TthHC11_13070	ENOG4107QMS	site-determining protein
TthHC11_13120	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TthHC11_13130	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TthHC11_13140	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TthHC11_13150	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
TthHC11_13160	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TthHC11_13200	ENOG4105K8R	UPF0145 protein
TthHC11_13210	ENOG4108I5C	dEAD DEAH box helicase
TthHC11_13240	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
TthHC11_13250	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
TthHC11_13260	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
TthHC11_13270	ENOG4105C1V	Peptidase, M16
TthHC11_13320	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TthHC11_13330	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
TthHC11_13340	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
TthHC11_13350	ENOG410704R	Produces ATP from ADP in the presence of a proton gradient across the membrane
TthHC11_13360	ENOG41089ID	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TthHC11_13370	ENOG4106287	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TthHC11_13390	ENOG4105EBX	v-type atpase
TthHC11_13440	ENOG4105E8R	UPF0173 metal-dependent hydrolase
TthHC11_13450	ENOG4108V5V	Serine Threonine protein kinase
TthHC11_13460	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TthHC11_13470	ENOG4105CJR	Integral membrane protein (MviN
TthHC11_13490	ENOG4105EYH	Exonuclease
TthHC11_13540	ENOG4105MS2	ribosomal subunit Interface protein
TthHC11_13550	ENOG4105CAK	Cell division ATP-binding protein ftsE
TthHC11_13560	ENOG4105CN1	protease
TthHC11_13580	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
TthHC11_13590	ENOG4105E66	phosphoriboisomerase A
TthHC11_13600	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TthHC11_13630	ENOG4105UIB	(ABC) transporter
TthHC11_13640	ENOG4105C2J	ABC transporter
TthHC11_13650	ENOG41080QG	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
TthHC11_13670	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TthHC11_13710	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
TthHC11_13720	ENOG4105ESV	Glycosyl transferase, family 4
TthHC11_13730	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
TthHC11_13810	ENOG4105C0H	protease
TthHC11_13820	ENOG4105CIY	formyltetrahydrofolate deformylase
TthHC11_13830	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
TthHC11_13840	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
TthHC11_13850	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
TthHC11_13870	ENOG41067HZ	cytochrome C, class I
TthHC11_13890	ENOG4105CGH	5'-nucleotidase
TthHC11_13900	ENOG4105C5F	glutamine synthetase
TthHC11_13920	ENOG4105C32	Amino acid ABC transporter (Permease)
TthHC11_13930	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
TthHC11_13940	ENOG4105C0Z	ABC transporter
TthHC11_13950	ENOG4108IV0	ABC, transporter
TthHC11_13960	ENOG4105DEF	Extracellular solute-binding protein, family 5
TthHC11_13970	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
TthHC11_13980	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TthHC11_14000	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
TthHC11_14010	ENOG4105BZ1	(ABC) transporter
TthHC11_14020	ENOG4105BZ1	(ABC) transporter
TthHC11_14030	ENOG4105BZN	citrate synthase
TthHC11_14040	ENOG4105D06	uba thif-type nad fad binding protein
TthHC11_14050	ENOG4105DG6	mannose-6-phosphate isomerase
TthHC11_14070	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
TthHC11_14090	ENOG4105K70	DNA-binding protein
TthHC11_14120	ENOG4105WH1	Two component transcriptional regulator luxr family
TthHC11_14130	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TthHC11_14140	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
TthHC11_14150	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TthHC11_14160	ENOG4105VF7	tolerance protein
TthHC11_14190	ENOG4108W63	CRP FNR family transcriptional regulator
TthHC11_14230	ENOG4105BZU	Histidine kinase
TthHC11_14270	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
TthHC11_14280	ENOG4107QR9	Iron-sulfur cluster binding protein
TthHC11_14290	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
TthHC11_14300	ENOG4105C3F	Signal peptidase i
TthHC11_14310	ENOG4105D78	K07001 NTE family protein
TthHC11_14320	ENOG4105D9P	serine threonine protein kinase
TthHC11_14340	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
TthHC11_14360	ENOG4107QNB	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
TthHC11_14380	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TthHC11_14400	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
TthHC11_14460	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
TthHC11_14470	ENOG4107ZC0	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
TthHC11_14480	ENOG4105D49	3-dehydroquinate synthase
TthHC11_14490	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TthHC11_14500	ENOG41084ZW	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
TthHC11_14530	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TthHC11_14540	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
TthHC11_14550	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
TthHC11_14560	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
TthHC11_14580	ENOG4108AH5	Binds directly to 16S ribosomal RNA (By similarity)
TthHC11_14600	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
TthHC11_14630	ENOG4105KWW	Biogenesis protein
TthHC11_14640	ENOG4107QX9	Thiol disulfide interChange protein
TthHC11_14650	ENOG4105DA4	cytochrome c-type biogenesis protein
TthHC11_14660	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
TthHC11_14670	ENOG41060IM	Heme exporter protein
TthHC11_14680	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
TthHC11_14690	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
TthHC11_14700	ENOG4107QIV	Cytochrome c biogenesis protein
TthHC11_14710	ENOG4105NQN	cytochrome C
TthHC11_14730	ENOG4107S7U	Sulfide dehydrogenase
TthHC11_14760	ENOG4105QN4	diheme cytochrome
TthHC11_14770	ENOG4108XRS	Monoheme cytochrome SoxX (Sulfur oxidation)
TthHC11_14780	ENOG4105CGH	5'-nucleotidase
TthHC11_14790	ENOG4108XRS	Monoheme cytochrome SoxX (Sulfur oxidation)
TthHC11_14800	ENOG4105QN4	diheme cytochrome
TthHC11_14840	ENOG41067HZ	cytochrome C, class I
TthHC11_14850	ENOG4108UCS	ABC, transporter
TthHC11_14890	ENOG4107QKV	phosphomannomutase
TthHC11_14910	ENOG4105CEY	Amp-dependent synthetase and ligase
TthHC11_14920	ENOG4105WKW	Pfam:DUF1458
TthHC11_14950	ENOG4105E39	Enoyl-CoA hydratase
TthHC11_14960	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
TthHC11_14970	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TthHC11_14980	ENOG4105IJJ	transcriptional regulator, crp fnr family
TthHC11_14990	ENOG4108N5B	2-phosphosulfolactate phosphatase
TthHC11_15000	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TthHC11_15010	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
TthHC11_15030	ENOG4108JIF	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
TthHC11_15050	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
TthHC11_15060	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
TthHC11_15070	ENOG4105CBT	Fructose-1,6-bisphosphatase
TthHC11_15080	ENOG4105DCF	alanine dehydrogenase
TthHC11_15090	ENOG4105CYC	Transferase
TthHC11_15100	ENOG4105F8V	Hydrolase, tatD family
TthHC11_15110	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
TthHC11_15130	ENOG4105C5S	asparaginyl-tRNA synthetase
TthHC11_15140	ENOG4105E33	succinate dehydrogenase
TthHC11_15180	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
TthHC11_15200	ENOG4105CIG	ABC transporter
TthHC11_15240	ENOG4105CEY	Amp-dependent synthetase and ligase
TthHC11_15250	ENOG4108UJD	30S ribosomal protein S9
TthHC11_15260	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
TthHC11_15270	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
TthHC11_15290	ENOG4105CBC	glutamate synthase
TthHC11_15310	ENOG4106YBV	Methyl-accepting chemotaxis
TthHC11_15320	ENOG4105CDU	Replicative dna helicase
TthHC11_15330	ENOG4105E4C	Lytic transglycosylase catalytic
TthHC11_15350	ENOG4105CJW	magnesium transporter
TthHC11_15380	ENOG4107S91	Sodium hydrogen exchanger
TthHC11_15390	ENOG4105NCW	Trka-c domain protein
TthHC11_15410	ENOG4108ZVP	Domain of unknown function (DUF1931)
TthHC11_15430	ENOG4105K63	Thioredoxin
TthHC11_15490	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TthHC11_15500	ENOG4108FYC	transcriptional regulator MERR family
TthHC11_15510	ENOG4105DVC	DnaJ domain protein
TthHC11_15520	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TthHC11_15530	ENOG4105CFG	Acts as a chaperone (By similarity)
TthHC11_15540	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TthHC11_15550	ENOG4105DR4	Methyltransferase
TthHC11_15560	ENOG4105D07	Signal peptide peptidase, SppA
TthHC11_15590	ENOG4108UKM	mov34 mpn pad-1 family protein
TthHC11_15600	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TthHC11_15610	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TthHC11_15620	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
TthHC11_15630	ENOG4108UT2	hemolysin iii
TthHC11_15650	ENOG41062D9	Histidine kinase
TthHC11_15680	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
TthHC11_15700	ENOG4108Z8I	decarboxylase
TthHC11_15750	ENOG4105C83	adenylosuccinate lyase
TthHC11_15770	ENOG4105C8V	SAICAR synthetase
TthHC11_15790	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
TthHC11_15810	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
TthHC11_15820	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
TthHC11_15830	ENOG4108T9W	RNA methylase
TthHC11_15860	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
TthHC11_15870	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
TthHC11_15880	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
TthHC11_15890	ENOG4105CIS	alcohol dehydrogenase
TthHC11_15930	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
TthHC11_15980	ENOG4108HMX	isocitrate dehydrogenase (NADP)
TthHC11_15990	ENOG4107VFR	oxidoreductase
TthHC11_16000	ENOG4108FWV	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
TthHC11_16020	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
TthHC11_16040	ENOG4105KA0	thioesterase Superfamily protein
TthHC11_16060	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
TthHC11_16070	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TthHC11_16080	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
TthHC11_16090	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
TthHC11_16100	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TthHC11_16120	ENOG41067KJ	GYD family
TthHC11_16130	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
TthHC11_16140	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TthHC11_16150	ENOG4107QX3	carboxylase
TthHC11_16160	ENOG41081FY	multiple antibiotic resistance (MarC)-related
TthHC11_16170	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
TthHC11_16180	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
TthHC11_16190	ENOG41079SJ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
TthHC11_16200	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
TthHC11_16220	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
TthHC11_16230	ENOG4105JFG	SpoIID LytB domain protein
TthHC11_16240	ENOG41074B2	UPF0747 protein
TthHC11_16260	ENOG4105E63	Pfam:DUF178
TthHC11_16340	ENOG4105D82	Glutamate dehydrogenase
TthHC11_16350	ENOG4105D82	Glutamate dehydrogenase
TthHC11_16360	ENOG4105C26	Dehydrogenase
TthHC11_16370	ENOG41062BK	proline dehydrogenase
TthHC11_16400	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
TthHC11_16410	ENOG4105XEZ	This methylase recognizes the double-stranded sequence TCGA, causes specific methylation on A-4 on both strands and protects the DNA from cleavage by the
TthHC11_16420	ENOG4106ZDB	Type II restriction enzyme
TthHC11_16440	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TthHC11_16450	ENOG4105CPF	Cell wall formation (By similarity)
TthHC11_16460	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
TthHC11_16470	ENOG4107UH2	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
TthHC11_16500	ENOG4105BZU	Histidine kinase
TthHC11_16510	ENOG4105ETX	regulatoR
TthHC11_16520	ENOG4105D9P	serine threonine protein kinase
TthHC11_16530	ENOG4108ZF3	Phosphatase
TthHC11_16560	ENOG4105D52	delta-aminolevulinic acid dehydratase
TthHC11_16570	ENOG41080DW	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
TthHC11_16580	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
TthHC11_16630	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
TthHC11_16640	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
TthHC11_16650	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
TthHC11_16690	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
TthHC11_16700	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
TthHC11_16750	ENOG4107YU2	histidine triad (hIT) protein
TthHC11_16760	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TthHC11_16770	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
TthHC11_16780	ENOG4105C87	Aminotransferase class I and II
TthHC11_16790	ENOG4105VN1	Heat shock protein
TthHC11_16800	ENOG4105KHC	sulfurtransferase
TthHC11_16810	ENOG4105C5X	domain protein
TthHC11_16830	ENOG4108Z9K	Osmotically inducible protein
TthHC11_16860	ENOG4107QKW	extracellular solute-binding protein family 1
TthHC11_16880	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TthHC11_16890	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
TthHC11_16900	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
TthHC11_16920	ENOG4107RNA	Nickel ABC transporter, periplasmic nickel-binding protein
TthHC11_16960	ENOG4105DC7	peptidase M24
TthHC11_16970	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TthHC11_17000	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
TthHC11_17010	ENOG4106TD9	Diguanylate cyclase
TthHC11_17030	ENOG4105BZU	Histidine kinase
TthHC11_17040	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
TthHC11_17050	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
TthHC11_17060	ENOG4108URH	decarboxylase
TthHC11_17070	ENOG4105C98	muts2 protein
TthHC11_17090	ENOG4107R28	alpha amylase, catalytic region
TthHC11_17110	ENOG4105EG2	ABC transporter, permease
TthHC11_17120	ENOG4105D56	permease protein
TthHC11_17150	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
TthHC11_17160	ENOG4105EAH	synthase
TthHC11_17240	ENOG4108ZT0	50S ribosomal protein l17
TthHC11_17250	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TthHC11_17260	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
TthHC11_17270	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
TthHC11_17280	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TthHC11_17290	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
TthHC11_17310	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
TthHC11_17320	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
TthHC11_17330	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TthHC11_17340	ENOG410856V	50S ribosomal protein L30
TthHC11_17350	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
TthHC11_17360	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
TthHC11_17370	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
TthHC11_17380	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
TthHC11_17390	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
TthHC11_17400	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TthHC11_17410	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
TthHC11_17420	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
TthHC11_17430	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
TthHC11_17440	ENOG4108CHD	50s ribosomal protein l29
TthHC11_17450	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
TthHC11_17460	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
TthHC11_17470	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
TthHC11_17480	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
TthHC11_17490	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TthHC11_17500	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
TthHC11_17510	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
TthHC11_17520	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
TthHC11_17530	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
TthHC11_17540	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TthHC11_17550	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TthHC11_17560	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
TthHC11_17570	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
TthHC11_17670	ENOG4105PW4	Sugar fermentation stimulation protein homolog
TthHC11_17730	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
TthHC11_17740	ENOG4107T9V	chlorite dismutase
TthHC11_17750	ENOG4105D8X	mechanosensitive ion channel
TthHC11_17770	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
TthHC11_17780	ENOG4105C59	p-type ATPase
TthHC11_17820	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TthHC11_17830	ENOG4105EB3	Histidine kinase
TthHC11_17870	ENOG4107QX9	Thiol disulfide interChange protein
TthHC11_17880	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TthHC11_17920	ENOG4107STQ	Multicopper oxidase
TthHC11_17940	ENOG4105C9B	Cysteine desulfurase
TthHC11_17950	ENOG4108UNV	SUF system FeS assembly protein, NifU family
TthHC11_17970	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
TthHC11_17990	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
TthHC11_18010	ENOG4107QV3	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
TthHC11_18020	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
TthHC11_18040	ENOG4107YEI	lmbE family
TthHC11_18060	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
TthHC11_18070	ENOG4105K63	Thioredoxin
TthHC11_18080	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TthHC11_18090	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TthHC11_18110	ENOG4105CPK	Glycosyl transferase (Group 1
TthHC11_18150	ENOG4105C8Y	Acetylornithine aminotransferase
TthHC11_18180	ENOG4108KB0	deacetylase
TthHC11_18200	ENOG4105BZU	Histidine kinase
TthHC11_18260	ENOG4107SFQ	iron-sulfur binding
TthHC11_18290	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
TthHC11_18300	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
TthHC11_18360	ENOG4105CZX	twitching motility protein
TthHC11_18370	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
TthHC11_18420	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
TthHC11_18430	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TthHC11_18440	ENOG4105K46	50S ribosomal protein l27
TthHC11_18450	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
TthHC11_18530	ENOG4105D5G	Transposase
TthHC11_18580	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TthHC11_18600	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
TthHC11_18630	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
TthHC11_18640	ENOG4108Z5K	methylglyoxal synthase
TthHC11_18660	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
TthHC11_18670	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
TthHC11_18680	ENOG4105F4P	)-transporter
TthHC11_18710	ENOG41090A4	Pterin carbinolamine dehydratase
TthHC11_18740	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
TthHC11_18750	ENOG4105E0C	molybdate abc transporter
TthHC11_18760	ENOG4105C4Y	ABC transporter
TthHC11_18790	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
TthHC11_18800	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TthHC11_18810	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TthHC11_18830	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
TthHC11_18840	ENOG4105DFF	Rod shape-determining protein mreb
TthHC11_18850	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
TthHC11_18860	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
TthHC11_18870	ENOG4108784	2'-5' rna ligase
TthHC11_18880	ENOG4105CEV	competence damage-inducible protein
TthHC11_18890	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
TthHC11_18920	ENOG4105DTQ	mandelate racemase muconate lactonizing
TthHC11_18950	ENOG4105E4X	binding-protein-dependent transport systems inner membrane Component
TthHC11_18970	ENOG4106B0N	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
TthHC11_18990	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TthHC11_19010	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TthHC11_19020	ENOG4108I0Y	(ABC) transporter
TthHC11_19030	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
TthHC11_19060	ENOG4105C3K	feS assembly ATPase SufC
TthHC11_19070	ENOG4105DIW	FeS assembly protein SUFB
TthHC11_19090	ENOG4105VQD	rieske 2fe-2S domain-containing protein
TthHC11_19100	ENOG4107QYG	anthranilate phosphoribosyltransferase
TthHC11_19110	ENOG4105DDQ	anthranilate synthase
TthHC11_19120	ENOG4105CRQ	synthase (Component I)
TthHC11_19200	ENOG4108UXE	Protein tyrosine phosphatase
TthHC11_19210	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TthHC11_19220	ENOG4105UIB	(ABC) transporter
TthHC11_19260	ENOG4105MA4	psp1 domain protein
TthHC11_19270	ENOG4107QRG	dna polymerase iii
TthHC11_19340	ENOG4105C22	threonyL-tRNA synthetase
TthHC11_19350	ENOG4105EUJ	GTP cyclohydrolase i
TthHC11_19360	ENOG4108Z0R	Transferase
TthHC11_19370	ENOG41062IR	nudix hydrolase
TthHC11_19390	ENOG4105CI3	gtp-binding protein typa
TthHC11_19410	ENOG4105D1H	recombination factor protein RarA
TthHC11_19430	ENOG4105DRS	transport system, permease
TthHC11_19440	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
TthHC11_19450	ENOG4105CJ1	ABC, transporter
TthHC11_19480	ENOG4105C7S	Dehydrogenase
TthHC11_19490	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
TthHC11_19510	ENOG4105ZU5	s-layer protein
TthHC11_19520	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TthHC11_19530	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
TthHC11_19570	ENOG4105C4K	Nad synthetase
TthHC11_19590	ENOG4107RFW	hydrolase family 57
TthHC11_19600	ENOG4107U4Q	acetylglutamate kinase
TthHC11_19610	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
TthHC11_19640	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
TthHC11_19650	ENOG4106928	lysine biosynthesis protein LysW
TthHC11_19670	ENOG4108S93	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TthHC11_19680	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TthHC11_19710	ENOG4108JZA	Homocitrate synthase
TthHC11_19720	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
TthHC11_19730	ENOG4105C1G	acyl-Coa dehydrogenase
TthHC11_19740	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
TthHC11_19760	ENOG4105C3M	thioredoxin reductase
TthHC11_19800	ENOG4108IUW	ABC transporter
TthHC11_19820	ENOG4108WBT	adenosyltransferase
TthHC11_19850	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
TthHC11_19860	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
TthHC11_19890	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
TthHC11_19900	ENOG4107EUI	c reductase, iron-sulfur
TthHC11_19920	ENOG41067HZ	cytochrome C, class I
TthHC11_19960	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
TthHC11_19970	ENOG4105C1G	acyl-Coa dehydrogenase
TthHC11_19990	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
TthHC11_20030	ENOG41082VC	UPF0145 protein
TthHC11_20050	ENOG4105DXN	mazG family
TthHC11_20070	ENOG4107R7Y	intracellular protease Pfpi family
TthHC11_20080	ENOG4107RRU	Involved in both the arginine and lysine biosynthetic pathways (By similarity)
TthHC11_20100	ENOG4105C6E	dna polymerase iii
TthHC11_20110	ENOG4105VPX	protein, conserved in bacteria
TthHC11_20130	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
TthHC11_20140	ENOG4105DQU	oxidoreductase, subunit beta
TthHC11_20150	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
TthHC11_20160	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
TthHC11_20170	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
TthHC11_20190	ENOG4105CTQ	phosphohexokinase
TthHC11_20220	ENOG4105F0N	pyrophosphate phospho-hydrolase
TthHC11_20250	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
TthHC11_20260	ENOG4105FA0	parb-like partition protein
TthHC11_20270	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
TthHC11_20280	ENOG4107YBR	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
TthHC11_20290	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
TthHC11_20400	ENOG4108IV0	ABC, transporter
TthHC11_20410	ENOG4105C0Z	ABC transporter
TthHC11_20420	ENOG4105CEY	Amp-dependent synthetase and ligase
TthHC11_20440	ENOG4105C32	Amino acid ABC transporter (Permease)
TthHC11_20470	ENOG4105C1G	acyl-Coa dehydrogenase
TthHC11_20490	ENOG4105CHR	reductase
TthHC11_20500	ENOG4105DXM	phenylacetic acid degradation protein
TthHC11_20520	ENOG4105CEY	Amp-dependent synthetase and ligase
TthHC11_20570	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TthHC11_20820	ENOG41066GP	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
TthHC11_20930	ENOG4106EQQ	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity)
TthHC11_20950	ENOG4107R4I	Periplasmic binding protein
TthHC11_20960	ENOG4105EHG	Permease protein
TthHC11_20970	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
TthHC11_20990	ENOG4108MES	Periplasmic binding protein
TthHC11_21020	ENOG4105BZU	Histidine kinase
TthHC11_21070	ENOG4105CPI	Metal Dependent Phosphohydrolase
TthHC11_21090	ENOG4105RSG	Anti-sigma-K factor RskA
TthHC11_21120	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TthHC11_21140	ENOG4105NAU	thioesterase Superfamily protein
TthHC11_21200	ENOG4108R4U	Hnh endonuclease
TthHC11_21220	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TthHC11_21280	ENOG4106EQQ	Allows bacterial pathogens to use the host heme as an iron source. Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring to the oxo-bilirubin chromophore staphylobilin (a mixture of the linear tetrapyrroles 5-oxo-delta- bilirubin and 15-oxo-beta-bilirubin) in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron (By similarity)
TthHC11_21390	ENOG4107QKC	Oxidoreductase alpha (molybdopterin) subunit
TthHC11_21400	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
TthHC11_21410	ENOG4105E7W	lamb ycsf family protein
TthHC11_21450	ENOG4105FB9	CRISPR-associated protein
TthHC11_21500	ENOG4105C9U	ATP-dependent DNA helicase RecQ
TthHC11_21540	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
TthHC11_21560	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
TthHC11_21720	ENOG4105DQ6	Transposase
TthHC11_21740	ENOG4105DR5	peptidase
TthHC11_21790	ENOG4105CNT	hydrolase family 2
TthHC11_21890	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
TthHC11_21900	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
TthHC11_21920	ENOG4107XPA	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
TthHC11_21950	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TthHC11_21960	ENOG4105D9G	High-affinity
TthHC11_21970	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
TthHC11_21980	ENOG41081F0	Precorrin-8x methylmutase
TthHC11_21990	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
TthHC11_22000	ENOG4105DVK	Precorrin-2 c20-methyltransferase
TthHC11_22010	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
TthHC11_22020	ENOG4105E4R	Precorrin-3B C17-methyltransferase
TthHC11_22030	ENOG4108P62	biosynthesis protein (CbiG)
TthHC11_22040	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
TthHC11_22060	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
TthHC11_22070	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
TthHC11_22080	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
TthHC11_22110	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TthHC11_22130	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
TthHC11_22140	ENOG4105G6Z	alkaline phosphatase
TthHC11_22190	ENOG4108UHU	Aldolase
TthHC11_22200	ENOG4107HP6	Transcriptional regulator
TthHC11_22210	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
TthHC11_22230	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
TthHC11_22240	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
TthHC11_22270	ENOG4105CHR	reductase
TthHC11_22300	ENOG4105HS6	binding-protein-dependent transport systems inner membrane Component
TthHC11_22330	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
TthHC11_22370	ENOG4105EWK	phytoene
TthHC11_22380	ENOG4105CGD	Nad-dependent epimerase dehydratase
TthHC11_22460	ENOG4105FE1	phytoene synthase
TthHC11_22540	ENOG4105EWK	phytoene
TthHC11_22550	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
TthHC11_22590	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
TthHC11_22600	ENOG4107R49	K07407 alpha-galactosidase EC 3.2.1.22
TthHC11_22670	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TthHC11_22700	ENOG4105FA0	parb-like partition protein
TthHC11_22710	ENOG41089N3	Inherit from COG: cobyrinic Acid a,c-diamide synthase
TthHC11_22800	ENOG4107V8H	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
TthHC11_22910	ENOG4105C2C	drug resistance transporter, Bcr CflA
TthHC11_22930	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
TthHC11_22950	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
TthHC11_t00350	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation