locus-tag	class	description
JCM10941_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
JCM10941_00020	COG0592	DNA-directed DNA polymerase activity
JCM10941_00030	COG0148	phosphopyruvate hydratase activity
JCM10941_00040	COG0469	pyruvate kinase activity
JCM10941_00060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JCM10941_00070	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
JCM10941_00090	COG1842	Phage shock protein A
JCM10941_00100	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
JCM10941_00120	COG0142	geranyltranstransferase activity
JCM10941_00150	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
JCM10941_00160	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
JCM10941_00180	COG0297	glycogen (starch) synthase activity
JCM10941_00190	COG2105	PFAM AIG2 family protein
JCM10941_00200	COG0745	RESPONSE REGULATOR receiver
JCM10941_00220	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
JCM10941_00230	COG1067	ATP-dependent peptidase activity
JCM10941_00270	COG0667	Aldo Keto reductase
JCM10941_00330	COG2002	toxin-antitoxin pair type II binding
JCM10941_00410	COG0277	FAD linked oxidase domain protein
JCM10941_00430	COG0227	Belongs to the bacterial ribosomal protein bL28 family
JCM10941_00450	COG0475	glutathione-regulated potassium exporter activity
JCM10941_00450	COG0569	domain protein
JCM10941_00470	COG0436	Aminotransferase
JCM10941_00500	COG1597	lipid kinase activity
JCM10941_00530	COG0123	including yeast histone deacetylase and acetoin utilization protein
JCM10941_00550	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
JCM10941_00570	COG0004	ammonium transporteR
JCM10941_00580	COG0347	Belongs to the P(II) protein family
JCM10941_00590	COG1420	regulation of RNA biosynthetic process
JCM10941_00600	COG0314	molybdopterin synthase activity
JCM10941_00630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
JCM10941_00640	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
JCM10941_00660	COG0277	FAD linked oxidase domain protein
JCM10941_00720	COG1126	abc transporter atp-binding protein
JCM10941_00730	COG2720	vancomycin resistance protein
JCM10941_00750	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
JCM10941_00760	COG1372	Participates in initiation and elongation during chromosome replication
JCM10941_00760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JCM10941_00770	COG0135	phosphoribosylanthranilate isomerase activity
JCM10941_00800	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JCM10941_00820	COG4712	double-strand break repair protein
JCM10941_00840	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
JCM10941_00850	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JCM10941_00860	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JCM10941_00870	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JCM10941_00880	COG0649	NAD binding
JCM10941_00890	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
JCM10941_00900	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
JCM10941_00910	COG1034	ATP synthesis coupled electron transport
JCM10941_00920	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
JCM10941_00930	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JCM10941_00940	COG0839	Belongs to the complex I subunit 6 family
JCM10941_00950	COG0713	ATP synthesis coupled electron transport
JCM10941_00960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
JCM10941_00970	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
JCM10941_00980	COG1007	ATP synthesis coupled electron transport
JCM10941_00990	COG0018	arginyl-trna synthetase
JCM10941_01000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JCM10941_01010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
JCM10941_01040	COG2070	2-Nitropropane dioxygenase
JCM10941_01070	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
JCM10941_01100	COG0513	Belongs to the DEAD box helicase family
JCM10941_01110	COG0303	'Molybdopterin
JCM10941_01150	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
JCM10941_01160	COG0442	prolyl-tRNA aminoacylation
JCM10941_01170	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
JCM10941_01190	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JCM10941_01210	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
JCM10941_01220	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JCM10941_01220	COG0758	DNA mediated transformation
JCM10941_01230	COG3546	catalase activity
JCM10941_01240	COG0583	DNA-binding transcription factor activity
JCM10941_01280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JCM10941_01290	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
JCM10941_01300	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
JCM10941_01310	COG0717	Belongs to the dCTP deaminase family
JCM10941_01340	COG0300	oxidoreductase activity
JCM10941_01350	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
JCM10941_01390	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
JCM10941_01390	COG0515	serine threonine protein kinase
JCM10941_01410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
JCM10941_01430	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
JCM10941_01440	COG0704	Plays a role in the regulation of phosphate uptake
JCM10941_01450	COG4191	Histidine kinase
JCM10941_01460	COG0745	RESPONSE REGULATOR receiver
JCM10941_01470	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JCM10941_01490	COG1187	pseudouridine synthase activity
JCM10941_01530	COG2414	aldehyde ferredoxin oxidoreductase
JCM10941_01580	COG1902	pentaerythritol trinitrate reductase activity
JCM10941_01620	COG0495	leucyl-tRNA aminoacylation
JCM10941_01630	COG0539	negative regulation of cytoplasmic translation
JCM10941_01640	COG0802	atpase or kinase
JCM10941_01670	COG4242	Belongs to the peptidase S51 family
JCM10941_01680	COG1309	transcriptional regulator
JCM10941_01710	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
JCM10941_01720	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
JCM10941_01730	COG1968	undecaprenyl-diphosphatase activity
JCM10941_01740	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
JCM10941_01750	COG0484	heat shock protein binding
JCM10941_01760	COG1278	Cold shock
JCM10941_01780	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JCM10941_01850	COG0508	dehydrogenase complex catalyzes the overall conversion of
JCM10941_01870	COG0583	DNA-binding transcription factor activity
JCM10941_01880	COG0631	protein serine/threonine phosphatase activity
JCM10941_01890	COG0105	UTP biosynthetic process
JCM10941_01910	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
JCM10941_01940	COG0477	Major facilitator Superfamily
JCM10941_01970	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JCM10941_01990	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
JCM10941_02000	COG2272	Belongs to the type-B carboxylesterase lipase family
JCM10941_02010	COG0243	molybdopterin cofactor binding
JCM10941_02030	COG3177	Filamentation induced by cAMP protein fic
JCM10941_02050	COG0697	spore germination
JCM10941_02080	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
JCM10941_02100	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
JCM10941_02110	COG0222	ribosome binding
JCM10941_02120	COG4591	ABC-type transport system involved in lipoprotein release permease component
JCM10941_02130	COG3583	domain protein
JCM10941_02130	COG3584	3D domain protein
JCM10941_02150	COG1461	Dihydroxyacetone kinase
JCM10941_02170	COG0686	Belongs to the AlaDH PNT family
JCM10941_02180	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
JCM10941_02200	COG1187	pseudouridine synthase activity
JCM10941_02210	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
JCM10941_02230	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
JCM10941_02240	COG2226	methyltransferase
JCM10941_02290	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
JCM10941_02300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
JCM10941_02310	COG0022	dehydrogenase e1 component
JCM10941_02320	COG1598	PFAM Uncharacterised protein family UPF0150
JCM10941_02350	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
JCM10941_02420	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
JCM10941_02430	COG0321	lipoyl(octanoyl) transferase activity
JCM10941_02440	COG0300	oxidoreductase activity
JCM10941_02450	COG0359	binds to the 23S rRNA
JCM10941_02460	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
JCM10941_02470	COG0629	single-stranded DNA binding
JCM10941_02490	COG0081	regulation of translation
JCM10941_02510	COG0250	Participates in transcription elongation, termination and antitermination
JCM10941_02520	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
JCM10941_02530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
JCM10941_02540	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
JCM10941_02550	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
JCM10941_02580	COG0735	belongs to the Fur family
JCM10941_02590	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
JCM10941_02610	COG0482	sulfurtransferase activity
JCM10941_02620	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
JCM10941_02630	COG0573	inorganic phosphate transmembrane transporter activity
JCM10941_02640	COG0581	inorganic phosphate transmembrane transporter activity
JCM10941_02650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
JCM10941_02670	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
JCM10941_02690	COG1388	LysM domain
JCM10941_02690	COG0791	NLP P60 protein
JCM10941_02700	COG0778	Nitroreductase
JCM10941_02720	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
JCM10941_02730	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
JCM10941_02740	COG0459	protein refolding
JCM10941_02750	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
JCM10941_02780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JCM10941_02800	COG0166	Belongs to the GPI family
JCM10941_02810	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
JCM10941_02830	COG0505	Belongs to the CarA family
JCM10941_02860	COG0165	Argininosuccinate lyase
JCM10941_02870	COG0137	argininosuccinate synthase activity
JCM10941_02900	COG1404	Belongs to the peptidase S8 family
JCM10941_02920	COG0508	dehydrogenase complex catalyzes the overall conversion of
JCM10941_02940	COG1024	Enoyl-CoA hydratase
JCM10941_02950	COG0632	four-way junction helicase activity
JCM10941_02960	COG1011	Hydrolase
JCM10941_02980	COG1611	Belongs to the LOG family
JCM10941_03000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
JCM10941_03010	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JCM10941_03030	COG1940	carbohydrate kinase activity
JCM10941_03080	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
JCM10941_03090	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
JCM10941_03100	COG0343	queuine tRNA-ribosyltransferase activity
JCM10941_03140	COG0109	protoheme IX farnesyltransferase activity
JCM10941_03140	COG1612	heme a metabolic process
JCM10941_03150	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JCM10941_03150	COG2010	Cytochrome c
JCM10941_03160	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JCM10941_03160	COG1845	cytochrome c oxidase, subunit III
JCM10941_03220	COG0391	Required for morphogenesis under gluconeogenic growth conditions
JCM10941_03230	COG1660	Displays ATPase and GTPase activities
JCM10941_03240	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
JCM10941_03270	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
JCM10941_03280	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
JCM10941_03310	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
JCM10941_03320	COG1335	isochorismatase
JCM10941_03330	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
JCM10941_03350	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JCM10941_03370	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
JCM10941_03380	COG1993	acr, cog1993
JCM10941_03390	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
JCM10941_03400	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
JCM10941_03450	COG0521	Mo-molybdopterin cofactor biosynthetic process
JCM10941_03460	COG0436	Aminotransferase
JCM10941_03470	COG0285	dihydrofolate synthase activity
JCM10941_03490	COG0181	hydroxymethylbilane synthase activity
JCM10941_03510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
JCM10941_03520	COG1950	PFAM Membrane protein of
JCM10941_03530	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
JCM10941_03530	COG0517	IMP dehydrogenase activity
JCM10941_03570	COG0033	Phosphoglucomutase
JCM10941_03600	COG1653	transport
JCM10941_03630	COG1278	Cold shock
JCM10941_03640	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
JCM10941_03650	COG1496	oxidoreductase activity
JCM10941_03660	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
JCM10941_03670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
JCM10941_03690	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JCM10941_03700	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
JCM10941_03710	COG0406	alpha-ribazole phosphatase activity
JCM10941_03720	COG1028	Short-chain dehydrogenase reductase Sdr
JCM10941_03730	COG0492	ferredoxin-NADP+ reductase activity
JCM10941_03750	COG0792	nuclease activity
JCM10941_03760	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
JCM10941_03800	COG1175	transmembrane transport
JCM10941_03810	COG0395	ABC-type sugar transport system, permease component
JCM10941_03870	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
JCM10941_03880	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
JCM10941_03890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JCM10941_03900	COG0805	protein transport
JCM10941_03910	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JCM10941_03910	COG1605	Chorismate mutase
JCM10941_03930	COG3573	Dehydrogenase
JCM10941_04030	COG1063	alcohol dehydrogenase
JCM10941_04090	COG2255	four-way junction helicase activity
JCM10941_04100	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
JCM10941_04110	COG0564	pseudouridine synthase activity
JCM10941_04140	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
JCM10941_04150	COG0232	Belongs to the dGTPase family. Type 2 subfamily
JCM10941_04160	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
JCM10941_04170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
JCM10941_04190	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
JCM10941_04200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
JCM10941_04210	COG0333	Belongs to the bacterial ribosomal protein bL32 family
JCM10941_04280	COG0778	Nitroreductase
JCM10941_04310	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JCM10941_04320	COG0131	Imidazoleglycerol-phosphate dehydratase
JCM10941_04330	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
JCM10941_04340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
JCM10941_04350	COG0517	IMP dehydrogenase activity
JCM10941_04350	COG0516	GMP reductase activity
JCM10941_04380	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
JCM10941_04410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JCM10941_04460	COG0706	membrane insertase activity
JCM10941_04470	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
JCM10941_04480	COG0594	ribonuclease P activity
JCM10941_04500	COG1022	Amp-dependent synthetase and ligase
JCM10941_04550	COG1121	(ABC) transporter
JCM10941_04560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
JCM10941_04570	COG1959	2 iron, 2 sulfur cluster binding
JCM10941_04580	COG1104	cysteine desulfurase activity
JCM10941_04590	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
JCM10941_04600	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
JCM10941_04630	COG1028	Short-chain dehydrogenase reductase Sdr
JCM10941_04670	COG0492	ferredoxin-NADP+ reductase activity
JCM10941_04680	COG3321	synthase
JCM10941_04680	COG1028	Short-chain dehydrogenase reductase Sdr
JCM10941_04680	COG0604	alcohol dehydrogenase
JCM10941_04710	COG0747	negative chemotaxis
JCM10941_04720	COG0601	transmembrane transport
JCM10941_04730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JCM10941_04760	COG0517	IMP dehydrogenase activity
JCM10941_04770	COG0123	including yeast histone deacetylase and acetoin utilization protein
JCM10941_04780	COG2104	thiamine diphosphate biosynthetic process
JCM10941_04790	COG0037	tRNA processing
JCM10941_04820	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
JCM10941_04840	COG0366	Alpha amylase catalytic
JCM10941_04850	COG2226	methyltransferase
JCM10941_04860	COG2226	methyltransferase
JCM10941_04870	COG0815	Transfers the fatty acyl group on membrane lipoproteins
JCM10941_04890	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
JCM10941_04900	COG3744	PilT protein domain protein
JCM10941_04920	COG0460	homoserine dehydrogenase
JCM10941_04940	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
JCM10941_05000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
JCM10941_05040	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
JCM10941_05060	COG0247	lactate metabolic process
JCM10941_05070	COG0277	FAD linked oxidase domain protein
JCM10941_05080	COG0277	FAD linked oxidase domain protein
JCM10941_05090	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
JCM10941_05100	COG1414	Transcriptional regulator
JCM10941_05110	COG0789	Transcriptional regulator
JCM10941_05130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JCM10941_05140	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
JCM10941_05210	COG0861	Integral membrane protein TerC family
JCM10941_05230	COG2151	metal-sulfur cluster biosynthetic enzyme
JCM10941_05240	COG0281	malic enzyme
JCM10941_05270	COG0404	The glycine cleavage system catalyzes the degradation of glycine
JCM10941_05280	COG0509	glycine decarboxylation via glycine cleavage system
JCM10941_05290	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JCM10941_05300	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
JCM10941_05310	COG0196	riboflavin kinase activity
JCM10941_05360	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
JCM10941_05370	COG2813	Specifically methylates the guanine in position
JCM10941_05380	COG0527	aspartate kinase activity
JCM10941_05440	COG4956	integral membrane protein (PIN domain superfamily)
JCM10941_05450	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
JCM10941_05460	COG0542	response to heat
JCM10941_05470	COG0423	glycine-tRNA ligase activity
JCM10941_05500	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
JCM10941_05540	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
JCM10941_05540	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JCM10941_05560	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
JCM10941_05580	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
JCM10941_05600	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JCM10941_05610	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JCM10941_05620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
JCM10941_05630	COG0114	fumarate hydratase activity
JCM10941_05640	COG0183	Belongs to the thiolase family
JCM10941_05670	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
JCM10941_05680	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
JCM10941_05710	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
JCM10941_05720	COG1254	Belongs to the acylphosphatase family
JCM10941_05750	COG1063	alcohol dehydrogenase
JCM10941_05760	COG2133	pyrroloquinoline quinone binding
JCM10941_05780	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
JCM10941_05790	COG0154	amidase activity
JCM10941_05840	COG0572	uridine kinase
JCM10941_05850	COG3842	ATPase activity
JCM10941_05880	COG4475	Protein of unknown function (DUF436)
JCM10941_05990	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JCM10941_06000	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
JCM10941_06010	COG0803	Belongs to the bacterial solute-binding protein 9 family
JCM10941_06040	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
JCM10941_06050	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
JCM10941_06060	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
JCM10941_06070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
JCM10941_06090	COG0318	PFAM AMP-dependent synthetase and ligase
JCM10941_06110	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
JCM10941_06120	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
JCM10941_06130	COG1293	RNA-binding protein homologous to eukaryotic snRNP
JCM10941_06140	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
JCM10941_06160	COG3870	Protein conserved in bacteria
JCM10941_06170	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
JCM10941_06190	COG0544	peptidyl-prolyl cis-trans isomerase activity
JCM10941_06200	COG0740	serine-type endopeptidase activity
JCM10941_06210	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
JCM10941_06220	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
JCM10941_06230	COG1410	methionine synthase
JCM10941_06230	COG0646	methionine synthase
JCM10941_06250	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JCM10941_06300	COG1692	metallophosphoesterase
JCM10941_06310	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
JCM10941_06320	COG1970	mechanosensitive ion channel activity
JCM10941_06330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
JCM10941_06350	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
JCM10941_06360	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
JCM10941_06470	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
JCM10941_06530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JCM10941_06570	COG0489	protein tyrosine kinase activity
JCM10941_06590	COG2264	protein methyltransferase activity
JCM10941_06600	COG1385	rRNA (uridine-N3-)-methyltransferase activity
JCM10941_06660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JCM10941_06660	COG0574	Belongs to the PEP-utilizing enzyme family
JCM10941_06680	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
JCM10941_06690	COG2046	Belongs to the sulfate adenylyltransferase family
JCM10941_06710	COG0730	response to heat
JCM10941_06720	COG0175	sulfate reduction
JCM10941_06730	COG1648	precorrin-2 dehydrogenase activity
JCM10941_06730	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JCM10941_06740	COG1587	Uroporphyrinogen-III synthase
JCM10941_06750	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
JCM10941_06770	COG0352	thiamine-phosphate diphosphorylase activity
JCM10941_06780	COG2104	thiamine diphosphate biosynthetic process
JCM10941_06790	COG2022	thiamine diphosphate biosynthetic process
JCM10941_06800	COG2022	thiamine diphosphate biosynthetic process
JCM10941_06800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JCM10941_06810	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
JCM10941_06820	COG0477	Major facilitator Superfamily
JCM10941_06830	COG0351	phosphomethylpyrimidine kinase
JCM10941_06890	COG1175	transmembrane transport
JCM10941_06910	COG1940	carbohydrate kinase activity
JCM10941_06920	COG0183	Belongs to the thiolase family
JCM10941_06950	COG1028	Short-chain dehydrogenase reductase Sdr
JCM10941_06990	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JCM10941_06990	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
JCM10941_07010	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
JCM10941_07030	COG0195	Participates in both transcription termination and antitermination
JCM10941_07040	COG0779	Required for maturation of 30S ribosomal subunits
JCM10941_07050	COG0739	heme binding
JCM10941_07060	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
JCM10941_07070	COG0640	Transcriptional regulator
JCM10941_07080	COG2217	Heavy metal translocating P-type atpase
JCM10941_07090	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
JCM10941_07100	COG0017	Asparaginyl-tRNA synthetase
JCM10941_07110	COG0561	phosphatase activity
JCM10941_07120	COG0384	phenazine biosynthesis protein PhzF
JCM10941_07140	COG0124	histidyl-tRNA synthetase
JCM10941_07160	COG3842	ATPase activity
JCM10941_07190	COG1573	uracil-dna glycosylase
JCM10941_07230	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
JCM10941_07240	COG0519	Catalyzes the synthesis of GMP from XMP
JCM10941_07240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JCM10941_07260	COG1316	TRANSCRIPTIONal
JCM10941_07270	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
JCM10941_07360	COG0295	cytidine deaminase activity
JCM10941_07380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JCM10941_07400	COG1760	l-serine dehydratase
JCM10941_07420	COG0481	GTPase activity
JCM10941_07440	COG0463	Glycosyl transferase, family 2
JCM10941_07480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JCM10941_07510	COG1028	Short-chain dehydrogenase reductase Sdr
JCM10941_07560	COG0405	Gamma-glutamyltransferase
JCM10941_07570	COG1073	alpha beta
JCM10941_07600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
JCM10941_07610	COG2873	o-acetylhomoserine
JCM10941_07640	COG1063	alcohol dehydrogenase
JCM10941_07660	COG3191	aminopeptidase activity
JCM10941_07670	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
JCM10941_07690	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JCM10941_07700	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
JCM10941_07710	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JCM10941_07800	COG0167	dihydroorotate dehydrogenase activity
JCM10941_07820	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
JCM10941_07830	COG0540	Belongs to the ATCase OTCase family
JCM10941_07840	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
JCM10941_07860	COG0730	response to heat
JCM10941_07870	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
JCM10941_07890	COG1960	acyl-CoA dehydrogenase activity
JCM10941_07900	COG0456	acetyltransferase
JCM10941_07920	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
JCM10941_07930	COG0009	L-threonylcarbamoyladenylate synthase
JCM10941_07940	COG1459	type II secretion system
JCM10941_07970	COG0277	FAD linked oxidase domain protein
JCM10941_07990	COG0287	Prephenate dehydrogenase
JCM10941_08000	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
JCM10941_08010	COG2514	catechol 2,3-dioxygenase activity
JCM10941_08020	COG2353	YceI-like domain
JCM10941_08030	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
JCM10941_08040	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
JCM10941_08070	COG1609	Transcriptional regulator
JCM10941_08080	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JCM10941_08090	COG0179	Fumarylacetoacetate (FAA) hydrolase
JCM10941_08110	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
JCM10941_08120	COG0151	Belongs to the GarS family
JCM10941_08130	COG2176	DNA-directed DNA polymerase activity
JCM10941_08130	COG5002	protein histidine kinase activity
JCM10941_08190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
JCM10941_08210	COG0217	transcriptional regulatory protein
JCM10941_08220	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
JCM10941_08220	COG4651	solute:proton antiporter activity
JCM10941_08230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
JCM10941_08240	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
JCM10941_08250	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JCM10941_08260	COG1674	ftsk spoiiie
JCM10941_08290	COG0517	IMP dehydrogenase activity
JCM10941_08310	COG3620	sequence-specific DNA binding
JCM10941_08310	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JCM10941_08310	COG0617	tRNA 3'-terminal CCA addition
JCM10941_08330	COG1994	Peptidase M50
JCM10941_08340	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
JCM10941_08360	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JCM10941_08390	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
JCM10941_08410	COG2719	SpoVR family
JCM10941_08420	COG2718	Belongs to the UPF0229 family
JCM10941_08430	COG2766	serine protein kinase
JCM10941_08480	COG2137	regulation of response to DNA damage stimulus
JCM10941_08500	COG2359	stage V sporulation protein S
JCM10941_08510	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JCM10941_08520	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
JCM10941_08540	COG0463	Glycosyl transferase, family 2
JCM10941_08550	COG0750	zinc metalloprotease
JCM10941_08560	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
JCM10941_08570	COG4589	Belongs to the CDS family
JCM10941_08580	COG0233	cytoplasmic translational termination
JCM10941_08590	COG0528	UMP kinase activity
JCM10941_08600	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
JCM10941_08610	COG0052	Belongs to the universal ribosomal protein uS2 family
JCM10941_08620	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
JCM10941_08630	COG0494	nUDIX hydrolase
JCM10941_08710	COG0402	S-adenosylhomocysteine deaminase activity
JCM10941_08730	COG4948	Mandelate Racemase Muconate Lactonizing
JCM10941_08740	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
JCM10941_08750	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
JCM10941_08760	COG1811	Na channel or pump
JCM10941_08770	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
JCM10941_08770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JCM10941_08800	COG1215	transferase activity, transferring glycosyl groups
JCM10941_08840	COG1215	transferase activity, transferring glycosyl groups
JCM10941_08860	COG0438	transferase activity, transferring glycosyl groups
JCM10941_08870	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
JCM10941_08890	COG1250	3-hydroxyacyl-CoA dehydrogenase
JCM10941_08890	COG1024	Enoyl-CoA hydratase
JCM10941_08900	COG0183	Belongs to the thiolase family
JCM10941_08910	COG1960	acyl-CoA dehydrogenase activity
JCM10941_08920	COG0215	cysteine-tRNA ligase activity
JCM10941_08930	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
JCM10941_08950	COG2738	Putative neutral zinc metallopeptidase
JCM10941_08980	COG1196	nuclear chromosome segregation
JCM10941_09010	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
JCM10941_09020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JCM10941_09020	COG3153	acetyltransferase
JCM10941_09030	COG1268	BioY protein
JCM10941_09050	COG0126	phosphoglycerate kinase activity
JCM10941_09060	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
JCM10941_09070	COG0824	Thioesterase
JCM10941_09090	COG0557	exoribonuclease II activity
JCM10941_09110	COG1355	regulation of microtubule-based process
JCM10941_09120	COG1353	crispr-associated protein
JCM10941_09120	COG0617	tRNA 3'-terminal CCA addition
JCM10941_09130	COG0237	dephospho-CoA kinase activity
JCM10941_09150	COG0742	ribosomal rna small subunit methyltransferase
JCM10941_09160	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
JCM10941_09170	COG0138	bifunctional purine biosynthesis protein purh
JCM10941_09180	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
JCM10941_09210	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
JCM10941_09340	COG0149	triose-phosphate isomerase activity
JCM10941_09350	COG3239	Fatty acid desaturase
JCM10941_09360	COG1490	D-aminoacyl-tRNA deacylase activity
JCM10941_09370	COG1307	EDD domain protein, DegV family
JCM10941_09380	COG1307	EDD domain protein, DegV family
JCM10941_09390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
JCM10941_09400	COG1510	regulation of RNA biosynthetic process
JCM10941_09420	COG3769	mannosylglycerate metabolic process
JCM10941_09440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
JCM10941_09460	COG1012	belongs to the aldehyde dehydrogenase family
JCM10941_09470	COG2368	4-hydroxyphenylacetate
JCM10941_09480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
JCM10941_09520	COG2050	protein possibly involved in aromatic compounds catabolism
JCM10941_09530	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
JCM10941_09550	COG2030	dehydratase
JCM10941_09550	COG1012	belongs to the aldehyde dehydrogenase family
JCM10941_09590	COG3396	Phenylacetate-CoA oxygenase
JCM10941_09610	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
JCM10941_09630	COG0395	ABC-type sugar transport system, permease component
JCM10941_09670	COG1980	fructose-bisphosphate aldolase activity
JCM10941_09680	COG1733	regulation of RNA biosynthetic process
JCM10941_09690	COG2193	ferroxidase activity
JCM10941_09700	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
JCM10941_09710	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
JCM10941_09730	COG1331	Highly conserved protein containing a thioredoxin domain
JCM10941_09740	COG0183	Belongs to the thiolase family
JCM10941_09750	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
JCM10941_09820	COG1012	belongs to the aldehyde dehydrogenase family
JCM10941_09830	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
JCM10941_09880	COG0745	RESPONSE REGULATOR receiver
JCM10941_09890	COG2205	protein histidine kinase activity
JCM10941_09920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
JCM10941_09930	COG1136	(ABC) transporter
JCM10941_09940	COG0577	efflux transmembrane transporter activity
JCM10941_09940	COG1136	(ABC) transporter
JCM10941_10060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
JCM10941_10130	COG0582	viral genome integration into host DNA
JCM10941_10140	COG2897	thiosulfate sulfurtransferase activity
JCM10941_10150	COG1760	l-serine dehydratase
JCM10941_10160	COG2197	response regulator
JCM10941_10170	COG0335	large ribosomal subunit rRNA binding
JCM10941_10180	COG0336	Belongs to the RNA methyltransferase TrmD family
JCM10941_10190	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
JCM10941_10200	COG1837	Belongs to the UPF0109 family
JCM10941_10210	COG0228	four-way junction DNA binding
JCM10941_10240	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JCM10941_10250	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JCM10941_10250	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JCM10941_10260	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
JCM10941_10280	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
JCM10941_10300	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
JCM10941_10310	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
JCM10941_10320	COG1702	phosphate starvation-inducible protein PhoH
JCM10941_10340	COG4864	UPF0365 protein
JCM10941_10360	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
JCM10941_10400	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JCM10941_10400	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
JCM10941_10420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
JCM10941_10440	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
JCM10941_10450	COG1397	ADP-ribosylglycohydrolase
JCM10941_10460	COG2239	Acts as a magnesium transporter
JCM10941_10480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JCM10941_10480	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
JCM10941_10500	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JCM10941_10500	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
JCM10941_10510	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
JCM10941_10520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
JCM10941_10530	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
JCM10941_10540	COG0006	proline dipeptidase activity
JCM10941_10560	COG0739	heme binding
JCM10941_10580	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
JCM10941_10590	COG0254	rRNA binding
JCM10941_10610	COG2001	Belongs to the MraZ family
JCM10941_10620	COG0275	rRNA processing
JCM10941_10640	COG0768	penicillin binding
JCM10941_10650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
JCM10941_10670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JCM10941_10680	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
JCM10941_10690	COG0772	Belongs to the SEDS family
JCM10941_10700	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
JCM10941_10710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
JCM10941_10720	COG0812	UDP-N-acetylmuramate dehydrogenase activity
JCM10941_10760	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
JCM10941_10780	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
JCM10941_10800	COG0159	tryptophan synthase activity
JCM10941_10810	COG0133	tryptophan synthase activity
JCM10941_10820	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
JCM10941_10830	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
JCM10941_10840	COG1744	ABC transporter substrate-binding protein PnrA-like
JCM10941_10850	COG3845	ABC transporter
JCM10941_10950	COG0438	transferase activity, transferring glycosyl groups
JCM10941_10960	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
JCM10941_10980	COG0039	L-malate dehydrogenase activity
JCM10941_10990	COG2819	hydrolase of the alpha beta superfamily
JCM10941_11000	COG0861	Integral membrane protein TerC family
JCM10941_11020	COG0247	lactate metabolic process
JCM10941_11020	COG2181	nitrate reductase activity
JCM10941_11040	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
JCM10941_11050	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
JCM10941_11060	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
JCM10941_11080	COG0439	Biotin carboxylase
JCM10941_11090	COG0511	ligase activity, forming carbon-carbon bonds
JCM10941_11100	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
JCM10941_11140	COG0010	Belongs to the arginase family
JCM10941_11170	COG1100	Small GTP-binding protein
JCM10941_11190	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
JCM10941_11200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
JCM10941_11220	COG2814	Major facilitator Superfamily
JCM10941_11230	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
JCM10941_11240	COG1185	polyribonucleotide nucleotidyltransferase activity
JCM10941_11250	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
JCM10941_11270	COG0745	RESPONSE REGULATOR receiver
JCM10941_11280	COG5002	protein histidine kinase activity
JCM10941_11290	COG1960	acyl-CoA dehydrogenase activity
JCM10941_11300	COG2086	electron transfer activity
JCM10941_11310	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
JCM10941_11330	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JCM10941_11340	COG1573	uracil-dna glycosylase
JCM10941_11350	COG1796	DNA polymerase
JCM10941_11350	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
JCM10941_11380	COG2309	aminopeptidase activity
JCM10941_11420	COG2873	o-acetylhomoserine
JCM10941_11430	COG2358	TRAP transporter, solute receptor (TAXI family
JCM10941_11450	COG1126	abc transporter atp-binding protein
JCM10941_11470	COG1752	Esterase of the alpha-beta hydrolase superfamily
JCM10941_11480	COG3311	Transcriptional regulator
JCM10941_11500	COG0134	indole-3-glycerol-phosphate synthase activity
JCM10941_11510	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
JCM10941_11530	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
JCM10941_11560	COG0765	amino acid transport
JCM10941_11570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
JCM10941_11590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
JCM10941_11600	COG0569	domain protein
JCM10941_11610	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JCM10941_11620	COG1426	Protein conserved in bacteria
JCM10941_11630	COG2313	pseudouridylate synthase activity
JCM10941_11650	COG3001	Fructosamine kinase
JCM10941_11660	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JCM10941_11680	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
JCM10941_11710	COG0012	GTP binding
JCM10941_11720	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
JCM10941_11740	COG0424	maF-like protein
JCM10941_11770	COG0768	penicillin binding
JCM10941_11790	COG2322	membrane
JCM10941_11820	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
JCM10941_11830	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JCM10941_11850	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
JCM10941_11890	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
JCM10941_11910	COG1131	(ABC) transporter
JCM10941_11940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JCM10941_11970	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
JCM10941_11980	COG0440	acetolactate synthase activity
JCM10941_11990	COG0028	Belongs to the TPP enzyme family
JCM10941_12000	COG0492	ferredoxin-NADP+ reductase activity
JCM10941_12010	COG4970	Tfp pilus assembly protein FimT
JCM10941_12060	COG2165	general secretion pathway protein
JCM10941_12120	COG0180	Tryptophanyl-tRNA synthetase
JCM10941_12130	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JCM10941_12140	COG0066	3-isopropylmalate dehydratase activity
JCM10941_12150	COG0473	3-isopropylmalate dehydrogenase activity
JCM10941_12180	COG0300	oxidoreductase activity
JCM10941_12190	COG0129	dihydroxy-acid dehydratase activity
JCM10941_12210	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
JCM10941_12220	COG1177	transmembrane transport
JCM10941_12230	COG1176	ABC-type spermidine putrescine transport system, permease component I
JCM10941_12240	COG3842	ATPase activity
JCM10941_12250	COG0772	Belongs to the SEDS family
JCM10941_12260	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
JCM10941_12270	COG2894	cell division
JCM10941_12280	COG1733	regulation of RNA biosynthetic process
JCM10941_12300	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JCM10941_12300	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
JCM10941_12320	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JCM10941_12330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JCM10941_12340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JCM10941_12350	COG0653	protein targeting
JCM10941_12360	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
JCM10941_12400	COG0393	Putative heavy-metal-binding
JCM10941_12410	COG1111	helicase
JCM10941_12410	COG1205	dead DEAH box helicase
JCM10941_12440	COG0358	DNA primase activity
JCM10941_12460	COG1250	3-hydroxyacyl-CoA dehydrogenase
JCM10941_12470	COG0612	Peptidase, M16
JCM10941_12480	COG0612	Peptidase, M16
JCM10941_12490	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
JCM10941_12540	COG1394	ATPase activity, coupled to movement of substances
JCM10941_12550	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
JCM10941_12560	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
JCM10941_12570	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
JCM10941_12580	COG1527	subunit (C
JCM10941_12590	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
JCM10941_12610	COG1269	ATP hydrolysis coupled proton transport
JCM10941_12660	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JCM10941_12680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
JCM10941_12710	COG0419	ATPase involved in DNA repair
JCM10941_12720	COG0420	3'-5' exonuclease activity
JCM10941_12760	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
JCM10941_12770	COG2884	Cell division ATP-binding protein ftsE
JCM10941_12780	COG0793	Belongs to the peptidase S41A family
JCM10941_12800	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JCM10941_12800	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
JCM10941_12810	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
JCM10941_12820	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
JCM10941_12840	COG1079	Belongs to the binding-protein-dependent transport system permease family
JCM10941_12850	COG4603	Belongs to the binding-protein-dependent transport system permease family
JCM10941_12860	COG1129	ABC transporter
JCM10941_12870	COG0746	molybdenum cofactor guanylyltransferase activity
JCM10941_12890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JCM10941_12930	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
JCM10941_12940	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
JCM10941_12950	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
JCM10941_12970	COG1994	Peptidase M50
JCM10941_12970	COG0517	IMP dehydrogenase activity
JCM10941_12990	COG2358	TRAP transporter, solute receptor (TAXI family
JCM10941_13030	COG0788	formyltetrahydrofolate deformylase activity
JCM10941_13040	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
JCM10941_13050	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
JCM10941_13060	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
JCM10941_13100	COG0737	Belongs to the 5'-nucleotidase family
JCM10941_13110	COG0174	glutamine synthetase
JCM10941_13130	COG0559	Belongs to the binding-protein-dependent transport system permease family
JCM10941_13170	COG0747	negative chemotaxis
JCM10941_13180	COG0601	transmembrane transport
JCM10941_13190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JCM10941_13210	COG0285	dihydrofolate synthase activity
JCM10941_13220	COG1132	(ABC) transporter
JCM10941_13230	COG1132	(ABC) transporter
JCM10941_13240	COG0372	Belongs to the citrate synthase family
JCM10941_13250	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
JCM10941_13260	COG1482	cell wall glycoprotein biosynthetic process
JCM10941_13280	COG1515	deoxyribonuclease V activity
JCM10941_13300	COG0776	regulation of translation
JCM10941_13330	COG2197	response regulator
JCM10941_13340	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
JCM10941_13350	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
JCM10941_13360	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
JCM10941_13370	COG1324	tolerance protein
JCM10941_13400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JCM10941_13440	COG2205	protein histidine kinase activity
JCM10941_13460	COG0247	lactate metabolic process
JCM10941_13470	COG1139	Iron-sulfur cluster binding protein
JCM10941_13480	COG1556	Lactate utilization protein
JCM10941_13500	COG1752	Esterase of the alpha-beta hydrolase superfamily
JCM10941_13510	COG2815	serine threonine protein kinase
JCM10941_13510	COG0515	serine threonine protein kinase
JCM10941_13530	COG0860	N-Acetylmuramoyl-L-alanine amidase
JCM10941_13550	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
JCM10941_13590	COG0473	3-isopropylmalate dehydrogenase activity
JCM10941_13640	COG1450	Type ii and iii secretion system protein
JCM10941_13650	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
JCM10941_13660	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
JCM10941_13670	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
JCM10941_13680	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
JCM10941_13680	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
JCM10941_13690	COG0736	holo-[acyl-carrier-protein] synthase activity
JCM10941_13720	COG1160	GTP binding
JCM10941_13730	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
JCM10941_13740	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
JCM10941_13740	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
JCM10941_13750	COG0083	homoserine kinase activity
JCM10941_13770	COG0268	Binds directly to 16S ribosomal RNA
JCM10941_13790	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
JCM10941_13800	COG0723	plastoquinol--plastocyanin reductase activity
JCM10941_13820	COG3088	subunit of a heme lyase
JCM10941_13820	COG4235	cytochrome complex assembly
JCM10941_13830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JCM10941_13840	COG1138	Cytochrome C-type biogenesis protein
JCM10941_13850	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
JCM10941_13860	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JCM10941_13870	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
JCM10941_13880	COG4133	protoheme IX ABC transporter activity
JCM10941_13890	COG0785	Cytochrome C biogenesis protein
JCM10941_13900	COG3258	Cytochrome c
JCM10941_13920	COG0446	pyridine nucleotide-disulphide oxidoreductase
JCM10941_13950	COG3258	Cytochrome c
JCM10941_13960	COG2010	Cytochrome c
JCM10941_13970	COG0737	Belongs to the 5'-nucleotidase family
JCM10941_13980	COG2010	Cytochrome c
JCM10941_13990	COG3258	Cytochrome c
JCM10941_14030	COG2010	Cytochrome c
JCM10941_14040	COG3842	ATPase activity
JCM10941_14100	COG0318	PFAM AMP-dependent synthetase and ligase
JCM10941_14110	COG3360	Dodecin
JCM10941_14140	COG1024	Enoyl-CoA hydratase
JCM10941_14150	COG0813	purine-nucleoside phosphorylase activity
JCM10941_14160	COG1136	(ABC) transporter
JCM10941_14170	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
JCM10941_14180	COG2045	Belongs to the ComB family
JCM10941_14200	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
JCM10941_14220	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
JCM10941_14240	COG0107	imidazoleglycerol-phosphate synthase activity
JCM10941_14250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
JCM10941_14250	COG0140	phosphoribosyl-ATP diphosphatase activity
JCM10941_14260	COG1494	fructose-1,6-bisphosphatase
JCM10941_14270	COG0686	Belongs to the AlaDH PNT family
JCM10941_14280	COG0427	acetyl-CoA hydrolase
JCM10941_14290	COG0084	hydrolase, TatD family'
JCM10941_14300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
JCM10941_14320	COG0017	Asparaginyl-tRNA synthetase
JCM10941_14330	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
JCM10941_14360	COG2009	succinate dehydrogenase
JCM10941_14370	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
JCM10941_14430	COG0318	PFAM AMP-dependent synthetase and ligase
JCM10941_14440	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
JCM10941_14450	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
JCM10941_14460	COG0504	CTP synthase activity
JCM10941_14480	COG0067	glutamate synthase
JCM10941_14480	COG0069	glutamate synthase activity
JCM10941_14480	COG0070	glutamate synthase
JCM10941_14500	COG0840	transmembrane signaling receptor activity
JCM10941_14510	COG0305	Participates in initiation and elongation during chromosome replication
JCM10941_14530	COG0475	glutathione-regulated potassium exporter activity
JCM10941_14540	COG0517	IMP dehydrogenase activity
JCM10941_14540	COG0617	tRNA 3'-terminal CCA addition
JCM10941_14540	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
JCM10941_14570	COG0475	glutathione-regulated potassium exporter activity
JCM10941_14580	COG0490	domain, Protein
JCM10941_14620	COG3118	belongs to the thioredoxin family
JCM10941_14680	COG0542	response to heat
JCM10941_14690	COG0789	Transcriptional regulator
JCM10941_14700	COG0484	heat shock protein binding
JCM10941_14710	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
JCM10941_14720	COG0443	Heat shock 70 kDa protein
JCM10941_14730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
JCM10941_14740	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
JCM10941_14750	COG0616	signal peptide processing
JCM10941_14780	COG1310	metal-dependent protease of the Pad1 Jab1 superfamily
JCM10941_14790	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
JCM10941_14800	COG0714	Associated with various cellular activities
JCM10941_14810	COG0574	Belongs to the PEP-utilizing enzyme family
JCM10941_14810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
JCM10941_14820	COG1272	protein, Hemolysin III
JCM10941_14840	COG3850	Histidine kinase
JCM10941_14840	COG5002	protein histidine kinase activity
JCM10941_14870	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
JCM10941_14900	COG1011	Hydrolase
JCM10941_14940	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
JCM10941_14960	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
JCM10941_14980	COG0047	phosphoribosylformylglycinamidine synthase activity
JCM10941_15000	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
JCM10941_15010	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
JCM10941_15020	COG0116	Belongs to the methyltransferase superfamily
JCM10941_15050	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
JCM10941_15060	COG0497	DNA recombination
JCM10941_15080	COG0604	alcohol dehydrogenase
JCM10941_15120	COG0585	pseudouridine synthase activity
JCM10941_15150	COG0557	exoribonuclease II activity
JCM10941_15160	COG0473	3-isopropylmalate dehydrogenase activity
JCM10941_15170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JCM10941_15200	COG4974	Belongs to the 'phage' integrase family
JCM10941_15240	COG0037	tRNA processing
JCM10941_15240	COG0590	tRNA wobble adenosine to inosine editing
JCM10941_15280	COG2050	protein possibly involved in aromatic compounds catabolism
JCM10941_15300	COG0322	excinuclease ABC activity
JCM10941_15310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JCM10941_15320	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
JCM10941_15330	COG1854	S-ribosylhomocysteine lyase activity
JCM10941_15340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
JCM10941_15340	COG0519	Catalyzes the synthesis of GMP from XMP
JCM10941_15350	COG4636	protein conserved in cyanobacteria
JCM10941_15360	COG4274	PFAM GYD family protein
JCM10941_15370	COG0346	lactoylglutathione lyase activity
JCM10941_15380	COG0328	RNA-DNA hybrid ribonuclease activity
JCM10941_15390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
JCM10941_15400	COG2095	MarC family integral membrane protein
JCM10941_15410	COG1438	arginine binding
JCM10941_15420	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
JCM10941_15430	COG1758	RNA polymerase activity
JCM10941_15440	COG0194	GDP metabolic process
JCM10941_15460	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
JCM10941_15470	COG2385	sporulation resulting in formation of a cellular spore
JCM10941_15480	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
JCM10941_15500	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
JCM10941_15580	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JCM10941_15590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
JCM10941_15600	COG1012	belongs to the aldehyde dehydrogenase family
JCM10941_15610	COG0506	proline dehydrogenase activity
JCM10941_15640	COG0156	8-amino-7-oxononanoate synthase activity
JCM10941_15650	COG0827	DNA restriction-modification system
JCM10941_15650	COG0732	type I restriction modification DNA specificity domain
JCM10941_15680	COG0187	DNA topoisomerase II activity
JCM10941_15690	COG1181	Belongs to the D-alanine--D-alanine ligase family
JCM10941_15700	COG0193	aminoacyl-tRNA hydrolase activity
JCM10941_15710	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
JCM10941_15760	COG2815	serine threonine protein kinase
JCM10941_15760	COG0515	serine threonine protein kinase
JCM10941_15770	COG0631	protein serine/threonine phosphatase activity
JCM10941_15790	COG2814	Major facilitator Superfamily
JCM10941_15800	COG0113	porphobilinogen synthase activity
JCM10941_15810	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
JCM10941_15820	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
JCM10941_15870	COG4946	Tricorn protease homolog
JCM10941_15870	COG0823	Involved in the tonB-independent uptake of proteins
JCM10941_15870	COG1506	peptidase
JCM10941_15880	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
JCM10941_15890	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
JCM10941_15930	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
JCM10941_15940	COG1011	Hydrolase
JCM10941_15990	COG0537	adenosine 5'-monophosphoramidase activity
JCM10941_16000	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
JCM10941_16010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
JCM10941_16020	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
JCM10941_16030	COG0071	Belongs to the small heat shock protein (HSP20) family
JCM10941_16040	COG2897	thiosulfate sulfurtransferase activity
JCM10941_16050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
JCM10941_16070	COG1764	response to oxidative stress
JCM10941_16120	COG3842	ATPase activity
JCM10941_16130	COG0101	tRNA pseudouridine synthase activity
JCM10941_16140	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
JCM10941_16150	COG0601	transmembrane transport
JCM10941_16160	COG0747	negative chemotaxis
JCM10941_16180	COG0006	proline dipeptidase activity
JCM10941_16190	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
JCM10941_16220	COG1166	arginine decarboxylase activity
JCM10941_16230	COG3706	GGDEF domain
JCM10941_16240	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
JCM10941_16250	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
JCM10941_16260	COG1611	Belongs to the LOG family
JCM10941_16270	COG1193	negative regulation of DNA recombination
JCM10941_16290	COG0366	Alpha amylase catalytic
JCM10941_16360	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
JCM10941_16370	COG0142	geranyltranstransferase activity
JCM10941_16390	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
JCM10941_16450	COG0203	ribosomal protein L17
JCM10941_16460	COG0202	RNA polymerase activity
JCM10941_16470	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
JCM10941_16480	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
JCM10941_16490	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
JCM10941_16500	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
JCM10941_16520	COG0563	adenylate kinase activity
JCM10941_16530	COG0201	protein transport
JCM10941_16580	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
JCM10941_16590	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
JCM10941_16600	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
JCM10941_16630	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
JCM10941_16640	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
JCM10941_16650	COG0255	Belongs to the universal ribosomal protein uL29 family
JCM10941_16660	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
JCM10941_16670	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
JCM10941_16690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
JCM10941_16700	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
JCM10941_16710	COG0089	rRNA binding
JCM10941_16720	COG0088	Forms part of the polypeptide exit tunnel
JCM10941_16740	COG0051	transcription antitermination factor activity, RNA binding
JCM10941_16770	COG0049	tRNA binding
JCM10941_16800	COG0442	prolyl-tRNA aminoacylation
JCM10941_16840	COG1115	amino acid carrier protein
JCM10941_16880	COG1489	DNA binding
JCM10941_16910	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
JCM10941_16940	COG0432	Pfam Uncharacterised protein family UPF0047
JCM10941_16950	COG3253	May function as heme-dependent peroxidase
JCM10941_16960	COG0668	transmembrane transport
JCM10941_16980	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
JCM10941_16990	COG2217	Heavy metal translocating P-type atpase
JCM10941_17030	COG0745	RESPONSE REGULATOR receiver
JCM10941_17040	COG2205	protein histidine kinase activity
JCM10941_17090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
JCM10941_17100	COG2226	methyltransferase
JCM10941_17160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
JCM10941_17170	COG0822	iron-sulfur transferase activity
JCM10941_17210	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
JCM10941_17230	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
JCM10941_17240	COG0284	orotidine-5'-phosphate decarboxylase activity
JCM10941_17260	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
JCM10941_17280	COG0416	fatty acid biosynthetic process
JCM10941_17290	COG3118	belongs to the thioredoxin family
JCM10941_17300	COG1185	polyribonucleotide nucleotidyltransferase activity
JCM10941_17310	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
JCM10941_17330	COG0438	transferase activity, transferring glycosyl groups
JCM10941_17370	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
JCM10941_17390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
JCM10941_17400	COG3706	GGDEF domain
JCM10941_17460	COG0437	4 iron, 4 sulfur cluster binding
JCM10941_17490	COG0825	malonyl-CoA metabolic process
JCM10941_17500	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
JCM10941_17570	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
JCM10941_17620	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
JCM10941_17630	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
JCM10941_17640	COG0211	Belongs to the bacterial ribosomal protein bL27 family
JCM10941_17650	COG0261	This protein binds to 23S rRNA in the presence of protein L20
JCM10941_17710	COG0315	cyclic pyranopterin monophosphate synthase activity
JCM10941_17730	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
JCM10941_17760	COG1694	Mazg nucleotide pyrophosphohydrolase
JCM10941_17770	COG1803	Methylglyoxal synthase
JCM10941_17790	COG0301	tRNA thio-modification
JCM10941_17800	COG0154	amidase activity
JCM10941_17810	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
JCM10941_17860	COG2154	pterin-4-alpha-carbinolamine dehydratase
JCM10941_17870	COG1607	acyl-coa hydrolase
JCM10941_17890	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
JCM10941_17900	COG4149	molybdate abc transporter
JCM10941_17910	COG1840	ABC-type Fe3 transport system, periplasmic component
JCM10941_17940	COG0235	Class ii aldolase
JCM10941_17950	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
JCM10941_17960	COG0085	RNA polymerase activity
JCM10941_17980	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
JCM10941_17990	COG1077	Cell shape determining protein MreB Mrl
JCM10941_18000	COG1418	mRNA catabolic process
JCM10941_18000	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
JCM10941_18010	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
JCM10941_18020	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
JCM10941_18030	COG1058	Belongs to the CinA family
JCM10941_18030	COG1546	Belongs to the CinA family
JCM10941_18040	COG0354	folic acid binding
JCM10941_18070	COG4948	Mandelate Racemase Muconate Lactonizing
JCM10941_18100	COG1175	transmembrane transport
JCM10941_18120	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
JCM10941_18140	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
JCM10941_18160	COG0577	efflux transmembrane transporter activity
JCM10941_18160	COG1136	(ABC) transporter
JCM10941_18170	COG4181	ATPase activity
JCM10941_18180	COG0446	pyridine nucleotide-disulphide oxidoreductase
JCM10941_18210	COG0396	ATPase activity
JCM10941_18220	COG0719	Fe-S assembly protein
JCM10941_18230	COG0719	Fe-S assembly protein
JCM10941_18240	COG2146	nitrite reductase [NAD(P)H] activity
JCM10941_18260	COG0512	Glutamine amidotransferase of anthranilate synthase
JCM10941_18270	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
JCM10941_18350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
JCM10941_18360	COG2226	methyltransferase
JCM10941_18370	COG4603	Belongs to the binding-protein-dependent transport system permease family
JCM10941_18380	COG1079	Belongs to the binding-protein-dependent transport system permease family
JCM10941_18410	COG1774	PSP1 C-terminal conserved region
JCM10941_18420	COG0470	DNA polymerase III
JCM10941_18460	COG0497	DNA recombination
JCM10941_18560	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
JCM10941_18590	COG0302	gtp cyclohydrolase
JCM10941_18630	COG1217	gtp-binding protein TYPA
JCM10941_18650	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
JCM10941_18670	COG0395	ABC-type sugar transport system, permease component
JCM10941_18680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
JCM10941_18690	COG1131	(ABC) transporter
JCM10941_18730	COG0556	nucleotide-excision repair
JCM10941_18740	COG0497	DNA recombination
JCM10941_18770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
JCM10941_18780	COG0445	tRNA wobble uridine modification
JCM10941_18820	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
JCM10941_18820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
JCM10941_18830	COG1543	Belongs to the glycosyl hydrolase 57 family
JCM10941_18840	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JCM10941_18850	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
JCM10941_18880	COG0189	ligase activity
JCM10941_18910	COG0066	3-isopropylmalate dehydratase activity
JCM10941_18920	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
JCM10941_18950	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
JCM10941_18960	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
JCM10941_18970	COG1960	acyl-CoA dehydrogenase activity
JCM10941_18980	COG0163	prenyltransferase activity
JCM10941_19050	COG4555	ABC transporter
JCM10941_19070	COG2096	Adenosyltransferase
JCM10941_19100	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
JCM10941_19110	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
JCM10941_19130	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
JCM10941_19140	COG0723	plastoquinol--plastocyanin reductase activity
JCM10941_19190	COG1653	transport
JCM10941_19200	COG0820	rRNA (adenine-C2-)-methyltransferase activity
JCM10941_19210	COG1960	acyl-CoA dehydrogenase activity
JCM10941_19230	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
JCM10941_19270	COG0393	Putative heavy-metal-binding
JCM10941_19290	COG3956	TIGRFAM MazG family protein
JCM10941_19300	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
JCM10941_19340	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
JCM10941_19360	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
JCM10941_19370	COG1937	Protein conserved in bacteria
JCM10941_19390	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
JCM10941_19390	COG0674	pyruvate-flavodoxin oxidoreductase activity
JCM10941_19400	COG1013	pyruvate-flavodoxin oxidoreductase activity
JCM10941_19410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
JCM10941_19450	COG0205	6-phosphofructokinase activity
JCM10941_19460	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
JCM10941_19480	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
JCM10941_19510	COG0658	competence protein
JCM10941_19510	COG2333	competence protein COMEC
JCM10941_19520	COG1475	DNA binding
JCM10941_19530	COG1192	Involved in chromosome partitioning
JCM10941_19540	COG0357	Ribosomal RNA small subunit methyltransferase G
JCM10941_19640	COG1110	DNA topoisomerase II activity
JCM10941_19650	COG4565	transcriptional regulatory protein
JCM10941_19670	COG3842	ATPase activity
JCM10941_19780	COG0863	Belongs to the N(4) N(6)-methyltransferase family
JCM10941_19830	COG1857	crispr-associated protein
JCM10941_19870	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
JCM10941_19890	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
JCM10941_20000	COG1607	acyl-coa hydrolase
JCM10941_20020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
JCM10941_20090	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
JCM10941_20110	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
JCM10941_20120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
JCM10941_20130	COG4558	Periplasmic binding protein
JCM10941_20150	COG2329	Antibiotic biosynthesis monooxygenase
JCM10941_20360	COG1942	4-Oxalocrotonate Tautomerase
JCM10941_20400	COG2084	Dehydrogenase
JCM10941_20600	COG0588	phosphoglycerate mutase activity
JCM10941_20640	COG1028	Short-chain dehydrogenase reductase Sdr
JCM10941_20650	COG0318	PFAM AMP-dependent synthetase and ligase
JCM10941_20670	COG2030	dehydratase
JCM10941_20670	COG1012	belongs to the aldehyde dehydrogenase family
JCM10941_20680	COG1028	Short-chain dehydrogenase reductase Sdr
JCM10941_20700	COG1960	acyl-CoA dehydrogenase activity
JCM10941_20780	COG2211	Major facilitator Superfamily
JCM10941_20840	COG2211	Major facilitator Superfamily
JCM10941_20910	COG1797	cobyrinic acid a,c-diamide synthase activity
JCM10941_20920	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
JCM10941_20940	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
JCM10941_20970	COG0588	phosphoglycerate mutase activity
JCM10941_20980	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
JCM10941_20990	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
JCM10941_21080	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
JCM10941_21080	COG1648	precorrin-2 dehydrogenase activity
JCM10941_21090	COG0778	Nitroreductase
JCM10941_21130	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
JCM10941_21140	COG1492	cobalamin metabolic process
JCM10941_21150	COG1785	Belongs to the alkaline phosphatase family
JCM10941_21210	COG1414	Transcriptional regulator
JCM10941_21220	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
JCM10941_21240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
JCM10941_21250	COG1028	Short-chain dehydrogenase reductase Sdr
JCM10941_21280	COG1028	Short-chain dehydrogenase reductase Sdr
JCM10941_21310	COG1175	transmembrane transport
JCM10941_21350	COG2723	6-phospho-beta-galactosidase activity
JCM10941_21360	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
JCM10941_21400	COG1233	COG1233 Phytoene dehydrogenase and related
JCM10941_21410	COG0702	epimerase
JCM10941_21490	COG1562	ergosterol biosynthetic process
JCM10941_21510	COG2124	cytochrome p450
JCM10941_21580	COG1304	FMN binding
JCM10941_21620	COG1085	galactose-1-phosphate uridylyltransferase
JCM10941_21630	COG3345	alpha-galactosidase
JCM10941_21680	COG4966	pilus assembly protein PilW
JCM10941_21730	COG1475	DNA binding
JCM10941_21750	COG1475	DNA binding
JCM10941_21760	COG1192	Involved in chromosome partitioning
JCM10941_21780	COG0243	molybdopterin cofactor binding
JCM10941_21890	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
JCM10941_21910	COG2151	metal-sulfur cluster biosynthetic enzyme
JCM10941_21930	COG2814	Major facilitator Superfamily
JCM10941_21950	COG0584	glycerophosphoryl diester phosphodiesterase
JCM10941_21970	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
JCM10941_22010	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
JCM10941_22040	COG1337	RAMP superfamily
JCM10941_t00350	COG0544	peptidyl-prolyl cis-trans isomerase activity
