locus-tag	class	description
TthSNM17_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TthSNM17_00020	COG0592	DNA-directed DNA polymerase activity
TthSNM17_00030	COG0148	phosphopyruvate hydratase activity
TthSNM17_00040	COG0469	pyruvate kinase activity
TthSNM17_00060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TthSNM17_00070	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TthSNM17_00090	COG1842	Phage shock protein A
TthSNM17_00120	COG0406	alpha-ribazole phosphatase activity
TthSNM17_00130	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
TthSNM17_00140	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TthSNM17_00160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
TthSNM17_00170	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
TthSNM17_00180	COG1496	oxidoreductase activity
TthSNM17_00190	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TthSNM17_00200	COG1278	Cold shock
TthSNM17_00280	COG0033	Phosphoglucomutase
TthSNM17_00320	COG0517	IMP dehydrogenase activity
TthSNM17_00320	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
TthSNM17_00330	COG1950	PFAM Membrane protein of
TthSNM17_00340	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TthSNM17_00360	COG0181	hydroxymethylbilane synthase activity
TthSNM17_00380	COG0285	dihydrofolate synthase activity
TthSNM17_00390	COG0436	Aminotransferase
TthSNM17_00400	COG0521	Mo-molybdopterin cofactor biosynthetic process
TthSNM17_00450	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TthSNM17_00460	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TthSNM17_00470	COG1993	acr, cog1993
TthSNM17_00480	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TthSNM17_00500	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TthSNM17_00520	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
TthSNM17_00530	COG1335	isochorismatase
TthSNM17_00540	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
TthSNM17_00570	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
TthSNM17_00580	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
TthSNM17_00620	COG1660	Displays ATPase and GTPase activities
TthSNM17_00630	COG0391	Required for morphogenesis under gluconeogenic growth conditions
TthSNM17_00690	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TthSNM17_00690	COG1845	cytochrome c oxidase, subunit III
TthSNM17_00700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TthSNM17_00700	COG2010	Cytochrome c
TthSNM17_00710	COG0109	protoheme IX farnesyltransferase activity
TthSNM17_00710	COG1612	heme a metabolic process
TthSNM17_00740	COG0343	queuine tRNA-ribosyltransferase activity
TthSNM17_00750	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
TthSNM17_00760	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
TthSNM17_00810	COG1940	carbohydrate kinase activity
TthSNM17_00830	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TthSNM17_00840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TthSNM17_00850	COG0589	response to stress
TthSNM17_00860	COG1611	Belongs to the LOG family
TthSNM17_00880	COG1011	Hydrolase
TthSNM17_00890	COG0632	four-way junction helicase activity
TthSNM17_00900	COG1024	Enoyl-CoA hydratase
TthSNM17_00920	COG0508	dehydrogenase complex catalyzes the overall conversion of
TthSNM17_00940	COG1404	Belongs to the peptidase S8 family
TthSNM17_00970	COG0137	argininosuccinate synthase activity
TthSNM17_00980	COG0165	Argininosuccinate lyase
TthSNM17_01020	COG0505	Belongs to the CarA family
TthSNM17_01040	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
TthSNM17_01050	COG0166	Belongs to the GPI family
TthSNM17_01070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TthSNM17_01080	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
TthSNM17_01090	COG0459	protein refolding
TthSNM17_01100	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
TthSNM17_01110	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
TthSNM17_01130	COG0778	Nitroreductase
TthSNM17_01140	COG0791	NLP P60 protein
TthSNM17_01140	COG1388	LysM domain
TthSNM17_01160	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TthSNM17_01180	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TthSNM17_01190	COG0581	inorganic phosphate transmembrane transporter activity
TthSNM17_01200	COG0573	inorganic phosphate transmembrane transporter activity
TthSNM17_01210	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
TthSNM17_01220	COG0482	sulfurtransferase activity
TthSNM17_01240	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
TthSNM17_01250	COG0735	belongs to the Fur family
TthSNM17_01280	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TthSNM17_01290	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TthSNM17_01300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TthSNM17_01310	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TthSNM17_01320	COG0250	Participates in transcription elongation, termination and antitermination
TthSNM17_01340	COG0081	regulation of translation
TthSNM17_01360	COG0629	single-stranded DNA binding
TthSNM17_01370	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
TthSNM17_01380	COG0359	binds to the 23S rRNA
TthSNM17_01400	COG0300	oxidoreductase activity
TthSNM17_01410	COG0321	lipoyl(octanoyl) transferase activity
TthSNM17_01420	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
TthSNM17_01530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TthSNM17_01560	COG1598	PFAM Uncharacterised protein family UPF0150
TthSNM17_01570	COG0022	dehydrogenase e1 component
TthSNM17_01580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
TthSNM17_01590	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
TthSNM17_01640	COG2226	methyltransferase
TthSNM17_01650	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TthSNM17_01670	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
TthSNM17_01680	COG1187	pseudouridine synthase activity
TthSNM17_01700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TthSNM17_01710	COG0686	Belongs to the AlaDH PNT family
TthSNM17_01730	COG1461	Dihydroxyacetone kinase
TthSNM17_01750	COG3583	domain protein
TthSNM17_01750	COG3584	3D domain protein
TthSNM17_01760	COG4591	ABC-type transport system involved in lipoprotein release permease component
TthSNM17_01770	COG0222	ribosome binding
TthSNM17_01780	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
TthSNM17_01810	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
TthSNM17_01840	COG0697	spore germination
TthSNM17_01860	COG3177	Filamentation induced by cAMP protein fic
TthSNM17_01880	COG0243	molybdopterin cofactor binding
TthSNM17_01890	COG2272	Belongs to the type-B carboxylesterase lipase family
TthSNM17_01900	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TthSNM17_01920	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
TthSNM17_01950	COG0477	Major facilitator Superfamily
TthSNM17_01980	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
TthSNM17_02000	COG0105	UTP biosynthetic process
TthSNM17_02010	COG0631	protein serine/threonine phosphatase activity
TthSNM17_02020	COG0583	DNA-binding transcription factor activity
TthSNM17_02040	COG0508	dehydrogenase complex catalyzes the overall conversion of
TthSNM17_02110	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
TthSNM17_02130	COG1278	Cold shock
TthSNM17_02140	COG0484	heat shock protein binding
TthSNM17_02150	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TthSNM17_02160	COG1968	undecaprenyl-diphosphatase activity
TthSNM17_02170	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
TthSNM17_02180	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TthSNM17_02220	COG1309	transcriptional regulator
TthSNM17_02230	COG4242	Belongs to the peptidase S51 family
TthSNM17_02260	COG0802	atpase or kinase
TthSNM17_02270	COG0539	negative regulation of cytoplasmic translation
TthSNM17_02280	COG0495	leucyl-tRNA aminoacylation
TthSNM17_02320	COG1902	pentaerythritol trinitrate reductase activity
TthSNM17_02370	COG2414	aldehyde ferredoxin oxidoreductase
TthSNM17_02410	COG1187	pseudouridine synthase activity
TthSNM17_02430	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TthSNM17_02440	COG0745	RESPONSE REGULATOR receiver
TthSNM17_02450	COG4191	Histidine kinase
TthSNM17_02460	COG0704	Plays a role in the regulation of phosphate uptake
TthSNM17_02470	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TthSNM17_02490	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TthSNM17_02510	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TthSNM17_02510	COG0515	serine threonine protein kinase
TthSNM17_02550	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TthSNM17_02560	COG0300	oxidoreductase activity
TthSNM17_02590	COG0717	Belongs to the dCTP deaminase family
TthSNM17_02600	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
TthSNM17_02610	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TthSNM17_02620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TthSNM17_02670	COG3546	catalase activity
TthSNM17_02680	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TthSNM17_02680	COG0758	DNA mediated transformation
TthSNM17_02690	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TthSNM17_02710	COG0582	viral genome integration into host DNA
TthSNM17_02760	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TthSNM17_02810	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TthSNM17_02830	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
TthSNM17_02840	COG0442	prolyl-tRNA aminoacylation
TthSNM17_02850	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TthSNM17_02900	COG0513	Belongs to the DEAD box helicase family
TthSNM17_02950	COG4983	Phage plasmid primase, P4 family domain protein
TthSNM17_03030	COG0582	viral genome integration into host DNA
TthSNM17_03060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TthSNM17_03090	COG2070	2-Nitropropane dioxygenase
TthSNM17_03120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TthSNM17_03130	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TthSNM17_03140	COG0018	arginyl-trna synthetase
TthSNM17_03150	COG1007	ATP synthesis coupled electron transport
TthSNM17_03160	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TthSNM17_03170	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
TthSNM17_03180	COG0713	ATP synthesis coupled electron transport
TthSNM17_03190	COG0839	Belongs to the complex I subunit 6 family
TthSNM17_03200	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TthSNM17_03210	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
TthSNM17_03220	COG1034	ATP synthesis coupled electron transport
TthSNM17_03230	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TthSNM17_03240	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
TthSNM17_03250	COG0649	NAD binding
TthSNM17_03260	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TthSNM17_03270	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TthSNM17_03280	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TthSNM17_03290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TthSNM17_03310	COG4712	double-strand break repair protein
TthSNM17_03340	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TthSNM17_03370	COG0135	phosphoribosylanthranilate isomerase activity
TthSNM17_03380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TthSNM17_03380	COG1372	Participates in initiation and elongation during chromosome replication
TthSNM17_03390	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TthSNM17_03410	COG2720	vancomycin resistance protein
TthSNM17_03420	COG1126	abc transporter atp-binding protein
TthSNM17_03480	COG0277	FAD linked oxidase domain protein
TthSNM17_03500	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TthSNM17_03510	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TthSNM17_03540	COG0314	molybdopterin synthase activity
TthSNM17_03550	COG1420	regulation of RNA biosynthetic process
TthSNM17_03560	COG0347	Belongs to the P(II) protein family
TthSNM17_03590	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
TthSNM17_03610	COG0123	including yeast histone deacetylase and acetoin utilization protein
TthSNM17_03640	COG1597	lipid kinase activity
TthSNM17_03650	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
TthSNM17_03670	COG0436	Aminotransferase
TthSNM17_03690	COG0569	domain protein
TthSNM17_03690	COG0475	glutathione-regulated potassium exporter activity
TthSNM17_03720	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TthSNM17_03740	COG0277	FAD linked oxidase domain protein
TthSNM17_03860	COG2002	toxin-antitoxin pair type II binding
TthSNM17_03990	COG0667	Aldo Keto reductase
TthSNM17_04030	COG1067	ATP-dependent peptidase activity
TthSNM17_04040	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
TthSNM17_04060	COG0745	RESPONSE REGULATOR receiver
TthSNM17_04070	COG2105	PFAM AIG2 family protein
TthSNM17_04080	COG0297	glycogen (starch) synthase activity
TthSNM17_04100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TthSNM17_04110	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TthSNM17_04140	COG0142	geranyltranstransferase activity
TthSNM17_04160	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
TthSNM17_04170	COG1028	Short-chain dehydrogenase reductase Sdr
TthSNM17_04180	COG0492	ferredoxin-NADP+ reductase activity
TthSNM17_04200	COG0792	nuclease activity
TthSNM17_04210	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TthSNM17_04240	COG1175	transmembrane transport
TthSNM17_04250	COG0395	ABC-type sugar transport system, permease component
TthSNM17_04310	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
TthSNM17_04320	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TthSNM17_04330	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TthSNM17_04340	COG0805	protein transport
TthSNM17_04350	COG1605	Chorismate mutase
TthSNM17_04350	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TthSNM17_04360	COG1605	Chorismate mutase
TthSNM17_04360	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TthSNM17_04380	COG3573	Dehydrogenase
TthSNM17_04480	COG1063	alcohol dehydrogenase
TthSNM17_04540	COG2255	four-way junction helicase activity
TthSNM17_04550	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
TthSNM17_04560	COG0564	pseudouridine synthase activity
TthSNM17_04610	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TthSNM17_04620	COG0232	Belongs to the dGTPase family. Type 2 subfamily
TthSNM17_04630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TthSNM17_04640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TthSNM17_04660	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
TthSNM17_04670	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TthSNM17_04680	COG0333	Belongs to the bacterial ribosomal protein bL32 family
TthSNM17_04750	COG0778	Nitroreductase
TthSNM17_04770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TthSNM17_04780	COG0131	Imidazoleglycerol-phosphate dehydratase
TthSNM17_04790	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
TthSNM17_04800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TthSNM17_04810	COG0517	IMP dehydrogenase activity
TthSNM17_04810	COG0516	GMP reductase activity
TthSNM17_04840	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
TthSNM17_04870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TthSNM17_04920	COG0706	membrane insertase activity
TthSNM17_04930	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
TthSNM17_04940	COG0594	ribonuclease P activity
TthSNM17_04970	COG1022	Amp-dependent synthetase and ligase
TthSNM17_05020	COG1121	(ABC) transporter
TthSNM17_05030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TthSNM17_05040	COG1959	2 iron, 2 sulfur cluster binding
TthSNM17_05050	COG1104	cysteine desulfurase activity
TthSNM17_05060	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
TthSNM17_05070	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TthSNM17_05100	COG1028	Short-chain dehydrogenase reductase Sdr
TthSNM17_05140	COG0492	ferredoxin-NADP+ reductase activity
TthSNM17_05150	COG1028	Short-chain dehydrogenase reductase Sdr
TthSNM17_05150	COG0604	alcohol dehydrogenase
TthSNM17_05150	COG3321	synthase
TthSNM17_05160	COG0747	negative chemotaxis
TthSNM17_05170	COG0601	transmembrane transport
TthSNM17_05180	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TthSNM17_05210	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TthSNM17_05210	COG0617	tRNA 3'-terminal CCA addition
TthSNM17_05210	COG0517	IMP dehydrogenase activity
TthSNM17_05220	COG0123	including yeast histone deacetylase and acetoin utilization protein
TthSNM17_05230	COG2104	thiamine diphosphate biosynthetic process
TthSNM17_05240	COG0037	tRNA processing
TthSNM17_05260	COG0366	Alpha amylase catalytic
TthSNM17_05270	COG2226	methyltransferase
TthSNM17_05280	COG2226	methyltransferase
TthSNM17_05290	COG0815	Transfers the fatty acyl group on membrane lipoproteins
TthSNM17_05310	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
TthSNM17_05320	COG3744	PilT protein domain protein
TthSNM17_05340	COG0460	homoserine dehydrogenase
TthSNM17_05360	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TthSNM17_05420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TthSNM17_05470	COG0247	lactate metabolic process
TthSNM17_05480	COG0277	FAD linked oxidase domain protein
TthSNM17_05490	COG0277	FAD linked oxidase domain protein
TthSNM17_05500	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
TthSNM17_05510	COG1414	Transcriptional regulator
TthSNM17_05520	COG0789	Transcriptional regulator
TthSNM17_05540	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TthSNM17_05550	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
TthSNM17_05620	COG0861	Integral membrane protein TerC family
TthSNM17_05630	COG2151	metal-sulfur cluster biosynthetic enzyme
TthSNM17_05640	COG0281	malic enzyme
TthSNM17_05670	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TthSNM17_05680	COG0509	glycine decarboxylation via glycine cleavage system
TthSNM17_05690	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TthSNM17_05700	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TthSNM17_05710	COG0196	riboflavin kinase activity
TthSNM17_05760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TthSNM17_05770	COG2813	Specifically methylates the guanine in position
TthSNM17_05780	COG0527	aspartate kinase activity
TthSNM17_05840	COG4956	integral membrane protein (PIN domain superfamily)
TthSNM17_05850	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TthSNM17_05860	COG0542	response to heat
TthSNM17_05870	COG0423	glycine-tRNA ligase activity
TthSNM17_05900	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
TthSNM17_05940	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TthSNM17_05940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TthSNM17_05960	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
TthSNM17_05980	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TthSNM17_06000	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TthSNM17_06010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TthSNM17_06020	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
TthSNM17_06030	COG0114	fumarate hydratase activity
TthSNM17_06040	COG0183	Belongs to the thiolase family
TthSNM17_06070	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TthSNM17_06080	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
TthSNM17_06110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TthSNM17_06120	COG1254	Belongs to the acylphosphatase family
TthSNM17_06150	COG1063	alcohol dehydrogenase
TthSNM17_06160	COG2133	pyrroloquinoline quinone binding
TthSNM17_06180	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TthSNM17_06190	COG0154	amidase activity
TthSNM17_06200	COG2176	DNA-directed DNA polymerase activity
TthSNM17_06240	COG0572	uridine kinase
TthSNM17_06250	COG3842	ATPase activity
TthSNM17_06280	COG4475	Protein of unknown function (DUF436)
TthSNM17_06310	COG1022	Amp-dependent synthetase and ligase
TthSNM17_06330	COG0318	PFAM AMP-dependent synthetase and ligase
TthSNM17_06360	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
TthSNM17_06450	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
TthSNM17_06460	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TthSNM17_06470	COG0803	Belongs to the bacterial solute-binding protein 9 family
TthSNM17_06500	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
TthSNM17_06510	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
TthSNM17_06520	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
TthSNM17_06530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TthSNM17_06550	COG0318	PFAM AMP-dependent synthetase and ligase
TthSNM17_06580	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
TthSNM17_06590	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TthSNM17_06600	COG1293	RNA-binding protein homologous to eukaryotic snRNP
TthSNM17_06610	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
TthSNM17_06630	COG3870	Protein conserved in bacteria
TthSNM17_06640	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TthSNM17_06660	COG0544	peptidyl-prolyl cis-trans isomerase activity
TthSNM17_06670	COG0740	serine-type endopeptidase activity
TthSNM17_06680	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
TthSNM17_06690	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
TthSNM17_06700	COG1410	methionine synthase
TthSNM17_06700	COG0646	methionine synthase
TthSNM17_06720	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TthSNM17_06770	COG1692	metallophosphoesterase
TthSNM17_06780	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
TthSNM17_06790	COG1970	mechanosensitive ion channel activity
TthSNM17_06880	COG2189	Belongs to the N(4) N(6)-methyltransferase family
TthSNM17_06900	COG0582	viral genome integration into host DNA
TthSNM17_06910	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TthSNM17_06930	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
TthSNM17_06940	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
TthSNM17_07050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
TthSNM17_07080	COG1215	transferase activity, transferring glycosyl groups
TthSNM17_07100	COG1215	transferase activity, transferring glycosyl groups
TthSNM17_07130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TthSNM17_07170	COG0489	protein tyrosine kinase activity
TthSNM17_07190	COG2264	protein methyltransferase activity
TthSNM17_07200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
TthSNM17_07270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TthSNM17_07280	COG2046	Belongs to the sulfate adenylyltransferase family
TthSNM17_07290	COG1648	precorrin-2 dehydrogenase activity
TthSNM17_07290	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TthSNM17_07300	COG0730	response to heat
TthSNM17_07310	COG0175	sulfate reduction
TthSNM17_07320	COG1648	precorrin-2 dehydrogenase activity
TthSNM17_07320	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TthSNM17_07330	COG1587	Uroporphyrinogen-III synthase
TthSNM17_07340	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TthSNM17_07360	COG0352	thiamine-phosphate diphosphorylase activity
TthSNM17_07370	COG2104	thiamine diphosphate biosynthetic process
TthSNM17_07380	COG2022	thiamine diphosphate biosynthetic process
TthSNM17_07390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TthSNM17_07390	COG2022	thiamine diphosphate biosynthetic process
TthSNM17_07400	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
TthSNM17_07410	COG0477	Major facilitator Superfamily
TthSNM17_07420	COG0352	thiamine-phosphate diphosphorylase activity
TthSNM17_07420	COG0351	phosphomethylpyrimidine kinase
TthSNM17_07480	COG1175	transmembrane transport
TthSNM17_07510	COG1940	carbohydrate kinase activity
TthSNM17_07520	COG0183	Belongs to the thiolase family
TthSNM17_07550	COG1028	Short-chain dehydrogenase reductase Sdr
TthSNM17_07610	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TthSNM17_07610	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TthSNM17_07630	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TthSNM17_07650	COG0195	Participates in both transcription termination and antitermination
TthSNM17_07660	COG0779	Required for maturation of 30S ribosomal subunits
TthSNM17_07670	COG0739	heme binding
TthSNM17_07680	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
TthSNM17_07690	COG0640	Transcriptional regulator
TthSNM17_07700	COG2217	Heavy metal translocating P-type atpase
TthSNM17_07710	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
TthSNM17_07720	COG0017	Asparaginyl-tRNA synthetase
TthSNM17_07730	COG0561	phosphatase activity
TthSNM17_07740	COG0384	phenazine biosynthesis protein PhzF
TthSNM17_07760	COG0124	histidyl-tRNA synthetase
TthSNM17_07780	COG3842	ATPase activity
TthSNM17_07820	COG1573	uracil-dna glycosylase
TthSNM17_07860	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TthSNM17_07890	COG1316	TRANSCRIPTIONal
TthSNM17_07900	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TthSNM17_07990	COG0295	cytidine deaminase activity
TthSNM17_08010	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TthSNM17_08030	COG1760	l-serine dehydratase
TthSNM17_08050	COG0481	GTPase activity
TthSNM17_08070	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TthSNM17_08100	COG1028	Short-chain dehydrogenase reductase Sdr
TthSNM17_08150	COG0405	Gamma-glutamyltransferase
TthSNM17_08160	COG1073	alpha beta
TthSNM17_08190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
TthSNM17_08200	COG2873	o-acetylhomoserine
TthSNM17_08230	COG1063	alcohol dehydrogenase
TthSNM17_08250	COG3191	aminopeptidase activity
TthSNM17_08260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TthSNM17_08270	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TthSNM17_08280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TthSNM17_08290	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
TthSNM17_08300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TthSNM17_08320	COG0167	dihydroorotate dehydrogenase activity
TthSNM17_08350	COG0540	Belongs to the ATCase OTCase family
TthSNM17_08360	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
TthSNM17_08380	COG0730	response to heat
TthSNM17_08390	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TthSNM17_08410	COG1960	acyl-CoA dehydrogenase activity
TthSNM17_08420	COG0456	acetyltransferase
TthSNM17_08440	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
TthSNM17_08450	COG0009	L-threonylcarbamoyladenylate synthase
TthSNM17_08460	COG1459	type II secretion system
TthSNM17_08490	COG0277	FAD linked oxidase domain protein
TthSNM17_08520	COG0287	Prephenate dehydrogenase
TthSNM17_08530	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TthSNM17_08540	COG2514	catechol 2,3-dioxygenase activity
TthSNM17_08550	COG2353	YceI-like domain
TthSNM17_08560	COG1427	Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
TthSNM17_08570	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TthSNM17_08610	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TthSNM17_08620	COG0179	Fumarylacetoacetate (FAA) hydrolase
TthSNM17_08640	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
TthSNM17_08650	COG0151	Belongs to the GarS family
TthSNM17_08660	COG2176	DNA-directed DNA polymerase activity
TthSNM17_08660	COG5002	protein histidine kinase activity
TthSNM17_08720	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TthSNM17_08740	COG0217	transcriptional regulatory protein
TthSNM17_08750	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TthSNM17_08750	COG4651	solute:proton antiporter activity
TthSNM17_08760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
TthSNM17_08770	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
TthSNM17_08780	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TthSNM17_08790	COG1674	ftsk spoiiie
TthSNM17_08820	COG0517	IMP dehydrogenase activity
TthSNM17_08840	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TthSNM17_08840	COG3620	sequence-specific DNA binding
TthSNM17_08840	COG0617	tRNA 3'-terminal CCA addition
TthSNM17_08860	COG1994	Peptidase M50
TthSNM17_08870	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
TthSNM17_08890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TthSNM17_08920	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
TthSNM17_08940	COG2719	SpoVR family
TthSNM17_08950	COG2718	Belongs to the UPF0229 family
TthSNM17_08960	COG2766	serine protein kinase
TthSNM17_09010	COG2137	regulation of response to DNA damage stimulus
TthSNM17_09030	COG2359	stage V sporulation protein S
TthSNM17_09040	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TthSNM17_09050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TthSNM17_09070	COG0463	Glycosyl transferase, family 2
TthSNM17_09080	COG0750	zinc metalloprotease
TthSNM17_09090	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TthSNM17_09100	COG4589	Belongs to the CDS family
TthSNM17_09110	COG0233	cytoplasmic translational termination
TthSNM17_09120	COG0528	UMP kinase activity
TthSNM17_09130	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TthSNM17_09140	COG0052	Belongs to the universal ribosomal protein uS2 family
TthSNM17_09150	COG0582	viral genome integration into host DNA
TthSNM17_09310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
TthSNM17_09320	COG0494	nUDIX hydrolase
TthSNM17_09380	COG0402	S-adenosylhomocysteine deaminase activity
TthSNM17_09400	COG4948	Mandelate Racemase Muconate Lactonizing
TthSNM17_09410	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TthSNM17_09420	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TthSNM17_09430	COG1811	Na channel or pump
TthSNM17_09440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TthSNM17_09440	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
TthSNM17_09470	COG1215	transferase activity, transferring glycosyl groups
TthSNM17_09490	COG1215	transferase activity, transferring glycosyl groups
TthSNM17_09510	COG0438	transferase activity, transferring glycosyl groups
TthSNM17_09520	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
TthSNM17_09570	COG1024	Enoyl-CoA hydratase
TthSNM17_09570	COG1250	3-hydroxyacyl-CoA dehydrogenase
TthSNM17_09580	COG0183	Belongs to the thiolase family
TthSNM17_09590	COG1960	acyl-CoA dehydrogenase activity
TthSNM17_09600	COG0215	cysteine-tRNA ligase activity
TthSNM17_09610	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
TthSNM17_09630	COG2738	Putative neutral zinc metallopeptidase
TthSNM17_09660	COG1196	nuclear chromosome segregation
TthSNM17_09690	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TthSNM17_09700	COG3153	acetyltransferase
TthSNM17_09700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TthSNM17_09710	COG1268	BioY protein
TthSNM17_09730	COG0126	phosphoglycerate kinase activity
TthSNM17_09740	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TthSNM17_09750	COG0824	Thioesterase
TthSNM17_09770	COG0557	exoribonuclease II activity
TthSNM17_09780	COG1355	regulation of microtubule-based process
TthSNM17_09790	COG0617	tRNA 3'-terminal CCA addition
TthSNM17_09790	COG1353	crispr-associated protein
TthSNM17_09800	COG0237	dephospho-CoA kinase activity
TthSNM17_09820	COG0742	ribosomal rna small subunit methyltransferase
TthSNM17_09830	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TthSNM17_09840	COG0138	bifunctional purine biosynthesis protein purh
TthSNM17_09850	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
TthSNM17_09880	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TthSNM17_09950	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TthSNM17_10000	COG0149	triose-phosphate isomerase activity
TthSNM17_10010	COG3239	Fatty acid desaturase
TthSNM17_10030	COG1490	D-aminoacyl-tRNA deacylase activity
TthSNM17_10040	COG1307	EDD domain protein, DegV family
TthSNM17_10050	COG1307	EDD domain protein, DegV family
TthSNM17_10060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TthSNM17_10090	COG3769	mannosylglycerate metabolic process
TthSNM17_10130	COG2368	4-hydroxyphenylacetate
TthSNM17_10140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TthSNM17_10190	COG0410	ABC transporter
TthSNM17_10200	COG2050	protein possibly involved in aromatic compounds catabolism
TthSNM17_10210	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
TthSNM17_10230	COG1012	belongs to the aldehyde dehydrogenase family
TthSNM17_10230	COG2030	dehydratase
TthSNM17_10270	COG3396	Phenylacetate-CoA oxygenase
TthSNM17_10290	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
TthSNM17_10320	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
TthSNM17_10330	COG1607	acyl-coa hydrolase
TthSNM17_10350	COG1980	fructose-bisphosphate aldolase activity
TthSNM17_10360	COG1733	regulation of RNA biosynthetic process
TthSNM17_10370	COG2193	ferroxidase activity
TthSNM17_10380	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
TthSNM17_10390	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
TthSNM17_10430	COG1331	Highly conserved protein containing a thioredoxin domain
TthSNM17_10440	COG0183	Belongs to the thiolase family
TthSNM17_10450	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
TthSNM17_10510	COG0745	RESPONSE REGULATOR receiver
TthSNM17_10520	COG1012	belongs to the aldehyde dehydrogenase family
TthSNM17_10540	COG0248	Ppx GppA phosphatase
TthSNM17_10550	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
TthSNM17_10560	COG0210	DNA helicase
TthSNM17_10620	COG0745	RESPONSE REGULATOR receiver
TthSNM17_10630	COG2205	protein histidine kinase activity
TthSNM17_10670	COG1136	(ABC) transporter
TthSNM17_10690	COG0577	efflux transmembrane transporter activity
TthSNM17_10690	COG1136	(ABC) transporter
TthSNM17_10740	COG2897	thiosulfate sulfurtransferase activity
TthSNM17_10750	COG1760	l-serine dehydratase
TthSNM17_10760	COG2197	response regulator
TthSNM17_10770	COG0335	large ribosomal subunit rRNA binding
TthSNM17_10780	COG0336	Belongs to the RNA methyltransferase TrmD family
TthSNM17_10790	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
TthSNM17_10800	COG1837	Belongs to the UPF0109 family
TthSNM17_10810	COG0228	four-way junction DNA binding
TthSNM17_10840	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TthSNM17_10850	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TthSNM17_10850	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TthSNM17_10860	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TthSNM17_10880	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TthSNM17_10900	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
TthSNM17_10910	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
TthSNM17_10920	COG1702	phosphate starvation-inducible protein PhoH
TthSNM17_10940	COG4864	UPF0365 protein
TthSNM17_10960	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TthSNM17_11000	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TthSNM17_11000	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TthSNM17_11010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TthSNM17_11030	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
TthSNM17_11040	COG1397	ADP-ribosylglycohydrolase
TthSNM17_11050	COG2239	Acts as a magnesium transporter
TthSNM17_11060	COG2304	oxidoreductase activity
TthSNM17_11070	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TthSNM17_11070	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
TthSNM17_11090	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TthSNM17_11090	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TthSNM17_11100	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
TthSNM17_11110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
TthSNM17_11120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TthSNM17_11130	COG0006	proline dipeptidase activity
TthSNM17_11150	COG0739	heme binding
TthSNM17_11170	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
TthSNM17_11180	COG0254	rRNA binding
TthSNM17_11200	COG2001	Belongs to the MraZ family
TthSNM17_11210	COG0275	rRNA processing
TthSNM17_11230	COG0768	penicillin binding
TthSNM17_11240	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TthSNM17_11260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TthSNM17_11270	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TthSNM17_11280	COG0772	Belongs to the SEDS family
TthSNM17_11290	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TthSNM17_11300	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TthSNM17_11310	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TthSNM17_11350	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
TthSNM17_11370	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
TthSNM17_11390	COG0159	tryptophan synthase activity
TthSNM17_11400	COG0133	tryptophan synthase activity
TthSNM17_11410	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TthSNM17_11420	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TthSNM17_11430	COG1744	ABC transporter substrate-binding protein PnrA-like
TthSNM17_11440	COG3845	ABC transporter
TthSNM17_11540	COG0438	transferase activity, transferring glycosyl groups
TthSNM17_11550	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TthSNM17_11570	COG0039	L-malate dehydrogenase activity
TthSNM17_11580	COG2819	hydrolase of the alpha beta superfamily
TthSNM17_11610	COG0247	lactate metabolic process
TthSNM17_11610	COG2181	nitrate reductase activity
TthSNM17_11630	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
TthSNM17_11640	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TthSNM17_11650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TthSNM17_11670	COG0439	Biotin carboxylase
TthSNM17_11680	COG0511	ligase activity, forming carbon-carbon bonds
TthSNM17_11690	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
TthSNM17_11730	COG0010	Belongs to the arginase family
TthSNM17_11760	COG1100	Small GTP-binding protein
TthSNM17_11780	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
TthSNM17_11790	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
TthSNM17_11810	COG2814	Major facilitator Superfamily
TthSNM17_11820	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TthSNM17_11830	COG1185	polyribonucleotide nucleotidyltransferase activity
TthSNM17_11840	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
TthSNM17_11850	COG0589	response to stress
TthSNM17_11870	COG2239	Acts as a magnesium transporter
TthSNM17_11880	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
TthSNM17_11890	COG0745	RESPONSE REGULATOR receiver
TthSNM17_11900	COG5002	protein histidine kinase activity
TthSNM17_11910	COG1960	acyl-CoA dehydrogenase activity
TthSNM17_11920	COG2086	electron transfer activity
TthSNM17_11930	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
TthSNM17_11950	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TthSNM17_11960	COG1573	uracil-dna glycosylase
TthSNM17_11970	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TthSNM17_11970	COG1796	DNA polymerase
TthSNM17_12000	COG2309	aminopeptidase activity
TthSNM17_12040	COG2873	o-acetylhomoserine
TthSNM17_12050	COG2358	TRAP transporter, solute receptor (TAXI family
TthSNM17_12070	COG1126	abc transporter atp-binding protein
TthSNM17_12090	COG1752	Esterase of the alpha-beta hydrolase superfamily
TthSNM17_12100	COG3311	Transcriptional regulator
TthSNM17_12120	COG0134	indole-3-glycerol-phosphate synthase activity
TthSNM17_12130	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
TthSNM17_12150	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
TthSNM17_12180	COG0765	amino acid transport
TthSNM17_12190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TthSNM17_12210	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TthSNM17_12220	COG0569	domain protein
TthSNM17_12230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TthSNM17_12240	COG1426	Protein conserved in bacteria
TthSNM17_12250	COG2313	pseudouridylate synthase activity
TthSNM17_12270	COG3001	Fructosamine kinase
TthSNM17_12280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TthSNM17_12300	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
TthSNM17_12330	COG0012	GTP binding
TthSNM17_12340	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TthSNM17_12360	COG0424	maF-like protein
TthSNM17_12390	COG0768	penicillin binding
TthSNM17_12400	COG0850	regulation of cytokinetic process
TthSNM17_12450	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
TthSNM17_12460	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TthSNM17_12480	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TthSNM17_12520	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TthSNM17_12580	COG1131	(ABC) transporter
TthSNM17_12610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TthSNM17_12630	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TthSNM17_12640	COG0440	acetolactate synthase activity
TthSNM17_12650	COG0028	Belongs to the TPP enzyme family
TthSNM17_12660	COG0492	ferredoxin-NADP+ reductase activity
TthSNM17_12670	COG4970	Tfp pilus assembly protein FimT
TthSNM17_12680	COG2165	general secretion pathway protein
TthSNM17_12690	COG4966	pilus assembly protein PilW
TthSNM17_12710	COG2165	general secretion pathway protein
TthSNM17_12790	COG0180	Tryptophanyl-tRNA synthetase
TthSNM17_12800	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TthSNM17_12810	COG0066	3-isopropylmalate dehydratase activity
TthSNM17_12820	COG0473	3-isopropylmalate dehydrogenase activity
TthSNM17_12850	COG0300	oxidoreductase activity
TthSNM17_12860	COG0129	dihydroxy-acid dehydratase activity
TthSNM17_12880	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
TthSNM17_12890	COG1177	transmembrane transport
TthSNM17_12900	COG1176	ABC-type spermidine putrescine transport system, permease component I
TthSNM17_12910	COG3842	ATPase activity
TthSNM17_12920	COG0772	Belongs to the SEDS family
TthSNM17_12930	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
TthSNM17_12940	COG2894	cell division
TthSNM17_12950	COG1733	regulation of RNA biosynthetic process
TthSNM17_12970	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TthSNM17_12970	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
TthSNM17_12990	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TthSNM17_13000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TthSNM17_13010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TthSNM17_13020	COG0653	protein targeting
TthSNM17_13030	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TthSNM17_13070	COG0393	Putative heavy-metal-binding
TthSNM17_13080	COG1111	helicase
TthSNM17_13080	COG1205	dead DEAH box helicase
TthSNM17_13110	COG0358	DNA primase activity
TthSNM17_13130	COG1250	3-hydroxyacyl-CoA dehydrogenase
TthSNM17_13140	COG0612	Peptidase, M16
TthSNM17_13150	COG0612	Peptidase, M16
TthSNM17_13160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TthSNM17_13190	COG1394	ATPase activity, coupled to movement of substances
TthSNM17_13200	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TthSNM17_13210	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TthSNM17_13220	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
TthSNM17_13230	COG1527	subunit (C
TthSNM17_13240	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
TthSNM17_13260	COG1269	ATP hydrolysis coupled proton transport
TthSNM17_13310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TthSNM17_13330	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TthSNM17_13360	COG0419	ATPase involved in DNA repair
TthSNM17_13370	COG0420	3'-5' exonuclease activity
TthSNM17_13410	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
TthSNM17_13420	COG2884	Cell division ATP-binding protein ftsE
TthSNM17_13430	COG0793	Belongs to the peptidase S41A family
TthSNM17_13440	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TthSNM17_13440	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TthSNM17_13450	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
TthSNM17_13460	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TthSNM17_13480	COG1079	Belongs to the binding-protein-dependent transport system permease family
TthSNM17_13490	COG4603	Belongs to the binding-protein-dependent transport system permease family
TthSNM17_13500	COG1129	ABC transporter
TthSNM17_13510	COG0746	molybdenum cofactor guanylyltransferase activity
TthSNM17_13530	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TthSNM17_13570	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TthSNM17_13580	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TthSNM17_13590	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
TthSNM17_13610	COG0517	IMP dehydrogenase activity
TthSNM17_13610	COG1994	Peptidase M50
TthSNM17_13620	COG2358	TRAP transporter, solute receptor (TAXI family
TthSNM17_13640	COG2358	TRAP transporter, solute receptor (TAXI family
TthSNM17_13670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TthSNM17_13680	COG0788	formyltetrahydrofolate deformylase activity
TthSNM17_13690	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
TthSNM17_13700	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
TthSNM17_13710	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TthSNM17_13730	COG2010	Cytochrome c
TthSNM17_13750	COG0737	Belongs to the 5'-nucleotidase family
TthSNM17_13760	COG0174	glutamine synthetase
TthSNM17_13800	COG0559	Belongs to the binding-protein-dependent transport system permease family
TthSNM17_13840	COG0747	negative chemotaxis
TthSNM17_13850	COG0601	transmembrane transport
TthSNM17_13860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TthSNM17_13880	COG0285	dihydrofolate synthase activity
TthSNM17_13890	COG1132	(ABC) transporter
TthSNM17_13900	COG1132	(ABC) transporter
TthSNM17_13910	COG0372	Belongs to the citrate synthase family
TthSNM17_13920	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TthSNM17_13930	COG1482	cell wall glycoprotein biosynthetic process
TthSNM17_13950	COG1515	deoxyribonuclease V activity
TthSNM17_13970	COG0776	regulation of translation
TthSNM17_14000	COG2197	response regulator
TthSNM17_14010	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TthSNM17_14020	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
TthSNM17_14030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TthSNM17_14040	COG1324	tolerance protein
TthSNM17_14070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TthSNM17_14110	COG2205	protein histidine kinase activity
TthSNM17_14130	COG0247	lactate metabolic process
TthSNM17_14140	COG1139	Iron-sulfur cluster binding protein
TthSNM17_14150	COG1556	Lactate utilization protein
TthSNM17_14170	COG1752	Esterase of the alpha-beta hydrolase superfamily
TthSNM17_14180	COG2815	serine threonine protein kinase
TthSNM17_14180	COG0515	serine threonine protein kinase
TthSNM17_14200	COG0860	N-Acetylmuramoyl-L-alanine amidase
TthSNM17_14220	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
TthSNM17_14250	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
TthSNM17_14250	COG2199	diguanylate cyclase activity
TthSNM17_14270	COG0473	3-isopropylmalate dehydrogenase activity
TthSNM17_14320	COG1450	Type ii and iii secretion system protein
TthSNM17_14330	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TthSNM17_14340	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TthSNM17_14350	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TthSNM17_14360	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
TthSNM17_14360	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TthSNM17_14370	COG0736	holo-[acyl-carrier-protein] synthase activity
TthSNM17_14400	COG1160	GTP binding
TthSNM17_14410	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TthSNM17_14420	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TthSNM17_14420	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TthSNM17_14460	COG0083	homoserine kinase activity
TthSNM17_14480	COG0268	Binds directly to 16S ribosomal RNA
TthSNM17_14500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TthSNM17_14530	COG3088	subunit of a heme lyase
TthSNM17_14530	COG4235	cytochrome complex assembly
TthSNM17_14540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TthSNM17_14550	COG1138	Cytochrome C-type biogenesis protein
TthSNM17_14560	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
TthSNM17_14570	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TthSNM17_14580	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TthSNM17_14590	COG4133	protoheme IX ABC transporter activity
TthSNM17_14600	COG0785	Cytochrome C biogenesis protein
TthSNM17_14630	COG3258	Cytochrome c
TthSNM17_14650	COG0446	pyridine nucleotide-disulphide oxidoreductase
TthSNM17_14680	COG3258	Cytochrome c
TthSNM17_14690	COG2010	Cytochrome c
TthSNM17_14700	COG0737	Belongs to the 5'-nucleotidase family
TthSNM17_14710	COG2010	Cytochrome c
TthSNM17_14720	COG3258	Cytochrome c
TthSNM17_14760	COG2010	Cytochrome c
TthSNM17_14770	COG3842	ATPase activity
TthSNM17_14830	COG0318	PFAM AMP-dependent synthetase and ligase
TthSNM17_14840	COG3360	Dodecin
TthSNM17_14870	COG1024	Enoyl-CoA hydratase
TthSNM17_14880	COG0813	purine-nucleoside phosphorylase activity
TthSNM17_14890	COG1136	(ABC) transporter
TthSNM17_14900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TthSNM17_14910	COG2045	Belongs to the ComB family
TthSNM17_14930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TthSNM17_14950	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
TthSNM17_14970	COG0107	imidazoleglycerol-phosphate synthase activity
TthSNM17_14980	COG0140	phosphoribosyl-ATP diphosphatase activity
TthSNM17_14980	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TthSNM17_14990	COG1494	fructose-1,6-bisphosphatase
TthSNM17_15000	COG0686	Belongs to the AlaDH PNT family
TthSNM17_15010	COG0427	acetyl-CoA hydrolase
TthSNM17_15020	COG0084	hydrolase, TatD family'
TthSNM17_15030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TthSNM17_15050	COG0017	Asparaginyl-tRNA synthetase
TthSNM17_15060	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
TthSNM17_15090	COG2009	succinate dehydrogenase
TthSNM17_15100	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
TthSNM17_15160	COG0318	PFAM AMP-dependent synthetase and ligase
TthSNM17_15170	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TthSNM17_15180	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TthSNM17_15190	COG0504	CTP synthase activity
TthSNM17_15210	COG0067	glutamate synthase
TthSNM17_15210	COG0069	glutamate synthase activity
TthSNM17_15210	COG0070	glutamate synthase
TthSNM17_15230	COG0840	transmembrane signaling receptor activity
TthSNM17_15240	COG0305	Participates in initiation and elongation during chromosome replication
TthSNM17_15260	COG0475	glutathione-regulated potassium exporter activity
TthSNM17_15270	COG0517	IMP dehydrogenase activity
TthSNM17_15270	COG0617	tRNA 3'-terminal CCA addition
TthSNM17_15270	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
TthSNM17_15300	COG0475	glutathione-regulated potassium exporter activity
TthSNM17_15310	COG0490	domain, Protein
TthSNM17_15350	COG3118	belongs to the thioredoxin family
TthSNM17_15410	COG0542	response to heat
TthSNM17_15420	COG0789	Transcriptional regulator
TthSNM17_15430	COG0484	heat shock protein binding
TthSNM17_15440	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TthSNM17_15450	COG0443	Heat shock 70 kDa protein
TthSNM17_15460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TthSNM17_15470	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
TthSNM17_15480	COG0616	signal peptide processing
TthSNM17_15510	COG1310	metal-dependent protease of the Pad1 Jab1 superfamily
TthSNM17_15520	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TthSNM17_15530	COG0714	Associated with various cellular activities
TthSNM17_15540	COG0574	Belongs to the PEP-utilizing enzyme family
TthSNM17_15540	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TthSNM17_15550	COG1272	protein, Hemolysin III
TthSNM17_15570	COG3850	Histidine kinase
TthSNM17_15570	COG5002	protein histidine kinase activity
TthSNM17_15590	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
TthSNM17_15620	COG1011	Hydrolase
TthSNM17_15670	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TthSNM17_15700	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
TthSNM17_15720	COG0047	phosphoribosylformylglycinamidine synthase activity
TthSNM17_15740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TthSNM17_15750	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
TthSNM17_15760	COG0116	Belongs to the methyltransferase superfamily
TthSNM17_15790	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TthSNM17_15800	COG0497	DNA recombination
TthSNM17_15820	COG0604	alcohol dehydrogenase
TthSNM17_15860	COG0585	pseudouridine synthase activity
TthSNM17_15890	COG0557	exoribonuclease II activity
TthSNM17_15900	COG0538	isocitrate dehydrogenase activity
TthSNM17_15910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TthSNM17_15940	COG0590	tRNA wobble adenosine to inosine editing
TthSNM17_15940	COG0037	tRNA processing
TthSNM17_15980	COG2050	protein possibly involved in aromatic compounds catabolism
TthSNM17_16000	COG0322	excinuclease ABC activity
TthSNM17_16010	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TthSNM17_16020	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TthSNM17_16030	COG1854	S-ribosylhomocysteine lyase activity
TthSNM17_16040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TthSNM17_16040	COG0519	Catalyzes the synthesis of GMP from XMP
TthSNM17_16060	COG4274	PFAM GYD family protein
TthSNM17_16080	COG0328	RNA-DNA hybrid ribonuclease activity
TthSNM17_16090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TthSNM17_16100	COG2095	MarC family integral membrane protein
TthSNM17_16110	COG1438	arginine binding
TthSNM17_16120	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
TthSNM17_16130	COG1758	RNA polymerase activity
TthSNM17_16140	COG0194	GDP metabolic process
TthSNM17_16160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TthSNM17_16170	COG2385	sporulation resulting in formation of a cellular spore
TthSNM17_16180	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
TthSNM17_16200	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
TthSNM17_16270	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TthSNM17_16280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TthSNM17_16290	COG1012	belongs to the aldehyde dehydrogenase family
TthSNM17_16300	COG0506	proline dehydrogenase activity
TthSNM17_16340	COG0156	8-amino-7-oxononanoate synthase activity
TthSNM17_16350	COG0732	type I restriction modification DNA specificity domain
TthSNM17_16350	COG0827	DNA restriction-modification system
TthSNM17_16370	COG0187	DNA topoisomerase II activity
TthSNM17_16380	COG1181	Belongs to the D-alanine--D-alanine ligase family
TthSNM17_16390	COG0193	aminoacyl-tRNA hydrolase activity
TthSNM17_16400	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
TthSNM17_16430	COG2815	serine threonine protein kinase
TthSNM17_16430	COG0515	serine threonine protein kinase
TthSNM17_16440	COG0631	protein serine/threonine phosphatase activity
TthSNM17_16470	COG0113	porphobilinogen synthase activity
TthSNM17_16480	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
TthSNM17_16490	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
TthSNM17_16540	COG1506	peptidase
TthSNM17_16540	COG0823	Involved in the tonB-independent uptake of proteins
TthSNM17_16540	COG4946	Tricorn protease homolog
TthSNM17_16560	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TthSNM17_16570	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TthSNM17_16610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
TthSNM17_16620	COG1011	Hydrolase
TthSNM17_16670	COG0537	adenosine 5'-monophosphoramidase activity
TthSNM17_16680	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TthSNM17_16690	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TthSNM17_16700	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
TthSNM17_16710	COG0071	Belongs to the small heat shock protein (HSP20) family
TthSNM17_16730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TthSNM17_16750	COG1764	response to oxidative stress
TthSNM17_16780	COG1840	ABC-type Fe3 transport system, periplasmic component
TthSNM17_16800	COG3842	ATPase activity
TthSNM17_16810	COG0101	tRNA pseudouridine synthase activity
TthSNM17_16820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TthSNM17_16830	COG0601	transmembrane transport
TthSNM17_16880	COG0006	proline dipeptidase activity
TthSNM17_16890	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TthSNM17_16920	COG1166	arginine decarboxylase activity
TthSNM17_16930	COG3706	GGDEF domain
TthSNM17_16940	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TthSNM17_16950	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
TthSNM17_16960	COG1611	Belongs to the LOG family
TthSNM17_16970	COG1193	negative regulation of DNA recombination
TthSNM17_16990	COG0366	Alpha amylase catalytic
TthSNM17_17060	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TthSNM17_17070	COG0142	geranyltranstransferase activity
TthSNM17_17090	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
TthSNM17_17150	COG0203	ribosomal protein L17
TthSNM17_17160	COG0202	RNA polymerase activity
TthSNM17_17170	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TthSNM17_17180	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TthSNM17_17190	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TthSNM17_17200	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TthSNM17_17220	COG0563	adenylate kinase activity
TthSNM17_17230	COG0201	protein transport
TthSNM17_17280	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TthSNM17_17290	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TthSNM17_17300	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TthSNM17_17350	COG0255	Belongs to the universal ribosomal protein uL29 family
TthSNM17_17360	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TthSNM17_17370	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TthSNM17_17390	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TthSNM17_17400	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TthSNM17_17410	COG0089	rRNA binding
TthSNM17_17420	COG0088	Forms part of the polypeptide exit tunnel
TthSNM17_17440	COG0051	transcription antitermination factor activity, RNA binding
TthSNM17_17450	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TthSNM17_17470	COG0049	tRNA binding
TthSNM17_17500	COG0442	prolyl-tRNA aminoacylation
TthSNM17_17520	COG1115	amino acid carrier protein
TthSNM17_17560	COG1489	DNA binding
TthSNM17_17590	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
TthSNM17_17630	COG0432	Pfam Uncharacterised protein family UPF0047
TthSNM17_17640	COG3253	May function as heme-dependent peroxidase
TthSNM17_17650	COG0668	transmembrane transport
TthSNM17_17670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TthSNM17_17680	COG2217	Heavy metal translocating P-type atpase
TthSNM17_17720	COG0745	RESPONSE REGULATOR receiver
TthSNM17_17730	COG2205	protein histidine kinase activity
TthSNM17_17780	COG2226	methyltransferase
TthSNM17_17820	COG2132	Multicopper oxidase
TthSNM17_17840	COG2217	Heavy metal translocating P-type atpase
TthSNM17_17850	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TthSNM17_17860	COG0822	iron-sulfur transferase activity
TthSNM17_17900	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
TthSNM17_17920	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TthSNM17_17930	COG0284	orotidine-5'-phosphate decarboxylase activity
TthSNM17_17950	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
TthSNM17_17970	COG0416	fatty acid biosynthetic process
TthSNM17_17980	COG3118	belongs to the thioredoxin family
TthSNM17_17990	COG1185	polyribonucleotide nucleotidyltransferase activity
TthSNM17_18000	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TthSNM17_18020	COG0438	transferase activity, transferring glycosyl groups
TthSNM17_18060	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TthSNM17_18090	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TthSNM17_18100	COG3706	GGDEF domain
TthSNM17_18170	COG0437	4 iron, 4 sulfur cluster binding
TthSNM17_18200	COG0825	malonyl-CoA metabolic process
TthSNM17_18210	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
TthSNM17_18280	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
TthSNM17_18330	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TthSNM17_18340	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TthSNM17_18350	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TthSNM17_18360	COG0261	This protein binds to 23S rRNA in the presence of protein L20
TthSNM17_18420	COG0315	cyclic pyranopterin monophosphate synthase activity
TthSNM17_18440	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TthSNM17_18470	COG1694	Mazg nucleotide pyrophosphohydrolase
TthSNM17_18480	COG1803	Methylglyoxal synthase
TthSNM17_18500	COG0301	tRNA thio-modification
TthSNM17_18510	COG0154	amidase activity
TthSNM17_18520	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
TthSNM17_18570	COG2154	pterin-4-alpha-carbinolamine dehydratase
TthSNM17_18580	COG1607	acyl-coa hydrolase
TthSNM17_18600	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
TthSNM17_18630	COG1840	ABC-type Fe3 transport system, periplasmic component
TthSNM17_18660	COG0235	Class ii aldolase
TthSNM17_18670	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TthSNM17_18680	COG0085	RNA polymerase activity
TthSNM17_18700	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TthSNM17_18710	COG1077	Cell shape determining protein MreB Mrl
TthSNM17_18720	COG1418	mRNA catabolic process
TthSNM17_18720	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
TthSNM17_18730	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
TthSNM17_18740	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
TthSNM17_18750	COG1546	Belongs to the CinA family
TthSNM17_18750	COG1058	Belongs to the CinA family
TthSNM17_18760	COG0354	folic acid binding
TthSNM17_18790	COG4948	Mandelate Racemase Muconate Lactonizing
TthSNM17_18890	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
TthSNM17_18910	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TthSNM17_18930	COG0577	efflux transmembrane transporter activity
TthSNM17_18930	COG1136	(ABC) transporter
TthSNM17_18940	COG0446	pyridine nucleotide-disulphide oxidoreductase
TthSNM17_18970	COG0396	ATPase activity
TthSNM17_18980	COG0719	Fe-S assembly protein
TthSNM17_18990	COG0719	Fe-S assembly protein
TthSNM17_19000	COG2146	nitrite reductase [NAD(P)H] activity
TthSNM17_19020	COG0512	Glutamine amidotransferase of anthranilate synthase
TthSNM17_19030	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
TthSNM17_19090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TthSNM17_19100	COG2226	methyltransferase
TthSNM17_19110	COG4603	Belongs to the binding-protein-dependent transport system permease family
TthSNM17_19120	COG1079	Belongs to the binding-protein-dependent transport system permease family
TthSNM17_19160	COG1774	PSP1 C-terminal conserved region
TthSNM17_19170	COG0470	DNA polymerase III
TthSNM17_19210	COG0497	DNA recombination
TthSNM17_19240	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TthSNM17_19270	COG0302	gtp cyclohydrolase
TthSNM17_19320	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TthSNM17_19340	COG0395	ABC-type sugar transport system, permease component
TthSNM17_19350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TthSNM17_19360	COG1131	(ABC) transporter
TthSNM17_19400	COG0556	nucleotide-excision repair
TthSNM17_19410	COG0497	DNA recombination
TthSNM17_19420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
TthSNM17_19430	COG0445	tRNA wobble uridine modification
TthSNM17_19480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TthSNM17_19480	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TthSNM17_19490	COG1543	Belongs to the glycosyl hydrolase 57 family
TthSNM17_19500	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TthSNM17_19510	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
TthSNM17_19520	COG0189	ligase activity
TthSNM17_19550	COG0066	3-isopropylmalate dehydratase activity
TthSNM17_19560	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TthSNM17_19590	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TthSNM17_19600	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TthSNM17_19610	COG1960	acyl-CoA dehydrogenase activity
TthSNM17_19620	COG0163	prenyltransferase activity
TthSNM17_19670	COG1668	transmembrane transport
TthSNM17_19680	COG4555	ABC transporter
TthSNM17_19700	COG2096	Adenosyltransferase
TthSNM17_19730	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TthSNM17_19740	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
TthSNM17_19770	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
TthSNM17_19780	COG0723	plastoquinol--plastocyanin reductase activity
TthSNM17_19830	COG1653	transport
TthSNM17_19840	COG0820	rRNA (adenine-C2-)-methyltransferase activity
TthSNM17_19850	COG1960	acyl-CoA dehydrogenase activity
TthSNM17_19870	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TthSNM17_19970	COG3956	TIGRFAM MazG family protein
TthSNM17_19990	COG0693	protein deglycase activity
TthSNM17_20000	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TthSNM17_20020	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TthSNM17_20030	COG1937	Protein conserved in bacteria
TthSNM17_20050	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TthSNM17_20050	COG0674	pyruvate-flavodoxin oxidoreductase activity
TthSNM17_20080	COG1013	pyruvate-flavodoxin oxidoreductase activity
TthSNM17_20130	COG0205	6-phosphofructokinase activity
TthSNM17_20140	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
TthSNM17_20160	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
TthSNM17_20190	COG0658	competence protein
TthSNM17_20190	COG2333	competence protein COMEC
TthSNM17_20200	COG1475	DNA binding
TthSNM17_20210	COG1192	Involved in chromosome partitioning
TthSNM17_20220	COG0357	Ribosomal RNA small subunit methyltransferase G
TthSNM17_20520	COG0588	phosphoglycerate mutase activity
TthSNM17_20560	COG1028	Short-chain dehydrogenase reductase Sdr
TthSNM17_20580	COG1012	belongs to the aldehyde dehydrogenase family
TthSNM17_20580	COG2030	dehydratase
TthSNM17_20590	COG1028	Short-chain dehydrogenase reductase Sdr
TthSNM17_20610	COG1960	acyl-CoA dehydrogenase activity
TthSNM17_20700	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TthSNM17_20730	COG0739	heme binding
TthSNM17_20750	COG2211	Major facilitator Superfamily
TthSNM17_20770	COG3335	DDE superfamily endonuclease
TthSNM17_20780	COG1797	cobyrinic acid a,c-diamide synthase activity
TthSNM17_20790	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
TthSNM17_20810	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
TthSNM17_20840	COG0588	phosphoglycerate mutase activity
TthSNM17_20850	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
TthSNM17_20890	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
TthSNM17_20980	COG1648	precorrin-2 dehydrogenase activity
TthSNM17_20980	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TthSNM17_20990	COG0778	Nitroreductase
TthSNM17_21030	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TthSNM17_21060	COG1492	cobalamin metabolic process
TthSNM17_21070	COG1785	Belongs to the alkaline phosphatase family
TthSNM17_21120	COG0800	Aldolase
TthSNM17_21130	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
TthSNM17_21190	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
TthSNM17_21200	COG1028	Short-chain dehydrogenase reductase Sdr
TthSNM17_21230	COG1028	Short-chain dehydrogenase reductase Sdr
TthSNM17_21280	COG1175	transmembrane transport
TthSNM17_21300	COG2723	6-phospho-beta-galactosidase activity
TthSNM17_21310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TthSNM17_21360	COG1233	COG1233 Phytoene dehydrogenase and related
TthSNM17_21370	COG0702	epimerase
TthSNM17_21430	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TthSNM17_21450	COG1562	ergosterol biosynthetic process
TthSNM17_21470	COG2124	cytochrome p450
TthSNM17_21520	COG1487	ribonuclease activity
TthSNM17_21540	COG1304	FMN binding
TthSNM17_21580	COG1085	galactose-1-phosphate uridylyltransferase
TthSNM17_21590	COG3345	alpha-galactosidase
TthSNM17_21620	COG1475	DNA binding
TthSNM17_21640	COG1475	DNA binding
TthSNM17_21650	COG1192	Involved in chromosome partitioning
TthSNM17_21690	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TthSNM17_21810	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
TthSNM17_21820	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
TthSNM17_21830	COG1252	NADH dehydrogenase
TthSNM17_21870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TthSNM17_21940	COG2151	metal-sulfur cluster biosynthetic enzyme
TthSNM17_21950	COG2814	Major facilitator Superfamily
TthSNM17_21970	COG0584	glycerophosphoryl diester phosphodiesterase
TthSNM17_21990	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
TthSNM17_22020	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TthSNM17_22050	COG1337	RAMP superfamily
TthSNM17_22170	COG1205	dead DEAH box helicase
TthSNM17_22170	COG1111	helicase
TthSNM17_22220	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TthSNM17_22360	COG2414	aldehyde ferredoxin oxidoreductase
TthSNM17_22380	COG1110	DNA topoisomerase II activity
TthSNM17_22450	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TthSNM17_22460	COG1518	maintenance of DNA repeat elements
TthSNM17_22530	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
TthSNM17_22540	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TthSNM17_22690	COG0395	ABC-type sugar transport system, permease component
TthSNM17_22750	COG0521	Mo-molybdopterin cofactor biosynthetic process
TthSNM17_22760	COG0523	cobalamin synthesis protein
TthSNM17_22800	COG0803	Belongs to the bacterial solute-binding protein 9 family
TthSNM17_23100	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TthSNM17_23110	COG2385	sporulation resulting in formation of a cellular spore
TthSNM17_23190	COG3335	DDE superfamily endonuclease
TthSNM17_23310	COG1074	ATP-dependent DNA helicase activity
TthSNM17_23340	COG1203	CRISPR-associated helicase, Cas3
TthSNM17_23440	COG2197	response regulator
TthSNM17_23470	COG1131	(ABC) transporter
TthSNM17_23570	COG3335	DDE superfamily endonuclease
TthSNM17_23770	COG1192	Involved in chromosome partitioning
TthSNM17_23780	COG1475	DNA binding
TthSNM17_23910	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
TthSNM17_23930	COG3639	organic phosphonate transmembrane transporter activity
TthSNM17_23970	COG3627	carbon phosphorus lyase activity
TthSNM17_23980	COG4107	phosphonate C-P lyase system protein PhnK
TthSNM17_23990	COG4778	phosphonate C-P lyase system protein PhnL
TthSNM17_24000	COG3454	Phosphonate metabolism
TthSNM17_24040	COG1692	metallophosphoesterase
TthSNM17_24050	COG0395	ABC-type sugar transport system, permease component
TthSNM17_24060	COG1175	transmembrane transport
TthSNM17_24070	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
TthSNM17_24140	COG3335	DDE superfamily endonuclease
TthSNM17_24190	COG4876	unkown
TthSNM17_24280	COG4974	Belongs to the 'phage' integrase family
TthSNM17_24320	COG1192	Involved in chromosome partitioning
TthSNM17_24610	COG2079	MmgE PrpD family protein
TthSNM17_24620	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
TthSNM17_t00350	COG0544	peptidyl-prolyl cis-trans isomerase activity