locus-tag	class	description
TVNIR_0001	ENOG4105BZ1	(ABC) transporter
TVNIR_0002	ENOG4108KMV	Glycosyl transferase (Group 1
TVNIR_0020	ENOG4105F5W	AtP-binding protein
TVNIR_0045	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2
TVNIR_0047	ENOG41076QQ	Glycosyl transferase, family 2
TVNIR_0050	ENOG4105KHS	type IV fimbrial pilin protein
TVNIR_0055	ENOG4105C8S	subunit m
TVNIR_0060	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
TVNIR_0061	ENOG4107QKV	phosphomannomutase
TVNIR_0062	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
TVNIR_0068	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
TVNIR_0069	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
TVNIR_0070	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
TVNIR_0071	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
TVNIR_0072	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
TVNIR_0079	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
TVNIR_0080	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
TVNIR_0081	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
TVNIR_0082	ENOG4105CT0	Protein of unknown function, DUF484
TVNIR_0084	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
TVNIR_0085	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
TVNIR_0087	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TVNIR_0089	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
TVNIR_0090	ENOG4105CSR	polyphosphate kinase 2
TVNIR_0091	ENOG4105C8S	subunit m
TVNIR_0092	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TVNIR_0093	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TVNIR_0094	ENOG4105MKQ	Monovalent cation H antiporter subunit C
TVNIR_0095	ENOG4105D65	subunit l
TVNIR_0097	ENOG4105KJM	monovalent cation h antiporter subunit g
TVNIR_0100	ENOG4105C1Q	protoporphyrinogen oxidase
TVNIR_0101	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
TVNIR_0105	ENOG4105W0E	50S ribosomal protein L33
TVNIR_0106	ENOG4105KDC	50s ribosomal protein l28
TVNIR_0107	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
TVNIR_0112	ENOG4105WH1	Two component transcriptional regulator luxr family
TVNIR_0128	ENOG4105BZU	Histidine kinase
TVNIR_0130	ENOG41085AF	Cytochrome
TVNIR_0131	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
TVNIR_0133	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
TVNIR_0136	ENOG4105DSY	exodeoxyribonuclease V, gamma
TVNIR_0137	ENOG4107QKA	exodeoxyribonuclease V beta
TVNIR_0138	ENOG4107QYX	exodeoxyribonuclease v alpha
TVNIR_0140	ENOG41089UC	methyltransferase, type 11
TVNIR_0143	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
TVNIR_0144	ENOG4107QR9	Iron-sulfur cluster binding protein
TVNIR_0145	ENOG4105DAA	L-lactate
TVNIR_0146	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
TVNIR_0148	ENOG4105EMN	RNA polymerase sigma factor
TVNIR_0152	ENOG4108I5C	dEAD DEAH box helicase
TVNIR_0159	ENOG4105EAH	synthase
TVNIR_0160	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
TVNIR_0161	ENOG4105K46	50S ribosomal protein l27
TVNIR_0162	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TVNIR_0163	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
TVNIR_0164	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
TVNIR_0166	ENOG4105CJR	Integral membrane protein (MviN
TVNIR_0167	ENOG4105DTN	riboflavin biosynthesis protein ribF
TVNIR_0168	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
TVNIR_0169	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
TVNIR_0170	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
TVNIR_0171	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
TVNIR_0173	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TVNIR_0174	ENOG4105BZU	Histidine kinase
TVNIR_0183	ENOG4105C0P	Mg chelatase subunit ChlI
TVNIR_0184	ENOG4105W0Z	cytoplasmic protein
TVNIR_0188	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TVNIR_0189	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
TVNIR_0192	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
TVNIR_0193	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
TVNIR_0196	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
TVNIR_0197	ENOG4105C58	cytochrome c oxidase accessory protein ccog
TVNIR_0199	ENOG4105C59	p-type ATPase
TVNIR_0205	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TVNIR_0207	ENOG4105CAK	Cell division ATP-binding protein ftsE
TVNIR_0208	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
TVNIR_0211	ENOG4106H78	methyltransferase
TVNIR_0215	ENOG4105WH1	Two component transcriptional regulator luxr family
TVNIR_0217	ENOG4105VXR	cytoplasmic protein
TVNIR_0220	ENOG4107SC1	transglycosylase
TVNIR_0221	ENOG4108R99	pseudouridine synthase
TVNIR_0224	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
TVNIR_0225	ENOG4105C6K	Malic enzyme
TVNIR_0227	ENOG4105VFB	Binds the 23S rRNA (By similarity)
TVNIR_0228	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
TVNIR_0232	ENOG4105C12	Phosphoribosylglycinamide synthetase
TVNIR_0236	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
TVNIR_0237	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
TVNIR_0239	ENOG4105C3R	Methionine synthase
TVNIR_0242	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
TVNIR_0250	ENOG4105F8J	Adenylate Guanylate cyclase
TVNIR_0251	ENOG4105ECY	inositol monophosphatase
TVNIR_0255	ENOG4105C5H	ABC transporter
TVNIR_0256	ENOG4107S7U	Sulfide dehydrogenase
TVNIR_0261	ENOG4105DA4	cytochrome c-type biogenesis protein
TVNIR_0262	ENOG4107QX9	Thiol disulfide interChange protein
TVNIR_0263	ENOG4105KWW	Biogenesis protein
TVNIR_0265	ENOG41060IM	Heme exporter protein
TVNIR_0267	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
TVNIR_0268	ENOG4105DA4	cytochrome c-type biogenesis protein
TVNIR_0269	ENOG4107QX9	Thiol disulfide interChange protein
TVNIR_0271	ENOG4105BZU	Histidine kinase
TVNIR_0272	ENOG4105WH1	Two component transcriptional regulator luxr family
TVNIR_0275	ENOG4105D9M	gamma-glutamylcysteine synthetase
TVNIR_0276	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
TVNIR_0277	ENOG4105BZS	acriflavin resistance protein
TVNIR_0278	ENOG4105E0X	reductase
TVNIR_0279	ENOG4107STW	synthase
TVNIR_0288	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
TVNIR_0289	ENOG4107RK2	ADP-ribose diphosphatase NudE
TVNIR_0291	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
TVNIR_0295	ENOG4108VIA	integral membrane protein
TVNIR_0297	ENOG4105II7	pyrroline-5-carboxylate reductase
TVNIR_0298	ENOG4105DFA	alanine racemase domain protein
TVNIR_0299	ENOG4105CZX	twitching motility protein
TVNIR_0300	ENOG4105CZX	twitching motility protein
TVNIR_0301	ENOG4105CZX	twitching motility protein
TVNIR_0302	ENOG4105CD3	dihydroorotase
TVNIR_0303	ENOG4105CXT	aspartate transcarbamylase
TVNIR_0306	ENOG4108UJU	UPF0301 protein
TVNIR_0307	ENOG4105WQ5	TonB family
TVNIR_0310	ENOG41081YB	ApbE family
TVNIR_0311	ENOG4105D7Z	glutathione synthase
TVNIR_0320	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TVNIR_0324	ENOG4107TPS	domain protein
TVNIR_0332	ENOG4107QN2	dihydrolipoyl dehydrogenase
TVNIR_0336	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
TVNIR_0337	ENOG4105SYT	Methylenetetrahydrofolate reductase
TVNIR_0338	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
TVNIR_0339	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
TVNIR_0340	ENOG4105CV1	Transketolase (EC 2.2.1.1)
TVNIR_0341	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
TVNIR_0342	ENOG4105BZA	Phosphoglycerate kinase
TVNIR_0343	ENOG4105CA9	Pyruvate kinase
TVNIR_0344	ENOG4105D2N	Aldolase
TVNIR_0346	ENOG4105C8V	SAICAR synthetase
TVNIR_0347	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
TVNIR_0348	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
TVNIR_0349	ENOG4107Y49	methyltransferase
TVNIR_0353	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TVNIR_0354	ENOG4105CRQ	synthase (Component I)
TVNIR_0356	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
TVNIR_0358	ENOG4105DDQ	anthranilate synthase
TVNIR_0359	ENOG4108I0Q	anthranilate phosphoribosyltransferase
TVNIR_0360	ENOG4105DK0	Indole-3-glycerol phosphate synthase
TVNIR_0361	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
TVNIR_0362	ENOG4108UKZ	OsmC family
TVNIR_0363	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
TVNIR_0364	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
TVNIR_0372	ENOG4105EMN	RNA polymerase sigma factor
TVNIR_0375	ENOG4108S0S	Nucleotidyl transferase
TVNIR_0376	ENOG4105EHM	Aminoglycoside phosphotransferase
TVNIR_0377	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
TVNIR_0378	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
TVNIR_0379	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
TVNIR_0380	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
TVNIR_0390	ENOG4105CAS	nag kinase
TVNIR_0394	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
TVNIR_0395	ENOG4105W5Q	DNA repair protein (RadC
TVNIR_0396	ENOG4105C0A	alcohol dehydrogenase
TVNIR_0397	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
TVNIR_0402	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
TVNIR_0403	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
TVNIR_0405	ENOG4105MJ2	Competence protein
TVNIR_0406	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
TVNIR_0407	ENOG4108ZG0	Ompa motb domain protein
TVNIR_0408	ENOG4105E2X	shikimate dehydrogenase
TVNIR_0409	ENOG4105D52	delta-aminolevulinic acid dehydratase
TVNIR_0410	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
TVNIR_0412	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
TVNIR_0414	ENOG4108RPN	Protein smg homolog
TVNIR_0415	ENOG4105C79	DNA protecting protein DprA
TVNIR_0417	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
TVNIR_0418	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
TVNIR_0419	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
TVNIR_0421	ENOG4105ES5	Histidine kinase
TVNIR_0422	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TVNIR_0423	ENOG4105C1A	potassium transporter peripheral membrane
TVNIR_0429	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
TVNIR_0431	ENOG4107ZVW	dihydroneopterin aldolase
TVNIR_0432	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TVNIR_0433	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TVNIR_0435	ENOG4108YZA	Nitrogen regulatory protein pii
TVNIR_0437	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TVNIR_0447	ENOG4108WUH	Transcriptional regulator, TetR family
TVNIR_0449	ENOG4107QZM	n-acetylglutamate synthase
TVNIR_0452	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
TVNIR_0454	ENOG4107R11	Transcriptional regulator
TVNIR_0455	ENOG4105EGS	Mechanosensitive ion channel
TVNIR_0459	ENOG4105C01	Dihydroxy-acid dehydratase
TVNIR_0460	ENOG4108V1T	peptidylprolyl cis-trans isomerase
TVNIR_0463	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
TVNIR_0464	ENOG4105C4R	Atp-dependent dna helicase
TVNIR_0470	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
TVNIR_0472	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
TVNIR_0473	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
TVNIR_0474	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
TVNIR_0476	ENOG4107QX9	Thiol disulfide interChange protein
TVNIR_0477	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
TVNIR_0478	ENOG4105VF7	tolerance protein
TVNIR_0482	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
TVNIR_0483	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
TVNIR_0484	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
TVNIR_0487	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TVNIR_0491	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TVNIR_0493	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TVNIR_0496	ENOG4105MA0	exported protein
TVNIR_0497	ENOG4105CFU	surface antigen
TVNIR_0499	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
TVNIR_0500	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
TVNIR_0502	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
TVNIR_0503	ENOG4105CM2	brancheD-chain amino acid aminotransferase
TVNIR_0505	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TVNIR_0508	ENOG4105BZU	Histidine kinase
TVNIR_0517	ENOG4108JCI	Transcriptional regulator
TVNIR_0519	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
TVNIR_0522	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
TVNIR_0537	ENOG4108NEV	two component transcriptional regulator, LytTR family
TVNIR_0538	ENOG4108HRK	Histidine kinase
TVNIR_0540	ENOG4105BZU	Histidine kinase
TVNIR_0541	ENOG4105E6M	Sulphatase-modifying factor protein
TVNIR_0542	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TVNIR_0543	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
TVNIR_0549	ENOG4105DP0	ferredoxin-NADP reductase
TVNIR_0551	ENOG4107S7U	Sulfide dehydrogenase
TVNIR_0556	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
TVNIR_0557	ENOG4105BZU	Histidine kinase
TVNIR_0558	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
TVNIR_0562	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
TVNIR_0563	ENOG4105D1S	lipid A biosynthesis
TVNIR_0567	ENOG4105BZ1	(ABC) transporter
TVNIR_0569	ENOG4105CHH	sulfate transporter
TVNIR_0571	ENOG4105BZU	Histidine kinase
TVNIR_0575	ENOG4105CNG	UPF0061 protein
TVNIR_0576	ENOG4105UBK	short-chain dehydrogenase reductase
TVNIR_0579	ENOG4108UPT	UPF0178 protein
TVNIR_0584	ENOG4105CE1	Ferrous iron transport protein b
TVNIR_0593	ENOG4105E2Y	ABC, transporter
TVNIR_0596	ENOG4107ENK	receptor
TVNIR_0597	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
TVNIR_0598	ENOG4105EHG	Permease protein
TVNIR_0599	ENOG4107R4I	Periplasmic binding protein
TVNIR_0600	ENOG4106QJH	hemin transport protein
TVNIR_0602	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
TVNIR_0616	ENOG4105CY0	Metallo-Beta-Lactamase
TVNIR_0625	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
TVNIR_0628	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
TVNIR_0631	ENOG4105YAJ	CopG Arc MetJ
TVNIR_0634	ENOG4105C30	Nad-dependent epimerase dehydratase
TVNIR_0639	ENOG4105YXB	Toxic component of a toxin-antitoxin (TA) module. A
TVNIR_0641	ENOG4105C30	Nad-dependent epimerase dehydratase
TVNIR_0650	ENOG4105VUH	addiction module killer protein
TVNIR_0653	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
TVNIR_0671	ENOG4107QQG	Dehydrogenase
TVNIR_0674	ENOG4105PF0	Antitoxin component of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin
TVNIR_0677	ENOG4105C30	Nad-dependent epimerase dehydratase
TVNIR_0680	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
TVNIR_0681	ENOG4105CY0	Metallo-Beta-Lactamase
TVNIR_0686	ENOG4107QQG	Dehydrogenase
TVNIR_0689	ENOG4105J5G	Transferase hexapeptide repeat containing protein
TVNIR_0691	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
TVNIR_0699	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
TVNIR_0709	ENOG4107S90	membrAne
TVNIR_0728	ENOG4105WJ3	XRE family Transcriptional regulator
TVNIR_0732	ENOG4107S90	membrAne
TVNIR_0735	ENOG4107S90	membrAne
TVNIR_0742	ENOG4107S90	membrAne
TVNIR_0746	ENOG4107S90	membrAne
TVNIR_0763	ENOG4107S90	membrAne
TVNIR_0773	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
TVNIR_0777	ENOG4105YES	addiction module antidote protein
TVNIR_0789	ENOG4105VT3	DNA binding domain protein, excisionase family
TVNIR_0796	ENOG41080VW	acetyltransferase
TVNIR_0804	ENOG4105E0F	Histidine kinase
TVNIR_0805	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
TVNIR_0808	ENOG4105EHV	domain protein
TVNIR_0809	ENOG4107QMP	dna polymerase iii subunits gamma and tau
TVNIR_0810	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
TVNIR_0811	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
TVNIR_0812	ENOG4107YU2	histidine triad (hIT) protein
TVNIR_0815	ENOG41090A4	Pterin carbinolamine dehydratase
TVNIR_0817	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
TVNIR_0818	ENOG4108IYU	L-aspartate oxidase
TVNIR_0819	ENOG4105EMN	RNA polymerase sigma factor
TVNIR_0820	ENOG41069E1	anti sigma-E protein RseA
TVNIR_0823	ENOG4105C0H	protease
TVNIR_0825	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
TVNIR_0826	ENOG4105C3F	Signal peptidase i
TVNIR_0829	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
TVNIR_0831	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
TVNIR_0832	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
TVNIR_0833	ENOG4105C6T	cysteine synthase
TVNIR_0835	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
TVNIR_0837	ENOG4109015	Biopolymer transport protein exbD tolR
TVNIR_0838	ENOG4105BZ1	(ABC) transporter
TVNIR_0840	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
TVNIR_0841	ENOG4105W49	UPF0434 protein
TVNIR_0843	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
TVNIR_0846	ENOG4107E2E	PKHD-type hydroxylase
TVNIR_0848	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
TVNIR_0850	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
TVNIR_0853	ENOG4105CXT	aspartate transcarbamylase
TVNIR_0855	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
TVNIR_0857	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
TVNIR_0858	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
TVNIR_0859	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
TVNIR_0860	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
TVNIR_0865	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
TVNIR_0871	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
TVNIR_0872	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
TVNIR_0873	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
TVNIR_0876	ENOG4105CUT	histidyl-tRNA synthetase
TVNIR_0878	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
TVNIR_0879	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
TVNIR_0882	ENOG4105D7X	high-affinity nickel-transporter
TVNIR_0884	ENOG4105C8N	cysteinyl-tRNA synthetase
TVNIR_0885	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
TVNIR_0886	ENOG4105BZU	Histidine kinase
TVNIR_0887	ENOG4108Q6X	Aspartoacylase (EC 3.5.1.15)
TVNIR_0889	ENOG4105BZU	Histidine kinase
TVNIR_0890	ENOG4105DP0	ferredoxin-NADP reductase
TVNIR_0891	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
TVNIR_0892	ENOG4105BZU	Histidine kinase
TVNIR_0894	ENOG4108V1T	peptidylprolyl cis-trans isomerase
TVNIR_0897	ENOG4105C8U	phosphate abc transporter
TVNIR_0898	ENOG4105E2Z	phosphate ABC transporter (Permease
TVNIR_0899	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
TVNIR_0901	ENOG4105CGH	5'-nucleotidase
TVNIR_0902	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
TVNIR_0903	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
TVNIR_0907	ENOG4105EUB	pirin domain protein
TVNIR_0909	ENOG41082AG	Plasmid maintenance system antidote protein
TVNIR_0911	ENOG4105D70	Integrase catalytic subunit
TVNIR_0916	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TVNIR_0917	ENOG4105F5W	AtP-binding protein
TVNIR_0923	ENOG4105CFI	type iii restriction protein res subunit
TVNIR_0934	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
TVNIR_0935	ENOG4105S7S	phosphonate abc transporter
TVNIR_0936	ENOG4108VA1	ABC transporter
TVNIR_0938	ENOG4105EM7	Selenocysteine-specific translation elongation factor
TVNIR_0943	ENOG4108YZY	peptidylprolyl cis-trans isomerase
TVNIR_0948	ENOG4107SFQ	iron-sulfur binding
TVNIR_0949	ENOG4105C3J	Cysteine desulfurase
TVNIR_0953	ENOG4105BZU	Histidine kinase
TVNIR_0954	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TVNIR_0955	ENOG4105KHC	sulfurtransferase
TVNIR_0962	ENOG4107R5R	arsenical pump membrane protein
TVNIR_0968	ENOG4105F4R	Transcriptional regulator mode
TVNIR_0969	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
TVNIR_0970	ENOG4105E0C	molybdate abc transporter
TVNIR_0971	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
TVNIR_0976	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
TVNIR_0977	ENOG4107QY8	reductase
TVNIR_0978	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
TVNIR_0979	ENOG4108MG3	formate dehydrogenase
TVNIR_0980	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
TVNIR_0981	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
TVNIR_0983	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
TVNIR_0987	ENOG4105CA9	Pyruvate kinase
TVNIR_0990	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
TVNIR_0991	ENOG4107YIM	Involved in the transcription termination process (By similarity)
TVNIR_0992	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
TVNIR_0996	ENOG4108ZAI	phosphatidylglycerophosphatase a
TVNIR_0997	ENOG4108Z9W	Outer membrane porin
TVNIR_1005	ENOG4105CBC	glutamate synthase
TVNIR_1013	ENOG4105CIZ	coA-substrate-specific enzyme activase
TVNIR_1020	ENOG4105BZU	Histidine kinase
TVNIR_1021	ENOG4105E7U	AraC family transcriptional regulator
TVNIR_1024	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
TVNIR_1028	ENOG4105E18	UPF0276 protein
TVNIR_1034	ENOG4107QPN	acyl-Coa dehydrogenase
TVNIR_1035	ENOG4105CHU	acetyl-coa acetyltransferase
TVNIR_1036	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
TVNIR_1037	ENOG4108IQE	Amp-dependent synthetase and ligase
TVNIR_1039	ENOG4105E66	phosphoriboisomerase A
TVNIR_1040	ENOG4105C7B	Threonine dehydratase
TVNIR_1043	ENOG4105CVR	type I restriction-modification system
TVNIR_1045	ENOG4107XZC	Restriction modification system DNA (Specificity
TVNIR_1052	ENOG41065SU	Two-component system sensor kinase
TVNIR_1056	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
TVNIR_1057	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
TVNIR_1060	ENOG4105E07	UPF0149 protein
TVNIR_1061	ENOG4107RAQ	aminopeptidase
TVNIR_1062	ENOG4105D0A	hydroxylase
TVNIR_1063	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
TVNIR_1064	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
TVNIR_1065	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
TVNIR_1066	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TVNIR_1068	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TVNIR_1069	ENOG41080IJ	Diacylglycerol kinase
TVNIR_1072	ENOG4105FDK	ABC transporter
TVNIR_1073	ENOG4105FAV	ABC, transporter
TVNIR_1076	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
TVNIR_1077	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
TVNIR_1078	ENOG4105C7Z	Conserved Protein
TVNIR_1091	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TVNIR_1095	ENOG4105CEY	Amp-dependent synthetase and ligase
TVNIR_1100	ENOG4105GR3	Histidine kinase
TVNIR_1106	ENOG4107R16	Multicopper oxidase
TVNIR_1110	ENOG41083IP	HIT family
TVNIR_1112	ENOG4105BZP	glycoside hydrolase 15-related
TVNIR_1119	ENOG4108JIG	Anaerobic dehydrogenase
TVNIR_1131	ENOG4105EKQ	RNA-directed DNA polymerase
TVNIR_1147	ENOG4105C4R	Atp-dependent dna helicase
TVNIR_1154	ENOG41084HI	prevent-host-death family
TVNIR_1160	ENOG4108Z7F	N-acetyltransferase
TVNIR_1162	ENOG4107QRS	glycosyltransferase group 2 family protein
TVNIR_1170	ENOG4106RHG	Yeca family
TVNIR_1171	ENOG4105EKE	dihydroorotase
TVNIR_1175	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
TVNIR_1178	ENOG4105D7A	ATP-binding protein
TVNIR_1184	ENOG4108RU0	short-chain dehydrogenase reductase
TVNIR_1185	ENOG4108UVJ	appr-1-p processing domain protein
TVNIR_1188	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
TVNIR_1191	ENOG4105DRS	transport system, permease
TVNIR_1193	ENOG4105EUB	pirin domain protein
TVNIR_1195	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
TVNIR_1199	ENOG4105BZS	acriflavin resistance protein
TVNIR_1200	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
TVNIR_1202	ENOG4105D78	K07001 NTE family protein
TVNIR_1203	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TVNIR_1208	ENOG4108YXU	transcriptional regulator AsnC family
TVNIR_1210	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
TVNIR_1211	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TVNIR_1212	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
TVNIR_1213	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
TVNIR_1214	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
TVNIR_1218	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
TVNIR_1219	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
TVNIR_1220	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
TVNIR_1221	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
TVNIR_1222	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
TVNIR_1223	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
TVNIR_1225	ENOG4105E96	Colicin v production protein
TVNIR_1226	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
TVNIR_1227	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
TVNIR_1228	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
TVNIR_1229	ENOG4105F8C	transglutaminase domain-containing protein
TVNIR_1231	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TVNIR_1232	ENOG4105CY3	ABC transporter, permease
TVNIR_1233	ENOG4105DHJ	ABC, transporter
TVNIR_1234	ENOG4105DY2	Paraquat-inducible protein b
TVNIR_1236	ENOG4108Z6B	deaminase
TVNIR_1237	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
TVNIR_1238	ENOG4105CHR	reductase
TVNIR_1241	ENOG4108NVM	synthesis repressor PhaR
TVNIR_1242	ENOG4105CHU	acetyl-coa acetyltransferase
TVNIR_1244	ENOG4108U4D	synthase) subunit
TVNIR_1245	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
TVNIR_1249	ENOG4105CAF	HipA N-terminal domain protein
TVNIR_1253	ENOG41088T4	Helicase IV
TVNIR_1256	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
TVNIR_1257	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
TVNIR_1259	ENOG4105FQT	
TVNIR_1262	ENOG4108S24	Fumarate reduCtase
TVNIR_1263	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
TVNIR_1264	ENOG4105E33	succinate dehydrogenase
TVNIR_1265	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
TVNIR_1268	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
TVNIR_1270	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
TVNIR_1276	ENOG410902C	phosphohistidine phosphatase, SixA
TVNIR_1278	ENOG4105C9X	ppx gppa phosphatase
TVNIR_1280	ENOG4105DBV	ornithine carbamoyltransferase
TVNIR_1281	ENOG4105C8Y	Acetylornithine aminotransferase
TVNIR_1282	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
TVNIR_1283	ENOG4105C8P	)-transporter
TVNIR_1289	ENOG4105DJ9	glucan biosynthesis protein
TVNIR_1290	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
TVNIR_1291	ENOG4105CPW	cytochrome b561
TVNIR_1300	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TVNIR_1301	ENOG4105D0M	Protease HtpX homolog
TVNIR_1302	ENOG4108YZY	peptidylprolyl cis-trans isomerase
TVNIR_1309	ENOG4105NBF	ammecr1 domain protein
TVNIR_1310	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
TVNIR_1313	ENOG4105F71	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
TVNIR_1314	ENOG4105MRR	Transcriptional regulator (By similarity)
TVNIR_1316	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
TVNIR_1319	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
TVNIR_1321	ENOG4108JJB	ABC transporter
TVNIR_1322	ENOG4107R37	Glutamate dehydrogenase
TVNIR_1325	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
TVNIR_1326	ENOG4108JNI	Alpha beta hydrolase
TVNIR_1329	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
TVNIR_1330	ENOG4108BGM	Quinol dehydrogenase periplasmic component
TVNIR_1331	ENOG4105GXZ	Ferredoxin-type protein NapH
TVNIR_1335	ENOG41063C6	UPF0235 protein
TVNIR_1337	ENOG4105C26	Dehydrogenase
TVNIR_1343	ENOG41080XP	Cbs domain
TVNIR_1344	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
TVNIR_1351	ENOG4105EYF	MMPL domain protein
TVNIR_1356	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
TVNIR_1357	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
TVNIR_1358	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
TVNIR_1359	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
TVNIR_1362	ENOG4105CX6	glutaminyL-tRNA synthetase
TVNIR_1363	ENOG4108ZXC	Two component transcriptional regulator, luxr family
TVNIR_1364	ENOG4105BZU	Histidine kinase
TVNIR_1369	ENOG4108UHJ	MAF-like protein
TVNIR_1370	ENOG4107QSA	Oxaloacetate decarboxylase
TVNIR_1371	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
TVNIR_1373	ENOG4105VGS	50s ribosomal protein l32
TVNIR_1374	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
TVNIR_1375	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
TVNIR_1376	ENOG41080ZE	Adenylate cyclase
TVNIR_1377	ENOG4105E50	uracil-dna glycosylase
TVNIR_1378	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
TVNIR_1379	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
TVNIR_1380	ENOG4105ESV	Glycosyl transferase, family 4
TVNIR_1384	ENOG4105D75	Capsular exopolysaccharide family
TVNIR_1388	ENOG4108151	Beta-lactamase domain protein
TVNIR_1390	ENOG4105BZN	citrate synthase
TVNIR_1405	ENOG4105BZU	Histidine kinase
TVNIR_1408	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
TVNIR_1409	ENOG4107QMS	site-determining protein
TVNIR_1410	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
TVNIR_1412	ENOG4105D8X	mechanosensitive ion channel
TVNIR_1414	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
TVNIR_1415	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
TVNIR_1417	ENOG4107S5T	Carbohydrate kinase
TVNIR_1418	ENOG4107YRI	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
TVNIR_1419	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
TVNIR_1420	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
TVNIR_1421	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
TVNIR_1422	ENOG4107TF3	peptidylprolyl cis-trans isomerase
TVNIR_1423	ENOG4105K9H	YciI-like protein
TVNIR_1424	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
TVNIR_1425	ENOG4108Z4T	Peptidase M50
TVNIR_1428	ENOG4105C31	Tryptophanyl-tRNA synthetase
TVNIR_1430	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
TVNIR_1432	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
TVNIR_1433	ENOG4105FE9	pseudouridine synthase
TVNIR_1437	ENOG4105CRK	lysyL-tRNA synthetase
TVNIR_1440	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TVNIR_1444	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
TVNIR_1445	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
TVNIR_1446	ENOG4105E33	succinate dehydrogenase
TVNIR_1448	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
TVNIR_1450	ENOG4108Z4U	Ferredoxin
TVNIR_1451	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
TVNIR_1452	ENOG4105CEV	competence damage-inducible protein
TVNIR_1453	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
TVNIR_1454	ENOG4105Y3E	Modulates RecA activity (By similarity)
TVNIR_1455	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
TVNIR_1456	ENOG4105CFH	Aspartokinase
TVNIR_1457	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
TVNIR_1458	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
TVNIR_1461	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
TVNIR_1485	ENOG41063ZP	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
TVNIR_1486	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
TVNIR_1488	ENOG41084EC	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
TVNIR_1499	ENOG4105BZU	Histidine kinase
TVNIR_1502	ENOG4105VN1	Heat shock protein
TVNIR_1505	ENOG4105C5H	ABC transporter
TVNIR_1507	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
TVNIR_1510	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
TVNIR_1515	ENOG4105UBK	short-chain dehydrogenase reductase
TVNIR_1516	ENOG4105BZU	Histidine kinase
TVNIR_1517	ENOG4108ZXC	Two component transcriptional regulator, luxr family
TVNIR_1518	ENOG4107S11	squalene-associated FAD-dependent desaturase
TVNIR_1521	ENOG4105CGY	Dna recombination protein
TVNIR_1522	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TVNIR_1523	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
TVNIR_1524	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
TVNIR_1527	ENOG4105VEQ	Cold shock protein
TVNIR_1528	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
TVNIR_1529	ENOG4105CBC	glutamate synthase
TVNIR_1530	ENOG4105CCT	upf0313 protein
TVNIR_1531	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
TVNIR_1532	ENOG4105DR5	peptidase
TVNIR_1533	ENOG4105E3A	(ABC) transporter
TVNIR_1534	ENOG4105DA5	(ABC) transporter
TVNIR_1535	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
TVNIR_1538	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TVNIR_1540	ENOG4105N7H	Cytochrome
TVNIR_1542	ENOG4105MW3	Cytochrome
TVNIR_1543	ENOG4107S7U	Sulfide dehydrogenase
TVNIR_1546	ENOG4105BZU	Histidine kinase
TVNIR_1554	ENOG4107RQ2	Cytochrome c oxidase, subunit I
TVNIR_1568	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
TVNIR_1569	ENOG4105EZE	Cupin 4 family protein
TVNIR_1570	ENOG4107QTF	adenylosuccinate lyase
TVNIR_1572	ENOG4107QM5	aconitate hydratase
TVNIR_1573	ENOG41075W9	High frequency lysogenization protein HflD homolog
TVNIR_1574	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
TVNIR_1577	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
TVNIR_1578	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TVNIR_1579	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
TVNIR_1580	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
TVNIR_1581	ENOG4105CHR	reductase
TVNIR_1582	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
TVNIR_1583	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
TVNIR_1585	ENOG4105F0I	Aminotransferase
TVNIR_1586	ENOG4105HHA	aminodeoxychorismate lyase
TVNIR_1587	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
TVNIR_1588	ENOG4107QRG	dna polymerase iii
TVNIR_1591	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
TVNIR_1603	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
TVNIR_1604	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
TVNIR_1608	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
TVNIR_1610	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
TVNIR_1611	ENOG4105CHM	Aminotransferase
TVNIR_1612	ENOG4105CHJ	isochorismatase hydrolase
TVNIR_1613	ENOG4105EUB	pirin domain protein
TVNIR_1614	ENOG4105JQN	Transcriptional regulator
TVNIR_1622	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TVNIR_1623	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TVNIR_1630	ENOG4108JQB	penicillin-binding protein 1C
TVNIR_1631	ENOG4105DN3	alpha-2-macroglobulin domain protein
TVNIR_1636	ENOG4105CIG	ABC transporter
TVNIR_1637	ENOG4108T0W	nitrous oxide maturation protein NosY
TVNIR_1642	ENOG4105Y7H	Cytochrome
TVNIR_1643	ENOG4106P6N	cytochrome d1 heme region
TVNIR_1644	ENOG4108UMR	transcriptional regulator AsnC family
TVNIR_1646	ENOG4108ZGY	Transcriptional regulator (AsnC family)
TVNIR_1647	ENOG4108UMR	transcriptional regulator AsnC family
TVNIR_1648	ENOG4107ZBH	radical SAM domain protein
TVNIR_1650	ENOG4105F64	nitrite reductase
TVNIR_1656	ENOG4105DSQ	Nitric oxide reductase
TVNIR_1657	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
TVNIR_1660	ENOG4105E4F	Isochorismate synthase
TVNIR_1661	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
TVNIR_1662	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
TVNIR_1663	ENOG4108IPT	Naphthoate synthase
TVNIR_1664	ENOG4105DNI	Converts SHCHC to OSB (By similarity)
TVNIR_1665	ENOG4105CEY	Amp-dependent synthetase and ligase
TVNIR_1666	ENOG4105KA0	thioesterase Superfamily protein
TVNIR_1676	ENOG4107QI6	Cysteine desulfurase
TVNIR_1679	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
TVNIR_1681	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
TVNIR_1691	ENOG4106H3A	restriction
TVNIR_1705	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
TVNIR_1709	ENOG41082J7	Rhodanese domain protein
TVNIR_1714	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
TVNIR_1715	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
TVNIR_1716	ENOG4107YV9	domain protein
TVNIR_1739	ENOG4105NVB	glycoside hydrolase, family 19
TVNIR_1748	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
TVNIR_1749	ENOG41076YT	nitrate reductase, gamma subunit
TVNIR_1750	ENOG4105R3A	Nitrate reductase
TVNIR_1751	ENOG4108IUE	nitrate reductase beta subunit
TVNIR_1752	ENOG4105CRU	nitrate reductase, alpha subunit
TVNIR_1753	ENOG4105DQQ	Major facilitator superfamily MFS_1
TVNIR_1756	ENOG4105BZU	Histidine kinase
TVNIR_1757	ENOG4105WH1	Two component transcriptional regulator luxr family
TVNIR_1758	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
TVNIR_1761	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TVNIR_1766	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
TVNIR_1767	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
TVNIR_1773	ENOG4105CFP	Peptidase U32
TVNIR_1774	ENOG4106RZ4	Peptidase U32
TVNIR_1775	ENOG4105XPQ	lipid carrier protein
TVNIR_1780	ENOG4105CKI	cobalamin synthesis protein
TVNIR_1787	ENOG4107QYG	anthranilate phosphoribosyltransferase
TVNIR_1789	ENOG4105DH7	May be involved in recombination (By similarity)
TVNIR_1801	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
TVNIR_1802	ENOG4105KQC	Competence protein
TVNIR_1803	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
TVNIR_1804	ENOG4105CFV	Tetratricopeptide repeat protein
TVNIR_1805	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
TVNIR_1806	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
TVNIR_1807	ENOG4105CAT	Cytidine monophosphate kinase
TVNIR_1808	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
TVNIR_1810	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TVNIR_1811	ENOG4105CQC	Prephenate dehydratase
TVNIR_1813	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
TVNIR_1814	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TVNIR_1815	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
TVNIR_1816	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
TVNIR_1818	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TVNIR_1819	ENOG4105D60	lipoprotein releasing system transmembrane protein
TVNIR_1821	ENOG4105DWY	Agmatine deiminase
TVNIR_1824	ENOG4108JA2	transcriptioN-repair coupling factor
TVNIR_1827	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
TVNIR_1828	ENOG4105EI2	Pseudouridine synthase
TVNIR_1830	ENOG4105C03	ribonuclease
TVNIR_1831	ENOG4105KJF	protein tyrosine phosphatase
TVNIR_1832	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
TVNIR_1835	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
TVNIR_1836	ENOG4107QQG	Dehydrogenase
TVNIR_1837	ENOG4108Z4V	iron-sulfur cluster assembly
TVNIR_1839	ENOG4105VG1	fes assembly suf system protein
TVNIR_1841	ENOG4105C3K	feS assembly ATPase SufC
TVNIR_1842	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
TVNIR_1844	ENOG4105KPV	Transcriptional regulator
TVNIR_1845	ENOG41066HZ	AIG2-like family
TVNIR_1846	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
TVNIR_1847	ENOG4105KUZ	arsenate reductase
TVNIR_1849	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
TVNIR_1850	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
TVNIR_1853	ENOG4105DZR	Type I site-specific deoxyribonuclease
TVNIR_1854	ENOG4105CB5	ATP-dependent DNA helicase recG
TVNIR_1856	ENOG4105CB5	ATP-dependent DNA helicase recG
TVNIR_1857	ENOG4105ESI	atpase involved in dna repair
TVNIR_1873	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
TVNIR_1874	ENOG4105C1A	potassium transporter peripheral membrane
TVNIR_1878	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
TVNIR_1880	ENOG4107F83	nucleotidyltransferase DNA polymerase involved in DNA
TVNIR_1883	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
TVNIR_1885	ENOG4105DF9	Lipoate-protein, ligase
TVNIR_1886	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
TVNIR_1887	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
TVNIR_1888	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
TVNIR_1889	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
TVNIR_1890	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
TVNIR_1891	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
TVNIR_1892	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
TVNIR_1893	ENOG4105C0B	DNA polymerase III (alpha subunit)
TVNIR_1894	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TVNIR_1895	ENOG4105CK5	oxidoreductase
TVNIR_1897	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
TVNIR_1900	ENOG4105ESV	Glycosyl transferase, family 4
TVNIR_1908	ENOG4105EY8	ABC transporter
TVNIR_1913	ENOG4107QRS	glycosyltransferase group 2 family protein
TVNIR_1914	ENOG4105GVR	general secretion pathway protein D
TVNIR_1918	ENOG4108RTD	type II secretion system protein K
TVNIR_1919	ENOG41069G9	General secretion pathway protein J
TVNIR_1921	ENOG4105VWV	general secretion pathway protein h
TVNIR_1922	ENOG4108VAU	general secretion pathway protein G
TVNIR_1923	ENOG4105D7Q	type ii secretion system
TVNIR_1924	ENOG4107QHF	type ii secretion system protein e
TVNIR_1925	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
TVNIR_1926	ENOG4108KBE	Glycosyl transferase, family 2
TVNIR_1927	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
TVNIR_1929	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
TVNIR_1933	ENOG4106D4I	domain protein
TVNIR_1934	ENOG4107VRP	DNA repair exonuclease
TVNIR_1938	ENOG4105E9H	Lytic Murein transglycosylase
TVNIR_1939	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
TVNIR_1943	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TVNIR_1944	ENOG4105C8S	subunit m
TVNIR_1945	ENOG4105D65	subunit l
TVNIR_1946	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TVNIR_1948	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TVNIR_1950	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
TVNIR_1951	ENOG4108IEH	NADH dehydrogenase subunit g
TVNIR_1954	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TVNIR_1955	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TVNIR_1956	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TVNIR_1957	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TVNIR_1960	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
TVNIR_1961	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
TVNIR_1965	ENOG4105DZP	Membrane-associated zinc metalloprotease
TVNIR_1966	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
TVNIR_1967	ENOG4105KNE	Phosphatidate cytidylyltransferase
TVNIR_1968	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
TVNIR_1969	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
TVNIR_1970	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
TVNIR_1971	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
TVNIR_1972	ENOG4105CE9	30S ribosomal protein S2
TVNIR_1973	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
TVNIR_1974	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
TVNIR_1976	ENOG4105CQ7	ATP-dependent helicase
TVNIR_1985	ENOG4108UJV	acyl-CoA thioesterase i
TVNIR_1986	ENOG4108I0Y	(ABC) transporter
TVNIR_1988	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
TVNIR_1989	ENOG4105UYK	outer membrane protein a
TVNIR_1993	ENOG4108JJA	ABC, transporter
TVNIR_1994	ENOG4107QZV	Type I secretion membrane fusion protein
TVNIR_2003	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
TVNIR_2007	ENOG4105BZU	Histidine kinase
TVNIR_2008	ENOG41062IR	nudix hydrolase
TVNIR_2009	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
TVNIR_2011	ENOG4105EJ5	oxidoreductase gamma subunit
TVNIR_2012	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
TVNIR_2013	ENOG4105DDK	oxidoreductase, beta subunit
TVNIR_2015	ENOG4105CJ3	phosphate transporter
TVNIR_2021	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
TVNIR_2022	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
TVNIR_2023	ENOG41060IM	Heme exporter protein
TVNIR_2025	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
TVNIR_2028	ENOG4105DA4	cytochrome c-type biogenesis protein
TVNIR_2029	ENOG4107QX9	Thiol disulfide interChange protein
TVNIR_2030	ENOG4105KWW	Biogenesis protein
TVNIR_2033	ENOG4105CUW	cytochrome C-TYPE protein
TVNIR_2034	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
TVNIR_2037	ENOG4105C45	hydrogenase expression formation protein (HypE)
TVNIR_2039	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
TVNIR_2045	ENOG4107RSS	Hydrogenase accessory protein HypB
TVNIR_2048	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
TVNIR_2052	ENOG4108USZ	hydrogenase
TVNIR_2054	ENOG4105E3S	small subunit
TVNIR_2061	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
TVNIR_2062	ENOG4105CGD	Nad-dependent epimerase dehydratase
TVNIR_2067	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
TVNIR_2070	ENOG4105E4C	Lytic transglycosylase catalytic
TVNIR_2080	ENOG4105BZU	Histidine kinase
TVNIR_2081	ENOG4105D44	asparaginase
TVNIR_2089	ENOG4105VUH	addiction module killer protein
TVNIR_2090	ENOG4105YES	addiction module antidote protein
TVNIR_2107	ENOG4105DFP	Integrase
TVNIR_2109	ENOG4108MN8	Membrane
TVNIR_2110	ENOG4105C5I	Dehydrogenase
TVNIR_2111	ENOG4105VRX	Protein slyX homolog
TVNIR_2112	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
TVNIR_2119	ENOG4108VPT	UPF0234 protein
TVNIR_2120	ENOG4105M08	Membrane
TVNIR_2122	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
TVNIR_2124	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
TVNIR_2130	ENOG4105D7D	AAA ATPase
TVNIR_2157	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
TVNIR_2161	ENOG4107SBE	Glycosyl transferase (Group 1
TVNIR_2162	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
TVNIR_2163	ENOG4106WTF	Glycosyl transferase, family 2
TVNIR_2166	ENOG4105M5K	heptosyltransferase
TVNIR_2171	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
TVNIR_2177	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
TVNIR_2180	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
TVNIR_2183	ENOG4105D4P	Coproporphyrinogen iii oxidase
TVNIR_2184	ENOG4105CY0	Metallo-Beta-Lactamase
TVNIR_2187	ENOG4106R49	Methyltransferase
TVNIR_2188	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
TVNIR_2190	ENOG4107S2Z	UPF0761 membrane protein
TVNIR_2193	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
TVNIR_2196	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
TVNIR_2197	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
TVNIR_2198	ENOG4108Z43	UPF0250 protein
TVNIR_2199	ENOG4105F0I	Aminotransferase
TVNIR_2200	ENOG4105DZ1	carboxypeptidase
TVNIR_2201	ENOG4105K6T	rare lipoprotein A
TVNIR_2202	ENOG4105CVE	Lytic murein transglycosylase
TVNIR_2203	ENOG4105CNI	cell division protein FtsW
TVNIR_2204	ENOG4105CJN	penicillin-binding protein
TVNIR_2205	ENOG4105F0N	pyrophosphate phospho-hydrolase
TVNIR_2206	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
TVNIR_2207	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
TVNIR_2208	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
TVNIR_2209	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
TVNIR_2210	ENOG4105CHC	glucokinase (EC 2.7.1.2)
TVNIR_2211	ENOG4105NWN	ApaG protein
TVNIR_2212	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
TVNIR_2214	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
TVNIR_2215	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
TVNIR_2216	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
TVNIR_2217	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
TVNIR_2218	ENOG41082NX	50s ribosomal protein l35
TVNIR_2219	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
TVNIR_2220	ENOG4105C22	threonyL-tRNA synthetase
TVNIR_2221	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
TVNIR_2227	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
TVNIR_2228	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
TVNIR_2234	ENOG4105K3M	)-transporter
TVNIR_2237	ENOG4105CQB	FAD linked oxidase domain protein
TVNIR_2238	ENOG4105EU8	FAD linked oxidase domain protein
TVNIR_2239	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
TVNIR_2240	ENOG4107QP3	malate synthase g
TVNIR_2242	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
TVNIR_2243	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
TVNIR_2247	ENOG4108I9X	Isocitrate lyase
TVNIR_2248	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
TVNIR_2249	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
TVNIR_2250	ENOG4105ECY	inositol monophosphatase
TVNIR_2251	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TVNIR_2252	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
TVNIR_2253	ENOG4105VIE	preprotein translocase, subunit YajC
TVNIR_2254	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
TVNIR_2255	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
TVNIR_2258	ENOG4108I5C	dEAD DEAH box helicase
TVNIR_2260	ENOG4107R3N	Filamentation induced by cAMP protein fic
TVNIR_2275	ENOG4108UK5	Transposase
TVNIR_2276	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
TVNIR_2278	ENOG4105C0D	helicase
TVNIR_2307	ENOG4105CHR	reductase
TVNIR_2308	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
TVNIR_2313	ENOG4107S9F	NmrA family
TVNIR_2323	ENOG4105EKQ	RNA-directed DNA polymerase
TVNIR_2333	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TVNIR_2334	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TVNIR_2336	ENOG4107QVI	Methyltransferase, type 11
TVNIR_2339	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
TVNIR_2340	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
TVNIR_2341	ENOG4105DXN	mazG family
TVNIR_2343	ENOG4105BZG	amino acid carrier protein
TVNIR_2359	ENOG4105C3U	ABC transporter
TVNIR_2360	ENOG4108JQ7	(ABC) transporter
TVNIR_2363	ENOG4105KJM	monovalent cation h antiporter subunit g
TVNIR_2364	ENOG41080TA	Multiple resistance and ph regulation protein f
TVNIR_2365	ENOG4105SC1	monovalent cation H antiporter subunit E
TVNIR_2366	ENOG4108JPZ	Monovalent cation H antiporter subunit D
TVNIR_2367	ENOG4105MKQ	Monovalent cation H antiporter subunit C
TVNIR_2368	ENOG4105HC0	Na H antiporter
TVNIR_2369	ENOG4105D65	subunit l
TVNIR_2370	ENOG4106MWK	domain protein
TVNIR_2372	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
TVNIR_2373	ENOG4105DHP	deoxycytidine triphosphate deaminase
TVNIR_2375	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
TVNIR_2376	ENOG4107QY0	Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) (By similarity)
TVNIR_2378	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
TVNIR_2379	ENOG4105DGN	Electron transport complex
TVNIR_2380	ENOG4108R3D	Electron transport complex
TVNIR_2382	ENOG4105D6A	Electron transport complex
TVNIR_2384	ENOG4105DZB	Electron transport complex
TVNIR_2386	ENOG4105CSM	endonuclease III
TVNIR_2390	ENOG4108XDN	Transcriptional regulator
TVNIR_2392	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
TVNIR_2396	ENOG4105C1J	atp-dependent rna helicase
TVNIR_2398	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TVNIR_2405	ENOG4105EUJ	GTP cyclohydrolase i
TVNIR_2413	ENOG41067HS	methyltransferase
TVNIR_2414	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
TVNIR_2416	ENOG4105BZU	Histidine kinase
TVNIR_2417	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
TVNIR_2419	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
TVNIR_2420	ENOG4108IFG	nitrite reductase, (NAD(P)H)
TVNIR_2421	ENOG4105D7T	ABC transporter
TVNIR_2428	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
TVNIR_2429	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
TVNIR_2434	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TVNIR_2435	ENOG4105CJW	magnesium transporter
TVNIR_2436	ENOG4105CJW	magnesium transporter
TVNIR_2454	ENOG4105N42	UPF0307 protein
TVNIR_2457	ENOG4105N42	UPF0307 protein
TVNIR_2463	ENOG4105BZM	domain protein
TVNIR_2466	ENOG4105BZU	Histidine kinase
TVNIR_2471	ENOG4105WQ5	TonB family
TVNIR_2473	ENOG4108UQY	Iron-storage protein
TVNIR_2475	ENOG4105C4M	(Ubiquinol oxidase) subunit I
TVNIR_2476	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
TVNIR_2478	ENOG4108JJ9	ABC, transporter
TVNIR_2479	ENOG4108JJ8	(ABC) transporter
TVNIR_2481	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
TVNIR_2482	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
TVNIR_2483	ENOG4105C34	Pseudouridine synthase
TVNIR_2484	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TVNIR_2485	ENOG4108YZA	Nitrogen regulatory protein pii
TVNIR_2486	ENOG4105C4K	Nad synthetase
TVNIR_2487	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
TVNIR_2488	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
TVNIR_2493	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
TVNIR_2497	ENOG4105VK0	repeat-containing protein
TVNIR_2508	ENOG4107RBB	ABC transporter, permease
TVNIR_2509	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
TVNIR_2515	ENOG4107TUY	Histidine kinase
TVNIR_2516	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TVNIR_2517	ENOG4108Z03	MAF-like protein
TVNIR_2520	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
TVNIR_2521	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
TVNIR_2524	ENOG4105C8T	Leucyl-tRNA synthetase
TVNIR_2529	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
TVNIR_2537	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TVNIR_2540	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
TVNIR_2541	ENOG4108JU5	Magnesium and cobalt efflux protein
TVNIR_2542	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
TVNIR_2543	ENOG4105C9A	Phoh family
TVNIR_2544	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
TVNIR_2545	ENOG4108UUM	single-stranded DNA-binding protein
TVNIR_2546	ENOG4108MTT	Glutamate-rich protein grpB
TVNIR_2547	ENOG4107RDB	Major Facilitator
TVNIR_2548	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
TVNIR_2549	ENOG4108ZT0	50S ribosomal protein l17
TVNIR_2550	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TVNIR_2551	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
TVNIR_2552	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
TVNIR_2553	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TVNIR_2554	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
TVNIR_2555	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
TVNIR_2556	ENOG4105VPB	50S ribosomal protein L30
TVNIR_2557	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
TVNIR_2558	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
TVNIR_2559	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
TVNIR_2560	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
TVNIR_2561	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
TVNIR_2562	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TVNIR_2563	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
TVNIR_2564	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
TVNIR_2565	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
TVNIR_2567	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
TVNIR_2568	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
TVNIR_2569	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
TVNIR_2570	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
TVNIR_2571	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TVNIR_2572	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
TVNIR_2573	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
TVNIR_2574	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
TVNIR_2575	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
TVNIR_2576	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
TVNIR_2577	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TVNIR_2578	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
TVNIR_2579	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
TVNIR_2580	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TVNIR_2581	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
TVNIR_2582	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
TVNIR_2583	ENOG4108VZM	50s ribosomal protein L10
TVNIR_2584	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
TVNIR_2585	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
TVNIR_2586	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
TVNIR_2587	ENOG4105PM1	preprotein translocase subunit SecE
TVNIR_2588	ENOG4107QHF	type ii secretion system protein e
TVNIR_2591	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
TVNIR_2592	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
TVNIR_2593	ENOG4105M6F	mutator MutT protein
TVNIR_2594	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
TVNIR_2595	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
TVNIR_2596	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
TVNIR_2598	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
TVNIR_2599	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
TVNIR_2600	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
TVNIR_2601	ENOG4105CPF	Cell wall formation (By similarity)
TVNIR_2602	ENOG4105D4A	Cell wall formation (By similarity)
TVNIR_2603	ENOG4105DFU	Cell wall formation (By similarity)
TVNIR_2604	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
TVNIR_2605	ENOG4105CNI	cell division protein FtsW
TVNIR_2606	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
TVNIR_2607	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
TVNIR_2608	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
TVNIR_2609	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
TVNIR_2610	ENOG4105CJN	penicillin-binding protein
TVNIR_2611	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
TVNIR_2612	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
TVNIR_2613	ENOG4108V6E	Cell division protein mraZ
TVNIR_2614	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
TVNIR_2616	ENOG41082RQ	UPF0102 protein
TVNIR_2617	ENOG4105KB2	stringent starvation protein b
TVNIR_2618	ENOG4105CQB	FAD linked oxidase domain protein
TVNIR_2619	ENOG4107MKT	Stringent starvation protein a
TVNIR_2620	ENOG4105EIX	cytochrome c1
TVNIR_2621	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
TVNIR_2622	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
TVNIR_2623	ENOG4107QNR	UPF0135 protein
TVNIR_2624	ENOG4105C0H	protease
TVNIR_2625	ENOG4105CIH	Imidazole acetol-phosphate transaminase
TVNIR_2626	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
TVNIR_2627	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
TVNIR_2629	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
TVNIR_2632	ENOG4107PE3	Mammalian cell entry related domain protein
TVNIR_2633	ENOG4105CY3	ABC transporter, permease
TVNIR_2634	ENOG4105DHJ	ABC, transporter
TVNIR_2637	ENOG4105C2X	Arabinose 5-phosphate isomerase
TVNIR_2638	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
TVNIR_2641	ENOG4108IUZ	ABC transporter
TVNIR_2642	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TVNIR_2643	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
TVNIR_2644	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
TVNIR_2645	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
TVNIR_2646	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
TVNIR_2648	ENOG41080Z8	PHOSPHOCARRIER protein
TVNIR_2650	ENOG41080RH	Thioredoxin
TVNIR_2652	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
TVNIR_2653	ENOG4105DFU	Cell wall formation (By similarity)
TVNIR_2655	ENOG410903C	(LipO)protein
TVNIR_2656	ENOG4105CDH	Citrulline--aspartate ligase
TVNIR_2658	ENOG4105E0A	ABC, transporter
TVNIR_2659	ENOG4105EHG	Permease protein
TVNIR_2664	ENOG4107QN2	dihydrolipoyl dehydrogenase
TVNIR_2665	ENOG4107QSN	dihydrolipoamide acetyltransferase
TVNIR_2666	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
TVNIR_2669	ENOG4105M2J	Glutaredoxin
TVNIR_2670	ENOG4105C3G	gtp-binding protein
TVNIR_2671	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
TVNIR_2672	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
TVNIR_2673	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
TVNIR_2674	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
TVNIR_2676	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
TVNIR_2677	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
TVNIR_2678	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
TVNIR_2681	ENOG4105D06	uba thif-type nad fad binding protein
TVNIR_2682	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
TVNIR_2683	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TVNIR_2684	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
TVNIR_2686	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
TVNIR_2687	ENOG4105DFF	Rod shape-determining protein mreb
TVNIR_2688	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
TVNIR_2689	ENOG4105VQ7	Rod shape-determining protein MreD
TVNIR_2690	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
TVNIR_2693	ENOG4105XA0	heptosyltransferase ii
TVNIR_2694	ENOG4105DKP	glycosyl transferase, family 9
TVNIR_2695	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
TVNIR_2696	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
TVNIR_2697	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
TVNIR_2698	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
TVNIR_2700	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
TVNIR_2701	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
TVNIR_2709	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
TVNIR_2710	ENOG4107YB6	acetyltransferase, (GNAT) family
TVNIR_2712	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
TVNIR_2713	ENOG4105BZU	Histidine kinase
TVNIR_2713	ENOG4105BZU	Histidine kinase
TVNIR_2714	ENOG4105WH1	Two component transcriptional regulator luxr family
TVNIR_2716	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
TVNIR_2720	ENOG4105D3R	alkyl hydroperoxide reductase
TVNIR_2722	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
TVNIR_2723	ENOG4108JDX	DNA polymerase iii, epsilon subunit
TVNIR_2724	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
TVNIR_2729	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
TVNIR_2730	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
TVNIR_2736	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
TVNIR_2739	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
TVNIR_2741	ENOG4105CA0	peroxidase
TVNIR_2743	ENOG4105SG9	biopolymer transport protein, ExbD
TVNIR_2744	ENOG4105E02	MotA TolQ exbB proton channel
TVNIR_2745	ENOG4105WQ5	TonB family
TVNIR_2748	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
TVNIR_2750	ENOG4107S7U	Sulfide dehydrogenase
TVNIR_2752	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TVNIR_2753	ENOG4105BZU	Histidine kinase
TVNIR_2756	ENOG4105C19	ABC transporter
TVNIR_2757	ENOG4105D60	lipoprotein releasing system transmembrane protein
TVNIR_2758	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TVNIR_2759	ENOG4107RBB	ABC transporter, permease
TVNIR_2764	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
TVNIR_2765	ENOG41081FY	multiple antibiotic resistance (MarC)-related
TVNIR_2769	ENOG4105K70	DNA-binding protein
TVNIR_2772	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
TVNIR_2773	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
TVNIR_2774	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
TVNIR_2775	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
TVNIR_2776	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
TVNIR_2777	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
TVNIR_2778	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
TVNIR_2779	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
TVNIR_2780	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
TVNIR_2781	ENOG4105K8N	protein family UPF0079, ATPase
TVNIR_2782	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
TVNIR_2783	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
TVNIR_2784	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TVNIR_2785	ENOG4105K63	Thioredoxin
TVNIR_2787	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
TVNIR_2788	ENOG4107QX8	SPFH domain, Band 7 family protein
TVNIR_2791	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
TVNIR_2792	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
TVNIR_2798	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
TVNIR_2801	ENOG4108YZN	class I peptide chain release factor
TVNIR_2804	ENOG4108UJV	acyl-CoA thioesterase i
TVNIR_2805	ENOG4105C94	Transporter
TVNIR_2808	ENOG4107QP8	phosphohexose isomerase
TVNIR_2809	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
TVNIR_2810	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
TVNIR_2811	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
TVNIR_2812	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
TVNIR_2813	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
TVNIR_2815	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TVNIR_2816	ENOG4105DJ0	Poly(A) Polymerase
TVNIR_2818	ENOG4105VEJ	Heat shock protein
TVNIR_2819	ENOG4108TGY	Glutathione S-transferase
TVNIR_2824	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
TVNIR_2829	ENOG4105C0D	helicase
TVNIR_2837	ENOG4105F5W	AtP-binding protein
TVNIR_2845	ENOG4105VXN	addiction module toxin, RelE StbE family
TVNIR_2846	ENOG4105MP0	transposase
TVNIR_2848	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
TVNIR_2856	ENOG41084A1	Protein CrcB homolog
TVNIR_2857	ENOG41084I6	Protein CrcB homolog
TVNIR_2858	ENOG4105KJJ	Uncharacterized ACR, COG1993
TVNIR_2872	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
TVNIR_2873	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
TVNIR_2876	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
TVNIR_2877	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
TVNIR_2878	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
TVNIR_2882	ENOG4105WKW	Pfam:DUF1458
TVNIR_2885	ENOG4105C5R	Aminotransferase
TVNIR_2888	ENOG4108SHN	Glycosyl transferase, family 2
TVNIR_2889	ENOG4107QK7	reductase
TVNIR_2891	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TVNIR_2893	ENOG4108T9Q	UPF0278 protein
TVNIR_2894	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
TVNIR_2898	ENOG4105C01	Dihydroxy-acid dehydratase
TVNIR_2901	ENOG4105EWT	decarboxylase family
TVNIR_2915	ENOG4105CD5	CoA-binding domain protein
TVNIR_2918	ENOG4105KAV	tspo and mbr like protein
TVNIR_2920	ENOG4105VXP	Protein of unknown function DUF86
TVNIR_2925	ENOG41061WM	D-Alanyl-D-Alanine
TVNIR_2926	ENOG4108RSN	SNARE associated Golgi
TVNIR_2927	ENOG4105D1H	recombination factor protein RarA
TVNIR_2929	ENOG4105CNU	cell division protein FtsK
TVNIR_2930	ENOG4105C3M	thioredoxin reductase
TVNIR_2932	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
TVNIR_2934	ENOG4105EMU	Dehydrogenase
TVNIR_2937	ENOG4105C0B	DNA polymerase III (alpha subunit)
TVNIR_2938	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
TVNIR_2947	ENOG4105BZS	acriflavin resistance protein
TVNIR_2952	ENOG4105D6E	homoserine dehydrogenase
TVNIR_2953	ENOG4105CHM	Aminotransferase
TVNIR_2954	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TVNIR_2956	ENOG4108K5P	(LipO)protein
TVNIR_2957	ENOG4108UM1	dedA family
TVNIR_2958	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
TVNIR_2959	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
TVNIR_2962	ENOG4105BZU	Histidine kinase
TVNIR_2963	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
TVNIR_2964	ENOG41072GX	Peptidase M22 Glycoprotease
TVNIR_2965	ENOG4105DVT	helicase
TVNIR_2967	ENOG4105BZ4	penicillin-binding protein
TVNIR_2970	ENOG4105K4H	Nlp p60 protein
TVNIR_2972	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
TVNIR_2976	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
TVNIR_2978	ENOG4105DUM	transcriptional regulator, lysR family
TVNIR_2983	ENOG4105KNY	Microcompartments protein
TVNIR_2984	ENOG4105KNY	Microcompartments protein
TVNIR_2985	ENOG4105KNY	Microcompartments protein
TVNIR_2991	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
TVNIR_2992	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
TVNIR_2994	ENOG4105NXH	GreA GreB family elongation factor
TVNIR_2996	ENOG4105BZU	Histidine kinase
TVNIR_3000	ENOG4108VWS	Yaeq family
TVNIR_3002	ENOG4105DZ2	Transcriptional regulator
TVNIR_3003	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
TVNIR_3008	ENOG4105MQ2	17 kDa surface antigen
TVNIR_3009	ENOG4106YVY	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) (By similarity)
TVNIR_3011	ENOG4105N7H	Cytochrome
TVNIR_3017	ENOG4105CUC	YeeE YedE family protein
TVNIR_3018	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
TVNIR_3019	ENOG4107SGF	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
TVNIR_3023	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
TVNIR_3027	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
TVNIR_3031	ENOG4105CYN	Serine protein kinase
TVNIR_3032	ENOG4106AKX	UPF0229 protein
TVNIR_3033	ENOG4105ED1	spovr family
TVNIR_3039	ENOG4105K6T	rare lipoprotein A
TVNIR_3043	ENOG4108V1T	peptidylprolyl cis-trans isomerase
TVNIR_3049	ENOG4105CVE	Lytic murein transglycosylase
TVNIR_3055	ENOG4106AXJ	AraC family transcriptional regulator
TVNIR_3058	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
TVNIR_3060	ENOG4105BZU	Histidine kinase
TVNIR_3064	ENOG4107VAM	peptidase, m28
TVNIR_3066	ENOG4105C1G	acyl-Coa dehydrogenase
TVNIR_3067	ENOG4108K2B	transcriptional regulator
TVNIR_3069	ENOG4107TPS	domain protein
TVNIR_3070	ENOG4107R1Y	fructose-bisphosphate aldolase
TVNIR_3072	ENOG4105C01	Dihydroxy-acid dehydratase
TVNIR_3078	ENOG41067SE	Tetr family transcriptional regulator
TVNIR_3083	ENOG4108UNV	SUF system FeS assembly protein, NifU family
TVNIR_3084	ENOG4105C9B	Cysteine desulfurase
TVNIR_3085	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TVNIR_3086	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TVNIR_3088	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
TVNIR_3089	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
TVNIR_3090	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
TVNIR_3091	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
TVNIR_3093	ENOG4105BZU	Histidine kinase
TVNIR_3094	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TVNIR_3097	ENOG4107QN1	sodium solute
TVNIR_3100	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
TVNIR_3104	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
TVNIR_3106	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
TVNIR_3107	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
TVNIR_3108	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
TVNIR_3109	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
TVNIR_3110	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
TVNIR_3111	ENOG4105CHV	Transcription elongation factor NusA
TVNIR_3113	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TVNIR_3114	ENOG4105C8S	subunit m
TVNIR_3116	ENOG41080FQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TVNIR_3117	ENOG4105DF2	NADH dehydrogenase subunit j
TVNIR_3118	ENOG41081XG	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TVNIR_3119	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
TVNIR_3121	ENOG4107QIZ	NADH dehydrogenase
TVNIR_3123	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TVNIR_3124	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TVNIR_3125	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
TVNIR_3126	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
TVNIR_3127	ENOG4107EJC	Preprotein translocase subunit SecG
TVNIR_3128	ENOG4105CP7	Triose-phosphate isomerase
TVNIR_3129	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
TVNIR_3130	ENOG4105EEI	dihydropteroate synthase
TVNIR_3131	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
TVNIR_3132	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
TVNIR_3133	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
TVNIR_3134	ENOG4105HBR	Rna-binding protein
TVNIR_3135	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
TVNIR_3136	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
TVNIR_3138	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
TVNIR_3140	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
TVNIR_3142	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
TVNIR_3143	ENOG4105DJ4	phosphatidylserine decarboxylase
TVNIR_3145	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
TVNIR_3146	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
TVNIR_3147	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
TVNIR_3149	ENOG4105BZU	Histidine kinase
TVNIR_3150	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
TVNIR_3151	ENOG4105CFG	Acts as a chaperone (By similarity)
TVNIR_3152	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TVNIR_3153	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
TVNIR_3154	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
TVNIR_3155	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
TVNIR_3156	ENOG41090R7	Ferric uptake
TVNIR_3157	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
TVNIR_3158	ENOG4105VDB	UPF0125 protein
TVNIR_3159	ENOG4108Z1B	Cyclase dehydrase
TVNIR_3160	ENOG4105C8J	)-transporter
TVNIR_3161	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
TVNIR_3162	ENOG4105CA0	peroxidase
TVNIR_3165	ENOG4105C5H	ABC transporter
TVNIR_3169	ENOG4105CKI	cobalamin synthesis protein
TVNIR_3173	ENOG4105C0D	helicase
TVNIR_3178	ENOG4108RAV	Conserved protein
TVNIR_3180	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
TVNIR_3182	ENOG4105ED9	Protein of unknown function (DUF455)
TVNIR_3183	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
TVNIR_3184	ENOG4105C28	cystathionine
TVNIR_3185	ENOG4105BZU	Histidine kinase
TVNIR_3187	ENOG4108UJD	30S ribosomal protein S9
TVNIR_3188	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
TVNIR_3190	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TVNIR_3191	ENOG4105BZU	Histidine kinase
TVNIR_3192	ENOG4105C5X	domain protein
TVNIR_3193	ENOG4105D0M	Protease HtpX homolog
TVNIR_3194	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TVNIR_3195	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
TVNIR_3202	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
TVNIR_3203	ENOG4105MYG	DNA polymerase iii, chi subunit
TVNIR_3204	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
TVNIR_3205	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
TVNIR_3208	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
TVNIR_3210	ENOG4105C9U	ATP-dependent DNA helicase RecQ
TVNIR_3211	ENOG4108JJ7	ABC transporter
TVNIR_3212	ENOG4105N1F	Hnh endonuclease
TVNIR_3215	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
TVNIR_3218	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
TVNIR_3219	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
TVNIR_3220	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
TVNIR_3221	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
TVNIR_3223	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
TVNIR_3224	ENOG4108ZP8	Acetolactate synthase small subunit
TVNIR_3225	ENOG4105C7K	acetolactate synthase
TVNIR_3231	ENOG4105DF9	Lipoate-protein, ligase
TVNIR_3240	ENOG4107ENK	receptor
TVNIR_3241	ENOG4105PHD	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
TVNIR_3243	ENOG4105RQ5	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
TVNIR_3244	ENOG41086B8	CoB-CoM heterodisulfide reductase
TVNIR_3247	ENOG4105EWK	phytoene
TVNIR_3250	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
TVNIR_3251	ENOG41082J7	Rhodanese domain protein
TVNIR_3253	ENOG4105ERG	peptidase m48, ste24p
TVNIR_3254	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
TVNIR_3255	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
TVNIR_3256	ENOG4105CDU	Replicative dna helicase
TVNIR_3257	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
TVNIR_3259	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
TVNIR_3260	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
TVNIR_3261	ENOG4105C2N	RNA methyltransferase TrmH family group 3
TVNIR_3262	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
TVNIR_3263	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
TVNIR_3264	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
TVNIR_3266	ENOG4105EPW	hflc protein
TVNIR_3267	ENOG4107QJR	hflk protein
TVNIR_3269	ENOG4105CHF	Glutathione S-transferase
TVNIR_3275	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
TVNIR_3286	ENOG4108RJ7	Catalyzes the hydrolysis of nucleoside triphosphates, with a preference for pyrimidine deoxynucleoside triphosphates (dUTP, dTTP and dCTP) (By similarity)
TVNIR_3287	ENOG4105C4R	Atp-dependent dna helicase
TVNIR_3310	ENOG4105YAJ	CopG Arc MetJ
TVNIR_3316	ENOG4105VT3	DNA binding domain protein, excisionase family
TVNIR_3317	ENOG4105K5B	UPF0225 protein
TVNIR_3319	ENOG4105C0D	helicase
TVNIR_3321	ENOG4105VT3	DNA binding domain protein, excisionase family
TVNIR_3329	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
TVNIR_3340	ENOG4105CR4	methylisocitrate lyase
TVNIR_3341	ENOG4105BZN	citrate synthase
TVNIR_3342	ENOG4105DXD	2-methylcitrate dehydratase
TVNIR_3343	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
TVNIR_3344	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
TVNIR_3348	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
TVNIR_3355	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
TVNIR_3360	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
TVNIR_3364	ENOG4105E0X	reductase
TVNIR_3365	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
TVNIR_3366	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
TVNIR_3368	ENOG4105KCK	Peptidoglycan-associated lipoprotein
TVNIR_3369	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
TVNIR_3371	ENOG4105M8F	Biopolymer transport protein exbD tolR
TVNIR_3372	ENOG4105E02	MotA TolQ exbB proton channel
TVNIR_3373	ENOG4107YD3	Thioesterase
TVNIR_3374	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
TVNIR_3375	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
TVNIR_3376	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
TVNIR_3377	ENOG4105CDY	transcriptional regulatory protein
TVNIR_3379	ENOG4105C9M	aspartyl-trna synthetase
TVNIR_3385	ENOG4105E1F	short-chain dehydrogenase reductase
TVNIR_3386	ENOG4108JIC	nucleoside recognition domain protein
TVNIR_3387	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
TVNIR_3392	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
TVNIR_3393	ENOG4105K89	arsenate reductase
TVNIR_3394	ENOG4105CS1	NAD(P)H quinone oxidoreductase
TVNIR_3396	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
TVNIR_3397	ENOG4108UKJ	Cdp-alcohol phosphatidyltransferase
TVNIR_3399	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
TVNIR_3400	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
TVNIR_3402	ENOG4107QN2	dihydrolipoyl dehydrogenase
TVNIR_3403	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
TVNIR_3405	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
TVNIR_3408	ENOG4105C03	ribonuclease
TVNIR_3412	ENOG4105DUM	transcriptional regulator, lysR family
TVNIR_3415	ENOG4105ERU	peptidase
TVNIR_3416	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
TVNIR_3417	ENOG4105D6S	protein involved in catabolism of external DNA
TVNIR_3418	ENOG4108XRS	Monoheme cytochrome SoxX (Sulfur oxidation)
TVNIR_3421	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
TVNIR_3422	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
TVNIR_3423	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
TVNIR_3424	ENOG4105K5M	30s ribosomal protein S16
TVNIR_3425	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TVNIR_3426	ENOG4106KVJ	cytochrome C assembly protein
TVNIR_3427	ENOG4108JU6	CBS domain protein
TVNIR_3428	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
TVNIR_3432	ENOG4108RAC	Rubrerythrin
TVNIR_3433	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
TVNIR_3434	ENOG4105CTB	Polyprenyl synthetase
TVNIR_3435	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
TVNIR_3436	ENOG4108IAB	Phoh family
TVNIR_3437	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
TVNIR_3439	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
TVNIR_3440	ENOG4105GJM	(LipO)protein
TVNIR_3442	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
TVNIR_3443	ENOG4105DR5	peptidase
TVNIR_3444	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
TVNIR_3445	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
TVNIR_3446	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
TVNIR_3448	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
TVNIR_3449	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
TVNIR_3452	ENOG4105DWF	phosphomethylpyrimidine kinase
TVNIR_3453	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
TVNIR_3454	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
TVNIR_3455	ENOG4105HF0	Membrane
TVNIR_3456	ENOG4105CD8	aminopeptidase N
TVNIR_3458	ENOG4105F8V	Hydrolase, tatD family
TVNIR_3459	ENOG4105M85	Bola protein
TVNIR_3465	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
TVNIR_3467	ENOG4105TNG	K13735 adhesin invasin
TVNIR_3474	ENOG4108JQC	penicillin-binding protein 1A
TVNIR_3476	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
TVNIR_3478	ENOG4105VCC	30S ribosomal protein S21
TVNIR_3479	ENOG4105D49	3-dehydroquinate synthase
TVNIR_3480	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
TVNIR_3482	ENOG4105E0A	ABC, transporter
TVNIR_3483	ENOG4105EHG	Permease protein
TVNIR_3484	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
TVNIR_3485	ENOG4108374	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
TVNIR_3488	ENOG4108YZT	Adenosylcobinamide kinase
TVNIR_3490	ENOG4105EFT	decarboxylase
TVNIR_3491	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
TVNIR_3492	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
TVNIR_3494	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
TVNIR_3495	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
TVNIR_3496	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
TVNIR_3512	ENOG4105EKQ	RNA-directed DNA polymerase
TVNIR_3515	ENOG4105NAE	bifunctional deaminase-reductase domain protein
TVNIR_3516	ENOG4105CHP	RNA polymerase
TVNIR_3518	ENOG4105GRZ	Ycii-related protein
TVNIR_3539	ENOG4105E0X	reductase
TVNIR_3540	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
TVNIR_3543	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
TVNIR_3544	ENOG4105CKK	Glycosyl transferase, family 2
TVNIR_3547	ENOG4105CEV	competence damage-inducible protein
TVNIR_3548	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
TVNIR_3550	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
TVNIR_3551	ENOG4105W8H	transhydrogenase (subunit alpha
TVNIR_3552	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
TVNIR_3553	ENOG4105C25	Primosomal protein n'
TVNIR_3555	ENOG4105C75	arginyL-tRNA synthetase
TVNIR_3557	ENOG4105CQ7	ATP-dependent helicase
TVNIR_3559	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
TVNIR_3561	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
TVNIR_3563	ENOG4105MYN	Zinc uptake regulation protein
TVNIR_3565	ENOG4105CHB	tonB-dependent Receptor
TVNIR_3568	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
TVNIR_3570	ENOG4107QKV	phosphomannomutase
TVNIR_3574	ENOG4105BZU	Histidine kinase
TVNIR_3575	ENOG4107W7X	Aldolase
TVNIR_3576	ENOG4105E7A	Glutamine amidotransferase
TVNIR_3578	ENOG4105DAN	ATP-dependent protease
TVNIR_3580	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
TVNIR_3582	ENOG41080HT	Transcriptional regulator, arsr family
TVNIR_3588	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
TVNIR_3589	ENOG4105CEN	a g-specific adenine glycosylase
TVNIR_3592	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TVNIR_3593	ENOG4105M00	molybdopterin converting factor, subunit 1
TVNIR_3594	ENOG4108ZAF	Molybdopterin
TVNIR_3595	ENOG4105C0H	protease
TVNIR_3597	ENOG4105VN1	Heat shock protein
TVNIR_3599	ENOG4105DSJ	YicC domain protein
TVNIR_3600	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
TVNIR_3601	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
TVNIR_3602	ENOG4105CSA	Coproporphyrinogen iii oxidase
TVNIR_3606	ENOG4105K63	Thioredoxin
TVNIR_3609	ENOG4108YZY	peptidylprolyl cis-trans isomerase
TVNIR_3614	ENOG4107RIQ	Sulfate adenylate transferase
TVNIR_3618	ENOG4105DB1	molybdopterin oxidoreductase
TVNIR_3619	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
TVNIR_3620	ENOG4108KDI	dmso reductase anchor subunit
TVNIR_3622	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
TVNIR_3623	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
TVNIR_3624	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
TVNIR_3627	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
TVNIR_3628	ENOG4108WUH	Transcriptional regulator, TetR family
TVNIR_3629	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
TVNIR_3630	ENOG4105DFG	type I secretion outer membrane protein
TVNIR_3635	ENOG4105C5H	ABC transporter
TVNIR_3636	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
TVNIR_3637	ENOG4105VEQ	Cold shock protein
TVNIR_3638	ENOG4105C5F	glutamine synthetase
TVNIR_3640	ENOG41076HS	cation diffusion facilitator family transporter
TVNIR_3642	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
TVNIR_3643	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
TVNIR_3645	ENOG4105CUZ	uba thif-type nad fad binding protein
TVNIR_3646	ENOG4105F8V	Hydrolase, tatD family
TVNIR_3649	ENOG4105CPC	Aldo Keto reductase
TVNIR_3652	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
TVNIR_3655	ENOG4108YV4	Universal stress protein
TVNIR_3656	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
TVNIR_3657	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
TVNIR_3670	ENOG4105EUB	pirin domain protein
TVNIR_3673	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
TVNIR_3677	ENOG4105X54	addiction module antidote protein
TVNIR_3685	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
TVNIR_3694	ENOG4105BZU	Histidine kinase
TVNIR_3698	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
TVNIR_3699	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
TVNIR_3700	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
TVNIR_3701	ENOG4105KME	endoribonuclease L-psp
TVNIR_3702	ENOG4105CB5	ATP-dependent DNA helicase recG
TVNIR_3704	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
TVNIR_3705	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
TVNIR_3706	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
TVNIR_3707	ENOG4107QJE	Chromosome Partitioning Protein
TVNIR_3708	ENOG4105FA0	parb-like partition protein
TVNIR_3710	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
TVNIR_3711	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
TVNIR_3712	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
TVNIR_3713	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
TVNIR_3714	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
TVNIR_3715	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
TVNIR_3716	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
TVNIR_3717	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TVNIR_3718	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
TVNIR_3719	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
TVNIR_3721	ENOG4108UUC	Protein of unknown function DUF99
TVNIR_3722	ENOG4105C0H	protease
TVNIR_3724	ENOG4106N16	had-superfamily hydrolase, subfamily iib
TVNIR_3725	ENOG4107S0N	DJ-1 family
TVNIR_3726	ENOG4105CN1	protease
TVNIR_3727	ENOG41063SB	peptidase
TVNIR_3728	ENOG41080HT	Transcriptional regulator, arsr family
TVNIR_3729	ENOG4107YZP	Rhodanese domain protein
TVNIR_3730	ENOG4105VW4	glutaredoxin 3
TVNIR_3732	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
TVNIR_3733	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
TVNIR_3734	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
TVNIR_3735	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
TVNIR_3736	ENOG4105CUX	Signal transduction histidine kinase
TVNIR_3740	ENOG4105C2M	dna polymerase I
TVNIR_3742	ENOG4108ZX6	Electron transport protein SCO1 SenC
TVNIR_3744	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
TVNIR_3745	ENOG4106RE7	Cytochrome
TVNIR_3746	ENOG4108Z33	Thiol disulfide Interchange Protein
TVNIR_3749	ENOG4105CAQ	asparagine synthetase
TVNIR_3750	ENOG4105CXT	aspartate transcarbamylase
TVNIR_3751	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
TVNIR_3754	ENOG41067TZ	transcriptional regulator, MarR family
TVNIR_3756	ENOG4105C94	Transporter
TVNIR_3759	ENOG4105CGK	Exodeoxyribonuclease III
TVNIR_3760	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
TVNIR_3762	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
TVNIR_3766	ENOG4105C5I	Dehydrogenase
TVNIR_3767	ENOG4105C1J	atp-dependent rna helicase
TVNIR_3769	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
TVNIR_3771	ENOG4105CTQ	phosphohexokinase
TVNIR_3774	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
TVNIR_3775	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
TVNIR_3776	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
TVNIR_3783	ENOG4105C7S	Dehydrogenase
TVNIR_3784	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
TVNIR_3785	ENOG4105C4R	Atp-dependent dna helicase
TVNIR_3790	ENOG4107S7U	Sulfide dehydrogenase
TVNIR_3796	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
TVNIR_3797	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TVNIR_3798	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
TVNIR_3799	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
TVNIR_3800	ENOG4105K4G	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
TVNIR_3807	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
TVNIR_3808	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
TVNIR_3809	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
TVNIR_3810	ENOG4105VG0	50S ribosomal protein l34
TVNIR_3811	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
TVNIR_3812	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
TVNIR_3813	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
TVNIR_3816	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
TVNIR_3817	ENOG4108V0P	LemA family
TVNIR_3819	ENOG4105DGW	oligopeptidase A
TVNIR_3820	ENOG4105CGK	Exodeoxyribonuclease III
TVNIR_3823	ENOG4108TEB	UPF0114 protein
TVNIR_3824	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
TVNIR_3827	ENOG4108EX3	reductase
TVNIR_3829	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
TVNIR_3830	ENOG4105CH7	arginosuccinase
TVNIR_3836	ENOG4108RTD	type II secretion system protein K
TVNIR_3837	ENOG4108WWZ	General secretion pathway protein J
TVNIR_3838	ENOG4105X5Z	General secretion pathway protein I
TVNIR_3839	ENOG4105VWV	general secretion pathway protein h
TVNIR_3840	ENOG4108VAU	general secretion pathway protein G
TVNIR_3841	ENOG4105D7Q	type ii secretion system
TVNIR_3843	ENOG4107QHF	type ii secretion system protein e
TVNIR_3844	ENOG4105GVR	general secretion pathway protein D
TVNIR_3846	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
TVNIR_3847	ENOG4105WH1	Two component transcriptional regulator luxr family
TVNIR_3849	ENOG4108IAJ	Nad-dependent epimerase dehydratase