THITH_13240 6dfa59c44e10bb03052b365322ddc141 430 Pfam PF03150 Di-haem cytochrome c peroxidase 100 255 1.5E-36 T 13-10-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 THITH_13240 6dfa59c44e10bb03052b365322ddc141 430 SUPERFAMILY SSF46626 83 242 9.07E-38 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_13240 6dfa59c44e10bb03052b365322ddc141 430 Gene3D G3DSA:1.10.760.10 242 412 9.0E-81 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_13240 6dfa59c44e10bb03052b365322ddc141 430 TIGRFAM TIGR04039 MXAN_0977_Heme2: di-heme enzyme, MXAN_0977 family 92 426 8.3E-153 T 13-10-2018 IPR023929 Di-heme enzyme, MXAN0977 THITH_13240 6dfa59c44e10bb03052b365322ddc141 430 SUPERFAMILY SSF46626 243 417 1.47E-32 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_13240 6dfa59c44e10bb03052b365322ddc141 430 Gene3D G3DSA:1.10.760.10 92 241 9.0E-81 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_13240 6dfa59c44e10bb03052b365322ddc141 430 PIRSF PIRSF000294 52 427 1.4E-64 T 13-10-2018 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 THITH_11625 13ec51714cfbae0dfa698d8b21be7473 140 Pfam PF01029 NusB family 1 120 5.9E-29 T 13-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 THITH_11625 13ec51714cfbae0dfa698d8b21be7473 140 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 5 123 17.826 T 13-10-2018 IPR011605 NusB antitermination factor GO:0006353 THITH_11625 13ec51714cfbae0dfa698d8b21be7473 140 SUPERFAMILY SSF48013 1 124 5.49E-36 T 13-10-2018 IPR035926 NusB-like superfamily THITH_11625 13ec51714cfbae0dfa698d8b21be7473 140 Gene3D G3DSA:1.10.940.10 1 127 1.3E-39 T 13-10-2018 IPR035926 NusB-like superfamily THITH_11625 13ec51714cfbae0dfa698d8b21be7473 140 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 1 121 4.7E-38 T 13-10-2018 IPR011605 NusB antitermination factor GO:0006353 THITH_09435 850bef080eaaef0bf2e12d1e58a7fbd4 587 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 6 587 1.2E-262 T 13-10-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_09435 850bef080eaaef0bf2e12d1e58a7fbd4 587 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 367 389 6.5E-5 T 13-10-2018 THITH_09435 850bef080eaaef0bf2e12d1e58a7fbd4 587 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 6.5E-5 T 13-10-2018 THITH_09435 850bef080eaaef0bf2e12d1e58a7fbd4 587 Gene3D G3DSA:3.90.700.10 246 349 1.6E-163 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_09435 850bef080eaaef0bf2e12d1e58a7fbd4 587 Gene3D G3DSA:1.20.58.100 432 546 1.1E-34 T 13-10-2018 THITH_09435 850bef080eaaef0bf2e12d1e58a7fbd4 587 SUPERFAMILY SSF51905 5 439 1.12E-78 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_09435 850bef080eaaef0bf2e12d1e58a7fbd4 587 Pfam PF02910 Fumarate reductase flavoprotein C-term 459 587 4.5E-38 T 13-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_09435 850bef080eaaef0bf2e12d1e58a7fbd4 587 SUPERFAMILY SSF56425 236 354 2.09E-42 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_09435 850bef080eaaef0bf2e12d1e58a7fbd4 587 Gene3D G3DSA:4.10.80.40 547 587 6.7E-9 T 13-10-2018 THITH_09435 850bef080eaaef0bf2e12d1e58a7fbd4 587 PIRSF PIRSF000171 1 568 4.0E-51 T 13-10-2018 THITH_09435 850bef080eaaef0bf2e12d1e58a7fbd4 587 Pfam PF00890 FAD binding domain 9 404 1.8E-113 T 13-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_09435 850bef080eaaef0bf2e12d1e58a7fbd4 587 SUPERFAMILY SSF46977 451 587 7.72E-48 T 13-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_09435 850bef080eaaef0bf2e12d1e58a7fbd4 587 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 43 52 - T 13-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_09435 850bef080eaaef0bf2e12d1e58a7fbd4 587 Gene3D G3DSA:3.50.50.60 9 415 1.6E-163 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_09435 850bef080eaaef0bf2e12d1e58a7fbd4 587 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 9 587 3.0E-231 T 13-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_16000 51cd99c0727b10ec1b00d0f25ae49682 303 SUPERFAMILY SSF74653 194 297 4.58E-18 T 13-10-2018 THITH_16000 51cd99c0727b10ec1b00d0f25ae49682 303 Gene3D G3DSA:3.30.1150.10 121 296 7.2E-22 T 13-10-2018 THITH_16000 51cd99c0727b10ec1b00d0f25ae49682 303 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 216 280 2.3E-17 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 THITH_16000 51cd99c0727b10ec1b00d0f25ae49682 303 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 218 295 1.7E-16 T 13-10-2018 IPR006260 TonB/TolA, C-terminal THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 709 723 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1054 0.0 T 13-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 428 547 1.6E-39 T 13-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 Gene3D G3DSA:3.30.470.20 665 935 3.4E-119 T 13-10-2018 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 838 845 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 3.7E-73 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 673 874 1.0E-33 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 Pfam PF02142 MGS-like domain 958 1042 5.8E-21 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 SUPERFAMILY SSF52440 556 675 1.41E-49 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 Gene3D G3DSA:3.40.50.1380 936 1072 5.0E-38 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 Gene3D G3DSA:3.30.470.20 119 403 1.0E-128 T 13-10-2018 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 Gene3D G3DSA:3.40.50.20 1 116 2.1E-49 T 13-10-2018 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 SMART SM00851 956 1042 4.0E-34 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 SUPERFAMILY SSF56059 128 401 1.5E-109 T 13-10-2018 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1063 13.27 T 13-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 Gene3D G3DSA:3.40.50.20 554 662 1.9E-49 T 13-10-2018 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 SMART SM01096 424 547 2.2E-70 T 13-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 2.7E-66 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 2.7E-66 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 2.7E-66 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 2.7E-66 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 2.7E-66 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 380 398 2.7E-66 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 2.7E-66 T 13-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1068 13.659 T 13-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 Gene3D G3DSA:1.10.1030.10 404 553 1.0E-48 T 13-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 SUPERFAMILY SSF48108 396 553 1.1E-50 T 13-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 SUPERFAMILY SSF52440 1 127 6.33E-49 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 SUPERFAMILY SSF52335 935 1070 6.8E-39 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THITH_13040 2e6b9694b2b886741cd0fd54c914d787 1079 SUPERFAMILY SSF56059 673 933 1.66E-103 T 13-10-2018 THITH_16700 34e60ac2390764997a86b09de05eed0c 672 Pfam PF00326 Prolyl oligopeptidase family 433 647 1.6E-45 T 13-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 THITH_16700 34e60ac2390764997a86b09de05eed0c 672 SUPERFAMILY SSF82171 38 373 3.53E-18 T 13-10-2018 THITH_16700 34e60ac2390764997a86b09de05eed0c 672 Pfam PF07676 WD40-like Beta Propeller Repeat 45 70 0.17 T 13-10-2018 IPR011659 WD40-like Beta Propeller THITH_16700 34e60ac2390764997a86b09de05eed0c 672 Gene3D G3DSA:2.120.10.30 24 219 1.2E-11 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like THITH_16700 34e60ac2390764997a86b09de05eed0c 672 SUPERFAMILY SSF53474 386 646 2.01E-68 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_16700 34e60ac2390764997a86b09de05eed0c 672 Gene3D G3DSA:3.40.50.1820 327 650 1.6E-81 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_00945 8b4bad60f139de7b56c4a9482261c17c 519 TIGRFAM TIGR01695 murJ_mviN: murein biosynthesis integral membrane protein MurJ 4 509 3.5E-141 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THITH_00945 8b4bad60f139de7b56c4a9482261c17c 519 PRINTS PR01806 Virulence factor MviN signature 53 69 6.8E-82 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THITH_00945 8b4bad60f139de7b56c4a9482261c17c 519 PRINTS PR01806 Virulence factor MviN signature 34 53 6.8E-82 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THITH_00945 8b4bad60f139de7b56c4a9482261c17c 519 PRINTS PR01806 Virulence factor MviN signature 158 179 6.8E-82 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THITH_00945 8b4bad60f139de7b56c4a9482261c17c 519 PRINTS PR01806 Virulence factor MviN signature 260 286 6.8E-82 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THITH_00945 8b4bad60f139de7b56c4a9482261c17c 519 PRINTS PR01806 Virulence factor MviN signature 134 158 6.8E-82 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THITH_00945 8b4bad60f139de7b56c4a9482261c17c 519 PRINTS PR01806 Virulence factor MviN signature 417 434 6.8E-82 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THITH_00945 8b4bad60f139de7b56c4a9482261c17c 519 PRINTS PR01806 Virulence factor MviN signature 358 377 6.8E-82 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THITH_00945 8b4bad60f139de7b56c4a9482261c17c 519 PIRSF PIRSF002869 1 519 1.4E-157 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THITH_00945 8b4bad60f139de7b56c4a9482261c17c 519 Pfam PF03023 MviN-like protein 30 471 3.9E-134 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THITH_00945 8b4bad60f139de7b56c4a9482261c17c 519 Hamap MF_02078 Probable lipid II flippase MurJ [murJ]. 4 510 20.479 T 13-10-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ THITH_01805 22bc86b03f07f3ed64623ea0a28874d3 709 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 287 493 6.7E-18 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THITH_01805 22bc86b03f07f3ed64623ea0a28874d3 709 Pfam PF01464 Transglycosylase SLT domain 520 626 7.6E-23 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 THITH_01805 22bc86b03f07f3ed64623ea0a28874d3 709 Gene3D G3DSA:3.40.190.10 357 452 2.2E-41 T 13-10-2018 THITH_01805 22bc86b03f07f3ed64623ea0a28874d3 709 Gene3D G3DSA:3.40.190.10 127 223 2.8E-51 T 13-10-2018 THITH_01805 22bc86b03f07f3ed64623ea0a28874d3 709 SUPERFAMILY SSF53850 262 494 2.55E-27 T 13-10-2018 THITH_01805 22bc86b03f07f3ed64623ea0a28874d3 709 SUPERFAMILY SSF53955 514 684 8.44E-39 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily THITH_01805 22bc86b03f07f3ed64623ea0a28874d3 709 Gene3D G3DSA:3.40.190.10 266 484 2.2E-41 T 13-10-2018 THITH_01805 22bc86b03f07f3ed64623ea0a28874d3 709 Gene3D G3DSA:3.40.190.10 37 248 2.8E-51 T 13-10-2018 THITH_01805 22bc86b03f07f3ed64623ea0a28874d3 709 SUPERFAMILY SSF53850 32 248 5.44E-33 T 13-10-2018 THITH_01805 22bc86b03f07f3ed64623ea0a28874d3 709 Gene3D G3DSA:1.10.530.10 512 693 6.2E-41 T 13-10-2018 THITH_01805 22bc86b03f07f3ed64623ea0a28874d3 709 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 67 247 2.5E-27 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THITH_01805 22bc86b03f07f3ed64623ea0a28874d3 709 SMART SM00062 271 495 2.9E-8 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THITH_01805 22bc86b03f07f3ed64623ea0a28874d3 709 SMART SM00062 59 263 1.4E-13 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THITH_11905 f998c82c3cd249bbc3d5ed5592ef5868 424 PIRSF PIRSF001549 1 422 1.0E-114 T 13-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 THITH_11905 f998c82c3cd249bbc3d5ed5592ef5868 424 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 2 420 32.633 T 13-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 THITH_11905 f998c82c3cd249bbc3d5ed5592ef5868 424 Gene3D G3DSA:3.40.50.800 325 420 4.3E-22 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily THITH_11905 f998c82c3cd249bbc3d5ed5592ef5868 424 Gene3D G3DSA:3.30.930.10 1 322 1.6E-115 T 13-10-2018 THITH_11905 f998c82c3cd249bbc3d5ed5592ef5868 424 Pfam PF13393 Histidyl-tRNA synthetase 9 310 1.1E-48 T 13-10-2018 THITH_11905 f998c82c3cd249bbc3d5ed5592ef5868 424 SUPERFAMILY SSF52954 325 422 1.64E-20 T 13-10-2018 THITH_11905 f998c82c3cd249bbc3d5ed5592ef5868 424 SUPERFAMILY SSF55681 4 318 2.49E-100 T 13-10-2018 THITH_11905 f998c82c3cd249bbc3d5ed5592ef5868 424 Pfam PF03129 Anticodon binding domain 341 420 3.5E-8 T 13-10-2018 IPR004154 Anticodon-binding THITH_11905 f998c82c3cd249bbc3d5ed5592ef5868 424 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 402 1.3E-147 T 13-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 THITH_11035 0630f39637516bc4dce5285b0c1f5869 1134 Gene3D G3DSA:3.40.50.300 529 756 2.0E-58 T 13-10-2018 THITH_11035 0630f39637516bc4dce5285b0c1f5869 1134 Pfam PF04851 Type III restriction enzyme, res subunit 350 507 3.4E-30 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THITH_11035 0630f39637516bc4dce5285b0c1f5869 1134 Pfam PF13643 Domain of unknown function (DUF4145) 22 112 8.3E-13 T 13-10-2018 IPR025285 Domain of unknown function DUF4145 THITH_11035 0630f39637516bc4dce5285b0c1f5869 1134 SUPERFAMILY SSF52540 304 559 1.26E-33 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_11035 0630f39637516bc4dce5285b0c1f5869 1134 Gene3D G3DSA:3.90.1570.30 186 332 3.2E-26 T 13-10-2018 THITH_11035 0630f39637516bc4dce5285b0c1f5869 1134 Pfam PF08463 EcoEI R protein C-terminal 974 1121 1.0E-14 T 13-10-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 THITH_11035 0630f39637516bc4dce5285b0c1f5869 1134 Gene3D G3DSA:3.40.50.300 333 521 7.6E-48 T 13-10-2018 THITH_11035 0630f39637516bc4dce5285b0c1f5869 1134 SMART SM00487 345 548 5.7E-19 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_11035 0630f39637516bc4dce5285b0c1f5869 1134 Pfam PF00271 Helicase conserved C-terminal domain 624 721 2.3E-7 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_11035 0630f39637516bc4dce5285b0c1f5869 1134 SUPERFAMILY SSF52540 471 723 2.05E-15 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 SUPERFAMILY SSF56091 8 321 1.58E-118 T 13-10-2018 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 Gene3D G3DSA:1.10.287.610 8 72 3.6E-28 T 13-10-2018 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 SMART SM00292 598 673 1.9E-11 T 13-10-2018 IPR001357 BRCT domain THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 SUPERFAMILY SSF52113 598 672 8.22E-16 T 13-10-2018 IPR036420 BRCT domain superfamily THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 Gene3D G3DSA:3.30.470.90 74 322 4.7E-97 T 13-10-2018 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 SMART SM00532 8 453 5.2E-256 T 13-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 Gene3D G3DSA:2.40.50.140 323 394 4.2E-33 T 13-10-2018 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 Pfam PF12826 Helix-hairpin-helix motif 515 578 9.5E-24 T 13-10-2018 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 16 667 2.5E-244 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 Gene3D G3DSA:1.10.150.20 437 510 1.9E-25 T 13-10-2018 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 120 149 - T 13-10-2018 IPR018239 NAD-dependent DNA ligase, active site THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 326 401 5.8E-33 T 13-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 Gene3D G3DSA:1.10.150.20 511 586 1.3E-30 T 13-10-2018 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 SUPERFAMILY SSF47781 409 588 1.45E-59 T 13-10-2018 IPR010994 RuvA domain 2-like THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 600 672 6.6E-11 T 13-10-2018 IPR001357 BRCT domain THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 SUPERFAMILY SSF50249 323 403 1.52E-26 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 SMART SM00278 485 504 69.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 SMART SM00278 517 536 120.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 SMART SM00278 549 568 43.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 SMART SM00278 451 470 21.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 336 351 - T 13-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 PIRSF PIRSF001604 2 673 4.2E-239 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 Gene3D G3DSA:3.40.50.10190 587 673 3.2E-22 T 13-10-2018 IPR036420 BRCT domain superfamily THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 Gene3D G3DSA:2.20.70.80 398 436 1.4E-14 T 13-10-2018 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 Hamap MF_01588 DNA ligase [ligA]. 7 672 51.847 T 13-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 413 439 4.7E-9 T 13-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 Pfam PF14520 Helix-hairpin-helix domain 451 501 0.0026 T 13-10-2018 THITH_09580 82b9166b118bff27eaa6ccc2dfe62489 673 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 11 323 1.4E-126 T 13-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 THITH_02465 35c4b305b472c128c6a0fdac921adbd7 381 Pfam PF00570 HRDC domain 214 281 3.2E-14 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 THITH_02465 35c4b305b472c128c6a0fdac921adbd7 381 SUPERFAMILY SSF47819 300 367 9.53E-7 T 13-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 THITH_02465 35c4b305b472c128c6a0fdac921adbd7 381 SMART SM00341 211 291 2.2E-7 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 THITH_02465 35c4b305b472c128c6a0fdac921adbd7 381 SMART SM00474 4 172 2.8E-35 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 THITH_02465 35c4b305b472c128c6a0fdac921adbd7 381 TIGRFAM TIGR01388 rnd: ribonuclease D 6 363 3.6E-110 T 13-10-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 THITH_02465 35c4b305b472c128c6a0fdac921adbd7 381 Gene3D G3DSA:3.30.420.10 3 193 6.5E-67 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_02465 35c4b305b472c128c6a0fdac921adbd7 381 SUPERFAMILY SSF47819 192 298 1.94E-27 T 13-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 THITH_02465 35c4b305b472c128c6a0fdac921adbd7 381 Gene3D G3DSA:1.10.150.80 196 295 7.6E-26 T 13-10-2018 THITH_02465 35c4b305b472c128c6a0fdac921adbd7 381 Hamap MF_01899 Ribonuclease D [rnd]. 4 366 40.935 T 13-10-2018 IPR006292 Ribonuclease D GO:0008033|GO:0008408|GO:0033890 THITH_02465 35c4b305b472c128c6a0fdac921adbd7 381 SUPERFAMILY SSF53098 6 210 1.99E-65 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_02465 35c4b305b472c128c6a0fdac921adbd7 381 Pfam PF01612 3'-5' exonuclease 7 172 1.0E-36 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 THITH_01755 a18accd029fb5282425e7a57d80b9920 517 Gene3D G3DSA:3.40.120.10 279 403 3.0E-29 T 13-10-2018 THITH_01755 a18accd029fb5282425e7a57d80b9920 517 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 286 399 9.1E-13 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_01755 a18accd029fb5282425e7a57d80b9920 517 Gene3D G3DSA:3.40.120.10 13 162 2.7E-33 T 13-10-2018 THITH_01755 a18accd029fb5282425e7a57d80b9920 517 SUPERFAMILY SSF53738 286 399 1.33E-16 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_01755 a18accd029fb5282425e7a57d80b9920 517 SUPERFAMILY SSF53738 19 204 7.46E-29 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_01755 a18accd029fb5282425e7a57d80b9920 517 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 15 142 1.8E-29 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_01755 a18accd029fb5282425e7a57d80b9920 517 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 196 281 1.4E-21 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_01755 a18accd029fb5282425e7a57d80b9920 517 Gene3D G3DSA:3.40.120.10 199 275 2.9E-26 T 13-10-2018 THITH_01755 a18accd029fb5282425e7a57d80b9920 517 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 113 127 1.2E-19 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_01755 a18accd029fb5282425e7a57d80b9920 517 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 232 245 1.2E-19 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_01755 a18accd029fb5282425e7a57d80b9920 517 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 261 276 1.2E-19 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_01755 a18accd029fb5282425e7a57d80b9920 517 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 197 216 1.2E-19 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_01755 a18accd029fb5282425e7a57d80b9920 517 SUPERFAMILY SSF53738 182 283 5.1E-24 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 Pfam PF13583 Metallo-peptidase family M12B Reprolysin-like 219 408 1.5E-18 T 13-10-2018 THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 SUPERFAMILY SSF49265 874 981 5.02E-19 T 13-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 Gene3D G3DSA:2.60.40.10 885 975 8.4E-20 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 SUPERFAMILY SSF55486 215 402 2.38E-14 T 13-10-2018 THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 Pfam PF00041 Fibronectin type III domain 884 965 3.6E-9 T 13-10-2018 IPR003961 Fibronectin type III GO:0005515 THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 SMART SM00060 580 663 110.0 T 13-10-2018 IPR003961 Fibronectin type III GO:0005515 THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 SMART SM00060 882 965 1.2E-10 T 13-10-2018 IPR003961 Fibronectin type III GO:0005515 THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 SMART SM00060 782 866 0.0019 T 13-10-2018 IPR003961 Fibronectin type III GO:0005515 THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 SMART SM00060 1233 1315 0.4 T 13-10-2018 IPR003961 Fibronectin type III GO:0005515 THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 Gene3D G3DSA:2.60.40.10 1234 1326 3.8E-11 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 SUPERFAMILY SSF49265 1240 1325 6.97E-6 T 13-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 1002 1069 1.8E-8 T 13-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 Pfam PF15780 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin 688 763 1.6E-9 T 13-10-2018 IPR031549 Abnormal spindle-like microcephaly-associated protein, ASH domain THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 Pfam PF07603 Protein of unknown function (DUF1566) 1345 1487 3.1E-17 T 13-10-2018 IPR011460 Protein of unknown function DUF1566 THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 Gene3D G3DSA:3.40.390.10 197 373 7.3E-8 T 13-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 Gene3D G3DSA:2.60.120.380 983 1084 1.1E-32 T 13-10-2018 THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 Gene3D G3DSA:2.60.40.10 777 884 5.2E-9 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 Gene3D G3DSA:2.60.120.380 450 575 2.8E-5 T 13-10-2018 THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 Gene3D G3DSA:2.60.40.10 677 776 3.8E-17 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_09820 56cc63be2d3cb5343fda95a8a6ee052f 1495 SUPERFAMILY SSF49265 599 867 8.04E-13 T 13-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 THITH_03140 e8fbb802eece75f1abe3b3df74837ad2 796 TIGRFAM TIGR02242 tail_TIGR02242: phage tail protein domain 524 627 2.5E-16 T 13-10-2018 IPR011748 Uncharacterised protein family, phage tail-like THITH_03140 e8fbb802eece75f1abe3b3df74837ad2 796 SUPERFAMILY SSF82171 79 238 1.26E-5 T 13-10-2018 THITH_03140 e8fbb802eece75f1abe3b3df74837ad2 796 Pfam PF09684 Phage tail protein (Tail_P2_I) 525 610 3.9E-10 T 13-10-2018 IPR006521 Tail protein I THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 Pfam PF00308 Bacterial dnaA protein 110 327 1.1E-96 T 13-10-2018 IPR013317 Chromosomal replication initiator protein DnaA THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 SUPERFAMILY SSF48295 342 444 1.28E-35 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 Gene3D G3DSA:3.30.300.180 4 104 3.8E-22 T 13-10-2018 IPR038454 DnaA, N-terminal domain superfamily THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 SMART SM00382 142 273 4.0E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 Gene3D G3DSA:1.10.8.60 276 346 8.2E-24 T 13-10-2018 THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 SUPERFAMILY SSF52540 109 321 2.67E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 Gene3D G3DSA:3.40.50.300 105 274 4.5E-48 T 13-10-2018 THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 Gene3D G3DSA:1.10.1750.10 352 445 3.5E-36 T 13-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 SMART SM00760 353 422 3.7E-43 T 13-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 ProSitePatterns PS01008 DnaA protein signature. 403 422 - T 13-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 355 422 4.2E-31 T 13-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 Pfam PF11638 DnaA N-terminal domain 4 62 1.9E-15 T 13-10-2018 IPR024633 DnaA N-terminal domain THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 7 443 1.6E-178 T 13-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 143 163 3.7E-53 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 207 221 3.7E-53 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 175 189 3.7E-53 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 241 268 3.7E-53 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 403 422 3.7E-53 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like THITH_00005 49f36bdef1ddeee5581fa94486eb46a7 445 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 4 444 33.044 T 13-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 THITH_02440 9e761f33511951c46169defae088162d 249 Pfam PF06293 Lipopolysaccharide kinase (Kdo/WaaP) family 57 235 5.7E-41 T 13-10-2018 THITH_02440 9e761f33511951c46169defae088162d 249 SUPERFAMILY SSF56112 88 223 8.9E-15 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily THITH_02440 9e761f33511951c46169defae088162d 249 Hamap MF_00521 3-deoxy-D-manno-octulosonic acid kinase [kdkA]. 1 237 26.903 T 13-10-2018 IPR022826 3-deoxy-D-manno-octulosonic acid kinase GO:0016773 KEGG: 00540+2.7.1.166|MetaCyc: PWY-7675|MetaCyc: PWY-7676 THITH_02440 9e761f33511951c46169defae088162d 249 Gene3D G3DSA:1.10.510.10 141 240 4.7E-10 T 13-10-2018 THITH_13350 35d822d23d17eeb00240338fb2551be1 87 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 50 6.8E-21 T 13-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 THITH_13350 35d822d23d17eeb00240338fb2551be1 87 Pfam PF02416 mttA/Hcf106 family 6 51 1.7E-16 T 13-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 THITH_13350 35d822d23d17eeb00240338fb2551be1 87 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 3 79 21.164 T 13-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 Pfam PF00679 Elongation factor G C-terminus 396 476 2.1E-22 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 Gene3D G3DSA:3.30.70.870 306 590 3.0E-132 T 13-10-2018 THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 Gene3D G3DSA:2.40.30.10 199 299 3.9E-31 T 13-10-2018 THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 134 2.4E-25 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 Gene3D G3DSA:2.40.50.250 483 599 3.0E-132 T 13-10-2018 THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 SUPERFAMILY SSF54980 398 513 3.88E-27 T 13-10-2018 IPR035647 EF-G domain III/V-like THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 SUPERFAMILY SSF54980 302 387 1.19E-14 T 13-10-2018 IPR035647 EF-G domain III/V-like THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 5 599 3.5E-286 T 13-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 PRINTS PR00315 GTP-binding elongation factor signature 87 98 2.7E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 PRINTS PR00315 GTP-binding elongation factor signature 51 59 2.7E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 PRINTS PR00315 GTP-binding elongation factor signature 71 81 2.7E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 PRINTS PR00315 GTP-binding elongation factor signature 7 20 2.7E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 PRINTS PR00315 GTP-binding elongation factor signature 123 132 2.7E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 SUPERFAMILY SSF52540 4 207 3.21E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 SUPERFAMILY SSF50447 151 299 3.31E-31 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 Gene3D G3DSA:3.30.70.240 389 482 3.0E-132 T 13-10-2018 THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 Pfam PF00009 Elongation factor Tu GTP binding domain 4 195 1.0E-54 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 Pfam PF03144 Elongation factor Tu domain 2 222 289 2.0E-7 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THITH_15725 8dd3a3c2236f879b408e1d295bb8227d 605 Gene3D G3DSA:3.40.50.300 2 198 1.9E-66 T 13-10-2018 THITH_13645 422c4d223158a287b84bce1255ce66fd 149 PRINTS PR00502 NUDIX hydrolase family signature 38 52 5.2E-8 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 THITH_13645 422c4d223158a287b84bce1255ce66fd 149 PRINTS PR00502 NUDIX hydrolase family signature 52 67 5.2E-8 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 THITH_13645 422c4d223158a287b84bce1255ce66fd 149 Gene3D G3DSA:3.90.79.10 4 136 4.6E-39 T 13-10-2018 THITH_13645 422c4d223158a287b84bce1255ce66fd 149 SUPERFAMILY SSF55811 5 135 1.12E-30 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 THITH_13645 422c4d223158a287b84bce1255ce66fd 149 Pfam PF00293 NUDIX domain 11 130 1.9E-20 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 THITH_06520 88be55d176959deaf10f7f3042f723a2 384 Pfam PF13439 Glycosyltransferase Family 4 15 167 3.6E-13 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 THITH_06520 88be55d176959deaf10f7f3042f723a2 384 Gene3D G3DSA:3.40.50.2000 164 355 5.4E-62 T 13-10-2018 THITH_06520 88be55d176959deaf10f7f3042f723a2 384 Pfam PF00534 Glycosyl transferases group 1 180 353 7.4E-33 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 THITH_06520 88be55d176959deaf10f7f3042f723a2 384 Gene3D G3DSA:3.40.50.2000 67 372 5.4E-62 T 13-10-2018 THITH_06520 88be55d176959deaf10f7f3042f723a2 384 SUPERFAMILY SSF53756 5 372 1.3E-74 T 13-10-2018 THITH_10150 e04012d01e574238d2a475f04f38c7bd 600 SUPERFAMILY SSF50939 193 421 7.01E-14 T 13-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 THITH_10150 e04012d01e574238d2a475f04f38c7bd 600 Gene3D G3DSA:2.120.10.10 198 448 9.2E-9 T 13-10-2018 THITH_14235 1228acab16a194e4629aae969ce86827 105 ProSitePatterns PS01108 Ribosomal protein L24 signature. 7 24 - T 13-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14235 1228acab16a194e4629aae969ce86827 105 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 2 97 20.285 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14235 1228acab16a194e4629aae969ce86827 105 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 103 3.7E-37 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14235 1228acab16a194e4629aae969ce86827 105 SMART SM00739 3 30 0.0032 T 13-10-2018 IPR005824 KOW THITH_14235 1228acab16a194e4629aae969ce86827 105 Pfam PF00467 KOW motif 6 35 4.9E-5 T 13-10-2018 IPR005824 KOW THITH_14235 1228acab16a194e4629aae969ce86827 105 Gene3D G3DSA:2.30.30.30 1 104 2.1E-37 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 THITH_14235 1228acab16a194e4629aae969ce86827 105 SUPERFAMILY SSF50104 3 102 1.39E-32 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily THITH_14235 1228acab16a194e4629aae969ce86827 105 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 102 3.2E-26 T 13-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_11745 0010ccb4191fed942725ec88a0275b68 359 SUPERFAMILY SSF56042 168 347 2.69E-44 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THITH_11745 0010ccb4191fed942725ec88a0275b68 359 Gene3D G3DSA:3.90.650.10 168 351 8.5E-48 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THITH_11745 0010ccb4191fed942725ec88a0275b68 359 Gene3D G3DSA:3.30.1330.10 3 166 8.8E-51 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THITH_11745 0010ccb4191fed942725ec88a0275b68 359 SUPERFAMILY SSF55326 11 165 5.36E-42 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THITH_11745 0010ccb4191fed942725ec88a0275b68 359 Hamap MF_00625 Selenide, water dikinase [selD]. 9 354 42.19 T 13-10-2018 IPR023061 Selenophosphate synthetase, class I GO:0004756|GO:0005524|GO:0016260 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 THITH_11745 0010ccb4191fed942725ec88a0275b68 359 Pfam PF00586 AIR synthase related protein, N-terminal domain 54 161 7.0E-22 T 13-10-2018 IPR016188 PurM-like, N-terminal domain THITH_11745 0010ccb4191fed942725ec88a0275b68 359 Pfam PF02769 AIR synthase related protein, C-terminal domain 173 346 1.7E-28 T 13-10-2018 IPR010918 PurM-like, C-terminal domain THITH_11745 0010ccb4191fed942725ec88a0275b68 359 PIRSF PIRSF036407 4 353 4.0E-108 T 13-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 THITH_11745 0010ccb4191fed942725ec88a0275b68 359 TIGRFAM TIGR00476 selD: selenide, water dikinase 11 320 2.7E-124 T 13-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 THITH_15000 8debfb25f3e4d6cb2753a4357d7f93a0 594 TIGRFAM TIGR01391 dnaG: DNA primase 5 409 6.9E-129 T 13-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 THITH_15000 8debfb25f3e4d6cb2753a4357d7f93a0 594 Pfam PF08275 DNA primase catalytic core, N-terminal domain 122 243 7.9E-34 T 13-10-2018 IPR013264 DNA primase, catalytic core, N-terminal THITH_15000 8debfb25f3e4d6cb2753a4357d7f93a0 594 Gene3D G3DSA:1.10.860.10 457 587 2.9E-10 T 13-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal THITH_15000 8debfb25f3e4d6cb2753a4357d7f93a0 594 SMART SM00493 251 322 6.0E-18 T 13-10-2018 IPR006171 TOPRIM domain THITH_15000 8debfb25f3e4d6cb2753a4357d7f93a0 594 Pfam PF13662 Toprim domain 251 317 4.8E-15 T 13-10-2018 IPR006171 TOPRIM domain THITH_15000 8debfb25f3e4d6cb2753a4357d7f93a0 594 Pfam PF08278 DNA primase DnaG DnaB-binding 461 580 1.7E-14 T 13-10-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 THITH_15000 8debfb25f3e4d6cb2753a4357d7f93a0 594 SUPERFAMILY SSF117023 460 582 2.22E-10 T 13-10-2018 THITH_15000 8debfb25f3e4d6cb2753a4357d7f93a0 594 Gene3D G3DSA:3.90.580.10 1 101 2.7E-39 T 13-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 THITH_15000 8debfb25f3e4d6cb2753a4357d7f93a0 594 Gene3D G3DSA:3.40.1360.10 233 358 1.4E-39 T 13-10-2018 THITH_15000 8debfb25f3e4d6cb2753a4357d7f93a0 594 Hamap MF_00974 DNA primase [dnaG]. 4 579 27.103 T 13-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 THITH_15000 8debfb25f3e4d6cb2753a4357d7f93a0 594 Gene3D G3DSA:3.90.980.10 109 232 1.8E-35 T 13-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily THITH_15000 8debfb25f3e4d6cb2753a4357d7f93a0 594 SUPERFAMILY SSF57783 4 100 9.01E-38 T 13-10-2018 THITH_15000 8debfb25f3e4d6cb2753a4357d7f93a0 594 SMART SM00400 36 90 8.4E-33 T 13-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 THITH_15000 8debfb25f3e4d6cb2753a4357d7f93a0 594 SUPERFAMILY SSF56731 112 414 6.37E-93 T 13-10-2018 THITH_15000 8debfb25f3e4d6cb2753a4357d7f93a0 594 Pfam PF10410 DnaB-helicase binding domain of primase 364 413 2.1E-7 T 13-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 THITH_15000 8debfb25f3e4d6cb2753a4357d7f93a0 594 Pfam PF01807 CHC2 zinc finger 6 100 3.0E-38 T 13-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 THITH_07695 8796f1cfee3cf011f8d1cc51096634a5 207 SUPERFAMILY SSF52141 7 206 3.92E-49 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THITH_07695 8796f1cfee3cf011f8d1cc51096634a5 207 Gene3D G3DSA:3.40.470.10 5 206 1.5E-65 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THITH_07695 8796f1cfee3cf011f8d1cc51096634a5 207 SMART SM00987 33 199 1.8E-33 T 13-10-2018 THITH_07695 8796f1cfee3cf011f8d1cc51096634a5 207 SMART SM00986 33 199 1.8E-33 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THITH_07695 8796f1cfee3cf011f8d1cc51096634a5 207 Pfam PF03167 Uracil DNA glycosylase superfamily 33 199 3.9E-34 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THITH_03630 35983d0a5fa9a7dbaa9f77c960c2632f 164 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 6.0E-34 T 13-10-2018 THITH_03630 35983d0a5fa9a7dbaa9f77c960c2632f 164 SUPERFAMILY SSF55021 80 161 2.87E-25 T 13-10-2018 THITH_03630 35983d0a5fa9a7dbaa9f77c960c2632f 164 Pfam PF10369 Small subunit of acetolactate synthase 84 158 3.9E-26 T 13-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 THITH_03630 35983d0a5fa9a7dbaa9f77c960c2632f 164 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 1 159 4.6E-63 T 13-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 THITH_03630 35983d0a5fa9a7dbaa9f77c960c2632f 164 Gene3D G3DSA:3.30.70.260 1 78 7.9E-36 T 13-10-2018 THITH_03630 35983d0a5fa9a7dbaa9f77c960c2632f 164 Pfam PF13710 ACT domain 12 72 4.0E-16 T 13-10-2018 THITH_03630 35983d0a5fa9a7dbaa9f77c960c2632f 164 Gene3D G3DSA:3.30.70.1150 83 164 4.3E-27 T 13-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal THITH_03630 35983d0a5fa9a7dbaa9f77c960c2632f 164 SUPERFAMILY SSF55021 1 75 1.37E-22 T 13-10-2018 THITH_15745 a7dc61d6ec99d608f959476363a0cf08 136 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 94 129 7.9E-12 T 13-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 THITH_15745 a7dc61d6ec99d608f959476363a0cf08 136 Gene3D G3DSA:1.20.120.910 3 135 4.1E-38 T 13-10-2018 THITH_15745 a7dc61d6ec99d608f959476363a0cf08 136 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 17 125 2.4E-45 T 13-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 THITH_15745 a7dc61d6ec99d608f959476363a0cf08 136 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 99 123 - T 13-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site THITH_15745 a7dc61d6ec99d608f959476363a0cf08 136 SUPERFAMILY SSF109635 5 94 6.15E-32 T 13-10-2018 IPR037187 DksA, N-terminal domain superfamily THITH_15745 a7dc61d6ec99d608f959476363a0cf08 136 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 13 135 29.034 T 13-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 THITH_15745 a7dc61d6ec99d608f959476363a0cf08 136 SUPERFAMILY SSF57716 96 133 1.57E-8 T 13-10-2018 THITH_02915 ec8c813b2bb2fa5d1e0afc811027415b 151 Pfam PF02472 Biopolymer transport protein ExbD/TolR 14 145 8.8E-23 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 THITH_02915 ec8c813b2bb2fa5d1e0afc811027415b 151 Gene3D G3DSA:3.30.420.270 64 136 1.7E-14 T 13-10-2018 THITH_02915 ec8c813b2bb2fa5d1e0afc811027415b 151 Hamap MF_02203 Tol-Pal system protein TolR [tolR]. 8 144 27.071 T 13-10-2018 IPR014168 Tol-Pal system protein TolR GO:0015031|GO:0016021 THITH_02915 ec8c813b2bb2fa5d1e0afc811027415b 151 TIGRFAM TIGR02801 tolR: protein TolR 16 144 8.0E-41 T 13-10-2018 IPR014168 Tol-Pal system protein TolR GO:0015031|GO:0016021 THITH_01860 43341923bd7aaee3bb63c310c677d02b 1064 SUPERFAMILY SSF53098 592 1064 4.55E-67 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_01860 43341923bd7aaee3bb63c310c677d02b 1064 Gene3D G3DSA:3.30.420.10 817 1062 8.6E-43 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_01860 43341923bd7aaee3bb63c310c677d02b 1064 SMART SM00950 739 1052 0.004 T 13-10-2018 IPR003165 Piwi domain GO:0003676 THITH_01860 43341923bd7aaee3bb63c310c677d02b 1064 SUPERFAMILY SSF52467 29 250 1.5E-9 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily THITH_01860 43341923bd7aaee3bb63c310c677d02b 1064 Pfam PF13289 SIR2-like domain 149 257 2.5E-7 T 13-10-2018 IPR039444 SIR2-like domain THITH_01145 1d00c1ae956bbd4e50c7a9ad41b7f189 390 Pfam PF02661 Fic/DOC family 133 237 3.6E-21 T 13-10-2018 IPR003812 Fido domain THITH_01145 1d00c1ae956bbd4e50c7a9ad41b7f189 390 SUPERFAMILY SSF140931 109 301 6.67E-46 T 13-10-2018 IPR036597 Fido-like domain superfamily THITH_01145 1d00c1ae956bbd4e50c7a9ad41b7f189 390 Pfam PF13784 Fic/DOC family N-terminal 44 124 9.2E-28 T 13-10-2018 IPR025758 Fic/DOC N-terminal THITH_01145 1d00c1ae956bbd4e50c7a9ad41b7f189 390 Gene3D G3DSA:1.10.3290.10 68 299 9.6E-57 T 13-10-2018 IPR036597 Fido-like domain superfamily THITH_01145 1d00c1ae956bbd4e50c7a9ad41b7f189 390 SUPERFAMILY SSF46785 321 369 3.29E-5 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_01145 1d00c1ae956bbd4e50c7a9ad41b7f189 390 PIRSF PIRSF038925 18 386 6.4E-115 T 13-10-2018 IPR026287 Adenosine monophosphate-protein transferase THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 Pfam PF12156 Putative metal-binding domain of cation transport ATPase 15 99 2.4E-25 T 13-10-2018 IPR021993 Putative metal-binding domain of cation transport ATPase THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 528 534 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 SUPERFAMILY SSF56784 524 820 6.78E-48 T 13-10-2018 IPR036412 HAD-like superfamily THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 SUPERFAMILY SSF81660 545 655 2.32E-20 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 Gene3D G3DSA:3.30.70.100 108 178 2.0E-15 T 13-10-2018 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 720 739 2.1E-22 T 13-10-2018 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 526 540 2.1E-22 T 13-10-2018 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 667 677 2.1E-22 T 13-10-2018 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 377 391 2.1E-22 T 13-10-2018 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 645 656 2.1E-22 T 13-10-2018 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 743 755 2.1E-22 T 13-10-2018 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 Pfam PF00702 haloacid dehalogenase-like hydrolase 523 734 9.5E-36 T 13-10-2018 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 Pfam PF00403 Heavy-metal-associated domain 114 172 3.9E-9 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 Gene3D G3DSA:2.70.150.20 320 432 1.0E-33 T 13-10-2018 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 247 823 1.3E-146 T 13-10-2018 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 SUPERFAMILY SSF55008 110 180 1.96E-18 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 264 822 1.1E-161 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 SUPERFAMILY SSF81665 273 798 2.22E-10 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 Gene3D G3DSA:3.40.1110.10 537 652 2.7E-71 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 Pfam PF00122 E1-E2 ATPase 329 505 2.1E-46 T 13-10-2018 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 Gene3D G3DSA:3.40.50.1000 521 770 2.7E-71 T 13-10-2018 IPR023214 HAD superfamily THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 SUPERFAMILY SSF81653 337 426 1.03E-23 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 THITH_16495 4957f51d5a6f043b12ee1c7a803d0455 850 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 299 804 2.4E-71 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THITH_16390 296b09b06af78c38478c6a2d03b18df2 684 SUPERFAMILY SSF53955 480 641 2.53E-42 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily THITH_16390 296b09b06af78c38478c6a2d03b18df2 684 Gene3D G3DSA:1.25.20.10 28 388 5.3E-112 T 13-10-2018 THITH_16390 296b09b06af78c38478c6a2d03b18df2 684 Gene3D G3DSA:1.10.1240.20 405 473 3.5E-8 T 13-10-2018 IPR037061 Lytic transglycosylase, superhelical linker domain superfamily GO:0004553|GO:0042597 THITH_16390 296b09b06af78c38478c6a2d03b18df2 684 Gene3D G3DSA:1.10.530.10 475 635 2.5E-44 T 13-10-2018 THITH_16390 296b09b06af78c38478c6a2d03b18df2 684 SUPERFAMILY SSF48435 30 478 6.67E-124 T 13-10-2018 IPR008939 Lytic transglycosylase, superhelical U-shaped GO:0004553|GO:0042597 THITH_16390 296b09b06af78c38478c6a2d03b18df2 684 Pfam PF14718 Soluble lytic murein transglycosylase L domain 407 473 4.1E-23 T 13-10-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 THITH_16390 296b09b06af78c38478c6a2d03b18df2 684 Pfam PF01464 Transglycosylase SLT domain 485 595 6.3E-25 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 THITH_08780 c51aa4268e3c2f1a21541ffa4f01321e 371 Gene3D G3DSA:2.40.30.10 281 363 1.5E-24 T 13-10-2018 THITH_08780 c51aa4268e3c2f1a21541ffa4f01321e 371 Gene3D G3DSA:3.40.50.620 1 211 1.2E-84 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_08780 c51aa4268e3c2f1a21541ffa4f01321e 371 Pfam PF03054 tRNA methyl transferase 7 358 1.1E-125 T 13-10-2018 THITH_08780 c51aa4268e3c2f1a21541ffa4f01321e 371 Gene3D G3DSA:2.30.30.280 212 279 3.3E-24 T 13-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 THITH_08780 c51aa4268e3c2f1a21541ffa4f01321e 371 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 6 359 36.629 T 13-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 THITH_08780 c51aa4268e3c2f1a21541ffa4f01321e 371 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 7 358 4.7E-120 T 13-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 THITH_08780 c51aa4268e3c2f1a21541ffa4f01321e 371 SUPERFAMILY SSF52402 5 243 2.87E-52 T 13-10-2018 THITH_11130 62a1cd5a573172082a64136cfca3e35f 69 Gene3D G3DSA:3.40.50.1010 6 64 1.3E-17 T 13-10-2018 THITH_11130 62a1cd5a573172082a64136cfca3e35f 69 SUPERFAMILY SSF88723 17 60 5.89E-6 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_15985 6ba6b0385fde08ae60762735cf8dd2bf 359 SUPERFAMILY SSF143631 38 339 7.15E-70 T 13-10-2018 IPR003374 ApbE-like superfamily THITH_15985 6ba6b0385fde08ae60762735cf8dd2bf 359 Pfam PF02424 ApbE family 44 316 1.4E-66 T 13-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 THITH_15985 6ba6b0385fde08ae60762735cf8dd2bf 359 PIRSF PIRSF006268 12 345 1.4E-63 T 13-10-2018 IPR024932 Flavin transferase ApbE GO:0017013 THITH_15985 6ba6b0385fde08ae60762735cf8dd2bf 359 Gene3D G3DSA:3.10.520.20 26 345 6.7E-77 T 13-10-2018 THITH_11570 88e5cb64341cc235144be27b31dd4d2b 285 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 282 14.715 T 13-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 THITH_11570 88e5cb64341cc235144be27b31dd4d2b 285 Pfam PF02673 Bacitracin resistance protein BacA 6 276 4.7E-66 T 13-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 619 634 1.6E-24 T 13-10-2018 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 636 651 1.6E-24 T 13-10-2018 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 466 485 1.6E-24 T 13-10-2018 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 672 684 1.6E-24 T 13-10-2018 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 179 738 7.1E-142 T 13-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 SUPERFAMILY SSF52009 299 420 2.49E-28 T 13-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 SMART SM00065 17 164 4.1E-27 T 13-10-2018 IPR003018 GAF domain GO:0005515 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 Pfam PF01590 GAF domain 19 154 1.2E-18 T 13-10-2018 IPR003018 GAF domain GO:0005515 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 Gene3D G3DSA:3.20.20.60 407 745 9.5E-111 T 13-10-2018 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 SUPERFAMILY SSF55781 2 162 3.49E-34 T 13-10-2018 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 619 637 - T 13-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 427 711 6.9E-99 T 13-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 Gene3D G3DSA:1.10.274.10 196 320 3.2E-64 T 13-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 SUPERFAMILY SSF51621 430 712 8.38E-102 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 SUPERFAMILY SSF47831 204 316 1.26E-29 T 13-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 Gene3D G3DSA:3.30.450.40 1 164 8.4E-50 T 13-10-2018 IPR029016 GAF-like domain superfamily THITH_02535 16420e15c80787ec9954b1857084f9b5 755 Pfam PF00391 PEP-utilising enzyme, mobile domain 325 398 1.4E-16 T 13-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 Pfam PF05524 PEP-utilising enzyme, N-terminal 178 300 3.0E-26 T 13-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 THITH_02535 16420e15c80787ec9954b1857084f9b5 755 Gene3D G3DSA:3.50.30.10 179 406 3.2E-64 T 13-10-2018 THITH_12115 fa06d106f70a30f916d3e85cecbf6344 126 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 123 9.0E-18 T 13-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 THITH_12115 fa06d106f70a30f916d3e85cecbf6344 126 Gene3D G3DSA:3.90.470.20 1 124 7.2E-35 T 13-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 THITH_12115 fa06d106f70a30f916d3e85cecbf6344 126 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 123 1.2E-24 T 13-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 THITH_12115 fa06d106f70a30f916d3e85cecbf6344 126 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 124 23.226 T 13-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 THITH_12115 fa06d106f70a30f916d3e85cecbf6344 126 SUPERFAMILY SSF56214 1 123 1.83E-27 T 13-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 THITH_12115 fa06d106f70a30f916d3e85cecbf6344 126 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 124 3.0E-31 T 13-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 THITH_12115 fa06d106f70a30f916d3e85cecbf6344 126 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 118 1.7E-19 T 13-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 THITH_13640 761914c7178208df9f4654cbbaa28473 438 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 195 256 3.6E-15 T 13-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 THITH_13640 761914c7178208df9f4654cbbaa28473 438 Gene3D G3DSA:3.30.460.10 3 164 2.7E-58 T 13-10-2018 THITH_13640 761914c7178208df9f4654cbbaa28473 438 SUPERFAMILY SSF81891 165 402 2.88E-43 T 13-10-2018 THITH_13640 761914c7178208df9f4654cbbaa28473 438 Hamap MF_00957 Poly(A) polymerase I [pcnB]. 2 435 35.959 T 13-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 THITH_13640 761914c7178208df9f4654cbbaa28473 438 TIGRFAM TIGR01942 pcnB: poly(A) polymerase 5 433 2.1E-148 T 13-10-2018 IPR010206 Poly(A) polymerase I GO:0003723|GO:0004652|GO:0006378 THITH_13640 761914c7178208df9f4654cbbaa28473 438 Pfam PF01743 Poly A polymerase head domain 38 167 6.9E-36 T 13-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 THITH_13640 761914c7178208df9f4654cbbaa28473 438 Pfam PF12626 Polymerase A arginine-rich C-terminus 313 432 5.4E-40 T 13-10-2018 IPR025866 Polymerase A arginine-rich C-terminal domain THITH_13640 761914c7178208df9f4654cbbaa28473 438 SUPERFAMILY SSF81301 6 163 5.56E-40 T 13-10-2018 THITH_13640 761914c7178208df9f4654cbbaa28473 438 Gene3D G3DSA:1.10.3090.10 165 413 2.0E-82 T 13-10-2018 THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 Gene3D G3DSA:3.30.70.270 283 451 3.9E-63 T 13-10-2018 THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 SUPERFAMILY SSF55073 284 442 9.42E-52 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 Pfam PF13426 PAS domain 165 267 1.5E-13 T 13-10-2018 IPR000014 PAS domain THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 276 439 1.2E-48 T 13-10-2018 IPR000160 GGDEF domain THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 SMART SM00091 36 102 3.7E-4 T 13-10-2018 IPR000014 PAS domain THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 SMART SM00091 154 220 0.0034 T 13-10-2018 IPR000014 PAS domain THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 SUPERFAMILY SSF141868 457 697 2.88E-69 T 13-10-2018 IPR035919 EAL domain superfamily THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 Pfam PF08448 PAS fold 42 122 1.3E-5 T 13-10-2018 IPR013656 PAS fold-4 THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 Pfam PF00990 Diguanylate cyclase, GGDEF domain 279 436 5.7E-51 T 13-10-2018 IPR000160 GGDEF domain THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 SMART SM00267 268 440 3.8E-67 T 13-10-2018 IPR000160 GGDEF domain THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 SUPERFAMILY SSF55785 37 128 1.93E-11 T 13-10-2018 IPR035965 PAS domain superfamily THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 Gene3D G3DSA:3.30.450.20 31 145 1.1E-9 T 13-10-2018 THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 Gene3D G3DSA:3.20.20.450 452 705 4.9E-73 T 13-10-2018 IPR035919 EAL domain superfamily THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 Pfam PF00563 EAL domain 456 692 7.0E-61 T 13-10-2018 IPR001633 EAL domain THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 165 274 8.6E-17 T 13-10-2018 IPR000014 PAS domain THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 Gene3D G3DSA:3.30.450.20 152 282 2.9E-31 T 13-10-2018 THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 SMART SM00052 450 697 6.3E-77 T 13-10-2018 IPR001633 EAL domain THITH_03900 d19ac8b2dd5304bce4d92835770232f0 716 SUPERFAMILY SSF55785 163 266 1.27E-25 T 13-10-2018 IPR035965 PAS domain superfamily THITH_04850 ba2db584a52e62b07c88d701a69b2c26 455 Gene3D G3DSA:1.10.8.60 316 381 1.1E-5 T 13-10-2018 THITH_04850 ba2db584a52e62b07c88d701a69b2c26 455 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 166 179 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THITH_04850 ba2db584a52e62b07c88d701a69b2c26 455 Pfam PF00158 Sigma-54 interaction domain 146 309 2.0E-44 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THITH_04850 ba2db584a52e62b07c88d701a69b2c26 455 Gene3D G3DSA:1.10.10.60 399 449 2.3E-13 T 13-10-2018 THITH_04850 ba2db584a52e62b07c88d701a69b2c26 455 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 228 243 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THITH_04850 ba2db584a52e62b07c88d701a69b2c26 455 SMART SM00382 162 306 2.1E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_04850 ba2db584a52e62b07c88d701a69b2c26 455 Gene3D G3DSA:3.40.50.300 140 314 4.3E-51 T 13-10-2018 THITH_04850 ba2db584a52e62b07c88d701a69b2c26 455 SUPERFAMILY SSF46689 349 447 3.29E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_04850 ba2db584a52e62b07c88d701a69b2c26 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 412 429 3.8E-8 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_04850 ba2db584a52e62b07c88d701a69b2c26 455 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 429 449 3.8E-8 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_04850 ba2db584a52e62b07c88d701a69b2c26 455 SUPERFAMILY SSF52540 149 368 1.3E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_04850 ba2db584a52e62b07c88d701a69b2c26 455 Pfam PF02954 Bacterial regulatory protein, Fis family 410 445 6.0E-13 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_11295 8d7b9da2fad6739a1cd17f18924c6529 66 Pfam PF07311 Dodecin 3 66 8.1E-27 T 13-10-2018 IPR009923 Dodecin THITH_11295 8d7b9da2fad6739a1cd17f18924c6529 66 SUPERFAMILY SSF89807 1 66 1.83E-22 T 13-10-2018 IPR036694 Dodecin-like superfamily THITH_11295 8d7b9da2fad6739a1cd17f18924c6529 66 Gene3D G3DSA:3.30.1660.10 1 66 2.1E-23 T 13-10-2018 IPR025543 Dodecin-like THITH_06405 f08dafdb0ec8fd166390137557ea42e4 277 Gene3D G3DSA:3.40.1350.10 79 210 1.5E-34 T 13-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 THITH_06405 f08dafdb0ec8fd166390137557ea42e4 277 Pfam PF03477 ATP cone domain 2 62 2.6E-7 T 13-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 THITH_06405 f08dafdb0ec8fd166390137557ea42e4 277 Pfam PF04471 Restriction endonuclease 84 188 2.0E-6 T 13-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 THITH_06405 f08dafdb0ec8fd166390137557ea42e4 277 SUPERFAMILY SSF52980 83 195 1.72E-22 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_06110 a1a9b38a43064ed85d48f1b95b69f77c 440 SUPERFAMILY SSF51621 9 440 1.26E-150 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 THITH_06110 a1a9b38a43064ed85d48f1b95b69f77c 440 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 262 440 3.4E-88 T 13-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 THITH_06110 a1a9b38a43064ed85d48f1b95b69f77c 440 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 15 261 5.1E-109 T 13-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 THITH_06110 a1a9b38a43064ed85d48f1b95b69f77c 440 Gene3D G3DSA:3.20.20.60 6 423 1.1E-177 T 13-10-2018 THITH_06110 a1a9b38a43064ed85d48f1b95b69f77c 440 ProSitePatterns PS00161 Isocitrate lyase signature. 199 204 - T 13-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 THITH_06110 a1a9b38a43064ed85d48f1b95b69f77c 440 Pfam PF00463 Isocitrate lyase family 262 440 1.4E-50 T 13-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 THITH_06110 a1a9b38a43064ed85d48f1b95b69f77c 440 Pfam PF00463 Isocitrate lyase family 18 261 8.3E-60 T 13-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 THITH_06110 a1a9b38a43064ed85d48f1b95b69f77c 440 PIRSF PIRSF001362 6 440 1.4E-217 T 13-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 THITH_04665 99d1489ad809c49a9be9ee098c7dbee5 82 Pfam PF12651 Ribbon-helix-helix domain 2 41 6.8E-8 T 13-10-2018 IPR038733 Predicted DNA-binding protein, ribbon-helix-helix domain THITH_14895 febbb7ed1b7c6870c6bd33478d596ee0 355 SUPERFAMILY SSF53067 193 353 3.96E-23 T 13-10-2018 THITH_14895 febbb7ed1b7c6870c6bd33478d596ee0 355 Pfam PF11104 Type IV pilus assembly protein PilM; 13 353 7.1E-126 T 13-10-2018 IPR005883 Type IV pilus assembly protein PilM THITH_14895 febbb7ed1b7c6870c6bd33478d596ee0 355 Gene3D G3DSA:3.30.420.40 189 317 2.2E-79 T 13-10-2018 THITH_14895 febbb7ed1b7c6870c6bd33478d596ee0 355 Gene3D G3DSA:3.30.420.40 12 351 2.2E-79 T 13-10-2018 THITH_14895 febbb7ed1b7c6870c6bd33478d596ee0 355 PIRSF PIRSF019169 1 354 1.3E-110 T 13-10-2018 IPR005883 Type IV pilus assembly protein PilM THITH_14895 febbb7ed1b7c6870c6bd33478d596ee0 355 SUPERFAMILY SSF53067 54 173 7.12E-11 T 13-10-2018 THITH_14895 febbb7ed1b7c6870c6bd33478d596ee0 355 Gene3D G3DSA:3.30.1490.300 87 146 2.2E-79 T 13-10-2018 THITH_14895 febbb7ed1b7c6870c6bd33478d596ee0 355 TIGRFAM TIGR01175 pilM: type IV pilus assembly protein PilM 8 353 6.3E-102 T 13-10-2018 IPR005883 Type IV pilus assembly protein PilM THITH_14895 febbb7ed1b7c6870c6bd33478d596ee0 355 SMART SM00842 11 178 0.0073 T 13-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 THITH_09480 72e5820035f306ccbdd9ee4855c11991 492 SUPERFAMILY SSF50249 2 142 1.15E-40 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_09480 72e5820035f306ccbdd9ee4855c11991 492 Pfam PF00152 tRNA synthetases class II (D, K and N) 149 488 1.7E-81 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_09480 72e5820035f306ccbdd9ee4855c11991 492 Gene3D G3DSA:2.40.50.140 3 141 1.5E-39 T 13-10-2018 THITH_09480 72e5820035f306ccbdd9ee4855c11991 492 Pfam PF01336 OB-fold nucleic acid binding domain 56 133 3.8E-15 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 THITH_09480 72e5820035f306ccbdd9ee4855c11991 492 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 4 491 2.9E-200 T 13-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THITH_09480 72e5820035f306ccbdd9ee4855c11991 492 Gene3D G3DSA:3.30.930.10 145 492 1.3E-131 T 13-10-2018 THITH_09480 72e5820035f306ccbdd9ee4855c11991 492 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 9 491 43.7 T 13-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THITH_09480 72e5820035f306ccbdd9ee4855c11991 492 PRINTS PR00982 Lysyl-tRNA synthetase signature 202 218 2.2E-37 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THITH_09480 72e5820035f306ccbdd9ee4855c11991 492 PRINTS PR00982 Lysyl-tRNA synthetase signature 373 389 2.2E-37 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THITH_09480 72e5820035f306ccbdd9ee4855c11991 492 PRINTS PR00982 Lysyl-tRNA synthetase signature 231 244 2.2E-37 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THITH_09480 72e5820035f306ccbdd9ee4855c11991 492 PRINTS PR00982 Lysyl-tRNA synthetase signature 186 196 2.2E-37 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THITH_09480 72e5820035f306ccbdd9ee4855c11991 492 PRINTS PR00982 Lysyl-tRNA synthetase signature 249 266 2.2E-37 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THITH_09480 72e5820035f306ccbdd9ee4855c11991 492 SUPERFAMILY SSF55681 149 489 1.59E-120 T 13-10-2018 THITH_11845 e951cc2516766559ab5572ccbdd01a13 424 ProSitePatterns PS00550 Hemerythrin family signature. 350 373 - T 13-10-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 THITH_11845 e951cc2516766559ab5572ccbdd01a13 424 Gene3D G3DSA:1.20.120.50 293 423 7.3E-25 T 13-10-2018 IPR035938 Hemerythrin-like superfamily THITH_11845 e951cc2516766559ab5572ccbdd01a13 424 SUPERFAMILY SSF47188 295 419 2.88E-24 T 13-10-2018 IPR035938 Hemerythrin-like superfamily THITH_11845 e951cc2516766559ab5572ccbdd01a13 424 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 296 418 2.1E-26 T 13-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 THITH_11845 e951cc2516766559ab5572ccbdd01a13 424 SMART SM00267 105 273 1.8E-55 T 13-10-2018 IPR000160 GGDEF domain THITH_11845 e951cc2516766559ab5572ccbdd01a13 424 SUPERFAMILY SSF55073 121 272 2.12E-43 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_11845 e951cc2516766559ab5572ccbdd01a13 424 Pfam PF01814 Hemerythrin HHE cation binding domain 307 420 1.0E-12 T 13-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 THITH_11845 e951cc2516766559ab5572ccbdd01a13 424 Pfam PF00990 Diguanylate cyclase, GGDEF domain 118 269 1.1E-38 T 13-10-2018 IPR000160 GGDEF domain THITH_11845 e951cc2516766559ab5572ccbdd01a13 424 Gene3D G3DSA:3.30.70.270 102 273 1.0E-51 T 13-10-2018 THITH_11845 e951cc2516766559ab5572ccbdd01a13 424 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 112 272 2.8E-47 T 13-10-2018 IPR000160 GGDEF domain THITH_05355 dfd4e086a22b323d5dec3b671dc01712 184 Gene3D G3DSA:3.90.79.10 10 181 4.8E-55 T 13-10-2018 THITH_05355 dfd4e086a22b323d5dec3b671dc01712 184 SUPERFAMILY SSF55811 13 181 1.62E-49 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 THITH_05355 dfd4e086a22b323d5dec3b671dc01712 184 Pfam PF00293 NUDIX domain 48 162 2.2E-17 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 THITH_05355 dfd4e086a22b323d5dec3b671dc01712 184 PRINTS PR00502 NUDIX hydrolase family signature 91 106 8.4E-6 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 THITH_05355 dfd4e086a22b323d5dec3b671dc01712 184 PRINTS PR00502 NUDIX hydrolase family signature 77 91 8.4E-6 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 THITH_05355 dfd4e086a22b323d5dec3b671dc01712 184 ProSitePatterns PS00893 Nudix box signature. 82 103 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THITH_08515 678697542853933084db8fc0588cc1cd 248 Pfam PF17131 Outer membrane lipoprotein-sorting protein 71 242 1.1E-40 T 13-10-2018 IPR033399 Putative outer membrane lipoprotein-sorting protein THITH_08515 678697542853933084db8fc0588cc1cd 248 Gene3D G3DSA:2.50.20.10 23 243 1.0E-43 T 13-10-2018 THITH_13055 fe0d6124e6248dee80e0db0b627d423f 263 SUPERFAMILY SSF55347 123 232 6.54E-37 T 13-10-2018 THITH_13055 fe0d6124e6248dee80e0db0b627d423f 263 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 2 261 35.636 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THITH_13055 fe0d6124e6248dee80e0db0b627d423f 263 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 146 163 - T 13-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THITH_13055 fe0d6124e6248dee80e0db0b627d423f 263 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 124 260 1.1E-43 T 13-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THITH_13055 fe0d6124e6248dee80e0db0b627d423f 263 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 121 1.3E-35 T 13-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THITH_13055 fe0d6124e6248dee80e0db0b627d423f 263 Gene3D G3DSA:3.30.360.10 123 230 2.7E-99 T 13-10-2018 THITH_13055 fe0d6124e6248dee80e0db0b627d423f 263 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 2 261 6.7E-93 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THITH_13055 fe0d6124e6248dee80e0db0b627d423f 263 PIRSF PIRSF000161 1 263 1.6E-87 T 13-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THITH_13055 fe0d6124e6248dee80e0db0b627d423f 263 Gene3D G3DSA:3.40.50.720 4 260 2.7E-99 T 13-10-2018 THITH_13055 fe0d6124e6248dee80e0db0b627d423f 263 SUPERFAMILY SSF51735 1 262 5.22E-47 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_16125 97f878931f8b1b27564d800646122b08 1051 SUPERFAMILY SSF82693 136 324 3.4E-22 T 13-10-2018 THITH_16125 97f878931f8b1b27564d800646122b08 1051 SUPERFAMILY SSF82866 291 488 1.29E-47 T 13-10-2018 THITH_16125 97f878931f8b1b27564d800646122b08 1051 Gene3D G3DSA:3.30.70.1430 556 656 0.0 T 13-10-2018 THITH_16125 97f878931f8b1b27564d800646122b08 1051 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 5.3E-74 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_16125 97f878931f8b1b27564d800646122b08 1051 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 5.3E-74 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_16125 97f878931f8b1b27564d800646122b08 1051 PRINTS PR00702 Acriflavin resistance protein family signature 612 626 5.3E-74 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_16125 97f878931f8b1b27564d800646122b08 1051 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 5.3E-74 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_16125 97f878931f8b1b27564d800646122b08 1051 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 5.3E-74 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_16125 97f878931f8b1b27564d800646122b08 1051 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 5.3E-74 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_16125 97f878931f8b1b27564d800646122b08 1051 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 5.3E-74 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_16125 97f878931f8b1b27564d800646122b08 1051 PRINTS PR00702 Acriflavin resistance protein family signature 541 558 5.3E-74 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_16125 97f878931f8b1b27564d800646122b08 1051 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 5.3E-74 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_16125 97f878931f8b1b27564d800646122b08 1051 SUPERFAMILY SSF82714 182 266 2.49E-17 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_16125 97f878931f8b1b27564d800646122b08 1051 Gene3D G3DSA:3.30.70.1320 134 326 0.0 T 13-10-2018 THITH_16125 97f878931f8b1b27564d800646122b08 1051 Gene3D G3DSA:1.20.1640.10 10 501 0.0 T 13-10-2018 THITH_16125 97f878931f8b1b27564d800646122b08 1051 Pfam PF00873 AcrB/AcrD/AcrF family 5 1011 0.0 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_16125 97f878931f8b1b27564d800646122b08 1051 Gene3D G3DSA:3.30.70.1430 40 802 0.0 T 13-10-2018 THITH_16125 97f878931f8b1b27564d800646122b08 1051 Gene3D G3DSA:3.30.2090.10 706 794 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_16125 97f878931f8b1b27564d800646122b08 1051 SUPERFAMILY SSF82693 40 134 7.85E-28 T 13-10-2018 THITH_16125 97f878931f8b1b27564d800646122b08 1051 Gene3D G3DSA:1.20.1640.10 502 1008 0.0 T 13-10-2018 THITH_16125 97f878931f8b1b27564d800646122b08 1051 SUPERFAMILY SSF82866 790 1016 2.09E-50 T 13-10-2018 THITH_16125 97f878931f8b1b27564d800646122b08 1051 Gene3D G3DSA:3.30.70.1440 657 851 0.0 T 13-10-2018 THITH_16125 97f878931f8b1b27564d800646122b08 1051 SUPERFAMILY SSF82714 707 790 1.44E-19 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_16125 97f878931f8b1b27564d800646122b08 1051 SUPERFAMILY SSF82693 554 655 4.13E-19 T 13-10-2018 THITH_16125 97f878931f8b1b27564d800646122b08 1051 Gene3D G3DSA:3.30.2090.10 178 269 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_00490 60d89750a6d435ab0b531a1e32a513e5 156 PIRSF PIRSF010312 2 156 2.5E-39 T 13-10-2018 IPR016568 Sulphur oxidation, SoxY THITH_00490 60d89750a6d435ab0b531a1e32a513e5 156 TIGRFAM TIGR04488 SoxY_true_GGCGG: thiosulfate oxidation carrier protein SoxY 5 156 2.7E-45 T 13-10-2018 IPR016568 Sulphur oxidation, SoxY THITH_00490 60d89750a6d435ab0b531a1e32a513e5 156 Pfam PF13501 Sulfur oxidation protein SoxY 52 154 1.6E-29 T 13-10-2018 IPR032711 Ig-like SoxY domain THITH_00490 60d89750a6d435ab0b531a1e32a513e5 156 Gene3D G3DSA:2.60.40.2470 34 156 5.2E-38 T 13-10-2018 IPR038162 Ig-like SoxY domain superfamily THITH_04990 2c233470ba1f0bf79890a149ec195679 105 SUPERFAMILY SSF81301 5 101 1.15E-20 T 13-10-2018 THITH_04990 2c233470ba1f0bf79890a149ec195679 105 Gene3D G3DSA:3.30.460.10 7 99 1.1E-20 T 13-10-2018 THITH_04990 2c233470ba1f0bf79890a149ec195679 105 Pfam PF01909 Nucleotidyltransferase domain 16 88 1.8E-12 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THITH_14840 169cbec091f6fed40064f147256bdac4 104 Pfam PF01722 BolA-like protein 11 84 2.7E-32 T 13-10-2018 IPR002634 BolA protein THITH_14840 169cbec091f6fed40064f147256bdac4 104 PIRSF PIRSF003113 1 100 4.7E-38 T 13-10-2018 IPR002634 BolA protein THITH_14840 169cbec091f6fed40064f147256bdac4 104 Gene3D G3DSA:3.30.300.90 1 89 8.9E-36 T 13-10-2018 THITH_14840 169cbec091f6fed40064f147256bdac4 104 SUPERFAMILY SSF82657 2 87 3.27E-31 T 13-10-2018 IPR036065 BolA-like superfamily THITH_00330 5828e72daf5770c130fc3939169c6635 131 Pfam PF01850 PIN domain 4 122 1.2E-9 T 13-10-2018 IPR002716 PIN domain THITH_00330 5828e72daf5770c130fc3939169c6635 131 Gene3D G3DSA:3.40.50.1010 1 126 4.9E-25 T 13-10-2018 THITH_00330 5828e72daf5770c130fc3939169c6635 131 SUPERFAMILY SSF88723 3 126 5.05E-16 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_12735 a61ed2f57ae44fa025812011078d1e4f 242 SMART SM00849 9 221 0.0058 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_12735 a61ed2f57ae44fa025812011078d1e4f 242 Gene3D G3DSA:3.60.15.10 13 234 1.2E-30 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_12735 a61ed2f57ae44fa025812011078d1e4f 242 SUPERFAMILY SSF56281 12 240 1.54E-27 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_10800 b71aeb8544634cc72029439b92fbee6b 469 Gene3D G3DSA:3.30.499.20 5 287 4.0E-101 T 13-10-2018 THITH_10800 b71aeb8544634cc72029439b92fbee6b 469 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 4 463 3.7E-231 T 13-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 THITH_10800 b71aeb8544634cc72029439b92fbee6b 469 SUPERFAMILY SSF53732 2 467 5.89E-165 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 THITH_10800 b71aeb8544634cc72029439b92fbee6b 469 Pfam PF00330 Aconitase family (aconitate hydratase) 8 459 1.2E-157 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_10800 b71aeb8544634cc72029439b92fbee6b 469 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 468 59.89 T 13-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 THITH_10800 b71aeb8544634cc72029439b92fbee6b 469 Gene3D G3DSA:3.30.499.10 328 469 1.0E-47 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 THITH_10800 b71aeb8544634cc72029439b92fbee6b 469 PRINTS PR00415 Aconitase family signature 196 209 6.4E-50 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_10800 b71aeb8544634cc72029439b92fbee6b 469 PRINTS PR00415 Aconitase family signature 120 133 6.4E-50 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_10800 b71aeb8544634cc72029439b92fbee6b 469 PRINTS PR00415 Aconitase family signature 344 355 6.4E-50 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_10800 b71aeb8544634cc72029439b92fbee6b 469 PRINTS PR00415 Aconitase family signature 401 414 6.4E-50 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_10800 b71aeb8544634cc72029439b92fbee6b 469 PRINTS PR00415 Aconitase family signature 109 117 6.4E-50 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_10800 b71aeb8544634cc72029439b92fbee6b 469 PRINTS PR00415 Aconitase family signature 83 96 6.4E-50 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_10800 b71aeb8544634cc72029439b92fbee6b 469 PRINTS PR00415 Aconitase family signature 287 301 6.4E-50 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_10800 b71aeb8544634cc72029439b92fbee6b 469 PRINTS PR00415 Aconitase family signature 210 223 6.4E-50 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_10800 b71aeb8544634cc72029439b92fbee6b 469 PRINTS PR00415 Aconitase family signature 134 149 6.4E-50 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_10800 b71aeb8544634cc72029439b92fbee6b 469 ProSitePatterns PS01244 Aconitase family signature 2. 401 414 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 THITH_02500 b302ac69ee763f178c02c5f856cf3597 298 Gene3D G3DSA:3.90.1280.10 229 288 2.9E-20 T 13-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 THITH_02500 b302ac69ee763f178c02c5f856cf3597 298 Gene3D G3DSA:3.55.30.10 1 174 3.6E-58 T 13-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 THITH_02500 b302ac69ee763f178c02c5f856cf3597 298 SUPERFAMILY SSF118352 229 286 7.06E-18 T 13-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 THITH_02500 b302ac69ee763f178c02c5f856cf3597 298 Hamap MF_00117 33 kDa chaperonin [hslO]. 5 287 28.79 T 13-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 THITH_02500 b302ac69ee763f178c02c5f856cf3597 298 PIRSF PIRSF005261 1 288 1.1E-73 T 13-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 THITH_02500 b302ac69ee763f178c02c5f856cf3597 298 Gene3D G3DSA:1.10.287.480 182 228 3.2E-13 T 13-10-2018 IPR023212 Heat shock protein Hsp33, helix hairpin bin domain superfamily THITH_02500 b302ac69ee763f178c02c5f856cf3597 298 SUPERFAMILY SSF64397 6 235 5.23E-63 T 13-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 THITH_02500 b302ac69ee763f178c02c5f856cf3597 298 Pfam PF01430 Hsp33 protein 6 276 5.2E-80 T 13-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 THITH_00610 31f105c1791c9ed3399f3a99246dae26 271 SMART SM01232 131 223 7.2E-48 T 13-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 THITH_00610 31f105c1791c9ed3399f3a99246dae26 271 SUPERFAMILY SSF81624 2 136 1.31E-39 T 13-10-2018 IPR035937 MutM-like, N-terminal THITH_00610 31f105c1791c9ed3399f3a99246dae26 271 Pfam PF06827 Zinc finger found in FPG and IleRS 243 270 9.2E-7 T 13-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 THITH_00610 31f105c1791c9ed3399f3a99246dae26 271 Gene3D G3DSA:1.10.8.50 133 271 2.0E-46 T 13-10-2018 THITH_00610 31f105c1791c9ed3399f3a99246dae26 271 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 270 4.0E-85 T 13-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 THITH_00610 31f105c1791c9ed3399f3a99246dae26 271 Gene3D G3DSA:3.20.190.10 2 127 2.5E-35 T 13-10-2018 IPR035937 MutM-like, N-terminal THITH_00610 31f105c1791c9ed3399f3a99246dae26 271 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 271 42.873 T 13-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 THITH_00610 31f105c1791c9ed3399f3a99246dae26 271 SMART SM00898 2 116 1.3E-50 T 13-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 THITH_00610 31f105c1791c9ed3399f3a99246dae26 271 SUPERFAMILY SSF57716 219 270 3.99E-16 T 13-10-2018 THITH_00610 31f105c1791c9ed3399f3a99246dae26 271 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 114 6.6E-32 T 13-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 THITH_00610 31f105c1791c9ed3399f3a99246dae26 271 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 131 220 7.3E-24 T 13-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 THITH_00610 31f105c1791c9ed3399f3a99246dae26 271 SUPERFAMILY SSF46946 132 223 2.21E-29 T 13-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 THITH_00610 31f105c1791c9ed3399f3a99246dae26 271 ProSitePatterns PS01242 Zinc finger FPG-type signature. 246 270 - T 13-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 THITH_06785 24d6e0fb431e915e536e7f85622a8cf7 151 ProDom PD008308 HUPJ HYDROGENASE EXPRESSION/FORMATION HYDROGENASE-2 HYBE COMPONENT OPERON ELECTRON METAL-BINDING IRON 1 103 2.0E-17 T 13-10-2018 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE THITH_06785 24d6e0fb431e915e536e7f85622a8cf7 151 TIGRFAM TIGR03993 hydrog_HybE: [NiFe] hydrogenase assembly chaperone, HybE family 1 140 2.9E-35 T 13-10-2018 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE THITH_06785 24d6e0fb431e915e536e7f85622a8cf7 151 Gene3D G3DSA:3.30.1460.40 1 105 6.7E-30 T 13-10-2018 IPR038530 [NiFe]-hydrogenase assembly, chaperone, HybE superfamily THITH_06785 24d6e0fb431e915e536e7f85622a8cf7 151 Pfam PF11939 [NiFe]-hydrogenase assembly, chaperone, HybE 1 141 2.9E-38 T 13-10-2018 IPR023994 [NiFe]-hydrogenase assembly, chaperone, HybE THITH_12270 8e35be99182837055bbc5d7d706ef9cb 532 Gene3D G3DSA:3.40.50.300 346 520 8.1E-32 T 13-10-2018 THITH_12270 8e35be99182837055bbc5d7d706ef9cb 532 Pfam PF13671 AAA domain 350 500 5.2E-33 T 13-10-2018 THITH_12270 8e35be99182837055bbc5d7d706ef9cb 532 SUPERFAMILY SSF56112 10 317 4.08E-19 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily THITH_12270 8e35be99182837055bbc5d7d706ef9cb 532 Pfam PF01636 Phosphotransferase enzyme family 133 280 3.5E-6 T 13-10-2018 IPR002575 Aminoglycoside phosphotransferase THITH_12270 8e35be99182837055bbc5d7d706ef9cb 532 SUPERFAMILY SSF52540 346 508 2.35E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_06445 463e8d63e7fe37a8d53525a744cf5d62 488 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 217 272 - T 13-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_06445 463e8d63e7fe37a8d53525a744cf5d62 488 Gene3D G3DSA:1.20.210.10 16 486 7.7E-204 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_06445 463e8d63e7fe37a8d53525a744cf5d62 488 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 27 457 9.5E-117 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_06445 463e8d63e7fe37a8d53525a744cf5d62 488 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 23 484 1.3E-227 T 13-10-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 THITH_06445 463e8d63e7fe37a8d53525a744cf5d62 488 SUPERFAMILY SSF81442 23 481 3.79E-124 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_04550 288fd66691b97f6984dc90560b7f738e 131 Pfam PF01850 PIN domain 2 118 2.8E-11 T 13-10-2018 IPR002716 PIN domain THITH_04550 288fd66691b97f6984dc90560b7f738e 131 SUPERFAMILY SSF88723 1 123 7.01E-18 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_04550 288fd66691b97f6984dc90560b7f738e 131 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 128 10.393 T 13-10-2018 IPR022907 VapC family GO:0004540 THITH_04550 288fd66691b97f6984dc90560b7f738e 131 Gene3D G3DSA:3.40.50.1010 1 127 1.8E-24 T 13-10-2018 THITH_14240 0faf0f51c3499a0bb3182ca08f35ffbe 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 13-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14240 0faf0f51c3499a0bb3182ca08f35ffbe 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 4.0E-54 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 THITH_14240 0faf0f51c3499a0bb3182ca08f35ffbe 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.846 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 THITH_14240 0faf0f51c3499a0bb3182ca08f35ffbe 122 SMART SM01374 1 122 1.6E-84 T 13-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 THITH_14240 0faf0f51c3499a0bb3182ca08f35ffbe 122 SUPERFAMILY SSF50193 1 122 1.7E-50 T 13-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 THITH_14240 0faf0f51c3499a0bb3182ca08f35ffbe 122 Gene3D G3DSA:2.40.150.20 1 122 6.3E-54 T 13-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 THITH_14240 0faf0f51c3499a0bb3182ca08f35ffbe 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 7.0E-57 T 13-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 THITH_05120 5ed20bb4e810c55f7fb3ef254e43a06c 226 PIRSF PIRSF000498 1 208 3.1E-72 T 13-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THITH_05120 5ed20bb4e810c55f7fb3ef254e43a06c 226 SUPERFAMILY SSF63380 93 194 2.38E-32 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel THITH_05120 5ed20bb4e810c55f7fb3ef254e43a06c 226 Gene3D G3DSA:2.40.30.20 102 201 5.2E-34 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_05120 5ed20bb4e810c55f7fb3ef254e43a06c 226 Gene3D G3DSA:2.40.30.20 1 89 2.3E-27 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_05120 5ed20bb4e810c55f7fb3ef254e43a06c 226 Pfam PF00677 Lumazine binding domain 3 87 1.7E-21 T 13-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THITH_05120 5ed20bb4e810c55f7fb3ef254e43a06c 226 Pfam PF00677 Lumazine binding domain 100 184 2.4E-24 T 13-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THITH_05120 5ed20bb4e810c55f7fb3ef254e43a06c 226 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 198 1.3E-61 T 13-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THITH_05120 5ed20bb4e810c55f7fb3ef254e43a06c 226 SUPERFAMILY SSF63380 1 88 6.04E-25 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel THITH_07250 b45eaa3e8919bbf5eab175b476b700b9 288 PIRSF PIRSF000103 1 287 8.6E-63 T 13-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 THITH_07250 b45eaa3e8919bbf5eab175b476b700b9 288 SUPERFAMILY SSF48179 162 283 2.83E-31 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THITH_07250 b45eaa3e8919bbf5eab175b476b700b9 288 Gene3D G3DSA:3.40.50.720 2 161 5.5E-46 T 13-10-2018 THITH_07250 b45eaa3e8919bbf5eab175b476b700b9 288 SUPERFAMILY SSF51735 3 162 5.29E-41 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_07250 b45eaa3e8919bbf5eab175b476b700b9 288 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 164 282 1.5E-28 T 13-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 THITH_07250 b45eaa3e8919bbf5eab175b476b700b9 288 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 5 18 - T 13-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 THITH_07250 b45eaa3e8919bbf5eab175b476b700b9 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 160 6.2E-43 T 13-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 THITH_07250 b45eaa3e8919bbf5eab175b476b700b9 288 Gene3D G3DSA:1.10.1040.10 162 285 3.9E-31 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THITH_01410 76afcc847a3b87c0881f3708bdc4bb1c 159 SUPERFAMILY SSF54862 4 99 5.35E-20 T 13-10-2018 THITH_01410 76afcc847a3b87c0881f3708bdc4bb1c 159 Gene3D G3DSA:3.30.70.20 2 62 6.3E-23 T 13-10-2018 THITH_01410 76afcc847a3b87c0881f3708bdc4bb1c 159 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 42 53 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_01410 76afcc847a3b87c0881f3708bdc4bb1c 159 Pfam PF13187 4Fe-4S dicluster domain 9 57 2.7E-10 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_01410 76afcc847a3b87c0881f3708bdc4bb1c 159 Pfam PF12139 Adenosine-5'-phosphosulfate reductase beta subunit 59 142 1.2E-36 T 13-10-2018 IPR022738 Adenylylsulphate reductase, beta subunit, C-terminal THITH_01410 76afcc847a3b87c0881f3708bdc4bb1c 159 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_01410 76afcc847a3b87c0881f3708bdc4bb1c 159 Gene3D G3DSA:3.30.720.40 63 143 2.1E-18 T 13-10-2018 IPR038465 APS reductase, beta subunit, C-terminal domain superfamily THITH_01410 76afcc847a3b87c0881f3708bdc4bb1c 159 TIGRFAM TIGR02060 aprB: adenylylsulfate reductase, beta subunit 1 132 1.1E-61 T 13-10-2018 IPR011802 Adenylylsulphate reductase, beta subunit THITH_00415 8a3345ca43dbf3acc891d160fd858133 444 SMART SM00984 320 429 4.8E-43 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THITH_00415 8a3345ca43dbf3acc891d160fd858133 444 SUPERFAMILY SSF51735 1 193 9.11E-58 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_00415 8a3345ca43dbf3acc891d160fd858133 444 SUPERFAMILY SSF48179 204 298 1.0E-32 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THITH_00415 8a3345ca43dbf3acc891d160fd858133 444 Gene3D G3DSA:1.20.5.100 203 234 6.8E-19 T 13-10-2018 THITH_00415 8a3345ca43dbf3acc891d160fd858133 444 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 425 1.6E-136 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 THITH_00415 8a3345ca43dbf3acc891d160fd858133 444 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 320 428 3.5E-26 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THITH_00415 8a3345ca43dbf3acc891d160fd858133 444 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 205 296 3.4E-37 T 13-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THITH_00415 8a3345ca43dbf3acc891d160fd858133 444 PIRSF PIRSF500134 1 444 1.9E-186 T 13-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 THITH_00415 8a3345ca43dbf3acc891d160fd858133 444 PIRSF PIRSF000124 1 444 5.1E-148 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 THITH_00415 8a3345ca43dbf3acc891d160fd858133 444 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 186 2.8E-69 T 13-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THITH_00415 8a3345ca43dbf3acc891d160fd858133 444 Gene3D G3DSA:3.40.50.720 1 202 3.4E-83 T 13-10-2018 THITH_00415 8a3345ca43dbf3acc891d160fd858133 444 Gene3D G3DSA:3.40.50.720 235 444 4.1E-72 T 13-10-2018 THITH_00415 8a3345ca43dbf3acc891d160fd858133 444 SUPERFAMILY SSF52413 305 440 3.14E-34 T 13-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 THITH_14300 b568528ab477c973c067bafc235c50cc 396 SUPERFAMILY SSF50465 304 396 2.04E-36 T 13-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal THITH_14300 b568528ab477c973c067bafc235c50cc 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site THITH_14300 b568528ab477c973c067bafc235c50cc 396 Gene3D G3DSA:2.40.30.10 208 336 7.4E-54 T 13-10-2018 THITH_14300 b568528ab477c973c067bafc235c50cc 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 396 1.1E-229 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THITH_14300 b568528ab477c973c067bafc235c50cc 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 146 9.8E-15 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THITH_14300 b568528ab477c973c067bafc235c50cc 396 SUPERFAMILY SSF52540 6 221 1.59E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14300 b568528ab477c973c067bafc235c50cc 396 Gene3D G3DSA:3.40.50.300 1 205 5.2E-72 T 13-10-2018 THITH_14300 b568528ab477c973c067bafc235c50cc 396 SUPERFAMILY SSF50447 207 303 8.05E-32 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THITH_14300 b568528ab477c973c067bafc235c50cc 396 Gene3D G3DSA:2.40.30.10 340 395 2.4E-30 T 13-10-2018 THITH_14300 b568528ab477c973c067bafc235c50cc 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.345 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THITH_14300 b568528ab477c973c067bafc235c50cc 396 Pfam PF03144 Elongation factor Tu domain 2 227 296 1.8E-19 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THITH_14300 b568528ab477c973c067bafc235c50cc 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 5.5E-34 T 13-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal THITH_14300 b568528ab477c973c067bafc235c50cc 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.6E-59 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_14300 b568528ab477c973c067bafc235c50cc 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 9.6E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_14300 b568528ab477c973c067bafc235c50cc 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 9.6E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_14300 b568528ab477c973c067bafc235c50cc 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 9.6E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_14300 b568528ab477c973c067bafc235c50cc 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 9.6E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_14300 b568528ab477c973c067bafc235c50cc 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 9.6E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_13115 49bb14c384bd336664668863a28b7218 687 SUPERFAMILY SSF141868 442 677 6.8E-56 T 13-10-2018 IPR035919 EAL domain superfamily THITH_13115 49bb14c384bd336664668863a28b7218 687 SMART SM00052 435 680 2.0E-36 T 13-10-2018 IPR001633 EAL domain THITH_13115 49bb14c384bd336664668863a28b7218 687 Pfam PF00990 Diguanylate cyclase, GGDEF domain 263 419 2.1E-24 T 13-10-2018 IPR000160 GGDEF domain THITH_13115 49bb14c384bd336664668863a28b7218 687 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 261 421 4.3E-18 T 13-10-2018 IPR000160 GGDEF domain THITH_13115 49bb14c384bd336664668863a28b7218 687 SUPERFAMILY SSF52172 10 102 7.29E-6 T 13-10-2018 IPR011006 CheY-like superfamily THITH_13115 49bb14c384bd336664668863a28b7218 687 Pfam PF00563 EAL domain 442 675 1.5E-52 T 13-10-2018 IPR001633 EAL domain THITH_13115 49bb14c384bd336664668863a28b7218 687 SMART SM00091 141 207 3.5E-5 T 13-10-2018 IPR000014 PAS domain THITH_13115 49bb14c384bd336664668863a28b7218 687 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 137 238 7.2E-6 T 13-10-2018 IPR000014 PAS domain THITH_13115 49bb14c384bd336664668863a28b7218 687 Gene3D G3DSA:3.30.70.270 252 424 7.0E-34 T 13-10-2018 THITH_13115 49bb14c384bd336664668863a28b7218 687 SUPERFAMILY SSF55785 128 232 1.14E-11 T 13-10-2018 IPR035965 PAS domain superfamily THITH_13115 49bb14c384bd336664668863a28b7218 687 Gene3D G3DSA:3.20.20.450 425 684 2.0E-62 T 13-10-2018 IPR035919 EAL domain superfamily THITH_13115 49bb14c384bd336664668863a28b7218 687 Gene3D G3DSA:3.30.450.20 128 251 4.8E-12 T 13-10-2018 THITH_13115 49bb14c384bd336664668863a28b7218 687 SUPERFAMILY SSF55073 268 425 1.1E-28 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_13115 49bb14c384bd336664668863a28b7218 687 SMART SM00267 251 423 4.2E-22 T 13-10-2018 IPR000160 GGDEF domain THITH_13115 49bb14c384bd336664668863a28b7218 687 Pfam PF00989 PAS fold 142 208 1.5E-5 T 13-10-2018 IPR013767 PAS fold GO:0006355 THITH_01670 4c7abc1de334cd795f41b201dc03d6e1 856 Gene3D G3DSA:3.40.50.300 244 416 8.5E-14 T 13-10-2018 THITH_01670 4c7abc1de334cd795f41b201dc03d6e1 856 Pfam PF00271 Helicase conserved C-terminal domain 261 380 8.7E-6 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_01670 4c7abc1de334cd795f41b201dc03d6e1 856 Pfam PF00270 DEAD/DEAH box helicase 27 220 7.1E-6 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THITH_01670 4c7abc1de334cd795f41b201dc03d6e1 856 Gene3D G3DSA:3.40.50.300 14 232 1.3E-14 T 13-10-2018 THITH_01670 4c7abc1de334cd795f41b201dc03d6e1 856 SMART SM00490 289 380 8.2E-5 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_01670 4c7abc1de334cd795f41b201dc03d6e1 856 SUPERFAMILY SSF52540 37 394 1.08E-26 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01670 4c7abc1de334cd795f41b201dc03d6e1 856 TIGRFAM TIGR02621 cas3_GSU0051: CRISPR-associated helicase Cas3, subtype Dpsyc 9 847 5.0E-163 T 13-10-2018 IPR013444 Helicase Cas3, CRISPR-associated, Anaes-subtype THITH_01670 4c7abc1de334cd795f41b201dc03d6e1 856 Gene3D G3DSA:1.10.3210.30 664 851 2.0E-6 T 13-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily THITH_01670 4c7abc1de334cd795f41b201dc03d6e1 856 SMART SM00487 19 250 3.7E-5 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_02750 4911bff67714783184082e7c3f358f50 494 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 15 430 2.0E-154 T 13-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 THITH_02750 4911bff67714783184082e7c3f358f50 494 Pfam PF00575 S1 RNA binding domain 39 111 1.7E-6 T 13-10-2018 IPR003029 S1 domain GO:0003676 THITH_02750 4911bff67714783184082e7c3f358f50 494 Gene3D G3DSA:2.40.50.140 32 129 3.2E-28 T 13-10-2018 THITH_02750 4911bff67714783184082e7c3f358f50 494 SMART SM00316 38 124 1.2E-9 T 13-10-2018 IPR022967 RNA-binding domain, S1 THITH_02750 4911bff67714783184082e7c3f358f50 494 Gene3D G3DSA:3.40.1260.20 407 494 7.3E-7 T 13-10-2018 THITH_02750 4911bff67714783184082e7c3f358f50 494 Pfam PF10150 Ribonuclease E/G family 127 398 1.2E-98 T 13-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 THITH_02750 4911bff67714783184082e7c3f358f50 494 SUPERFAMILY SSF50249 40 129 6.22E-18 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_14030 9986c153375d5f8f1aa675f25925f1ca 156 Pfam PF02590 Predicted SPOUT methyltransferase 1 154 2.6E-47 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 THITH_14030 9986c153375d5f8f1aa675f25925f1ca 156 PIRSF PIRSF004505 1 155 3.1E-42 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 THITH_14030 9986c153375d5f8f1aa675f25925f1ca 156 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 2 155 2.8E-47 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 THITH_14030 9986c153375d5f8f1aa675f25925f1ca 156 SUPERFAMILY SSF75217 1 154 2.41E-47 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases THITH_14030 9986c153375d5f8f1aa675f25925f1ca 156 Gene3D G3DSA:3.40.1280.10 1 156 2.2E-47 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THITH_14030 9986c153375d5f8f1aa675f25925f1ca 156 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 1 155 27.853 T 13-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 THITH_04365 98f90410c6c6aef91759e84aec65d0c5 241 Hamap MF_00479 Ion-translocating oxidoreductase complex subunit G [rsxG]. 1 189 22.215 T 13-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 THITH_04365 98f90410c6c6aef91759e84aec65d0c5 241 TIGRFAM TIGR01947 rnfG: electron transport complex, RnfABCDGE type, G subunit 6 189 4.6E-52 T 13-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 THITH_04365 98f90410c6c6aef91759e84aec65d0c5 241 SMART SM00900 95 187 2.5E-33 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 THITH_04365 98f90410c6c6aef91759e84aec65d0c5 241 PIRSF PIRSF006091 1 199 5.9E-64 T 13-10-2018 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG GO:0005886|GO:0009055|GO:0022900 THITH_04365 98f90410c6c6aef91759e84aec65d0c5 241 Pfam PF04205 FMN-binding domain 95 184 2.8E-17 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 THITH_08380 30e08886102f40caaeaf240e7cc7a27b 261 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 6 256 31.167 T 13-10-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 THITH_08380 30e08886102f40caaeaf240e7cc7a27b 261 Pfam PF12697 Alpha/beta hydrolase family 13 249 6.8E-19 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_08380 30e08886102f40caaeaf240e7cc7a27b 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 82 95 4.7E-6 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_08380 30e08886102f40caaeaf240e7cc7a27b 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 4.7E-6 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_08380 30e08886102f40caaeaf240e7cc7a27b 261 PRINTS PR00111 Alpha/beta hydrolase fold signature 36 51 4.7E-6 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_08380 30e08886102f40caaeaf240e7cc7a27b 261 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 10 254 3.9E-71 T 13-10-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 THITH_08380 30e08886102f40caaeaf240e7cc7a27b 261 SUPERFAMILY SSF53474 8 253 4.78E-50 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_08380 30e08886102f40caaeaf240e7cc7a27b 261 Gene3D G3DSA:3.40.50.1820 4 256 1.8E-65 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_14665 3b3a9928ec9fae03b284408314291729 109 SUPERFAMILY SSF69754 1 99 4.45E-36 T 13-10-2018 IPR036567 Ribosome hibernation promotion factor-like THITH_14665 3b3a9928ec9fae03b284408314291729 109 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 98 6.7E-35 T 13-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 THITH_14665 3b3a9928ec9fae03b284408314291729 109 Gene3D G3DSA:3.30.160.100 1 106 4.1E-38 T 13-10-2018 IPR036567 Ribosome hibernation promotion factor-like THITH_14665 3b3a9928ec9fae03b284408314291729 109 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 93 6.7E-28 T 13-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 THITH_02115 091812f42c9517caa3633d4ce0cb438d 74 TIGRFAM TIGR02811 formate_TAT: formate dehydrogenase region TAT target 16 70 5.0E-17 T 13-10-2018 IPR014177 Putative formate dehydrogenase, TAT signal-containing THITH_02115 091812f42c9517caa3633d4ce0cb438d 74 PIRSF PIRSF036704 3 73 8.0E-13 T 13-10-2018 IPR014177 Putative formate dehydrogenase, TAT signal-containing THITH_02115 091812f42c9517caa3633d4ce0cb438d 74 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 17 43 3.8E-5 T 13-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THITH_08795 ba3195fea6a9e799bd150c35c3d798cd 381 SUPERFAMILY SSF111369 53 298 2.48E-65 T 13-10-2018 THITH_08795 ba3195fea6a9e799bd150c35c3d798cd 381 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 41 372 8.0E-83 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THITH_08795 ba3195fea6a9e799bd150c35c3d798cd 381 Gene3D G3DSA:1.10.287.470 100 173 3.6E-99 T 13-10-2018 THITH_08795 ba3195fea6a9e799bd150c35c3d798cd 381 Gene3D G3DSA:2.40.50.100 65 208 3.6E-99 T 13-10-2018 THITH_08795 ba3195fea6a9e799bd150c35c3d798cd 381 Gene3D G3DSA:2.40.30.170 51 301 3.6E-99 T 13-10-2018 THITH_08795 ba3195fea6a9e799bd150c35c3d798cd 381 Gene3D G3DSA:2.40.420.20 302 370 3.6E-99 T 13-10-2018 THITH_08795 ba3195fea6a9e799bd150c35c3d798cd 381 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 51 291 1.9E-13 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THITH_12965 7605624cc8c47f59963a3491f8dcc7e2 426 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 167 182 - T 13-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12965 7605624cc8c47f59963a3491f8dcc7e2 426 SUPERFAMILY SSF140490 325 421 6.28E-37 T 13-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12965 7605624cc8c47f59963a3491f8dcc7e2 426 Gene3D G3DSA:3.10.20.600 232 326 7.2E-35 T 13-10-2018 THITH_12965 7605624cc8c47f59963a3491f8dcc7e2 426 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 331 412 4.0E-31 T 13-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12965 7605624cc8c47f59963a3491f8dcc7e2 426 SUPERFAMILY SSF142019 4 239 1.16E-82 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12965 7605624cc8c47f59963a3491f8dcc7e2 426 Gene3D G3DSA:3.40.50.11540 52 231 4.6E-76 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12965 7605624cc8c47f59963a3491f8dcc7e2 426 Pfam PF10531 SLBB domain 243 291 1.9E-16 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12965 7605624cc8c47f59963a3491f8dcc7e2 426 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 342 353 - T 13-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12965 7605624cc8c47f59963a3491f8dcc7e2 426 SUPERFAMILY SSF142984 241 324 3.53E-27 T 13-10-2018 THITH_12965 7605624cc8c47f59963a3491f8dcc7e2 426 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 47 219 1.6E-42 T 13-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12965 7605624cc8c47f59963a3491f8dcc7e2 426 SMART SM00928 329 374 1.8E-26 T 13-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12965 7605624cc8c47f59963a3491f8dcc7e2 426 Gene3D G3DSA:1.20.1440.230 327 425 8.9E-35 T 13-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12965 7605624cc8c47f59963a3491f8dcc7e2 426 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 12 415 1.0E-197 T 13-10-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_08030 3945f9a0af92c5f2467dc7adaf015d0a 327 Gene3D G3DSA:3.40.50.720 142 260 3.4E-10 T 13-10-2018 THITH_08030 3945f9a0af92c5f2467dc7adaf015d0a 327 SUPERFAMILY SSF51735 124 265 1.73E-18 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_08030 3945f9a0af92c5f2467dc7adaf015d0a 327 Gene3D G3DSA:3.90.180.10 1 141 1.8E-10 T 13-10-2018 THITH_08030 3945f9a0af92c5f2467dc7adaf015d0a 327 SUPERFAMILY SSF50129 4 158 1.67E-16 T 13-10-2018 IPR011032 GroES-like superfamily THITH_08030 3945f9a0af92c5f2467dc7adaf015d0a 327 Pfam PF13450 NAD(P)-binding Rossmann-like domain 154 186 1.0E-4 T 13-10-2018 THITH_10875 85f2979d6341b81320a3164ec0653a91 421 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 196 206 - T 13-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 THITH_10875 85f2979d6341b81320a3164ec0653a91 421 SUPERFAMILY SSF53448 5 340 6.57E-69 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_10875 85f2979d6341b81320a3164ec0653a91 421 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 3 403 42.048 T 13-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 THITH_10875 85f2979d6341b81320a3164ec0653a91 421 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 98 106 - T 13-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 THITH_10875 85f2979d6341b81320a3164ec0653a91 421 Gene3D G3DSA:3.90.550.10 1 290 3.9E-81 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_10875 85f2979d6341b81320a3164ec0653a91 421 Gene3D G3DSA:2.160.10.10 291 404 3.9E-25 T 13-10-2018 THITH_10875 85f2979d6341b81320a3164ec0653a91 421 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 12 31 - T 13-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 THITH_10875 85f2979d6341b81320a3164ec0653a91 421 SUPERFAMILY SSF51161 304 394 2.36E-13 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily THITH_10875 85f2979d6341b81320a3164ec0653a91 421 Pfam PF00483 Nucleotidyl transferase 8 275 2.6E-57 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 THITH_03505 06540f1aa23260b164351bda8abf0d65 294 SUPERFAMILY SSF117892 50 187 9.68E-30 T 13-10-2018 IPR036013 Band 7/SPFH domain superfamily THITH_03505 06540f1aa23260b164351bda8abf0d65 294 SMART SM00244 18 181 2.5E-34 T 13-10-2018 IPR001107 Band 7 domain THITH_03505 06540f1aa23260b164351bda8abf0d65 294 Pfam PF01145 SPFH domain / Band 7 family 22 197 8.9E-29 T 13-10-2018 IPR001107 Band 7 domain THITH_03505 06540f1aa23260b164351bda8abf0d65 294 Gene3D G3DSA:3.30.479.30 47 183 4.3E-22 T 13-10-2018 THITH_03505 06540f1aa23260b164351bda8abf0d65 294 PIRSF PIRSF005651 1 290 6.9E-93 T 13-10-2018 IPR010200 HflC GO:0016021|GO:0052547 THITH_03505 06540f1aa23260b164351bda8abf0d65 294 TIGRFAM TIGR01932 hflC: HflC protein 140 280 1.5E-43 T 13-10-2018 IPR010200 HflC GO:0016021|GO:0052547 THITH_13950 40afcdc408417461b88b8a242a8d6842 566 ProSitePatterns PS00211 ABC transporters family signature. 483 497 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_13950 40afcdc408417461b88b8a242a8d6842 566 Gene3D G3DSA:3.40.50.300 348 566 2.5E-59 T 13-10-2018 THITH_13950 40afcdc408417461b88b8a242a8d6842 566 Pfam PF00664 ABC transporter transmembrane region 72 279 1.8E-14 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 THITH_13950 40afcdc408417461b88b8a242a8d6842 566 SMART SM00382 380 559 4.4E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_13950 40afcdc408417461b88b8a242a8d6842 566 SUPERFAMILY SSF90123 15 332 3.14E-42 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THITH_13950 40afcdc408417461b88b8a242a8d6842 566 Gene3D G3DSA:1.20.1560.10 3 336 7.5E-35 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THITH_13950 40afcdc408417461b88b8a242a8d6842 566 Pfam PF00005 ABC transporter 371 511 6.5E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_13950 40afcdc408417461b88b8a242a8d6842 566 SUPERFAMILY SSF52540 348 562 5.88E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13950 40afcdc408417461b88b8a242a8d6842 566 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 26 555 2.5E-146 T 13-10-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 THITH_09405 71d3cf38f121b9dbec0d68ff2e90a13a 107 SUPERFAMILY SSF54862 1 97 9.08E-24 T 13-10-2018 THITH_09405 71d3cf38f121b9dbec0d68ff2e90a13a 107 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.1E-17 T 13-10-2018 IPR000813 7Fe ferredoxin GO:0009055 THITH_09405 71d3cf38f121b9dbec0d68ff2e90a13a 107 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.1E-17 T 13-10-2018 IPR000813 7Fe ferredoxin GO:0009055 THITH_09405 71d3cf38f121b9dbec0d68ff2e90a13a 107 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.1E-17 T 13-10-2018 IPR000813 7Fe ferredoxin GO:0009055 THITH_09405 71d3cf38f121b9dbec0d68ff2e90a13a 107 Gene3D G3DSA:3.30.70.20 2 96 7.3E-32 T 13-10-2018 THITH_09405 71d3cf38f121b9dbec0d68ff2e90a13a 107 Pfam PF00037 4Fe-4S binding domain 34 55 2.6E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_09405 71d3cf38f121b9dbec0d68ff2e90a13a 107 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_09405 71d3cf38f121b9dbec0d68ff2e90a13a 107 Pfam PF11953 Domain of unknown function (DUF3470) 66 107 2.6E-23 T 13-10-2018 IPR022569 Ferredoxin, C-terminal THITH_11855 7554d5594a89d4e8a0e1e9013ff1f1bf 570 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 132 1.7E-22 T 13-10-2018 IPR000014 PAS domain THITH_11855 7554d5594a89d4e8a0e1e9013ff1f1bf 570 Pfam PF00563 EAL domain 314 549 8.2E-77 T 13-10-2018 IPR001633 EAL domain THITH_11855 7554d5594a89d4e8a0e1e9013ff1f1bf 570 Pfam PF13426 PAS domain 22 124 2.0E-17 T 13-10-2018 IPR000014 PAS domain THITH_11855 7554d5594a89d4e8a0e1e9013ff1f1bf 570 Gene3D G3DSA:3.30.70.270 135 310 4.8E-63 T 13-10-2018 THITH_11855 7554d5594a89d4e8a0e1e9013ff1f1bf 570 SMART SM00267 125 298 7.6E-73 T 13-10-2018 IPR000160 GGDEF domain THITH_11855 7554d5594a89d4e8a0e1e9013ff1f1bf 570 SMART SM00086 83 125 4.5E-4 T 13-10-2018 IPR001610 PAC motif THITH_11855 7554d5594a89d4e8a0e1e9013ff1f1bf 570 Gene3D G3DSA:3.30.450.20 7 134 1.8E-39 T 13-10-2018 THITH_11855 7554d5594a89d4e8a0e1e9013ff1f1bf 570 SUPERFAMILY SSF55785 16 123 1.74E-31 T 13-10-2018 IPR035965 PAS domain superfamily THITH_11855 7554d5594a89d4e8a0e1e9013ff1f1bf 570 SUPERFAMILY SSF141868 314 561 1.16E-91 T 13-10-2018 IPR035919 EAL domain superfamily THITH_11855 7554d5594a89d4e8a0e1e9013ff1f1bf 570 SMART SM00091 11 81 1.9E-8 T 13-10-2018 IPR000014 PAS domain THITH_11855 7554d5594a89d4e8a0e1e9013ff1f1bf 570 Gene3D G3DSA:3.20.20.450 311 567 2.5E-102 T 13-10-2018 IPR035919 EAL domain superfamily THITH_11855 7554d5594a89d4e8a0e1e9013ff1f1bf 570 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 132 296 2.4E-46 T 13-10-2018 IPR000160 GGDEF domain THITH_11855 7554d5594a89d4e8a0e1e9013ff1f1bf 570 SUPERFAMILY SSF55073 141 299 5.73E-51 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_11855 7554d5594a89d4e8a0e1e9013ff1f1bf 570 SMART SM00052 308 554 1.5E-117 T 13-10-2018 IPR001633 EAL domain THITH_11855 7554d5594a89d4e8a0e1e9013ff1f1bf 570 Pfam PF00990 Diguanylate cyclase, GGDEF domain 136 294 7.6E-51 T 13-10-2018 IPR000160 GGDEF domain THITH_00110 3159f1f11a90bf7af4b3de47c853bc90 210 Gene3D G3DSA:3.10.610.10 39 141 5.0E-13 T 13-10-2018 THITH_00110 3159f1f11a90bf7af4b3de47c853bc90 210 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 7 27 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_00110 3159f1f11a90bf7af4b3de47c853bc90 210 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 7 29 2.0E-8 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_00110 3159f1f11a90bf7af4b3de47c853bc90 210 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 29 1.7E-8 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_00110 3159f1f11a90bf7af4b3de47c853bc90 210 Pfam PF11612 Type II secretion system (T2SS), protein J 59 202 1.3E-24 T 13-10-2018 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 THITH_00110 3159f1f11a90bf7af4b3de47c853bc90 210 TIGRFAM TIGR01711 gspJ: type II secretion system protein J 7 203 4.4E-27 T 13-10-2018 IPR010055 Type II secretion system protein J GO:0008565|GO:0015627|GO:0015628 THITH_00110 3159f1f11a90bf7af4b3de47c853bc90 210 SUPERFAMILY SSF54523 49 208 2.98E-20 T 13-10-2018 THITH_16935 b118479215f11d2da52896d4a1894d91 723 SMART SM00471 61 173 1.4E-10 T 13-10-2018 IPR003607 HD/PDEase domain THITH_16935 b118479215f11d2da52896d4a1894d91 723 Gene3D G3DSA:3.30.460.10 213 345 8.7E-47 T 13-10-2018 THITH_16935 b118479215f11d2da52896d4a1894d91 723 Pfam PF04607 Region found in RelA / SpoT proteins 255 364 2.1E-35 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 THITH_16935 b118479215f11d2da52896d4a1894d91 723 SMART SM00954 255 365 6.9E-60 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 THITH_16935 b118479215f11d2da52896d4a1894d91 723 SUPERFAMILY SSF81301 201 412 1.26E-58 T 13-10-2018 THITH_16935 b118479215f11d2da52896d4a1894d91 723 Gene3D G3DSA:3.30.70.260 644 722 5.0E-16 T 13-10-2018 THITH_16935 b118479215f11d2da52896d4a1894d91 723 SUPERFAMILY SSF55021 647 721 6.87E-12 T 13-10-2018 THITH_16935 b118479215f11d2da52896d4a1894d91 723 Pfam PF13328 HD domain 47 195 2.8E-49 T 13-10-2018 IPR003607 HD/PDEase domain THITH_16935 b118479215f11d2da52896d4a1894d91 723 Pfam PF02824 TGS domain 408 467 2.4E-17 T 13-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 THITH_16935 b118479215f11d2da52896d4a1894d91 723 SUPERFAMILY SSF81271 395 467 1.05E-21 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 THITH_16935 b118479215f11d2da52896d4a1894d91 723 Gene3D G3DSA:3.10.20.30 401 474 3.0E-28 T 13-10-2018 IPR012675 Beta-grasp domain superfamily THITH_16935 b118479215f11d2da52896d4a1894d91 723 SUPERFAMILY SSF109604 26 210 4.13E-69 T 13-10-2018 THITH_16935 b118479215f11d2da52896d4a1894d91 723 Gene3D G3DSA:1.10.3210.10 19 210 3.6E-75 T 13-10-2018 THITH_16935 b118479215f11d2da52896d4a1894d91 723 Pfam PF13291 ACT domain 644 720 1.5E-18 T 13-10-2018 IPR002912 ACT domain THITH_16935 b118479215f11d2da52896d4a1894d91 723 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 46 720 9.5E-237 T 13-10-2018 IPR004811 RelA/SpoT family GO:0015969 THITH_10210 acc4c2c8251e8cb4b8b05d9d0ad262b8 577 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 51 157 1.2E-19 T 13-10-2018 IPR007831 General secretory system II, protein E, N-terminal THITH_10210 acc4c2c8251e8cb4b8b05d9d0ad262b8 577 Gene3D G3DSA:3.30.300.160 73 153 3.2E-17 T 13-10-2018 THITH_10210 acc4c2c8251e8cb4b8b05d9d0ad262b8 577 Pfam PF00437 Type II/IV secretion system protein 195 460 8.5E-84 T 13-10-2018 IPR001482 Type II/IV secretion system protein THITH_10210 acc4c2c8251e8cb4b8b05d9d0ad262b8 577 SUPERFAMILY SSF160246 16 152 5.75E-34 T 13-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily THITH_10210 acc4c2c8251e8cb4b8b05d9d0ad262b8 577 SUPERFAMILY SSF52540 172 570 9.53E-98 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_10210 acc4c2c8251e8cb4b8b05d9d0ad262b8 577 SMART SM00382 321 444 2.9E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_10210 acc4c2c8251e8cb4b8b05d9d0ad262b8 577 Gene3D G3DSA:3.40.50.300 294 576 1.5E-109 T 13-10-2018 THITH_10210 acc4c2c8251e8cb4b8b05d9d0ad262b8 577 Gene3D G3DSA:3.30.450.90 165 293 1.1E-44 T 13-10-2018 THITH_10210 acc4c2c8251e8cb4b8b05d9d0ad262b8 577 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 388 402 - T 13-10-2018 IPR001482 Type II/IV secretion system protein THITH_09795 2f6ff1cab96b25f65ff577bc9e41c2da 355 Gene3D G3DSA:3.30.420.10 131 297 4.5E-12 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_09795 2f6ff1cab96b25f65ff577bc9e41c2da 355 SUPERFAMILY SSF53098 136 303 3.79E-38 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_09795 2f6ff1cab96b25f65ff577bc9e41c2da 355 Pfam PF00665 Integrase core domain 136 251 1.6E-21 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 THITH_00920 d9a2276db3836afb5c4952e64b3aa07d 86 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 85 28.726 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_00920 d9a2276db3836afb5c4952e64b3aa07d 86 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 69 9.0E-15 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_00920 d9a2276db3836afb5c4952e64b3aa07d 86 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 82 7.7E-41 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_00920 d9a2276db3836afb5c4952e64b3aa07d 86 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 13-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_00920 d9a2276db3836afb5c4952e64b3aa07d 86 Pfam PF01016 Ribosomal L27 protein 2 82 6.6E-39 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_00920 d9a2276db3836afb5c4952e64b3aa07d 86 PRINTS PR00063 Ribosomal protein L27 signature 29 53 2.1E-36 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_00920 d9a2276db3836afb5c4952e64b3aa07d 86 PRINTS PR00063 Ribosomal protein L27 signature 4 28 2.1E-36 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_00920 d9a2276db3836afb5c4952e64b3aa07d 86 PRINTS PR00063 Ribosomal protein L27 signature 54 78 2.1E-36 T 13-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_00920 d9a2276db3836afb5c4952e64b3aa07d 86 Gene3D G3DSA:2.40.50.100 21 86 5.0E-30 T 13-10-2018 THITH_00920 d9a2276db3836afb5c4952e64b3aa07d 86 SUPERFAMILY SSF110324 2 81 1.29E-33 T 13-10-2018 THITH_07045 765fbc882b484abb70bc5480e5044e7f 365 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 15 361 1.7E-126 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THITH_07045 765fbc882b484abb70bc5480e5044e7f 365 Gene3D G3DSA:3.40.640.10 1 243 3.0E-99 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_07045 765fbc882b484abb70bc5480e5044e7f 365 Gene3D G3DSA:3.90.1150.10 245 363 2.8E-33 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_07045 765fbc882b484abb70bc5480e5044e7f 365 PIRSF PIRSF000390 1 365 1.9E-110 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THITH_07045 765fbc882b484abb70bc5480e5044e7f 365 SUPERFAMILY SSF53383 9 364 4.08E-116 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_14355 dc328801997ab2297d1239062a26412d 122 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 68 119 1.3E-17 T 13-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THITH_14355 dc328801997ab2297d1239062a26412d 122 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 69 97 - T 13-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THITH_14355 dc328801997ab2297d1239062a26412d 122 Gene3D G3DSA:1.20.5.1030 64 120 4.6E-15 T 13-10-2018 IPR038379 SecE superfamily THITH_14355 dc328801997ab2297d1239062a26412d 122 Hamap MF_00422 Protein translocase subunit SecE [secE]. 64 120 12.381 T 13-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THITH_14355 dc328801997ab2297d1239062a26412d 122 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 68 121 3.4E-16 T 13-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 THITH_14355 dc328801997ab2297d1239062a26412d 122 PRINTS PR01650 Bacterial translocase SecE signature 107 122 2.9E-21 T 13-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 THITH_14355 dc328801997ab2297d1239062a26412d 122 PRINTS PR01650 Bacterial translocase SecE signature 63 83 2.9E-21 T 13-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 THITH_14355 dc328801997ab2297d1239062a26412d 122 PRINTS PR01650 Bacterial translocase SecE signature 42 63 2.9E-21 T 13-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 THITH_14355 dc328801997ab2297d1239062a26412d 122 PRINTS PR01650 Bacterial translocase SecE signature 87 107 2.9E-21 T 13-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 THITH_04310 522f2f1fc6ebc47ace70dc155355eb77 351 Pfam PF01925 Sulfite exporter TauE/SafE 48 286 1.3E-24 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 THITH_10430 4090ba3f4ba7bfc08466bd22230f8c0c 394 SUPERFAMILY SSF55347 123 268 1.41E-58 T 13-10-2018 THITH_10430 4090ba3f4ba7bfc08466bd22230f8c0c 394 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 390 1.0E-151 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 THITH_10430 4090ba3f4ba7bfc08466bd22230f8c0c 394 PIRSF PIRSF006205 1 393 2.3E-146 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 THITH_10430 4090ba3f4ba7bfc08466bd22230f8c0c 394 SUPERFAMILY SSF69055 296 387 4.05E-31 T 13-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 THITH_10430 4090ba3f4ba7bfc08466bd22230f8c0c 394 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 1 386 45.779 T 13-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 THITH_10430 4090ba3f4ba7bfc08466bd22230f8c0c 394 Pfam PF13288 DXP reductoisomerase C-terminal domain 265 381 1.8E-41 T 13-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 THITH_10430 4090ba3f4ba7bfc08466bd22230f8c0c 394 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 1 129 2.4E-43 T 13-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 THITH_10430 4090ba3f4ba7bfc08466bd22230f8c0c 394 Gene3D G3DSA:3.40.50.720 1 147 4.0E-49 T 13-10-2018 THITH_10430 4090ba3f4ba7bfc08466bd22230f8c0c 394 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 143 233 1.1E-37 T 13-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 THITH_10430 4090ba3f4ba7bfc08466bd22230f8c0c 394 Gene3D G3DSA:1.10.1740.10 307 391 2.0E-29 T 13-10-2018 THITH_10430 4090ba3f4ba7bfc08466bd22230f8c0c 394 SUPERFAMILY SSF51735 1 147 4.44E-43 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_12020 8c34e4e2e4986d02c9a53cab2c72f343 648 SUPERFAMILY SSF54862 48 644 4.6E-16 T 13-10-2018 THITH_12020 8c34e4e2e4986d02c9a53cab2c72f343 648 Pfam PF13187 4Fe-4S dicluster domain 591 642 4.8E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_12020 8c34e4e2e4986d02c9a53cab2c72f343 648 Gene3D G3DSA:3.50.50.60 315 413 3.9E-20 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_12020 8c34e4e2e4986d02c9a53cab2c72f343 648 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 145 464 1.4E-23 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THITH_12020 8c34e4e2e4986d02c9a53cab2c72f343 648 SUPERFAMILY SSF51971 144 414 2.18E-49 T 13-10-2018 THITH_12020 8c34e4e2e4986d02c9a53cab2c72f343 648 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 33 132 1.6E-12 T 13-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 THITH_12020 8c34e4e2e4986d02c9a53cab2c72f343 648 Gene3D G3DSA:3.50.50.60 143 271 2.9E-30 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_12020 8c34e4e2e4986d02c9a53cab2c72f343 648 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 627 638 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_12020 8c34e4e2e4986d02c9a53cab2c72f343 648 Gene3D G3DSA:1.10.1060.10 2 142 1.2E-18 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_12020 8c34e4e2e4986d02c9a53cab2c72f343 648 PRINTS PR00419 Adrenodoxin reductase family signature 212 222 9.1E-18 T 13-10-2018 THITH_12020 8c34e4e2e4986d02c9a53cab2c72f343 648 PRINTS PR00419 Adrenodoxin reductase family signature 279 293 9.1E-18 T 13-10-2018 THITH_12020 8c34e4e2e4986d02c9a53cab2c72f343 648 PRINTS PR00419 Adrenodoxin reductase family signature 146 168 9.1E-18 T 13-10-2018 THITH_12020 8c34e4e2e4986d02c9a53cab2c72f343 648 PRINTS PR00419 Adrenodoxin reductase family signature 169 182 9.1E-18 T 13-10-2018 THITH_12020 8c34e4e2e4986d02c9a53cab2c72f343 648 Gene3D G3DSA:3.30.70.20 589 648 2.3E-9 T 13-10-2018 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 Pfam PF00072 Response regulator receiver domain 989 1099 1.3E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 SUPERFAMILY SSF55781 261 439 1.18E-20 T 13-10-2018 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 574 702 2.7E-11 T 13-10-2018 IPR000014 PAS domain THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 500 576 4.9E-9 T 13-10-2018 IPR000014 PAS domain THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 SMART SM00387 843 959 1.6E-37 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 Pfam PF00512 His Kinase A (phospho-acceptor) domain 734 797 3.1E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 Gene3D G3DSA:3.40.50.2300 983 1119 9.7E-43 T 13-10-2018 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 SMART SM00086 653 695 6.2E-7 T 13-10-2018 IPR001610 PAC motif THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 SMART SM00086 527 569 0.015 T 13-10-2018 IPR001610 PAC motif THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 Gene3D G3DSA:1.20.120.160 1144 1243 6.8E-16 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 SMART SM00448 987 1100 7.9E-37 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 SMART SM00065 292 449 3.5E-4 T 13-10-2018 IPR003018 GAF domain GO:0005515 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 Gene3D G3DSA:1.10.287.130 697 795 1.0E-25 T 13-10-2018 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 Pfam PF01627 Hpt domain 1157 1235 5.6E-8 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 Pfam PF13185 GAF domain 293 439 6.2E-8 T 13-10-2018 IPR003018 GAF domain GO:0005515 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 SMART SM00388 733 797 2.8E-20 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 Gene3D G3DSA:3.30.450.20 576 692 7.2E-21 T 13-10-2018 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 SUPERFAMILY SSF52172 985 1111 5.98E-39 T 13-10-2018 IPR011006 CheY-like superfamily THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 Gene3D G3DSA:2.10.70.100 524 570 1.9E-12 T 13-10-2018 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 Gene3D G3DSA:3.30.450.40 292 451 7.1E-19 T 13-10-2018 IPR029016 GAF-like domain superfamily THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 843 958 4.4E-28 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 Gene3D G3DSA:3.30.565.10 796 960 1.7E-50 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 SUPERFAMILY SSF55785 599 697 4.35E-17 T 13-10-2018 IPR035965 PAS domain superfamily THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 Pfam PF08447 PAS fold 476 563 3.0E-14 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 Pfam PF08447 PAS fold 604 688 6.2E-17 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 SUPERFAMILY SSF47384 718 798 5.69E-20 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 SUPERFAMILY SSF47226 1083 1236 1.57E-20 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 PRINTS PR00344 Bacterial sensor protein C-terminal signature 943 956 1.9E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 PRINTS PR00344 Bacterial sensor protein C-terminal signature 902 912 1.9E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 PRINTS PR00344 Bacterial sensor protein C-terminal signature 919 937 1.9E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 PRINTS PR00344 Bacterial sensor protein C-terminal signature 884 898 1.9E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 SUPERFAMILY SSF55874 786 956 6.16E-44 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 Gene3D G3DSA:3.30.450.20 452 521 1.1E-21 T 13-10-2018 THITH_12525 c7b3405e57dcb7c2e86537c8362462d6 1248 SUPERFAMILY SSF55785 443 567 3.7E-18 T 13-10-2018 IPR035965 PAS domain superfamily THITH_07410 233dc112253b614ed1036bcfbfe0c8fd 369 PIRSF PIRSF004869 1 322 1.5E-92 T 13-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted THITH_07410 233dc112253b614ed1036bcfbfe0c8fd 369 SUPERFAMILY SSF102114 53 324 3.4E-42 T 13-10-2018 THITH_07410 233dc112253b614ed1036bcfbfe0c8fd 369 Gene3D G3DSA:3.20.20.70 76 295 1.2E-34 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_07410 233dc112253b614ed1036bcfbfe0c8fd 369 Pfam PF04055 Radical SAM superfamily 89 242 2.9E-18 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THITH_07410 233dc112253b614ed1036bcfbfe0c8fd 369 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 14 362 9.0E-195 T 13-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme THITH_00250 778276e4bf3f940bcfa010c1b712460a 134 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 8 74 2.1E-22 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THITH_00250 778276e4bf3f940bcfa010c1b712460a 134 Pfam PF01467 Cytidylyltransferase-like 11 114 1.9E-23 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THITH_00250 778276e4bf3f940bcfa010c1b712460a 134 Gene3D G3DSA:3.40.50.620 7 133 4.8E-42 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_00250 778276e4bf3f940bcfa010c1b712460a 134 SUPERFAMILY SSF52374 8 132 1.74E-31 T 13-10-2018 THITH_00205 c7b26ca28f25683a82d12736f89d2207 74 Gene3D G3DSA:1.10.10.10 7 71 5.2E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_00205 c7b26ca28f25683a82d12736f89d2207 74 Pfam PF04255 Protein of unknown function (DUF433) 8 63 5.6E-25 T 13-10-2018 IPR007367 Protein of unknown function DUF433 THITH_00205 c7b26ca28f25683a82d12736f89d2207 74 SUPERFAMILY SSF46689 3 68 6.45E-22 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_17485 e7031054ec8281d50208145d96cc1336 354 Gene3D G3DSA:1.20.1690.10 82 186 2.2E-28 T 13-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_17485 e7031054ec8281d50208145d96cc1336 354 SUPERFAMILY SSF103486 8 334 1.83E-26 T 13-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_17485 e7031054ec8281d50208145d96cc1336 354 Gene3D G3DSA:1.10.132.50 8 332 2.2E-28 T 13-10-2018 THITH_17485 e7031054ec8281d50208145d96cc1336 354 Pfam PF01992 ATP synthase (C/AC39) subunit 10 332 4.9E-42 T 13-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_17485 e7031054ec8281d50208145d96cc1336 354 Gene3D G3DSA:1.20.1690.10 187 300 2.2E-28 T 13-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_03180 404a0c1ffd8498ef5d9677aea4e00cfb 143 Gene3D G3DSA:3.10.580.10 1 142 2.6E-31 T 13-10-2018 THITH_03180 404a0c1ffd8498ef5d9677aea4e00cfb 143 SUPERFAMILY SSF54631 4 120 4.3E-28 T 13-10-2018 THITH_03180 404a0c1ffd8498ef5d9677aea4e00cfb 143 SMART SM00116 74 121 7.5E-4 T 13-10-2018 IPR000644 CBS domain THITH_03180 404a0c1ffd8498ef5d9677aea4e00cfb 143 SMART SM00116 13 61 2.3E-8 T 13-10-2018 IPR000644 CBS domain THITH_03180 404a0c1ffd8498ef5d9677aea4e00cfb 143 Pfam PF00571 CBS domain 4 59 2.2E-12 T 13-10-2018 IPR000644 CBS domain THITH_03180 404a0c1ffd8498ef5d9677aea4e00cfb 143 Pfam PF00571 CBS domain 67 118 1.6E-7 T 13-10-2018 IPR000644 CBS domain THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 1.2E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 313 328 1.2E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 634 647 1.2E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 189 204 1.2E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 394 413 1.2E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 1.2E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 351 368 1.2E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 3.3E-88 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 3.3E-88 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 3.3E-88 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 3.3E-88 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 3.3E-88 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 3.3E-88 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 3.3E-88 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 3.3E-88 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 Pfam PF01578 Cytochrome C assembly protein 89 295 6.8E-52 T 13-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 641 4.4E-124 T 13-10-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal THITH_06890 102a349a93b2c07a2541ea8269a04fa5 670 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 644 7.1E-224 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_12320 c22e0bb93623290d5220ec8e8635079f 87 SUPERFAMILY SSF55248 3 80 1.7E-14 T 13-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 THITH_12320 c22e0bb93623290d5220ec8e8635079f 87 Gene3D G3DSA:3.30.1360.20 1 84 2.4E-32 T 13-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 THITH_12320 c22e0bb93623290d5220ec8e8635079f 87 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 3 78 5.4E-9 T 13-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 THITH_14395 2c5e443cbebb834eb35abf5cd61e878f 284 Pfam PF01478 Type IV leader peptidase family 135 243 1.4E-26 T 13-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 THITH_14395 2c5e443cbebb834eb35abf5cd61e878f 284 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 18 123 2.1E-33 T 13-10-2018 IPR010627 Peptidase A24A, N-terminal THITH_14395 2c5e443cbebb834eb35abf5cd61e878f 284 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 211 222 4.2E-27 T 13-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial THITH_14395 2c5e443cbebb834eb35abf5cd61e878f 284 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 143 160 4.2E-27 T 13-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial THITH_14395 2c5e443cbebb834eb35abf5cd61e878f 284 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 200 210 4.2E-27 T 13-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial THITH_14395 2c5e443cbebb834eb35abf5cd61e878f 284 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 223 238 4.2E-27 T 13-10-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial THITH_15185 bc82196820d3460fa1e7f5fd8cc30874 306 SUPERFAMILY SSF56752 1 303 1.31E-106 T 13-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 THITH_15185 bc82196820d3460fa1e7f5fd8cc30874 306 Gene3D G3DSA:3.20.10.10 130 295 5.2E-57 T 13-10-2018 THITH_15185 bc82196820d3460fa1e7f5fd8cc30874 306 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 11 306 1.9E-136 T 13-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 THITH_15185 bc82196820d3460fa1e7f5fd8cc30874 306 Gene3D G3DSA:3.30.470.10 2 129 1.1E-41 T 13-10-2018 THITH_15185 bc82196820d3460fa1e7f5fd8cc30874 306 Pfam PF01063 Amino-transferase class IV 36 267 1.5E-53 T 13-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 THITH_15185 bc82196820d3460fa1e7f5fd8cc30874 306 ProSitePatterns PS00770 Aminotransferases class-IV signature. 194 222 - T 13-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 THITH_10200 ea447a8eda8c3dadfda7ff2297bd40b0 145 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 13 33 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_10200 ea447a8eda8c3dadfda7ff2297bd40b0 145 PRINTS PR00813 Bacterial general secretion pathway protein G signature 50 68 3.7E-12 T 13-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THITH_10200 ea447a8eda8c3dadfda7ff2297bd40b0 145 PRINTS PR00813 Bacterial general secretion pathway protein G signature 14 39 3.7E-12 T 13-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THITH_10200 ea447a8eda8c3dadfda7ff2297bd40b0 145 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 34 1.6E-8 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_10200 ea447a8eda8c3dadfda7ff2297bd40b0 145 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 12 34 1.0E-7 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_10200 ea447a8eda8c3dadfda7ff2297bd40b0 145 Gene3D G3DSA:3.30.700.10 37 144 2.3E-34 T 13-10-2018 THITH_10200 ea447a8eda8c3dadfda7ff2297bd40b0 145 SUPERFAMILY SSF54523 40 144 3.35E-34 T 13-10-2018 THITH_10200 ea447a8eda8c3dadfda7ff2297bd40b0 145 Pfam PF08334 Type II secretion system (T2SS), protein G 37 144 3.9E-41 T 13-10-2018 IPR013545 Type II secretion system protein G THITH_10200 ea447a8eda8c3dadfda7ff2297bd40b0 145 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 13 145 2.6E-49 T 13-10-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 THITH_16465 a81f910d2162988e3bf9b3176ef430f9 287 Hamap MF_00961 RNA polymerase sigma factor RpoH [rpoH]. 4 287 48.925 T 13-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 THITH_16465 a81f910d2162988e3bf9b3176ef430f9 287 TIGRFAM TIGR02392 rpoH_proteo: alternative sigma factor RpoH 17 286 9.4E-117 T 13-10-2018 IPR012759 RNA polymerase sigma factor RpoH, proteobacteria GO:0003700|GO:0006352|GO:0006355|GO:0016987 THITH_16465 a81f910d2162988e3bf9b3176ef430f9 287 SUPERFAMILY SSF88659 210 285 2.06E-16 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like THITH_16465 a81f910d2162988e3bf9b3176ef430f9 287 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 255 281 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_16465 a81f910d2162988e3bf9b3176ef430f9 287 Gene3D G3DSA:1.20.140.160 131 287 2.3E-15 T 13-10-2018 THITH_16465 a81f910d2162988e3bf9b3176ef430f9 287 PIRSF PIRSF000770 10 287 3.9E-32 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_16465 a81f910d2162988e3bf9b3176ef430f9 287 Pfam PF04542 Sigma-70 region 2 56 125 4.0E-17 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 THITH_16465 a81f910d2162988e3bf9b3176ef430f9 287 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 51 285 5.3E-33 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 THITH_16465 a81f910d2162988e3bf9b3176ef430f9 287 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 80 93 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_16465 a81f910d2162988e3bf9b3176ef430f9 287 PRINTS PR00046 Major sigma-70 factor signature 270 281 7.7E-18 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_16465 a81f910d2162988e3bf9b3176ef430f9 287 PRINTS PR00046 Major sigma-70 factor signature 80 93 7.7E-18 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_16465 a81f910d2162988e3bf9b3176ef430f9 287 PRINTS PR00046 Major sigma-70 factor signature 255 270 7.7E-18 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_16465 a81f910d2162988e3bf9b3176ef430f9 287 PRINTS PR00046 Major sigma-70 factor signature 236 248 7.7E-18 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_16465 a81f910d2162988e3bf9b3176ef430f9 287 Gene3D G3DSA:1.10.601.10 15 125 1.8E-29 T 13-10-2018 THITH_16465 a81f910d2162988e3bf9b3176ef430f9 287 Pfam PF04545 Sigma-70, region 4 233 283 7.9E-15 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 THITH_16465 a81f910d2162988e3bf9b3176ef430f9 287 SUPERFAMILY SSF88946 17 125 6.93E-39 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 THITH_10235 e4bb47e8b979e170464c8c95818441da 1177 Pfam PF13514 AAA domain 2 208 1.8E-78 T 13-10-2018 IPR038734 Uncharacterized protein YhaN, AAA domain THITH_10235 e4bb47e8b979e170464c8c95818441da 1177 SUPERFAMILY SSF52540 9 1160 1.63E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_10235 e4bb47e8b979e170464c8c95818441da 1177 Gene3D G3DSA:3.40.50.300 938 1169 3.7E-15 T 13-10-2018 THITH_10235 e4bb47e8b979e170464c8c95818441da 1177 Gene3D G3DSA:3.40.50.300 2 404 9.5E-14 T 13-10-2018 THITH_03370 9858bba48a69cafb706ea31c6dd1d480 122 SUPERFAMILY SSF159941 9 106 5.36E-31 T 13-10-2018 IPR024047 MM3350-like superfamily THITH_03370 9858bba48a69cafb706ea31c6dd1d480 122 Gene3D G3DSA:3.10.290.30 3 108 8.5E-34 T 13-10-2018 IPR024047 MM3350-like superfamily THITH_03370 9858bba48a69cafb706ea31c6dd1d480 122 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 9 103 1.1E-31 T 13-10-2018 IPR012912 Plasmid pRiA4b, Orf3 THITH_02620 efaff6df7a1b4a256273082f9f23fb25 637 SMART SM00861 315 479 2.7E-66 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THITH_02620 efaff6df7a1b4a256273082f9f23fb25 637 ProSitePatterns PS00802 Transketolase signature 2. 421 437 - T 13-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THITH_02620 efaff6df7a1b4a256273082f9f23fb25 637 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 7 278 4.5E-121 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THITH_02620 efaff6df7a1b4a256273082f9f23fb25 637 SUPERFAMILY SSF52518 313 499 8.16E-57 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold THITH_02620 efaff6df7a1b4a256273082f9f23fb25 637 Gene3D G3DSA:3.40.50.920 491 613 6.3E-42 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 THITH_02620 efaff6df7a1b4a256273082f9f23fb25 637 ProSitePatterns PS00801 Transketolase signature 1. 32 51 - T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THITH_02620 efaff6df7a1b4a256273082f9f23fb25 637 SUPERFAMILY SSF52518 4 377 7.93E-82 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold THITH_02620 efaff6df7a1b4a256273082f9f23fb25 637 SUPERFAMILY SSF52922 487 612 3.4E-31 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 THITH_02620 efaff6df7a1b4a256273082f9f23fb25 637 Gene3D G3DSA:3.40.50.970 312 484 5.1E-65 T 13-10-2018 THITH_02620 efaff6df7a1b4a256273082f9f23fb25 637 Pfam PF02779 Transketolase, pyrimidine binding domain 314 474 1.8E-37 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THITH_02620 efaff6df7a1b4a256273082f9f23fb25 637 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 6 616 46.094 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THITH_02620 efaff6df7a1b4a256273082f9f23fb25 637 Pfam PF02780 Transketolase, C-terminal domain 491 607 3.4E-27 T 13-10-2018 IPR033248 Transketolase, C-terminal domain THITH_02620 efaff6df7a1b4a256273082f9f23fb25 637 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 9 611 3.1E-264 T 13-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THITH_15940 c38bb9e2b5c642333460c7f3aa2d3840 392 SUPERFAMILY SSF53748 3 388 1.3E-149 T 13-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15940 c38bb9e2b5c642333460c7f3aa2d3840 392 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 13-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15940 c38bb9e2b5c642333460c7f3aa2d3840 392 PRINTS PR00477 Phosphoglycerate kinase family signature 104 119 1.2E-85 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15940 c38bb9e2b5c642333460c7f3aa2d3840 392 PRINTS PR00477 Phosphoglycerate kinase family signature 163 185 1.2E-85 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15940 c38bb9e2b5c642333460c7f3aa2d3840 392 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 1.2E-85 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15940 c38bb9e2b5c642333460c7f3aa2d3840 392 PRINTS PR00477 Phosphoglycerate kinase family signature 308 333 1.2E-85 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15940 c38bb9e2b5c642333460c7f3aa2d3840 392 PRINTS PR00477 Phosphoglycerate kinase family signature 364 381 1.2E-85 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15940 c38bb9e2b5c642333460c7f3aa2d3840 392 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 1.2E-85 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15940 c38bb9e2b5c642333460c7f3aa2d3840 392 PRINTS PR00477 Phosphoglycerate kinase family signature 132 154 1.2E-85 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15940 c38bb9e2b5c642333460c7f3aa2d3840 392 PRINTS PR00477 Phosphoglycerate kinase family signature 341 352 1.2E-85 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15940 c38bb9e2b5c642333460c7f3aa2d3840 392 PRINTS PR00477 Phosphoglycerate kinase family signature 186 205 1.2E-85 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15940 c38bb9e2b5c642333460c7f3aa2d3840 392 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 388 40.306 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15940 c38bb9e2b5c642333460c7f3aa2d3840 392 Gene3D G3DSA:3.40.50.1260 165 378 1.5E-155 T 13-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15940 c38bb9e2b5c642333460c7f3aa2d3840 392 Gene3D G3DSA:3.40.50.1260 8 386 1.5E-155 T 13-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15940 c38bb9e2b5c642333460c7f3aa2d3840 392 Pfam PF00162 Phosphoglycerate kinase 6 378 3.0E-145 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15940 c38bb9e2b5c642333460c7f3aa2d3840 392 PIRSF PIRSF000724 1 392 4.3E-139 T 13-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_17460 4ab65445c4bb83b741690eda06cfa108 599 SUPERFAMILY SSF52540 186 441 1.68E-80 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_17460 4ab65445c4bb83b741690eda06cfa108 599 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 430 439 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_17460 4ab65445c4bb83b741690eda06cfa108 599 Gene3D G3DSA:2.40.30.20 1 74 9.6E-18 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_17460 4ab65445c4bb83b741690eda06cfa108 599 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 5 591 48.168 T 13-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_17460 4ab65445c4bb83b741690eda06cfa108 599 SUPERFAMILY SSF47917 451 538 7.85E-14 T 13-10-2018 THITH_17460 4ab65445c4bb83b741690eda06cfa108 599 Gene3D G3DSA:2.40.50.100 118 191 3.6E-168 T 13-10-2018 THITH_17460 4ab65445c4bb83b741690eda06cfa108 599 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 218 439 3.2E-88 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_17460 4ab65445c4bb83b741690eda06cfa108 599 SUPERFAMILY SSF50615 4 72 1.1E-6 T 13-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_17460 4ab65445c4bb83b741690eda06cfa108 599 Gene3D G3DSA:3.40.50.300 75 439 3.6E-168 T 13-10-2018 THITH_17460 4ab65445c4bb83b741690eda06cfa108 599 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 13 71 6.6E-6 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_17460 4ab65445c4bb83b741690eda06cfa108 599 Gene3D G3DSA:1.10.1140.10 441 593 1.5E-36 T 13-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_17460 4ab65445c4bb83b741690eda06cfa108 599 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 87 208 1.1E-42 T 13-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_10220 7707623ccad554e6f08805ae1669c637 304 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 14 298 4.5E-151 T 13-10-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 THITH_10220 7707623ccad554e6f08805ae1669c637 304 SUPERFAMILY SSF53448 13 299 7.58E-89 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_10220 7707623ccad554e6f08805ae1669c637 304 Gene3D G3DSA:3.90.550.10 7 303 3.0E-83 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_10220 7707623ccad554e6f08805ae1669c637 304 Pfam PF00483 Nucleotidyl transferase 14 249 4.8E-66 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 THITH_12780 872cfe363c3fb9be869020e3d6d88f20 70 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 48 1.0E-7 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THITH_12780 872cfe363c3fb9be869020e3d6d88f20 70 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 45 4.0E-10 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THITH_12780 872cfe363c3fb9be869020e3d6d88f20 70 SUPERFAMILY SSF89447 3 47 9.59E-8 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily THITH_12780 872cfe363c3fb9be869020e3d6d88f20 70 Gene3D G3DSA:2.10.260.10 1 43 1.2E-6 T 13-10-2018 THITH_12780 872cfe363c3fb9be869020e3d6d88f20 70 SMART SM00966 5 50 3.8E-8 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THITH_10420 6a954a0fdc84ed4567538f0b5d6aa100 761 Gene3D G3DSA:3.10.20.310 94 175 4.7E-18 T 13-10-2018 THITH_10420 6a954a0fdc84ed4567538f0b5d6aa100 761 Gene3D G3DSA:3.10.20.310 20 93 1.2E-18 T 13-10-2018 THITH_10420 6a954a0fdc84ed4567538f0b5d6aa100 761 Pfam PF07244 Surface antigen variable number repeat 268 346 1.7E-11 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 THITH_10420 6a954a0fdc84ed4567538f0b5d6aa100 761 Pfam PF07244 Surface antigen variable number repeat 26 92 6.4E-5 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 THITH_10420 6a954a0fdc84ed4567538f0b5d6aa100 761 Pfam PF07244 Surface antigen variable number repeat 178 265 5.6E-16 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 THITH_10420 6a954a0fdc84ed4567538f0b5d6aa100 761 Pfam PF07244 Surface antigen variable number repeat 349 423 2.7E-9 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 THITH_10420 6a954a0fdc84ed4567538f0b5d6aa100 761 Pfam PF07244 Surface antigen variable number repeat 95 174 3.8E-13 T 13-10-2018 IPR010827 POTRA domain, BamA/TamA-like GO:0019867 THITH_10420 6a954a0fdc84ed4567538f0b5d6aa100 761 Gene3D G3DSA:3.10.20.310 269 345 1.6E-18 T 13-10-2018 THITH_10420 6a954a0fdc84ed4567538f0b5d6aa100 761 Hamap MF_01430 Outer membrane protein assembly factor BamA [bamA]. 9 761 24.539 T 13-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 THITH_10420 6a954a0fdc84ed4567538f0b5d6aa100 761 Gene3D G3DSA:3.10.20.310 177 268 1.8E-21 T 13-10-2018 THITH_10420 6a954a0fdc84ed4567538f0b5d6aa100 761 Gene3D G3DSA:3.10.20.310 346 423 7.8E-21 T 13-10-2018 THITH_10420 6a954a0fdc84ed4567538f0b5d6aa100 761 Pfam PF01103 Surface antigen 450 761 5.2E-71 T 13-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 THITH_10420 6a954a0fdc84ed4567538f0b5d6aa100 761 Gene3D G3DSA:2.40.160.50 425 761 9.5E-105 T 13-10-2018 THITH_10420 6a954a0fdc84ed4567538f0b5d6aa100 761 TIGRFAM TIGR03303 OM_YaeT: outer membrane protein assembly complex, YaeT protein 27 761 2.9E-254 T 13-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 THITH_10420 6a954a0fdc84ed4567538f0b5d6aa100 761 PIRSF PIRSF006076 1 761 1.2E-242 T 13-10-2018 IPR023707 Outer membrane protein assembly factor BamA GO:0071709 THITH_09115 0d96de284344f62174ad8774d55f866a 441 TIGRFAM TIGR03467 HpnE: squalene-associated FAD-dependent desaturase 6 437 3.3E-106 T 13-10-2018 IPR017830 Hydroxysqualene dehydroxylase HpnE MetaCyc: PWY-7072 THITH_09115 0d96de284344f62174ad8774d55f866a 441 Gene3D G3DSA:3.50.50.60 2 440 1.5E-30 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_09115 0d96de284344f62174ad8774d55f866a 441 SUPERFAMILY SSF51905 5 437 1.54E-54 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_09115 0d96de284344f62174ad8774d55f866a 441 Pfam PF01593 Flavin containing amine oxidoreductase 14 436 1.3E-33 T 13-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 THITH_01250 287b28f514f6dc2f0375876bf3bd2ee9 693 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 4 690 25.196 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THITH_01250 287b28f514f6dc2f0375876bf3bd2ee9 693 Pfam PF05746 DALR anticodon binding domain 584 678 3.9E-8 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 THITH_01250 287b28f514f6dc2f0375876bf3bd2ee9 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 319 335 3.0E-33 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THITH_01250 287b28f514f6dc2f0375876bf3bd2ee9 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 247 262 3.0E-33 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THITH_01250 287b28f514f6dc2f0375876bf3bd2ee9 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 51 63 3.0E-33 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THITH_01250 287b28f514f6dc2f0375876bf3bd2ee9 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 8 21 3.0E-33 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THITH_01250 287b28f514f6dc2f0375876bf3bd2ee9 693 PRINTS PR01045 Glycyl-tRNA synthetase beta subunit signature 395 414 3.0E-33 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THITH_01250 287b28f514f6dc2f0375876bf3bd2ee9 693 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 7 552 5.1E-203 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THITH_01250 287b28f514f6dc2f0375876bf3bd2ee9 693 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 6 690 3.5E-224 T 13-10-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THITH_01250 287b28f514f6dc2f0375876bf3bd2ee9 693 SMART SM00836 587 690 0.003 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 THITH_01250 287b28f514f6dc2f0375876bf3bd2ee9 693 SUPERFAMILY SSF109604 341 491 2.38E-19 T 13-10-2018 THITH_16930 f21774f21346905c53d73f8c96eba4f8 91 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 58 1.0E-23 T 13-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_16930 f21774f21346905c53d73f8c96eba4f8 91 SUPERFAMILY SSF63562 1 75 5.49E-25 T 13-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 THITH_16930 f21774f21346905c53d73f8c96eba4f8 91 Pfam PF01192 RNA polymerase Rpb6 8 58 4.1E-17 T 13-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 THITH_16930 f21774f21346905c53d73f8c96eba4f8 91 SMART SM01409 8 60 7.0E-19 T 13-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 THITH_16930 f21774f21346905c53d73f8c96eba4f8 91 Gene3D G3DSA:3.90.940.10 1 87 1.5E-26 T 13-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 THITH_16930 f21774f21346905c53d73f8c96eba4f8 91 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 61 18.198 T 13-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_17440 35c1802db68975c6f5e03fe1a09a0650 316 Gene3D G3DSA:3.40.50.1820 1 312 7.2E-109 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_17440 35c1802db68975c6f5e03fe1a09a0650 316 SUPERFAMILY SSF53474 5 311 5.99E-65 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_17440 35c1802db68975c6f5e03fe1a09a0650 316 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 37 45 7.4E-13 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 THITH_17440 35c1802db68975c6f5e03fe1a09a0650 316 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 106 120 7.4E-13 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 THITH_17440 35c1802db68975c6f5e03fe1a09a0650 316 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 63 74 7.4E-13 T 13-10-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 THITH_17440 35c1802db68975c6f5e03fe1a09a0650 316 PRINTS PR00111 Alpha/beta hydrolase fold signature 106 119 1.8E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_17440 35c1802db68975c6f5e03fe1a09a0650 316 PRINTS PR00111 Alpha/beta hydrolase fold signature 120 133 1.8E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_17440 35c1802db68975c6f5e03fe1a09a0650 316 PRINTS PR00111 Alpha/beta hydrolase fold signature 60 75 1.8E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_17440 35c1802db68975c6f5e03fe1a09a0650 316 Pfam PF00561 alpha/beta hydrolase fold 38 296 2.3E-29 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_17440 35c1802db68975c6f5e03fe1a09a0650 316 PIRSF PIRSF006431 1 315 4.1E-140 T 13-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 THITH_17440 35c1802db68975c6f5e03fe1a09a0650 316 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 9 311 1.1E-130 T 13-10-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 THITH_12380 e444f45f8acdb6e7a356bfedb01a6173 137 Pfam PF14760 Rnk N-terminus 5 45 3.9E-10 T 13-10-2018 IPR029462 Regulator of nucleoside diphosphate kinase, N-terminal domain THITH_12380 e444f45f8acdb6e7a356bfedb01a6173 137 Gene3D G3DSA:1.10.286.20 1 45 7.5E-9 T 13-10-2018 THITH_12380 e444f45f8acdb6e7a356bfedb01a6173 137 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 53 127 2.1E-20 T 13-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 THITH_12380 e444f45f8acdb6e7a356bfedb01a6173 137 PIRSF PIRSF006092 22 129 7.1E-25 T 13-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 THITH_12380 e444f45f8acdb6e7a356bfedb01a6173 137 SUPERFAMILY SSF54534 50 128 3.4E-18 T 13-10-2018 THITH_12380 e444f45f8acdb6e7a356bfedb01a6173 137 Gene3D G3DSA:3.10.50.30 46 137 1.1E-30 T 13-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 THITH_11680 56782d197ab068d36089df2d2613ba7e 212 SUPERFAMILY SSF81342 6 210 2.98E-49 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THITH_11680 56782d197ab068d36089df2d2613ba7e 212 Gene3D G3DSA:1.20.950.20 3 212 4.5E-67 T 13-10-2018 THITH_11680 56782d197ab068d36089df2d2613ba7e 212 Pfam PF01292 Prokaryotic cytochrome b561 10 188 4.8E-24 T 13-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THITH_11680 56782d197ab068d36089df2d2613ba7e 212 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 8 207 2.9E-60 T 13-10-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 SUPERFAMILY SSF55785 612 744 7.33E-23 T 13-10-2018 IPR035965 PAS domain superfamily THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 SMART SM00086 573 615 6.3E-10 T 13-10-2018 IPR001610 PAC motif THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 SMART SM00086 706 746 8.4 T 13-10-2018 IPR001610 PAC motif THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 SMART SM00086 446 487 11.0 T 13-10-2018 IPR001610 PAC motif THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 SUPERFAMILY SSF55785 383 488 1.71E-12 T 13-10-2018 IPR035965 PAS domain superfamily THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 Pfam PF08448 PAS fold 772 877 3.0E-6 T 13-10-2018 IPR013656 PAS fold-4 THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 Gene3D G3DSA:3.30.70.270 881 1047 8.7E-61 T 13-10-2018 THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 SMART SM00091 499 567 2.6E-4 T 13-10-2018 IPR000014 PAS domain THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 SMART SM00091 758 831 9.5 T 13-10-2018 IPR000014 PAS domain THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 SMART SM00091 371 441 1.7 T 13-10-2018 IPR000014 PAS domain THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 SMART SM00091 627 698 5.4E-6 T 13-10-2018 IPR000014 PAS domain THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 Gene3D G3DSA:3.30.450.20 492 611 5.9E-34 T 13-10-2018 THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 Gene3D G3DSA:3.30.450.20 753 880 6.9E-13 T 13-10-2018 THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 SUPERFAMILY SSF55785 484 613 2.44E-23 T 13-10-2018 IPR035965 PAS domain superfamily THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 Gene3D G3DSA:2.10.70.100 443 488 1.3E-10 T 13-10-2018 THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 Gene3D G3DSA:3.30.450.20 371 442 1.9E-16 T 13-10-2018 THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 SUPERFAMILY SSF55073 891 1045 7.14E-52 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 Pfam PF14827 Double sensory domain of two-component sensor kinase 48 301 1.8E-20 T 13-10-2018 IPR029150 Double Cache domain 3 THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 SMART SM00267 875 1047 5.9E-63 T 13-10-2018 IPR000160 GGDEF domain THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 Pfam PF08447 PAS fold 398 481 3.5E-14 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 Pfam PF08447 PAS fold 522 609 1.1E-22 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 Gene3D G3DSA:3.30.450.20 636 752 2.0E-24 T 13-10-2018 THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 Pfam PF13426 PAS domain 638 745 5.0E-13 T 13-10-2018 IPR000014 PAS domain THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 SUPERFAMILY SSF55785 744 873 6.63E-11 T 13-10-2018 IPR035965 PAS domain superfamily THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 495 622 4.7E-12 T 13-10-2018 IPR000014 PAS domain THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 398 494 4.7E-7 T 13-10-2018 IPR000014 PAS domain THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 636 753 3.7E-15 T 13-10-2018 IPR000014 PAS domain THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 882 1047 1.9E-52 T 13-10-2018 IPR000160 GGDEF domain THITH_12710 3b52aa2981e1d22b298f7c4c539813f8 1048 Pfam PF00990 Diguanylate cyclase, GGDEF domain 886 1043 3.5E-47 T 13-10-2018 IPR000160 GGDEF domain THITH_15305 4e9d2b24cbd251d3a678ce0807b6ce7a 765 SUPERFAMILY SSF74863 28 144 1.44E-32 T 13-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily THITH_15305 4e9d2b24cbd251d3a678ce0807b6ce7a 765 Pfam PF13899 Thioredoxin-like 651 733 1.3E-14 T 13-10-2018 THITH_15305 4e9d2b24cbd251d3a678ce0807b6ce7a 765 Gene3D G3DSA:3.40.30.10 636 761 6.3E-32 T 13-10-2018 THITH_15305 4e9d2b24cbd251d3a678ce0807b6ce7a 765 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 346 551 2.4E-16 T 13-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 THITH_15305 4e9d2b24cbd251d3a678ce0807b6ce7a 765 SUPERFAMILY SSF52833 656 758 8.28E-24 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_15305 4e9d2b24cbd251d3a678ce0807b6ce7a 765 Gene3D G3DSA:2.60.40.1250 171 309 2.7E-33 T 13-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily THITH_15305 4e9d2b24cbd251d3a678ce0807b6ce7a 765 Gene3D G3DSA:2.60.40.1250 21 160 6.3E-39 T 13-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily THITH_15305 4e9d2b24cbd251d3a678ce0807b6ce7a 765 Hamap MF_00399 Thiol:disulfide interchange protein DsbD [dsbD]. 6 761 35.106 T 13-10-2018 IPR022910 Thiol:disulphide interchange protein DsbD GO:0047134|GO:0055114 THITH_15305 4e9d2b24cbd251d3a678ce0807b6ce7a 765 Pfam PF11412 Disulphide bond corrector protein DsbC 177 293 2.2E-30 T 13-10-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain THITH_15305 4e9d2b24cbd251d3a678ce0807b6ce7a 765 Pfam PF11412 Disulphide bond corrector protein DsbC 30 144 2.6E-29 T 13-10-2018 IPR028250 Thiol:disulfide interchange protein DsbD, N-terminal domain THITH_15305 4e9d2b24cbd251d3a678ce0807b6ce7a 765 SUPERFAMILY SSF74863 175 294 2.62E-30 T 13-10-2018 IPR036929 Thiol:disulfide interchange protein DsbD, N-terminal domain superfamily THITH_06440 4510764af93ad36737a61b32132b1143 202 Gene3D G3DSA:1.10.760.10 40 202 9.2E-73 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_06440 4510764af93ad36737a61b32132b1143 202 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 3 179 1.5E-82 T 13-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO THITH_06440 4510764af93ad36737a61b32132b1143 202 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 3 177 4.5E-87 T 13-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO THITH_06440 4510764af93ad36737a61b32132b1143 202 SUPERFAMILY SSF46626 13 194 5.78E-28 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_10555 bc6eff46c33db03da8e6ee66abb66e84 219 Gene3D G3DSA:3.40.1050.10 1 219 2.1E-82 T 13-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 THITH_10555 bc6eff46c33db03da8e6ee66abb66e84 219 SUPERFAMILY SSF53056 6 211 2.22E-35 T 13-10-2018 IPR036874 Carbonic anhydrase superfamily GO:0004089|GO:0008270 THITH_10555 bc6eff46c33db03da8e6ee66abb66e84 219 SMART SM00947 32 210 5.6E-25 T 13-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THITH_10555 bc6eff46c33db03da8e6ee66abb66e84 219 Pfam PF00484 Carbonic anhydrase 40 206 5.1E-14 T 13-10-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 THITH_04240 400c3583e22081acaa604e50ccd28f0c 188 Gene3D G3DSA:3.40.50.150 5 171 2.8E-30 T 13-10-2018 THITH_04240 400c3583e22081acaa604e50ccd28f0c 188 SUPERFAMILY SSF53335 16 166 4.22E-32 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_04240 400c3583e22081acaa604e50ccd28f0c 188 Pfam PF13649 Methyltransferase domain 33 127 1.5E-14 T 13-10-2018 THITH_17340 d6caddb256ec33d1eff001fcec5c7661 161 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 5 60 1.5E-13 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THITH_17340 d6caddb256ec33d1eff001fcec5c7661 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 8.5E-48 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THITH_17340 d6caddb256ec33d1eff001fcec5c7661 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 8.5E-48 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THITH_17340 d6caddb256ec33d1eff001fcec5c7661 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 8.5E-48 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THITH_17340 d6caddb256ec33d1eff001fcec5c7661 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 8.5E-48 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THITH_17340 d6caddb256ec33d1eff001fcec5c7661 161 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 8.5E-48 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THITH_17340 d6caddb256ec33d1eff001fcec5c7661 161 Pfam PF01467 Cytidylyltransferase-like 6 134 3.1E-19 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THITH_17340 d6caddb256ec33d1eff001fcec5c7661 161 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 34.188 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THITH_17340 d6caddb256ec33d1eff001fcec5c7661 161 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 157 4.6E-54 T 13-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 THITH_17340 d6caddb256ec33d1eff001fcec5c7661 161 SUPERFAMILY SSF52374 4 157 2.12E-40 T 13-10-2018 THITH_17340 d6caddb256ec33d1eff001fcec5c7661 161 Gene3D G3DSA:3.40.50.620 1 160 5.9E-54 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_08385 16368937877f80e66c9aae17e57d964f 611 Gene3D G3DSA:3.40.50.1220 269 389 7.5E-26 T 13-10-2018 THITH_08385 16368937877f80e66c9aae17e57d964f 611 PIRSF PIRSF004983 7 611 8.6E-144 T 13-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 THITH_08385 16368937877f80e66c9aae17e57d964f 611 SUPERFAMILY SSF52518 420 603 6.88E-25 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold THITH_08385 16368937877f80e66c9aae17e57d964f 611 SUPERFAMILY SSF52518 17 193 2.45E-29 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold THITH_08385 16368937877f80e66c9aae17e57d964f 611 Gene3D G3DSA:3.40.50.970 405 609 2.4E-55 T 13-10-2018 THITH_08385 16368937877f80e66c9aae17e57d964f 611 SUPERFAMILY SSF52467 271 390 7.09E-5 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily THITH_08385 16368937877f80e66c9aae17e57d964f 611 Gene3D G3DSA:3.40.50.970 7 182 1.1E-57 T 13-10-2018 THITH_08385 16368937877f80e66c9aae17e57d964f 611 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 475 588 1.1E-7 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THITH_08385 16368937877f80e66c9aae17e57d964f 611 Pfam PF16582 Middle domain of thiamine pyrophosphate 274 438 8.8E-23 T 13-10-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 THITH_08385 16368937877f80e66c9aae17e57d964f 611 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 15 186 1.5E-25 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 THITH_08385 16368937877f80e66c9aae17e57d964f 611 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 8 607 32.292 T 13-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 THITH_14590 4396d80f7f2501ea785dba3dac6fce2d 214 Gene3D G3DSA:3.40.190.10 8 202 1.2E-70 T 13-10-2018 THITH_14590 4396d80f7f2501ea785dba3dac6fce2d 214 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 7 187 1.8E-56 T 13-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 THITH_14590 4396d80f7f2501ea785dba3dac6fce2d 214 Pfam PF01634 ATP phosphoribosyltransferase 56 207 5.2E-49 T 13-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 THITH_14590 4396d80f7f2501ea785dba3dac6fce2d 214 SUPERFAMILY SSF53850 5 210 7.17E-65 T 13-10-2018 THITH_14590 4396d80f7f2501ea785dba3dac6fce2d 214 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 6 211 55.493 T 13-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 THITH_14590 4396d80f7f2501ea785dba3dac6fce2d 214 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 146 167 - T 13-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 THITH_14590 4396d80f7f2501ea785dba3dac6fce2d 214 Gene3D G3DSA:3.40.190.10 98 179 1.2E-70 T 13-10-2018 THITH_13600 a8741960208f64f1b8324845d93a43e0 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 264 282 3.9E-49 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_13600 a8741960208f64f1b8324845d93a43e0 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 147 166 3.9E-49 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_13600 a8741960208f64f1b8324845d93a43e0 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 468 486 3.9E-49 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_13600 a8741960208f64f1b8324845d93a43e0 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 500 513 3.9E-49 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_13600 a8741960208f64f1b8324845d93a43e0 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 341 362 3.9E-49 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_13600 a8741960208f64f1b8324845d93a43e0 554 PRINTS PR00662 Glucose-6-phosphate isomerase signature 486 500 3.9E-49 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_13600 a8741960208f64f1b8324845d93a43e0 554 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 43 527 38.624 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_13600 a8741960208f64f1b8324845d93a43e0 554 SUPERFAMILY SSF53697 9 549 1.11E-187 T 13-10-2018 THITH_13600 a8741960208f64f1b8324845d93a43e0 554 Pfam PF00342 Phosphoglucose isomerase 49 543 1.3E-184 T 13-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_13600 a8741960208f64f1b8324845d93a43e0 554 Gene3D G3DSA:3.40.50.10490 95 294 6.9E-203 T 13-10-2018 THITH_13600 a8741960208f64f1b8324845d93a43e0 554 Gene3D G3DSA:1.10.1390.10 510 552 6.6E-15 T 13-10-2018 IPR023096 Phosphoglucose isomerase, C-terminal GO:0004347|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_13600 a8741960208f64f1b8324845d93a43e0 554 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 500 517 - T 13-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_13600 a8741960208f64f1b8324845d93a43e0 554 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 268 281 - T 13-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_13600 a8741960208f64f1b8324845d93a43e0 554 Gene3D G3DSA:3.40.50.10490 10 509 6.9E-203 T 13-10-2018 THITH_09160 e68466fcbf1f8d960243654bac883437 231 Pfam PF09335 SNARE associated Golgi protein 73 184 3.4E-10 T 13-10-2018 IPR032816 SNARE associated Golgi protein THITH_02945 5dfad8a0429007b6d3d9a8d644febba6 243 SUPERFAMILY SSF52402 20 240 1.98E-63 T 13-10-2018 THITH_02945 5dfad8a0429007b6d3d9a8d644febba6 243 Pfam PF06508 Queuosine biosynthesis protein QueC 20 229 1.4E-73 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 THITH_02945 5dfad8a0429007b6d3d9a8d644febba6 243 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 18 235 52.917 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 THITH_02945 5dfad8a0429007b6d3d9a8d644febba6 243 Gene3D G3DSA:3.40.50.620 17 235 4.3E-72 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_02945 5dfad8a0429007b6d3d9a8d644febba6 243 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 20 222 1.8E-56 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 THITH_02945 5dfad8a0429007b6d3d9a8d644febba6 243 PIRSF PIRSF006293 17 241 6.8E-73 T 13-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 THITH_10655 50258fb16fda7343994fc3719bab97ed 395 Pfam PF00108 Thiolase, N-terminal domain 5 263 1.1E-107 T 13-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 THITH_10655 50258fb16fda7343994fc3719bab97ed 395 ProSitePatterns PS00737 Thiolases signature 2. 340 356 - T 13-10-2018 IPR020613 Thiolase, conserved site GO:0016747 THITH_10655 50258fb16fda7343994fc3719bab97ed 395 SUPERFAMILY SSF53901 272 393 2.07E-44 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 THITH_10655 50258fb16fda7343994fc3719bab97ed 395 PIRSF PIRSF000429 1 395 1.0E-129 T 13-10-2018 IPR002155 Thiolase GO:0016747 THITH_10655 50258fb16fda7343994fc3719bab97ed 395 SUPERFAMILY SSF53901 5 271 1.52E-90 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 THITH_10655 50258fb16fda7343994fc3719bab97ed 395 Pfam PF02803 Thiolase, C-terminal domain 271 393 6.5E-51 T 13-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 THITH_10655 50258fb16fda7343994fc3719bab97ed 395 ProSitePatterns PS00099 Thiolases active site. 375 388 - T 13-10-2018 IPR020610 Thiolase, active site GO:0016747 THITH_10655 50258fb16fda7343994fc3719bab97ed 395 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 13-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 THITH_10655 50258fb16fda7343994fc3719bab97ed 395 Gene3D G3DSA:3.40.47.10 7 277 3.2E-157 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 THITH_10655 50258fb16fda7343994fc3719bab97ed 395 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 392 2.4E-149 T 13-10-2018 IPR002155 Thiolase GO:0016747 THITH_10655 50258fb16fda7343994fc3719bab97ed 395 Gene3D G3DSA:3.40.47.10 127 391 3.2E-157 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 THITH_14710 0dc56c81b845ffa510dcf0a3fb6b53a7 194 Gene3D G3DSA:1.10.4060.10 114 192 5.9E-10 T 13-10-2018 THITH_14710 0dc56c81b845ffa510dcf0a3fb6b53a7 194 SMART SM00464 3 190 6.6E-13 T 13-10-2018 IPR003111 Lon, substrate-binding domain THITH_14710 0dc56c81b845ffa510dcf0a3fb6b53a7 194 SUPERFAMILY SSF88697 3 188 5.22E-49 T 13-10-2018 IPR015947 PUA-like superfamily THITH_14710 0dc56c81b845ffa510dcf0a3fb6b53a7 194 Gene3D G3DSA:2.30.130.40 1 112 2.8E-33 T 13-10-2018 THITH_14710 0dc56c81b845ffa510dcf0a3fb6b53a7 194 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 3 184 7.1E-17 T 13-10-2018 IPR003111 Lon, substrate-binding domain THITH_13930 d077f56596b9c4f8515cf7d2613f5129 344 SUPERFAMILY SSF74653 261 341 5.49E-23 T 13-10-2018 THITH_13930 d077f56596b9c4f8515cf7d2613f5129 344 PRINTS PR01374 Gram-negative bacterial tonB protein signature 282 300 3.7E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 THITH_13930 d077f56596b9c4f8515cf7d2613f5129 344 PRINTS PR01374 Gram-negative bacterial tonB protein signature 198 208 3.7E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 THITH_13930 d077f56596b9c4f8515cf7d2613f5129 344 PRINTS PR01374 Gram-negative bacterial tonB protein signature 261 282 3.7E-7 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 THITH_13930 d077f56596b9c4f8515cf7d2613f5129 344 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 265 343 1.3E-20 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 THITH_13930 d077f56596b9c4f8515cf7d2613f5129 344 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 267 343 2.6E-20 T 13-10-2018 IPR006260 TonB/TolA, C-terminal THITH_13930 d077f56596b9c4f8515cf7d2613f5129 344 Gene3D G3DSA:3.30.1150.10 253 343 9.7E-24 T 13-10-2018 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 SUPERFAMILY SSF82866 288 487 4.84E-43 T 13-10-2018 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 Gene3D G3DSA:1.20.1640.10 499 1005 0.0 T 13-10-2018 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 Gene3D G3DSA:3.30.2090.10 702 790 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 Gene3D G3DSA:3.30.70.1430 549 647 0.0 T 13-10-2018 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 PRINTS PR00702 Acriflavin resistance protein family signature 354 375 1.4E-50 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 PRINTS PR00702 Acriflavin resistance protein family signature 462 485 1.4E-50 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 PRINTS PR00702 Acriflavin resistance protein family signature 327 350 1.4E-50 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 PRINTS PR00702 Acriflavin resistance protein family signature 534 551 1.4E-50 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 PRINTS PR00702 Acriflavin resistance protein family signature 437 460 1.4E-50 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 1.4E-50 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 PRINTS PR00702 Acriflavin resistance protein family signature 382 406 1.4E-50 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 1.4E-50 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 SUPERFAMILY SSF82714 703 786 3.01E-14 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 SUPERFAMILY SSF82693 140 319 2.01E-14 T 13-10-2018 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 Gene3D G3DSA:3.30.70.1440 648 847 0.0 T 13-10-2018 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 SUPERFAMILY SSF82693 40 132 4.71E-25 T 13-10-2018 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 Gene3D G3DSA:3.30.70.1430 40 798 0.0 T 13-10-2018 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 Gene3D G3DSA:3.30.70.1320 134 323 0.0 T 13-10-2018 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 Pfam PF00873 AcrB/AcrD/AcrF family 5 1009 2.5E-249 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 Gene3D G3DSA:1.20.1640.10 10 498 0.0 T 13-10-2018 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 Gene3D G3DSA:3.30.2090.10 177 267 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 SUPERFAMILY SSF82866 786 1010 3.27E-53 T 13-10-2018 THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 SUPERFAMILY SSF82714 181 263 3.79E-14 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_04975 98f5bd4559a3ff4e5b78f786fcc229ad 1023 SUPERFAMILY SSF82693 548 643 6.28E-9 T 13-10-2018 THITH_02785 f1c4f9768900d05ce01431186caea962 361 Pfam PF02769 AIR synthase related protein, C-terminal domain 186 351 2.8E-39 T 13-10-2018 IPR010918 PurM-like, C-terminal domain THITH_02785 f1c4f9768900d05ce01431186caea962 361 Gene3D G3DSA:3.30.1330.10 15 180 1.4E-68 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THITH_02785 f1c4f9768900d05ce01431186caea962 361 SUPERFAMILY SSF55326 16 179 1.64E-53 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THITH_02785 f1c4f9768900d05ce01431186caea962 361 Pfam PF00586 AIR synthase related protein, N-terminal domain 71 174 9.8E-17 T 13-10-2018 IPR016188 PurM-like, N-terminal domain THITH_02785 f1c4f9768900d05ce01431186caea962 361 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 16 358 47.995 T 13-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THITH_02785 f1c4f9768900d05ce01431186caea962 361 SUPERFAMILY SSF56042 181 352 2.84E-60 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THITH_02785 f1c4f9768900d05ce01431186caea962 361 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 16 349 1.3E-138 T 13-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THITH_02785 f1c4f9768900d05ce01431186caea962 361 Gene3D G3DSA:3.90.650.10 182 360 1.6E-67 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THITH_10470 3a7e3a2d0b795bc7e01bf5c53d44c222 886 Pfam PF01842 ACT domain 820 865 3.2E-9 T 13-10-2018 IPR002912 ACT domain THITH_10470 3a7e3a2d0b795bc7e01bf5c53d44c222 886 Pfam PF01966 HD domain 466 595 8.7E-12 T 13-10-2018 IPR006674 HD domain THITH_10470 3a7e3a2d0b795bc7e01bf5c53d44c222 886 Gene3D G3DSA:1.10.3210.10 456 579 1.2E-9 T 13-10-2018 THITH_10470 3a7e3a2d0b795bc7e01bf5c53d44c222 886 Pfam PF01909 Nucleotidyltransferase domain 85 114 3.5E-6 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THITH_10470 3a7e3a2d0b795bc7e01bf5c53d44c222 886 SUPERFAMILY SSF55021 705 776 3.21E-10 T 13-10-2018 THITH_10470 3a7e3a2d0b795bc7e01bf5c53d44c222 886 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 43 885 5.7E-283 T 13-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 THITH_10470 3a7e3a2d0b795bc7e01bf5c53d44c222 886 PIRSF PIRSF006288 20 886 0.0 T 13-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 THITH_10470 3a7e3a2d0b795bc7e01bf5c53d44c222 886 SUPERFAMILY SSF81593 204 317 5.02E-11 T 13-10-2018 THITH_10470 3a7e3a2d0b795bc7e01bf5c53d44c222 886 SUPERFAMILY SSF55021 814 867 7.91E-8 T 13-10-2018 THITH_10470 3a7e3a2d0b795bc7e01bf5c53d44c222 886 SMART SM00471 462 609 2.1E-10 T 13-10-2018 IPR003607 HD/PDEase domain THITH_10470 3a7e3a2d0b795bc7e01bf5c53d44c222 886 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 886 306.165 T 13-10-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 THITH_10470 3a7e3a2d0b795bc7e01bf5c53d44c222 886 Pfam PF08335 GlnD PII-uridylyltransferase 189 327 2.2E-37 T 13-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 THITH_10470 3a7e3a2d0b795bc7e01bf5c53d44c222 886 SUPERFAMILY SSF109604 433 557 9.1E-17 T 13-10-2018 THITH_10470 3a7e3a2d0b795bc7e01bf5c53d44c222 886 SUPERFAMILY SSF81301 21 180 3.87E-22 T 13-10-2018 THITH_05020 3f815e9a8a253332b62b5b316706a1bf 309 Pfam PF00850 Histone deacetylase domain 20 306 3.6E-81 T 13-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THITH_05020 3f815e9a8a253332b62b5b316706a1bf 309 SUPERFAMILY SSF52768 1 307 1.1E-101 T 13-10-2018 IPR023696 Ureohydrolase domain superfamily THITH_05020 3f815e9a8a253332b62b5b316706a1bf 309 Gene3D G3DSA:3.40.800.20 1 309 5.3E-115 T 13-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THITH_05020 3f815e9a8a253332b62b5b316706a1bf 309 PRINTS PR01270 Histone deacetylase superfamily signature 124 147 1.0E-15 T 13-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THITH_05020 3f815e9a8a253332b62b5b316706a1bf 309 PRINTS PR01270 Histone deacetylase superfamily signature 236 246 1.0E-15 T 13-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THITH_05020 3f815e9a8a253332b62b5b316706a1bf 309 PRINTS PR01270 Histone deacetylase superfamily signature 158 173 1.0E-15 T 13-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 THITH_09755 c8a35fbfeaf9ded709416bfdeb08a474 411 Pfam PF13579 Glycosyl transferase 4-like domain 1 196 4.9E-17 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 THITH_09755 c8a35fbfeaf9ded709416bfdeb08a474 411 Gene3D G3DSA:3.40.50.2000 198 383 2.2E-65 T 13-10-2018 THITH_09755 c8a35fbfeaf9ded709416bfdeb08a474 411 SUPERFAMILY SSF53756 1 400 1.18E-73 T 13-10-2018 THITH_09755 c8a35fbfeaf9ded709416bfdeb08a474 411 Pfam PF00534 Glycosyl transferases group 1 224 378 5.5E-31 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 THITH_09755 c8a35fbfeaf9ded709416bfdeb08a474 411 Gene3D G3DSA:3.40.50.2000 77 396 2.2E-65 T 13-10-2018 THITH_15620 66f8477b40183cc28d6091100011defc 338 SMART SM01004 8 332 6.9E-236 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THITH_15620 66f8477b40183cc28d6091100011defc 338 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 251 263 - T 13-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THITH_15620 66f8477b40183cc28d6091100011defc 338 SUPERFAMILY SSF51569 6 334 7.77E-142 T 13-10-2018 THITH_15620 66f8477b40183cc28d6091100011defc 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 306 325 3.9E-56 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THITH_15620 66f8477b40183cc28d6091100011defc 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 276 291 3.9E-56 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THITH_15620 66f8477b40183cc28d6091100011defc 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 159 178 3.9E-56 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THITH_15620 66f8477b40183cc28d6091100011defc 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 197 216 3.9E-56 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THITH_15620 66f8477b40183cc28d6091100011defc 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 128 142 3.9E-56 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THITH_15620 66f8477b40183cc28d6091100011defc 338 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 251 267 3.9E-56 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THITH_15620 66f8477b40183cc28d6091100011defc 338 Gene3D G3DSA:3.20.20.70 1 336 6.3E-147 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_15620 66f8477b40183cc28d6091100011defc 338 PIRSF PIRSF001415 1 335 9.9E-149 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THITH_15620 66f8477b40183cc28d6091100011defc 338 Pfam PF00490 Delta-aminolevulinic acid dehydratase 11 331 2.8E-139 T 13-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 THITH_12105 667dffb92483e7bf79ac50e2a1b867c0 266 Pfam PF10108 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB 47 256 3.2E-83 T 13-10-2018 IPR019288 Predicted 3'-5' exonuclease, PolB-like THITH_12105 667dffb92483e7bf79ac50e2a1b867c0 266 SUPERFAMILY SSF53098 5 222 1.32E-39 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_12105 667dffb92483e7bf79ac50e2a1b867c0 266 Gene3D G3DSA:3.30.420.10 47 214 1.8E-20 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_02185 d2333c568f73e522fdf850cbc04ed200 126 Pfam PF01381 Helix-turn-helix 71 125 1.2E-15 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_02185 d2333c568f73e522fdf850cbc04ed200 126 Gene3D G3DSA:1.10.260.40 68 126 5.3E-18 T 13-10-2018 THITH_02185 d2333c568f73e522fdf850cbc04ed200 126 SUPERFAMILY SSF47413 70 125 7.78E-16 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 THITH_02185 d2333c568f73e522fdf850cbc04ed200 126 SMART SM00530 70 125 2.3E-14 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_00960 ff136928cc399a782482836e27fbf6e1 161 TIGRFAM TIGR00077 lspA: signal peptidase II 7 147 2.5E-38 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 THITH_00960 ff136928cc399a782482836e27fbf6e1 161 Pfam PF01252 Signal peptidase (SPase) II 7 147 1.1E-40 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 THITH_00960 ff136928cc399a782482836e27fbf6e1 161 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 3 154 16.229 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 THITH_00960 ff136928cc399a782482836e27fbf6e1 161 ProSitePatterns PS00855 Signal peptidases II signature. 96 108 - T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 THITH_00960 ff136928cc399a782482836e27fbf6e1 161 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 45 53 1.1E-18 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 THITH_00960 ff136928cc399a782482836e27fbf6e1 161 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 129 145 1.1E-18 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 THITH_00960 ff136928cc399a782482836e27fbf6e1 161 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 93 108 1.1E-18 T 13-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 THITH_05800 b01793e2074b4e30cc8adc986ac7061b 378 Pfam PF13439 Glycosyltransferase Family 4 23 158 2.5E-7 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 THITH_05800 b01793e2074b4e30cc8adc986ac7061b 378 SUPERFAMILY SSF53756 28 371 2.47E-46 T 13-10-2018 THITH_05800 b01793e2074b4e30cc8adc986ac7061b 378 Pfam PF00534 Glycosyl transferases group 1 187 346 4.0E-18 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 THITH_05800 b01793e2074b4e30cc8adc986ac7061b 378 Gene3D G3DSA:3.40.50.2000 16 184 1.9E-7 T 13-10-2018 THITH_05800 b01793e2074b4e30cc8adc986ac7061b 378 Gene3D G3DSA:3.40.50.2000 185 350 7.6E-30 T 13-10-2018 THITH_02355 dd895c308e6a33c0cc225934a6699f56 432 Gene3D G3DSA:3.90.760.10 361 432 2.2E-27 T 13-10-2018 IPR037092 Flavocytochrome c sulphide dehydrogenase, flavin-binding domain superfamily GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 THITH_02355 dd895c308e6a33c0cc225934a6699f56 432 Pfam PF10518 TAT (twin-arginine translocation) pathway signal sequence 3 28 1.1E-5 T 13-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THITH_02355 dd895c308e6a33c0cc225934a6699f56 432 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 23 4.7E-5 T 13-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THITH_02355 dd895c308e6a33c0cc225934a6699f56 432 SUPERFAMILY SSF55424 362 432 1.18E-20 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THITH_02355 dd895c308e6a33c0cc225934a6699f56 432 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 40 152 6.3E-10 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THITH_02355 dd895c308e6a33c0cc225934a6699f56 432 Pfam PF09242 Flavocytochrome c sulphide dehydrogenase, flavin-binding 364 431 1.1E-30 T 13-10-2018 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 THITH_02355 dd895c308e6a33c0cc225934a6699f56 432 Gene3D G3DSA:3.50.50.60 153 288 5.0E-108 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_02355 dd895c308e6a33c0cc225934a6699f56 432 Gene3D G3DSA:3.50.50.60 41 350 5.0E-108 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_02355 dd895c308e6a33c0cc225934a6699f56 432 SUPERFAMILY SSF51905 39 358 2.71E-28 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_02355 dd895c308e6a33c0cc225934a6699f56 432 SUPERFAMILY SSF51905 151 288 1.42E-38 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_00350 373819146c8a5599758449a87937fe29 282 Gene3D G3DSA:3.30.70.1290 1 162 2.5E-41 T 13-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 THITH_00350 373819146c8a5599758449a87937fe29 282 Pfam PF01797 Transposase IS200 like 13 120 2.6E-12 T 13-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THITH_00350 373819146c8a5599758449a87937fe29 282 SUPERFAMILY SSF143422 3 126 3.53E-25 T 13-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 THITH_00350 373819146c8a5599758449a87937fe29 282 SMART SM01321 9 123 5.8E-41 T 13-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THITH_09295 9ba668760ce1faa6736bb5b965981846 624 TIGRFAM TIGR02577 cas_TM1794_Cmr2: CRISPR-associated protein Cas10/Cmr2, subtype III-B 340 474 3.0E-30 T 13-10-2018 IPR013407 CRISPR-associated protein Cmr2 THITH_09295 9ba668760ce1faa6736bb5b965981846 624 Gene3D G3DSA:3.30.70.2230 346 501 1.2E-30 T 13-10-2018 THITH_09295 9ba668760ce1faa6736bb5b965981846 624 Pfam PF12469 CRISPR-associated protein 5 88 3.7E-16 T 13-10-2018 IPR024615 CRISPR-associated protein Cmr2, N-terminal THITH_09295 9ba668760ce1faa6736bb5b965981846 624 Gene3D G3DSA:3.30.70.2220 2 236 1.1E-12 T 13-10-2018 IPR038242 Cmr2, N-terminal domain superfamily THITH_11355 3291171409fe9046a45edc37c4335ec8 265 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 6 259 19.965 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 THITH_11355 3291171409fe9046a45edc37c4335ec8 265 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 138 150 - T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 THITH_11355 3291171409fe9046a45edc37c4335ec8 265 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 9 254 1.1E-80 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 THITH_11355 3291171409fe9046a45edc37c4335ec8 265 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 5 259 9.4E-78 T 13-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 THITH_08540 3544cf8f7bc82d33b2554c3f295bf784 316 Gene3D G3DSA:3.40.50.720 6 299 1.7E-100 T 13-10-2018 THITH_08540 3544cf8f7bc82d33b2554c3f295bf784 316 Gene3D G3DSA:3.90.25.10 166 306 1.7E-100 T 13-10-2018 THITH_08540 3544cf8f7bc82d33b2554c3f295bf784 316 SUPERFAMILY SSF51735 5 297 5.55E-57 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_08540 3544cf8f7bc82d33b2554c3f295bf784 316 Pfam PF05368 NmrA-like family 7 251 3.8E-41 T 13-10-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 THITH_08920 9b9c1e3b547ce4e0295f059895af3194 442 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 336 441 1.6E-12 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_08920 9b9c1e3b547ce4e0295f059895af3194 442 Gene3D G3DSA:1.10.287.130 179 287 1.1E-9 T 13-10-2018 THITH_08920 9b9c1e3b547ce4e0295f059895af3194 442 SUPERFAMILY SSF47384 215 275 1.53E-6 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_08920 9b9c1e3b547ce4e0295f059895af3194 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 384 3.8E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_08920 9b9c1e3b547ce4e0295f059895af3194 442 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 419 3.8E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_08920 9b9c1e3b547ce4e0295f059895af3194 442 SMART SM00387 334 442 2.0E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_08920 9b9c1e3b547ce4e0295f059895af3194 442 SUPERFAMILY SSF55874 298 440 1.31E-25 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_08920 9b9c1e3b547ce4e0295f059895af3194 442 Gene3D G3DSA:3.30.565.10 296 442 4.0E-25 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_12985 03568a6306166a5411000e715d08144e 158 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 5.9E-78 T 13-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12985 03568a6306166a5411000e715d08144e 158 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 42.276 T 13-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12985 03568a6306166a5411000e715d08144e 158 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 145 2.1E-22 T 13-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12985 03568a6306166a5411000e715d08144e 158 SUPERFAMILY SSF56770 9 153 1.96E-67 T 13-10-2018 THITH_12985 03568a6306166a5411000e715d08144e 158 Gene3D G3DSA:3.40.50.12280 2 158 7.3E-80 T 13-10-2018 THITH_12985 03568a6306166a5411000e715d08144e 158 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 13-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_02830 9c0a8c0d0d383f3e97ee27d4c57ee309 351 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 31 338 2.3E-68 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THITH_02830 9c0a8c0d0d383f3e97ee27d4c57ee309 351 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 52 267 2.7E-16 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THITH_02830 9c0a8c0d0d383f3e97ee27d4c57ee309 351 Gene3D G3DSA:2.40.50.100 54 194 1.5E-61 T 13-10-2018 THITH_02830 9c0a8c0d0d383f3e97ee27d4c57ee309 351 SUPERFAMILY SSF111369 46 275 1.96E-28 T 13-10-2018 THITH_02830 9c0a8c0d0d383f3e97ee27d4c57ee309 351 Gene3D G3DSA:1.10.287.470 88 159 1.5E-61 T 13-10-2018 THITH_02830 9c0a8c0d0d383f3e97ee27d4c57ee309 351 Gene3D G3DSA:2.40.420.20 31 332 1.5E-61 T 13-10-2018 THITH_02830 9c0a8c0d0d383f3e97ee27d4c57ee309 351 Gene3D G3DSA:2.40.30.170 42 274 1.5E-61 T 13-10-2018 THITH_12190 56ef7f4b8b766fd3291b88d8415f00dc 189 SMART SM00479 7 180 1.3E-12 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THITH_12190 56ef7f4b8b766fd3291b88d8415f00dc 189 Pfam PF00929 Exonuclease 9 170 9.9E-30 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THITH_12190 56ef7f4b8b766fd3291b88d8415f00dc 189 Gene3D G3DSA:3.30.420.10 1 182 4.6E-68 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_12190 56ef7f4b8b766fd3291b88d8415f00dc 189 Hamap MF_00045 Oligoribonuclease [orn]. 3 181 42.672 T 13-10-2018 IPR022894 Oligoribonuclease GO:0000175 THITH_12190 56ef7f4b8b766fd3291b88d8415f00dc 189 SUPERFAMILY SSF53098 3 180 1.45E-42 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_07160 5189c2f6f3e1523b628d2195aee8a5b7 373 Pfam PF11376 Protein of unknown function (DUF3179) 98 357 7.4E-90 T 13-10-2018 IPR021516 Protein of unknown function DUF3179 THITH_04460 33bd909fda4f3d0b2724dbe9acd9d6cb 141 Pfam PF03334 Na+/H+ antiporter subunit 14 93 3.8E-26 T 13-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 THITH_04460 33bd909fda4f3d0b2724dbe9acd9d6cb 141 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 13 107 5.0E-24 T 13-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 THITH_03225 9ed4534c78a1983a60eafa6cb7fffdcb 333 SMART SM00829 10 326 2.3E-37 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THITH_03225 9ed4534c78a1983a60eafa6cb7fffdcb 333 Pfam PF00107 Zinc-binding dehydrogenase 156 265 3.9E-25 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THITH_03225 9ed4534c78a1983a60eafa6cb7fffdcb 333 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 87 1.7E-6 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THITH_03225 9ed4534c78a1983a60eafa6cb7fffdcb 333 Gene3D G3DSA:3.90.180.10 8 324 1.9E-96 T 13-10-2018 THITH_03225 9ed4534c78a1983a60eafa6cb7fffdcb 333 SUPERFAMILY SSF50129 1 145 8.98E-37 T 13-10-2018 IPR011032 GroES-like superfamily THITH_03225 9ed4534c78a1983a60eafa6cb7fffdcb 333 Gene3D G3DSA:3.40.50.720 125 295 1.9E-96 T 13-10-2018 THITH_03225 9ed4534c78a1983a60eafa6cb7fffdcb 333 SUPERFAMILY SSF51735 117 271 2.03E-44 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 Pfam PF02574 Homocysteine S-methyltransferase 16 324 2.2E-84 T 13-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 Pfam PF02310 B12 binding domain 746 836 2.3E-19 T 13-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 Gene3D G3DSA:3.40.50.280 742 893 5.0E-55 T 13-10-2018 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 Gene3D G3DSA:1.10.1240.10 646 734 9.4E-40 T 13-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 SUPERFAMILY SSF47644 649 736 8.89E-28 T 13-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 958 1230 2.7E-121 T 13-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 Pfam PF02607 B12 binding domain 656 729 1.0E-23 T 13-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 Pfam PF00809 Pterin binding enzyme 359 597 4.0E-61 T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 PIRSF PIRSF000381 1 1217 0.0 T 13-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 Gene3D G3DSA:3.20.20.20 339 642 1.3E-134 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 SUPERFAMILY SSF51717 355 629 3.53E-92 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 Gene3D G3DSA:1.10.288.10 956 1114 3.5E-133 T 13-10-2018 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 SMART SM01018 654 737 7.6E-44 T 13-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 TIGRFAM TIGR02082 metH: methionine synthase 12 1213 0.0 T 13-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 SUPERFAMILY SSF56507 935 1248 1.96E-120 T 13-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 SUPERFAMILY SSF52242 742 891 1.83E-43 T 13-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 Gene3D G3DSA:3.20.20.330 2 337 2.0E-132 T 13-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 Gene3D G3DSA:3.10.196.10 945 1245 3.5E-133 T 13-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_16310 d5ced21b78de72411ae221af6eefb7d3 1254 SUPERFAMILY SSF82282 6 398 4.19E-122 T 13-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 THITH_06805 63a503586995f960cd7a600109da393a 818 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 32 809 2.8E-230 T 13-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 THITH_06805 63a503586995f960cd7a600109da393a 818 Pfam PF07503 HypF finger 185 216 5.6E-16 T 13-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 THITH_06805 63a503586995f960cd7a600109da393a 818 Pfam PF07503 HypF finger 134 166 1.9E-17 T 13-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 THITH_06805 63a503586995f960cd7a600109da393a 818 Pfam PF00708 Acylphosphatase 31 106 9.5E-22 T 13-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THITH_06805 63a503586995f960cd7a600109da393a 818 PIRSF PIRSF006256 26 817 2.7E-286 T 13-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 THITH_06805 63a503586995f960cd7a600109da393a 818 Gene3D G3DSA:3.90.870.50 32 405 2.4E-142 T 13-10-2018 THITH_06805 63a503586995f960cd7a600109da393a 818 SUPERFAMILY SSF55821 201 432 1.16E-39 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily THITH_06805 63a503586995f960cd7a600109da393a 818 Gene3D G3DSA:3.30.420.350 529 797 8.7E-120 T 13-10-2018 THITH_06805 63a503586995f960cd7a600109da393a 818 ProSitePatterns PS00150 Acylphosphatase signature 1. 34 44 - T 13-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THITH_06805 63a503586995f960cd7a600109da393a 818 Gene3D G3DSA:3.30.420.360 426 809 8.7E-120 T 13-10-2018 THITH_06805 63a503586995f960cd7a600109da393a 818 Pfam PF01300 Telomere recombination 236 427 1.3E-44 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 THITH_06805 63a503586995f960cd7a600109da393a 818 SUPERFAMILY SSF54975 28 116 2.16E-24 T 13-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THITH_06805 63a503586995f960cd7a600109da393a 818 Gene3D G3DSA:3.30.110.120 279 414 2.4E-142 T 13-10-2018 THITH_02020 2cb662d5d3ded0170d9036b702818d28 219 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 108 198 1.0E-18 T 13-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 THITH_02020 2cb662d5d3ded0170d9036b702818d28 219 Gene3D G3DSA:2.60.120.620 13 200 2.7E-50 T 13-10-2018 THITH_02020 2cb662d5d3ded0170d9036b702818d28 219 SMART SM00702 19 198 6.4E-23 T 13-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 THITH_13235 ee66a2396ff9032e2509d4c255f8af0a 309 TIGRFAM TIGR04052 AZL_007920_fam: AZL_007920/MXAN_0976 family protein 76 290 2.5E-70 T 13-10-2018 IPR023977 Conserved hypotheical protein CHP04052 THITH_01275 703582a440b158c95b397d2f6184ebb5 67 PIRSF PIRSF002599 1 67 2.5E-23 T 13-10-2018 IPR012156 Cold shock, CspA GO:0003676 THITH_01275 703582a440b158c95b397d2f6184ebb5 67 PRINTS PR00050 Cold shock protein signature 4 19 9.4E-17 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THITH_01275 703582a440b158c95b397d2f6184ebb5 67 PRINTS PR00050 Cold shock protein signature 25 34 9.4E-17 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THITH_01275 703582a440b158c95b397d2f6184ebb5 67 PRINTS PR00050 Cold shock protein signature 40 58 9.4E-17 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THITH_01275 703582a440b158c95b397d2f6184ebb5 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 13-10-2018 IPR019844 Cold-shock conserved site THITH_01275 703582a440b158c95b397d2f6184ebb5 67 Gene3D G3DSA:2.40.50.140 2 67 2.2E-29 T 13-10-2018 THITH_01275 703582a440b158c95b397d2f6184ebb5 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 2.0E-29 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THITH_01275 703582a440b158c95b397d2f6184ebb5 67 SMART SM00357 3 67 5.5E-28 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 THITH_01275 703582a440b158c95b397d2f6184ebb5 67 SUPERFAMILY SSF50249 2 65 1.18E-24 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_08425 9887ab4c92c643dc276d6ac071d707b4 631 TIGRFAM TIGR04244 nitrous_NosZ_RR: nitrous-oxide reductase, TAT-dependent 13 629 2.6E-303 T 13-10-2018 IPR023644 Nitrous-oxide reductase GO:0005507|GO:0005509|GO:0050304|GO:0055114 KEGG: 00910+1.7.2.4|MetaCyc: PWY-6748|MetaCyc: PWY-7084 THITH_08425 9887ab4c92c643dc276d6ac071d707b4 631 SUPERFAMILY SSF49503 502 629 8.35E-35 T 13-10-2018 IPR008972 Cupredoxin THITH_08425 9887ab4c92c643dc276d6ac071d707b4 631 Gene3D G3DSA:2.130.10.10 54 510 8.4E-190 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 THITH_08425 9887ab4c92c643dc276d6ac071d707b4 631 SUPERFAMILY SSF50974 56 498 5.36E-118 T 13-10-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 THITH_08425 9887ab4c92c643dc276d6ac071d707b4 631 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 574 622 - T 13-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_08425 9887ab4c92c643dc276d6ac071d707b4 631 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 13 36 8.3E-4 T 13-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THITH_08425 9887ab4c92c643dc276d6ac071d707b4 631 Gene3D G3DSA:2.60.40.420 511 630 1.5E-34 T 13-10-2018 IPR008972 Cupredoxin THITH_08425 9887ab4c92c643dc276d6ac071d707b4 631 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 571 623 9.6E-6 T 13-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_08425 9887ab4c92c643dc276d6ac071d707b4 631 Hamap MF_00716 Nitrous-oxide reductase [nosZ]. 1 630 56.54 T 13-10-2018 IPR023644 Nitrous-oxide reductase GO:0005507|GO:0005509|GO:0050304|GO:0055114 KEGG: 00910+1.7.2.4|MetaCyc: PWY-6748|MetaCyc: PWY-7084 THITH_06700 9462102c4104bc034e77412ed820188e 250 SUPERFAMILY SSF53955 83 234 2.38E-49 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily THITH_06700 9462102c4104bc034e77412ed820188e 250 Gene3D G3DSA:1.10.530.10 88 238 1.6E-47 T 13-10-2018 THITH_06700 9462102c4104bc034e77412ed820188e 250 Pfam PF01464 Transglycosylase SLT domain 118 224 9.0E-29 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 THITH_06700 9462102c4104bc034e77412ed820188e 250 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 134 162 - T 13-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 THITH_06700 9462102c4104bc034e77412ed820188e 250 Pfam PF13511 Domain of unknown function (DUF4124) 14 57 4.9E-9 T 13-10-2018 IPR025392 Domain of unknown function DUF4124 THITH_07860 d41ceee2793d49df44f1d89eec71a8c6 319 SUPERFAMILY SSF55174 18 68 1.23E-9 T 13-10-2018 THITH_07860 d41ceee2793d49df44f1d89eec71a8c6 319 SUPERFAMILY SSF55120 86 314 5.12E-56 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_07860 d41ceee2793d49df44f1d89eec71a8c6 319 Pfam PF01479 S4 domain 19 65 5.2E-10 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_07860 d41ceee2793d49df44f1d89eec71a8c6 319 Pfam PF00849 RNA pseudouridylate synthase 99 252 1.4E-23 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_07860 d41ceee2793d49df44f1d89eec71a8c6 319 Gene3D G3DSA:3.30.2350.10 91 316 2.1E-63 T 13-10-2018 THITH_07860 d41ceee2793d49df44f1d89eec71a8c6 319 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 16 314 1.1E-66 T 13-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_07860 d41ceee2793d49df44f1d89eec71a8c6 319 SMART SM00363 19 82 1.6E-8 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_07860 d41ceee2793d49df44f1d89eec71a8c6 319 Gene3D G3DSA:3.10.290.10 8 70 9.8E-17 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 THITH_06245 7d0bd1266425212e0643473a7e026539 787 SUPERFAMILY SSF54991 688 786 8.63E-27 T 13-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 THITH_06245 7d0bd1266425212e0643473a7e026539 787 SUPERFAMILY SSF46955 405 475 2.93E-14 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily THITH_06245 7d0bd1266425212e0643473a7e026539 787 Pfam PF03484 tRNA synthetase B5 domain 406 471 5.0E-15 T 13-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 THITH_06245 7d0bd1266425212e0643473a7e026539 787 Pfam PF03147 Ferredoxin-fold anticodon binding domain 693 786 1.1E-24 T 13-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 THITH_06245 7d0bd1266425212e0643473a7e026539 787 Gene3D G3DSA:3.30.56.10 7 179 7.6E-68 T 13-10-2018 THITH_06245 7d0bd1266425212e0643473a7e026539 787 Gene3D G3DSA:3.30.930.10 487 682 6.7E-55 T 13-10-2018 THITH_06245 7d0bd1266425212e0643473a7e026539 787 Gene3D G3DSA:3.30.70.380 694 786 5.6E-26 T 13-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 THITH_06245 7d0bd1266425212e0643473a7e026539 787 SUPERFAMILY SSF56037 196 394 1.73E-64 T 13-10-2018 THITH_06245 7d0bd1266425212e0643473a7e026539 787 SMART SM00874 403 471 1.6E-20 T 13-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 THITH_06245 7d0bd1266425212e0643473a7e026539 787 SMART SM00896 693 786 1.6E-35 T 13-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 THITH_06245 7d0bd1266425212e0643473a7e026539 787 Gene3D G3DSA:3.30.56.10 403 475 2.8E-21 T 13-10-2018 THITH_06245 7d0bd1266425212e0643473a7e026539 787 Pfam PF01588 Putative tRNA binding domain 45 145 5.4E-24 T 13-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 THITH_06245 7d0bd1266425212e0643473a7e026539 787 SMART SM00873 212 385 8.0E-81 T 13-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 THITH_06245 7d0bd1266425212e0643473a7e026539 787 Gene3D G3DSA:2.40.50.140 39 154 7.6E-68 T 13-10-2018 THITH_06245 7d0bd1266425212e0643473a7e026539 787 Gene3D G3DSA:3.50.40.10 198 395 1.2E-68 T 13-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 THITH_06245 7d0bd1266425212e0643473a7e026539 787 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 780 41.689 T 13-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 THITH_06245 7d0bd1266425212e0643473a7e026539 787 SUPERFAMILY SSF50249 35 196 2.28E-49 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_06245 7d0bd1266425212e0643473a7e026539 787 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 785 9.3E-226 T 13-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 THITH_06245 7d0bd1266425212e0643473a7e026539 787 Pfam PF03483 B3/4 domain 212 385 9.6E-60 T 13-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 THITH_06245 7d0bd1266425212e0643473a7e026539 787 SUPERFAMILY SSF55681 467 680 5.47E-47 T 13-10-2018 THITH_08305 a4cf88b55ca669086a14b01f647f1db8 1082 Gene3D G3DSA:3.40.50.10810 313 545 3.5E-50 T 13-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily THITH_08305 a4cf88b55ca669086a14b01f647f1db8 1082 SUPERFAMILY SSF52540 449 779 3.09E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_08305 a4cf88b55ca669086a14b01f647f1db8 1082 Gene3D G3DSA:3.40.50.300 556 811 6.9E-55 T 13-10-2018 THITH_08305 a4cf88b55ca669086a14b01f647f1db8 1082 SMART SM00487 334 515 4.1E-27 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_08305 a4cf88b55ca669086a14b01f647f1db8 1082 SMART SM00490 658 740 6.4E-23 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_08305 a4cf88b55ca669086a14b01f647f1db8 1082 SUPERFAMILY SSF52540 332 546 7.55E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_08305 a4cf88b55ca669086a14b01f647f1db8 1082 Pfam PF04434 SWIM zinc finger 102 116 0.96 T 13-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 THITH_08305 a4cf88b55ca669086a14b01f647f1db8 1082 Pfam PF04434 SWIM zinc finger 191 214 0.2 T 13-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 THITH_08305 a4cf88b55ca669086a14b01f647f1db8 1082 Pfam PF00176 SNF2 family N-terminal domain 356 617 9.4E-34 T 13-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 THITH_08305 a4cf88b55ca669086a14b01f647f1db8 1082 Pfam PF00271 Helicase conserved C-terminal domain 632 740 1.3E-17 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_10295 2bb2155a1f9b2b91fa6cc0d9a61fafbd 518 Gene3D G3DSA:3.60.40.10 252 517 1.1E-54 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THITH_10295 2bb2155a1f9b2b91fa6cc0d9a61fafbd 518 SMART SM00331 287 517 2.6E-43 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THITH_10295 2bb2155a1f9b2b91fa6cc0d9a61fafbd 518 SUPERFAMILY SSF81606 299 516 6.8E-6 T 13-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THITH_10295 2bb2155a1f9b2b91fa6cc0d9a61fafbd 518 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 314 516 1.0E-36 T 13-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 THITH_17390 7c8d33b0bd15a5e687eff4a255cba0d3 938 Gene3D G3DSA:3.40.50.11610 715 922 1.1E-163 T 13-10-2018 THITH_17390 7c8d33b0bd15a5e687eff4a255cba0d3 938 Gene3D G3DSA:3.40.50.970 155 512 9.3E-145 T 13-10-2018 THITH_17390 7c8d33b0bd15a5e687eff4a255cba0d3 938 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 25 55 2.3E-7 T 13-10-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 THITH_17390 7c8d33b0bd15a5e687eff4a255cba0d3 938 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 24 922 0.0 T 13-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 THITH_17390 7c8d33b0bd15a5e687eff4a255cba0d3 938 PIRSF PIRSF000157 7 927 0.0 T 13-10-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 THITH_17390 7c8d33b0bd15a5e687eff4a255cba0d3 938 Pfam PF00676 Dehydrogenase E1 component 203 504 1.8E-53 T 13-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 THITH_17390 7c8d33b0bd15a5e687eff4a255cba0d3 938 SUPERFAMILY SSF52518 567 785 1.57E-54 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold THITH_17390 7c8d33b0bd15a5e687eff4a255cba0d3 938 SMART SM00861 585 778 2.1E-61 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THITH_17390 7c8d33b0bd15a5e687eff4a255cba0d3 938 Pfam PF02779 Transketolase, pyrimidine binding domain 584 779 2.0E-67 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THITH_17390 7c8d33b0bd15a5e687eff4a255cba0d3 938 SUPERFAMILY SSF52518 112 525 7.23E-87 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold THITH_17390 7c8d33b0bd15a5e687eff4a255cba0d3 938 Gene3D G3DSA:1.10.287.1150 74 154 1.1E-15 T 13-10-2018 THITH_17390 7c8d33b0bd15a5e687eff4a255cba0d3 938 Gene3D G3DSA:3.40.50.12470 548 794 1.1E-163 T 13-10-2018 THITH_17390 7c8d33b0bd15a5e687eff4a255cba0d3 938 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 783 925 9.8E-42 T 13-10-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 THITH_06395 d2ad54fc77f1679c5c90ace8ac661a0a 517 Pfam PF13649 Methyltransferase domain 45 142 1.7E-9 T 13-10-2018 THITH_06395 d2ad54fc77f1679c5c90ace8ac661a0a 517 Pfam PF10119 Predicted methyltransferase regulatory domain 214 295 7.9E-25 T 13-10-2018 IPR018773 Methyltransferase regulatory domain, predicted THITH_06395 d2ad54fc77f1679c5c90ace8ac661a0a 517 Gene3D G3DSA:3.40.50.150 25 250 1.9E-21 T 13-10-2018 THITH_06395 d2ad54fc77f1679c5c90ace8ac661a0a 517 SUPERFAMILY SSF53335 26 172 1.4E-25 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_15410 f566bb949aa3855f3b3a198adde7a852 314 Gene3D G3DSA:1.10.10.10 1 82 4.4E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_15410 f566bb949aa3855f3b3a198adde7a852 314 SUPERFAMILY SSF46785 1 112 2.44E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_15410 f566bb949aa3855f3b3a198adde7a852 314 Pfam PF03466 LysR substrate binding domain 90 295 3.1E-45 T 13-10-2018 IPR005119 LysR, substrate-binding THITH_15410 f566bb949aa3855f3b3a198adde7a852 314 Gene3D G3DSA:3.40.190.10 167 267 1.3E-79 T 13-10-2018 THITH_15410 f566bb949aa3855f3b3a198adde7a852 314 Gene3D G3DSA:3.40.190.10 93 297 1.3E-79 T 13-10-2018 THITH_15410 f566bb949aa3855f3b3a198adde7a852 314 SUPERFAMILY SSF53850 90 299 5.2E-45 T 13-10-2018 THITH_15410 f566bb949aa3855f3b3a198adde7a852 314 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 64 7.0E-20 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_15410 f566bb949aa3855f3b3a198adde7a852 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 1.1E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_15410 f566bb949aa3855f3b3a198adde7a852 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 1.1E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_15410 f566bb949aa3855f3b3a198adde7a852 314 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 1.1E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_13250 c18dcfb82999187ba2ef18d82ae393b9 134 Pfam PF02472 Biopolymer transport protein ExbD/TolR 12 132 7.6E-25 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 THITH_13250 c18dcfb82999187ba2ef18d82ae393b9 134 Gene3D G3DSA:3.30.420.270 58 129 9.2E-8 T 13-10-2018 THITH_09450 b523ad0ce4aed0e3f97adc184b901abe 350 Gene3D G3DSA:3.30.70.1630 44 216 2.5E-33 T 13-10-2018 THITH_09450 b523ad0ce4aed0e3f97adc184b901abe 350 PIRSF PIRSF006487 2 313 2.7E-15 T 13-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 THITH_09450 b523ad0ce4aed0e3f97adc184b901abe 350 SUPERFAMILY SSF103025 24 265 5.34E-60 T 13-10-2018 THITH_09450 b523ad0ce4aed0e3f97adc184b901abe 350 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 210 274 8.6E-30 T 13-10-2018 IPR017703 YgfZ/GcvT conserved site THITH_09450 b523ad0ce4aed0e3f97adc184b901abe 350 Pfam PF01571 Aminomethyltransferase folate-binding domain 25 239 8.3E-17 T 13-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain THITH_09450 b523ad0ce4aed0e3f97adc184b901abe 350 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 249 303 1.3E-4 T 13-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THITH_09450 b523ad0ce4aed0e3f97adc184b901abe 350 SUPERFAMILY SSF101790 267 346 4.97E-9 T 13-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal THITH_09450 b523ad0ce4aed0e3f97adc184b901abe 350 Gene3D G3DSA:3.30.70.1400 47 134 2.5E-33 T 13-10-2018 THITH_09450 b523ad0ce4aed0e3f97adc184b901abe 350 Gene3D G3DSA:2.40.30.160 219 329 3.9E-36 T 13-10-2018 THITH_10975 a969f7d130dff82e6f4c08d4a3a17063 238 TIGRFAM TIGR02292 ygfB_yecA: yecA family protein 12 191 2.7E-24 T 13-10-2018 IPR011978 Uncharacterised protein family UPF0149 THITH_10975 a969f7d130dff82e6f4c08d4a3a17063 238 Pfam PF03695 Uncharacterised protein family (UPF0149) 14 192 2.9E-31 T 13-10-2018 IPR011978 Uncharacterised protein family UPF0149 THITH_10975 a969f7d130dff82e6f4c08d4a3a17063 238 Pfam PF02810 SEC-C motif 215 232 6.4E-11 T 13-10-2018 IPR004027 SEC-C motif THITH_10975 a969f7d130dff82e6f4c08d4a3a17063 238 SUPERFAMILY SSF101327 12 168 6.15E-15 T 13-10-2018 IPR036255 YgfB-like superfamily THITH_10975 a969f7d130dff82e6f4c08d4a3a17063 238 Gene3D G3DSA:3.10.450.50 177 234 2.5E-11 T 13-10-2018 THITH_10975 a969f7d130dff82e6f4c08d4a3a17063 238 SUPERFAMILY SSF103642 212 233 2.29E-8 T 13-10-2018 THITH_06935 d23d22e4496eddf6d8a6b596ca81dcc6 146 SUPERFAMILY SSF75169 32 145 1.65E-17 T 13-10-2018 IPR027396 DsrEFH-like THITH_06935 d23d22e4496eddf6d8a6b596ca81dcc6 146 Gene3D G3DSA:3.40.1260.10 29 146 3.7E-22 T 13-10-2018 IPR027396 DsrEFH-like THITH_06935 d23d22e4496eddf6d8a6b596ca81dcc6 146 Pfam PF02635 DsrE/DsrF-like family 50 144 1.3E-4 T 13-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THITH_17110 7640e802743006cec9f37dca4ea8f721 477 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 225 240 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THITH_17110 7640e802743006cec9f37dca4ea8f721 477 Gene3D G3DSA:3.40.50.2300 1 130 1.4E-34 T 13-10-2018 THITH_17110 7640e802743006cec9f37dca4ea8f721 477 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 163 176 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THITH_17110 7640e802743006cec9f37dca4ea8f721 477 Pfam PF02954 Bacterial regulatory protein, Fis family 430 469 1.5E-14 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_17110 7640e802743006cec9f37dca4ea8f721 477 Pfam PF00072 Response regulator receiver domain 5 114 3.3E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_17110 7640e802743006cec9f37dca4ea8f721 477 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 435 452 5.8E-9 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_17110 7640e802743006cec9f37dca4ea8f721 477 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 452 472 5.8E-9 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_17110 7640e802743006cec9f37dca4ea8f721 477 Gene3D G3DSA:3.40.50.300 132 310 1.2E-64 T 13-10-2018 THITH_17110 7640e802743006cec9f37dca4ea8f721 477 Gene3D G3DSA:1.10.8.60 311 382 1.2E-18 T 13-10-2018 THITH_17110 7640e802743006cec9f37dca4ea8f721 477 TIGRFAM TIGR01818 ntrC: nitrogen regulation protein NR(I) 5 469 3.2E-217 T 13-10-2018 IPR010114 DNA-binding transcriptional regulator NtrC GO:0000156|GO:0000160|GO:0003677|GO:0005524|GO:0006808 THITH_17110 7640e802743006cec9f37dca4ea8f721 477 SUPERFAMILY SSF52172 3 184 2.85E-39 T 13-10-2018 IPR011006 CheY-like superfamily THITH_17110 7640e802743006cec9f37dca4ea8f721 477 SUPERFAMILY SSF46689 379 472 1.48E-18 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_17110 7640e802743006cec9f37dca4ea8f721 477 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 352 361 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site THITH_17110 7640e802743006cec9f37dca4ea8f721 477 Gene3D G3DSA:1.10.10.60 383 472 1.5E-22 T 13-10-2018 THITH_17110 7640e802743006cec9f37dca4ea8f721 477 SMART SM00382 159 302 2.2E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_17110 7640e802743006cec9f37dca4ea8f721 477 SUPERFAMILY SSF52540 139 382 4.49E-71 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_17110 7640e802743006cec9f37dca4ea8f721 477 SMART SM00448 3 115 2.4E-33 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_17110 7640e802743006cec9f37dca4ea8f721 477 Pfam PF00158 Sigma-54 interaction domain 139 306 1.4E-69 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THITH_16670 8556d96467e9b7a894f28659e5849c7c 461 Gene3D G3DSA:1.10.1740.10 19 99 3.1E-9 T 13-10-2018 THITH_16670 8556d96467e9b7a894f28659e5849c7c 461 Pfam PF04542 Sigma-70 region 2 37 97 1.9E-11 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 THITH_16670 8556d96467e9b7a894f28659e5849c7c 461 SUPERFAMILY SSF88659 126 186 2.4E-7 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like THITH_16670 8556d96467e9b7a894f28659e5849c7c 461 SUPERFAMILY SSF88946 26 101 6.67E-13 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 THITH_01200 fdeef11275af030e59e93b7bed9bdae4 612 SUPERFAMILY SSF116726 322 404 1.57E-16 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_01200 fdeef11275af030e59e93b7bed9bdae4 612 Pfam PF03600 Citrate transporter 22 560 1.7E-50 T 13-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 THITH_01200 fdeef11275af030e59e93b7bed9bdae4 612 Pfam PF02080 TrkA-C domain 329 396 3.0E-9 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THITH_01200 fdeef11275af030e59e93b7bed9bdae4 612 Gene3D G3DSA:3.30.70.1450 326 400 1.1E-15 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_01200 fdeef11275af030e59e93b7bed9bdae4 612 Gene3D G3DSA:3.30.70.1450 236 308 2.1E-8 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_01200 fdeef11275af030e59e93b7bed9bdae4 612 SUPERFAMILY SSF116726 233 308 3.53E-10 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_11660 df6bcb0962c9850a9abb3f153b2d2267 284 SUPERFAMILY SSF56300 6 245 4.46E-31 T 13-10-2018 THITH_11660 df6bcb0962c9850a9abb3f153b2d2267 284 Pfam PF00149 Calcineurin-like phosphoesterase 7 206 2.9E-10 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THITH_11660 df6bcb0962c9850a9abb3f153b2d2267 284 Gene3D G3DSA:3.60.21.10 6 247 5.1E-17 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like THITH_09385 ed78d88cc72274b82dd0a3a133d3350f 163 Hamap MF_01114 Regulatory protein RecX [recX]. 11 159 12.13 T 13-10-2018 IPR003783 Regulatory protein RecX GO:0006282 THITH_09385 ed78d88cc72274b82dd0a3a133d3350f 163 Gene3D G3DSA:1.10.10.10 63 107 6.6E-13 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_09385 ed78d88cc72274b82dd0a3a133d3350f 163 Gene3D G3DSA:1.10.10.10 14 59 7.4E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_09385 ed78d88cc72274b82dd0a3a133d3350f 163 Gene3D G3DSA:1.10.10.10 108 150 4.6E-8 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_09385 ed78d88cc72274b82dd0a3a133d3350f 163 Pfam PF02631 RecX family 38 154 2.1E-24 T 13-10-2018 IPR003783 Regulatory protein RecX GO:0006282 THITH_04120 a6ab7cffd971a15f4b6178cb37aae9db 554 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 161 185 2.2E-9 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04120 a6ab7cffd971a15f4b6178cb37aae9db 554 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 317 336 2.2E-9 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04120 a6ab7cffd971a15f4b6178cb37aae9db 554 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 226 250 2.2E-9 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04120 a6ab7cffd971a15f4b6178cb37aae9db 554 Pfam PF00361 Proton-conducting membrane transporter 125 345 1.6E-32 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_11780 d7149428122a414fd8f05a1bd8bd296d 306 PIRSF PIRSF006232 20 300 3.8E-83 T 13-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 THITH_11780 d7149428122a414fd8f05a1bd8bd296d 306 Gene3D G3DSA:2.60.120.10 164 262 1.7E-66 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_11780 d7149428122a414fd8f05a1bd8bd296d 306 Gene3D G3DSA:2.60.120.10 36 287 1.7E-66 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_11780 d7149428122a414fd8f05a1bd8bd296d 306 SUPERFAMILY SSF51182 27 304 2.8E-76 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily THITH_11780 d7149428122a414fd8f05a1bd8bd296d 306 Pfam PF05726 Pirin C-terminal cupin domain 195 289 3.2E-19 T 13-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 THITH_11780 d7149428122a414fd8f05a1bd8bd296d 306 Pfam PF02678 Pirin 37 142 2.3E-31 T 13-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 THITH_13820 8bff745c0515a8e63c906926687f8922 205 Pfam PF00027 Cyclic nucleotide-binding domain 24 104 4.2E-11 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain THITH_13820 8bff745c0515a8e63c906926687f8922 205 Gene3D G3DSA:1.10.10.10 135 205 4.3E-7 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_13820 8bff745c0515a8e63c906926687f8922 205 Gene3D G3DSA:2.60.120.10 24 133 2.7E-22 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_13820 8bff745c0515a8e63c906926687f8922 205 Pfam PF13545 Crp-like helix-turn-helix domain 142 193 5.5E-7 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THITH_13820 8bff745c0515a8e63c906926687f8922 205 SUPERFAMILY SSF51206 3 129 7.2E-17 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like THITH_13820 8bff745c0515a8e63c906926687f8922 205 SUPERFAMILY SSF46785 137 195 5.65E-7 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_13820 8bff745c0515a8e63c906926687f8922 205 SMART SM00100 2 123 1.2E-5 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain THITH_13460 371e6bbd846b517fb86f2ae984776911 296 Gene3D G3DSA:3.40.50.300 1 278 2.5E-96 T 13-10-2018 THITH_13460 371e6bbd846b517fb86f2ae984776911 296 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 1 280 3.0E-92 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 THITH_13460 371e6bbd846b517fb86f2ae984776911 296 Pfam PF01715 IPP transferase 30 275 7.2E-79 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 THITH_13460 371e6bbd846b517fb86f2ae984776911 296 SUPERFAMILY SSF52540 1 243 8.62E-8 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13460 371e6bbd846b517fb86f2ae984776911 296 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 1 292 27.005 T 13-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 THITH_13460 371e6bbd846b517fb86f2ae984776911 296 Gene3D G3DSA:1.10.20.140 104 175 2.5E-96 T 13-10-2018 THITH_13460 371e6bbd846b517fb86f2ae984776911 296 SUPERFAMILY SSF52540 1 141 2.73E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_04940 bad9beb22ca407f0253b75f02a395566 317 Gene3D G3DSA:3.50.50.60 118 244 1.6E-122 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_04940 bad9beb22ca407f0253b75f02a395566 317 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 302 8.9E-47 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THITH_04940 bad9beb22ca407f0253b75f02a395566 317 SUPERFAMILY SSF51905 1 313 6.01E-52 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_04940 bad9beb22ca407f0253b75f02a395566 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 6.8E-77 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THITH_04940 bad9beb22ca407f0253b75f02a395566 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 6.8E-77 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THITH_04940 bad9beb22ca407f0253b75f02a395566 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 6.8E-77 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THITH_04940 bad9beb22ca407f0253b75f02a395566 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 6.8E-77 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THITH_04940 bad9beb22ca407f0253b75f02a395566 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 6.8E-77 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THITH_04940 bad9beb22ca407f0253b75f02a395566 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 199 215 6.8E-77 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THITH_04940 bad9beb22ca407f0253b75f02a395566 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 238 259 6.8E-77 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THITH_04940 bad9beb22ca407f0253b75f02a395566 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 6.8E-77 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THITH_04940 bad9beb22ca407f0253b75f02a395566 317 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 6.8E-77 T 13-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 THITH_04940 bad9beb22ca407f0253b75f02a395566 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 5.7E-39 T 13-10-2018 THITH_04940 bad9beb22ca407f0253b75f02a395566 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 5.7E-39 T 13-10-2018 THITH_04940 bad9beb22ca407f0253b75f02a395566 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 5.7E-39 T 13-10-2018 THITH_04940 bad9beb22ca407f0253b75f02a395566 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 5.7E-39 T 13-10-2018 THITH_04940 bad9beb22ca407f0253b75f02a395566 317 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 5.7E-39 T 13-10-2018 THITH_04940 bad9beb22ca407f0253b75f02a395566 317 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 9 313 1.8E-118 T 13-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 THITH_04940 bad9beb22ca407f0253b75f02a395566 317 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 136 156 - T 13-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 THITH_04940 bad9beb22ca407f0253b75f02a395566 317 Gene3D G3DSA:3.50.50.60 10 311 1.6E-122 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 Pfam PF08264 Anticodon-binding domain of tRNA 700 824 1.0E-18 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 417 570 8.6E-7 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 171 9.2E-28 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 53 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 Gene3D G3DSA:3.10.330.110 567 628 0.0 T 13-10-2018 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 Gene3D G3DSA:3.90.740.10 227 413 0.0 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 Gene3D G3DSA:3.10.20.590 799 861 1.7E-22 T 13-10-2018 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 4 860 23.801 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 Gene3D G3DSA:3.40.50.620 33 566 0.0 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 SUPERFAMILY SSF47323 662 860 2.8E-38 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 SUPERFAMILY SSF50677 226 414 4.29E-53 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 5 861 0.0 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 221 402 6.8E-71 T 13-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 SUPERFAMILY SSF52374 5 668 5.63E-150 T 13-10-2018 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 Gene3D G3DSA:1.10.730.10 9 792 0.0 T 13-10-2018 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 PRINTS PR00985 Leucyl-tRNA synthetase signature 486 504 7.0E-53 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 PRINTS PR00985 Leucyl-tRNA synthetase signature 127 144 7.0E-53 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 PRINTS PR00985 Leucyl-tRNA synthetase signature 185 198 7.0E-53 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 PRINTS PR00985 Leucyl-tRNA synthetase signature 215 234 7.0E-53 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 PRINTS PR00985 Leucyl-tRNA synthetase signature 153 169 7.0E-53 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 7.0E-53 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THITH_14060 98f07dbdf1c18c44f722674997cf7394 863 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 7.0E-53 T 13-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 THITH_13915 ad4d2da1a386457491b4e38f28f5cc1c 31 Pfam PF10636 Hemin uptake protein hemP 1 31 2.0E-15 T 13-10-2018 IPR019600 Hemin uptake protein HemP THITH_13915 ad4d2da1a386457491b4e38f28f5cc1c 31 Gene3D G3DSA:2.10.70.10 1 31 9.5E-13 T 13-10-2018 THITH_13620 3de8ad139bf2bd0f3029f9e6eb424b3a 284 SUPERFAMILY SSF52374 1 284 3.49E-97 T 13-10-2018 THITH_13620 3de8ad139bf2bd0f3029f9e6eb424b3a 284 Hamap MF_00158 Pantothenate synthetase [panC]. 2 284 38.152 T 13-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 THITH_13620 3de8ad139bf2bd0f3029f9e6eb424b3a 284 Gene3D G3DSA:3.30.1300.10 179 284 1.5E-25 T 13-10-2018 THITH_13620 3de8ad139bf2bd0f3029f9e6eb424b3a 284 Pfam PF02569 Pantoate-beta-alanine ligase 3 282 1.3E-98 T 13-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 THITH_13620 3de8ad139bf2bd0f3029f9e6eb424b3a 284 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 27 66 3.2E-8 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THITH_13620 3de8ad139bf2bd0f3029f9e6eb424b3a 284 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 8 282 3.5E-86 T 13-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 THITH_13620 3de8ad139bf2bd0f3029f9e6eb424b3a 284 Gene3D G3DSA:3.40.50.620 1 178 6.5E-72 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_10600 484ce16040804bb8c941ba9210ad9d29 660 Gene3D G3DSA:1.10.472.70 558 650 8.7E-33 T 13-10-2018 THITH_10600 484ce16040804bb8c941ba9210ad9d29 660 SUPERFAMILY SSF46977 462 655 5.49E-51 T 13-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_10600 484ce16040804bb8c941ba9210ad9d29 660 Pfam PF00890 FAD binding domain 7 411 3.2E-121 T 13-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_10600 484ce16040804bb8c941ba9210ad9d29 660 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 600 1.9E-214 T 13-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_10600 484ce16040804bb8c941ba9210ad9d29 660 SUPERFAMILY SSF56425 251 370 3.59E-39 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_10600 484ce16040804bb8c941ba9210ad9d29 660 Gene3D G3DSA:1.20.58.100 441 557 1.8E-34 T 13-10-2018 THITH_10600 484ce16040804bb8c941ba9210ad9d29 660 Pfam PF02910 Fumarate reductase flavoprotein C-term 470 600 3.5E-36 T 13-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_10600 484ce16040804bb8c941ba9210ad9d29 660 Gene3D G3DSA:3.50.50.60 7 421 1.4E-144 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_10600 484ce16040804bb8c941ba9210ad9d29 660 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 41 50 - T 13-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_10600 484ce16040804bb8c941ba9210ad9d29 660 Gene3D G3DSA:3.90.700.10 277 384 1.4E-144 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_10600 484ce16040804bb8c941ba9210ad9d29 660 SUPERFAMILY SSF51905 3 430 1.56E-56 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 Pfam PF00575 S1 RNA binding domain 641 722 4.7E-16 T 13-10-2018 IPR003029 S1 domain GO:0003676 THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 SUPERFAMILY SSF50249 228 641 5.03E-143 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 Hamap MF_01895 Ribonuclease R [rnr]. 46 725 56.926 T 13-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 Pfam PF00773 RNB domain 268 595 5.2E-104 T 13-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 SMART SM00316 642 725 5.4E-16 T 13-10-2018 IPR022967 RNA-binding domain, S1 THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 Gene3D G3DSA:2.40.50.140 86 156 1.2E-17 T 13-10-2018 THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 88 725 1.5E-223 T 13-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 SUPERFAMILY SSF50249 644 724 2.91E-21 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 SMART SM00357 94 153 8.8E-12 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 SMART SM00357 158 222 4.4 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 SUPERFAMILY SSF50249 146 244 2.57E-15 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 Gene3D G3DSA:2.40.50.140 645 745 3.1E-22 T 13-10-2018 THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 ProSitePatterns PS01175 Ribonuclease II family signature. 563 587 - T 13-10-2018 IPR022966 Ribonuclease II/R, conserved site THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 TIGRFAM TIGR02063 RNase_R: ribonuclease R 27 725 1.1E-256 T 13-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 SUPERFAMILY SSF50249 75 155 5.08E-19 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 Pfam PF08206 Ribonuclease B OB domain 95 152 1.0E-20 T 13-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 Pfam PF08461 Ribonuclease R winged-helix domain 31 82 3.1E-8 T 13-10-2018 IPR013668 Ribonuclease R winged-helix domain THITH_03530 8b4b23183673e263abcd57df1e8e7618 951 SMART SM00955 268 596 4.5E-179 T 13-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 THITH_16775 c548a9c012cb394b04460cdb41b485f8 87 Gene3D G3DSA:2.10.260.10 4 87 9.9E-18 T 13-10-2018 THITH_16775 c548a9c012cb394b04460cdb41b485f8 87 SUPERFAMILY SSF89447 5 62 1.46E-9 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily THITH_16775 c548a9c012cb394b04460cdb41b485f8 87 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 11 42 1.1E-6 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THITH_02000 c2c0e85a4a87c0754f7a3a85856e8a31 376 SUPERFAMILY SSF51735 138 313 6.82E-38 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_02000 c2c0e85a4a87c0754f7a3a85856e8a31 376 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 142 364 4.1E-68 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain THITH_02000 c2c0e85a4a87c0754f7a3a85856e8a31 376 SUPERFAMILY SSF52283 5 169 1.11E-40 T 13-10-2018 THITH_02000 c2c0e85a4a87c0754f7a3a85856e8a31 376 SMART SM01002 147 309 3.2E-79 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain THITH_02000 c2c0e85a4a87c0754f7a3a85856e8a31 376 Gene3D G3DSA:3.40.50.720 138 316 1.7E-135 T 13-10-2018 THITH_02000 c2c0e85a4a87c0754f7a3a85856e8a31 376 SMART SM01003 6 138 4.8E-53 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal THITH_02000 c2c0e85a4a87c0754f7a3a85856e8a31 376 Gene3D G3DSA:3.40.50.720 6 361 1.7E-135 T 13-10-2018 THITH_02000 c2c0e85a4a87c0754f7a3a85856e8a31 376 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 7 138 1.3E-37 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal THITH_02000 c2c0e85a4a87c0754f7a3a85856e8a31 376 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 171 196 - T 13-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 THITH_11025 d6d8417f8890f7c9f723a01b70c76ec2 514 Pfam PF02810 SEC-C motif 494 511 6.4E-10 T 13-10-2018 IPR004027 SEC-C motif THITH_11025 d6d8417f8890f7c9f723a01b70c76ec2 514 Gene3D G3DSA:3.10.450.50 476 512 4.8E-9 T 13-10-2018 THITH_11025 d6d8417f8890f7c9f723a01b70c76ec2 514 SUPERFAMILY SSF103642 492 512 1.49E-7 T 13-10-2018 THITH_11025 d6d8417f8890f7c9f723a01b70c76ec2 514 SUPERFAMILY SSF101327 17 124 3.66E-10 T 13-10-2018 IPR036255 YgfB-like superfamily THITH_11025 d6d8417f8890f7c9f723a01b70c76ec2 514 Pfam PF03695 Uncharacterised protein family (UPF0149) 14 166 6.3E-10 T 13-10-2018 IPR011978 Uncharacterised protein family UPF0149 THITH_02085 078943e755bc246b69ade1faa6a6e92c 422 Gene3D G3DSA:3.40.980.10 38 342 2.6E-143 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily THITH_02085 078943e755bc246b69ade1faa6a6e92c 422 Gene3D G3DSA:3.90.105.10 39 189 2.6E-143 T 13-10-2018 THITH_02085 078943e755bc246b69ade1faa6a6e92c 422 Pfam PF03454 MoeA C-terminal region (domain IV) 347 418 4.4E-20 T 13-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_02085 078943e755bc246b69ade1faa6a6e92c 422 SMART SM00852 195 333 1.1E-43 T 13-10-2018 IPR001453 MoaB/Mog domain THITH_02085 078943e755bc246b69ade1faa6a6e92c 422 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 192 329 3.0E-33 T 13-10-2018 IPR001453 MoaB/Mog domain THITH_02085 078943e755bc246b69ade1faa6a6e92c 422 Gene3D G3DSA:2.170.190.11 63 156 2.6E-143 T 13-10-2018 THITH_02085 078943e755bc246b69ade1faa6a6e92c 422 Pfam PF00994 Probable molybdopterin binding domain 196 332 6.5E-30 T 13-10-2018 IPR001453 MoaB/Mog domain THITH_02085 078943e755bc246b69ade1faa6a6e92c 422 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 268 301 - T 13-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 THITH_02085 078943e755bc246b69ade1faa6a6e92c 422 SUPERFAMILY SSF63867 343 419 2.62E-23 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_02085 078943e755bc246b69ade1faa6a6e92c 422 Gene3D G3DSA:2.40.340.10 343 413 2.6E-143 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_02085 078943e755bc246b69ade1faa6a6e92c 422 SUPERFAMILY SSF63882 19 191 7.98E-55 T 13-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_02085 078943e755bc246b69ade1faa6a6e92c 422 Pfam PF03453 MoeA N-terminal region (domain I and II) 23 182 4.1E-46 T 13-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_02085 078943e755bc246b69ade1faa6a6e92c 422 SUPERFAMILY SSF53218 192 336 1.44E-43 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 Gene3D G3DSA:3.40.50.800 533 637 1.1E-29 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 SMART SM00863 169 218 1.2E-26 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 Pfam PF03129 Anticodon binding domain 542 630 4.1E-21 T 13-10-2018 IPR004154 Anticodon-binding THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 72 632 2.9E-230 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 Gene3D G3DSA:3.10.20.30 3 63 8.0E-24 T 13-10-2018 IPR012675 Beta-grasp domain superfamily THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 535 547 2.5E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 330 358 2.5E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 465 493 2.5E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 363 386 2.5E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 PRINTS PR01047 Threonyl-tRNA synthetase signature 508 521 2.5E-53 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 SUPERFAMILY SSF55186 64 239 3.4E-69 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 Gene3D G3DSA:3.30.980.10 69 221 8.5E-68 T 13-10-2018 THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 Pfam PF02824 TGS domain 4 61 9.1E-12 T 13-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 SUPERFAMILY SSF55681 242 527 1.91E-94 T 13-10-2018 THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 322 530 8.8E-40 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 66 635 35.535 T 13-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 SUPERFAMILY SSF52954 530 635 5.13E-32 T 13-10-2018 THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 SUPERFAMILY SSF81271 4 61 2.4E-16 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 169 218 1.4E-16 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 Gene3D G3DSA:3.30.54.20 130 186 8.5E-68 T 13-10-2018 THITH_06220 949032f8adcc842b8b43958ef1d700ba 638 Gene3D G3DSA:3.30.930.10 222 532 1.1E-124 T 13-10-2018 THITH_14920 9d14e601074e3aaf9283927b6fa99290 71 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 13-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14920 9d14e601074e3aaf9283927b6fa99290 71 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 2 59 5.5E-24 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14920 9d14e601074e3aaf9283927b6fa99290 71 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 21.588 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14920 9d14e601074e3aaf9283927b6fa99290 71 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 2.4E-16 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14920 9d14e601074e3aaf9283927b6fa99290 71 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 2.4E-16 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14920 9d14e601074e3aaf9283927b6fa99290 71 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 2.4E-16 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14920 9d14e601074e3aaf9283927b6fa99290 71 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 2.4E-16 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14920 9d14e601074e3aaf9283927b6fa99290 71 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 15 44 1.0E-8 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14920 9d14e601074e3aaf9283927b6fa99290 71 Pfam PF01165 Ribosomal protein S21 3 56 3.9E-22 T 13-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14920 9d14e601074e3aaf9283927b6fa99290 71 Gene3D G3DSA:1.20.5.1150 16 54 5.1E-21 T 13-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 192 205 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 SUPERFAMILY SSF53067 187 382 2.59E-67 T 13-10-2018 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 SUPERFAMILY SSF53067 4 184 8.42E-66 T 13-10-2018 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 603 9.2E-291 T 13-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 Gene3D G3DSA:1.20.1270.10 524 603 7.4E-25 T 13-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 337 351 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 SUPERFAMILY SSF100920 384 540 3.79E-61 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 SUPERFAMILY SSF100934 507 605 8.37E-22 T 13-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 Gene3D G3DSA:3.30.420.40 180 366 9.0E-167 T 13-10-2018 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 Gene3D G3DSA:3.90.640.10 229 316 9.0E-167 T 13-10-2018 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 PRINTS PR00301 70kDa heat shock protein signature 365 385 2.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 PRINTS PR00301 70kDa heat shock protein signature 198 208 2.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 PRINTS PR00301 70kDa heat shock protein signature 54 62 2.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 PRINTS PR00301 70kDa heat shock protein signature 334 350 2.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 PRINTS PR00301 70kDa heat shock protein signature 469 485 2.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 PRINTS PR00301 70kDa heat shock protein signature 138 158 2.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 PRINTS PR00301 70kDa heat shock protein signature 388 407 2.2E-80 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 Pfam PF00012 Hsp70 protein 4 603 2.0E-263 T 13-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 Gene3D G3DSA:3.30.420.40 5 379 9.0E-167 T 13-10-2018 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 Gene3D G3DSA:2.60.34.10 384 523 1.8E-65 T 13-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 634 37.021 T 13-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 THITH_13125 d9dd9388674320cbcace1cc0b7e1411f 639 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 13-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 THITH_16960 3e807c9c5ce4fbb49c8ddaa7f1a20512 623 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 271 285 - T 13-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 THITH_16960 3e807c9c5ce4fbb49c8ddaa7f1a20512 623 SMART SM01228 543 614 3.3E-39 T 13-10-2018 THITH_16960 3e807c9c5ce4fbb49c8ddaa7f1a20512 623 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 366 389 - T 13-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 THITH_16960 3e807c9c5ce4fbb49c8ddaa7f1a20512 623 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 3 621 41.674 T 13-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 THITH_16960 3e807c9c5ce4fbb49c8ddaa7f1a20512 623 Gene3D G3DSA:1.10.10.1800 457 547 6.7E-18 T 13-10-2018 THITH_16960 3e807c9c5ce4fbb49c8ddaa7f1a20512 623 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 5 619 2.5E-261 T 13-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 THITH_16960 3e807c9c5ce4fbb49c8ddaa7f1a20512 623 Pfam PF13932 GidA associated domain 400 612 1.1E-74 T 13-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 THITH_16960 3e807c9c5ce4fbb49c8ddaa7f1a20512 623 SUPERFAMILY SSF51905 5 258 3.46E-45 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_16960 3e807c9c5ce4fbb49c8ddaa7f1a20512 623 Gene3D G3DSA:3.50.50.60 1 220 2.8E-88 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_16960 3e807c9c5ce4fbb49c8ddaa7f1a20512 623 Gene3D G3DSA:3.50.50.60 298 456 6.1E-56 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_16960 3e807c9c5ce4fbb49c8ddaa7f1a20512 623 Pfam PF01134 Glucose inhibited division protein A 6 396 1.8E-160 T 13-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 THITH_16960 3e807c9c5ce4fbb49c8ddaa7f1a20512 623 Gene3D G3DSA:1.10.150.570 566 619 7.7E-22 T 13-10-2018 THITH_03990 357a6a24bc54b713707b7cbb85963747 358 Pfam PF00665 Integrase core domain 139 254 1.1E-20 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 THITH_03990 357a6a24bc54b713707b7cbb85963747 358 SUPERFAMILY SSF53098 139 302 2.88E-40 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_03990 357a6a24bc54b713707b7cbb85963747 358 Gene3D G3DSA:3.30.420.10 140 300 2.2E-11 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_03990 357a6a24bc54b713707b7cbb85963747 358 Pfam PF13565 Homeodomain-like domain 37 112 4.7E-9 T 13-10-2018 THITH_04840 fa3cb01aca400a47de0bc7367dfc2c97 437 Gene3D G3DSA:3.30.70.260 349 421 6.8E-170 T 13-10-2018 THITH_04840 fa3cb01aca400a47de0bc7367dfc2c97 437 Gene3D G3DSA:3.30.360.10 136 348 6.8E-170 T 13-10-2018 THITH_04840 fa3cb01aca400a47de0bc7367dfc2c97 437 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 183 205 - T 13-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 THITH_04840 fa3cb01aca400a47de0bc7367dfc2c97 437 Pfam PF01842 ACT domain 355 421 3.9E-11 T 13-10-2018 IPR002912 ACT domain THITH_04840 fa3cb01aca400a47de0bc7367dfc2c97 437 Pfam PF00742 Homoserine dehydrogenase 137 315 3.3E-65 T 13-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 THITH_04840 fa3cb01aca400a47de0bc7367dfc2c97 437 Gene3D G3DSA:3.40.50.720 4 340 6.8E-170 T 13-10-2018 THITH_04840 fa3cb01aca400a47de0bc7367dfc2c97 437 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 10 129 3.5E-18 T 13-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 THITH_04840 fa3cb01aca400a47de0bc7367dfc2c97 437 PIRSF PIRSF000098 1 434 2.0E-164 T 13-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 THITH_04840 fa3cb01aca400a47de0bc7367dfc2c97 437 SUPERFAMILY SSF51735 3 140 3.05E-36 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_04840 fa3cb01aca400a47de0bc7367dfc2c97 437 SUPERFAMILY SSF55021 354 421 5.6E-12 T 13-10-2018 THITH_04840 fa3cb01aca400a47de0bc7367dfc2c97 437 SUPERFAMILY SSF55347 137 302 1.57E-54 T 13-10-2018 THITH_14290 055629793d09f550bc10475b863ed7d0 214 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 4 207 1.6E-88 T 13-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14290 055629793d09f550bc10475b863ed7d0 214 Pfam PF00297 Ribosomal protein L3 102 185 2.8E-17 T 13-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14290 055629793d09f550bc10475b863ed7d0 214 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 2 210 38.943 T 13-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14290 055629793d09f550bc10475b863ed7d0 214 Gene3D G3DSA:2.40.30.10 132 213 7.2E-16 T 13-10-2018 THITH_14290 055629793d09f550bc10475b863ed7d0 214 ProSitePatterns PS00474 Ribosomal protein L3 signature. 104 127 - T 13-10-2018 IPR019926 Ribosomal protein L3, conserved site THITH_14290 055629793d09f550bc10475b863ed7d0 214 Gene3D G3DSA:2.40.50.620 33 96 6.2E-17 T 13-10-2018 THITH_14290 055629793d09f550bc10475b863ed7d0 214 SUPERFAMILY SSF50447 2 212 3.27E-81 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THITH_14520 07ff2997c5089ab4e92eb059bc3f25a5 289 PIRSF PIRSF005917 2 289 2.9E-95 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 THITH_14520 07ff2997c5089ab4e92eb059bc3f25a5 289 SUPERFAMILY SSF53790 12 231 3.14E-75 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 THITH_14520 07ff2997c5089ab4e92eb059bc3f25a5 289 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 14 285 4.3E-72 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 THITH_14520 07ff2997c5089ab4e92eb059bc3f25a5 289 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 13 233 35.962 T 13-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 THITH_14520 07ff2997c5089ab4e92eb059bc3f25a5 289 Gene3D G3DSA:3.40.1010.10 2 120 1.1E-42 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 THITH_14520 07ff2997c5089ab4e92eb059bc3f25a5 289 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 14 211 1.1E-28 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 THITH_14520 07ff2997c5089ab4e92eb059bc3f25a5 289 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 91 102 - T 13-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 THITH_14520 07ff2997c5089ab4e92eb059bc3f25a5 289 Gene3D G3DSA:3.30.950.10 121 238 2.4E-34 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 THITH_04395 f345492956a926f22598e24c771202ac 207 SUPERFAMILY SSF53639 9 205 3.14E-49 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily THITH_04395 f345492956a926f22598e24c771202ac 207 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 15 203 7.8E-65 T 13-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 THITH_04395 f345492956a926f22598e24c771202ac 207 Gene3D G3DSA:3.40.225.10 3 202 1.9E-54 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily THITH_04395 f345492956a926f22598e24c771202ac 207 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 207 95.252 T 13-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 THITH_04395 f345492956a926f22598e24c771202ac 207 SMART SM01007 13 200 1.7E-50 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal THITH_04395 f345492956a926f22598e24c771202ac 207 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 14 199 4.8E-45 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal THITH_03585 8bb798e104f682a474e93bd2548e5e6e 110 SUPERFAMILY SSF52821 6 108 1.7E-31 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_03585 8bb798e104f682a474e93bd2548e5e6e 110 SMART SM00450 10 105 9.1E-21 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_03585 8bb798e104f682a474e93bd2548e5e6e 110 Pfam PF00581 Rhodanese-like domain 11 101 9.6E-12 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_03585 8bb798e104f682a474e93bd2548e5e6e 110 Gene3D G3DSA:3.40.250.10 4 108 3.6E-26 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_12560 c53cf7ad9b21118911311d07dbbddb3e 168 SUPERFAMILY SSF81324 3 118 4.19E-16 T 13-10-2018 THITH_12560 c53cf7ad9b21118911311d07dbbddb3e 168 Gene3D G3DSA:1.10.287.70 1 110 3.8E-11 T 13-10-2018 THITH_15405 b2d03519fd3ed3cd9945d44bff4d6d02 1153 Pfam PF00924 Mechanosensitive ion channel 917 1116 4.7E-57 T 13-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 THITH_15405 b2d03519fd3ed3cd9945d44bff4d6d02 1153 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 989 1023 - T 13-10-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 THITH_15405 b2d03519fd3ed3cd9945d44bff4d6d02 1153 SUPERFAMILY SSF82861 874 958 4.05E-7 T 13-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 THITH_15405 b2d03519fd3ed3cd9945d44bff4d6d02 1153 Gene3D G3DSA:2.30.30.60 975 1024 6.3E-13 T 13-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily THITH_15405 b2d03519fd3ed3cd9945d44bff4d6d02 1153 Pfam PF12794 Mechanosensitive ion channel inner membrane domain 1 525 856 1.6E-80 T 13-10-2018 IPR025692 Mechanosensitive ion channel inner membrane domain 1 THITH_15405 b2d03519fd3ed3cd9945d44bff4d6d02 1153 SUPERFAMILY SSF82689 1027 1126 3.92E-28 T 13-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 THITH_15405 b2d03519fd3ed3cd9945d44bff4d6d02 1153 Gene3D G3DSA:3.30.70.100 1027 1121 8.0E-25 T 13-10-2018 THITH_15405 b2d03519fd3ed3cd9945d44bff4d6d02 1153 SUPERFAMILY SSF50182 960 1025 1.47E-17 T 13-10-2018 IPR010920 LSM domain superfamily THITH_08445 69ed2dac996d11cd4b38e04b1a8f5b11 664 SMART SM00900 16 109 9.0E-7 T 13-10-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 THITH_08445 69ed2dac996d11cd4b38e04b1a8f5b11 664 Pfam PF12801 4Fe-4S binding domain 426 469 4.7E-14 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_08445 69ed2dac996d11cd4b38e04b1a8f5b11 664 Pfam PF12801 4Fe-4S binding domain 532 574 0.0011 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_08445 69ed2dac996d11cd4b38e04b1a8f5b11 664 SUPERFAMILY SSF54862 443 611 6.19E-6 T 13-10-2018 THITH_08445 69ed2dac996d11cd4b38e04b1a8f5b11 664 PIRSF PIRSF036354 1 654 1.6E-271 T 13-10-2018 IPR011399 Nitrous oxide reductase expression regulator NosR GO:0003677|GO:0016020|GO:0045893 THITH_07600 4048c6d7d9c417dfc72a3a777b1af27a 298 SUPERFAMILY SSF53807 23 288 9.03E-65 T 13-10-2018 THITH_07600 4048c6d7d9c417dfc72a3a777b1af27a 298 Pfam PF01497 Periplasmic binding protein 44 268 1.9E-26 T 13-10-2018 IPR002491 ABC transporter periplasmic binding domain THITH_07600 4048c6d7d9c417dfc72a3a777b1af27a 298 Gene3D G3DSA:3.40.50.1980 41 159 1.4E-34 T 13-10-2018 THITH_07600 4048c6d7d9c417dfc72a3a777b1af27a 298 Gene3D G3DSA:3.40.50.1980 162 290 2.6E-29 T 13-10-2018 THITH_06840 2c8bd82c011d0eeab8761ef11291f91f 381 Gene3D G3DSA:3.40.50.11740 61 306 1.4E-108 T 13-10-2018 THITH_06840 2c8bd82c011d0eeab8761ef11291f91f 381 PIRSF PIRSF005622 1 374 5.2E-162 T 13-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 THITH_06840 2c8bd82c011d0eeab8761ef11291f91f 381 Gene3D G3DSA:1.10.10.2140 320 371 8.5E-25 T 13-10-2018 THITH_06840 2c8bd82c011d0eeab8761ef11291f91f 381 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 2 371 9.9E-149 T 13-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 THITH_06840 2c8bd82c011d0eeab8761ef11291f91f 381 Gene3D G3DSA:3.40.50.11750 19 265 1.4E-108 T 13-10-2018 THITH_06840 2c8bd82c011d0eeab8761ef11291f91f 381 Pfam PF01924 Hydrogenase formation hypA family 12 369 1.0E-158 T 13-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 THITH_03255 fc3945cf909406c3860d0f6470b19aa1 330 SUPERFAMILY SSF51735 121 292 4.31E-37 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_03255 fc3945cf909406c3860d0f6470b19aa1 330 SUPERFAMILY SSF50129 7 148 1.52E-42 T 13-10-2018 IPR011032 GroES-like superfamily THITH_03255 fc3945cf909406c3860d0f6470b19aa1 330 SMART SM00829 4 328 3.9E-7 T 13-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 THITH_03255 fc3945cf909406c3860d0f6470b19aa1 330 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 33 91 1.4E-4 T 13-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 THITH_03255 fc3945cf909406c3860d0f6470b19aa1 330 Gene3D G3DSA:3.40.50.720 130 298 4.5E-119 T 13-10-2018 THITH_03255 fc3945cf909406c3860d0f6470b19aa1 330 TIGRFAM TIGR02823 oxido_YhdH: putative quinone oxidoreductase, YhdH/YhfP family 8 328 9.3E-130 T 13-10-2018 IPR014188 Acrylyl-CoA reductase AcuI THITH_03255 fc3945cf909406c3860d0f6470b19aa1 330 Gene3D G3DSA:3.90.180.10 21 328 4.5E-119 T 13-10-2018 THITH_03255 fc3945cf909406c3860d0f6470b19aa1 330 Pfam PF00107 Zinc-binding dehydrogenase 163 272 1.7E-10 T 13-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 SUPERFAMILY SSF82714 757 838 1.7E-7 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 Gene3D G3DSA:3.30.70.1430 596 706 4.0E-229 T 13-10-2018 THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 SUPERFAMILY SSF82866 324 522 1.03E-34 T 13-10-2018 THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 SUPERFAMILY SSF82866 845 1068 8.63E-41 T 13-10-2018 THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 SUPERFAMILY SSF82693 592 707 1.99E-10 T 13-10-2018 THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 Gene3D G3DSA:3.30.70.1430 61 853 4.0E-229 T 13-10-2018 THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 Gene3D G3DSA:3.30.70.1440 707 916 4.0E-229 T 13-10-2018 THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 Gene3D G3DSA:1.20.1640.10 37 543 4.0E-229 T 13-10-2018 THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 Gene3D G3DSA:3.30.2090.10 199 290 4.0E-229 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 PRINTS PR00702 Acriflavin resistance protein family signature 363 386 9.3E-27 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 PRINTS PR00702 Acriflavin resistance protein family signature 496 519 9.3E-27 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 PRINTS PR00702 Acriflavin resistance protein family signature 59 77 9.3E-27 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 PRINTS PR00702 Acriflavin resistance protein family signature 471 494 9.3E-27 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 PRINTS PR00702 Acriflavin resistance protein family signature 417 441 9.3E-27 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 SUPERFAMILY SSF82693 61 155 2.09E-21 T 13-10-2018 THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 Gene3D G3DSA:3.30.2090.10 755 845 4.0E-229 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 SUPERFAMILY SSF82714 204 285 3.79E-16 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 Gene3D G3DSA:1.20.1640.10 544 1068 4.0E-229 T 13-10-2018 THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 Pfam PF00873 AcrB/AcrD/AcrF family 26 1068 2.0E-149 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_04860 bf3097aba8ce55232df981806ad9982e 1344 Gene3D G3DSA:3.30.70.1320 155 357 4.0E-229 T 13-10-2018 THITH_08955 123679bba8344a3ed8c6fd72d536393e 1557 Gene3D G3DSA:3.60.20.10 22 447 1.0E-184 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_08955 123679bba8344a3ed8c6fd72d536393e 1557 Gene3D G3DSA:3.20.20.70 448 801 3.7E-136 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_08955 123679bba8344a3ed8c6fd72d536393e 1557 Pfam PF01645 Conserved region in glutamate synthase 816 1186 1.3E-160 T 13-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 THITH_08955 123679bba8344a3ed8c6fd72d536393e 1557 Pfam PF01493 GXGXG motif 1267 1453 1.6E-82 T 13-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 THITH_08955 123679bba8344a3ed8c6fd72d536393e 1557 SUPERFAMILY SSF51395 453 1222 1.92E-270 T 13-10-2018 THITH_08955 123679bba8344a3ed8c6fd72d536393e 1557 Pfam PF00310 Glutamine amidotransferases class-II 22 440 7.2E-187 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain THITH_08955 123679bba8344a3ed8c6fd72d536393e 1557 SUPERFAMILY SSF56235 22 443 1.83E-158 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_08955 123679bba8344a3ed8c6fd72d536393e 1557 SUPERFAMILY SSF69336 1235 1529 3.92E-92 T 13-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 THITH_08955 123679bba8344a3ed8c6fd72d536393e 1557 Pfam PF04898 Glutamate synthase central domain 468 754 1.6E-113 T 13-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 THITH_08955 123679bba8344a3ed8c6fd72d536393e 1557 Gene3D G3DSA:2.160.20.60 1238 1538 4.3E-111 T 13-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 THITH_08955 123679bba8344a3ed8c6fd72d536393e 1557 Gene3D G3DSA:3.20.20.70 802 1237 2.7E-204 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_02305 6b4890d8ad6f9772299140567ef6c440 286 SUPERFAMILY SSF56436 33 278 1.04E-59 T 13-10-2018 IPR016187 C-type lectin fold THITH_02305 6b4890d8ad6f9772299140567ef6c440 286 Gene3D G3DSA:3.90.1580.10 24 284 2.2E-55 T 13-10-2018 THITH_02305 6b4890d8ad6f9772299140567ef6c440 286 Pfam PF03781 Sulfatase-modifying factor enzyme 1 34 277 7.9E-46 T 13-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THITH_11515 5cef1c2174941205b1bd3c79afff4394 504 SUPERFAMILY SSF53686 3 355 2.36E-110 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme THITH_11515 5cef1c2174941205b1bd3c79afff4394 504 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 42 55 - T 13-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 THITH_11515 5cef1c2174941205b1bd3c79afff4394 504 SUPERFAMILY SSF55021 327 413 1.83E-29 T 13-10-2018 THITH_11515 5cef1c2174941205b1bd3c79afff4394 504 Gene3D G3DSA:3.40.1020.10 328 504 5.4E-77 T 13-10-2018 IPR038110 Threonine dehydratase, ACT-like domain superfamily KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 THITH_11515 5cef1c2174941205b1bd3c79afff4394 504 SUPERFAMILY SSF55021 410 503 1.21E-27 T 13-10-2018 THITH_11515 5cef1c2174941205b1bd3c79afff4394 504 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 17 306 3.2E-87 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme THITH_11515 5cef1c2174941205b1bd3c79afff4394 504 Gene3D G3DSA:3.40.50.1100 50 146 2.8E-140 T 13-10-2018 THITH_11515 5cef1c2174941205b1bd3c79afff4394 504 Gene3D G3DSA:3.40.50.1100 14 317 2.8E-140 T 13-10-2018 THITH_11515 5cef1c2174941205b1bd3c79afff4394 504 TIGRFAM TIGR01124 ilvA_2Cterm: threonine ammonia-lyase, biosynthetic 5 503 1.3E-250 T 13-10-2018 IPR005787 Threonine dehydratase, biosynthetic GO:0004794|GO:0009097 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 THITH_11515 5cef1c2174941205b1bd3c79afff4394 504 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 319 409 3.1E-25 T 13-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 THITH_11515 5cef1c2174941205b1bd3c79afff4394 504 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 416 503 6.9E-24 T 13-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 THITH_04535 09b39c87dfc82dd60f97a6860d35fbf0 413 PIRSF PIRSF000355 68 413 4.6E-140 T 13-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THITH_04535 09b39c87dfc82dd60f97a6860d35fbf0 413 Pfam PF00268 Ribonucleotide reductase, small chain 93 380 1.0E-86 T 13-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THITH_04535 09b39c87dfc82dd60f97a6860d35fbf0 413 Gene3D G3DSA:1.10.620.20 72 406 7.0E-114 T 13-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 THITH_04535 09b39c87dfc82dd60f97a6860d35fbf0 413 SUPERFAMILY SSF47240 79 384 3.88E-98 T 13-10-2018 IPR009078 Ferritin-like superfamily THITH_15385 9ad86539cd48ce85661e8492ebe86635 237 Gene3D G3DSA:3.40.250.10 121 235 1.8E-16 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_15385 9ad86539cd48ce85661e8492ebe86635 237 SMART SM00450 119 225 9.6E-7 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_15385 9ad86539cd48ce85661e8492ebe86635 237 SUPERFAMILY SSF52821 112 226 2.62E-17 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_15385 9ad86539cd48ce85661e8492ebe86635 237 Gene3D G3DSA:3.10.50.40 1 120 6.1E-48 T 13-10-2018 THITH_15385 9ad86539cd48ce85661e8492ebe86635 237 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 20 110 2.9E-34 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain THITH_15385 9ad86539cd48ce85661e8492ebe86635 237 SUPERFAMILY SSF54534 6 128 3.34E-45 T 13-10-2018 THITH_15385 9ad86539cd48ce85661e8492ebe86635 237 Pfam PF00581 Rhodanese-like domain 125 221 2.5E-9 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_12850 7978ec5ead276e6bc64290178270de84 619 SMART SM00116 225 272 3.8E-7 T 13-10-2018 IPR000644 CBS domain THITH_12850 7978ec5ead276e6bc64290178270de84 619 SMART SM00116 161 208 0.038 T 13-10-2018 IPR000644 CBS domain THITH_12850 7978ec5ead276e6bc64290178270de84 619 SUPERFAMILY SSF51206 11 127 1.93E-7 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like THITH_12850 7978ec5ead276e6bc64290178270de84 619 Pfam PF03445 Putative nucleotidyltransferase DUF294 297 431 1.4E-42 T 13-10-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 THITH_12850 7978ec5ead276e6bc64290178270de84 619 SUPERFAMILY SSF54631 153 270 2.65E-28 T 13-10-2018 THITH_12850 7978ec5ead276e6bc64290178270de84 619 SUPERFAMILY SSF81301 288 395 2.58E-6 T 13-10-2018 THITH_12850 7978ec5ead276e6bc64290178270de84 619 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 471 612 1.2E-46 T 13-10-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding THITH_12850 7978ec5ead276e6bc64290178270de84 619 Gene3D G3DSA:3.10.580.10 149 276 3.2E-30 T 13-10-2018 THITH_12850 7978ec5ead276e6bc64290178270de84 619 Pfam PF00571 CBS domain 154 206 4.1E-8 T 13-10-2018 IPR000644 CBS domain THITH_12850 7978ec5ead276e6bc64290178270de84 619 Pfam PF00571 CBS domain 218 270 1.3E-8 T 13-10-2018 IPR000644 CBS domain THITH_09010 dc6b72e115dc2ae15f5c99a10bf8bbe2 422 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 326 335 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site THITH_09010 dc6b72e115dc2ae15f5c99a10bf8bbe2 422 Gene3D G3DSA:3.30.450.20 1 104 1.3E-8 T 13-10-2018 THITH_09010 dc6b72e115dc2ae15f5c99a10bf8bbe2 422 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 385 402 6.0E-6 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_09010 dc6b72e115dc2ae15f5c99a10bf8bbe2 422 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 402 422 6.0E-6 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_09010 dc6b72e115dc2ae15f5c99a10bf8bbe2 422 Gene3D G3DSA:1.10.10.60 385 422 9.8E-9 T 13-10-2018 THITH_09010 dc6b72e115dc2ae15f5c99a10bf8bbe2 422 SUPERFAMILY SSF55785 2 96 4.36E-9 T 13-10-2018 IPR035965 PAS domain superfamily THITH_09010 dc6b72e115dc2ae15f5c99a10bf8bbe2 422 Gene3D G3DSA:1.10.8.60 286 362 1.7E-22 T 13-10-2018 THITH_09010 dc6b72e115dc2ae15f5c99a10bf8bbe2 422 SUPERFAMILY SSF46689 327 421 2.01E-10 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_09010 dc6b72e115dc2ae15f5c99a10bf8bbe2 422 Pfam PF02954 Bacterial regulatory protein, Fis family 388 418 4.2E-8 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_09010 dc6b72e115dc2ae15f5c99a10bf8bbe2 422 Pfam PF08448 PAS fold 2 103 1.4E-9 T 13-10-2018 IPR013656 PAS fold-4 THITH_09010 dc6b72e115dc2ae15f5c99a10bf8bbe2 422 SMART SM00382 135 278 2.6E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_09010 dc6b72e115dc2ae15f5c99a10bf8bbe2 422 Pfam PF00158 Sigma-54 interaction domain 116 281 8.6E-62 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THITH_09010 dc6b72e115dc2ae15f5c99a10bf8bbe2 422 SUPERFAMILY SSF52540 115 356 1.05E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_09010 dc6b72e115dc2ae15f5c99a10bf8bbe2 422 Gene3D G3DSA:3.40.50.300 105 285 7.0E-61 T 13-10-2018 THITH_09330 fc22684f4c220e9f727176ea57a6e291 358 Pfam PF00665 Integrase core domain 139 254 4.9E-21 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 THITH_09330 fc22684f4c220e9f727176ea57a6e291 358 SUPERFAMILY SSF53098 139 302 4.55E-40 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_09330 fc22684f4c220e9f727176ea57a6e291 358 Gene3D G3DSA:3.30.420.10 140 300 9.0E-12 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_09330 fc22684f4c220e9f727176ea57a6e291 358 Pfam PF13565 Homeodomain-like domain 37 112 4.7E-9 T 13-10-2018 THITH_11190 fc22684f4c220e9f727176ea57a6e291 358 Pfam PF00665 Integrase core domain 139 254 4.9E-21 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 THITH_11190 fc22684f4c220e9f727176ea57a6e291 358 SUPERFAMILY SSF53098 139 302 4.55E-40 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_11190 fc22684f4c220e9f727176ea57a6e291 358 Gene3D G3DSA:3.30.420.10 140 300 9.0E-12 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_11190 fc22684f4c220e9f727176ea57a6e291 358 Pfam PF13565 Homeodomain-like domain 37 112 4.7E-9 T 13-10-2018 THITH_02960 fc22684f4c220e9f727176ea57a6e291 358 Pfam PF00665 Integrase core domain 139 254 4.9E-21 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 THITH_02960 fc22684f4c220e9f727176ea57a6e291 358 SUPERFAMILY SSF53098 139 302 4.55E-40 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_02960 fc22684f4c220e9f727176ea57a6e291 358 Gene3D G3DSA:3.30.420.10 140 300 9.0E-12 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_02960 fc22684f4c220e9f727176ea57a6e291 358 Pfam PF13565 Homeodomain-like domain 37 112 4.7E-9 T 13-10-2018 THITH_05155 fc22684f4c220e9f727176ea57a6e291 358 Pfam PF00665 Integrase core domain 139 254 4.9E-21 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 THITH_05155 fc22684f4c220e9f727176ea57a6e291 358 SUPERFAMILY SSF53098 139 302 4.55E-40 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_05155 fc22684f4c220e9f727176ea57a6e291 358 Gene3D G3DSA:3.30.420.10 140 300 9.0E-12 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_05155 fc22684f4c220e9f727176ea57a6e291 358 Pfam PF13565 Homeodomain-like domain 37 112 4.7E-9 T 13-10-2018 THITH_13760 fc22684f4c220e9f727176ea57a6e291 358 Pfam PF00665 Integrase core domain 139 254 4.9E-21 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 THITH_13760 fc22684f4c220e9f727176ea57a6e291 358 SUPERFAMILY SSF53098 139 302 4.55E-40 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_13760 fc22684f4c220e9f727176ea57a6e291 358 Gene3D G3DSA:3.30.420.10 140 300 9.0E-12 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_13760 fc22684f4c220e9f727176ea57a6e291 358 Pfam PF13565 Homeodomain-like domain 37 112 4.7E-9 T 13-10-2018 THITH_09785 fc22684f4c220e9f727176ea57a6e291 358 Pfam PF00665 Integrase core domain 139 254 4.9E-21 T 13-10-2018 IPR001584 Integrase, catalytic core GO:0015074 THITH_09785 fc22684f4c220e9f727176ea57a6e291 358 SUPERFAMILY SSF53098 139 302 4.55E-40 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_09785 fc22684f4c220e9f727176ea57a6e291 358 Gene3D G3DSA:3.30.420.10 140 300 9.0E-12 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_09785 fc22684f4c220e9f727176ea57a6e291 358 Pfam PF13565 Homeodomain-like domain 37 112 4.7E-9 T 13-10-2018 THITH_14755 e93cf9c1bd24b181672deb1de2e39299 223 SUPERFAMILY SSF53098 13 207 2.32E-51 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_14755 e93cf9c1bd24b181672deb1de2e39299 223 Hamap MF_00157 Ribonuclease T [rnt]. 1 223 86.807 T 13-10-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 THITH_14755 e93cf9c1bd24b181672deb1de2e39299 223 TIGRFAM TIGR01298 RNaseT: ribonuclease T 14 212 3.9E-83 T 13-10-2018 IPR005987 Ribonuclease T GO:0004540|GO:0006396 THITH_14755 e93cf9c1bd24b181672deb1de2e39299 223 SMART SM00479 22 207 9.8E-25 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THITH_14755 e93cf9c1bd24b181672deb1de2e39299 223 Gene3D G3DSA:3.30.420.10 13 216 1.1E-52 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_14755 e93cf9c1bd24b181672deb1de2e39299 223 Pfam PF00929 Exonuclease 24 198 5.0E-26 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THITH_05850 eae0a8257e33ee4c3bfb3cd429dcd5ff 189 SMART SM00530 77 134 5.9E-4 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_05850 eae0a8257e33ee4c3bfb3cd429dcd5ff 189 Pfam PF15731 Antitoxin component of bacterial toxin-antitoxin system, MqsA 8 134 4.1E-27 T 13-10-2018 IPR032758 Antitoxin MqsA/HigA-2 THITH_05850 eae0a8257e33ee4c3bfb3cd429dcd5ff 189 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 8 46 6.0E-7 T 13-10-2018 IPR022453 Zinc finger, MqsA-type THITH_05850 eae0a8257e33ee4c3bfb3cd429dcd5ff 189 TIGRFAM TIGR03830 CxxCG_CxxCG_HTH: putative zinc finger/helix-turn-helix protein, YgiT family 8 134 2.3E-38 T 13-10-2018 IPR022452 Antitoxin MqsA THITH_05850 eae0a8257e33ee4c3bfb3cd429dcd5ff 189 Gene3D G3DSA:1.10.260.40 19 135 5.7E-28 T 13-10-2018 THITH_05850 eae0a8257e33ee4c3bfb3cd429dcd5ff 189 SUPERFAMILY SSF47413 74 124 1.41E-6 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 THITH_04705 38611013d53c12c8b50191a514207bd5 333 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 266 308 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THITH_04705 38611013d53c12c8b50191a514207bd5 333 SUPERFAMILY SSF51182 20 87 4.89E-5 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily THITH_04705 38611013d53c12c8b50191a514207bd5 333 Pfam PF12852 Cupin 11 197 4.6E-46 T 13-10-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain THITH_04705 38611013d53c12c8b50191a514207bd5 333 SUPERFAMILY SSF46689 212 263 2.69E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_04705 38611013d53c12c8b50191a514207bd5 333 Gene3D G3DSA:2.60.120.10 43 92 2.0E-5 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_04705 38611013d53c12c8b50191a514207bd5 333 Pfam PF12833 Helix-turn-helix domain 235 313 4.3E-18 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THITH_04705 38611013d53c12c8b50191a514207bd5 333 SUPERFAMILY SSF46689 265 317 8.06E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_04705 38611013d53c12c8b50191a514207bd5 333 SMART SM00342 229 312 1.8E-25 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THITH_04705 38611013d53c12c8b50191a514207bd5 333 Gene3D G3DSA:1.10.10.60 208 326 2.6E-25 T 13-10-2018 THITH_03865 6838750dd615b0384d1d4bddb5169134 495 Gene3D G3DSA:1.10.287.130 263 335 8.2E-19 T 13-10-2018 THITH_03865 6838750dd615b0384d1d4bddb5169134 495 SUPERFAMILY SSF158472 199 241 6.93E-5 T 13-10-2018 THITH_03865 6838750dd615b0384d1d4bddb5169134 495 SUPERFAMILY SSF47384 261 334 6.47E-12 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_03865 6838750dd615b0384d1d4bddb5169134 495 Pfam PF00672 HAMP domain 203 241 2.3E-6 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_03865 6838750dd615b0384d1d4bddb5169134 495 SMART SM00387 381 491 2.1E-34 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_03865 6838750dd615b0384d1d4bddb5169134 495 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 382 489 5.3E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_03865 6838750dd615b0384d1d4bddb5169134 495 Gene3D G3DSA:3.30.565.10 338 493 9.0E-37 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_03865 6838750dd615b0384d1d4bddb5169134 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 469 3.1E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_03865 6838750dd615b0384d1d4bddb5169134 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 448 3.1E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_03865 6838750dd615b0384d1d4bddb5169134 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 475 488 3.1E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_03865 6838750dd615b0384d1d4bddb5169134 495 PRINTS PR00344 Bacterial sensor protein C-terminal signature 420 434 3.1E-17 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_03865 6838750dd615b0384d1d4bddb5169134 495 SMART SM00388 271 337 4.1E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_03865 6838750dd615b0384d1d4bddb5169134 495 SUPERFAMILY SSF55874 327 489 3.14E-37 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_03865 6838750dd615b0384d1d4bddb5169134 495 SMART SM00304 195 247 3.1E-5 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_03865 6838750dd615b0384d1d4bddb5169134 495 Pfam PF00512 His Kinase A (phospho-acceptor) domain 273 334 1.1E-9 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_09470 04fa8881d87812cc39c10591af0a8222 392 SUPERFAMILY SSF141868 140 384 1.28E-86 T 13-10-2018 IPR035919 EAL domain superfamily THITH_09470 04fa8881d87812cc39c10591af0a8222 392 Pfam PF00563 EAL domain 141 376 5.4E-70 T 13-10-2018 IPR001633 EAL domain THITH_09470 04fa8881d87812cc39c10591af0a8222 392 Pfam PF00990 Diguanylate cyclase, GGDEF domain 1 121 5.7E-35 T 13-10-2018 IPR000160 GGDEF domain THITH_09470 04fa8881d87812cc39c10591af0a8222 392 SMART SM00267 1 125 1.4E-24 T 13-10-2018 IPR000160 GGDEF domain THITH_09470 04fa8881d87812cc39c10591af0a8222 392 SUPERFAMILY SSF55073 1 127 1.33E-39 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_09470 04fa8881d87812cc39c10591af0a8222 392 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 1 123 1.3E-31 T 13-10-2018 IPR000160 GGDEF domain THITH_09470 04fa8881d87812cc39c10591af0a8222 392 SMART SM00052 135 381 1.0E-114 T 13-10-2018 IPR001633 EAL domain THITH_09470 04fa8881d87812cc39c10591af0a8222 392 Gene3D G3DSA:3.30.70.270 1 138 2.0E-47 T 13-10-2018 THITH_09470 04fa8881d87812cc39c10591af0a8222 392 Gene3D G3DSA:3.20.20.450 139 386 1.6E-101 T 13-10-2018 IPR035919 EAL domain superfamily THITH_05490 bf9196c3fd5385c13553643022b4a022 257 Gene3D G3DSA:3.40.50.720 10 232 2.9E-36 T 13-10-2018 THITH_05490 bf9196c3fd5385c13553643022b4a022 257 SUPERFAMILY SSF51735 10 231 9.71E-36 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_05490 bf9196c3fd5385c13553643022b4a022 257 Pfam PF00106 short chain dehydrogenase 11 185 5.3E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_05490 bf9196c3fd5385c13553643022b4a022 257 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 184 0.003 T 13-10-2018 THITH_05490 bf9196c3fd5385c13553643022b4a022 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 1.5E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_05490 bf9196c3fd5385c13553643022b4a022 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.5E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_05490 bf9196c3fd5385c13553643022b4a022 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.5E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_05490 bf9196c3fd5385c13553643022b4a022 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.5E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_05490 bf9196c3fd5385c13553643022b4a022 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 1.5E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 SUPERFAMILY SSF47384 494 566 1.26E-10 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 Gene3D G3DSA:1.10.287.130 488 567 2.8E-11 T 13-10-2018 THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 Pfam PF00672 HAMP domain 309 357 6.4E-12 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 Gene3D G3DSA:3.30.450.20 365 487 6.1E-6 T 13-10-2018 THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 Gene3D G3DSA:1.20.1480.50 279 364 3.7E-12 T 13-10-2018 THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 611 720 9.3E-21 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 PRINTS PR00344 Bacterial sensor protein C-terminal signature 671 681 2.3E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 PRINTS PR00344 Bacterial sensor protein C-terminal signature 682 700 2.3E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 PRINTS PR00344 Bacterial sensor protein C-terminal signature 653 667 2.3E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 PRINTS PR00344 Bacterial sensor protein C-terminal signature 706 719 2.3E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 PIRSF PIRSF037532 5 725 2.4E-211 T 13-10-2018 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 SUPERFAMILY SSF158472 309 358 7.32E-11 T 13-10-2018 THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 Gene3D G3DSA:3.30.565.10 573 724 8.1E-41 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 SUPERFAMILY SSF55785 364 476 1.91E-9 T 13-10-2018 IPR035965 PAS domain superfamily THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 Pfam PF00512 His Kinase A (phospho-acceptor) domain 499 566 1.2E-9 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 SMART SM00304 309 361 1.4E-14 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 Pfam PF13188 PAS domain 375 418 2.3E-4 T 13-10-2018 IPR000014 PAS domain THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 SUPERFAMILY SSF55874 559 722 4.58E-37 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 SMART SM00387 610 722 6.1E-33 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_15565 01d758ecdfe5243a747049b5ff307fea 734 SMART SM00388 498 570 2.4E-9 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_16190 7cbfde47c39eb92c48f22e58ff364fad 176 Gene3D G3DSA:1.10.8.640 26 109 2.0E-29 T 13-10-2018 IPR038297 CcmH/CycL/Ccl2/NrfF domain superfamily THITH_16190 7cbfde47c39eb92c48f22e58ff364fad 176 Pfam PF03918 Cytochrome C biogenesis protein 21 150 6.4E-44 T 13-10-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family THITH_06930 b7b6bc82f1b1d928e3a9b93f23dfd6a0 945 SUPERFAMILY SSF56176 7 268 1.13E-55 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 THITH_06930 b7b6bc82f1b1d928e3a9b93f23dfd6a0 945 SUPERFAMILY SSF46548 503 623 1.2E-19 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_06930 b7b6bc82f1b1d928e3a9b93f23dfd6a0 945 Pfam PF02913 FAD linked oxidases, C-terminal domain 268 515 3.1E-55 T 13-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 THITH_06930 b7b6bc82f1b1d928e3a9b93f23dfd6a0 945 Gene3D G3DSA:3.30.70.2740 394 477 2.7E-6 T 13-10-2018 THITH_06930 b7b6bc82f1b1d928e3a9b93f23dfd6a0 945 Gene3D G3DSA:3.30.465.10 98 208 1.5E-9 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 THITH_06930 b7b6bc82f1b1d928e3a9b93f23dfd6a0 945 Pfam PF01565 FAD binding domain 43 179 1.4E-26 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THITH_06930 b7b6bc82f1b1d928e3a9b93f23dfd6a0 945 Gene3D G3DSA:3.30.43.10 5 91 1.0E-12 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 THITH_06930 b7b6bc82f1b1d928e3a9b93f23dfd6a0 945 Gene3D G3DSA:3.40.462.40 268 291 1.0E-5 T 13-10-2018 THITH_06930 b7b6bc82f1b1d928e3a9b93f23dfd6a0 945 Gene3D G3DSA:3.30.465.40 243 267 1.0E-5 T 13-10-2018 THITH_06930 b7b6bc82f1b1d928e3a9b93f23dfd6a0 945 Pfam PF12838 4Fe-4S dicluster domain 541 612 4.2E-8 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_06930 b7b6bc82f1b1d928e3a9b93f23dfd6a0 945 Gene3D G3DSA:1.10.45.10 484 517 3.8E-5 T 13-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 THITH_06930 b7b6bc82f1b1d928e3a9b93f23dfd6a0 945 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 542 553 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_06930 b7b6bc82f1b1d928e3a9b93f23dfd6a0 945 SUPERFAMILY SSF55103 271 524 1.42E-55 T 13-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 THITH_06930 b7b6bc82f1b1d928e3a9b93f23dfd6a0 945 Pfam PF02754 Cysteine-rich domain 709 801 0.0012 T 13-10-2018 IPR004017 Cysteine-rich domain THITH_06930 b7b6bc82f1b1d928e3a9b93f23dfd6a0 945 Gene3D G3DSA:1.10.1060.10 519 627 8.7E-7 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_02705 3bb549d7f960387b676e166b0f4f08ce 223 SUPERFAMILY SSF46626 105 215 4.43E-14 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_02705 3bb549d7f960387b676e166b0f4f08ce 223 Pfam PF00034 Cytochrome c 138 214 2.2E-5 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_02705 3bb549d7f960387b676e166b0f4f08ce 223 Gene3D G3DSA:1.10.760.10 47 223 2.3E-58 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_02705 3bb549d7f960387b676e166b0f4f08ce 223 TIGRFAM TIGR04485 thiosulf_SoxX: sulfur oxidation c-type cytochrome SoxX 138 216 5.8E-24 T 13-10-2018 IPR030999 Sulfur oxidation c-type cytochrome SoxX THITH_09465 264d657fb0e35183c1f490943602791d 253 Gene3D G3DSA:1.10.150.720 24 109 3.5E-52 T 13-10-2018 THITH_09465 264d657fb0e35183c1f490943602791d 253 Pfam PF13419 Haloacid dehalogenase-like hydrolase 112 212 1.8E-14 T 13-10-2018 THITH_09465 264d657fb0e35183c1f490943602791d 253 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 128 208 1.7E-9 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_09465 264d657fb0e35183c1f490943602791d 253 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 157 173 1.7E-10 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_09465 264d657fb0e35183c1f490943602791d 253 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 127 140 1.7E-10 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_09465 264d657fb0e35183c1f490943602791d 253 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 8 19 1.7E-10 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_09465 264d657fb0e35183c1f490943602791d 253 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 203 216 1.7E-10 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_09465 264d657fb0e35183c1f490943602791d 253 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 116 212 1.1E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_09465 264d657fb0e35183c1f490943602791d 253 Gene3D G3DSA:3.40.50.1000 11 220 3.5E-52 T 13-10-2018 IPR023214 HAD superfamily THITH_09465 264d657fb0e35183c1f490943602791d 253 TIGRFAM TIGR02252 DREG-2: HAD hydrolase, REG-2-like, family IA 9 213 2.4E-50 T 13-10-2018 IPR011949 HAD-superfamily hydrolase, subfamily IA, REG-2-like THITH_09465 264d657fb0e35183c1f490943602791d 253 SUPERFAMILY SSF56784 8 238 1.62E-37 T 13-10-2018 IPR036412 HAD-like superfamily THITH_04530 87460a023545cb5fc4d181888e76ecd5 970 SUPERFAMILY SSF51998 377 915 2.59E-181 T 13-10-2018 THITH_04530 87460a023545cb5fc4d181888e76ecd5 970 Gene3D G3DSA:3.20.70.20 226 922 7.5E-250 T 13-10-2018 THITH_04530 87460a023545cb5fc4d181888e76ecd5 970 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 304 915 7.3E-214 T 13-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THITH_04530 87460a023545cb5fc4d181888e76ecd5 970 Pfam PF03477 ATP cone domain 37 134 3.4E-17 T 13-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 THITH_04530 87460a023545cb5fc4d181888e76ecd5 970 Pfam PF03477 ATP cone domain 155 240 1.4E-7 T 13-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 THITH_04530 87460a023545cb5fc4d181888e76ecd5 970 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 756 778 - T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THITH_04530 87460a023545cb5fc4d181888e76ecd5 970 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 301 372 4.3E-21 T 13-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THITH_04530 87460a023545cb5fc4d181888e76ecd5 970 Pfam PF02867 Ribonucleotide reductase, barrel domain 378 912 2.5E-181 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THITH_04530 87460a023545cb5fc4d181888e76ecd5 970 PRINTS PR01183 Ribonucleotide reductase large chain signature 588 599 7.2E-44 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THITH_04530 87460a023545cb5fc4d181888e76ecd5 970 PRINTS PR01183 Ribonucleotide reductase large chain signature 691 714 7.2E-44 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THITH_04530 87460a023545cb5fc4d181888e76ecd5 970 PRINTS PR01183 Ribonucleotide reductase large chain signature 663 685 7.2E-44 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THITH_04530 87460a023545cb5fc4d181888e76ecd5 970 PRINTS PR01183 Ribonucleotide reductase large chain signature 625 648 7.2E-44 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THITH_04530 87460a023545cb5fc4d181888e76ecd5 970 PRINTS PR01183 Ribonucleotide reductase large chain signature 453 472 7.2E-44 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THITH_04530 87460a023545cb5fc4d181888e76ecd5 970 PRINTS PR01183 Ribonucleotide reductase large chain signature 767 794 7.2E-44 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THITH_04530 87460a023545cb5fc4d181888e76ecd5 970 SUPERFAMILY SSF48168 160 376 4.45E-61 T 13-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THITH_16025 f8213e003c88f63136febec7de984060 430 SUPERFAMILY SSF51556 56 364 1.57E-89 T 13-10-2018 IPR032466 Metal-dependent hydrolase THITH_16025 f8213e003c88f63136febec7de984060 430 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 25 420 4.5E-96 T 13-10-2018 THITH_16025 f8213e003c88f63136febec7de984060 430 Gene3D G3DSA:2.30.40.10 9 419 5.4E-119 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 THITH_16025 f8213e003c88f63136febec7de984060 430 Pfam PF01979 Amidohydrolase family 53 419 1.8E-28 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 THITH_16025 f8213e003c88f63136febec7de984060 430 SUPERFAMILY SSF51338 1 423 9.51E-24 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 THITH_16025 f8213e003c88f63136febec7de984060 430 Gene3D G3DSA:3.20.20.140 57 368 5.4E-119 T 13-10-2018 THITH_03930 1e4e17fdb30ac318caad4cbc1301dc3e 289 SUPERFAMILY SSF51735 123 280 2.15E-49 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_03930 1e4e17fdb30ac318caad4cbc1301dc3e 289 ProSitePatterns PS00766 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 1. 76 101 - T 13-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THITH_03930 1e4e17fdb30ac318caad4cbc1301dc3e 289 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 283 37.539 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THITH_03930 1e4e17fdb30ac318caad4cbc1301dc3e 289 Gene3D G3DSA:3.40.50.720 6 259 3.2E-106 T 13-10-2018 THITH_03930 1e4e17fdb30ac318caad4cbc1301dc3e 289 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 124 279 1.3E-61 T 13-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THITH_03930 1e4e17fdb30ac318caad4cbc1301dc3e 289 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 260 268 - T 13-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THITH_03930 1e4e17fdb30ac318caad4cbc1301dc3e 289 SUPERFAMILY SSF53223 1 122 3.07E-40 T 13-10-2018 THITH_03930 1e4e17fdb30ac318caad4cbc1301dc3e 289 Gene3D G3DSA:3.40.50.10860 8 276 3.2E-106 T 13-10-2018 THITH_03930 1e4e17fdb30ac318caad4cbc1301dc3e 289 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 121 2.7E-40 T 13-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THITH_03930 1e4e17fdb30ac318caad4cbc1301dc3e 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 239 255 4.0E-80 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THITH_03930 1e4e17fdb30ac318caad4cbc1301dc3e 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 34 56 4.0E-80 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THITH_03930 1e4e17fdb30ac318caad4cbc1301dc3e 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 110 131 4.0E-80 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THITH_03930 1e4e17fdb30ac318caad4cbc1301dc3e 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 204 233 4.0E-80 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THITH_03930 1e4e17fdb30ac318caad4cbc1301dc3e 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 256 274 4.0E-80 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THITH_03930 1e4e17fdb30ac318caad4cbc1301dc3e 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 75 102 4.0E-80 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THITH_03930 1e4e17fdb30ac318caad4cbc1301dc3e 289 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 155 175 4.0E-80 T 13-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 THITH_14810 310cbda0e7eb8dd26d70b9da0c65241c 361 Pfam PF00472 RF-1 domain 215 323 9.7E-42 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THITH_14810 310cbda0e7eb8dd26d70b9da0c65241c 361 Gene3D G3DSA:3.30.160.20 212 299 1.4E-97 T 13-10-2018 THITH_14810 310cbda0e7eb8dd26d70b9da0c65241c 361 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 359 1.3E-162 T 13-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 THITH_14810 310cbda0e7eb8dd26d70b9da0c65241c 361 Pfam PF03462 PCRF domain 13 205 3.8E-68 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 THITH_14810 310cbda0e7eb8dd26d70b9da0c65241c 361 SUPERFAMILY SSF75620 12 355 8.37E-132 T 13-10-2018 THITH_14810 310cbda0e7eb8dd26d70b9da0c65241c 361 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 230 246 - T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THITH_14810 310cbda0e7eb8dd26d70b9da0c65241c 361 Gene3D G3DSA:3.30.70.1660 114 344 1.4E-97 T 13-10-2018 THITH_14810 310cbda0e7eb8dd26d70b9da0c65241c 361 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 5 359 40.858 T 13-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 THITH_14810 310cbda0e7eb8dd26d70b9da0c65241c 361 SMART SM00937 67 180 4.6E-58 T 13-10-2018 IPR005139 Peptide chain release factor GO:0006415 THITH_14705 99ff2ca599a7b08c3fc2c0d4b0d09311 127 PIRSF PIRSF000077 1 104 5.5E-28 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THITH_14705 99ff2ca599a7b08c3fc2c0d4b0d09311 127 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 5.2E-30 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THITH_14705 99ff2ca599a7b08c3fc2c0d4b0d09311 127 Pfam PF00085 Thioredoxin 3 100 9.4E-27 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 THITH_14705 99ff2ca599a7b08c3fc2c0d4b0d09311 127 Gene3D G3DSA:3.40.30.10 1 118 4.8E-31 T 13-10-2018 THITH_14705 99ff2ca599a7b08c3fc2c0d4b0d09311 127 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 THITH_14705 99ff2ca599a7b08c3fc2c0d4b0d09311 127 PRINTS PR00421 Thioredoxin family signature 68 79 1.6E-8 T 13-10-2018 THITH_14705 99ff2ca599a7b08c3fc2c0d4b0d09311 127 PRINTS PR00421 Thioredoxin family signature 29 38 1.6E-8 T 13-10-2018 THITH_14705 99ff2ca599a7b08c3fc2c0d4b0d09311 127 PRINTS PR00421 Thioredoxin family signature 21 29 1.6E-8 T 13-10-2018 THITH_14705 99ff2ca599a7b08c3fc2c0d4b0d09311 127 SUPERFAMILY SSF52833 2 103 1.34E-33 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_06760 fe5758b2a6d2412b76921737f397ef06 217 SUPERFAMILY SSF103501 7 212 1.2E-25 T 13-10-2018 IPR036197 NarG-like superfamily THITH_08615 395dba514f9816bda89fb443f43a3d5f 161 Gene3D G3DSA:2.30.110.10 2 160 7.0E-29 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 THITH_08615 395dba514f9816bda89fb443f43a3d5f 161 SUPERFAMILY SSF50475 22 151 4.8E-14 T 13-10-2018 THITH_08615 395dba514f9816bda89fb443f43a3d5f 161 PIRSF PIRSF004633 4 161 5.1E-21 T 13-10-2018 IPR014419 Heme utilization protein with pyridoxamine 5'-phosphate domain THITH_07360 08b833a92cf01d2e0309d00d132220ea 181 SUPERFAMILY SSF109604 5 169 1.22E-33 T 13-10-2018 THITH_07360 08b833a92cf01d2e0309d00d132220ea 181 Pfam PF01966 HD domain 11 134 1.0E-17 T 13-10-2018 IPR006674 HD domain THITH_07360 08b833a92cf01d2e0309d00d132220ea 181 SMART SM00471 6 143 1.7E-7 T 13-10-2018 IPR003607 HD/PDEase domain THITH_07360 08b833a92cf01d2e0309d00d132220ea 181 Gene3D G3DSA:1.10.3210.10 1 179 8.3E-57 T 13-10-2018 THITH_14735 395038b445078b40d7be9b55289f0c51 408 TIGRFAM TIGR00032 argG: argininosuccinate synthase 7 400 1.3E-144 T 13-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THITH_14735 395038b445078b40d7be9b55289f0c51 408 Gene3D G3DSA:3.40.50.620 8 178 1.3E-159 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_14735 395038b445078b40d7be9b55289f0c51 408 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 11 19 - T 13-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THITH_14735 395038b445078b40d7be9b55289f0c51 408 SUPERFAMILY SSF52402 7 211 9.48E-53 T 13-10-2018 THITH_14735 395038b445078b40d7be9b55289f0c51 408 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 119 130 - T 13-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THITH_14735 395038b445078b40d7be9b55289f0c51 408 Gene3D G3DSA:1.20.5.470 380 404 7.0E-10 T 13-10-2018 THITH_14735 395038b445078b40d7be9b55289f0c51 408 SUPERFAMILY SSF69864 179 404 6.28E-94 T 13-10-2018 THITH_14735 395038b445078b40d7be9b55289f0c51 408 Hamap MF_00005 Argininosuccinate synthase [argG]. 5 405 52.879 T 13-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THITH_14735 395038b445078b40d7be9b55289f0c51 408 Pfam PF00764 Arginosuccinate synthase 9 400 2.2E-156 T 13-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THITH_14735 395038b445078b40d7be9b55289f0c51 408 Gene3D G3DSA:3.90.1260.10 66 359 1.3E-159 T 13-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THITH_08985 923a54e7ade275910f92820051f85539 428 Gene3D G3DSA:3.90.760.10 357 428 4.3E-24 T 13-10-2018 IPR037092 Flavocytochrome c sulphide dehydrogenase, flavin-binding domain superfamily GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 THITH_08985 923a54e7ade275910f92820051f85539 428 SUPERFAMILY SSF51905 147 284 1.55E-38 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_08985 923a54e7ade275910f92820051f85539 428 SUPERFAMILY SSF55424 360 428 1.79E-19 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THITH_08985 923a54e7ade275910f92820051f85539 428 Gene3D G3DSA:3.50.50.60 149 284 6.8E-110 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_08985 923a54e7ade275910f92820051f85539 428 Pfam PF09242 Flavocytochrome c sulphide dehydrogenase, flavin-binding 359 427 2.2E-27 T 13-10-2018 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 THITH_08985 923a54e7ade275910f92820051f85539 428 Gene3D G3DSA:3.50.50.60 36 345 6.8E-110 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_08985 923a54e7ade275910f92820051f85539 428 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 35 151 3.6E-11 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THITH_08985 923a54e7ade275910f92820051f85539 428 SUPERFAMILY SSF51905 35 354 9.47E-30 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_08985 923a54e7ade275910f92820051f85539 428 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 4 28 1.7E-4 T 13-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THITH_15390 3e1e4d662d44dcba099f56e1ad3a67dd 622 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 610 1.7E-246 T 13-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 THITH_15390 3e1e4d662d44dcba099f56e1ad3a67dd 622 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 THITH_15390 3e1e4d662d44dcba099f56e1ad3a67dd 622 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 610 44.903 T 13-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 THITH_15390 3e1e4d662d44dcba099f56e1ad3a67dd 622 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 509 520 - T 13-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 THITH_15390 3e1e4d662d44dcba099f56e1ad3a67dd 622 SUPERFAMILY SSF52016 421 612 2.2E-60 T 13-10-2018 THITH_15390 3e1e4d662d44dcba099f56e1ad3a67dd 622 Gene3D G3DSA:3.50.30.80 421 572 2.2E-55 T 13-10-2018 THITH_15390 3e1e4d662d44dcba099f56e1ad3a67dd 622 Pfam PF00920 Dehydratase family 34 607 1.8E-217 T 13-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 THITH_15390 3e1e4d662d44dcba099f56e1ad3a67dd 622 SUPERFAMILY SSF143975 3 420 1.44E-131 T 13-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 THITH_03120 891d27ac085ad5edddb632154d2ad0cb 213 SUPERFAMILY SSF69255 11 80 5.36E-10 T 13-10-2018 THITH_03120 891d27ac085ad5edddb632154d2ad0cb 213 Gene3D G3DSA:2.40.50.230 1 85 1.6E-6 T 13-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily THITH_07265 6ffea932eb3474a2c4cd2ac24e4971d6 275 Gene3D G3DSA:1.10.166.10 1 70 4.9E-31 T 13-10-2018 IPR037133 Tetrahydrodipicolinate-N-succinyltransferase, N-terminal domain superfamily KEGG: 00300+2.3.1.117 THITH_07265 6ffea932eb3474a2c4cd2ac24e4971d6 275 SUPERFAMILY SSF51161 2 256 3.67E-75 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily THITH_07265 6ffea932eb3474a2c4cd2ac24e4971d6 275 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 175 209 3.0E-13 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_07265 6ffea932eb3474a2c4cd2ac24e4971d6 275 TIGRFAM TIGR00965 dapD: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 4 272 3.3E-148 T 13-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 THITH_07265 6ffea932eb3474a2c4cd2ac24e4971d6 275 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 134 162 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 THITH_07265 6ffea932eb3474a2c4cd2ac24e4971d6 275 Hamap MF_00811 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 1 272 56.566 T 13-10-2018 IPR005664 Tetrahydrodipicolinate N-succinyltransferase, transferase hexapeptide repeat family GO:0008666|GO:0009089 KEGG: 00300+2.3.1.117 THITH_07265 6ffea932eb3474a2c4cd2ac24e4971d6 275 Pfam PF14805 Tetrahydrodipicolinate N-succinyltransferase N-terminal 3 69 3.2E-25 T 13-10-2018 IPR023180 Tetrahydrodipicolinate-N-succinyltransferase, chain A, domain 1 KEGG: 00300+2.3.1.117 THITH_07265 6ffea932eb3474a2c4cd2ac24e4971d6 275 Gene3D G3DSA:2.160.10.10 87 257 4.7E-56 T 13-10-2018 THITH_00655 d017b6cd11150c60c5e867e6e67b507f 201 ProSitePatterns PS00622 LuxR-type HTH domain signature. 154 181 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_00655 d017b6cd11150c60c5e867e6e67b507f 201 SMART SM00421 137 194 2.4E-23 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_00655 d017b6cd11150c60c5e867e6e67b507f 201 Gene3D G3DSA:1.10.10.10 84 200 9.0E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_00655 d017b6cd11150c60c5e867e6e67b507f 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 1.1E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_00655 d017b6cd11150c60c5e867e6e67b507f 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 1.1E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_00655 d017b6cd11150c60c5e867e6e67b507f 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 1.1E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_00655 d017b6cd11150c60c5e867e6e67b507f 201 SUPERFAMILY SSF46894 125 196 1.33E-20 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THITH_00655 d017b6cd11150c60c5e867e6e67b507f 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 193 5.8E-19 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 Pfam PF11808 Domain of unknown function (DUF3329) 12 90 1.1E-23 T 13-10-2018 IPR021766 Phosphate regulon sensor protein PhoR GO:0000155|GO:0000160|GO:0004721 THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 Gene3D G3DSA:3.30.450.20 86 201 1.3E-7 T 13-10-2018 THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 TIGRFAM TIGR02966 phoR_proteo: phosphate regulon sensor kinase PhoR 96 425 1.3E-123 T 13-10-2018 IPR014310 Signal transduction histidine kinase, phosphate regulon sensor PhoR GO:0000155|GO:0000160|GO:0004673|GO:0016021 THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 SUPERFAMILY SSF55785 90 198 3.49E-9 T 13-10-2018 IPR035965 PAS domain superfamily THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 426 5.3E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 382 5.3E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 354 368 5.3E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 407 5.3E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 Gene3D G3DSA:1.10.287.130 202 274 2.4E-21 T 13-10-2018 THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 SUPERFAMILY SSF47384 192 272 5.1E-19 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 SUPERFAMILY SSF55874 261 427 1.03E-41 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 317 427 1.5E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 SMART SM00091 98 164 0.0013 T 13-10-2018 IPR000014 PAS domain THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 Pfam PF00512 His Kinase A (phospho-acceptor) domain 206 272 4.2E-21 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 SMART SM00387 317 429 2.9E-34 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 Gene3D G3DSA:3.30.565.10 290 435 7.4E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 SMART SM00388 206 272 1.4E-21 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_11830 f9e68b0247e281a7c79e636d36aa78b9 444 Pfam PF13188 PAS domain 100 141 7.3E-5 T 13-10-2018 IPR000014 PAS domain THITH_13980 05c7329c39470e32f619e28de13a19c9 335 Gene3D G3DSA:3.10.290.10 19 85 5.8E-16 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 THITH_13980 05c7329c39470e32f619e28de13a19c9 335 SUPERFAMILY SSF55174 29 118 1.67E-9 T 13-10-2018 THITH_13980 05c7329c39470e32f619e28de13a19c9 335 SUPERFAMILY SSF55120 91 325 2.47E-79 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_13980 05c7329c39470e32f619e28de13a19c9 335 Pfam PF01479 S4 domain 32 77 6.7E-5 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_13980 05c7329c39470e32f619e28de13a19c9 335 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 148 162 - T 13-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_13980 05c7329c39470e32f619e28de13a19c9 335 Pfam PF00849 RNA pseudouridylate synthase 106 255 6.5E-33 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_13980 05c7329c39470e32f619e28de13a19c9 335 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 29 325 1.9E-94 T 13-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_13980 05c7329c39470e32f619e28de13a19c9 335 Gene3D G3DSA:3.30.2350.10 97 328 2.4E-76 T 13-10-2018 THITH_03010 5b9c8acac7e56c6fd3064b62c51beb10 180 Gene3D G3DSA:3.30.70.20 64 117 9.0E-61 T 13-10-2018 THITH_03010 5b9c8acac7e56c6fd3064b62c51beb10 180 SUPERFAMILY SSF54862 1 179 1.99E-62 T 13-10-2018 THITH_03010 5b9c8acac7e56c6fd3064b62c51beb10 180 Pfam PF13247 4Fe-4S dicluster domain 51 145 1.9E-24 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_03010 5b9c8acac7e56c6fd3064b62c51beb10 180 Pfam PF12837 4Fe-4S binding domain 6 25 1.8E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_03010 5b9c8acac7e56c6fd3064b62c51beb10 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 91 102 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_03010 5b9c8acac7e56c6fd3064b62c51beb10 180 Gene3D G3DSA:3.30.70.20 4 179 9.0E-61 T 13-10-2018 THITH_11920 d4182654385263d10837d623eaae7cdd 377 Gene3D G3DSA:1.10.150.530 8 68 5.0E-20 T 13-10-2018 THITH_11920 d4182654385263d10837d623eaae7cdd 377 SUPERFAMILY SSF102114 105 321 7.32E-17 T 13-10-2018 THITH_11920 d4182654385263d10837d623eaae7cdd 377 SMART SM00729 107 325 0.0068 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THITH_11920 d4182654385263d10837d623eaae7cdd 377 PIRSF PIRSF006004 5 367 2.6E-146 T 13-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 THITH_11920 d4182654385263d10837d623eaae7cdd 377 Pfam PF04055 Radical SAM superfamily 112 285 6.4E-19 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THITH_11920 d4182654385263d10837d623eaae7cdd 377 Gene3D G3DSA:3.20.20.70 70 339 1.4E-110 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_11920 d4182654385263d10837d623eaae7cdd 377 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 6 356 3.4E-140 T 13-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 THITH_11920 d4182654385263d10837d623eaae7cdd 377 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 8 354 73.407 T 13-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 THITH_13180 778a760308d69e878a7953e0e0be3fe9 236 Gene3D G3DSA:3.30.420.10 1 179 1.4E-58 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_13180 778a760308d69e878a7953e0e0be3fe9 236 SMART SM00479 2 175 5.9E-49 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THITH_13180 778a760308d69e878a7953e0e0be3fe9 236 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 4 214 4.3E-64 T 13-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_13180 778a760308d69e878a7953e0e0be3fe9 236 TIGRFAM TIGR01406 dnaQ_proteo: DNA polymerase III, epsilon subunit 2 225 4.0E-91 T 13-10-2018 IPR006309 DNA polymerase 3, epsilon subunit GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_13180 778a760308d69e878a7953e0e0be3fe9 236 SUPERFAMILY SSF53098 1 177 1.71E-56 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_13180 778a760308d69e878a7953e0e0be3fe9 236 Pfam PF00929 Exonuclease 4 166 2.1E-39 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THITH_13865 fc316542b85f68eb4b4eb1640050a502 546 Pfam PF13193 AMP-binding enzyme C-terminal domain 190 263 6.6E-11 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain THITH_13865 fc316542b85f68eb4b4eb1640050a502 546 SUPERFAMILY SSF56801 2 275 1.01E-73 T 13-10-2018 THITH_13865 fc316542b85f68eb4b4eb1640050a502 546 Gene3D G3DSA:3.40.50.12780 1 174 4.8E-49 T 13-10-2018 THITH_13865 fc316542b85f68eb4b4eb1640050a502 546 SUPERFAMILY SSF53927 374 541 4.43E-40 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 THITH_13865 fc316542b85f68eb4b4eb1640050a502 546 Gene3D G3DSA:3.30.300.30 175 281 1.7E-25 T 13-10-2018 THITH_13865 fc316542b85f68eb4b4eb1640050a502 546 Pfam PF00550 Phosphopantetheine attachment site 301 364 1.6E-16 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain THITH_13865 fc316542b85f68eb4b4eb1640050a502 546 Gene3D G3DSA:3.40.140.10 393 544 1.7E-39 T 13-10-2018 THITH_13865 fc316542b85f68eb4b4eb1640050a502 546 SMART SM00823 Phosphopantetheine attachment site 299 368 6.9E-5 T 13-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 THITH_13865 fc316542b85f68eb4b4eb1640050a502 546 Gene3D G3DSA:1.10.1200.10 298 372 3.7E-19 T 13-10-2018 IPR036736 ACP-like superfamily THITH_13865 fc316542b85f68eb4b4eb1640050a502 546 Pfam PF00501 AMP-binding enzyme 2 181 4.5E-38 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 THITH_13865 fc316542b85f68eb4b4eb1640050a502 546 SUPERFAMILY SSF47336 297 382 2.36E-17 T 13-10-2018 IPR036736 ACP-like superfamily THITH_13865 fc316542b85f68eb4b4eb1640050a502 546 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 396 491 1.7E-21 T 13-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain THITH_14170 2441f574d72037c1cfed838193a59b53 206 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 206 36.433 T 13-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 THITH_14170 2441f574d72037c1cfed838193a59b53 206 ProSitePatterns PS00632 Ribosomal protein S4 signature. 94 118 - T 13-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14170 2441f574d72037c1cfed838193a59b53 206 SMART SM00363 96 156 6.9E-17 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14170 2441f574d72037c1cfed838193a59b53 206 Gene3D G3DSA:3.10.290.10 103 191 1.4E-34 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 THITH_14170 2441f574d72037c1cfed838193a59b53 206 Pfam PF01479 S4 domain 97 143 8.8E-19 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14170 2441f574d72037c1cfed838193a59b53 206 SUPERFAMILY SSF55174 3 206 3.79E-72 T 13-10-2018 THITH_14170 2441f574d72037c1cfed838193a59b53 206 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 206 7.6E-83 T 13-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 THITH_14170 2441f574d72037c1cfed838193a59b53 206 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 95 6.2E-32 T 13-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 THITH_14170 2441f574d72037c1cfed838193a59b53 206 Gene3D G3DSA:1.10.1050.10 1 102 5.7E-44 T 13-10-2018 THITH_14170 2441f574d72037c1cfed838193a59b53 206 SMART SM01390 3 95 6.8E-47 T 13-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 THITH_14825 a1532cc56757fa2f5a1b4ef154f58df3 267 SUPERFAMILY SSF69572 6 249 3.79E-79 T 13-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 THITH_14825 a1532cc56757fa2f5a1b4ef154f58df3 267 Pfam PF00899 ThiF family 9 242 7.7E-62 T 13-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 THITH_14825 a1532cc56757fa2f5a1b4ef154f58df3 267 Gene3D G3DSA:3.40.50.720 1 250 9.6E-90 T 13-10-2018 THITH_01790 16054b6c642245f1eedd6a80e598b127 180 SUPERFAMILY SSF52141 19 171 1.57E-35 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THITH_01790 16054b6c642245f1eedd6a80e598b127 180 SMART SM00986 20 170 4.3E-11 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THITH_01790 16054b6c642245f1eedd6a80e598b127 180 Gene3D G3DSA:3.40.470.10 15 175 7.8E-56 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THITH_01790 16054b6c642245f1eedd6a80e598b127 180 TIGRFAM TIGR04274 hypoxanDNAglyco: DNA-deoxyinosine glycosylase 18 166 3.5E-50 T 13-10-2018 IPR026353 Hypoxanthine-DNA glycosylase THITH_01790 16054b6c642245f1eedd6a80e598b127 180 SMART SM00987 20 170 4.3E-11 T 13-10-2018 THITH_01790 16054b6c642245f1eedd6a80e598b127 180 Pfam PF03167 Uracil DNA glycosylase superfamily 23 166 1.3E-7 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THITH_14530 c9a4cae17fc27d69c457608838b17a33 118 Hamap MF_00048 UPF0102 protein YraN [yraN]. 4 113 21.394 T 13-10-2018 IPR003509 Uncharacterised protein family UPF0102 THITH_14530 c9a4cae17fc27d69c457608838b17a33 118 Pfam PF02021 Uncharacterised protein family UPF0102 11 98 5.6E-27 T 13-10-2018 IPR003509 Uncharacterised protein family UPF0102 THITH_14530 c9a4cae17fc27d69c457608838b17a33 118 SUPERFAMILY SSF52980 6 112 4.08E-22 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_14530 c9a4cae17fc27d69c457608838b17a33 118 TIGRFAM TIGR00252 TIGR00252: TIGR00252 family protein 7 116 1.4E-27 T 13-10-2018 IPR003509 Uncharacterised protein family UPF0102 THITH_14530 c9a4cae17fc27d69c457608838b17a33 118 Gene3D G3DSA:3.40.1350.10 10 117 5.8E-33 T 13-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 THITH_09635 c01399c4bd0ecc031daf7fe75562b90a 269 Gene3D G3DSA:3.40.50.300 1 259 2.4E-71 T 13-10-2018 THITH_09635 c01399c4bd0ecc031daf7fe75562b90a 269 PIRSF PIRSF003092 1 269 6.8E-90 T 13-10-2018 IPR025501 ATP binding protein MinD THITH_09635 c01399c4bd0ecc031daf7fe75562b90a 269 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 226 2.8E-20 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THITH_09635 c01399c4bd0ecc031daf7fe75562b90a 269 SUPERFAMILY SSF52540 1 267 6.0E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_09635 c01399c4bd0ecc031daf7fe75562b90a 269 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 2 266 2.7E-110 T 13-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 THITH_14190 7fce4f6fbf75dbf5815a2a2f3e64ab1f 447 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 19 429 1.8E-127 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THITH_14190 7fce4f6fbf75dbf5815a2a2f3e64ab1f 447 Pfam PF00344 SecY translocase 75 417 1.5E-113 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THITH_14190 7fce4f6fbf75dbf5815a2a2f3e64ab1f 447 SUPERFAMILY SSF103491 14 424 2.35E-129 T 13-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THITH_14190 7fce4f6fbf75dbf5815a2a2f3e64ab1f 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 22 40 8.8E-94 T 13-10-2018 THITH_14190 7fce4f6fbf75dbf5815a2a2f3e64ab1f 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 180 203 8.8E-94 T 13-10-2018 THITH_14190 7fce4f6fbf75dbf5815a2a2f3e64ab1f 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 402 420 8.8E-94 T 13-10-2018 THITH_14190 7fce4f6fbf75dbf5815a2a2f3e64ab1f 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 315 337 8.8E-94 T 13-10-2018 THITH_14190 7fce4f6fbf75dbf5815a2a2f3e64ab1f 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 74 94 8.8E-94 T 13-10-2018 THITH_14190 7fce4f6fbf75dbf5815a2a2f3e64ab1f 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 370 388 8.8E-94 T 13-10-2018 THITH_14190 7fce4f6fbf75dbf5815a2a2f3e64ab1f 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 115 138 8.8E-94 T 13-10-2018 THITH_14190 7fce4f6fbf75dbf5815a2a2f3e64ab1f 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 154 179 8.8E-94 T 13-10-2018 THITH_14190 7fce4f6fbf75dbf5815a2a2f3e64ab1f 447 PRINTS PR00303 Preprotein translocase SecY subunit signature 272 291 8.8E-94 T 13-10-2018 THITH_14190 7fce4f6fbf75dbf5815a2a2f3e64ab1f 447 PIRSF PIRSF004557 10 440 3.4E-124 T 13-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THITH_14190 7fce4f6fbf75dbf5815a2a2f3e64ab1f 447 Gene3D G3DSA:1.10.3370.10 11 429 5.6E-157 T 13-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THITH_14190 7fce4f6fbf75dbf5815a2a2f3e64ab1f 447 ProSitePatterns PS00756 Protein secY signature 2. 173 190 - T 13-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 THITH_14190 7fce4f6fbf75dbf5815a2a2f3e64ab1f 447 Hamap MF_01465 Protein translocase subunit SecY [secY]. 9 433 29.201 T 13-10-2018 IPR026593 Protein translocase subunit SecY THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 Gene3D G3DSA:3.30.1330.10 216 422 4.8E-39 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 SUPERFAMILY SSF55326 223 429 3.28E-58 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 TIGRFAM TIGR01735 FGAM_synt: phosphoribosylformylglycinamidine synthase 4 1294 0.0 T 13-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 SUPERFAMILY SSF56042 434 616 1.3E-47 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 Gene3D G3DSA:3.90.650.10 423 608 1.1E-56 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 Gene3D G3DSA:3.90.650.10 811 982 8.7E-27 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 Gene3D G3DSA:3.40.50.880 983 1295 6.2E-133 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 Gene3D G3DSA:3.30.1330.10 624 810 4.9E-19 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 1039 1294 6.4E-106 T 13-10-2018 THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 SUPERFAMILY SSF56042 824 1011 1.47E-42 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 SUPERFAMILY SSF55326 623 818 5.76E-61 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 SUPERFAMILY SSF52317 1036 1294 1.21E-97 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 Gene3D G3DSA:1.10.8.750 155 215 7.9E-23 T 13-10-2018 THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 SMART SM01211 1039 1294 2.2E-152 T 13-10-2018 THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 SUPERFAMILY SSF82697 1 154 8.37E-32 T 13-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 SUPERFAMILY SSF109736 158 222 2.48E-18 T 13-10-2018 THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 Hamap MF_00419 Phosphoribosylformylglycinamidine synthase [purL]. 1 1295 20.266 T 13-10-2018 IPR010073 Phosphoribosylformylglycinamidine synthase GO:0004642|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 Pfam PF02769 AIR synthase related protein, C-terminal domain 438 591 3.1E-29 T 13-10-2018 IPR010918 PurM-like, C-terminal domain THITH_07835 351806c53ce43bd7b1b7f593f4c2b31f 1295 Pfam PF02769 AIR synthase related protein, C-terminal domain 839 967 1.5E-11 T 13-10-2018 IPR010918 PurM-like, C-terminal domain THITH_05810 dbf7113350795c9c8a94854f2364a0c3 433 Pfam PF13692 Glycosyl transferases group 1 233 378 1.1E-14 T 13-10-2018 THITH_05810 dbf7113350795c9c8a94854f2364a0c3 433 Pfam PF13579 Glycosyl transferase 4-like domain 30 212 3.9E-20 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 THITH_05810 dbf7113350795c9c8a94854f2364a0c3 433 SUPERFAMILY SSF53756 31 419 8.22E-48 T 13-10-2018 THITH_05810 dbf7113350795c9c8a94854f2364a0c3 433 Gene3D G3DSA:3.40.50.2000 230 404 1.2E-22 T 13-10-2018 THITH_05810 dbf7113350795c9c8a94854f2364a0c3 433 Gene3D G3DSA:3.40.50.2000 19 223 7.6E-23 T 13-10-2018 THITH_10070 9ff169e25153c011fb2ddb52b9a596e4 739 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 137 220 5.8E-24 T 13-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 THITH_10070 9ff169e25153c011fb2ddb52b9a596e4 739 SMART SM00642 265 611 1.5E-7 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THITH_10070 9ff169e25153c011fb2ddb52b9a596e4 739 SUPERFAMILY SSF51445 192 631 6.72E-120 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily THITH_10070 9ff169e25153c011fb2ddb52b9a596e4 739 PIRSF PIRSF000463 14 739 2.8E-282 T 13-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 THITH_10070 9ff169e25153c011fb2ddb52b9a596e4 739 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 121 736 2.0E-273 T 13-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 THITH_10070 9ff169e25153c011fb2ddb52b9a596e4 739 Gene3D G3DSA:3.20.20.80 250 627 3.0E-170 T 13-10-2018 THITH_10070 9ff169e25153c011fb2ddb52b9a596e4 739 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 643 737 4.7E-15 T 13-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 THITH_10070 9ff169e25153c011fb2ddb52b9a596e4 739 SUPERFAMILY SSF81296 150 206 7.7E-12 T 13-10-2018 IPR014756 Immunoglobulin E-set THITH_10070 9ff169e25153c011fb2ddb52b9a596e4 739 Pfam PF00128 Alpha amylase, catalytic domain 290 362 2.4E-9 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THITH_10070 9ff169e25153c011fb2ddb52b9a596e4 739 SUPERFAMILY SSF51011 639 738 7.36E-26 T 13-10-2018 THITH_10070 9ff169e25153c011fb2ddb52b9a596e4 739 Gene3D G3DSA:2.60.40.10 9 234 2.9E-61 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_10070 9ff169e25153c011fb2ddb52b9a596e4 739 Gene3D G3DSA:2.60.40.1180 638 739 7.2E-28 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta THITH_10070 9ff169e25153c011fb2ddb52b9a596e4 739 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 113 739 44.477 T 13-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 THITH_10070 9ff169e25153c011fb2ddb52b9a596e4 739 SUPERFAMILY SSF81296 22 126 7.0E-9 T 13-10-2018 IPR014756 Immunoglobulin E-set THITH_08640 e26a9e20bd512703d7002b8d4b293f1b 249 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 6 247 2.9E-86 T 13-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 THITH_08640 e26a9e20bd512703d7002b8d4b293f1b 249 SUPERFAMILY SSF53167 6 249 2.23E-79 T 13-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 THITH_08640 e26a9e20bd512703d7002b8d4b293f1b 249 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 4 249 34.506 T 13-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 THITH_08640 e26a9e20bd512703d7002b8d4b293f1b 249 Gene3D G3DSA:3.40.50.1580 2 249 3.1E-80 T 13-10-2018 THITH_08640 e26a9e20bd512703d7002b8d4b293f1b 249 Pfam PF01048 Phosphorylase superfamily 6 246 3.0E-43 T 13-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 THITH_07255 0d24b4ffe76f70f20faafb3b5a3dddc3 148 Pfam PF02566 OsmC-like protein 38 131 3.4E-11 T 13-10-2018 IPR003718 OsmC/Ohr family THITH_07255 0d24b4ffe76f70f20faafb3b5a3dddc3 148 SUPERFAMILY SSF82784 37 133 2.22E-16 T 13-10-2018 IPR036102 OsmC/Ohr superfamily THITH_07255 0d24b4ffe76f70f20faafb3b5a3dddc3 148 Gene3D G3DSA:3.30.300.20 15 134 5.4E-11 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta THITH_08940 effcbe5e6edfb6db8b170d75954fdb3f 226 SUPERFAMILY SSF52172 2 174 2.72E-40 T 13-10-2018 IPR011006 CheY-like superfamily THITH_08940 effcbe5e6edfb6db8b170d75954fdb3f 226 TIGRFAM TIGR01387 cztR_silR_copR: heavy metal response regulator 3 220 1.6E-108 T 13-10-2018 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response GO:0003677|GO:0006355 THITH_08940 effcbe5e6edfb6db8b170d75954fdb3f 226 Gene3D G3DSA:1.10.10.10 123 225 4.4E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_08940 effcbe5e6edfb6db8b170d75954fdb3f 226 Gene3D G3DSA:3.40.50.2300 1 121 1.9E-39 T 13-10-2018 THITH_08940 effcbe5e6edfb6db8b170d75954fdb3f 226 SMART SM00862 145 220 7.3E-26 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THITH_08940 effcbe5e6edfb6db8b170d75954fdb3f 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 220 2.3E-25 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THITH_08940 effcbe5e6edfb6db8b170d75954fdb3f 226 Pfam PF00072 Response regulator receiver domain 3 113 6.4E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_08940 effcbe5e6edfb6db8b170d75954fdb3f 226 SMART SM00448 1 112 6.4E-41 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_16340 82b975c8064ae389bcc5640eab58dc6d 428 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 331 422 4.3E-31 T 13-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THITH_16340 82b975c8064ae389bcc5640eab58dc6d 428 SUPERFAMILY SSF51246 329 424 4.34E-33 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 THITH_16340 82b975c8064ae389bcc5640eab58dc6d 428 SUPERFAMILY SSF52440 1 103 1.41E-35 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily THITH_16340 82b975c8064ae389bcc5640eab58dc6d 428 Gene3D G3DSA:3.30.1490.20 121 190 1.6E-27 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 THITH_16340 82b975c8064ae389bcc5640eab58dc6d 428 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 103 296 2.0E-78 T 13-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THITH_16340 82b975c8064ae389bcc5640eab58dc6d 428 SUPERFAMILY SSF56059 104 326 1.59E-64 T 13-10-2018 THITH_16340 82b975c8064ae389bcc5640eab58dc6d 428 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 290 297 - T 13-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THITH_16340 82b975c8064ae389bcc5640eab58dc6d 428 SMART SM01209 103 296 1.9E-137 T 13-10-2018 THITH_16340 82b975c8064ae389bcc5640eab58dc6d 428 SMART SM01210 330 424 9.3E-52 T 13-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THITH_16340 82b975c8064ae389bcc5640eab58dc6d 428 Gene3D G3DSA:3.90.600.10 330 428 2.1E-35 T 13-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THITH_16340 82b975c8064ae389bcc5640eab58dc6d 428 Gene3D G3DSA:3.30.470.20 191 329 1.0E-56 T 13-10-2018 THITH_16340 82b975c8064ae389bcc5640eab58dc6d 428 Gene3D G3DSA:3.40.50.20 2 95 2.0E-37 T 13-10-2018 THITH_16340 82b975c8064ae389bcc5640eab58dc6d 428 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 425 7.4E-174 T 13-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THITH_16340 82b975c8064ae389bcc5640eab58dc6d 428 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 102 1.7E-35 T 13-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THITH_16340 82b975c8064ae389bcc5640eab58dc6d 428 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 424 43.535 T 13-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 THITH_05410 97cd69184f761c1dd6e25684d4f4d6e3 928 Gene3D G3DSA:1.10.10.1100 866 920 5.5E-11 T 13-10-2018 THITH_05410 97cd69184f761c1dd6e25684d4f4d6e3 928 SUPERFAMILY SSF50692 612 754 2.94E-41 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily THITH_05410 97cd69184f761c1dd6e25684d4f4d6e3 928 SUPERFAMILY SSF53706 9 603 7.46E-178 T 13-10-2018 THITH_05410 97cd69184f761c1dd6e25684d4f4d6e3 928 Gene3D G3DSA:3.40.228.10 152 602 1.0E-182 T 13-10-2018 THITH_05410 97cd69184f761c1dd6e25684d4f4d6e3 928 Pfam PF04324 BFD-like [2Fe-2S] binding domain 866 915 2.4E-14 T 13-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain THITH_05410 97cd69184f761c1dd6e25684d4f4d6e3 928 Gene3D G3DSA:3.40.50.740 86 598 1.0E-182 T 13-10-2018 THITH_05410 97cd69184f761c1dd6e25684d4f4d6e3 928 Gene3D G3DSA:2.20.25.90 9 71 1.1E-12 T 13-10-2018 THITH_05410 97cd69184f761c1dd6e25684d4f4d6e3 928 Gene3D G3DSA:2.40.40.20 612 739 2.4E-35 T 13-10-2018 THITH_05410 97cd69184f761c1dd6e25684d4f4d6e3 928 Pfam PF00384 Molybdopterin oxidoreductase 85 499 3.2E-77 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_05410 97cd69184f761c1dd6e25684d4f4d6e3 928 SMART SM00926 7 72 6.6E-13 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_05410 97cd69184f761c1dd6e25684d4f4d6e3 928 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 10 70 7.3E-15 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_05410 97cd69184f761c1dd6e25684d4f4d6e3 928 Pfam PF01568 Molydopterin dinucleotide binding domain 618 729 2.8E-30 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 THITH_04670 4761d4ad4548a8191274ac3cc24c2141 132 Pfam PF01850 PIN domain 6 113 3.4E-13 T 13-10-2018 IPR002716 PIN domain THITH_04670 4761d4ad4548a8191274ac3cc24c2141 132 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 124 11.759 T 13-10-2018 IPR022907 VapC family GO:0004540 THITH_04670 4761d4ad4548a8191274ac3cc24c2141 132 SUPERFAMILY SSF88723 4 122 2.52E-27 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_04670 4761d4ad4548a8191274ac3cc24c2141 132 Gene3D G3DSA:3.40.50.1010 1 128 7.4E-26 T 13-10-2018 THITH_04085 c5b8df44ec23f2a21d6c1d871987f487 408 Pfam PF02353 Mycolic acid cyclopropane synthetase 135 402 5.9E-83 T 13-10-2018 THITH_04085 c5b8df44ec23f2a21d6c1d871987f487 408 Gene3D G3DSA:3.40.50.150 141 408 9.1E-97 T 13-10-2018 THITH_04085 c5b8df44ec23f2a21d6c1d871987f487 408 PIRSF PIRSF003085 24 408 1.8E-124 T 13-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 THITH_04085 c5b8df44ec23f2a21d6c1d871987f487 408 SUPERFAMILY SSF53335 144 408 7.15E-80 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_16250 88d82f0a466f1a3b7692234ab0fdef54 268 Pfam PF00459 Inositol monophosphatase family 8 258 6.4E-47 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_16250 88d82f0a466f1a3b7692234ab0fdef54 268 Gene3D G3DSA:3.40.190.80 152 267 1.5E-20 T 13-10-2018 THITH_16250 88d82f0a466f1a3b7692234ab0fdef54 268 Gene3D G3DSA:3.30.540.10 6 146 1.1E-34 T 13-10-2018 THITH_16250 88d82f0a466f1a3b7692234ab0fdef54 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 180 201 2.2E-21 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_16250 88d82f0a466f1a3b7692234ab0fdef54 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 2.2E-21 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_16250 88d82f0a466f1a3b7692234ab0fdef54 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 87 103 2.2E-21 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_16250 88d82f0a466f1a3b7692234ab0fdef54 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 62 78 2.2E-21 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_16250 88d82f0a466f1a3b7692234ab0fdef54 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 2.2E-21 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_16250 88d82f0a466f1a3b7692234ab0fdef54 268 SUPERFAMILY SSF56655 8 266 1.31E-61 T 13-10-2018 THITH_16250 88d82f0a466f1a3b7692234ab0fdef54 268 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 214 228 - T 13-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 THITH_16250 88d82f0a466f1a3b7692234ab0fdef54 268 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 87 99 - T 13-10-2018 IPR020583 Inositol monophosphatase, metal-binding site THITH_02630 f1af67de13eecb6fe2038fa56e981eaa 96 Pfam PF02609 Exonuclease VII small subunit 13 63 4.5E-21 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 THITH_02630 f1af67de13eecb6fe2038fa56e981eaa 96 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 12 64 1.2E-22 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 THITH_02630 f1af67de13eecb6fe2038fa56e981eaa 96 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 12 72 15.307 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 THITH_02630 f1af67de13eecb6fe2038fa56e981eaa 96 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 8 52 1.0E-9 T 13-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 THITH_02630 f1af67de13eecb6fe2038fa56e981eaa 96 Gene3D G3DSA:1.10.287.1040 7 80 1.8E-24 T 13-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 THITH_02630 f1af67de13eecb6fe2038fa56e981eaa 96 SUPERFAMILY SSF116842 8 67 4.84E-19 T 13-10-2018 THITH_06645 47f5c7fcaf35b282b94e541f5bbd2612 301 Gene3D G3DSA:3.60.20.30 170 301 1.1E-39 T 13-10-2018 THITH_06645 47f5c7fcaf35b282b94e541f5bbd2612 301 Pfam PF01112 Asparaginase 1 295 1.7E-93 T 13-10-2018 IPR000246 Peptidase T2, asparaginase 2 GO:0016787 THITH_06645 47f5c7fcaf35b282b94e541f5bbd2612 301 SUPERFAMILY SSF56235 1 295 5.66E-83 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_17190 d28568fb155a840c60af9757af7b83a8 634 SUPERFAMILY SSF55874 506 628 3.8E-15 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_17190 d28568fb155a840c60af9757af7b83a8 634 Gene3D G3DSA:3.30.565.10 493 629 2.9E-28 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_17190 d28568fb155a840c60af9757af7b83a8 634 Pfam PF03924 CHASE domain 89 217 1.1E-12 T 13-10-2018 IPR006189 CHASE domain THITH_17190 d28568fb155a840c60af9757af7b83a8 634 SMART SM00387 526 630 3.0E-8 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_17190 d28568fb155a840c60af9757af7b83a8 634 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 530 594 3.8E-7 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_17190 d28568fb155a840c60af9757af7b83a8 634 SMART SM01079 83 277 1.5E-11 T 13-10-2018 IPR006189 CHASE domain THITH_17190 d28568fb155a840c60af9757af7b83a8 634 Pfam PF07730 Histidine kinase 420 487 2.0E-11 T 13-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 THITH_10790 22e0edb377f1dcf782b2e94c5d50dd14 360 Gene3D G3DSA:3.40.718.10 1 355 1.4E-144 T 13-10-2018 THITH_10790 22e0edb377f1dcf782b2e94c5d50dd14 360 SUPERFAMILY SSF53659 3 356 8.1E-120 T 13-10-2018 THITH_10790 22e0edb377f1dcf782b2e94c5d50dd14 360 SMART SM01329 3 351 8.2E-201 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 THITH_10790 22e0edb377f1dcf782b2e94c5d50dd14 360 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 3 350 2.5E-152 T 13-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 THITH_10790 22e0edb377f1dcf782b2e94c5d50dd14 360 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 2 355 51.324 T 13-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 THITH_10790 22e0edb377f1dcf782b2e94c5d50dd14 360 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 13-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 THITH_10790 22e0edb377f1dcf782b2e94c5d50dd14 360 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 350 5.6E-134 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 THITH_01280 40fdb29ef12606a9041a396475a9ea19 674 SUPERFAMILY SSF55729 367 512 5.15E-14 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_01280 40fdb29ef12606a9041a396475a9ea19 674 Pfam PF05127 Helicase 168 329 1.7E-40 T 13-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 THITH_01280 40fdb29ef12606a9041a396475a9ea19 674 SUPERFAMILY SSF52540 141 292 4.23E-12 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01280 40fdb29ef12606a9041a396475a9ea19 674 Gene3D G3DSA:1.20.120.890 540 672 2.8E-6 T 13-10-2018 IPR038321 TmcA, C-terminal domain superfamily THITH_01280 40fdb29ef12606a9041a396475a9ea19 674 Pfam PF17176 tRNA-binding domain 576 667 3.2E-8 T 13-10-2018 IPR033442 tRNA(Met) cytidine acetyltransferase TmcA, tRNA-binding domain THITH_01280 40fdb29ef12606a9041a396475a9ea19 674 Gene3D G3DSA:3.40.630.30 322 530 8.9E-53 T 13-10-2018 THITH_01280 40fdb29ef12606a9041a396475a9ea19 674 Gene3D G3DSA:3.40.50.11040 9 111 1.3E-11 T 13-10-2018 THITH_01280 40fdb29ef12606a9041a396475a9ea19 674 Gene3D G3DSA:3.40.50.12320 164 319 2.3E-35 T 13-10-2018 THITH_01280 40fdb29ef12606a9041a396475a9ea19 674 Pfam PF13718 GNAT acetyltransferase 2 365 475 2.3E-13 T 13-10-2018 IPR000182 GNAT domain THITH_01280 40fdb29ef12606a9041a396475a9ea19 674 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 10 668 38.547 T 13-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 THITH_04725 cde479c09aedd58f83fe8389740fba04 368 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 130 357 2.2E-62 T 13-10-2018 THITH_04725 cde479c09aedd58f83fe8389740fba04 368 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 142 2.6E-35 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_04725 cde479c09aedd58f83fe8389740fba04 368 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 322 342 2.6E-35 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_04725 cde479c09aedd58f83fe8389740fba04 368 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 205 2.6E-35 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_04725 cde479c09aedd58f83fe8389740fba04 368 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 241 257 2.6E-35 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_04725 cde479c09aedd58f83fe8389740fba04 368 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 268 287 2.6E-35 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_04725 cde479c09aedd58f83fe8389740fba04 368 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 289 306 2.6E-35 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_04725 cde479c09aedd58f83fe8389740fba04 368 SUPERFAMILY SSF51735 124 359 1.53E-80 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_04725 cde479c09aedd58f83fe8389740fba04 368 Gene3D G3DSA:3.40.50.720 1 109 9.6E-20 T 13-10-2018 THITH_04725 cde479c09aedd58f83fe8389740fba04 368 Gene3D G3DSA:3.40.50.720 118 367 2.5E-85 T 13-10-2018 THITH_04725 cde479c09aedd58f83fe8389740fba04 368 SUPERFAMILY SSF51735 2 120 4.69E-19 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_04725 cde479c09aedd58f83fe8389740fba04 368 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 194 205 3.8E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_04725 cde479c09aedd58f83fe8389740fba04 368 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 268 287 3.8E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_04725 cde479c09aedd58f83fe8389740fba04 368 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 247 255 3.8E-7 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_04725 cde479c09aedd58f83fe8389740fba04 368 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 124 300 1.0E-4 T 13-10-2018 THITH_14435 a7aaf7608b58210920575c2765903a79 385 PRINTS PR00423 Cell division protein FtsZ signature 213 234 9.5E-51 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THITH_14435 a7aaf7608b58210920575c2765903a79 385 PRINTS PR00423 Cell division protein FtsZ signature 99 119 9.5E-51 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THITH_14435 a7aaf7608b58210920575c2765903a79 385 PRINTS PR00423 Cell division protein FtsZ signature 127 148 9.5E-51 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THITH_14435 a7aaf7608b58210920575c2765903a79 385 PRINTS PR00423 Cell division protein FtsZ signature 190 212 9.5E-51 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THITH_14435 a7aaf7608b58210920575c2765903a79 385 Pfam PF12327 FtsZ family, C-terminal domain 223 317 1.1E-34 T 13-10-2018 IPR024757 Cell division protein FtsZ, C-terminal THITH_14435 a7aaf7608b58210920575c2765903a79 385 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 15 173 3.1E-39 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THITH_14435 a7aaf7608b58210920575c2765903a79 385 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 10 354 37.724 T 13-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 THITH_14435 a7aaf7608b58210920575c2765903a79 385 SUPERFAMILY SSF52490 14 209 4.97E-70 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 THITH_14435 a7aaf7608b58210920575c2765903a79 385 SUPERFAMILY SSF55307 205 320 3.89E-41 T 13-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 THITH_14435 a7aaf7608b58210920575c2765903a79 385 SMART SM00865 208 326 4.7E-53 T 13-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 THITH_14435 a7aaf7608b58210920575c2765903a79 385 SMART SM00864 14 206 1.0E-111 T 13-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 THITH_14435 a7aaf7608b58210920575c2765903a79 385 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 6 323 3.2E-130 T 13-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 THITH_14435 a7aaf7608b58210920575c2765903a79 385 ProSitePatterns PS01135 FtsZ protein signature 2. 98 119 - T 13-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 THITH_14435 a7aaf7608b58210920575c2765903a79 385 Gene3D G3DSA:3.30.1330.20 222 330 1.0E-33 T 13-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 THITH_14435 a7aaf7608b58210920575c2765903a79 385 Gene3D G3DSA:3.40.50.1440 5 221 2.5E-79 T 13-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 THITH_14435 a7aaf7608b58210920575c2765903a79 385 ProSitePatterns PS01134 FtsZ protein signature 1. 45 79 - T 13-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 THITH_16745 d9ac642a4deb24be383fb29b25748c46 339 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 103 1.5E-29 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_16745 d9ac642a4deb24be383fb29b25748c46 339 PIRSF PIRSF000149 1 337 4.7E-112 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_16745 d9ac642a4deb24be383fb29b25748c46 339 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 159 315 7.8E-56 T 13-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_16745 d9ac642a4deb24be383fb29b25748c46 339 SUPERFAMILY SSF51735 1 179 6.1E-53 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_16745 d9ac642a4deb24be383fb29b25748c46 339 Gene3D G3DSA:3.30.360.10 153 317 2.3E-125 T 13-10-2018 THITH_16745 d9ac642a4deb24be383fb29b25748c46 339 SUPERFAMILY SSF55347 154 316 3.57E-62 T 13-10-2018 THITH_16745 d9ac642a4deb24be383fb29b25748c46 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 148 166 3.1E-29 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_16745 d9ac642a4deb24be383fb29b25748c46 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 231 248 3.1E-29 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_16745 d9ac642a4deb24be383fb29b25748c46 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 3.1E-29 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_16745 d9ac642a4deb24be383fb29b25748c46 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 175 191 3.1E-29 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_16745 d9ac642a4deb24be383fb29b25748c46 339 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 271 286 3.1E-29 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_16745 d9ac642a4deb24be383fb29b25748c46 339 Gene3D G3DSA:3.40.50.720 4 329 2.3E-125 T 13-10-2018 THITH_16745 d9ac642a4deb24be383fb29b25748c46 339 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 152 159 - T 13-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_16745 d9ac642a4deb24be383fb29b25748c46 339 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 326 1.9E-114 T 13-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_16745 d9ac642a4deb24be383fb29b25748c46 339 SMART SM00846 3 154 1.3E-67 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_12435 e51046df2da214e773533d15021a78b3 199 SUPERFAMILY SSF55469 14 197 1.16E-30 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THITH_12435 e51046df2da214e773533d15021a78b3 199 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 34 194 7.0E-34 T 13-10-2018 IPR020051 SagB-type dehydrogenase domain THITH_12435 e51046df2da214e773533d15021a78b3 199 Gene3D G3DSA:3.40.109.10 1 195 1.2E-61 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THITH_12435 e51046df2da214e773533d15021a78b3 199 Pfam PF00881 Nitroreductase family 19 195 4.4E-26 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 THITH_07920 276e05955f964312cb783f085dde15ec 777 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 125 729 6.8E-90 T 13-10-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 THITH_07920 276e05955f964312cb783f085dde15ec 777 SMART SM00849 516 675 1.6E-9 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_07920 276e05955f964312cb783f085dde15ec 777 SUPERFAMILY SSF56281 508 734 6.77E-38 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_07920 276e05955f964312cb783f085dde15ec 777 Pfam PF00753 Metallo-beta-lactamase superfamily 513 691 8.2E-11 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_07920 276e05955f964312cb783f085dde15ec 777 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 234 411 1.9E-19 T 13-10-2018 IPR004477 ComEC/Rec2-related protein THITH_07920 276e05955f964312cb783f085dde15ec 777 Pfam PF03772 Competence protein 212 480 3.7E-55 T 13-10-2018 IPR004477 ComEC/Rec2-related protein THITH_07920 276e05955f964312cb783f085dde15ec 777 Pfam PF13567 Domain of unknown function (DUF4131) 21 168 6.6E-25 T 13-10-2018 IPR025405 Domain of unknown function DUF4131 THITH_07920 276e05955f964312cb783f085dde15ec 777 Gene3D G3DSA:3.60.15.10 508 734 9.3E-40 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_10825 1fed690df9789935ef78b650cebd99c9 595 SUPERFAMILY SSF52402 234 566 1.87E-71 T 13-10-2018 THITH_10825 1fed690df9789935ef78b650cebd99c9 595 TIGRFAM TIGR03104 trio_amidotrans: asparagine synthase family amidotransferase 1 591 6.0E-272 T 13-10-2018 IPR017535 Asparagine synthase family amidotransferase THITH_10825 1fed690df9789935ef78b650cebd99c9 595 Pfam PF00733 Asparagine synthase 243 589 5.8E-84 T 13-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 THITH_10825 1fed690df9789935ef78b650cebd99c9 595 Gene3D G3DSA:3.60.20.10 6 179 3.9E-60 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_10825 1fed690df9789935ef78b650cebd99c9 595 Pfam PF13537 Glutamine amidotransferase domain 47 166 8.7E-44 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain THITH_10825 1fed690df9789935ef78b650cebd99c9 595 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 522 6.0E-131 T 13-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THITH_10825 1fed690df9789935ef78b650cebd99c9 595 PIRSF PIRSF001589 1 595 1.1E-192 T 13-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THITH_10825 1fed690df9789935ef78b650cebd99c9 595 SUPERFAMILY SSF56235 1 224 1.12E-62 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 443 46.074 T 13-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 Gene3D G3DSA:3.40.120.10 1 152 1.4E-47 T 13-10-2018 THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 SUPERFAMILY SSF53738 154 255 1.41E-27 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 Gene3D G3DSA:3.40.120.10 255 337 6.5E-60 T 13-10-2018 THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 232 247 5.3E-13 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 5.3E-13 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 5.3E-13 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 13-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 SUPERFAMILY SSF53738 256 362 1.96E-28 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 441 2.2E-178 T 13-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 SUPERFAMILY SSF55957 356 444 6.15E-20 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 SUPERFAMILY SSF53738 3 179 3.53E-48 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 133 2.2E-43 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 371 432 2.2E-13 T 13-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 256 365 2.6E-28 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 Gene3D G3DSA:3.30.310.50 368 446 6.6E-23 T 13-10-2018 THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 Gene3D G3DSA:3.40.120.10 172 360 6.5E-60 T 13-10-2018 THITH_13010 a7f0ae57fe33bfd376ef538f7e9598ea 456 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 155 252 6.2E-18 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_11090 6bb038b3e5bd1b86937e63a4c565ff11 80 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 68 1.5E-14 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THITH_11090 6bb038b3e5bd1b86937e63a4c565ff11 80 SUPERFAMILY SSF143120 1 79 2.09E-16 T 13-10-2018 IPR036165 YefM-like superfamily THITH_11090 6bb038b3e5bd1b86937e63a4c565ff11 80 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 54 7.2E-7 T 13-10-2018 THITH_11090 6bb038b3e5bd1b86937e63a4c565ff11 80 Gene3D G3DSA:3.40.1620.40 3 67 1.2E-19 T 13-10-2018 THITH_06830 3828c310da924b583caba2398a07aa6f 124 Pfam PF07238 PilZ domain 8 99 3.5E-5 T 13-10-2018 IPR009875 PilZ domain GO:0035438 THITH_00650 20cab069e894d38e74e78a4dabb83f03 439 Gene3D G3DSA:2.40.50.100 66 101 4.2E-7 T 13-10-2018 THITH_00650 20cab069e894d38e74e78a4dabb83f03 439 Pfam PF13437 HlyD family secretion protein 294 405 8.5E-15 T 13-10-2018 THITH_00650 20cab069e894d38e74e78a4dabb83f03 439 TIGRFAM TIGR01843 type_I_hlyD: type I secretion membrane fusion protein, HlyD family 29 439 5.5E-114 T 13-10-2018 IPR010129 Type I secretion membrane fusion protein, HlyD family GO:0015031|GO:0016021 THITH_00650 20cab069e894d38e74e78a4dabb83f03 439 Pfam PF13533 Biotin-lipoyl like 73 108 5.5E-7 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain THITH_00650 20cab069e894d38e74e78a4dabb83f03 439 SUPERFAMILY SSF111369 76 130 2.35E-6 T 13-10-2018 THITH_00650 20cab069e894d38e74e78a4dabb83f03 439 ProSitePatterns PS00543 HlyD family secretion proteins signature. 403 425 - T 13-10-2018 IPR006144 Secretion protein HlyD, conserved site GO:0008565|GO:0009306|GO:0016020 THITH_00650 20cab069e894d38e74e78a4dabb83f03 439 Gene3D G3DSA:1.10.287.470 102 130 4.2E-7 T 13-10-2018 THITH_00650 20cab069e894d38e74e78a4dabb83f03 439 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 306 327 3.7E-41 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THITH_00650 20cab069e894d38e74e78a4dabb83f03 439 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 37 60 3.7E-41 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THITH_00650 20cab069e894d38e74e78a4dabb83f03 439 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 79 99 3.7E-41 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THITH_00650 20cab069e894d38e74e78a4dabb83f03 439 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 363 386 3.7E-41 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THITH_00650 20cab069e894d38e74e78a4dabb83f03 439 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 339 363 3.7E-41 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THITH_00650 20cab069e894d38e74e78a4dabb83f03 439 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 403 418 3.7E-41 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THITH_00650 20cab069e894d38e74e78a4dabb83f03 439 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 418 438 3.7E-41 T 13-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 THITH_00010 2e9b0a2cfbfba1755c6c06fc7fb229e5 366 Gene3D G3DSA:3.70.10.10 137 364 3.0E-99 T 13-10-2018 THITH_00010 2e9b0a2cfbfba1755c6c06fc7fb229e5 366 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 246 365 2.8E-29 T 13-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 THITH_00010 2e9b0a2cfbfba1755c6c06fc7fb229e5 366 Pfam PF02767 DNA polymerase III beta subunit, central domain 129 243 1.2E-31 T 13-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 THITH_00010 2e9b0a2cfbfba1755c6c06fc7fb229e5 366 SUPERFAMILY SSF55979 245 366 3.45E-32 T 13-10-2018 THITH_00010 2e9b0a2cfbfba1755c6c06fc7fb229e5 366 SMART SM00480 17 362 1.9E-88 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 THITH_00010 2e9b0a2cfbfba1755c6c06fc7fb229e5 366 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 366 3.2E-87 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 THITH_00010 2e9b0a2cfbfba1755c6c06fc7fb229e5 366 PIRSF PIRSF000804 1 366 7.9E-100 T 13-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 THITH_00010 2e9b0a2cfbfba1755c6c06fc7fb229e5 366 SUPERFAMILY SSF55979 1 118 8.64E-16 T 13-10-2018 THITH_00010 2e9b0a2cfbfba1755c6c06fc7fb229e5 366 Gene3D G3DSA:3.10.150.10 1 242 3.0E-99 T 13-10-2018 THITH_00010 2e9b0a2cfbfba1755c6c06fc7fb229e5 366 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 117 2.9E-17 T 13-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 THITH_00010 2e9b0a2cfbfba1755c6c06fc7fb229e5 366 SUPERFAMILY SSF55979 127 244 9.42E-25 T 13-10-2018 THITH_05395 0fec6783872757d6484c684cb8603555 266 SMART SM00382 34 217 3.8E-20 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_05395 0fec6783872757d6484c684cb8603555 266 TIGRFAM TIGR01184 ntrCD: nitrate ABC transporter, ATP-binding proteins C and D 25 255 5.3E-104 T 13-10-2018 IPR005890 Nitrate transport ATP-binding subunit C/D GO:0015112|GO:0015706|GO:0016020 THITH_05395 0fec6783872757d6484c684cb8603555 266 Gene3D G3DSA:3.40.50.300 3 256 9.1E-62 T 13-10-2018 THITH_05395 0fec6783872757d6484c684cb8603555 266 Pfam PF00005 ABC transporter 25 167 3.5E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_05395 0fec6783872757d6484c684cb8603555 266 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_05395 0fec6783872757d6484c684cb8603555 266 SUPERFAMILY SSF52540 6 232 2.54E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 SUPERFAMILY SSF55874 3 213 8.51E-66 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 Gene3D G3DSA:3.30.565.10 1 213 5.5E-75 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR01098 Topoisomerase IV subunit B signature 147 162 1.0E-106 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR01098 Topoisomerase IV subunit B signature 24 37 1.0E-106 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR01098 Topoisomerase IV subunit B signature 360 385 1.0E-106 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR01098 Topoisomerase IV subunit B signature 446 467 1.0E-106 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR01098 Topoisomerase IV subunit B signature 190 211 1.0E-106 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR01098 Topoisomerase IV subunit B signature 336 359 1.0E-106 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR01098 Topoisomerase IV subunit B signature 535 557 1.0E-106 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR01098 Topoisomerase IV subunit B signature 467 479 1.0E-106 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR01098 Topoisomerase IV subunit B signature 172 189 1.0E-106 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR01098 Topoisomerase IV subunit B signature 236 259 1.0E-106 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR01098 Topoisomerase IV subunit B signature 292 308 1.0E-106 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR01098 Topoisomerase IV subunit B signature 501 517 1.0E-106 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR01098 Topoisomerase IV subunit B signature 133 147 1.0E-106 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR01098 Topoisomerase IV subunit B signature 309 324 1.0E-106 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 Pfam PF01751 Toprim domain 411 520 3.6E-13 T 13-10-2018 IPR006171 TOPRIM domain THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 SMART SM00433 32 622 5.6E-207 T 13-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 SMART SM00387 25 171 6.1E-19 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 556 618 1.0E-22 T 13-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 Pfam PF00204 DNA gyrase B 216 381 2.0E-41 T 13-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 26 168 3.3E-17 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 ProSitePatterns PS00177 DNA topoisomerase II signature. 414 422 - T 13-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 Hamap MF_00938 DNA topoisomerase 4 subunit B [parE]. 1 626 46.257 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 SUPERFAMILY SSF56719 386 619 2.22E-77 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR00418 DNA topoisomerase II family signature 64 77 3.7E-58 T 13-10-2018 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR00418 DNA topoisomerase II family signature 29 44 3.7E-58 T 13-10-2018 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR00418 DNA topoisomerase II family signature 477 493 3.7E-58 T 13-10-2018 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR00418 DNA topoisomerase II family signature 495 512 3.7E-58 T 13-10-2018 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR00418 DNA topoisomerase II family signature 515 527 3.7E-58 T 13-10-2018 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR00418 DNA topoisomerase II family signature 560 576 3.7E-58 T 13-10-2018 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR00418 DNA topoisomerase II family signature 107 121 3.7E-58 T 13-10-2018 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR00418 DNA topoisomerase II family signature 412 426 3.7E-58 T 13-10-2018 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 PRINTS PR00418 DNA topoisomerase II family signature 264 277 3.7E-58 T 13-10-2018 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 Gene3D G3DSA:3.30.230.10 214 387 7.2E-58 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 TIGRFAM TIGR01055 parE_Gneg: DNA topoisomerase IV, B subunit 2 622 1.9E-301 T 13-10-2018 IPR005737 DNA topoisomerase IV, subunit B, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 Gene3D G3DSA:3.40.50.670 388 621 1.3E-86 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THITH_13490 84e27aa5e92c4252073baed3f2eca344 626 SUPERFAMILY SSF54211 215 380 5.69E-47 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_01160 ec427e607c1e57f9f9031f6096ac213b 725 Gene3D G3DSA:3.40.50.300 515 716 1.4E-33 T 13-10-2018 THITH_01160 ec427e607c1e57f9f9031f6096ac213b 725 SUPERFAMILY SSF52540 234 701 2.92E-75 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01160 ec427e607c1e57f9f9031f6096ac213b 725 Pfam PF13361 UvrD-like helicase C-terminal domain 623 698 3.9E-13 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 THITH_01160 ec427e607c1e57f9f9031f6096ac213b 725 SUPERFAMILY SSF143011 4 90 4.12E-6 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_01160 ec427e607c1e57f9f9031f6096ac213b 725 Pfam PF13245 AAA domain 248 494 6.0E-17 T 13-10-2018 THITH_01160 ec427e607c1e57f9f9031f6096ac213b 725 Pfam PF13361 UvrD-like helicase C-terminal domain 512 615 3.9E-7 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 THITH_06460 8bfe47f599c4bd1a4362923192e0b161 243 Pfam PF00027 Cyclic nucleotide-binding domain 39 118 2.4E-13 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain THITH_06460 8bfe47f599c4bd1a4362923192e0b161 243 SMART SM00100 19 140 4.4E-16 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain THITH_06460 8bfe47f599c4bd1a4362923192e0b161 243 SMART SM00419 176 224 4.1E-13 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THITH_06460 8bfe47f599c4bd1a4362923192e0b161 243 SUPERFAMILY SSF46785 154 233 3.54E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_06460 8bfe47f599c4bd1a4362923192e0b161 243 Gene3D G3DSA:1.10.10.10 154 235 5.0E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_06460 8bfe47f599c4bd1a4362923192e0b161 243 Pfam PF13545 Crp-like helix-turn-helix domain 157 231 1.8E-17 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THITH_06460 8bfe47f599c4bd1a4362923192e0b161 243 SUPERFAMILY SSF51206 12 151 1.7E-27 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like THITH_06460 8bfe47f599c4bd1a4362923192e0b161 243 Gene3D G3DSA:2.60.120.10 32 153 3.2E-41 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_06460 8bfe47f599c4bd1a4362923192e0b161 243 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 198 213 2.7E-10 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THITH_06460 8bfe47f599c4bd1a4362923192e0b161 243 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 182 198 2.7E-10 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THITH_06235 c0a96e1f624787cc2a3c76464debbf1c 119 SUPERFAMILY SSF74731 2 117 2.09E-49 T 13-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_06235 c0a96e1f624787cc2a3c76464debbf1c 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 29.041 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_06235 c0a96e1f624787cc2a3c76464debbf1c 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 1.2E-48 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_06235 c0a96e1f624787cc2a3c76464debbf1c 119 Gene3D G3DSA:1.10.1900.20 56 118 2.3E-25 T 13-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_06235 c0a96e1f624787cc2a3c76464debbf1c 119 Pfam PF00453 Ribosomal protein L20 3 108 2.3E-48 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_06235 c0a96e1f624787cc2a3c76464debbf1c 119 Gene3D G3DSA:1.10.720.90 2 55 3.8E-26 T 13-10-2018 THITH_06235 c0a96e1f624787cc2a3c76464debbf1c 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_06235 c0a96e1f624787cc2a3c76464debbf1c 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 71 1.0E-18 T 13-10-2018 THITH_06235 c0a96e1f624787cc2a3c76464debbf1c 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 2.6E-40 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_06235 c0a96e1f624787cc2a3c76464debbf1c 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 2.6E-40 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_06235 c0a96e1f624787cc2a3c76464debbf1c 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 2.6E-40 T 13-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_12680 5f66e92cf0a820111c813bc604bb6173 1033 Gene3D G3DSA:1.25.40.10 473 798 1.2E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_12680 5f66e92cf0a820111c813bc604bb6173 1033 SUPERFAMILY SSF52540 28 195 3.42E-9 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_12680 5f66e92cf0a820111c813bc604bb6173 1033 Gene3D G3DSA:1.25.40.10 911 1031 2.7E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_12680 5f66e92cf0a820111c813bc604bb6173 1033 Gene3D G3DSA:1.10.10.10 817 908 1.3E-11 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_12680 5f66e92cf0a820111c813bc604bb6173 1033 Gene3D G3DSA:3.40.50.300 18 160 6.7E-10 T 13-10-2018 THITH_12680 5f66e92cf0a820111c813bc604bb6173 1033 SMART SM01043 912 1032 2.4E-8 T 13-10-2018 IPR005158 Bacterial transcriptional activator domain THITH_12680 5f66e92cf0a820111c813bc604bb6173 1033 SUPERFAMILY SSF46894 820 892 8.93E-6 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THITH_12680 5f66e92cf0a820111c813bc604bb6173 1033 SUPERFAMILY SSF48452 910 1030 8.35E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_12680 5f66e92cf0a820111c813bc604bb6173 1033 Pfam PF03704 Bacterial transcriptional activator domain 912 1030 8.3E-11 T 13-10-2018 IPR005158 Bacterial transcriptional activator domain THITH_03040 7a271d827e745b72aea49acc6f16f38a 322 SMART SM00849 63 250 1.6E-12 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_03040 7a271d827e745b72aea49acc6f16f38a 322 SUPERFAMILY SSF56281 12 298 8.38E-45 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_03040 7a271d827e745b72aea49acc6f16f38a 322 Gene3D G3DSA:3.60.15.10 25 275 1.9E-37 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_03040 7a271d827e745b72aea49acc6f16f38a 322 Pfam PF00753 Metallo-beta-lactamase superfamily 63 250 8.2E-11 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_07925 da92a3a20309571b12205371820fceb1 354 Pfam PF01008 Initiation factor 2 subunit family 51 337 1.3E-75 T 13-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 THITH_07925 da92a3a20309571b12205371820fceb1 354 Gene3D G3DSA:1.20.120.1840 8 188 7.0E-54 T 13-10-2018 THITH_07925 da92a3a20309571b12205371820fceb1 354 Gene3D G3DSA:3.40.50.10470 189 344 1.1E-48 T 13-10-2018 THITH_07925 da92a3a20309571b12205371820fceb1 354 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 39 337 1.3E-110 T 13-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 THITH_07925 da92a3a20309571b12205371820fceb1 354 SUPERFAMILY SSF100950 5 342 5.23E-114 T 13-10-2018 IPR037171 NagB/RpiA transferase-like THITH_07925 da92a3a20309571b12205371820fceb1 354 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 11 337 4.2E-135 T 13-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 THITH_07925 da92a3a20309571b12205371820fceb1 354 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 8 348 39.63 T 13-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 THITH_17090 a4e5c87d8cec3fc1280fd16bbb5834c4 146 Gene3D G3DSA:2.20.28.140 5 39 2.9E-8 T 13-10-2018 THITH_17090 a4e5c87d8cec3fc1280fd16bbb5834c4 146 ProSitePatterns PS00194 Thioredoxin family active site. 62 80 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 THITH_17090 a4e5c87d8cec3fc1280fd16bbb5834c4 146 Pfam PF00085 Thioredoxin 51 141 1.8E-24 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 THITH_17090 a4e5c87d8cec3fc1280fd16bbb5834c4 146 SUPERFAMILY SSF52833 30 144 4.36E-32 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_17090 a4e5c87d8cec3fc1280fd16bbb5834c4 146 PIRSF PIRSF000077 42 144 8.9E-27 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THITH_17090 a4e5c87d8cec3fc1280fd16bbb5834c4 146 Gene3D G3DSA:3.40.30.10 44 144 7.5E-27 T 13-10-2018 THITH_17090 a4e5c87d8cec3fc1280fd16bbb5834c4 146 PRINTS PR00421 Thioredoxin family signature 69 78 8.3E-8 T 13-10-2018 THITH_17090 a4e5c87d8cec3fc1280fd16bbb5834c4 146 PRINTS PR00421 Thioredoxin family signature 109 120 8.3E-8 T 13-10-2018 THITH_17090 a4e5c87d8cec3fc1280fd16bbb5834c4 146 PRINTS PR00421 Thioredoxin family signature 61 69 8.3E-8 T 13-10-2018 THITH_10425 93e046c903f8c428152af5944342904f 453 Pfam PF02163 Peptidase family M50 9 438 3.3E-73 T 13-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 THITH_10425 93e046c903f8c428152af5944342904f 453 Pfam PF13180 PDZ domain 223 287 3.4E-10 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_10425 93e046c903f8c428152af5944342904f 453 SMART SM00228 107 187 1.4E-5 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_10425 93e046c903f8c428152af5944342904f 453 SMART SM00228 211 280 2.5E-9 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_10425 93e046c903f8c428152af5944342904f 453 SUPERFAMILY SSF50156 89 193 1.3E-14 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 THITH_10425 93e046c903f8c428152af5944342904f 453 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 1 452 8.9E-118 T 13-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 THITH_10425 93e046c903f8c428152af5944342904f 453 Gene3D G3DSA:2.30.42.10 221 310 9.5E-23 T 13-10-2018 THITH_10425 93e046c903f8c428152af5944342904f 453 SUPERFAMILY SSF50156 225 311 1.58E-17 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 THITH_10425 93e046c903f8c428152af5944342904f 453 Gene3D G3DSA:2.30.42.10 127 220 1.1E-18 T 13-10-2018 THITH_13105 c155e1a0877eb6bba961a1c0494192d4 363 Gene3D G3DSA:3.20.20.70 55 338 3.2E-83 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_13105 c155e1a0877eb6bba961a1c0494192d4 363 SUPERFAMILY SSF102114 107 328 5.36E-23 T 13-10-2018 THITH_13105 c155e1a0877eb6bba961a1c0494192d4 363 TIGRFAM TIGR00238 TIGR00238: KamA family protein 19 332 4.9E-88 T 13-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase THITH_13105 c155e1a0877eb6bba961a1c0494192d4 363 Pfam PF13394 4Fe-4S single cluster domain 120 188 9.1E-7 T 13-10-2018 THITH_13105 c155e1a0877eb6bba961a1c0494192d4 363 Pfam PF04055 Radical SAM superfamily 120 207 1.7E-8 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THITH_13105 c155e1a0877eb6bba961a1c0494192d4 363 PIRSF PIRSF004911 7 350 4.7E-106 T 13-10-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase THITH_13105 c155e1a0877eb6bba961a1c0494192d4 363 TIGRFAM TIGR03821 EFP_modif_epmB: EF-P beta-lysylation protein EpmB 20 339 2.5E-133 T 13-10-2018 IPR022462 Lysine-2,3-aminomutase-like THITH_15720 ecd9bdc123af767a3cc4ba4ef2e5db3b 173 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 25 1.4E-6 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_15720 ecd9bdc123af767a3cc4ba4ef2e5db3b 173 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 26 5.7E-5 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_15720 ecd9bdc123af767a3cc4ba4ef2e5db3b 173 Pfam PF12019 Type II transport protein GspH 42 163 3.6E-24 T 13-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 THITH_15720 ecd9bdc123af767a3cc4ba4ef2e5db3b 173 SUPERFAMILY SSF54523 8 95 6.83E-19 T 13-10-2018 THITH_15720 ecd9bdc123af767a3cc4ba4ef2e5db3b 173 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_15720 ecd9bdc123af767a3cc4ba4ef2e5db3b 173 Gene3D G3DSA:3.30.700.10 8 172 2.0E-12 T 13-10-2018 THITH_15860 91242378ab430a76b7b7bdf8f67fd9a0 197 SUPERFAMILY SSF52317 1 193 3.12E-55 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_15860 91242378ab430a76b7b7bdf8f67fd9a0 197 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 192 1.2E-84 T 13-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THITH_15860 91242378ab430a76b7b7bdf8f67fd9a0 197 PRINTS PR00097 Anthranilate synthase component II signature 99 107 1.1E-36 T 13-10-2018 THITH_15860 91242378ab430a76b7b7bdf8f67fd9a0 197 PRINTS PR00097 Anthranilate synthase component II signature 119 131 1.1E-36 T 13-10-2018 THITH_15860 91242378ab430a76b7b7bdf8f67fd9a0 197 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.1E-36 T 13-10-2018 THITH_15860 91242378ab430a76b7b7bdf8f67fd9a0 197 PRINTS PR00097 Anthranilate synthase component II signature 47 56 1.1E-36 T 13-10-2018 THITH_15860 91242378ab430a76b7b7bdf8f67fd9a0 197 PRINTS PR00097 Anthranilate synthase component II signature 169 182 1.1E-36 T 13-10-2018 THITH_15860 91242378ab430a76b7b7bdf8f67fd9a0 197 PRINTS PR00097 Anthranilate synthase component II signature 2 16 1.1E-36 T 13-10-2018 THITH_15860 91242378ab430a76b7b7bdf8f67fd9a0 197 Gene3D G3DSA:3.40.50.880 1 192 6.6E-61 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_15860 91242378ab430a76b7b7bdf8f67fd9a0 197 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 4.7E-7 T 13-10-2018 THITH_15860 91242378ab430a76b7b7bdf8f67fd9a0 197 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 4.7E-7 T 13-10-2018 THITH_15860 91242378ab430a76b7b7bdf8f67fd9a0 197 Pfam PF00117 Glutamine amidotransferase class-I 4 191 2.6E-54 T 13-10-2018 IPR017926 Glutamine amidotransferase THITH_15860 91242378ab430a76b7b7bdf8f67fd9a0 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 1.0E-13 T 13-10-2018 THITH_15860 91242378ab430a76b7b7bdf8f67fd9a0 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.0E-13 T 13-10-2018 THITH_15860 91242378ab430a76b7b7bdf8f67fd9a0 197 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.0E-13 T 13-10-2018 THITH_10595 7ee51d7f6a2607cf39785c1f674536af 255 SUPERFAMILY SSF54292 16 117 1.31E-25 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 THITH_10595 7ee51d7f6a2607cf39785c1f674536af 255 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 20 122 1.6E-28 T 13-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_10595 7ee51d7f6a2607cf39785c1f674536af 255 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 22 242 3.4E-52 T 13-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_10595 7ee51d7f6a2607cf39785c1f674536af 255 Gene3D G3DSA:3.10.20.30 9 118 1.0E-30 T 13-10-2018 IPR012675 Beta-grasp domain superfamily THITH_10595 7ee51d7f6a2607cf39785c1f674536af 255 SUPERFAMILY SSF46548 122 248 3.66E-24 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_10595 7ee51d7f6a2607cf39785c1f674536af 255 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 163 174 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_10595 7ee51d7f6a2607cf39785c1f674536af 255 Gene3D G3DSA:1.10.1060.10 119 252 3.7E-46 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_10595 7ee51d7f6a2607cf39785c1f674536af 255 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 70 78 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THITH_10595 7ee51d7f6a2607cf39785c1f674536af 255 Pfam PF13183 4Fe-4S dicluster domain 159 233 5.1E-9 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_13145 d62011ee6c43054d76290179a0d0ce5f 574 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 515 3.1E-14 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal THITH_13145 d62011ee6c43054d76290179a0d0ce5f 574 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 559 3.6E-152 T 13-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 THITH_13145 d62011ee6c43054d76290179a0d0ce5f 574 PIRSF PIRSF003128 1 563 2.4E-150 T 13-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 THITH_13145 d62011ee6c43054d76290179a0d0ce5f 574 Gene3D G3DSA:3.40.50.300 278 559 1.3E-50 T 13-10-2018 THITH_13145 d62011ee6c43054d76290179a0d0ce5f 574 Gene3D G3DSA:3.40.50.300 1 277 1.8E-42 T 13-10-2018 THITH_13145 d62011ee6c43054d76290179a0d0ce5f 574 SUPERFAMILY SSF52540 1 515 6.19E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_09745 791c288605efdeae5a1db05ec5d8eb7a 244 Gene3D G3DSA:3.90.550.10 1 232 2.4E-35 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_09745 791c288605efdeae5a1db05ec5d8eb7a 244 Pfam PF00535 Glycosyl transferase family 2 12 135 4.6E-17 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THITH_09745 791c288605efdeae5a1db05ec5d8eb7a 244 SUPERFAMILY SSF53448 10 217 1.45E-28 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_15935 d7563805859aec706f6927ab2eb8cb06 479 Gene3D G3DSA:2.40.33.10 70 168 2.2E-163 T 13-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THITH_15935 d7563805859aec706f6927ab2eb8cb06 479 SUPERFAMILY SSF52935 345 473 3.79E-38 T 13-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THITH_15935 d7563805859aec706f6927ab2eb8cb06 479 Pfam PF02887 Pyruvate kinase, alpha/beta domain 356 470 7.5E-32 T 13-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THITH_15935 d7563805859aec706f6927ab2eb8cb06 479 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 472 6.6E-162 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THITH_15935 d7563805859aec706f6927ab2eb8cb06 479 Gene3D G3DSA:3.40.1380.20 335 468 2.2E-163 T 13-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THITH_15935 d7563805859aec706f6927ab2eb8cb06 479 SUPERFAMILY SSF51621 1 339 2.23E-93 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 THITH_15935 d7563805859aec706f6927ab2eb8cb06 479 PRINTS PR01050 Pyruvate kinase family signature 243 267 3.3E-57 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THITH_15935 d7563805859aec706f6927ab2eb8cb06 479 PRINTS PR01050 Pyruvate kinase family signature 268 292 3.3E-57 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THITH_15935 d7563805859aec706f6927ab2eb8cb06 479 PRINTS PR01050 Pyruvate kinase family signature 59 75 3.3E-57 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THITH_15935 d7563805859aec706f6927ab2eb8cb06 479 PRINTS PR01050 Pyruvate kinase family signature 293 311 3.3E-57 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THITH_15935 d7563805859aec706f6927ab2eb8cb06 479 PRINTS PR01050 Pyruvate kinase family signature 216 242 3.3E-57 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THITH_15935 d7563805859aec706f6927ab2eb8cb06 479 PRINTS PR01050 Pyruvate kinase family signature 186 200 3.3E-57 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THITH_15935 d7563805859aec706f6927ab2eb8cb06 479 PRINTS PR01050 Pyruvate kinase family signature 312 328 3.3E-57 T 13-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THITH_15935 d7563805859aec706f6927ab2eb8cb06 479 Pfam PF00224 Pyruvate kinase, barrel domain 1 337 4.1E-124 T 13-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THITH_15935 d7563805859aec706f6927ab2eb8cb06 479 SUPERFAMILY SSF50800 70 165 5.58E-24 T 13-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily THITH_15935 d7563805859aec706f6927ab2eb8cb06 479 Gene3D G3DSA:3.20.20.60 2 334 2.2E-163 T 13-10-2018 THITH_07590 467a0d9571ea39de7ee60449881b323b 265 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_07590 467a0d9571ea39de7ee60449881b323b 265 SUPERFAMILY SSF52540 27 224 1.28E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_07590 467a0d9571ea39de7ee60449881b323b 265 Gene3D G3DSA:3.40.50.300 6 253 1.2E-60 T 13-10-2018 THITH_07590 467a0d9571ea39de7ee60449881b323b 265 SMART SM00382 30 220 1.0E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_07590 467a0d9571ea39de7ee60449881b323b 265 Pfam PF00005 ABC transporter 27 170 5.6E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_13130 14d42eac4a713c907dfcbe81040e4cdd 194 Gene3D G3DSA:3.90.20.20 26 128 4.4E-27 T 13-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 THITH_13130 14d42eac4a713c907dfcbe81040e4cdd 194 Gene3D G3DSA:2.30.22.10 129 185 1.3E-24 T 13-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 THITH_13130 14d42eac4a713c907dfcbe81040e4cdd 194 SUPERFAMILY SSF58014 35 129 7.98E-25 T 13-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 THITH_13130 14d42eac4a713c907dfcbe81040e4cdd 194 Pfam PF01025 GrpE 25 184 1.8E-51 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THITH_13130 14d42eac4a713c907dfcbe81040e4cdd 194 PRINTS PR00773 GrpE protein signature 137 152 1.0E-23 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THITH_13130 14d42eac4a713c907dfcbe81040e4cdd 194 PRINTS PR00773 GrpE protein signature 164 183 1.0E-23 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THITH_13130 14d42eac4a713c907dfcbe81040e4cdd 194 PRINTS PR00773 GrpE protein signature 55 71 1.0E-23 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THITH_13130 14d42eac4a713c907dfcbe81040e4cdd 194 PRINTS PR00773 GrpE protein signature 83 98 1.0E-23 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THITH_13130 14d42eac4a713c907dfcbe81040e4cdd 194 Hamap MF_01151 Protein GrpE [grpE]. 3 185 20.425 T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THITH_13130 14d42eac4a713c907dfcbe81040e4cdd 194 ProSitePatterns PS01071 grpE protein signature. 140 183 - T 13-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 THITH_13130 14d42eac4a713c907dfcbe81040e4cdd 194 SUPERFAMILY SSF51064 130 186 1.31E-18 T 13-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 THITH_04765 376ba729c67381cd4992464a75c646fc 323 Gene3D G3DSA:3.40.109.10 5 102 2.4E-29 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THITH_04765 376ba729c67381cd4992464a75c646fc 323 Gene3D G3DSA:3.40.109.10 105 322 1.5E-56 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THITH_04765 376ba729c67381cd4992464a75c646fc 323 SUPERFAMILY SSF55469 12 85 1.96E-8 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THITH_04765 376ba729c67381cd4992464a75c646fc 323 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 205 222 - T 13-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site THITH_04765 376ba729c67381cd4992464a75c646fc 323 SUPERFAMILY SSF55469 117 322 7.85E-12 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THITH_16240 1fe14590a53d550756fae73afffdee68 316 Pfam PF03466 LysR substrate binding domain 87 298 1.0E-47 T 13-10-2018 IPR005119 LysR, substrate-binding THITH_16240 1fe14590a53d550756fae73afffdee68 316 Gene3D G3DSA:1.10.10.10 1 84 1.0E-30 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_16240 1fe14590a53d550756fae73afffdee68 316 SUPERFAMILY SSF46785 1 110 3.97E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_16240 1fe14590a53d550756fae73afffdee68 316 Gene3D G3DSA:3.40.190.10 92 294 1.5E-78 T 13-10-2018 THITH_16240 1fe14590a53d550756fae73afffdee68 316 Gene3D G3DSA:3.40.190.10 161 271 1.5E-78 T 13-10-2018 THITH_16240 1fe14590a53d550756fae73afffdee68 316 SUPERFAMILY SSF53850 87 299 5.43E-43 T 13-10-2018 THITH_16240 1fe14590a53d550756fae73afffdee68 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 7.5E-10 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_16240 1fe14590a53d550756fae73afffdee68 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 7.5E-10 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_16240 1fe14590a53d550756fae73afffdee68 316 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 7.5E-10 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_16240 1fe14590a53d550756fae73afffdee68 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 1.5E-20 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_16135 42c679be4f5e4efeeae3fe0740075e97 536 TIGRFAM TIGR01434 glu_cys_ligase: glutamate--cysteine ligase 28 519 7.0E-161 T 13-10-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 THITH_16135 42c679be4f5e4efeeae3fe0740075e97 536 SUPERFAMILY SSF55931 19 518 1.37E-167 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 THITH_16135 42c679be4f5e4efeeae3fe0740075e97 536 Pfam PF04262 Glutamate-cysteine ligase 25 383 2.6E-147 T 13-10-2018 IPR007370 Glutamate--cysteine ligase GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 THITH_16135 42c679be4f5e4efeeae3fe0740075e97 536 Hamap MF_00578 Glutamate--cysteine ligase [gshA]. 1 536 176.826 T 13-10-2018 IPR006334 Glutamate--cysteine ligase, monofunctional GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 THITH_16135 42c679be4f5e4efeeae3fe0740075e97 536 Gene3D G3DSA:3.30.590.20 22 526 6.1E-174 T 13-10-2018 THITH_03980 fccc498c5daa1f34eccf19c9e6d8d4a7 299 SUPERFAMILY SSF56176 1 43 4.02E-12 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 THITH_03980 fccc498c5daa1f34eccf19c9e6d8d4a7 299 Gene3D G3DSA:3.30.465.10 1 42 7.8E-61 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 THITH_03980 fccc498c5daa1f34eccf19c9e6d8d4a7 299 Gene3D G3DSA:3.40.462.20 43 218 7.8E-61 T 13-10-2018 THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 SUPERFAMILY SSF50465 304 396 2.04E-36 T 13-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 Pfam PF03144 Elongation factor Tu domain 2 227 296 1.8E-19 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 146 9.8E-15 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 Gene3D G3DSA:2.40.30.10 340 395 2.4E-30 T 13-10-2018 THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 396 4.4E-230 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 Pfam PF03143 Elongation factor Tu C-terminal domain 300 394 5.5E-34 T 13-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 396 60.495 T 13-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 Gene3D G3DSA:3.40.50.300 1 205 5.1E-72 T 13-10-2018 THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 SUPERFAMILY SSF50447 207 303 8.84E-32 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 SUPERFAMILY SSF52540 6 221 1.63E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 Gene3D G3DSA:2.40.30.10 208 336 9.3E-54 T 13-10-2018 THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 1.6E-59 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 PRINTS PR00315 GTP-binding elongation factor signature 94 105 9.6E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 PRINTS PR00315 GTP-binding elongation factor signature 58 66 9.6E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 PRINTS PR00315 GTP-binding elongation factor signature 78 88 9.6E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 PRINTS PR00315 GTP-binding elongation factor signature 14 27 9.6E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_14365 7a0103b732d75b38a212502da3f7cc53 396 PRINTS PR00315 GTP-binding elongation factor signature 131 140 9.6E-24 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_03005 987d2fc9681902c63c786b553febdabf 729 SMART SM00926 37 91 2.4E-6 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_03005 987d2fc9681902c63c786b553febdabf 729 Gene3D G3DSA:2.40.40.20 586 729 9.1E-52 T 13-10-2018 THITH_03005 987d2fc9681902c63c786b553febdabf 729 Pfam PF01568 Molydopterin dinucleotide binding domain 600 713 7.0E-15 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 THITH_03005 987d2fc9681902c63c786b553febdabf 729 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 39 85 6.6E-6 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_03005 987d2fc9681902c63c786b553febdabf 729 Pfam PF00384 Molybdopterin oxidoreductase 94 510 3.2E-52 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_03005 987d2fc9681902c63c786b553febdabf 729 Gene3D G3DSA:3.40.228.10 169 578 2.4E-138 T 13-10-2018 THITH_03005 987d2fc9681902c63c786b553febdabf 729 SUPERFAMILY SSF53706 36 587 3.8E-137 T 13-10-2018 THITH_03005 987d2fc9681902c63c786b553febdabf 729 Gene3D G3DSA:3.40.50.740 106 514 2.4E-138 T 13-10-2018 THITH_03005 987d2fc9681902c63c786b553febdabf 729 Gene3D G3DSA:2.20.25.90 33 96 2.7E-18 T 13-10-2018 THITH_03005 987d2fc9681902c63c786b553febdabf 729 SUPERFAMILY SSF50692 563 723 1.49E-29 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily THITH_03005 987d2fc9681902c63c786b553febdabf 729 Gene3D G3DSA:3.30.2070.10 467 550 2.4E-138 T 13-10-2018 THITH_07020 df87a94b6f587b5871976e545e7abe13 798 Gene3D G3DSA:1.10.540.10 80 193 4.6E-104 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 THITH_07020 df87a94b6f587b5871976e545e7abe13 798 SUPERFAMILY SSF47203 318 465 1.32E-26 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 THITH_07020 df87a94b6f587b5871976e545e7abe13 798 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 99 191 1.8E-17 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 THITH_07020 df87a94b6f587b5871976e545e7abe13 798 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 195 285 1.2E-9 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 THITH_07020 df87a94b6f587b5871976e545e7abe13 798 SUPERFAMILY SSF56645 79 313 8.38E-48 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 THITH_07020 df87a94b6f587b5871976e545e7abe13 798 Gene3D G3DSA:1.20.140.10 318 465 4.6E-104 T 13-10-2018 THITH_07020 df87a94b6f587b5871976e545e7abe13 798 Pfam PF09317 Domain of unknown function (DUF1974) 472 754 1.1E-97 T 13-10-2018 IPR015396 Acyl-CoA dehydrogenase, C-termina, bacterial type GO:0003995|GO:0033539|GO:0055114 KEGG: 00071+1.3.8.8+1.3.8.7|KEGG: 00280+1.3.8.7|KEGG: 00410+1.3.8.7|KEGG: 00640+1.3.8.7|MetaCyc: PWY-7094|MetaCyc: PWY-7654 THITH_07020 df87a94b6f587b5871976e545e7abe13 798 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 318 465 6.4E-16 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THITH_07020 df87a94b6f587b5871976e545e7abe13 798 Gene3D G3DSA:2.40.110.10 194 317 4.6E-104 T 13-10-2018 THITH_11460 ab85dbde3192caa00916384d76161317 385 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 270 371 5.6E-12 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_11460 ab85dbde3192caa00916384d76161317 385 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 51 155 2.1E-10 T 13-10-2018 IPR000014 PAS domain THITH_11460 ab85dbde3192caa00916384d76161317 385 SUPERFAMILY SSF55785 51 155 2.09E-14 T 13-10-2018 IPR035965 PAS domain superfamily THITH_11460 ab85dbde3192caa00916384d76161317 385 SUPERFAMILY SSF47384 153 220 4.32E-5 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_11460 ab85dbde3192caa00916384d76161317 385 Pfam PF00989 PAS fold 50 155 2.2E-7 T 13-10-2018 IPR013767 PAS fold GO:0006355 THITH_11460 ab85dbde3192caa00916384d76161317 385 SMART SM00387 269 373 2.2E-16 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_11460 ab85dbde3192caa00916384d76161317 385 SMART SM00091 47 113 1.9E-4 T 13-10-2018 IPR000014 PAS domain THITH_11460 ab85dbde3192caa00916384d76161317 385 Gene3D G3DSA:1.10.287.130 170 224 3.7E-26 T 13-10-2018 THITH_11460 ab85dbde3192caa00916384d76161317 385 Gene3D G3DSA:3.30.565.10 225 370 3.7E-26 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_11460 ab85dbde3192caa00916384d76161317 385 SUPERFAMILY SSF55874 228 371 2.88E-24 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_11460 ab85dbde3192caa00916384d76161317 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 318 1.1E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_11460 ab85dbde3192caa00916384d76161317 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 333 351 1.1E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_11460 ab85dbde3192caa00916384d76161317 385 PRINTS PR00344 Bacterial sensor protein C-terminal signature 357 370 1.1E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_11460 ab85dbde3192caa00916384d76161317 385 Gene3D G3DSA:3.30.450.20 44 156 1.6E-15 T 13-10-2018 THITH_07535 e3dc58cbd96daa8d42e4fe1187163bcd 505 Gene3D G3DSA:3.30.420.40 4 254 2.7E-98 T 13-10-2018 THITH_07535 e3dc58cbd96daa8d42e4fe1187163bcd 505 SUPERFAMILY SSF53067 256 498 4.53E-83 T 13-10-2018 THITH_07535 e3dc58cbd96daa8d42e4fe1187163bcd 505 SUPERFAMILY SSF53067 5 256 8.64E-86 T 13-10-2018 THITH_07535 e3dc58cbd96daa8d42e4fe1187163bcd 505 Gene3D G3DSA:3.30.420.40 255 505 8.9E-90 T 13-10-2018 THITH_07535 e3dc58cbd96daa8d42e4fe1187163bcd 505 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 5 498 8.5E-200 T 13-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 THITH_07535 e3dc58cbd96daa8d42e4fe1187163bcd 505 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 452 2.0E-59 T 13-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 THITH_07535 e3dc58cbd96daa8d42e4fe1187163bcd 505 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 364 384 - T 13-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 THITH_07535 e3dc58cbd96daa8d42e4fe1187163bcd 505 PIRSF PIRSF000538 3 504 4.3E-174 T 13-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 THITH_07535 e3dc58cbd96daa8d42e4fe1187163bcd 505 Hamap MF_00186 Glycerol kinase [glpK]. 3 499 54.119 T 13-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 THITH_07535 e3dc58cbd96daa8d42e4fe1187163bcd 505 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 253 3.7E-73 T 13-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 THITH_09360 6fdfe919b80be8ffaae2103bee8d9c6e 59 Gene3D G3DSA:3.30.70.1680 2 58 1.1E-16 T 13-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 THITH_09360 6fdfe919b80be8ffaae2103bee8d9c6e 59 SUPERFAMILY SSF117130 3 50 9.81E-14 T 13-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 THITH_09360 6fdfe919b80be8ffaae2103bee8d9c6e 59 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 46 2.0E-7 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 THITH_09360 6fdfe919b80be8ffaae2103bee8d9c6e 59 Pfam PF02599 Global regulator protein family 4 49 9.8E-18 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 THITH_09360 6fdfe919b80be8ffaae2103bee8d9c6e 59 Hamap MF_00167 Translational regulator CsrA [csrA]. 1 57 13.559 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 THITH_13585 673a3b7be4728f72272b4ade762f7b64 667 ProSitePatterns PS01303 BCCT family of transporters signature. 325 334 - T 13-10-2018 IPR018093 BCCT transporter, conserved site THITH_13585 673a3b7be4728f72272b4ade762f7b64 667 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 63 506 4.1E-165 T 13-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 THITH_13585 673a3b7be4728f72272b4ade762f7b64 667 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 25 506 1.8E-199 T 13-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 THITH_08630 f41ffff94fb2e617589b67b50bc5426b 122 SUPERFAMILY SSF75169 9 116 4.12E-13 T 13-10-2018 IPR027396 DsrEFH-like THITH_08630 f41ffff94fb2e617589b67b50bc5426b 122 Gene3D G3DSA:3.40.1260.10 1 120 9.8E-28 T 13-10-2018 IPR027396 DsrEFH-like THITH_08630 f41ffff94fb2e617589b67b50bc5426b 122 Pfam PF02635 DsrE/DsrF-like family 8 92 1.7E-7 T 13-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THITH_11495 c2a672b9de8b69ddf74209a6635427d2 317 SUPERFAMILY SSF116734 1 69 1.8E-14 T 13-10-2018 THITH_11495 c2a672b9de8b69ddf74209a6635427d2 317 Gene3D G3DSA:3.90.220.20 88 234 2.3E-55 T 13-10-2018 THITH_11495 c2a672b9de8b69ddf74209a6635427d2 317 Gene3D G3DSA:1.10.287.1120 16 281 2.3E-55 T 13-10-2018 THITH_11495 c2a672b9de8b69ddf74209a6635427d2 317 Pfam PF01420 Type I restriction modification DNA specificity domain 148 248 1.3E-5 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THITH_11495 c2a672b9de8b69ddf74209a6635427d2 317 SUPERFAMILY SSF116734 68 289 2.13E-40 T 13-10-2018 THITH_11495 c2a672b9de8b69ddf74209a6635427d2 317 Gene3D G3DSA:3.90.220.20 1 285 2.3E-55 T 13-10-2018 THITH_11630 449147bf1c1df170d0da36e8c2b88b84 161 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 12 157 31.634 T 13-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THITH_11630 449147bf1c1df170d0da36e8c2b88b84 161 Gene3D G3DSA:3.40.50.960 4 158 9.9E-60 T 13-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THITH_11630 449147bf1c1df170d0da36e8c2b88b84 161 SUPERFAMILY SSF52121 11 158 1.01E-59 T 13-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THITH_11630 449147bf1c1df170d0da36e8c2b88b84 161 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 154 1.4E-56 T 13-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THITH_11630 449147bf1c1df170d0da36e8c2b88b84 161 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 18 153 2.6E-55 T 13-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 SUPERFAMILY SSF52540 324 598 2.33E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 SUPERFAMILY SSF88697 18 210 9.19E-48 T 13-10-2018 IPR015947 PUA-like superfamily THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 Gene3D G3DSA:3.40.50.300 323 499 6.7E-60 T 13-10-2018 THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 683 702 9.2E-56 T 13-10-2018 THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 736 754 9.2E-56 T 13-10-2018 THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 365 384 9.2E-56 T 13-10-2018 THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 605 621 9.2E-56 T 13-10-2018 THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 713 732 9.2E-56 T 13-10-2018 THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 SMART SM00464 18 211 3.3E-74 T 13-10-2018 IPR003111 Lon, substrate-binding domain THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 361 498 3.3E-15 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 Hamap MF_01973 Lon protease [lon]. 19 782 71.566 T 13-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 Gene3D G3DSA:1.10.8.60 500 594 3.7E-32 T 13-10-2018 THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 19 206 2.1E-40 T 13-10-2018 IPR003111 Lon, substrate-binding domain THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 Gene3D G3DSA:1.20.58.1480 130 253 3.3E-43 T 13-10-2018 THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 PIRSF PIRSF001174 2 785 0.0 T 13-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 580 782 7.2E-97 T 13-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 TIGRFAM TIGR00763 lon: endopeptidase La 21 780 5.7E-298 T 13-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 SMART SM00382 357 501 2.5E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 Gene3D G3DSA:2.30.130.40 14 125 1.9E-32 T 13-10-2018 THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 SUPERFAMILY SSF54211 605 780 1.25E-58 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_13420 b20e82a17e6b5284dc886c623bd2f7ed 815 Gene3D G3DSA:3.30.230.10 596 782 1.3E-80 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THITH_04250 32f8c0a7095356c34f8328a9684d42fd 236 SUPERFAMILY SSF53335 19 234 2.13E-35 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_04250 32f8c0a7095356c34f8328a9684d42fd 236 PIRSF PIRSF006325 6 236 2.9E-55 T 13-10-2018 IPR005271 Carboxy-S-adenosyl-L-methionine synthase GO:0002098 THITH_04250 32f8c0a7095356c34f8328a9684d42fd 236 Pfam PF13649 Methyltransferase domain 59 152 2.3E-14 T 13-10-2018 THITH_04250 32f8c0a7095356c34f8328a9684d42fd 236 Gene3D G3DSA:3.40.50.150 15 236 1.2E-52 T 13-10-2018 THITH_05115 ce2219229e1575ae681b3b3e3b17dbcf 384 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 7 372 7.9E-112 T 13-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 THITH_05115 ce2219229e1575ae681b3b3e3b17dbcf 384 SUPERFAMILY SSF53597 145 376 1.52E-56 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 THITH_05115 ce2219229e1575ae681b3b3e3b17dbcf 384 Pfam PF01872 RibD C-terminal domain 147 350 4.6E-48 T 13-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 THITH_05115 ce2219229e1575ae681b3b3e3b17dbcf 384 Gene3D G3DSA:3.40.140.10 1 140 2.7E-46 T 13-10-2018 THITH_05115 ce2219229e1575ae681b3b3e3b17dbcf 384 SUPERFAMILY SSF53927 3 144 9.25E-49 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 THITH_05115 ce2219229e1575ae681b3b3e3b17dbcf 384 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 100 5.5E-19 T 13-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain THITH_05115 ce2219229e1575ae681b3b3e3b17dbcf 384 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 146 377 6.8E-52 T 13-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 THITH_05115 ce2219229e1575ae681b3b3e3b17dbcf 384 PIRSF PIRSF006769 1 380 3.7E-126 T 13-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 THITH_05115 ce2219229e1575ae681b3b3e3b17dbcf 384 Gene3D G3DSA:3.40.430.10 141 380 6.3E-66 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 THITH_05115 ce2219229e1575ae681b3b3e3b17dbcf 384 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 88 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 THITH_07125 477a4f079b559bcbe4647ff2c2bd941d 493 SUPERFAMILY SSF56672 21 244 2.89E-31 T 13-10-2018 THITH_07125 477a4f079b559bcbe4647ff2c2bd941d 493 Gene3D G3DSA:2.30.40.20 55 88 1.5E-9 T 13-10-2018 THITH_07125 477a4f079b559bcbe4647ff2c2bd941d 493 Pfam PF00817 impB/mucB/samB family 44 168 3.8E-8 T 13-10-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 THITH_07125 477a4f079b559bcbe4647ff2c2bd941d 493 Gene3D G3DSA:1.10.150.20 188 235 1.5E-9 T 13-10-2018 THITH_07125 477a4f079b559bcbe4647ff2c2bd941d 493 Gene3D G3DSA:3.30.70.270 89 187 1.5E-9 T 13-10-2018 THITH_01440 6c9fc73884066575872a2e5b0188569d 419 TIGRFAM TIGR00767 rho: transcription termination factor Rho 2 417 5.6E-215 T 13-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 THITH_01440 6c9fc73884066575872a2e5b0188569d 419 Gene3D G3DSA:3.40.50.300 130 417 8.5E-131 T 13-10-2018 THITH_01440 6c9fc73884066575872a2e5b0188569d 419 SMART SM00959 5 47 5.2E-17 T 13-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 THITH_01440 6c9fc73884066575872a2e5b0188569d 419 Gene3D G3DSA:2.40.50.140 48 123 4.2E-34 T 13-10-2018 THITH_01440 6c9fc73884066575872a2e5b0188569d 419 SUPERFAMILY SSF68912 1 46 1.1E-11 T 13-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily THITH_01440 6c9fc73884066575872a2e5b0188569d 419 Pfam PF07497 Rho termination factor, RNA-binding domain 52 125 1.9E-31 T 13-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 THITH_01440 6c9fc73884066575872a2e5b0188569d 419 SUPERFAMILY SSF52540 90 371 4.43E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01440 6c9fc73884066575872a2e5b0188569d 419 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 419 248.547 T 13-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 THITH_01440 6c9fc73884066575872a2e5b0188569d 419 Pfam PF07498 Rho termination factor, N-terminal domain 5 47 1.6E-15 T 13-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 THITH_01440 6c9fc73884066575872a2e5b0188569d 419 SMART SM00382 170 356 3.2E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_01440 6c9fc73884066575872a2e5b0188569d 419 SMART SM00357 52 118 2.9E-19 T 13-10-2018 IPR011129 Cold shock domain GO:0003676 THITH_01440 6c9fc73884066575872a2e5b0188569d 419 SUPERFAMILY SSF50249 49 125 9.42E-29 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_01440 6c9fc73884066575872a2e5b0188569d 419 Gene3D G3DSA:1.10.720.10 1 47 2.4E-19 T 13-10-2018 THITH_01440 6c9fc73884066575872a2e5b0188569d 419 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 363 1.3E-23 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_00395 772e23d43972799c9bedb2770aea4239 107 Gene3D G3DSA:2.30.30.110 9 107 3.8E-18 T 13-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THITH_00395 772e23d43972799c9bedb2770aea4239 107 SUPERFAMILY SSF50118 1 106 6.05E-25 T 13-10-2018 THITH_00395 772e23d43972799c9bedb2770aea4239 107 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 2 103 2.1E-18 T 13-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THITH_11620 2edb73ef058bd7e1686083debb459326 328 SUPERFAMILY SSF56042 145 309 6.43E-32 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THITH_11620 2edb73ef058bd7e1686083debb459326 328 Gene3D G3DSA:3.90.650.10 148 325 7.4E-49 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THITH_11620 2edb73ef058bd7e1686083debb459326 328 Gene3D G3DSA:3.30.1330.10 5 146 9.5E-45 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THITH_11620 2edb73ef058bd7e1686083debb459326 328 SUPERFAMILY SSF55326 7 140 4.97E-32 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THITH_11620 2edb73ef058bd7e1686083debb459326 328 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 6 325 26.631 T 13-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 THITH_11620 2edb73ef058bd7e1686083debb459326 328 Pfam PF02769 AIR synthase related protein, C-terminal domain 152 307 5.7E-8 T 13-10-2018 IPR010918 PurM-like, C-terminal domain THITH_11620 2edb73ef058bd7e1686083debb459326 328 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 8 325 1.3E-90 T 13-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 THITH_11620 2edb73ef058bd7e1686083debb459326 328 Pfam PF00586 AIR synthase related protein, N-terminal domain 31 140 1.1E-23 T 13-10-2018 IPR016188 PurM-like, N-terminal domain THITH_11620 2edb73ef058bd7e1686083debb459326 328 PIRSF PIRSF005303 1 325 2.1E-78 T 13-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 THITH_10730 98dcb1314957065dba20424542462001 501 Gene3D G3DSA:3.60.20.10 2 413 2.0E-146 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_10730 98dcb1314957065dba20424542462001 501 Gene3D G3DSA:3.40.50.2020 278 442 2.0E-146 T 13-10-2018 THITH_10730 98dcb1314957065dba20424542462001 501 SUPERFAMILY SSF56235 2 258 4.37E-69 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_10730 98dcb1314957065dba20424542462001 501 Pfam PF13522 Glutamine amidotransferase domain 66 209 1.8E-16 T 13-10-2018 THITH_10730 98dcb1314957065dba20424542462001 501 Pfam PF00156 Phosphoribosyl transferase domain 289 394 4.7E-7 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 THITH_10730 98dcb1314957065dba20424542462001 501 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 465 1.9E-154 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 THITH_10730 98dcb1314957065dba20424542462001 501 PIRSF PIRSF000485 1 474 1.3E-156 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 THITH_10730 98dcb1314957065dba20424542462001 501 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 465 44.065 T 13-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 THITH_10730 98dcb1314957065dba20424542462001 501 SUPERFAMILY SSF53271 251 472 4.2E-69 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like THITH_01265 7ded7795acfb0936719445e2b0fe351f 400 SUPERFAMILY SSF161111 17 219 2.75E-56 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily THITH_01265 7ded7795acfb0936719445e2b0fe351f 400 Gene3D G3DSA:3.30.70.1350 219 301 7.4E-23 T 13-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 THITH_01265 7ded7795acfb0936719445e2b0fe351f 400 Pfam PF16916 Dimerisation domain of Zinc Transporter 223 300 5.8E-25 T 13-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain THITH_01265 7ded7795acfb0936719445e2b0fe351f 400 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 23 301 3.9E-76 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THITH_01265 7ded7795acfb0936719445e2b0fe351f 400 Gene3D G3DSA:1.20.1510.10 20 218 1.2E-64 T 13-10-2018 IPR027469 Cation efflux transmembrane domain superfamily THITH_01265 7ded7795acfb0936719445e2b0fe351f 400 SUPERFAMILY SSF160240 222 302 2.88E-21 T 13-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 THITH_01265 7ded7795acfb0936719445e2b0fe351f 400 Pfam PF01545 Cation efflux family 25 217 1.6E-48 T 13-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 THITH_13840 1d5a2558e0144d1dc2b6858851cf748e 205 SMART SM00877 137 204 1.8E-13 T 13-10-2018 IPR000249 Microcompartment protein, bacteria THITH_13840 1d5a2558e0144d1dc2b6858851cf748e 205 Gene3D G3DSA:3.30.70.1810 1 102 2.2E-38 T 13-10-2018 THITH_13840 1d5a2558e0144d1dc2b6858851cf748e 205 Gene3D G3DSA:3.30.70.1810 103 203 4.2E-36 T 13-10-2018 THITH_13840 1d5a2558e0144d1dc2b6858851cf748e 205 SUPERFAMILY SSF143414 137 200 1.09E-8 T 13-10-2018 IPR037233 CcmK-like superfamily THITH_00140 6810c4cda1ef8c0e2a8e52ddcf795c4c 654 Gene3D G3DSA:3.30.1370.120 260 337 7.3E-16 T 13-10-2018 IPR038591 NolW-like superfamily THITH_00140 6810c4cda1ef8c0e2a8e52ddcf795c4c 654 Gene3D G3DSA:3.30.1370.120 187 255 1.6E-16 T 13-10-2018 IPR038591 NolW-like superfamily THITH_00140 6810c4cda1ef8c0e2a8e52ddcf795c4c 654 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 29 596 1.5E-161 T 13-10-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 THITH_00140 6810c4cda1ef8c0e2a8e52ddcf795c4c 654 Gene3D G3DSA:3.30.1370.120 19 183 1.2E-54 T 13-10-2018 IPR038591 NolW-like superfamily THITH_00140 6810c4cda1ef8c0e2a8e52ddcf795c4c 654 PRINTS PR00811 Bacterial general secretion pathway protein D signature 422 446 4.1E-30 T 13-10-2018 IPR001775 GspD/PilQ family THITH_00140 6810c4cda1ef8c0e2a8e52ddcf795c4c 654 PRINTS PR00811 Bacterial general secretion pathway protein D signature 457 467 4.1E-30 T 13-10-2018 IPR001775 GspD/PilQ family THITH_00140 6810c4cda1ef8c0e2a8e52ddcf795c4c 654 PRINTS PR00811 Bacterial general secretion pathway protein D signature 574 588 4.1E-30 T 13-10-2018 IPR001775 GspD/PilQ family THITH_00140 6810c4cda1ef8c0e2a8e52ddcf795c4c 654 PRINTS PR00811 Bacterial general secretion pathway protein D signature 551 569 4.1E-30 T 13-10-2018 IPR001775 GspD/PilQ family THITH_00140 6810c4cda1ef8c0e2a8e52ddcf795c4c 654 PRINTS PR00811 Bacterial general secretion pathway protein D signature 339 349 4.1E-30 T 13-10-2018 IPR001775 GspD/PilQ family THITH_00140 6810c4cda1ef8c0e2a8e52ddcf795c4c 654 Pfam PF00263 Bacterial type II and III secretion system protein 426 587 3.1E-49 T 13-10-2018 IPR004846 Type II/III secretion system GO:0009306 THITH_00140 6810c4cda1ef8c0e2a8e52ddcf795c4c 654 Pfam PF03958 Bacterial type II/III secretion system short domain 262 339 9.3E-15 T 13-10-2018 IPR005644 NolW-like THITH_00140 6810c4cda1ef8c0e2a8e52ddcf795c4c 654 Pfam PF03958 Bacterial type II/III secretion system short domain 125 183 6.9E-11 T 13-10-2018 IPR005644 NolW-like THITH_00140 6810c4cda1ef8c0e2a8e52ddcf795c4c 654 Pfam PF03958 Bacterial type II/III secretion system short domain 189 258 3.3E-14 T 13-10-2018 IPR005644 NolW-like THITH_00060 ea0bfc0a05276a005c67ebafd8b7c00c 346 SUPERFAMILY SSF52343 201 337 5.11E-33 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain THITH_00060 ea0bfc0a05276a005c67ebafd8b7c00c 346 SUPERFAMILY SSF54292 1 90 3.01E-26 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 THITH_00060 ea0bfc0a05276a005c67ebafd8b7c00c 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 192 201 1.8E-23 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THITH_00060 ea0bfc0a05276a005c67ebafd8b7c00c 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 148 155 1.8E-23 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THITH_00060 ea0bfc0a05276a005c67ebafd8b7c00c 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 208 227 1.8E-23 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THITH_00060 ea0bfc0a05276a005c67ebafd8b7c00c 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 303 311 1.8E-23 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THITH_00060 ea0bfc0a05276a005c67ebafd8b7c00c 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 132 144 1.8E-23 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THITH_00060 ea0bfc0a05276a005c67ebafd8b7c00c 346 PRINTS PR00410 Phenol hydroxylase reductase family signature 233 242 1.8E-23 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THITH_00060 ea0bfc0a05276a005c67ebafd8b7c00c 346 Gene3D G3DSA:3.40.50.80 200 336 4.5E-26 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain THITH_00060 ea0bfc0a05276a005c67ebafd8b7c00c 346 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 81 9.1E-14 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THITH_00060 ea0bfc0a05276a005c67ebafd8b7c00c 346 Pfam PF00970 Oxidoreductase FAD-binding domain 105 197 1.6E-16 T 13-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 THITH_00060 ea0bfc0a05276a005c67ebafd8b7c00c 346 SUPERFAMILY SSF63380 102 198 7.35E-25 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel THITH_00060 ea0bfc0a05276a005c67ebafd8b7c00c 346 Gene3D G3DSA:2.40.30.10 101 199 2.5E-25 T 13-10-2018 THITH_00060 ea0bfc0a05276a005c67ebafd8b7c00c 346 Pfam PF00175 Oxidoreductase NAD-binding domain 209 316 2.7E-14 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THITH_00060 ea0bfc0a05276a005c67ebafd8b7c00c 346 Gene3D G3DSA:3.10.20.30 1 98 3.4E-25 T 13-10-2018 IPR012675 Beta-grasp domain superfamily THITH_00060 ea0bfc0a05276a005c67ebafd8b7c00c 346 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 37 45 - T 13-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 THITH_05470 60847842bb3640d915ff9d9de0eafbb2 639 Pfam PF16448 LapD/MoxY periplasmic domain 25 144 1.0E-39 T 13-10-2018 IPR032244 LapD/MoxY, periplasmic domain THITH_05470 60847842bb3640d915ff9d9de0eafbb2 639 Pfam PF00990 Diguanylate cyclase, GGDEF domain 234 386 8.7E-15 T 13-10-2018 IPR000160 GGDEF domain THITH_05470 60847842bb3640d915ff9d9de0eafbb2 639 SUPERFAMILY SSF141868 412 632 1.26E-42 T 13-10-2018 IPR035919 EAL domain superfamily THITH_05470 60847842bb3640d915ff9d9de0eafbb2 639 SMART SM00267 223 392 4.7E-7 T 13-10-2018 IPR000160 GGDEF domain THITH_05470 60847842bb3640d915ff9d9de0eafbb2 639 SMART SM00052 405 636 6.3E-15 T 13-10-2018 IPR001633 EAL domain THITH_05470 60847842bb3640d915ff9d9de0eafbb2 639 Gene3D G3DSA:3.20.20.450 403 635 1.7E-45 T 13-10-2018 IPR035919 EAL domain superfamily THITH_05470 60847842bb3640d915ff9d9de0eafbb2 639 SUPERFAMILY SSF55073 240 391 2.75E-13 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_05470 60847842bb3640d915ff9d9de0eafbb2 639 Gene3D G3DSA:3.30.70.270 217 392 1.3E-20 T 13-10-2018 THITH_05470 60847842bb3640d915ff9d9de0eafbb2 639 Gene3D G3DSA:3.30.1040.50 100 148 1.3E-15 T 13-10-2018 THITH_05470 60847842bb3640d915ff9d9de0eafbb2 639 Pfam PF00563 EAL domain 412 632 5.9E-41 T 13-10-2018 IPR001633 EAL domain THITH_01345 400578c4930cd0b9d5999586fa87020c 402 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 96 112 3.4E-8 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THITH_01345 400578c4930cd0b9d5999586fa87020c 402 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 250 272 3.4E-8 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THITH_01345 400578c4930cd0b9d5999586fa87020c 402 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 225 237 3.4E-8 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THITH_01345 400578c4930cd0b9d5999586fa87020c 402 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 129 146 3.4E-8 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THITH_01345 400578c4930cd0b9d5999586fa87020c 402 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 167 183 3.4E-8 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THITH_01345 400578c4930cd0b9d5999586fa87020c 402 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 3.4E-8 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THITH_01345 400578c4930cd0b9d5999586fa87020c 402 PIRSF PIRSF036483 1 401 1.4E-130 T 13-10-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00010+2.7.1.90|KEGG: 00030+2.7.1.90|KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 THITH_01345 400578c4930cd0b9d5999586fa87020c 402 Pfam PF00365 Phosphofructokinase 3 319 7.3E-48 T 13-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THITH_01345 400578c4930cd0b9d5999586fa87020c 402 Hamap MF_01978 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 394 39.421 T 13-10-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00010+2.7.1.90|KEGG: 00030+2.7.1.90|KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 THITH_01345 400578c4930cd0b9d5999586fa87020c 402 Gene3D G3DSA:3.40.50.460 134 381 2.6E-123 T 13-10-2018 THITH_01345 400578c4930cd0b9d5999586fa87020c 402 Gene3D G3DSA:3.40.50.450 4 382 2.6E-123 T 13-10-2018 THITH_01345 400578c4930cd0b9d5999586fa87020c 402 SUPERFAMILY SSF53784 2 388 2.09E-89 T 13-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THITH_06020 4d668a67a2afb2769d6fab8ad98bfdcd 390 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 37 381 2.6E-86 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THITH_06020 4d668a67a2afb2769d6fab8ad98bfdcd 390 Gene3D G3DSA:3.90.1150.10 281 383 3.7E-13 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_06020 4d668a67a2afb2769d6fab8ad98bfdcd 390 TIGRFAM TIGR04181 NHT_00031: aminotransferase, LLPSF_NHT_00031 family 24 381 4.7E-162 T 13-10-2018 IPR026385 Aminotransferase, LLPSF_NHT_00031 family THITH_06020 4d668a67a2afb2769d6fab8ad98bfdcd 390 Gene3D G3DSA:3.40.640.10 12 280 2.3E-91 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_06020 4d668a67a2afb2769d6fab8ad98bfdcd 390 SUPERFAMILY SSF53383 23 382 5.35E-94 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_06020 4d668a67a2afb2769d6fab8ad98bfdcd 390 PIRSF PIRSF000390 21 384 9.7E-91 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THITH_04000 99264256578dd84aae8ed0dd858ca177 83 Gene3D G3DSA:2.60.120.10 2 83 9.1E-17 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_04000 99264256578dd84aae8ed0dd858ca177 83 Pfam PF12973 ChrR Cupin-like domain 7 76 2.8E-9 T 13-10-2018 IPR025979 ChrR-like cupin domain THITH_04000 99264256578dd84aae8ed0dd858ca177 83 SUPERFAMILY SSF51182 7 76 3.34E-14 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily THITH_12905 4bbce813379c880dc16d45993fcf1237 940 Pfam PF11987 Translation-initiation factor 2 725 830 7.2E-36 T 13-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 THITH_12905 4bbce813379c880dc16d45993fcf1237 940 ProSitePatterns PS01176 Initiation factor 2 signature. 891 913 - T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 THITH_12905 4bbce813379c880dc16d45993fcf1237 940 Pfam PF00009 Elongation factor Tu GTP binding domain 445 599 1.0E-35 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_12905 4bbce813379c880dc16d45993fcf1237 940 Gene3D G3DSA:3.40.50.300 438 611 8.9E-71 T 13-10-2018 THITH_12905 4bbce813379c880dc16d45993fcf1237 940 SUPERFAMILY SSF46955 3 51 1.03E-8 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily THITH_12905 4bbce813379c880dc16d45993fcf1237 940 Gene3D G3DSA:3.40.50.10050 734 841 3.2E-35 T 13-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily THITH_12905 4bbce813379c880dc16d45993fcf1237 940 Pfam PF08364 Bacterial translation initiation factor IF-2 associated region 62 99 1.0E-11 T 13-10-2018 IPR013575 Initiation factor 2 associated domain, bacterial THITH_12905 4bbce813379c880dc16d45993fcf1237 940 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 359 939 8.9E-262 T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 THITH_12905 4bbce813379c880dc16d45993fcf1237 940 SUPERFAMILY SSF50447 842 938 4.71E-33 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THITH_12905 4bbce813379c880dc16d45993fcf1237 940 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 938 17.354 T 13-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 THITH_12905 4bbce813379c880dc16d45993fcf1237 940 Gene3D G3DSA:2.40.30.10 842 939 1.3E-32 T 13-10-2018 THITH_12905 4bbce813379c880dc16d45993fcf1237 940 SUPERFAMILY SSF50447 613 695 1.86E-24 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THITH_12905 4bbce813379c880dc16d45993fcf1237 940 Gene3D G3DSA:2.40.30.10 612 730 7.8E-42 T 13-10-2018 THITH_12905 4bbce813379c880dc16d45993fcf1237 940 Gene3D G3DSA:3.30.56.50 2 51 9.9E-8 T 13-10-2018 THITH_12905 4bbce813379c880dc16d45993fcf1237 940 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 443 598 7.3E-32 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THITH_12905 4bbce813379c880dc16d45993fcf1237 940 SUPERFAMILY SSF52156 719 847 1.83E-35 T 13-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily THITH_12905 4bbce813379c880dc16d45993fcf1237 940 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 364 415 3.8E-16 T 13-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal THITH_12905 4bbce813379c880dc16d45993fcf1237 940 SUPERFAMILY SSF52540 439 630 2.32E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_12800 2f2f1f3a12f032b1a03ca339d5e25ca1 480 Pfam PF02601 Exonuclease VII, large subunit 123 460 7.6E-94 T 13-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 THITH_12800 2f2f1f3a12f032b1a03ca339d5e25ca1 480 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 9 353 3.9E-126 T 13-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 THITH_12800 2f2f1f3a12f032b1a03ca339d5e25ca1 480 Pfam PF13742 OB-fold nucleic acid binding domain 8 99 1.3E-26 T 13-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 THITH_12800 2f2f1f3a12f032b1a03ca339d5e25ca1 480 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 5 464 27.907 T 13-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 THITH_13520 ca2c6dc3c97c5106793ff3eba02067ce 185 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 11 170 1.7E-41 T 13-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 THITH_13520 ca2c6dc3c97c5106793ff3eba02067ce 185 Gene3D G3DSA:3.40.50.300 11 170 7.3E-57 T 13-10-2018 THITH_13520 ca2c6dc3c97c5106793ff3eba02067ce 185 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 11 146 1.9E-51 T 13-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 THITH_13520 ca2c6dc3c97c5106793ff3eba02067ce 185 SUPERFAMILY SSF52540 8 170 3.49E-23 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13520 ca2c6dc3c97c5106793ff3eba02067ce 185 Gene3D G3DSA:2.20.25.120 54 88 7.3E-57 T 13-10-2018 THITH_07060 111be9d39a141426de12d771b21f2955 1151 SMART SM00481 5 72 5.7E-22 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal THITH_07060 111be9d39a141426de12d771b21f2955 1151 Pfam PF14579 Helix-hairpin-helix motif 792 881 2.1E-26 T 13-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_07060 111be9d39a141426de12d771b21f2955 1151 Gene3D G3DSA:2.40.50.140 980 1067 1.5E-5 T 13-10-2018 THITH_07060 111be9d39a141426de12d771b21f2955 1151 Gene3D G3DSA:1.10.10.1600 425 502 1.2E-30 T 13-10-2018 THITH_07060 111be9d39a141426de12d771b21f2955 1151 SUPERFAMILY SSF89550 4 260 1.18E-16 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 THITH_07060 111be9d39a141426de12d771b21f2955 1151 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 4 1021 0.0 T 13-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_07060 111be9d39a141426de12d771b21f2955 1151 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 289 718 2.1E-178 T 13-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_07060 111be9d39a141426de12d771b21f2955 1151 Pfam PF01336 OB-fold nucleic acid binding domain 986 1047 6.2E-7 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 THITH_07060 111be9d39a141426de12d771b21f2955 1151 Pfam PF02811 PHP domain 6 139 4.1E-34 T 13-10-2018 IPR004013 PHP domain GO:0003824 THITH_07060 111be9d39a141426de12d771b21f2955 1151 Gene3D G3DSA:1.10.150.870 766 870 2.9E-6 T 13-10-2018 THITH_07060 111be9d39a141426de12d771b21f2955 1151 Gene3D G3DSA:3.20.20.140 1 267 1.3E-82 T 13-10-2018 THITH_17505 adc79ff62fabe60b627552713c28df24 79 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 24.571 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor THITH_17505 adc79ff62fabe60b627552713c28df24 79 Pfam PF01809 Haemolytic domain 3 68 4.1E-30 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor THITH_17505 adc79ff62fabe60b627552713c28df24 79 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 7 78 1.0E-26 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor THITH_17505 adc79ff62fabe60b627552713c28df24 79 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 2.0E-16 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor THITH_17505 adc79ff62fabe60b627552713c28df24 79 SMART SM01234 1 68 1.3E-41 T 13-10-2018 IPR002696 Putative membrane protein insertion efficiency factor THITH_08315 d36e852d92e05529828c4849467bfa73 138 Pfam PF08780 Nucleotidyltransferase substrate binding protein like 10 133 2.7E-43 T 13-10-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 THITH_08315 d36e852d92e05529828c4849467bfa73 138 TIGRFAM TIGR01987 HI0074: nucleotidyltransferase substrate binding protein, HI0074 family 12 132 3.1E-27 T 13-10-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 THITH_08315 d36e852d92e05529828c4849467bfa73 138 Gene3D G3DSA:1.20.120.330 12 135 7.5E-34 T 13-10-2018 THITH_08315 d36e852d92e05529828c4849467bfa73 138 SUPERFAMILY SSF81593 5 132 1.14E-41 T 13-10-2018 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 SUPERFAMILY SSF51905 239 603 9.91E-58 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 580 686 1.3E-28 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 239 557 1.2E-56 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 272 282 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 Pfam PF09335 SNARE associated Golgi protein 68 184 2.1E-21 T 13-10-2018 IPR032816 SNARE associated Golgi protein THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 496 512 3.2E-28 T 13-10-2018 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 523 545 3.2E-28 T 13-10-2018 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 370 388 3.2E-28 T 13-10-2018 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 259 3.2E-28 T 13-10-2018 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 409 427 3.2E-28 T 13-10-2018 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 Gene3D G3DSA:3.50.50.60 240 561 9.0E-103 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 Gene3D G3DSA:3.30.390.30 579 699 2.0E-38 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 SUPERFAMILY SSF55424 576 691 1.51E-36 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 271 286 2.0E-59 T 13-10-2018 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 576 597 2.0E-59 T 13-10-2018 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 641 656 2.0E-59 T 13-10-2018 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 434 2.0E-59 T 13-10-2018 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 538 545 2.0E-59 T 13-10-2018 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 663 683 2.0E-59 T 13-10-2018 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 239 261 2.0E-59 T 13-10-2018 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 497 511 2.0E-59 T 13-10-2018 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 373 382 2.0E-59 T 13-10-2018 THITH_06190 4b20f6f08d3bdf386c50929ebd48fd15 714 Gene3D G3DSA:3.50.50.60 389 510 9.0E-103 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_14570 b09e102a1a83f602bf891bf77fb3180a 373 Gene3D G3DSA:2.30.42.10 272 372 4.1E-26 T 13-10-2018 THITH_14570 b09e102a1a83f602bf891bf77fb3180a 373 Pfam PF13365 Trypsin-like peptidase domain 104 238 5.5E-32 T 13-10-2018 THITH_14570 b09e102a1a83f602bf891bf77fb3180a 373 Pfam PF13180 PDZ domain 277 367 6.5E-14 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_14570 b09e102a1a83f602bf891bf77fb3180a 373 Gene3D G3DSA:2.40.10.120 52 271 4.3E-76 T 13-10-2018 THITH_14570 b09e102a1a83f602bf891bf77fb3180a 373 SUPERFAMILY SSF50494 52 274 4.05E-62 T 13-10-2018 IPR009003 Peptidase S1, PA clan THITH_14570 b09e102a1a83f602bf891bf77fb3180a 373 SMART SM00228 277 359 2.5E-13 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_14570 b09e102a1a83f602bf891bf77fb3180a 373 PRINTS PR00834 HtrA/DegQ protease family signature 174 198 5.9E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_14570 b09e102a1a83f602bf891bf77fb3180a 373 PRINTS PR00834 HtrA/DegQ protease family signature 113 125 5.9E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_14570 b09e102a1a83f602bf891bf77fb3180a 373 PRINTS PR00834 HtrA/DegQ protease family signature 231 248 5.9E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_14570 b09e102a1a83f602bf891bf77fb3180a 373 PRINTS PR00834 HtrA/DegQ protease family signature 134 154 5.9E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_14570 b09e102a1a83f602bf891bf77fb3180a 373 PRINTS PR00834 HtrA/DegQ protease family signature 209 226 5.9E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_14570 b09e102a1a83f602bf891bf77fb3180a 373 PRINTS PR00834 HtrA/DegQ protease family signature 317 329 5.9E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_14570 b09e102a1a83f602bf891bf77fb3180a 373 SUPERFAMILY SSF50156 235 360 2.5E-23 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 THITH_08450 34724427edea11f26dff46e1eae60d07 327 Gene3D G3DSA:1.25.40.20 237 325 1.1E-25 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily THITH_08450 34724427edea11f26dff46e1eae60d07 327 Pfam PF13857 Ankyrin repeats (many copies) 76 118 9.0E-8 T 13-10-2018 THITH_08450 34724427edea11f26dff46e1eae60d07 327 Pfam PF12796 Ankyrin repeats (3 copies) 170 261 4.0E-19 T 13-10-2018 IPR020683 Ankyrin repeat-containing domain THITH_08450 34724427edea11f26dff46e1eae60d07 327 Pfam PF13606 Ankyrin repeat 124 151 1.4E-5 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 THITH_08450 34724427edea11f26dff46e1eae60d07 327 SUPERFAMILY SSF48403 60 319 1.2E-69 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily THITH_08450 34724427edea11f26dff46e1eae60d07 327 SMART SM00248 297 327 1900.0 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 THITH_08450 34724427edea11f26dff46e1eae60d07 327 SMART SM00248 123 152 1.4E-6 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 THITH_08450 34724427edea11f26dff46e1eae60d07 327 SMART SM00248 231 260 0.0014 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 THITH_08450 34724427edea11f26dff46e1eae60d07 327 SMART SM00248 56 85 1000.0 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 THITH_08450 34724427edea11f26dff46e1eae60d07 327 SMART SM00248 89 118 9.4E-5 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 THITH_08450 34724427edea11f26dff46e1eae60d07 327 SMART SM00248 198 227 5.1E-6 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 THITH_08450 34724427edea11f26dff46e1eae60d07 327 SMART SM00248 264 293 1.9E-4 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 THITH_08450 34724427edea11f26dff46e1eae60d07 327 SMART SM00248 165 194 0.027 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 THITH_08450 34724427edea11f26dff46e1eae60d07 327 PRINTS PR01415 Ankyrin repeat signature 280 294 4.6E-8 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 THITH_08450 34724427edea11f26dff46e1eae60d07 327 PRINTS PR01415 Ankyrin repeat signature 199 214 4.6E-8 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 THITH_08450 34724427edea11f26dff46e1eae60d07 327 Pfam PF00023 Ankyrin repeat 264 291 0.0018 T 13-10-2018 IPR002110 Ankyrin repeat GO:0005515 THITH_08450 34724427edea11f26dff46e1eae60d07 327 Gene3D G3DSA:1.25.40.20 56 158 1.1E-27 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily THITH_08450 34724427edea11f26dff46e1eae60d07 327 Gene3D G3DSA:1.25.40.20 161 236 7.0E-24 T 13-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily THITH_02510 9e9a4063b9d669e00f54410fc853a5a1 425 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 4 424 4.2E-190 T 13-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 THITH_02510 9e9a4063b9d669e00f54410fc853a5a1 425 SUPERFAMILY SSF53383 2 425 7.58E-131 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_02510 9e9a4063b9d669e00f54410fc853a5a1 425 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 234 270 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THITH_02510 9e9a4063b9d669e00f54410fc853a5a1 425 Pfam PF00202 Aminotransferase class-III 32 394 2.3E-75 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THITH_02510 9e9a4063b9d669e00f54410fc853a5a1 425 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 3 425 104.65 T 13-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 THITH_02510 9e9a4063b9d669e00f54410fc853a5a1 425 Gene3D G3DSA:3.40.640.10 69 317 1.2E-177 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_02510 9e9a4063b9d669e00f54410fc853a5a1 425 Gene3D G3DSA:3.90.1150.10 8 417 1.2E-177 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_12425 5dbcfb67e2f7f98e598c2d187e30f3a3 292 SUPERFAMILY SSF53850 89 291 6.98E-37 T 13-10-2018 THITH_12425 5dbcfb67e2f7f98e598c2d187e30f3a3 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 19 30 4.9E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_12425 5dbcfb67e2f7f98e598c2d187e30f3a3 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 30 40 4.9E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_12425 5dbcfb67e2f7f98e598c2d187e30f3a3 292 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 4.9E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_12425 5dbcfb67e2f7f98e598c2d187e30f3a3 292 Gene3D G3DSA:3.40.190.10 90 291 1.1E-62 T 13-10-2018 THITH_12425 5dbcfb67e2f7f98e598c2d187e30f3a3 292 Gene3D G3DSA:1.10.10.10 1 89 2.0E-28 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_12425 5dbcfb67e2f7f98e598c2d187e30f3a3 292 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 63 4.4E-21 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_12425 5dbcfb67e2f7f98e598c2d187e30f3a3 292 Pfam PF03466 LysR substrate binding domain 89 291 4.6E-38 T 13-10-2018 IPR005119 LysR, substrate-binding THITH_12425 5dbcfb67e2f7f98e598c2d187e30f3a3 292 Gene3D G3DSA:3.40.190.10 163 268 1.1E-62 T 13-10-2018 THITH_12425 5dbcfb67e2f7f98e598c2d187e30f3a3 292 SUPERFAMILY SSF46785 1 111 1.04E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 Pfam PF00679 Elongation factor G C-terminus 600 686 2.8E-22 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 Hamap MF_00054_B Elongation factor G [fusA]. 7 692 96.992 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 SUPERFAMILY SSF54980 603 690 5.28E-22 T 13-10-2018 IPR035647 EF-G domain III/V-like THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 Pfam PF00009 Elongation factor Tu GTP binding domain 10 281 7.5E-67 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 SUPERFAMILY SSF52540 8 281 2.73E-105 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 Gene3D G3DSA:3.30.230.10 483 687 3.1E-73 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 SUPERFAMILY SSF54211 478 598 7.33E-37 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 TIGRFAM TIGR00484 EF-G: translation elongation factor G 5 688 1.1E-274 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 PRINTS PR00315 GTP-binding elongation factor signature 59 67 6.0E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 PRINTS PR00315 GTP-binding elongation factor signature 131 140 6.0E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 PRINTS PR00315 GTP-binding elongation factor signature 79 89 6.0E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 PRINTS PR00315 GTP-binding elongation factor signature 13 26 6.0E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 PRINTS PR00315 GTP-binding elongation factor signature 95 106 6.0E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 180 3.2E-36 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 52 67 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 Gene3D G3DSA:3.30.70.870 405 479 1.1E-27 T 13-10-2018 THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 Pfam PF03764 Elongation factor G, domain IV 478 595 1.0E-39 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 SUPERFAMILY SSF54980 403 480 2.37E-22 T 13-10-2018 IPR035647 EF-G domain III/V-like THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 SUPERFAMILY SSF50447 265 403 1.49E-34 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 Gene3D G3DSA:2.40.30.10 293 404 3.6E-41 T 13-10-2018 THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 Gene3D G3DSA:3.40.50.300 4 292 4.0E-109 T 13-10-2018 THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 SMART SM00838 600 688 1.6E-32 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 SMART SM00889 479 598 8.8E-56 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 Pfam PF14492 Elongation Factor G, domain II 403 476 4.7E-28 T 13-10-2018 THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 Pfam PF03144 Elongation factor Tu domain 2 323 390 1.1E-14 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THITH_13220 9bd387e3304e434e10db3bdeda9e8cde 698 Gene3D G3DSA:3.30.70.240 604 675 3.1E-73 T 13-10-2018 THITH_14150 cc3258825aea9531aeadf93608d1f7c9 461 Gene3D G3DSA:1.20.1250.20 1 388 9.7E-72 T 13-10-2018 THITH_14150 cc3258825aea9531aeadf93608d1f7c9 461 Pfam PF07690 Major Facilitator Superfamily 13 349 2.2E-38 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THITH_14150 cc3258825aea9531aeadf93608d1f7c9 461 SUPERFAMILY SSF103473 10 386 2.09E-54 T 13-10-2018 IPR036259 MFS transporter superfamily THITH_03995 9c132d274b157622ba54dadcc438d62f 39 Pfam PF08031 Berberine and berberine like 9 32 7.5E-8 T 13-10-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 THITH_03995 9c132d274b157622ba54dadcc438d62f 39 Gene3D G3DSA:3.30.465.50 7 33 4.3E-6 T 13-10-2018 THITH_08755 6086e110e3766c05939654c712117114 72 SUPERFAMILY SSF50249 1 70 5.14E-29 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_08755 6086e110e3766c05939654c712117114 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 1.3E-28 T 13-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 THITH_08755 6086e110e3766c05939654c712117114 72 Gene3D G3DSA:2.40.50.140 1 72 1.4E-36 T 13-10-2018 THITH_08755 6086e110e3766c05939654c712117114 72 SMART SM00316 4 72 6.4E-7 T 13-10-2018 IPR022967 RNA-binding domain, S1 THITH_08755 6086e110e3766c05939654c712117114 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 27.082 T 13-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 THITH_08755 6086e110e3766c05939654c712117114 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 70 2.4E-37 T 13-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 THITH_05090 3a8acc4e39367cd10afd2861b347f8f8 69 Pfam PF07311 Dodecin 5 68 3.0E-31 T 13-10-2018 IPR009923 Dodecin THITH_05090 3a8acc4e39367cd10afd2861b347f8f8 69 Gene3D G3DSA:3.30.1660.10 2 69 3.0E-36 T 13-10-2018 IPR025543 Dodecin-like THITH_05090 3a8acc4e39367cd10afd2861b347f8f8 69 SUPERFAMILY SSF89807 5 68 8.63E-27 T 13-10-2018 IPR036694 Dodecin-like superfamily THITH_02710 0032c039a5eaae04e361a4b96aa27c42 307 SUPERFAMILY SSF53335 9 275 1.41E-72 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_02710 0032c039a5eaae04e361a4b96aa27c42 307 Pfam PF04378 Ribosomal RNA large subunit methyltransferase D, RlmJ 34 267 7.4E-59 T 13-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 THITH_02710 0032c039a5eaae04e361a4b96aa27c42 307 Gene3D G3DSA:3.40.50.150 1 289 2.4E-88 T 13-10-2018 THITH_02710 0032c039a5eaae04e361a4b96aa27c42 307 Hamap MF_00934 Ribosomal RNA large subunit methyltransferase J [rlmJ]. 2 268 35.317 T 13-10-2018 IPR007473 Ribosomal RNA large subunit methyltransferase J GO:0008649|GO:0070475 THITH_09145 c75cd1e2cbd70e77224ba5a3748c95c8 418 Pfam PF13533 Biotin-lipoyl like 69 114 5.9E-8 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain THITH_09145 c75cd1e2cbd70e77224ba5a3748c95c8 418 SUPERFAMILY SSF111369 56 278 1.96E-14 T 13-10-2018 THITH_09145 c75cd1e2cbd70e77224ba5a3748c95c8 418 Gene3D G3DSA:1.10.287.470 186 216 1.4E-17 T 13-10-2018 THITH_09145 c75cd1e2cbd70e77224ba5a3748c95c8 418 Gene3D G3DSA:1.10.287.470 101 184 5.0E-15 T 13-10-2018 THITH_09145 c75cd1e2cbd70e77224ba5a3748c95c8 418 Gene3D G3DSA:2.40.420.20 337 407 1.4E-17 T 13-10-2018 THITH_09145 c75cd1e2cbd70e77224ba5a3748c95c8 418 Gene3D G3DSA:2.40.30.170 251 336 1.4E-17 T 13-10-2018 THITH_09145 c75cd1e2cbd70e77224ba5a3748c95c8 418 Gene3D G3DSA:2.40.30.170 55 65 5.0E-15 T 13-10-2018 THITH_09145 c75cd1e2cbd70e77224ba5a3748c95c8 418 Pfam PF13437 HlyD family secretion protein 220 313 8.6E-7 T 13-10-2018 THITH_09145 c75cd1e2cbd70e77224ba5a3748c95c8 418 Gene3D G3DSA:2.40.50.100 217 250 1.4E-17 T 13-10-2018 THITH_09145 c75cd1e2cbd70e77224ba5a3748c95c8 418 Gene3D G3DSA:2.40.50.100 66 100 5.0E-15 T 13-10-2018 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 SMART SM00482 660 866 8.4E-121 T 13-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 SMART SM00279 171 206 6.7E-12 T 13-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 Pfam PF00476 DNA polymerase family A 525 899 4.1E-152 T 13-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 ProSitePatterns PS00447 DNA polymerase family A signature. 728 747 - T 13-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 Pfam PF01612 3'-5' exonuclease 304 490 8.1E-36 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 169 263 3.2E-29 T 13-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 Gene3D G3DSA:1.20.1060.10 517 632 9.8E-39 T 13-10-2018 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 SMART SM00475 5 259 6.4E-125 T 13-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 TIGRFAM TIGR00593 pola: DNA polymerase I 7 902 3.3E-288 T 13-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 SUPERFAMILY SSF47807 169 283 1.94E-34 T 13-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 7 168 3.6E-52 T 13-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 Gene3D G3DSA:3.30.70.370 638 898 7.0E-112 T 13-10-2018 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 Gene3D G3DSA:1.10.150.20 683 826 7.0E-112 T 13-10-2018 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 Gene3D G3DSA:3.30.420.10 301 516 5.5E-70 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 629 651 3.8E-81 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 674 697 3.8E-81 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 704 717 3.8E-81 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 728 753 3.8E-81 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 819 835 3.8E-81 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 765 776 3.8E-81 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 787 798 3.8E-81 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 652 667 3.8E-81 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 PRINTS PR00868 DNA-polymerase family A (pol I) signature 849 862 3.8E-81 T 13-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 SUPERFAMILY SSF53098 303 490 1.2E-53 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 SUPERFAMILY SSF88723 5 168 1.32E-55 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 SUPERFAMILY SSF56672 498 902 4.23E-156 T 13-10-2018 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 Gene3D G3DSA:3.40.50.1010 7 275 5.3E-95 T 13-10-2018 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 SMART SM00474 304 491 5.3E-36 T 13-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 THITH_17135 dd18c03ce89b9baa9b412f82becaf5d5 902 Gene3D G3DSA:1.10.150.20 172 244 5.3E-95 T 13-10-2018 THITH_16835 0a42414c6fea325cf08bed6098169b4e 468 Gene3D G3DSA:3.40.50.300 154 329 1.5E-54 T 13-10-2018 THITH_16835 0a42414c6fea325cf08bed6098169b4e 468 Pfam PF02954 Bacterial regulatory protein, Fis family 423 464 1.1E-12 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_16835 0a42414c6fea325cf08bed6098169b4e 468 SUPERFAMILY SSF52172 22 205 1.57E-40 T 13-10-2018 IPR011006 CheY-like superfamily THITH_16835 0a42414c6fea325cf08bed6098169b4e 468 SUPERFAMILY SSF46689 372 463 3.05E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_16835 0a42414c6fea325cf08bed6098169b4e 468 Gene3D G3DSA:3.40.50.2300 19 153 1.0E-33 T 13-10-2018 THITH_16835 0a42414c6fea325cf08bed6098169b4e 468 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 372 381 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site THITH_16835 0a42414c6fea325cf08bed6098169b4e 468 Gene3D G3DSA:1.10.10.60 421 462 3.1E-14 T 13-10-2018 THITH_16835 0a42414c6fea325cf08bed6098169b4e 468 Pfam PF00158 Sigma-54 interaction domain 164 325 2.5E-56 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THITH_16835 0a42414c6fea325cf08bed6098169b4e 468 Pfam PF00072 Response regulator receiver domain 24 132 1.5E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_16835 0a42414c6fea325cf08bed6098169b4e 468 SUPERFAMILY SSF52540 164 395 7.86E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16835 0a42414c6fea325cf08bed6098169b4e 468 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 187 200 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THITH_16835 0a42414c6fea325cf08bed6098169b4e 468 Gene3D G3DSA:1.10.8.60 330 396 4.3E-22 T 13-10-2018 THITH_16835 0a42414c6fea325cf08bed6098169b4e 468 SMART SM00382 183 323 1.2E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_16835 0a42414c6fea325cf08bed6098169b4e 468 SMART SM00448 22 133 3.6E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 SUPERFAMILY SSF82714 182 263 2.09E-11 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 SUPERFAMILY SSF82866 799 1034 1.27E-46 T 13-10-2018 THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 Gene3D G3DSA:3.30.70.1320 134 324 2.1E-252 T 13-10-2018 THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 Gene3D G3DSA:1.20.1640.10 507 1026 2.1E-252 T 13-10-2018 THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 Gene3D G3DSA:3.30.70.1440 661 857 2.1E-252 T 13-10-2018 THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 Gene3D G3DSA:1.20.1640.10 14 506 2.1E-252 T 13-10-2018 THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 SUPERFAMILY SSF82693 137 320 1.96E-16 T 13-10-2018 THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 PRINTS PR00702 Acriflavin resistance protein family signature 460 483 1.3E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.3E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 PRINTS PR00702 Acriflavin resistance protein family signature 435 458 1.3E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 PRINTS PR00702 Acriflavin resistance protein family signature 327 350 1.3E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 PRINTS PR00702 Acriflavin resistance protein family signature 354 375 1.3E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 PRINTS PR00702 Acriflavin resistance protein family signature 382 406 1.3E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 Gene3D G3DSA:3.30.70.1430 41 807 2.1E-252 T 13-10-2018 THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 Pfam PF00873 AcrB/AcrD/AcrF family 6 1027 1.5E-167 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 Gene3D G3DSA:3.30.70.1430 562 660 2.1E-252 T 13-10-2018 THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 Gene3D G3DSA:3.30.2090.10 177 267 2.1E-252 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 SUPERFAMILY SSF82693 41 133 8.89E-22 T 13-10-2018 THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 Gene3D G3DSA:3.30.2090.10 711 799 2.1E-252 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_01700 c3aa9660f3b9ea85911d9117898f40cf 1042 SUPERFAMILY SSF82866 289 485 1.18E-34 T 13-10-2018 THITH_05985 617df4ee32320ab9fd152b136490dcb8 80 SUPERFAMILY SSF47598 3 47 5.93E-5 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 THITH_06225 b94444dc854b4f510dfdd921a8c5d7b4 173 Gene3D G3DSA:3.10.20.80 4 77 1.6E-30 T 13-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 THITH_06225 b94444dc854b4f510dfdd921a8c5d7b4 173 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 9 172 4.0E-65 T 13-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 THITH_06225 b94444dc854b4f510dfdd921a8c5d7b4 173 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 85 170 8.3E-36 T 13-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 THITH_06225 b94444dc854b4f510dfdd921a8c5d7b4 173 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 3 172 29.118 T 13-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 THITH_06225 b94444dc854b4f510dfdd921a8c5d7b4 173 Gene3D G3DSA:3.30.110.10 78 173 1.0E-35 T 13-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 THITH_06225 b94444dc854b4f510dfdd921a8c5d7b4 173 SUPERFAMILY SSF54364 7 80 1.18E-26 T 13-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 THITH_06225 b94444dc854b4f510dfdd921a8c5d7b4 173 ProSitePatterns PS00938 Initiation factor 3 signature. 60 73 - T 13-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 THITH_06225 b94444dc854b4f510dfdd921a8c5d7b4 173 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 9 77 1.1E-28 T 13-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 THITH_06225 b94444dc854b4f510dfdd921a8c5d7b4 173 SUPERFAMILY SSF55200 85 172 1.83E-30 T 13-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 THITH_14405 1f7a8a256e6fa74e0e90b521bd3d52fa 257 Hamap MF_01092 Cell division protein ZapD [zapD]. 5 255 30.168 T 13-10-2018 IPR009777 Cell division protein ZapD THITH_14405 1f7a8a256e6fa74e0e90b521bd3d52fa 257 Gene3D G3DSA:2.60.440.10 7 255 1.4E-76 T 13-10-2018 IPR027462 Z ring-associated protein D, C-terminal THITH_14405 1f7a8a256e6fa74e0e90b521bd3d52fa 257 Pfam PF07072 Cell division protein 20 230 3.5E-67 T 13-10-2018 IPR009777 Cell division protein ZapD THITH_14405 1f7a8a256e6fa74e0e90b521bd3d52fa 257 SUPERFAMILY SSF160950 5 255 3.14E-71 T 13-10-2018 IPR036268 ZapD domain superfamily THITH_14405 1f7a8a256e6fa74e0e90b521bd3d52fa 257 Gene3D G3DSA:1.10.3900.10 14 181 1.4E-76 T 13-10-2018 THITH_00840 80f1822dfca39b76eb09fa4125b1f8f2 128 Gene3D G3DSA:2.40.10.220 1 118 3.2E-20 T 13-10-2018 THITH_00840 80f1822dfca39b76eb09fa4125b1f8f2 128 Pfam PF07238 PilZ domain 3 101 7.7E-9 T 13-10-2018 IPR009875 PilZ domain GO:0035438 THITH_00840 80f1822dfca39b76eb09fa4125b1f8f2 128 SUPERFAMILY SSF141371 1 115 3.14E-17 T 13-10-2018 THITH_15965 5fdd0b5108ee1e3012f28238c0c71be9 289 Gene3D G3DSA:3.20.20.220 1 289 7.8E-102 T 13-10-2018 THITH_15965 5fdd0b5108ee1e3012f28238c0c71be9 289 Pfam PF02219 Methylenetetrahydrofolate reductase 5 284 1.0E-91 T 13-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 THITH_15965 5fdd0b5108ee1e3012f28238c0c71be9 289 TIGRFAM TIGR00676 fadh2: methylenetetrahydrofolate reductase [NAD(P)H] 11 283 1.0E-101 T 13-10-2018 IPR004620 5,10-methylenetetrahydrofolate reductase GO:0004489|GO:0005829|GO:0009086|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841 THITH_15965 5fdd0b5108ee1e3012f28238c0c71be9 289 SUPERFAMILY SSF51730 4 285 7.85E-97 T 13-10-2018 IPR029041 FAD-linked oxidoreductase-like THITH_01205 5a03996c2797089c678a65801854d933 296 PRINTS PR00478 Phosphoribulokinase family signature 12 29 3.1E-34 T 13-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THITH_01205 5a03996c2797089c678a65801854d933 296 PRINTS PR00478 Phosphoribulokinase family signature 189 212 3.1E-34 T 13-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THITH_01205 5a03996c2797089c678a65801854d933 296 PRINTS PR00478 Phosphoribulokinase family signature 171 188 3.1E-34 T 13-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THITH_01205 5a03996c2797089c678a65801854d933 296 PRINTS PR00478 Phosphoribulokinase family signature 133 151 3.1E-34 T 13-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THITH_01205 5a03996c2797089c678a65801854d933 296 Gene3D G3DSA:3.40.50.300 1 296 2.2E-119 T 13-10-2018 THITH_01205 5a03996c2797089c678a65801854d933 296 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 221 4.1E-74 T 13-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 THITH_01205 5a03996c2797089c678a65801854d933 296 SUPERFAMILY SSF52540 3 293 1.67E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01205 5a03996c2797089c678a65801854d933 296 ProSitePatterns PS00567 Phosphoribulokinase signature. 171 184 - T 13-10-2018 IPR006082 Phosphoribulokinase GO:0005524|GO:0005975|GO:0008974 KEGG: 00710+2.7.1.19|MetaCyc: PWY-5723 THITH_06115 e4c501bb21249ef4374fb22f472f83fb 197 SUPERFAMILY SSF52980 8 185 5.25E-40 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_06115 e4c501bb21249ef4374fb22f472f83fb 197 Pfam PF05685 Putative restriction endonuclease 15 184 4.2E-38 T 13-10-2018 IPR008538 Domain of unknown function DUF820 THITH_06115 e4c501bb21249ef4374fb22f472f83fb 197 Gene3D G3DSA:3.90.1570.10 6 191 1.6E-34 T 13-10-2018 THITH_07420 8725fb32967e5c6af0c34ace40004758 156 Pfam PF08753 NikR C terminal nickel binding domain 55 130 2.6E-27 T 13-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal THITH_07420 8725fb32967e5c6af0c34ace40004758 156 SUPERFAMILY SSF55021 52 134 2.52E-24 T 13-10-2018 THITH_07420 8725fb32967e5c6af0c34ace40004758 156 SUPERFAMILY SSF47598 3 45 1.45E-9 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 THITH_07420 8725fb32967e5c6af0c34ace40004758 156 Hamap MF_00476 Nickel-responsive regulator [nikR]. 2 133 25.481 T 13-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 THITH_07420 8725fb32967e5c6af0c34ace40004758 156 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 43 4.3E-5 T 13-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 THITH_07420 8725fb32967e5c6af0c34ace40004758 156 Gene3D G3DSA:3.30.70.1150 51 134 3.0E-30 T 13-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal THITH_07420 8725fb32967e5c6af0c34ace40004758 156 Gene3D G3DSA:1.10.1220.10 2 48 1.6E-19 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THITH_16150 5a7ab9c8792aeabb01757fcaa71725c5 632 Gene3D G3DSA:3.30.450.40 289 418 4.8E-5 T 13-10-2018 IPR029016 GAF-like domain superfamily THITH_16150 5a7ab9c8792aeabb01757fcaa71725c5 632 Gene3D G3DSA:3.30.565.10 489 617 4.5E-26 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_16150 5a7ab9c8792aeabb01757fcaa71725c5 632 Gene3D G3DSA:1.10.287.130 191 288 1.0E-8 T 13-10-2018 THITH_16150 5a7ab9c8792aeabb01757fcaa71725c5 632 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 34 123 2.1E-9 T 13-10-2018 IPR029095 NarX-like, N-terminal THITH_16150 5a7ab9c8792aeabb01757fcaa71725c5 632 SMART SM00304 193 245 7.5E-13 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_16150 5a7ab9c8792aeabb01757fcaa71725c5 632 Pfam PF07730 Histidine kinase 418 483 6.0E-16 T 13-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 THITH_16150 5a7ab9c8792aeabb01757fcaa71725c5 632 Gene3D G3DSA:1.20.120.960 40 165 3.1E-9 T 13-10-2018 THITH_16150 5a7ab9c8792aeabb01757fcaa71725c5 632 PIRSF PIRSF003167 1 628 8.5E-173 T 13-10-2018 IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing GO:0000155|GO:0000160|GO:0004673|GO:0016021 THITH_16150 5a7ab9c8792aeabb01757fcaa71725c5 632 SUPERFAMILY SSF55874 526 615 2.36E-17 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_16150 5a7ab9c8792aeabb01757fcaa71725c5 632 SUPERFAMILY SSF55781 284 413 3.19E-8 T 13-10-2018 THITH_16150 5a7ab9c8792aeabb01757fcaa71725c5 632 Pfam PF00672 HAMP domain 193 241 2.6E-11 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_16150 5a7ab9c8792aeabb01757fcaa71725c5 632 SUPERFAMILY SSF158472 193 243 4.97E-9 T 13-10-2018 THITH_16150 5a7ab9c8792aeabb01757fcaa71725c5 632 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 525 614 1.2E-9 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_16150 5a7ab9c8792aeabb01757fcaa71725c5 632 SMART SM00387 524 618 7.1E-11 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_07690 22d87ef3072592759bba10f38528d130 154 Pfam PF01928 CYTH domain 3 142 3.9E-12 T 13-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 THITH_07690 22d87ef3072592759bba10f38528d130 154 SUPERFAMILY SSF55154 1 148 8.34E-39 T 13-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 THITH_07690 22d87ef3072592759bba10f38528d130 154 Gene3D G3DSA:2.40.320.10 1 150 1.3E-46 T 13-10-2018 THITH_07690 22d87ef3072592759bba10f38528d130 154 SMART SM01118 2 148 1.1E-21 T 13-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 THITH_07690 22d87ef3072592759bba10f38528d130 154 PIRSF PIRSF016487 1 154 7.4E-60 T 13-10-2018 IPR012042 Inorganic triphosphatase NeuTTM/CthTTM-like THITH_02820 86378710eb9c0da5d5cff9c77660bd17 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 6.9E-19 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 THITH_02820 86378710eb9c0da5d5cff9c77660bd17 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 6.9E-19 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 THITH_02820 86378710eb9c0da5d5cff9c77660bd17 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 6.9E-19 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 THITH_02820 86378710eb9c0da5d5cff9c77660bd17 572 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 6.9E-19 T 13-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 THITH_02820 86378710eb9c0da5d5cff9c77660bd17 572 Gene3D G3DSA:3.90.960.10 239 387 1.8E-234 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 THITH_02820 86378710eb9c0da5d5cff9c77660bd17 572 SUPERFAMILY SSF52954 462 567 1.96E-26 T 13-10-2018 THITH_02820 86378710eb9c0da5d5cff9c77660bd17 572 SUPERFAMILY SSF55681 10 476 3.32E-103 T 13-10-2018 THITH_02820 86378710eb9c0da5d5cff9c77660bd17 572 SUPERFAMILY SSF55826 223 387 3.66E-28 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 THITH_02820 86378710eb9c0da5d5cff9c77660bd17 572 Pfam PF04073 Aminoacyl-tRNA editing domain 255 375 6.2E-25 T 13-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THITH_02820 86378710eb9c0da5d5cff9c77660bd17 572 PIRSF PIRSF001535 1 570 4.4E-260 T 13-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 THITH_02820 86378710eb9c0da5d5cff9c77660bd17 572 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 565 3.5E-232 T 13-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 THITH_02820 86378710eb9c0da5d5cff9c77660bd17 572 Gene3D G3DSA:3.30.930.10 11 463 1.8E-234 T 13-10-2018 THITH_02820 86378710eb9c0da5d5cff9c77660bd17 572 Pfam PF03129 Anticodon binding domain 474 566 6.1E-16 T 13-10-2018 IPR004154 Anticodon-binding THITH_02820 86378710eb9c0da5d5cff9c77660bd17 572 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 457 5.9E-52 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_02820 86378710eb9c0da5d5cff9c77660bd17 572 Gene3D G3DSA:3.40.50.800 4 551 1.8E-234 T 13-10-2018 IPR036621 Anticodon-binding domain superfamily THITH_02820 86378710eb9c0da5d5cff9c77660bd17 572 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 569 42.016 T 13-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 THITH_11740 6209b87799dfe1900857e8a5539ab0ed 639 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 135 291 4.3E-15 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THITH_11740 6209b87799dfe1900857e8a5539ab0ed 639 SUPERFAMILY SSF161098 80 280 3.4E-25 T 13-10-2018 IPR035906 MetI-like superfamily THITH_11740 6209b87799dfe1900857e8a5539ab0ed 639 Gene3D G3DSA:1.10.3720.10 423 635 2.0E-13 T 13-10-2018 IPR035906 MetI-like superfamily THITH_11740 6209b87799dfe1900857e8a5539ab0ed 639 SUPERFAMILY SSF161098 440 629 4.58E-14 T 13-10-2018 IPR035906 MetI-like superfamily THITH_11740 6209b87799dfe1900857e8a5539ab0ed 639 Gene3D G3DSA:1.10.3720.10 70 293 1.5E-31 T 13-10-2018 IPR035906 MetI-like superfamily THITH_06765 f88cf74787babc5414e1ae01db5215d9 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 215 232 1.7E-76 T 13-10-2018 THITH_06765 f88cf74787babc5414e1ae01db5215d9 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 233 251 1.7E-76 T 13-10-2018 THITH_06765 f88cf74787babc5414e1ae01db5215d9 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 160 184 1.7E-76 T 13-10-2018 THITH_06765 f88cf74787babc5414e1ae01db5215d9 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 257 283 1.7E-76 T 13-10-2018 THITH_06765 f88cf74787babc5414e1ae01db5215d9 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 189 212 1.7E-76 T 13-10-2018 THITH_06765 f88cf74787babc5414e1ae01db5215d9 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 71 95 1.7E-76 T 13-10-2018 THITH_06765 f88cf74787babc5414e1ae01db5215d9 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 285 298 1.7E-76 T 13-10-2018 THITH_06765 f88cf74787babc5414e1ae01db5215d9 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 48 70 1.7E-76 T 13-10-2018 THITH_06765 f88cf74787babc5414e1ae01db5215d9 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 117 140 1.7E-76 T 13-10-2018 THITH_06765 f88cf74787babc5414e1ae01db5215d9 353 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 5 317 4.3E-131 T 13-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 THITH_06765 f88cf74787babc5414e1ae01db5215d9 353 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 63 208 2.7E-28 T 13-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_06765 f88cf74787babc5414e1ae01db5215d9 353 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 228 310 3.5E-32 T 13-10-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal THITH_06765 f88cf74787babc5414e1ae01db5215d9 353 Gene3D G3DSA:4.10.480.10 230 341 1.9E-40 T 13-10-2018 IPR037148 [NiFe]-hydrogenase, small subunit, C-terminal domain superfamily THITH_06765 f88cf74787babc5414e1ae01db5215d9 353 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 17 35 1.0E-4 T 13-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THITH_06765 f88cf74787babc5414e1ae01db5215d9 353 SUPERFAMILY SSF56770 49 310 4.06E-83 T 13-10-2018 THITH_06765 f88cf74787babc5414e1ae01db5215d9 353 Gene3D G3DSA:3.40.50.700 47 227 5.9E-60 T 13-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily THITH_06765 f88cf74787babc5414e1ae01db5215d9 353 PIRSF PIRSF000310 6 351 1.7E-127 T 13-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 THITH_17455 0559ff8a46b7c0630ad0522f60af7df9 499 SUPERFAMILY SSF47917 363 417 7.06E-5 T 13-10-2018 THITH_17455 0559ff8a46b7c0630ad0522f60af7df9 499 SUPERFAMILY SSF52540 79 355 1.4E-77 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_17455 0559ff8a46b7c0630ad0522f60af7df9 499 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 132 350 3.1E-62 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_17455 0559ff8a46b7c0630ad0522f60af7df9 499 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 3 459 52.243 T 13-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_17455 0559ff8a46b7c0630ad0522f60af7df9 499 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 341 350 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_17455 0559ff8a46b7c0630ad0522f60af7df9 499 Gene3D G3DSA:3.40.50.12240 1 459 3.2E-162 T 13-10-2018 THITH_11750 60772b1861c4cea9a0fb7d2402b97149 142 Gene3D G3DSA:3.40.50.1010 1 139 2.6E-34 T 13-10-2018 THITH_11750 60772b1861c4cea9a0fb7d2402b97149 142 SUPERFAMILY SSF88723 1 138 8.97E-25 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_11750 60772b1861c4cea9a0fb7d2402b97149 142 Pfam PF01850 PIN domain 3 123 9.7E-9 T 13-10-2018 IPR002716 PIN domain THITH_11750 60772b1861c4cea9a0fb7d2402b97149 142 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 136 9.524 T 13-10-2018 IPR022907 VapC family GO:0004540 THITH_01000 c39a707e9e6a47b2ed95743d0e677907 537 PIRSF PIRSF002741 55 511 8.7E-75 T 13-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 THITH_01000 c39a707e9e6a47b2ed95743d0e677907 537 Gene3D G3DSA:3.40.190.10 34 276 1.3E-46 T 13-10-2018 THITH_01000 c39a707e9e6a47b2ed95743d0e677907 537 Gene3D G3DSA:3.10.105.10 277 500 7.2E-50 T 13-10-2018 THITH_01000 c39a707e9e6a47b2ed95743d0e677907 537 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 445 9.0E-69 T 13-10-2018 IPR000914 Solute-binding protein family 5 domain THITH_01000 c39a707e9e6a47b2ed95743d0e677907 537 SUPERFAMILY SSF53850 48 513 1.61E-101 T 13-10-2018 THITH_17065 a166ad9c5af41fb56efc5d5e9b110408 434 SUPERFAMILY SSF50156 92 186 1.01E-19 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 THITH_17065 a166ad9c5af41fb56efc5d5e9b110408 434 SUPERFAMILY SSF52096 39 370 1.82E-83 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THITH_17065 a166ad9c5af41fb56efc5d5e9b110408 434 Pfam PF03572 Peptidase family S41 202 365 6.3E-56 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 THITH_17065 a166ad9c5af41fb56efc5d5e9b110408 434 Gene3D G3DSA:3.30.750.44 51 341 6.9E-96 T 13-10-2018 THITH_17065 a166ad9c5af41fb56efc5d5e9b110408 434 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 56 373 4.2E-102 T 13-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 THITH_17065 a166ad9c5af41fb56efc5d5e9b110408 434 Gene3D G3DSA:3.90.226.10 191 363 6.9E-96 T 13-10-2018 THITH_17065 a166ad9c5af41fb56efc5d5e9b110408 434 SMART SM00245 176 366 6.0E-74 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 THITH_17065 a166ad9c5af41fb56efc5d5e9b110408 434 SMART SM00228 103 174 2.9E-15 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_17065 a166ad9c5af41fb56efc5d5e9b110408 434 Pfam PF13180 PDZ domain 103 182 6.5E-11 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_17065 a166ad9c5af41fb56efc5d5e9b110408 434 Gene3D G3DSA:2.30.42.10 103 190 6.9E-96 T 13-10-2018 THITH_07785 eee716c0700cc79802b3403b01cbd4dd 477 Gene3D G3DSA:3.40.462.20 218 430 2.5E-110 T 13-10-2018 THITH_07785 eee716c0700cc79802b3403b01cbd4dd 477 Pfam PF08031 Berberine and berberine like 425 470 1.4E-9 T 13-10-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 THITH_07785 eee716c0700cc79802b3403b01cbd4dd 477 Pfam PF01565 FAD binding domain 52 186 1.1E-29 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THITH_07785 eee716c0700cc79802b3403b01cbd4dd 477 Gene3D G3DSA:3.30.43.10 27 105 1.4E-25 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 THITH_07785 eee716c0700cc79802b3403b01cbd4dd 477 SUPERFAMILY SSF56176 26 218 2.66E-53 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 THITH_07785 eee716c0700cc79802b3403b01cbd4dd 477 Gene3D G3DSA:3.30.465.10 119 458 2.5E-110 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 THITH_07785 eee716c0700cc79802b3403b01cbd4dd 477 ProSitePatterns PS00862 Oxygen oxidoreductases covalent FAD-binding site. 52 85 - T 13-10-2018 IPR006093 Oxygen oxidoreductase covalent FAD-binding site GO:0016491|GO:0055114 THITH_00440 8026630b2e67c456fbd8cfef70dfed3c 403 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 18 235 1.3E-68 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THITH_00440 8026630b2e67c456fbd8cfef70dfed3c 403 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 94 112 8.6E-48 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THITH_00440 8026630b2e67c456fbd8cfef70dfed3c 403 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 163 191 8.6E-48 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THITH_00440 8026630b2e67c456fbd8cfef70dfed3c 403 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 112 138 8.6E-48 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THITH_00440 8026630b2e67c456fbd8cfef70dfed3c 403 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 17 44 8.6E-48 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THITH_00440 8026630b2e67c456fbd8cfef70dfed3c 403 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 5 247 16.338 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THITH_00440 8026630b2e67c456fbd8cfef70dfed3c 403 ProSitePatterns PS01218 TatC family signature. 163 182 - T 13-10-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site THITH_00440 8026630b2e67c456fbd8cfef70dfed3c 403 Pfam PF00902 Sec-independent protein translocase protein (TatC) 21 230 2.1E-64 T 13-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 THITH_16510 368e7a604c359b7d09dc5c697a6758ab 309 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 6 309 1.9E-69 T 13-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III THITH_16510 368e7a604c359b7d09dc5c697a6758ab 309 PRINTS PR00605 Class IC cytochrome C signature 137 148 7.7E-6 T 13-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 THITH_16510 368e7a604c359b7d09dc5c697a6758ab 309 PRINTS PR00605 Class IC cytochrome C signature 280 302 7.7E-6 T 13-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 THITH_16510 368e7a604c359b7d09dc5c697a6758ab 309 Gene3D G3DSA:1.10.760.10 102 305 9.7E-51 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_16510 368e7a604c359b7d09dc5c697a6758ab 309 SUPERFAMILY SSF46626 33 210 2.33E-24 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_16510 368e7a604c359b7d09dc5c697a6758ab 309 Gene3D G3DSA:1.10.760.10 183 282 9.7E-51 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_16510 368e7a604c359b7d09dc5c697a6758ab 309 Gene3D G3DSA:1.20.58.1490 1 71 4.2E-21 T 13-10-2018 IPR038414 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal domain superfamily THITH_16510 368e7a604c359b7d09dc5c697a6758ab 309 PIRSF PIRSF000006 1 309 1.5E-69 T 13-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III THITH_16510 368e7a604c359b7d09dc5c697a6758ab 309 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 135 202 1.1E-10 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_16510 368e7a604c359b7d09dc5c697a6758ab 309 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 214 302 2.2E-8 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_16510 368e7a604c359b7d09dc5c697a6758ab 309 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 13 60 1.1E-24 T 13-10-2018 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal THITH_16510 368e7a604c359b7d09dc5c697a6758ab 309 SUPERFAMILY SSF46626 210 308 1.32E-17 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_16295 050fa8a9a045729bfa8d422aafd1140b 249 SUPERFAMILY SSF51206 10 148 1.44E-28 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like THITH_16295 050fa8a9a045729bfa8d422aafd1140b 249 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 178 194 2.4E-5 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THITH_16295 050fa8a9a045729bfa8d422aafd1140b 249 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 194 209 2.4E-5 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THITH_16295 050fa8a9a045729bfa8d422aafd1140b 249 Gene3D G3DSA:2.60.120.10 2 148 3.6E-27 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_16295 050fa8a9a045729bfa8d422aafd1140b 249 Pfam PF00027 Cyclic nucleotide-binding domain 35 118 1.0E-17 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain THITH_16295 050fa8a9a045729bfa8d422aafd1140b 249 Pfam PF13545 Crp-like helix-turn-helix domain 153 226 2.8E-15 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THITH_16295 050fa8a9a045729bfa8d422aafd1140b 249 SUPERFAMILY SSF46785 151 229 4.51E-15 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_16295 050fa8a9a045729bfa8d422aafd1140b 249 SMART SM00100 15 133 4.2E-14 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain THITH_16295 050fa8a9a045729bfa8d422aafd1140b 249 Gene3D G3DSA:1.10.10.10 151 230 3.4E-19 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_16295 050fa8a9a045729bfa8d422aafd1140b 249 SMART SM00419 172 220 1.2E-9 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THITH_13070 1c1be88a74d0ef317159077abe7fc8d8 375 Pfam PF01264 Chorismate synthase 10 345 7.4E-137 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THITH_13070 1c1be88a74d0ef317159077abe7fc8d8 375 PIRSF PIRSF001456 3 366 1.3E-136 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THITH_13070 1c1be88a74d0ef317159077abe7fc8d8 375 ProSitePatterns PS00789 Chorismate synthase signature 3. 319 335 - T 13-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THITH_13070 1c1be88a74d0ef317159077abe7fc8d8 375 SUPERFAMILY SSF103263 4 352 7.19E-146 T 13-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THITH_13070 1c1be88a74d0ef317159077abe7fc8d8 375 Hamap MF_00300 Chorismate synthase [aroC]. 10 352 37.137 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THITH_13070 1c1be88a74d0ef317159077abe7fc8d8 375 Gene3D G3DSA:3.60.150.10 1 362 2.8E-151 T 13-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THITH_13070 1c1be88a74d0ef317159077abe7fc8d8 375 ProSitePatterns PS00787 Chorismate synthase signature 1. 16 31 - T 13-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THITH_13070 1c1be88a74d0ef317159077abe7fc8d8 375 TIGRFAM TIGR00033 aroC: chorismate synthase 11 350 3.1E-137 T 13-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 THITH_14020 61fbfb563f4fdf379e1dbc6ebcbbe08f 457 SMART SM00382 163 306 3.3E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_14020 61fbfb563f4fdf379e1dbc6ebcbbe08f 457 SUPERFAMILY SSF46689 357 457 1.75E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_14020 61fbfb563f4fdf379e1dbc6ebcbbe08f 457 SUPERFAMILY SSF52172 4 187 1.11E-43 T 13-10-2018 IPR011006 CheY-like superfamily THITH_14020 61fbfb563f4fdf379e1dbc6ebcbbe08f 457 Pfam PF00072 Response regulator receiver domain 6 115 9.8E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_14020 61fbfb563f4fdf379e1dbc6ebcbbe08f 457 SUPERFAMILY SSF52540 143 382 5.21E-71 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14020 61fbfb563f4fdf379e1dbc6ebcbbe08f 457 Gene3D G3DSA:3.40.50.300 133 314 1.1E-61 T 13-10-2018 THITH_14020 61fbfb563f4fdf379e1dbc6ebcbbe08f 457 SMART SM00448 4 115 9.0E-36 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_14020 61fbfb563f4fdf379e1dbc6ebcbbe08f 457 Pfam PF00158 Sigma-54 interaction domain 143 309 1.3E-66 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THITH_14020 61fbfb563f4fdf379e1dbc6ebcbbe08f 457 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 229 244 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THITH_14020 61fbfb563f4fdf379e1dbc6ebcbbe08f 457 Gene3D G3DSA:1.10.8.60 315 388 5.7E-19 T 13-10-2018 THITH_14020 61fbfb563f4fdf379e1dbc6ebcbbe08f 457 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 437 457 2.3E-11 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_14020 61fbfb563f4fdf379e1dbc6ebcbbe08f 457 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 420 437 2.3E-11 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_14020 61fbfb563f4fdf379e1dbc6ebcbbe08f 457 Gene3D G3DSA:3.40.50.2300 2 132 6.6E-36 T 13-10-2018 THITH_14020 61fbfb563f4fdf379e1dbc6ebcbbe08f 457 Gene3D G3DSA:1.10.10.60 399 457 1.3E-13 T 13-10-2018 THITH_14020 61fbfb563f4fdf379e1dbc6ebcbbe08f 457 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 356 365 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site THITH_14020 61fbfb563f4fdf379e1dbc6ebcbbe08f 457 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 167 180 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THITH_14020 61fbfb563f4fdf379e1dbc6ebcbbe08f 457 Pfam PF02954 Bacterial regulatory protein, Fis family 414 454 7.5E-14 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_02810 8db537ff92da73c821bb094ae19deb20 117 SUPERFAMILY SSF52833 7 117 5.74E-39 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_02810 8db537ff92da73c821bb094ae19deb20 117 Pfam PF03960 ArsC family 8 116 1.1E-21 T 13-10-2018 IPR006660 Arsenate reductase-like THITH_02810 8db537ff92da73c821bb094ae19deb20 117 Gene3D G3DSA:3.40.30.10 3 117 1.3E-51 T 13-10-2018 THITH_02810 8db537ff92da73c821bb094ae19deb20 117 TIGRFAM TIGR00014 arsC: arsenate reductase (glutaredoxin) 7 117 7.3E-50 T 13-10-2018 IPR006659 Arsenate reductase GO:0008794|GO:0055114 MetaCyc: PWY-4202|MetaCyc: PWY-4621 THITH_12705 80fb671a3f244e421c5f6e9999bc02b3 421 Pfam PF01734 Patatin-like phospholipase 83 264 5.4E-16 T 13-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 THITH_12705 80fb671a3f244e421c5f6e9999bc02b3 421 Gene3D G3DSA:3.40.1090.10 176 279 1.2E-6 T 13-10-2018 THITH_12705 80fb671a3f244e421c5f6e9999bc02b3 421 Gene3D G3DSA:3.40.1090.10 62 175 2.6E-9 T 13-10-2018 THITH_12705 80fb671a3f244e421c5f6e9999bc02b3 421 SUPERFAMILY SSF52151 82 265 1.62E-29 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase THITH_13485 78be9ecfc5c3266a2e94ec5224ece842 361 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 10 319 48.986 T 13-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 THITH_13485 78be9ecfc5c3266a2e94ec5224ece842 361 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 17 352 8.5E-147 T 13-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 THITH_13485 78be9ecfc5c3266a2e94ec5224ece842 361 Pfam PF08331 Domain of unknown function (DUF1730) 65 144 3.5E-22 T 13-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 THITH_13485 78be9ecfc5c3266a2e94ec5224ece842 361 Pfam PF13484 4Fe-4S double cluster binding domain 196 260 1.2E-19 T 13-10-2018 THITH_13485 78be9ecfc5c3266a2e94ec5224ece842 361 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 197 208 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_13485 78be9ecfc5c3266a2e94ec5224ece842 361 SUPERFAMILY SSF46548 143 260 5.75E-19 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_07015 6282b9ce0ec486f26840b2be68561ec3 442 Pfam PF02803 Thiolase, C-terminal domain 295 433 1.1E-40 T 13-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 THITH_07015 6282b9ce0ec486f26840b2be68561ec3 442 Pfam PF00108 Thiolase, N-terminal domain 13 286 5.4E-59 T 13-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 THITH_07015 6282b9ce0ec486f26840b2be68561ec3 442 SUPERFAMILY SSF53901 13 294 3.84E-64 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 THITH_07015 6282b9ce0ec486f26840b2be68561ec3 442 Gene3D G3DSA:3.40.47.10 15 300 3.1E-124 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 THITH_07015 6282b9ce0ec486f26840b2be68561ec3 442 SUPERFAMILY SSF53901 297 433 4.23E-38 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 THITH_07015 6282b9ce0ec486f26840b2be68561ec3 442 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 16 432 1.3E-128 T 13-10-2018 IPR002155 Thiolase GO:0016747 THITH_07015 6282b9ce0ec486f26840b2be68561ec3 442 ProSitePatterns PS00099 Thiolases active site. 415 428 - T 13-10-2018 IPR020610 Thiolase, active site GO:0016747 THITH_07015 6282b9ce0ec486f26840b2be68561ec3 442 Gene3D G3DSA:3.40.47.10 135 430 3.1E-124 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 THITH_07015 6282b9ce0ec486f26840b2be68561ec3 442 ProSitePatterns PS00737 Thiolases signature 2. 380 396 - T 13-10-2018 IPR020613 Thiolase, conserved site GO:0016747 THITH_07015 6282b9ce0ec486f26840b2be68561ec3 442 PIRSF PIRSF000429 8 434 1.0E-126 T 13-10-2018 IPR002155 Thiolase GO:0016747 THITH_14880 998f5234cdfe74fe8ac2592372358367 178 PIRSF PIRSF016481 9 178 6.5E-34 T 13-10-2018 IPR007446 Pilus assembly protein PilP THITH_14880 998f5234cdfe74fe8ac2592372358367 178 Pfam PF04351 Pilus assembly protein, PilP 30 176 4.1E-44 T 13-10-2018 IPR007446 Pilus assembly protein PilP THITH_14880 998f5234cdfe74fe8ac2592372358367 178 Gene3D G3DSA:2.30.30.830 86 177 8.2E-30 T 13-10-2018 THITH_09900 905f26c89ac6b9b6bb3d3b3146db8224 344 SUPERFAMILY SSF51735 2 333 1.6E-73 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_09900 905f26c89ac6b9b6bb3d3b3146db8224 344 TIGRFAM TIGR01472 gmd: GDP-mannose 4,6-dehydratase 2 336 2.1E-140 T 13-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 THITH_09900 905f26c89ac6b9b6bb3d3b3146db8224 344 Gene3D G3DSA:3.40.50.720 4 321 2.2E-143 T 13-10-2018 THITH_09900 905f26c89ac6b9b6bb3d3b3146db8224 344 Gene3D G3DSA:3.90.25.10 187 335 2.2E-143 T 13-10-2018 THITH_09900 905f26c89ac6b9b6bb3d3b3146db8224 344 Hamap MF_00955 GDP-mannose 4,6-dehydratase [gmd]. 2 340 52.246 T 13-10-2018 IPR006368 GDP-mannose 4,6-dehydratase GO:0008446|GO:0019673 KEGG: 00051+4.2.1.47|KEGG: 00520+4.2.1.47|MetaCyc: PWY-5738|MetaCyc: PWY-5739|MetaCyc: PWY-5740|MetaCyc: PWY-66|MetaCyc: PWY-7573|Reactome: R-HSA-6787639 THITH_09900 905f26c89ac6b9b6bb3d3b3146db8224 344 Pfam PF16363 GDP-mannose 4,6 dehydratase 5 330 7.4E-134 T 13-10-2018 IPR016040 NAD(P)-binding domain THITH_14155 33dd12895ed6b52ce25fda769a640bb8 961 Pfam PF00005 ABC transporter 806 859 4.1E-5 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_14155 33dd12895ed6b52ce25fda769a640bb8 961 Gene3D G3DSA:1.20.1580.10 692 829 6.4E-140 T 13-10-2018 THITH_14155 33dd12895ed6b52ce25fda769a640bb8 961 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 924 0.0 T 13-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 THITH_14155 33dd12895ed6b52ce25fda769a640bb8 961 Gene3D G3DSA:3.40.50.300 6 595 1.3E-241 T 13-10-2018 THITH_14155 33dd12895ed6b52ce25fda769a640bb8 961 ProSitePatterns PS00211 ABC transporters family signature. 829 843 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_14155 33dd12895ed6b52ce25fda769a640bb8 961 SUPERFAMILY SSF52540 617 908 4.07E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14155 33dd12895ed6b52ce25fda769a640bb8 961 Gene3D G3DSA:3.40.50.300 614 935 6.4E-140 T 13-10-2018 THITH_14155 33dd12895ed6b52ce25fda769a640bb8 961 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 939 22.431 T 13-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 THITH_14155 33dd12895ed6b52ce25fda769a640bb8 961 Gene3D G3DSA:1.10.8.280 287 403 1.3E-241 T 13-10-2018 THITH_14155 33dd12895ed6b52ce25fda769a640bb8 961 Gene3D G3DSA:1.20.1580.10 90 492 1.3E-241 T 13-10-2018 THITH_14155 33dd12895ed6b52ce25fda769a640bb8 961 ProSitePatterns PS00211 ABC transporters family signature. 487 501 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_14155 33dd12895ed6b52ce25fda769a640bb8 961 Gene3D G3DSA:3.30.190.20 130 239 1.3E-241 T 13-10-2018 THITH_14155 33dd12895ed6b52ce25fda769a640bb8 961 SUPERFAMILY SSF52540 3 569 1.26E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00425 33ce628c2e7ebf5c5929bea505a7e318 470 SUPERFAMILY SSF53448 1 277 2.92E-73 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_00425 33ce628c2e7ebf5c5929bea505a7e318 470 Pfam PF01050 Mannose-6-phosphate isomerase 313 462 1.2E-62 T 13-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 THITH_00425 33ce628c2e7ebf5c5929bea505a7e318 470 Gene3D G3DSA:2.60.120.10 347 458 2.4E-19 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_00425 33ce628c2e7ebf5c5929bea505a7e318 470 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 2 466 2.2E-168 T 13-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 THITH_00425 33ce628c2e7ebf5c5929bea505a7e318 470 SUPERFAMILY SSF51182 179 466 7.79E-73 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily THITH_00425 33ce628c2e7ebf5c5929bea505a7e318 470 Gene3D G3DSA:3.90.550.10 1 346 1.6E-122 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_00425 33ce628c2e7ebf5c5929bea505a7e318 470 Pfam PF00483 Nucleotidyl transferase 4 283 5.9E-56 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 THITH_13440 acaad7b18ce22b7d5f168231d34da750 438 SUPERFAMILY SSF102735 1 131 1.83E-36 T 13-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 THITH_13440 acaad7b18ce22b7d5f168231d34da750 438 Gene3D G3DSA:3.30.70.1050 1 115 5.2E-36 T 13-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 THITH_13440 acaad7b18ce22b7d5f168231d34da750 438 SUPERFAMILY SSF109998 248 427 1.44E-42 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily THITH_13440 acaad7b18ce22b7d5f168231d34da750 438 Gene3D G3DSA:1.10.3120.10 116 416 7.6E-97 T 13-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 THITH_13440 acaad7b18ce22b7d5f168231d34da750 438 SUPERFAMILY SSF54534 89 242 9.43E-32 T 13-10-2018 THITH_13440 acaad7b18ce22b7d5f168231d34da750 438 Pfam PF05697 Bacterial trigger factor protein (TF) 1 144 8.2E-40 T 13-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 THITH_13440 acaad7b18ce22b7d5f168231d34da750 438 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 263 412 2.7E-34 T 13-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 THITH_13440 acaad7b18ce22b7d5f168231d34da750 438 PIRSF PIRSF003095 1 433 2.1E-120 T 13-10-2018 IPR005215 Trigger factor GO:0015031 THITH_13440 acaad7b18ce22b7d5f168231d34da750 438 TIGRFAM TIGR00115 tig: trigger factor 12 411 5.3E-136 T 13-10-2018 IPR005215 Trigger factor GO:0015031 THITH_13440 acaad7b18ce22b7d5f168231d34da750 438 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 158 230 3.9E-12 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain THITH_13440 acaad7b18ce22b7d5f168231d34da750 438 Hamap MF_00303 Trigger factor [tig]. 1 417 21.064 T 13-10-2018 IPR005215 Trigger factor GO:0015031 THITH_13440 acaad7b18ce22b7d5f168231d34da750 438 Gene3D G3DSA:3.10.50.40 150 246 7.6E-97 T 13-10-2018 THITH_02670 ed5487258894cb45f659c42d86270a12 457 Gene3D G3DSA:3.40.50.300 90 285 7.3E-121 T 13-10-2018 THITH_02670 ed5487258894cb45f659c42d86270a12 457 Gene3D G3DSA:1.10.260.30 328 451 9.1E-43 T 13-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 THITH_02670 ed5487258894cb45f659c42d86270a12 457 SUPERFAMILY SSF47446 298 430 2.09E-44 T 13-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 THITH_02670 ed5487258894cb45f659c42d86270a12 457 Gene3D G3DSA:1.20.120.140 5 305 7.3E-121 T 13-10-2018 THITH_02670 ed5487258894cb45f659c42d86270a12 457 Pfam PF02978 Signal peptide binding domain 329 427 2.2E-32 T 13-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 THITH_02670 ed5487258894cb45f659c42d86270a12 457 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 269 282 - T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THITH_02670 ed5487258894cb45f659c42d86270a12 457 SMART SM00382 99 247 2.0E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_02670 ed5487258894cb45f659c42d86270a12 457 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 429 3.4E-173 T 13-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 THITH_02670 ed5487258894cb45f659c42d86270a12 457 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 7.6E-22 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THITH_02670 ed5487258894cb45f659c42d86270a12 457 SUPERFAMILY SSF52540 42 352 1.11E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_02670 ed5487258894cb45f659c42d86270a12 457 Pfam PF00448 SRP54-type protein, GTPase domain 101 296 5.2E-70 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THITH_02670 ed5487258894cb45f659c42d86270a12 457 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 450 33.637 T 13-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 THITH_02670 ed5487258894cb45f659c42d86270a12 457 SMART SM00962 100 296 6.2E-107 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THITH_02670 ed5487258894cb45f659c42d86270a12 457 SMART SM00963 1 86 3.4E-36 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 Pfam PF13426 PAS domain 52 157 1.3E-15 T 13-10-2018 IPR000014 PAS domain THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 Pfam PF13426 PAS domain 176 279 3.9E-16 T 13-10-2018 IPR000014 PAS domain THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 289 466 1.4E-28 T 13-10-2018 IPR000160 GGDEF domain THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 SMART SM00091 166 232 1.2E-6 T 13-10-2018 IPR000014 PAS domain THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 SMART SM00091 39 105 1.5E-7 T 13-10-2018 IPR000014 PAS domain THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 SUPERFAMILY SSF55785 174 277 3.06E-29 T 13-10-2018 IPR035965 PAS domain superfamily THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 Gene3D G3DSA:3.30.450.20 36 167 2.3E-28 T 13-10-2018 THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 SMART SM00052 478 722 4.6E-102 T 13-10-2018 IPR001633 EAL domain THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 SUPERFAMILY SSF55073 296 469 2.2E-38 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 Gene3D G3DSA:3.30.450.20 168 294 2.5E-36 T 13-10-2018 THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 Gene3D G3DSA:3.20.20.450 479 735 3.5E-89 T 13-10-2018 IPR035919 EAL domain superfamily THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 SMART SM00267 280 468 2.6E-50 T 13-10-2018 IPR000160 GGDEF domain THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 Gene3D G3DSA:3.30.70.270 295 473 3.5E-48 T 13-10-2018 THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 Pfam PF00563 EAL domain 484 717 1.1E-62 T 13-10-2018 IPR001633 EAL domain THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 SUPERFAMILY SSF141868 483 727 1.7E-81 T 13-10-2018 IPR035919 EAL domain superfamily THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 164 286 6.8E-19 T 13-10-2018 IPR000014 PAS domain THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 36 165 2.6E-15 T 13-10-2018 IPR000014 PAS domain THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 SUPERFAMILY SSF55785 50 167 8.2E-23 T 13-10-2018 IPR035965 PAS domain superfamily THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 Pfam PF00990 Diguanylate cyclase, GGDEF domain 291 464 2.2E-38 T 13-10-2018 IPR000160 GGDEF domain THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 SMART SM00086 238 280 6.5E-6 T 13-10-2018 IPR001610 PAC motif THITH_13905 6855c6b9dcba8960cde3de5ead963bf1 738 SMART SM00086 117 158 3.9 T 13-10-2018 IPR001610 PAC motif THITH_11390 272b0c747c0c1c96aab9bee063fc6cd3 119 Gene3D G3DSA:1.10.3830.10 3 119 4.2E-36 T 13-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 THITH_11390 272b0c747c0c1c96aab9bee063fc6cd3 119 Pfam PF01219 Prokaryotic diacylglycerol kinase 17 118 2.3E-31 T 13-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 THITH_10645 5f5fa24c12780062d3713d8e98b70c3b 355 SUPERFAMILY SSF53474 65 352 6.14E-37 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_10645 5f5fa24c12780062d3713d8e98b70c3b 355 Pfam PF00561 alpha/beta hydrolase fold 68 333 5.4E-31 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_10645 5f5fa24c12780062d3713d8e98b70c3b 355 Gene3D G3DSA:3.40.50.1820 53 355 4.1E-22 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_10645 5f5fa24c12780062d3713d8e98b70c3b 355 TIGRFAM TIGR01836 PHA_synth_III_C: poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit 5 354 1.4E-170 T 13-10-2018 IPR010125 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit GO:0016746|GO:0042619 THITH_09085 d40e1ed1c270e7142e1ac8034f699c8a 438 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 4 435 39.899 T 13-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 THITH_09085 d40e1ed1c270e7142e1ac8034f699c8a 438 SUPERFAMILY SSF51338 15 434 2.44E-23 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 THITH_09085 d40e1ed1c270e7142e1ac8034f699c8a 438 Gene3D G3DSA:3.20.20.140 63 353 2.7E-163 T 13-10-2018 THITH_09085 d40e1ed1c270e7142e1ac8034f699c8a 438 Pfam PF01979 Amidohydrolase family 60 407 7.7E-71 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 THITH_09085 d40e1ed1c270e7142e1ac8034f699c8a 438 Gene3D G3DSA:2.30.40.10 7 423 2.7E-163 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 THITH_09085 d40e1ed1c270e7142e1ac8034f699c8a 438 SUPERFAMILY SSF51556 62 361 2.04E-97 T 13-10-2018 IPR032466 Metal-dependent hydrolase THITH_15580 ae0b655db7f6ba4008f3babe833aa071 318 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 6 308 6.6E-82 T 13-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 THITH_15580 ae0b655db7f6ba4008f3babe833aa071 318 Pfam PF02911 Formyl transferase, C-terminal domain 207 306 1.6E-23 T 13-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THITH_15580 ae0b655db7f6ba4008f3babe833aa071 318 SUPERFAMILY SSF50486 208 308 8.24E-26 T 13-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 THITH_15580 ae0b655db7f6ba4008f3babe833aa071 318 Gene3D G3DSA:3.10.25.10 210 314 1.4E-26 T 13-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THITH_15580 ae0b655db7f6ba4008f3babe833aa071 318 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 5 310 35.284 T 13-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 THITH_15580 ae0b655db7f6ba4008f3babe833aa071 318 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 136 159 - T 13-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THITH_15580 ae0b655db7f6ba4008f3babe833aa071 318 Gene3D G3DSA:3.40.50.170 1 209 3.1E-78 T 13-10-2018 THITH_15580 ae0b655db7f6ba4008f3babe833aa071 318 Pfam PF00551 Formyl transferase 7 184 4.6E-38 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THITH_15580 ae0b655db7f6ba4008f3babe833aa071 318 SUPERFAMILY SSF53328 4 207 2.09E-62 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THITH_02095 14588ecc1355ea4d03ad18b71bd073e9 344 SUPERFAMILY SSF81342 116 324 6.98E-42 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THITH_02095 14588ecc1355ea4d03ad18b71bd073e9 344 Pfam PF01292 Prokaryotic cytochrome b561 121 299 1.4E-21 T 13-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THITH_02095 14588ecc1355ea4d03ad18b71bd073e9 344 Gene3D G3DSA:1.20.950.20 114 327 9.8E-61 T 13-10-2018 THITH_02095 14588ecc1355ea4d03ad18b71bd073e9 344 TIGRFAM TIGR01583 formate-DH-gamm: formate dehydrogenase, gamma subunit 119 319 5.0E-57 T 13-10-2018 IPR006471 Formate dehydrogenase, gamma subunit GO:0008863|GO:0009326|GO:0016021|GO:0045333 THITH_04030 03f87c505254076a1fb9151dfbfe07ac 219 PIRSF PIRSF000239 11 218 1.2E-76 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THITH_04030 03f87c505254076a1fb9151dfbfe07ac 219 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 167 206 2.2E-18 T 13-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THITH_04030 03f87c505254076a1fb9151dfbfe07ac 219 Hamap MF_00401 Peroxiredoxin. 15 219 45.476 T 13-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 THITH_04030 03f87c505254076a1fb9151dfbfe07ac 219 Gene3D G3DSA:3.30.1020.20 156 219 1.8E-24 T 13-10-2018 THITH_04030 03f87c505254076a1fb9151dfbfe07ac 219 Gene3D G3DSA:3.40.30.10 16 155 1.2E-48 T 13-10-2018 THITH_04030 03f87c505254076a1fb9151dfbfe07ac 219 Pfam PF00578 AhpC/TSA family 18 146 1.3E-35 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THITH_04030 03f87c505254076a1fb9151dfbfe07ac 219 SUPERFAMILY SSF52833 14 218 3.18E-71 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_16375 fe02b63c4b2b36b6faa2ee22ed5cbd60 325 SMART SM00279 186 221 9.1E-11 T 13-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 THITH_16375 fe02b63c4b2b36b6faa2ee22ed5cbd60 325 SUPERFAMILY SSF47807 184 285 1.94E-15 T 13-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily THITH_16375 fe02b63c4b2b36b6faa2ee22ed5cbd60 325 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 184 270 1.3E-16 T 13-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 THITH_16375 fe02b63c4b2b36b6faa2ee22ed5cbd60 325 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 21 159 3.3E-33 T 13-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 THITH_16375 fe02b63c4b2b36b6faa2ee22ed5cbd60 325 SMART SM00475 17 280 1.8E-49 T 13-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 THITH_16375 fe02b63c4b2b36b6faa2ee22ed5cbd60 325 SUPERFAMILY SSF88723 20 172 3.63E-35 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_16375 fe02b63c4b2b36b6faa2ee22ed5cbd60 325 Gene3D G3DSA:3.40.50.1010 21 270 1.9E-58 T 13-10-2018 THITH_16375 fe02b63c4b2b36b6faa2ee22ed5cbd60 325 Gene3D G3DSA:1.10.150.20 187 266 1.9E-58 T 13-10-2018 THITH_08110 e0b6fadea82a8501244e53391e11b80b 332 Pfam PF01136 Peptidase family U32 76 331 6.4E-67 T 13-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 THITH_08110 e0b6fadea82a8501244e53391e11b80b 332 ProSitePatterns PS01276 Peptidase family U32 signature. 161 179 - T 13-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 THITH_01215 0d12efd8c4efb386957d0e2be7357ed5 376 Pfam PF08495 FIST N domain 40 221 7.8E-19 T 13-10-2018 IPR013702 FIST domain, N-terminal THITH_01215 0d12efd8c4efb386957d0e2be7357ed5 376 PIRSF PIRSF018953 2 376 2.8E-44 T 13-10-2018 IPR016741 Uncharacterised conserved protein UCP018953 THITH_01215 0d12efd8c4efb386957d0e2be7357ed5 376 Pfam PF10442 FIST C domain 223 361 4.3E-25 T 13-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 THITH_01215 0d12efd8c4efb386957d0e2be7357ed5 376 SMART SM01204 223 363 4.7E-28 T 13-10-2018 IPR019494 FIST, C-domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 THITH_01215 0d12efd8c4efb386957d0e2be7357ed5 376 SMART SM00897 37 222 4.9E-9 T 13-10-2018 IPR013702 FIST domain, N-terminal THITH_09510 5b8d003beb9c224e1eb8e44027c4267c 628 Pfam PF00501 AMP-binding enzyme 29 427 6.3E-50 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 THITH_09510 5b8d003beb9c224e1eb8e44027c4267c 628 Pfam PF00550 Phosphopantetheine attachment site 537 599 3.0E-12 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain THITH_09510 5b8d003beb9c224e1eb8e44027c4267c 628 Gene3D G3DSA:3.30.300.30 423 522 1.1E-28 T 13-10-2018 THITH_09510 5b8d003beb9c224e1eb8e44027c4267c 628 SUPERFAMILY SSF47336 533 601 2.36E-15 T 13-10-2018 IPR036736 ACP-like superfamily THITH_09510 5b8d003beb9c224e1eb8e44027c4267c 628 SUPERFAMILY SSF56801 18 515 1.44E-100 T 13-10-2018 THITH_09510 5b8d003beb9c224e1eb8e44027c4267c 628 Gene3D G3DSA:3.40.50.12780 16 419 1.8E-75 T 13-10-2018 THITH_09510 5b8d003beb9c224e1eb8e44027c4267c 628 Gene3D G3DSA:3.40.50.1820 530 624 1.4E-22 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_09510 5b8d003beb9c224e1eb8e44027c4267c 628 ProSitePatterns PS00455 Putative AMP-binding domain signature. 167 178 - T 13-10-2018 IPR020845 AMP-binding, conserved site THITH_09510 5b8d003beb9c224e1eb8e44027c4267c 628 ProSitePatterns PS00012 Phosphopantetheine attachment site. 559 574 - T 13-10-2018 IPR006162 Phosphopantetheine attachment site THITH_09510 5b8d003beb9c224e1eb8e44027c4267c 628 SMART SM00823 Phosphopantetheine attachment site 535 604 0.0018 T 13-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 THITH_09510 5b8d003beb9c224e1eb8e44027c4267c 628 Pfam PF13193 AMP-binding enzyme C-terminal domain 436 508 6.6E-11 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain THITH_12545 3201e31b87e3783227e13e463baf8452 426 Pfam PF04285 Protein of unknown function (DUF444) 4 420 1.6E-168 T 13-10-2018 IPR006698 Uncharacterised protein family UPF0229 THITH_12545 3201e31b87e3783227e13e463baf8452 426 Hamap MF_01232 UPF0229 protein YeaH [yeaH]. 1 424 36.425 T 13-10-2018 IPR006698 Uncharacterised protein family UPF0229 THITH_12825 cdc0980c01e2f14d00800270adc4f5d0 976 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 635 749 1.4E-5 T 13-10-2018 IPR000014 PAS domain THITH_12825 cdc0980c01e2f14d00800270adc4f5d0 976 Gene3D G3DSA:1.10.287.130 747 820 8.2E-17 T 13-10-2018 THITH_12825 cdc0980c01e2f14d00800270adc4f5d0 976 Pfam PF00989 PAS fold 638 738 5.6E-6 T 13-10-2018 IPR013767 PAS fold GO:0006355 THITH_12825 cdc0980c01e2f14d00800270adc4f5d0 976 PRINTS PR00344 Bacterial sensor protein C-terminal signature 934 952 2.0E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_12825 cdc0980c01e2f14d00800270adc4f5d0 976 PRINTS PR00344 Bacterial sensor protein C-terminal signature 958 971 2.0E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_12825 cdc0980c01e2f14d00800270adc4f5d0 976 PRINTS PR00344 Bacterial sensor protein C-terminal signature 921 931 2.0E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_12825 cdc0980c01e2f14d00800270adc4f5d0 976 PRINTS PR00344 Bacterial sensor protein C-terminal signature 903 917 2.0E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_12825 cdc0980c01e2f14d00800270adc4f5d0 976 SUPERFAMILY SSF55785 634 684 1.79E-7 T 13-10-2018 IPR035965 PAS domain superfamily THITH_12825 cdc0980c01e2f14d00800270adc4f5d0 976 Gene3D G3DSA:3.30.565.10 827 976 6.9E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_12825 cdc0980c01e2f14d00800270adc4f5d0 976 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 869 973 2.6E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_12825 cdc0980c01e2f14d00800270adc4f5d0 976 SMART SM00091 635 703 4.7E-4 T 13-10-2018 IPR000014 PAS domain THITH_12825 cdc0980c01e2f14d00800270adc4f5d0 976 SUPERFAMILY SSF55874 825 972 2.75E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_12825 cdc0980c01e2f14d00800270adc4f5d0 976 Gene3D G3DSA:3.30.450.20 626 746 1.6E-10 T 13-10-2018 THITH_12825 cdc0980c01e2f14d00800270adc4f5d0 976 SMART SM00388 758 823 4.1E-13 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_12825 cdc0980c01e2f14d00800270adc4f5d0 976 SMART SM00387 866 974 1.8E-30 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_12825 cdc0980c01e2f14d00800270adc4f5d0 976 Pfam PF00512 His Kinase A (phospho-acceptor) domain 759 821 1.1E-12 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_12825 cdc0980c01e2f14d00800270adc4f5d0 976 SUPERFAMILY SSF47384 754 821 1.1E-11 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_10625 e617dfe4e4eba19298298afc38280ffc 341 SUPERFAMILY SSF52913 181 277 5.36E-22 T 13-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily THITH_10625 e617dfe4e4eba19298298afc38280ffc 341 Gene3D G3DSA:3.65.10.20 4 325 1.1E-100 T 13-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily THITH_10625 e617dfe4e4eba19298298afc38280ffc 341 Pfam PF01137 RNA 3'-terminal phosphate cyclase 8 327 2.6E-65 T 13-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain THITH_10625 e617dfe4e4eba19298298afc38280ffc 341 Gene3D G3DSA:3.30.360.20 182 275 1.1E-100 T 13-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily THITH_10625 e617dfe4e4eba19298298afc38280ffc 341 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 180 274 4.6E-14 T 13-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain THITH_10625 e617dfe4e4eba19298298afc38280ffc 341 SUPERFAMILY SSF55205 1 220 1.57E-47 T 13-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 THITH_10625 e617dfe4e4eba19298298afc38280ffc 341 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 2 326 8.2E-98 T 13-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 THITH_10625 e617dfe4e4eba19298298afc38280ffc 341 PIRSF PIRSF005378 1 340 3.5E-89 T 13-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 THITH_12185 fc10785e7583e1308def20336eac664a 541 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 15 34 2.0E-11 T 13-10-2018 THITH_12185 fc10785e7583e1308def20336eac664a 541 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 355 377 2.0E-11 T 13-10-2018 THITH_12185 fc10785e7583e1308def20336eac664a 541 Gene3D G3DSA:3.90.700.10 248 358 1.0E-155 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_12185 fc10785e7583e1308def20336eac664a 541 Pfam PF02910 Fumarate reductase flavoprotein C-term 443 525 4.8E-12 T 13-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_12185 fc10785e7583e1308def20336eac664a 541 SUPERFAMILY SSF56425 238 353 5.53E-43 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_12185 fc10785e7583e1308def20336eac664a 541 Gene3D G3DSA:1.20.58.100 427 539 2.9E-37 T 13-10-2018 THITH_12185 fc10785e7583e1308def20336eac664a 541 PIRSF PIRSF000171 4 533 4.7E-30 T 13-10-2018 THITH_12185 fc10785e7583e1308def20336eac664a 541 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 12 522 5.4E-190 T 13-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 THITH_12185 fc10785e7583e1308def20336eac664a 541 SUPERFAMILY SSF46977 427 527 1.19E-28 T 13-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_12185 fc10785e7583e1308def20336eac664a 541 Pfam PF00890 FAD binding domain 14 392 1.6E-100 T 13-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_12185 fc10785e7583e1308def20336eac664a 541 Gene3D G3DSA:3.50.50.60 14 404 1.0E-155 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_12185 fc10785e7583e1308def20336eac664a 541 SUPERFAMILY SSF51905 9 450 6.49E-73 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_09270 186da9f532a9e061ff1cf1055a2a32be 401 Gene3D G3DSA:1.10.10.680 186 270 2.9E-34 T 13-10-2018 THITH_09270 186da9f532a9e061ff1cf1055a2a32be 401 Gene3D G3DSA:3.40.1350.10 271 392 2.9E-34 T 13-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 THITH_09270 186da9f532a9e061ff1cf1055a2a32be 401 SUPERFAMILY SSF52980 1 396 3.22E-45 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_09270 186da9f532a9e061ff1cf1055a2a32be 401 Pfam PF09002 Domain of unknown function (DUF1887) 1 394 4.9E-77 T 13-10-2018 IPR015093 Protein of unknown function DUF1887 THITH_09270 186da9f532a9e061ff1cf1055a2a32be 401 Gene3D G3DSA:3.40.50.10770 1 138 3.5E-13 T 13-10-2018 THITH_07510 6b4118838fd754f1336661095e208c33 257 Pfam PF12800 4Fe-4S binding domain 134 153 0.22 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_07510 6b4118838fd754f1336661095e208c33 257 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 182 193 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_07510 6b4118838fd754f1336661095e208c33 257 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 59 70 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_07510 6b4118838fd754f1336661095e208c33 257 TIGRFAM TIGR00397 mauM_napG: MauM/NapG family ferredoxin-type protein 7 212 6.7E-62 T 13-10-2018 IPR004494 MauM/NapG ferredoxin-type protein THITH_07510 6b4118838fd754f1336661095e208c33 257 SUPERFAMILY SSF54862 58 200 7.67E-24 T 13-10-2018 THITH_07510 6b4118838fd754f1336661095e208c33 257 Pfam PF00037 4Fe-4S binding domain 176 195 4.2E-5 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_07510 6b4118838fd754f1336661095e208c33 257 Pfam PF12838 4Fe-4S dicluster domain 59 113 1.8E-9 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_07510 6b4118838fd754f1336661095e208c33 257 Gene3D G3DSA:3.30.70.20 51 130 8.6E-13 T 13-10-2018 THITH_07510 6b4118838fd754f1336661095e208c33 257 Gene3D G3DSA:3.30.70.20 133 215 6.6E-12 T 13-10-2018 THITH_10940 301bede750a0414a2fe21eee1aa36157 492 Gene3D G3DSA:3.40.50.300 205 379 8.6E-21 T 13-10-2018 THITH_10940 301bede750a0414a2fe21eee1aa36157 492 Gene3D G3DSA:3.40.50.300 3 102 2.1E-9 T 13-10-2018 THITH_10940 301bede750a0414a2fe21eee1aa36157 492 SUPERFAMILY SSF52540 9 384 7.08E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_10940 301bede750a0414a2fe21eee1aa36157 492 Pfam PF05872 Bacterial protein of unknown function (DUF853) 11 492 4.8E-217 T 13-10-2018 IPR033186 Helicase HerA-like C-terminal THITH_02125 e26c2bc52552127fb7548a4b7420636a 472 SUPERFAMILY SSF54862 84 425 5.71E-36 T 13-10-2018 THITH_02125 e26c2bc52552127fb7548a4b7420636a 472 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 372 383 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_02125 e26c2bc52552127fb7548a4b7420636a 472 Pfam PF00037 4Fe-4S binding domain 133 155 1.8E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_02125 e26c2bc52552127fb7548a4b7420636a 472 Gene3D G3DSA:3.30.70.20 106 167 8.3E-12 T 13-10-2018 THITH_02125 e26c2bc52552127fb7548a4b7420636a 472 Gene3D G3DSA:3.30.70.20 335 407 1.7E-11 T 13-10-2018 THITH_02125 e26c2bc52552127fb7548a4b7420636a 472 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 341 352 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_02125 e26c2bc52552127fb7548a4b7420636a 472 Pfam PF13187 4Fe-4S dicluster domain 340 387 1.5E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 511 517 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 Gene3D G3DSA:2.70.150.20 295 411 1.8E-40 T 13-10-2018 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 PRINTS PR00942 Copper-transporting ATPase 1 signature 38 61 4.6E-8 T 13-10-2018 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 PRINTS PR00942 Copper-transporting ATPase 1 signature 203 223 4.6E-8 T 13-10-2018 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 PRINTS PR00942 Copper-transporting ATPase 1 signature 223 248 4.6E-8 T 13-10-2018 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 PRINTS PR00942 Copper-transporting ATPase 1 signature 12 37 4.6E-8 T 13-10-2018 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 ProSitePatterns PS01047 Heavy-metal-associated domain. 83 112 - T 13-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 240 818 9.8E-192 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 279 788 1.0E-88 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 Gene3D G3DSA:3.40.50.1000 490 761 1.8E-90 T 13-10-2018 IPR023214 HAD superfamily THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 Pfam PF00122 E1-E2 ATPase 308 487 3.6E-56 T 13-10-2018 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 SUPERFAMILY SSF55008 9 75 2.62E-18 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 Pfam PF00702 haloacid dehalogenase-like hydrolase 506 722 3.4E-44 T 13-10-2018 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 Gene3D G3DSA:3.40.1110.10 520 641 1.8E-90 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 Gene3D G3DSA:3.30.70.100 76 145 6.6E-21 T 13-10-2018 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 Gene3D G3DSA:3.30.70.100 13 75 6.2E-20 T 13-10-2018 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 732 744 9.7E-29 T 13-10-2018 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 634 645 9.7E-29 T 13-10-2018 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 709 728 9.7E-29 T 13-10-2018 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 656 666 9.7E-29 T 13-10-2018 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 357 371 9.7E-29 T 13-10-2018 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 509 523 9.7E-29 T 13-10-2018 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 SUPERFAMILY SSF81653 310 407 4.58E-29 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 SUPERFAMILY SSF56784 507 816 3.08E-63 T 13-10-2018 IPR036412 HAD-like superfamily THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 Pfam PF00403 Heavy-metal-associated domain 15 73 3.5E-13 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 Pfam PF00403 Heavy-metal-associated domain 83 141 5.1E-14 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 SUPERFAMILY SSF55008 78 147 7.33E-20 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 ProSitePatterns PS01047 Heavy-metal-associated domain. 17 46 - T 13-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 222 819 4.9E-187 T 13-10-2018 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 SUPERFAMILY SSF81665 257 809 1.31E-13 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 82 142 4.0E-9 T 13-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 THITH_08625 c98118f729d9489eaa7b9c3fb0bcba00 827 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 13 73 2.6E-10 T 13-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 THITH_07525 7486132cf311df01266ae268cb45650d 159 TIGRFAM TIGR00402 napF: ferredoxin-type protein NapF 2 138 7.9E-33 T 13-10-2018 IPR004496 Ferredoxin-type protein NapF GO:0051539 THITH_07525 7486132cf311df01266ae268cb45650d 159 Pfam PF13237 4Fe-4S dicluster domain 14 58 1.3E-5 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_07525 7486132cf311df01266ae268cb45650d 159 Pfam PF00037 4Fe-4S binding domain 118 138 2.3E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_07525 7486132cf311df01266ae268cb45650d 159 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 16 27 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_07525 7486132cf311df01266ae268cb45650d 159 Hamap MF_02201 Ferredoxin-type protein NapF [napF]. 4 144 22.215 T 13-10-2018 IPR004496 Ferredoxin-type protein NapF GO:0051539 THITH_07525 7486132cf311df01266ae268cb45650d 159 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 123 134 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_07525 7486132cf311df01266ae268cb45650d 159 Gene3D G3DSA:3.30.70.20 12 66 1.3E-8 T 13-10-2018 THITH_07525 7486132cf311df01266ae268cb45650d 159 Gene3D G3DSA:3.30.70.20 81 141 7.5E-10 T 13-10-2018 THITH_07525 7486132cf311df01266ae268cb45650d 159 SUPERFAMILY SSF54862 11 140 1.88E-14 T 13-10-2018 THITH_15495 fcb15574e29b8d0b8b95e0977f66fc25 202 SMART SM00382 24 199 3.8E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_15495 fcb15574e29b8d0b8b95e0977f66fc25 202 Pfam PF00005 ABC transporter 17 150 9.6E-26 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_15495 fcb15574e29b8d0b8b95e0977f66fc25 202 Gene3D G3DSA:3.40.50.300 11 202 1.1E-41 T 13-10-2018 THITH_15495 fcb15574e29b8d0b8b95e0977f66fc25 202 ProSitePatterns PS00211 ABC transporters family signature. 122 136 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_15495 fcb15574e29b8d0b8b95e0977f66fc25 202 SUPERFAMILY SSF52540 15 201 5.98E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_09655 7a4f744bd052a9035027a11e41c69bd1 914 SMART SM00086 687 729 3.4E-4 T 13-10-2018 IPR001610 PAC motif THITH_09655 7a4f744bd052a9035027a11e41c69bd1 914 SMART SM00091 614 680 3.0E-9 T 13-10-2018 IPR000014 PAS domain THITH_09655 7a4f744bd052a9035027a11e41c69bd1 914 SMART SM00267 729 906 4.5E-57 T 13-10-2018 IPR000160 GGDEF domain THITH_09655 7a4f744bd052a9035027a11e41c69bd1 914 SUPERFAMILY SSF55785 605 727 1.77E-22 T 13-10-2018 IPR035965 PAS domain superfamily THITH_09655 7a4f744bd052a9035027a11e41c69bd1 914 Gene3D G3DSA:3.30.450.350 326 528 9.1E-12 T 13-10-2018 THITH_09655 7a4f744bd052a9035027a11e41c69bd1 914 SMART SM01079 321 517 2.1E-14 T 13-10-2018 IPR006189 CHASE domain THITH_09655 7a4f744bd052a9035027a11e41c69bd1 914 Pfam PF00989 PAS fold 615 726 6.5E-18 T 13-10-2018 IPR013767 PAS fold GO:0006355 THITH_09655 7a4f744bd052a9035027a11e41c69bd1 914 Pfam PF00990 Diguanylate cyclase, GGDEF domain 740 902 2.8E-46 T 13-10-2018 IPR000160 GGDEF domain THITH_09655 7a4f744bd052a9035027a11e41c69bd1 914 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 738 905 2.9E-44 T 13-10-2018 IPR000160 GGDEF domain THITH_09655 7a4f744bd052a9035027a11e41c69bd1 914 SUPERFAMILY SSF55073 745 905 3.14E-48 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_09655 7a4f744bd052a9035027a11e41c69bd1 914 Gene3D G3DSA:3.30.70.270 733 908 1.1E-58 T 13-10-2018 THITH_09655 7a4f744bd052a9035027a11e41c69bd1 914 Gene3D G3DSA:3.30.450.20 606 727 7.3E-25 T 13-10-2018 THITH_09655 7a4f744bd052a9035027a11e41c69bd1 914 Pfam PF03924 CHASE domain 324 510 4.0E-23 T 13-10-2018 IPR006189 CHASE domain THITH_09655 7a4f744bd052a9035027a11e41c69bd1 914 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 611 735 1.1E-18 T 13-10-2018 IPR000014 PAS domain THITH_12855 aec1f74299871ccc8e4f3ea13a6b32a6 235 Pfam PF00929 Exonuclease 47 209 3.2E-20 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THITH_12855 aec1f74299871ccc8e4f3ea13a6b32a6 235 Gene3D G3DSA:3.30.420.10 38 217 2.9E-37 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_12855 aec1f74299871ccc8e4f3ea13a6b32a6 235 SMART SM00479 44 218 4.0E-26 T 13-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III THITH_12855 aec1f74299871ccc8e4f3ea13a6b32a6 235 SUPERFAMILY SSF53098 40 215 5.6E-39 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_14660 6bacffa2156f30ce86be98d71cf55d58 473 Pfam PF04963 Sigma-54 factor, core binding domain 106 299 1.2E-58 T 13-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 THITH_14660 6bacffa2156f30ce86be98d71cf55d58 473 PIRSF PIRSF000774 1 473 1.2E-152 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 THITH_14660 6bacffa2156f30ce86be98d71cf55d58 473 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 4 49 9.6E-15 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 THITH_14660 6bacffa2156f30ce86be98d71cf55d58 473 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 10 470 7.7E-144 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 THITH_14660 6bacffa2156f30ce86be98d71cf55d58 473 Gene3D G3DSA:1.10.10.60 413 470 1.9E-21 T 13-10-2018 THITH_14660 6bacffa2156f30ce86be98d71cf55d58 473 PRINTS PR00045 Sigma-54 factor signature 388 399 3.1E-32 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 THITH_14660 6bacffa2156f30ce86be98d71cf55d58 473 PRINTS PR00045 Sigma-54 factor signature 446 464 3.1E-32 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 THITH_14660 6bacffa2156f30ce86be98d71cf55d58 473 PRINTS PR00045 Sigma-54 factor signature 182 199 3.1E-32 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 THITH_14660 6bacffa2156f30ce86be98d71cf55d58 473 PRINTS PR00045 Sigma-54 factor signature 372 384 3.1E-32 T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 THITH_14660 6bacffa2156f30ce86be98d71cf55d58 473 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 360 379 - T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 THITH_14660 6bacffa2156f30ce86be98d71cf55d58 473 Gene3D G3DSA:1.10.10.1330 114 230 2.9E-23 T 13-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily THITH_14660 6bacffa2156f30ce86be98d71cf55d58 473 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 451 458 - T 13-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 THITH_14660 6bacffa2156f30ce86be98d71cf55d58 473 Pfam PF04552 Sigma-54, DNA binding domain 313 471 2.0E-67 T 13-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding THITH_03375 51b3d888e724d9e499ea29439550e265 75 Pfam PF09720 Putative addiction module component 15 66 1.1E-11 T 13-10-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module THITH_12290 5c1396711773fbb1cf0b4483ead90446 184 Gene3D G3DSA:3.40.980.10 6 184 6.9E-63 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily THITH_12290 5c1396711773fbb1cf0b4483ead90446 184 SMART SM00852 10 156 6.0E-30 T 13-10-2018 IPR001453 MoaB/Mog domain THITH_12290 5c1396711773fbb1cf0b4483ead90446 184 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 8 150 2.1E-38 T 13-10-2018 IPR001453 MoaB/Mog domain THITH_12290 5c1396711773fbb1cf0b4483ead90446 184 SUPERFAMILY SSF53218 7 177 2.22E-46 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily THITH_12290 5c1396711773fbb1cf0b4483ead90446 184 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 72 85 - T 13-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 THITH_12290 5c1396711773fbb1cf0b4483ead90446 184 Pfam PF00994 Probable molybdopterin binding domain 10 154 3.5E-31 T 13-10-2018 IPR001453 MoaB/Mog domain THITH_17165 f7af80ad5fb99bf04fb32ba05e6f2bac 210 Gene3D G3DSA:3.40.30.10 19 208 1.4E-44 T 13-10-2018 THITH_17165 f7af80ad5fb99bf04fb32ba05e6f2bac 210 ProSitePatterns PS00194 Thioredoxin family active site. 51 69 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 THITH_17165 f7af80ad5fb99bf04fb32ba05e6f2bac 210 PIRSF PIRSF001488 4 210 8.7E-36 T 13-10-2018 IPR023205 Thiol:disulphide interchange protein DsbA/DsbL THITH_17165 f7af80ad5fb99bf04fb32ba05e6f2bac 210 Pfam PF01323 DSBA-like thioredoxin domain 96 186 1.3E-15 T 13-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 THITH_17165 f7af80ad5fb99bf04fb32ba05e6f2bac 210 SUPERFAMILY SSF52833 28 205 2.01E-36 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_17245 d243597a63e0de922a33d7e551e9d08d 413 Pfam PF07687 Peptidase dimerisation domain 213 313 8.5E-5 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain THITH_17245 d243597a63e0de922a33d7e551e9d08d 413 Gene3D G3DSA:3.30.70.360 213 328 5.8E-126 T 13-10-2018 THITH_17245 d243597a63e0de922a33d7e551e9d08d 413 Gene3D G3DSA:3.40.630.10 22 403 5.8E-126 T 13-10-2018 THITH_17245 d243597a63e0de922a33d7e551e9d08d 413 SUPERFAMILY SSF53187 4 410 6.01E-76 T 13-10-2018 THITH_17245 d243597a63e0de922a33d7e551e9d08d 413 Pfam PF01546 Peptidase family M20/M25/M40 79 405 1.0E-29 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 THITH_17245 d243597a63e0de922a33d7e551e9d08d 413 SUPERFAMILY SSF55031 213 329 2.27E-24 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain THITH_17245 d243597a63e0de922a33d7e551e9d08d 413 PIRSF PIRSF001235 4 413 6.9E-136 T 13-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 THITH_17245 d243597a63e0de922a33d7e551e9d08d 413 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 9 408 4.4E-109 T 13-10-2018 IPR010158 Amidase, carbamoylase-type GO:0016813 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 SUPERFAMILY SSF51905 149 312 6.1E-30 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 Gene3D G3DSA:3.50.50.60 115 249 2.8E-93 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 SUPERFAMILY SSF55124 501 633 1.37E-27 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 Gene3D G3DSA:3.30.413.10 638 792 7.4E-35 T 13-10-2018 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 SUPERFAMILY SSF56014 640 799 1.19E-50 T 13-10-2018 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 2.2E-20 T 13-10-2018 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 2.2E-20 T 13-10-2018 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 262 284 2.2E-20 T 13-10-2018 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 2.2E-20 T 13-10-2018 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 2.2E-20 T 13-10-2018 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 Gene3D G3DSA:3.30.390.30 321 381 1.4E-6 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 Gene3D G3DSA:3.50.50.60 12 285 2.8E-93 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 285 1.2E-52 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 566 629 2.5E-14 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 PRINTS PR00397 Sirohaem Fe-binding site signature 686 704 1.4E-6 T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 PRINTS PR00397 Sirohaem Fe-binding site signature 643 661 1.4E-6 T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 Pfam PF04324 BFD-like [2Fe-2S] binding domain 427 475 2.4E-12 T 13-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 Pfam PF04324 BFD-like [2Fe-2S] binding domain 490 540 1.9E-14 T 13-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 Gene3D G3DSA:1.10.10.1100 426 479 2.6E-8 T 13-10-2018 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 SUPERFAMILY SSF51905 8 198 2.24E-44 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 686 702 - T 13-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 11 787 4.1E-286 T 13-10-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 277 284 4.4E-13 T 13-10-2018 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 4.4E-13 T 13-10-2018 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 4.4E-13 T 13-10-2018 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 252 4.4E-13 T 13-10-2018 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 639 776 1.3E-26 T 13-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THITH_05400 ff6c186a9989fc0bb782488e1f8d8c0f 826 PIRSF PIRSF037149 3 825 0.0 T 13-10-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 THITH_01120 a8141a48d2ab0369803fd8a76e6422e8 74 Pfam PF09720 Putative addiction module component 12 65 9.3E-14 T 13-10-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module THITH_01120 a8141a48d2ab0369803fd8a76e6422e8 74 TIGRFAM TIGR02574 stabl_TIGR02574: putative addiction module component, TIGR02574 family 9 71 4.5E-10 T 13-10-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 Pfam PF16658 Class II release factor RF3, C-terminal domain 383 510 3.7E-45 T 13-10-2018 IPR032090 Peptide chain release factor 3, C-terminal THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 SUPERFAMILY SSF54980 389 464 7.91E-17 T 13-10-2018 IPR035647 EF-G domain III/V-like THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 156 8.4E-19 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 Gene3D G3DSA:3.40.50.300 107 271 2.0E-112 T 13-10-2018 THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 PRINTS PR00315 GTP-binding elongation factor signature 98 109 3.9E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 PRINTS PR00315 GTP-binding elongation factor signature 134 143 3.9E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 PRINTS PR00315 GTP-binding elongation factor signature 82 92 3.9E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 PRINTS PR00315 GTP-binding elongation factor signature 62 70 3.9E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 PRINTS PR00315 GTP-binding elongation factor signature 12 25 3.9E-11 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 Gene3D G3DSA:3.40.50.300 69 375 2.0E-112 T 13-10-2018 THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 Pfam PF03144 Elongation factor Tu domain 2 310 376 3.7E-9 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 55 70 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 SUPERFAMILY SSF52540 6 273 4.99E-89 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 SUPERFAMILY SSF50447 257 389 2.87E-30 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 Gene3D G3DSA:3.30.70.3280 386 525 1.0E-50 T 13-10-2018 IPR038467 Peptide chain release factor 3, C-terminal domain superfamily THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 Hamap MF_00072 Peptide chain release factor 3 [prfC]. 1 523 53.475 T 13-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 Pfam PF00009 Elongation factor Tu GTP binding domain 10 273 9.3E-49 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_03750 02fae88b23d4e6816d1872ab1568d358 529 TIGRFAM TIGR00503 prfC: peptide chain release factor 3 5 525 2.2E-264 T 13-10-2018 IPR004548 Peptide chain release factor 3 GO:0003924|GO:0005737|GO:0006415 THITH_01435 c8361faf95af007c4afcedd994cdc305 108 PRINTS PR00421 Thioredoxin family signature 32 41 7.7E-10 T 13-10-2018 THITH_01435 c8361faf95af007c4afcedd994cdc305 108 PRINTS PR00421 Thioredoxin family signature 24 32 7.7E-10 T 13-10-2018 THITH_01435 c8361faf95af007c4afcedd994cdc305 108 PRINTS PR00421 Thioredoxin family signature 72 83 7.7E-10 T 13-10-2018 THITH_01435 c8361faf95af007c4afcedd994cdc305 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 107 1.9E-39 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THITH_01435 c8361faf95af007c4afcedd994cdc305 108 Pfam PF00085 Thioredoxin 5 107 5.1E-34 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 THITH_01435 c8361faf95af007c4afcedd994cdc305 108 Gene3D G3DSA:3.40.30.10 4 108 3.2E-35 T 13-10-2018 THITH_01435 c8361faf95af007c4afcedd994cdc305 108 SUPERFAMILY SSF52833 3 108 7.08E-41 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_01435 c8361faf95af007c4afcedd994cdc305 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 THITH_01435 c8361faf95af007c4afcedd994cdc305 108 PIRSF PIRSF000077 2 108 1.9E-45 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THITH_14730 a0032461f7f9059ddc60a7b353c4ca68 264 Pfam PF04333 MlaA lipoprotein 35 228 1.8E-72 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 THITH_14730 a0032461f7f9059ddc60a7b353c4ca68 264 PRINTS PR01805 VacJ lipoprotein signature 139 156 1.5E-22 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 THITH_14730 a0032461f7f9059ddc60a7b353c4ca68 264 PRINTS PR01805 VacJ lipoprotein signature 36 49 1.5E-22 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 THITH_14730 a0032461f7f9059ddc60a7b353c4ca68 264 PRINTS PR01805 VacJ lipoprotein signature 53 69 1.5E-22 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 THITH_14730 a0032461f7f9059ddc60a7b353c4ca68 264 PRINTS PR01805 VacJ lipoprotein signature 103 120 1.5E-22 T 13-10-2018 IPR007428 MlaA lipoprotein GO:0016020 THITH_06230 67cf0396d7467ca6b46c7f31f873473e 65 Gene3D G3DSA:2.40.50.530 1 65 8.0E-22 T 13-10-2018 THITH_06230 67cf0396d7467ca6b46c7f31f873473e 65 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.851 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THITH_06230 67cf0396d7467ca6b46c7f31f873473e 65 SUPERFAMILY SSF143034 2 63 3.4E-23 T 13-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_06230 67cf0396d7467ca6b46c7f31f873473e 65 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 63 3.1E-26 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THITH_06230 67cf0396d7467ca6b46c7f31f873473e 65 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 13-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_06230 67cf0396d7467ca6b46c7f31f873473e 65 Pfam PF01632 Ribosomal protein L35 2 62 3.7E-25 T 13-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_06230 67cf0396d7467ca6b46c7f31f873473e 65 PRINTS PR00064 Ribosomal protein L35 signature 3 20 3.6E-21 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THITH_06230 67cf0396d7467ca6b46c7f31f873473e 65 PRINTS PR00064 Ribosomal protein L35 signature 21 35 3.6E-21 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THITH_06230 67cf0396d7467ca6b46c7f31f873473e 65 PRINTS PR00064 Ribosomal protein L35 signature 36 54 3.6E-21 T 13-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 THITH_16350 0983f8861999dd87022ad76d74108a37 438 Pfam PF04055 Radical SAM superfamily 143 320 1.5E-29 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THITH_16350 0983f8861999dd87022ad76d74108a37 438 Pfam PF00919 Uncharacterized protein family UPF0004 7 99 1.1E-18 T 13-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 THITH_16350 0983f8861999dd87022ad76d74108a37 438 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 8 434 1.2E-97 T 13-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 THITH_16350 0983f8861999dd87022ad76d74108a37 438 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 141 161 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 THITH_16350 0983f8861999dd87022ad76d74108a37 438 Gene3D G3DSA:3.40.50.12160 7 126 1.6E-26 T 13-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily THITH_16350 0983f8861999dd87022ad76d74108a37 438 SUPERFAMILY SSF102114 117 367 1.02E-49 T 13-10-2018 THITH_16350 0983f8861999dd87022ad76d74108a37 438 Gene3D G3DSA:2.40.50.140 377 437 9.7E-15 T 13-10-2018 THITH_16350 0983f8861999dd87022ad76d74108a37 438 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 6 437 58.349 T 13-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 THITH_16350 0983f8861999dd87022ad76d74108a37 438 Gene3D G3DSA:3.80.30.20 136 376 1.6E-68 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe THITH_16350 0983f8861999dd87022ad76d74108a37 438 Pfam PF01938 TRAM domain 374 436 2.6E-7 T 13-10-2018 IPR002792 TRAM domain THITH_16350 0983f8861999dd87022ad76d74108a37 438 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 7 434 2.2E-162 T 13-10-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 THITH_16350 0983f8861999dd87022ad76d74108a37 438 SMART SM00729 137 362 7.9E-52 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THITH_00745 bac3f64805616c4a77596f5f9d14b4f5 701 Pfam PF13604 AAA domain 190 372 1.0E-30 T 13-10-2018 THITH_00745 bac3f64805616c4a77596f5f9d14b4f5 701 Hamap MF_01487 RecBCD enzyme subunit RecD [recD]. 28 684 49.762 T 13-10-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 THITH_00745 bac3f64805616c4a77596f5f9d14b4f5 701 Gene3D G3DSA:3.40.50.300 412 546 2.9E-17 T 13-10-2018 THITH_00745 bac3f64805616c4a77596f5f9d14b4f5 701 Gene3D G3DSA:3.40.50.300 551 675 5.2E-25 T 13-10-2018 THITH_00745 bac3f64805616c4a77596f5f9d14b4f5 701 SUPERFAMILY SSF52540 327 668 1.42E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00745 bac3f64805616c4a77596f5f9d14b4f5 701 Gene3D G3DSA:1.10.10.1020 14 138 1.8E-24 T 13-10-2018 THITH_00745 bac3f64805616c4a77596f5f9d14b4f5 701 TIGRFAM TIGR01447 recD: exodeoxyribonuclease V, alpha subunit 19 683 2.3E-170 T 13-10-2018 IPR006344 RecBCD enzyme subunit RecD GO:0004386|GO:0006302|GO:0006310|GO:0008854|GO:0009338 THITH_00745 bac3f64805616c4a77596f5f9d14b4f5 701 Gene3D G3DSA:3.40.50.300 139 402 4.0E-66 T 13-10-2018 THITH_00745 bac3f64805616c4a77596f5f9d14b4f5 701 SUPERFAMILY SSF52540 14 407 1.26E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00745 bac3f64805616c4a77596f5f9d14b4f5 701 Pfam PF13538 UvrD-like helicase C-terminal domain 614 660 1.1E-15 T 13-10-2018 IPR027785 UvrD-like helicase C-terminal domain THITH_08975 e00ed943d59b5e2ca3b4162681192b96 321 Pfam PF01207 Dihydrouridine synthase (Dus) 1 292 2.8E-75 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 THITH_08975 e00ed943d59b5e2ca3b4162681192b96 321 SUPERFAMILY SSF51395 1 288 1.76E-64 T 13-10-2018 THITH_08975 e00ed943d59b5e2ca3b4162681192b96 321 TIGRFAM TIGR00742 yjbN: tRNA dihydrouridine synthase A 1 304 2.2E-120 T 13-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 THITH_08975 e00ed943d59b5e2ca3b4162681192b96 321 Gene3D G3DSA:1.20.120.1460 235 302 5.6E-14 T 13-10-2018 THITH_08975 e00ed943d59b5e2ca3b4162681192b96 321 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 77 95 - T 13-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 THITH_08975 e00ed943d59b5e2ca3b4162681192b96 321 Hamap MF_02041 tRNA-dihydrouridine(20/20a) synthase [dusA]. 1 310 44.206 T 13-10-2018 IPR004653 tRNA-dihydrouridine(20/20a) synthase GO:0002943|GO:0017150 THITH_08975 e00ed943d59b5e2ca3b4162681192b96 321 Gene3D G3DSA:3.20.20.70 1 234 1.8E-67 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_08975 e00ed943d59b5e2ca3b4162681192b96 321 PIRSF PIRSF006621 1 307 8.1E-68 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 THITH_13340 15bbe52782c210f6da755d1b567e9eb0 160 Pfam PF04234 CopC domain 31 150 6.5E-15 T 13-10-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 THITH_13340 15bbe52782c210f6da755d1b567e9eb0 160 Gene3D G3DSA:2.60.40.1220 31 152 1.4E-15 T 13-10-2018 THITH_13340 15bbe52782c210f6da755d1b567e9eb0 160 SUPERFAMILY SSF81296 30 150 1.19E-9 T 13-10-2018 IPR014756 Immunoglobulin E-set THITH_09540 b73f5efadadcc2e1bd9618fe18b9f331 228 SUPERFAMILY SSF46785 14 90 3.61E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_09540 b73f5efadadcc2e1bd9618fe18b9f331 228 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 18 181 3.3E-35 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 THITH_09540 b73f5efadadcc2e1bd9618fe18b9f331 228 Pfam PF04079 Segregation and condensation complex subunit ScpB 21 180 2.1E-54 T 13-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 THITH_09540 b73f5efadadcc2e1bd9618fe18b9f331 228 Gene3D G3DSA:1.10.10.10 13 92 2.0E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_09540 b73f5efadadcc2e1bd9618fe18b9f331 228 SUPERFAMILY SSF46785 96 171 8.16E-25 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_09540 b73f5efadadcc2e1bd9618fe18b9f331 228 Gene3D G3DSA:1.10.10.10 93 189 4.7E-36 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_14070 236fc8ef274aac3baab671d41968887a 849 Gene3D G3DSA:3.40.50.2000 44 829 0.0 T 13-10-2018 THITH_14070 236fc8ef274aac3baab671d41968887a 849 SUPERFAMILY SSF53756 21 833 0.0 T 13-10-2018 THITH_14070 236fc8ef274aac3baab671d41968887a 849 Gene3D G3DSA:3.40.50.2000 486 812 0.0 T 13-10-2018 THITH_14070 236fc8ef274aac3baab671d41968887a 849 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 28 827 0.0 T 13-10-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THITH_14070 236fc8ef274aac3baab671d41968887a 849 Pfam PF00343 Carbohydrate phosphorylase 117 827 0.0 T 13-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THITH_14070 236fc8ef274aac3baab671d41968887a 849 PIRSF PIRSF000460 11 846 1.0E-230 T 13-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THITH_14070 236fc8ef274aac3baab671d41968887a 849 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 672 684 - T 13-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 SUPERFAMILY SSF52200 146 257 7.32E-10 T 13-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily THITH_08235 add4b142c200035eab1262c7d51065e6 1275 Pfam PF00805 Pentapeptide repeats (8 copies) 843 876 7.0E-7 T 13-10-2018 IPR001646 Pentapeptide repeat THITH_08235 add4b142c200035eab1262c7d51065e6 1275 Pfam PF00805 Pentapeptide repeats (8 copies) 887 912 0.0017 T 13-10-2018 IPR001646 Pentapeptide repeat THITH_08235 add4b142c200035eab1262c7d51065e6 1275 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1018 1032 - T 13-10-2018 IPR019775 WD40 repeat, conserved site THITH_08235 add4b142c200035eab1262c7d51065e6 1275 PRINTS PR00320 G protein beta WD-40 repeat signature 1060 1074 9.6E-7 T 13-10-2018 IPR020472 G-protein beta WD-40 repeat THITH_08235 add4b142c200035eab1262c7d51065e6 1275 PRINTS PR00320 G protein beta WD-40 repeat signature 976 990 9.6E-7 T 13-10-2018 IPR020472 G-protein beta WD-40 repeat THITH_08235 add4b142c200035eab1262c7d51065e6 1275 PRINTS PR00320 G protein beta WD-40 repeat signature 1018 1032 9.6E-7 T 13-10-2018 IPR020472 G-protein beta WD-40 repeat THITH_08235 add4b142c200035eab1262c7d51065e6 1275 SUPERFAMILY SSF50978 966 1192 2.93E-82 T 13-10-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 Gene3D G3DSA:3.40.50.10140 151 301 1.9E-11 T 13-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily THITH_08235 add4b142c200035eab1262c7d51065e6 1275 Pfam PF13676 TIR domain 154 255 1.3E-11 T 13-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1060 1074 - T 13-10-2018 IPR019775 WD40 repeat, conserved site THITH_08235 add4b142c200035eab1262c7d51065e6 1275 Pfam PF00400 WD domain, G-beta repeat 1161 1191 1.0E-5 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 Pfam PF00400 WD domain, G-beta repeat 993 1031 1.4E-8 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 Pfam PF00400 WD domain, G-beta repeat 1035 1073 1.4E-7 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 Pfam PF00400 WD domain, G-beta repeat 1119 1157 3.4E-12 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 Pfam PF00400 WD domain, G-beta repeat 1077 1115 1.8E-7 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 Pfam PF00400 WD domain, G-beta repeat 966 989 1.3E-4 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 Gene3D G3DSA:2.160.20.100 809 928 2.4E-17 T 13-10-2018 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 SUPERFAMILY SSF141571 818 923 5.1E-17 T 13-10-2018 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 Pfam PF05729 NACHT domain 402 580 6.6E-9 T 13-10-2018 IPR007111 NACHT nucleoside triphosphatase THITH_08235 add4b142c200035eab1262c7d51065e6 1275 Gene3D G3DSA:2.130.10.10 1121 1195 5.4E-28 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 Gene3D G3DSA:2.130.10.10 929 1120 4.1E-65 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1144 1158 - T 13-10-2018 IPR019775 WD40 repeat, conserved site THITH_08235 add4b142c200035eab1262c7d51065e6 1275 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 976 990 - T 13-10-2018 IPR019775 WD40 repeat, conserved site THITH_08235 add4b142c200035eab1262c7d51065e6 1275 SMART SM00320 1034 1073 3.2E-11 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 SMART SM00320 1076 1115 1.5E-10 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 SMART SM00320 1160 1199 0.0035 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 SMART SM00320 992 1031 1.1E-11 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 SMART SM00320 1118 1157 2.5E-12 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08235 add4b142c200035eab1262c7d51065e6 1275 SMART SM00320 952 989 2.2E-4 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08725 2c8f74e6ef2f6f6ef1099017f09dca1b 273 SUPERFAMILY SSF56752 5 246 5.36E-45 T 13-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 THITH_08725 2c8f74e6ef2f6f6ef1099017f09dca1b 273 Gene3D G3DSA:3.30.470.10 3 108 1.5E-25 T 13-10-2018 THITH_08725 2c8f74e6ef2f6f6ef1099017f09dca1b 273 Pfam PF01063 Amino-transferase class IV 25 240 7.1E-28 T 13-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 THITH_08725 2c8f74e6ef2f6f6ef1099017f09dca1b 273 Gene3D G3DSA:3.20.10.10 112 259 6.8E-33 T 13-10-2018 THITH_02895 43199cb106c643dc496bdd34e944a472 198 SUPERFAMILY SSF50249 1 63 2.06E-16 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_02895 43199cb106c643dc496bdd34e944a472 198 Pfam PF14520 Helix-hairpin-helix domain 72 130 2.4E-14 T 13-10-2018 THITH_02895 43199cb106c643dc496bdd34e944a472 198 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 196 29.524 T 13-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 THITH_02895 43199cb106c643dc496bdd34e944a472 198 SMART SM00278 73 92 19.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THITH_02895 43199cb106c643dc496bdd34e944a472 198 SMART SM00278 108 127 0.11 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THITH_02895 43199cb106c643dc496bdd34e944a472 198 Gene3D G3DSA:1.10.8.10 151 196 1.1E-8 T 13-10-2018 THITH_02895 43199cb106c643dc496bdd34e944a472 198 Gene3D G3DSA:1.10.150.20 67 137 2.7E-22 T 13-10-2018 THITH_02895 43199cb106c643dc496bdd34e944a472 198 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 195 6.1E-46 T 13-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 THITH_02895 43199cb106c643dc496bdd34e944a472 198 SUPERFAMILY SSF46929 152 194 1.23E-6 T 13-10-2018 IPR036267 RuvA, C-terminal domain superfamily THITH_02895 43199cb106c643dc496bdd34e944a472 198 Pfam PF01330 RuvA N terminal domain 1 62 2.1E-19 T 13-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 THITH_02895 43199cb106c643dc496bdd34e944a472 198 Gene3D G3DSA:2.40.50.140 1 65 4.8E-25 T 13-10-2018 THITH_02895 43199cb106c643dc496bdd34e944a472 198 SUPERFAMILY SSF47781 66 134 1.96E-18 T 13-10-2018 IPR010994 RuvA domain 2-like THITH_02895 43199cb106c643dc496bdd34e944a472 198 Pfam PF07499 RuvA, C-terminal domain 154 194 3.7E-9 T 13-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 THITH_02495 aeff64ca4fd169ce094fc0a904d8f6de 478 Gene3D G3DSA:1.10.10.410 415 477 8.4E-28 T 13-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal THITH_02495 aeff64ca4fd169ce094fc0a904d8f6de 478 Pfam PF02934 GatB/GatE catalytic domain 5 288 4.3E-113 T 13-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 THITH_02495 aeff64ca4fd169ce094fc0a904d8f6de 478 SUPERFAMILY SSF55931 4 296 3.99E-120 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 THITH_02495 aeff64ca4fd169ce094fc0a904d8f6de 478 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 475 5.6E-179 T 13-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 THITH_02495 aeff64ca4fd169ce094fc0a904d8f6de 478 Gene3D G3DSA:1.10.150.380 300 413 1.4E-36 T 13-10-2018 THITH_02495 aeff64ca4fd169ce094fc0a904d8f6de 478 SMART SM00845 328 475 1.3E-87 T 13-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 THITH_02495 aeff64ca4fd169ce094fc0a904d8f6de 478 Pfam PF02637 GatB domain 328 475 8.5E-57 T 13-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 THITH_02495 aeff64ca4fd169ce094fc0a904d8f6de 478 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 476 39.555 T 13-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 THITH_02495 aeff64ca4fd169ce094fc0a904d8f6de 478 SUPERFAMILY SSF89095 297 402 1.02E-36 T 13-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 THITH_02495 aeff64ca4fd169ce094fc0a904d8f6de 478 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 144 158 - T 13-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 THITH_11415 2510c19146b82d386d5eef772ef455f6 391 ProSitePatterns PS01304 ubiH/COQ6 monooxygenase family signature. 296 309 - T 13-10-2018 IPR018168 Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site GO:0016709|GO:0055114 Reactome: R-HSA-2142789 THITH_11415 2510c19146b82d386d5eef772ef455f6 391 Pfam PF01494 FAD binding domain 8 344 8.1E-38 T 13-10-2018 IPR002938 FAD-binding domain GO:0071949 THITH_11415 2510c19146b82d386d5eef772ef455f6 391 Gene3D G3DSA:3.50.50.60 9 338 2.6E-101 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_11415 2510c19146b82d386d5eef772ef455f6 391 SUPERFAMILY SSF51905 7 384 3.16E-58 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_11415 2510c19146b82d386d5eef772ef455f6 391 Gene3D G3DSA:3.30.9.50 83 271 2.6E-101 T 13-10-2018 THITH_11415 2510c19146b82d386d5eef772ef455f6 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 313 7.6E-19 T 13-10-2018 THITH_11415 2510c19146b82d386d5eef772ef455f6 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 7.6E-19 T 13-10-2018 THITH_11415 2510c19146b82d386d5eef772ef455f6 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 282 297 7.6E-19 T 13-10-2018 THITH_11415 2510c19146b82d386d5eef772ef455f6 391 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 158 173 7.6E-19 T 13-10-2018 THITH_11415 2510c19146b82d386d5eef772ef455f6 391 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 9 390 2.3E-115 T 13-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 THITH_08125 cafdf1ac381bc8f769497f948569c507 465 Pfam PF09459 Ethylbenzene dehydrogenase 43 349 7.0E-44 T 13-10-2018 IPR019020 Cytochrome c-552/DMSO reductase-like, haem-binding domain GO:0020037 THITH_09430 1419703a515f0065bbde365aced86e43 233 Gene3D G3DSA:3.10.20.30 1 102 8.4E-31 T 13-10-2018 IPR012675 Beta-grasp domain superfamily THITH_09430 1419703a515f0065bbde365aced86e43 233 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 3 107 6.5E-28 T 13-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_09430 1419703a515f0065bbde365aced86e43 233 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 144 155 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_09430 1419703a515f0065bbde365aced86e43 233 SUPERFAMILY SSF46548 103 231 9.42E-38 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_09430 1419703a515f0065bbde365aced86e43 233 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 5 225 2.9E-77 T 13-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_09430 1419703a515f0065bbde365aced86e43 233 Gene3D G3DSA:1.10.1060.10 103 233 1.2E-56 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_09430 1419703a515f0065bbde365aced86e43 233 SUPERFAMILY SSF54292 2 102 3.1E-25 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 THITH_09430 1419703a515f0065bbde365aced86e43 233 Pfam PF13183 4Fe-4S dicluster domain 141 214 1.9E-11 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_13080 d3eb0f0f912c19edbb0be6eddb6080c7 298 Hamap MF_02125 50S ribosomal protein L3 glutamine methyltransferase [prmB]. 1 296 49.759 T 13-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 THITH_13080 d3eb0f0f912c19edbb0be6eddb6080c7 298 SUPERFAMILY SSF53335 10 289 7.37E-52 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_13080 d3eb0f0f912c19edbb0be6eddb6080c7 298 Gene3D G3DSA:1.10.8.10 10 99 2.9E-7 T 13-10-2018 THITH_13080 d3eb0f0f912c19edbb0be6eddb6080c7 298 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 39 266 2.9E-60 T 13-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 THITH_13080 d3eb0f0f912c19edbb0be6eddb6080c7 298 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 200 206 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THITH_13080 d3eb0f0f912c19edbb0be6eddb6080c7 298 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 9 288 3.7E-72 T 13-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 THITH_13080 d3eb0f0f912c19edbb0be6eddb6080c7 298 Gene3D G3DSA:3.40.50.150 100 271 3.9E-47 T 13-10-2018 THITH_13080 d3eb0f0f912c19edbb0be6eddb6080c7 298 Pfam PF05175 Methyltransferase small domain 124 211 4.6E-17 T 13-10-2018 IPR007848 Methyltransferase small domain GO:0008168 THITH_13080 d3eb0f0f912c19edbb0be6eddb6080c7 298 PIRSF PIRSF037167 1 298 2.0E-123 T 13-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 THITH_13080 d3eb0f0f912c19edbb0be6eddb6080c7 298 TIGRFAM TIGR03533 L3_gln_methyl: protein-(glutamine-N5) methyltransferase, ribosomal protein L3-specific 7 290 4.5E-121 T 13-10-2018 IPR017127 Ribosomal protein L3-specific, glutamine-N5-methyltransferase GO:0005622|GO:0009007|GO:0032775 THITH_00465 8e944d43de442102c6e8cf36050d0b33 244 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 3 236 2.7E-81 T 13-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 THITH_00465 8e944d43de442102c6e8cf36050d0b33 244 SUPERFAMILY SSF51366 1 238 4.0E-75 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 THITH_00465 8e944d43de442102c6e8cf36050d0b33 244 Pfam PF00977 Histidine biosynthesis protein 3 232 3.8E-79 T 13-10-2018 IPR006062 Histidine biosynthesis GO:0000105 THITH_00465 8e944d43de442102c6e8cf36050d0b33 244 Gene3D G3DSA:3.20.20.70 1 240 4.2E-90 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_00465 8e944d43de442102c6e8cf36050d0b33 244 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 2 239 36.852 T 13-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 THITH_02885 23fb0ed47a61227697278129c4e8751f 246 Gene3D G3DSA:1.10.10.200 1 80 2.8E-33 T 13-10-2018 IPR017856 Integrase-like, N-terminal THITH_02885 23fb0ed47a61227697278129c4e8751f 246 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 237 1.1E-98 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_02885 23fb0ed47a61227697278129c4e8751f 246 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 239 36.472 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_02885 23fb0ed47a61227697278129c4e8751f 246 Pfam PF01709 Transcriptional regulator 5 237 3.3E-94 T 13-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_02885 23fb0ed47a61227697278129c4e8751f 246 Gene3D G3DSA:3.30.70.980 85 236 1.7E-54 T 13-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_02885 23fb0ed47a61227697278129c4e8751f 246 SUPERFAMILY SSF75625 3 243 1.96E-95 T 13-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_02885 23fb0ed47a61227697278129c4e8751f 246 Gene3D G3DSA:3.30.70.980 130 205 1.7E-54 T 13-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_00915 bb874f5e8cf23930e17673173c0c336f 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 72 94 - T 13-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_00915 bb874f5e8cf23930e17673173c0c336f 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 1.1E-41 T 13-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_00915 bb874f5e8cf23930e17673173c0c336f 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 103 27.981 T 13-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_00915 bb874f5e8cf23930e17673173c0c336f 103 SUPERFAMILY SSF141091 1 101 4.97E-40 T 13-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_00915 bb874f5e8cf23930e17673173c0c336f 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 101 1.1E-42 T 13-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_13085 a233e9e4738fa02aa9e7c8b901a017b6 804 Gene3D G3DSA:3.20.20.450 541 801 8.6E-58 T 13-10-2018 IPR035919 EAL domain superfamily THITH_13085 a233e9e4738fa02aa9e7c8b901a017b6 804 SUPERFAMILY SSF55073 400 539 6.2E-11 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_13085 a233e9e4738fa02aa9e7c8b901a017b6 804 Pfam PF00563 EAL domain 559 792 1.4E-51 T 13-10-2018 IPR001633 EAL domain THITH_13085 a233e9e4738fa02aa9e7c8b901a017b6 804 Gene3D G3DSA:3.30.70.270 397 540 1.9E-10 T 13-10-2018 THITH_13085 a233e9e4738fa02aa9e7c8b901a017b6 804 SUPERFAMILY SSF141868 558 793 7.72E-52 T 13-10-2018 IPR035919 EAL domain superfamily THITH_13085 a233e9e4738fa02aa9e7c8b901a017b6 804 SUPERFAMILY SSF52172 43 153 5.68E-7 T 13-10-2018 IPR011006 CheY-like superfamily THITH_13085 a233e9e4738fa02aa9e7c8b901a017b6 804 SUPERFAMILY SSF55785 137 252 7.33E-5 T 13-10-2018 IPR035965 PAS domain superfamily THITH_13085 a233e9e4738fa02aa9e7c8b901a017b6 804 Gene3D G3DSA:3.30.450.20 137 260 3.9E-5 T 13-10-2018 THITH_13085 a233e9e4738fa02aa9e7c8b901a017b6 804 Pfam PF00990 Diguanylate cyclase, GGDEF domain 443 534 1.6E-4 T 13-10-2018 IPR000160 GGDEF domain THITH_13085 a233e9e4738fa02aa9e7c8b901a017b6 804 SMART SM00267 385 540 0.0021 T 13-10-2018 IPR000160 GGDEF domain THITH_13085 a233e9e4738fa02aa9e7c8b901a017b6 804 SMART SM00052 552 797 2.3E-33 T 13-10-2018 IPR001633 EAL domain THITH_14460 d32654410757d4562560920d67e35453 474 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 16 464 3.8E-162 T 13-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_14460 d32654410757d4562560920d67e35453 474 Pfam PF08245 Mur ligase middle domain 119 299 4.1E-28 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 THITH_14460 d32654410757d4562560920d67e35453 474 Gene3D G3DSA:3.40.50.720 15 102 1.3E-29 T 13-10-2018 THITH_14460 d32654410757d4562560920d67e35453 474 SUPERFAMILY SSF53623 100 316 7.98E-72 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THITH_14460 d32654410757d4562560920d67e35453 474 SUPERFAMILY SSF53244 318 465 1.1E-44 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THITH_14460 d32654410757d4562560920d67e35453 474 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 14 470 42.288 T 13-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_14460 d32654410757d4562560920d67e35453 474 Gene3D G3DSA:3.90.190.20 317 469 1.8E-47 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THITH_14460 d32654410757d4562560920d67e35453 474 Pfam PF01225 Mur ligase family, catalytic domain 16 113 4.9E-24 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 THITH_14460 d32654410757d4562560920d67e35453 474 Gene3D G3DSA:3.40.1190.10 103 316 6.2E-81 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THITH_14460 d32654410757d4562560920d67e35453 474 SUPERFAMILY SSF51984 15 101 2.75E-27 T 13-10-2018 THITH_14460 d32654410757d4562560920d67e35453 474 Pfam PF02875 Mur ligase family, glutamate ligase domain 321 405 1.5E-19 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 THITH_06535 f4195fc1837ac4d225a8aad831e63806 324 Gene3D G3DSA:2.40.440.10 39 313 3.0E-86 T 13-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like THITH_06535 f4195fc1837ac4d225a8aad831e63806 324 Pfam PF03734 L,D-transpeptidase catalytic domain 109 241 9.4E-23 T 13-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 THITH_06535 f4195fc1837ac4d225a8aad831e63806 324 SUPERFAMILY SSF141523 107 241 2.88E-34 T 13-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 SMART SM00091 6 72 1.7E-7 T 13-10-2018 IPR000014 PAS domain THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 SMART SM00091 135 206 4.1 T 13-10-2018 IPR000014 PAS domain THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 SUPERFAMILY SSF55785 125 256 2.66E-11 T 13-10-2018 IPR035965 PAS domain superfamily THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 Gene3D G3DSA:3.30.450.20 119 271 2.3E-17 T 13-10-2018 THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 396 500 1.5E-18 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 Pfam PF08448 PAS fold 141 260 2.8E-11 T 13-10-2018 IPR013656 PAS fold-4 THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 Pfam PF08448 PAS fold 12 72 1.2E-6 T 13-10-2018 IPR013656 PAS fold-4 THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 SMART SM00387 392 502 5.9E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 5 68 1.4E-5 T 13-10-2018 IPR000014 PAS domain THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 Gene3D G3DSA:3.30.565.10 349 504 5.5E-39 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 Gene3D G3DSA:3.30.450.20 1 116 3.6E-10 T 13-10-2018 THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 Gene3D G3DSA:1.10.287.130 285 348 1.4E-9 T 13-10-2018 THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 447 4.3E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 486 499 4.3E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 461 4.3E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 480 4.3E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 SUPERFAMILY SSF55874 337 503 3.01E-40 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_09125 27f5b1b769ba4d278f8fc49fce5175c5 507 SUPERFAMILY SSF55785 6 72 2.09E-11 T 13-10-2018 IPR035965 PAS domain superfamily THITH_01910 b6d3f1092f2b806e378a71f30df42ffd 519 Pfam PF02384 N-6 DNA Methylase 171 485 2.9E-102 T 13-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THITH_01910 b6d3f1092f2b806e378a71f30df42ffd 519 SUPERFAMILY SSF53335 8 518 1.52E-134 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_01910 b6d3f1092f2b806e378a71f30df42ffd 519 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 297 303 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THITH_01910 b6d3f1092f2b806e378a71f30df42ffd 519 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 195 211 1.2E-14 T 13-10-2018 THITH_01910 b6d3f1092f2b806e378a71f30df42ffd 519 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 219 233 1.2E-14 T 13-10-2018 THITH_01910 b6d3f1092f2b806e378a71f30df42ffd 519 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 294 306 1.2E-14 T 13-10-2018 THITH_01910 b6d3f1092f2b806e378a71f30df42ffd 519 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 331 355 1.2E-14 T 13-10-2018 THITH_01910 b6d3f1092f2b806e378a71f30df42ffd 519 Gene3D G3DSA:3.40.50.150 193 479 7.1E-81 T 13-10-2018 THITH_01910 b6d3f1092f2b806e378a71f30df42ffd 519 Pfam PF12161 HsdM N-terminal domain 11 157 4.1E-24 T 13-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THITH_01910 b6d3f1092f2b806e378a71f30df42ffd 519 Gene3D G3DSA:1.20.1260.30 2 189 8.4E-34 T 13-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily THITH_01910 b6d3f1092f2b806e378a71f30df42ffd 519 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 8 499 1.2E-82 T 13-10-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 SMART SM00267 723 896 1.6E-62 T 13-10-2018 IPR000160 GGDEF domain THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 Gene3D G3DSA:3.40.190.10 118 228 2.8E-15 T 13-10-2018 THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 Pfam PF00990 Diguanylate cyclase, GGDEF domain 734 892 7.2E-42 T 13-10-2018 IPR000160 GGDEF domain THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 SMART SM00086 434 475 0.02 T 13-10-2018 IPR001610 PAC motif THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 SMART SM00086 681 723 2.0E-7 T 13-10-2018 IPR001610 PAC motif THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 SMART SM00086 560 601 3.8E-6 T 13-10-2018 IPR001610 PAC motif THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 614 729 9.7E-18 T 13-10-2018 IPR000014 PAS domain THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 483 608 1.3E-9 T 13-10-2018 IPR000014 PAS domain THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 Gene3D G3DSA:3.30.70.270 731 908 1.1E-54 T 13-10-2018 THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 SUPERFAMILY SSF55785 377 484 1.77E-17 T 13-10-2018 IPR035965 PAS domain superfamily THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 SUPERFAMILY SSF55785 597 717 8.55E-28 T 13-10-2018 IPR035965 PAS domain superfamily THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 Pfam PF08447 PAS fold 511 594 3.1E-12 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 Pfam PF08447 PAS fold 384 462 7.8E-13 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 731 894 2.8E-38 T 13-10-2018 IPR000160 GGDEF domain THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 SUPERFAMILY SSF55073 739 897 3.69E-44 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 SMART SM00052 906 1152 5.7E-116 T 13-10-2018 IPR001633 EAL domain THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 Pfam PF00989 PAS fold 615 719 3.9E-14 T 13-10-2018 IPR013767 PAS fold GO:0006355 THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 SUPERFAMILY SSF53850 46 275 7.35E-13 T 13-10-2018 THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 Gene3D G3DSA:3.30.450.20 357 473 6.4E-21 T 13-10-2018 THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 Gene3D G3DSA:3.30.450.20 606 730 9.2E-31 T 13-10-2018 THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 33 285 6.4E-37 T 13-10-2018 THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 Gene3D G3DSA:3.40.190.10 34 242 2.8E-15 T 13-10-2018 THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 Gene3D G3DSA:3.30.450.20 483 554 8.6E-14 T 13-10-2018 THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 Gene3D G3DSA:2.10.70.100 557 603 3.8E-7 T 13-10-2018 THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 SUPERFAMILY SSF141868 911 1159 1.57E-89 T 13-10-2018 IPR035919 EAL domain superfamily THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 Pfam PF00563 EAL domain 913 1147 1.1E-74 T 13-10-2018 IPR001633 EAL domain THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 SMART SM00091 487 554 110.0 T 13-10-2018 IPR000014 PAS domain THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 SMART SM00091 609 676 1.1E-6 T 13-10-2018 IPR000014 PAS domain THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 SMART SM00091 356 428 1.4 T 13-10-2018 IPR000014 PAS domain THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 Gene3D G3DSA:3.20.20.450 909 1161 2.3E-103 T 13-10-2018 IPR035919 EAL domain superfamily THITH_06650 382b9eb8675842fe16a1296c721e5458 1170 SUPERFAMILY SSF55785 472 599 1.12E-17 T 13-10-2018 IPR035965 PAS domain superfamily THITH_07130 accb35526f1a865d6d40b137bd3a2238 224 Pfam PF00154 recA bacterial DNA recombination protein 22 124 3.5E-7 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THITH_07130 accb35526f1a865d6d40b137bd3a2238 224 SUPERFAMILY SSF52540 45 159 5.69E-28 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_07130 accb35526f1a865d6d40b137bd3a2238 224 PIRSF PIRSF037290 1 221 1.5E-56 T 13-10-2018 IPR017166 Uncharacterised conserved protein UCP037290 THITH_07130 accb35526f1a865d6d40b137bd3a2238 224 Gene3D G3DSA:3.40.50.300 45 158 1.1E-30 T 13-10-2018 THITH_07865 966c0ac6ecc5c1e15964bfe7dd360499 215 Gene3D G3DSA:1.10.150.240 14 80 9.4E-50 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 THITH_07865 966c0ac6ecc5c1e15964bfe7dd360499 215 Pfam PF13419 Haloacid dehalogenase-like hydrolase 2 179 3.8E-30 T 13-10-2018 THITH_07865 966c0ac6ecc5c1e15964bfe7dd360499 215 Gene3D G3DSA:3.40.50.1000 2 200 9.4E-50 T 13-10-2018 IPR023214 HAD superfamily THITH_07865 966c0ac6ecc5c1e15964bfe7dd360499 215 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 65 179 1.8E-9 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_07865 966c0ac6ecc5c1e15964bfe7dd360499 215 SUPERFAMILY SSF56784 1 210 2.43E-55 T 13-10-2018 IPR036412 HAD-like superfamily THITH_07865 966c0ac6ecc5c1e15964bfe7dd360499 215 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 83 174 1.4E-9 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_12775 39b57bb79b19f0fd5d226433b3c3e6cd 132 SUPERFAMILY SSF88723 6 119 1.57E-20 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_12775 39b57bb79b19f0fd5d226433b3c3e6cd 132 Pfam PF01850 PIN domain 6 118 2.8E-18 T 13-10-2018 IPR002716 PIN domain THITH_12775 39b57bb79b19f0fd5d226433b3c3e6cd 132 Gene3D G3DSA:3.40.50.1010 6 124 6.4E-19 T 13-10-2018 THITH_12775 39b57bb79b19f0fd5d226433b3c3e6cd 132 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 127 10.588 T 13-10-2018 IPR022907 VapC family GO:0004540 THITH_04175 ba1710ab8adde22712fe475439a82193 237 Pfam PF00117 Glutamine amidotransferase class-I 53 186 4.5E-17 T 13-10-2018 IPR017926 Glutamine amidotransferase THITH_04175 ba1710ab8adde22712fe475439a82193 237 SUPERFAMILY SSF52317 43 193 1.99E-37 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_04175 ba1710ab8adde22712fe475439a82193 237 Gene3D G3DSA:3.40.50.880 14 236 1.8E-52 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_08805 f5625c5208e1e5a8fc3552fee1f0df00 485 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 95 278 4.5E-18 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THITH_08805 f5625c5208e1e5a8fc3552fee1f0df00 485 Gene3D G3DSA:1.10.530.10 310 481 5.0E-39 T 13-10-2018 THITH_08805 f5625c5208e1e5a8fc3552fee1f0df00 485 SUPERFAMILY SSF53955 311 468 9.38E-37 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily THITH_08805 f5625c5208e1e5a8fc3552fee1f0df00 485 Gene3D G3DSA:3.40.190.10 146 250 2.8E-46 T 13-10-2018 THITH_08805 f5625c5208e1e5a8fc3552fee1f0df00 485 Pfam PF01464 Transglycosylase SLT domain 315 426 6.3E-19 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 THITH_08805 f5625c5208e1e5a8fc3552fee1f0df00 485 Gene3D G3DSA:3.40.190.10 48 282 2.8E-46 T 13-10-2018 THITH_08805 f5625c5208e1e5a8fc3552fee1f0df00 485 SMART SM00062 52 294 6.0E-4 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THITH_08805 f5625c5208e1e5a8fc3552fee1f0df00 485 SUPERFAMILY SSF53850 53 293 1.66E-28 T 13-10-2018 THITH_05310 40c821562e7abf9e4d76ccd64b974678 453 SUPERFAMILY SSF161093 281 450 6.15E-46 T 13-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 THITH_05310 40c821562e7abf9e4d76ccd64b974678 453 Pfam PF03448 MgtE intracellular N domain 36 135 7.8E-24 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain THITH_05310 40c821562e7abf9e4d76ccd64b974678 453 SMART SM00116 144 197 7.5 T 13-10-2018 IPR000644 CBS domain THITH_05310 40c821562e7abf9e4d76ccd64b974678 453 SMART SM00116 208 256 2.7E-6 T 13-10-2018 IPR000644 CBS domain THITH_05310 40c821562e7abf9e4d76ccd64b974678 453 TIGRFAM TIGR00400 mgtE: magnesium transporter 16 451 6.7E-118 T 13-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 THITH_05310 40c821562e7abf9e4d76ccd64b974678 453 Pfam PF00571 CBS domain 137 193 3.3E-6 T 13-10-2018 IPR000644 CBS domain THITH_05310 40c821562e7abf9e4d76ccd64b974678 453 Pfam PF00571 CBS domain 206 255 3.3E-7 T 13-10-2018 IPR000644 CBS domain THITH_05310 40c821562e7abf9e4d76ccd64b974678 453 Gene3D G3DSA:3.10.580.10 133 261 2.0E-42 T 13-10-2018 THITH_05310 40c821562e7abf9e4d76ccd64b974678 453 SMART SM00924 34 137 1.2E-25 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain THITH_05310 40c821562e7abf9e4d76ccd64b974678 453 SUPERFAMILY SSF54631 137 270 1.11E-32 T 13-10-2018 THITH_05310 40c821562e7abf9e4d76ccd64b974678 453 SUPERFAMILY SSF158791 11 134 6.41E-27 T 13-10-2018 THITH_05310 40c821562e7abf9e4d76ccd64b974678 453 Gene3D G3DSA:1.25.60.10 6 132 1.5E-20 T 13-10-2018 IPR038076 MgtE, N-terminal domain superfamily THITH_05310 40c821562e7abf9e4d76ccd64b974678 453 Gene3D G3DSA:1.10.357.20 276 451 3.9E-52 T 13-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain THITH_05310 40c821562e7abf9e4d76ccd64b974678 453 Pfam PF01769 Divalent cation transporter 323 443 3.5E-25 T 13-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 THITH_14215 b0f6bef1e25f38959f73a6cfdfede2f0 176 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 175 36.477 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THITH_14215 b0f6bef1e25f38959f73a6cfdfede2f0 176 SUPERFAMILY SSF56053 1 81 4.08E-19 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14215 b0f6bef1e25f38959f73a6cfdfede2f0 176 PIRSF PIRSF002162 1 176 1.7E-45 T 13-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14215 b0f6bef1e25f38959f73a6cfdfede2f0 176 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 153 161 - T 13-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14215 b0f6bef1e25f38959f73a6cfdfede2f0 176 Gene3D G3DSA:3.90.930.12 82 176 1.1E-39 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14215 b0f6bef1e25f38959f73a6cfdfede2f0 176 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 175 2.3E-70 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THITH_14215 b0f6bef1e25f38959f73a6cfdfede2f0 176 SUPERFAMILY SSF56053 82 176 6.41E-37 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14215 b0f6bef1e25f38959f73a6cfdfede2f0 176 PRINTS PR00059 Ribosomal protein L6 signature 140 161 1.1E-33 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THITH_14215 b0f6bef1e25f38959f73a6cfdfede2f0 176 PRINTS PR00059 Ribosomal protein L6 signature 98 114 1.1E-33 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THITH_14215 b0f6bef1e25f38959f73a6cfdfede2f0 176 PRINTS PR00059 Ribosomal protein L6 signature 70 95 1.1E-33 T 13-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 THITH_14215 b0f6bef1e25f38959f73a6cfdfede2f0 176 Pfam PF00347 Ribosomal protein L6 12 81 4.4E-14 T 13-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14215 b0f6bef1e25f38959f73a6cfdfede2f0 176 Pfam PF00347 Ribosomal protein L6 89 163 5.4E-21 T 13-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14215 b0f6bef1e25f38959f73a6cfdfede2f0 176 Gene3D G3DSA:3.90.930.12 1 81 5.4E-23 T 13-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14210 555904a0078ae4c46894cd79413ed165 117 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 2 117 26.062 T 13-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14210 555904a0078ae4c46894cd79413ed165 117 SUPERFAMILY SSF53137 3 115 3.71E-52 T 13-10-2018 THITH_14210 555904a0078ae4c46894cd79413ed165 117 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 3 117 2.3E-40 T 13-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14210 555904a0078ae4c46894cd79413ed165 117 Gene3D G3DSA:3.30.420.100 1 117 5.7E-42 T 13-10-2018 THITH_14210 555904a0078ae4c46894cd79413ed165 117 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 2 117 5.8E-40 T 13-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_13095 467f4c01854be8a2b8cd0a8401a84ad1 321 SUPERFAMILY SSF55681 11 319 2.3E-65 T 13-10-2018 THITH_13095 467f4c01854be8a2b8cd0a8401a84ad1 321 Pfam PF00152 tRNA synthetases class II (D, K and N) 204 317 4.3E-15 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_13095 467f4c01854be8a2b8cd0a8401a84ad1 321 Gene3D G3DSA:3.30.930.10 7 321 2.6E-82 T 13-10-2018 THITH_13095 467f4c01854be8a2b8cd0a8401a84ad1 321 Pfam PF00152 tRNA synthetases class II (D, K and N) 14 131 1.3E-16 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_13095 467f4c01854be8a2b8cd0a8401a84ad1 321 TIGRFAM TIGR00462 genX: EF-P lysine aminoacylase GenX 13 316 1.2E-101 T 13-10-2018 IPR004525 Elongation factor P--(R)-beta-lysine ligase GO:0004824|GO:0005524|GO:0005737|GO:0006430 THITH_13095 467f4c01854be8a2b8cd0a8401a84ad1 321 PRINTS PR00982 Lysyl-tRNA synthetase signature 89 106 2.9E-12 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THITH_13095 467f4c01854be8a2b8cd0a8401a84ad1 321 PRINTS PR00982 Lysyl-tRNA synthetase signature 204 220 2.9E-12 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THITH_13095 467f4c01854be8a2b8cd0a8401a84ad1 321 PRINTS PR00982 Lysyl-tRNA synthetase signature 71 84 2.9E-12 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THITH_13095 467f4c01854be8a2b8cd0a8401a84ad1 321 PRINTS PR00982 Lysyl-tRNA synthetase signature 26 36 2.9E-12 T 13-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THITH_14770 a365343fa9a03af3fa6257471fc92758 198 Gene3D G3DSA:3.40.50.1470 2 191 2.2E-66 T 13-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 THITH_14770 a365343fa9a03af3fa6257471fc92758 198 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 3 180 35.316 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 THITH_14770 a365343fa9a03af3fa6257471fc92758 198 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 16 29 - T 13-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 THITH_14770 a365343fa9a03af3fa6257471fc92758 198 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 110 120 - T 13-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 THITH_14770 a365343fa9a03af3fa6257471fc92758 198 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 4 187 1.4E-60 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 THITH_14770 a365343fa9a03af3fa6257471fc92758 198 SUPERFAMILY SSF53178 3 187 3.92E-65 T 13-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 THITH_14770 a365343fa9a03af3fa6257471fc92758 198 Pfam PF01195 Peptidyl-tRNA hydrolase 5 185 4.5E-54 T 13-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 THITH_12240 6a42985488adc3556472eb27321cf13a 463 SUPERFAMILY SSF51905 1 364 3.74E-57 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_12240 6a42985488adc3556472eb27321cf13a 463 Gene3D G3DSA:3.30.390.30 337 459 1.9E-41 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THITH_12240 6a42985488adc3556472eb27321cf13a 463 SUPERFAMILY SSF55424 334 449 2.75E-33 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THITH_12240 6a42985488adc3556472eb27321cf13a 463 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 338 447 6.0E-32 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THITH_12240 6a42985488adc3556472eb27321cf13a 463 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 38 48 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 THITH_12240 6a42985488adc3556472eb27321cf13a 463 PIRSF PIRSF000350 1 447 6.2E-68 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 THITH_12240 6a42985488adc3556472eb27321cf13a 463 Gene3D G3DSA:3.50.50.60 142 259 5.1E-110 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_12240 6a42985488adc3556472eb27321cf13a 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 130 148 3.4E-31 T 13-10-2018 THITH_12240 6a42985488adc3556472eb27321cf13a 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 252 268 3.4E-31 T 13-10-2018 THITH_12240 6a42985488adc3556472eb27321cf13a 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 3.4E-31 T 13-10-2018 THITH_12240 6a42985488adc3556472eb27321cf13a 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 281 303 3.4E-31 T 13-10-2018 THITH_12240 6a42985488adc3556472eb27321cf13a 463 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 3.4E-31 T 13-10-2018 THITH_12240 6a42985488adc3556472eb27321cf13a 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 167 192 1.9E-67 T 13-10-2018 THITH_12240 6a42985488adc3556472eb27321cf13a 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 423 443 1.9E-67 T 13-10-2018 THITH_12240 6a42985488adc3556472eb27321cf13a 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.9E-67 T 13-10-2018 THITH_12240 6a42985488adc3556472eb27321cf13a 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 37 52 1.9E-67 T 13-10-2018 THITH_12240 6a42985488adc3556472eb27321cf13a 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 296 303 1.9E-67 T 13-10-2018 THITH_12240 6a42985488adc3556472eb27321cf13a 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 401 416 1.9E-67 T 13-10-2018 THITH_12240 6a42985488adc3556472eb27321cf13a 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 334 355 1.9E-67 T 13-10-2018 THITH_12240 6a42985488adc3556472eb27321cf13a 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 133 142 1.9E-67 T 13-10-2018 THITH_12240 6a42985488adc3556472eb27321cf13a 463 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 253 267 1.9E-67 T 13-10-2018 THITH_12240 6a42985488adc3556472eb27321cf13a 463 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 316 1.2E-64 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THITH_12240 6a42985488adc3556472eb27321cf13a 463 Gene3D G3DSA:3.50.50.60 4 320 5.1E-110 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_01810 9eeda943d9c829e754cc1a377fda610c 784 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 686 704 - T 13-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 THITH_01810 9eeda943d9c829e754cc1a377fda610c 784 SUPERFAMILY SSF56059 1 375 4.36E-102 T 13-10-2018 THITH_01810 9eeda943d9c829e754cc1a377fda610c 784 Gene3D G3DSA:3.50.30.10 365 469 3.7E-39 T 13-10-2018 THITH_01810 9eeda943d9c829e754cc1a377fda610c 784 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 406 417 - T 13-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 THITH_01810 9eeda943d9c829e754cc1a377fda610c 784 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 4 780 0.0 T 13-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 THITH_01810 9eeda943d9c829e754cc1a377fda610c 784 Pfam PF00391 PEP-utilising enzyme, mobile domain 376 447 1.1E-26 T 13-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THITH_01810 9eeda943d9c829e754cc1a377fda610c 784 Gene3D G3DSA:3.30.470.20 189 346 4.1E-53 T 13-10-2018 THITH_01810 9eeda943d9c829e754cc1a377fda610c 784 SUPERFAMILY SSF51621 454 779 5.23E-93 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 THITH_01810 9eeda943d9c829e754cc1a377fda610c 784 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 330 1.6E-113 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 THITH_01810 9eeda943d9c829e754cc1a377fda610c 784 SUPERFAMILY SSF52009 346 459 2.75E-33 T 13-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 THITH_01810 9eeda943d9c829e754cc1a377fda610c 784 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 474 778 4.3E-58 T 13-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 THITH_01810 9eeda943d9c829e754cc1a377fda610c 784 Gene3D G3DSA:3.30.1490.20 1 188 8.1E-70 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 THITH_01810 9eeda943d9c829e754cc1a377fda610c 784 PIRSF PIRSF000854 1 783 0.0 T 13-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 THITH_01810 9eeda943d9c829e754cc1a377fda610c 784 Gene3D G3DSA:3.20.20.60 470 781 2.3E-97 T 13-10-2018 THITH_12950 122e071ae7f268334f08b54342fe041c 162 Pfam PF12838 4Fe-4S dicluster domain 62 115 1.5E-11 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_12950 122e071ae7f268334f08b54342fe041c 162 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 10 159 27.578 T 13-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12950 122e071ae7f268334f08b54342fe041c 162 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 19 140 3.7E-45 T 13-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12950 122e071ae7f268334f08b54342fe041c 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 63 74 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_12950 122e071ae7f268334f08b54342fe041c 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 102 113 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_12950 122e071ae7f268334f08b54342fe041c 162 SUPERFAMILY SSF54862 36 145 4.06E-26 T 13-10-2018 THITH_12950 122e071ae7f268334f08b54342fe041c 162 Gene3D G3DSA:3.30.70.3270 36 162 3.3E-38 T 13-10-2018 THITH_11280 3abc3f5fdb688cf4ff616e5750dc3999 376 Pfam PF02163 Peptidase family M50 140 181 2.6E-7 T 13-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 THITH_11280 3abc3f5fdb688cf4ff616e5750dc3999 376 Gene3D G3DSA:3.10.580.10 237 370 8.5E-18 T 13-10-2018 THITH_11280 3abc3f5fdb688cf4ff616e5750dc3999 376 Pfam PF00571 CBS domain 324 368 1.9E-7 T 13-10-2018 IPR000644 CBS domain THITH_11280 3abc3f5fdb688cf4ff616e5750dc3999 376 Pfam PF00571 CBS domain 249 292 0.0019 T 13-10-2018 IPR000644 CBS domain THITH_11280 3abc3f5fdb688cf4ff616e5750dc3999 376 SMART SM00116 256 304 42.0 T 13-10-2018 IPR000644 CBS domain THITH_11280 3abc3f5fdb688cf4ff616e5750dc3999 376 SMART SM00116 321 368 2.8E-6 T 13-10-2018 IPR000644 CBS domain THITH_11280 3abc3f5fdb688cf4ff616e5750dc3999 376 SUPERFAMILY SSF54631 245 367 2.78E-18 T 13-10-2018 THITH_11280 3abc3f5fdb688cf4ff616e5750dc3999 376 PIRSF PIRSF006404 2 376 2.9E-98 T 13-10-2018 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS THITH_15850 49cfff395e58ae7dca41c564ae1f4c97 268 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 3 262 37.11 T 13-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 THITH_15850 49cfff395e58ae7dca41c564ae1f4c97 268 Hamap MF_00134_A Indole-3-glycerol phosphate synthase [trpC]. 38 258 29.524 T 13-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 THITH_15850 49cfff395e58ae7dca41c564ae1f4c97 268 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 260 2.2E-95 T 13-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 THITH_15850 49cfff395e58ae7dca41c564ae1f4c97 268 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 56 74 - T 13-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 THITH_15850 49cfff395e58ae7dca41c564ae1f4c97 268 Gene3D G3DSA:3.20.20.70 1 264 1.3E-107 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_15850 49cfff395e58ae7dca41c564ae1f4c97 268 SUPERFAMILY SSF51366 12 262 6.95E-90 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 THITH_17005 ff875aebb9cdd5a5df286ce1baa6d3a0 513 Gene3D G3DSA:2.40.30.20 1 93 4.8E-35 T 13-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_17005 ff875aebb9cdd5a5df286ce1baa6d3a0 513 SUPERFAMILY SSF47917 383 511 5.23E-45 T 13-10-2018 THITH_17005 ff875aebb9cdd5a5df286ce1baa6d3a0 513 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 375 1.4E-72 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_17005 ff875aebb9cdd5a5df286ce1baa6d3a0 513 PIRSF PIRSF039088 1 513 8.9E-237 T 13-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17005 ff875aebb9cdd5a5df286ce1baa6d3a0 513 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 512 1.9E-249 T 13-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17005 ff875aebb9cdd5a5df286ce1baa6d3a0 513 SUPERFAMILY SSF50615 10 94 9.42E-30 T 13-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_17005 ff875aebb9cdd5a5df286ce1baa6d3a0 513 Gene3D G3DSA:1.20.150.20 383 513 4.9E-46 T 13-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17005 ff875aebb9cdd5a5df286ce1baa6d3a0 513 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 28 92 1.2E-15 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_17005 ff875aebb9cdd5a5df286ce1baa6d3a0 513 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_17005 ff875aebb9cdd5a5df286ce1baa6d3a0 513 Gene3D G3DSA:3.40.50.300 94 382 6.5E-131 T 13-10-2018 THITH_17005 ff875aebb9cdd5a5df286ce1baa6d3a0 513 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 512 50.894 T 13-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17005 ff875aebb9cdd5a5df286ce1baa6d3a0 513 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 1.6E-43 T 13-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17005 ff875aebb9cdd5a5df286ce1baa6d3a0 513 SUPERFAMILY SSF52540 96 381 2.54E-95 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14175 3c800b8b9617368348722e502fb12d6e 129 SUPERFAMILY SSF53137 14 129 1.05E-47 T 13-10-2018 THITH_14175 3c800b8b9617368348722e502fb12d6e 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 13-10-2018 IPR018102 Ribosomal S11, conserved site THITH_14175 3c800b8b9617368348722e502fb12d6e 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 1.9E-55 T 13-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14175 3c800b8b9617368348722e502fb12d6e 129 Gene3D G3DSA:3.30.420.80 1 129 8.3E-56 T 13-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 THITH_14175 3c800b8b9617368348722e502fb12d6e 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 7 129 32.768 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 THITH_14175 3c800b8b9617368348722e502fb12d6e 129 PIRSF PIRSF002131 1 129 3.3E-52 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 THITH_14175 3c800b8b9617368348722e502fb12d6e 129 Pfam PF00411 Ribosomal protein S11 19 128 2.2E-50 T 13-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 Gene3D G3DSA:3.30.70.870 289 370 1.2E-35 T 13-10-2018 THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 SUPERFAMILY SSF54980 402 496 3.74E-25 T 13-10-2018 IPR035647 EF-G domain III/V-like THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 Hamap MF_00071 Elongation factor 4 [lepA]. 1 600 299.798 T 13-10-2018 IPR006297 Elongation factor 4 GO:0005525 THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 Gene3D G3DSA:2.40.30.10 189 288 1.2E-30 T 13-10-2018 THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 Pfam PF06421 GTP-binding protein LepA C-terminus 490 596 3.2E-49 T 13-10-2018 IPR013842 GTP-binding protein LepA, C-terminal THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 TIGRFAM TIGR01393 lepA: elongation factor 4 7 597 1.0E-296 T 13-10-2018 IPR006297 Elongation factor 4 GO:0005525 THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 Gene3D G3DSA:3.30.70.2570 482 556 1.4E-32 T 13-10-2018 IPR038363 LepA, C-terminal domain superfamily THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 SUPERFAMILY SSF52540 6 208 4.12E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 PRINTS PR00315 GTP-binding elongation factor signature 52 60 4.1E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 PRINTS PR00315 GTP-binding elongation factor signature 77 87 4.1E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 PRINTS PR00315 GTP-binding elongation factor signature 129 138 4.1E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 PRINTS PR00315 GTP-binding elongation factor signature 93 104 4.1E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 PRINTS PR00315 GTP-binding elongation factor signature 9 22 4.1E-14 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 45 60 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 Pfam PF00679 Elongation factor G C-terminus 402 487 1.0E-19 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 Gene3D G3DSA:3.30.70.3380 371 481 5.1E-41 T 13-10-2018 THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 SUPERFAMILY SSF54980 295 373 2.01E-17 T 13-10-2018 IPR035647 EF-G domain III/V-like THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 Pfam PF00009 Elongation factor Tu GTP binding domain 7 184 3.2E-52 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 177 2.0E-18 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 Gene3D G3DSA:3.40.50.300 3 188 1.0E-70 T 13-10-2018 THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 SUPERFAMILY SSF50447 168 291 2.83E-28 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THITH_12150 411f9729010f6f65a40b8c3056a0f969 602 SMART SM00838 401 489 0.0026 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like THITH_02690 fff9e4784e0e76ce6a3c2cfca05419ae 118 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 13-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_02690 fff9e4784e0e76ce6a3c2cfca05419ae 118 SUPERFAMILY SSF50104 2 116 2.81E-48 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily THITH_02690 fff9e4784e0e76ce6a3c2cfca05419ae 118 PRINTS PR00061 Ribosomal protein L19 signature 4 33 4.9E-41 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_02690 fff9e4784e0e76ce6a3c2cfca05419ae 118 PRINTS PR00061 Ribosomal protein L19 signature 34 63 4.9E-41 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_02690 fff9e4784e0e76ce6a3c2cfca05419ae 118 PRINTS PR00061 Ribosomal protein L19 signature 88 113 4.9E-41 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_02690 fff9e4784e0e76ce6a3c2cfca05419ae 118 PIRSF PIRSF002191 1 118 2.9E-51 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_02690 fff9e4784e0e76ce6a3c2cfca05419ae 118 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 31.446 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_02690 fff9e4784e0e76ce6a3c2cfca05419ae 118 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 6.4E-51 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_02690 fff9e4784e0e76ce6a3c2cfca05419ae 118 Gene3D G3DSA:2.30.30.790 2 118 7.8E-17 T 13-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_02690 fff9e4784e0e76ce6a3c2cfca05419ae 118 Pfam PF01245 Ribosomal protein L19 3 112 1.1E-50 T 13-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14655 6979d3d3dfffa5fd2a4841b697b83b33 233 Pfam PF00005 ABC transporter 11 158 5.0E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_14655 6979d3d3dfffa5fd2a4841b697b83b33 233 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 206 228 4.8E-6 T 13-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal THITH_14655 6979d3d3dfffa5fd2a4841b697b83b33 233 TIGRFAM TIGR04406 LPS_export_lptB: LPS export ABC transporter ATP-binding protein 1 233 3.4E-109 T 13-10-2018 IPR030921 LPS export ABC transporter, ATP-binding protein LptB GO:0043190|GO:0055085 THITH_14655 6979d3d3dfffa5fd2a4841b697b83b33 233 SMART SM00382 20 208 7.2E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_14655 6979d3d3dfffa5fd2a4841b697b83b33 233 Gene3D G3DSA:3.40.50.300 1 233 5.3E-69 T 13-10-2018 THITH_14655 6979d3d3dfffa5fd2a4841b697b83b33 233 SUPERFAMILY SSF52540 1 229 2.56E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14655 6979d3d3dfffa5fd2a4841b697b83b33 233 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_10055 b5c3cf02559a436d3bef721a422026df 496 SUPERFAMILY SSF51445 14 482 1.63E-156 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily THITH_10055 b5c3cf02559a436d3bef721a422026df 496 Pfam PF02446 4-alpha-glucanotransferase 21 467 2.2E-140 T 13-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 THITH_10055 b5c3cf02559a436d3bef721a422026df 496 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 119 486 6.6E-76 T 13-10-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 THITH_10055 b5c3cf02559a436d3bef721a422026df 496 Gene3D G3DSA:3.20.20.80 12 489 2.3E-176 T 13-10-2018 THITH_04360 3dcbf3a23946de95dc8120d8ec13cb5b 230 Hamap MF_00478 Ion-translocating oxidoreductase complex subunit E [rsxE]. 1 211 26.82 T 13-10-2018 IPR010968 Ion-translocating oxidoreductase complex subunit E GO:0016020|GO:0022900 THITH_04360 3dcbf3a23946de95dc8120d8ec13cb5b 230 TIGRFAM TIGR01948 rnfE: electron transport complex, RnfABCDGE type, E subunit 8 209 1.6E-78 T 13-10-2018 IPR010968 Ion-translocating oxidoreductase complex subunit E GO:0016020|GO:0022900 THITH_04360 3dcbf3a23946de95dc8120d8ec13cb5b 230 PIRSF PIRSF006102 1 218 7.9E-72 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 THITH_04360 3dcbf3a23946de95dc8120d8ec13cb5b 230 Pfam PF02508 Rnf-Nqr subunit, membrane protein 6 201 1.6E-59 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 60 1.0E-12 T 13-10-2018 IPR004176 Clp, N-terminal THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 SUPERFAMILY SSF52540 177 434 4.51E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 526 544 - T 13-10-2018 IPR028299 ClpA/B, conserved site 2 THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 SMART SM00382 495 662 9.7E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 SMART SM00382 214 359 4.4E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 321 1.0E-11 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 Pfam PF07724 AAA domain (Cdc48 subfamily) 494 655 4.0E-50 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 TIGRFAM TIGR02639 ClpA: ATP-dependent Clp protease ATP-binding subunit ClpA 3 741 0.0 T 13-10-2018 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA GO:0016887|GO:0043335 THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 Gene3D G3DSA:1.10.8.60 364 446 4.7E-33 T 13-10-2018 THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 617 1.4E-39 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 570 588 1.4E-39 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 499 517 1.4E-39 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 541 559 1.4E-39 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 SUPERFAMILY SSF52540 445 749 4.5E-77 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 SMART SM01086 661 751 3.7E-29 T 13-10-2018 IPR019489 Clp ATPase, C-terminal THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 Gene3D G3DSA:1.10.8.60 661 756 5.6E-26 T 13-10-2018 THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 310 322 - T 13-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 Gene3D G3DSA:3.40.50.300 174 363 3.0E-66 T 13-10-2018 THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 661 741 3.7E-22 T 13-10-2018 IPR019489 Clp ATPase, C-terminal THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 Gene3D G3DSA:3.40.50.300 447 659 9.2E-80 T 13-10-2018 THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 Gene3D G3DSA:1.10.1780.10 1 142 7.2E-38 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 THITH_08760 6cf0f099f0e14f682e8a5eefea985aaf 759 SUPERFAMILY SSF81923 1 141 7.19E-56 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 THITH_08960 40d9c25ac42a0d2c40b71932a6a456ff 488 SUPERFAMILY SSF51971 142 406 5.65E-67 T 13-10-2018 THITH_08960 40d9c25ac42a0d2c40b71932a6a456ff 488 PRINTS PR00419 Adrenodoxin reductase family signature 286 300 3.2E-24 T 13-10-2018 THITH_08960 40d9c25ac42a0d2c40b71932a6a456ff 488 PRINTS PR00419 Adrenodoxin reductase family signature 168 181 3.2E-24 T 13-10-2018 THITH_08960 40d9c25ac42a0d2c40b71932a6a456ff 488 PRINTS PR00419 Adrenodoxin reductase family signature 145 167 3.2E-24 T 13-10-2018 THITH_08960 40d9c25ac42a0d2c40b71932a6a456ff 488 PRINTS PR00419 Adrenodoxin reductase family signature 210 220 3.2E-24 T 13-10-2018 THITH_08960 40d9c25ac42a0d2c40b71932a6a456ff 488 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 145 469 3.2E-25 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THITH_08960 40d9c25ac42a0d2c40b71932a6a456ff 488 Gene3D G3DSA:3.50.50.60 250 405 3.5E-35 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_08960 40d9c25ac42a0d2c40b71932a6a456ff 488 SUPERFAMILY SSF51971 380 481 2.82E-10 T 13-10-2018 THITH_08960 40d9c25ac42a0d2c40b71932a6a456ff 488 Gene3D G3DSA:3.40.50.720 142 249 1.2E-19 T 13-10-2018 THITH_08960 40d9c25ac42a0d2c40b71932a6a456ff 488 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 487 8.4E-217 T 13-10-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 THITH_08960 40d9c25ac42a0d2c40b71932a6a456ff 488 Gene3D G3DSA:1.10.1060.10 11 141 3.9E-22 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_08960 40d9c25ac42a0d2c40b71932a6a456ff 488 SUPERFAMILY SSF46548 2 154 4.71E-39 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_08960 40d9c25ac42a0d2c40b71932a6a456ff 488 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 26 131 3.5E-23 T 13-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 THITH_13910 c7ad7cf7e852061f06fa22f25f7660b3 657 ProSitePatterns PS01156 TonB-dependent receptor proteins signature 2. 640 657 - T 13-10-2018 IPR010917 TonB-dependent receptor, conserved site THITH_13910 c7ad7cf7e852061f06fa22f25f7660b3 657 Pfam PF00593 TonB dependent receptor 193 655 3.3E-51 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel THITH_13910 c7ad7cf7e852061f06fa22f25f7660b3 657 SUPERFAMILY SSF56935 2 657 3.16E-108 T 13-10-2018 THITH_13910 c7ad7cf7e852061f06fa22f25f7660b3 657 Gene3D G3DSA:2.40.170.20 136 657 5.9E-99 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily THITH_13910 c7ad7cf7e852061f06fa22f25f7660b3 657 Gene3D G3DSA:2.170.130.10 9 134 7.6E-23 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily THITH_13910 c7ad7cf7e852061f06fa22f25f7660b3 657 Pfam PF07715 TonB-dependent Receptor Plug Domain 14 123 1.6E-17 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain THITH_11405 ac4e1d98c59a78c0d2e550583aadd19b 130 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 6 129 1.2E-48 T 13-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 THITH_11405 ac4e1d98c59a78c0d2e550583aadd19b 130 Pfam PF01597 Glycine cleavage H-protein 8 127 3.0E-47 T 13-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate THITH_11405 ac4e1d98c59a78c0d2e550583aadd19b 130 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 127 40.698 T 13-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 THITH_11405 ac4e1d98c59a78c0d2e550583aadd19b 130 SUPERFAMILY SSF51230 5 127 5.37E-45 T 13-10-2018 IPR011053 Single hybrid motif THITH_11405 ac4e1d98c59a78c0d2e550583aadd19b 130 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 49 78 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 THITH_11405 ac4e1d98c59a78c0d2e550583aadd19b 130 Gene3D G3DSA:2.40.50.100 2 129 4.1E-51 T 13-10-2018 THITH_02845 f7dc18696eabb879cdfa7f452d4cd2de 391 Gene3D G3DSA:3.30.870.10 12 193 4.1E-35 T 13-10-2018 THITH_02845 f7dc18696eabb879cdfa7f452d4cd2de 391 Pfam PF13091 PLD-like domain 31 137 4.3E-10 T 13-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THITH_02845 f7dc18696eabb879cdfa7f452d4cd2de 391 Pfam PF13091 PLD-like domain 215 341 8.1E-26 T 13-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THITH_02845 f7dc18696eabb879cdfa7f452d4cd2de 391 SUPERFAMILY SSF56024 169 359 2.47E-36 T 13-10-2018 THITH_02845 f7dc18696eabb879cdfa7f452d4cd2de 391 Gene3D G3DSA:3.30.870.10 202 343 3.6E-26 T 13-10-2018 THITH_02845 f7dc18696eabb879cdfa7f452d4cd2de 391 SMART SM00155 288 314 0.76 T 13-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 THITH_02845 f7dc18696eabb879cdfa7f452d4cd2de 391 SMART SM00155 112 139 2.3 T 13-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 THITH_02845 f7dc18696eabb879cdfa7f452d4cd2de 391 SUPERFAMILY SSF56024 4 198 1.01E-42 T 13-10-2018 THITH_17395 f2dad89b93b0e20a63e3e21039f90ada 727 Pfam PF13361 UvrD-like helicase C-terminal domain 277 617 2.1E-70 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 THITH_17395 f2dad89b93b0e20a63e3e21039f90ada 727 Gene3D G3DSA:1.10.10.160 114 187 4.5E-99 T 13-10-2018 IPR013986 DExx box DNA helicase domain superfamily THITH_17395 f2dad89b93b0e20a63e3e21039f90ada 727 Gene3D G3DSA:3.40.50.300 281 637 1.3E-123 T 13-10-2018 THITH_17395 f2dad89b93b0e20a63e3e21039f90ada 727 Gene3D G3DSA:3.40.50.300 10 273 4.5E-99 T 13-10-2018 THITH_17395 f2dad89b93b0e20a63e3e21039f90ada 727 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 272 6.1E-72 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 THITH_17395 f2dad89b93b0e20a63e3e21039f90ada 727 SUPERFAMILY SSF52540 6 643 2.2E-178 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_17395 f2dad89b93b0e20a63e3e21039f90ada 727 Gene3D G3DSA:1.10.486.10 382 539 1.3E-123 T 13-10-2018 THITH_15325 e787df05dd633f4f433967da05e1201e 449 SUPERFAMILY SSF56059 83 347 1.94E-68 T 13-10-2018 THITH_15325 e787df05dd633f4f433967da05e1201e 449 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.1E-44 T 13-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THITH_15325 e787df05dd633f4f433967da05e1201e 449 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 322 3.4E-81 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THITH_15325 e787df05dd633f4f433967da05e1201e 449 Gene3D G3DSA:3.30.470.20 87 433 4.5E-156 T 13-10-2018 THITH_15325 e787df05dd633f4f433967da05e1201e 449 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 154 168 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THITH_15325 e787df05dd633f4f433967da05e1201e 449 Gene3D G3DSA:3.40.50.20 1 85 1.2E-34 T 13-10-2018 THITH_15325 e787df05dd633f4f433967da05e1201e 449 Gene3D G3DSA:3.30.1490.20 131 203 4.5E-156 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 THITH_15325 e787df05dd633f4f433967da05e1201e 449 SMART SM00878 336 441 1.2E-66 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THITH_15325 e787df05dd633f4f433967da05e1201e 449 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 7.7E-229 T 13-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 THITH_15325 e787df05dd633f4f433967da05e1201e 449 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 3.5E-39 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THITH_15325 e787df05dd633f4f433967da05e1201e 449 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THITH_15325 e787df05dd633f4f433967da05e1201e 449 SUPERFAMILY SSF51246 331 444 2.56E-44 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 THITH_15325 e787df05dd633f4f433967da05e1201e 449 SUPERFAMILY SSF52440 1 113 7.19E-48 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily THITH_15400 26d858da492da64681d3914f0d976f88 163 Pfam PF02643 Uncharacterized ACR, COG1430 47 147 6.3E-33 T 13-10-2018 IPR003795 Protein of unknown function DUF192 THITH_15400 26d858da492da64681d3914f0d976f88 163 Gene3D G3DSA:2.60.120.1140 28 152 3.9E-39 T 13-10-2018 IPR038695 Saro_0823-like superfamily THITH_11255 25e9705ddb1ba866817c335b4a2dca5f 1317 Gene3D G3DSA:3.90.930.1 558 707 1.7E-5 T 13-10-2018 THITH_11255 25e9705ddb1ba866817c335b4a2dca5f 1317 Gene3D G3DSA:3.90.930.1 348 513 1.0E-5 T 13-10-2018 THITH_11255 25e9705ddb1ba866817c335b4a2dca5f 1317 Gene3D G3DSA:2.120.10.30 173 293 5.4E-20 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like THITH_11255 25e9705ddb1ba866817c335b4a2dca5f 1317 Gene3D G3DSA:2.120.10.30 41 172 2.2E-27 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like THITH_11255 25e9705ddb1ba866817c335b4a2dca5f 1317 SUPERFAMILY SSF101898 2 292 4.97E-24 T 13-10-2018 THITH_11255 25e9705ddb1ba866817c335b4a2dca5f 1317 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 640 677 6.5E-8 T 13-10-2018 IPR006530 YD repeat THITH_11255 25e9705ddb1ba866817c335b4a2dca5f 1317 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 403 439 8.6E-7 T 13-10-2018 IPR006530 YD repeat THITH_11255 25e9705ddb1ba866817c335b4a2dca5f 1317 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 340 378 0.0018 T 13-10-2018 IPR006530 YD repeat THITH_11255 25e9705ddb1ba866817c335b4a2dca5f 1317 SUPERFAMILY SSF101898 269 695 1.54E-5 T 13-10-2018 THITH_11255 25e9705ddb1ba866817c335b4a2dca5f 1317 Gene3D G3DSA:2.180.10.10 893 1177 3.4E-28 T 13-10-2018 THITH_11255 25e9705ddb1ba866817c335b4a2dca5f 1317 Pfam PF01436 NHL repeat 100 123 1.5E-4 T 13-10-2018 IPR001258 NHL repeat GO:0005515 THITH_11255 25e9705ddb1ba866817c335b4a2dca5f 1317 Pfam PF05593 RHS Repeat 407 438 2.0E-5 T 13-10-2018 IPR031325 RHS repeat THITH_11255 25e9705ddb1ba866817c335b4a2dca5f 1317 Pfam PF05593 RHS Repeat 661 697 1.7E-7 T 13-10-2018 IPR031325 RHS repeat THITH_11255 25e9705ddb1ba866817c335b4a2dca5f 1317 Pfam PF05593 RHS Repeat 640 677 6.0E-8 T 13-10-2018 IPR031325 RHS repeat THITH_11255 25e9705ddb1ba866817c335b4a2dca5f 1317 Pfam PF05593 RHS Repeat 919 948 2.5E-5 T 13-10-2018 IPR031325 RHS repeat THITH_11255 25e9705ddb1ba866817c335b4a2dca5f 1317 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1100 1177 1.7E-22 T 13-10-2018 IPR022385 Rhs repeat-associated core GO:0097264 THITH_12515 f10f1f0ea1308b2dab2709fabb12901b 387 Pfam PF04055 Radical SAM superfamily 130 278 2.9E-18 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THITH_12515 f10f1f0ea1308b2dab2709fabb12901b 387 SUPERFAMILY SSF102114 111 365 8.24E-33 T 13-10-2018 THITH_12515 f10f1f0ea1308b2dab2709fabb12901b 387 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 58 386 2.8E-98 T 13-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme THITH_12515 f10f1f0ea1308b2dab2709fabb12901b 387 SMART SM00729 124 329 0.002 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THITH_12515 f10f1f0ea1308b2dab2709fabb12901b 387 PIRSF PIRSF004869 50 363 2.2E-80 T 13-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted THITH_12515 f10f1f0ea1308b2dab2709fabb12901b 387 Gene3D G3DSA:3.20.20.70 118 336 5.9E-31 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_05025 08a27b56d25ca3d9d35c771dfa140707 282 Pfam PF00520 Ion transport protein 22 232 5.7E-42 T 13-10-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 THITH_05025 08a27b56d25ca3d9d35c771dfa140707 282 Gene3D G3DSA:1.10.287.70 130 225 2.3E-37 T 13-10-2018 THITH_05025 08a27b56d25ca3d9d35c771dfa140707 282 Gene3D G3DSA:1.20.120.350 8 118 9.4E-25 T 13-10-2018 IPR027359 Voltage-dependent channel domain superfamily THITH_05025 08a27b56d25ca3d9d35c771dfa140707 282 SUPERFAMILY SSF81324 19 230 1.15E-28 T 13-10-2018 THITH_05420 29c507e58ae4156739073a25543c88d5 772 SMART SM00086 87 129 1.4E-5 T 13-10-2018 IPR001610 PAC motif THITH_05420 29c507e58ae4156739073a25543c88d5 772 SUPERFAMILY SSF47226 518 672 5.63E-17 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 THITH_05420 29c507e58ae4156739073a25543c88d5 772 Pfam PF00072 Response regulator receiver domain 424 534 9.9E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_05420 29c507e58ae4156739073a25543c88d5 772 SUPERFAMILY SSF55874 221 391 1.18E-40 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_05420 29c507e58ae4156739073a25543c88d5 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 319 333 1.1E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_05420 29c507e58ae4156739073a25543c88d5 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 355 373 1.1E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_05420 29c507e58ae4156739073a25543c88d5 772 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 392 1.1E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_05420 29c507e58ae4156739073a25543c88d5 772 SUPERFAMILY SSF52172 421 545 5.98E-41 T 13-10-2018 IPR011006 CheY-like superfamily THITH_05420 29c507e58ae4156739073a25543c88d5 772 SUPERFAMILY SSF55785 21 127 5.06E-29 T 13-10-2018 IPR035965 PAS domain superfamily THITH_05420 29c507e58ae4156739073a25543c88d5 772 SUPERFAMILY SSF47384 152 233 1.35E-22 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_05420 29c507e58ae4156739073a25543c88d5 772 Gene3D G3DSA:3.30.565.10 231 396 7.0E-45 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_05420 29c507e58ae4156739073a25543c88d5 772 SMART SM00388 167 232 2.3E-22 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_05420 29c507e58ae4156739073a25543c88d5 772 Gene3D G3DSA:1.10.287.130 131 230 2.8E-31 T 13-10-2018 THITH_05420 29c507e58ae4156739073a25543c88d5 772 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 136 6.1E-25 T 13-10-2018 IPR000014 PAS domain THITH_05420 29c507e58ae4156739073a25543c88d5 772 Gene3D G3DSA:1.20.120.160 580 694 1.1E-14 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 THITH_05420 29c507e58ae4156739073a25543c88d5 772 Gene3D G3DSA:3.30.450.20 1 123 1.1E-35 T 13-10-2018 THITH_05420 29c507e58ae4156739073a25543c88d5 772 Pfam PF13426 PAS domain 25 128 1.4E-17 T 13-10-2018 IPR000014 PAS domain THITH_05420 29c507e58ae4156739073a25543c88d5 772 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 278 394 4.1E-28 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_05420 29c507e58ae4156739073a25543c88d5 772 Gene3D G3DSA:3.40.50.2300 419 549 1.2E-42 T 13-10-2018 THITH_05420 29c507e58ae4156739073a25543c88d5 772 SMART SM00091 15 81 4.2E-7 T 13-10-2018 IPR000014 PAS domain THITH_05420 29c507e58ae4156739073a25543c88d5 772 SMART SM00387 278 395 1.7E-32 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_05420 29c507e58ae4156739073a25543c88d5 772 Pfam PF00512 His Kinase A (phospho-acceptor) domain 167 232 4.4E-20 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_05420 29c507e58ae4156739073a25543c88d5 772 Pfam PF01627 Hpt domain 602 676 4.1E-10 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 THITH_05420 29c507e58ae4156739073a25543c88d5 772 SMART SM00448 422 535 1.1E-38 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_13895 c404d7c724be92bf8904d28f7aa85350 119 Gene3D G3DSA:1.20.120.330 4 119 9.0E-28 T 13-10-2018 THITH_13895 c404d7c724be92bf8904d28f7aa85350 119 Pfam PF05168 HEPN domain 6 118 1.5E-16 T 13-10-2018 IPR007842 HEPN domain THITH_15230 ee30c5047de25c7b0457d61660f3a1da 235 Gene3D G3DSA:3.40.50.300 4 234 5.7E-59 T 13-10-2018 THITH_15230 ee30c5047de25c7b0457d61660f3a1da 235 Pfam PF00005 ABC transporter 26 174 1.4E-26 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_15230 ee30c5047de25c7b0457d61660f3a1da 235 SUPERFAMILY SSF52540 21 227 8.87E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_15230 ee30c5047de25c7b0457d61660f3a1da 235 SMART SM00382 34 223 7.6E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_12960 a6019e5a6cc6b69c1e24e4c8ef128a27 793 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 149 159 - T 13-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12960 a6019e5a6cc6b69c1e24e4c8ef128a27 793 SUPERFAMILY SSF54292 6 78 1.56E-19 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 THITH_12960 a6019e5a6cc6b69c1e24e4c8ef128a27 793 SUPERFAMILY SSF53706 217 672 5.56E-87 T 13-10-2018 THITH_12960 a6019e5a6cc6b69c1e24e4c8ef128a27 793 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 102 114 - T 13-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12960 a6019e5a6cc6b69c1e24e4c8ef128a27 793 SMART SM00929 87 127 2.8E-20 T 13-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12960 a6019e5a6cc6b69c1e24e4c8ef128a27 793 Gene3D G3DSA:3.40.228.10 351 406 3.5E-15 T 13-10-2018 THITH_12960 a6019e5a6cc6b69c1e24e4c8ef128a27 793 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 87 121 9.6E-17 T 13-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12960 a6019e5a6cc6b69c1e24e4c8ef128a27 793 Gene3D G3DSA:3.40.50.740 503 683 6.2E-17 T 13-10-2018 THITH_12960 a6019e5a6cc6b69c1e24e4c8ef128a27 793 Gene3D G3DSA:3.10.20.740 5 156 2.1E-39 T 13-10-2018 THITH_12960 a6019e5a6cc6b69c1e24e4c8ef128a27 793 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 35 52 - T 13-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12960 a6019e5a6cc6b69c1e24e4c8ef128a27 793 SUPERFAMILY SSF54862 80 214 6.28E-36 T 13-10-2018 THITH_12960 a6019e5a6cc6b69c1e24e4c8ef128a27 793 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 9 645 2.1E-193 T 13-10-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12960 a6019e5a6cc6b69c1e24e4c8ef128a27 793 Gene3D G3DSA:3.40.50.740 284 350 3.5E-15 T 13-10-2018 THITH_12960 a6019e5a6cc6b69c1e24e4c8ef128a27 793 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 80 6.2E-19 T 13-10-2018 THITH_12960 a6019e5a6cc6b69c1e24e4c8ef128a27 793 Pfam PF00384 Molybdopterin oxidoreductase 562 646 2.6E-11 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12960 a6019e5a6cc6b69c1e24e4c8ef128a27 793 Pfam PF00384 Molybdopterin oxidoreductase 276 405 8.0E-16 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 Pfam PF00684 DnaJ central domain 149 209 2.9E-15 T 13-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 Gene3D G3DSA:1.10.287.110 1 113 5.9E-35 T 13-10-2018 IPR036869 Chaperone J-domain superfamily THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 SUPERFAMILY SSF49493 261 346 1.7E-22 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 SUPERFAMILY SSF57938 136 213 5.89E-23 T 13-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 Gene3D G3DSA:2.10.230.10 141 211 3.0E-25 T 13-10-2018 THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 Gene3D G3DSA:2.60.260.20 257 365 1.1E-29 T 13-10-2018 THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 SUPERFAMILY SSF49493 116 259 7.98E-22 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 351 8.5E-138 T 13-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 SUPERFAMILY SSF46565 2 113 5.5E-34 T 13-10-2018 IPR036869 Chaperone J-domain superfamily THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 SMART SM00271 4 62 9.5E-30 T 13-10-2018 IPR001623 DnaJ domain THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 381 42.195 T 13-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 Pfam PF00226 DnaJ domain 5 67 9.0E-26 T 13-10-2018 IPR001623 DnaJ domain THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 PRINTS PR00625 DnaJ domain signature 25 40 1.4E-28 T 13-10-2018 IPR001623 DnaJ domain THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 PRINTS PR00625 DnaJ domain signature 42 62 1.4E-28 T 13-10-2018 IPR001623 DnaJ domain THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 PRINTS PR00625 DnaJ domain signature 7 25 1.4E-28 T 13-10-2018 IPR001623 DnaJ domain THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 PRINTS PR00625 DnaJ domain signature 62 81 1.4E-28 T 13-10-2018 IPR001623 DnaJ domain THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 Pfam PF01556 DnaJ C terminal domain 122 335 4.5E-46 T 13-10-2018 IPR002939 Chaperone DnaJ, C-terminal THITH_13120 de482cb70e60c5f4cdc5560ab2497928 383 ProSitePatterns PS00636 Nt-dnaJ domain signature. 47 66 - T 13-10-2018 IPR018253 DnaJ domain, conserved site THITH_07975 d1323fde09e0248d6228ec326278452d 99 Hamap MF_00381 Integration host factor subunit beta [ihfB]. 1 94 30.669 T 13-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 THITH_07975 d1323fde09e0248d6228ec326278452d 99 SUPERFAMILY SSF47729 1 91 1.47E-31 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 THITH_07975 d1323fde09e0248d6228ec326278452d 99 TIGRFAM TIGR00988 hip: integration host factor, beta subunit 1 92 1.5E-46 T 13-10-2018 IPR005685 Integration host factor, beta subunit GO:0003677|GO:0005694|GO:0006310|GO:0006355 THITH_07975 d1323fde09e0248d6228ec326278452d 99 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 47 66 - T 13-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 THITH_07975 d1323fde09e0248d6228ec326278452d 99 SMART SM00411 1 91 1.1E-43 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THITH_07975 d1323fde09e0248d6228ec326278452d 99 Pfam PF00216 Bacterial DNA-binding protein 1 91 1.1E-30 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THITH_07975 d1323fde09e0248d6228ec326278452d 99 PRINTS PR01727 Prokaryotic integration host factor signature 59 72 1.1E-17 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THITH_07975 d1323fde09e0248d6228ec326278452d 99 PRINTS PR01727 Prokaryotic integration host factor signature 41 56 1.1E-17 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THITH_07975 d1323fde09e0248d6228ec326278452d 99 PRINTS PR01727 Prokaryotic integration host factor signature 75 89 1.1E-17 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THITH_07975 d1323fde09e0248d6228ec326278452d 99 Gene3D G3DSA:4.10.520.10 1 93 5.3E-34 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 THITH_15190 916980828a94576aa595fe027bfa70c2 978 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 36 966 19.329 T 13-10-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 THITH_15190 916980828a94576aa595fe027bfa70c2 978 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 43 282 6.6E-81 T 13-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 THITH_15190 916980828a94576aa595fe027bfa70c2 978 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 569 824 5.8E-81 T 13-10-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 THITH_15190 916980828a94576aa595fe027bfa70c2 978 SUPERFAMILY SSF81593 834 965 3.37E-31 T 13-10-2018 THITH_15190 916980828a94576aa595fe027bfa70c2 978 Gene3D G3DSA:3.30.460.100 48 289 3.8E-80 T 13-10-2018 THITH_15190 916980828a94576aa595fe027bfa70c2 978 Gene3D G3DSA:3.30.460.100 578 830 1.5E-86 T 13-10-2018 THITH_15190 916980828a94576aa595fe027bfa70c2 978 SUPERFAMILY SSF81301 22 295 7.28E-81 T 13-10-2018 THITH_15190 916980828a94576aa595fe027bfa70c2 978 SUPERFAMILY SSF81301 541 834 3.07E-81 T 13-10-2018 THITH_15190 916980828a94576aa595fe027bfa70c2 978 Pfam PF08335 GlnD PII-uridylyltransferase 845 934 9.5E-9 T 13-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 THITH_15190 916980828a94576aa595fe027bfa70c2 978 Pfam PF08335 GlnD PII-uridylyltransferase 306 445 1.1E-41 T 13-10-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 THITH_15190 916980828a94576aa595fe027bfa70c2 978 Gene3D G3DSA:1.20.120.1510 466 577 2.5E-30 T 13-10-2018 THITH_15190 916980828a94576aa595fe027bfa70c2 978 SUPERFAMILY SSF81593 296 445 1.96E-39 T 13-10-2018 THITH_15190 916980828a94576aa595fe027bfa70c2 978 Gene3D G3DSA:1.20.120.330 831 966 7.3E-39 T 13-10-2018 THITH_15190 916980828a94576aa595fe027bfa70c2 978 Gene3D G3DSA:1.20.120.330 294 448 2.3E-48 T 13-10-2018 THITH_06570 b80cbba3bdbf85586965337b68eccf76 348 Gene3D G3DSA:3.40.30.10 224 347 9.2E-15 T 13-10-2018 THITH_06570 b80cbba3bdbf85586965337b68eccf76 348 Gene3D G3DSA:3.40.30.10 56 196 1.8E-24 T 13-10-2018 THITH_06570 b80cbba3bdbf85586965337b68eccf76 348 Pfam PF13098 Thioredoxin-like domain 77 174 1.3E-17 T 13-10-2018 IPR012336 Thioredoxin-like fold THITH_06570 b80cbba3bdbf85586965337b68eccf76 348 Pfam PF13098 Thioredoxin-like domain 226 319 7.3E-9 T 13-10-2018 IPR012336 Thioredoxin-like fold THITH_06570 b80cbba3bdbf85586965337b68eccf76 348 SUPERFAMILY SSF52833 57 184 2.18E-15 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_06570 b80cbba3bdbf85586965337b68eccf76 348 SUPERFAMILY SSF52833 226 340 6.11E-9 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_02560 7b30fdbdaa6fbac92ff2f479ff6ab541 399 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 5 398 8.0E-115 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 THITH_02560 7b30fdbdaa6fbac92ff2f479ff6ab541 399 Pfam PF01479 S4 domain 338 381 4.4E-8 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_02560 7b30fdbdaa6fbac92ff2f479ff6ab541 399 SUPERFAMILY SSF52374 4 316 1.2E-92 T 13-10-2018 THITH_02560 7b30fdbdaa6fbac92ff2f479ff6ab541 399 SMART SM00363 337 399 1.2E-5 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_02560 7b30fdbdaa6fbac92ff2f479ff6ab541 399 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 41 51 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_02560 7b30fdbdaa6fbac92ff2f479ff6ab541 399 Gene3D G3DSA:3.10.290.10 328 398 7.5E-18 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 THITH_02560 7b30fdbdaa6fbac92ff2f479ff6ab541 399 Gene3D G3DSA:1.10.240.10 218 327 8.5E-30 T 13-10-2018 THITH_02560 7b30fdbdaa6fbac92ff2f479ff6ab541 399 SUPERFAMILY SSF55174 321 398 1.83E-17 T 13-10-2018 THITH_02560 7b30fdbdaa6fbac92ff2f479ff6ab541 399 Gene3D G3DSA:3.40.50.620 1 217 6.0E-72 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_02560 7b30fdbdaa6fbac92ff2f479ff6ab541 399 Pfam PF00579 tRNA synthetases class I (W and Y) 30 317 1.4E-72 T 13-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_02560 7b30fdbdaa6fbac92ff2f479ff6ab541 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 210 222 1.1E-25 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 THITH_02560 7b30fdbdaa6fbac92ff2f479ff6ab541 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 45 67 1.1E-25 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 THITH_02560 7b30fdbdaa6fbac92ff2f479ff6ab541 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 160 175 1.1E-25 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 THITH_02560 7b30fdbdaa6fbac92ff2f479ff6ab541 399 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 177 199 1.1E-25 T 13-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 THITH_02560 7b30fdbdaa6fbac92ff2f479ff6ab541 399 Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. 1 398 48.442 T 13-10-2018 IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 GO:0004831 KEGG: 00970+6.1.1.1 THITH_14675 8c6ddc424ffeefa609ac11757b3e484b 318 Gene3D G3DSA:3.40.1390.20 9 134 1.8E-14 T 13-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily THITH_14675 8c6ddc424ffeefa609ac11757b3e484b 318 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 10 308 1.1E-84 T 13-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 THITH_14675 8c6ddc424ffeefa609ac11757b3e484b 318 SUPERFAMILY SSF53795 140 297 1.62E-29 T 13-10-2018 THITH_14675 8c6ddc424ffeefa609ac11757b3e484b 318 Gene3D G3DSA:3.40.50.300 135 317 2.7E-56 T 13-10-2018 THITH_14675 8c6ddc424ffeefa609ac11757b3e484b 318 Pfam PF02603 HPr Serine kinase N terminus 9 131 2.7E-16 T 13-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 THITH_14675 8c6ddc424ffeefa609ac11757b3e484b 318 Pfam PF07475 HPr Serine kinase C-terminal domain 134 304 7.7E-55 T 13-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 THITH_14675 8c6ddc424ffeefa609ac11757b3e484b 318 SUPERFAMILY SSF75138 4 135 5.36E-16 T 13-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily THITH_17010 68e07e65a9e659a3da46451396cbc164 286 Gene3D G3DSA:1.10.287.80 6 282 2.4E-107 T 13-10-2018 THITH_17010 68e07e65a9e659a3da46451396cbc164 286 Gene3D G3DSA:3.40.1380.10 61 205 2.4E-107 T 13-10-2018 THITH_17010 68e07e65a9e659a3da46451396cbc164 286 Hamap MF_00815 ATP synthase gamma chain [atpG]. 1 286 36.416 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17010 68e07e65a9e659a3da46451396cbc164 286 Pfam PF00231 ATP synthase 4 285 3.3E-95 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17010 68e07e65a9e659a3da46451396cbc164 286 SUPERFAMILY SSF52943 2 286 1.06E-94 T 13-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17010 68e07e65a9e659a3da46451396cbc164 286 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 1 286 1.8E-108 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17010 68e07e65a9e659a3da46451396cbc164 286 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 272 285 - T 13-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17010 68e07e65a9e659a3da46451396cbc164 286 PRINTS PR00126 ATP synthase gamma subunit signature 264 285 8.4E-36 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17010 68e07e65a9e659a3da46451396cbc164 286 PRINTS PR00126 ATP synthase gamma subunit signature 166 183 8.4E-36 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17010 68e07e65a9e659a3da46451396cbc164 286 PRINTS PR00126 ATP synthase gamma subunit signature 73 92 8.4E-36 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17010 68e07e65a9e659a3da46451396cbc164 286 PRINTS PR00126 ATP synthase gamma subunit signature 233 252 8.4E-36 T 13-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_07400 93530400cddd508fe5783730223f7a76 184 Pfam PF01871 AMMECR1 24 172 5.3E-40 T 13-10-2018 IPR002733 AMMECR1 domain THITH_07400 93530400cddd508fe5783730223f7a76 184 Gene3D G3DSA:3.30.1490.150 102 172 2.2E-41 T 13-10-2018 THITH_07400 93530400cddd508fe5783730223f7a76 184 SUPERFAMILY SSF143447 25 177 8.24E-47 T 13-10-2018 IPR036071 AMMECR1 domain superfamily THITH_07400 93530400cddd508fe5783730223f7a76 184 Gene3D G3DSA:3.30.700.20 21 101 2.2E-41 T 13-10-2018 IPR027485 AMMECR1, N-terminal THITH_07400 93530400cddd508fe5783730223f7a76 184 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 1 173 1.7E-55 T 13-10-2018 IPR027623 AmmeMemoRadiSam system protein A THITH_15960 35e57c8b780929db33c7377ae6712735 472 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 8 464 49.43 T 13-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 THITH_15960 35e57c8b780929db33c7377ae6712735 472 SMART SM00996 12 471 0.0 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THITH_15960 35e57c8b780929db33c7377ae6712735 472 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 13 464 7.1E-189 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THITH_15960 35e57c8b780929db33c7377ae6712735 472 PIRSF PIRSF001109 1 472 1.8E-197 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THITH_15960 35e57c8b780929db33c7377ae6712735 472 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 233 392 7.9E-85 T 13-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THITH_15960 35e57c8b780929db33c7377ae6712735 472 SUPERFAMILY SSF51735 233 392 8.69E-81 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_15960 35e57c8b780929db33c7377ae6712735 472 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 12 471 3.7E-148 T 13-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THITH_15960 35e57c8b780929db33c7377ae6712735 472 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 255 271 - T 13-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THITH_15960 35e57c8b780929db33c7377ae6712735 472 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 84 98 - T 13-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THITH_15960 35e57c8b780929db33c7377ae6712735 472 SMART SM00997 233 392 2.4E-117 T 13-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 THITH_15960 35e57c8b780929db33c7377ae6712735 472 SUPERFAMILY SSF52283 11 472 3.85E-117 T 13-10-2018 THITH_15960 35e57c8b780929db33c7377ae6712735 472 Gene3D G3DSA:3.40.50.1480 13 472 6.8E-244 T 13-10-2018 THITH_15960 35e57c8b780929db33c7377ae6712735 472 Gene3D G3DSA:3.40.50.720 235 392 6.8E-244 T 13-10-2018 THITH_12220 ffb85cb79a3f1abb64e10677c956e0a0 198 Gene3D G3DSA:1.10.8.420 1 52 9.6E-16 T 13-10-2018 THITH_12220 ffb85cb79a3f1abb64e10677c956e0a0 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 95.976 T 13-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 THITH_12220 ffb85cb79a3f1abb64e10677c956e0a0 198 Gene3D G3DSA:3.40.1360.10 77 198 4.9E-39 T 13-10-2018 THITH_12220 ffb85cb79a3f1abb64e10677c956e0a0 198 Pfam PF13662 Toprim domain 81 171 8.6E-22 T 13-10-2018 IPR006171 TOPRIM domain THITH_12220 ffb85cb79a3f1abb64e10677c956e0a0 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 196 4.9E-69 T 13-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 THITH_12220 ffb85cb79a3f1abb64e10677c956e0a0 198 Pfam PF02132 RecR protein 40 78 1.5E-11 T 13-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger THITH_12220 ffb85cb79a3f1abb64e10677c956e0a0 198 SMART SM00493 80 165 2.1E-8 T 13-10-2018 IPR006171 TOPRIM domain THITH_12220 ffb85cb79a3f1abb64e10677c956e0a0 198 SUPERFAMILY SSF111304 3 198 1.07E-67 T 13-10-2018 IPR023627 Recombination protein RecR THITH_12730 c94f99859044a51d650e0902a00e8720 130 SUPERFAMILY SSF46626 42 129 2.98E-7 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_12730 c94f99859044a51d650e0902a00e8720 130 Pfam PF07635 Planctomycete cytochrome C 52 108 3.0E-10 T 13-10-2018 IPR011429 Cytochrome C, Planctomycete-type THITH_07505 879596cc0d111768738f580e9bde14bb 313 Gene3D G3DSA:3.30.70.20 220 305 2.3E-9 T 13-10-2018 THITH_07505 879596cc0d111768738f580e9bde14bb 313 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 272 283 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_07505 879596cc0d111768738f580e9bde14bb 313 TIGRFAM TIGR02163 napH_: ferredoxin-type protein, NapH/MauN family 34 290 3.1E-99 T 13-10-2018 IPR011886 Ferredoxin-type protein, NapH/MauN family THITH_07505 879596cc0d111768738f580e9bde14bb 313 Pfam PF12801 4Fe-4S binding domain 191 228 1.9E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_07505 879596cc0d111768738f580e9bde14bb 313 Pfam PF12801 4Fe-4S binding domain 100 140 4.3E-13 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_07505 879596cc0d111768738f580e9bde14bb 313 Pfam PF13237 4Fe-4S dicluster domain 233 283 2.1E-9 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_07505 879596cc0d111768738f580e9bde14bb 313 SUPERFAMILY SSF54862 109 289 5.02E-23 T 13-10-2018 THITH_00630 647ff14e067dcecf21a2591269cba911 613 Gene3D G3DSA:3.90.228.20 237 588 2.4E-265 T 13-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 THITH_00630 647ff14e067dcecf21a2591269cba911 613 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 261 269 - T 13-10-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 THITH_00630 647ff14e067dcecf21a2591269cba911 613 Gene3D G3DSA:2.170.8.10 49 395 2.4E-265 T 13-10-2018 THITH_00630 647ff14e067dcecf21a2591269cba911 613 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 14 233 2.8E-106 T 13-10-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 THITH_00630 647ff14e067dcecf21a2591269cba911 613 PIRSF PIRSF001348 1 598 1.2E-277 T 13-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 THITH_00630 647ff14e067dcecf21a2591269cba911 613 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 2 600 51.04 T 13-10-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 THITH_00630 647ff14e067dcecf21a2591269cba911 613 SUPERFAMILY SSF68923 5 236 1.83E-106 T 13-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 THITH_00630 647ff14e067dcecf21a2591269cba911 613 Gene3D G3DSA:3.40.449.10 14 236 2.4E-265 T 13-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 THITH_00630 647ff14e067dcecf21a2591269cba911 613 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 237 593 3.3E-167 T 13-10-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 THITH_00630 647ff14e067dcecf21a2591269cba911 613 SUPERFAMILY SSF53795 237 599 1.85E-158 T 13-10-2018 THITH_11670 1c25ad9f0ebd72f315e76dc09dcb5e39 805 Pfam PF00384 Molybdopterin oxidoreductase 2 378 8.2E-24 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_11670 1c25ad9f0ebd72f315e76dc09dcb5e39 805 SUPERFAMILY SSF53706 1 637 1.23E-224 T 13-10-2018 THITH_11670 1c25ad9f0ebd72f315e76dc09dcb5e39 805 SUPERFAMILY SSF50692 617 805 2.49E-43 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily THITH_11670 1c25ad9f0ebd72f315e76dc09dcb5e39 805 Gene3D G3DSA:3.40.50.740 312 472 2.7E-53 T 13-10-2018 THITH_11670 1c25ad9f0ebd72f315e76dc09dcb5e39 805 TIGRFAM TIGR01553 formate-DH-alph: formate dehydrogenase-N alpha subunit 1 804 0.0 T 13-10-2018 IPR006443 Formate dehydrogenase-N, alpha subunit GO:0008863|GO:0009055|GO:0043546|GO:0045333|GO:0047111 THITH_11670 1c25ad9f0ebd72f315e76dc09dcb5e39 805 Pfam PF01568 Molydopterin dinucleotide binding domain 682 798 3.1E-15 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 THITH_11670 1c25ad9f0ebd72f315e76dc09dcb5e39 805 Gene3D G3DSA:2.40.40.20 628 805 3.2E-68 T 13-10-2018 THITH_11670 1c25ad9f0ebd72f315e76dc09dcb5e39 805 Gene3D G3DSA:3.40.228.10 1 271 7.7E-78 T 13-10-2018 THITH_11670 1c25ad9f0ebd72f315e76dc09dcb5e39 805 Gene3D G3DSA:3.40.228.10 520 627 1.1E-24 T 13-10-2018 THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 Pfam PF00873 AcrB/AcrD/AcrF family 8 1021 2.6E-148 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 Gene3D G3DSA:3.30.70.1320 136 325 2.2E-240 T 13-10-2018 THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 SUPERFAMILY SSF82693 45 133 1.88E-22 T 13-10-2018 THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 Gene3D G3DSA:3.30.2090.10 715 802 2.2E-240 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 SUPERFAMILY SSF82866 802 1026 2.62E-43 T 13-10-2018 THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 Gene3D G3DSA:1.20.1640.10 14 501 2.2E-240 T 13-10-2018 THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 1.4E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 PRINTS PR00702 Acriflavin resistance protein family signature 14 38 1.4E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 PRINTS PR00702 Acriflavin resistance protein family signature 329 352 1.4E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 1.4E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 PRINTS PR00702 Acriflavin resistance protein family signature 42 60 1.4E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 1.4E-22 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 SUPERFAMILY SSF82714 182 263 1.2E-5 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 Gene3D G3DSA:3.30.2090.10 177 268 2.2E-240 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 Gene3D G3DSA:3.30.70.1430 559 665 2.2E-240 T 13-10-2018 THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 SUPERFAMILY SSF82866 291 484 1.06E-34 T 13-10-2018 THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 Gene3D G3DSA:1.20.1640.10 502 1018 2.2E-240 T 13-10-2018 THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 SUPERFAMILY SSF82714 728 799 2.09E-9 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 Gene3D G3DSA:3.30.70.1440 666 862 2.2E-240 T 13-10-2018 THITH_09150 5fd3600c26b25e3e617855043b91a97f 1036 Gene3D G3DSA:3.30.70.1430 44 810 2.2E-240 T 13-10-2018 THITH_13425 58429b362e32f0d84cc036ec6ada356d 425 Pfam PF06689 ClpX C4-type zinc finger 14 51 2.1E-20 T 13-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 THITH_13425 58429b362e32f0d84cc036ec6ada356d 425 SUPERFAMILY SSF57716 14 49 7.41E-12 T 13-10-2018 THITH_13425 58429b362e32f0d84cc036ec6ada356d 425 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 10 411 1.7E-206 T 13-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 THITH_13425 58429b362e32f0d84cc036ec6ada356d 425 Gene3D G3DSA:1.10.8.60 315 423 2.6E-42 T 13-10-2018 THITH_13425 58429b362e32f0d84cc036ec6ada356d 425 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 316 393 3.4E-17 T 13-10-2018 IPR019489 Clp ATPase, C-terminal THITH_13425 58429b362e32f0d84cc036ec6ada356d 425 SMART SM01086 316 410 3.4E-35 T 13-10-2018 IPR019489 Clp ATPase, C-terminal THITH_13425 58429b362e32f0d84cc036ec6ada356d 425 Gene3D G3DSA:3.30.50.30 3 53 1.0E-25 T 13-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily THITH_13425 58429b362e32f0d84cc036ec6ada356d 425 Pfam PF07724 AAA domain (Cdc48 subfamily) 112 309 9.3E-50 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THITH_13425 58429b362e32f0d84cc036ec6ada356d 425 SUPERFAMILY SSF52540 62 400 2.21E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13425 58429b362e32f0d84cc036ec6ada356d 425 SMART SM00382 111 417 2.0E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_13425 58429b362e32f0d84cc036ec6ada356d 425 SMART SM00994 13 52 1.8E-24 T 13-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 THITH_13425 58429b362e32f0d84cc036ec6ada356d 425 Gene3D G3DSA:3.40.50.300 57 314 2.0E-108 T 13-10-2018 THITH_13425 58429b362e32f0d84cc036ec6ada356d 425 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 7 414 53.481 T 13-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 THITH_04355 6fda772f810695739cd1290a33ac09f1 216 SMART SM00525 186 206 9.4E-4 T 13-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 THITH_04355 6fda772f810695739cd1290a33ac09f1 216 Gene3D G3DSA:1.10.340.30 21 132 4.4E-77 T 13-10-2018 THITH_04355 6fda772f810695739cd1290a33ac09f1 216 TIGRFAM TIGR01083 nth: endonuclease III 5 194 1.3E-83 T 13-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 THITH_04355 6fda772f810695739cd1290a33ac09f1 216 PIRSF PIRSF001435 1 212 8.2E-50 T 13-10-2018 THITH_04355 6fda772f810695739cd1290a33ac09f1 216 ProSitePatterns PS01155 Endonuclease III family signature. 102 131 - T 13-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 THITH_04355 6fda772f810695739cd1290a33ac09f1 216 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 187 203 - T 13-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 THITH_04355 6fda772f810695739cd1290a33ac09f1 216 Hamap MF_00942 Endonuclease III [nth]. 3 209 38.138 T 13-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 THITH_04355 6fda772f810695739cd1290a33ac09f1 216 SUPERFAMILY SSF48150 3 208 3.77E-74 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 THITH_04355 6fda772f810695739cd1290a33ac09f1 216 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 187 203 2.9E-4 T 13-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 THITH_04355 6fda772f810695739cd1290a33ac09f1 216 Pfam PF00633 Helix-hairpin-helix motif 100 127 4.9E-8 T 13-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 THITH_04355 6fda772f810695739cd1290a33ac09f1 216 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 165 1.5E-20 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THITH_04355 6fda772f810695739cd1290a33ac09f1 216 SMART SM00478 38 185 1.8E-59 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THITH_04355 6fda772f810695739cd1290a33ac09f1 216 Gene3D G3DSA:1.10.1670.10 11 203 4.4E-77 T 13-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 THITH_13990 a3d0f0316c784e88c05957304ac67d42 112 SUPERFAMILY SSF54913 1 112 6.67E-47 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THITH_13990 a3d0f0316c784e88c05957304ac67d42 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 3.0E-44 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THITH_13990 a3d0f0316c784e88c05957304ac67d42 112 Gene3D G3DSA:3.30.70.120 1 112 1.3E-49 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THITH_13990 a3d0f0316c784e88c05957304ac67d42 112 PIRSF PIRSF039144 1 112 8.3E-57 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THITH_13990 a3d0f0316c784e88c05957304ac67d42 112 PRINTS PR00340 P-II protein signature 2 17 1.2E-44 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THITH_13990 a3d0f0316c784e88c05957304ac67d42 112 PRINTS PR00340 P-II protein signature 83 103 1.2E-44 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THITH_13990 a3d0f0316c784e88c05957304ac67d42 112 PRINTS PR00340 P-II protein signature 52 75 1.2E-44 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THITH_13990 a3d0f0316c784e88c05957304ac67d42 112 PRINTS PR00340 P-II protein signature 23 41 1.2E-44 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THITH_13990 a3d0f0316c784e88c05957304ac67d42 112 SMART SM00938 4 105 7.8E-69 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THITH_13990 a3d0f0316c784e88c05957304ac67d42 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 13-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 THITH_13990 a3d0f0316c784e88c05957304ac67d42 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 13-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 SUPERFAMILY SSF47323 393 548 1.33E-38 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 Gene3D G3DSA:2.20.28.20 146 180 7.7E-153 T 13-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 Gene3D G3DSA:2.40.50.140 572 683 7.3E-33 T 13-10-2018 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 Gene3D G3DSA:3.40.50.620 12 382 7.7E-153 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 562 683 1.4E-43 T 13-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 SUPERFAMILY SSF52374 9 389 3.05E-101 T 13-10-2018 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 46 60 6.8E-25 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 387 398 6.8E-25 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 255 266 6.8E-25 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 94 105 6.8E-25 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 14 27 6.8E-25 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 PRINTS PR01041 Methionyl-tRNA synthetase signature 294 309 6.8E-25 T 13-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 19 30 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 SUPERFAMILY SSF57770 146 180 6.28E-12 T 13-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 Hamap MF_00098 Methionine--tRNA ligase [metG]. 10 549 40.0 T 13-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 Gene3D G3DSA:1.10.730.10 383 540 2.6E-31 T 13-10-2018 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 SUPERFAMILY SSF50249 577 682 1.13E-30 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 12 539 2.9E-176 T 13-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 Pfam PF09334 tRNA synthetases class I (M) 12 399 2.7E-154 T 13-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_04400 ab69ba094a183d7ee598c8daf492395d 683 Pfam PF01588 Putative tRNA binding domain 588 680 1.3E-22 T 13-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 THITH_04220 6f6d749bc22478bd4a6006968e8775f9 244 Pfam PF00685 Sulfotransferase domain 42 172 7.9E-10 T 13-10-2018 IPR000863 Sulfotransferase domain GO:0008146 THITH_04220 6f6d749bc22478bd4a6006968e8775f9 244 SUPERFAMILY SSF52540 40 243 1.78E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_04220 6f6d749bc22478bd4a6006968e8775f9 244 Gene3D G3DSA:3.40.50.300 39 215 1.2E-39 T 13-10-2018 THITH_00035 8a40a5e59e892da29697d4528633f898 681 Pfam PF01432 Peptidase family M3 224 677 4.8E-145 T 13-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 THITH_00035 8a40a5e59e892da29697d4528633f898 681 SUPERFAMILY SSF55486 2 677 4.48E-191 T 13-10-2018 THITH_00035 8a40a5e59e892da29697d4528633f898 681 Gene3D G3DSA:1.10.1370.40 14 675 4.7E-257 T 13-10-2018 THITH_00035 8a40a5e59e892da29697d4528633f898 681 Gene3D G3DSA:1.10.1370.10 141 610 4.7E-257 T 13-10-2018 IPR024077 Neurolysin/Thimet oligopeptidase, domain 2 THITH_03440 f5037d41478b87f2020b6126b9bda281 75 Gene3D G3DSA:1.10.10.10 6 72 9.1E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_03440 f5037d41478b87f2020b6126b9bda281 75 Pfam PF04255 Protein of unknown function (DUF433) 7 62 1.1E-26 T 13-10-2018 IPR007367 Protein of unknown function DUF433 THITH_03440 f5037d41478b87f2020b6126b9bda281 75 SUPERFAMILY SSF46689 1 69 9.32E-24 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_09090 dda152981483448343bb535b6abbbed1 246 Gene3D G3DSA:3.40.50.150 17 240 7.7E-70 T 13-10-2018 THITH_09090 dda152981483448343bb535b6abbbed1 246 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 17 240 35.59 T 13-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 THITH_09090 dda152981483448343bb535b6abbbed1 246 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 17 234 2.6E-76 T 13-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 THITH_09090 dda152981483448343bb535b6abbbed1 246 Pfam PF13489 Methyltransferase domain 57 210 4.4E-24 T 13-10-2018 THITH_09090 dda152981483448343bb535b6abbbed1 246 SUPERFAMILY SSF53335 19 240 3.65E-45 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_16955 ec13949f56ec371377afac62e5109d30 286 Gene3D G3DSA:3.40.50.620 1 268 5.9E-48 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_16955 ec13949f56ec371377afac62e5109d30 286 PIRSF PIRSF004976 1 273 4.6E-58 T 13-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 THITH_16955 ec13949f56ec371377afac62e5109d30 286 Pfam PF01171 PP-loop family 48 216 3.7E-15 T 13-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 THITH_16955 ec13949f56ec371377afac62e5109d30 286 SUPERFAMILY SSF52402 26 240 7.72E-49 T 13-10-2018 THITH_13275 dda2aa5e7ebcf212dc9e4931efa6cd4b 689 Pfam PF00593 TonB dependent receptor 202 687 8.0E-47 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel THITH_13275 dda2aa5e7ebcf212dc9e4931efa6cd4b 689 Pfam PF07715 TonB-dependent Receptor Plug Domain 45 152 1.2E-16 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain THITH_13275 dda2aa5e7ebcf212dc9e4931efa6cd4b 689 SUPERFAMILY SSF56935 28 688 3.22E-111 T 13-10-2018 THITH_13275 dda2aa5e7ebcf212dc9e4931efa6cd4b 689 Gene3D G3DSA:2.40.170.20 168 688 1.9E-80 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily THITH_13275 dda2aa5e7ebcf212dc9e4931efa6cd4b 689 Gene3D G3DSA:2.170.130.10 31 157 1.6E-25 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 SUPERFAMILY SSF88946 61 170 8.24E-44 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 TIGRFAM TIGR02394 rpoS_proteo: RNA polymerase sigma factor RpoS 61 336 6.0E-127 T 13-10-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 Pfam PF04539 Sigma-70 region 3 187 256 7.2E-16 T 13-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 SUPERFAMILY SSF88659 235 329 3.36E-25 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 296 322 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 Hamap MF_00959 RNA polymerase sigma factor RpoS [rpoS]. 10 337 38.419 T 13-10-2018 IPR012761 RNA polymerase sigma factor RpoS GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 Gene3D G3DSA:1.10.601.10 38 172 1.3E-45 T 13-10-2018 THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 SUPERFAMILY SSF88659 176 250 9.16E-14 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 100 325 4.3E-39 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 Pfam PF00140 Sigma-70 factor, region 1.2 65 96 6.7E-11 T 13-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 127 140 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 Gene3D G3DSA:1.10.10.10 254 334 1.1E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 Pfam PF04545 Sigma-70, region 4 271 324 1.3E-15 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 Pfam PF04542 Sigma-70 region 2 103 172 4.8E-21 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 Gene3D G3DSA:1.10.10.10 176 251 1.2E-17 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 PRINTS PR00046 Major sigma-70 factor signature 151 159 4.7E-26 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 PRINTS PR00046 Major sigma-70 factor signature 275 287 4.7E-26 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 PRINTS PR00046 Major sigma-70 factor signature 311 322 4.7E-26 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 PRINTS PR00046 Major sigma-70 factor signature 127 140 4.7E-26 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_04825 84b9419f1d2a2cc46e9b1c8d1ee19bc0 340 PRINTS PR00046 Major sigma-70 factor signature 296 311 4.7E-26 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_12310 337dd941e0de29ef90ec8a955afdd1f4 106 Gene3D G3DSA:3.30.70.120 5 104 3.8E-23 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THITH_12310 337dd941e0de29ef90ec8a955afdd1f4 106 SUPERFAMILY SSF54913 5 100 1.17E-15 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THITH_06565 3d2020cd4d8a3032f7cba9248c81a31a 428 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 2.2E-30 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THITH_06565 3d2020cd4d8a3032f7cba9248c81a31a 428 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 2.2E-30 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THITH_06565 3d2020cd4d8a3032f7cba9248c81a31a 428 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 2.2E-30 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THITH_06565 3d2020cd4d8a3032f7cba9248c81a31a 428 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 2.2E-30 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THITH_06565 3d2020cd4d8a3032f7cba9248c81a31a 428 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 2.2E-30 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THITH_06565 3d2020cd4d8a3032f7cba9248c81a31a 428 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 107 6.3E-30 T 13-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 THITH_06565 3d2020cd4d8a3032f7cba9248c81a31a 428 Gene3D G3DSA:3.30.930.10 105 426 1.2E-112 T 13-10-2018 THITH_06565 3d2020cd4d8a3032f7cba9248c81a31a 428 PIRSF PIRSF001529 1 426 1.6E-167 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THITH_06565 3d2020cd4d8a3032f7cba9248c81a31a 428 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 40.146 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THITH_06565 3d2020cd4d8a3032f7cba9248c81a31a 428 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 223 399 2.8E-28 T 13-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_06565 3d2020cd4d8a3032f7cba9248c81a31a 428 SUPERFAMILY SSF55681 116 418 4.7E-95 T 13-10-2018 THITH_06565 3d2020cd4d8a3032f7cba9248c81a31a 428 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 1.2E-157 T 13-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 THITH_06565 3d2020cd4d8a3032f7cba9248c81a31a 428 SUPERFAMILY SSF46589 1 112 9.94E-31 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 THITH_06565 3d2020cd4d8a3032f7cba9248c81a31a 428 Gene3D G3DSA:1.10.287.40 1 104 5.6E-22 T 13-10-2018 THITH_16565 f4b3400ba56296a33f87d0bddef2e75d 502 SUPERFAMILY SSF52540 188 500 2.56E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16565 f4b3400ba56296a33f87d0bddef2e75d 502 Gene3D G3DSA:3.40.50.300 189 496 2.2E-58 T 13-10-2018 THITH_16565 f4b3400ba56296a33f87d0bddef2e75d 502 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 402 494 2.0E-28 T 13-10-2018 IPR025158 Mg chelatase-related protein, C-terminal domain THITH_16565 f4b3400ba56296a33f87d0bddef2e75d 502 Pfam PF01078 Magnesium chelatase, subunit ChlI 188 392 8.2E-95 T 13-10-2018 IPR000523 Magnesium chelatase ChlI domain THITH_16565 f4b3400ba56296a33f87d0bddef2e75d 502 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 138 1.7E-41 T 13-10-2018 THITH_16565 f4b3400ba56296a33f87d0bddef2e75d 502 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 8 494 4.7E-185 T 13-10-2018 IPR004482 Mg chelatase-related protein THITH_16565 f4b3400ba56296a33f87d0bddef2e75d 502 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 287 301 4.7E-7 T 13-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 THITH_16565 f4b3400ba56296a33f87d0bddef2e75d 502 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 207 222 4.7E-7 T 13-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 THITH_16565 f4b3400ba56296a33f87d0bddef2e75d 502 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 315 328 4.7E-7 T 13-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 THITH_16565 f4b3400ba56296a33f87d0bddef2e75d 502 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 339 351 4.7E-7 T 13-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 THITH_16565 f4b3400ba56296a33f87d0bddef2e75d 502 SUPERFAMILY SSF54211 10 169 4.55E-29 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_16565 f4b3400ba56296a33f87d0bddef2e75d 502 SMART SM00382 208 390 1.3E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_14000 df98ca35e916eb9e6d340e05b20cbaec 289 Pfam PF02629 CoA binding domain 6 99 9.5E-30 T 13-10-2018 IPR003781 CoA-binding GO:0048037 THITH_14000 df98ca35e916eb9e6d340e05b20cbaec 289 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 287 1.6E-141 T 13-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THITH_14000 df98ca35e916eb9e6d340e05b20cbaec 289 Pfam PF00549 CoA-ligase 151 270 1.2E-18 T 13-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THITH_14000 df98ca35e916eb9e6d340e05b20cbaec 289 SUPERFAMILY SSF52210 123 286 9.42E-56 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THITH_14000 df98ca35e916eb9e6d340e05b20cbaec 289 PIRSF PIRSF001553 1 289 7.1E-133 T 13-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THITH_14000 df98ca35e916eb9e6d340e05b20cbaec 289 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 2.3E-38 T 13-10-2018 THITH_14000 df98ca35e916eb9e6d340e05b20cbaec 289 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 2.3E-38 T 13-10-2018 THITH_14000 df98ca35e916eb9e6d340e05b20cbaec 289 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 2.3E-38 T 13-10-2018 THITH_14000 df98ca35e916eb9e6d340e05b20cbaec 289 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 2.3E-38 T 13-10-2018 THITH_14000 df98ca35e916eb9e6d340e05b20cbaec 289 SUPERFAMILY SSF51735 1 122 3.2E-42 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_14000 df98ca35e916eb9e6d340e05b20cbaec 289 Gene3D G3DSA:3.40.50.261 124 288 1.9E-72 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THITH_14000 df98ca35e916eb9e6d340e05b20cbaec 289 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 42.948 T 13-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THITH_14000 df98ca35e916eb9e6d340e05b20cbaec 289 SMART SM00881 4 100 9.2E-35 T 13-10-2018 IPR003781 CoA-binding GO:0048037 THITH_14000 df98ca35e916eb9e6d340e05b20cbaec 289 Gene3D G3DSA:3.40.50.720 1 123 1.9E-51 T 13-10-2018 THITH_14000 df98ca35e916eb9e6d340e05b20cbaec 289 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 13-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site THITH_14000 df98ca35e916eb9e6d340e05b20cbaec 289 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 13-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site THITH_13880 8436f076558b528c5888a2c162afaabb 789 SMART SM00316 652 723 2.2E-27 T 13-10-2018 IPR022967 RNA-binding domain, S1 THITH_13880 8436f076558b528c5888a2c162afaabb 789 SUPERFAMILY SSF47781 563 635 1.11E-18 T 13-10-2018 IPR010994 RuvA domain 2-like THITH_13880 8436f076558b528c5888a2c162afaabb 789 Pfam PF12836 Helix-hairpin-helix motif 494 558 1.6E-26 T 13-10-2018 THITH_13880 8436f076558b528c5888a2c162afaabb 789 SMART SM00732 328 427 4.0E-32 T 13-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 THITH_13880 8436f076558b528c5888a2c162afaabb 789 Gene3D G3DSA:1.10.3500.10 115 501 5.2E-153 T 13-10-2018 IPR023323 Tex-like domain superfamily THITH_13880 8436f076558b528c5888a2c162afaabb 789 Gene3D G3DSA:2.40.50.140 634 726 2.1E-28 T 13-10-2018 THITH_13880 8436f076558b528c5888a2c162afaabb 789 SUPERFAMILY SSF47781 473 559 9.0E-26 T 13-10-2018 IPR010994 RuvA domain 2-like THITH_13880 8436f076558b528c5888a2c162afaabb 789 SUPERFAMILY SSF158832 6 323 2.22E-118 T 13-10-2018 THITH_13880 8436f076558b528c5888a2c162afaabb 789 Pfam PF00575 S1 RNA binding domain 652 723 1.4E-22 T 13-10-2018 IPR003029 S1 domain GO:0003676 THITH_13880 8436f076558b528c5888a2c162afaabb 789 SUPERFAMILY SSF50249 640 729 3.66E-26 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_13880 8436f076558b528c5888a2c162afaabb 789 Pfam PF16921 Tex protein YqgF-like domain 329 454 2.7E-49 T 13-10-2018 IPR032639 Tex protein, YqgF-like domain THITH_13880 8436f076558b528c5888a2c162afaabb 789 Gene3D G3DSA:1.10.10.650 5 112 2.1E-42 T 13-10-2018 IPR023319 Tex-like protein, HTH domain superfamily THITH_13880 8436f076558b528c5888a2c162afaabb 789 Pfam PF09371 Tex-like protein N-terminal domain 12 195 2.2E-70 T 13-10-2018 IPR018974 Tex-like protein, N-terminal THITH_13880 8436f076558b528c5888a2c162afaabb 789 Gene3D G3DSA:3.30.420.140 327 454 5.2E-153 T 13-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 THITH_13880 8436f076558b528c5888a2c162afaabb 789 Gene3D G3DSA:1.10.150.310 502 633 7.4E-46 T 13-10-2018 THITH_13880 8436f076558b528c5888a2c162afaabb 789 SUPERFAMILY SSF53098 324 472 1.52E-47 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_17375 9ae6712b6a72ef764feb3796cce78a72 188 Pfam PF01066 CDP-alcohol phosphatidyltransferase 6 58 1.5E-6 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THITH_17375 9ae6712b6a72ef764feb3796cce78a72 188 Gene3D G3DSA:1.20.120.1760 1 158 2.9E-6 T 13-10-2018 THITH_01035 f249c2871424e567581b71a942086d66 612 ProSitePatterns PS00786 5'-nucleotidase signature 2. 126 137 - T 13-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_01035 f249c2871424e567581b71a942086d66 612 SUPERFAMILY SSF55816 403 570 2.09E-43 T 13-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_01035 f249c2871424e567581b71a942086d66 612 Pfam PF02872 5'-nucleotidase, C-terminal domain 408 551 1.3E-34 T 13-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_01035 f249c2871424e567581b71a942086d66 612 ProSitePatterns PS00785 5'-nucleotidase signature 1. 36 48 - T 13-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_01035 f249c2871424e567581b71a942086d66 612 SUPERFAMILY SSF56300 34 369 2.01E-73 T 13-10-2018 THITH_01035 f249c2871424e567581b71a942086d66 612 Gene3D G3DSA:3.60.21.10 25 377 4.0E-100 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like THITH_01035 f249c2871424e567581b71a942086d66 612 Gene3D G3DSA:3.90.780.10 390 586 1.3E-56 T 13-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_01035 f249c2871424e567581b71a942086d66 612 Pfam PF00149 Calcineurin-like phosphoesterase 36 265 3.2E-7 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THITH_01035 f249c2871424e567581b71a942086d66 612 PRINTS PR01607 Apyrase family signature 248 271 2.0E-34 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_01035 f249c2871424e567581b71a942086d66 612 PRINTS PR01607 Apyrase family signature 34 52 2.0E-34 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_01035 f249c2871424e567581b71a942086d66 612 PRINTS PR01607 Apyrase family signature 229 246 2.0E-34 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_01035 f249c2871424e567581b71a942086d66 612 PRINTS PR01607 Apyrase family signature 525 544 2.0E-34 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_01035 f249c2871424e567581b71a942086d66 612 PRINTS PR01607 Apyrase family signature 446 469 2.0E-34 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_01035 f249c2871424e567581b71a942086d66 612 PRINTS PR01607 Apyrase family signature 296 316 2.0E-34 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 SUPERFAMILY SSF50249 429 534 6.49E-21 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_07970 0d4e22d256a6209544876038ae87ea33 557 Gene3D G3DSA:2.40.50.140 445 527 4.5E-19 T 13-10-2018 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 Gene3D G3DSA:2.40.50.140 6 99 4.2E-15 T 13-10-2018 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 Gene3D G3DSA:2.40.50.140 100 183 9.3E-6 T 13-10-2018 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 SUPERFAMILY SSF50249 343 441 7.15E-25 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_07970 0d4e22d256a6209544876038ae87ea33 557 Pfam PF00575 S1 RNA binding domain 361 434 2.8E-19 T 13-10-2018 IPR003029 S1 domain GO:0003676 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 Pfam PF00575 S1 RNA binding domain 104 171 3.4E-9 T 13-10-2018 IPR003029 S1 domain GO:0003676 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 Pfam PF00575 S1 RNA binding domain 190 260 3.5E-21 T 13-10-2018 IPR003029 S1 domain GO:0003676 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 Pfam PF00575 S1 RNA binding domain 276 347 2.5E-19 T 13-10-2018 IPR003029 S1 domain GO:0003676 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 Pfam PF00575 S1 RNA binding domain 447 520 3.9E-16 T 13-10-2018 IPR003029 S1 domain GO:0003676 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 Gene3D G3DSA:2.40.50.140 358 444 6.7E-27 T 13-10-2018 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 Gene3D G3DSA:2.40.50.140 269 357 1.6E-29 T 13-10-2018 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 Gene3D G3DSA:2.40.50.140 187 268 8.2E-27 T 13-10-2018 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 TIGRFAM TIGR00717 rpsA: ribosomal protein bS1 3 520 3.1E-215 T 13-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 PIRSF PIRSF002111 364 543 3.9E-47 T 13-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 PIRSF PIRSF002111 1 386 2.8E-178 T 13-10-2018 IPR000110 Ribosomal protein S1 GO:0003723|GO:0003735|GO:0005840|GO:0006412 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 SMART SM00316 449 520 4.8E-18 T 13-10-2018 IPR022967 RNA-binding domain, S1 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 SMART SM00316 362 434 1.7E-24 T 13-10-2018 IPR022967 RNA-binding domain, S1 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 SMART SM00316 275 347 8.4E-25 T 13-10-2018 IPR022967 RNA-binding domain, S1 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 SMART SM00316 103 171 1.6E-7 T 13-10-2018 IPR022967 RNA-binding domain, S1 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 SMART SM00316 19 87 1.7E-4 T 13-10-2018 IPR022967 RNA-binding domain, S1 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 SMART SM00316 190 260 9.8E-28 T 13-10-2018 IPR022967 RNA-binding domain, S1 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 SUPERFAMILY SSF50249 255 357 2.07E-27 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_07970 0d4e22d256a6209544876038ae87ea33 557 PRINTS PR00681 Ribosomal protein S1 signature 39 53 3.6E-85 T 13-10-2018 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 PRINTS PR00681 Ribosomal protein S1 signature 290 309 3.6E-85 T 13-10-2018 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 PRINTS PR00681 Ribosomal protein S1 signature 126 143 3.6E-85 T 13-10-2018 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 PRINTS PR00681 Ribosomal protein S1 signature 330 348 3.6E-85 T 13-10-2018 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 PRINTS PR00681 Ribosomal protein S1 signature 108 124 3.6E-85 T 13-10-2018 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 PRINTS PR00681 Ribosomal protein S1 signature 84 103 3.6E-85 T 13-10-2018 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 PRINTS PR00681 Ribosomal protein S1 signature 155 175 3.6E-85 T 13-10-2018 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 PRINTS PR00681 Ribosomal protein S1 signature 212 233 3.6E-85 T 13-10-2018 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 PRINTS PR00681 Ribosomal protein S1 signature 21 39 3.6E-85 T 13-10-2018 THITH_07970 0d4e22d256a6209544876038ae87ea33 557 SUPERFAMILY SSF50249 190 277 7.38E-26 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_07970 0d4e22d256a6209544876038ae87ea33 557 SUPERFAMILY SSF50249 103 185 3.23E-13 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_07970 0d4e22d256a6209544876038ae87ea33 557 SUPERFAMILY SSF50249 2 112 1.04E-16 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_08055 dcc7c6a072c26874f9cbc1159e83dfda 121 Gene3D G3DSA:1.10.287.1080 2 109 3.0E-35 T 13-10-2018 THITH_08055 dcc7c6a072c26874f9cbc1159e83dfda 121 SUPERFAMILY SSF101386 3 116 3.2E-36 T 13-10-2018 THITH_08055 dcc7c6a072c26874f9cbc1159e83dfda 121 PIRSF PIRSF029826 2 117 7.8E-44 T 13-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 THITH_08055 dcc7c6a072c26874f9cbc1159e83dfda 121 Pfam PF12643 MazG-like family 37 116 1.9E-16 T 13-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 THITH_14620 881b1955f2bb89bbef66368c62a92289 277 SMART SM00382 36 225 9.7E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_14620 881b1955f2bb89bbef66368c62a92289 277 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_14620 881b1955f2bb89bbef66368c62a92289 277 SUPERFAMILY SSF52540 10 241 6.12E-64 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14620 881b1955f2bb89bbef66368c62a92289 277 Pfam PF00005 ABC transporter 28 176 3.0E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_14620 881b1955f2bb89bbef66368c62a92289 277 Gene3D G3DSA:3.40.50.300 12 253 6.5E-66 T 13-10-2018 THITH_12945 67a5b2f10bc598c1537d39cbef22d7ab 214 Gene3D G3DSA:1.20.120.1200 5 163 1.2E-43 T 13-10-2018 THITH_12945 67a5b2f10bc598c1537d39cbef22d7ab 214 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 18 161 6.9E-36 T 13-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_14575 720d4f2b4c31baf84664d59ab0134a90 361 Gene3D G3DSA:3.40.640.10 49 262 2.0E-101 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_14575 720d4f2b4c31baf84664d59ab0134a90 361 SUPERFAMILY SSF53383 17 357 3.32E-68 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_14575 720d4f2b4c31baf84664d59ab0134a90 361 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 7 357 50.81 T 13-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 THITH_14575 720d4f2b4c31baf84664d59ab0134a90 361 Gene3D G3DSA:3.90.1150.10 16 352 2.0E-101 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_14575 720d4f2b4c31baf84664d59ab0134a90 361 Pfam PF00155 Aminotransferase class I and II 81 353 4.6E-37 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THITH_09890 816289ca53ec628f669b243ba93d92d7 374 SUPERFAMILY SSF53756 19 373 1.82E-70 T 13-10-2018 THITH_09890 816289ca53ec628f669b243ba93d92d7 374 Pfam PF00534 Glycosyl transferases group 1 191 350 5.1E-25 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 THITH_09890 816289ca53ec628f669b243ba93d92d7 374 Gene3D G3DSA:3.40.50.2000 8 370 1.2E-59 T 13-10-2018 THITH_09890 816289ca53ec628f669b243ba93d92d7 374 Pfam PF13439 Glycosyltransferase Family 4 69 176 5.0E-15 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 THITH_09890 816289ca53ec628f669b243ba93d92d7 374 Gene3D G3DSA:3.40.50.2000 174 354 1.2E-59 T 13-10-2018 THITH_03570 f47257df3f806a8ee73cc431de237d9f 590 SUPERFAMILY SSF56300 38 374 2.0E-72 T 13-10-2018 THITH_03570 f47257df3f806a8ee73cc431de237d9f 590 Gene3D G3DSA:3.60.21.10 100 377 2.4E-70 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like THITH_03570 f47257df3f806a8ee73cc431de237d9f 590 TIGRFAM TIGR04486 thiosulf_SoxB: thiosulfohydrolase SoxB 4 576 3.5E-244 T 13-10-2018 IPR030998 Thiosulfohydrolase SoxB THITH_03570 f47257df3f806a8ee73cc431de237d9f 590 PRINTS PR01607 Apyrase family signature 40 58 1.8E-10 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_03570 f47257df3f806a8ee73cc431de237d9f 590 PRINTS PR01607 Apyrase family signature 267 284 1.8E-10 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_03570 f47257df3f806a8ee73cc431de237d9f 590 PRINTS PR01607 Apyrase family signature 286 309 1.8E-10 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_03570 f47257df3f806a8ee73cc431de237d9f 590 PRINTS PR01607 Apyrase family signature 319 339 1.8E-10 T 13-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_03570 f47257df3f806a8ee73cc431de237d9f 590 Pfam PF02872 5'-nucleotidase, C-terminal domain 409 534 1.1E-13 T 13-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_03570 f47257df3f806a8ee73cc431de237d9f 590 SUPERFAMILY SSF55816 389 574 7.85E-32 T 13-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_03570 f47257df3f806a8ee73cc431de237d9f 590 Gene3D G3DSA:3.90.780.10 392 585 2.0E-71 T 13-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 Gene3D G3DSA:1.10.520.10 18 430 9.8E-214 T 13-10-2018 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 Gene3D G3DSA:1.10.420.10 576 697 1.2E-147 T 13-10-2018 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 Pfam PF00141 Peroxidase 403 696 2.8E-37 T 13-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 Pfam PF00141 Peroxidase 70 395 1.6E-48 T 13-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 9 723 0.0 T 13-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 Gene3D G3DSA:1.10.520.10 431 721 1.2E-147 T 13-10-2018 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 ProSitePatterns PS00436 Peroxidases active site signature. 88 99 - T 13-10-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 SUPERFAMILY SSF48113 15 429 1.12E-144 T 13-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 PRINTS PR00458 Haem peroxidase superfamily signature 88 102 9.0E-17 T 13-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 PRINTS PR00458 Haem peroxidase superfamily signature 148 165 9.0E-17 T 13-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 PRINTS PR00458 Haem peroxidase superfamily signature 166 178 9.0E-17 T 13-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 PRINTS PR00458 Haem peroxidase superfamily signature 257 272 9.0E-17 T 13-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 PRINTS PR00458 Haem peroxidase superfamily signature 316 331 9.0E-17 T 13-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 SUPERFAMILY SSF48113 430 721 1.28E-113 T 13-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 24 46 2.2E-53 T 13-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 265 288 2.2E-53 T 13-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 50 63 2.2E-53 T 13-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 65 90 2.2E-53 T 13-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 476 502 2.2E-53 T 13-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 Hamap MF_01961 Catalase-peroxidase [katG]. 5 722 39.53 T 13-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 THITH_16850 fe87e8cb7bdfb9930a70fe11faba2f81 726 Gene3D G3DSA:1.10.420.20 189 397 9.8E-214 T 13-10-2018 THITH_10515 780bea3f5eaa5781318ebeebd28aa054 192 Pfam PF03625 Domain of unknown function DUF302 102 154 2.0E-5 T 13-10-2018 IPR005180 Domain of unknown function DUF302 THITH_10515 780bea3f5eaa5781318ebeebd28aa054 192 SUPERFAMILY SSF103247 61 187 3.79E-19 T 13-10-2018 IPR035923 TT1751-like domain superfamily THITH_16620 19791ca4307c829f88d83de57abad367 90 Gene3D G3DSA:1.10.260.40 1 86 2.3E-29 T 13-10-2018 THITH_16620 19791ca4307c829f88d83de57abad367 90 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 3 86 9.2E-30 T 13-10-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 THITH_16620 19791ca4307c829f88d83de57abad367 90 Pfam PF01381 Helix-turn-helix 20 64 9.8E-7 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_16620 19791ca4307c829f88d83de57abad367 90 SUPERFAMILY SSF47413 8 87 4.86E-20 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 THITH_09630 be462166a0be40216b4c9955df7ae04d 84 TIGRFAM TIGR01215 minE: cell division topological specificity factor MinE 1 82 2.0E-29 T 13-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 THITH_09630 be462166a0be40216b4c9955df7ae04d 84 Hamap MF_00262 Cell division topological specificity factor [minE]. 3 83 17.989 T 13-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 THITH_09630 be462166a0be40216b4c9955df7ae04d 84 Gene3D G3DSA:3.30.1070.10 1 82 2.4E-28 T 13-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 THITH_09630 be462166a0be40216b4c9955df7ae04d 84 Pfam PF03776 Septum formation topological specificity factor MinE 14 81 9.9E-25 T 13-10-2018 IPR005527 Cell division topological specificity factor MinE GO:0032955|GO:0051301 THITH_09630 be462166a0be40216b4c9955df7ae04d 84 SUPERFAMILY SSF55229 33 83 3.01E-15 T 13-10-2018 IPR036707 Cell division topological specificity factor MinE superfamily GO:0032955|GO:0051301 THITH_12860 6d108e3ca914033367e90e8a6078203d 652 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 33 87 7.8E-18 T 13-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 THITH_12860 6d108e3ca914033367e90e8a6078203d 652 Gene3D G3DSA:3.40.50.12780 59 520 3.1E-110 T 13-10-2018 THITH_12860 6d108e3ca914033367e90e8a6078203d 652 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 30 649 5.1E-299 T 13-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 THITH_12860 6d108e3ca914033367e90e8a6078203d 652 SUPERFAMILY SSF56801 34 629 2.22E-174 T 13-10-2018 THITH_12860 6d108e3ca914033367e90e8a6078203d 652 ProSitePatterns PS00455 Putative AMP-binding domain signature. 265 276 - T 13-10-2018 IPR020845 AMP-binding, conserved site THITH_12860 6d108e3ca914033367e90e8a6078203d 652 Gene3D G3DSA:3.30.300.30 523 652 5.7E-30 T 13-10-2018 THITH_12860 6d108e3ca914033367e90e8a6078203d 652 Pfam PF13193 AMP-binding enzyme C-terminal domain 536 617 6.0E-28 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain THITH_12860 6d108e3ca914033367e90e8a6078203d 652 Pfam PF00501 AMP-binding enzyme 90 527 1.5E-95 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 THITH_12860 6d108e3ca914033367e90e8a6078203d 652 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 10 652 51.337 T 13-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 THITH_10230 cc16dcf580a8656d603576be5b6ecf42 289 Gene3D G3DSA:3.90.25.10 159 279 9.1E-102 T 13-10-2018 THITH_10230 cc16dcf580a8656d603576be5b6ecf42 289 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 2 284 3.0E-102 T 13-10-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 THITH_10230 cc16dcf580a8656d603576be5b6ecf42 289 Gene3D G3DSA:3.40.50.720 3 272 9.1E-102 T 13-10-2018 THITH_10230 cc16dcf580a8656d603576be5b6ecf42 289 Pfam PF04321 RmlD substrate binding domain 1 284 1.3E-102 T 13-10-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 THITH_10230 cc16dcf580a8656d603576be5b6ecf42 289 SUPERFAMILY SSF51735 1 284 2.3E-99 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_12265 8c02902233cc28d7914dee12995eddc2 772 SUPERFAMILY SSF53955 156 359 2.81E-65 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily THITH_12265 8c02902233cc28d7914dee12995eddc2 772 TIGRFAM TIGR02071 PBP_1b: penicillin-binding protein 1B 25 750 6.5E-249 T 13-10-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_12265 8c02902233cc28d7914dee12995eddc2 772 PIRSF PIRSF002799 1 772 2.7E-277 T 13-10-2018 IPR011813 Penicillin-binding protein 1B GO:0008233|GO:0008955|GO:0009252|GO:0009274|GO:0046677 KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_12265 8c02902233cc28d7914dee12995eddc2 772 Pfam PF00912 Transglycosylase 164 336 1.6E-58 T 13-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_12265 8c02902233cc28d7914dee12995eddc2 772 SUPERFAMILY SSF56601 317 755 3.94E-108 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like THITH_12265 8c02902233cc28d7914dee12995eddc2 772 Gene3D G3DSA:1.10.3810.10 156 359 4.2E-244 T 13-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_12265 8c02902233cc28d7914dee12995eddc2 772 Gene3D G3DSA:3.30.2060.10 68 155 4.2E-244 T 13-10-2018 THITH_12265 8c02902233cc28d7914dee12995eddc2 772 Pfam PF14814 Bifunctional transglycosylase second domain 70 151 2.1E-20 T 13-10-2018 IPR028166 Bifunctional transglycosylase second domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_12265 8c02902233cc28d7914dee12995eddc2 772 Gene3D G3DSA:3.40.710.10 60 704 4.2E-244 T 13-10-2018 THITH_12265 8c02902233cc28d7914dee12995eddc2 772 Pfam PF00905 Penicillin binding protein transpeptidase domain 430 683 6.9E-20 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THITH_14745 2a664c85802f63d33bfb5015bcf3a3e1 431 SUPERFAMILY SSF51230 3 89 6.89E-21 T 13-10-2018 IPR011053 Single hybrid motif THITH_14745 2a664c85802f63d33bfb5015bcf3a3e1 431 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 THITH_14745 2a664c85802f63d33bfb5015bcf3a3e1 431 Pfam PF00364 Biotin-requiring enzyme 6 77 1.4E-19 T 13-10-2018 IPR000089 Biotin/lipoyl attachment THITH_14745 2a664c85802f63d33bfb5015bcf3a3e1 431 SUPERFAMILY SSF47005 136 176 2.49E-11 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 THITH_14745 2a664c85802f63d33bfb5015bcf3a3e1 431 TIGRFAM TIGR01348 PDHac_trf_long: dihydrolipoyllysine-residue acetyltransferase 4 431 2.5E-181 T 13-10-2018 IPR006256 Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex GO:0004742|GO:0006096|GO:0045254 KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 THITH_14745 2a664c85802f63d33bfb5015bcf3a3e1 431 SUPERFAMILY SSF52777 191 431 5.78E-83 T 13-10-2018 THITH_14745 2a664c85802f63d33bfb5015bcf3a3e1 431 Pfam PF02817 e3 binding domain 138 172 4.2E-15 T 13-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 THITH_14745 2a664c85802f63d33bfb5015bcf3a3e1 431 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 204 431 1.2E-80 T 13-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 THITH_14745 2a664c85802f63d33bfb5015bcf3a3e1 431 Gene3D G3DSA:4.10.320.10 137 181 7.9E-19 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 THITH_14745 2a664c85802f63d33bfb5015bcf3a3e1 431 Gene3D G3DSA:3.30.559.10 187 431 3.9E-94 T 13-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 THITH_14745 2a664c85802f63d33bfb5015bcf3a3e1 431 Gene3D G3DSA:2.40.50.100 3 82 8.3E-21 T 13-10-2018 THITH_04600 2d13af963ba9838a4eb2a009139c8d30 241 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 24 119 2.6E-10 T 13-10-2018 IPR000477 Reverse transcriptase domain THITH_04600 2d13af963ba9838a4eb2a009139c8d30 241 SUPERFAMILY SSF56672 17 180 2.39E-10 T 13-10-2018 THITH_04600 2d13af963ba9838a4eb2a009139c8d30 241 Pfam PF08388 Group II intron, maturase-specific domain 141 209 1.2E-5 T 13-10-2018 IPR013597 Group II intron, maturase-specific THITH_15655 fbd20ee5c1493b4af9f83efdeca698b4 402 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 22 384 1.5E-143 T 13-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 THITH_15655 fbd20ee5c1493b4af9f83efdeca698b4 402 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 239 248 - T 13-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 THITH_15655 fbd20ee5c1493b4af9f83efdeca698b4 402 SUPERFAMILY SSF53383 8 389 1.01E-109 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_15655 fbd20ee5c1493b4af9f83efdeca698b4 402 Gene3D G3DSA:3.90.1150.10 43 382 1.6E-132 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_15655 fbd20ee5c1493b4af9f83efdeca698b4 402 Gene3D G3DSA:3.40.640.10 59 290 1.6E-132 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_15655 fbd20ee5c1493b4af9f83efdeca698b4 402 Hamap MF_01693 8-amino-7-oxononanoate synthase [bioF]. 5 388 49.489 T 13-10-2018 IPR022834 8-amino-7-oxononanoate synthase, Proteobacteria GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 THITH_15655 fbd20ee5c1493b4af9f83efdeca698b4 402 Pfam PF00155 Aminotransferase class I and II 42 384 4.2E-60 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THITH_09995 6a34b5ec77fe47f704a52415ee7aca55 691 Pfam PF13090 Polyphosphate kinase C-terminal domain 336 684 1.2E-152 T 13-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 THITH_09995 6a34b5ec77fe47f704a52415ee7aca55 691 Gene3D G3DSA:3.30.870.10 326 505 5.2E-72 T 13-10-2018 THITH_09995 6a34b5ec77fe47f704a52415ee7aca55 691 Gene3D G3DSA:3.30.1840.10 5 318 3.1E-102 T 13-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 THITH_09995 6a34b5ec77fe47f704a52415ee7aca55 691 SUPERFAMILY SSF140356 8 113 7.85E-38 T 13-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 THITH_09995 6a34b5ec77fe47f704a52415ee7aca55 691 Hamap MF_00347 Polyphosphate kinase [ppk]. 9 689 28.464 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 THITH_09995 6a34b5ec77fe47f704a52415ee7aca55 691 Pfam PF13089 Polyphosphate kinase N-terminal domain 12 117 3.1E-36 T 13-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 THITH_09995 6a34b5ec77fe47f704a52415ee7aca55 691 SUPERFAMILY SSF56024 326 498 3.14E-56 T 13-10-2018 THITH_09995 6a34b5ec77fe47f704a52415ee7aca55 691 Gene3D G3DSA:3.30.870.10 506 691 4.2E-64 T 13-10-2018 THITH_09995 6a34b5ec77fe47f704a52415ee7aca55 691 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 12 685 5.9E-288 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 THITH_09995 6a34b5ec77fe47f704a52415ee7aca55 691 SUPERFAMILY SSF143724 115 320 1.33E-65 T 13-10-2018 THITH_09995 6a34b5ec77fe47f704a52415ee7aca55 691 SUPERFAMILY SSF56024 506 688 4.93E-68 T 13-10-2018 THITH_09995 6a34b5ec77fe47f704a52415ee7aca55 691 Pfam PF02503 Polyphosphate kinase middle domain 126 328 4.5E-61 T 13-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 THITH_09995 6a34b5ec77fe47f704a52415ee7aca55 691 PIRSF PIRSF015589 1 691 6.9E-280 T 13-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 THITH_15500 97b6509bd5c0fd4baff4dd3258383e5a 425 Pfam PF00909 Ammonium Transporter Family 17 418 9.9E-96 T 13-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 THITH_15500 97b6509bd5c0fd4baff4dd3258383e5a 425 Gene3D G3DSA:1.10.3430.10 1 425 3.3E-115 T 13-10-2018 IPR029020 Ammonium/urea transporter THITH_15500 97b6509bd5c0fd4baff4dd3258383e5a 425 TIGRFAM TIGR03644 marine_trans_1: probable ammonium transporter, marine subtype 10 421 1.2E-198 T 13-10-2018 IPR019879 Ammonium transporter, marine subtype THITH_15500 97b6509bd5c0fd4baff4dd3258383e5a 425 SUPERFAMILY SSF111352 10 399 1.7E-101 T 13-10-2018 THITH_15500 97b6509bd5c0fd4baff4dd3258383e5a 425 ProSitePatterns PS01219 Ammonium transporters signature. 179 204 - T 13-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 THITH_08280 28b033794b3ca4bb890ddcec1302075b 1883 Gene3D G3DSA:3.40.50.1820 575 728 5.9E-16 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_08280 28b033794b3ca4bb890ddcec1302075b 1883 Pfam PF12770 CHAT domain 1218 1497 3.1E-33 T 13-10-2018 IPR024983 CHAT domain THITH_08280 28b033794b3ca4bb890ddcec1302075b 1883 SUPERFAMILY SSF53474 554 756 1.54E-15 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_08280 28b033794b3ca4bb890ddcec1302075b 1883 Gene3D G3DSA:3.40.220.10 957 1119 1.7E-5 T 13-10-2018 THITH_08280 28b033794b3ca4bb890ddcec1302075b 1883 Pfam PF02450 Lecithin:cholesterol acyltransferase 617 708 2.6E-7 T 13-10-2018 IPR003386 Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase GO:0006629|GO:0008374 THITH_00100 17aca8b536a364de1c685cce4b088ede 410 Gene3D G3DSA:3.30.420.380 14 159 1.9E-29 T 13-10-2018 THITH_00100 17aca8b536a364de1c685cce4b088ede 410 Pfam PF12693 GspL periplasmic domain 256 381 4.0E-16 T 13-10-2018 IPR025691 GspL periplasmic domain THITH_00100 17aca8b536a364de1c685cce4b088ede 410 PIRSF PIRSF015761 47 408 2.0E-31 T 13-10-2018 IPR007812 Type II secretion system protein L GO:0008565|GO:0009276|GO:0015031|GO:0016021 THITH_00100 17aca8b536a364de1c685cce4b088ede 410 SUPERFAMILY SSF53067 3 143 1.68E-23 T 13-10-2018 THITH_00100 17aca8b536a364de1c685cce4b088ede 410 Pfam PF05134 Type II secretion system (T2SS), protein L 49 247 8.1E-24 T 13-10-2018 IPR024230 GspL, cytoplasmic actin-ATPase-like domain THITH_13435 a8f724007984105225e4f9de2d30c849 213 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 17 207 1.6E-102 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THITH_13435 a8f724007984105225e4f9de2d30c849 213 PRINTS PR00127 Clp protease catalytic subunit P signature 105 122 6.7E-51 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THITH_13435 a8f724007984105225e4f9de2d30c849 213 PRINTS PR00127 Clp protease catalytic subunit P signature 126 145 6.7E-51 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THITH_13435 a8f724007984105225e4f9de2d30c849 213 PRINTS PR00127 Clp protease catalytic subunit P signature 34 49 6.7E-51 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THITH_13435 a8f724007984105225e4f9de2d30c849 213 PRINTS PR00127 Clp protease catalytic subunit P signature 74 94 6.7E-51 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THITH_13435 a8f724007984105225e4f9de2d30c849 213 PRINTS PR00127 Clp protease catalytic subunit P signature 183 202 6.7E-51 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THITH_13435 a8f724007984105225e4f9de2d30c849 213 SUPERFAMILY SSF52096 26 209 2.33E-72 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THITH_13435 a8f724007984105225e4f9de2d30c849 213 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 18 208 43.469 T 13-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 THITH_13435 a8f724007984105225e4f9de2d30c849 213 Gene3D G3DSA:3.90.226.10 7 212 1.5E-82 T 13-10-2018 THITH_13435 a8f724007984105225e4f9de2d30c849 213 Pfam PF00574 Clp protease 28 207 1.0E-85 T 13-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA THITH_13435 a8f724007984105225e4f9de2d30c849 213 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 105 116 - T 13-10-2018 IPR018215 ClpP, Ser active site THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 422 6.9E-197 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 Pfam PF03952 Enolase, N-terminal domain 4 131 1.1E-50 T 13-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 SMART SM01192 137 423 4.5E-215 T 13-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 SUPERFAMILY SSF54826 3 136 3.72E-47 T 13-10-2018 THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 ProSitePatterns PS00164 Enolase signature. 332 345 - T 13-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 139 421 3.5E-127 T 13-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 PRINTS PR00148 Enolase signature 159 172 2.0E-44 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 PRINTS PR00148 Enolase signature 37 51 2.0E-44 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 PRINTS PR00148 Enolase signature 309 320 2.0E-44 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 PRINTS PR00148 Enolase signature 105 121 2.0E-44 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 PRINTS PR00148 Enolase signature 332 346 2.0E-44 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 PRINTS PR00148 Enolase signature 361 378 2.0E-44 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 SUPERFAMILY SSF51604 139 421 6.93E-124 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 PIRSF PIRSF001400 1 423 3.6E-177 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 Gene3D G3DSA:3.20.20.120 126 427 6.3E-125 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 Gene3D G3DSA:3.30.390.10 1 125 2.4E-48 T 13-10-2018 IPR029017 Enolase-like, N-terminal THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 SMART SM01193 4 132 3.1E-76 T 13-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_07085 2622f1afc8c1854f19e78f338e5c4940 428 Hamap MF_00318 Enolase [eno]. 2 409 43.04 T 13-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_06255 2ab3b7197cbfeff7a509dfd4c7a00905 118 SMART SM00422 19 89 5.4E-11 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THITH_06255 2ab3b7197cbfeff7a509dfd4c7a00905 118 Pfam PF13411 MerR HTH family regulatory protein 19 87 1.4E-23 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THITH_06255 2ab3b7197cbfeff7a509dfd4c7a00905 118 Gene3D G3DSA:1.10.1660.10 14 89 1.4E-22 T 13-10-2018 THITH_06255 2ab3b7197cbfeff7a509dfd4c7a00905 118 SUPERFAMILY SSF46955 19 117 5.95E-20 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily THITH_00820 a256560bc2d1a904e8df6da3f640474e 806 Gene3D G3DSA:3.40.50.300 48 256 3.5E-45 T 13-10-2018 THITH_00820 a256560bc2d1a904e8df6da3f640474e 806 Pfam PF09369 Domain of unknown function (DUF1998) 666 772 3.5E-14 T 13-10-2018 IPR018973 DEAD/DEAH-box helicase, putative THITH_00820 a256560bc2d1a904e8df6da3f640474e 806 Gene3D G3DSA:3.40.50.300 284 488 1.2E-23 T 13-10-2018 THITH_00820 a256560bc2d1a904e8df6da3f640474e 806 Pfam PF00270 DEAD/DEAH box helicase 72 240 2.3E-25 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THITH_00820 a256560bc2d1a904e8df6da3f640474e 806 SMART SM00487 66 270 8.9E-28 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_00820 a256560bc2d1a904e8df6da3f640474e 806 SMART SM00490 312 404 3.8E-16 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_00820 a256560bc2d1a904e8df6da3f640474e 806 SUPERFAMILY SSF52540 79 410 1.05E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00820 a256560bc2d1a904e8df6da3f640474e 806 Pfam PF00271 Helicase conserved C-terminal domain 299 403 3.7E-14 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_00705 bccd3b3fbb5521f795d723b0a01dc565 367 Pfam PF00990 Diguanylate cyclase, GGDEF domain 198 354 1.9E-45 T 13-10-2018 IPR000160 GGDEF domain THITH_00705 bccd3b3fbb5521f795d723b0a01dc565 367 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 193 356 7.4E-50 T 13-10-2018 IPR000160 GGDEF domain THITH_00705 bccd3b3fbb5521f795d723b0a01dc565 367 Gene3D G3DSA:3.30.70.270 192 361 6.8E-58 T 13-10-2018 THITH_00705 bccd3b3fbb5521f795d723b0a01dc565 367 SUPERFAMILY SSF55073 202 359 2.98E-49 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_00705 bccd3b3fbb5521f795d723b0a01dc565 367 SMART SM00267 186 358 1.7E-58 T 13-10-2018 IPR000160 GGDEF domain THITH_05050 c3710bfcfe96173ba7ef842422ce7be4 449 Gene3D G3DSA:1.10.10.60 393 437 1.9E-11 T 13-10-2018 THITH_05050 c3710bfcfe96173ba7ef842422ce7be4 449 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 348 357 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site THITH_05050 c3710bfcfe96173ba7ef842422ce7be4 449 SUPERFAMILY SSF46689 349 438 2.51E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_05050 c3710bfcfe96173ba7ef842422ce7be4 449 Pfam PF08448 PAS fold 19 126 3.4E-8 T 13-10-2018 IPR013656 PAS fold-4 THITH_05050 c3710bfcfe96173ba7ef842422ce7be4 449 SMART SM00382 158 305 1.9E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_05050 c3710bfcfe96173ba7ef842422ce7be4 449 Pfam PF00158 Sigma-54 interaction domain 138 304 2.0E-64 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THITH_05050 c3710bfcfe96173ba7ef842422ce7be4 449 SUPERFAMILY SSF55785 17 123 1.21E-5 T 13-10-2018 IPR035965 PAS domain superfamily THITH_05050 c3710bfcfe96173ba7ef842422ce7be4 449 Pfam PF02954 Bacterial regulatory protein, Fis family 398 438 5.8E-10 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_05050 c3710bfcfe96173ba7ef842422ce7be4 449 SUPERFAMILY SSF52540 138 376 9.13E-67 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_05050 c3710bfcfe96173ba7ef842422ce7be4 449 Gene3D G3DSA:1.10.8.60 309 384 7.3E-20 T 13-10-2018 THITH_05050 c3710bfcfe96173ba7ef842422ce7be4 449 Gene3D G3DSA:3.40.50.300 124 308 5.8E-63 T 13-10-2018 THITH_05050 c3710bfcfe96173ba7ef842422ce7be4 449 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 162 175 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THITH_07515 24cce188c2cae891788a2cfdb6857074 916 Pfam PF00384 Molybdopterin oxidoreductase 100 613 3.7E-76 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_07515 24cce188c2cae891788a2cfdb6857074 916 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 44 96 2.5E-16 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_07515 24cce188c2cae891788a2cfdb6857074 916 SUPERFAMILY SSF50692 782 916 5.18E-38 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily THITH_07515 24cce188c2cae891788a2cfdb6857074 916 Gene3D G3DSA:2.40.40.20 792 916 2.1E-41 T 13-10-2018 THITH_07515 24cce188c2cae891788a2cfdb6857074 916 SUPERFAMILY SSF53706 40 620 4.97E-164 T 13-10-2018 THITH_07515 24cce188c2cae891788a2cfdb6857074 916 Hamap MF_01630 Periplasmic nitrate reductase [napA]. 1 916 30.155 T 13-10-2018 IPR010051 Periplasmic nitrate reductase, large subunit GO:0008940|GO:0030151|GO:0042597|GO:0055114 KEGG: 00910+1.9.6.1|MetaCyc: PWY-5674 THITH_07515 24cce188c2cae891788a2cfdb6857074 916 Pfam PF01568 Molydopterin dinucleotide binding domain 802 908 2.1E-25 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 THITH_07515 24cce188c2cae891788a2cfdb6857074 916 TIGRFAM TIGR01706 NAPA: periplasmic nitrate reductase, large subunit 3 916 0.0 T 13-10-2018 IPR010051 Periplasmic nitrate reductase, large subunit GO:0008940|GO:0030151|GO:0042597|GO:0055114 KEGG: 00910+1.9.6.1|MetaCyc: PWY-5674 THITH_07515 24cce188c2cae891788a2cfdb6857074 916 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 65 - T 13-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 THITH_07515 24cce188c2cae891788a2cfdb6857074 916 SMART SM00926 43 97 8.5E-15 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_16940 227c0f83da66ab9a95cf970a3d12a6ad 129 SUPERFAMILY SSF55298 1 127 2.36E-45 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 THITH_16940 227c0f83da66ab9a95cf970a3d12a6ad 129 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 102 120 - T 13-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 THITH_16940 227c0f83da66ab9a95cf970a3d12a6ad 129 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 4 124 1.3E-48 T 13-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 THITH_16940 227c0f83da66ab9a95cf970a3d12a6ad 129 Gene3D G3DSA:3.30.1330.40 1 128 4.9E-51 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 THITH_16940 227c0f83da66ab9a95cf970a3d12a6ad 129 Pfam PF01042 Endoribonuclease L-PSP 9 124 4.2E-40 T 13-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 THITH_12645 cff79550bab6751ea9df79edf6492e5f 371 Gene3D G3DSA:3.40.50.720 130 305 7.6E-139 T 13-10-2018 THITH_12645 cff79550bab6751ea9df79edf6492e5f 371 SMART SM01002 149 297 3.7E-81 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain THITH_12645 cff79550bab6751ea9df79edf6492e5f 371 SMART SM01003 4 137 1.2E-77 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal THITH_12645 cff79550bab6751ea9df79edf6492e5f 371 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 3.7E-159 T 13-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 THITH_12645 cff79550bab6751ea9df79edf6492e5f 371 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 142 352 3.0E-78 T 13-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain THITH_12645 cff79550bab6751ea9df79edf6492e5f 371 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 13-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 THITH_12645 cff79550bab6751ea9df79edf6492e5f 371 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 1.8E-46 T 13-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal THITH_12645 cff79550bab6751ea9df79edf6492e5f 371 SUPERFAMILY SSF51735 137 303 9.72E-50 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_12645 cff79550bab6751ea9df79edf6492e5f 371 SUPERFAMILY SSF52283 1 360 4.59E-65 T 13-10-2018 THITH_12645 cff79550bab6751ea9df79edf6492e5f 371 Gene3D G3DSA:3.40.50.720 3 353 7.6E-139 T 13-10-2018 THITH_12645 cff79550bab6751ea9df79edf6492e5f 371 PIRSF PIRSF000183 1 371 1.6E-155 T 13-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 THITH_14885 d7f92cbbfa801e7b5fa6fbe5884078b2 193 Gene3D G3DSA:3.30.70.60 94 193 5.4E-34 T 13-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 THITH_14885 d7f92cbbfa801e7b5fa6fbe5884078b2 193 Pfam PF04350 Pilus assembly protein, PilO 49 191 4.5E-48 T 13-10-2018 IPR007445 Pilus assembly protein, PilO THITH_14885 d7f92cbbfa801e7b5fa6fbe5884078b2 193 Gene3D G3DSA:1.10.287.540 57 92 3.7E-8 T 13-10-2018 THITH_14885 d7f92cbbfa801e7b5fa6fbe5884078b2 193 PIRSF PIRSF016482 1 193 1.5E-55 T 13-10-2018 IPR007445 Pilus assembly protein, PilO THITH_05455 83459ef40c81861ac36d8c56d5c50d20 593 SMART SM00382 379 565 2.6E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_05455 83459ef40c81861ac36d8c56d5c50d20 593 Gene3D G3DSA:1.20.1560.10 16 332 4.2E-76 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THITH_05455 83459ef40c81861ac36d8c56d5c50d20 593 Pfam PF00664 ABC transporter transmembrane region 35 303 1.8E-48 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 THITH_05455 83459ef40c81861ac36d8c56d5c50d20 593 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_05455 83459ef40c81861ac36d8c56d5c50d20 593 Pfam PF00005 ABC transporter 370 519 5.4E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_05455 83459ef40c81861ac36d8c56d5c50d20 593 SUPERFAMILY SSF90123 23 332 1.06E-71 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THITH_05455 83459ef40c81861ac36d8c56d5c50d20 593 SUPERFAMILY SSF52540 343 590 1.11E-88 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_05455 83459ef40c81861ac36d8c56d5c50d20 593 Gene3D G3DSA:3.40.50.300 343 592 9.4E-95 T 13-10-2018 THITH_05430 8a38cb50f2ef8c97dc994f2b70d2de77 754 Pfam PF02769 AIR synthase related protein, C-terminal domain 571 745 7.8E-23 T 13-10-2018 IPR010918 PurM-like, C-terminal domain THITH_05430 8a38cb50f2ef8c97dc994f2b70d2de77 754 Gene3D G3DSA:3.30.1330.10 397 564 2.4E-39 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THITH_05430 8a38cb50f2ef8c97dc994f2b70d2de77 754 Pfam PF00586 AIR synthase related protein, N-terminal domain 450 559 3.2E-10 T 13-10-2018 IPR016188 PurM-like, N-terminal domain THITH_05430 8a38cb50f2ef8c97dc994f2b70d2de77 754 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 8.9E-9 T 13-10-2018 THITH_05430 8a38cb50f2ef8c97dc994f2b70d2de77 754 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 277 299 8.9E-9 T 13-10-2018 THITH_05430 8a38cb50f2ef8c97dc994f2b70d2de77 754 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 8.9E-9 T 13-10-2018 THITH_05430 8a38cb50f2ef8c97dc994f2b70d2de77 754 TIGRFAM TIGR03169 Nterm_to_SelD: pyridine nucleotide-disulfide oxidoreductase family protein 11 381 4.0E-154 T 13-10-2018 IPR017584 Pyridine nucleotide-disulphide oxidoreductase family protein, N-terminal THITH_05430 8a38cb50f2ef8c97dc994f2b70d2de77 754 TIGRFAM TIGR00476 selD: selenide, water dikinase 413 718 5.8E-91 T 13-10-2018 IPR004536 Selenophosphate synthetase GO:0005524 KEGG: 00450+2.7.9.3|MetaCyc: PWY-6281 THITH_05430 8a38cb50f2ef8c97dc994f2b70d2de77 754 SUPERFAMILY SSF51905 10 178 2.07E-23 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_05430 8a38cb50f2ef8c97dc994f2b70d2de77 754 SUPERFAMILY SSF51905 156 328 4.18E-25 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_05430 8a38cb50f2ef8c97dc994f2b70d2de77 754 Gene3D G3DSA:3.90.650.10 566 750 6.0E-60 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THITH_05430 8a38cb50f2ef8c97dc994f2b70d2de77 754 SUPERFAMILY SSF56042 565 745 7.92E-45 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THITH_05430 8a38cb50f2ef8c97dc994f2b70d2de77 754 SUPERFAMILY SSF55326 412 563 1.15E-30 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THITH_05430 8a38cb50f2ef8c97dc994f2b70d2de77 754 Gene3D G3DSA:3.50.50.100 9 392 2.0E-84 T 13-10-2018 THITH_05430 8a38cb50f2ef8c97dc994f2b70d2de77 754 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 316 6.9E-31 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THITH_11055 68996f488df9424844d047a5335fb8de 419 Gene3D G3DSA:3.40.50.300 255 389 6.7E-7 T 13-10-2018 THITH_11055 68996f488df9424844d047a5335fb8de 419 Gene3D G3DSA:3.40.50.300 2 141 7.0E-8 T 13-10-2018 THITH_11055 68996f488df9424844d047a5335fb8de 419 SUPERFAMILY SSF52540 2 386 4.25E-18 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_11055 68996f488df9424844d047a5335fb8de 419 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 23 56 1.8E-6 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THITH_11055 68996f488df9424844d047a5335fb8de 419 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 197 370 1.8E-21 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THITH_11055 68996f488df9424844d047a5335fb8de 419 PIRSF PIRSF029347 157 405 7.7E-8 T 13-10-2018 IPR014555 RecF-like THITH_11055 68996f488df9424844d047a5335fb8de 419 PIRSF PIRSF029347 1 132 5.8E-11 T 13-10-2018 IPR014555 RecF-like THITH_04500 c310fd818887008e5453b72f898b7925 84 SUPERFAMILY SSF160443 5 82 2.22E-6 T 13-10-2018 IPR036063 Smr domain superfamily THITH_04500 c310fd818887008e5453b72f898b7925 84 Pfam PF01713 Smr domain 6 83 1.3E-13 T 13-10-2018 IPR002625 Smr domain THITH_04500 c310fd818887008e5453b72f898b7925 84 Gene3D G3DSA:3.30.1370.110 3 83 9.8E-14 T 13-10-2018 THITH_12350 9a75e3169cf6b534d1f3912945b24681 87 ProDom PD012510 UTILIZATION ETHANOLAMINE CARBOXYSOME CCML PEPTIDE EUTN/CARBOXYSOME STRUCTURAL EUTN A B 10 78 2.0E-29 T 13-10-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml THITH_12350 9a75e3169cf6b534d1f3912945b24681 87 SUPERFAMILY SSF159133 1 80 2.35E-23 T 13-10-2018 IPR036677 EutN/Ccml superfamily THITH_12350 9a75e3169cf6b534d1f3912945b24681 87 TIGRFAM TIGR02703 carboxysome_A: carboxysome peptide A 1 78 1.3E-44 T 13-10-2018 IPR014076 Carboxysome peptide A THITH_12350 9a75e3169cf6b534d1f3912945b24681 87 Gene3D G3DSA:2.40.50.220 1 86 5.9E-31 T 13-10-2018 IPR036677 EutN/Ccml superfamily THITH_12350 9a75e3169cf6b534d1f3912945b24681 87 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome 1 76 4.1E-20 T 13-10-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml THITH_16335 512ce2623dcdaec613d98845bee90df2 521 Pfam PF01808 AICARFT/IMPCHase bienzyme 137 452 1.5E-118 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THITH_16335 512ce2623dcdaec613d98845bee90df2 521 Gene3D G3DSA:3.40.50.1380 1 199 4.7E-83 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily THITH_16335 512ce2623dcdaec613d98845bee90df2 521 PIRSF PIRSF000414 1 521 8.4E-218 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THITH_16335 512ce2623dcdaec613d98845bee90df2 521 SMART SM00851 19 132 5.2E-58 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain THITH_16335 512ce2623dcdaec613d98845bee90df2 521 SMART SM00798 137 453 2.1E-197 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THITH_16335 512ce2623dcdaec613d98845bee90df2 521 SUPERFAMILY SSF52335 7 195 1.57E-68 T 13-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily THITH_16335 512ce2623dcdaec613d98845bee90df2 521 SUPERFAMILY SSF53927 214 521 3.01E-126 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 THITH_16335 512ce2623dcdaec613d98845bee90df2 521 Gene3D G3DSA:3.40.140.20 384 521 1.1E-59 T 13-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THITH_16335 512ce2623dcdaec613d98845bee90df2 521 Gene3D G3DSA:3.40.140.20 211 366 1.0E-57 T 13-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THITH_16335 512ce2623dcdaec613d98845bee90df2 521 Pfam PF02142 MGS-like domain 19 131 2.2E-27 T 13-10-2018 IPR011607 Methylglyoxal synthase-like domain THITH_16335 512ce2623dcdaec613d98845bee90df2 521 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 8 521 1.9E-234 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THITH_16335 512ce2623dcdaec613d98845bee90df2 521 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 7 521 44.795 T 13-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THITH_02745 a3143439dccafa9878ae70f47e968f67 383 Pfam PF01594 AI-2E family transporter 19 345 9.1E-69 T 13-10-2018 IPR002549 Transmembrane protein TqsA-like THITH_04065 d0472b227223413d88eba88090a38969 547 Gene3D G3DSA:1.20.1480.50 67 153 1.6E-7 T 13-10-2018 THITH_04065 d0472b227223413d88eba88090a38969 547 SMART SM00387 437 533 8.2E-9 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_04065 d0472b227223413d88eba88090a38969 547 SUPERFAMILY SSF55781 163 324 1.72E-20 T 13-10-2018 THITH_04065 d0472b227223413d88eba88090a38969 547 Pfam PF07730 Histidine kinase 333 398 2.2E-12 T 13-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 THITH_04065 d0472b227223413d88eba88090a38969 547 SMART SM00304 94 146 1.6E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_04065 d0472b227223413d88eba88090a38969 547 Gene3D G3DSA:3.30.565.10 401 530 5.0E-26 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_04065 d0472b227223413d88eba88090a38969 547 PIRSF PIRSF003167 65 541 2.0E-101 T 13-10-2018 IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing GO:0000155|GO:0000160|GO:0004673|GO:0016021 THITH_04065 d0472b227223413d88eba88090a38969 547 SMART SM00065 181 326 5.5E-5 T 13-10-2018 IPR003018 GAF domain GO:0005515 THITH_04065 d0472b227223413d88eba88090a38969 547 SUPERFAMILY SSF55874 398 528 2.19E-16 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_04065 d0472b227223413d88eba88090a38969 547 Pfam PF13185 GAF domain 179 317 1.3E-11 T 13-10-2018 IPR003018 GAF domain GO:0005515 THITH_04065 d0472b227223413d88eba88090a38969 547 Pfam PF00672 HAMP domain 95 143 6.1E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_04065 d0472b227223413d88eba88090a38969 547 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 440 531 2.8E-9 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_04065 d0472b227223413d88eba88090a38969 547 SUPERFAMILY SSF158472 96 144 1.01E-8 T 13-10-2018 THITH_04065 d0472b227223413d88eba88090a38969 547 Gene3D G3DSA:3.30.450.40 160 324 9.8E-26 T 13-10-2018 IPR029016 GAF-like domain superfamily THITH_14105 1c7f5f79509894c39bc047128e3536ce 249 Pfam PF00005 ABC transporter 33 186 3.4E-22 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_14105 1c7f5f79509894c39bc047128e3536ce 249 SMART SM00382 37 241 2.3E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_14105 1c7f5f79509894c39bc047128e3536ce 249 SUPERFAMILY SSF52540 33 234 2.2E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14105 1c7f5f79509894c39bc047128e3536ce 249 Gene3D G3DSA:3.40.50.300 29 249 1.2E-50 T 13-10-2018 THITH_06980 db6064c01bf171705e0e89014901375c 558 SUPERFAMILY SSF141868 304 553 1.57E-87 T 13-10-2018 IPR035919 EAL domain superfamily THITH_06980 db6064c01bf171705e0e89014901375c 558 SMART SM00086 74 116 4.9E-6 T 13-10-2018 IPR001610 PAC motif THITH_06980 db6064c01bf171705e0e89014901375c 558 SMART SM00091 2 69 2.3E-7 T 13-10-2018 IPR000014 PAS domain THITH_06980 db6064c01bf171705e0e89014901375c 558 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 123 287 3.9E-44 T 13-10-2018 IPR000160 GGDEF domain THITH_06980 db6064c01bf171705e0e89014901375c 558 SUPERFAMILY SSF55785 7 114 5.41E-29 T 13-10-2018 IPR035965 PAS domain superfamily THITH_06980 db6064c01bf171705e0e89014901375c 558 Gene3D G3DSA:3.30.450.20 1 130 1.5E-34 T 13-10-2018 THITH_06980 db6064c01bf171705e0e89014901375c 558 Pfam PF00989 PAS fold 8 113 1.3E-15 T 13-10-2018 IPR013767 PAS fold GO:0006355 THITH_06980 db6064c01bf171705e0e89014901375c 558 Pfam PF00563 EAL domain 306 540 7.5E-72 T 13-10-2018 IPR001633 EAL domain THITH_06980 db6064c01bf171705e0e89014901375c 558 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 7 123 9.3E-22 T 13-10-2018 IPR000014 PAS domain THITH_06980 db6064c01bf171705e0e89014901375c 558 SMART SM00052 299 545 1.2E-111 T 13-10-2018 IPR001633 EAL domain THITH_06980 db6064c01bf171705e0e89014901375c 558 Gene3D G3DSA:3.30.70.270 131 300 6.8E-59 T 13-10-2018 THITH_06980 db6064c01bf171705e0e89014901375c 558 Pfam PF00990 Diguanylate cyclase, GGDEF domain 127 285 1.3E-49 T 13-10-2018 IPR000160 GGDEF domain THITH_06980 db6064c01bf171705e0e89014901375c 558 SMART SM00267 116 289 8.4E-69 T 13-10-2018 IPR000160 GGDEF domain THITH_06980 db6064c01bf171705e0e89014901375c 558 Gene3D G3DSA:3.20.20.450 301 553 2.3E-101 T 13-10-2018 IPR035919 EAL domain superfamily THITH_06980 db6064c01bf171705e0e89014901375c 558 SUPERFAMILY SSF55073 132 291 1.02E-49 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_02045 87a7d0a432a9130bb283f99cf7579a48 183 SUPERFAMILY SSF48317 2 112 6.41E-20 T 13-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily THITH_02045 87a7d0a432a9130bb283f99cf7579a48 183 Pfam PF01569 PAP2 superfamily 2 109 3.3E-18 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THITH_02045 87a7d0a432a9130bb283f99cf7579a48 183 SMART SM00014 1 104 0.0073 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THITH_02045 87a7d0a432a9130bb283f99cf7579a48 183 Gene3D G3DSA:1.20.144.10 28 117 1.3E-14 T 13-10-2018 THITH_11015 8e22705b21597db5b1747fb2bfcbcf2c 306 Pfam PF00892 EamA-like transporter family 150 277 2.3E-13 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 THITH_11015 8e22705b21597db5b1747fb2bfcbcf2c 306 Pfam PF00892 EamA-like transporter family 2 132 2.3E-14 T 13-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 THITH_11015 8e22705b21597db5b1747fb2bfcbcf2c 306 SUPERFAMILY SSF103481 178 280 2.62E-13 T 13-10-2018 THITH_11015 8e22705b21597db5b1747fb2bfcbcf2c 306 SUPERFAMILY SSF103481 34 132 2.48E-12 T 13-10-2018 THITH_06860 ba44ee3955a61eb19fcb3868cbf7d88f 383 SUPERFAMILY SSF52821 16 134 2.62E-16 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_06860 ba44ee3955a61eb19fcb3868cbf7d88f 383 Gene3D G3DSA:3.40.250.10 7 135 2.4E-30 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_06860 ba44ee3955a61eb19fcb3868cbf7d88f 383 Hamap MF_01622 tRNA 2-selenouridine synthase [selU]. 3 369 45.706 T 13-10-2018 IPR017582 tRNA 2-selenouridine/geranyl-2-thiouridine synthase GO:0016785|GO:0043828|GO:0070329 THITH_06860 ba44ee3955a61eb19fcb3868cbf7d88f 383 SMART SM00450 5 134 2.5E-8 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_06860 ba44ee3955a61eb19fcb3868cbf7d88f 383 TIGRFAM TIGR03167 tRNA_sel_U_synt: tRNA 2-selenouridine synthase 19 350 9.7E-97 T 13-10-2018 IPR017582 tRNA 2-selenouridine/geranyl-2-thiouridine synthase GO:0016785|GO:0043828|GO:0070329 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 738 799 1.2E-31 T 13-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 Pfam PF00204 DNA gyrase B 228 397 2.8E-58 T 13-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 Gene3D G3DSA:3.40.50.670 709 809 7.9E-27 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 SMART SM00387 39 183 4.7E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 SUPERFAMILY SSF56719 401 800 7.06E-87 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 13 810 0.0 T 13-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 40 180 8.7E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 Gene3D G3DSA:3.40.50.670 405 576 2.3E-73 T 13-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 Gene3D G3DSA:3.30.230.10 228 399 2.4E-71 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 Pfam PF01751 Toprim domain 426 538 1.9E-16 T 13-10-2018 IPR006171 TOPRIM domain THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 SMART SM00433 43 803 1.7E-265 T 13-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 SUPERFAMILY SSF55874 13 225 8.91E-73 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR00418 DNA topoisomerase II family signature 427 441 1.2E-70 T 13-10-2018 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR00418 DNA topoisomerase II family signature 742 758 1.2E-70 T 13-10-2018 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR00418 DNA topoisomerase II family signature 43 58 1.2E-70 T 13-10-2018 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR00418 DNA topoisomerase II family signature 121 135 1.2E-70 T 13-10-2018 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR00418 DNA topoisomerase II family signature 275 288 1.2E-70 T 13-10-2018 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR00418 DNA topoisomerase II family signature 532 544 1.2E-70 T 13-10-2018 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR00418 DNA topoisomerase II family signature 512 529 1.2E-70 T 13-10-2018 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR00418 DNA topoisomerase II family signature 494 510 1.2E-70 T 13-10-2018 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR00418 DNA topoisomerase II family signature 78 91 1.2E-70 T 13-10-2018 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR01159 DNA gyrase subunit B signature 477 486 2.0E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR01159 DNA gyrase subunit B signature 779 795 2.0E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR01159 DNA gyrase subunit B signature 227 249 2.0E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR01159 DNA gyrase subunit B signature 319 335 2.0E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR01159 DNA gyrase subunit B signature 763 775 2.0E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR01159 DNA gyrase subunit B signature 13 23 2.0E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR01159 DNA gyrase subunit B signature 381 401 2.0E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR01159 DNA gyrase subunit B signature 367 381 2.0E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR01159 DNA gyrase subunit B signature 188 203 2.0E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 PRINTS PR01159 DNA gyrase subunit B signature 203 216 2.0E-77 T 13-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 ProSitePatterns PS00177 DNA topoisomerase II signature. 429 437 - T 13-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 Gene3D G3DSA:3.30.565.10 9 227 3.5E-93 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 10 810 101.478 T 13-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_00020 5827af70f2177c98bed90f7ab1daf591 810 SUPERFAMILY SSF54211 228 398 4.93E-59 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_12640 c6ad9e4bd62b63f82fbe85cc5447bdfd 341 SUPERFAMILY SSF52833 195 290 4.49E-5 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_12640 c6ad9e4bd62b63f82fbe85cc5447bdfd 341 Pfam PF13899 Thioredoxin-like 196 246 1.9E-6 T 13-10-2018 THITH_12640 c6ad9e4bd62b63f82fbe85cc5447bdfd 341 SUPERFAMILY SSF52833 29 143 8.61E-13 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_12640 c6ad9e4bd62b63f82fbe85cc5447bdfd 341 Pfam PF13098 Thioredoxin-like domain 43 141 6.5E-10 T 13-10-2018 IPR012336 Thioredoxin-like fold THITH_12640 c6ad9e4bd62b63f82fbe85cc5447bdfd 341 Gene3D G3DSA:3.40.30.10 192 340 2.8E-7 T 13-10-2018 THITH_12640 c6ad9e4bd62b63f82fbe85cc5447bdfd 341 Gene3D G3DSA:3.40.30.10 26 170 5.0E-21 T 13-10-2018 THITH_00740 f023a832b69fa796a250621073a1f0c7 1220 Pfam PF00580 UvrD/REP helicase N-terminal domain 10 439 8.8E-57 T 13-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 THITH_00740 f023a832b69fa796a250621073a1f0c7 1220 Hamap MF_01485 RecBCD enzyme subunit RecB [recB]. 2 1209 21.495 T 13-10-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 THITH_00740 f023a832b69fa796a250621073a1f0c7 1220 Pfam PF13361 UvrD-like helicase C-terminal domain 699 831 8.0E-11 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 THITH_00740 f023a832b69fa796a250621073a1f0c7 1220 Pfam PF12705 PD-(D/E)XK nuclease superfamily 980 1183 1.9E-5 T 13-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type THITH_00740 f023a832b69fa796a250621073a1f0c7 1220 Gene3D G3DSA:1.10.3170.10 156 351 1.7E-136 T 13-10-2018 THITH_00740 f023a832b69fa796a250621073a1f0c7 1220 SUPERFAMILY SSF52540 13 834 3.19E-108 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00740 f023a832b69fa796a250621073a1f0c7 1220 Gene3D G3DSA:1.10.486.10 598 743 2.3E-151 T 13-10-2018 THITH_00740 f023a832b69fa796a250621073a1f0c7 1220 TIGRFAM TIGR00609 recB: exodeoxyribonuclease V, beta subunit 6 1207 0.0 T 13-10-2018 IPR004586 RecBCD enzyme subunit RecB GO:0005524|GO:0006281|GO:0008854 THITH_00740 f023a832b69fa796a250621073a1f0c7 1220 SUPERFAMILY SSF52980 915 1208 6.43E-65 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_00740 f023a832b69fa796a250621073a1f0c7 1220 Gene3D G3DSA:3.40.50.300 5 441 1.7E-136 T 13-10-2018 THITH_00740 f023a832b69fa796a250621073a1f0c7 1220 Gene3D G3DSA:3.40.50.300 451 860 2.3E-151 T 13-10-2018 THITH_00740 f023a832b69fa796a250621073a1f0c7 1220 Gene3D G3DSA:3.90.320.10 905 1212 8.9E-81 T 13-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal THITH_16730 ba48714e9e6fdcebdb57192fccefbbde 246 Pfam PF12800 4Fe-4S binding domain 9 23 0.05 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_16730 ba48714e9e6fdcebdb57192fccefbbde 246 Pfam PF13247 4Fe-4S dicluster domain 49 111 3.0E-15 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_16730 ba48714e9e6fdcebdb57192fccefbbde 246 Pfam PF13247 4Fe-4S dicluster domain 158 192 3.5E-8 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_16730 ba48714e9e6fdcebdb57192fccefbbde 246 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 90 101 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_16730 ba48714e9e6fdcebdb57192fccefbbde 246 SUPERFAMILY SSF54862 2 226 4.19E-67 T 13-10-2018 THITH_08620 3d5cd13201732e69f38df321b20e680d 344 SUPERFAMILY SSF51445 6 297 2.53E-73 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily THITH_08620 3d5cd13201732e69f38df321b20e680d 344 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 20 297 1.2E-64 T 13-10-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 THITH_08620 3d5cd13201732e69f38df321b20e680d 344 Gene3D G3DSA:3.20.20.300 5 341 9.7E-102 T 13-10-2018 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily GO:0004553|GO:0005975 THITH_08620 3d5cd13201732e69f38df321b20e680d 344 Hamap MF_00364 Beta-hexosaminidase [nagZ]. 7 337 48.324 T 13-10-2018 IPR022956 Beta-hexosaminidase, bacterial GO:0004563 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|MetaCyc: PWY-7883 THITH_01430 2355d7276e9d32a33261a50e019027e3 443 SUPERFAMILY SSF52540 83 368 3.91E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01430 2355d7276e9d32a33261a50e019027e3 443 Gene3D G3DSA:3.40.50.300 230 396 1.5E-46 T 13-10-2018 THITH_01430 2355d7276e9d32a33261a50e019027e3 443 SMART SM00490 270 351 1.2E-30 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_01430 2355d7276e9d32a33261a50e019027e3 443 Pfam PF00270 DEAD/DEAH box helicase 33 204 2.2E-43 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THITH_01430 2355d7276e9d32a33261a50e019027e3 443 SMART SM00487 28 234 5.3E-52 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_01430 2355d7276e9d32a33261a50e019027e3 443 Gene3D G3DSA:3.40.50.300 2 222 2.3E-70 T 13-10-2018 THITH_01430 2355d7276e9d32a33261a50e019027e3 443 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 163 171 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site THITH_01430 2355d7276e9d32a33261a50e019027e3 443 Pfam PF00271 Helicase conserved C-terminal domain 247 351 2.3E-28 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_01430 2355d7276e9d32a33261a50e019027e3 443 Hamap MF_00661 ATP-dependent RNA helicase RhlB [rhlB]. 8 389 51.393 T 13-10-2018 IPR023554 ATP-dependent RNA helicase RhlB type GO:0004004 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 Gene3D G3DSA:2.40.50.140 139 202 2.7E-18 T 13-10-2018 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 SUPERFAMILY SSF54814 204 282 5.43E-30 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 Gene3D G3DSA:1.10.150.20 435 493 3.3E-20 T 13-10-2018 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 414 29.879 T 13-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 Pfam PF14520 Helix-hairpin-helix domain 437 490 4.5E-7 T 13-10-2018 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 Gene3D G3DSA:1.10.150.20 357 425 3.0E-25 T 13-10-2018 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 SUPERFAMILY SSF54814 283 345 7.19E-16 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 Pfam PF00575 S1 RNA binding domain 137 183 1.5E-5 T 13-10-2018 IPR003029 S1 domain GO:0003676 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 SMART SM00322 305 378 0.032 T 13-10-2018 IPR004087 K Homology domain GO:0003676 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 SMART SM00322 234 297 17.0 T 13-10-2018 IPR004087 K Homology domain GO:0003676 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 SUPERFAMILY SSF50249 136 203 1.56E-16 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 SUPERFAMILY SSF47794 359 420 1.37E-15 T 13-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 Gene3D G3DSA:3.30.300.20 203 281 6.4E-31 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 SUPERFAMILY SSF47794 434 494 5.02E-14 T 13-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 Gene3D G3DSA:3.30.300.20 282 351 9.2E-27 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 TIGRFAM TIGR01954 nusA_Cterm_rpt: transcription termination factor NusA, C-terminal duplication 369 418 1.6E-16 T 13-10-2018 IPR010214 Transcription termination factor NusA, C-terminal duplication THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 SMART SM00316 137 204 5.4E-9 T 13-10-2018 IPR022967 RNA-binding domain, S1 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 Pfam PF08529 NusA N-terminal domain 4 127 1.1E-38 T 13-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 Gene3D G3DSA:3.30.1480.10 1 132 2.5E-44 T 13-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 SUPERFAMILY SSF69705 1 129 4.84E-40 T 13-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 5 347 1.2E-124 T 13-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 THITH_12910 b756336adc1db4b8d6fc2ccddc2b1450 498 Pfam PF13184 NusA-like KH domain 234 301 8.4E-29 T 13-10-2018 IPR025249 KH domain, NusA-like GO:0003723 THITH_16355 fe2859c178b39631c762881ed425e3a4 67 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 67 29.953 T 13-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_16355 fe2859c178b39631c762881ed425e3a4 67 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_16355 fe2859c178b39631c762881ed425e3a4 67 SUPERFAMILY SSF143800 1 66 2.2E-28 T 13-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_16355 fe2859c178b39631c762881ed425e3a4 67 PRINTS PR01249 Ribosomal protein L31 signature 47 65 6.5E-23 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_16355 fe2859c178b39631c762881ed425e3a4 67 PRINTS PR01249 Ribosomal protein L31 signature 2 19 6.5E-23 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_16355 fe2859c178b39631c762881ed425e3a4 67 PRINTS PR01249 Ribosomal protein L31 signature 32 47 6.5E-23 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_16355 fe2859c178b39631c762881ed425e3a4 67 Gene3D G3DSA:2.30.170.50 1 67 2.7E-34 T 13-10-2018 THITH_16355 fe2859c178b39631c762881ed425e3a4 67 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 66 2.6E-35 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_16355 fe2859c178b39631c762881ed425e3a4 67 Pfam PF01197 Ribosomal protein L31 1 66 3.4E-35 T 13-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14205 eadae5913adfae67e80ef3c74d2a91f9 168 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 13 165 4.0E-64 T 13-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 THITH_14205 eadae5913adfae67e80ef3c74d2a91f9 168 Pfam PF03719 Ribosomal protein S5, C-terminal domain 89 159 2.6E-28 T 13-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 THITH_14205 eadae5913adfae67e80ef3c74d2a91f9 168 SUPERFAMILY SSF54768 10 78 1.05E-22 T 13-10-2018 THITH_14205 eadae5913adfae67e80ef3c74d2a91f9 168 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 165 33.481 T 13-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 THITH_14205 eadae5913adfae67e80ef3c74d2a91f9 168 Gene3D G3DSA:3.30.230.10 76 168 6.5E-35 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THITH_14205 eadae5913adfae67e80ef3c74d2a91f9 168 Pfam PF00333 Ribosomal protein S5, N-terminal domain 14 76 1.9E-27 T 13-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 THITH_14205 eadae5913adfae67e80ef3c74d2a91f9 168 SUPERFAMILY SSF54211 81 161 5.06E-25 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_14205 eadae5913adfae67e80ef3c74d2a91f9 168 ProSitePatterns PS00585 Ribosomal protein S5 signature. 30 62 - T 13-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site THITH_14205 eadae5913adfae67e80ef3c74d2a91f9 168 Gene3D G3DSA:3.30.160.20 3 74 3.2E-29 T 13-10-2018 THITH_12145 fc321480167f9d45f4ec90ab6885e1a7 257 ProSitePatterns PS00501 Signal peptidases I serine active site. 70 77 - T 13-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 THITH_12145 fc321480167f9d45f4ec90ab6885e1a7 257 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 200 219 2.2E-24 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 THITH_12145 fc321480167f9d45f4ec90ab6885e1a7 257 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 61 77 2.2E-24 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 THITH_12145 fc321480167f9d45f4ec90ab6885e1a7 257 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 125 137 2.2E-24 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 THITH_12145 fc321480167f9d45f4ec90ab6885e1a7 257 ProSitePatterns PS00760 Signal peptidases I lysine active site. 127 139 - T 13-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 THITH_12145 fc321480167f9d45f4ec90ab6885e1a7 257 ProSitePatterns PS00761 Signal peptidases I signature 3. 205 218 - T 13-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 THITH_12145 fc321480167f9d45f4ec90ab6885e1a7 257 Pfam PF00717 Peptidase S24-like 67 149 1.2E-21 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C THITH_12145 fc321480167f9d45f4ec90ab6885e1a7 257 Gene3D G3DSA:2.10.109.10 59 240 4.9E-66 T 13-10-2018 THITH_12145 fc321480167f9d45f4ec90ab6885e1a7 257 SUPERFAMILY SSF51306 59 253 6.8E-67 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily THITH_12145 fc321480167f9d45f4ec90ab6885e1a7 257 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 47 239 2.5E-50 T 13-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 THITH_12145 fc321480167f9d45f4ec90ab6885e1a7 257 Gene3D G3DSA:2.170.230.10 136 199 4.9E-66 T 13-10-2018 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 PRINTS PR00702 Acriflavin resistance protein family signature 13 37 2.3E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 PRINTS PR00702 Acriflavin resistance protein family signature 403 427 2.3E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 PRINTS PR00702 Acriflavin resistance protein family signature 349 372 2.3E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 PRINTS PR00702 Acriflavin resistance protein family signature 482 505 2.3E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 PRINTS PR00702 Acriflavin resistance protein family signature 41 59 2.3E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 PRINTS PR00702 Acriflavin resistance protein family signature 457 480 2.3E-24 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 Gene3D G3DSA:1.20.1640.10 533 1073 3.4E-231 T 13-10-2018 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 Gene3D G3DSA:3.30.2090.10 752 842 3.4E-231 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 Gene3D G3DSA:3.30.70.1320 139 343 3.4E-231 T 13-10-2018 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 SUPERFAMILY SSF82866 308 508 9.02E-39 T 13-10-2018 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 Gene3D G3DSA:3.30.70.1430 43 850 3.4E-231 T 13-10-2018 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 Gene3D G3DSA:1.20.1640.10 19 532 3.4E-231 T 13-10-2018 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 SUPERFAMILY SSF82714 754 838 3.01E-12 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 Gene3D G3DSA:3.30.70.1430 593 703 3.4E-231 T 13-10-2018 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 SUPERFAMILY SSF82693 589 704 2.2E-14 T 13-10-2018 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 Gene3D G3DSA:3.30.2090.10 185 276 3.4E-231 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 SUPERFAMILY SSF82866 844 1078 1.31E-40 T 13-10-2018 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 SUPERFAMILY SSF82693 145 340 2.09E-10 T 13-10-2018 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 SUPERFAMILY SSF82714 190 271 1.28E-15 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 Gene3D G3DSA:3.30.70.1440 704 918 3.4E-231 T 13-10-2018 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 SUPERFAMILY SSF82693 43 138 2.62E-18 T 13-10-2018 THITH_02835 f75508d0251bb4ea34d7f72ee59d3a59 1088 Pfam PF00873 AcrB/AcrD/AcrF family 16 1074 3.6E-151 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_15795 ded6cc58572ab5dbff4b5577a7d66c36 1116 Pfam PF09989 CoA enzyme activase uncharacterised domain (DUF2229) 755 986 9.1E-48 T 13-10-2018 IPR018709 CoA enzyme activase, domain of unknown function DUF2229 THITH_15795 ded6cc58572ab5dbff4b5577a7d66c36 1116 SUPERFAMILY SSF53067 351 617 2.25E-33 T 13-10-2018 THITH_15795 ded6cc58572ab5dbff4b5577a7d66c36 1116 Gene3D G3DSA:3.30.420.40 352 618 1.6E-64 T 13-10-2018 THITH_15795 ded6cc58572ab5dbff4b5577a7d66c36 1116 Gene3D G3DSA:3.30.420.40 3 277 4.8E-50 T 13-10-2018 THITH_15795 ded6cc58572ab5dbff4b5577a7d66c36 1116 SUPERFAMILY SSF53067 2 276 7.5E-24 T 13-10-2018 THITH_15795 ded6cc58572ab5dbff4b5577a7d66c36 1116 Gene3D G3DSA:3.30.420.40 449 601 1.6E-64 T 13-10-2018 THITH_15795 ded6cc58572ab5dbff4b5577a7d66c36 1116 Gene3D G3DSA:3.30.420.40 98 263 4.8E-50 T 13-10-2018 THITH_15795 ded6cc58572ab5dbff4b5577a7d66c36 1116 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 352 618 1.9E-45 T 13-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 THITH_15795 ded6cc58572ab5dbff4b5577a7d66c36 1116 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 3 222 8.9E-22 T 13-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 THITH_11425 b2101c85b7260585c1d1935273aa11a6 443 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 346 358 - T 13-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site THITH_11425 b2101c85b7260585c1d1935273aa11a6 443 SUPERFAMILY SSF55920 176 430 7.98E-85 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like THITH_11425 b2101c85b7260585c1d1935273aa11a6 443 Gene3D G3DSA:3.40.350.10 1 170 4.3E-54 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal THITH_11425 b2101c85b7260585c1d1935273aa11a6 443 SMART SM01011 1 135 7.4E-62 T 13-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 THITH_11425 b2101c85b7260585c1d1935273aa11a6 443 Gene3D G3DSA:3.90.230.10 171 438 7.7E-101 T 13-10-2018 THITH_11425 b2101c85b7260585c1d1935273aa11a6 443 Pfam PF00557 Metallopeptidase family M24 180 409 3.2E-64 T 13-10-2018 IPR000994 Peptidase M24 THITH_11425 b2101c85b7260585c1d1935273aa11a6 443 PRINTS PR00599 Methionine aminopeptidase-1 signature 369 381 2.8E-5 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 THITH_11425 b2101c85b7260585c1d1935273aa11a6 443 PRINTS PR00599 Methionine aminopeptidase-1 signature 251 267 2.8E-5 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 THITH_11425 b2101c85b7260585c1d1935273aa11a6 443 Pfam PF05195 Aminopeptidase P, N-terminal domain 6 121 1.7E-37 T 13-10-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 THITH_11425 b2101c85b7260585c1d1935273aa11a6 443 SUPERFAMILY SSF53092 2 173 7.59E-51 T 13-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal THITH_14800 98da06bb1bd1cb3be2a71c7d45522d26 535 Gene3D G3DSA:1.25.40.10 350 532 2.8E-32 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_14800 98da06bb1bd1cb3be2a71c7d45522d26 535 SUPERFAMILY SSF48452 20 115 1.14E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_14800 98da06bb1bd1cb3be2a71c7d45522d26 535 SUPERFAMILY SSF48452 116 314 1.39E-20 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_14800 98da06bb1bd1cb3be2a71c7d45522d26 535 Pfam PF14559 Tetratricopeptide repeat 468 530 3.6E-6 T 13-10-2018 THITH_14800 98da06bb1bd1cb3be2a71c7d45522d26 535 Gene3D G3DSA:1.25.40.10 6 117 6.1E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_14800 98da06bb1bd1cb3be2a71c7d45522d26 535 SMART SM00028 422 456 120.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_14800 98da06bb1bd1cb3be2a71c7d45522d26 535 SMART SM00028 13 48 460.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_14800 98da06bb1bd1cb3be2a71c7d45522d26 535 SMART SM00028 183 216 17.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_14800 98da06bb1bd1cb3be2a71c7d45522d26 535 SMART SM00028 490 523 0.16 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_14800 98da06bb1bd1cb3be2a71c7d45522d26 535 SMART SM00028 285 318 94.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_14800 98da06bb1bd1cb3be2a71c7d45522d26 535 SMART SM00028 388 421 0.001 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_14800 98da06bb1bd1cb3be2a71c7d45522d26 535 Pfam PF13432 Tetratricopeptide repeat 359 422 3.5E-9 T 13-10-2018 THITH_14800 98da06bb1bd1cb3be2a71c7d45522d26 535 Pfam PF13432 Tetratricopeptide repeat 154 215 5.3E-6 T 13-10-2018 THITH_14800 98da06bb1bd1cb3be2a71c7d45522d26 535 Pfam PF13432 Tetratricopeptide repeat 257 311 2.9E-7 T 13-10-2018 THITH_14800 98da06bb1bd1cb3be2a71c7d45522d26 535 SUPERFAMILY SSF48452 356 524 2.28E-29 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_14800 98da06bb1bd1cb3be2a71c7d45522d26 535 Gene3D G3DSA:1.25.40.10 118 321 2.6E-28 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_15315 4f6877845a8a4281dd3ab01837ee5e49 147 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 17 134 9.0E-41 T 13-10-2018 THITH_15315 4f6877845a8a4281dd3ab01837ee5e49 147 SUPERFAMILY SSF52304 3 145 1.16E-59 T 13-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THITH_15315 4f6877845a8a4281dd3ab01837ee5e49 147 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 13-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THITH_15315 4f6877845a8a4281dd3ab01837ee5e49 147 Pfam PF01220 Dehydroquinase class II 4 140 1.4E-59 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THITH_15315 4f6877845a8a4281dd3ab01837ee5e49 147 Gene3D G3DSA:3.40.50.9100 1 146 8.6E-64 T 13-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THITH_15315 4f6877845a8a4281dd3ab01837ee5e49 147 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 142 9.4E-59 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THITH_15315 4f6877845a8a4281dd3ab01837ee5e49 147 PIRSF PIRSF001399 1 146 9.5E-58 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THITH_15315 4f6877845a8a4281dd3ab01837ee5e49 147 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 147 69.202 T 13-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 THITH_11060 adba49d3dd042e5bd29836964d478643 393 SUPERFAMILY SSF116734 196 392 1.64E-28 T 13-10-2018 THITH_11060 adba49d3dd042e5bd29836964d478643 393 Gene3D G3DSA:3.90.220.20 173 371 5.4E-81 T 13-10-2018 THITH_11060 adba49d3dd042e5bd29836964d478643 393 Gene3D G3DSA:3.90.220.20 3 389 5.4E-81 T 13-10-2018 THITH_11060 adba49d3dd042e5bd29836964d478643 393 Pfam PF01420 Type I restriction modification DNA specificity domain 201 368 6.2E-14 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THITH_11060 adba49d3dd042e5bd29836964d478643 393 Pfam PF01420 Type I restriction modification DNA specificity domain 58 177 4.5E-10 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THITH_11060 adba49d3dd042e5bd29836964d478643 393 SUPERFAMILY SSF116734 3 197 7.85E-25 T 13-10-2018 THITH_01190 ca4b098c2876913b87bb924dc050bb1b 235 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 48 234 9.7E-52 T 13-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 THITH_01190 ca4b098c2876913b87bb924dc050bb1b 235 Gene3D G3DSA:3.40.50.150 26 234 3.2E-68 T 13-10-2018 THITH_01190 ca4b098c2876913b87bb924dc050bb1b 235 SUPERFAMILY SSF53335 14 234 6.75E-34 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_01190 ca4b098c2876913b87bb924dc050bb1b 235 Pfam PF02390 Putative methyltransferase 60 228 1.2E-52 T 13-10-2018 THITH_01190 ca4b098c2876913b87bb924dc050bb1b 235 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 20 234 31.939 T 13-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 THITH_12890 74d2d649d0d57c31719ac5a5c2fd5d11 89 SMART SM01387 8 88 3.2E-49 T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_12890 74d2d649d0d57c31719ac5a5c2fd5d11 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 21.744 T 13-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_12890 74d2d649d0d57c31719ac5a5c2fd5d11 89 Pfam PF00312 Ribosomal protein S15 9 88 8.1E-36 T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_12890 74d2d649d0d57c31719ac5a5c2fd5d11 89 Gene3D G3DSA:1.10.287.10 2 89 2.7E-35 T 13-10-2018 THITH_12890 74d2d649d0d57c31719ac5a5c2fd5d11 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 5 89 8.0E-38 T 13-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_12890 74d2d649d0d57c31719ac5a5c2fd5d11 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 4.0E-28 T 13-10-2018 THITH_12890 74d2d649d0d57c31719ac5a5c2fd5d11 89 SUPERFAMILY SSF47060 4 89 6.77E-35 T 13-10-2018 IPR009068 S15/NS1, RNA-binding THITH_12890 74d2d649d0d57c31719ac5a5c2fd5d11 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 13-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_12170 0c7bb4b933919ca5f0c7e699030953d6 329 Pfam PF17188 MucB/RseB C-terminal domain 222 316 1.4E-23 T 13-10-2018 IPR033436 MucB/RseB, C-terminal THITH_12170 0c7bb4b933919ca5f0c7e699030953d6 329 Pfam PF03888 MucB/RseB N-terminal domain 27 199 1.2E-45 T 13-10-2018 IPR033434 MucB/RseB, N-terminal THITH_12170 0c7bb4b933919ca5f0c7e699030953d6 329 Gene3D G3DSA:2.50.20.10 25 200 8.0E-43 T 13-10-2018 THITH_12170 0c7bb4b933919ca5f0c7e699030953d6 329 PIRSF PIRSF005427 3 324 3.1E-76 T 13-10-2018 IPR005588 MucB/RseB THITH_12170 0c7bb4b933919ca5f0c7e699030953d6 329 Gene3D G3DSA:3.30.200.100 222 321 8.1E-19 T 13-10-2018 IPR038484 MucB/RseB, C-terminal domain superfamily THITH_12895 a5253694aba885c5f09192714ceff75c 308 SUPERFAMILY SSF88697 243 301 2.16E-11 T 13-10-2018 IPR015947 PUA-like superfamily THITH_12895 a5253694aba885c5f09192714ceff75c 308 Gene3D G3DSA:2.30.130.10 242 303 1.8E-20 T 13-10-2018 IPR036974 PUA domain superfamily GO:0003723 THITH_12895 a5253694aba885c5f09192714ceff75c 308 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 8 300 18.944 T 13-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_12895 a5253694aba885c5f09192714ceff75c 308 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 8 217 4.2E-75 T 13-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_12895 a5253694aba885c5f09192714ceff75c 308 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 179 240 1.2E-19 T 13-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 THITH_12895 a5253694aba885c5f09192714ceff75c 308 Pfam PF09157 Pseudouridine synthase II TruB, C-terminal 244 300 1.4E-17 T 13-10-2018 IPR015240 tRNA pseudouridine synthase II, TruB, subfamily 1, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_12895 a5253694aba885c5f09192714ceff75c 308 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 31 178 1.3E-55 T 13-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 THITH_12895 a5253694aba885c5f09192714ceff75c 308 SUPERFAMILY SSF55120 7 222 9.11E-79 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_12895 a5253694aba885c5f09192714ceff75c 308 Gene3D G3DSA:3.30.2350.10 2 240 3.9E-87 T 13-10-2018 THITH_11590 41d790d2d8c2f8b9aa10417b84e94288 58 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 38 6.6E-7 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 THITH_11590 41d790d2d8c2f8b9aa10417b84e94288 58 Gene3D G3DSA:3.40.50.970 1 49 4.7E-7 T 13-10-2018 THITH_11590 41d790d2d8c2f8b9aa10417b84e94288 58 SUPERFAMILY SSF52518 1 40 6.96E-6 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold THITH_04505 3646d0d07a00fd0c34c2f2d2d88b2a99 470 Pfam PF01235 Sodium:alanine symporter family 61 453 5.8E-131 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THITH_04505 3646d0d07a00fd0c34c2f2d2d88b2a99 470 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 96 111 - T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THITH_04505 3646d0d07a00fd0c34c2f2d2d88b2a99 470 PRINTS PR00175 Sodium/alanine symporter signature 96 118 4.8E-53 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THITH_04505 3646d0d07a00fd0c34c2f2d2d88b2a99 470 PRINTS PR00175 Sodium/alanine symporter signature 311 329 4.8E-53 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THITH_04505 3646d0d07a00fd0c34c2f2d2d88b2a99 470 PRINTS PR00175 Sodium/alanine symporter signature 189 207 4.8E-53 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THITH_04505 3646d0d07a00fd0c34c2f2d2d88b2a99 470 PRINTS PR00175 Sodium/alanine symporter signature 217 236 4.8E-53 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THITH_04505 3646d0d07a00fd0c34c2f2d2d88b2a99 470 PRINTS PR00175 Sodium/alanine symporter signature 414 434 4.8E-53 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THITH_04505 3646d0d07a00fd0c34c2f2d2d88b2a99 470 PRINTS PR00175 Sodium/alanine symporter signature 355 377 4.8E-53 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THITH_04505 3646d0d07a00fd0c34c2f2d2d88b2a99 470 TIGRFAM TIGR00835 agcS: amino acid carrier protein 17 443 1.4E-137 T 13-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 THITH_14015 9fd00d0b6ad4d59e6e862e100924663b 560 SUPERFAMILY SSF55785 200 258 7.18E-6 T 13-10-2018 IPR035965 PAS domain superfamily THITH_14015 9fd00d0b6ad4d59e6e862e100924663b 560 Gene3D G3DSA:3.30.450.20 198 311 1.8E-8 T 13-10-2018 THITH_14015 9fd00d0b6ad4d59e6e862e100924663b 560 Gene3D G3DSA:1.10.287.130 313 388 6.0E-18 T 13-10-2018 THITH_14015 9fd00d0b6ad4d59e6e862e100924663b 560 SUPERFAMILY SSF47384 318 386 1.96E-13 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_14015 9fd00d0b6ad4d59e6e862e100924663b 560 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 433 537 4.6E-12 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_14015 9fd00d0b6ad4d59e6e862e100924663b 560 Gene3D G3DSA:3.30.565.10 390 546 5.2E-25 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_14015 9fd00d0b6ad4d59e6e862e100924663b 560 SMART SM00388 324 390 6.1E-16 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_14015 9fd00d0b6ad4d59e6e862e100924663b 560 PRINTS PR00344 Bacterial sensor protein C-terminal signature 475 489 2.7E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_14015 9fd00d0b6ad4d59e6e862e100924663b 560 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 503 2.7E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_14015 9fd00d0b6ad4d59e6e862e100924663b 560 PRINTS PR00344 Bacterial sensor protein C-terminal signature 504 522 2.7E-7 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_14015 9fd00d0b6ad4d59e6e862e100924663b 560 Pfam PF00512 His Kinase A (phospho-acceptor) domain 324 387 1.7E-14 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_14015 9fd00d0b6ad4d59e6e862e100924663b 560 SMART SM00387 432 543 6.8E-22 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_14015 9fd00d0b6ad4d59e6e862e100924663b 560 SUPERFAMILY SSF55874 381 542 3.54E-25 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_15585 6f3fca09c5e5e4822e8c284d82967aa8 180 Pfam PF01327 Polypeptide deformylase 4 152 9.5E-50 T 13-10-2018 IPR023635 Peptide deformylase THITH_15585 6f3fca09c5e5e4822e8c284d82967aa8 180 PIRSF PIRSF004749 1 174 1.6E-54 T 13-10-2018 IPR023635 Peptide deformylase THITH_15585 6f3fca09c5e5e4822e8c284d82967aa8 180 SUPERFAMILY SSF56420 3 162 1.7E-63 T 13-10-2018 IPR036821 Peptide deformylase superfamily THITH_15585 6f3fca09c5e5e4822e8c284d82967aa8 180 Gene3D G3DSA:3.90.45.10 1 166 1.8E-63 T 13-10-2018 IPR036821 Peptide deformylase superfamily THITH_15585 6f3fca09c5e5e4822e8c284d82967aa8 180 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 4 160 1.0E-55 T 13-10-2018 IPR023635 Peptide deformylase THITH_15585 6f3fca09c5e5e4822e8c284d82967aa8 180 PRINTS PR01576 Peptide deformylase signature 33 62 7.4E-39 T 13-10-2018 IPR023635 Peptide deformylase THITH_15585 6f3fca09c5e5e4822e8c284d82967aa8 180 PRINTS PR01576 Peptide deformylase signature 101 119 7.4E-39 T 13-10-2018 IPR023635 Peptide deformylase THITH_15585 6f3fca09c5e5e4822e8c284d82967aa8 180 PRINTS PR01576 Peptide deformylase signature 89 100 7.4E-39 T 13-10-2018 IPR023635 Peptide deformylase THITH_15585 6f3fca09c5e5e4822e8c284d82967aa8 180 PRINTS PR01576 Peptide deformylase signature 120 149 7.4E-39 T 13-10-2018 IPR023635 Peptide deformylase THITH_15585 6f3fca09c5e5e4822e8c284d82967aa8 180 Hamap MF_00163 Peptide deformylase [def]. 2 162 31.969 T 13-10-2018 IPR023635 Peptide deformylase THITH_07290 f2384cf42b1b42059c3b19331a73131b 137 Gene3D G3DSA:3.90.1010.10 1 132 2.4E-36 T 13-10-2018 THITH_07290 f2384cf42b1b42059c3b19331a73131b 137 SUPERFAMILY SSF82649 2 133 5.75E-35 T 13-10-2018 THITH_07290 f2384cf42b1b42059c3b19331a73131b 137 Pfam PF02657 Fe-S metabolism associated domain 6 128 4.1E-34 T 13-10-2018 IPR003808 Fe-S metabolism associated domain, SufE-like THITH_14420 b2ff5a45e986260629be03f465626c35 930 Gene3D G3DSA:3.90.1440.10 254 388 1.8E-171 T 13-10-2018 THITH_14420 b2ff5a45e986260629be03f465626c35 930 SUPERFAMILY SSF52540 5 433 1.5E-76 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14420 b2ff5a45e986260629be03f465626c35 930 SUPERFAMILY SSF52540 437 639 7.6E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14420 b2ff5a45e986260629be03f465626c35 930 SMART SM00957 6 422 6.3E-297 T 13-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 THITH_14420 b2ff5a45e986260629be03f465626c35 930 Pfam PF01043 SecA preprotein cross-linking domain 257 378 2.1E-37 T 13-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 THITH_14420 b2ff5a45e986260629be03f465626c35 930 Gene3D G3DSA:3.40.50.300 437 641 1.9E-85 T 13-10-2018 THITH_14420 b2ff5a45e986260629be03f465626c35 930 Pfam PF07516 SecA Wing and Scaffold domain 638 851 1.7E-67 T 13-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 THITH_14420 b2ff5a45e986260629be03f465626c35 930 SMART SM00958 253 378 5.5E-78 T 13-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 THITH_14420 b2ff5a45e986260629be03f465626c35 930 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 186 839 2.4E-272 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THITH_14420 b2ff5a45e986260629be03f465626c35 930 PRINTS PR00906 SecA protein signature 117 127 3.8E-56 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THITH_14420 b2ff5a45e986260629be03f465626c35 930 PRINTS PR00906 SecA protein signature 359 381 3.8E-56 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THITH_14420 b2ff5a45e986260629be03f465626c35 930 PRINTS PR00906 SecA protein signature 433 446 3.8E-56 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THITH_14420 b2ff5a45e986260629be03f465626c35 930 PRINTS PR00906 SecA protein signature 101 115 3.8E-56 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THITH_14420 b2ff5a45e986260629be03f465626c35 930 PRINTS PR00906 SecA protein signature 63 87 3.8E-56 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THITH_14420 b2ff5a45e986260629be03f465626c35 930 PRINTS PR00906 SecA protein signature 396 413 3.8E-56 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THITH_14420 b2ff5a45e986260629be03f465626c35 930 Gene3D G3DSA:3.40.50.300 22 435 1.8E-171 T 13-10-2018 THITH_14420 b2ff5a45e986260629be03f465626c35 930 Pfam PF07517 SecA DEAD-like domain 7 422 1.8E-130 T 13-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 THITH_14420 b2ff5a45e986260629be03f465626c35 930 Gene3D G3DSA:1.10.3060.10 642 854 4.2E-79 T 13-10-2018 THITH_14420 b2ff5a45e986260629be03f465626c35 930 Gene3D G3DSA:3.10.450.50 881 929 4.8E-8 T 13-10-2018 THITH_14420 b2ff5a45e986260629be03f465626c35 930 ProSitePatterns PS01312 SecA family signature. 520 535 - T 13-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 THITH_14420 b2ff5a45e986260629be03f465626c35 930 SUPERFAMILY SSF81767 252 388 5.23E-43 T 13-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 THITH_14420 b2ff5a45e986260629be03f465626c35 930 SUPERFAMILY SSF81886 642 918 6.28E-82 T 13-10-2018 IPR036266 SecA, Wing/Scaffold superfamily THITH_14420 b2ff5a45e986260629be03f465626c35 930 Hamap MF_01382 Protein translocase subunit SecA [secA]. 5 853 20.083 T 13-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 THITH_14420 b2ff5a45e986260629be03f465626c35 930 Pfam PF02810 SEC-C motif 910 928 1.1E-10 T 13-10-2018 IPR004027 SEC-C motif THITH_02515 bc95e80d62466e259ea2161e9f1ee1f0 209 Gene3D G3DSA:3.20.20.70 10 209 2.3E-63 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_02515 bc95e80d62466e259ea2161e9f1ee1f0 209 Pfam PF02581 Thiamine monophosphate synthase 13 191 7.1E-55 T 13-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THITH_02515 bc95e80d62466e259ea2161e9f1ee1f0 209 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 11 209 27.103 T 13-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THITH_02515 bc95e80d62466e259ea2161e9f1ee1f0 209 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 13 203 1.4E-57 T 13-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THITH_02515 bc95e80d62466e259ea2161e9f1ee1f0 209 SUPERFAMILY SSF51391 9 206 3.01E-63 T 13-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THITH_10965 da35b5e1c220a94ca7de486a26336797 428 Pfam PF03349 Outer membrane protein transport protein (OMPP1/FadL/TodX) 13 406 5.1E-31 T 13-10-2018 IPR005017 Outer membrane protein transport protein (OMPP1/FadL/TodX) THITH_10965 da35b5e1c220a94ca7de486a26336797 428 SUPERFAMILY SSF56935 25 422 3.63E-50 T 13-10-2018 THITH_10965 da35b5e1c220a94ca7de486a26336797 428 Gene3D G3DSA:2.40.160.60 26 428 2.2E-85 T 13-10-2018 THITH_15710 485687c0277090fd01b3dc04b3acb2ed 176 Pfam PF07963 Prokaryotic N-terminal methylation motif 42 66 2.7E-8 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_15710 485687c0277090fd01b3dc04b3acb2ed 176 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 44 66 1.4E-6 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_15710 485687c0277090fd01b3dc04b3acb2ed 176 TIGRFAM TIGR02523 type_IV_pilV: type IV pilus modification protein PilV 45 98 2.4E-17 T 13-10-2018 IPR013362 Pilus modification type IV, PilV THITH_15710 485687c0277090fd01b3dc04b3acb2ed 176 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 45 65 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_13195 cc4277b69cb4c2c635c58d1223e11868 527 SUPERFAMILY SSF53955 118 276 5.77E-38 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily THITH_13195 cc4277b69cb4c2c635c58d1223e11868 527 Gene3D G3DSA:3.10.350.10 347 400 4.2E-16 T 13-10-2018 IPR036779 LysM domain superfamily THITH_13195 cc4277b69cb4c2c635c58d1223e11868 527 SUPERFAMILY SSF54106 349 393 6.41E-11 T 13-10-2018 THITH_13195 cc4277b69cb4c2c635c58d1223e11868 527 Gene3D G3DSA:3.10.350.10 462 524 8.4E-12 T 13-10-2018 IPR036779 LysM domain superfamily THITH_13195 cc4277b69cb4c2c635c58d1223e11868 527 SUPERFAMILY SSF54106 416 460 1.83E-10 T 13-10-2018 THITH_13195 cc4277b69cb4c2c635c58d1223e11868 527 Gene3D G3DSA:1.10.530.10 116 264 1.9E-28 T 13-10-2018 THITH_13195 cc4277b69cb4c2c635c58d1223e11868 527 Pfam PF01476 LysM domain 417 460 1.4E-13 T 13-10-2018 IPR018392 LysM domain THITH_13195 cc4277b69cb4c2c635c58d1223e11868 527 Pfam PF01476 LysM domain 476 516 9.4E-9 T 13-10-2018 IPR018392 LysM domain THITH_13195 cc4277b69cb4c2c635c58d1223e11868 527 Pfam PF01476 LysM domain 351 393 2.4E-11 T 13-10-2018 IPR018392 LysM domain THITH_13195 cc4277b69cb4c2c635c58d1223e11868 527 SMART SM00257 475 518 3.1E-8 T 13-10-2018 IPR018392 LysM domain THITH_13195 cc4277b69cb4c2c635c58d1223e11868 527 SMART SM00257 350 393 1.1E-13 T 13-10-2018 IPR018392 LysM domain THITH_13195 cc4277b69cb4c2c635c58d1223e11868 527 SMART SM00257 416 460 3.1E-13 T 13-10-2018 IPR018392 LysM domain THITH_13195 cc4277b69cb4c2c635c58d1223e11868 527 SUPERFAMILY SSF54106 474 518 3.4E-8 T 13-10-2018 THITH_13195 cc4277b69cb4c2c635c58d1223e11868 527 Pfam PF01464 Transglycosylase SLT domain 131 228 4.5E-23 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 THITH_13195 cc4277b69cb4c2c635c58d1223e11868 527 Gene3D G3DSA:3.10.350.10 413 461 2.7E-15 T 13-10-2018 IPR036779 LysM domain superfamily THITH_16090 9d980825fafe9c574f0ba2aa301548cc 276 Hamap MF_02095 3'(2'),5'-bisphosphate nucleotidase CysQ [cysQ]. 11 260 42.022 T 13-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 THITH_16090 9d980825fafe9c574f0ba2aa301548cc 276 SUPERFAMILY SSF56655 11 265 1.07E-77 T 13-10-2018 THITH_16090 9d980825fafe9c574f0ba2aa301548cc 276 Gene3D G3DSA:3.30.540.10 8 156 1.0E-43 T 13-10-2018 THITH_16090 9d980825fafe9c574f0ba2aa301548cc 276 Pfam PF00459 Inositol monophosphatase family 11 252 6.9E-50 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_16090 9d980825fafe9c574f0ba2aa301548cc 276 PRINTS PR00377 Inositol monophosphatase superfamily signature 215 239 8.7E-12 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_16090 9d980825fafe9c574f0ba2aa301548cc 276 PRINTS PR00377 Inositol monophosphatase superfamily signature 43 63 8.7E-12 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_16090 9d980825fafe9c574f0ba2aa301548cc 276 PRINTS PR00377 Inositol monophosphatase superfamily signature 65 81 8.7E-12 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_16090 9d980825fafe9c574f0ba2aa301548cc 276 PRINTS PR00377 Inositol monophosphatase superfamily signature 89 105 8.7E-12 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_16090 9d980825fafe9c574f0ba2aa301548cc 276 TIGRFAM TIGR01331 bisphos_cysQ: 3'(2'),5'-bisphosphate nucleotidase 12 257 2.1E-95 T 13-10-2018 IPR006240 3'(2'),5'-bisphosphate nucleotidase CysQ GO:0000287|GO:0006790|GO:0008441 KEGG: 00920+3.1.3.7 THITH_16090 9d980825fafe9c574f0ba2aa301548cc 276 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 89 102 - T 13-10-2018 IPR020583 Inositol monophosphatase, metal-binding site THITH_16090 9d980825fafe9c574f0ba2aa301548cc 276 Gene3D G3DSA:3.40.190.80 160 262 6.9E-36 T 13-10-2018 THITH_16090 9d980825fafe9c574f0ba2aa301548cc 276 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 218 232 - T 13-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 THITH_02325 031d77a37b58a94b3b76d1289d33914f 250 Gene3D G3DSA:3.40.50.300 1 250 7.0E-53 T 13-10-2018 THITH_02325 031d77a37b58a94b3b76d1289d33914f 250 PIRSF PIRSF009320 1 63 1.6E-9 T 13-10-2018 THITH_02325 031d77a37b58a94b3b76d1289d33914f 250 PIRSF PIRSF009320 89 250 9.4E-10 T 13-10-2018 THITH_02325 031d77a37b58a94b3b76d1289d33914f 250 SUPERFAMILY SSF52540 2 246 1.44E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_02325 031d77a37b58a94b3b76d1289d33914f 250 Pfam PF13614 AAA domain 2 164 2.3E-35 T 13-10-2018 IPR025669 AAA domain THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 Gene3D G3DSA:2.70.150.20 197 309 8.0E-41 T 13-10-2018 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 SUPERFAMILY SSF56784 423 724 9.51E-61 T 13-10-2018 IPR036412 HAD-like superfamily THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 Gene3D G3DSA:3.40.1110.10 436 556 1.6E-96 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 425 439 1.3E-28 T 13-10-2018 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 625 644 1.3E-28 T 13-10-2018 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 549 560 1.3E-28 T 13-10-2018 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 254 268 1.3E-28 T 13-10-2018 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 648 660 1.3E-28 T 13-10-2018 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 571 581 1.3E-28 T 13-10-2018 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 Pfam PF00122 E1-E2 ATPase 207 404 2.4E-53 T 13-10-2018 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 177 342 1.8E-20 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 370 708 2.4E-61 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 144 727 1.4E-190 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 427 433 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 Gene3D G3DSA:3.30.70.100 1 69 1.7E-8 T 13-10-2018 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 PRINTS PR00941 Cadmium-transporting ATPase signature 209 225 1.5E-6 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 PRINTS PR00941 Cadmium-transporting ATPase signature 289 303 1.5E-6 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 PRINTS PR00941 Cadmium-transporting ATPase signature 7 28 1.5E-6 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 PRINTS PR00941 Cadmium-transporting ATPase signature 189 209 1.5E-6 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 PRINTS PR00941 Cadmium-transporting ATPase signature 270 286 1.5E-6 T 13-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 SUPERFAMILY SSF81665 100 705 5.23E-13 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 SUPERFAMILY SSF55008 1 63 1.44E-9 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 Gene3D G3DSA:3.40.50.1000 406 677 1.6E-96 T 13-10-2018 IPR023214 HAD superfamily THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 SUPERFAMILY SSF81653 208 304 1.7E-26 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 THITH_08865 815b2d3726b50259ed0bb2c5fb545707 733 Pfam PF00702 haloacid dehalogenase-like hydrolase 421 639 8.5E-48 T 13-10-2018 THITH_01895 4c7fedfed1e92db1a676f35d442b3751 219 Gene3D G3DSA:3.90.220.20 11 164 5.1E-22 T 13-10-2018 THITH_01895 4c7fedfed1e92db1a676f35d442b3751 219 SUPERFAMILY SSF116734 29 168 5.89E-24 T 13-10-2018 THITH_03665 e14bdeb6d403d49a9e1edda69fbe8bc7 224 Gene3D G3DSA:1.25.40.10 23 224 1.4E-47 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_03665 e14bdeb6d403d49a9e1edda69fbe8bc7 224 Pfam PF08238 Sel1 repeat 126 160 1.8E-7 T 13-10-2018 IPR006597 Sel1-like repeat THITH_03665 e14bdeb6d403d49a9e1edda69fbe8bc7 224 Pfam PF08238 Sel1 repeat 55 89 4.8E-7 T 13-10-2018 IPR006597 Sel1-like repeat THITH_03665 e14bdeb6d403d49a9e1edda69fbe8bc7 224 Pfam PF08238 Sel1 repeat 162 192 1.4E-5 T 13-10-2018 IPR006597 Sel1-like repeat THITH_03665 e14bdeb6d403d49a9e1edda69fbe8bc7 224 Pfam PF08238 Sel1 repeat 90 125 1.3E-8 T 13-10-2018 IPR006597 Sel1-like repeat THITH_03665 e14bdeb6d403d49a9e1edda69fbe8bc7 224 SMART SM00671 54 89 2.7E-5 T 13-10-2018 IPR006597 Sel1-like repeat THITH_03665 e14bdeb6d403d49a9e1edda69fbe8bc7 224 SMART SM00671 90 125 5.4E-10 T 13-10-2018 IPR006597 Sel1-like repeat THITH_03665 e14bdeb6d403d49a9e1edda69fbe8bc7 224 SMART SM00671 126 161 1.5E-8 T 13-10-2018 IPR006597 Sel1-like repeat THITH_03665 e14bdeb6d403d49a9e1edda69fbe8bc7 224 SMART SM00671 162 197 2.4E-4 T 13-10-2018 IPR006597 Sel1-like repeat THITH_03665 e14bdeb6d403d49a9e1edda69fbe8bc7 224 SUPERFAMILY SSF81901 46 192 2.09E-37 T 13-10-2018 THITH_00590 e6f18a0473262a98cda3647770f88584 105 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 100 1.0E-20 T 13-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 THITH_00590 e6f18a0473262a98cda3647770f88584 105 Pfam PF03334 Na+/H+ antiporter subunit 11 89 8.7E-25 T 13-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 THITH_15685 52a6f1ac3060f1230cacf6e792247598 292 Pfam PF00696 Amino acid kinase family 26 269 4.6E-48 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 THITH_15685 52a6f1ac3060f1230cacf6e792247598 292 SUPERFAMILY SSF53633 5 291 9.29E-93 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THITH_15685 52a6f1ac3060f1230cacf6e792247598 292 Gene3D G3DSA:3.40.1160.10 2 292 2.5E-100 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THITH_15685 52a6f1ac3060f1230cacf6e792247598 292 PIRSF PIRSF000728 11 292 8.6E-107 T 13-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THITH_15685 52a6f1ac3060f1230cacf6e792247598 292 PRINTS PR00474 Glutamate 5-kinase family signature 192 219 3.5E-8 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THITH_15685 52a6f1ac3060f1230cacf6e792247598 292 PRINTS PR00474 Glutamate 5-kinase family signature 57 71 3.5E-8 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THITH_15685 52a6f1ac3060f1230cacf6e792247598 292 PRINTS PR00474 Glutamate 5-kinase family signature 242 262 3.5E-8 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THITH_15685 52a6f1ac3060f1230cacf6e792247598 292 TIGRFAM TIGR00761 argB: acetylglutamate kinase 27 267 4.9E-77 T 13-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THITH_15685 52a6f1ac3060f1230cacf6e792247598 292 Hamap MF_00082 Acetylglutamate kinase [argB]. 25 285 49.402 T 13-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THITH_09110 d3a751d633b4e4caf377f993f5c8f652 281 TIGRFAM TIGR03465 HpnD: squalene synthase HpnD 10 274 1.6E-116 T 13-10-2018 IPR017828 Squalene synthase HpnD-like GO:0016117|GO:0016767 THITH_09110 d3a751d633b4e4caf377f993f5c8f652 281 Pfam PF00494 Squalene/phytoene synthase 13 264 2.0E-81 T 13-10-2018 THITH_09110 d3a751d633b4e4caf377f993f5c8f652 281 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 122 137 - T 13-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 THITH_09110 d3a751d633b4e4caf377f993f5c8f652 281 Gene3D G3DSA:1.10.600.10 3 277 1.4E-88 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily THITH_09110 d3a751d633b4e4caf377f993f5c8f652 281 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 152 177 - T 13-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 THITH_09110 d3a751d633b4e4caf377f993f5c8f652 281 SUPERFAMILY SSF48576 3 277 2.73E-92 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily THITH_11600 160dcc4df19a3795810ff95a11d31439 353 Pfam PF11376 Protein of unknown function (DUF3179) 67 348 6.5E-88 T 13-10-2018 IPR021516 Protein of unknown function DUF3179 THITH_00095 645950e3a5e76761f7d09ef537b39f7f 163 SUPERFAMILY SSF103054 81 156 1.07E-12 T 13-10-2018 IPR023229 Type II secretion system protein M, periplasmic domain superfamily THITH_00095 645950e3a5e76761f7d09ef537b39f7f 163 Gene3D G3DSA:3.30.1360.100 83 159 4.6E-11 T 13-10-2018 THITH_00095 645950e3a5e76761f7d09ef537b39f7f 163 Pfam PF04612 Type II secretion system (T2SS), protein M 2 156 1.3E-32 T 13-10-2018 IPR007690 Type II secretion system, protein M GO:0009306 THITH_07210 8e170769be9b92a0d11f48071cb651b6 891 Gene3D G3DSA:3.40.50.300 271 519 2.6E-18 T 13-10-2018 THITH_07210 8e170769be9b92a0d11f48071cb651b6 891 Pfam PF13476 AAA domain 275 503 9.0E-13 T 13-10-2018 IPR038729 Rad50/SbcC-type AAA domain THITH_07210 8e170769be9b92a0d11f48071cb651b6 891 SUPERFAMILY SSF89550 46 157 2.75E-12 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 THITH_07210 8e170769be9b92a0d11f48071cb651b6 891 Gene3D G3DSA:3.20.20.140 39 236 1.9E-15 T 13-10-2018 THITH_07210 8e170769be9b92a0d11f48071cb651b6 891 SUPERFAMILY SSF52540 278 845 1.16E-27 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16635 4a68f97c39e4e21504ab2ee3e69f6351 425 Pfam PF06114 IrrE N-terminal-like domain 291 374 1.5E-6 T 13-10-2018 IPR010359 IrrE N-terminal-like domain THITH_16635 4a68f97c39e4e21504ab2ee3e69f6351 425 SMART SM00530 79 135 4.8E-11 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_16635 4a68f97c39e4e21504ab2ee3e69f6351 425 Gene3D G3DSA:1.10.260.40 66 141 1.1E-10 T 13-10-2018 THITH_16635 4a68f97c39e4e21504ab2ee3e69f6351 425 SUPERFAMILY SSF47413 74 139 1.47E-11 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 THITH_16635 4a68f97c39e4e21504ab2ee3e69f6351 425 Pfam PF01381 Helix-turn-helix 82 134 2.1E-10 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_14270 d55ebcc377fed6b3c9beb386677270d4 90 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 7.8E-23 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14270 d55ebcc377fed6b3c9beb386677270d4 90 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 7.8E-23 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14270 d55ebcc377fed6b3c9beb386677270d4 90 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 7.8E-23 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14270 d55ebcc377fed6b3c9beb386677270d4 90 SUPERFAMILY SSF54570 3 83 1.96E-34 T 13-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14270 d55ebcc377fed6b3c9beb386677270d4 90 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 89 6.4E-45 T 13-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 THITH_14270 d55ebcc377fed6b3c9beb386677270d4 90 PIRSF PIRSF002144 1 90 1.5E-31 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14270 d55ebcc377fed6b3c9beb386677270d4 90 Gene3D G3DSA:3.30.860.10 1 90 2.1E-39 T 13-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14270 d55ebcc377fed6b3c9beb386677270d4 90 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 13-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14270 d55ebcc377fed6b3c9beb386677270d4 90 Pfam PF00203 Ribosomal protein S19 3 83 7.8E-36 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14270 d55ebcc377fed6b3c9beb386677270d4 90 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.035 T 13-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_04690 bbc28e41bfcb9e6a87695827255c5b16 92 Gene3D G3DSA:3.10.450.530 1 86 3.2E-8 T 13-10-2018 IPR038573 Ribonuclease toxin BrnT superfamily THITH_04690 bbc28e41bfcb9e6a87695827255c5b16 92 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 8 83 1.6E-21 T 13-10-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system THITH_03965 2d30d6dbe8757be63e0df1b3b42208ac 166 SUPERFAMILY SSF75169 41 164 4.3E-12 T 13-10-2018 IPR027396 DsrEFH-like THITH_03965 2d30d6dbe8757be63e0df1b3b42208ac 166 Gene3D G3DSA:3.40.1260.10 39 164 5.7E-10 T 13-10-2018 IPR027396 DsrEFH-like THITH_03965 2d30d6dbe8757be63e0df1b3b42208ac 166 Pfam PF02635 DsrE/DsrF-like family 41 163 1.9E-8 T 13-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THITH_02930 d6699de65294c75f1d343d2debabe760 195 PRINTS PR01021 OMPA domain signature 121 136 4.9E-15 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THITH_02930 d6699de65294c75f1d343d2debabe760 195 PRINTS PR01021 OMPA domain signature 136 152 4.9E-15 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THITH_02930 d6699de65294c75f1d343d2debabe760 195 PRINTS PR01021 OMPA domain signature 91 113 4.9E-15 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THITH_02930 d6699de65294c75f1d343d2debabe760 195 Gene3D G3DSA:3.30.1330.60 73 193 2.1E-38 T 13-10-2018 IPR036737 OmpA-like domain superfamily THITH_02930 d6699de65294c75f1d343d2debabe760 195 SUPERFAMILY SSF103088 78 190 2.09E-33 T 13-10-2018 IPR036737 OmpA-like domain superfamily THITH_02930 d6699de65294c75f1d343d2debabe760 195 Pfam PF00691 OmpA family 90 185 3.9E-16 T 13-10-2018 IPR006665 OmpA-like domain THITH_02930 d6699de65294c75f1d343d2debabe760 195 Hamap MF_02204 Peptidoglycan-associated lipoprotein [pal]. 1 191 29.897 T 13-10-2018 IPR039001 Peptidoglycan-associated lipoprotein GO:0009279|GO:0051301 THITH_02930 d6699de65294c75f1d343d2debabe760 195 TIGRFAM TIGR02802 Pal_lipo: peptidoglycan-associated lipoprotein 89 191 1.6E-41 T 13-10-2018 IPR014169 Peptidoglycan-associated lipoprotein, C-terminal GO:0009279 THITH_14045 998df143ce0ade0652d264b5d35aa54e 425 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 331 352 - T 13-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 THITH_14045 998df143ce0ade0652d264b5d35aa54e 425 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 21 414 9.4E-150 T 13-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 THITH_14045 998df143ce0ade0652d264b5d35aa54e 425 Gene3D G3DSA:3.40.309.10 234 382 3.9E-163 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 THITH_14045 998df143ce0ade0652d264b5d35aa54e 425 Gene3D G3DSA:3.40.605.10 26 419 3.9E-163 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 THITH_14045 998df143ce0ade0652d264b5d35aa54e 425 SUPERFAMILY SSF53720 14 424 3.67E-120 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 THITH_14045 998df143ce0ade0652d264b5d35aa54e 425 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 13 424 42.087 T 13-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 THITH_14045 998df143ce0ade0652d264b5d35aa54e 425 Pfam PF00171 Aldehyde dehydrogenase family 19 292 2.2E-15 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 THITH_14045 998df143ce0ade0652d264b5d35aa54e 425 Pfam PF00171 Aldehyde dehydrogenase family 318 381 9.8E-6 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 THITH_14045 998df143ce0ade0652d264b5d35aa54e 425 PIRSF PIRSF000151 7 425 8.6E-176 T 13-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 THITH_07720 d1f9102cfe908f8d59419c22c4c586ef 342 Gene3D G3DSA:3.90.550.10 1 197 1.6E-46 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_07720 d1f9102cfe908f8d59419c22c4c586ef 342 Pfam PF00535 Glycosyl transferase family 2 2 124 2.5E-34 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THITH_07720 d1f9102cfe908f8d59419c22c4c586ef 342 SUPERFAMILY SSF53448 1 227 4.86E-52 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_12685 475a57f5eea57882d6d55c23a986f5ea 112 SUPERFAMILY SSF46626 14 109 1.19E-8 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_12685 475a57f5eea57882d6d55c23a986f5ea 112 Gene3D G3DSA:1.10.760.10 24 112 7.5E-6 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_12685 475a57f5eea57882d6d55c23a986f5ea 112 Pfam PF00034 Cytochrome c 26 110 1.9E-4 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_14970 14a565af550ee7480d1778e6cd38627b 175 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 3 168 4.8E-59 T 13-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 THITH_14970 14a565af550ee7480d1778e6cd38627b 175 SUPERFAMILY SSF52540 3 169 1.13E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14970 14a565af550ee7480d1778e6cd38627b 175 PIRSF PIRSF006135 1 171 6.7E-53 T 13-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 THITH_14970 14a565af550ee7480d1778e6cd38627b 175 Gene3D G3DSA:3.40.50.300 2 169 6.9E-56 T 13-10-2018 THITH_08375 65a6c2d45e939f6a5746770059972357 285 Pfam PF00378 Enoyl-CoA hydratase/isomerase 32 279 3.8E-81 T 13-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 THITH_08375 65a6c2d45e939f6a5746770059972357 285 Gene3D G3DSA:3.90.226.10 4 222 3.6E-77 T 13-10-2018 THITH_08375 65a6c2d45e939f6a5746770059972357 285 SUPERFAMILY SSF52096 21 280 1.8E-76 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THITH_08375 65a6c2d45e939f6a5746770059972357 285 Gene3D G3DSA:1.10.12.10 223 273 4.8E-29 T 13-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal THITH_08375 65a6c2d45e939f6a5746770059972357 285 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 17 284 54.619 T 13-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 THITH_08375 65a6c2d45e939f6a5746770059972357 285 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 123 143 - T 13-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 THITH_08375 65a6c2d45e939f6a5746770059972357 285 TIGRFAM TIGR01929 menB: naphthoate synthase 24 281 1.0E-139 T 13-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 THITH_08990 0faf4bcf68f3ea7f6beb381413be78b2 103 Gene3D G3DSA:1.10.760.10 30 101 2.7E-13 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_08990 0faf4bcf68f3ea7f6beb381413be78b2 103 SUPERFAMILY SSF46626 27 100 3.58E-13 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_14555 4a934fe425e23c98c0de9e7447673c1f 469 PIRSF PIRSF038885 6 407 2.0E-152 T 13-10-2018 IPR030689 Cytochrome b GO:0006122|GO:0008121|GO:0009055|GO:0045275 Reactome: R-HSA-611105 THITH_14555 4a934fe425e23c98c0de9e7447673c1f 469 SUPERFAMILY SSF81648 289 398 1.16E-25 T 13-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 THITH_14555 4a934fe425e23c98c0de9e7447673c1f 469 SUPERFAMILY SSF81342 22 288 7.06E-99 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THITH_14555 4a934fe425e23c98c0de9e7447673c1f 469 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 286 388 6.4E-36 T 13-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 THITH_14555 4a934fe425e23c98c0de9e7447673c1f 469 Gene3D G3DSA:1.20.810.10 4 408 1.1E-146 T 13-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 THITH_14555 4a934fe425e23c98c0de9e7447673c1f 469 Pfam PF00033 Cytochrome b/b6/petB 33 220 1.1E-69 T 13-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 THITH_14560 150692723c7daaf27bf195f785404683 200 SUPERFAMILY SSF50022 30 190 8.63E-38 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THITH_14560 150692723c7daaf27bf195f785404683 200 Pfam PF10399 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal 3 40 8.9E-13 T 13-10-2018 IPR019470 Ubiquitinol-cytochrome C reductase, Fe-S subunit, TAT signal GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 THITH_14560 150692723c7daaf27bf195f785404683 200 PRINTS PR00162 Rieske 2Fe-2S subunit signature 151 163 2.3E-5 T 13-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 THITH_14560 150692723c7daaf27bf195f785404683 200 PRINTS PR00162 Rieske 2Fe-2S subunit signature 120 131 2.3E-5 T 13-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 THITH_14560 150692723c7daaf27bf195f785404683 200 Gene3D G3DSA:2.102.10.10 43 192 1.1E-45 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THITH_14560 150692723c7daaf27bf195f785404683 200 TIGRFAM TIGR01416 Rieske_proteo: ubiquinol-cytochrome c reductase, iron-sulfur subunit 9 192 4.9E-66 T 13-10-2018 IPR006317 Ubiquinol-cytochrome c reductase, iron-sulphur subunit GO:0008121|GO:0055114 KEGG: 00190+1.10.2.2|MetaCyc: PWY-3781|MetaCyc: PWY-6692|MetaCyc: PWY-7082|MetaCyc: PWY-7279 THITH_14560 150692723c7daaf27bf195f785404683 200 Pfam PF00355 Rieske [2Fe-2S] domain 59 178 1.4E-7 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THITH_17015 5caafd1e52e18a8cebe1d08773bf017c 459 SUPERFAMILY SSF52540 75 345 1.05E-91 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_17015 5caafd1e52e18a8cebe1d08773bf017c 459 SUPERFAMILY SSF50615 2 72 1.18E-23 T 13-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_17015 5caafd1e52e18a8cebe1d08773bf017c 459 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 458 56.264 T 13-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 THITH_17015 5caafd1e52e18a8cebe1d08773bf017c 459 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 458 8.0E-255 T 13-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 THITH_17015 5caafd1e52e18a8cebe1d08773bf017c 459 SUPERFAMILY SSF47917 343 458 7.06E-54 T 13-10-2018 THITH_17015 5caafd1e52e18a8cebe1d08773bf017c 459 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 128 340 1.1E-65 T 13-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_17015 5caafd1e52e18a8cebe1d08773bf017c 459 SMART SM00382 140 403 0.0017 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_17015 5caafd1e52e18a8cebe1d08773bf017c 459 Gene3D G3DSA:3.40.50.300 74 342 2.1E-112 T 13-10-2018 THITH_17015 5caafd1e52e18a8cebe1d08773bf017c 459 Gene3D G3DSA:1.10.1140.10 343 459 1.6E-60 T 13-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_17015 5caafd1e52e18a8cebe1d08773bf017c 459 Gene3D G3DSA:2.40.10.170 1 73 7.0E-28 T 13-10-2018 THITH_17015 5caafd1e52e18a8cebe1d08773bf017c 459 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 71 4.1E-21 T 13-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_17015 5caafd1e52e18a8cebe1d08773bf017c 459 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 331 340 - T 13-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 THITH_16415 62e750366cb6fff4b7ec3656b577f300 242 SMART SM00421 144 201 3.5E-22 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_16415 62e750366cb6fff4b7ec3656b577f300 242 SUPERFAMILY SSF46894 141 206 6.46E-21 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THITH_16415 62e750366cb6fff4b7ec3656b577f300 242 SMART SM00448 1 111 6.3E-25 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_16415 62e750366cb6fff4b7ec3656b577f300 242 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 2.9E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_16415 62e750366cb6fff4b7ec3656b577f300 242 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 2.9E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_16415 62e750366cb6fff4b7ec3656b577f300 242 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 2.9E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_16415 62e750366cb6fff4b7ec3656b577f300 242 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 200 2.8E-21 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_16415 62e750366cb6fff4b7ec3656b577f300 242 Pfam PF00072 Response regulator receiver domain 1 111 5.1E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_16415 62e750366cb6fff4b7ec3656b577f300 242 ProSitePatterns PS00622 LuxR-type HTH domain signature. 161 188 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_16415 62e750366cb6fff4b7ec3656b577f300 242 Gene3D G3DSA:3.40.50.12740 1 206 2.6E-60 T 13-10-2018 THITH_16415 62e750366cb6fff4b7ec3656b577f300 242 SUPERFAMILY SSF52172 1 123 1.57E-30 T 13-10-2018 IPR011006 CheY-like superfamily THITH_09445 8a8347c2b35708a6056460cc52879ad2 125 SUPERFAMILY SSF81343 3 123 1.68E-25 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_09445 8a8347c2b35708a6056460cc52879ad2 125 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 6 119 1.6E-24 T 13-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_09445 8a8347c2b35708a6056460cc52879ad2 125 ProSitePatterns PS01000 Succinate dehydrogenase cytochrome b subunit signature 1. 6 30 - T 13-10-2018 IPR018495 Succinate dehydrogenase, cytochrome b subunit, conserved site GO:0000104|GO:0006099|GO:0009055|GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_09445 8a8347c2b35708a6056460cc52879ad2 125 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 6 122 2.0E-32 T 13-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_09445 8a8347c2b35708a6056460cc52879ad2 125 Gene3D G3DSA:1.20.1300.10 2 124 3.6E-34 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_09445 8a8347c2b35708a6056460cc52879ad2 125 PIRSF PIRSF000178 1 125 6.8E-25 T 13-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_13835 abcceb09adb8675f450040297c55c168 179 Gene3D G3DSA:1.10.60.30 22 96 5.4E-25 T 13-10-2018 THITH_13835 abcceb09adb8675f450040297c55c168 179 Gene3D G3DSA:1.10.60.30 98 166 5.3E-28 T 13-10-2018 THITH_13835 abcceb09adb8675f450040297c55c168 179 SUPERFAMILY SSF158710 23 160 1.31E-47 T 13-10-2018 IPR023153 PSPTO4464-like domain superfamily THITH_13835 abcceb09adb8675f450040297c55c168 179 Pfam PF04751 Protein of unknown function (DUF615) 11 160 2.1E-55 T 13-10-2018 IPR006839 Ribosome-associated, YjgA THITH_13835 abcceb09adb8675f450040297c55c168 179 PIRSF PIRSF016183 1 165 1.1E-59 T 13-10-2018 IPR006839 Ribosome-associated, YjgA THITH_10805 a037ddffe1414a0d47f62d953ded583b 566 Pfam PF08502 LeuA allosteric (dimerisation) domain 423 550 1.3E-16 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THITH_10805 a037ddffe1414a0d47f62d953ded583b 566 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 40 56 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THITH_10805 a037ddffe1414a0d47f62d953ded583b 566 SMART SM00917 423 552 4.1E-17 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THITH_10805 a037ddffe1414a0d47f62d953ded583b 566 SUPERFAMILY SSF89000 389 438 6.28E-11 T 13-10-2018 THITH_10805 a037ddffe1414a0d47f62d953ded583b 566 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 5 553 49.806 T 13-10-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THITH_10805 a037ddffe1414a0d47f62d953ded583b 566 Pfam PF00682 HMGL-like 35 311 1.2E-70 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 THITH_10805 a037ddffe1414a0d47f62d953ded583b 566 SUPERFAMILY SSF51569 22 330 3.48E-95 T 13-10-2018 THITH_10805 a037ddffe1414a0d47f62d953ded583b 566 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 243 256 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THITH_10805 a037ddffe1414a0d47f62d953ded583b 566 Gene3D G3DSA:3.20.20.70 13 377 4.7E-146 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_10805 a037ddffe1414a0d47f62d953ded583b 566 Gene3D G3DSA:3.30.160.270 378 551 5.1E-40 T 13-10-2018 THITH_10805 a037ddffe1414a0d47f62d953ded583b 566 SUPERFAMILY SSF110921 444 550 1.57E-21 T 13-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THITH_13015 420226c13ce201b27753b340edb0a972 289 Pfam PF00809 Pterin binding enzyme 22 262 1.4E-87 T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_13015 420226c13ce201b27753b340edb0a972 289 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 55 68 - T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_13015 420226c13ce201b27753b340edb0a972 289 SUPERFAMILY SSF51717 9 278 8.9E-105 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_13015 420226c13ce201b27753b340edb0a972 289 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 21 36 - T 13-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_13015 420226c13ce201b27753b340edb0a972 289 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 21 276 1.2E-99 T 13-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 THITH_13015 420226c13ce201b27753b340edb0a972 289 Gene3D G3DSA:3.20.20.20 2 283 1.7E-111 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_11675 551f1c997003c3f2c5aa34c1e6c7b61d 299 Pfam PF13247 4Fe-4S dicluster domain 88 184 1.2E-22 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_11675 551f1c997003c3f2c5aa34c1e6c7b61d 299 SUPERFAMILY SSF81597 242 285 3.27E-9 T 13-10-2018 THITH_11675 551f1c997003c3f2c5aa34c1e6c7b61d 299 SUPERFAMILY SSF54862 25 248 7.53E-67 T 13-10-2018 THITH_11675 551f1c997003c3f2c5aa34c1e6c7b61d 299 Pfam PF09163 Formate dehydrogenase N, transmembrane 242 284 3.2E-16 T 13-10-2018 IPR015246 Formate dehydrogenase, transmembrane THITH_11675 551f1c997003c3f2c5aa34c1e6c7b61d 299 Gene3D G3DSA:1.20.5.480 243 289 1.9E-10 T 13-10-2018 IPR038384 Formate dehydrogenase, C-terminal domain superfamily THITH_11675 551f1c997003c3f2c5aa34c1e6c7b61d 299 Gene3D G3DSA:3.30.70.20 23 223 2.7E-93 T 13-10-2018 THITH_11675 551f1c997003c3f2c5aa34c1e6c7b61d 299 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 129 140 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_11675 551f1c997003c3f2c5aa34c1e6c7b61d 299 TIGRFAM TIGR01582 FDH-beta: formate dehydrogenase, beta subunit 5 285 1.6E-142 T 13-10-2018 IPR006470 Formate dehydrogenase iron-sulphur subunit, Proteobacteria GO:0015944|GO:0016021|GO:0045333|GO:0051539 THITH_11675 551f1c997003c3f2c5aa34c1e6c7b61d 299 PIRSF PIRSF036298 1 299 2.7E-149 T 13-10-2018 IPR014603 Formate dehydrogenase iron-sulphur subunit GO:0015944|GO:0045333|GO:0051539 THITH_11675 551f1c997003c3f2c5aa34c1e6c7b61d 299 Gene3D G3DSA:3.30.70.20 18 158 2.7E-93 T 13-10-2018 THITH_07605 a40c6935ebf26ed7063f87ee630229ab 468 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 9 20 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_07605 a40c6935ebf26ed7063f87ee630229ab 468 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 3 304 2.3E-108 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 THITH_07605 a40c6935ebf26ed7063f87ee630229ab 468 Gene3D G3DSA:3.40.50.620 1 312 9.1E-136 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_07605 a40c6935ebf26ed7063f87ee630229ab 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 194 202 2.8E-27 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THITH_07605 a40c6935ebf26ed7063f87ee630229ab 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 20 31 2.8E-27 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THITH_07605 a40c6935ebf26ed7063f87ee630229ab 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 178 188 2.8E-27 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THITH_07605 a40c6935ebf26ed7063f87ee630229ab 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 6 18 2.8E-27 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THITH_07605 a40c6935ebf26ed7063f87ee630229ab 468 PRINTS PR00987 Glutamyl-tRNA synthetase signature 35 48 2.8E-27 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THITH_07605 a40c6935ebf26ed7063f87ee630229ab 468 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 2 460 32.499 T 13-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 THITH_07605 a40c6935ebf26ed7063f87ee630229ab 468 SUPERFAMILY SSF52374 3 295 4.02E-114 T 13-10-2018 THITH_07605 a40c6935ebf26ed7063f87ee630229ab 468 SUPERFAMILY SSF48163 298 459 5.1E-42 T 13-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 THITH_07605 a40c6935ebf26ed7063f87ee630229ab 468 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 3 458 1.4E-176 T 13-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 THITH_07605 a40c6935ebf26ed7063f87ee630229ab 468 Gene3D G3DSA:1.10.10.350 366 466 4.5E-25 T 13-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 THITH_04955 ea0875bbb8d4d7c98d3817325a8ee832 467 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 39 204 3.2E-15 T 13-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 THITH_04955 ea0875bbb8d4d7c98d3817325a8ee832 467 SUPERFAMILY SSF52540 33 266 8.42E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_04955 ea0875bbb8d4d7c98d3817325a8ee832 467 SMART SM00382 71 188 2.0E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_04955 ea0875bbb8d4d7c98d3817325a8ee832 467 Gene3D G3DSA:1.10.8.60 190 258 8.0E-15 T 13-10-2018 THITH_04955 ea0875bbb8d4d7c98d3817325a8ee832 467 Gene3D G3DSA:1.10.3710.10 364 463 2.1E-31 T 13-10-2018 THITH_04955 ea0875bbb8d4d7c98d3817325a8ee832 467 Pfam PF16193 AAA C-terminal domain 212 285 5.4E-22 T 13-10-2018 IPR032423 AAA C-terminal domain THITH_04955 ea0875bbb8d4d7c98d3817325a8ee832 467 Gene3D G3DSA:1.20.272.10 259 363 6.5E-38 T 13-10-2018 THITH_04955 ea0875bbb8d4d7c98d3817325a8ee832 467 SUPERFAMILY SSF48019 270 451 1.7E-68 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 THITH_04955 ea0875bbb8d4d7c98d3817325a8ee832 467 Pfam PF12002 MgsA AAA+ ATPase C terminal 286 451 1.6E-59 T 13-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal THITH_04955 ea0875bbb8d4d7c98d3817325a8ee832 467 Gene3D G3DSA:3.40.50.300 31 187 1.9E-42 T 13-10-2018 THITH_04970 c7b5be24cdcfc852c73b51cd9d4e6dac 468 Pfam PF02321 Outer membrane efflux protein 3 232 1.4E-12 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 THITH_04970 c7b5be24cdcfc852c73b51cd9d4e6dac 468 Pfam PF02321 Outer membrane efflux protein 261 446 5.4E-20 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 THITH_04970 c7b5be24cdcfc852c73b51cd9d4e6dac 468 Gene3D G3DSA:1.20.1600.10 1 455 8.9E-69 T 13-10-2018 THITH_04970 c7b5be24cdcfc852c73b51cd9d4e6dac 468 SUPERFAMILY SSF56954 1 452 2.35E-56 T 13-10-2018 THITH_00930 160993e9c53949a8c58c2fbb0b2494d0 375 PIRSF PIRSF000729 8 375 2.8E-128 T 13-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 THITH_00930 160993e9c53949a8c58c2fbb0b2494d0 375 SUPERFAMILY SSF88697 284 374 5.08E-25 T 13-10-2018 IPR015947 PUA-like superfamily THITH_00930 160993e9c53949a8c58c2fbb0b2494d0 375 Hamap MF_00456 Glutamate 5-kinase [proB]. 12 266 35.249 T 13-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 THITH_00930 160993e9c53949a8c58c2fbb0b2494d0 375 ProSitePatterns PS00902 Glutamate 5-kinase signature. 214 231 - T 13-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 THITH_00930 160993e9c53949a8c58c2fbb0b2494d0 375 Pfam PF01472 PUA domain 285 358 2.3E-22 T 13-10-2018 IPR002478 PUA domain GO:0003723 THITH_00930 160993e9c53949a8c58c2fbb0b2494d0 375 Gene3D G3DSA:2.30.130.10 273 375 1.4E-33 T 13-10-2018 IPR036974 PUA domain superfamily GO:0003723 THITH_00930 160993e9c53949a8c58c2fbb0b2494d0 375 Pfam PF00696 Amino acid kinase family 13 240 3.8E-43 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 THITH_00930 160993e9c53949a8c58c2fbb0b2494d0 375 SMART SM00359 284 367 5.0E-17 T 13-10-2018 IPR002478 PUA domain GO:0003723 THITH_00930 160993e9c53949a8c58c2fbb0b2494d0 375 SUPERFAMILY SSF53633 12 264 1.44E-66 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THITH_00930 160993e9c53949a8c58c2fbb0b2494d0 375 Gene3D G3DSA:3.40.1160.10 1 272 1.1E-88 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THITH_00930 160993e9c53949a8c58c2fbb0b2494d0 375 TIGRFAM TIGR01027 proB: glutamate 5-kinase 12 373 1.3E-127 T 13-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 THITH_00930 160993e9c53949a8c58c2fbb0b2494d0 375 PRINTS PR00474 Glutamate 5-kinase family signature 83 111 8.8E-51 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THITH_00930 160993e9c53949a8c58c2fbb0b2494d0 375 PRINTS PR00474 Glutamate 5-kinase family signature 49 63 8.8E-51 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THITH_00930 160993e9c53949a8c58c2fbb0b2494d0 375 PRINTS PR00474 Glutamate 5-kinase family signature 123 144 8.8E-51 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THITH_00930 160993e9c53949a8c58c2fbb0b2494d0 375 PRINTS PR00474 Glutamate 5-kinase family signature 155 182 8.8E-51 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THITH_00930 160993e9c53949a8c58c2fbb0b2494d0 375 PRINTS PR00474 Glutamate 5-kinase family signature 216 236 8.8E-51 T 13-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 THITH_07415 3478a1150dd33295c450c68ca388081b 582 Gene3D G3DSA:3.90.226.10 296 547 1.9E-26 T 13-10-2018 THITH_07415 3478a1150dd33295c450c68ca388081b 582 SUPERFAMILY SSF52096 296 537 7.11E-31 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THITH_07415 3478a1150dd33295c450c68ca388081b 582 PIRSF PIRSF006787 1 580 2.3E-249 T 13-10-2018 IPR009188 [NiFe]-hydrogenase maturation factor, HypX/HoxX type THITH_07415 3478a1150dd33295c450c68ca388081b 582 SUPERFAMILY SSF50486 175 262 2.16E-12 T 13-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 THITH_07415 3478a1150dd33295c450c68ca388081b 582 Gene3D G3DSA:3.40.50.170 19 164 4.8E-16 T 13-10-2018 THITH_07415 3478a1150dd33295c450c68ca388081b 582 SUPERFAMILY SSF53328 3 158 4.06E-24 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THITH_07415 3478a1150dd33295c450c68ca388081b 582 Pfam PF00551 Formyl transferase 40 139 1.1E-5 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THITH_07415 3478a1150dd33295c450c68ca388081b 582 Pfam PF02911 Formyl transferase, C-terminal domain 174 258 1.6E-8 T 13-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THITH_07415 3478a1150dd33295c450c68ca388081b 582 Gene3D G3DSA:3.10.25.10 177 270 7.5E-7 T 13-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THITH_07415 3478a1150dd33295c450c68ca388081b 582 Pfam PF00378 Enoyl-CoA hydratase/isomerase 328 507 4.1E-16 T 13-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 THITH_14330 a0f420acedc07a61b364e43bd571f98e 125 Gene3D G3DSA:1.20.5.710 2 54 4.7E-19 T 13-10-2018 THITH_14330 a0f420acedc07a61b364e43bd571f98e 125 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 59 125 4.4E-32 T 13-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14330 a0f420acedc07a61b364e43bd571f98e 125 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 5 49 3.1E-18 T 13-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14330 a0f420acedc07a61b364e43bd571f98e 125 SUPERFAMILY SSF54736 56 125 5.58E-25 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like THITH_14330 a0f420acedc07a61b364e43bd571f98e 125 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 125 1.3E-46 T 13-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14330 a0f420acedc07a61b364e43bd571f98e 125 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 61 99 4.0E-12 T 13-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14330 a0f420acedc07a61b364e43bd571f98e 125 SUPERFAMILY SSF48300 4 61 2.09E-15 T 13-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14330 a0f420acedc07a61b364e43bd571f98e 125 Gene3D G3DSA:3.30.1390.10 55 125 5.6E-31 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like THITH_14330 a0f420acedc07a61b364e43bd571f98e 125 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 2 125 25.446 T 13-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03015 255f810ad333b5c8a126b5bc512dae69 331 Gene3D G3DSA:1.20.1630.10 13 314 1.1E-22 T 13-10-2018 THITH_03015 255f810ad333b5c8a126b5bc512dae69 331 Pfam PF03916 Polysulphide reductase, NrfD 19 311 6.8E-37 T 13-10-2018 IPR005614 NrfD family THITH_12695 3e2dd1e1ef1dfa94ff96f267801285ac 576 Gene3D G3DSA:1.25.40.10 357 576 7.0E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_12695 3e2dd1e1ef1dfa94ff96f267801285ac 576 Gene3D G3DSA:1.25.40.10 50 356 1.4E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_12695 3e2dd1e1ef1dfa94ff96f267801285ac 576 SUPERFAMILY SSF48452 454 573 8.35E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_12695 3e2dd1e1ef1dfa94ff96f267801285ac 576 SUPERFAMILY SSF48452 228 441 1.9E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_05215 146d197bf2229d88aebf328f193961f6 324 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 4 318 1.3E-66 T 13-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THITH_05215 146d197bf2229d88aebf328f193961f6 324 Gene3D G3DSA:1.20.120.920 82 323 5.2E-54 T 13-10-2018 THITH_05215 146d197bf2229d88aebf328f193961f6 324 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 1 309 21.515 T 13-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THITH_05215 146d197bf2229d88aebf328f193961f6 324 Gene3D G3DSA:3.100.10.20 1 79 3.9E-16 T 13-10-2018 THITH_05215 146d197bf2229d88aebf328f193961f6 324 Pfam PF01867 CRISPR associated protein Cas1 4 282 7.6E-72 T 13-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THITH_08405 c8aba22dd285a30dd7bf7821153ff02c 272 Pfam PF07728 AAA domain (dynein-related subfamily) 39 173 2.5E-36 T 13-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 THITH_08405 c8aba22dd285a30dd7bf7821153ff02c 272 Gene3D G3DSA:3.40.50.300 25 191 8.2E-31 T 13-10-2018 THITH_08405 c8aba22dd285a30dd7bf7821153ff02c 272 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 186 268 2.2E-30 T 13-10-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal THITH_08405 c8aba22dd285a30dd7bf7821153ff02c 272 SUPERFAMILY SSF52540 30 238 2.72E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_07370 e524760cede64e6de0a20b3f52627e57 160 Gene3D G3DSA:3.10.50.40 3 154 5.3E-59 T 13-10-2018 THITH_07370 e524760cede64e6de0a20b3f52627e57 160 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 4 136 5.6E-14 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain THITH_07370 e524760cede64e6de0a20b3f52627e57 160 Gene3D G3DSA:2.40.10.330 71 121 5.3E-59 T 13-10-2018 THITH_07370 e524760cede64e6de0a20b3f52627e57 160 SUPERFAMILY SSF54534 3 140 8.05E-37 T 13-10-2018 THITH_00420 53b9f35937f41452444aead486d19062 451 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 92 101 - T 13-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_00420 53b9f35937f41452444aead486d19062 451 SUPERFAMILY SSF53738 257 361 5.1E-31 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_00420 53b9f35937f41452444aead486d19062 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 91 105 1.1E-28 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_00420 53b9f35937f41452444aead486d19062 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 168 187 1.1E-28 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_00420 53b9f35937f41452444aead486d19062 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 232 247 1.1E-28 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_00420 53b9f35937f41452444aead486d19062 451 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 203 216 1.1E-28 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_00420 53b9f35937f41452444aead486d19062 451 SUPERFAMILY SSF53738 152 255 9.42E-26 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_00420 53b9f35937f41452444aead486d19062 451 Gene3D G3DSA:3.40.120.10 249 365 5.3E-33 T 13-10-2018 THITH_00420 53b9f35937f41452444aead486d19062 451 SUPERFAMILY SSF55957 367 450 2.79E-20 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_00420 53b9f35937f41452444aead486d19062 451 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 133 1.3E-30 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_00420 53b9f35937f41452444aead486d19062 451 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 366 5.7E-23 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_00420 53b9f35937f41452444aead486d19062 451 Gene3D G3DSA:3.40.120.10 2 143 1.6E-49 T 13-10-2018 THITH_00420 53b9f35937f41452444aead486d19062 451 Gene3D G3DSA:3.30.310.50 368 450 4.9E-27 T 13-10-2018 THITH_00420 53b9f35937f41452444aead486d19062 451 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 152 252 8.0E-22 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_00420 53b9f35937f41452444aead486d19062 451 Gene3D G3DSA:3.40.120.10 170 248 3.6E-26 T 13-10-2018 THITH_00420 53b9f35937f41452444aead486d19062 451 SUPERFAMILY SSF53738 5 175 8.24E-35 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_00420 53b9f35937f41452444aead486d19062 451 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 372 449 5.1E-12 T 13-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_02650 67536b1839c502dcb399ce9ea9d85495 197 Pfam PF12007 Protein of unknown function (DUF3501) 3 193 6.2E-73 T 13-10-2018 IPR021890 Protein of unknown function DUF3501 THITH_14640 4bca332e8fffe4ee8e0d0c8211d383bb 179 Gene3D G3DSA:3.40.50.1000 4 175 1.6E-53 T 13-10-2018 IPR023214 HAD superfamily THITH_14640 4bca332e8fffe4ee8e0d0c8211d383bb 179 TIGRFAM TIGR01670 KdsC-phosphatas: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family 15 166 1.9E-49 T 13-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THITH_14640 4bca332e8fffe4ee8e0d0c8211d383bb 179 Pfam PF08282 haloacid dehalogenase-like hydrolase 86 148 2.5E-8 T 13-10-2018 THITH_14640 4bca332e8fffe4ee8e0d0c8211d383bb 179 PIRSF PIRSF006118 3 177 9.2E-64 T 13-10-2018 IPR010023 KdsC family GO:0016788 KEGG: 00540+3.1.3.45|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THITH_14640 4bca332e8fffe4ee8e0d0c8211d383bb 179 SUPERFAMILY SSF56784 13 173 7.89E-44 T 13-10-2018 IPR036412 HAD-like superfamily THITH_14295 90f3bc9ffbfee88f15bd26fa13add257 103 SUPERFAMILY SSF54999 5 101 6.8E-37 T 13-10-2018 IPR036838 Ribosomal protein S10 domain superfamily THITH_14295 90f3bc9ffbfee88f15bd26fa13add257 103 Gene3D G3DSA:3.30.70.600 1 103 8.9E-38 T 13-10-2018 IPR036838 Ribosomal protein S10 domain superfamily THITH_14295 90f3bc9ffbfee88f15bd26fa13add257 103 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 6.0E-45 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14295 90f3bc9ffbfee88f15bd26fa13add257 103 SMART SM01403 7 101 2.0E-56 T 13-10-2018 IPR027486 Ribosomal protein S10 domain THITH_14295 90f3bc9ffbfee88f15bd26fa13add257 103 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 13-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14295 90f3bc9ffbfee88f15bd26fa13add257 103 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 27.175 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14295 90f3bc9ffbfee88f15bd26fa13add257 103 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 5.9E-19 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14295 90f3bc9ffbfee88f15bd26fa13add257 103 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 5.9E-19 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14295 90f3bc9ffbfee88f15bd26fa13add257 103 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 5.9E-19 T 13-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14295 90f3bc9ffbfee88f15bd26fa13add257 103 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 8.3E-35 T 13-10-2018 IPR027486 Ribosomal protein S10 domain THITH_01995 659f09198ca8c2b54c7adac00a05739e 96 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 8 90 3.3E-31 T 13-10-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 THITH_15545 f8417ac18cbeb63eda3e0e6c7d753e87 336 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 23 307 7.7E-69 T 13-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 THITH_15545 f8417ac18cbeb63eda3e0e6c7d753e87 336 PIRSF PIRSF026649 13 316 2.6E-82 T 13-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 THITH_07850 93677436d8ef3aebe72252016133d6bd 693 SUPERFAMILY SSF47384 464 523 4.12E-5 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_07850 93677436d8ef3aebe72252016133d6bd 693 Gene3D G3DSA:1.10.3210.10 9 249 1.0E-38 T 13-10-2018 THITH_07850 93677436d8ef3aebe72252016133d6bd 693 Pfam PF08668 HDOD domain 11 205 3.6E-28 T 13-10-2018 IPR013976 Metal-dependent hydrolase HDOD THITH_07850 93677436d8ef3aebe72252016133d6bd 693 PRINTS PR00344 Bacterial sensor protein C-terminal signature 645 663 3.6E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_07850 93677436d8ef3aebe72252016133d6bd 693 PRINTS PR00344 Bacterial sensor protein C-terminal signature 633 643 3.6E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_07850 93677436d8ef3aebe72252016133d6bd 693 PRINTS PR00344 Bacterial sensor protein C-terminal signature 668 681 3.6E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_07850 93677436d8ef3aebe72252016133d6bd 693 PRINTS PR00344 Bacterial sensor protein C-terminal signature 615 629 3.6E-13 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_07850 93677436d8ef3aebe72252016133d6bd 693 Gene3D G3DSA:1.10.287.130 472 526 2.5E-7 T 13-10-2018 THITH_07850 93677436d8ef3aebe72252016133d6bd 693 Gene3D G3DSA:3.30.565.10 529 685 1.6E-34 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_07850 93677436d8ef3aebe72252016133d6bd 693 SMART SM00387 573 684 6.6E-30 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_07850 93677436d8ef3aebe72252016133d6bd 693 SUPERFAMILY SSF55874 536 681 1.83E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_07850 93677436d8ef3aebe72252016133d6bd 693 SUPERFAMILY SSF55781 311 448 3.43E-8 T 13-10-2018 THITH_07850 93677436d8ef3aebe72252016133d6bd 693 Gene3D G3DSA:3.30.450.40 291 445 2.5E-6 T 13-10-2018 IPR029016 GAF-like domain superfamily THITH_07850 93677436d8ef3aebe72252016133d6bd 693 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 576 681 2.5E-19 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_07850 93677436d8ef3aebe72252016133d6bd 693 SUPERFAMILY SSF109604 11 263 4.71E-34 T 13-10-2018 THITH_06500 162bf330783a6941df0b601ffeab0fa2 250 SUPERFAMILY SSF56112 12 167 1.35E-9 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily THITH_06500 162bf330783a6941df0b601ffeab0fa2 250 Gene3D G3DSA:1.10.510.10 103 197 7.2E-6 T 13-10-2018 THITH_06500 162bf330783a6941df0b601ffeab0fa2 250 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 139 151 - T 13-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 THITH_04605 8a062922e882c7698d67a35e872dab60 558 Pfam PF03050 Transposase IS66 family 209 500 7.7E-96 T 13-10-2018 IPR004291 Transposase, IS66 THITH_04605 8a062922e882c7698d67a35e872dab60 558 Pfam PF13007 Transposase C of IS166 homeodomain 61 136 3.2E-13 T 13-10-2018 IPR024463 Transposase TnpC, homeodomain THITH_04605 8a062922e882c7698d67a35e872dab60 558 Pfam PF13817 IS66 C-terminal element 506 544 4.0E-12 T 13-10-2018 IPR039552 Transposase IS66, C-terminal THITH_15445 8a062922e882c7698d67a35e872dab60 558 Pfam PF03050 Transposase IS66 family 209 500 7.7E-96 T 13-10-2018 IPR004291 Transposase, IS66 THITH_15445 8a062922e882c7698d67a35e872dab60 558 Pfam PF13007 Transposase C of IS166 homeodomain 61 136 3.2E-13 T 13-10-2018 IPR024463 Transposase TnpC, homeodomain THITH_15445 8a062922e882c7698d67a35e872dab60 558 Pfam PF13817 IS66 C-terminal element 506 544 4.0E-12 T 13-10-2018 IPR039552 Transposase IS66, C-terminal THITH_02980 8a062922e882c7698d67a35e872dab60 558 Pfam PF03050 Transposase IS66 family 209 500 7.7E-96 T 13-10-2018 IPR004291 Transposase, IS66 THITH_02980 8a062922e882c7698d67a35e872dab60 558 Pfam PF13007 Transposase C of IS166 homeodomain 61 136 3.2E-13 T 13-10-2018 IPR024463 Transposase TnpC, homeodomain THITH_02980 8a062922e882c7698d67a35e872dab60 558 Pfam PF13817 IS66 C-terminal element 506 544 4.0E-12 T 13-10-2018 IPR039552 Transposase IS66, C-terminal THITH_09620 89e6be21873dd3389d635681162a65b4 236 Gene3D G3DSA:1.10.3810.10 43 231 8.5E-51 T 13-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_09620 89e6be21873dd3389d635681162a65b4 236 SUPERFAMILY SSF53955 40 218 7.03E-58 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily THITH_09620 89e6be21873dd3389d635681162a65b4 236 Pfam PF00912 Transglycosylase 51 215 1.6E-48 T 13-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_09620 89e6be21873dd3389d635681162a65b4 236 Hamap MF_00766 Biosynthetic peptidoglycan transglycosylase [mtgA]. 4 220 39.067 T 13-10-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_09620 89e6be21873dd3389d635681162a65b4 236 TIGRFAM TIGR02070 mono_pep_trsgly: monofunctional biosynthetic peptidoglycan transglycosylase 5 217 1.5E-73 T 13-10-2018 IPR011812 Biosynthetic peptidoglycan transglycosylase GO:0009252|GO:0009274|GO:0016021|GO:0016763 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_10820 6a929537ea818743f57886045478d514 84 Gene3D G3DSA:3.40.30.10 37 84 5.0E-14 T 13-10-2018 THITH_10820 6a929537ea818743f57886045478d514 84 Pfam PF00578 AhpC/TSA family 42 84 1.8E-9 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THITH_10820 6a929537ea818743f57886045478d514 84 SUPERFAMILY SSF52833 38 84 3.23E-14 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_06410 9b22f40a6c35140615988e3e022f75b4 460 SMART SM00849 13 241 1.6E-15 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_06410 9b22f40a6c35140615988e3e022f75b4 460 SUPERFAMILY SSF56281 1 437 7.08E-120 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_06410 9b22f40a6c35140615988e3e022f75b4 460 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 380 436 2.2E-10 T 13-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain THITH_06410 9b22f40a6c35140615988e3e022f75b4 460 Pfam PF10996 Beta-Casp domain 246 365 1.1E-22 T 13-10-2018 IPR022712 Beta-Casp domain THITH_06410 9b22f40a6c35140615988e3e022f75b4 460 SMART SM01027 246 365 4.8E-35 T 13-10-2018 IPR022712 Beta-Casp domain THITH_06410 9b22f40a6c35140615988e3e022f75b4 460 Gene3D G3DSA:3.40.50.10890 217 391 3.4E-128 T 13-10-2018 THITH_06410 9b22f40a6c35140615988e3e022f75b4 460 Pfam PF00753 Metallo-beta-lactamase superfamily 18 222 3.2E-17 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_06410 9b22f40a6c35140615988e3e022f75b4 460 Gene3D G3DSA:3.60.15.10 6 428 3.4E-128 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_05105 bcba4d424960b759722a77272713f54f 419 Pfam PF00464 Serine hydroxymethyltransferase 9 385 6.1E-181 T 13-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 THITH_05105 bcba4d424960b759722a77272713f54f 419 Gene3D G3DSA:3.90.1150.10 11 394 6.6E-188 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_05105 bcba4d424960b759722a77272713f54f 419 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 221 237 - T 13-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 THITH_05105 bcba4d424960b759722a77272713f54f 419 PIRSF PIRSF000412 2 418 1.3E-171 T 13-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 THITH_05105 bcba4d424960b759722a77272713f54f 419 Gene3D G3DSA:3.40.640.10 37 288 6.6E-188 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_05105 bcba4d424960b759722a77272713f54f 419 SUPERFAMILY SSF53383 4 416 4.95E-185 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_05105 bcba4d424960b759722a77272713f54f 419 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 7 416 53.518 T 13-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 THITH_14495 de3777884da818095f55d546fdd0e2d4 572 Pfam PF03717 Penicillin-binding Protein dimerisation domain 56 203 2.2E-17 T 13-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 THITH_14495 de3777884da818095f55d546fdd0e2d4 572 Gene3D G3DSA:3.30.450.330 221 547 2.0E-108 T 13-10-2018 THITH_14495 de3777884da818095f55d546fdd0e2d4 572 SUPERFAMILY SSF56601 171 557 6.96E-91 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like THITH_14495 de3777884da818095f55d546fdd0e2d4 572 SUPERFAMILY SSF56519 51 219 1.44E-44 T 13-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 THITH_14495 de3777884da818095f55d546fdd0e2d4 572 Gene3D G3DSA:3.90.1310.30 48 219 1.3E-46 T 13-10-2018 THITH_14495 de3777884da818095f55d546fdd0e2d4 572 Hamap MF_02080 Peptidoglycan D,D-transpeptidase FtsI [ftsI]. 8 558 42.288 T 13-10-2018 IPR037532 Peptidoglycan D,D-transpeptidase FtsI GO:0005887|GO:0008658|GO:0008955|GO:0009252|GO:0051301 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THITH_14495 de3777884da818095f55d546fdd0e2d4 572 Pfam PF00905 Penicillin binding protein transpeptidase domain 245 542 9.6E-71 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THITH_14495 de3777884da818095f55d546fdd0e2d4 572 Gene3D G3DSA:3.40.710.10 281 464 2.0E-108 T 13-10-2018 THITH_14195 3b1f95396876e970dfc4d5a8aeb1bfc7 143 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 142 3.3E-28 T 13-10-2018 IPR021131 Ribosomal protein L18e/L15P THITH_14195 3b1f95396876e970dfc4d5a8aeb1bfc7 143 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 143 18.457 T 13-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 THITH_14195 3b1f95396876e970dfc4d5a8aeb1bfc7 143 SUPERFAMILY SSF52080 4 142 1.15E-41 T 13-10-2018 IPR036227 Ribosomal L18e/L15P superfamily THITH_14195 3b1f95396876e970dfc4d5a8aeb1bfc7 143 Gene3D G3DSA:3.100.10.10 71 143 2.1E-13 T 13-10-2018 THITH_14195 3b1f95396876e970dfc4d5a8aeb1bfc7 143 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 3 142 1.8E-43 T 13-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_00190 1d4cfc5b89f9bfd456d5144ac19ecddc 92 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 6 51 4.0E-11 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THITH_00190 1d4cfc5b89f9bfd456d5144ac19ecddc 92 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 7 52 4.3E-13 T 13-10-2018 THITH_00190 1d4cfc5b89f9bfd456d5144ac19ecddc 92 Gene3D G3DSA:3.40.1620.10 1 41 5.2E-12 T 13-10-2018 THITH_00190 1d4cfc5b89f9bfd456d5144ac19ecddc 92 SUPERFAMILY SSF143120 7 56 4.58E-11 T 13-10-2018 IPR036165 YefM-like superfamily THITH_06920 ddb2b99e73315aa0298a3a08c4bb10a6 502 SUPERFAMILY SSF48695 120 330 3.29E-19 T 13-10-2018 IPR036280 Multiheme cytochrome superfamily THITH_06920 ddb2b99e73315aa0298a3a08c4bb10a6 502 Pfam PF13435 Cytochrome c554 and c-prime 123 211 1.7E-20 T 13-10-2018 IPR023155 Cytochrome c-552/4 THITH_06920 ddb2b99e73315aa0298a3a08c4bb10a6 502 SUPERFAMILY SSF46626 21 103 1.16E-18 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_06920 ddb2b99e73315aa0298a3a08c4bb10a6 502 Gene3D G3DSA:1.10.760.10 26 104 5.4E-17 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_06920 ddb2b99e73315aa0298a3a08c4bb10a6 502 Gene3D G3DSA:1.10.1130.10 117 226 5.1E-10 T 13-10-2018 THITH_06920 ddb2b99e73315aa0298a3a08c4bb10a6 502 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 27 99 2.1E-9 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_09415 d0ac68fb95eb519be982f5c8d943073a 544 Gene3D G3DSA:3.40.120.10 189 291 1.9E-38 T 13-10-2018 THITH_09415 d0ac68fb95eb519be982f5c8d943073a 544 SUPERFAMILY SSF53738 183 292 1.77E-29 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_09415 d0ac68fb95eb519be982f5c8d943073a 544 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 295 408 2.9E-31 T 13-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_09415 d0ac68fb95eb519be982f5c8d943073a 544 SUPERFAMILY SSF53738 279 415 1.24E-37 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_09415 d0ac68fb95eb519be982f5c8d943073a 544 Gene3D G3DSA:3.30.310.50 390 544 7.4E-55 T 13-10-2018 THITH_09415 d0ac68fb95eb519be982f5c8d943073a 544 Gene3D G3DSA:3.40.120.10 2 188 7.1E-77 T 13-10-2018 THITH_09415 d0ac68fb95eb519be982f5c8d943073a 544 SUPERFAMILY SSF53738 2 208 2.94E-44 T 13-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_09415 d0ac68fb95eb519be982f5c8d943073a 544 SUPERFAMILY SSF55957 410 544 7.59E-44 T 13-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_09415 d0ac68fb95eb519be982f5c8d943073a 544 Gene3D G3DSA:3.40.120.10 292 389 7.7E-38 T 13-10-2018 THITH_09415 d0ac68fb95eb519be982f5c8d943073a 544 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 14 153 1.9E-32 T 13-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_09415 d0ac68fb95eb519be982f5c8d943073a 544 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 242 255 3.4E-22 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_09415 d0ac68fb95eb519be982f5c8d943073a 544 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 206 225 3.4E-22 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_09415 d0ac68fb95eb519be982f5c8d943073a 544 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 271 286 3.4E-22 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_09415 d0ac68fb95eb519be982f5c8d943073a 544 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 106 120 3.4E-22 T 13-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_09415 d0ac68fb95eb519be982f5c8d943073a 544 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 184 287 9.0E-13 T 13-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_09415 d0ac68fb95eb519be982f5c8d943073a 544 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 107 116 - T 13-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 THITH_09550 2eb9c10a419e6f0444f4ecc296ce11b8 405 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 16 25 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_09550 2eb9c10a419e6f0444f4ecc296ce11b8 405 Gene3D G3DSA:1.10.240.10 264 369 1.0E-36 T 13-10-2018 THITH_09550 2eb9c10a419e6f0444f4ecc296ce11b8 405 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 7 197 2.3E-56 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 THITH_09550 2eb9c10a419e6f0444f4ecc296ce11b8 405 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 149 170 3.7E-20 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 THITH_09550 2eb9c10a419e6f0444f4ecc296ce11b8 405 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 71 90 3.7E-20 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 THITH_09550 2eb9c10a419e6f0444f4ecc296ce11b8 405 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 20 36 3.7E-20 T 13-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 THITH_09550 2eb9c10a419e6f0444f4ecc296ce11b8 405 SUPERFAMILY SSF52374 9 401 8.37E-83 T 13-10-2018 THITH_09550 2eb9c10a419e6f0444f4ecc296ce11b8 405 Pfam PF00579 tRNA synthetases class I (W and Y) 7 174 4.4E-51 T 13-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_09550 2eb9c10a419e6f0444f4ecc296ce11b8 405 Pfam PF00579 tRNA synthetases class I (W and Y) 248 347 6.2E-8 T 13-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_09550 2eb9c10a419e6f0444f4ecc296ce11b8 405 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 7 402 34.854 T 13-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 THITH_09550 2eb9c10a419e6f0444f4ecc296ce11b8 405 Gene3D G3DSA:3.40.50.620 7 233 6.0E-74 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_12390 9d25fac97f0e8d9358263bcd0070a96f 1087 Pfam PF05231 MASE1 10 202 6.1E-20 T 13-10-2018 IPR007895 MASE1 THITH_12390 9d25fac97f0e8d9358263bcd0070a96f 1087 SMART SM01079 250 438 3.8E-35 T 13-10-2018 IPR006189 CHASE domain THITH_12390 9d25fac97f0e8d9358263bcd0070a96f 1087 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 655 817 5.8E-45 T 13-10-2018 IPR000160 GGDEF domain THITH_12390 9d25fac97f0e8d9358263bcd0070a96f 1087 Gene3D G3DSA:3.30.70.270 652 832 1.1E-61 T 13-10-2018 THITH_12390 9d25fac97f0e8d9358263bcd0070a96f 1087 SUPERFAMILY SSF55073 663 819 7.3E-50 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_12390 9d25fac97f0e8d9358263bcd0070a96f 1087 Pfam PF03924 CHASE domain 255 435 1.5E-34 T 13-10-2018 IPR006189 CHASE domain THITH_12390 9d25fac97f0e8d9358263bcd0070a96f 1087 SUPERFAMILY SSF55785 521 645 5.44E-5 T 13-10-2018 IPR035965 PAS domain superfamily THITH_12390 9d25fac97f0e8d9358263bcd0070a96f 1087 Pfam PF00990 Diguanylate cyclase, GGDEF domain 658 815 4.1E-52 T 13-10-2018 IPR000160 GGDEF domain THITH_12390 9d25fac97f0e8d9358263bcd0070a96f 1087 SMART SM00267 647 819 9.5E-67 T 13-10-2018 IPR000160 GGDEF domain THITH_12390 9d25fac97f0e8d9358263bcd0070a96f 1087 SUPERFAMILY SSF141868 834 1078 1.44E-91 T 13-10-2018 IPR035919 EAL domain superfamily THITH_12390 9d25fac97f0e8d9358263bcd0070a96f 1087 Gene3D G3DSA:3.20.20.450 833 1080 8.8E-105 T 13-10-2018 IPR035919 EAL domain superfamily THITH_12390 9d25fac97f0e8d9358263bcd0070a96f 1087 Gene3D G3DSA:3.30.450.20 527 643 3.0E-8 T 13-10-2018 THITH_12390 9d25fac97f0e8d9358263bcd0070a96f 1087 SMART SM00052 829 1075 5.0E-122 T 13-10-2018 IPR001633 EAL domain THITH_12390 9d25fac97f0e8d9358263bcd0070a96f 1087 Pfam PF00563 EAL domain 837 1070 7.6E-77 T 13-10-2018 IPR001633 EAL domain THITH_12390 9d25fac97f0e8d9358263bcd0070a96f 1087 Gene3D G3DSA:3.30.450.350 255 467 5.1E-17 T 13-10-2018 THITH_14960 5b3d02783edc321e2365bf7e2de836c3 191 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 183 2.7E-44 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THITH_14960 5b3d02783edc321e2365bf7e2de836c3 191 SMART SM00855 2 148 1.1E-10 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THITH_14960 5b3d02783edc321e2365bf7e2de836c3 191 Gene3D G3DSA:3.40.50.1240 1 186 2.7E-46 T 13-10-2018 IPR029033 Histidine phosphatase superfamily THITH_14960 5b3d02783edc321e2365bf7e2de836c3 191 PIRSF PIRSF000709 28 173 3.2E-7 T 13-10-2018 THITH_14960 5b3d02783edc321e2365bf7e2de836c3 191 SUPERFAMILY SSF53254 1 182 1.46E-45 T 13-10-2018 IPR029033 Histidine phosphatase superfamily THITH_17305 dcd9e74b9709a837d9e82c3d7356528e 158 Gene3D G3DSA:3.40.630.30 3 157 1.1E-20 T 13-10-2018 THITH_17305 dcd9e74b9709a837d9e82c3d7356528e 158 Pfam PF13673 Acetyltransferase (GNAT) domain 86 140 8.2E-10 T 13-10-2018 IPR000182 GNAT domain THITH_17305 dcd9e74b9709a837d9e82c3d7356528e 158 SUPERFAMILY SSF55729 3 144 9.94E-18 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_12280 faa50667823fda4dadeeb6786c38b5e3 157 Pfam PF00877 NlpC/P60 family 55 152 4.6E-24 T 13-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain THITH_12280 faa50667823fda4dadeeb6786c38b5e3 157 Gene3D G3DSA:3.90.1720.10 17 152 2.3E-36 T 13-10-2018 THITH_12280 faa50667823fda4dadeeb6786c38b5e3 157 SUPERFAMILY SSF54001 37 155 8.34E-34 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily THITH_02445 9a1a6d9d738ab831a52c3ccd23a82ee6 355 Gene3D G3DSA:3.40.50.2000 169 354 1.2E-42 T 13-10-2018 THITH_02445 9a1a6d9d738ab831a52c3ccd23a82ee6 355 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 90 308 2.9E-48 T 13-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 THITH_02445 9a1a6d9d738ab831a52c3ccd23a82ee6 355 Gene3D G3DSA:3.40.50.2000 15 160 1.4E-17 T 13-10-2018 THITH_02445 9a1a6d9d738ab831a52c3ccd23a82ee6 355 SUPERFAMILY SSF53756 16 353 7.22E-73 T 13-10-2018 THITH_17325 0ac183acefc10d0f0cc330b8c8fb63e3 421 SUPERFAMILY SSF53784 3 412 3.79E-104 T 13-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THITH_17325 0ac183acefc10d0f0cc330b8c8fb63e3 421 Gene3D G3DSA:3.40.50.450 4 399 1.2E-142 T 13-10-2018 THITH_17325 0ac183acefc10d0f0cc330b8c8fb63e3 421 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 136 153 1.1E-14 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THITH_17325 0ac183acefc10d0f0cc330b8c8fb63e3 421 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 103 119 1.1E-14 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THITH_17325 0ac183acefc10d0f0cc330b8c8fb63e3 421 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 236 248 1.1E-14 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THITH_17325 0ac183acefc10d0f0cc330b8c8fb63e3 421 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 7 26 1.1E-14 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THITH_17325 0ac183acefc10d0f0cc330b8c8fb63e3 421 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 178 194 1.1E-14 T 13-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THITH_17325 0ac183acefc10d0f0cc330b8c8fb63e3 421 Pfam PF00365 Phosphofructokinase 9 322 4.0E-46 T 13-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 THITH_17325 0ac183acefc10d0f0cc330b8c8fb63e3 421 Hamap MF_01978 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 2 398 42.541 T 13-10-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00010+2.7.1.90|KEGG: 00030+2.7.1.90|KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 THITH_17325 0ac183acefc10d0f0cc330b8c8fb63e3 421 PIRSF PIRSF036483 1 417 6.3E-167 T 13-10-2018 IPR011404 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase, XF0274 GO:0006096|GO:0047334 KEGG: 00010+2.7.1.90|KEGG: 00030+2.7.1.90|KEGG: 00051+2.7.1.90|MetaCyc: PWY-1042 THITH_17325 0ac183acefc10d0f0cc330b8c8fb63e3 421 Gene3D G3DSA:3.40.50.460 141 386 1.2E-142 T 13-10-2018 THITH_10340 c4e918b50c35ab1b19ec38ed0e5cc61f 175 Gene3D G3DSA:1.20.120.1200 1 156 6.2E-26 T 13-10-2018 THITH_10340 c4e918b50c35ab1b19ec38ed0e5cc61f 175 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 13 152 6.6E-22 T 13-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 SMART SM00836 465 586 2.2E-51 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 Gene3D G3DSA:1.10.730.10 460 586 1.4E-31 T 13-10-2018 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 PRINTS PR01038 Arginyl-tRNA synthetase signature 334 355 3.4E-21 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 PRINTS PR01038 Arginyl-tRNA synthetase signature 159 172 3.4E-21 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 PRINTS PR01038 Arginyl-tRNA synthetase signature 120 135 3.4E-21 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 PRINTS PR01038 Arginyl-tRNA synthetase signature 135 151 3.4E-21 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 130 139 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 9 586 8.2E-129 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 SMART SM01016 3 91 6.7E-37 T 13-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 SUPERFAMILY SSF52374 113 476 3.85E-90 T 13-10-2018 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 SUPERFAMILY SSF47323 459 586 4.32E-33 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 Hamap MF_00123 Arginine--tRNA ligase [argS]. 3 586 26.532 T 13-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 SUPERFAMILY SSF55190 7 111 3.01E-21 T 13-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 Pfam PF00750 tRNA synthetases class I (R) 299 432 1.8E-12 T 13-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 Pfam PF00750 tRNA synthetases class I (R) 113 179 1.0E-10 T 13-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 Gene3D G3DSA:3.30.1360.70 2 107 2.3E-24 T 13-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 7 91 2.4E-23 T 13-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THITH_01980 5ab444f8a412722eb8a82b2f0ac13786 586 Pfam PF05746 DALR anticodon binding domain 465 586 1.9E-34 T 13-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 THITH_10770 9e09ce646674817d73121d46ecc35867 281 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 9 244 4.5E-65 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_10770 9e09ce646674817d73121d46ecc35867 281 PIRSF PIRSF001430 6 258 1.8E-71 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_10770 9e09ce646674817d73121d46ecc35867 281 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 7 249 34.261 T 13-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_10770 9e09ce646674817d73121d46ecc35867 281 Pfam PF01416 tRNA pseudouridine synthase 14 108 1.9E-6 T 13-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_10770 9e09ce646674817d73121d46ecc35867 281 Pfam PF01416 tRNA pseudouridine synthase 148 250 7.9E-30 T 13-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_10770 9e09ce646674817d73121d46ecc35867 281 Gene3D G3DSA:3.30.70.660 111 248 2.5E-48 T 13-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 THITH_10770 9e09ce646674817d73121d46ecc35867 281 Gene3D G3DSA:3.30.70.580 5 110 4.3E-36 T 13-10-2018 THITH_10770 9e09ce646674817d73121d46ecc35867 281 SUPERFAMILY SSF55120 7 256 2.3E-87 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_05315 73afc5f8c76a3f8ec97a6fa5c4a33e16 454 Gene3D G3DSA:3.10.580.10 130 257 1.1E-30 T 13-10-2018 THITH_05315 73afc5f8c76a3f8ec97a6fa5c4a33e16 454 SUPERFAMILY SSF161093 281 447 1.96E-46 T 13-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 THITH_05315 73afc5f8c76a3f8ec97a6fa5c4a33e16 454 SMART SM00924 31 134 1.8E-22 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain THITH_05315 73afc5f8c76a3f8ec97a6fa5c4a33e16 454 SUPERFAMILY SSF54631 133 267 1.14E-24 T 13-10-2018 THITH_05315 73afc5f8c76a3f8ec97a6fa5c4a33e16 454 SUPERFAMILY SSF158791 6 131 2.49E-23 T 13-10-2018 THITH_05315 73afc5f8c76a3f8ec97a6fa5c4a33e16 454 SMART SM00116 205 253 0.002 T 13-10-2018 IPR000644 CBS domain THITH_05315 73afc5f8c76a3f8ec97a6fa5c4a33e16 454 Pfam PF00571 CBS domain 205 252 4.0E-5 T 13-10-2018 IPR000644 CBS domain THITH_05315 73afc5f8c76a3f8ec97a6fa5c4a33e16 454 Pfam PF00571 CBS domain 134 190 3.6E-6 T 13-10-2018 IPR000644 CBS domain THITH_05315 73afc5f8c76a3f8ec97a6fa5c4a33e16 454 TIGRFAM TIGR00400 mgtE: magnesium transporter 5 448 1.7E-98 T 13-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 THITH_05315 73afc5f8c76a3f8ec97a6fa5c4a33e16 454 Gene3D G3DSA:1.25.60.10 2 127 3.3E-19 T 13-10-2018 IPR038076 MgtE, N-terminal domain superfamily THITH_05315 73afc5f8c76a3f8ec97a6fa5c4a33e16 454 Pfam PF01769 Divalent cation transporter 321 440 1.2E-26 T 13-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 THITH_05315 73afc5f8c76a3f8ec97a6fa5c4a33e16 454 Gene3D G3DSA:1.10.357.20 273 447 2.4E-51 T 13-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain THITH_05315 73afc5f8c76a3f8ec97a6fa5c4a33e16 454 Pfam PF03448 MgtE intracellular N domain 31 132 8.8E-18 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain THITH_10205 3b62404c0a8a3ae1e61abb706344983d 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 373 387 6.3E-18 T 13-10-2018 IPR003004 GspF/PilC family THITH_10205 3b62404c0a8a3ae1e61abb706344983d 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 71 83 6.3E-18 T 13-10-2018 IPR003004 GspF/PilC family THITH_10205 3b62404c0a8a3ae1e61abb706344983d 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 389 408 6.3E-18 T 13-10-2018 IPR003004 GspF/PilC family THITH_10205 3b62404c0a8a3ae1e61abb706344983d 409 PRINTS PR00812 Bacterial general secretion pathway protein F signature 170 198 6.3E-18 T 13-10-2018 IPR003004 GspF/PilC family THITH_10205 3b62404c0a8a3ae1e61abb706344983d 409 Gene3D G3DSA:1.20.81.30 261 373 4.5E-28 T 13-10-2018 THITH_10205 3b62404c0a8a3ae1e61abb706344983d 409 Pfam PF00482 Type II secretion system (T2SS), protein F 278 399 1.6E-27 T 13-10-2018 IPR018076 Type II secretion system F domain THITH_10205 3b62404c0a8a3ae1e61abb706344983d 409 Pfam PF00482 Type II secretion system (T2SS), protein F 75 198 1.3E-28 T 13-10-2018 IPR018076 Type II secretion system F domain THITH_10205 3b62404c0a8a3ae1e61abb706344983d 409 Gene3D G3DSA:1.20.81.30 62 177 1.5E-25 T 13-10-2018 THITH_11165 1204d7bfc78716905fb2c4f836e2458c 203 Pfam PF01609 Transposase DDE domain 28 177 3.4E-6 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 SUPERFAMILY SSF82693 557 659 4.18E-13 T 13-10-2018 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 SUPERFAMILY SSF82714 183 265 5.23E-18 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 Gene3D G3DSA:3.30.70.1430 40 805 1.2E-287 T 13-10-2018 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 Gene3D G3DSA:3.30.70.1320 134 326 1.2E-287 T 13-10-2018 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 Gene3D G3DSA:3.30.2090.10 178 268 1.2E-287 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 SUPERFAMILY SSF82714 710 795 9.94E-16 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 Gene3D G3DSA:1.20.1640.10 10 504 1.2E-287 T 13-10-2018 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 Pfam PF00873 AcrB/AcrD/AcrF family 4 1014 1.9E-260 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 SUPERFAMILY SSF82693 41 128 5.23E-20 T 13-10-2018 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 SUPERFAMILY SSF82866 798 1016 4.05E-47 T 13-10-2018 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 Gene3D G3DSA:3.30.70.1430 559 657 1.2E-287 T 13-10-2018 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 Gene3D G3DSA:1.20.1640.10 505 1011 1.2E-287 T 13-10-2018 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 Gene3D G3DSA:3.30.2090.10 709 797 1.2E-287 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 PRINTS PR00702 Acriflavin resistance protein family signature 357 378 3.4E-70 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 3.4E-70 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 PRINTS PR00702 Acriflavin resistance protein family signature 612 626 3.4E-70 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 PRINTS PR00702 Acriflavin resistance protein family signature 385 409 3.4E-70 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 PRINTS PR00702 Acriflavin resistance protein family signature 544 561 3.4E-70 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 PRINTS PR00702 Acriflavin resistance protein family signature 463 486 3.4E-70 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 PRINTS PR00702 Acriflavin resistance protein family signature 330 353 3.4E-70 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 PRINTS PR00702 Acriflavin resistance protein family signature 438 461 3.4E-70 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 3.4E-70 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 SUPERFAMILY SSF82693 138 324 1.05E-19 T 13-10-2018 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 Gene3D G3DSA:3.30.70.1440 658 854 1.2E-287 T 13-10-2018 THITH_10855 4d87870d72593cbf5464c5c79f0c0014 1032 SUPERFAMILY SSF82866 289 490 2.62E-51 T 13-10-2018 THITH_12335 911a4c8f442ee5b7c7a9f568e8724b31 102 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 26 45 - T 13-10-2018 IPR020808 Bacterial microcompartments protein, conserved site THITH_12335 911a4c8f442ee5b7c7a9f568e8724b31 102 Gene3D G3DSA:3.30.70.1710 2 102 2.3E-36 T 13-10-2018 THITH_12335 911a4c8f442ee5b7c7a9f568e8724b31 102 SUPERFAMILY SSF143414 9 95 2.49E-28 T 13-10-2018 IPR037233 CcmK-like superfamily THITH_12335 911a4c8f442ee5b7c7a9f568e8724b31 102 SMART SM00877 8 85 8.5E-31 T 13-10-2018 IPR000249 Microcompartment protein, bacteria THITH_12335 911a4c8f442ee5b7c7a9f568e8724b31 102 Pfam PF00936 BMC domain 9 85 8.2E-26 T 13-10-2018 IPR000249 Microcompartment protein, bacteria THITH_12335 911a4c8f442ee5b7c7a9f568e8724b31 102 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 9 70 2.0E-19 T 13-10-2018 THITH_14765 cb2af9dc29c4e2cee730b1fd0e87c019 363 Gene3D G3DSA:3.40.50.300 3 278 2.7E-154 T 13-10-2018 THITH_14765 cb2af9dc29c4e2cee730b1fd0e87c019 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 3.8E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_14765 cb2af9dc29c4e2cee730b1fd0e87c019 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 3.8E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_14765 cb2af9dc29c4e2cee730b1fd0e87c019 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 3.8E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_14765 cb2af9dc29c4e2cee730b1fd0e87c019 363 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 3.8E-34 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_14765 cb2af9dc29c4e2cee730b1fd0e87c019 363 Pfam PF01926 50S ribosome-binding GTPase 5 124 1.9E-22 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_14765 cb2af9dc29c4e2cee730b1fd0e87c019 363 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 363 9.1E-156 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 THITH_14765 cb2af9dc29c4e2cee730b1fd0e87c019 363 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 363 44.945 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 THITH_14765 cb2af9dc29c4e2cee730b1fd0e87c019 363 SUPERFAMILY SSF52540 3 301 1.06E-82 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14765 cb2af9dc29c4e2cee730b1fd0e87c019 363 Gene3D G3DSA:1.10.150.300 113 200 2.7E-154 T 13-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 THITH_14765 cb2af9dc29c4e2cee730b1fd0e87c019 363 Pfam PF06071 Protein of unknown function (DUF933) 279 362 5.3E-41 T 13-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 THITH_14765 cb2af9dc29c4e2cee730b1fd0e87c019 363 SUPERFAMILY SSF81271 279 360 3.92E-37 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 THITH_14765 cb2af9dc29c4e2cee730b1fd0e87c019 363 Gene3D G3DSA:3.10.20.30 48 361 2.7E-154 T 13-10-2018 IPR012675 Beta-grasp domain superfamily THITH_14765 cb2af9dc29c4e2cee730b1fd0e87c019 363 PIRSF PIRSF006641 1 363 1.5E-153 T 13-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 THITH_16365 ffffcd31b19623b30ee0e433a7aec36e 406 Gene3D G3DSA:3.40.50.10380 1 160 3.2E-67 T 13-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 THITH_16365 ffffcd31b19623b30ee0e433a7aec36e 406 Gene3D G3DSA:3.40.50.720 161 406 1.6E-84 T 13-10-2018 THITH_16365 ffffcd31b19623b30ee0e433a7aec36e 406 SUPERFAMILY SSF51735 163 405 8.12E-83 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_16365 ffffcd31b19623b30ee0e433a7aec36e 406 PIRSF PIRSF000106 50 406 7.0E-72 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 THITH_16365 ffffcd31b19623b30ee0e433a7aec36e 406 SMART SM01274 18 151 3.0E-75 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 THITH_16365 ffffcd31b19623b30ee0e433a7aec36e 406 Pfam PF00390 Malic enzyme, N-terminal domain 20 150 2.6E-25 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 THITH_16365 ffffcd31b19623b30ee0e433a7aec36e 406 ProSitePatterns PS00331 Malic enzymes signature. 159 175 - T 13-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 THITH_16365 ffffcd31b19623b30ee0e433a7aec36e 406 SUPERFAMILY SSF53223 10 161 3.81E-51 T 13-10-2018 THITH_16365 ffffcd31b19623b30ee0e433a7aec36e 406 Pfam PF03949 Malic enzyme, NAD binding domain 165 356 1.1E-29 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 THITH_16365 ffffcd31b19623b30ee0e433a7aec36e 406 SMART SM00919 163 399 5.9E-143 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 THITH_08175 fc4fdb860096f76dceea2315b3b9e0a9 646 SUPERFAMILY SSF55874 512 616 6.55E-16 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_08175 fc4fdb860096f76dceea2315b3b9e0a9 646 Pfam PF07730 Histidine kinase 419 484 4.7E-17 T 13-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 THITH_08175 fc4fdb860096f76dceea2315b3b9e0a9 646 SUPERFAMILY SSF55781 284 415 7.41E-10 T 13-10-2018 THITH_08175 fc4fdb860096f76dceea2315b3b9e0a9 646 PIRSF PIRSF003167 2 628 1.0E-179 T 13-10-2018 IPR016380 Signal transduction histidine kinase, nitrate/nitrite-sensing GO:0000155|GO:0000160|GO:0004673|GO:0016021 THITH_08175 fc4fdb860096f76dceea2315b3b9e0a9 646 SMART SM00304 193 245 2.2E-10 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_08175 fc4fdb860096f76dceea2315b3b9e0a9 646 Pfam PF00672 HAMP domain 195 241 4.6E-9 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_08175 fc4fdb860096f76dceea2315b3b9e0a9 646 Pfam PF13675 Type IV pili methyl-accepting chemotaxis transducer N-term 36 137 3.5E-10 T 13-10-2018 IPR029095 NarX-like, N-terminal THITH_08175 fc4fdb860096f76dceea2315b3b9e0a9 646 SUPERFAMILY SSF158472 195 243 1.57E-8 T 13-10-2018 THITH_08175 fc4fdb860096f76dceea2315b3b9e0a9 646 Gene3D G3DSA:1.20.120.960 40 165 6.4E-12 T 13-10-2018 THITH_08175 fc4fdb860096f76dceea2315b3b9e0a9 646 Gene3D G3DSA:1.10.287.130 191 283 5.2E-7 T 13-10-2018 THITH_08175 fc4fdb860096f76dceea2315b3b9e0a9 646 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 526 613 1.5E-7 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_08175 fc4fdb860096f76dceea2315b3b9e0a9 646 SMART SM00387 525 619 4.0E-11 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_08175 fc4fdb860096f76dceea2315b3b9e0a9 646 Gene3D G3DSA:3.30.565.10 485 618 2.0E-25 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_08175 fc4fdb860096f76dceea2315b3b9e0a9 646 Gene3D G3DSA:3.30.450.40 284 419 4.9E-6 T 13-10-2018 IPR029016 GAF-like domain superfamily THITH_12715 3e1aba49222ff5a8e42aace2c3c69d45 146 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 50 86 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 THITH_12715 3e1aba49222ff5a8e42aace2c3c69d45 146 SUPERFAMILY SSF53927 2 143 2.01E-41 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 THITH_12715 3e1aba49222ff5a8e42aace2c3c69d45 146 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 97 1.5E-24 T 13-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain THITH_12715 3e1aba49222ff5a8e42aace2c3c69d45 146 Gene3D G3DSA:3.40.140.10 1 145 6.4E-46 T 13-10-2018 THITH_14480 9aafbade94dd1bd47d73cd36c33c73bb 361 ProSitePatterns PS01347 MraY family signature 1. 68 80 - T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_14480 9aafbade94dd1bd47d73cd36c33c73bb 361 ProSitePatterns PS01348 MraY family signature 2. 190 201 - T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_14480 9aafbade94dd1bd47d73cd36c33c73bb 361 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 68 80 3.3E-5 T 13-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_14480 9aafbade94dd1bd47d73cd36c33c73bb 361 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 25 359 24.427 T 13-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_14480 9aafbade94dd1bd47d73cd36c33c73bb 361 Pfam PF00953 Glycosyl transferase family 4 99 285 7.5E-39 T 13-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 THITH_14480 9aafbade94dd1bd47d73cd36c33c73bb 361 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 38 361 1.3E-128 T 13-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_10125 6504bb86549919e53355dab45617db69 338 Pfam PF00953 Glycosyl transferase family 4 76 227 1.2E-26 T 13-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 THITH_04475 b8a48d4f6133a6ca9e6c3656a22045e0 336 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 247 312 4.2E-17 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THITH_04475 b8a48d4f6133a6ca9e6c3656a22045e0 336 Pfam PF00005 ABC transporter 43 195 1.2E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_04475 b8a48d4f6133a6ca9e6c3656a22045e0 336 Gene3D G3DSA:3.40.50.300 15 336 1.5E-93 T 13-10-2018 THITH_04475 b8a48d4f6133a6ca9e6c3656a22045e0 336 SUPERFAMILY SSF52540 17 267 6.55E-67 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_04475 b8a48d4f6133a6ca9e6c3656a22045e0 336 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 245 334 5.7E-22 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THITH_04475 b8a48d4f6133a6ca9e6c3656a22045e0 336 SMART SM00382 51 245 4.4E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_04475 b8a48d4f6133a6ca9e6c3656a22045e0 336 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_04965 ed2ada9f016dbeb0ed9785df6fa1b4b0 310 SUPERFAMILY SSF56601 13 277 8.02E-53 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like THITH_04965 ed2ada9f016dbeb0ed9785df6fa1b4b0 310 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 36 260 8.0E-52 T 13-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 THITH_04965 ed2ada9f016dbeb0ed9785df6fa1b4b0 310 Gene3D G3DSA:3.40.710.10 22 298 1.9E-60 T 13-10-2018 THITH_04965 ed2ada9f016dbeb0ed9785df6fa1b4b0 310 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 67 78 1.3E-12 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THITH_04965 ed2ada9f016dbeb0ed9785df6fa1b4b0 310 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 117 134 1.3E-12 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THITH_04965 ed2ada9f016dbeb0ed9785df6fa1b4b0 310 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 144 157 1.3E-12 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THITH_14005 529a996ff9a68a0bc103edc7f1ede416 386 Pfam PF00549 CoA-ligase 262 381 3.1E-25 T 13-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THITH_14005 529a996ff9a68a0bc103edc7f1ede416 386 PIRSF PIRSF001554 1 386 8.1E-140 T 13-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THITH_14005 529a996ff9a68a0bc103edc7f1ede416 386 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 281 - T 13-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THITH_14005 529a996ff9a68a0bc103edc7f1ede416 386 SUPERFAMILY SSF52210 240 384 3.27E-51 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THITH_14005 529a996ff9a68a0bc103edc7f1ede416 386 Gene3D G3DSA:3.30.1490.20 21 104 1.6E-80 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 THITH_14005 529a996ff9a68a0bc103edc7f1ede416 386 Gene3D G3DSA:3.30.470.20 1 234 1.6E-80 T 13-10-2018 THITH_14005 529a996ff9a68a0bc103edc7f1ede416 386 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 7.7E-147 T 13-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THITH_14005 529a996ff9a68a0bc103edc7f1ede416 386 Gene3D G3DSA:3.40.50.261 240 386 5.0E-56 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THITH_14005 529a996ff9a68a0bc103edc7f1ede416 386 Pfam PF08442 ATP-grasp domain 2 202 1.4E-61 T 13-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THITH_14005 529a996ff9a68a0bc103edc7f1ede416 386 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 40.4 T 13-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THITH_14005 529a996ff9a68a0bc103edc7f1ede416 386 SUPERFAMILY SSF56059 1 237 1.3E-67 T 13-10-2018 THITH_05415 ed5374930ae6f3e7a25bdc029630cd4b 378 Gene3D G3DSA:1.10.3210.10 147 363 1.4E-76 T 13-10-2018 THITH_05415 ed5374930ae6f3e7a25bdc029630cd4b 378 SUPERFAMILY SSF109604 148 348 1.26E-34 T 13-10-2018 THITH_05415 ed5374930ae6f3e7a25bdc029630cd4b 378 SMART SM00448 7 120 2.3E-35 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_05415 ed5374930ae6f3e7a25bdc029630cd4b 378 SMART SM00471 169 320 2.4E-7 T 13-10-2018 IPR003607 HD/PDEase domain THITH_05415 ed5374930ae6f3e7a25bdc029630cd4b 378 Pfam PF13487 HD domain 232 302 1.2E-18 T 13-10-2018 THITH_05415 ed5374930ae6f3e7a25bdc029630cd4b 378 Pfam PF00072 Response regulator receiver domain 9 120 1.3E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_05415 ed5374930ae6f3e7a25bdc029630cd4b 378 SUPERFAMILY SSF52172 6 157 1.99E-38 T 13-10-2018 IPR011006 CheY-like superfamily THITH_05415 ed5374930ae6f3e7a25bdc029630cd4b 378 Gene3D G3DSA:3.40.50.2300 1 137 1.2E-37 T 13-10-2018 THITH_04930 adcc2cccb7809d554e510bd292dbc803 247 Gene3D G3DSA:3.40.630.70 63 239 2.4E-65 T 13-10-2018 THITH_04930 adcc2cccb7809d554e510bd292dbc803 247 Gene3D G3DSA:2.30.210.20 7 62 1.7E-22 T 13-10-2018 THITH_04930 adcc2cccb7809d554e510bd292dbc803 247 SUPERFAMILY SSF55729 10 230 1.06E-89 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_04930 adcc2cccb7809d554e510bd292dbc803 247 Pfam PF03588 Leucyl/phenylalanyl-tRNA protein transferase 37 206 7.6E-72 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 THITH_04930 adcc2cccb7809d554e510bd292dbc803 247 TIGRFAM TIGR00667 aat: leucyl/phenylalanyl-tRNA--protein transferase 40 219 5.6E-60 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 THITH_04930 adcc2cccb7809d554e510bd292dbc803 247 Hamap MF_00688 Leucyl/phenylalanyl-tRNA--protein transferase [aat]. 1 247 97.607 T 13-10-2018 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase GO:0008914|GO:0030163 MetaCyc: PWY-7801 THITH_10780 aeb1c5a76b609079d4e90843734a0528 791 TIGRFAM TIGR03505 FimV_core: FimV N-terminal domain 160 232 3.6E-19 T 13-10-2018 IPR020012 Motility protein FimV, N-terminal THITH_10780 aeb1c5a76b609079d4e90843734a0528 791 TIGRFAM TIGR03504 FimV_Cterm: FimV C-terminal domain 743 785 1.4E-8 T 13-10-2018 IPR020011 Motility protein FimV, C-terminal THITH_10780 aeb1c5a76b609079d4e90843734a0528 791 Gene3D G3DSA:1.20.58.2200 723 785 1.4E-10 T 13-10-2018 IPR038440 FimV, C-terminal domain superfamily THITH_03555 020dcb4a8db0fb3ff8637a1e9e59bd26 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 1.0E-21 T 13-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03555 020dcb4a8db0fb3ff8637a1e9e59bd26 149 SUPERFAMILY SSF55658 1 56 1.92E-18 T 13-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal THITH_03555 020dcb4a8db0fb3ff8637a1e9e59bd26 149 Gene3D G3DSA:3.10.430.100 61 148 1.9E-27 T 13-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily THITH_03555 020dcb4a8db0fb3ff8637a1e9e59bd26 149 Gene3D G3DSA:3.40.5.10 1 50 1.2E-22 T 13-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03555 020dcb4a8db0fb3ff8637a1e9e59bd26 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 25.799 T 13-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_03555 020dcb4a8db0fb3ff8637a1e9e59bd26 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 13-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03555 020dcb4a8db0fb3ff8637a1e9e59bd26 149 SUPERFAMILY SSF55653 60 147 6.15E-25 T 13-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily THITH_03555 020dcb4a8db0fb3ff8637a1e9e59bd26 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 145 1.7E-47 T 13-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_03555 020dcb4a8db0fb3ff8637a1e9e59bd26 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 146 8.0E-25 T 13-10-2018 IPR020069 Ribosomal protein L9, C-terminal THITH_10795 3d8450199ba3ef07dda6625ac7ebc928 213 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 210 43.792 T 13-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 THITH_10795 3d8450199ba3ef07dda6625ac7ebc928 213 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 196 4.4E-81 T 13-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 THITH_10795 3d8450199ba3ef07dda6625ac7ebc928 213 Pfam PF00694 Aconitase C-terminal domain 1 132 3.1E-34 T 13-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 THITH_10795 3d8450199ba3ef07dda6625ac7ebc928 213 Gene3D G3DSA:3.20.19.10 1 188 4.2E-76 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 THITH_10795 3d8450199ba3ef07dda6625ac7ebc928 213 SUPERFAMILY SSF52016 1 205 7.26E-61 T 13-10-2018 THITH_09675 1c6cf0296c49a67e18ec56a0af245ba9 301 Gene3D G3DSA:3.30.70.1290 1 157 1.7E-24 T 13-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 THITH_09675 1c6cf0296c49a67e18ec56a0af245ba9 301 Pfam PF13384 Homeodomain-like domain 240 277 1.7E-7 T 13-10-2018 THITH_09675 1c6cf0296c49a67e18ec56a0af245ba9 301 Pfam PF01797 Transposase IS200 like 13 105 8.3E-6 T 13-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THITH_09675 1c6cf0296c49a67e18ec56a0af245ba9 301 SMART SM01321 9 115 2.9E-16 T 13-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THITH_09675 1c6cf0296c49a67e18ec56a0af245ba9 301 SUPERFAMILY SSF143422 3 115 8.5E-14 T 13-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 THITH_05385 cc08099d535bb511614c4f916ea131dd 444 Pfam PF13379 NMT1-like family 44 303 1.7E-99 T 13-10-2018 THITH_05385 cc08099d535bb511614c4f916ea131dd 444 Gene3D G3DSA:3.40.190.10 144 422 1.4E-129 T 13-10-2018 THITH_05385 cc08099d535bb511614c4f916ea131dd 444 Gene3D G3DSA:3.40.190.10 51 417 1.4E-129 T 13-10-2018 THITH_05385 cc08099d535bb511614c4f916ea131dd 444 SUPERFAMILY SSF53850 51 298 5.61E-20 T 13-10-2018 THITH_16605 cdee4791f529df5bc2ad7b9b87bde126 246 SMART SM00418 39 118 1.4E-24 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THITH_16605 cdee4791f529df5bc2ad7b9b87bde126 246 SMART SM00450 144 240 7.2E-21 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_16605 cdee4791f529df5bc2ad7b9b87bde126 246 Gene3D G3DSA:3.40.250.10 140 245 1.5E-26 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_16605 cdee4791f529df5bc2ad7b9b87bde126 246 SUPERFAMILY SSF52821 133 243 4.14E-29 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_16605 cdee4791f529df5bc2ad7b9b87bde126 246 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 41 56 1.6E-10 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THITH_16605 cdee4791f529df5bc2ad7b9b87bde126 246 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 73 88 1.6E-10 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THITH_16605 cdee4791f529df5bc2ad7b9b87bde126 246 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 88 103 1.6E-10 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THITH_16605 cdee4791f529df5bc2ad7b9b87bde126 246 Pfam PF12840 Helix-turn-helix domain 38 96 1.4E-13 T 13-10-2018 THITH_16605 cdee4791f529df5bc2ad7b9b87bde126 246 Gene3D G3DSA:1.10.10.10 24 130 2.3E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_16605 cdee4791f529df5bc2ad7b9b87bde126 246 Pfam PF00581 Rhodanese-like domain 146 237 5.5E-13 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_16605 cdee4791f529df5bc2ad7b9b87bde126 246 SUPERFAMILY SSF46785 33 153 2.68E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_11260 45b17fea85fd74b3effb92fbe5ef8593 739 Gene3D G3DSA:2.60.40.10 40 176 2.3E-46 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_11260 45b17fea85fd74b3effb92fbe5ef8593 739 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 48 135 1.3E-18 T 13-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 THITH_11260 45b17fea85fd74b3effb92fbe5ef8593 739 Gene3D G3DSA:3.20.20.80 177 620 1.5E-185 T 13-10-2018 THITH_11260 45b17fea85fd74b3effb92fbe5ef8593 739 Pfam PF00128 Alpha amylase, catalytic domain 228 571 9.9E-13 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THITH_11260 45b17fea85fd74b3effb92fbe5ef8593 739 Gene3D G3DSA:2.60.40.1180 626 736 4.2E-17 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta THITH_11260 45b17fea85fd74b3effb92fbe5ef8593 739 SUPERFAMILY SSF51011 627 736 1.65E-24 T 13-10-2018 THITH_11260 45b17fea85fd74b3effb92fbe5ef8593 739 SUPERFAMILY SSF81296 43 187 5.88E-47 T 13-10-2018 IPR014756 Immunoglobulin E-set THITH_11260 45b17fea85fd74b3effb92fbe5ef8593 739 SUPERFAMILY SSF51445 173 614 1.06E-135 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily THITH_11260 45b17fea85fd74b3effb92fbe5ef8593 739 SMART SM00642 198 606 2.0E-9 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THITH_11260 45b17fea85fd74b3effb92fbe5ef8593 739 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 44 736 0.0 T 13-10-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 THITH_07805 c473844b689eee36b6d8bd5ed5ffb2e1 374 PIRSF PIRSF000390 1 374 5.8E-104 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THITH_07805 c473844b689eee36b6d8bd5ed5ffb2e1 374 SUPERFAMILY SSF53383 7 370 1.06E-95 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_07805 c473844b689eee36b6d8bd5ed5ffb2e1 374 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 18 367 2.9E-100 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THITH_07805 c473844b689eee36b6d8bd5ed5ffb2e1 374 Gene3D G3DSA:3.40.640.10 5 373 9.3E-104 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_07940 1e850837676aa83950e5f1f59a5c6abf 387 Gene3D G3DSA:3.30.70.260 308 387 3.6E-15 T 13-10-2018 THITH_07940 1e850837676aa83950e5f1f59a5c6abf 387 SUPERFAMILY SSF51735 83 274 4.25E-41 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_07940 1e850837676aa83950e5f1f59a5c6abf 387 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 23 306 2.0E-16 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 THITH_07940 1e850837676aa83950e5f1f59a5c6abf 387 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 191 213 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site THITH_07940 1e850837676aa83950e5f1f59a5c6abf 387 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 140 167 - T 13-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 THITH_07940 1e850837676aa83950e5f1f59a5c6abf 387 Gene3D G3DSA:3.40.50.720 24 297 2.5E-67 T 13-10-2018 THITH_07940 1e850837676aa83950e5f1f59a5c6abf 387 SUPERFAMILY SSF55021 314 387 5.04E-9 T 13-10-2018 THITH_07940 1e850837676aa83950e5f1f59a5c6abf 387 Gene3D G3DSA:3.40.50.720 83 272 2.5E-67 T 13-10-2018 THITH_07940 1e850837676aa83950e5f1f59a5c6abf 387 SUPERFAMILY SSF52283 7 105 4.35E-16 T 13-10-2018 THITH_07940 1e850837676aa83950e5f1f59a5c6abf 387 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 119 274 1.2E-39 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 THITH_14775 c481f33834850251e34830ed192ab6a0 212 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 7 97 2.0E-19 T 13-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 THITH_14775 c481f33834850251e34830ed192ab6a0 212 Gene3D G3DSA:2.170.120.20 99 200 5.9E-29 T 13-10-2018 IPR037121 Ribosomal protein L25, C-terminal THITH_14775 c481f33834850251e34830ed192ab6a0 212 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 8 175 1.8E-43 T 13-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 THITH_14775 c481f33834850251e34830ed192ab6a0 212 Hamap MF_01336 50S ribosomal protein L25 [rplY]. 5 97 24.53 T 13-10-2018 IPR020055 Ribosomal protein L25, short-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 THITH_14775 c481f33834850251e34830ed192ab6a0 212 SUPERFAMILY SSF50715 5 198 4.53E-57 T 13-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THITH_14775 c481f33834850251e34830ed192ab6a0 212 Pfam PF01386 Ribosomal L25p family 7 94 1.1E-24 T 13-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 THITH_14775 c481f33834850251e34830ed192ab6a0 212 Gene3D G3DSA:2.40.240.10 5 97 1.9E-30 T 13-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THITH_14775 c481f33834850251e34830ed192ab6a0 212 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 103 193 2.1E-30 T 13-10-2018 IPR020057 Ribosomal protein L25, beta domain THITH_14775 c481f33834850251e34830ed192ab6a0 212 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 5 191 31.702 T 13-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 THITH_03720 cc8eccfb08f17644c28a2dd47d63aa6c 93 SUPERFAMILY SSF47413 33 72 9.48E-8 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 THITH_03720 cc8eccfb08f17644c28a2dd47d63aa6c 93 Pfam PF13560 Helix-turn-helix domain 31 73 2.8E-6 T 13-10-2018 THITH_03720 cc8eccfb08f17644c28a2dd47d63aa6c 93 SMART SM00530 33 87 2.7E-5 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_03720 cc8eccfb08f17644c28a2dd47d63aa6c 93 Gene3D G3DSA:1.10.260.40 33 93 1.1E-14 T 13-10-2018 THITH_14580 a134390e3a496fda319f20e140522b59 433 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 233 265 - T 13-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 THITH_14580 a134390e3a496fda319f20e140522b59 433 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 5 432 39.999 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THITH_14580 a134390e3a496fda319f20e140522b59 433 Gene3D G3DSA:3.40.50.1980 237 354 1.6E-127 T 13-10-2018 THITH_14580 a134390e3a496fda319f20e140522b59 433 PRINTS PR00083 Histidinol dehydrogenase signature 324 349 1.1E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THITH_14580 a134390e3a496fda319f20e140522b59 433 PRINTS PR00083 Histidinol dehydrogenase signature 140 166 1.1E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THITH_14580 a134390e3a496fda319f20e140522b59 433 PRINTS PR00083 Histidinol dehydrogenase signature 36 60 1.1E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THITH_14580 a134390e3a496fda319f20e140522b59 433 PRINTS PR00083 Histidinol dehydrogenase signature 174 200 1.1E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THITH_14580 a134390e3a496fda319f20e140522b59 433 PRINTS PR00083 Histidinol dehydrogenase signature 255 274 1.1E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THITH_14580 a134390e3a496fda319f20e140522b59 433 PRINTS PR00083 Histidinol dehydrogenase signature 204 229 1.1E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THITH_14580 a134390e3a496fda319f20e140522b59 433 PRINTS PR00083 Histidinol dehydrogenase signature 233 254 1.1E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THITH_14580 a134390e3a496fda319f20e140522b59 433 PRINTS PR00083 Histidinol dehydrogenase signature 366 384 1.1E-80 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THITH_14580 a134390e3a496fda319f20e140522b59 433 SUPERFAMILY SSF53720 30 431 1.73E-87 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 THITH_14580 a134390e3a496fda319f20e140522b59 433 Pfam PF00815 Histidinol dehydrogenase 28 431 8.7E-165 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THITH_14580 a134390e3a496fda319f20e140522b59 433 PIRSF PIRSF000099 4 433 2.2E-155 T 13-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THITH_14580 a134390e3a496fda319f20e140522b59 433 Gene3D G3DSA:3.40.50.1980 34 235 1.6E-127 T 13-10-2018 THITH_14580 a134390e3a496fda319f20e140522b59 433 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 36 431 1.5E-158 T 13-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 THITH_12900 ac8f3c1cad6f97941584255bb755b1ab 142 ProSitePatterns PS01319 Ribosome-binding factor A signature. 78 99 - T 13-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 THITH_12900 ac8f3c1cad6f97941584255bb755b1ab 142 SUPERFAMILY SSF89919 5 114 7.59E-34 T 13-10-2018 IPR023799 Ribosome-binding factor A domain superfamily THITH_12900 ac8f3c1cad6f97941584255bb755b1ab 142 Pfam PF02033 Ribosome-binding factor A 9 112 1.3E-30 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 THITH_12900 ac8f3c1cad6f97941584255bb755b1ab 142 Gene3D G3DSA:3.30.300.20 4 122 4.5E-34 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta THITH_12900 ac8f3c1cad6f97941584255bb755b1ab 142 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 8 114 5.6E-31 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 THITH_12900 ac8f3c1cad6f97941584255bb755b1ab 142 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 8 112 26.387 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 THITH_12900 ac8f3c1cad6f97941584255bb755b1ab 142 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 12 99 3.0E-26 T 13-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 THITH_10535 5558159f7848a2499253593abfe29f8d 724 Pfam PF13291 ACT domain 641 714 1.9E-16 T 13-10-2018 IPR002912 ACT domain THITH_10535 5558159f7848a2499253593abfe29f8d 724 SUPERFAMILY SSF81301 198 368 3.27E-60 T 13-10-2018 THITH_10535 5558159f7848a2499253593abfe29f8d 724 SUPERFAMILY SSF55021 639 715 7.85E-14 T 13-10-2018 THITH_10535 5558159f7848a2499253593abfe29f8d 724 SUPERFAMILY SSF109604 48 196 8.47E-37 T 13-10-2018 THITH_10535 5558159f7848a2499253593abfe29f8d 724 Gene3D G3DSA:3.30.460.10 199 331 3.6E-49 T 13-10-2018 THITH_10535 5558159f7848a2499253593abfe29f8d 724 Gene3D G3DSA:3.10.20.30 383 454 5.2E-29 T 13-10-2018 IPR012675 Beta-grasp domain superfamily THITH_10535 5558159f7848a2499253593abfe29f8d 724 SMART SM00954 241 351 6.0E-67 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 THITH_10535 5558159f7848a2499253593abfe29f8d 724 Pfam PF02824 TGS domain 390 449 1.2E-19 T 13-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 THITH_10535 5558159f7848a2499253593abfe29f8d 724 Gene3D G3DSA:1.10.3210.10 45 197 4.7E-40 T 13-10-2018 THITH_10535 5558159f7848a2499253593abfe29f8d 724 Pfam PF13328 HD domain 50 181 2.3E-34 T 13-10-2018 IPR003607 HD/PDEase domain THITH_10535 5558159f7848a2499253593abfe29f8d 724 Gene3D G3DSA:3.30.70.260 640 724 7.3E-17 T 13-10-2018 THITH_10535 5558159f7848a2499253593abfe29f8d 724 SUPERFAMILY SSF81271 384 449 1.72E-18 T 13-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 THITH_10535 5558159f7848a2499253593abfe29f8d 724 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 51 713 1.1E-176 T 13-10-2018 IPR004811 RelA/SpoT family GO:0015969 THITH_10535 5558159f7848a2499253593abfe29f8d 724 Pfam PF04607 Region found in RelA / SpoT proteins 241 350 3.2E-38 T 13-10-2018 IPR007685 RelA/SpoT GO:0015969 THITH_05440 43e39c3aff5a9f2d737e019efd88366e 434 Pfam PF03781 Sulfatase-modifying factor enzyme 1 171 429 4.1E-46 T 13-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THITH_05440 43e39c3aff5a9f2d737e019efd88366e 434 SUPERFAMILY SSF56436 171 430 1.68E-69 T 13-10-2018 IPR016187 C-type lectin fold THITH_05440 43e39c3aff5a9f2d737e019efd88366e 434 Gene3D G3DSA:1.20.120.450 3 142 3.6E-9 T 13-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes THITH_05440 43e39c3aff5a9f2d737e019efd88366e 434 Gene3D G3DSA:3.90.1580.10 166 434 1.9E-54 T 13-10-2018 THITH_05440 43e39c3aff5a9f2d737e019efd88366e 434 SUPERFAMILY SSF109854 7 136 1.39E-15 T 13-10-2018 IPR034660 DinB/YfiT-like putative metalloenzymes THITH_05440 43e39c3aff5a9f2d737e019efd88366e 434 TIGRFAM TIGR04373 egtB_X_signatur: EgtB-related enzyme signature domain 382 431 3.8E-27 T 13-10-2018 IPR030809 EgtB-related enzyme signature domain THITH_05440 43e39c3aff5a9f2d737e019efd88366e 434 Pfam PF12867 DinB superfamily 12 135 1.3E-10 T 13-10-2018 IPR024775 DinB-like domain THITH_05440 43e39c3aff5a9f2d737e019efd88366e 434 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 10 430 5.0E-121 T 13-10-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 10 205 1.9E-73 T 13-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 SUPERFAMILY SSF54810 405 525 5.23E-50 T 13-10-2018 THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 Gene3D G3DSA:3.40.50.880 9 206 1.7E-52 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 PRINTS PR00097 Anthranilate synthase component II signature 81 92 2.5E-6 T 13-10-2018 THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 PRINTS PR00097 Anthranilate synthase component II signature 54 63 2.5E-6 T 13-10-2018 THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 PRINTS PR00097 Anthranilate synthase component II signature 177 190 2.5E-6 T 13-10-2018 THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 Pfam PF00117 Glutamine amidotransferase class-I 12 200 2.9E-37 T 13-10-2018 IPR017926 Glutamine amidotransferase THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 7 525 55.626 T 13-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 212 525 2.8E-150 T 13-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 SUPERFAMILY SSF52402 193 446 1.01E-56 T 13-10-2018 THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 Pfam PF02540 NAD synthase 216 292 3.7E-8 T 13-10-2018 IPR022310 NAD/GMP synthase THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 81 92 1.5E-7 T 13-10-2018 THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 54 63 1.5E-7 T 13-10-2018 THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 PRINTS PR00096 Glutamine amidotransferase superfamily signature 177 190 1.5E-7 T 13-10-2018 THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 Gene3D G3DSA:3.30.300.10 406 525 2.9E-51 T 13-10-2018 THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 SUPERFAMILY SSF52317 8 237 3.88E-56 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 Gene3D G3DSA:3.40.50.620 209 405 8.0E-75 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 10 24 1.8E-5 T 13-10-2018 THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 51 65 1.8E-5 T 13-10-2018 THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 81 97 1.8E-5 T 13-10-2018 THITH_12790 4f9f27acc104613a5b3e7340f6b50aa7 525 Pfam PF00958 GMP synthase C terminal domain 433 524 1.5E-42 T 13-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 THITH_07830 79900dec6235ef000cd216964b977e03 88 SUPERFAMILY SSF46785 28 85 1.31E-7 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_07830 79900dec6235ef000cd216964b977e03 88 Gene3D G3DSA:1.10.10.10 10 88 5.2E-7 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_07830 79900dec6235ef000cd216964b977e03 88 Pfam PF06163 Bacterial protein of unknown function (DUF977) 30 84 9.0E-7 T 13-10-2018 IPR010382 Protein of unknown function DUF977 THITH_04050 a95ef1149cf9b8627eb3d16ce5069378 491 Gene3D G3DSA:1.10.8.210 150 212 3.4E-5 T 13-10-2018 IPR037115 Sirohaem synthase, dimerisation domain superfamily GO:0006779|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 THITH_04050 a95ef1149cf9b8627eb3d16ce5069378 491 Hamap MF_01646 Siroheme synthase [cysG]. 1 462 53.789 T 13-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 THITH_04050 a95ef1149cf9b8627eb3d16ce5069378 491 Pfam PF10414 Sirohaem synthase dimerisation region 151 206 2.5E-22 T 13-10-2018 IPR019478 Sirohaem synthase, dimerisation domain GO:0006779|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 THITH_04050 a95ef1149cf9b8627eb3d16ce5069378 491 SUPERFAMILY SSF51735 1 112 6.99E-27 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_04050 a95ef1149cf9b8627eb3d16ce5069378 491 Pfam PF14824 Sirohaem biosynthesis protein central 119 145 6.7E-11 T 13-10-2018 IPR028281 Siroheme synthase, central domain KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 THITH_04050 a95ef1149cf9b8627eb3d16ce5069378 491 SUPERFAMILY SSF75615 114 211 3.66E-28 T 13-10-2018 THITH_04050 a95ef1149cf9b8627eb3d16ce5069378 491 PIRSF PIRSF036426 1 469 2.3E-203 T 13-10-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 THITH_04050 a95ef1149cf9b8627eb3d16ce5069378 491 Gene3D G3DSA:3.40.50.720 1 112 7.3E-38 T 13-10-2018 THITH_04050 a95ef1149cf9b8627eb3d16ce5069378 491 Gene3D G3DSA:3.30.160.110 113 148 4.3E-17 T 13-10-2018 THITH_04050 a95ef1149cf9b8627eb3d16ce5069378 491 Gene3D G3DSA:3.30.950.10 334 474 3.7E-48 T 13-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 THITH_04050 a95ef1149cf9b8627eb3d16ce5069378 491 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 220 429 2.0E-51 T 13-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 THITH_04050 a95ef1149cf9b8627eb3d16ce5069378 491 Gene3D G3DSA:3.40.1010.10 217 333 3.3E-45 T 13-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 THITH_04050 a95ef1149cf9b8627eb3d16ce5069378 491 Pfam PF13241 Putative NAD(P)-binding 6 115 2.0E-31 T 13-10-2018 THITH_04050 a95ef1149cf9b8627eb3d16ce5069378 491 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 4 206 1.3E-74 T 13-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 THITH_04050 a95ef1149cf9b8627eb3d16ce5069378 491 SUPERFAMILY SSF53790 218 461 5.23E-82 T 13-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 THITH_04050 a95ef1149cf9b8627eb3d16ce5069378 491 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 298 331 - T 13-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 THITH_04050 a95ef1149cf9b8627eb3d16ce5069378 491 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 218 453 3.2E-92 T 13-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 THITH_11965 ec186f827e649fc82fc51f0fe2396a2d 226 TIGRFAM TIGR02807 cas6_cmx6: CRISPR-associated protein Cas6, subtype MYXAN 17 215 8.9E-40 T 13-10-2018 IPR014174 CRISPR-associated protein, Cas6-related THITH_11965 ec186f827e649fc82fc51f0fe2396a2d 226 Pfam PF09559 Cas6 Crispr 18 217 3.5E-62 T 13-10-2018 IPR014174 CRISPR-associated protein, Cas6-related THITH_09720 b61c1fd9a7bba8e51a38559b8bcf616f 67 Pfam PF11127 Protein of unknown function (DUF2892) 2 56 2.0E-13 T 13-10-2018 IPR021309 Protein of unknown function DUF2892 THITH_02555 9b94701f0c8d6a3cba299e3379b3a37b 526 SUPERFAMILY SSF51261 233 479 1.67E-71 T 13-10-2018 IPR011055 Duplicated hybrid motif THITH_02555 9b94701f0c8d6a3cba299e3379b3a37b 526 Gene3D G3DSA:3.10.450.350 156 235 5.5E-8 T 13-10-2018 THITH_02555 9b94701f0c8d6a3cba299e3379b3a37b 526 Pfam PF01551 Peptidase family M23 382 478 1.9E-31 T 13-10-2018 IPR016047 Peptidase M23 THITH_02555 9b94701f0c8d6a3cba299e3379b3a37b 526 Gene3D G3DSA:2.70.70.10 354 484 4.2E-89 T 13-10-2018 IPR011055 Duplicated hybrid motif THITH_02555 9b94701f0c8d6a3cba299e3379b3a37b 526 Gene3D G3DSA:3.10.450.350 257 499 4.2E-89 T 13-10-2018 THITH_06735 d2dc4c4341109373c4701d43f5584e64 517 SUPERFAMILY SSF55961 352 491 3.11E-12 T 13-10-2018 THITH_06735 d2dc4c4341109373c4701d43f5584e64 517 Gene3D G3DSA:3.30.530.20 348 496 8.3E-8 T 13-10-2018 IPR023393 START-like domain superfamily THITH_06735 d2dc4c4341109373c4701d43f5584e64 517 Pfam PF11066 Protein of unknown function (DUF2867) 352 481 9.7E-20 T 13-10-2018 IPR021295 Protein of unknown function DUF2867 THITH_06735 d2dc4c4341109373c4701d43f5584e64 517 Pfam PF13460 NAD(P)H-binding 26 129 2.7E-15 T 13-10-2018 IPR016040 NAD(P)-binding domain THITH_06735 d2dc4c4341109373c4701d43f5584e64 517 SUPERFAMILY SSF51735 23 309 3.85E-45 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_06735 d2dc4c4341109373c4701d43f5584e64 517 Gene3D G3DSA:3.40.50.720 22 263 9.5E-37 T 13-10-2018 THITH_00775 976123185fc0af38c4d7257447b60c06 476 SUPERFAMILY SSF100950 62 297 3.72E-42 T 13-10-2018 IPR037171 NagB/RpiA transferase-like THITH_00775 976123185fc0af38c4d7257447b60c06 476 Pfam PF02589 LUD domain 68 296 6.8E-57 T 13-10-2018 IPR003741 LUD domain THITH_00775 976123185fc0af38c4d7257447b60c06 476 Gene3D G3DSA:3.40.50.10420 136 297 1.4E-16 T 13-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily THITH_00775 976123185fc0af38c4d7257447b60c06 476 Gene3D G3DSA:3.30.70.20 310 379 1.6E-6 T 13-10-2018 THITH_00775 976123185fc0af38c4d7257447b60c06 476 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 16 424 2.5E-137 T 13-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 THITH_00775 976123185fc0af38c4d7257447b60c06 476 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 314 325 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_00775 976123185fc0af38c4d7257447b60c06 476 SUPERFAMILY SSF46548 273 390 2.79E-17 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_00775 976123185fc0af38c4d7257447b60c06 476 Pfam PF13183 4Fe-4S dicluster domain 311 378 3.8E-9 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_10355 8ac1fd7e2ed5a94778f96a5adc1a9783 476 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 219 277 5.0E-5 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10355 8ac1fd7e2ed5a94778f96a5adc1a9783 476 SUPERFAMILY SSF54292 3 116 7.75E-32 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 THITH_10355 8ac1fd7e2ed5a94778f96a5adc1a9783 476 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 31 48 - T 13-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10355 8ac1fd7e2ed5a94778f96a5adc1a9783 476 SUPERFAMILY SSF54862 74 208 1.26E-27 T 13-10-2018 THITH_10355 8ac1fd7e2ed5a94778f96a5adc1a9783 476 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 4 75 4.4E-16 T 13-10-2018 THITH_10355 8ac1fd7e2ed5a94778f96a5adc1a9783 476 SUPERFAMILY SSF53706 214 398 7.2E-18 T 13-10-2018 THITH_10355 8ac1fd7e2ed5a94778f96a5adc1a9783 476 Gene3D G3DSA:2.20.25.90 216 279 1.7E-7 T 13-10-2018 THITH_10355 8ac1fd7e2ed5a94778f96a5adc1a9783 476 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 145 155 - T 13-10-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10355 8ac1fd7e2ed5a94778f96a5adc1a9783 476 SMART SM00929 82 122 1.4E-11 T 13-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10355 8ac1fd7e2ed5a94778f96a5adc1a9783 476 Gene3D G3DSA:3.10.20.740 1 120 1.5E-39 T 13-10-2018 THITH_10355 8ac1fd7e2ed5a94778f96a5adc1a9783 476 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 82 116 3.0E-14 T 13-10-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10355 8ac1fd7e2ed5a94778f96a5adc1a9783 476 SMART SM00926 216 283 7.3E-6 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10355 8ac1fd7e2ed5a94778f96a5adc1a9783 476 Gene3D G3DSA:3.30.70.20 128 205 1.5E-8 T 13-10-2018 THITH_16475 761e834e7a3e1647c02df4c4a8419205 391 Gene3D G3DSA:3.40.640.10 15 256 4.1E-136 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_16475 761e834e7a3e1647c02df4c4a8419205 391 Pfam PF00266 Aminotransferase class-V 4 361 4.5E-67 T 13-10-2018 IPR000192 Aminotransferase class V domain THITH_16475 761e834e7a3e1647c02df4c4a8419205 391 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 13-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site THITH_16475 761e834e7a3e1647c02df4c4a8419205 391 Gene3D G3DSA:3.90.1150.10 4 367 4.1E-136 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_16475 761e834e7a3e1647c02df4c4a8419205 391 SUPERFAMILY SSF53383 3 368 1.73E-98 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_16475 761e834e7a3e1647c02df4c4a8419205 391 PIRSF PIRSF005572 1 376 6.7E-122 T 13-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 THITH_07080 a8cf86f9ded1058179e8e00e97e67a5d 280 Pfam PF00793 DAHP synthetase I family 7 265 3.8E-68 T 13-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THITH_07080 a8cf86f9ded1058179e8e00e97e67a5d 280 Gene3D G3DSA:3.20.20.70 3 274 3.2E-104 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_07080 a8cf86f9ded1058179e8e00e97e67a5d 280 TIGRFAM TIGR01362 KDO8P_synth: 3-deoxy-8-phosphooctulonate synthase 13 268 2.4E-123 T 13-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THITH_07080 a8cf86f9ded1058179e8e00e97e67a5d 280 SUPERFAMILY SSF51569 2 269 4.49E-105 T 13-10-2018 THITH_07080 a8cf86f9ded1058179e8e00e97e67a5d 280 Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. 8 270 53.254 T 13-10-2018 IPR006269 3-deoxy-8-phosphooctulonate synthase GO:0005737|GO:0008676 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THITH_13470 45171401ba159bf2708d0ec5be333472 451 Gene3D G3DSA:3.10.350.10 398 451 1.1E-14 T 13-10-2018 IPR036779 LysM domain superfamily THITH_13470 45171401ba159bf2708d0ec5be333472 451 SMART SM00257 404 447 4.2E-14 T 13-10-2018 IPR018392 LysM domain THITH_13470 45171401ba159bf2708d0ec5be333472 451 Gene3D G3DSA:2.60.40.3500 23 137 1.3E-24 T 13-10-2018 THITH_13470 45171401ba159bf2708d0ec5be333472 451 SUPERFAMILY SSF53187 166 387 1.79E-54 T 13-10-2018 THITH_13470 45171401ba159bf2708d0ec5be333472 451 Pfam PF11741 AMIN domain 41 135 5.0E-14 T 13-10-2018 IPR021731 AMIN domain THITH_13470 45171401ba159bf2708d0ec5be333472 451 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 168 384 3.4E-49 T 13-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 THITH_13470 45171401ba159bf2708d0ec5be333472 451 SMART SM00646 228 384 8.0E-54 T 13-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 THITH_13470 45171401ba159bf2708d0ec5be333472 451 Pfam PF01476 LysM domain 405 447 2.4E-12 T 13-10-2018 IPR018392 LysM domain THITH_13470 45171401ba159bf2708d0ec5be333472 451 Gene3D G3DSA:3.40.630.40 154 393 4.4E-76 T 13-10-2018 THITH_13470 45171401ba159bf2708d0ec5be333472 451 SUPERFAMILY SSF54106 404 448 1.57E-10 T 13-10-2018 THITH_02135 7a8e8c961bada093c1c38868939ed377 175 Pfam PF11749 Protein of unknown function (DUF3305) 23 164 1.8E-37 T 13-10-2018 IPR021736 Protein of unknown function DUF3305 THITH_08150 d340d7c5b0a168e943a99fdae127a52c 202 Gene3D G3DSA:3.10.580.10 10 116 1.6E-13 T 13-10-2018 THITH_08150 d340d7c5b0a168e943a99fdae127a52c 202 Gene3D G3DSA:3.10.580.10 117 200 2.3E-16 T 13-10-2018 THITH_08150 d340d7c5b0a168e943a99fdae127a52c 202 Pfam PF00571 CBS domain 142 196 1.9E-10 T 13-10-2018 IPR000644 CBS domain THITH_08150 d340d7c5b0a168e943a99fdae127a52c 202 Pfam PF00571 CBS domain 61 113 2.7E-8 T 13-10-2018 IPR000644 CBS domain THITH_08150 d340d7c5b0a168e943a99fdae127a52c 202 SUPERFAMILY SSF54631 58 196 2.91E-30 T 13-10-2018 THITH_08150 d340d7c5b0a168e943a99fdae127a52c 202 SMART SM00116 67 115 8.5E-4 T 13-10-2018 IPR000644 CBS domain THITH_08150 d340d7c5b0a168e943a99fdae127a52c 202 SMART SM00116 149 197 3.3E-6 T 13-10-2018 IPR000644 CBS domain THITH_16455 00d2e7d03ac3bd29a941ac2032ec5dd2 227 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 1.1E-81 T 13-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 THITH_16455 00d2e7d03ac3bd29a941ac2032ec5dd2 227 SMART SM00382 27 216 2.8E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_16455 00d2e7d03ac3bd29a941ac2032ec5dd2 227 Gene3D G3DSA:3.40.50.300 1 226 7.1E-62 T 13-10-2018 THITH_16455 00d2e7d03ac3bd29a941ac2032ec5dd2 227 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_16455 00d2e7d03ac3bd29a941ac2032ec5dd2 227 SUPERFAMILY SSF52540 1 220 2.26E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16455 00d2e7d03ac3bd29a941ac2032ec5dd2 227 Pfam PF00005 ABC transporter 18 165 6.6E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_08650 6503b75d87f3872b89583e1adba1422d 209 SUPERFAMILY SSF52833 2 202 4.22E-39 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_08650 6503b75d87f3872b89583e1adba1422d 209 Gene3D G3DSA:3.40.30.10 1 207 1.1E-56 T 13-10-2018 THITH_08650 6503b75d87f3872b89583e1adba1422d 209 Pfam PF13743 Thioredoxin 3 178 1.5E-23 T 13-10-2018 THITH_15840 b62396b3696d01f41dd0c7a556c9612f 151 Gene3D G3DSA:2.20.25.10 1 31 2.0E-13 T 13-10-2018 THITH_15840 b62396b3696d01f41dd0c7a556c9612f 151 Pfam PF02566 OsmC-like protein 34 131 6.8E-18 T 13-10-2018 IPR003718 OsmC/Ohr family THITH_15840 b62396b3696d01f41dd0c7a556c9612f 151 SUPERFAMILY SSF82784 1 137 6.94E-40 T 13-10-2018 IPR036102 OsmC/Ohr superfamily THITH_15840 b62396b3696d01f41dd0c7a556c9612f 151 Gene3D G3DSA:3.30.300.20 39 138 1.7E-28 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta THITH_14040 d9bfa8c1875e960527eb97fd68d2e88f 214 SUPERFAMILY SSF52374 2 208 7.19E-56 T 13-10-2018 THITH_14040 d9bfa8c1875e960527eb97fd68d2e88f 214 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 4 206 4.7E-52 T 13-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 THITH_14040 d9bfa8c1875e960527eb97fd68d2e88f 214 Gene3D G3DSA:3.40.50.620 1 212 5.2E-64 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_14040 d9bfa8c1875e960527eb97fd68d2e88f 214 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 1 207 29.255 T 13-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 THITH_14040 d9bfa8c1875e960527eb97fd68d2e88f 214 Pfam PF01467 Cytidylyltransferase-like 5 180 3.4E-29 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THITH_14040 d9bfa8c1875e960527eb97fd68d2e88f 214 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 2 64 2.1E-9 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THITH_05700 e104821eee93d8fc8eddd1d10beabdb5 108 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 18 89 6.5E-7 T 13-10-2018 IPR009241 Toxin HigB-like THITH_05700 e104821eee93d8fc8eddd1d10beabdb5 108 PIRSF PIRSF028744 1 107 2.5E-43 T 13-10-2018 IPR014056 Addiction module killer protein, predicted THITH_05700 e104821eee93d8fc8eddd1d10beabdb5 108 TIGRFAM TIGR02683 upstrm_HI1419: putative addiction module killer protein 9 102 7.3E-38 T 13-10-2018 IPR014056 Addiction module killer protein, predicted THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 Gene3D G3DSA:3.40.50.300 219 355 1.8E-39 T 13-10-2018 THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 Pfam PF16124 RecQ zinc-binding 358 420 2.3E-20 T 13-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 26 478 2.1E-152 T 13-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 SMART SM00341 551 625 5.6E-9 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 Pfam PF00270 DEAD/DEAH box helicase 40 195 7.1E-16 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 SUPERFAMILY SSF52540 24 207 3.77E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 Gene3D G3DSA:3.40.50.300 14 218 3.1E-76 T 13-10-2018 THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 Gene3D G3DSA:1.10.10.10 356 540 4.5E-51 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 Gene3D G3DSA:1.10.150.80 550 626 2.7E-23 T 13-10-2018 THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 Pfam PF00271 Helicase conserved C-terminal domain 239 345 2.3E-16 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 SUPERFAMILY SSF52540 218 474 3.45E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 25 623 1.3E-238 T 13-10-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 SMART SM00490 265 346 8.6E-26 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 SUPERFAMILY SSF47819 548 624 5.45E-23 T 13-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 Pfam PF00570 HRDC domain 555 621 8.9E-21 T 13-10-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 SMART SM00956 427 530 1.8E-51 T 13-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 Pfam PF09382 RQC domain 422 533 1.1E-38 T 13-10-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 THITH_03775 241f3695fa187ae0375b93e71c8d7e34 627 SMART SM00487 32 226 3.3E-26 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_16255 69894de126e4e639f6a9ae1acf8f6afa 447 SUPERFAMILY SSF55073 258 445 2.83E-51 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_16255 69894de126e4e639f6a9ae1acf8f6afa 447 SMART SM00044 227 425 3.6E-11 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 THITH_16255 69894de126e4e639f6a9ae1acf8f6afa 447 Pfam PF00211 Adenylate and Guanylate cyclase catalytic domain 265 437 8.4E-32 T 13-10-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 THITH_16255 69894de126e4e639f6a9ae1acf8f6afa 447 Gene3D G3DSA:3.30.70.1230 252 447 3.5E-56 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_16255 69894de126e4e639f6a9ae1acf8f6afa 447 Gene3D G3DSA:1.20.1480.50 145 237 4.2E-6 T 13-10-2018 THITH_14110 9178a2788c17c95ca5749bacf10bdc1a 701 Pfam PF00092 von Willebrand factor type A domain 287 439 1.5E-5 T 13-10-2018 IPR002035 von Willebrand factor, type A THITH_14110 9178a2788c17c95ca5749bacf10bdc1a 701 Gene3D G3DSA:3.40.50.410 282 482 1.5E-11 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily THITH_14110 9178a2788c17c95ca5749bacf10bdc1a 701 SMART SM00327 285 480 1.1E-5 T 13-10-2018 IPR002035 von Willebrand factor, type A THITH_14110 9178a2788c17c95ca5749bacf10bdc1a 701 SUPERFAMILY SSF53300 285 479 2.09E-15 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 PRINTS PR00992 Alanine racemase signature 27 43 3.4E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 PRINTS PR00992 Alanine racemase signature 196 223 3.4E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 PRINTS PR00992 Alanine racemase signature 62 80 3.4E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 PRINTS PR00992 Alanine racemase signature 291 308 3.4E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 PRINTS PR00992 Alanine racemase signature 253 268 3.4E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 PRINTS PR00992 Alanine racemase signature 156 167 3.4E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 PRINTS PR00992 Alanine racemase signature 270 285 3.4E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 PRINTS PR00992 Alanine racemase signature 121 133 3.4E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 PRINTS PR00992 Alanine racemase signature 343 356 3.4E-60 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 SMART SM01005 237 361 1.9E-60 T 13-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 TIGRFAM TIGR00492 alr: alanine racemase 5 357 2.3E-94 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 Gene3D G3DSA:2.40.37.10 222 355 1.9E-111 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 Gene3D G3DSA:3.20.20.10 12 221 1.9E-111 T 13-10-2018 IPR029066 PLP-binding barrel THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 32 42 - T 13-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 Hamap MF_01201 Alanine racemase. 2 361 31.275 T 13-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 Pfam PF01168 Alanine racemase, N-terminal domain 11 223 2.8E-55 T 13-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 SUPERFAMILY SSF50621 232 356 5.58E-44 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 SUPERFAMILY SSF51419 11 238 3.93E-54 T 13-10-2018 IPR029066 PLP-binding barrel THITH_03565 4dca948876aeacb1d2e18fe9a8fd1f23 361 Pfam PF00842 Alanine racemase, C-terminal domain 237 356 1.3E-40 T 13-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THITH_12555 0de40e6696195333d75a4fff668e7819 256 PRINTS PR01459 KCNQ voltage-gated potassium channel family signature 83 102 1.9E-7 T 13-10-2018 IPR003937 Potassium channel, voltage dependent, KCNQ GO:0005249|GO:0006813|GO:0016020 Reactome: R-HSA-1296072 THITH_12555 0de40e6696195333d75a4fff668e7819 256 PRINTS PR01459 KCNQ voltage-gated potassium channel family signature 63 82 1.9E-7 T 13-10-2018 IPR003937 Potassium channel, voltage dependent, KCNQ GO:0005249|GO:0006813|GO:0016020 Reactome: R-HSA-1296072 THITH_12555 0de40e6696195333d75a4fff668e7819 256 PRINTS PR01459 KCNQ voltage-gated potassium channel family signature 139 158 1.9E-7 T 13-10-2018 IPR003937 Potassium channel, voltage dependent, KCNQ GO:0005249|GO:0006813|GO:0016020 Reactome: R-HSA-1296072 THITH_12555 0de40e6696195333d75a4fff668e7819 256 SUPERFAMILY SSF81324 24 239 2.75E-45 T 13-10-2018 THITH_12555 0de40e6696195333d75a4fff668e7819 256 Pfam PF00520 Ion transport protein 26 243 4.6E-26 T 13-10-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 THITH_12555 0de40e6696195333d75a4fff668e7819 256 PRINTS PR00169 Potassium channel signature 152 175 2.2E-25 T 13-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 THITH_12555 0de40e6696195333d75a4fff668e7819 256 PRINTS PR00169 Potassium channel signature 212 238 2.2E-25 T 13-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 THITH_12555 0de40e6696195333d75a4fff668e7819 256 PRINTS PR00169 Potassium channel signature 55 78 2.2E-25 T 13-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 THITH_12555 0de40e6696195333d75a4fff668e7819 256 PRINTS PR00169 Potassium channel signature 183 205 2.2E-25 T 13-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 THITH_12555 0de40e6696195333d75a4fff668e7819 256 PRINTS PR00169 Potassium channel signature 123 149 2.2E-25 T 13-10-2018 IPR028325 Voltage-gated potassium channel GO:0005249|GO:0006813|GO:0008076 Reactome: R-HSA-1296072 THITH_12555 0de40e6696195333d75a4fff668e7819 256 Gene3D G3DSA:1.10.287.70 20 242 1.6E-55 T 13-10-2018 THITH_16975 3c24dd7eab5895e1a2d7241a496ca816 282 SMART SM00470 30 119 1.0E-35 T 13-10-2018 IPR003115 ParB/Sulfiredoxin THITH_16975 3c24dd7eab5895e1a2d7241a496ca816 282 Gene3D G3DSA:3.90.1530.30 43 105 6.9E-29 T 13-10-2018 THITH_16975 3c24dd7eab5895e1a2d7241a496ca816 282 Pfam PF02195 ParB-like nuclease domain 32 119 4.4E-26 T 13-10-2018 IPR003115 ParB/Sulfiredoxin THITH_16975 3c24dd7eab5895e1a2d7241a496ca816 282 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 29 197 7.2E-57 T 13-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 THITH_16975 3c24dd7eab5895e1a2d7241a496ca816 282 SUPERFAMILY SSF110849 29 175 9.94E-33 T 13-10-2018 IPR036086 ParB/Sulfiredoxin superfamily THITH_16975 3c24dd7eab5895e1a2d7241a496ca816 282 Gene3D G3DSA:1.10.10.2830 106 219 5.1E-34 T 13-10-2018 THITH_01320 f24fa2bdfe47793e28e6bce27addf8c3 199 SUPERFAMILY SSF46689 4 69 1.21E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_01320 f24fa2bdfe47793e28e6bce27addf8c3 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 1.0E-11 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THITH_01320 f24fa2bdfe47793e28e6bce27addf8c3 199 Gene3D G3DSA:1.10.357.10 6 194 1.2E-49 T 13-10-2018 THITH_01320 f24fa2bdfe47793e28e6bce27addf8c3 199 SUPERFAMILY SSF48498 80 191 4.77E-19 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily THITH_01320 f24fa2bdfe47793e28e6bce27addf8c3 199 Pfam PF16925 Bacterial transcriptional repressor C-terminal 79 182 7.7E-10 T 13-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THITH_10840 5c3013db64004e5fb4fbc8aba61c1a5c 309 Gene3D G3DSA:3.40.1090.10 134 262 6.6E-18 T 13-10-2018 THITH_10840 5c3013db64004e5fb4fbc8aba61c1a5c 309 SUPERFAMILY SSF52151 34 288 1.88E-47 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase THITH_10840 5c3013db64004e5fb4fbc8aba61c1a5c 309 Pfam PF01734 Patatin-like phospholipase 39 214 1.6E-26 T 13-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 THITH_10840 5c3013db64004e5fb4fbc8aba61c1a5c 309 Gene3D G3DSA:3.40.1090.20 35 128 6.5E-11 T 13-10-2018 THITH_00970 b980d29e317d8a38363b9c93ea8ee92f 312 Pfam PF02401 LytB protein 3 283 2.8E-90 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 THITH_00970 b980d29e317d8a38363b9c93ea8ee92f 312 Gene3D G3DSA:3.40.1010.20 6 283 2.1E-109 T 13-10-2018 THITH_00970 b980d29e317d8a38363b9c93ea8ee92f 312 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 287 38.702 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 THITH_00970 b980d29e317d8a38363b9c93ea8ee92f 312 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3 285 4.5E-100 T 13-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 THITH_00970 b980d29e317d8a38363b9c93ea8ee92f 312 Gene3D G3DSA:3.40.50.11270 12 96 2.1E-109 T 13-10-2018 THITH_00970 b980d29e317d8a38363b9c93ea8ee92f 312 Gene3D G3DSA:3.40.1010.20 97 197 2.1E-109 T 13-10-2018 THITH_11310 e95b183ec001e18795f289529c4ff910 163 SUPERFAMILY SSF75169 44 157 2.68E-14 T 13-10-2018 IPR027396 DsrEFH-like THITH_11310 e95b183ec001e18795f289529c4ff910 163 Pfam PF02635 DsrE/DsrF-like family 46 158 1.0E-8 T 13-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THITH_11310 e95b183ec001e18795f289529c4ff910 163 Gene3D G3DSA:3.40.1260.10 42 163 9.1E-13 T 13-10-2018 IPR027396 DsrEFH-like THITH_06390 92bec13a824acc623f901e46240adb2c 392 Gene3D G3DSA:3.40.50.150 115 381 4.1E-95 T 13-10-2018 THITH_06390 92bec13a824acc623f901e46240adb2c 392 SUPERFAMILY SSF53335 117 377 3.22E-72 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_06390 92bec13a824acc623f901e46240adb2c 392 Pfam PF02353 Mycolic acid cyclopropane synthetase 109 372 8.6E-90 T 13-10-2018 THITH_06390 92bec13a824acc623f901e46240adb2c 392 PIRSF PIRSF003085 4 391 8.7E-126 T 13-10-2018 IPR003333 Mycolic acid cyclopropane synthase GO:0008610 THITH_15205 4c2a8775fb4430c757de454e3b88f809 365 SUPERFAMILY SSF52540 16 252 4.05E-77 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_15205 4c2a8775fb4430c757de454e3b88f809 365 Gene3D G3DSA:2.40.50.940 234 355 2.7E-10 T 13-10-2018 THITH_15205 4c2a8775fb4430c757de454e3b88f809 365 Pfam PF00005 ABC transporter 30 173 1.8E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_15205 4c2a8775fb4430c757de454e3b88f809 365 Gene3D G3DSA:2.40.50.140 292 347 2.7E-10 T 13-10-2018 THITH_15205 4c2a8775fb4430c757de454e3b88f809 365 SMART SM00382 38 223 6.1E-20 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_15205 4c2a8775fb4430c757de454e3b88f809 365 Gene3D G3DSA:3.40.50.300 14 233 1.8E-58 T 13-10-2018 THITH_15205 4c2a8775fb4430c757de454e3b88f809 365 Pfam PF08402 TOBE domain 285 355 3.3E-11 T 13-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 THITH_15205 4c2a8775fb4430c757de454e3b88f809 365 SUPERFAMILY SSF50331 251 356 3.37E-14 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal THITH_15205 4c2a8775fb4430c757de454e3b88f809 365 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_01115 de2443b7d65d6302fd43908983bfd0d5 378 SUPERFAMILY SSF143422 16 194 2.88E-17 T 13-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 THITH_01115 de2443b7d65d6302fd43908983bfd0d5 378 SMART SM01321 12 188 1.5E-4 T 13-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THITH_08670 c5d4d9ebefea8d9d2fede91da9743025 348 SMART SM00382 21 164 6.9E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_08670 c5d4d9ebefea8d9d2fede91da9743025 348 Gene3D G3DSA:3.40.50.300 11 165 5.1E-23 T 13-10-2018 THITH_08670 c5d4d9ebefea8d9d2fede91da9743025 348 Pfam PF07728 AAA domain (dynein-related subfamily) 24 120 3.1E-9 T 13-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 THITH_08670 c5d4d9ebefea8d9d2fede91da9743025 348 SUPERFAMILY SSF52540 22 169 7.03E-19 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 Pfam PF00595 PDZ domain (Also known as DHR or GLGF) 372 425 5.6E-8 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 SUPERFAMILY SSF50156 219 343 2.63E-26 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 Gene3D G3DSA:2.30.42.10 256 359 1.1E-28 T 13-10-2018 THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 Gene3D G3DSA:2.30.42.10 360 449 4.5E-19 T 13-10-2018 THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 Pfam PF13365 Trypsin-like peptidase domain 87 222 2.1E-34 T 13-10-2018 THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 Pfam PF13180 PDZ domain 261 346 4.1E-17 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 SUPERFAMILY SSF50156 373 444 8.15E-13 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 34 447 3.5E-145 T 13-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 SMART SM00228 261 343 1.7E-17 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 SMART SM00228 363 441 2.9E-6 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 PRINTS PR00834 HtrA/DegQ protease family signature 158 182 9.0E-54 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 PRINTS PR00834 HtrA/DegQ protease family signature 193 210 9.0E-54 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 PRINTS PR00834 HtrA/DegQ protease family signature 97 109 9.0E-54 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 PRINTS PR00834 HtrA/DegQ protease family signature 215 232 9.0E-54 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 PRINTS PR00834 HtrA/DegQ protease family signature 118 138 9.0E-54 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 PRINTS PR00834 HtrA/DegQ protease family signature 301 313 9.0E-54 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 Gene3D G3DSA:2.40.10.120 32 254 1.5E-84 T 13-10-2018 THITH_01485 12778542c6e1c66a47d2efb9733ee305 449 SUPERFAMILY SSF50494 33 257 4.61E-66 T 13-10-2018 IPR009003 Peptidase S1, PA clan THITH_01080 d92f4832c9155d4bf339e22e4155c404 387 SUPERFAMILY SSF140931 86 286 1.44E-31 T 13-10-2018 IPR036597 Fido-like domain superfamily THITH_01080 d92f4832c9155d4bf339e22e4155c404 387 Pfam PF02661 Fic/DOC family 110 217 2.1E-20 T 13-10-2018 IPR003812 Fido domain THITH_01080 d92f4832c9155d4bf339e22e4155c404 387 Gene3D G3DSA:1.10.3290.10 22 296 4.5E-51 T 13-10-2018 IPR036597 Fido-like domain superfamily THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 SMART SM00493 3 103 1.2E-29 T 13-10-2018 IPR006171 TOPRIM domain THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 166 184 8.4E-36 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 8.4E-36 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 380 396 8.4E-36 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 302 311 8.4E-36 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 487 501 8.4E-36 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 Pfam PF01751 Toprim domain 5 117 1.2E-25 T 13-10-2018 IPR006171 TOPRIM domain THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 289 311 - T 13-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 Gene3D G3DSA:3.40.50.140 1 138 6.0E-48 T 13-10-2018 THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 Gene3D G3DSA:1.10.460.10 139 564 1.1E-173 T 13-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 SMART SM00437 252 524 3.6E-118 T 13-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 674 52.856 T 13-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 616 6.6E-233 T 13-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 Gene3D G3DSA:1.10.290.10 260 395 1.1E-173 T 13-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 Pfam PF13368 Topoisomerase C-terminal repeat 716 764 8.5E-17 T 13-10-2018 IPR025589 Topoisomerase C-terminal repeat THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 Pfam PF13368 Topoisomerase C-terminal repeat 593 653 4.3E-12 T 13-10-2018 IPR025589 Topoisomerase C-terminal repeat THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 Pfam PF13368 Topoisomerase C-terminal repeat 656 705 1.1E-17 T 13-10-2018 IPR025589 Topoisomerase C-terminal repeat THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 SMART SM00436 108 196 1.8E-49 T 13-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 Pfam PF01131 DNA topoisomerase 134 562 6.7E-129 T 13-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 SUPERFAMILY SSF56712 3 600 4.84E-189 T 13-10-2018 IPR023405 DNA topoisomerase, type IA, core domain THITH_15605 6215cb460d88f6c89b85e82719403ecb 853 Gene3D G3DSA:2.70.20.10 188 471 1.1E-173 T 13-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 THITH_16320 708b2e74d067b109369d775dda041946 393 Gene3D G3DSA:3.30.300.10 12 271 1.6E-175 T 13-10-2018 THITH_16320 708b2e74d067b109369d775dda041946 393 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 384 56.969 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_16320 708b2e74d067b109369d775dda041946 393 Pfam PF02772 S-adenosylmethionine synthetase, central domain 115 232 4.1E-43 T 13-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_16320 708b2e74d067b109369d775dda041946 393 SUPERFAMILY SSF55973 235 383 1.18E-68 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_16320 708b2e74d067b109369d775dda041946 393 PIRSF PIRSF000497 1 385 8.5E-172 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_16320 708b2e74d067b109369d775dda041946 393 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 235 373 1.1E-67 T 13-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_16320 708b2e74d067b109369d775dda041946 393 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 380 1.6E-183 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_16320 708b2e74d067b109369d775dda041946 393 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 260 268 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_16320 708b2e74d067b109369d775dda041946 393 Gene3D G3DSA:3.30.300.10 103 376 1.6E-175 T 13-10-2018 THITH_16320 708b2e74d067b109369d775dda041946 393 Gene3D G3DSA:3.30.300.10 6 234 1.6E-175 T 13-10-2018 THITH_16320 708b2e74d067b109369d775dda041946 393 SUPERFAMILY SSF55973 112 233 2.79E-50 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_16320 708b2e74d067b109369d775dda041946 393 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 117 127 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_16320 708b2e74d067b109369d775dda041946 393 SUPERFAMILY SSF55973 4 111 1.53E-45 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_16320 708b2e74d067b109369d775dda041946 393 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 102 2.8E-42 T 13-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_04880 746e7fb7d56f5cc1e4d2fc1b40ef3814 347 SUPERFAMILY SSF48452 275 329 9.83E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_04880 746e7fb7d56f5cc1e4d2fc1b40ef3814 347 Gene3D G3DSA:1.25.40.10 249 338 2.7E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_07275 35d8060c5f9288109fe7f379e035bcec 283 SUPERFAMILY SSF110857 131 253 3.66E-8 T 13-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily THITH_07275 35d8060c5f9288109fe7f379e035bcec 283 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 1 118 5.9E-19 T 13-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like THITH_07275 35d8060c5f9288109fe7f379e035bcec 283 SUPERFAMILY SSF110857 1 124 4.32E-26 T 13-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily THITH_07275 35d8060c5f9288109fe7f379e035bcec 283 Gene3D G3DSA:3.10.490.10 125 280 1.1E-17 T 13-10-2018 THITH_07275 35d8060c5f9288109fe7f379e035bcec 283 Gene3D G3DSA:3.10.490.10 1 124 3.1E-24 T 13-10-2018 THITH_11115 a87354256e70cab57b669f2cbfdd57dc 627 Gene3D G3DSA:3.40.50.300 428 615 6.0E-36 T 13-10-2018 THITH_11115 a87354256e70cab57b669f2cbfdd57dc 627 Pfam PF13361 UvrD-like helicase C-terminal domain 540 601 1.2E-13 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 THITH_11115 a87354256e70cab57b669f2cbfdd57dc 627 Gene3D G3DSA:3.40.50.300 235 414 1.0E-21 T 13-10-2018 THITH_11115 a87354256e70cab57b669f2cbfdd57dc 627 SUPERFAMILY SSF52540 235 604 1.47E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_11115 a87354256e70cab57b669f2cbfdd57dc 627 Pfam PF13245 AAA domain 246 403 1.5E-8 T 13-10-2018 THITH_11115 a87354256e70cab57b669f2cbfdd57dc 627 Pfam PF13361 UvrD-like helicase C-terminal domain 426 530 8.4E-9 T 13-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 THITH_11115 a87354256e70cab57b669f2cbfdd57dc 627 Pfam PF08378 Nuclease-related domain 18 114 3.9E-13 T 13-10-2018 IPR011528 Nuclease-related domain, NERD THITH_00295 f8ec9b452cb49c56b5d9193358f059de 76 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 41 2.6E-8 T 13-10-2018 THITH_00295 f8ec9b452cb49c56b5d9193358f059de 76 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 49 8.0E-10 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THITH_00295 f8ec9b452cb49c56b5d9193358f059de 76 SUPERFAMILY SSF143120 1 41 6.54E-9 T 13-10-2018 IPR036165 YefM-like superfamily THITH_00295 f8ec9b452cb49c56b5d9193358f059de 76 Gene3D G3DSA:3.40.1620.10 1 39 8.0E-9 T 13-10-2018 THITH_04945 83b193c4bfe732858c0c1fbc3b32cdea 767 Gene3D G3DSA:3.40.50.300 378 681 8.6E-117 T 13-10-2018 THITH_04945 83b193c4bfe732858c0c1fbc3b32cdea 767 SUPERFAMILY SSF52540 355 667 2.12E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_04945 83b193c4bfe732858c0c1fbc3b32cdea 767 Pfam PF09397 Ftsk gamma domain 702 762 5.6E-28 T 13-10-2018 IPR018541 FtsK gamma domain THITH_04945 83b193c4bfe732858c0c1fbc3b32cdea 767 SUPERFAMILY SSF46785 701 764 4.36E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_04945 83b193c4bfe732858c0c1fbc3b32cdea 767 SMART SM00843 700 765 8.1E-39 T 13-10-2018 IPR018541 FtsK gamma domain THITH_04945 83b193c4bfe732858c0c1fbc3b32cdea 767 Gene3D G3DSA:1.10.10.10 697 761 3.8E-28 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_04945 83b193c4bfe732858c0c1fbc3b32cdea 767 Pfam PF01580 FtsK/SpoIIIE family 381 595 9.2E-66 T 13-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 THITH_04945 83b193c4bfe732858c0c1fbc3b32cdea 767 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 23 194 3.2E-39 T 13-10-2018 IPR025199 DNA translocase FtsK, 4TM region THITH_04945 83b193c4bfe732858c0c1fbc3b32cdea 767 Gene3D G3DSA:3.30.980.40 273 377 9.5E-34 T 13-10-2018 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 Gene3D G3DSA:3.10.310.40 758 866 1.9E-29 T 13-10-2018 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 Gene3D G3DSA:3.30.54.20 618 670 4.5E-49 T 13-10-2018 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 SUPERFAMILY SSF55186 550 700 2.75E-46 T 13-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 869 195.275 T 13-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 848 0.0 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 Gene3D G3DSA:3.30.980.10 556 690 4.5E-49 T 13-10-2018 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 Pfam PF02272 DHHA1 domain 727 865 1.3E-25 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 Gene3D G3DSA:2.40.30.130 459 545 1.7E-11 T 13-10-2018 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 SUPERFAMILY SSF55681 2 249 2.98E-108 T 13-10-2018 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 SMART SM00863 647 689 9.0E-20 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 647 689 1.2E-16 T 13-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 PRINTS PR00980 Alanyl-tRNA synthetase signature 74 85 3.8E-32 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 PRINTS PR00980 Alanyl-tRNA synthetase signature 276 292 3.8E-32 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 PRINTS PR00980 Alanyl-tRNA synthetase signature 230 243 3.8E-32 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 PRINTS PR00980 Alanyl-tRNA synthetase signature 203 214 3.8E-32 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 PRINTS PR00980 Alanyl-tRNA synthetase signature 300 313 3.8E-32 T 13-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 Pfam PF01411 tRNA synthetases class II (A) 5 546 6.1E-218 T 13-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 SUPERFAMILY SSF101353 250 458 3.79E-61 T 13-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 Gene3D G3DSA:3.30.930.10 1 246 7.6E-115 T 13-10-2018 THITH_09380 f67d432c7fd60beaa675fcfbe3bdc2e3 871 SUPERFAMILY SSF50447 449 545 2.37E-17 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THITH_17385 00d5fd062f77ed0c7639b1a70722eb74 438 Gene3D G3DSA:3.30.559.10 206 438 3.1E-98 T 13-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 THITH_17385 00d5fd062f77ed0c7639b1a70722eb74 438 SUPERFAMILY SSF52777 208 437 2.27E-91 T 13-10-2018 THITH_17385 00d5fd062f77ed0c7639b1a70722eb74 438 Gene3D G3DSA:2.40.50.100 1 103 9.1E-20 T 13-10-2018 THITH_17385 00d5fd062f77ed0c7639b1a70722eb74 438 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 30 59 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 THITH_17385 00d5fd062f77ed0c7639b1a70722eb74 438 SUPERFAMILY SSF51230 6 98 2.36E-22 T 13-10-2018 IPR011053 Single hybrid motif THITH_17385 00d5fd062f77ed0c7639b1a70722eb74 438 Pfam PF02817 e3 binding domain 128 161 7.5E-11 T 13-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 THITH_17385 00d5fd062f77ed0c7639b1a70722eb74 438 SUPERFAMILY SSF47005 124 165 3.79E-10 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 THITH_17385 00d5fd062f77ed0c7639b1a70722eb74 438 Pfam PF00364 Biotin-requiring enzyme 7 79 2.3E-16 T 13-10-2018 IPR000089 Biotin/lipoyl attachment THITH_17385 00d5fd062f77ed0c7639b1a70722eb74 438 TIGRFAM TIGR01347 sucB: dihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase (succinyl-transferring) complex 8 437 2.0E-163 T 13-10-2018 IPR006255 Dihydrolipoamide succinyltransferase GO:0004149|GO:0006099|GO:0045252 KEGG: 00020+2.3.1.61|KEGG: 00310+2.3.1.61|MetaCyc: PWY-5084|Reactome: R-HSA-389661|Reactome: R-HSA-71064|Reactome: R-HSA-71403 THITH_17385 00d5fd062f77ed0c7639b1a70722eb74 438 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 208 436 5.1E-82 T 13-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 THITH_17385 00d5fd062f77ed0c7639b1a70722eb74 438 Gene3D G3DSA:4.10.320.10 121 166 1.8E-14 T 13-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 THITH_09600 5e2eb836512fe60a3efcdab29d76cc6c 426 PIRSF PIRSF000538 7 424 4.3E-45 T 13-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 THITH_09600 5e2eb836512fe60a3efcdab29d76cc6c 426 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 307 422 1.0E-11 T 13-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 THITH_09600 5e2eb836512fe60a3efcdab29d76cc6c 426 SUPERFAMILY SSF53067 247 422 8.81E-17 T 13-10-2018 THITH_09600 5e2eb836512fe60a3efcdab29d76cc6c 426 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 9 235 9.9E-21 T 13-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 THITH_09600 5e2eb836512fe60a3efcdab29d76cc6c 426 Gene3D G3DSA:3.30.420.40 233 425 2.9E-26 T 13-10-2018 THITH_09600 5e2eb836512fe60a3efcdab29d76cc6c 426 Gene3D G3DSA:3.30.420.40 4 232 6.8E-42 T 13-10-2018 THITH_09600 5e2eb836512fe60a3efcdab29d76cc6c 426 SUPERFAMILY SSF53067 7 234 2.3E-36 T 13-10-2018 THITH_11890 c4eb12eb63f91c79cae99f08039187da 469 Gene3D G3DSA:3.40.50.300 2 160 8.2E-42 T 13-10-2018 THITH_11890 c4eb12eb63f91c79cae99f08039187da 469 PIRSF PIRSF006485 1 446 3.3E-160 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 THITH_11890 c4eb12eb63f91c79cae99f08039187da 469 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 360 438 4.7E-26 T 13-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like THITH_11890 c4eb12eb63f91c79cae99f08039187da 469 SMART SM00382 1 141 3.0 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_11890 c4eb12eb63f91c79cae99f08039187da 469 SMART SM00382 181 324 0.22 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_11890 c4eb12eb63f91c79cae99f08039187da 469 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 72 90 4.0E-9 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_11890 c4eb12eb63f91c79cae99f08039187da 469 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 4.0E-9 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_11890 c4eb12eb63f91c79cae99f08039187da 469 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 4 157 1.1E-22 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THITH_11890 c4eb12eb63f91c79cae99f08039187da 469 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 183 341 2.3E-21 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THITH_11890 c4eb12eb63f91c79cae99f08039187da 469 SUPERFAMILY SSF52540 4 162 1.84E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_11890 c4eb12eb63f91c79cae99f08039187da 469 Gene3D G3DSA:3.30.300.20 358 441 2.2E-21 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta THITH_11890 c4eb12eb63f91c79cae99f08039187da 469 SUPERFAMILY SSF52540 137 444 4.91E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_11890 c4eb12eb63f91c79cae99f08039187da 469 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 3 438 4.4E-162 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 THITH_11890 c4eb12eb63f91c79cae99f08039187da 469 Hamap MF_00195 GTPase Der [der]. 2 441 36.834 T 13-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 THITH_11890 c4eb12eb63f91c79cae99f08039187da 469 Gene3D G3DSA:3.40.50.300 181 354 3.4E-46 T 13-10-2018 THITH_11890 c4eb12eb63f91c79cae99f08039187da 469 Pfam PF01926 50S ribosome-binding GTPase 5 119 3.0E-24 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_11890 c4eb12eb63f91c79cae99f08039187da 469 Pfam PF01926 50S ribosome-binding GTPase 184 302 8.4E-24 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_07630 849ccaf726e2b905d4de865c18391502 212 Pfam PF00072 Response regulator receiver domain 9 117 2.5E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_07630 849ccaf726e2b905d4de865c18391502 212 SUPERFAMILY SSF52172 7 135 8.97E-34 T 13-10-2018 IPR011006 CheY-like superfamily THITH_07630 849ccaf726e2b905d4de865c18391502 212 SUPERFAMILY SSF46894 136 200 7.14E-19 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THITH_07630 849ccaf726e2b905d4de865c18391502 212 SMART SM00448 7 118 6.4E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_07630 849ccaf726e2b905d4de865c18391502 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 187 4.3E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_07630 849ccaf726e2b905d4de865c18391502 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 145 159 4.3E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_07630 849ccaf726e2b905d4de865c18391502 212 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 175 4.3E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_07630 849ccaf726e2b905d4de865c18391502 212 Gene3D G3DSA:1.10.10.10 135 201 2.0E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_07630 849ccaf726e2b905d4de865c18391502 212 SMART SM00421 142 199 2.7E-23 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_07630 849ccaf726e2b905d4de865c18391502 212 Gene3D G3DSA:3.40.50.2300 4 131 2.1E-42 T 13-10-2018 THITH_07630 849ccaf726e2b905d4de865c18391502 212 Pfam PF00196 Bacterial regulatory proteins, luxR family 144 199 1.9E-21 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_07630 849ccaf726e2b905d4de865c18391502 212 ProSitePatterns PS00622 LuxR-type HTH domain signature. 159 186 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_13000 faa207e4970085c339d7649410203a13 116 PRINTS PR01651 Protein-export SecG membrane protein signature 39 55 6.2E-37 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THITH_13000 faa207e4970085c339d7649410203a13 116 PRINTS PR01651 Protein-export SecG membrane protein signature 24 38 6.2E-37 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THITH_13000 faa207e4970085c339d7649410203a13 116 PRINTS PR01651 Protein-export SecG membrane protein signature 55 77 6.2E-37 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THITH_13000 faa207e4970085c339d7649410203a13 116 PRINTS PR01651 Protein-export SecG membrane protein signature 4 24 6.2E-37 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THITH_13000 faa207e4970085c339d7649410203a13 116 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 4 74 2.5E-28 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THITH_13000 faa207e4970085c339d7649410203a13 116 Pfam PF03840 Preprotein translocase SecG subunit 5 74 5.1E-24 T 13-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 THITH_04405 0b094351dfdc709605b4c7fab37be985 363 SUPERFAMILY SSF117916 2 83 3.6E-13 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily THITH_04405 0b094351dfdc709605b4c7fab37be985 363 ProSitePatterns PS01215 Mrp family signature. 204 220 - T 13-10-2018 IPR000808 Mrp, conserved site GO:0005524 THITH_04405 0b094351dfdc709605b4c7fab37be985 363 Gene3D G3DSA:3.40.50.300 85 340 4.6E-88 T 13-10-2018 THITH_04405 0b094351dfdc709605b4c7fab37be985 363 SUPERFAMILY SSF52540 90 325 5.15E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_04405 0b094351dfdc709605b4c7fab37be985 363 Pfam PF01883 Iron-sulfur cluster assembly protein 8 78 7.6E-14 T 13-10-2018 IPR002744 MIP18 family-like THITH_04405 0b094351dfdc709605b4c7fab37be985 363 Hamap MF_02040 Iron-sulfur cluster carrier protein. 93 341 38.405 T 13-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein THITH_04405 0b094351dfdc709605b4c7fab37be985 363 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 98 339 2.6E-104 T 13-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 THITH_06085 c2f4b98b39a4afdff3a546c96b7a0b4c 621 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 350 599 1.1E-78 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THITH_06085 c2f4b98b39a4afdff3a546c96b7a0b4c 621 SUPERFAMILY SSF82866 344 613 3.53E-47 T 13-10-2018 THITH_06085 c2f4b98b39a4afdff3a546c96b7a0b4c 621 Pfam PF02355 Protein export membrane protein 439 607 9.0E-23 T 13-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial THITH_06085 c2f4b98b39a4afdff3a546c96b7a0b4c 621 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 3 621 46.323 T 13-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 THITH_06085 c2f4b98b39a4afdff3a546c96b7a0b4c 621 Pfam PF07549 SecD/SecF GG Motif 117 138 6.5E-5 T 13-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site THITH_06085 c2f4b98b39a4afdff3a546c96b7a0b4c 621 Gene3D G3DSA:3.30.1360.200 281 437 7.9E-48 T 13-10-2018 THITH_06085 c2f4b98b39a4afdff3a546c96b7a0b4c 621 Gene3D G3DSA:3.30.70.3400 228 443 7.9E-48 T 13-10-2018 THITH_06085 c2f4b98b39a4afdff3a546c96b7a0b4c 621 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 123 606 7.0E-144 T 13-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 THITH_06085 c2f4b98b39a4afdff3a546c96b7a0b4c 621 Pfam PF13721 SecD export protein N-terminal TM region 3 103 3.4E-27 T 13-10-2018 IPR027398 SecD export protein N-terminal TM domain THITH_06085 c2f4b98b39a4afdff3a546c96b7a0b4c 621 Gene3D G3DSA:1.20.1640.10 453 607 1.3E-9 T 13-10-2018 THITH_14900 6ad3227aaa2587aa07a4996dca5988d7 802 Gene3D G3DSA:1.10.3810.10 53 248 1.2E-78 T 13-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_14900 6ad3227aaa2587aa07a4996dca5988d7 802 Pfam PF00905 Penicillin binding protein transpeptidase domain 422 599 3.7E-20 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THITH_14900 6ad3227aaa2587aa07a4996dca5988d7 802 Gene3D G3DSA:2.40.50.140 320 417 9.5E-8 T 13-10-2018 THITH_14900 6ad3227aaa2587aa07a4996dca5988d7 802 SUPERFAMILY SSF53955 47 261 3.66E-77 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily THITH_14900 6ad3227aaa2587aa07a4996dca5988d7 802 SUPERFAMILY SSF56601 215 777 7.34E-119 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like THITH_14900 6ad3227aaa2587aa07a4996dca5988d7 802 Pfam PF00912 Transglycosylase 59 233 1.6E-65 T 13-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_14900 6ad3227aaa2587aa07a4996dca5988d7 802 Pfam PF17092 Penicillin-binding protein OB-like domain 320 420 1.1E-16 T 13-10-2018 IPR031376 Penicillin-binding protein, OB-like domain KEGG: 00550+2.4.1.129+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_14900 6ad3227aaa2587aa07a4996dca5988d7 802 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 69 728 5.4E-174 T 13-10-2018 THITH_02010 aca06b0b7d2884421dfad79a1462b01f 364 Hamap MF_00323 Ferrochelatase [hemH]. 15 336 36.993 T 13-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 THITH_02010 aca06b0b7d2884421dfad79a1462b01f 364 ProSitePatterns PS00534 Ferrochelatase signature. 205 223 - T 13-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 THITH_02010 aca06b0b7d2884421dfad79a1462b01f 364 SUPERFAMILY SSF53800 15 341 1.21E-105 T 13-10-2018 THITH_02010 aca06b0b7d2884421dfad79a1462b01f 364 Gene3D G3DSA:3.40.50.1400 18 335 1.4E-93 T 13-10-2018 THITH_02010 aca06b0b7d2884421dfad79a1462b01f 364 TIGRFAM TIGR00109 hemH: ferrochelatase 14 336 6.3E-93 T 13-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 THITH_02010 aca06b0b7d2884421dfad79a1462b01f 364 Pfam PF00762 Ferrochelatase 17 335 2.2E-110 T 13-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 THITH_02010 aca06b0b7d2884421dfad79a1462b01f 364 Gene3D G3DSA:3.40.50.1400 179 317 1.4E-93 T 13-10-2018 THITH_17500 37917e137d30028d36447ddce02f024a 559 TIGRFAM TIGR03593 yidC_nterm: membrane protein insertase, YidC/Oxa1 family, N-terminal domain 4 369 5.4E-96 T 13-10-2018 IPR028053 Membrane insertase YidC, N-terminal THITH_17500 37917e137d30028d36447ddce02f024a 559 Gene3D G3DSA:2.70.98.90 75 350 4.7E-77 T 13-10-2018 IPR038221 YidC, periplasmic domain superfamily THITH_17500 37917e137d30028d36447ddce02f024a 559 PRINTS PR00701 60kDa inner membrane protein signature 84 105 5.1E-72 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THITH_17500 37917e137d30028d36447ddce02f024a 559 PRINTS PR00701 60kDa inner membrane protein signature 2 23 5.1E-72 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THITH_17500 37917e137d30028d36447ddce02f024a 559 PRINTS PR00701 60kDa inner membrane protein signature 181 201 5.1E-72 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THITH_17500 37917e137d30028d36447ddce02f024a 559 PRINTS PR00701 60kDa inner membrane protein signature 265 280 5.1E-72 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THITH_17500 37917e137d30028d36447ddce02f024a 559 PRINTS PR00701 60kDa inner membrane protein signature 479 501 5.1E-72 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THITH_17500 37917e137d30028d36447ddce02f024a 559 PRINTS PR00701 60kDa inner membrane protein signature 341 361 5.1E-72 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THITH_17500 37917e137d30028d36447ddce02f024a 559 PRINTS PR00701 60kDa inner membrane protein signature 432 455 5.1E-72 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THITH_17500 37917e137d30028d36447ddce02f024a 559 PRINTS PR00701 60kDa inner membrane protein signature 515 538 5.1E-72 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THITH_17500 37917e137d30028d36447ddce02f024a 559 Pfam PF14849 YidC periplasmic domain 78 360 1.5E-76 T 13-10-2018 IPR038210 Membrane insertase YidC, periplasmic domain THITH_17500 37917e137d30028d36447ddce02f024a 559 PRINTS PR01900 YidC translocation/secretion protein signature 504 528 8.6E-25 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THITH_17500 37917e137d30028d36447ddce02f024a 559 PRINTS PR01900 YidC translocation/secretion protein signature 485 500 8.6E-25 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THITH_17500 37917e137d30028d36447ddce02f024a 559 PRINTS PR01900 YidC translocation/secretion protein signature 356 372 8.6E-25 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THITH_17500 37917e137d30028d36447ddce02f024a 559 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 370 549 7.1E-71 T 13-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_17500 37917e137d30028d36447ddce02f024a 559 Hamap MF_01810 Membrane protein insertase YidC [yidC]. 4 551 23.856 T 13-10-2018 IPR019998 Membrane insertase YidC GO:0016021|GO:0032977 THITH_17500 37917e137d30028d36447ddce02f024a 559 Pfam PF02096 60Kd inner membrane protein 371 549 3.7E-61 T 13-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 THITH_11805 66b11ed47762cdf8ca65755f2fb651eb 765 Gene3D G3DSA:2.130.10.10 261 429 7.2E-8 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 THITH_11805 66b11ed47762cdf8ca65755f2fb651eb 765 Gene3D G3DSA:1.10.3720.10 534 762 1.9E-18 T 13-10-2018 IPR035906 MetI-like superfamily THITH_11805 66b11ed47762cdf8ca65755f2fb651eb 765 SUPERFAMILY SSF161098 459 560 4.14E-6 T 13-10-2018 IPR035906 MetI-like superfamily THITH_11805 66b11ed47762cdf8ca65755f2fb651eb 765 SUPERFAMILY SSF161098 535 750 9.68E-17 T 13-10-2018 IPR035906 MetI-like superfamily THITH_11805 66b11ed47762cdf8ca65755f2fb651eb 765 SUPERFAMILY SSF50998 89 427 4.63E-12 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THITH_11805 66b11ed47762cdf8ca65755f2fb651eb 765 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 483 761 9.2E-10 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THITH_12400 cc3b0fe1c2ba1f84cb614eec2a201433 352 Gene3D G3DSA:1.10.10.60 226 289 1.6E-11 T 13-10-2018 THITH_12400 cc3b0fe1c2ba1f84cb614eec2a201433 352 SUPERFAMILY SSF46689 232 280 7.77E-9 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_12400 cc3b0fe1c2ba1f84cb614eec2a201433 352 SUPERFAMILY SSF46689 283 334 5.08E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_12400 cc3b0fe1c2ba1f84cb614eec2a201433 352 Gene3D G3DSA:3.40.50.880 5 219 1.0E-45 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_12400 cc3b0fe1c2ba1f84cb614eec2a201433 352 Pfam PF12833 Helix-turn-helix domain 253 331 2.5E-25 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THITH_12400 cc3b0fe1c2ba1f84cb614eec2a201433 352 SMART SM00342 247 330 5.6E-29 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THITH_12400 cc3b0fe1c2ba1f84cb614eec2a201433 352 Gene3D G3DSA:1.10.10.2730 290 332 3.9E-15 T 13-10-2018 THITH_12400 cc3b0fe1c2ba1f84cb614eec2a201433 352 Pfam PF01965 DJ-1/PfpI family 54 166 3.0E-9 T 13-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 THITH_12400 cc3b0fe1c2ba1f84cb614eec2a201433 352 SUPERFAMILY SSF52317 7 212 2.62E-32 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_12400 cc3b0fe1c2ba1f84cb614eec2a201433 352 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 284 326 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THITH_12400 cc3b0fe1c2ba1f84cb614eec2a201433 352 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 299 314 1.7E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THITH_12400 cc3b0fe1c2ba1f84cb614eec2a201433 352 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 314 330 1.7E-5 T 13-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 THITH_05625 c3b5f1762186d4c9dfb6aeb2f5e5467a 139 Pfam PF01850 PIN domain 2 128 2.2E-14 T 13-10-2018 IPR002716 PIN domain THITH_05625 c3b5f1762186d4c9dfb6aeb2f5e5467a 139 Gene3D G3DSA:3.40.50.1010 1 138 6.7E-38 T 13-10-2018 THITH_05625 c3b5f1762186d4c9dfb6aeb2f5e5467a 139 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 136 12.978 T 13-10-2018 IPR022907 VapC family GO:0004540 THITH_05625 c3b5f1762186d4c9dfb6aeb2f5e5467a 139 SUPERFAMILY SSF88723 1 137 2.41E-30 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_10760 3119bf00bf0eb5110f0b60b3b59e6a10 403 Gene3D G3DSA:3.40.50.1100 62 392 2.5E-189 T 13-10-2018 THITH_10760 3119bf00bf0eb5110f0b60b3b59e6a10 403 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 15 397 1.4E-192 T 13-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THITH_10760 3119bf00bf0eb5110f0b60b3b59e6a10 403 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 10 399 53.463 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THITH_10760 3119bf00bf0eb5110f0b60b3b59e6a10 403 PIRSF PIRSF001413 2 403 1.5E-163 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THITH_10760 3119bf00bf0eb5110f0b60b3b59e6a10 403 SUPERFAMILY SSF53686 11 396 6.55E-150 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme THITH_10760 3119bf00bf0eb5110f0b60b3b59e6a10 403 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 62 386 1.1E-47 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme THITH_10760 3119bf00bf0eb5110f0b60b3b59e6a10 403 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 89 103 - T 13-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THITH_10760 3119bf00bf0eb5110f0b60b3b59e6a10 403 Gene3D G3DSA:3.40.50.1100 18 214 2.5E-189 T 13-10-2018 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 13 1358 12.432 T 13-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Pfam PF10385 RNA polymerase beta subunit external 1 domain 597 662 4.0E-26 T 13-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Gene3D G3DSA:3.90.1100.10 19 162 8.1E-51 T 13-10-2018 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Gene3D G3DSA:2.40.270.10 1054 1258 6.7E-88 T 13-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Gene3D G3DSA:3.90.1110.10 163 281 1.3E-26 T 13-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 SUPERFAMILY SSF64484 12 1357 0.0 T 13-10-2018 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Pfam PF04565 RNA polymerase Rpb2, domain 3 519 586 1.5E-30 T 13-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Gene3D G3DSA:2.40.50.100 720 794 1.2E-31 T 13-10-2018 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Pfam PF04561 RNA polymerase Rpb2, domain 2 158 225 1.2E-5 T 13-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Pfam PF04561 RNA polymerase Rpb2, domain 2 362 460 9.8E-15 T 13-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Gene3D G3DSA:2.40.50.150 839 956 1.4E-45 T 13-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Pfam PF00562 RNA polymerase Rpb2, domain 6 723 1280 4.2E-166 T 13-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Gene3D G3DSA:2.40.270.10 796 838 1.1E-7 T 13-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 ProSitePatterns PS01166 RNA polymerases beta chain signature. 1082 1094 - T 13-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Gene3D G3DSA:3.90.1100.10 650 719 4.8E-21 T 13-10-2018 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Gene3D G3DSA:3.90.1100.10 447 633 2.6E-71 T 13-10-2018 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Pfam PF04560 RNA polymerase Rpb2, domain 7 1282 1356 2.0E-25 T 13-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Gene3D G3DSA:3.90.1800.10 1268 1321 5.3E-10 T 13-10-2018 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 8 1355 0.0 T 13-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Gene3D G3DSA:3.90.1110.10 328 446 1.0E-33 T 13-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14325 94b7a0f330b7473ae05fb9e3d440589f 1358 Pfam PF04563 RNA polymerase beta subunit 26 505 8.3E-43 T 13-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_07465 a32498cd37074b718689941f7b0d16c5 548 SUPERFAMILY SSF56219 264 545 8.64E-38 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily THITH_07465 a32498cd37074b718689941f7b0d16c5 548 Gene3D G3DSA:3.60.10.10 264 546 4.6E-28 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily THITH_07465 a32498cd37074b718689941f7b0d16c5 548 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 267 499 1.7E-10 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase THITH_17235 0c8c797d56a92137b8510c5843597c98 358 PRINTS PR00101 Aspartate carbamoyltransferase signature 116 125 8.2E-24 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_17235 0c8c797d56a92137b8510c5843597c98 358 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 99 8.2E-24 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_17235 0c8c797d56a92137b8510c5843597c98 358 PRINTS PR00101 Aspartate carbamoyltransferase signature 170 187 8.2E-24 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_17235 0c8c797d56a92137b8510c5843597c98 358 PRINTS PR00101 Aspartate carbamoyltransferase signature 327 341 8.2E-24 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_17235 0c8c797d56a92137b8510c5843597c98 358 PRINTS PR00101 Aspartate carbamoyltransferase signature 305 310 8.2E-24 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_17235 0c8c797d56a92137b8510c5843597c98 358 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 87 94 - T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THITH_17235 0c8c797d56a92137b8510c5843597c98 358 SUPERFAMILY SSF53671 40 348 6.29E-67 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 THITH_17235 0c8c797d56a92137b8510c5843597c98 358 Gene3D G3DSA:3.40.50.1370 171 333 5.0E-71 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 THITH_17235 0c8c797d56a92137b8510c5843597c98 358 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 44 183 3.9E-37 T 13-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 THITH_17235 0c8c797d56a92137b8510c5843597c98 358 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 87 106 2.3E-20 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THITH_17235 0c8c797d56a92137b8510c5843597c98 358 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 311 334 2.3E-20 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THITH_17235 0c8c797d56a92137b8510c5843597c98 358 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 171 182 2.3E-20 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THITH_17235 0c8c797d56a92137b8510c5843597c98 358 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 301 310 2.3E-20 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THITH_17235 0c8c797d56a92137b8510c5843597c98 358 Gene3D G3DSA:3.40.50.1370 45 343 5.0E-71 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 THITH_17235 0c8c797d56a92137b8510c5843597c98 358 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 200 344 2.1E-7 T 13-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 THITH_15875 9b960297887946873aacea7f95d2ff44 493 SUPERFAMILY SSF56322 14 482 8.37E-160 T 13-10-2018 IPR005801 ADC synthase GO:0009058 THITH_15875 9b960297887946873aacea7f95d2ff44 493 Pfam PF04715 Anthranilate synthase component I, N terminal region 26 169 1.6E-32 T 13-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THITH_15875 9b960297887946873aacea7f95d2ff44 493 PRINTS PR00095 Anthranilate synthase component I signature 321 334 9.0E-25 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THITH_15875 9b960297887946873aacea7f95d2ff44 493 PRINTS PR00095 Anthranilate synthase component I signature 415 429 9.0E-25 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THITH_15875 9b960297887946873aacea7f95d2ff44 493 PRINTS PR00095 Anthranilate synthase component I signature 335 348 9.0E-25 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THITH_15875 9b960297887946873aacea7f95d2ff44 493 PRINTS PR00095 Anthranilate synthase component I signature 430 444 9.0E-25 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THITH_15875 9b960297887946873aacea7f95d2ff44 493 Pfam PF00425 chorismate binding enzyme 221 473 9.0E-100 T 13-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal THITH_15875 9b960297887946873aacea7f95d2ff44 493 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 26 481 9.3E-171 T 13-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THITH_15875 9b960297887946873aacea7f95d2ff44 493 Gene3D G3DSA:3.60.120.10 1 486 3.0E-180 T 13-10-2018 IPR005801 ADC synthase GO:0009058 THITH_14280 c42e6fef7760d8abf8569f740832393f 98 SUPERFAMILY SSF54189 5 93 1.65E-29 T 13-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14280 c42e6fef7760d8abf8569f740832393f 98 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 6 95 21.346 T 13-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 THITH_14280 c42e6fef7760d8abf8569f740832393f 98 Gene3D G3DSA:3.30.70.330 1 96 1.6E-33 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily THITH_14280 c42e6fef7760d8abf8569f740832393f 98 Pfam PF00276 Ribosomal protein L23 7 91 8.6E-32 T 13-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 THITH_12805 6b72ec61a259d1f9178a954b7af880a3 258 SUPERFAMILY SSF56784 5 223 8.0E-46 T 13-10-2018 IPR036412 HAD-like superfamily THITH_12805 6b72ec61a259d1f9178a954b7af880a3 258 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 201 9.8E-23 T 13-10-2018 THITH_12805 6b72ec61a259d1f9178a954b7af880a3 258 Gene3D G3DSA:3.40.50.1000 6 220 1.1E-74 T 13-10-2018 IPR023214 HAD superfamily THITH_12805 6b72ec61a259d1f9178a954b7af880a3 258 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 162 1.4E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_12805 6b72ec61a259d1f9178a954b7af880a3 258 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 4 15 1.4E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_12805 6b72ec61a259d1f9178a954b7af880a3 258 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 191 204 1.4E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_12805 6b72ec61a259d1f9178a954b7af880a3 258 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 164 184 1.4E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_12805 6b72ec61a259d1f9178a954b7af880a3 258 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 112 125 1.4E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_12805 6b72ec61a259d1f9178a954b7af880a3 258 Gene3D G3DSA:1.10.150.240 18 99 1.1E-74 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 THITH_12805 6b72ec61a259d1f9178a954b7af880a3 258 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 84 201 1.9E-15 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_11095 ab225ea25619b676cfd025436c4bb694 186 Gene3D G3DSA:3.90.1570.10 3 183 6.7E-24 T 13-10-2018 THITH_11095 ab225ea25619b676cfd025436c4bb694 186 Pfam PF05685 Putative restriction endonuclease 13 172 3.0E-35 T 13-10-2018 IPR008538 Domain of unknown function DUF820 THITH_11095 ab225ea25619b676cfd025436c4bb694 186 SUPERFAMILY SSF52980 6 161 4.08E-29 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_14130 e35f54fdb161f37de85819f7bb6aeca9 154 SUPERFAMILY SSF55486 25 150 2.69E-37 T 13-10-2018 THITH_14130 e35f54fdb161f37de85819f7bb6aeca9 154 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 1 148 19.769 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 THITH_14130 e35f54fdb161f37de85819f7bb6aeca9 154 Pfam PF02130 Uncharacterized protein family UPF0054 27 143 4.2E-28 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 THITH_14130 e35f54fdb161f37de85819f7bb6aeca9 154 Gene3D G3DSA:3.40.390.30 1 153 7.6E-41 T 13-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 THITH_14130 e35f54fdb161f37de85819f7bb6aeca9 154 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 144 7.2E-31 T 13-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 THITH_14130 e35f54fdb161f37de85819f7bb6aeca9 154 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 114 124 - T 13-10-2018 IPR020549 Endoribonuclease YbeY, conserved site THITH_09350 08ea1c8faa9eee001b34874e3f444ca6 132 Pfam PF03750 Csm2 Type III-A 27 127 1.4E-19 T 13-10-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A THITH_09350 08ea1c8faa9eee001b34874e3f444ca6 132 TIGRFAM TIGR01870 cas_TM1810_Csm2: CRISPR type III-A/MTUBE-associated protein Csm2 42 127 5.1E-17 T 13-10-2018 IPR010149 CRISPR-associated protein, Csm2 Type III-A THITH_14140 640fa15b4610b50a5f24bad3ba2115ac 457 SMART SM00729 146 366 4.1E-58 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THITH_14140 640fa15b4610b50a5f24bad3ba2115ac 457 Pfam PF01938 TRAM domain 379 439 1.6E-16 T 13-10-2018 IPR002792 TRAM domain THITH_14140 640fa15b4610b50a5f24bad3ba2115ac 457 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 4 436 2.8E-176 T 13-10-2018 THITH_14140 640fa15b4610b50a5f24bad3ba2115ac 457 SUPERFAMILY SSF102114 122 374 1.7E-61 T 13-10-2018 THITH_14140 640fa15b4610b50a5f24bad3ba2115ac 457 Pfam PF04055 Radical SAM superfamily 150 324 2.9E-26 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THITH_14140 640fa15b4610b50a5f24bad3ba2115ac 457 Gene3D G3DSA:3.80.30.20 145 379 9.5E-82 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe THITH_14140 640fa15b4610b50a5f24bad3ba2115ac 457 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 436 1.8E-143 T 13-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 THITH_14140 640fa15b4610b50a5f24bad3ba2115ac 457 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 2 440 73.189 T 13-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 THITH_14140 640fa15b4610b50a5f24bad3ba2115ac 457 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 150 170 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 THITH_14140 640fa15b4610b50a5f24bad3ba2115ac 457 Gene3D G3DSA:3.40.50.12160 2 133 2.3E-30 T 13-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily THITH_14140 640fa15b4610b50a5f24bad3ba2115ac 457 Pfam PF00919 Uncharacterized protein family UPF0004 3 103 1.1E-26 T 13-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 THITH_06945 f2c97657fcdc000900a1a602c40dd484 563 PRINTS PR00419 Adrenodoxin reductase family signature 128 150 4.8E-18 T 13-10-2018 THITH_06945 f2c97657fcdc000900a1a602c40dd484 563 PRINTS PR00419 Adrenodoxin reductase family signature 151 164 4.8E-18 T 13-10-2018 THITH_06945 f2c97657fcdc000900a1a602c40dd484 563 PRINTS PR00419 Adrenodoxin reductase family signature 261 275 4.8E-18 T 13-10-2018 THITH_06945 f2c97657fcdc000900a1a602c40dd484 563 PRINTS PR00419 Adrenodoxin reductase family signature 194 204 4.8E-18 T 13-10-2018 THITH_06945 f2c97657fcdc000900a1a602c40dd484 563 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 129 426 6.0E-23 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THITH_06945 f2c97657fcdc000900a1a602c40dd484 563 SUPERFAMILY SSF51971 129 378 7.89E-43 T 13-10-2018 THITH_06945 f2c97657fcdc000900a1a602c40dd484 563 Gene3D G3DSA:3.30.70.20 489 563 3.6E-8 T 13-10-2018 THITH_06945 f2c97657fcdc000900a1a602c40dd484 563 SUPERFAMILY SSF46548 35 137 1.94E-18 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_06945 f2c97657fcdc000900a1a602c40dd484 563 Gene3D G3DSA:3.50.50.60 127 238 6.1E-26 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_06945 f2c97657fcdc000900a1a602c40dd484 563 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 34 114 1.8E-16 T 13-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 THITH_06945 f2c97657fcdc000900a1a602c40dd484 563 Gene3D G3DSA:3.50.50.60 239 377 1.3E-26 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_06945 f2c97657fcdc000900a1a602c40dd484 563 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 543 554 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_06945 f2c97657fcdc000900a1a602c40dd484 563 SUPERFAMILY SSF54862 23 562 5.86E-12 T 13-10-2018 THITH_06945 f2c97657fcdc000900a1a602c40dd484 563 Pfam PF00037 4Fe-4S binding domain 536 556 6.3E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_06945 f2c97657fcdc000900a1a602c40dd484 563 Gene3D G3DSA:1.10.1060.10 16 121 5.0E-23 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_03625 347e4ef73ed0178d1c6ad4268bd5b786 562 SUPERFAMILY SSF52518 1 180 4.36E-63 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold THITH_03625 347e4ef73ed0178d1c6ad4268bd5b786 562 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 537 1.9E-48 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THITH_03625 347e4ef73ed0178d1c6ad4268bd5b786 562 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 191 325 4.3E-44 T 13-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 THITH_03625 347e4ef73ed0178d1c6ad4268bd5b786 562 Gene3D G3DSA:3.40.50.970 359 560 3.5E-65 T 13-10-2018 THITH_03625 347e4ef73ed0178d1c6ad4268bd5b786 562 SUPERFAMILY SSF52467 184 357 5.39E-65 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily THITH_03625 347e4ef73ed0178d1c6ad4268bd5b786 562 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 2 166 2.1E-57 T 13-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 THITH_03625 347e4ef73ed0178d1c6ad4268bd5b786 562 Gene3D G3DSA:3.40.50.970 1 183 7.9E-71 T 13-10-2018 THITH_03625 347e4ef73ed0178d1c6ad4268bd5b786 562 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 2 561 2.1E-260 T 13-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 THITH_03625 347e4ef73ed0178d1c6ad4268bd5b786 562 Gene3D G3DSA:3.40.50.1220 187 355 1.7E-61 T 13-10-2018 THITH_03625 347e4ef73ed0178d1c6ad4268bd5b786 562 SUPERFAMILY SSF52518 367 560 1.47E-68 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold THITH_00210 0f562331c6144f64b9cd3ffaa87ebb6b 238 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_00210 0f562331c6144f64b9cd3ffaa87ebb6b 238 Gene3D G3DSA:3.40.50.300 13 237 3.0E-74 T 13-10-2018 THITH_00210 0f562331c6144f64b9cd3ffaa87ebb6b 238 Pfam PF00005 ABC transporter 38 187 4.9E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_00210 0f562331c6144f64b9cd3ffaa87ebb6b 238 SUPERFAMILY SSF52540 15 234 1.52E-67 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00210 0f562331c6144f64b9cd3ffaa87ebb6b 238 SMART SM00382 46 235 1.3E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_08665 6448de5b9d73ba20a9e56a52e5e05a4b 420 SUPERFAMILY SSF53300 292 399 1.76E-6 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily THITH_08665 6448de5b9d73ba20a9e56a52e5e05a4b 420 Pfam PF13203 Putative metallopeptidase domain 8 279 4.8E-45 T 13-10-2018 IPR025154 Putative metallopeptidase domain THITH_08665 6448de5b9d73ba20a9e56a52e5e05a4b 420 Pfam PF09967 VWA-like domain (DUF2201) 295 419 4.9E-25 T 13-10-2018 IPR018698 VWA-like domain THITH_13505 bd2b8045c9342aebe6b72a73e84f4b7b 322 SUPERFAMILY SSF47823 29 124 1.82E-30 T 13-10-2018 THITH_13505 bd2b8045c9342aebe6b72a73e84f4b7b 322 Gene3D G3DSA:1.10.150.130 30 124 2.3E-19 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal THITH_13505 bd2b8045c9342aebe6b72a73e84f4b7b 322 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 34 321 5.4E-112 T 13-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 THITH_13505 bd2b8045c9342aebe6b72a73e84f4b7b 322 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 28 322 58.914 T 13-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 THITH_13505 bd2b8045c9342aebe6b72a73e84f4b7b 322 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 32 114 1.9E-19 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THITH_13505 bd2b8045c9342aebe6b72a73e84f4b7b 322 Gene3D G3DSA:1.10.443.10 136 316 2.2E-68 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 THITH_13505 bd2b8045c9342aebe6b72a73e84f4b7b 322 SUPERFAMILY SSF56349 140 320 1.0E-55 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THITH_13505 bd2b8045c9342aebe6b72a73e84f4b7b 322 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 30 322 57.488 T 13-10-2018 IPR023009 Tyrosine recombinase XerC/XerD THITH_13505 bd2b8045c9342aebe6b72a73e84f4b7b 322 Pfam PF00589 Phage integrase family 139 307 1.3E-49 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THITH_01985 f9c2279c8f9e06b6d913dd504fda956e 730 SUPERFAMILY SSF161219 434 482 4.05E-5 T 13-10-2018 IPR037274 Zinc finger, CHY-type superfamily GO:0008270 Reactome: R-HSA-110320|Reactome: R-HSA-983168 THITH_01985 f9c2279c8f9e06b6d913dd504fda956e 730 Gene3D G3DSA:1.10.8.630 5 113 2.6E-31 T 13-10-2018 THITH_01985 f9c2279c8f9e06b6d913dd504fda956e 730 Pfam PF00270 DEAD/DEAH box helicase 201 367 9.5E-13 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THITH_01985 f9c2279c8f9e06b6d913dd504fda956e 730 Hamap MF_00983 Probable primosomal protein N' [priA]. 9 729 23.733 T 13-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 THITH_01985 f9c2279c8f9e06b6d913dd504fda956e 730 SMART SM00487 196 396 3.2E-23 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_01985 f9c2279c8f9e06b6d913dd504fda956e 730 SUPERFAMILY SSF52540 197 382 1.12E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01985 f9c2279c8f9e06b6d913dd504fda956e 730 Gene3D G3DSA:3.40.50.300 191 379 2.8E-70 T 13-10-2018 THITH_01985 f9c2279c8f9e06b6d913dd504fda956e 730 SMART SM00490 492 589 3.3E-6 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_01985 f9c2279c8f9e06b6d913dd504fda956e 730 Pfam PF00271 Helicase conserved C-terminal domain 523 589 1.1E-4 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_01985 f9c2279c8f9e06b6d913dd504fda956e 730 TIGRFAM TIGR00595 priA: primosomal protein N' 222 727 3.2E-168 T 13-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 THITH_01985 f9c2279c8f9e06b6d913dd504fda956e 730 SUPERFAMILY SSF52540 477 611 1.57E-19 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_12430 f3a2139d6bd49de211c8361164a697e6 775 Gene3D G3DSA:3.20.20.210 388 755 0.0 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 THITH_12430 f3a2139d6bd49de211c8361164a697e6 775 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 431 752 2.8E-149 T 13-10-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 THITH_12430 f3a2139d6bd49de211c8361164a697e6 775 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 313 1.8E-108 T 13-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 THITH_12430 f3a2139d6bd49de211c8361164a697e6 775 Hamap MF_00172 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase [metE]. 2 757 35.977 T 13-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 THITH_12430 f3a2139d6bd49de211c8361164a697e6 775 SUPERFAMILY SSF51726 5 391 2.88E-105 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 THITH_12430 f3a2139d6bd49de211c8361164a697e6 775 Gene3D G3DSA:3.20.20.210 6 523 0.0 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 THITH_12430 f3a2139d6bd49de211c8361164a697e6 775 TIGRFAM TIGR01371 met_syn_B12ind: 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 7 756 0.0 T 13-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 THITH_12430 f3a2139d6bd49de211c8361164a697e6 775 SUPERFAMILY SSF51726 395 755 1.03E-115 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 THITH_12430 f3a2139d6bd49de211c8361164a697e6 775 PIRSF PIRSF000382 1 762 0.0 T 13-10-2018 IPR006276 Cobalamin-independent methionine synthase GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 THITH_07745 e1b60cf5a90983c350dd3cf59567ab53 468 SUPERFAMILY SSF54637 10 148 1.76E-39 T 13-10-2018 IPR029069 HotDog domain superfamily THITH_07745 e1b60cf5a90983c350dd3cf59567ab53 468 Gene3D G3DSA:3.10.129.10 6 161 2.4E-47 T 13-10-2018 THITH_07745 e1b60cf5a90983c350dd3cf59567ab53 468 Pfam PF01515 Phosphate acetyl/butaryl transferase 213 455 3.5E-46 T 13-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 THITH_07745 e1b60cf5a90983c350dd3cf59567ab53 468 SUPERFAMILY SSF53659 168 459 3.82E-65 T 13-10-2018 THITH_07745 e1b60cf5a90983c350dd3cf59567ab53 468 PRINTS PR01483 Fatty acid synthase signature 52 73 9.6E-5 T 13-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 THITH_07745 e1b60cf5a90983c350dd3cf59567ab53 468 PRINTS PR01483 Fatty acid synthase signature 30 52 9.6E-5 T 13-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 THITH_07745 e1b60cf5a90983c350dd3cf59567ab53 468 Gene3D G3DSA:3.40.718.10 164 461 1.1E-96 T 13-10-2018 THITH_07745 e1b60cf5a90983c350dd3cf59567ab53 468 Pfam PF01575 MaoC like domain 23 119 8.4E-22 T 13-10-2018 IPR002539 MaoC-like dehydratase domain THITH_07935 02377f2bc9ed3477686b64229a0a62e4 360 Pfam PF00266 Aminotransferase class-V 4 348 1.6E-56 T 13-10-2018 IPR000192 Aminotransferase class V domain THITH_07935 02377f2bc9ed3477686b64229a0a62e4 360 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 359 51.531 T 13-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 THITH_07935 02377f2bc9ed3477686b64229a0a62e4 360 Gene3D G3DSA:3.40.640.10 17 250 4.3E-94 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_07935 02377f2bc9ed3477686b64229a0a62e4 360 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 187 206 - T 13-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site THITH_07935 02377f2bc9ed3477686b64229a0a62e4 360 PIRSF PIRSF000525 1 360 9.5E-154 T 13-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 THITH_07935 02377f2bc9ed3477686b64229a0a62e4 360 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 4 359 7.7E-158 T 13-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 THITH_07935 02377f2bc9ed3477686b64229a0a62e4 360 SUPERFAMILY SSF53383 1 358 3.77E-120 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_07935 02377f2bc9ed3477686b64229a0a62e4 360 Gene3D G3DSA:3.90.1150.10 251 360 2.2E-44 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_14165 8b04f467619dd70fa67136f7259ab5cf 330 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 255 327 9.0E-32 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14165 8b04f467619dd70fa67136f7259ab5cf 330 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 5 316 35.332 T 13-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14165 8b04f467619dd70fa67136f7259ab5cf 330 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 251 307 1.4E-22 T 13-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14165 8b04f467619dd70fa67136f7259ab5cf 330 SUPERFAMILY SSF56553 53 177 1.18E-40 T 13-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14165 8b04f467619dd70fa67136f7259ab5cf 330 Gene3D G3DSA:1.10.150.20 245 328 3.6E-35 T 13-10-2018 THITH_14165 8b04f467619dd70fa67136f7259ab5cf 330 SUPERFAMILY SSF47789 250 323 2.35E-25 T 13-10-2018 THITH_14165 8b04f467619dd70fa67136f7259ab5cf 330 SUPERFAMILY SSF55257 6 232 1.08E-29 T 13-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14165 8b04f467619dd70fa67136f7259ab5cf 330 Gene3D G3DSA:3.30.1360.10 17 226 4.5E-82 T 13-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14165 8b04f467619dd70fa67136f7259ab5cf 330 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 29 226 1.3E-22 T 13-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14165 8b04f467619dd70fa67136f7259ab5cf 330 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 24 315 1.0E-106 T 13-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14165 8b04f467619dd70fa67136f7259ab5cf 330 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 62 154 2.1E-24 T 13-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14165 8b04f467619dd70fa67136f7259ab5cf 330 SMART SM00662 23 233 5.5E-91 T 13-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14165 8b04f467619dd70fa67136f7259ab5cf 330 Gene3D G3DSA:2.170.120.12 53 176 4.5E-82 T 13-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_15740 43b358f2edb4d7b6dac652ce4797af5a 284 Gene3D G3DSA:3.40.50.150 58 283 1.4E-63 T 13-10-2018 THITH_15740 43b358f2edb4d7b6dac652ce4797af5a 284 Pfam PF17284 Spermidine synthase tetramerisation domain 7 57 1.8E-14 T 13-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 THITH_15740 43b358f2edb4d7b6dac652ce4797af5a 284 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 82 95 - T 13-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 THITH_15740 43b358f2edb4d7b6dac652ce4797af5a 284 Pfam PF01564 Spermine/spermidine synthase domain 62 242 2.1E-48 T 13-10-2018 THITH_15740 43b358f2edb4d7b6dac652ce4797af5a 284 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 6 283 36.073 T 13-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 THITH_15740 43b358f2edb4d7b6dac652ce4797af5a 284 SUPERFAMILY SSF53335 6 282 9.83E-76 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_15740 43b358f2edb4d7b6dac652ce4797af5a 284 Gene3D G3DSA:2.30.140.10 3 57 5.2E-23 T 13-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 THITH_15740 43b358f2edb4d7b6dac652ce4797af5a 284 TIGRFAM TIGR00417 speE: spermidine synthase 7 277 1.8E-81 T 13-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 THITH_00950 4bb90f3daedcb3de57ea1f30a4fe954b 315 SUPERFAMILY SSF52374 18 175 1.16E-30 T 13-10-2018 THITH_00950 4bb90f3daedcb3de57ea1f30a4fe954b 315 Gene3D G3DSA:3.40.50.620 9 185 6.3E-55 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_00950 4bb90f3daedcb3de57ea1f30a4fe954b 315 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 306 1.4E-77 T 13-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 THITH_00950 4bb90f3daedcb3de57ea1f30a4fe954b 315 SUPERFAMILY SSF82114 173 310 4.8E-41 T 13-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 THITH_00950 4bb90f3daedcb3de57ea1f30a4fe954b 315 SMART SM00904 183 307 8.1E-55 T 13-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 THITH_00950 4bb90f3daedcb3de57ea1f30a4fe954b 315 Gene3D G3DSA:2.40.30.30 186 314 1.3E-37 T 13-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 THITH_00950 4bb90f3daedcb3de57ea1f30a4fe954b 315 Pfam PF06574 FAD synthetase 15 167 5.2E-48 T 13-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 THITH_00950 4bb90f3daedcb3de57ea1f30a4fe954b 315 Pfam PF01687 Riboflavin kinase 184 306 2.9E-33 T 13-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 THITH_00950 4bb90f3daedcb3de57ea1f30a4fe954b 315 PIRSF PIRSF004491 2 313 5.6E-93 T 13-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 THITH_16215 af294f667051efc9103dce1840614052 431 SUPERFAMILY SSF51905 146 282 6.34E-36 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_16215 af294f667051efc9103dce1840614052 431 Gene3D G3DSA:3.90.760.10 355 431 1.1E-19 T 13-10-2018 IPR037092 Flavocytochrome c sulphide dehydrogenase, flavin-binding domain superfamily GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 THITH_16215 af294f667051efc9103dce1840614052 431 SUPERFAMILY SSF55424 356 431 2.11E-14 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THITH_16215 af294f667051efc9103dce1840614052 431 Pfam PF09242 Flavocytochrome c sulphide dehydrogenase, flavin-binding 357 430 2.8E-21 T 13-10-2018 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 THITH_16215 af294f667051efc9103dce1840614052 431 SUPERFAMILY SSF51905 33 159 5.19E-26 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_16215 af294f667051efc9103dce1840614052 431 Gene3D G3DSA:3.50.50.60 35 343 6.6E-104 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_16215 af294f667051efc9103dce1840614052 431 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 35 137 4.0E-9 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THITH_16215 af294f667051efc9103dce1840614052 431 Gene3D G3DSA:3.50.50.60 148 282 6.6E-104 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_09575 1394ea4e240fa5d6dfa2b2c742873ec4 273 SUPERFAMILY SSF54534 139 230 1.44E-28 T 13-10-2018 THITH_09575 1394ea4e240fa5d6dfa2b2c742873ec4 273 Gene3D G3DSA:3.10.50.40 131 254 2.8E-31 T 13-10-2018 THITH_09575 1394ea4e240fa5d6dfa2b2c742873ec4 273 Pfam PF13616 PPIC-type PPIASE domain 139 227 3.7E-19 T 13-10-2018 THITH_09575 1394ea4e240fa5d6dfa2b2c742873ec4 273 SUPERFAMILY SSF109998 36 167 3.92E-15 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily THITH_09575 1394ea4e240fa5d6dfa2b2c742873ec4 273 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 166 186 - T 13-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 THITH_13265 5509fd6961ff9f966393848113872322 147 Pfam PF00578 AhpC/TSA family 13 71 4.1E-5 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THITH_13265 5509fd6961ff9f966393848113872322 147 SUPERFAMILY SSF52833 12 127 1.61E-16 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_13265 5509fd6961ff9f966393848113872322 147 Gene3D G3DSA:3.40.30.10 7 134 2.7E-13 T 13-10-2018 THITH_03090 327f79d52dad86678c36063ebfbaba2d 153 Pfam PF06841 T4-like virus tail tube protein gp19 12 151 2.6E-30 T 13-10-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 THITH_03090 327f79d52dad86678c36063ebfbaba2d 153 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 9 151 9.8E-26 T 13-10-2018 IPR011747 Conserved hypothetical protein CHP02241 THITH_17200 a8c9488e7428e952f857b3e85fe97d31 215 SUPERFAMILY SSF46894 144 213 6.8E-19 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THITH_17200 a8c9488e7428e952f857b3e85fe97d31 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 3.8E-10 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_17200 a8c9488e7428e952f857b3e85fe97d31 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 3.8E-10 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_17200 a8c9488e7428e952f857b3e85fe97d31 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 3.8E-10 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_17200 a8c9488e7428e952f857b3e85fe97d31 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_17200 a8c9488e7428e952f857b3e85fe97d31 215 Gene3D G3DSA:3.40.50.12740 7 213 3.6E-58 T 13-10-2018 THITH_17200 a8c9488e7428e952f857b3e85fe97d31 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 1.2E-15 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_17200 a8c9488e7428e952f857b3e85fe97d31 215 Pfam PF00072 Response regulator receiver domain 9 121 1.9E-23 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_17200 a8c9488e7428e952f857b3e85fe97d31 215 SMART SM00448 7 120 4.7E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_17200 a8c9488e7428e952f857b3e85fe97d31 215 SUPERFAMILY SSF52172 6 135 1.31E-30 T 13-10-2018 IPR011006 CheY-like superfamily THITH_17200 a8c9488e7428e952f857b3e85fe97d31 215 SMART SM00421 150 207 4.7E-19 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_12810 81b7f1a15d69f3b22ee63c8aaf0fbc68 150 Gene3D G3DSA:1.20.120.910 20 150 1.9E-40 T 13-10-2018 THITH_12810 81b7f1a15d69f3b22ee63c8aaf0fbc68 150 PRINTS PR00618 DksA/TraR zinc finger signature 114 125 4.0E-5 T 13-10-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria THITH_12810 81b7f1a15d69f3b22ee63c8aaf0fbc68 150 PRINTS PR00618 DksA/TraR zinc finger signature 126 138 4.0E-5 T 13-10-2018 IPR020460 Zinc finger, DksA/TraR C4-type, bacteria THITH_12810 81b7f1a15d69f3b22ee63c8aaf0fbc68 150 Hamap MF_00926 RNA polymerase-binding transcription factor DksA [dksA]. 28 150 30.525 T 13-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 THITH_12810 81b7f1a15d69f3b22ee63c8aaf0fbc68 150 SUPERFAMILY SSF109635 14 110 7.45E-35 T 13-10-2018 IPR037187 DksA, N-terminal domain superfamily THITH_12810 81b7f1a15d69f3b22ee63c8aaf0fbc68 150 SUPERFAMILY SSF57716 111 148 1.37E-10 T 13-10-2018 THITH_12810 81b7f1a15d69f3b22ee63c8aaf0fbc68 150 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 109 143 2.5E-12 T 13-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 THITH_12810 81b7f1a15d69f3b22ee63c8aaf0fbc68 150 TIGRFAM TIGR02420 dksA: RNA polymerase-binding protein DksA 32 140 7.2E-51 T 13-10-2018 IPR012784 RNA polymerase-binding transcription factor DksA GO:0008270 THITH_12810 81b7f1a15d69f3b22ee63c8aaf0fbc68 150 ProSitePatterns PS01102 Prokaryotic dksA C4-type zinc finger. 114 138 - T 13-10-2018 IPR020458 Zinc finger, DksA/TraR C4-type conserved site THITH_07005 bf628a244df5f4895eb4c330d7d251b5 630 Gene3D G3DSA:3.30.300.30 488 625 3.4E-6 T 13-10-2018 THITH_07005 bf628a244df5f4895eb4c330d7d251b5 630 Gene3D G3DSA:3.40.50.12780 33 335 6.1E-56 T 13-10-2018 THITH_07005 bf628a244df5f4895eb4c330d7d251b5 630 Gene3D G3DSA:3.40.50.12780 336 482 1.3E-36 T 13-10-2018 THITH_07005 bf628a244df5f4895eb4c330d7d251b5 630 Pfam PF00501 AMP-binding enzyme 44 492 1.9E-93 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 THITH_07005 bf628a244df5f4895eb4c330d7d251b5 630 SUPERFAMILY SSF56801 32 628 1.07E-119 T 13-10-2018 THITH_07005 bf628a244df5f4895eb4c330d7d251b5 630 ProSitePatterns PS00455 Putative AMP-binding domain signature. 209 220 - T 13-10-2018 IPR020845 AMP-binding, conserved site THITH_07625 53eb63d66ca3bd4c79758558ed809ad6 563 Gene3D G3DSA:2.40.240.10 349 467 1.8E-79 T 13-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THITH_07625 53eb63d66ca3bd4c79758558ed809ad6 563 SUPERFAMILY SSF50715 341 551 3.03E-71 T 13-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THITH_07625 53eb63d66ca3bd4c79758558ed809ad6 563 Gene3D G3DSA:3.90.800.10 102 210 9.6E-94 T 13-10-2018 THITH_07625 53eb63d66ca3bd4c79758558ed809ad6 563 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 341 533 4.7E-60 T 13-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THITH_07625 53eb63d66ca3bd4c79758558ed809ad6 563 Gene3D G3DSA:2.40.240.10 341 550 1.8E-79 T 13-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 THITH_07625 53eb63d66ca3bd4c79758558ed809ad6 563 Gene3D G3DSA:3.40.50.620 30 249 9.6E-94 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_07625 53eb63d66ca3bd4c79758558ed809ad6 563 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 36 47 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_07625 53eb63d66ca3bd4c79758558ed809ad6 563 SUPERFAMILY SSF52374 30 347 5.91E-87 T 13-10-2018 THITH_07625 53eb63d66ca3bd4c79758558ed809ad6 563 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 30 321 1.0E-95 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 THITH_07625 53eb63d66ca3bd4c79758558ed809ad6 563 PRINTS PR00987 Glutamyl-tRNA synthetase signature 33 45 1.8E-9 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THITH_07625 53eb63d66ca3bd4c79758558ed809ad6 563 PRINTS PR00987 Glutamyl-tRNA synthetase signature 62 75 1.8E-9 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THITH_07625 53eb63d66ca3bd4c79758558ed809ad6 563 PRINTS PR00987 Glutamyl-tRNA synthetase signature 211 221 1.8E-9 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THITH_07625 53eb63d66ca3bd4c79758558ed809ad6 563 PRINTS PR00987 Glutamyl-tRNA synthetase signature 47 58 1.8E-9 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THITH_07625 53eb63d66ca3bd4c79758558ed809ad6 563 Hamap MF_00126 Glutamine--tRNA ligase [glnS]. 1 553 50.214 T 13-10-2018 IPR022861 Glutamine-tRNA ligase, bacterial GO:0004819 KEGG: 00970+6.1.1.18 THITH_07625 53eb63d66ca3bd4c79758558ed809ad6 563 Gene3D G3DSA:1.10.1160.10 262 340 1.6E-30 T 13-10-2018 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily GO:0005524 THITH_07625 53eb63d66ca3bd4c79758558ed809ad6 563 TIGRFAM TIGR00440 glnS: glutamine--tRNA ligase 30 555 1.9E-207 T 13-10-2018 IPR004514 Glutamine-tRNA synthetase GO:0000166|GO:0004819|GO:0005524|GO:0005737|GO:0006425 KEGG: 00970+6.1.1.18|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 THITH_08605 24c565d22d51c1b74ce9ebb22d4bf1b7 395 Gene3D G3DSA:3.90.1150.10 27 388 2.6E-132 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_08605 24c565d22d51c1b74ce9ebb22d4bf1b7 395 Pfam PF00155 Aminotransferase class I and II 33 388 6.7E-77 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THITH_08605 24c565d22d51c1b74ce9ebb22d4bf1b7 395 SUPERFAMILY SSF53383 4 392 1.25E-115 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_08605 24c565d22d51c1b74ce9ebb22d4bf1b7 395 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 237 250 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 THITH_08605 24c565d22d51c1b74ce9ebb22d4bf1b7 395 Gene3D G3DSA:3.40.640.10 64 287 2.6E-132 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_03545 fcb4b604db5a5f71c07c757cf84f887c 75 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 2 73 22.166 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03545 fcb4b604db5a5f71c07c757cf84f887c 75 ProSitePatterns PS00057 Ribosomal protein S18 signature. 21 44 - T 13-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03545 fcb4b604db5a5f71c07c757cf84f887c 75 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 21 71 5.0E-20 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03545 fcb4b604db5a5f71c07c757cf84f887c 75 PRINTS PR00974 Ribosomal protein S18 family signature 28 38 6.9E-19 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03545 fcb4b604db5a5f71c07c757cf84f887c 75 PRINTS PR00974 Ribosomal protein S18 family signature 38 45 6.9E-19 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03545 fcb4b604db5a5f71c07c757cf84f887c 75 PRINTS PR00974 Ribosomal protein S18 family signature 60 70 6.9E-19 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03545 fcb4b604db5a5f71c07c757cf84f887c 75 PRINTS PR00974 Ribosomal protein S18 family signature 46 60 6.9E-19 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03545 fcb4b604db5a5f71c07c757cf84f887c 75 SUPERFAMILY SSF46911 4 74 7.85E-30 T 13-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03545 fcb4b604db5a5f71c07c757cf84f887c 75 Pfam PF01084 Ribosomal protein S18 18 68 3.0E-26 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03545 fcb4b604db5a5f71c07c757cf84f887c 75 Gene3D G3DSA:4.10.640.10 1 75 3.5E-29 T 13-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03545 fcb4b604db5a5f71c07c757cf84f887c 75 TIGRFAM TIGR00165 S18: ribosomal protein bS18 5 72 4.5E-36 T 13-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_09980 b9328821dabe5659e1651693099ac377 193 SUPERFAMILY SSF54719 83 191 5.24E-45 T 13-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THITH_09980 b9328821dabe5659e1651693099ac377 193 Gene3D G3DSA:1.10.287.990 20 83 1.8E-24 T 13-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THITH_09980 b9328821dabe5659e1651693099ac377 193 Gene3D G3DSA:2.40.500.20 84 193 3.7E-45 T 13-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THITH_09980 b9328821dabe5659e1651693099ac377 193 PRINTS PR01703 Manganese superoxide dismutase signature 156 168 1.8E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THITH_09980 b9328821dabe5659e1651693099ac377 193 PRINTS PR01703 Manganese superoxide dismutase signature 66 79 1.8E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THITH_09980 b9328821dabe5659e1651693099ac377 193 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 1.8E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THITH_09980 b9328821dabe5659e1651693099ac377 193 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 1.8E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THITH_09980 b9328821dabe5659e1651693099ac377 193 PRINTS PR01703 Manganese superoxide dismutase signature 119 127 1.8E-21 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THITH_09980 b9328821dabe5659e1651693099ac377 193 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 82 3.2E-33 T 13-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THITH_09980 b9328821dabe5659e1651693099ac377 193 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 158 165 - T 13-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THITH_09980 b9328821dabe5659e1651693099ac377 193 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 90 190 5.1E-41 T 13-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THITH_09980 b9328821dabe5659e1651693099ac377 193 SUPERFAMILY SSF46609 1 88 1.96E-33 T 13-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THITH_09980 b9328821dabe5659e1651693099ac377 193 PIRSF PIRSF000349 1 193 1.1E-86 T 13-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 THITH_01905 522ea69fe82be342d8f30030d552a956 356 PIRSF PIRSF015268 7 349 1.8E-138 T 13-10-2018 IPR011204 Virulence protein RhuM-like THITH_01905 522ea69fe82be342d8f30030d552a956 356 Pfam PF13310 Virulence protein RhuM family 73 325 3.0E-108 T 13-10-2018 IPR011204 Virulence protein RhuM-like THITH_09915 95228814c7abd60d2996af67c7b145aa 175 PIRSF PIRSF006181 4 162 1.4E-41 T 13-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC THITH_09915 95228814c7abd60d2996af67c7b145aa 175 Gene3D G3DSA:3.90.960.10 3 161 4.5E-40 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 THITH_09915 95228814c7abd60d2996af67c7b145aa 175 Pfam PF04073 Aminoacyl-tRNA editing domain 36 149 3.4E-24 T 13-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THITH_09915 95228814c7abd60d2996af67c7b145aa 175 SUPERFAMILY SSF55826 10 158 3.27E-36 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 THITH_00325 8ea3045be98dc544b3e846e82629e52c 104 ProDom PD012578 PLASMID TOXIN CCDB CYTOTOXIC LETB POST-SEGREGATION SYSTEM CCDB-LIKE GYRASE FUSED-CCDB 20 103 6.0E-11 T 13-10-2018 IPR002712 Toxin CcdB GO:0006276|GO:0008657 THITH_00325 8ea3045be98dc544b3e846e82629e52c 104 SUPERFAMILY SSF50118 2 104 2.16E-25 T 13-10-2018 THITH_00325 8ea3045be98dc544b3e846e82629e52c 104 Pfam PF01845 CcdB protein 3 103 6.8E-30 T 13-10-2018 IPR002712 Toxin CcdB GO:0006276|GO:0008657 THITH_00325 8ea3045be98dc544b3e846e82629e52c 104 Gene3D G3DSA:2.30.30.110 1 104 1.7E-31 T 13-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THITH_00150 60025abc6243ea4c95699518ec9c4cf5 516 Pfam PF01676 Metalloenzyme superfamily 11 497 4.1E-65 T 13-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 THITH_00150 60025abc6243ea4c95699518ec9c4cf5 516 Gene3D G3DSA:3.40.1450.10 83 309 2.0E-199 T 13-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_00150 60025abc6243ea4c95699518ec9c4cf5 516 SUPERFAMILY SSF53649 9 508 1.1E-66 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 THITH_00150 60025abc6243ea4c95699518ec9c4cf5 516 Gene3D G3DSA:3.40.720.10 11 508 2.0E-199 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 THITH_00150 60025abc6243ea4c95699518ec9c4cf5 516 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 10 509 44.055 T 13-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_00150 60025abc6243ea4c95699518ec9c4cf5 516 SUPERFAMILY SSF64158 83 307 4.97E-75 T 13-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_00150 60025abc6243ea4c95699518ec9c4cf5 516 PIRSF PIRSF001492 5 511 3.7E-185 T 13-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_00150 60025abc6243ea4c95699518ec9c4cf5 516 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 11 508 1.5E-189 T 13-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_00150 60025abc6243ea4c95699518ec9c4cf5 516 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 88 296 2.6E-72 T 13-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 THITH_13635 eeefa6eb0432df81662766618c6c58dc 173 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 9 139 1.7E-35 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THITH_13635 eeefa6eb0432df81662766618c6c58dc 173 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 94 105 - T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THITH_13635 eeefa6eb0432df81662766618c6c58dc 173 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 8 139 1.8E-42 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THITH_13635 eeefa6eb0432df81662766618c6c58dc 173 SUPERFAMILY SSF55083 8 148 1.27E-48 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THITH_13635 eeefa6eb0432df81662766618c6c58dc 173 Gene3D G3DSA:3.30.70.560 6 161 2.6E-52 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THITH_11350 6fc33a551f27054d0b7ee154bc3877b7 675 PIRSF PIRSF006402 1 675 2.2E-199 T 13-10-2018 IPR024705 Spermatogenesis-associated protein 20 THITH_11350 6fc33a551f27054d0b7ee154bc3877b7 675 Gene3D G3DSA:3.40.30.10 1 170 7.2E-62 T 13-10-2018 THITH_11350 6fc33a551f27054d0b7ee154bc3877b7 675 Pfam PF03190 Protein of unknown function, DUF255 2 163 2.2E-69 T 13-10-2018 IPR004879 Domain of unknown function DUF255 THITH_11350 6fc33a551f27054d0b7ee154bc3877b7 675 SUPERFAMILY SSF48208 185 536 7.94E-62 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 THITH_11350 6fc33a551f27054d0b7ee154bc3877b7 675 SUPERFAMILY SSF52833 2 141 1.17E-27 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_04295 68428d0bbfdd4ad8605a0b07ed9e983c 494 SUPERFAMILY SSF56801 2 489 2.35E-113 T 13-10-2018 THITH_04295 68428d0bbfdd4ad8605a0b07ed9e983c 494 Gene3D G3DSA:3.30.300.30 397 492 1.5E-24 T 13-10-2018 THITH_04295 68428d0bbfdd4ad8605a0b07ed9e983c 494 Pfam PF13193 AMP-binding enzyme C-terminal domain 407 480 3.9E-18 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain THITH_04295 68428d0bbfdd4ad8605a0b07ed9e983c 494 Pfam PF00501 AMP-binding enzyme 8 396 1.7E-64 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 THITH_04295 68428d0bbfdd4ad8605a0b07ed9e983c 494 Gene3D G3DSA:3.40.50.12780 2 391 6.1E-81 T 13-10-2018 THITH_08465 7f6401069505a43822721b96129b57d9 672 Pfam PF00912 Transglycosylase 17 180 2.2E-43 T 13-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_08465 7f6401069505a43822721b96129b57d9 672 SUPERFAMILY SSF56601 164 540 6.47E-71 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like THITH_08465 7f6401069505a43822721b96129b57d9 672 SUPERFAMILY SSF53955 2 215 1.04E-56 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily THITH_08465 7f6401069505a43822721b96129b57d9 672 Pfam PF06832 Penicillin-Binding Protein C-terminus Family 558 639 1.9E-17 T 13-10-2018 IPR009647 Penicillin-binding, C-terminal KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_08465 7f6401069505a43822721b96129b57d9 672 Gene3D G3DSA:3.40.710.10 211 539 7.2E-59 T 13-10-2018 THITH_08465 7f6401069505a43822721b96129b57d9 672 Pfam PF00905 Penicillin binding protein transpeptidase domain 259 475 1.0E-11 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THITH_08465 7f6401069505a43822721b96129b57d9 672 Gene3D G3DSA:1.10.3810.10 10 205 1.4E-48 T 13-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_08465 7f6401069505a43822721b96129b57d9 672 TIGRFAM TIGR02073 PBP_1c: penicillin-binding protein 1C 1 528 7.0E-182 T 13-10-2018 IPR011815 Penicillin-binding protein 1C GO:0008955|GO:0009252 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_11950 176a69f9eaf3e88dd18c11cbb608aafc 259 Gene3D G3DSA:1.20.910.10 13 255 4.9E-43 T 13-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 THITH_11950 176a69f9eaf3e88dd18c11cbb608aafc 259 SUPERFAMILY SSF48613 111 253 2.67E-10 T 13-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 THITH_11950 176a69f9eaf3e88dd18c11cbb608aafc 259 Pfam PF11251 Protein of unknown function (DUF3050) 19 251 2.9E-86 T 13-10-2018 IPR024423 Protein of unknown function DUF3050 THITH_17510 ba0d98830fbb270070c8b7ecbdf34be9 124 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 67 81 - T 13-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 THITH_17510 ba0d98830fbb270070c8b7ecbdf34be9 124 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 15 122 16.433 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 THITH_17510 ba0d98830fbb270070c8b7ecbdf34be9 124 Gene3D G3DSA:3.30.230.10 12 124 3.6E-33 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THITH_17510 ba0d98830fbb270070c8b7ecbdf34be9 124 Pfam PF00825 Ribonuclease P 15 123 4.1E-27 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 THITH_17510 ba0d98830fbb270070c8b7ecbdf34be9 124 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 27 109 5.0E-9 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 THITH_17510 ba0d98830fbb270070c8b7ecbdf34be9 124 SUPERFAMILY SSF54211 15 122 5.56E-24 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_17510 ba0d98830fbb270070c8b7ecbdf34be9 124 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 15 123 1.1E-21 T 13-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 THITH_09175 e1b9a95efe03fe30913aaa8316e19a4e 299 SUPERFAMILY SSF53474 33 299 3.49E-32 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_09175 e1b9a95efe03fe30913aaa8316e19a4e 299 Pfam PF12697 Alpha/beta hydrolase family 53 295 1.2E-10 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_09175 e1b9a95efe03fe30913aaa8316e19a4e 299 Gene3D G3DSA:3.40.50.1820 21 299 4.1E-33 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_05745 cfc4c17ae458162ca27dd1e1840a5284 502 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 213 471 1.0E-70 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 THITH_05745 cfc4c17ae458162ca27dd1e1840a5284 502 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 137 2.6E-28 T 13-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THITH_05745 cfc4c17ae458162ca27dd1e1840a5284 502 SUPERFAMILY SSF48179 270 362 1.87E-23 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THITH_05745 cfc4c17ae458162ca27dd1e1840a5284 502 Gene3D G3DSA:3.40.50.720 271 502 1.4E-55 T 13-10-2018 THITH_05745 cfc4c17ae458162ca27dd1e1840a5284 502 Gene3D G3DSA:3.40.50.720 205 267 2.1E-10 T 13-10-2018 THITH_05745 cfc4c17ae458162ca27dd1e1840a5284 502 Gene3D G3DSA:3.40.50.720 1 145 7.5E-45 T 13-10-2018 THITH_05745 cfc4c17ae458162ca27dd1e1840a5284 502 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 388 489 1.2E-18 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THITH_05745 cfc4c17ae458162ca27dd1e1840a5284 502 PIRSF PIRSF500136 1 144 2.8E-46 T 13-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 THITH_05745 cfc4c17ae458162ca27dd1e1840a5284 502 PIRSF PIRSF500136 204 502 8.9E-93 T 13-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 THITH_05745 cfc4c17ae458162ca27dd1e1840a5284 502 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 272 360 1.8E-22 T 13-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THITH_05745 cfc4c17ae458162ca27dd1e1840a5284 502 SUPERFAMILY SSF52413 372 500 7.98E-27 T 13-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 THITH_05745 cfc4c17ae458162ca27dd1e1840a5284 502 SUPERFAMILY SSF51735 1 139 8.58E-35 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_05745 cfc4c17ae458162ca27dd1e1840a5284 502 PIRSF PIRSF000124 204 502 2.6E-32 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 THITH_05745 cfc4c17ae458162ca27dd1e1840a5284 502 PIRSF PIRSF000124 1 145 2.9E-19 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 THITH_05745 cfc4c17ae458162ca27dd1e1840a5284 502 SMART SM00984 387 489 3.2E-31 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THITH_04430 ab4b7d6477dccd21033f6e3acbba3d22 783 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 77 128 8.5E-10 T 13-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04430 ab4b7d6477dccd21033f6e3acbba3d22 783 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 90 115 1.4E-31 T 13-10-2018 THITH_04430 ab4b7d6477dccd21033f6e3acbba3d22 783 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 118 138 1.4E-31 T 13-10-2018 THITH_04430 ab4b7d6477dccd21033f6e3acbba3d22 783 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 253 279 1.4E-31 T 13-10-2018 THITH_04430 ab4b7d6477dccd21033f6e3acbba3d22 783 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 231 252 1.4E-31 T 13-10-2018 THITH_04430 ab4b7d6477dccd21033f6e3acbba3d22 783 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 321 333 1.4E-31 T 13-10-2018 THITH_04430 ab4b7d6477dccd21033f6e3acbba3d22 783 Pfam PF13244 Domain of unknown function (DUF4040) 622 686 1.4E-17 T 13-10-2018 IPR025383 Domain of unknown function DUF4040 THITH_04430 ab4b7d6477dccd21033f6e3acbba3d22 783 Pfam PF00361 Proton-conducting membrane transporter 141 424 1.5E-60 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_01750 19086c3ee96005ce91ca974d54e63567 263 Pfam PF13444 Acetyltransferase (GNAT) domain 42 146 6.2E-18 T 13-10-2018 THITH_01750 19086c3ee96005ce91ca974d54e63567 263 SUPERFAMILY SSF55729 23 231 1.27E-30 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_01750 19086c3ee96005ce91ca974d54e63567 263 Gene3D G3DSA:3.40.630.30 30 243 1.4E-48 T 13-10-2018 THITH_01750 19086c3ee96005ce91ca974d54e63567 263 TIGRFAM TIGR03694 exosort_acyl: N-acyl amino acid synthase, PEP-CTERM/exosortase system-associated 18 240 1.3E-62 T 13-10-2018 IPR022484 PEP-CTERM/exosortase system-associated acyltransferase, predicted THITH_02600 82c159ad17070d6acedb17cc45513d2e 294 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 287 66.628 T 13-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THITH_02600 82c159ad17070d6acedb17cc45513d2e 294 Gene3D G3DSA:3.20.20.70 2 291 1.8E-114 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_02600 82c159ad17070d6acedb17cc45513d2e 294 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 133 163 - T 13-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 THITH_02600 82c159ad17070d6acedb17cc45513d2e 294 SMART SM01130 1 289 1.4E-146 T 13-10-2018 IPR002220 DapA-like GO:0016829 THITH_02600 82c159ad17070d6acedb17cc45513d2e 294 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 38 55 - T 13-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THITH_02600 82c159ad17070d6acedb17cc45513d2e 294 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 5 276 6.9E-110 T 13-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THITH_02600 82c159ad17070d6acedb17cc45513d2e 294 Pfam PF00701 Dihydrodipicolinate synthetase family 2 276 2.9E-102 T 13-10-2018 IPR002220 DapA-like GO:0016829 THITH_02600 82c159ad17070d6acedb17cc45513d2e 294 PIRSF PIRSF001365 1 292 4.7E-98 T 13-10-2018 IPR002220 DapA-like GO:0016829 THITH_02600 82c159ad17070d6acedb17cc45513d2e 294 SUPERFAMILY SSF51569 1 289 2.09E-106 T 13-10-2018 THITH_02600 82c159ad17070d6acedb17cc45513d2e 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 128 145 5.2E-36 T 13-10-2018 IPR002220 DapA-like GO:0016829 THITH_02600 82c159ad17070d6acedb17cc45513d2e 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 103 119 5.2E-36 T 13-10-2018 IPR002220 DapA-like GO:0016829 THITH_02600 82c159ad17070d6acedb17cc45513d2e 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 35 56 5.2E-36 T 13-10-2018 IPR002220 DapA-like GO:0016829 THITH_02600 82c159ad17070d6acedb17cc45513d2e 294 PRINTS PR00146 Dihydrodipicolinate synthase signature 71 89 5.2E-36 T 13-10-2018 IPR002220 DapA-like GO:0016829 THITH_15955 a940f173524ac178327be24b7ff2b717 391 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 102 8.1E-42 T 13-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_15955 a940f173524ac178327be24b7ff2b717 391 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 387 2.4E-181 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_15955 a940f173524ac178327be24b7ff2b717 391 SUPERFAMILY SSF55973 238 389 4.32E-69 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_15955 a940f173524ac178327be24b7ff2b717 391 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 388 56.938 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_15955 a940f173524ac178327be24b7ff2b717 391 Gene3D G3DSA:3.30.300.10 12 275 4.1E-173 T 13-10-2018 THITH_15955 a940f173524ac178327be24b7ff2b717 391 Gene3D G3DSA:3.30.300.10 103 379 4.1E-173 T 13-10-2018 THITH_15955 a940f173524ac178327be24b7ff2b717 391 Gene3D G3DSA:3.30.300.10 6 238 4.1E-173 T 13-10-2018 THITH_15955 a940f173524ac178327be24b7ff2b717 391 SUPERFAMILY SSF55973 115 237 1.57E-47 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_15955 a940f173524ac178327be24b7ff2b717 391 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 119 129 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_15955 a940f173524ac178327be24b7ff2b717 391 PIRSF PIRSF000497 1 389 2.3E-168 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_15955 a940f173524ac178327be24b7ff2b717 391 Pfam PF02772 S-adenosylmethionine synthetase, central domain 118 236 1.3E-43 T 13-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_15955 a940f173524ac178327be24b7ff2b717 391 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 238 377 1.5E-67 T 13-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_15955 a940f173524ac178327be24b7ff2b717 391 SUPERFAMILY SSF55973 4 111 1.33E-45 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_15955 a940f173524ac178327be24b7ff2b717 391 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 264 272 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_16205 efbad63039a5208147090012ac92922c 553 SUPERFAMILY SSF48695 30 103 4.76E-7 T 13-10-2018 IPR036280 Multiheme cytochrome superfamily THITH_16205 efbad63039a5208147090012ac92922c 553 PIRSF PIRSF000243 32 81 710.0 T 13-10-2018 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 THITH_16205 efbad63039a5208147090012ac92922c 553 PIRSF PIRSF000243 51 110 1600.0 T 13-10-2018 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 THITH_16205 efbad63039a5208147090012ac92922c 553 PIRSF PIRSF000243 78 553 1.2E-96 T 13-10-2018 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 THITH_16205 efbad63039a5208147090012ac92922c 553 SUPERFAMILY SSF48695 89 549 3.74E-95 T 13-10-2018 IPR036280 Multiheme cytochrome superfamily THITH_16205 efbad63039a5208147090012ac92922c 553 Gene3D G3DSA:1.20.140.10 446 553 4.4E-47 T 13-10-2018 THITH_16205 efbad63039a5208147090012ac92922c 553 Gene3D G3DSA:1.10.1130.10 91 445 1.3E-151 T 13-10-2018 THITH_16205 efbad63039a5208147090012ac92922c 553 Pfam PF02335 Cytochrome c552 181 546 5.6E-58 T 13-10-2018 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 THITH_02795 44e2b1444d17a3a75ab6735c5ff9ea8b 244 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 135 162 1.4E-5 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like THITH_02795 44e2b1444d17a3a75ab6735c5ff9ea8b 244 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 47 67 1.4E-5 T 13-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like THITH_02795 44e2b1444d17a3a75ab6735c5ff9ea8b 244 TIGRFAM TIGR03420 DnaA_homol_Hda: DnaA regulatory inactivator Hda 5 235 1.0E-74 T 13-10-2018 IPR017788 DnaA regulatory inactivator Hda GO:0032297 THITH_02795 44e2b1444d17a3a75ab6735c5ff9ea8b 244 Gene3D G3DSA:3.40.50.300 1 168 2.0E-37 T 13-10-2018 THITH_02795 44e2b1444d17a3a75ab6735c5ff9ea8b 244 SUPERFAMILY SSF52540 32 216 2.1E-27 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_02795 44e2b1444d17a3a75ab6735c5ff9ea8b 244 Pfam PF00308 Bacterial dnaA protein 15 214 1.6E-20 T 13-10-2018 IPR013317 Chromosomal replication initiator protein DnaA THITH_02795 44e2b1444d17a3a75ab6735c5ff9ea8b 244 Gene3D G3DSA:1.10.8.60 170 236 6.9E-22 T 13-10-2018 THITH_03365 58c01e0c16419bf74e638e3ddd279897 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 63 76 5.8E-7 T 13-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THITH_03365 58c01e0c16419bf74e638e3ddd279897 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 221 232 5.8E-7 T 13-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THITH_03365 58c01e0c16419bf74e638e3ddd279897 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 189 202 5.8E-7 T 13-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THITH_03365 58c01e0c16419bf74e638e3ddd279897 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 130 148 5.8E-7 T 13-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THITH_03365 58c01e0c16419bf74e638e3ddd279897 420 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 13 378 2.4E-120 T 13-10-2018 IPR030931 Group II intron reverse transcriptase/maturase THITH_03365 58c01e0c16419bf74e638e3ddd279897 420 Pfam PF08388 Group II intron, maturase-specific domain 314 388 7.3E-13 T 13-10-2018 IPR013597 Group II intron, maturase-specific THITH_03365 58c01e0c16419bf74e638e3ddd279897 420 SUPERFAMILY SSF56672 21 377 7.91E-61 T 13-10-2018 THITH_03365 58c01e0c16419bf74e638e3ddd279897 420 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 68 288 1.6E-44 T 13-10-2018 IPR000477 Reverse transcriptase domain THITH_03985 58c01e0c16419bf74e638e3ddd279897 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 63 76 5.8E-7 T 13-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THITH_03985 58c01e0c16419bf74e638e3ddd279897 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 221 232 5.8E-7 T 13-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THITH_03985 58c01e0c16419bf74e638e3ddd279897 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 189 202 5.8E-7 T 13-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THITH_03985 58c01e0c16419bf74e638e3ddd279897 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 130 148 5.8E-7 T 13-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THITH_03985 58c01e0c16419bf74e638e3ddd279897 420 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 13 378 2.4E-120 T 13-10-2018 IPR030931 Group II intron reverse transcriptase/maturase THITH_03985 58c01e0c16419bf74e638e3ddd279897 420 Pfam PF08388 Group II intron, maturase-specific domain 314 388 7.3E-13 T 13-10-2018 IPR013597 Group II intron, maturase-specific THITH_03985 58c01e0c16419bf74e638e3ddd279897 420 SUPERFAMILY SSF56672 21 377 7.91E-61 T 13-10-2018 THITH_03985 58c01e0c16419bf74e638e3ddd279897 420 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 68 288 1.6E-44 T 13-10-2018 IPR000477 Reverse transcriptase domain THITH_13385 58c01e0c16419bf74e638e3ddd279897 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 63 76 5.8E-7 T 13-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THITH_13385 58c01e0c16419bf74e638e3ddd279897 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 221 232 5.8E-7 T 13-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THITH_13385 58c01e0c16419bf74e638e3ddd279897 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 189 202 5.8E-7 T 13-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THITH_13385 58c01e0c16419bf74e638e3ddd279897 420 PRINTS PR00866 RNA-dependent DNA-polymerase (msDNA) signature 130 148 5.8E-7 T 13-10-2018 IPR000123 RNA-directed DNA polymerase (reverse transcriptase), msDNA GO:0003723|GO:0003964|GO:0006278 THITH_13385 58c01e0c16419bf74e638e3ddd279897 420 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 13 378 2.4E-120 T 13-10-2018 IPR030931 Group II intron reverse transcriptase/maturase THITH_13385 58c01e0c16419bf74e638e3ddd279897 420 Pfam PF08388 Group II intron, maturase-specific domain 314 388 7.3E-13 T 13-10-2018 IPR013597 Group II intron, maturase-specific THITH_13385 58c01e0c16419bf74e638e3ddd279897 420 SUPERFAMILY SSF56672 21 377 7.91E-61 T 13-10-2018 THITH_13385 58c01e0c16419bf74e638e3ddd279897 420 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 68 288 1.6E-44 T 13-10-2018 IPR000477 Reverse transcriptase domain THITH_05125 210fa75e057af022fb91eaa8536eae91 369 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 7 198 3.5E-81 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THITH_05125 210fa75e057af022fb91eaa8536eae91 369 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 5 199 1.1E-68 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THITH_05125 210fa75e057af022fb91eaa8536eae91 369 SUPERFAMILY SSF55821 3 203 1.35E-83 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily THITH_05125 210fa75e057af022fb91eaa8536eae91 369 PIRSF PIRSF001259 1 368 1.0E-122 T 13-10-2018 THITH_05125 210fa75e057af022fb91eaa8536eae91 369 Gene3D G3DSA:3.40.50.10990 319 367 2.3E-5 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 THITH_05125 210fa75e057af022fb91eaa8536eae91 369 Gene3D G3DSA:3.40.50.10990 207 316 3.5E-24 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 THITH_05125 210fa75e057af022fb91eaa8536eae91 369 Pfam PF00925 GTP cyclohydrolase II 208 366 9.2E-40 T 13-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 THITH_05125 210fa75e057af022fb91eaa8536eae91 369 Gene3D G3DSA:3.90.870.10 1 206 1.4E-84 T 13-10-2018 THITH_05125 210fa75e057af022fb91eaa8536eae91 369 SUPERFAMILY SSF142695 204 366 4.45E-47 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 THITH_05125 210fa75e057af022fb91eaa8536eae91 369 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 203 37.271 T 13-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 THITH_16870 e92545418d63bd00941097f9c99847a1 380 SMART SM00065 75 223 3.7E-7 T 13-10-2018 IPR003018 GAF domain GO:0005515 THITH_16870 e92545418d63bd00941097f9c99847a1 380 Pfam PF13185 GAF domain 74 214 2.6E-15 T 13-10-2018 IPR003018 GAF domain GO:0005515 THITH_16870 e92545418d63bd00941097f9c99847a1 380 SUPERFAMILY SSF55781 55 221 4.36E-23 T 13-10-2018 THITH_16870 e92545418d63bd00941097f9c99847a1 380 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 225 378 1.4E-45 T 13-10-2018 IPR000160 GGDEF domain THITH_16870 e92545418d63bd00941097f9c99847a1 380 SMART SM00267 215 379 1.5E-60 T 13-10-2018 IPR000160 GGDEF domain THITH_16870 e92545418d63bd00941097f9c99847a1 380 Pfam PF00990 Diguanylate cyclase, GGDEF domain 227 374 1.4E-42 T 13-10-2018 IPR000160 GGDEF domain THITH_16870 e92545418d63bd00941097f9c99847a1 380 Gene3D G3DSA:3.30.450.40 48 222 1.3E-31 T 13-10-2018 IPR029016 GAF-like domain superfamily THITH_16870 e92545418d63bd00941097f9c99847a1 380 Gene3D G3DSA:3.30.70.270 223 379 7.4E-55 T 13-10-2018 THITH_16870 e92545418d63bd00941097f9c99847a1 380 SUPERFAMILY SSF55073 231 378 8.63E-47 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_12375 302e790533a5b89033e63ff98d61e831 156 Pfam PF04073 Aminoacyl-tRNA editing domain 23 142 3.3E-25 T 13-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 THITH_12375 302e790533a5b89033e63ff98d61e831 156 SUPERFAMILY SSF55826 7 146 3.14E-30 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 THITH_12375 302e790533a5b89033e63ff98d61e831 156 Gene3D G3DSA:3.90.960.10 3 147 6.0E-42 T 13-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 THITH_10350 cbbe13d5816b17a26bee2e439ced9a27 384 Pfam PF00146 NADH dehydrogenase 13 374 9.9E-101 T 13-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10350 cbbe13d5816b17a26bee2e439ced9a27 384 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 4 380 21.379 T 13-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10350 cbbe13d5816b17a26bee2e439ced9a27 384 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 246 259 - T 13-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 635 651 1.0E-18 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 491 509 1.0E-18 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 667 692 1.0E-18 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 607 623 1.0E-18 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 Gene3D G3DSA:3.40.1110.10 340 541 3.3E-298 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 635 654 3.8E-39 T 13-10-2018 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 659 671 3.8E-39 T 13-10-2018 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 534 545 3.8E-39 T 13-10-2018 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 556 566 3.8E-39 T 13-10-2018 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 330 344 3.8E-39 T 13-10-2018 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 167 181 3.8E-39 T 13-10-2018 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 SUPERFAMILY SSF81653 119 228 3.79E-31 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 Pfam PF00122 E1-E2 ATPase 117 309 2.4E-53 T 13-10-2018 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 Pfam PF00702 haloacid dehalogenase-like hydrolase 326 649 2.3E-21 T 13-10-2018 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 Gene3D G3DSA:1.20.1110.10 60 890 3.3E-298 T 13-10-2018 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 Pfam PF00689 Cation transporting ATPase, C-terminus 720 892 3.9E-44 T 13-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 Pfam PF00690 Cation transporter/ATPase, N-terminus 10 75 4.1E-18 T 13-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 SUPERFAMILY SSF81660 337 538 4.58E-52 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 332 338 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 606 725 4.1E-32 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 88 352 1.1E-42 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 SUPERFAMILY SSF56784 328 740 2.2E-61 T 13-10-2018 IPR036412 HAD-like superfamily THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 Gene3D G3DSA:2.70.150.10 24 232 3.3E-298 T 13-10-2018 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 Gene3D G3DSA:3.40.50.1000 327 680 3.3E-298 T 13-10-2018 IPR023214 HAD superfamily THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 SMART SM00831 9 82 1.5E-36 T 13-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 THITH_04155 03b2118c94f9e9bb134c1e9bbdbd6433 902 SUPERFAMILY SSF81665 9 895 8.24E-127 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 THITH_13285 744cb3f623872d9c33ed454fac387a0e 429 Pfam PF09242 Flavocytochrome c sulphide dehydrogenase, flavin-binding 361 428 1.5E-26 T 13-10-2018 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 THITH_13285 744cb3f623872d9c33ed454fac387a0e 429 Gene3D G3DSA:3.90.760.10 359 429 1.1E-23 T 13-10-2018 IPR037092 Flavocytochrome c sulphide dehydrogenase, flavin-binding domain superfamily GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 THITH_13285 744cb3f623872d9c33ed454fac387a0e 429 SUPERFAMILY SSF51905 39 357 2.55E-30 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_13285 744cb3f623872d9c33ed454fac387a0e 429 SUPERFAMILY SSF51905 151 286 1.94E-40 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_13285 744cb3f623872d9c33ed454fac387a0e 429 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 39 144 4.2E-11 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THITH_13285 744cb3f623872d9c33ed454fac387a0e 429 Gene3D G3DSA:3.50.50.60 39 348 3.0E-111 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_13285 744cb3f623872d9c33ed454fac387a0e 429 Gene3D G3DSA:3.50.50.60 153 286 3.0E-111 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_13285 744cb3f623872d9c33ed454fac387a0e 429 SUPERFAMILY SSF55424 360 429 4.39E-18 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THITH_15715 f39d33d5b911b8ae5b6d350ec67d53f4 144 SUPERFAMILY SSF54523 20 133 5.41E-19 T 13-10-2018 THITH_15715 f39d33d5b911b8ae5b6d350ec67d53f4 144 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 18 38 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_15715 f39d33d5b911b8ae5b6d350ec67d53f4 144 Gene3D G3DSA:3.30.700.10 20 139 2.7E-16 T 13-10-2018 THITH_15715 f39d33d5b911b8ae5b6d350ec67d53f4 144 Pfam PF07963 Prokaryotic N-terminal methylation motif 17 39 4.2E-8 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_15715 f39d33d5b911b8ae5b6d350ec67d53f4 144 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 41 125 2.9E-18 T 13-10-2018 IPR031982 Type IV minor pilin ComP THITH_15715 f39d33d5b911b8ae5b6d350ec67d53f4 144 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 18 39 1.3E-7 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_14605 ffe40cf64dc1b4e0c6f38af171b85e41 222 Pfam PF05494 MlaC protein 37 199 5.1E-46 T 13-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC THITH_14605 ffe40cf64dc1b4e0c6f38af171b85e41 222 Gene3D G3DSA:3.10.450.710 27 204 2.5E-45 T 13-10-2018 THITH_14605 ffe40cf64dc1b4e0c6f38af171b85e41 222 PIRSF PIRSF004649 1 210 3.6E-51 T 13-10-2018 IPR008869 Toluene tolerance Ttg2/phospholipid-binding protein MlaC THITH_08460 902bb298b50edb167387bcf1cbc69420 1737 SMART SM01359 870 1014 9.4E-22 T 13-10-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 THITH_08460 902bb298b50edb167387bcf1cbc69420 1737 Pfam PF00207 Alpha-2-macroglobulin family 1076 1154 3.1E-8 T 13-10-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 THITH_08460 902bb298b50edb167387bcf1cbc69420 1737 SMART SM01360 1075 1163 5.2E-26 T 13-10-2018 IPR001599 Alpha-2-macroglobulin GO:0004866 THITH_08460 902bb298b50edb167387bcf1cbc69420 1737 SUPERFAMILY SSF48239 1274 1517 1.92E-28 T 13-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid THITH_08460 902bb298b50edb167387bcf1cbc69420 1737 Pfam PF11974 Alpha-2-macroglobulin MG1 domain 400 500 7.6E-24 T 13-10-2018 THITH_08460 902bb298b50edb167387bcf1cbc69420 1737 Pfam PF07703 Alpha-2-macroglobulin family N-terminal region 870 1014 1.4E-7 T 13-10-2018 IPR011625 Alpha-2-macroglobulin, N-terminal 2 THITH_08460 902bb298b50edb167387bcf1cbc69420 1737 Gene3D G3DSA:1.50.10.20 1273 1520 9.4E-16 T 13-10-2018 THITH_08460 902bb298b50edb167387bcf1cbc69420 1737 Pfam PF01835 MG2 domain 508 602 2.8E-19 T 13-10-2018 IPR002890 Alpha-2-macroglobulin, N-terminal GO:0004866 THITH_08460 902bb298b50edb167387bcf1cbc69420 1737 PIRSF PIRSF038980 36 1736 0.0 T 13-10-2018 IPR026284 Alpha-2-macroglobulin domain protein, bacteria THITH_13450 ae9d5c11870f9a9d646cd007cfe8864c 456 SUPERFAMILY SSF52540 199 367 7.51E-41 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13450 ae9d5c11870f9a9d646cd007cfe8864c 456 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 222 240 8.5E-10 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_13450 ae9d5c11870f9a9d646cd007cfe8864c 456 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 201 221 8.5E-10 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_13450 ae9d5c11870f9a9d646cd007cfe8864c 456 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 268 286 8.5E-10 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_13450 ae9d5c11870f9a9d646cd007cfe8864c 456 Pfam PF01926 50S ribosome-binding GTPase 201 319 1.3E-19 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_13450 ae9d5c11870f9a9d646cd007cfe8864c 456 Gene3D G3DSA:3.40.50.11060 18 139 1.8E-37 T 13-10-2018 THITH_13450 ae9d5c11870f9a9d646cd007cfe8864c 456 Pfam PF13167 GTP-binding GTPase N-terminal 26 113 4.4E-30 T 13-10-2018 IPR025121 GTPase HflX, N-terminal THITH_13450 ae9d5c11870f9a9d646cd007cfe8864c 456 Pfam PF16360 GTP-binding GTPase Middle Region 115 193 1.5E-28 T 13-10-2018 IPR032305 GTP-binding protein, middle domain THITH_13450 ae9d5c11870f9a9d646cd007cfe8864c 456 Hamap MF_00900 GTPase HflX [hflX]. 28 391 47.708 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 THITH_13450 ae9d5c11870f9a9d646cd007cfe8864c 456 PIRSF PIRSF006809 3 421 7.1E-145 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 THITH_13450 ae9d5c11870f9a9d646cd007cfe8864c 456 Gene3D G3DSA:3.40.50.300 198 367 1.1E-39 T 13-10-2018 THITH_13450 ae9d5c11870f9a9d646cd007cfe8864c 456 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 10 361 3.8E-149 T 13-10-2018 IPR016496 GTPase HflX GO:0005525 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 SUPERFAMILY SSF52021 4 147 1.83E-57 T 13-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 3 376 47.787 T 13-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 Gene3D G3DSA:3.40.50.880 151 375 1.2E-69 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 PRINTS PR00097 Anthranilate synthase component II signature 262 273 1.4E-6 T 13-10-2018 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 PRINTS PR00097 Anthranilate synthase component II signature 234 243 1.4E-6 T 13-10-2018 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 PRINTS PR00097 Anthranilate synthase component II signature 347 360 1.4E-6 T 13-10-2018 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 231 245 4.9E-40 T 13-10-2018 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 279 296 4.9E-40 T 13-10-2018 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 304 315 4.9E-40 T 13-10-2018 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 192 206 4.9E-40 T 13-10-2018 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 262 278 4.9E-40 T 13-10-2018 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 PRINTS PR00096 Glutamine amidotransferase superfamily signature 347 360 1.3E-11 T 13-10-2018 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 PRINTS PR00096 Glutamine amidotransferase superfamily signature 262 273 1.3E-11 T 13-10-2018 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 PRINTS PR00096 Glutamine amidotransferase superfamily signature 234 243 1.3E-11 T 13-10-2018 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 SMART SM01097 3 133 8.1E-92 T 13-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 5 131 9.2E-53 T 13-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 5 373 3.1E-144 T 13-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 Gene3D G3DSA:3.50.30.20 3 150 2.9E-59 T 13-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 SUPERFAMILY SSF52317 186 374 1.14E-57 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_13045 8c9efc510a893e4b63d71b40fab89f08 377 Pfam PF00117 Glutamine amidotransferase class-I 195 370 5.7E-44 T 13-10-2018 IPR017926 Glutamine amidotransferase THITH_16965 5f463e3352bf02e20d5b3a931d245ef0 208 SUPERFAMILY SSF53335 17 205 3.35E-33 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_16965 5f463e3352bf02e20d5b3a931d245ef0 208 Gene3D G3DSA:3.40.50.150 3 208 5.7E-56 T 13-10-2018 THITH_16965 5f463e3352bf02e20d5b3a931d245ef0 208 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 27 172 9.8E-42 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 THITH_16965 5f463e3352bf02e20d5b3a931d245ef0 208 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 15 202 24.036 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 THITH_16965 5f463e3352bf02e20d5b3a931d245ef0 208 Pfam PF02527 rRNA small subunit methyltransferase G 27 174 3.2E-43 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 THITH_16965 5f463e3352bf02e20d5b3a931d245ef0 208 PIRSF PIRSF003078 6 208 1.4E-44 T 13-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 Pfam PF05190 MutS family domain IV 431 521 4.0E-28 T 13-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 692 708 - T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 Gene3D G3DSA:3.30.420.110 131 264 5.4E-28 T 13-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 Pfam PF00488 MutS domain V 614 801 5.9E-84 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 Gene3D G3DSA:1.10.1420.10 269 562 5.3E-96 T 13-10-2018 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 PIRSF PIRSF037677 226 815 3.0E-126 T 13-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 PIRSF PIRSF037677 2 192 5.8E-27 T 13-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 Gene3D G3DSA:1.10.1420.10 390 506 5.3E-96 T 13-10-2018 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 Pfam PF05188 MutS domain II 131 255 1.2E-20 T 13-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 SMART SM00533 286 594 3.7E-89 T 13-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 SUPERFAMILY SSF55271 5 116 5.62E-41 T 13-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 Gene3D G3DSA:3.40.50.300 572 815 3.0E-101 T 13-10-2018 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 Gene3D G3DSA:3.40.1170.10 3 124 1.8E-48 T 13-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 SUPERFAMILY SSF48334 270 568 5.89E-84 T 13-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily THITH_09400 7c286cefe135c2447b1443fefaff890e 860 SMART SM00534 611 798 5.7E-113 T 13-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 SUPERFAMILY SSF52540 570 802 3.6E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_09400 7c286cefe135c2447b1443fefaff890e 860 SUPERFAMILY SSF53150 121 283 1.96E-33 T 13-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 10 856 0.0 T 13-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 Pfam PF05192 MutS domain III 272 562 3.9E-38 T 13-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 Pfam PF01624 MutS domain I 11 122 3.3E-40 T 13-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 THITH_09400 7c286cefe135c2447b1443fefaff890e 860 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 10 851 24.368 T 13-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 THITH_12970 8d1647a5abd5f5ed2e53586ddac8ff33 167 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 19 165 3.1E-52 T 13-10-2018 THITH_12970 8d1647a5abd5f5ed2e53586ddac8ff33 167 SUPERFAMILY SSF52833 12 165 1.07E-51 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_12970 8d1647a5abd5f5ed2e53586ddac8ff33 167 Gene3D G3DSA:1.10.10.1590 11 81 6.2E-24 T 13-10-2018 THITH_12970 8d1647a5abd5f5ed2e53586ddac8ff33 167 PIRSF PIRSF000216 2 167 6.4E-61 T 13-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12970 8d1647a5abd5f5ed2e53586ddac8ff33 167 Gene3D G3DSA:3.40.30.10 82 164 6.9E-28 T 13-10-2018 THITH_12970 8d1647a5abd5f5ed2e53586ddac8ff33 167 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 18 166 1.8E-59 T 13-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04895 0b92f1d0f26c55039cffeab76eac9952 511 Gene3D G3DSA:3.40.50.300 64 310 1.1E-35 T 13-10-2018 THITH_04895 0b92f1d0f26c55039cffeab76eac9952 511 SUPERFAMILY SSF52540 61 283 1.22E-18 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_04895 0b92f1d0f26c55039cffeab76eac9952 511 Pfam PF00350 Dynamin family 64 230 2.5E-15 T 13-10-2018 IPR022812 Dynamin superfamily THITH_01350 15b33b1278cd0f67fc4f7f9c26e1cd2d 217 Gene3D G3DSA:3.40.50.300 1 216 5.8E-79 T 13-10-2018 THITH_01350 15b33b1278cd0f67fc4f7f9c26e1cd2d 217 SUPERFAMILY SSF52540 1 215 9.35E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01350 15b33b1278cd0f67fc4f7f9c26e1cd2d 217 Hamap MF_00235 Adenylate kinase [adk]. 1 217 55.067 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THITH_01350 15b33b1278cd0f67fc4f7f9c26e1cd2d 217 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 13-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THITH_01350 15b33b1278cd0f67fc4f7f9c26e1cd2d 217 PRINTS PR00094 Adenylate kinase signature 81 97 6.1E-37 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THITH_01350 15b33b1278cd0f67fc4f7f9c26e1cd2d 217 PRINTS PR00094 Adenylate kinase signature 4 17 6.1E-37 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THITH_01350 15b33b1278cd0f67fc4f7f9c26e1cd2d 217 PRINTS PR00094 Adenylate kinase signature 32 46 6.1E-37 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THITH_01350 15b33b1278cd0f67fc4f7f9c26e1cd2d 217 PRINTS PR00094 Adenylate kinase signature 156 171 6.1E-37 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THITH_01350 15b33b1278cd0f67fc4f7f9c26e1cd2d 217 PRINTS PR00094 Adenylate kinase signature 173 187 6.1E-37 T 13-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 THITH_01350 15b33b1278cd0f67fc4f7f9c26e1cd2d 217 Pfam PF05191 Adenylate kinase, active site lid 123 158 8.3E-18 T 13-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 THITH_01350 15b33b1278cd0f67fc4f7f9c26e1cd2d 217 TIGRFAM TIGR01351 adk: adenylate kinase 2 190 2.0E-75 T 13-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 THITH_01350 15b33b1278cd0f67fc4f7f9c26e1cd2d 217 Pfam PF00406 Adenylate kinase 5 185 3.1E-59 T 13-10-2018 THITH_15845 a984d9d041f12a14623c9c275c4c6b31 211 Pfam PF00027 Cyclic nucleotide-binding domain 24 111 2.2E-25 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain THITH_15845 a984d9d041f12a14623c9c275c4c6b31 211 SUPERFAMILY SSF46785 140 208 2.92E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_15845 a984d9d041f12a14623c9c275c4c6b31 211 Gene3D G3DSA:1.10.10.10 140 208 8.1E-34 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_15845 a984d9d041f12a14623c9c275c4c6b31 211 ProSitePatterns PS00042 Crp-type HTH domain signature. 169 192 - T 13-10-2018 IPR018335 Transcription regulator HTH, Crp-type, conserved site GO:0003700|GO:0005622|GO:0006355 THITH_15845 a984d9d041f12a14623c9c275c4c6b31 211 Pfam PF00325 Bacterial regulatory proteins, crp family 167 198 3.0E-13 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THITH_15845 a984d9d041f12a14623c9c275c4c6b31 211 Gene3D G3DSA:2.60.120.10 13 139 1.2E-39 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_15845 a984d9d041f12a14623c9c275c4c6b31 211 SUPERFAMILY SSF51206 12 138 7.99E-36 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like THITH_15845 a984d9d041f12a14623c9c275c4c6b31 211 SMART SM00419 161 209 6.4E-14 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THITH_15845 a984d9d041f12a14623c9c275c4c6b31 211 SMART SM00100 6 123 2.5E-24 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain THITH_15845 a984d9d041f12a14623c9c275c4c6b31 211 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 167 183 6.5E-7 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THITH_15845 a984d9d041f12a14623c9c275c4c6b31 211 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 183 198 6.5E-7 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THITH_02540 7904f9dbcb1b0491c2afd8b5abf36095 343 Gene3D G3DSA:3.40.50.720 4 329 9.4E-129 T 13-10-2018 THITH_02540 7904f9dbcb1b0491c2afd8b5abf36095 343 SUPERFAMILY SSF55347 149 311 8.37E-51 T 13-10-2018 THITH_02540 7904f9dbcb1b0491c2afd8b5abf36095 343 Gene3D G3DSA:3.30.360.10 147 311 9.4E-129 T 13-10-2018 THITH_02540 7904f9dbcb1b0491c2afd8b5abf36095 343 SUPERFAMILY SSF51735 2 174 5.78E-56 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_02540 7904f9dbcb1b0491c2afd8b5abf36095 343 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 158 314 2.2E-19 T 13-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THITH_02540 7904f9dbcb1b0491c2afd8b5abf36095 343 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 144 160 - T 13-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THITH_02540 7904f9dbcb1b0491c2afd8b5abf36095 343 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 2 337 43.679 T 13-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THITH_02540 7904f9dbcb1b0491c2afd8b5abf36095 343 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 343 1.9E-128 T 13-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THITH_02540 7904f9dbcb1b0491c2afd8b5abf36095 343 SMART SM00859 3 141 3.0E-62 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THITH_02540 7904f9dbcb1b0491c2afd8b5abf36095 343 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 140 3.9E-37 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THITH_17030 ee3010e397d5497dec608870a4d19441 615 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 615 2.0E-245 T 13-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 THITH_17030 ee3010e397d5497dec608870a4d19441 615 Pfam PF01380 SIS domain 466 597 9.4E-27 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 THITH_17030 ee3010e397d5497dec608870a4d19441 615 Pfam PF01380 SIS domain 291 419 1.8E-28 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 THITH_17030 ee3010e397d5497dec608870a4d19441 615 Pfam PF13522 Glutamine amidotransferase domain 62 180 9.6E-25 T 13-10-2018 THITH_17030 ee3010e397d5497dec608870a4d19441 615 SUPERFAMILY SSF56235 2 234 4.89E-69 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_17030 ee3010e397d5497dec608870a4d19441 615 Gene3D G3DSA:3.60.20.10 2 242 4.2E-75 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_17030 ee3010e397d5497dec608870a4d19441 615 Gene3D G3DSA:3.40.50.10490 250 614 1.9E-140 T 13-10-2018 THITH_17030 ee3010e397d5497dec608870a4d19441 615 Gene3D G3DSA:3.40.50.10490 451 600 1.9E-140 T 13-10-2018 THITH_17030 ee3010e397d5497dec608870a4d19441 615 SUPERFAMILY SSF53697 246 615 5.94E-105 T 13-10-2018 THITH_17030 ee3010e397d5497dec608870a4d19441 615 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 615 39.691 T 13-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 THITH_04275 2ee472b62460a21ed3a3541c9c8ca92d 332 Gene3D G3DSA:1.10.540.10 1 67 3.5E-10 T 13-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 THITH_04275 2ee472b62460a21ed3a3541c9c8ca92d 332 Gene3D G3DSA:1.20.140.10 183 328 1.4E-26 T 13-10-2018 THITH_04275 2ee472b62460a21ed3a3541c9c8ca92d 332 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 1 65 5.0E-7 T 13-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 THITH_04275 2ee472b62460a21ed3a3541c9c8ca92d 332 SUPERFAMILY SSF56645 1 176 2.88E-46 T 13-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 THITH_04275 2ee472b62460a21ed3a3541c9c8ca92d 332 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 178 326 3.6E-27 T 13-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 THITH_04275 2ee472b62460a21ed3a3541c9c8ca92d 332 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 70 166 3.8E-24 T 13-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 THITH_04275 2ee472b62460a21ed3a3541c9c8ca92d 332 Gene3D G3DSA:2.40.110.10 69 182 1.9E-32 T 13-10-2018 THITH_04275 2ee472b62460a21ed3a3541c9c8ca92d 332 SUPERFAMILY SSF47203 178 327 2.26E-27 T 13-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 THITH_12490 16e631a9d0f5f0bf30e1cfe58447bd64 627 SUPERFAMILY SSF56784 29 227 1.24E-10 T 13-10-2018 IPR036412 HAD-like superfamily THITH_12490 16e631a9d0f5f0bf30e1cfe58447bd64 627 Gene3D G3DSA:3.40.50.1000 29 234 2.9E-6 T 13-10-2018 IPR023214 HAD superfamily THITH_10065 e255e5813912c12e5d61b9aa49a8a96e 421 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 108 116 - T 13-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 THITH_10065 e255e5813912c12e5d61b9aa49a8a96e 421 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 16 388 1.1E-158 T 13-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 THITH_10065 e255e5813912c12e5d61b9aa49a8a96e 421 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 22 41 - T 13-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 THITH_10065 e255e5813912c12e5d61b9aa49a8a96e 421 SUPERFAMILY SSF53448 14 369 8.68E-83 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_10065 e255e5813912c12e5d61b9aa49a8a96e 421 SUPERFAMILY SSF51161 302 406 3.09E-19 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily THITH_10065 e255e5813912c12e5d61b9aa49a8a96e 421 Pfam PF00483 Nucleotidyl transferase 18 280 3.1E-67 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 THITH_10065 e255e5813912c12e5d61b9aa49a8a96e 421 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 13 414 52.292 T 13-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 THITH_10065 e255e5813912c12e5d61b9aa49a8a96e 421 Gene3D G3DSA:2.160.10.10 292 420 3.7E-40 T 13-10-2018 THITH_10065 e255e5813912c12e5d61b9aa49a8a96e 421 Gene3D G3DSA:3.90.550.10 7 291 1.5E-91 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_14790 4f7b4a35553819640e2a321c4cff355e 289 Pfam PF08544 GHMP kinases C terminal 209 257 4.6E-6 T 13-10-2018 IPR013750 GHMP kinase, C-terminal domain THITH_14790 4f7b4a35553819640e2a321c4cff355e 289 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 7 273 30.923 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 THITH_14790 4f7b4a35553819640e2a321c4cff355e 289 SUPERFAMILY SSF55060 162 277 9.21E-26 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily THITH_14790 4f7b4a35553819640e2a321c4cff355e 289 Gene3D G3DSA:3.30.70.890 162 280 4.1E-25 T 13-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily THITH_14790 4f7b4a35553819640e2a321c4cff355e 289 PIRSF PIRSF010376 6 280 1.4E-75 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 THITH_14790 4f7b4a35553819640e2a321c4cff355e 289 Pfam PF00288 GHMP kinases N terminal domain 88 145 1.6E-10 T 13-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 THITH_14790 4f7b4a35553819640e2a321c4cff355e 289 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 7 276 1.0E-69 T 13-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 THITH_14790 4f7b4a35553819640e2a321c4cff355e 289 SUPERFAMILY SSF54211 8 159 4.55E-42 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_14790 4f7b4a35553819640e2a321c4cff355e 289 Gene3D G3DSA:3.30.230.10 2 160 2.4E-54 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THITH_02615 702e0051049046f23d1ce5d67443d353 472 Gene3D G3DSA:3.40.50.300 258 470 2.5E-63 T 13-10-2018 THITH_02615 702e0051049046f23d1ce5d67443d353 472 SUPERFAMILY SSF88723 11 162 4.32E-13 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_02615 702e0051049046f23d1ce5d67443d353 472 Pfam PF13638 PIN domain 12 162 5.4E-40 T 13-10-2018 IPR002716 PIN domain THITH_02615 702e0051049046f23d1ce5d67443d353 472 Gene3D G3DSA:3.40.50.1010 6 165 1.1E-22 T 13-10-2018 THITH_02615 702e0051049046f23d1ce5d67443d353 472 SMART SM00670 10 150 5.4E-11 T 13-10-2018 IPR002716 PIN domain THITH_02615 702e0051049046f23d1ce5d67443d353 472 Pfam PF02562 PhoH-like protein 260 460 7.5E-54 T 13-10-2018 IPR003714 PhoH-like protein GO:0005524 THITH_02615 702e0051049046f23d1ce5d67443d353 472 SUPERFAMILY SSF52540 259 453 1.07E-28 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 SUPERFAMILY SSF51905 132 509 1.61E-53 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 Gene3D G3DSA:3.30.390.30 474 594 6.0E-41 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 133 589 3.4E-146 T 13-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 475 580 1.1E-31 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 167 177 - T 13-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 SUPERFAMILY SSF55424 471 592 5.5E-37 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 13-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 166 181 2.2E-71 T 13-10-2018 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 435 442 2.2E-71 T 13-10-2018 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 392 406 2.2E-71 T 13-10-2018 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 535 550 2.2E-71 T 13-10-2018 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 557 577 2.2E-71 T 13-10-2018 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 471 492 2.2E-71 T 13-10-2018 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 133 155 2.2E-71 T 13-10-2018 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 275 2.2E-71 T 13-10-2018 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 302 327 2.2E-71 T 13-10-2018 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 Pfam PF00364 Biotin-requiring enzyme 6 76 4.8E-21 T 13-10-2018 IPR000089 Biotin/lipoyl attachment THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 133 455 9.6E-59 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 Gene3D G3DSA:3.50.50.60 134 459 7.0E-112 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 Gene3D G3DSA:2.40.50.100 4 81 1.8E-21 T 13-10-2018 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 134 153 5.7E-37 T 13-10-2018 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 281 5.7E-37 T 13-10-2018 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 391 407 5.7E-37 T 13-10-2018 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 302 320 5.7E-37 T 13-10-2018 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 420 442 5.7E-37 T 13-10-2018 THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 SUPERFAMILY SSF51230 3 94 1.81E-22 T 13-10-2018 IPR011053 Single hybrid motif THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 Gene3D G3DSA:3.50.50.60 275 398 7.0E-112 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_14740 71f1a41da1e0215d44599f7ff3bbfcc1 599 PIRSF PIRSF000350 95 593 5.0E-81 T 13-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 THITH_06655 3941d8cd797df0959ca3ae2836074989 292 Pfam PF09084 NMT1/THI5 like 11 166 2.2E-17 T 13-10-2018 IPR015168 SsuA/THI5-like THITH_06655 3941d8cd797df0959ca3ae2836074989 292 Gene3D G3DSA:3.40.190.10 1 89 1.5E-8 T 13-10-2018 THITH_06655 3941d8cd797df0959ca3ae2836074989 292 Gene3D G3DSA:3.40.190.10 96 282 1.9E-18 T 13-10-2018 THITH_06655 3941d8cd797df0959ca3ae2836074989 292 SUPERFAMILY SSF53850 2 214 3.35E-30 T 13-10-2018 THITH_13515 5cce01c8a828f79440750151818fff86 501 Pfam PF01957 NfeD-like C-terminal, partner-binding 354 489 1.0E-32 T 13-10-2018 IPR002810 NfeD-like, C-terminal domain THITH_13515 5cce01c8a828f79440750151818fff86 501 SUPERFAMILY SSF141322 424 490 2.09E-13 T 13-10-2018 THITH_13515 5cce01c8a828f79440750151818fff86 501 SUPERFAMILY SSF52096 40 254 3.91E-24 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THITH_13515 5cce01c8a828f79440750151818fff86 501 Gene3D G3DSA:2.40.50.140 427 497 1.4E-18 T 13-10-2018 THITH_17315 b26f201a2751d31e871e18f73d1bbdd1 649 Gene3D G3DSA:3.30.70.330 492 564 3.6E-10 T 13-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily THITH_17315 b26f201a2751d31e871e18f73d1bbdd1 649 Gene3D G3DSA:3.40.50.300 1 211 6.0E-74 T 13-10-2018 THITH_17315 b26f201a2751d31e871e18f73d1bbdd1 649 SUPERFAMILY SSF52540 73 359 9.18E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_17315 b26f201a2751d31e871e18f73d1bbdd1 649 Pfam PF00270 DEAD/DEAH box helicase 29 193 6.1E-48 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THITH_17315 b26f201a2751d31e871e18f73d1bbdd1 649 Pfam PF03880 DbpA RNA binding domain 493 561 1.8E-16 T 13-10-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain THITH_17315 b26f201a2751d31e871e18f73d1bbdd1 649 Gene3D G3DSA:3.40.50.300 216 410 2.8E-47 T 13-10-2018 THITH_17315 b26f201a2751d31e871e18f73d1bbdd1 649 SMART SM00487 24 222 8.0E-59 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_17315 b26f201a2751d31e871e18f73d1bbdd1 649 Pfam PF00271 Helicase conserved C-terminal domain 231 340 1.0E-27 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_17315 b26f201a2751d31e871e18f73d1bbdd1 649 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 153 161 - T 13-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site THITH_17315 b26f201a2751d31e871e18f73d1bbdd1 649 SMART SM00490 259 340 6.3E-31 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 SUPERFAMILY SSF52540 360 469 7.96E-19 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 151 1086 0.0 T 13-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 Gene3D G3DSA:3.40.50.11140 362 457 3.2E-9 T 13-10-2018 THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 Pfam PF02559 CarD-like/TRCF domain 484 577 4.5E-23 T 13-10-2018 IPR003711 CarD-like/TRCF domain THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 SUPERFAMILY SSF52540 17 344 5.71E-93 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 Gene3D G3DSA:3.30.2060.10 134 219 6.2E-107 T 13-10-2018 THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 Pfam PF00270 DEAD/DEAH box helicase 609 768 1.7E-18 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 SMART SM00487 604 794 1.2E-29 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 SUPERFAMILY SSF141259 475 552 4.58E-22 T 13-10-2018 IPR036101 CarD-like/TRCF domain superfamily THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 SUPERFAMILY SSF52540 527 787 7.65E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 Gene3D G3DSA:3.40.50.11180 32 336 6.2E-107 T 13-10-2018 THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 Gene3D G3DSA:3.40.50.300 482 993 2.3E-229 T 13-10-2018 THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 29 1113 27.444 T 13-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 SMART SM01058 483 580 1.1E-45 T 13-10-2018 IPR003711 CarD-like/TRCF domain THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 Gene3D G3DSA:3.40.50.300 546 785 2.3E-229 T 13-10-2018 THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 Pfam PF00271 Helicase conserved C-terminal domain 810 913 3.3E-15 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 Gene3D G3DSA:2.30.30.840 487 545 2.3E-229 T 13-10-2018 THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 SMART SM00490 830 914 8.1E-17 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 SUPERFAMILY SSF52540 786 994 6.78E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 Pfam PF03461 TRCF domain 1014 1105 7.8E-23 T 13-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 Gene3D G3DSA:3.90.1150.50 1008 1155 7.2E-39 T 13-10-2018 IPR037235 TRCF-like, C-terminal domain THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 SUPERFAMILY SSF143517 1007 1150 3.27E-37 T 13-10-2018 IPR037235 TRCF-like, C-terminal domain THITH_07880 0e54595d33f3187d7999216c71d3f636 1156 SMART SM00982 1012 1112 1.9E-42 T 13-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 THITH_10835 886a2dc26cb134a34b970f8a208b9369 148 Gene3D G3DSA:2.40.70.10 25 147 1.4E-29 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily THITH_10835 886a2dc26cb134a34b970f8a208b9369 148 TIGRFAM TIGR02281 clan_AA_DTGA: clan AA aspartic protease, TIGR02281 family 32 146 1.8E-24 T 13-10-2018 IPR011969 Clan AA aspartic peptidase, C-terminal THITH_10835 886a2dc26cb134a34b970f8a208b9369 148 Pfam PF13975 gag-polyprotein putative aspartyl protease 45 133 1.1E-21 T 13-10-2018 THITH_10835 886a2dc26cb134a34b970f8a208b9369 148 SUPERFAMILY SSF50630 37 136 2.4E-15 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily THITH_16990 5c798d715b44babd4ee684ddef6478f2 79 Pfam PF00137 ATP synthase subunit C 11 71 5.2E-8 T 13-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 THITH_16990 5c798d715b44babd4ee684ddef6478f2 79 SUPERFAMILY SSF81333 2 76 1.57E-16 T 13-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily THITH_16990 5c798d715b44babd4ee684ddef6478f2 79 Gene3D G3DSA:1.20.20.10 1 78 7.3E-28 T 13-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_16990 5c798d715b44babd4ee684ddef6478f2 79 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 19 76 1.6E-29 T 13-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 THITH_16990 5c798d715b44babd4ee684ddef6478f2 79 Hamap MF_01396 ATP synthase subunit c [atpH]. 9 74 13.566 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_16990 5c798d715b44babd4ee684ddef6478f2 79 PRINTS PR00124 ATP synthase C subunit signature 32 47 2.0E-10 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_16990 5c798d715b44babd4ee684ddef6478f2 79 PRINTS PR00124 ATP synthase C subunit signature 49 74 2.0E-10 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_16990 5c798d715b44babd4ee684ddef6478f2 79 PRINTS PR00124 ATP synthase C subunit signature 11 30 2.0E-10 T 13-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_16990 5c798d715b44babd4ee684ddef6478f2 79 ProSitePatterns PS00605 ATP synthase c subunit signature. 39 60 - T 13-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_07775 7cf701f988fbbb6cedc67e6bed9e5819 188 Pfam PF04542 Sigma-70 region 2 21 88 9.7E-14 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 THITH_07775 7cf701f988fbbb6cedc67e6bed9e5819 188 Gene3D G3DSA:1.10.10.10 97 186 2.2E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_07775 7cf701f988fbbb6cedc67e6bed9e5819 188 Gene3D G3DSA:1.10.1740.10 2 85 2.6E-28 T 13-10-2018 THITH_07775 7cf701f988fbbb6cedc67e6bed9e5819 188 SUPERFAMILY SSF88659 101 187 1.55E-13 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like THITH_07775 7cf701f988fbbb6cedc67e6bed9e5819 188 SUPERFAMILY SSF88946 2 101 4.32E-21 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 THITH_07775 7cf701f988fbbb6cedc67e6bed9e5819 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 184 3.3E-22 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 THITH_07775 7cf701f988fbbb6cedc67e6bed9e5819 188 Pfam PF04545 Sigma-70, region 4 134 183 5.0E-8 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 THITH_12230 5bb38cf16b8d8be05a898ff6afd8894a 616 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 3.7E-5 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 THITH_12230 5bb38cf16b8d8be05a898ff6afd8894a 616 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 3.7E-5 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 THITH_12230 5bb38cf16b8d8be05a898ff6afd8894a 616 Pfam PF13177 DNA polymerase III, delta subunit 20 178 2.5E-44 T 13-10-2018 THITH_12230 5bb38cf16b8d8be05a898ff6afd8894a 616 SUPERFAMILY SSF48019 243 368 5.27E-26 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 THITH_12230 5bb38cf16b8d8be05a898ff6afd8894a 616 Gene3D G3DSA:3.40.50.300 13 177 2.5E-101 T 13-10-2018 THITH_12230 5bb38cf16b8d8be05a898ff6afd8894a 616 Pfam PF12170 DNA polymerase III tau subunit V interacting with alpha 496 596 2.1E-10 T 13-10-2018 IPR021029 DNA polymerase III, tau subunit, domain V GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_12230 5bb38cf16b8d8be05a898ff6afd8894a 616 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 361 5.2E-125 T 13-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 THITH_12230 5bb38cf16b8d8be05a898ff6afd8894a 616 SUPERFAMILY SSF52540 30 222 3.05E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_12230 5bb38cf16b8d8be05a898ff6afd8894a 616 SMART SM00382 37 194 1.3E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_12230 5bb38cf16b8d8be05a898ff6afd8894a 616 Gene3D G3DSA:1.20.272.10 242 367 2.6E-34 T 13-10-2018 THITH_12230 5bb38cf16b8d8be05a898ff6afd8894a 616 Gene3D G3DSA:3.30.300.150 478 586 9.1E-7 T 13-10-2018 IPR038249 DNA polymerase III, tau subunit, C-terminal domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_12230 5bb38cf16b8d8be05a898ff6afd8894a 616 Gene3D G3DSA:1.10.8.60 8 237 2.5E-101 T 13-10-2018 THITH_12230 5bb38cf16b8d8be05a898ff6afd8894a 616 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 235 369 6.8E-22 T 13-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 THITH_01390 59abe84c5219b3781d699e97fec93212 177 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 153 2.0E-17 T 13-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 THITH_01390 59abe84c5219b3781d699e97fec93212 177 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 160 1.9E-33 T 13-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 THITH_01390 59abe84c5219b3781d699e97fec93212 177 Gene3D G3DSA:3.60.21.10 1 166 1.4E-34 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like THITH_01390 59abe84c5219b3781d699e97fec93212 177 SUPERFAMILY SSF56300 1 164 9.68E-29 T 13-10-2018 THITH_09155 8a5cd65fe3f2c1279c320e824994f8c6 340 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 1 335 49.814 T 13-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 THITH_09155 8a5cd65fe3f2c1279c320e824994f8c6 340 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 291 311 - T 13-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 THITH_09155 8a5cd65fe3f2c1279c320e824994f8c6 340 SUPERFAMILY SSF51395 1 335 1.36E-98 T 13-10-2018 THITH_09155 8a5cd65fe3f2c1279c320e824994f8c6 340 PIRSF PIRSF000164 10 339 3.8E-94 T 13-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 THITH_09155 8a5cd65fe3f2c1279c320e824994f8c6 340 Pfam PF01180 Dihydroorotate dehydrogenase 44 335 3.5E-87 T 13-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 THITH_09155 8a5cd65fe3f2c1279c320e824994f8c6 340 Gene3D G3DSA:3.20.20.70 1 334 7.1E-128 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_09155 8a5cd65fe3f2c1279c320e824994f8c6 340 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 77 96 - T 13-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 THITH_09155 8a5cd65fe3f2c1279c320e824994f8c6 340 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 2 336 3.7E-123 T 13-10-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 THITH_06885 346e530ae7f7db45c9cfcdafb91934ba 176 SUPERFAMILY SSF52833 40 171 1.54E-33 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_06885 346e530ae7f7db45c9cfcdafb91934ba 176 Gene3D G3DSA:3.40.30.10 23 176 3.2E-38 T 13-10-2018 THITH_06885 346e530ae7f7db45c9cfcdafb91934ba 176 Pfam PF08534 Redoxin 36 155 1.4E-13 T 13-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 THITH_06885 346e530ae7f7db45c9cfcdafb91934ba 176 ProSitePatterns PS00194 Thioredoxin family active site. 65 83 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 THITH_06885 346e530ae7f7db45c9cfcdafb91934ba 176 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 7 170 2.5E-53 T 13-10-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 THITH_17320 c4a4582fca7181e32fa08d6e0bcb455d 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 149 172 1.1E-72 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_17320 c4a4582fca7181e32fa08d6e0bcb455d 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 311 336 1.1E-72 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_17320 c4a4582fca7181e32fa08d6e0bcb455d 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 207 234 1.1E-72 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_17320 c4a4582fca7181e32fa08d6e0bcb455d 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 181 204 1.1E-72 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_17320 c4a4582fca7181e32fa08d6e0bcb455d 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 67 93 1.1E-72 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_17320 c4a4582fca7181e32fa08d6e0bcb455d 337 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 30 57 1.1E-72 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_17320 c4a4582fca7181e32fa08d6e0bcb455d 337 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 6 196 1.2E-66 T 13-10-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_17320 c4a4582fca7181e32fa08d6e0bcb455d 337 Gene3D G3DSA:3.40.190.80 199 336 4.6E-51 T 13-10-2018 THITH_17320 c4a4582fca7181e32fa08d6e0bcb455d 337 PIRSF PIRSF000904 1 337 5.2E-123 T 13-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_17320 c4a4582fca7181e32fa08d6e0bcb455d 337 SUPERFAMILY SSF56655 5 335 3.52E-115 T 13-10-2018 THITH_17320 c4a4582fca7181e32fa08d6e0bcb455d 337 Gene3D G3DSA:3.30.540.10 2 198 6.5E-73 T 13-10-2018 THITH_17320 c4a4582fca7181e32fa08d6e0bcb455d 337 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 5 337 47.038 T 13-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_17320 c4a4582fca7181e32fa08d6e0bcb455d 337 PIRSF PIRSF500210 1 337 9.8E-125 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_08010 f73b41c410a6aa896d72143046bfa017 209 Gene3D G3DSA:3.40.430.10 1 208 4.2E-55 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 THITH_08010 f73b41c410a6aa896d72143046bfa017 209 SUPERFAMILY SSF53597 1 199 4.23E-48 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 THITH_08010 f73b41c410a6aa896d72143046bfa017 209 Pfam PF01872 RibD C-terminal domain 1 194 2.5E-39 T 13-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 THITH_10590 ea225b74808c6e8e0a211dcb08792f31 668 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 16 500 2.3E-67 T 13-10-2018 IPR005674 CocE/Serine esterase GO:0016787 THITH_10590 ea225b74808c6e8e0a211dcb08792f31 668 SMART SM00939 287 544 9.6E-75 T 13-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 THITH_10590 ea225b74808c6e8e0a211dcb08792f31 668 Gene3D G3DSA:1.10.3020.10 150 223 3.0E-61 T 13-10-2018 THITH_10590 ea225b74808c6e8e0a211dcb08792f31 668 SUPERFAMILY SSF49785 287 524 1.85E-53 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily THITH_10590 ea225b74808c6e8e0a211dcb08792f31 668 Gene3D G3DSA:2.60.120.260 342 527 2.1E-37 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily THITH_10590 ea225b74808c6e8e0a211dcb08792f31 668 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 19 270 8.6E-62 T 13-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 THITH_10590 ea225b74808c6e8e0a211dcb08792f31 668 Gene3D G3DSA:3.40.50.1820 15 310 3.0E-61 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_10590 ea225b74808c6e8e0a211dcb08792f31 668 SUPERFAMILY SSF53474 6 332 1.19E-73 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_10590 ea225b74808c6e8e0a211dcb08792f31 668 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 300 544 1.0E-50 T 13-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 THITH_07325 1fd8fbde95110dcabb48a36fa07f7223 392 SUPERFAMILY SSF55973 4 117 3.61E-32 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_07325 1fd8fbde95110dcabb48a36fa07f7223 392 Gene3D G3DSA:3.30.300.10 110 381 1.6E-156 T 13-10-2018 THITH_07325 1fd8fbde95110dcabb48a36fa07f7223 392 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 240 379 2.6E-65 T 13-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_07325 1fd8fbde95110dcabb48a36fa07f7223 392 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 389 1.0E-154 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_07325 1fd8fbde95110dcabb48a36fa07f7223 392 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 123 133 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_07325 1fd8fbde95110dcabb48a36fa07f7223 392 Gene3D G3DSA:3.30.300.10 6 240 1.6E-156 T 13-10-2018 THITH_07325 1fd8fbde95110dcabb48a36fa07f7223 392 SUPERFAMILY SSF55973 117 238 6.28E-42 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_07325 1fd8fbde95110dcabb48a36fa07f7223 392 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 390 49.858 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_07325 1fd8fbde95110dcabb48a36fa07f7223 392 PIRSF PIRSF000497 1 391 2.2E-151 T 13-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_07325 1fd8fbde95110dcabb48a36fa07f7223 392 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 266 274 - T 13-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_07325 1fd8fbde95110dcabb48a36fa07f7223 392 Gene3D G3DSA:3.30.300.10 12 277 1.6E-156 T 13-10-2018 THITH_07325 1fd8fbde95110dcabb48a36fa07f7223 392 Pfam PF02772 S-adenosylmethionine synthetase, central domain 122 238 1.3E-38 T 13-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_07325 1fd8fbde95110dcabb48a36fa07f7223 392 SUPERFAMILY SSF55973 240 390 1.49E-65 T 13-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_07325 1fd8fbde95110dcabb48a36fa07f7223 392 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 108 7.9E-30 T 13-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 THITH_16060 ae1c70d93dde000dde5bf2bf8f78bed5 150 Pfam PF14467 Domain of unknown function (DUF4426) 31 149 1.0E-39 T 13-10-2018 IPR025218 Domain of unknown function DUF4426 THITH_16060 ae1c70d93dde000dde5bf2bf8f78bed5 150 Gene3D G3DSA:2.60.40.3340 23 150 2.9E-32 T 13-10-2018 THITH_09505 710a840ad7cd9a226a90af8fdc94bc97 204 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 80 155 1.9E-6 T 13-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 THITH_09505 710a840ad7cd9a226a90af8fdc94bc97 204 SUPERFAMILY SSF56214 80 142 7.67E-10 T 13-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 THITH_09505 710a840ad7cd9a226a90af8fdc94bc97 204 SUPERFAMILY SSF56214 30 72 2.79E-12 T 13-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 THITH_09505 710a840ad7cd9a226a90af8fdc94bc97 204 Gene3D G3DSA:3.90.470.20 27 98 2.0E-17 T 13-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 THITH_09780 fe050ddfecad14befb56ce1c9043712c 165 SUPERFAMILY SSF46689 1 54 8.24E-9 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_09780 fe050ddfecad14befb56ce1c9043712c 165 Pfam PF01527 Transposase 3 55 5.2E-10 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 THITH_02965 fe050ddfecad14befb56ce1c9043712c 165 SUPERFAMILY SSF46689 1 54 8.24E-9 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_02965 fe050ddfecad14befb56ce1c9043712c 165 Pfam PF01527 Transposase 3 55 5.2E-10 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 THITH_13755 fe050ddfecad14befb56ce1c9043712c 165 SUPERFAMILY SSF46689 1 54 8.24E-9 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_13755 fe050ddfecad14befb56ce1c9043712c 165 Pfam PF01527 Transposase 3 55 5.2E-10 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 THITH_05160 fe050ddfecad14befb56ce1c9043712c 165 SUPERFAMILY SSF46689 1 54 8.24E-9 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_05160 fe050ddfecad14befb56ce1c9043712c 165 Pfam PF01527 Transposase 3 55 5.2E-10 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 THITH_09250 642d4aacd1f3265c060238e09e67305e 94 SUPERFAMILY SSF143430 7 79 3.27E-12 T 13-10-2018 THITH_09250 642d4aacd1f3265c060238e09e67305e 94 Pfam PF09827 CRISPR associated protein Cas2 7 71 2.9E-6 T 13-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 THITH_09250 642d4aacd1f3265c060238e09e67305e 94 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 5 92 10.708 T 13-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THITH_09250 642d4aacd1f3265c060238e09e67305e 94 Gene3D G3DSA:3.30.70.240 2 90 1.6E-12 T 13-10-2018 THITH_16740 ce8ca47c2d7726c8fb16044279170bf2 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 2.3E-7 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THITH_16740 ce8ca47c2d7726c8fb16044279170bf2 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 2.3E-7 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THITH_16740 ce8ca47c2d7726c8fb16044279170bf2 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 2.3E-7 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THITH_16740 ce8ca47c2d7726c8fb16044279170bf2 111 SMART SM00418 8 85 3.7E-14 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THITH_16740 ce8ca47c2d7726c8fb16044279170bf2 111 Pfam PF12840 Helix-turn-helix domain 10 68 1.7E-13 T 13-10-2018 THITH_16740 ce8ca47c2d7726c8fb16044279170bf2 111 Gene3D G3DSA:1.10.10.10 1 93 2.1E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_16740 ce8ca47c2d7726c8fb16044279170bf2 111 SUPERFAMILY SSF46785 1 93 7.75E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_07945 1176e7075b54c770f71ba58eb7cb3a47 360 Gene3D G3DSA:3.40.190.10 173 257 4.2E-61 T 13-10-2018 THITH_07945 1176e7075b54c770f71ba58eb7cb3a47 360 SMART SM00830 11 91 8.0E-33 T 13-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 THITH_07945 1176e7075b54c770f71ba58eb7cb3a47 360 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 305 312 - T 13-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 THITH_07945 1176e7075b54c770f71ba58eb7cb3a47 360 Pfam PF01842 ACT domain 279 343 5.8E-12 T 13-10-2018 IPR002912 ACT domain THITH_07945 1176e7075b54c770f71ba58eb7cb3a47 360 ProSitePatterns PS00857 Prephenate dehydratase signature 1. 243 265 - T 13-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 THITH_07945 1176e7075b54c770f71ba58eb7cb3a47 360 SUPERFAMILY SSF55021 262 357 2.47E-25 T 13-10-2018 THITH_07945 1176e7075b54c770f71ba58eb7cb3a47 360 Gene3D G3DSA:3.40.190.10 95 265 4.2E-61 T 13-10-2018 THITH_07945 1176e7075b54c770f71ba58eb7cb3a47 360 SUPERFAMILY SSF53850 92 274 1.3E-60 T 13-10-2018 THITH_07945 1176e7075b54c770f71ba58eb7cb3a47 360 Pfam PF01817 Chorismate mutase type II 11 89 1.0E-25 T 13-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 THITH_07945 1176e7075b54c770f71ba58eb7cb3a47 360 PIRSF PIRSF001500 2 360 1.2E-132 T 13-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 THITH_07945 1176e7075b54c770f71ba58eb7cb3a47 360 Gene3D G3DSA:3.30.70.260 271 359 4.4E-28 T 13-10-2018 THITH_07945 1176e7075b54c770f71ba58eb7cb3a47 360 Gene3D G3DSA:1.20.59.10 4 91 2.3E-31 T 13-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 THITH_07945 1176e7075b54c770f71ba58eb7cb3a47 360 SUPERFAMILY SSF48600 6 90 2.93E-22 T 13-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 THITH_07945 1176e7075b54c770f71ba58eb7cb3a47 360 Pfam PF00800 Prephenate dehydratase 93 267 1.6E-63 T 13-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 THITH_07945 1176e7075b54c770f71ba58eb7cb3a47 360 TIGRFAM TIGR01807 CM_P2: chorismate mutase 7 81 7.5E-27 T 13-10-2018 IPR010957 Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain GO:0004106|GO:0005737|GO:0009094 KEGG: 00400+5.4.99.5+4.2.1.51|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7432|MetaCyc: PWY-7626 THITH_04790 aa7d040a0e36e64277e16f876b2d71b9 150 SMART SM00091 8 77 0.0061 T 13-10-2018 IPR000014 PAS domain THITH_04790 aa7d040a0e36e64277e16f876b2d71b9 150 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 8 131 1.3E-21 T 13-10-2018 IPR000014 PAS domain THITH_04790 aa7d040a0e36e64277e16f876b2d71b9 150 SUPERFAMILY SSF55785 15 125 1.61E-30 T 13-10-2018 IPR035965 PAS domain superfamily THITH_04790 aa7d040a0e36e64277e16f876b2d71b9 150 Gene3D G3DSA:3.30.450.20 5 149 6.3E-52 T 13-10-2018 THITH_04790 aa7d040a0e36e64277e16f876b2d71b9 150 Pfam PF13426 PAS domain 19 124 5.9E-25 T 13-10-2018 IPR000014 PAS domain THITH_04790 aa7d040a0e36e64277e16f876b2d71b9 150 SMART SM00086 83 125 3.4E-15 T 13-10-2018 IPR001610 PAC motif THITH_03535 2c29135809174220bdeb08e5fc25a1fa 251 Hamap MF_01887 23S rRNA (guanosine-2'-O-)-methyltransferase RlmB [rlmB]. 4 244 39.99 T 13-10-2018 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB THITH_03535 2c29135809174220bdeb08e5fc25a1fa 251 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 7 79 7.0E-15 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 THITH_03535 2c29135809174220bdeb08e5fc25a1fa 251 SUPERFAMILY SSF75217 70 245 5.23E-48 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases THITH_03535 2c29135809174220bdeb08e5fc25a1fa 251 Pfam PF00588 SpoU rRNA Methylase family 97 236 9.4E-39 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 THITH_03535 2c29135809174220bdeb08e5fc25a1fa 251 Gene3D G3DSA:3.30.1330.30 1 78 1.8E-20 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like THITH_03535 2c29135809174220bdeb08e5fc25a1fa 251 SMART SM00967 6 82 4.1E-11 T 13-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 THITH_03535 2c29135809174220bdeb08e5fc25a1fa 251 Gene3D G3DSA:3.40.1280.10 80 244 1.1E-59 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THITH_03535 2c29135809174220bdeb08e5fc25a1fa 251 SUPERFAMILY SSF55315 5 78 8.59E-16 T 13-10-2018 IPR029064 50S ribosomal protein L30e-like THITH_03535 2c29135809174220bdeb08e5fc25a1fa 251 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 5 243 2.1E-71 T 13-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 THITH_15770 6bc8de70f5adaf5841b52cb57ff8ea5f 249 SUPERFAMILY SSF75169 161 248 7.42E-13 T 13-10-2018 IPR027396 DsrEFH-like THITH_15770 6bc8de70f5adaf5841b52cb57ff8ea5f 249 Gene3D G3DSA:3.40.1260.10 129 248 3.8E-17 T 13-10-2018 IPR027396 DsrEFH-like THITH_15835 62952c5530f3156a43b9bf5d1c4a1e18 270 Pfam PF02675 S-adenosylmethionine decarboxylase 40 174 5.1E-31 T 13-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 THITH_15835 62952c5530f3156a43b9bf5d1c4a1e18 270 SUPERFAMILY SSF56276 48 178 8.63E-24 T 13-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 THITH_15835 62952c5530f3156a43b9bf5d1c4a1e18 270 PIRSF PIRSF001356 3 268 5.0E-142 T 13-10-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 THITH_15835 62952c5530f3156a43b9bf5d1c4a1e18 270 TIGRFAM TIGR03331 SAM_DCase_Eco: S-adenosylmethionine decarboxylase proenzyme 8 266 6.8E-145 T 13-10-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 THITH_15835 62952c5530f3156a43b9bf5d1c4a1e18 270 Gene3D G3DSA:3.60.90.10 109 190 1.4E-6 T 13-10-2018 THITH_15835 62952c5530f3156a43b9bf5d1c4a1e18 270 Hamap MF_00465 S-adenosylmethionine decarboxylase proenzyme [speD]. 1 270 163.198 T 13-10-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 THITH_05940 88e9547238d6f55f8b750ca194499765 146 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 11 125 4.7E-13 T 13-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component THITH_05940 88e9547238d6f55f8b750ca194499765 146 SUPERFAMILY SSF88723 11 137 1.01E-13 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_05940 88e9547238d6f55f8b750ca194499765 146 Pfam PF13470 PIN domain 11 120 7.3E-23 T 13-10-2018 IPR002716 PIN domain THITH_13765 2532f89d9fa6321503d48417b51573c3 186 TIGRFAM TIGR02563 cas_Csy4: CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST 3 186 3.2E-52 T 13-10-2018 IPR013396 CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST GO:0004519|GO:0043571 THITH_13765 2532f89d9fa6321503d48417b51573c3 186 Pfam PF09618 CRISPR-associated protein (Cas_Csy4) 4 186 5.6E-62 T 13-10-2018 IPR013396 CRISPR-associated endoribonuclease Cas6/Csy4, subtype I-F/YPEST GO:0004519|GO:0043571 THITH_13765 2532f89d9fa6321503d48417b51573c3 186 Gene3D G3DSA:3.30.70.2540 1 186 3.5E-56 T 13-10-2018 THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 SUPERFAMILY SSF54211 231 486 3.49E-96 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 Gene3D G3DSA:3.30.565.10 1 226 3.4E-74 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 SMART SM00387 29 186 2.7E-8 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 Gene3D G3DSA:1.20.120.790 495 626 1.2E-35 T 13-10-2018 IPR037196 HSP90, C-terminal domain THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 PRINTS PR00775 90kDa heat shock protein signature 28 50 2.3E-57 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 PRINTS PR00775 90kDa heat shock protein signature 192 210 2.3E-57 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 PRINTS PR00775 90kDa heat shock protein signature 95 112 2.3E-57 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 PRINTS PR00775 90kDa heat shock protein signature 7 27 2.3E-57 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 PRINTS PR00775 90kDa heat shock protein signature 77 94 2.3E-57 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 PRINTS PR00775 90kDa heat shock protein signature 174 191 2.3E-57 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 PRINTS PR00775 90kDa heat shock protein signature 122 144 2.3E-57 T 13-10-2018 IPR020575 Heat shock protein Hsp90, N-terminal THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 SUPERFAMILY SSF55874 7 212 1.02E-64 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 Gene3D G3DSA:3.30.230.80 230 397 2.2E-68 T 13-10-2018 THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 Pfam PF00183 Hsp90 protein 221 626 8.4E-117 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 SUPERFAMILY SSF110942 515 626 3.79E-31 T 13-10-2018 IPR037196 HSP90, C-terminal domain THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 Gene3D G3DSA:3.40.50.11260 398 487 1.4E-29 T 13-10-2018 THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 Hamap MF_00505 Chaperone protein HtpG [htpG]. 4 626 31.468 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 PIRSF PIRSF002583 1 629 9.7E-203 T 13-10-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0051082 THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 156 1.1E-11 T 13-10-2018 THITH_02715 3852c43786d91dd4e6f0433c76bea1a5 629 ProSitePatterns PS00298 Heat shock hsp90 proteins family signature. 27 36 - T 13-10-2018 IPR019805 Heat shock protein Hsp90, conserved site GO:0005524|GO:0006457|GO:0051082 THITH_15075 e9eb713c44589a8f81bf033c7e8fe485 828 Pfam PF01464 Transglycosylase SLT domain 663 757 1.6E-18 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 THITH_15075 e9eb713c44589a8f81bf033c7e8fe485 828 Gene3D G3DSA:1.10.530.10 655 781 9.5E-26 T 13-10-2018 THITH_15075 e9eb713c44589a8f81bf033c7e8fe485 828 SUPERFAMILY SSF53955 653 758 6.75E-29 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily THITH_09060 3067a70791a4de501f6071754321bf82 214 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 184 197 - T 13-10-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 THITH_09060 3067a70791a4de501f6071754321bf82 214 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 46 118 1.2E-23 T 13-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 THITH_09060 3067a70791a4de501f6071754321bf82 214 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 12 214 36.296 T 13-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 THITH_09060 3067a70791a4de501f6071754321bf82 214 SUPERFAMILY SSF50475 17 214 1.33E-66 T 13-10-2018 THITH_09060 3067a70791a4de501f6071754321bf82 214 PIRSF PIRSF000190 1 214 6.4E-73 T 13-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 THITH_09060 3067a70791a4de501f6071754321bf82 214 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 174 214 8.4E-19 T 13-10-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 THITH_09060 3067a70791a4de501f6071754321bf82 214 Gene3D G3DSA:2.30.110.10 2 214 2.1E-79 T 13-10-2018 IPR012349 FMN-binding split barrel GO:0048037 THITH_09060 3067a70791a4de501f6071754321bf82 214 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 6 214 1.3E-74 T 13-10-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 THITH_10330 d9b03acb6766264df48569665c261a81 626 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 247 273 1.2E-62 T 13-10-2018 THITH_10330 d9b03acb6766264df48569665c261a81 626 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 225 246 1.2E-62 T 13-10-2018 THITH_10330 d9b03acb6766264df48569665c261a81 626 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 420 439 1.2E-62 T 13-10-2018 THITH_10330 d9b03acb6766264df48569665c261a81 626 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 111 131 1.2E-62 T 13-10-2018 THITH_10330 d9b03acb6766264df48569665c261a81 626 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 83 108 1.2E-62 T 13-10-2018 THITH_10330 d9b03acb6766264df48569665c261a81 626 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 315 327 1.2E-62 T 13-10-2018 THITH_10330 d9b03acb6766264df48569665c261a81 626 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 158 179 1.2E-62 T 13-10-2018 THITH_10330 d9b03acb6766264df48569665c261a81 626 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 65 122 6.1E-26 T 13-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10330 d9b03acb6766264df48569665c261a81 626 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 59 83 3.0E-14 T 13-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THITH_10330 d9b03acb6766264df48569665c261a81 626 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 265 287 3.0E-14 T 13-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THITH_10330 d9b03acb6766264df48569665c261a81 626 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 85 105 3.0E-14 T 13-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THITH_10330 d9b03acb6766264df48569665c261a81 626 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 419 441 3.0E-14 T 13-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 THITH_10330 d9b03acb6766264df48569665c261a81 626 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 4 622 5.0E-213 T 13-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10330 d9b03acb6766264df48569665c261a81 626 Pfam PF00361 Proton-conducting membrane transporter 136 427 2.9E-90 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_17230 f7c422cac81d1c4fa82adf876a628676 672 PIRSF PIRSF001589 1 668 9.9E-139 T 13-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THITH_17230 f7c422cac81d1c4fa82adf876a628676 672 Gene3D G3DSA:3.40.50.620 242 431 9.3E-37 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_17230 f7c422cac81d1c4fa82adf876a628676 672 Gene3D G3DSA:3.40.50.620 468 609 1.8E-21 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_17230 f7c422cac81d1c4fa82adf876a628676 672 SUPERFAMILY SSF56235 1 231 2.06E-58 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_17230 f7c422cac81d1c4fa82adf876a628676 672 Pfam PF13537 Glutamine amidotransferase domain 50 171 4.9E-38 T 13-10-2018 IPR017932 Glutamine amidotransferase type 2 domain THITH_17230 f7c422cac81d1c4fa82adf876a628676 672 Pfam PF00733 Asparagine synthase 254 626 9.8E-87 T 13-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 THITH_17230 f7c422cac81d1c4fa82adf876a628676 672 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 576 1.7E-124 T 13-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 THITH_17230 f7c422cac81d1c4fa82adf876a628676 672 SUPERFAMILY SSF52402 227 618 1.51E-66 T 13-10-2018 THITH_17230 f7c422cac81d1c4fa82adf876a628676 672 Gene3D G3DSA:3.60.20.10 2 192 3.6E-51 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_01675 bd4d9d6959c3f4e695d469ae036c0ba1 552 Gene3D G3DSA:2.30.40.10 5 523 1.9E-129 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 THITH_01675 bd4d9d6959c3f4e695d469ae036c0ba1 552 Pfam PF07969 Amidohydrolase family 45 548 1.4E-98 T 13-10-2018 IPR013108 Amidohydrolase 3 THITH_01675 bd4d9d6959c3f4e695d469ae036c0ba1 552 Gene3D G3DSA:3.10.310.70 75 192 1.9E-129 T 13-10-2018 THITH_01675 bd4d9d6959c3f4e695d469ae036c0ba1 552 Gene3D G3DSA:3.20.20.140 57 507 1.9E-129 T 13-10-2018 THITH_01675 bd4d9d6959c3f4e695d469ae036c0ba1 552 SUPERFAMILY SSF51556 56 508 3.3E-27 T 13-10-2018 IPR032466 Metal-dependent hydrolase THITH_01675 bd4d9d6959c3f4e695d469ae036c0ba1 552 SUPERFAMILY SSF51338 1 551 1.18E-22 T 13-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 THITH_00530 439f858042542c896bd594432bbd2251 442 Gene3D G3DSA:1.10.8.60 335 439 4.2E-35 T 13-10-2018 THITH_00530 439f858042542c896bd594432bbd2251 442 SMART SM01086 335 428 6.7E-19 T 13-10-2018 IPR019489 Clp ATPase, C-terminal THITH_00530 439f858042542c896bd594432bbd2251 442 Pfam PF07724 AAA domain (Cdc48 subfamily) 189 329 6.1E-40 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THITH_00530 439f858042542c896bd594432bbd2251 442 SUPERFAMILY SSF52540 4 440 1.8E-88 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00530 439f858042542c896bd594432bbd2251 442 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 53 136 7.5E-7 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THITH_00530 439f858042542c896bd594432bbd2251 442 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 442 42.736 T 13-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 THITH_00530 439f858042542c896bd594432bbd2251 442 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 4 442 2.3E-204 T 13-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 THITH_00530 439f858042542c896bd594432bbd2251 442 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 335 407 5.0E-5 T 13-10-2018 IPR019489 Clp ATPase, C-terminal THITH_00530 439f858042542c896bd594432bbd2251 442 SMART SM00382 49 332 2.8E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_04370 7c008f0575f6865c12807a51c82418d3 347 TIGRFAM TIGR01946 rnfD: electron transport complex, RnfABCDGE type, D subunit 8 341 7.6E-120 T 13-10-2018 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D GO:0016021|GO:0022900 THITH_04370 7c008f0575f6865c12807a51c82418d3 347 Hamap MF_00462 Ion-translocating oxidoreductase complex subunit D [rsxD]. 3 342 25.839 T 13-10-2018 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D GO:0016021|GO:0022900 THITH_04370 7c008f0575f6865c12807a51c82418d3 347 Pfam PF03116 NQR2, RnfD, RnfE family 5 340 9.4E-99 T 13-10-2018 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD GO:0016020|GO:0055085 THITH_06130 7a37ef2db87b7ce4183f15abe5d4a3a6 422 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 17 418 1.4E-162 T 13-10-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 KEGG: 00340+1.14.99.50|MetaCyc: PWY-7255 THITH_06130 7a37ef2db87b7ce4183f15abe5d4a3a6 422 Pfam PF03781 Sulfatase-modifying factor enzyme 1 336 418 4.6E-8 T 13-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THITH_06130 7a37ef2db87b7ce4183f15abe5d4a3a6 422 Pfam PF03781 Sulfatase-modifying factor enzyme 1 186 321 3.2E-25 T 13-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THITH_06130 7a37ef2db87b7ce4183f15abe5d4a3a6 422 Gene3D G3DSA:3.90.1580.10 327 422 2.5E-10 T 13-10-2018 THITH_06130 7a37ef2db87b7ce4183f15abe5d4a3a6 422 Gene3D G3DSA:3.90.1580.10 179 326 2.9E-28 T 13-10-2018 THITH_06130 7a37ef2db87b7ce4183f15abe5d4a3a6 422 SUPERFAMILY SSF56436 183 420 5.27E-65 T 13-10-2018 IPR016187 C-type lectin fold THITH_06130 7a37ef2db87b7ce4183f15abe5d4a3a6 422 Pfam PF12867 DinB superfamily 22 152 5.0E-9 T 13-10-2018 IPR024775 DinB-like domain THITH_02230 406143c5a7a26e3bdc5a7db33eac94e7 92 SUPERFAMILY SSF143011 1 91 2.22E-15 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_02230 406143c5a7a26e3bdc5a7db33eac94e7 92 Gene3D G3DSA:3.30.2310.20 4 92 4.3E-9 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_02230 406143c5a7a26e3bdc5a7db33eac94e7 92 Pfam PF15738 Bacterial toxin of type II toxin-antitoxin system, YafQ 7 91 7.1E-8 T 13-10-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin THITH_09190 c7add102788ab397ac78fc5b434d8592 145 SUPERFAMILY SSF49764 21 144 2.3E-30 T 13-10-2018 IPR008978 HSP20-like chaperone THITH_09190 c7add102788ab397ac78fc5b434d8592 145 Gene3D G3DSA:2.60.40.790 3 145 1.7E-29 T 13-10-2018 IPR008978 HSP20-like chaperone THITH_09190 c7add102788ab397ac78fc5b434d8592 145 Pfam PF00011 Hsp20/alpha crystallin family 47 145 2.3E-20 T 13-10-2018 IPR002068 Alpha crystallin/Hsp20 domain THITH_05655 bac018f072bd1afadba5e7dc48998c9c 446 Gene3D G3DSA:3.40.50.300 248 413 2.0E-6 T 13-10-2018 THITH_05655 bac018f072bd1afadba5e7dc48998c9c 446 Gene3D G3DSA:3.40.50.300 1 81 4.9E-5 T 13-10-2018 THITH_05655 bac018f072bd1afadba5e7dc48998c9c 446 SUPERFAMILY SSF52540 1 378 2.77E-11 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_05655 bac018f072bd1afadba5e7dc48998c9c 446 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 46 377 3.4E-30 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THITH_10585 0e2f4f2e2362b8e1f8d753731beff65d 432 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THITH_10585 0e2f4f2e2362b8e1f8d753731beff65d 432 Pfam PF13535 ATP-grasp domain 140 297 2.4E-7 T 13-10-2018 THITH_10585 0e2f4f2e2362b8e1f8d753731beff65d 432 SUPERFAMILY SSF56059 94 348 4.42E-30 T 13-10-2018 THITH_10585 0e2f4f2e2362b8e1f8d753731beff65d 432 Gene3D G3DSA:3.30.470.20 94 432 6.0E-33 T 13-10-2018 THITH_05820 cc455686443a12d7570c547066b0f43c 234 Gene3D G3DSA:3.40.50.1000 52 167 5.3E-25 T 13-10-2018 IPR023214 HAD superfamily THITH_05820 cc455686443a12d7570c547066b0f43c 234 Pfam PF12710 haloacid dehalogenase-like hydrolase 22 150 2.5E-16 T 13-10-2018 THITH_05820 cc455686443a12d7570c547066b0f43c 234 Gene3D G3DSA:1.20.1440.100 22 51 5.3E-25 T 13-10-2018 THITH_05820 cc455686443a12d7570c547066b0f43c 234 SUPERFAMILY SSF56784 42 160 2.36E-10 T 13-10-2018 IPR036412 HAD-like superfamily THITH_16890 12a17d40a65b64eec223d1e2fdce8ea4 644 Gene3D G3DSA:2.130.10.10 144 287 9.1E-9 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 THITH_16890 12a17d40a65b64eec223d1e2fdce8ea4 644 Gene3D G3DSA:2.130.10.10 295 458 2.9E-5 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 THITH_16890 12a17d40a65b64eec223d1e2fdce8ea4 644 SUPERFAMILY SSF110296 198 517 9.55E-22 T 13-10-2018 THITH_16890 12a17d40a65b64eec223d1e2fdce8ea4 644 SUPERFAMILY SSF63829 53 262 1.79E-11 T 13-10-2018 THITH_09320 823ed5bff1735a49b30b6b2d9b331407 94 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 5 86 6.5E-9 T 13-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THITH_09320 823ed5bff1735a49b30b6b2d9b331407 94 Pfam PF09827 CRISPR associated protein Cas2 6 71 2.7E-13 T 13-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 THITH_09320 823ed5bff1735a49b30b6b2d9b331407 94 SUPERFAMILY SSF143430 5 83 1.96E-19 T 13-10-2018 THITH_09320 823ed5bff1735a49b30b6b2d9b331407 94 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 5 91 13.607 T 13-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THITH_09320 823ed5bff1735a49b30b6b2d9b331407 94 Gene3D G3DSA:3.30.70.240 2 88 1.4E-19 T 13-10-2018 THITH_17145 364c6bd1dde6bb7b96327ca333d4fd77 211 Pfam PF02630 SCO1/SenC 43 183 1.7E-28 T 13-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_17145 364c6bd1dde6bb7b96327ca333d4fd77 211 Gene3D G3DSA:3.40.30.10 37 204 2.6E-40 T 13-10-2018 THITH_17145 364c6bd1dde6bb7b96327ca333d4fd77 211 SUPERFAMILY SSF52833 53 201 1.23E-37 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_08740 56951310552f3e6b0691f3efa7feefff 79 Pfam PF00550 Phosphopantetheine attachment site 6 73 2.0E-16 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain THITH_08740 56951310552f3e6b0691f3efa7feefff 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 1 76 3.6E-36 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 THITH_08740 56951310552f3e6b0691f3efa7feefff 79 SMART SM00823 Phosphopantetheine attachment site 5 63 0.0069 T 13-10-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 THITH_08740 56951310552f3e6b0691f3efa7feefff 79 Gene3D G3DSA:1.10.1200.10 1 75 4.8E-29 T 13-10-2018 IPR036736 ACP-like superfamily THITH_08740 56951310552f3e6b0691f3efa7feefff 79 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 13-10-2018 IPR006162 Phosphopantetheine attachment site THITH_08740 56951310552f3e6b0691f3efa7feefff 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 41 76 3.0E-12 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 THITH_08740 56951310552f3e6b0691f3efa7feefff 79 SUPERFAMILY SSF47336 2 77 1.7E-23 T 13-10-2018 IPR036736 ACP-like superfamily THITH_08740 56951310552f3e6b0691f3efa7feefff 79 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 22.413 T 13-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 THITH_03165 6456e1f056d3d9002a544e334ce32808 648 Gene3D G3DSA:3.40.50.300 384 577 3.4E-36 T 13-10-2018 THITH_03165 6456e1f056d3d9002a544e334ce32808 648 SUPERFAMILY SSF52540 410 613 9.57E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_03165 6456e1f056d3d9002a544e334ce32808 648 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 439 564 4.3E-23 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THITH_03165 6456e1f056d3d9002a544e334ce32808 648 SMART SM00382 434 566 1.8E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_17155 a7b452c8f2d61753309dac0a5bb60760 216 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 13 198 26.315 T 13-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 THITH_17155 a7b452c8f2d61753309dac0a5bb60760 216 SUPERFAMILY SSF52540 14 197 1.21E-33 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_17155 a7b452c8f2d61753309dac0a5bb60760 216 Pfam PF01926 50S ribosome-binding GTPase 27 147 1.2E-19 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_17155 a7b452c8f2d61753309dac0a5bb60760 216 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 8 192 3.2E-66 T 13-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 THITH_17155 a7b452c8f2d61753309dac0a5bb60760 216 Gene3D G3DSA:3.40.50.300 3 204 1.2E-51 T 13-10-2018 THITH_04280 c91ca8c50b9bcfce79707dde0515db60 295 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 88 273 2.2E-5 T 13-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 THITH_08745 82dd5af02d51d8b6ddca28e279ee6718 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 187 1.1E-6 T 13-10-2018 THITH_08745 82dd5af02d51d8b6ddca28e279ee6718 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THITH_08745 82dd5af02d51d8b6ddca28e279ee6718 245 Gene3D G3DSA:3.40.50.720 4 245 5.4E-81 T 13-10-2018 THITH_08745 82dd5af02d51d8b6ddca28e279ee6718 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 5.8E-48 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_08745 82dd5af02d51d8b6ddca28e279ee6718 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 5.8E-48 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_08745 82dd5af02d51d8b6ddca28e279ee6718 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 5.8E-48 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_08745 82dd5af02d51d8b6ddca28e279ee6718 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 5.8E-48 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_08745 82dd5af02d51d8b6ddca28e279ee6718 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 5.8E-48 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_08745 82dd5af02d51d8b6ddca28e279ee6718 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.8E-48 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_08745 82dd5af02d51d8b6ddca28e279ee6718 245 SUPERFAMILY SSF51735 8 244 3.42E-80 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_08745 82dd5af02d51d8b6ddca28e279ee6718 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 242 3.1E-64 T 13-10-2018 THITH_08745 82dd5af02d51d8b6ddca28e279ee6718 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.4E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_08745 82dd5af02d51d8b6ddca28e279ee6718 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 1.4E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_08745 82dd5af02d51d8b6ddca28e279ee6718 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.4E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_08745 82dd5af02d51d8b6ddca28e279ee6718 245 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 242 1.9E-96 T 13-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 78 343 3.4E-47 T 13-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 PRINTS PR01180 Arginine decarboxylase signature 172 193 7.6E-65 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 PRINTS PR01180 Arginine decarboxylase signature 536 557 7.6E-65 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 PRINTS PR01180 Arginine decarboxylase signature 458 479 7.6E-65 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 PRINTS PR01180 Arginine decarboxylase signature 483 508 7.6E-65 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 PRINTS PR01180 Arginine decarboxylase signature 92 106 7.6E-65 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 PRINTS PR01180 Arginine decarboxylase signature 196 218 7.6E-65 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 PRINTS PR01180 Arginine decarboxylase signature 323 340 7.6E-65 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 PRINTS PR01180 Arginine decarboxylase signature 68 83 7.6E-65 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 PRINTS PR01180 Arginine decarboxylase signature 146 161 7.6E-65 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 PIRSF PIRSF001336 1 627 1.8E-232 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 SUPERFAMILY SSF50621 452 554 6.28E-5 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 Gene3D G3DSA:1.20.58.930 366 454 2.0E-218 T 13-10-2018 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 Hamap MF_01417 Biosynthetic arginine decarboxylase [speA]. 4 627 39.839 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 Gene3D G3DSA:2.40.37.10 15 563 2.0E-218 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 536 549 7.8E-16 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 100 118 7.8E-16 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 239 252 7.8E-16 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 123 135 7.8E-16 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 333 352 7.8E-16 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 TIGRFAM TIGR01273 speA: arginine decarboxylase 6 626 2.8E-236 T 13-10-2018 IPR002985 Arginine decarboxylase GO:0006527|GO:0008295|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 SUPERFAMILY SSF51419 69 345 1.14E-62 T 13-10-2018 IPR029066 PLP-binding barrel THITH_15735 b8d02960c50b00b75c23c5ee3bbdf604 627 Gene3D G3DSA:3.20.20.10 69 348 2.0E-218 T 13-10-2018 IPR029066 PLP-binding barrel THITH_13655 8d8a3d2db3031719275dc04d264dc460 228 Gene3D G3DSA:3.40.30.10 2 89 4.6E-26 T 13-10-2018 THITH_13655 8d8a3d2db3031719275dc04d264dc460 228 Gene3D G3DSA:1.20.1050.10 90 207 2.6E-23 T 13-10-2018 THITH_13655 8d8a3d2db3031719275dc04d264dc460 228 SUPERFAMILY SSF47616 78 198 1.81E-27 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily THITH_13655 8d8a3d2db3031719275dc04d264dc460 228 Pfam PF13410 Glutathione S-transferase, C-terminal domain 118 183 4.1E-7 T 13-10-2018 THITH_13655 8d8a3d2db3031719275dc04d264dc460 228 SUPERFAMILY SSF52833 4 102 2.61E-25 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_13655 8d8a3d2db3031719275dc04d264dc460 228 Pfam PF13417 Glutathione S-transferase, N-terminal domain 6 78 4.7E-18 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THITH_06970 872143448a9cd4951697fd695aca7a01 384 SUPERFAMILY SSF53187 5 383 1.97E-55 T 13-10-2018 THITH_06970 872143448a9cd4951697fd695aca7a01 384 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 105 140 - T 13-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 THITH_06970 872143448a9cd4951697fd695aca7a01 384 SUPERFAMILY SSF55031 176 279 5.53E-17 T 13-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain THITH_06970 872143448a9cd4951697fd695aca7a01 384 TIGRFAM TIGR01892 AcOrn-deacetyl: acetylornithine deacetylase (ArgE) 11 379 9.3E-123 T 13-10-2018 IPR010169 Acetylornithine deacetylase ArgE GO:0005737|GO:0006526|GO:0008777 KEGG: 00220+3.5.1.16|MetaCyc: PWY-5154 THITH_06970 872143448a9cd4951697fd695aca7a01 384 Gene3D G3DSA:3.30.70.360 176 293 4.9E-101 T 13-10-2018 THITH_06970 872143448a9cd4951697fd695aca7a01 384 Pfam PF07687 Peptidase dimerisation domain 172 279 1.2E-19 T 13-10-2018 IPR011650 Peptidase M20, dimerisation domain THITH_06970 872143448a9cd4951697fd695aca7a01 384 Pfam PF01546 Peptidase family M20/M25/M40 72 381 5.9E-36 T 13-10-2018 IPR002933 Peptidase M20 GO:0016787 THITH_06970 872143448a9cd4951697fd695aca7a01 384 Gene3D G3DSA:3.40.630.10 16 370 4.9E-101 T 13-10-2018 THITH_00355 a21774aeeb6238f30381df1bf0e8e8d0 407 Gene3D G3DSA:3.40.50.2000 2 209 2.0E-26 T 13-10-2018 THITH_00355 a21774aeeb6238f30381df1bf0e8e8d0 407 Pfam PF13439 Glycosyltransferase Family 4 28 206 2.6E-19 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 THITH_00355 a21774aeeb6238f30381df1bf0e8e8d0 407 SUPERFAMILY SSF53756 29 403 3.82E-79 T 13-10-2018 THITH_00355 a21774aeeb6238f30381df1bf0e8e8d0 407 Gene3D G3DSA:3.40.50.2000 211 384 2.0E-47 T 13-10-2018 THITH_00355 a21774aeeb6238f30381df1bf0e8e8d0 407 Pfam PF00534 Glycosyl transferases group 1 218 380 8.4E-37 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 THITH_07010 64243ca4e4ed2bca2f2661a90b93bf72 673 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 306 477 1.3E-41 T 13-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 THITH_07010 64243ca4e4ed2bca2f2661a90b93bf72 673 Gene3D G3DSA:3.90.226.10 2 298 1.3E-69 T 13-10-2018 THITH_07010 64243ca4e4ed2bca2f2661a90b93bf72 673 Gene3D G3DSA:3.40.50.720 299 483 2.3E-47 T 13-10-2018 THITH_07010 64243ca4e4ed2bca2f2661a90b93bf72 673 Pfam PF00378 Enoyl-CoA hydratase/isomerase 14 211 2.4E-34 T 13-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 THITH_07010 64243ca4e4ed2bca2f2661a90b93bf72 673 SUPERFAMILY SSF52096 3 293 9.36E-59 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THITH_07010 64243ca4e4ed2bca2f2661a90b93bf72 673 SUPERFAMILY SSF51735 303 479 1.65E-37 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_07010 64243ca4e4ed2bca2f2661a90b93bf72 673 SUPERFAMILY SSF48179 587 663 1.96E-15 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THITH_07010 64243ca4e4ed2bca2f2661a90b93bf72 673 SUPERFAMILY SSF48179 480 599 5.27E-30 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THITH_07010 64243ca4e4ed2bca2f2661a90b93bf72 673 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 478 503 - T 13-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 THITH_07010 64243ca4e4ed2bca2f2661a90b93bf72 673 Gene3D G3DSA:1.10.1040.50 484 666 2.0E-55 T 13-10-2018 THITH_07010 64243ca4e4ed2bca2f2661a90b93bf72 673 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 481 571 2.2E-24 T 13-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 THITH_14260 07e6bf20f3fac53c7862244e54ada1a2 225 SUPERFAMILY SSF54821 111 209 5.75E-40 T 13-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14260 07e6bf20f3fac53c7862244e54ada1a2 225 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 211 5.0E-92 T 13-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 THITH_14260 07e6bf20f3fac53c7862244e54ada1a2 225 Pfam PF07650 KH domain 38 113 2.9E-19 T 13-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14260 07e6bf20f3fac53c7862244e54ada1a2 225 Pfam PF00189 Ribosomal protein S3, C-terminal domain 123 205 1.3E-40 T 13-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14260 07e6bf20f3fac53c7862244e54ada1a2 225 Gene3D G3DSA:3.30.1140.32 111 211 1.2E-43 T 13-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14260 07e6bf20f3fac53c7862244e54ada1a2 225 Gene3D G3DSA:3.30.300.20 17 110 4.3E-24 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta THITH_14260 07e6bf20f3fac53c7862244e54ada1a2 225 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 209 38.447 T 13-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 THITH_14260 07e6bf20f3fac53c7862244e54ada1a2 225 SMART SM00322 60 128 4.0E-6 T 13-10-2018 IPR004087 K Homology domain GO:0003676 THITH_14260 07e6bf20f3fac53c7862244e54ada1a2 225 SUPERFAMILY SSF54814 2 109 3.4E-32 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 THITH_14260 07e6bf20f3fac53c7862244e54ada1a2 225 ProSitePatterns PS00548 Ribosomal protein S3 signature. 166 200 - T 13-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_11520 2081ff9142c22e6c85c04323fa817200 219 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 3 217 32.199 T 13-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 THITH_11520 2081ff9142c22e6c85c04323fa817200 219 SUPERFAMILY SSF75445 127 198 7.19E-23 T 13-10-2018 THITH_11520 2081ff9142c22e6c85c04323fa817200 219 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 49 213 5.6E-54 T 13-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 THITH_11520 2081ff9142c22e6c85c04323fa817200 219 Gene3D G3DSA:3.40.50.1360 7 207 7.1E-72 T 13-10-2018 THITH_11520 2081ff9142c22e6c85c04323fa817200 219 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 214 1.7E-63 T 13-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 THITH_11520 2081ff9142c22e6c85c04323fa817200 219 SUPERFAMILY SSF100950 1 145 1.3E-44 T 13-10-2018 IPR037171 NagB/RpiA transferase-like THITH_11520 2081ff9142c22e6c85c04323fa817200 219 Gene3D G3DSA:3.30.70.260 125 196 7.1E-72 T 13-10-2018 THITH_15270 456d22a2bfe394e677c780f1997747af 551 Hamap MF_00600 60 kDa chaperonin [groL]. 2 548 41.532 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THITH_15270 456d22a2bfe394e677c780f1997747af 551 Gene3D G3DSA:3.30.260.10 138 410 7.7E-238 T 13-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily THITH_15270 456d22a2bfe394e677c780f1997747af 551 SUPERFAMILY SSF54849 137 203 1.12E-23 T 13-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily THITH_15270 456d22a2bfe394e677c780f1997747af 551 Pfam PF00118 TCP-1/cpn60 chaperonin family 23 522 7.9E-93 T 13-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 THITH_15270 456d22a2bfe394e677c780f1997747af 551 PRINTS PR00298 60kDa chaperonin signature 27 53 8.2E-75 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THITH_15270 456d22a2bfe394e677c780f1997747af 551 PRINTS PR00298 60kDa chaperonin signature 83 110 8.2E-75 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THITH_15270 456d22a2bfe394e677c780f1997747af 551 PRINTS PR00298 60kDa chaperonin signature 398 419 8.2E-75 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THITH_15270 456d22a2bfe394e677c780f1997747af 551 PRINTS PR00298 60kDa chaperonin signature 350 375 8.2E-75 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THITH_15270 456d22a2bfe394e677c780f1997747af 551 PRINTS PR00298 60kDa chaperonin signature 268 291 8.2E-75 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THITH_15270 456d22a2bfe394e677c780f1997747af 551 SUPERFAMILY SSF48592 7 521 3.89E-75 T 13-10-2018 IPR027413 GroEL-like equatorial domain superfamily THITH_15270 456d22a2bfe394e677c780f1997747af 551 SUPERFAMILY SSF52029 185 376 8.9E-84 T 13-10-2018 IPR027409 GroEL-like apical domain superfamily THITH_15270 456d22a2bfe394e677c780f1997747af 551 TIGRFAM TIGR02348 GroEL: chaperonin GroL 3 527 3.6E-257 T 13-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THITH_15270 456d22a2bfe394e677c780f1997747af 551 Gene3D G3DSA:1.10.560.10 8 521 7.7E-238 T 13-10-2018 IPR027413 GroEL-like equatorial domain superfamily THITH_15270 456d22a2bfe394e677c780f1997747af 551 Gene3D G3DSA:3.50.7.10 173 379 7.7E-238 T 13-10-2018 IPR027409 GroEL-like apical domain superfamily THITH_15270 456d22a2bfe394e677c780f1997747af 551 ProSitePatterns PS00296 Chaperonins cpn60 signature. 405 416 - T 13-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 THITH_14160 959635095e45b4525f34463ce907bb66 125 Gene3D G3DSA:3.90.1030.10 1 117 7.7E-46 T 13-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14160 959635095e45b4525f34463ce907bb66 125 SUPERFAMILY SSF64263 1 119 3.01E-49 T 13-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14160 959635095e45b4525f34463ce907bb66 125 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14160 959635095e45b4525f34463ce907bb66 125 Pfam PF01196 Ribosomal protein L17 21 116 3.7E-33 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14160 959635095e45b4525f34463ce907bb66 125 TIGRFAM TIGR00059 L17: ribosomal protein bL17 8 117 9.6E-47 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14160 959635095e45b4525f34463ce907bb66 125 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 25.933 T 13-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_15950 614a889d2886981c9349065354543b2b 665 SMART SM00861 355 527 3.3E-65 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THITH_15950 614a889d2886981c9349065354543b2b 665 SUPERFAMILY SSF52518 5 330 2.95E-120 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold THITH_15950 614a889d2886981c9349065354543b2b 665 TIGRFAM TIGR00232 tktlase_bact: transketolase 6 665 3.6E-300 T 13-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 THITH_15950 614a889d2886981c9349065354543b2b 665 Pfam PF02779 Transketolase, pyrimidine binding domain 354 524 3.1E-44 T 13-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain THITH_15950 614a889d2886981c9349065354543b2b 665 ProSitePatterns PS00802 Transketolase signature 2. 468 484 - T 13-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THITH_15950 614a889d2886981c9349065354543b2b 665 SUPERFAMILY SSF52518 346 526 4.53E-66 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold THITH_15950 614a889d2886981c9349065354543b2b 665 Gene3D G3DSA:3.40.50.970 3 326 1.8E-132 T 13-10-2018 THITH_15950 614a889d2886981c9349065354543b2b 665 Gene3D G3DSA:3.40.50.970 327 538 5.5E-80 T 13-10-2018 THITH_15950 614a889d2886981c9349065354543b2b 665 SUPERFAMILY SSF52922 534 665 9.82E-44 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 THITH_15950 614a889d2886981c9349065354543b2b 665 Gene3D G3DSA:3.40.50.920 539 665 5.7E-42 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 THITH_15950 614a889d2886981c9349065354543b2b 665 Pfam PF02780 Transketolase, C-terminal domain 541 656 1.3E-13 T 13-10-2018 IPR033248 Transketolase, C-terminal domain THITH_15950 614a889d2886981c9349065354543b2b 665 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 4 334 5.7E-167 T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THITH_15950 614a889d2886981c9349065354543b2b 665 ProSitePatterns PS00801 Transketolase signature 1. 12 32 - T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THITH_03175 93ee29df2c8f0849ee07d1378615e8ac 326 Gene3D G3DSA:1.25.40.10 240 317 2.8E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_03175 93ee29df2c8f0849ee07d1378615e8ac 326 Gene3D G3DSA:1.25.40.10 6 152 4.5E-32 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_03175 93ee29df2c8f0849ee07d1378615e8ac 326 SMART SM00028 38 71 5.0E-5 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_03175 93ee29df2c8f0849ee07d1378615e8ac 326 SMART SM00028 106 139 12.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_03175 93ee29df2c8f0849ee07d1378615e8ac 326 SMART SM00028 72 105 14.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_03175 93ee29df2c8f0849ee07d1378615e8ac 326 SMART SM00028 174 207 0.0078 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_03175 93ee29df2c8f0849ee07d1378615e8ac 326 SMART SM00028 208 241 130.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_03175 93ee29df2c8f0849ee07d1378615e8ac 326 SMART SM00028 4 37 26.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_03175 93ee29df2c8f0849ee07d1378615e8ac 326 SMART SM00028 140 173 14.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_03175 93ee29df2c8f0849ee07d1378615e8ac 326 Pfam PF13414 TPR repeat 17 51 4.3E-9 T 13-10-2018 THITH_03175 93ee29df2c8f0849ee07d1378615e8ac 326 Pfam PF07721 Tetratricopeptide repeat 245 267 0.033 T 13-10-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 THITH_03175 93ee29df2c8f0849ee07d1378615e8ac 326 Pfam PF13432 Tetratricopeptide repeat 156 207 3.4E-6 T 13-10-2018 THITH_03175 93ee29df2c8f0849ee07d1378615e8ac 326 Pfam PF13432 Tetratricopeptide repeat 77 140 1.5E-6 T 13-10-2018 THITH_03175 93ee29df2c8f0849ee07d1378615e8ac 326 Gene3D G3DSA:1.25.40.10 153 239 3.3E-15 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_03175 93ee29df2c8f0849ee07d1378615e8ac 326 SUPERFAMILY SSF48452 12 304 2.9E-39 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_15540 6b6533f76109adfe71b523f5fe51c5ec 345 Gene3D G3DSA:1.40.20.10 8 266 1.7E-37 T 13-10-2018 IPR038186 CHAD domain superfamily THITH_15540 6b6533f76109adfe71b523f5fe51c5ec 345 SMART SM00880 20 277 5.8E-25 T 13-10-2018 IPR007899 CHAD domain THITH_15540 6b6533f76109adfe71b523f5fe51c5ec 345 Pfam PF05235 CHAD domain 36 243 1.6E-33 T 13-10-2018 IPR007899 CHAD domain THITH_11395 aa39a5af7b78616db04d71127bc9cd82 498 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 1 481 55.047 T 13-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 THITH_11395 aa39a5af7b78616db04d71127bc9cd82 498 Pfam PF02347 Glycine cleavage system P-protein 24 388 2.6E-12 T 13-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 THITH_11395 aa39a5af7b78616db04d71127bc9cd82 498 SUPERFAMILY SSF53383 19 476 2.11E-110 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_11395 aa39a5af7b78616db04d71127bc9cd82 498 Gene3D G3DSA:3.90.1150.10 331 466 1.5E-38 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_11395 aa39a5af7b78616db04d71127bc9cd82 498 Gene3D G3DSA:3.40.640.10 76 310 1.8E-58 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_06290 a7c84356b10ce17faf61ad362947d9c0 439 SUPERFAMILY SSF54534 183 283 5.23E-24 T 13-10-2018 THITH_06290 a7c84356b10ce17faf61ad362947d9c0 439 Gene3D G3DSA:3.10.50.40 289 427 1.6E-41 T 13-10-2018 THITH_06290 a7c84356b10ce17faf61ad362947d9c0 439 SUPERFAMILY SSF54534 292 391 6.41E-32 T 13-10-2018 THITH_06290 a7c84356b10ce17faf61ad362947d9c0 439 Gene3D G3DSA:3.10.50.40 181 283 3.4E-71 T 13-10-2018 THITH_06290 a7c84356b10ce17faf61ad362947d9c0 439 Pfam PF13616 PPIC-type PPIASE domain 290 390 3.0E-28 T 13-10-2018 THITH_06290 a7c84356b10ce17faf61ad362947d9c0 439 Hamap MF_01183 Chaperone SurA [surA]. 12 435 33.404 T 13-10-2018 IPR023034 Peptidyl-prolyl isomerase SurA GO:0003755|GO:0006457|GO:0030288|GO:0042277|GO:0043165|GO:0050821|GO:0051082|GO:0060274 THITH_06290 a7c84356b10ce17faf61ad362947d9c0 439 SUPERFAMILY SSF109998 35 208 7.06E-38 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily THITH_06290 a7c84356b10ce17faf61ad362947d9c0 439 Pfam PF09312 SurA N-terminal domain 34 151 3.6E-39 T 13-10-2018 IPR015391 SurA N-terminal THITH_06290 a7c84356b10ce17faf61ad362947d9c0 439 Gene3D G3DSA:1.10.4030.30 35 288 3.4E-71 T 13-10-2018 THITH_06290 a7c84356b10ce17faf61ad362947d9c0 439 Pfam PF00639 PPIC-type PPIASE domain 187 281 1.7E-18 T 13-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 THITH_06290 a7c84356b10ce17faf61ad362947d9c0 439 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 328 349 - T 13-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 THITH_00340 c40e17f0e4b622515e5feda06c62b40d 76 ProDom PD030562 SUPPRESSOR HTRA PROTEASE TRANSCRIPTIONAL REGULATOR HTAR SOHA ABRB YDCA BLL1688 5 63 0.001 T 13-10-2018 THITH_00340 c40e17f0e4b622515e5feda06c62b40d 76 Pfam PF15937 prlF antitoxin for toxin YhaV_toxin 5 47 1.7E-9 T 13-10-2018 IPR031848 PrlF antitoxin GO:0001558|GO:0003700|GO:0097351 THITH_00340 c40e17f0e4b622515e5feda06c62b40d 76 Gene3D G3DSA:2.10.260.10 2 41 1.9E-10 T 13-10-2018 THITH_00340 c40e17f0e4b622515e5feda06c62b40d 76 SUPERFAMILY SSF89447 3 39 1.92E-8 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily THITH_00340 c40e17f0e4b622515e5feda06c62b40d 76 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 5 31 8.4E-8 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THITH_00340 c40e17f0e4b622515e5feda06c62b40d 76 SMART SM00966 5 51 9.5E-7 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THITH_06250 c54029cc448f7ef16180267f901ecccd 99 SMART SM00411 4 93 2.1E-41 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THITH_06250 c54029cc448f7ef16180267f901ecccd 99 Pfam PF00216 Bacterial DNA-binding protein 4 92 9.2E-30 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THITH_06250 c54029cc448f7ef16180267f901ecccd 99 PRINTS PR01727 Prokaryotic integration host factor signature 43 58 8.8E-17 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THITH_06250 c54029cc448f7ef16180267f901ecccd 99 PRINTS PR01727 Prokaryotic integration host factor signature 61 74 8.8E-17 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THITH_06250 c54029cc448f7ef16180267f901ecccd 99 PRINTS PR01727 Prokaryotic integration host factor signature 77 91 8.8E-17 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THITH_06250 c54029cc448f7ef16180267f901ecccd 99 TIGRFAM TIGR00987 himA: integration host factor, alpha subunit 3 97 9.3E-47 T 13-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 THITH_06250 c54029cc448f7ef16180267f901ecccd 99 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 49 68 - T 13-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 THITH_06250 c54029cc448f7ef16180267f901ecccd 99 Gene3D G3DSA:4.10.520.10 2 98 3.0E-35 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 THITH_06250 c54029cc448f7ef16180267f901ecccd 99 SUPERFAMILY SSF47729 4 93 1.47E-30 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 THITH_06250 c54029cc448f7ef16180267f901ecccd 99 Hamap MF_00380 Integration host factor subunit alpha [ihfA]. 2 98 30.242 T 13-10-2018 IPR005684 Integration host factor, alpha subunit GO:0003677|GO:0006310|GO:0006355 THITH_15490 a90e5aeac94fe44c83279ad5f7800280 267 Pfam PF03649 Uncharacterised protein family (UPF0014) 9 251 1.6E-83 T 13-10-2018 IPR005226 UPF0014 family THITH_15490 a90e5aeac94fe44c83279ad5f7800280 267 TIGRFAM TIGR00245 TIGR00245: TIGR00245 family protein 8 256 3.3E-54 T 13-10-2018 IPR005226 UPF0014 family THITH_14950 d2da5d29ba43c5f858c647aa116ebf56 293 SUPERFAMILY SSF53807 41 284 7.06E-58 T 13-10-2018 THITH_14950 d2da5d29ba43c5f858c647aa116ebf56 293 Gene3D G3DSA:3.40.50.1980 163 288 4.6E-24 T 13-10-2018 THITH_14950 d2da5d29ba43c5f858c647aa116ebf56 293 Pfam PF01497 Periplasmic binding protein 45 241 1.0E-24 T 13-10-2018 IPR002491 ABC transporter periplasmic binding domain THITH_14950 d2da5d29ba43c5f858c647aa116ebf56 293 Gene3D G3DSA:3.40.50.1980 42 161 2.5E-37 T 13-10-2018 THITH_09565 44465ef0b50d1808591c03bc37eb133d 205 Pfam PF01300 Telomere recombination 22 197 6.7E-42 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 THITH_09565 44465ef0b50d1808591c03bc37eb133d 205 Gene3D G3DSA:3.90.870.10 1 203 3.6E-61 T 13-10-2018 THITH_09565 44465ef0b50d1808591c03bc37eb133d 205 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 6 199 5.3E-56 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 THITH_09565 44465ef0b50d1808591c03bc37eb133d 205 SUPERFAMILY SSF55821 4 202 2.66E-59 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily THITH_11555 f35dcdbbcd8ac1c7ab52a4a2c94911a2 141 Gene3D G3DSA:1.10.10.60 18 125 9.8E-25 T 13-10-2018 THITH_11555 f35dcdbbcd8ac1c7ab52a4a2c94911a2 141 SUPERFAMILY SSF46689 21 71 7.77E-10 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_11555 f35dcdbbcd8ac1c7ab52a4a2c94911a2 141 SUPERFAMILY SSF46689 76 122 2.46E-9 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_11555 f35dcdbbcd8ac1c7ab52a4a2c94911a2 141 SMART SM00342 38 121 3.4E-20 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THITH_11555 f35dcdbbcd8ac1c7ab52a4a2c94911a2 141 Pfam PF12833 Helix-turn-helix domain 44 122 5.9E-18 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THITH_05265 d5578cc9c646252105ef9f32efec0899 462 SUPERFAMILY SSF56601 6 339 5.63E-76 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like THITH_05265 d5578cc9c646252105ef9f32efec0899 462 Pfam PF00144 Beta-lactamase 12 330 1.1E-64 T 13-10-2018 IPR001466 Beta-lactamase-related THITH_05265 d5578cc9c646252105ef9f32efec0899 462 Gene3D G3DSA:3.40.710.10 3 342 4.3E-78 T 13-10-2018 THITH_07150 f94e8dcdff9bb65ea49d7763fb9067f0 459 SUPERFAMILY SSF116726 136 223 6.28E-11 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_07150 f94e8dcdff9bb65ea49d7763fb9067f0 459 Pfam PF02080 TrkA-C domain 156 225 1.6E-10 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THITH_07150 f94e8dcdff9bb65ea49d7763fb9067f0 459 Pfam PF02080 TrkA-C domain 392 452 1.3E-8 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THITH_07150 f94e8dcdff9bb65ea49d7763fb9067f0 459 SUPERFAMILY SSF116726 391 453 1.96E-8 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_07150 f94e8dcdff9bb65ea49d7763fb9067f0 459 SUPERFAMILY SSF51735 2 152 4.79E-34 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_07150 f94e8dcdff9bb65ea49d7763fb9067f0 459 Gene3D G3DSA:3.40.50.720 3 139 2.9E-43 T 13-10-2018 THITH_07150 f94e8dcdff9bb65ea49d7763fb9067f0 459 Gene3D G3DSA:3.30.70.1450 369 459 1.7E-25 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_07150 f94e8dcdff9bb65ea49d7763fb9067f0 459 SUPERFAMILY SSF51735 232 377 2.49E-29 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_07150 f94e8dcdff9bb65ea49d7763fb9067f0 459 PRINTS PR00335 TrkA potassium uptake protein signature 61 71 5.1E-22 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THITH_07150 f94e8dcdff9bb65ea49d7763fb9067f0 459 PRINTS PR00335 TrkA potassium uptake protein signature 50 60 5.1E-22 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THITH_07150 f94e8dcdff9bb65ea49d7763fb9067f0 459 PRINTS PR00335 TrkA potassium uptake protein signature 74 88 5.1E-22 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THITH_07150 f94e8dcdff9bb65ea49d7763fb9067f0 459 PRINTS PR00335 TrkA potassium uptake protein signature 3 17 5.1E-22 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THITH_07150 f94e8dcdff9bb65ea49d7763fb9067f0 459 PRINTS PR00335 TrkA potassium uptake protein signature 20 34 5.1E-22 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THITH_07150 f94e8dcdff9bb65ea49d7763fb9067f0 459 Pfam PF02254 TrkA-N domain 235 351 7.3E-25 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 THITH_07150 f94e8dcdff9bb65ea49d7763fb9067f0 459 Pfam PF02254 TrkA-N domain 4 108 1.1E-25 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 THITH_07150 f94e8dcdff9bb65ea49d7763fb9067f0 459 Gene3D G3DSA:3.30.70.1450 140 232 2.1E-20 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_07150 f94e8dcdff9bb65ea49d7763fb9067f0 459 Gene3D G3DSA:3.40.50.720 233 367 1.1E-33 T 13-10-2018 THITH_16070 b2de66955d19506291b76bd93a982b22 103 SUPERFAMILY SSF141255 4 93 1.57E-19 T 13-10-2018 IPR036623 Hemimethylated DNA-binding domain superfamily GO:0003677 THITH_16070 b2de66955d19506291b76bd93a982b22 103 TIGRFAM TIGR02097 yccV: hemimethylated DNA binding domain 3 98 3.3E-20 T 13-10-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 THITH_16070 b2de66955d19506291b76bd93a982b22 103 SMART SM00992 3 99 3.5E-18 T 13-10-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 THITH_16070 b2de66955d19506291b76bd93a982b22 103 Gene3D G3DSA:2.30.30.390 1 101 8.4E-22 T 13-10-2018 IPR036623 Hemimethylated DNA-binding domain superfamily GO:0003677 THITH_16070 b2de66955d19506291b76bd93a982b22 103 Pfam PF08755 Hemimethylated DNA-binding protein YccV like 5 93 2.3E-18 T 13-10-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 644 9.8E-224 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 Pfam PF01578 Cytochrome C assembly protein 89 295 6.8E-52 T 13-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 1.2E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 313 328 1.2E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 189 204 1.2E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 634 647 1.2E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 394 413 1.2E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 351 368 1.2E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 1.2E-56 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 641 7.2E-124 T 13-10-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 3.3E-88 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 3.3E-88 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 3.3E-88 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 3.3E-88 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 3.3E-88 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 3.3E-88 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 3.3E-88 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16165 8eb96aab1e5b28b0cd615eb6fd4345b0 669 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 3.3E-88 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_15520 7c5e65777e7d230e229b56a51d3087ce 117 SUPERFAMILY SSF55620 1 115 4.82E-31 T 13-10-2018 THITH_15520 7c5e65777e7d230e229b56a51d3087ce 117 TIGRFAM TIGR00526 folB_dom: FolB domain 1 115 4.0E-23 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 THITH_15520 7c5e65777e7d230e229b56a51d3087ce 117 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 2 114 2.7E-23 T 13-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 THITH_15520 7c5e65777e7d230e229b56a51d3087ce 117 SMART SM00905 4 114 4.9E-36 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 THITH_15520 7c5e65777e7d230e229b56a51d3087ce 117 Gene3D G3DSA:3.30.1130.10 1 116 1.2E-34 T 13-10-2018 THITH_15520 7c5e65777e7d230e229b56a51d3087ce 117 Pfam PF02152 Dihydroneopterin aldolase 4 113 1.0E-27 T 13-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 THITH_00800 54c85f088f1f3444c1891b985a42bd3c 188 Gene3D G3DSA:1.10.10.10 105 173 9.8E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_00800 54c85f088f1f3444c1891b985a42bd3c 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 168 1.6E-24 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 THITH_00800 54c85f088f1f3444c1891b985a42bd3c 188 SUPERFAMILY SSF88946 2 78 2.12E-17 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 THITH_00800 54c85f088f1f3444c1891b985a42bd3c 188 Pfam PF08281 Sigma-70, region 4 111 163 3.7E-14 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THITH_00800 54c85f088f1f3444c1891b985a42bd3c 188 SUPERFAMILY SSF88659 100 168 6.92E-16 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like THITH_00800 54c85f088f1f3444c1891b985a42bd3c 188 Pfam PF04542 Sigma-70 region 2 2 62 4.0E-13 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 THITH_00800 54c85f088f1f3444c1891b985a42bd3c 188 Gene3D G3DSA:1.10.1740.10 1 66 2.4E-20 T 13-10-2018 THITH_00735 4c3b87ddea24003876aa15b269c7bfae 1184 Gene3D G3DSA:1.10.10.160 96 211 3.0E-118 T 13-10-2018 IPR013986 DExx box DNA helicase domain superfamily THITH_00735 4c3b87ddea24003876aa15b269c7bfae 1184 PIRSF PIRSF000980 10 1183 0.0 T 13-10-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 THITH_00735 4c3b87ddea24003876aa15b269c7bfae 1184 Gene3D G3DSA:3.40.50.300 358 832 1.3E-192 T 13-10-2018 THITH_00735 4c3b87ddea24003876aa15b269c7bfae 1184 SUPERFAMILY SSF52980 864 1175 4.29E-57 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_00735 4c3b87ddea24003876aa15b269c7bfae 1184 Gene3D G3DSA:1.10.486.10 474 687 1.3E-192 T 13-10-2018 THITH_00735 4c3b87ddea24003876aa15b269c7bfae 1184 TIGRFAM TIGR01450 recC: exodeoxyribonuclease V, gamma subunit 11 1140 0.0 T 13-10-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 THITH_00735 4c3b87ddea24003876aa15b269c7bfae 1184 SUPERFAMILY SSF52540 385 838 1.17E-97 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00735 4c3b87ddea24003876aa15b269c7bfae 1184 SUPERFAMILY SSF52540 10 370 5.11E-101 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00735 4c3b87ddea24003876aa15b269c7bfae 1184 Pfam PF04257 Exodeoxyribonuclease V, gamma subunit 11 832 2.7E-281 T 13-10-2018 THITH_00735 4c3b87ddea24003876aa15b269c7bfae 1184 Gene3D G3DSA:3.40.50.10930 13 327 3.0E-118 T 13-10-2018 THITH_00735 4c3b87ddea24003876aa15b269c7bfae 1184 Hamap MF_01486 RecBCD enzyme subunit RecC [recC]. 10 1179 20.116 T 13-10-2018 IPR006697 RecBCD enzyme subunit RecC GO:0008854|GO:0009338 THITH_14265 344c08e67f3771e7f553f6b51e2f00e3 116 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 4 113 28.259 T 13-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14265 344c08e67f3771e7f553f6b51e2f00e3 116 Pfam PF00237 Ribosomal protein L22p/L17e 8 109 5.0E-38 T 13-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 THITH_14265 344c08e67f3771e7f553f6b51e2f00e3 116 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 8 110 4.5E-47 T 13-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14265 344c08e67f3771e7f553f6b51e2f00e3 116 Gene3D G3DSA:3.90.470.10 2 116 6.6E-45 T 13-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 THITH_14265 344c08e67f3771e7f553f6b51e2f00e3 116 SUPERFAMILY SSF54843 4 113 1.83E-42 T 13-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 THITH_14265 344c08e67f3771e7f553f6b51e2f00e3 116 ProSitePatterns PS00464 Ribosomal protein L22 signature. 86 110 - T 13-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14925 b63f360507b7d32472ad0ee14a8adcea 365 Pfam PF01761 3-dehydroquinate synthase 65 323 2.5E-108 T 13-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 THITH_14925 b63f360507b7d32472ad0ee14a8adcea 365 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 13 349 3.3E-118 T 13-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 THITH_14925 b63f360507b7d32472ad0ee14a8adcea 365 Gene3D G3DSA:3.40.50.1970 1 170 3.6E-67 T 13-10-2018 THITH_14925 b63f360507b7d32472ad0ee14a8adcea 365 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 1 354 73.196 T 13-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 THITH_14925 b63f360507b7d32472ad0ee14a8adcea 365 SUPERFAMILY SSF56796 4 354 1.14E-119 T 13-10-2018 THITH_14925 b63f360507b7d32472ad0ee14a8adcea 365 Gene3D G3DSA:1.20.1090.10 171 356 6.4E-66 T 13-10-2018 THITH_14925 b63f360507b7d32472ad0ee14a8adcea 365 PIRSF PIRSF001455 6 352 9.6E-107 T 13-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 THITH_15115 f2016969c301048c432cc337c97ea5f3 318 Gene3D G3DSA:3.40.50.300 19 264 3.5E-37 T 13-10-2018 THITH_15115 f2016969c301048c432cc337c97ea5f3 318 SMART SM00382 45 221 2.4E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_15115 f2016969c301048c432cc337c97ea5f3 318 Gene3D G3DSA:1.10.10.60 266 308 1.9E-6 T 13-10-2018 THITH_15115 f2016969c301048c432cc337c97ea5f3 318 SUPERFAMILY SSF46689 270 313 7.7E-6 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_15115 f2016969c301048c432cc337c97ea5f3 318 Pfam PF13936 Helix-turn-helix domain 278 306 8.1E-7 T 13-10-2018 IPR025246 Transposase IS30-like HTH domain THITH_15115 f2016969c301048c432cc337c97ea5f3 318 Pfam PF13481 AAA domain 27 199 1.5E-26 T 13-10-2018 THITH_15115 f2016969c301048c432cc337c97ea5f3 318 SUPERFAMILY SSF52540 39 240 1.14E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_05995 8ece2305f646af8b55d2ca7f5608bbf6 95 Pfam PF01541 GIY-YIG catalytic domain 4 75 4.1E-14 T 13-10-2018 IPR000305 GIY-YIG endonuclease THITH_05995 8ece2305f646af8b55d2ca7f5608bbf6 95 SMART SM00465 3 81 2.8E-4 T 13-10-2018 IPR000305 GIY-YIG endonuclease THITH_05995 8ece2305f646af8b55d2ca7f5608bbf6 95 Gene3D G3DSA:3.40.1440.10 1 92 4.6E-18 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 THITH_05995 8ece2305f646af8b55d2ca7f5608bbf6 95 SUPERFAMILY SSF82771 3 90 5.75E-22 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 THITH_09660 ea6f7016809cfd775a05ab62737f40df 1212 Pfam PF01968 Hydantoinase/oxoprolinase 214 501 1.5E-109 T 13-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 THITH_09660 ea6f7016809cfd775a05ab62737f40df 1212 Pfam PF02538 Hydantoinase B/oxoprolinase 702 1209 4.4E-197 T 13-10-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 THITH_09660 ea6f7016809cfd775a05ab62737f40df 1212 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 16 194 2.7E-57 T 13-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 THITH_09310 acdc6f46ade674c274be6771bd04b1d7 125 Gene3D G3DSA:3.30.70.240 28 111 3.3E-17 T 13-10-2018 THITH_09310 acdc6f46ade674c274be6771bd04b1d7 125 Pfam PF09827 CRISPR associated protein Cas2 32 102 3.9E-15 T 13-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 THITH_09310 acdc6f46ade674c274be6771bd04b1d7 125 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 32 103 7.4E-12 T 13-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THITH_09310 acdc6f46ade674c274be6771bd04b1d7 125 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 30 109 13.371 T 13-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THITH_09310 acdc6f46ade674c274be6771bd04b1d7 125 SUPERFAMILY SSF143430 32 104 9.94E-17 T 13-10-2018 THITH_00700 abb262125980417cc0a1ea194781eb99 475 Pfam PF02321 Outer membrane efflux protein 242 425 5.0E-25 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 THITH_00700 abb262125980417cc0a1ea194781eb99 475 Pfam PF02321 Outer membrane efflux protein 33 218 2.0E-20 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 THITH_00700 abb262125980417cc0a1ea194781eb99 475 Gene3D G3DSA:1.20.1600.10 30 439 1.1E-77 T 13-10-2018 THITH_00700 abb262125980417cc0a1ea194781eb99 475 SUPERFAMILY SSF56954 32 445 6.93E-75 T 13-10-2018 THITH_00700 abb262125980417cc0a1ea194781eb99 475 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 30 435 8.2E-70 T 13-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 THITH_09950 d44fce6ea59623dfe2c7318e0c4e6767 520 Gene3D G3DSA:2.60.40.10 411 520 2.5E-19 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_09950 d44fce6ea59623dfe2c7318e0c4e6767 520 SUPERFAMILY SSF81296 409 518 1.96E-29 T 13-10-2018 IPR014756 Immunoglobulin E-set THITH_09950 d44fce6ea59623dfe2c7318e0c4e6767 520 Pfam PF04349 Periplasmic glucan biosynthesis protein, MdoG 34 515 3.7E-185 T 13-10-2018 IPR007444 Glucan biosynthesis, periplasmic, MdoG C-terminal GO:0016051|GO:0042597 THITH_09950 d44fce6ea59623dfe2c7318e0c4e6767 520 PIRSF PIRSF006281 8 519 3.3E-176 T 13-10-2018 IPR014438 Glucan biosynthesis protein MdoG/MdoD THITH_09950 d44fce6ea59623dfe2c7318e0c4e6767 520 SUPERFAMILY SSF74650 34 402 1.32E-137 T 13-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 THITH_09950 d44fce6ea59623dfe2c7318e0c4e6767 520 Gene3D G3DSA:2.70.98.10 33 405 6.4E-153 T 13-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 THITH_13480 589c51c5b601c4af5da56c0e0f422923 497 SUPERFAMILY SSF64153 7 247 1.7E-58 T 13-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 THITH_13480 589c51c5b601c4af5da56c0e0f422923 497 Gene3D G3DSA:3.40.1190.20 221 492 2.2E-76 T 13-10-2018 IPR029056 Ribokinase-like THITH_13480 589c51c5b601c4af5da56c0e0f422923 497 PIRSF PIRSF017184 6 493 5.7E-121 T 13-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 THITH_13480 589c51c5b601c4af5da56c0e0f422923 497 Pfam PF03853 YjeF-related protein N-terminus 30 189 1.5E-38 T 13-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 THITH_13480 589c51c5b601c4af5da56c0e0f422923 497 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 14 210 8.4E-45 T 13-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 THITH_13480 589c51c5b601c4af5da56c0e0f422923 497 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 9 210 23.749 T 13-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 THITH_13480 589c51c5b601c4af5da56c0e0f422923 497 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 225 497 21.714 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 THITH_13480 589c51c5b601c4af5da56c0e0f422923 497 Gene3D G3DSA:3.40.50.10260 3 217 1.0E-56 T 13-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 THITH_13480 589c51c5b601c4af5da56c0e0f422923 497 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 431 441 - T 13-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site THITH_13480 589c51c5b601c4af5da56c0e0f422923 497 SUPERFAMILY SSF53613 223 490 4.36E-64 T 13-10-2018 IPR029056 Ribokinase-like THITH_13480 589c51c5b601c4af5da56c0e0f422923 497 Pfam PF01256 Carbohydrate kinase 248 489 1.2E-51 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 THITH_13480 589c51c5b601c4af5da56c0e0f422923 497 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 227 490 1.1E-63 T 13-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 THITH_13480 589c51c5b601c4af5da56c0e0f422923 497 ProSitePatterns PS01049 YjeF C-terminal domain signature 1. 315 325 - T 13-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site THITH_03650 4e5090b60eea821ff8b2870a81c55384 513 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 3 509 44.086 T 13-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THITH_03650 4e5090b60eea821ff8b2870a81c55384 513 SUPERFAMILY SSF110921 392 499 7.32E-26 T 13-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THITH_03650 4e5090b60eea821ff8b2870a81c55384 513 Pfam PF00682 HMGL-like 6 274 5.5E-98 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 THITH_03650 4e5090b60eea821ff8b2870a81c55384 513 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 5 497 1.8E-222 T 13-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THITH_03650 4e5090b60eea821ff8b2870a81c55384 513 SMART SM00917 370 500 1.8E-41 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THITH_03650 4e5090b60eea821ff8b2870a81c55384 513 SUPERFAMILY SSF51569 3 292 2.01E-102 T 13-10-2018 THITH_03650 4e5090b60eea821ff8b2870a81c55384 513 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 13 29 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THITH_03650 4e5090b60eea821ff8b2870a81c55384 513 Gene3D G3DSA:3.30.160.270 395 500 1.3E-11 T 13-10-2018 THITH_03650 4e5090b60eea821ff8b2870a81c55384 513 Pfam PF08502 LeuA allosteric (dimerisation) domain 370 499 9.4E-37 T 13-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THITH_03650 4e5090b60eea821ff8b2870a81c55384 513 Gene3D G3DSA:1.10.238.260 281 394 2.8E-38 T 13-10-2018 THITH_03650 4e5090b60eea821ff8b2870a81c55384 513 Gene3D G3DSA:3.20.20.70 2 277 4.1E-111 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_03650 4e5090b60eea821ff8b2870a81c55384 513 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 200 213 - T 13-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 THITH_01270 47b16230a7e42cd457dbc0cb5e90b731 469 SMART SM01230 102 379 2.8E-144 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THITH_01270 47b16230a7e42cd457dbc0cb5e90b731 469 SUPERFAMILY SSF54368 3 100 5.49E-36 T 13-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THITH_01270 47b16230a7e42cd457dbc0cb5e90b731 469 Gene3D G3DSA:3.30.590.10 105 457 6.1E-145 T 13-10-2018 THITH_01270 47b16230a7e42cd457dbc0cb5e90b731 469 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 14 95 7.2E-31 T 13-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 THITH_01270 47b16230a7e42cd457dbc0cb5e90b731 469 SUPERFAMILY SSF55931 102 468 6.18E-136 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 THITH_01270 47b16230a7e42cd457dbc0cb5e90b731 469 Pfam PF00120 Glutamine synthetase, catalytic domain 103 466 3.2E-136 T 13-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THITH_01270 47b16230a7e42cd457dbc0cb5e90b731 469 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 5 468 4.7E-203 T 13-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THITH_01270 47b16230a7e42cd457dbc0cb5e90b731 469 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 386 398 - T 13-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THITH_01270 47b16230a7e42cd457dbc0cb5e90b731 469 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 259 274 - T 13-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 THITH_01270 47b16230a7e42cd457dbc0cb5e90b731 469 ProSitePatterns PS00180 Glutamine synthetase signature 1. 50 68 - T 13-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 THITH_01270 47b16230a7e42cd457dbc0cb5e90b731 469 Gene3D G3DSA:3.10.20.70 2 104 1.4E-38 T 13-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 THITH_05885 1992887d2e9e7e3d7e659222ee93cf31 143 SUPERFAMILY SSF88723 6 136 2.58E-15 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_05885 1992887d2e9e7e3d7e659222ee93cf31 143 Gene3D G3DSA:3.40.50.1010 5 131 1.4E-7 T 13-10-2018 THITH_05885 1992887d2e9e7e3d7e659222ee93cf31 143 Pfam PF01850 PIN domain 6 119 4.2E-8 T 13-10-2018 IPR002716 PIN domain THITH_10300 3fc94fdbfb46c43b73dcd6f7ce954bc7 263 SUPERFAMILY SSF53850 39 261 1.96E-33 T 13-10-2018 THITH_10300 3fc94fdbfb46c43b73dcd6f7ce954bc7 263 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 44 261 1.2E-20 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THITH_10300 3fc94fdbfb46c43b73dcd6f7ce954bc7 263 SMART SM00062 38 263 0.003 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THITH_10300 3fc94fdbfb46c43b73dcd6f7ce954bc7 263 Gene3D G3DSA:3.40.190.10 125 220 2.6E-25 T 13-10-2018 THITH_10300 3fc94fdbfb46c43b73dcd6f7ce954bc7 263 Gene3D G3DSA:3.40.190.10 44 258 2.6E-25 T 13-10-2018 THITH_01990 e5dada8b2f95bee462acb1d4e9c22be5 463 SUPERFAMILY SSF52467 287 461 5.12E-70 T 13-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily THITH_01990 e5dada8b2f95bee462acb1d4e9c22be5 463 Gene3D G3DSA:3.40.50.1220 278 462 7.7E-80 T 13-10-2018 THITH_01990 e5dada8b2f95bee462acb1d4e9c22be5 463 Pfam PF02233 NAD(P) transhydrogenase beta subunit 9 457 9.0E-174 T 13-10-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 THITH_01990 e5dada8b2f95bee462acb1d4e9c22be5 463 PIRSF PIRSF000204 3 461 7.0E-159 T 13-10-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 THITH_11450 c55ff72c4a6eb68923a4e32a7b243983 153 Pfam PF01878 EVE domain 3 148 5.4E-56 T 13-10-2018 IPR002740 EVE domain THITH_11450 c55ff72c4a6eb68923a4e32a7b243983 153 SUPERFAMILY SSF88697 1 150 3.56E-62 T 13-10-2018 IPR015947 PUA-like superfamily THITH_11450 c55ff72c4a6eb68923a4e32a7b243983 153 Gene3D G3DSA:3.10.590.10 1 153 1.9E-66 T 13-10-2018 THITH_17055 b6947f107d4bbd8f66e56fe3fd4252d5 286 Gene3D G3DSA:3.90.1070.10 101 177 1.4E-55 T 13-10-2018 THITH_17055 b6947f107d4bbd8f66e56fe3fd4252d5 286 SUPERFAMILY SSF56784 3 232 4.59E-22 T 13-10-2018 IPR036412 HAD-like superfamily THITH_17055 b6947f107d4bbd8f66e56fe3fd4252d5 286 Gene3D G3DSA:3.40.50.1000 6 269 1.4E-55 T 13-10-2018 IPR023214 HAD superfamily THITH_17055 b6947f107d4bbd8f66e56fe3fd4252d5 286 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 6 215 1.2E-13 T 13-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 THITH_17055 b6947f107d4bbd8f66e56fe3fd4252d5 286 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 4 270 2.4E-45 T 13-10-2018 IPR006380 Sucrose-phosphatase-like, N-terminal THITH_16945 c71525d6f0beedc5b3df953a0bc75258 683 Gene3D G3DSA:3.40.50.300 213 440 6.7E-80 T 13-10-2018 THITH_16945 c71525d6f0beedc5b3df953a0bc75258 683 Pfam PF17191 RecG wedge domain 10 165 3.7E-12 T 13-10-2018 IPR033454 RecG, wedge domain THITH_16945 c71525d6f0beedc5b3df953a0bc75258 683 SUPERFAMILY SSF50249 1 169 1.23E-31 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_16945 c71525d6f0beedc5b3df953a0bc75258 683 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 25 653 1.4E-204 T 13-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 THITH_16945 c71525d6f0beedc5b3df953a0bc75258 683 SUPERFAMILY SSF52540 442 644 3.74E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16945 c71525d6f0beedc5b3df953a0bc75258 683 Pfam PF00270 DEAD/DEAH box helicase 265 422 1.7E-13 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THITH_16945 c71525d6f0beedc5b3df953a0bc75258 683 SMART SM00490 495 579 6.2E-26 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_16945 c71525d6f0beedc5b3df953a0bc75258 683 SUPERFAMILY SSF52540 205 444 2.4E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16945 c71525d6f0beedc5b3df953a0bc75258 683 Pfam PF00271 Helicase conserved C-terminal domain 475 578 2.8E-18 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_16945 c71525d6f0beedc5b3df953a0bc75258 683 Gene3D G3DSA:3.40.50.300 448 620 3.9E-57 T 13-10-2018 THITH_16945 c71525d6f0beedc5b3df953a0bc75258 683 SMART SM00487 258 450 4.3E-29 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_07300 9e84d39cdfc621a996a5165f23280e05 447 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 151 426 1.7E-87 T 13-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 THITH_07300 9e84d39cdfc621a996a5165f23280e05 447 SUPERFAMILY SSF101960 22 436 1.7E-115 T 13-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily THITH_07300 9e84d39cdfc621a996a5165f23280e05 447 Pfam PF01458 Uncharacterized protein family (UPF0051) 186 410 3.2E-80 T 13-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 THITH_09960 7061d3dcd93a656210374462ec809ea2 286 Gene3D G3DSA:3.20.20.140 31 281 8.5E-27 T 13-10-2018 THITH_09960 7061d3dcd93a656210374462ec809ea2 286 Pfam PF04909 Amidohydrolase 43 278 5.2E-10 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 THITH_09960 7061d3dcd93a656210374462ec809ea2 286 SUPERFAMILY SSF51556 30 278 1.05E-17 T 13-10-2018 IPR032466 Metal-dependent hydrolase THITH_04935 7d67a9ca29438aa31fbc44ffb3fd3765 377 SUPERFAMILY SSF55729 177 352 8.25E-41 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_04935 7d67a9ca29438aa31fbc44ffb3fd3765 377 Gene3D G3DSA:3.40.630.30 174 319 1.3E-7 T 13-10-2018 THITH_04935 7d67a9ca29438aa31fbc44ffb3fd3765 377 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 7 374 1.7E-145 T 13-10-2018 IPR007434 Peptidogalycan biosysnthesis/recognition THITH_02680 09c21b6127e9678c8cb8d6f032b8406b 169 SUPERFAMILY SSF50447 7 94 2.93E-18 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THITH_02680 09c21b6127e9678c8cb8d6f032b8406b 169 Pfam PF01782 RimM N-terminal domain 10 90 1.5E-20 T 13-10-2018 IPR002676 RimM, N-terminal GO:0006364 THITH_02680 09c21b6127e9678c8cb8d6f032b8406b 169 Gene3D G3DSA:2.30.30.240 95 169 4.5E-24 T 13-10-2018 THITH_02680 09c21b6127e9678c8cb8d6f032b8406b 169 Gene3D G3DSA:2.40.30.60 2 94 8.2E-24 T 13-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 THITH_02680 09c21b6127e9678c8cb8d6f032b8406b 169 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 7 169 21.547 T 13-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 THITH_02680 09c21b6127e9678c8cb8d6f032b8406b 169 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 8 168 5.6E-42 T 13-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 THITH_02680 09c21b6127e9678c8cb8d6f032b8406b 169 Pfam PF05239 PRC-barrel domain 98 163 2.9E-5 T 13-10-2018 IPR027275 PRC-barrel domain THITH_02680 09c21b6127e9678c8cb8d6f032b8406b 169 SUPERFAMILY SSF50346 100 169 4.71E-17 T 13-10-2018 IPR011033 PRC-barrel-like superfamily THITH_14455 9e373a1541ab9cf22a8701d77b1a032a 302 Gene3D G3DSA:3.30.43.10 3 82 3.6E-22 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 THITH_14455 9e373a1541ab9cf22a8701d77b1a032a 302 SUPERFAMILY SSF56194 193 297 3.79E-36 T 13-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_14455 9e373a1541ab9cf22a8701d77b1a032a 302 Pfam PF01565 FAD binding domain 35 157 3.8E-19 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THITH_14455 9e373a1541ab9cf22a8701d77b1a032a 302 SUPERFAMILY SSF56176 2 191 6.54E-38 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 THITH_14455 9e373a1541ab9cf22a8701d77b1a032a 302 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 302 87.174 T 13-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_14455 9e373a1541ab9cf22a8701d77b1a032a 302 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 21 296 1.1E-57 T 13-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_14455 9e373a1541ab9cf22a8701d77b1a032a 302 Gene3D G3DSA:3.30.465.10 87 212 4.0E-31 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 THITH_14455 9e373a1541ab9cf22a8701d77b1a032a 302 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 198 294 4.7E-31 T 13-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_14455 9e373a1541ab9cf22a8701d77b1a032a 302 Gene3D G3DSA:3.90.78.10 213 302 3.2E-34 T 13-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_05495 9cbb9a8a8e53a9a113c12bc9c5557e48 174 SUPERFAMILY SSF49785 19 157 2.04E-10 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily THITH_06605 e4960f27cd8e0d0611ade549018ce3d3 250 Hamap MF_01523 Ribosomal RNA small subunit methyltransferase J [rsmJ]. 6 236 28.098 T 13-10-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 THITH_06605 e4960f27cd8e0d0611ade549018ce3d3 250 Gene3D G3DSA:3.40.50.150 45 241 8.2E-58 T 13-10-2018 THITH_06605 e4960f27cd8e0d0611ade549018ce3d3 250 Pfam PF04445 Putative SAM-dependent methyltransferase 17 234 6.5E-56 T 13-10-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 THITH_06605 e4960f27cd8e0d0611ade549018ce3d3 250 SUPERFAMILY SSF53335 23 234 8.79E-50 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_14830 08ec6ce7141d8d4609c551ee6971d0d5 876 Pfam PF01433 Peptidase family M1 domain 213 444 2.3E-57 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THITH_14830 08ec6ce7141d8d4609c551ee6971d0d5 876 Gene3D G3DSA:1.25.50.10 555 875 9.0E-94 T 13-10-2018 IPR037144 Peptidase M1, alanyl aminopeptidase, C-terminal domain superfamily THITH_14830 08ec6ce7141d8d4609c551ee6971d0d5 876 Gene3D G3DSA:2.60.40.1840 449 552 1.0E-23 T 13-10-2018 IPR038438 Alanyl aminopeptidase, Ig-like domain superfamily THITH_14830 08ec6ce7141d8d4609c551ee6971d0d5 876 TIGRFAM TIGR02414 pepN_proteo: aminopeptidase N 13 873 0.0 T 13-10-2018 IPR012779 Peptidase M1, alanyl aminopeptidase GO:0008270 THITH_14830 08ec6ce7141d8d4609c551ee6971d0d5 876 SUPERFAMILY SSF55486 209 454 9.08E-76 T 13-10-2018 THITH_14830 08ec6ce7141d8d4609c551ee6971d0d5 876 Gene3D G3DSA:2.60.40.1730 16 199 9.5E-68 T 13-10-2018 THITH_14830 08ec6ce7141d8d4609c551ee6971d0d5 876 Gene3D G3DSA:1.10.1740.60 200 284 1.8E-39 T 13-10-2018 THITH_14830 08ec6ce7141d8d4609c551ee6971d0d5 876 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 181 196 2.3E-8 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THITH_14830 08ec6ce7141d8d4609c551ee6971d0d5 876 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 263 273 2.3E-8 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THITH_14830 08ec6ce7141d8d4609c551ee6971d0d5 876 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 318 330 2.3E-8 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THITH_14830 08ec6ce7141d8d4609c551ee6971d0d5 876 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 299 314 2.3E-8 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THITH_14830 08ec6ce7141d8d4609c551ee6971d0d5 876 Pfam PF11940 Domain of unknown function (DUF3458) Ig-like fold 449 551 9.4E-22 T 13-10-2018 IPR035414 Peptidase M1, alanyl aminopeptidase, Ig-like fold THITH_14830 08ec6ce7141d8d4609c551ee6971d0d5 876 Gene3D G3DSA:1.10.390.10 285 448 8.7E-64 T 13-10-2018 IPR027268 Peptidase M4/M1, CTD superfamily THITH_14830 08ec6ce7141d8d4609c551ee6971d0d5 876 Pfam PF17432 Domain of unknown function (DUF3458_C) ARM repeats 557 874 1.8E-96 T 13-10-2018 IPR024601 Peptidase M1, alanyl aminopeptidase, C-terminal THITH_14830 08ec6ce7141d8d4609c551ee6971d0d5 876 SUPERFAMILY SSF63737 6 198 9.02E-39 T 13-10-2018 THITH_03430 6555c33f188d4569324fa4aa6cea3e67 1059 Pfam PF00271 Helicase conserved C-terminal domain 576 663 4.4E-8 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_03430 6555c33f188d4569324fa4aa6cea3e67 1059 SUPERFAMILY SSF52540 383 685 1.07E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_03430 6555c33f188d4569324fa4aa6cea3e67 1059 Gene3D G3DSA:3.30.870.10 133 295 1.5E-17 T 13-10-2018 THITH_03430 6555c33f188d4569324fa4aa6cea3e67 1059 Gene3D G3DSA:3.40.50.300 315 498 4.4E-39 T 13-10-2018 THITH_03430 6555c33f188d4569324fa4aa6cea3e67 1059 Pfam PF04851 Type III restriction enzyme, res subunit 328 483 2.5E-24 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THITH_03430 6555c33f188d4569324fa4aa6cea3e67 1059 Gene3D G3DSA:3.40.50.300 538 706 4.2E-28 T 13-10-2018 THITH_03430 6555c33f188d4569324fa4aa6cea3e67 1059 SUPERFAMILY SSF56024 214 290 8.79E-5 T 13-10-2018 THITH_03430 6555c33f188d4569324fa4aa6cea3e67 1059 Pfam PF11907 Domain of unknown function (DUF3427) 902 1052 8.9E-19 T 13-10-2018 IPR021835 Protein of unknown function DUF3427 THITH_03430 6555c33f188d4569324fa4aa6cea3e67 1059 SMART SM00487 325 510 1.9E-12 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_03430 6555c33f188d4569324fa4aa6cea3e67 1059 SMART SM00490 584 665 2.1E-8 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_06720 c50ce6f8a0c1e0fd039659184cd606f8 504 SUPERFAMILY SSF48208 183 444 8.16E-17 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 THITH_06720 c50ce6f8a0c1e0fd039659184cd606f8 504 Gene3D G3DSA:3.40.30.10 25 170 2.2E-20 T 13-10-2018 THITH_06720 c50ce6f8a0c1e0fd039659184cd606f8 504 SUPERFAMILY SSF52833 33 135 5.19E-23 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_06720 c50ce6f8a0c1e0fd039659184cd606f8 504 Pfam PF03190 Protein of unknown function, DUF255 30 101 2.0E-11 T 13-10-2018 IPR004879 Domain of unknown function DUF255 THITH_06720 c50ce6f8a0c1e0fd039659184cd606f8 504 Gene3D G3DSA:1.50.10.10 203 388 1.4E-15 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 THITH_08200 15dc4f248aaef60dc66e05340dcf1535 515 Pfam PF13247 4Fe-4S dicluster domain 175 271 8.5E-37 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_08200 15dc4f248aaef60dc66e05340dcf1535 515 SUPERFAMILY SSF54862 1 502 2.72E-179 T 13-10-2018 THITH_08200 15dc4f248aaef60dc66e05340dcf1535 515 Gene3D G3DSA:3.30.70.20 1 298 3.8E-101 T 13-10-2018 THITH_08200 15dc4f248aaef60dc66e05340dcf1535 515 Gene3D G3DSA:1.10.3650.10 358 434 2.2E-32 T 13-10-2018 IPR038262 Nitrate reductase beta, C-terminal domain superfamily KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 THITH_08200 15dc4f248aaef60dc66e05340dcf1535 515 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 492 1.3E-296 T 13-10-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 THITH_08200 15dc4f248aaef60dc66e05340dcf1535 515 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 358 435 3.5E-31 T 13-10-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 THITH_04515 955e8c212f6a363ae51a146e454b6907 242 SUPERFAMILY SSF52343 109 241 1.7E-31 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain THITH_04515 955e8c212f6a363ae51a146e454b6907 242 SUPERFAMILY SSF63380 11 110 3.03E-15 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel THITH_04515 955e8c212f6a363ae51a146e454b6907 242 Pfam PF00970 Oxidoreductase FAD-binding domain 17 109 1.5E-4 T 13-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 THITH_04515 955e8c212f6a363ae51a146e454b6907 242 Pfam PF00175 Oxidoreductase NAD-binding domain 121 222 3.0E-14 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THITH_04515 955e8c212f6a363ae51a146e454b6907 242 Gene3D G3DSA:3.40.50.80 114 242 8.2E-31 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain THITH_04515 955e8c212f6a363ae51a146e454b6907 242 Gene3D G3DSA:2.40.30.10 7 107 3.2E-14 T 13-10-2018 THITH_03220 3fa1e886dc2d9d439f44ad2b87ea1e0d 350 SUPERFAMILY SSF54197 194 290 9.69E-5 T 13-10-2018 IPR036265 HIT-like superfamily THITH_03220 3fa1e886dc2d9d439f44ad2b87ea1e0d 350 SUPERFAMILY SSF54197 69 182 5.53E-14 T 13-10-2018 IPR036265 HIT-like superfamily THITH_03220 3fa1e886dc2d9d439f44ad2b87ea1e0d 350 Gene3D G3DSA:3.30.428.10 96 184 3.4E-8 T 13-10-2018 IPR036265 HIT-like superfamily THITH_03220 3fa1e886dc2d9d439f44ad2b87ea1e0d 350 Gene3D G3DSA:3.30.428.10 187 318 1.5E-7 T 13-10-2018 IPR036265 HIT-like superfamily THITH_08165 442899f9aae6080c4e809dc684d00366 112 Pfam PF04358 DsrC like protein 7 107 8.3E-35 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_08165 442899f9aae6080c4e809dc684d00366 112 Gene3D G3DSA:1.10.10.370 40 108 2.1E-25 T 13-10-2018 THITH_08165 442899f9aae6080c4e809dc684d00366 112 Gene3D G3DSA:3.30.1420.10 5 38 4.7E-9 T 13-10-2018 THITH_08165 442899f9aae6080c4e809dc684d00366 112 PIRSF PIRSF006223 1 109 2.2E-32 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_08165 442899f9aae6080c4e809dc684d00366 112 SUPERFAMILY SSF69721 8 107 4.19E-31 T 13-10-2018 IPR025526 DsrC-like domain superfamily THITH_08165 442899f9aae6080c4e809dc684d00366 112 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 7 107 1.1E-30 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 631 649 - T 13-10-2018 IPR028299 ClpA/B, conserved site 2 THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 294 306 - T 13-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 Gene3D G3DSA:1.10.1780.10 1 147 5.9E-39 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 145 1.1E-15 T 13-10-2018 IPR004176 Clp, N-terminal THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 69 6.8E-16 T 13-10-2018 IPR004176 Clp, N-terminal THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 Pfam PF07724 AAA domain (Cdc48 subfamily) 596 759 1.3E-55 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 Gene3D G3DSA:3.40.50.300 550 764 3.6E-88 T 13-10-2018 THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 203 335 7.0E-13 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 Gene3D G3DSA:1.10.8.60 766 857 1.0E-29 T 13-10-2018 THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 601 619 1.9E-42 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 708 722 1.9E-42 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 675 693 1.9E-42 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 646 664 1.9E-42 T 13-10-2018 IPR001270 ClpA/B family GO:0005524 THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 SMART SM00382 198 343 4.4E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 SMART SM00382 597 768 1.1E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 Gene3D G3DSA:3.40.50.300 343 544 1.6E-70 T 13-10-2018 THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 Gene3D G3DSA:3.40.50.300 148 342 3.5E-74 T 13-10-2018 THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 855 0.0 T 13-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 SUPERFAMILY SSF52540 546 855 5.14E-81 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 SUPERFAMILY SSF81923 4 156 3.83E-44 T 13-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 SMART SM01086 766 855 9.6E-41 T 13-10-2018 IPR019489 Clp ATPase, C-terminal THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 766 846 7.5E-27 T 13-10-2018 IPR019489 Clp ATPase, C-terminal THITH_13970 a2579e6ff8183ff85c18b032a3e33f51 857 SUPERFAMILY SSF52540 158 545 2.41E-101 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_17310 0f482016e557de14968d2245b847233d 335 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 229 245 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site THITH_17310 0f482016e557de14968d2245b847233d 335 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 153 180 - T 13-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 THITH_17310 0f482016e557de14968d2245b847233d 335 Gene3D G3DSA:3.40.50.720 11 323 6.5E-134 T 13-10-2018 THITH_17310 0f482016e557de14968d2245b847233d 335 Gene3D G3DSA:3.40.50.720 108 303 6.5E-134 T 13-10-2018 THITH_17310 0f482016e557de14968d2245b847233d 335 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 117 303 1.6E-55 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 THITH_17310 0f482016e557de14968d2245b847233d 335 SUPERFAMILY SSF51735 108 304 8.58E-58 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_17310 0f482016e557de14968d2245b847233d 335 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 15 333 7.7E-29 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 THITH_17310 0f482016e557de14968d2245b847233d 335 SUPERFAMILY SSF52283 8 140 1.34E-37 T 13-10-2018 THITH_17310 0f482016e557de14968d2245b847233d 335 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 200 222 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site THITH_11575 4511282c06f54f8045cc606dd76efb3b 412 Pfam PF06245 Protein of unknown function (DUF1015) 4 409 1.2E-135 T 13-10-2018 IPR008323 Uncharacterised conserved protein UCP033563 THITH_11575 4511282c06f54f8045cc606dd76efb3b 412 PIRSF PIRSF033563 1 412 6.6E-135 T 13-10-2018 IPR008323 Uncharacterised conserved protein UCP033563 THITH_00380 3d97e561d60081a611942e730c20d307 188 Gene3D G3DSA:3.90.1570.10 4 185 1.6E-21 T 13-10-2018 THITH_00380 3d97e561d60081a611942e730c20d307 188 Pfam PF05685 Putative restriction endonuclease 13 166 5.7E-29 T 13-10-2018 IPR008538 Domain of unknown function DUF820 THITH_00380 3d97e561d60081a611942e730c20d307 188 SUPERFAMILY SSF52980 7 164 5.36E-26 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 Pfam PF04983 RNA polymerase Rpb1, domain 3 489 641 6.5E-28 T 13-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 Gene3D G3DSA:1.10.132.30 638 787 8.6E-66 T 13-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 10 1369 19.052 T 13-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 SMART SM00663 235 514 2.5E-181 T 13-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 Gene3D G3DSA:1.10.150.390 1311 1371 7.2E-27 T 13-10-2018 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 Gene3D G3DSA:1.10.274.100 490 562 5.1E-25 T 13-10-2018 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 Gene3D G3DSA:1.10.1790.20 1132 1309 1.7E-62 T 13-10-2018 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 Pfam PF00623 RNA polymerase Rpb1, domain 2 344 395 9.9E-8 T 13-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 Pfam PF00623 RNA polymerase Rpb1, domain 2 389 485 2.9E-27 T 13-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 Pfam PF05000 RNA polymerase Rpb1, domain 4 671 760 1.6E-18 T 13-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 Pfam PF04998 RNA polymerase Rpb1, domain 5 763 1309 5.1E-76 T 13-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 Gene3D G3DSA:1.10.274.100 563 637 1.3E-14 T 13-10-2018 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 Gene3D G3DSA:2.40.50.100 945 1019 3.3E-28 T 13-10-2018 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 SUPERFAMILY SSF64484 15 1358 0.0 T 13-10-2018 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 19 1033 0.0 T 13-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 Gene3D G3DSA:2.40.50.100 1020 1123 3.9E-30 T 13-10-2018 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 Gene3D G3DSA:1.10.40.90 374 416 3.9E-21 T 13-10-2018 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 Pfam PF04997 RNA polymerase Rpb1, domain 1 15 342 1.1E-88 T 13-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 THITH_14320 64661381ae1f0d65ce840f6aec4556da 1402 Gene3D G3DSA:2.40.50.100 1148 1211 1.7E-62 T 13-10-2018 THITH_15880 02ddb69b48663fdc692b392d6d29c4a0 227 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 9 222 1.7E-67 T 13-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 THITH_15880 02ddb69b48663fdc692b392d6d29c4a0 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 83 193 1.1E-12 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_15880 02ddb69b48663fdc692b392d6d29c4a0 227 Gene3D G3DSA:3.40.50.1000 9 214 1.9E-61 T 13-10-2018 IPR023214 HAD superfamily THITH_15880 02ddb69b48663fdc692b392d6d29c4a0 227 SUPERFAMILY SSF56784 4 222 3.44E-57 T 13-10-2018 IPR036412 HAD-like superfamily THITH_15880 02ddb69b48663fdc692b392d6d29c4a0 227 Hamap MF_00495 Phosphoglycolate phosphatase [gph]. 6 223 38.982 T 13-10-2018 IPR037512 Phosphoglycolate phosphatase, prokaryotic GO:0005975|GO:0008967 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 THITH_15880 02ddb69b48663fdc692b392d6d29c4a0 227 Gene3D G3DSA:1.10.150.240 21 92 1.9E-61 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 THITH_15880 02ddb69b48663fdc692b392d6d29c4a0 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 191 8.5E-33 T 13-10-2018 THITH_15880 02ddb69b48663fdc692b392d6d29c4a0 227 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 107 187 2.1E-9 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_15880 02ddb69b48663fdc692b392d6d29c4a0 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 137 153 1.3E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_15880 02ddb69b48663fdc692b392d6d29c4a0 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 6 17 1.3E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_15880 02ddb69b48663fdc692b392d6d29c4a0 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 106 119 1.3E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_15880 02ddb69b48663fdc692b392d6d29c4a0 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 182 195 1.3E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_07470 8abadeea6249801df64b498d523e83b8 213 Pfam PF01625 Peptide methionine sulfoxide reductase 43 191 1.9E-58 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 THITH_07470 8abadeea6249801df64b498d523e83b8 213 SUPERFAMILY SSF55068 13 202 4.97E-75 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 THITH_07470 8abadeea6249801df64b498d523e83b8 213 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 40 197 35.257 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 THITH_07470 8abadeea6249801df64b498d523e83b8 213 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 43 190 2.8E-57 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 THITH_07470 8abadeea6249801df64b498d523e83b8 213 Gene3D G3DSA:3.30.1060.10 26 202 5.3E-67 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 THITH_07655 f876d300b5a46f30ebb04179358e0e12 205 Hamap MF_00528 Septum formation protein Maf [maf]. 6 194 28.647 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 THITH_07655 f876d300b5a46f30ebb04179358e0e12 205 Pfam PF02545 Maf-like protein 7 189 7.3E-43 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 THITH_07655 f876d300b5a46f30ebb04179358e0e12 205 TIGRFAM TIGR00172 maf: septum formation protein Maf 6 188 2.9E-50 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 THITH_07655 f876d300b5a46f30ebb04179358e0e12 205 SUPERFAMILY SSF52972 5 189 4.45E-55 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like THITH_07655 f876d300b5a46f30ebb04179358e0e12 205 PIRSF PIRSF006305 1 195 3.3E-42 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 THITH_07655 f876d300b5a46f30ebb04179358e0e12 205 Gene3D G3DSA:3.90.950.10 6 194 3.5E-57 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like THITH_03050 f341aec8297b3bb9909c3f30e45d61ad 356 Pfam PF03459 TOBE domain 293 355 1.1E-9 T 13-10-2018 IPR005116 Transport-associated OB, type 1 THITH_03050 f341aec8297b3bb9909c3f30e45d61ad 356 SMART SM00382 24 209 6.0E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_03050 f341aec8297b3bb9909c3f30e45d61ad 356 SUPERFAMILY SSF50331 237 354 2.11E-13 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal THITH_03050 f341aec8297b3bb9909c3f30e45d61ad 356 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_03050 f341aec8297b3bb9909c3f30e45d61ad 356 TIGRFAM TIGR02142 modC_ABC: molybdate ABC transporter, ATP-binding protein 9 354 7.7E-110 T 13-10-2018 IPR011868 Molybdate ABC transporter, ATP-binding protein GO:0005524|GO:0015098|GO:0015689|GO:0016020 THITH_03050 f341aec8297b3bb9909c3f30e45d61ad 356 Gene3D G3DSA:2.40.50.100 291 355 2.6E-12 T 13-10-2018 THITH_03050 f341aec8297b3bb9909c3f30e45d61ad 356 SUPERFAMILY SSF52540 12 230 2.97E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_03050 f341aec8297b3bb9909c3f30e45d61ad 356 Pfam PF00005 ABC transporter 17 160 4.7E-26 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_03050 f341aec8297b3bb9909c3f30e45d61ad 356 Gene3D G3DSA:3.40.50.300 15 241 3.8E-58 T 13-10-2018 THITH_15340 cbe2daacdd55f53a75b35a940b770783 347 SUPERFAMILY SSF51395 18 296 4.03E-79 T 13-10-2018 THITH_15340 cbe2daacdd55f53a75b35a940b770783 347 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 19 317 1.4E-105 T 13-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 THITH_15340 cbe2daacdd55f53a75b35a940b770783 347 Pfam PF01207 Dihydrouridine synthase (Dus) 21 310 8.4E-99 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 THITH_15340 cbe2daacdd55f53a75b35a940b770783 347 PIRSF PIRSF006621 8 335 1.4E-97 T 13-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 THITH_15340 cbe2daacdd55f53a75b35a940b770783 347 Gene3D G3DSA:3.20.20.70 17 254 1.8E-75 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_15340 cbe2daacdd55f53a75b35a940b770783 347 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 101 119 - T 13-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 THITH_01970 1ba4d83b37e32622f21dfd9dfd0a1677 1317 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 629 704 6.2E-18 T 13-10-2018 IPR011709 Domain of unknown function DUF1605 THITH_01970 1ba4d83b37e32622f21dfd9dfd0a1677 1317 Gene3D G3DSA:1.20.120.1080 461 561 8.4E-17 T 13-10-2018 THITH_01970 1ba4d83b37e32622f21dfd9dfd0a1677 1317 SMART SM00382 94 382 6.8E-4 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_01970 1ba4d83b37e32622f21dfd9dfd0a1677 1317 SMART SM00847 476 566 1.6E-31 T 13-10-2018 IPR007502 Helicase-associated domain GO:0004386 THITH_01970 1ba4d83b37e32622f21dfd9dfd0a1677 1317 Gene3D G3DSA:3.40.50.300 255 432 7.6E-52 T 13-10-2018 THITH_01970 1ba4d83b37e32622f21dfd9dfd0a1677 1317 Pfam PF11898 Domain of unknown function (DUF3418) 719 1298 3.2E-189 T 13-10-2018 IPR024590 RNA helicase HrpA, C-terminal THITH_01970 1ba4d83b37e32622f21dfd9dfd0a1677 1317 Gene3D G3DSA:3.40.50.300 42 254 6.4E-78 T 13-10-2018 THITH_01970 1ba4d83b37e32622f21dfd9dfd0a1677 1317 SMART SM00487 77 261 7.6E-29 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_01970 1ba4d83b37e32622f21dfd9dfd0a1677 1317 Pfam PF04408 Helicase associated domain (HA2) 479 564 3.0E-17 T 13-10-2018 IPR007502 Helicase-associated domain GO:0004386 THITH_01970 1ba4d83b37e32622f21dfd9dfd0a1677 1317 Pfam PF00271 Helicase conserved C-terminal domain 298 416 1.3E-10 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_01970 1ba4d83b37e32622f21dfd9dfd0a1677 1317 SUPERFAMILY SSF52540 79 596 3.58E-93 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01970 1ba4d83b37e32622f21dfd9dfd0a1677 1317 SMART SM00490 316 416 7.2E-13 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_01970 1ba4d83b37e32622f21dfd9dfd0a1677 1317 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 17 1297 0.0 T 13-10-2018 IPR010222 RNA helicase HrpA GO:0004004 THITH_15830 d1cffe95798094371b35cd392fb16e33 213 Hamap MF_01658 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase [coq7]. 11 213 26.764 T 13-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 THITH_15830 d1cffe95798094371b35cd392fb16e33 213 SUPERFAMILY SSF47240 53 182 2.78E-13 T 13-10-2018 IPR009078 Ferritin-like superfamily THITH_15830 d1cffe95798094371b35cd392fb16e33 213 Pfam PF03232 Ubiquinone biosynthesis protein COQ7 51 213 1.1E-40 T 13-10-2018 IPR011566 Ubiquinone biosynthesis protein Coq7 GO:0006744|GO:0055114 Reactome: R-HSA-2142789 THITH_06750 0b0562329566054127d8ef442839e59e 579 SUPERFAMILY SSF56762 4 564 6.8E-169 T 13-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_06750 0b0562329566054127d8ef442839e59e 579 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 555 564 - T 13-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THITH_06750 0b0562329566054127d8ef442839e59e 579 Gene3D G3DSA:1.10.645.10 2 564 4.1E-251 T 13-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_06750 0b0562329566054127d8ef442839e59e 579 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 41 66 - T 13-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THITH_06750 0b0562329566054127d8ef442839e59e 579 Pfam PF00374 Nickel-dependent hydrogenase 41 564 2.2E-223 T 13-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 THITH_09495 8aa36cbd6350594bfd36c63627b1209d 315 Gene3D G3DSA:3.40.718.10 1 300 3.2E-71 T 13-10-2018 THITH_09495 8aa36cbd6350594bfd36c63627b1209d 315 SMART SM01329 1 296 3.1E-37 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 THITH_09495 8aa36cbd6350594bfd36c63627b1209d 315 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 37 296 1.8E-59 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 THITH_09495 8aa36cbd6350594bfd36c63627b1209d 315 SUPERFAMILY SSF53659 34 300 1.77E-60 T 13-10-2018 THITH_14535 0466252e87b6f02b1b905b5b1a97c300 461 Gene3D G3DSA:3.30.43.10 2 90 7.5E-16 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 THITH_14535 0466252e87b6f02b1b905b5b1a97c300 461 Gene3D G3DSA:3.30.70.2190 214 329 6.4E-5 T 13-10-2018 THITH_14535 0466252e87b6f02b1b905b5b1a97c300 461 Gene3D G3DSA:3.30.70.2740 332 414 7.5E-17 T 13-10-2018 THITH_14535 0466252e87b6f02b1b905b5b1a97c300 461 SUPERFAMILY SSF56176 4 214 9.81E-62 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 THITH_14535 0466252e87b6f02b1b905b5b1a97c300 461 Gene3D G3DSA:1.10.45.10 415 455 1.7E-13 T 13-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 THITH_14535 0466252e87b6f02b1b905b5b1a97c300 461 Pfam PF02913 FAD linked oxidases, C-terminal domain 214 453 2.7E-65 T 13-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 THITH_14535 0466252e87b6f02b1b905b5b1a97c300 461 Pfam PF01565 FAD binding domain 38 176 6.1E-33 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THITH_14535 0466252e87b6f02b1b905b5b1a97c300 461 SUPERFAMILY SSF55103 218 458 5.23E-67 T 13-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 THITH_14535 0466252e87b6f02b1b905b5b1a97c300 461 Gene3D G3DSA:3.30.465.10 92 212 6.3E-39 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 THITH_14805 9047117ed2d883107bc3c72d0e95bda8 427 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 170 304 1.0E-44 T 13-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase THITH_14805 9047117ed2d883107bc3c72d0e95bda8 427 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 1 416 30.815 T 13-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THITH_14805 9047117ed2d883107bc3c72d0e95bda8 427 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 97 120 - T 13-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THITH_14805 9047117ed2d883107bc3c72d0e95bda8 427 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 5 154 1.1E-48 T 13-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THITH_14805 9047117ed2d883107bc3c72d0e95bda8 427 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 318 414 8.3E-25 T 13-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THITH_14805 9047117ed2d883107bc3c72d0e95bda8 427 Gene3D G3DSA:3.30.460.30 1 156 5.2E-56 T 13-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THITH_14805 9047117ed2d883107bc3c72d0e95bda8 427 SUPERFAMILY SSF69075 315 414 1.57E-26 T 13-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THITH_14805 9047117ed2d883107bc3c72d0e95bda8 427 SUPERFAMILY SSF51735 160 313 4.73E-35 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_14805 9047117ed2d883107bc3c72d0e95bda8 427 PIRSF PIRSF000445 1 424 1.5E-155 T 13-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THITH_14805 9047117ed2d883107bc3c72d0e95bda8 427 SUPERFAMILY SSF69742 2 156 4.05E-47 T 13-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THITH_14805 9047117ed2d883107bc3c72d0e95bda8 427 Gene3D G3DSA:3.40.50.720 159 311 1.5E-43 T 13-10-2018 THITH_14805 9047117ed2d883107bc3c72d0e95bda8 427 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 411 4.3E-141 T 13-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 THITH_11720 8394190a3ba80c534a73a04b50b2e710 466 SUPERFAMILY SSF53383 67 445 4.19E-46 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_11720 8394190a3ba80c534a73a04b50b2e710 466 TIGRFAM TIGR00474 selA: L-seryl-tRNA(Sec) selenium transferase 8 451 6.6E-176 T 13-10-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 THITH_11720 8394190a3ba80c534a73a04b50b2e710 466 Hamap MF_00423 L-seryl-tRNA(Sec) selenium transferase [selA]. 1 464 236.171 T 13-10-2018 IPR004534 L-seryl-tRNA(Sec) selenium transferase GO:0001514|GO:0004125|GO:0005737 KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 THITH_11720 8394190a3ba80c534a73a04b50b2e710 466 Pfam PF03841 L-seryl-tRNA selenium transferase 77 448 1.7E-165 T 13-10-2018 IPR018319 L-seryl-tRNA selenium transferase-like KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 THITH_11720 8394190a3ba80c534a73a04b50b2e710 466 Gene3D G3DSA:3.90.1150.110 8 449 1.4E-153 T 13-10-2018 THITH_11720 8394190a3ba80c534a73a04b50b2e710 466 Gene3D G3DSA:3.40.640.10 89 353 1.4E-153 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_11720 8394190a3ba80c534a73a04b50b2e710 466 Pfam PF12390 Selenocysteine synthase N terminal 8 43 1.1E-8 T 13-10-2018 IPR025862 L-seryl-tRNA selenium transferase N-terminal domain KEGG: 00450+2.9.1.1|KEGG: 00970+2.9.1.1 THITH_11290 55b71121b7904740da2e0865caadc1ea 883 Pfam PF00501 AMP-binding enzyme 17 440 4.6E-94 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 THITH_11290 55b71121b7904740da2e0865caadc1ea 883 SUPERFAMILY SSF56801 16 543 2.35E-119 T 13-10-2018 THITH_11290 55b71121b7904740da2e0865caadc1ea 883 Gene3D G3DSA:1.10.1200.10 582 651 9.2E-11 T 13-10-2018 IPR036736 ACP-like superfamily THITH_11290 55b71121b7904740da2e0865caadc1ea 883 Pfam PF00550 Phosphopantetheine attachment site 589 639 2.3E-6 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain THITH_11290 55b71121b7904740da2e0865caadc1ea 883 SUPERFAMILY SSF47336 587 643 4.97E-9 T 13-10-2018 IPR036736 ACP-like superfamily THITH_11290 55b71121b7904740da2e0865caadc1ea 883 ProSitePatterns PS00455 Putative AMP-binding domain signature. 161 172 - T 13-10-2018 IPR020845 AMP-binding, conserved site THITH_11290 55b71121b7904740da2e0865caadc1ea 883 SMART SM00563 713 830 1.7E-15 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 THITH_11290 55b71121b7904740da2e0865caadc1ea 883 SUPERFAMILY SSF69593 696 874 5.1E-27 T 13-10-2018 THITH_11290 55b71121b7904740da2e0865caadc1ea 883 Gene3D G3DSA:3.30.300.30 438 556 1.8E-14 T 13-10-2018 THITH_11290 55b71121b7904740da2e0865caadc1ea 883 Pfam PF01553 Acyltransferase 701 827 1.3E-11 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 THITH_11290 55b71121b7904740da2e0865caadc1ea 883 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 530 2.5E-7 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain THITH_12070 7b57e7ae607b7e8a84ee889831ed1eed 64 Gene3D G3DSA:2.20.25.10 8 64 9.3E-26 T 13-10-2018 THITH_12070 7b57e7ae607b7e8a84ee889831ed1eed 64 SUPERFAMILY SSF158997 1 55 5.49E-21 T 13-10-2018 THITH_12070 7b57e7ae607b7e8a84ee889831ed1eed 64 Hamap MF_01187 UPF0434 protein YcaR [ycaR]. 1 54 28.285 T 13-10-2018 IPR038053 Uncharacterised protein family UPF0434 THITH_12070 7b57e7ae607b7e8a84ee889831ed1eed 64 Pfam PF03966 Trm112p-like protein 2 40 5.4E-10 T 13-10-2018 IPR005651 Trm112-like THITH_03515 699cdc63f9d15f18c588da11cda4aa9a 392 PIRSF PIRSF001549 6 365 2.0E-43 T 13-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 THITH_03515 699cdc63f9d15f18c588da11cda4aa9a 392 SUPERFAMILY SSF55681 7 324 1.04E-55 T 13-10-2018 THITH_03515 699cdc63f9d15f18c588da11cda4aa9a 392 Gene3D G3DSA:3.30.930.10 5 334 2.1E-68 T 13-10-2018 THITH_03515 699cdc63f9d15f18c588da11cda4aa9a 392 Pfam PF13393 Histidyl-tRNA synthetase 12 323 1.8E-117 T 13-10-2018 THITH_03515 699cdc63f9d15f18c588da11cda4aa9a 392 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 15 327 2.1E-86 T 13-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 THITH_03515 699cdc63f9d15f18c588da11cda4aa9a 392 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 19 376 31.944 T 13-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 THITH_14875 d648980b31e4c4b1ac61fd5336893445 745 Pfam PF11741 AMIN domain 71 156 1.7E-7 T 13-10-2018 IPR021731 AMIN domain THITH_14875 d648980b31e4c4b1ac61fd5336893445 745 SMART SM00965 347 395 4.8E-10 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 THITH_14875 d648980b31e4c4b1ac61fd5336893445 745 Gene3D G3DSA:2.60.40.3500 56 157 3.5E-7 T 13-10-2018 THITH_14875 d648980b31e4c4b1ac61fd5336893445 745 TIGRFAM TIGR02515 IV_pilus_PilQ: type IV pilus secretin PilQ 322 744 2.4E-147 T 13-10-2018 IPR013355 Type IV pilus secretin PilQ THITH_14875 d648980b31e4c4b1ac61fd5336893445 745 Gene3D G3DSA:3.55.50.30 305 419 4.9E-42 T 13-10-2018 THITH_14875 d648980b31e4c4b1ac61fd5336893445 745 Pfam PF03958 Bacterial type II/III secretion system short domain 447 492 2.3E-10 T 13-10-2018 IPR005644 NolW-like THITH_14875 d648980b31e4c4b1ac61fd5336893445 745 Gene3D G3DSA:2.60.40.3470 182 304 2.7E-27 T 13-10-2018 THITH_14875 d648980b31e4c4b1ac61fd5336893445 745 Pfam PF07660 Secretin and TonB N terminus short domain 347 392 1.7E-8 T 13-10-2018 IPR011662 Secretin/TonB, short N-terminal domain GO:0019867 THITH_14875 d648980b31e4c4b1ac61fd5336893445 745 Gene3D G3DSA:3.30.1370.120 420 491 2.0E-9 T 13-10-2018 IPR038591 NolW-like superfamily THITH_14875 d648980b31e4c4b1ac61fd5336893445 745 Pfam PF00263 Bacterial type II and III secretion system protein 590 744 1.7E-38 T 13-10-2018 IPR004846 Type II/III secretion system GO:0009306 THITH_14875 d648980b31e4c4b1ac61fd5336893445 745 PRINTS PR00811 Bacterial general secretion pathway protein D signature 621 631 2.7E-13 T 13-10-2018 IPR001775 GspD/PilQ family THITH_14875 d648980b31e4c4b1ac61fd5336893445 745 PRINTS PR00811 Bacterial general secretion pathway protein D signature 732 745 2.7E-13 T 13-10-2018 IPR001775 GspD/PilQ family THITH_14875 d648980b31e4c4b1ac61fd5336893445 745 PRINTS PR00811 Bacterial general secretion pathway protein D signature 586 610 2.7E-13 T 13-10-2018 IPR001775 GspD/PilQ family THITH_14875 d648980b31e4c4b1ac61fd5336893445 745 PRINTS PR00811 Bacterial general secretion pathway protein D signature 492 502 2.7E-13 T 13-10-2018 IPR001775 GspD/PilQ family THITH_14875 d648980b31e4c4b1ac61fd5336893445 745 PRINTS PR00811 Bacterial general secretion pathway protein D signature 709 727 2.7E-13 T 13-10-2018 IPR001775 GspD/PilQ family THITH_06480 85d4dfb799e931b7e56dceaa29ce9d09 432 Gene3D G3DSA:1.10.645.10 5 423 6.6E-112 T 13-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_06480 85d4dfb799e931b7e56dceaa29ce9d09 432 SUPERFAMILY SSF56762 6 423 4.58E-95 T 13-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_06480 85d4dfb799e931b7e56dceaa29ce9d09 432 Pfam PF00374 Nickel-dependent hydrogenase 289 423 6.4E-10 T 13-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 THITH_06480 85d4dfb799e931b7e56dceaa29ce9d09 432 Pfam PF00374 Nickel-dependent hydrogenase 44 130 2.1E-13 T 13-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 THITH_06480 85d4dfb799e931b7e56dceaa29ce9d09 432 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 414 423 - T 13-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 THITH_16400 b3756d37c4f4249c5087c6f2e529fde1 367 SUPERFAMILY SSF58113 45 195 6.93E-5 T 13-10-2018 THITH_16400 b3756d37c4f4249c5087c6f2e529fde1 367 Gene3D G3DSA:1.20.120.20 35 197 5.2E-5 T 13-10-2018 THITH_16400 b3756d37c4f4249c5087c6f2e529fde1 367 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 44 287 2.0E-5 T 13-10-2018 THITH_10885 896f5c68632b82ee20358266ab4eddea 373 Pfam PF00005 ABC transporter 23 161 3.7E-29 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_10885 896f5c68632b82ee20358266ab4eddea 373 SUPERFAMILY SSF50331 236 369 1.21E-18 T 13-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal THITH_10885 896f5c68632b82ee20358266ab4eddea 373 Gene3D G3DSA:2.40.50.940 222 363 2.6E-20 T 13-10-2018 THITH_10885 896f5c68632b82ee20358266ab4eddea 373 SMART SM00382 28 219 3.2E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_10885 896f5c68632b82ee20358266ab4eddea 373 SUPERFAMILY SSF52540 4 242 9.0E-83 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_10885 896f5c68632b82ee20358266ab4eddea 373 Gene3D G3DSA:2.40.50.140 282 354 2.6E-20 T 13-10-2018 THITH_10885 896f5c68632b82ee20358266ab4eddea 373 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_10885 896f5c68632b82ee20358266ab4eddea 373 Gene3D G3DSA:3.40.50.300 3 221 1.5E-63 T 13-10-2018 THITH_10885 896f5c68632b82ee20358266ab4eddea 373 Pfam PF08402 TOBE domain 276 362 4.4E-6 T 13-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 THITH_05110 06f108c7c54af2f21d439aabfacb4b46 177 Pfam PF03477 ATP cone domain 51 134 5.4E-11 T 13-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 THITH_05110 06f108c7c54af2f21d439aabfacb4b46 177 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 148 4.3E-55 T 13-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 THITH_05110 06f108c7c54af2f21d439aabfacb4b46 177 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 155 75.993 T 13-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 THITH_10785 a5fe40a75afbd51dfb7b7255dcb7ad7c 341 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 8 120 4.0E-31 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THITH_10785 a5fe40a75afbd51dfb7b7255dcb7ad7c 341 Gene3D G3DSA:3.40.50.720 8 335 7.6E-147 T 13-10-2018 THITH_10785 a5fe40a75afbd51dfb7b7255dcb7ad7c 341 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 8 338 9.2E-134 T 13-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 THITH_10785 a5fe40a75afbd51dfb7b7255dcb7ad7c 341 SUPERFAMILY SSF51735 6 160 7.39E-49 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_10785 a5fe40a75afbd51dfb7b7255dcb7ad7c 341 SUPERFAMILY SSF55347 132 324 6.55E-77 T 13-10-2018 THITH_10785 a5fe40a75afbd51dfb7b7255dcb7ad7c 341 Gene3D G3DSA:3.30.360.10 131 320 7.6E-147 T 13-10-2018 THITH_10785 a5fe40a75afbd51dfb7b7255dcb7ad7c 341 PIRSF PIRSF000148 5 341 1.5E-132 T 13-10-2018 THITH_10785 a5fe40a75afbd51dfb7b7255dcb7ad7c 341 SMART SM00859 7 122 1.9E-42 T 13-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 THITH_10785 a5fe40a75afbd51dfb7b7255dcb7ad7c 341 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 142 323 6.1E-60 T 13-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 THITH_10785 a5fe40a75afbd51dfb7b7255dcb7ad7c 341 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 5 337 36.899 T 13-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 THITH_12205 fa99445b26b91517eb511297a5410e5d 295 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 30 278 7.3E-54 T 13-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 THITH_12205 fa99445b26b91517eb511297a5410e5d 295 Gene3D G3DSA:2.40.50.140 1 48 2.8E-7 T 13-10-2018 THITH_12205 fa99445b26b91517eb511297a5410e5d 295 Gene3D G3DSA:3.40.50.300 51 219 2.9E-36 T 13-10-2018 THITH_12205 fa99445b26b91517eb511297a5410e5d 295 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 4 285 26.981 T 13-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 THITH_12205 fa99445b26b91517eb511297a5410e5d 295 Pfam PF03193 RsgA GTPase 50 218 2.5E-37 T 13-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 THITH_12205 fa99445b26b91517eb511297a5410e5d 295 SUPERFAMILY SSF52540 63 281 1.17E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_12205 fa99445b26b91517eb511297a5410e5d 295 Gene3D G3DSA:1.10.40.50 223 289 6.4E-21 T 13-10-2018 THITH_16530 6c4cf1cc4c1f1424550e81b2551d1895 287 Gene3D G3DSA:3.40.50.150 13 206 9.7E-36 T 13-10-2018 THITH_16530 6c4cf1cc4c1f1424550e81b2551d1895 287 SUPERFAMILY SSF53335 12 245 9.94E-40 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_16530 6c4cf1cc4c1f1424550e81b2551d1895 287 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 7 268 32.086 T 13-10-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 THITH_16530 6c4cf1cc4c1f1424550e81b2551d1895 287 Pfam PF08241 Methyltransferase domain 53 147 1.5E-22 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 THITH_16530 6c4cf1cc4c1f1424550e81b2551d1895 287 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 15 267 3.4E-66 T 13-10-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 THITH_13020 c1f07f9ae92f72af7c2f0a3674ce4880 645 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 6 613 37.96 T 13-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 THITH_13020 c1f07f9ae92f72af7c2f0a3674ce4880 645 Gene3D G3DSA:1.20.58.760 402 603 2.8E-77 T 13-10-2018 THITH_13020 c1f07f9ae92f72af7c2f0a3674ce4880 645 Pfam PF06480 FtsH Extracellular 9 85 1.8E-10 T 13-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 THITH_13020 c1f07f9ae92f72af7c2f0a3674ce4880 645 Gene3D G3DSA:2.40.50.920 29 101 8.9E-9 T 13-10-2018 THITH_13020 c1f07f9ae92f72af7c2f0a3674ce4880 645 ProSitePatterns PS00674 AAA-protein family signature. 296 314 - T 13-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 THITH_13020 c1f07f9ae92f72af7c2f0a3674ce4880 645 Gene3D G3DSA:1.10.8.60 328 401 1.2E-29 T 13-10-2018 THITH_13020 c1f07f9ae92f72af7c2f0a3674ce4880 645 Pfam PF01434 Peptidase family M41 387 597 6.8E-86 T 13-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 THITH_13020 c1f07f9ae92f72af7c2f0a3674ce4880 645 SUPERFAMILY SSF140990 407 609 9.55E-80 T 13-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 THITH_13020 c1f07f9ae92f72af7c2f0a3674ce4880 645 SUPERFAMILY SSF52540 149 396 3.03E-73 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13020 c1f07f9ae92f72af7c2f0a3674ce4880 645 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 193 325 3.7E-45 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THITH_13020 c1f07f9ae92f72af7c2f0a3674ce4880 645 Gene3D G3DSA:3.40.50.300 141 327 6.4E-70 T 13-10-2018 THITH_13020 c1f07f9ae92f72af7c2f0a3674ce4880 645 SMART SM00382 189 328 2.0E-24 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_13020 c1f07f9ae92f72af7c2f0a3674ce4880 645 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 102 598 5.2E-246 T 13-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 THITH_02520 9937cdc09041d728ea9958a0c4adc0ea 269 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 7 258 3.5E-68 T 13-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THITH_02520 9937cdc09041d728ea9958a0c4adc0ea 269 SUPERFAMILY SSF53613 5 263 1.08E-67 T 13-10-2018 IPR029056 Ribokinase-like THITH_02520 9937cdc09041d728ea9958a0c4adc0ea 269 Gene3D G3DSA:3.40.1190.20 1 267 3.8E-88 T 13-10-2018 IPR029056 Ribokinase-like THITH_02520 9937cdc09041d728ea9958a0c4adc0ea 269 Pfam PF08543 Phosphomethylpyrimidine kinase 14 258 2.9E-76 T 13-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 THITH_06450 44d291530ab404a0a95887f21f73a345 427 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 423 2.0E-141 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 THITH_06450 44d291530ab404a0a95887f21f73a345 427 SUPERFAMILY SSF53383 1 424 1.71E-128 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_06450 44d291530ab404a0a95887f21f73a345 427 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 196 210 - T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 THITH_06450 44d291530ab404a0a95887f21f73a345 427 Gene3D G3DSA:3.40.640.10 1 285 2.0E-105 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_06450 44d291530ab404a0a95887f21f73a345 427 Gene3D G3DSA:3.90.1150.10 289 427 2.6E-50 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_06450 44d291530ab404a0a95887f21f73a345 427 PIRSF PIRSF001434 1 427 6.2E-133 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 THITH_06450 44d291530ab404a0a95887f21f73a345 427 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 2 424 2.1E-197 T 13-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 THITH_00925 6bf714508bf9448e8ecca38d69b76809 351 Hamap MF_01454 GTPase Obg [obg]. 2 334 48.088 T 13-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 THITH_00925 6bf714508bf9448e8ecca38d69b76809 351 ProSitePatterns PS00905 GTP1/OBG family signature. 213 226 - T 13-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 THITH_00925 6bf714508bf9448e8ecca38d69b76809 351 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 3 333 4.5E-142 T 13-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 THITH_00925 6bf714508bf9448e8ecca38d69b76809 351 PIRSF PIRSF002401 1 346 5.5E-132 T 13-10-2018 IPR035101 GTP-binding protein, Obg-type THITH_00925 6bf714508bf9448e8ecca38d69b76809 351 Gene3D G3DSA:3.40.50.300 159 338 1.1E-49 T 13-10-2018 THITH_00925 6bf714508bf9448e8ecca38d69b76809 351 Gene3D G3DSA:2.70.210.12 1 158 7.2E-61 T 13-10-2018 IPR036726 GTP1/OBG domain superfamily THITH_00925 6bf714508bf9448e8ecca38d69b76809 351 SUPERFAMILY SSF52540 151 331 7.76E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00925 6bf714508bf9448e8ecca38d69b76809 351 SUPERFAMILY SSF82051 2 158 8.5E-56 T 13-10-2018 IPR036726 GTP1/OBG domain superfamily THITH_00925 6bf714508bf9448e8ecca38d69b76809 351 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 211 226 4.4E-33 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_00925 6bf714508bf9448e8ecca38d69b76809 351 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 228 246 4.4E-33 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_00925 6bf714508bf9448e8ecca38d69b76809 351 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 4.4E-33 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_00925 6bf714508bf9448e8ecca38d69b76809 351 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 4.4E-33 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_00925 6bf714508bf9448e8ecca38d69b76809 351 Pfam PF01926 50S ribosome-binding GTPase 161 285 1.1E-21 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_00925 6bf714508bf9448e8ecca38d69b76809 351 Pfam PF01018 GTP1/OBG 4 158 8.4E-58 T 13-10-2018 IPR006169 GTP1/OBG domain THITH_00880 3a278f7d61dfbf2b4b4f5b1df27cae5a 180 Gene3D G3DSA:3.40.50.300 1 175 3.7E-18 T 13-10-2018 THITH_00880 3a278f7d61dfbf2b4b4f5b1df27cae5a 180 SUPERFAMILY SSF52540 4 170 1.36E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00880 3a278f7d61dfbf2b4b4f5b1df27cae5a 180 Pfam PF03029 Conserved hypothetical ATP binding protein 28 106 3.0E-7 T 13-10-2018 IPR004130 GPN-loop GTPase THITH_01125 f26dbfa6c34c62d4bdde38f1e0dbdab5 127 TIGRFAM TIGR01550 DOC_P1: death-on-curing family protein 8 93 1.1E-12 T 13-10-2018 IPR006440 Death on curing protein GO:0016301 THITH_01125 f26dbfa6c34c62d4bdde38f1e0dbdab5 127 SUPERFAMILY SSF140931 10 124 7.59E-10 T 13-10-2018 IPR036597 Fido-like domain superfamily THITH_01125 f26dbfa6c34c62d4bdde38f1e0dbdab5 127 Pfam PF02661 Fic/DOC family 9 81 2.1E-9 T 13-10-2018 IPR003812 Fido domain THITH_01125 f26dbfa6c34c62d4bdde38f1e0dbdab5 127 Gene3D G3DSA:1.20.120.1870 4 127 1.2E-29 T 13-10-2018 THITH_06105 92f279aeee0ce39b28a25514afe462a5 567 ProDom PD043552 KINASE KINASE/PHOSPHATASE ISOCITRATE DEHYDROGENASE 3.1.3.- IDH TRANSFERASE IDHK/P HYDROLASE ENZYME 1 563 3.0E-170 T 13-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 THITH_06105 92f279aeee0ce39b28a25514afe462a5 567 Hamap MF_00747 Isocitrate dehydrogenase kinase/phosphatase [aceK]. 1 564 41.882 T 13-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 THITH_06105 92f279aeee0ce39b28a25514afe462a5 567 Pfam PF06315 Isocitrate dehydrogenase kinase/phosphatase (AceK) 1 560 4.9E-249 T 13-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 THITH_06105 92f279aeee0ce39b28a25514afe462a5 567 PIRSF PIRSF000719 1 566 7.6E-226 T 13-10-2018 IPR010452 Isocitrate dehydrogenase kinasephosphatase GO:0005737|GO:0006006|GO:0008772|GO:0016791 THITH_13685 4daa83e2eb02293778ffc40a3efa2f2e 496 PIRSF PIRSF000110 2 492 3.2E-169 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THITH_13685 4daa83e2eb02293778ffc40a3efa2f2e 496 SUPERFAMILY SSF51735 5 193 3.54E-54 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_13685 4daa83e2eb02293778ffc40a3efa2f2e 496 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 180 186 - T 13-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THITH_13685 4daa83e2eb02293778ffc40a3efa2f2e 496 SUPERFAMILY SSF55347 180 489 9.16E-110 T 13-10-2018 THITH_13685 4daa83e2eb02293778ffc40a3efa2f2e 496 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 7 490 77.44 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THITH_13685 4daa83e2eb02293778ffc40a3efa2f2e 496 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 192 489 2.6E-111 T 13-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THITH_13685 4daa83e2eb02293778ffc40a3efa2f2e 496 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 146 159 9.1E-45 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THITH_13685 4daa83e2eb02293778ffc40a3efa2f2e 496 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 170 198 9.1E-45 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THITH_13685 4daa83e2eb02293778ffc40a3efa2f2e 496 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 222 239 9.1E-45 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THITH_13685 4daa83e2eb02293778ffc40a3efa2f2e 496 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 240 256 9.1E-45 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THITH_13685 4daa83e2eb02293778ffc40a3efa2f2e 496 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 331 357 9.1E-45 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THITH_13685 4daa83e2eb02293778ffc40a3efa2f2e 496 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 7 490 1.5E-172 T 13-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THITH_13685 4daa83e2eb02293778ffc40a3efa2f2e 496 Gene3D G3DSA:3.30.360.10 179 491 1.2E-118 T 13-10-2018 THITH_13685 4daa83e2eb02293778ffc40a3efa2f2e 496 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 11 190 8.8E-54 T 13-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 THITH_13685 4daa83e2eb02293778ffc40a3efa2f2e 496 Gene3D G3DSA:3.40.50.720 5 178 1.5E-44 T 13-10-2018 THITH_17240 a6ea62af58e129b408fa472894acf954 245 Pfam PF00857 Isochorismatase family 81 233 4.5E-33 T 13-10-2018 IPR000868 Isochorismatase-like GO:0003824 THITH_17240 a6ea62af58e129b408fa472894acf954 245 SUPERFAMILY SSF52499 30 238 5.36E-47 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 THITH_17240 a6ea62af58e129b408fa472894acf954 245 Gene3D G3DSA:3.40.50.850 17 245 3.0E-51 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 THITH_15295 41120b59ab1cd0e6aac7bc78300d2c26 264 Pfam PF13533 Biotin-lipoyl like 41 85 1.2E-9 T 13-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain THITH_15295 41120b59ab1cd0e6aac7bc78300d2c26 264 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 27 262 5.7E-37 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THITH_15295 41120b59ab1cd0e6aac7bc78300d2c26 264 Gene3D G3DSA:2.40.30.170 33 259 8.2E-38 T 13-10-2018 THITH_15295 41120b59ab1cd0e6aac7bc78300d2c26 264 Gene3D G3DSA:2.40.50.100 38 186 8.2E-38 T 13-10-2018 THITH_15295 41120b59ab1cd0e6aac7bc78300d2c26 264 Gene3D G3DSA:1.10.287.470 72 149 8.2E-38 T 13-10-2018 THITH_15295 41120b59ab1cd0e6aac7bc78300d2c26 264 SUPERFAMILY SSF111369 28 260 6.41E-22 T 13-10-2018 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 SUPERFAMILY SSF82693 39 132 6.28E-25 T 13-10-2018 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 TIGRFAM TIGR00915 2A0602: RND transporter, hydrophobe/amphiphile efflux-1 (HAE1) family 3 1025 0.0 T 13-10-2018 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 GO:0006855|GO:0015562|GO:0016021 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 Gene3D G3DSA:3.30.2090.10 719 807 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 Gene3D G3DSA:3.30.2090.10 180 277 0.0 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 SUPERFAMILY SSF82866 804 1026 1.31E-42 T 13-10-2018 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 SUPERFAMILY SSF82693 138 332 2.44E-25 T 13-10-2018 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 SUPERFAMILY SSF82714 184 273 1.96E-20 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 SUPERFAMILY SSF82714 720 804 2.49E-19 T 13-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 Gene3D G3DSA:3.30.70.1440 667 864 0.0 T 13-10-2018 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 Gene3D G3DSA:1.20.1640.10 511 1021 0.0 T 13-10-2018 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 SUPERFAMILY SSF82866 298 500 2.35E-52 T 13-10-2018 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 Gene3D G3DSA:3.30.70.1320 134 334 0.0 T 13-10-2018 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 SUPERFAMILY SSF82693 563 669 1.88E-26 T 13-10-2018 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 Gene3D G3DSA:1.20.1640.10 9 510 0.0 T 13-10-2018 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 PRINTS PR00702 Acriflavin resistance protein family signature 365 386 7.8E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 PRINTS PR00702 Acriflavin resistance protein family signature 550 567 7.8E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 PRINTS PR00702 Acriflavin resistance protein family signature 9 33 7.8E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 PRINTS PR00702 Acriflavin resistance protein family signature 338 361 7.8E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 PRINTS PR00702 Acriflavin resistance protein family signature 472 495 7.8E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 PRINTS PR00702 Acriflavin resistance protein family signature 37 55 7.8E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 PRINTS PR00702 Acriflavin resistance protein family signature 393 417 7.8E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 PRINTS PR00702 Acriflavin resistance protein family signature 447 470 7.8E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 PRINTS PR00702 Acriflavin resistance protein family signature 619 633 7.8E-90 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 Gene3D G3DSA:3.30.70.1430 39 815 0.0 T 13-10-2018 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 Gene3D G3DSA:3.30.70.1430 565 666 0.0 T 13-10-2018 THITH_08800 0f26e50f240b005d3586bf846e7ae430 1046 Pfam PF00873 AcrB/AcrD/AcrF family 3 1024 0.0 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_04870 8f79e20b60eb51dec625584e67b9df04 119 Pfam PF17228 Sulphur globule protein 40 115 7.6E-7 T 13-10-2018 IPR035173 Sulphur globule protein THITH_06425 56f62192fc9d1c053c0135e3b6b413f9 474 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 271 282 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_06425 56f62192fc9d1c053c0135e3b6b413f9 474 Gene3D G3DSA:2.60.40.10 355 473 2.3E-27 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_06425 56f62192fc9d1c053c0135e3b6b413f9 474 SUPERFAMILY SSF54862 104 342 8.37E-33 T 13-10-2018 THITH_06425 56f62192fc9d1c053c0135e3b6b413f9 474 Pfam PF13746 4Fe-4S dicluster domain 218 323 4.2E-43 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_06425 56f62192fc9d1c053c0135e3b6b413f9 474 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 40 472 2.8E-163 T 13-10-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 THITH_06425 56f62192fc9d1c053c0135e3b6b413f9 474 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 353 472 5.9E-28 T 13-10-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain THITH_06425 56f62192fc9d1c053c0135e3b6b413f9 474 Pfam PF12801 4Fe-4S binding domain 94 135 8.4E-10 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_11730 afe90693bfc1b07aef6b57e0b5955c9c 299 SUPERFAMILY SSF53850 55 247 5.44E-20 T 13-10-2018 THITH_11730 afe90693bfc1b07aef6b57e0b5955c9c 299 Gene3D G3DSA:3.40.190.10 42 265 1.4E-41 T 13-10-2018 THITH_11730 afe90693bfc1b07aef6b57e0b5955c9c 299 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 42 283 1.5E-45 T 13-10-2018 THITH_11730 afe90693bfc1b07aef6b57e0b5955c9c 299 TIGRFAM TIGR01098 3A0109s03R: phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein 1 257 6.5E-44 T 13-10-2018 IPR005770 Phosphate/phosphite/phosphonate ABC transporter, periplasmic binding protein GO:0043190|GO:0055085 THITH_11730 afe90693bfc1b07aef6b57e0b5955c9c 299 Gene3D G3DSA:3.40.190.10 118 233 1.4E-41 T 13-10-2018 THITH_17420 3d6493bfcee3a0362a211cd841fa0a54 448 Pfam PF09242 Flavocytochrome c sulphide dehydrogenase, flavin-binding 380 447 5.8E-18 T 13-10-2018 IPR015323 Flavocytochrome c sulphide dehydrogenase, flavin-binding GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 THITH_17420 3d6493bfcee3a0362a211cd841fa0a54 448 Gene3D G3DSA:3.50.50.60 146 305 2.1E-92 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_17420 3d6493bfcee3a0362a211cd841fa0a54 448 SUPERFAMILY SSF55424 380 447 2.39E-8 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THITH_17420 3d6493bfcee3a0362a211cd841fa0a54 448 Gene3D G3DSA:3.90.760.10 378 448 1.4E-9 T 13-10-2018 IPR037092 Flavocytochrome c sulphide dehydrogenase, flavin-binding domain superfamily GO:0016491|GO:0050660|GO:0055114 KEGG: 00920+1.8.2.3|MetaCyc: PWY-5274 THITH_17420 3d6493bfcee3a0362a211cd841fa0a54 448 SUPERFAMILY SSF51905 150 305 1.08E-28 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_17420 3d6493bfcee3a0362a211cd841fa0a54 448 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 32 145 1.8E-8 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THITH_17420 3d6493bfcee3a0362a211cd841fa0a54 448 Gene3D G3DSA:3.50.50.60 33 367 2.1E-92 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_17420 3d6493bfcee3a0362a211cd841fa0a54 448 SUPERFAMILY SSF51905 32 375 1.34E-25 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_10380 2a0f282cdb6e19e43e21b4ad2bc70dc0 164 SUPERFAMILY SSF56770 13 157 4.45E-61 T 13-10-2018 THITH_10380 2a0f282cdb6e19e43e21b4ad2bc70dc0 164 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 120 136 - T 13-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10380 2a0f282cdb6e19e43e21b4ad2bc70dc0 164 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 14 154 3.4E-63 T 13-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10380 2a0f282cdb6e19e43e21b4ad2bc70dc0 164 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 39 148 5.9E-23 T 13-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10380 2a0f282cdb6e19e43e21b4ad2bc70dc0 164 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 9 153 39.96 T 13-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10380 2a0f282cdb6e19e43e21b4ad2bc70dc0 164 Gene3D G3DSA:3.40.50.12280 1 163 7.9E-65 T 13-10-2018 THITH_04660 637e66e8a8a9c66fecbc863c80e09a70 124 Pfam PF01850 PIN domain 4 117 1.3E-11 T 13-10-2018 IPR002716 PIN domain THITH_04660 637e66e8a8a9c66fecbc863c80e09a70 124 Gene3D G3DSA:3.40.50.1010 1 118 4.9E-8 T 13-10-2018 THITH_04660 637e66e8a8a9c66fecbc863c80e09a70 124 SUPERFAMILY SSF88723 2 117 8.69E-16 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_02860 d333a6eb4f09ea1fdfdd16bae906d403 125 Pfam PF02635 DsrE/DsrF-like family 26 105 4.5E-7 T 13-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THITH_02860 d333a6eb4f09ea1fdfdd16bae906d403 125 Gene3D G3DSA:3.40.1260.10 1 125 2.0E-22 T 13-10-2018 IPR027396 DsrEFH-like THITH_02860 d333a6eb4f09ea1fdfdd16bae906d403 125 SUPERFAMILY SSF75169 11 119 9.08E-11 T 13-10-2018 IPR027396 DsrEFH-like THITH_17280 703c19ee8d46eeb293141aaea25713f6 270 SUPERFAMILY SSF56219 1 253 2.09E-75 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily THITH_17280 703c19ee8d46eeb293141aaea25713f6 270 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 246 1.5E-21 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase THITH_17280 703c19ee8d46eeb293141aaea25713f6 270 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 1 251 1.4E-67 T 13-10-2018 THITH_17280 703c19ee8d46eeb293141aaea25713f6 270 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 13-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 THITH_17280 703c19ee8d46eeb293141aaea25713f6 270 Gene3D G3DSA:3.60.10.10 1 254 1.4E-82 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily THITH_17280 703c19ee8d46eeb293141aaea25713f6 270 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 252 4.3E-75 T 13-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 THITH_07145 c64ff815800e81314c97fdb371ae5a49 301 SMART SM00382 28 219 2.6E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_07145 c64ff815800e81314c97fdb371ae5a49 301 SUPERFAMILY SSF52540 3 223 1.49E-67 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_07145 c64ff815800e81314c97fdb371ae5a49 301 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_07145 c64ff815800e81314c97fdb371ae5a49 301 Gene3D G3DSA:3.40.50.300 2 231 1.5E-72 T 13-10-2018 THITH_07145 c64ff815800e81314c97fdb371ae5a49 301 Pfam PF00005 ABC transporter 20 162 4.6E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_15705 69995ee2c546f1cf8a5a9de8bb690cf7 208 Pfam PF07963 Prokaryotic N-terminal methylation motif 16 39 2.2E-7 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_15705 69995ee2c546f1cf8a5a9de8bb690cf7 208 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 17 40 6.7E-5 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_13660 771793e26b98059e0100673ac7b5b66f 163 Pfam PF03692 Putative zinc- or iron-chelating domain 22 90 5.2E-6 T 13-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein THITH_13660 771793e26b98059e0100673ac7b5b66f 163 Hamap MF_00676 UPF0260 protein YcgN [ycgN]. 1 145 36.21 T 13-10-2018 IPR008228 Uncharacterised conserved protein UCP006173 THITH_13660 771793e26b98059e0100673ac7b5b66f 163 PIRSF PIRSF006173 1 145 3.3E-56 T 13-10-2018 IPR008228 Uncharacterised conserved protein UCP006173 THITH_06600 b54ea28915cb379343d29a431c4f9a50 341 Pfam PF02371 Transposase IS116/IS110/IS902 family 212 289 6.4E-16 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THITH_06600 b54ea28915cb379343d29a431c4f9a50 341 Pfam PF01548 Transposase 7 147 1.1E-18 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THITH_03780 1c4b577089de2ed9911adf9933cabe64 245 Pfam PF12119 Protein of unknown function (DUF3581) 6 223 1.4E-90 T 13-10-2018 IPR021974 Protein of unknown function DUF3581 THITH_15945 e1f7add86cfd992739ecd4ad6992e538 332 SUPERFAMILY SSF55347 150 313 6.25E-75 T 13-10-2018 THITH_15945 e1f7add86cfd992739ecd4ad6992e538 332 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 13-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15945 e1f7add86cfd992739ecd4ad6992e538 332 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 103 1.8E-40 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15945 e1f7add86cfd992739ecd4ad6992e538 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 7.7E-43 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15945 e1f7add86cfd992739ecd4ad6992e538 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 110 123 7.7E-43 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15945 e1f7add86cfd992739ecd4ad6992e538 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 7.7E-43 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15945 e1f7add86cfd992739ecd4ad6992e538 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 7.7E-43 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15945 e1f7add86cfd992739ecd4ad6992e538 332 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 7.7E-43 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15945 e1f7add86cfd992739ecd4ad6992e538 332 SMART SM00846 3 151 3.5E-97 T 13-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15945 e1f7add86cfd992739ecd4ad6992e538 332 SUPERFAMILY SSF51735 3 167 2.69E-65 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_15945 e1f7add86cfd992739ecd4ad6992e538 332 Gene3D G3DSA:3.40.50.720 4 327 2.0E-149 T 13-10-2018 THITH_15945 e1f7add86cfd992739ecd4ad6992e538 332 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 2.0E-133 T 13-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15945 e1f7add86cfd992739ecd4ad6992e538 332 PIRSF PIRSF000149 1 332 9.4E-130 T 13-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_15945 e1f7add86cfd992739ecd4ad6992e538 332 Gene3D G3DSA:3.30.360.10 150 315 2.0E-149 T 13-10-2018 THITH_15945 e1f7add86cfd992739ecd4ad6992e538 332 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 313 9.1E-68 T 13-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_10225 ad33eff25be2c21d299367d0cef8cc33 188 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 2 173 1.6E-76 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 THITH_10225 ad33eff25be2c21d299367d0cef8cc33 188 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 177 2.0E-62 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 THITH_10225 ad33eff25be2c21d299367d0cef8cc33 188 SUPERFAMILY SSF51182 1 177 2.08E-75 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily THITH_10225 ad33eff25be2c21d299367d0cef8cc33 188 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 5 172 4.8E-73 T 13-10-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 THITH_10225 ad33eff25be2c21d299367d0cef8cc33 188 Gene3D G3DSA:2.60.120.10 1 187 1.7E-71 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_02890 737c9eecb7a930ff65f3c58bfd318670 171 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 106 125 4.9E-38 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THITH_02890 737c9eecb7a930ff65f3c58bfd318670 171 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 60 76 4.9E-38 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THITH_02890 737c9eecb7a930ff65f3c58bfd318670 171 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 4 17 4.9E-38 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THITH_02890 737c9eecb7a930ff65f3c58bfd318670 171 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 82 98 4.9E-38 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THITH_02890 737c9eecb7a930ff65f3c58bfd318670 171 PRINTS PR00696 Crossover junction endodeoxyribonuclease RUVC signature 137 149 4.9E-38 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THITH_02890 737c9eecb7a930ff65f3c58bfd318670 171 Pfam PF02075 Crossover junction endodeoxyribonuclease RuvC 3 149 3.3E-51 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THITH_02890 737c9eecb7a930ff65f3c58bfd318670 171 Gene3D G3DSA:3.30.420.10 3 157 6.6E-47 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_02890 737c9eecb7a930ff65f3c58bfd318670 171 SUPERFAMILY SSF53098 1 154 1.9E-50 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_02890 737c9eecb7a930ff65f3c58bfd318670 171 Hamap MF_00034 Crossover junction endodeoxyribonuclease RuvC [ruvC]. 1 152 45.129 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THITH_02890 737c9eecb7a930ff65f3c58bfd318670 171 TIGRFAM TIGR00228 ruvC: crossover junction endodeoxyribonuclease RuvC 3 154 8.4E-53 T 13-10-2018 IPR002176 Crossover junction endodeoxyribonuclease RuvC GO:0004520|GO:0006281|GO:0006310 THITH_02890 737c9eecb7a930ff65f3c58bfd318670 171 ProSitePatterns PS01321 Crossover junction endodeoxyribonuclease ruvC signature. 112 146 - T 13-10-2018 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site GO:0008821 THITH_09290 6bf8f4764e3bb1476e74061ef964dccb 441 Gene3D G3DSA:3.30.70.2950 354 434 1.2E-6 T 13-10-2018 THITH_09290 6bf8f4764e3bb1476e74061ef964dccb 441 Pfam PF09700 CRISPR-associated protein (Cas_Cmr3) 54 434 5.7E-77 T 13-10-2018 IPR019117 CRISPR-associated protein, Cmr3 THITH_07340 8368090e4584984a01d751df18a23b26 196 Pfam PF00881 Nitroreductase family 18 158 7.1E-15 T 13-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 THITH_07340 8368090e4584984a01d751df18a23b26 196 SUPERFAMILY SSF55469 10 195 1.96E-44 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THITH_07340 8368090e4584984a01d751df18a23b26 196 Gene3D G3DSA:3.40.109.10 2 194 2.3E-30 T 13-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 THITH_07340 8368090e4584984a01d751df18a23b26 196 Hamap MF_01204 Probable malonic semialdehyde reductase RutE [rutE]. 2 196 47.515 T 13-10-2018 IPR023936 NADH dehydrogenase/NAD(P)H nitroreductase, putative, RutE GO:0016491|GO:0055114 THITH_06710 65967dcbde22ecc5d1b8c6c8ed34f5ad 261 SUPERFAMILY SSF53067 112 250 8.55E-23 T 13-10-2018 THITH_06710 65967dcbde22ecc5d1b8c6c8ed34f5ad 261 Gene3D G3DSA:3.30.420.40 1 246 3.4E-53 T 13-10-2018 THITH_06710 65967dcbde22ecc5d1b8c6c8ed34f5ad 261 Pfam PF03309 Type III pantothenate kinase 3 203 3.2E-27 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 THITH_06710 65967dcbde22ecc5d1b8c6c8ed34f5ad 261 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 254 14.598 T 13-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 THITH_06710 65967dcbde22ecc5d1b8c6c8ed34f5ad 261 SUPERFAMILY SSF53067 1 106 2.1E-8 T 13-10-2018 THITH_06710 65967dcbde22ecc5d1b8c6c8ed34f5ad 261 Gene3D G3DSA:3.30.420.490 113 239 3.4E-53 T 13-10-2018 THITH_11220 624243d57d53dc949a599ef42946ada7 500 SUPERFAMILY SSF75304 6 472 5.76E-119 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THITH_11220 624243d57d53dc949a599ef42946ada7 500 Pfam PF01425 Amidase 22 462 2.7E-91 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THITH_11220 624243d57d53dc949a599ef42946ada7 500 Gene3D G3DSA:3.90.1300.10 1 477 5.5E-118 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THITH_04025 1bbabf90818014c36fafa30309affead 592 Pfam PF02272 DHHA1 domain 332 460 3.2E-13 T 13-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 THITH_04025 1bbabf90818014c36fafa30309affead 592 Gene3D G3DSA:3.10.310.30 338 478 7.0E-25 T 13-10-2018 THITH_04025 1bbabf90818014c36fafa30309affead 592 Gene3D G3DSA:3.90.1640.30 55 336 3.2E-61 T 13-10-2018 THITH_04025 1bbabf90818014c36fafa30309affead 592 SUPERFAMILY SSF64182 55 475 8.02E-82 T 13-10-2018 IPR038763 DHH phosphoesterase superfamily THITH_09375 a348e9f9b91d8eea17d39a2633bfb206 413 SUPERFAMILY SSF53633 4 242 2.75E-75 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THITH_09375 a348e9f9b91d8eea17d39a2633bfb206 413 Gene3D G3DSA:3.30.70.260 254 402 5.3E-58 T 13-10-2018 THITH_09375 a348e9f9b91d8eea17d39a2633bfb206 413 SUPERFAMILY SSF55021 248 325 1.29E-18 T 13-10-2018 THITH_09375 a348e9f9b91d8eea17d39a2633bfb206 413 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 64 401 1.1E-120 T 13-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 THITH_09375 a348e9f9b91d8eea17d39a2633bfb206 413 Gene3D G3DSA:3.30.70.260 260 337 5.3E-58 T 13-10-2018 THITH_09375 a348e9f9b91d8eea17d39a2633bfb206 413 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 1 402 1.0E-131 T 13-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 THITH_09375 a348e9f9b91d8eea17d39a2633bfb206 413 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 13-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 THITH_09375 a348e9f9b91d8eea17d39a2633bfb206 413 Pfam PF01842 ACT domain 266 324 1.1E-9 T 13-10-2018 IPR002912 ACT domain THITH_09375 a348e9f9b91d8eea17d39a2633bfb206 413 Pfam PF00696 Amino acid kinase family 3 229 1.6E-53 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 THITH_09375 a348e9f9b91d8eea17d39a2633bfb206 413 Pfam PF13840 ACT domain 338 398 2.1E-14 T 13-10-2018 IPR027795 CASTOR, ACT domain THITH_09375 a348e9f9b91d8eea17d39a2633bfb206 413 PIRSF PIRSF000726 1 63 2.6E-18 T 13-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 THITH_09375 a348e9f9b91d8eea17d39a2633bfb206 413 PIRSF PIRSF000726 60 409 1.9E-146 T 13-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 THITH_09375 a348e9f9b91d8eea17d39a2633bfb206 413 SUPERFAMILY SSF55021 328 403 4.23E-25 T 13-10-2018 THITH_09375 a348e9f9b91d8eea17d39a2633bfb206 413 Gene3D G3DSA:3.40.1160.10 1 253 1.6E-88 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THITH_16440 33c31adf2af58dbbb6e5b3882f40ea15 449 SUPERFAMILY SSF63411 258 446 5.83E-48 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THITH_16440 33c31adf2af58dbbb6e5b3882f40ea15 449 Gene3D G3DSA:3.30.830.10 42 252 4.8E-49 T 13-10-2018 THITH_16440 33c31adf2af58dbbb6e5b3882f40ea15 449 SUPERFAMILY SSF63411 35 243 9.67E-44 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THITH_16440 33c31adf2af58dbbb6e5b3882f40ea15 449 Pfam PF05193 Peptidase M16 inactive domain 205 380 5.2E-36 T 13-10-2018 IPR007863 Peptidase M16, C-terminal THITH_16440 33c31adf2af58dbbb6e5b3882f40ea15 449 Pfam PF00675 Insulinase (Peptidase family M16) 58 198 9.7E-10 T 13-10-2018 IPR011765 Peptidase M16, N-terminal THITH_16440 33c31adf2af58dbbb6e5b3882f40ea15 449 Gene3D G3DSA:3.30.830.10 259 449 4.2E-55 T 13-10-2018 THITH_04290 f7451a6e050695aae5724216fe5c651e 593 SUPERFAMILY SSF51905 21 364 1.11E-28 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_04290 f7451a6e050695aae5724216fe5c651e 593 Pfam PF01494 FAD binding domain 21 235 2.1E-9 T 13-10-2018 IPR002938 FAD-binding domain GO:0071949 THITH_04290 f7451a6e050695aae5724216fe5c651e 593 Gene3D G3DSA:3.50.50.60 15 416 1.9E-68 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_05205 fb971bd771287f947af02307b1fbd983 665 SMART SM00487 18 244 3.4E-7 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_05205 fb971bd771287f947af02307b1fbd983 665 Pfam PF00271 Helicase conserved C-terminal domain 345 389 1.0E-4 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_05205 fb971bd771287f947af02307b1fbd983 665 Pfam PF00270 DEAD/DEAH box helicase 38 214 8.3E-8 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THITH_05205 fb971bd771287f947af02307b1fbd983 665 Gene3D G3DSA:3.40.50.300 315 460 9.6E-9 T 13-10-2018 THITH_05205 fb971bd771287f947af02307b1fbd983 665 Gene3D G3DSA:3.40.50.300 16 223 4.3E-15 T 13-10-2018 THITH_05205 fb971bd771287f947af02307b1fbd983 665 SUPERFAMILY SSF52540 33 400 1.64E-25 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_11185 9f5f48ad2a2ecf18e2050a4a1bef1abc 389 Pfam PF13817 IS66 C-terminal element 337 375 2.5E-12 T 13-10-2018 IPR039552 Transposase IS66, C-terminal THITH_11185 9f5f48ad2a2ecf18e2050a4a1bef1abc 389 Pfam PF03050 Transposase IS66 family 40 331 2.7E-96 T 13-10-2018 IPR004291 Transposase, IS66 THITH_04760 84031ffefa37c694576d9555829245a8 260 Gene3D G3DSA:3.40.50.150 2 253 7.8E-60 T 13-10-2018 THITH_04760 84031ffefa37c694576d9555829245a8 260 SUPERFAMILY SSF53335 27 254 3.38E-36 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_04760 84031ffefa37c694576d9555829245a8 260 Pfam PF13649 Methyltransferase domain 46 140 5.8E-17 T 13-10-2018 THITH_02110 1114767c25461e9f3dff87134df1e41e 965 PIRSF PIRSF036643 478 636 1.7E-11 T 13-10-2018 THITH_02110 1114767c25461e9f3dff87134df1e41e 965 PIRSF PIRSF036643 32 444 4.3E-103 T 13-10-2018 THITH_02110 1114767c25461e9f3dff87134df1e41e 965 PIRSF PIRSF036643 797 916 5.2E-12 T 13-10-2018 THITH_02110 1114767c25461e9f3dff87134df1e41e 965 SUPERFAMILY SSF50692 804 965 4.07E-34 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily THITH_02110 1114767c25461e9f3dff87134df1e41e 965 Gene3D G3DSA:2.20.25.90 71 123 1.1E-12 T 13-10-2018 THITH_02110 1114767c25461e9f3dff87134df1e41e 965 Gene3D G3DSA:2.40.40.20 780 965 7.0E-37 T 13-10-2018 THITH_02110 1114767c25461e9f3dff87134df1e41e 965 Pfam PF00384 Molybdopterin oxidoreductase 128 583 4.3E-55 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_02110 1114767c25461e9f3dff87134df1e41e 965 SMART SM00926 71 125 2.9E-14 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_02110 1114767c25461e9f3dff87134df1e41e 965 Gene3D G3DSA:3.40.50.740 137 630 7.1E-130 T 13-10-2018 THITH_02110 1114767c25461e9f3dff87134df1e41e 965 Gene3D G3DSA:3.40.228.10 205 403 7.1E-130 T 13-10-2018 THITH_02110 1114767c25461e9f3dff87134df1e41e 965 SUPERFAMILY SSF53706 70 676 1.23E-200 T 13-10-2018 THITH_02110 1114767c25461e9f3dff87134df1e41e 965 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 76 93 - T 13-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 THITH_02110 1114767c25461e9f3dff87134df1e41e 965 Pfam PF01568 Molydopterin dinucleotide binding domain 835 954 2.6E-15 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 THITH_02110 1114767c25461e9f3dff87134df1e41e 965 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 72 122 5.7E-11 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_05670 7782b42035809f22a56bdb4b3eca0936 106 SUPERFAMILY SSF47413 18 101 1.26E-21 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 THITH_05670 7782b42035809f22a56bdb4b3eca0936 106 Gene3D G3DSA:1.10.260.40 18 81 3.6E-22 T 13-10-2018 THITH_05670 7782b42035809f22a56bdb4b3eca0936 106 SMART SM00530 32 88 0.0032 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_05670 7782b42035809f22a56bdb4b3eca0936 106 Pfam PF13744 Helix-turn-helix domain 11 90 8.6E-29 T 13-10-2018 IPR039554 HigA2-like, helix-turn-helix domain THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 SUPERFAMILY SSF51419 26 282 1.6E-76 T 13-10-2018 IPR029066 PLP-binding barrel THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 30 368 2.5E-24 T 13-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 7 410 5.2E-151 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 SUPERFAMILY SSF50621 253 411 3.77E-51 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 228 241 - T 13-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 Gene3D G3DSA:2.40.37.10 16 407 5.5E-147 T 13-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 75 92 1.6E-29 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 164 173 1.6E-29 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 298 316 1.6E-29 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 PRINTS PR01181 Diaminopimelate decarboxylase signature 378 400 1.6E-29 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 Gene3D G3DSA:3.20.20.10 34 275 5.5E-147 T 13-10-2018 IPR029066 PLP-binding barrel THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 270 289 1.0E-25 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 368 381 1.0E-25 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 57 75 1.0E-25 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 77 89 1.0E-25 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 190 203 1.0E-25 T 13-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 35 280 7.8E-69 T 13-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 57 75 - T 13-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site THITH_00500 7dc1086047942d7dcb346990b8abe0d0 417 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 15 411 40.491 T 13-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 THITH_04285 ea97088580f6212ab1461e70de25ac7d 165 Hamap MF_01632 Chorismate pyruvate-lyase [ubiC]. 1 161 25.245 T 13-10-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745|MetaCyc: PWY-7929|MetaCyc: PWY-7934|MetaCyc: PWY-7935 THITH_04285 ea97088580f6212ab1461e70de25ac7d 165 SUPERFAMILY SSF64288 2 160 1.18E-41 T 13-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily THITH_04285 ea97088580f6212ab1461e70de25ac7d 165 Pfam PF04345 Chorismate lyase 2 160 5.8E-27 T 13-10-2018 IPR007440 Chorismate--pyruvate lyase GO:0005737|GO:0006744|GO:0008813 KEGG: 00130+4.1.3.40|MetaCyc: PWY-5755|MetaCyc: PWY-5870|MetaCyc: PWY-6148|MetaCyc: PWY-7742|MetaCyc: PWY-7745|MetaCyc: PWY-7929|MetaCyc: PWY-7934|MetaCyc: PWY-7935 THITH_04285 ea97088580f6212ab1461e70de25ac7d 165 Gene3D G3DSA:3.40.1410.10 1 158 1.3E-46 T 13-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily THITH_06285 8e0a48fb212d100cc55236635c363a99 347 Gene3D G3DSA:3.40.718.10 5 331 1.0E-121 T 13-10-2018 THITH_06285 8e0a48fb212d100cc55236635c363a99 347 SUPERFAMILY SSF53659 8 331 3.9E-112 T 13-10-2018 THITH_06285 8e0a48fb212d100cc55236635c363a99 347 Hamap MF_00536 4-hydroxythreonine-4-phosphate dehydrogenase [pdxA]. 7 331 36.485 T 13-10-2018 IPR037510 4-hydroxythreonine-4-phosphate dehydrogenase GO:0042823|GO:0050570 KEGG: 00750+1.1.1.262 THITH_06285 8e0a48fb212d100cc55236635c363a99 347 TIGRFAM TIGR00557 pdxA: 4-hydroxythreonine-4-phosphate dehydrogenase PdxA 9 327 1.7E-123 T 13-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 THITH_06285 8e0a48fb212d100cc55236635c363a99 347 Pfam PF04166 Pyridoxal phosphate biosynthetic protein PdxA 36 324 3.2E-104 T 13-10-2018 IPR005255 PdxA family GO:0051287|GO:0055114 KEGG: 00750+1.1.1.262 THITH_01475 e3a2c96fcf54500615b042c13ec6446f 143 Gene3D G3DSA:2.60.40.790 4 142 8.0E-40 T 13-10-2018 IPR008978 HSP20-like chaperone THITH_01475 e3a2c96fcf54500615b042c13ec6446f 143 Pfam PF00011 Hsp20/alpha crystallin family 42 141 1.6E-25 T 13-10-2018 IPR002068 Alpha crystallin/Hsp20 domain THITH_01475 e3a2c96fcf54500615b042c13ec6446f 143 SUPERFAMILY SSF49764 27 142 7.32E-41 T 13-10-2018 IPR008978 HSP20-like chaperone THITH_12720 43dd0d5ea1f6f48b33b4742e82e3e19b 298 Gene3D G3DSA:3.40.91.100 130 292 3.7E-7 T 13-10-2018 THITH_12720 43dd0d5ea1f6f48b33b4742e82e3e19b 298 Pfam PF04471 Restriction endonuclease 153 272 7.8E-36 T 13-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 THITH_12720 43dd0d5ea1f6f48b33b4742e82e3e19b 298 SUPERFAMILY SSF52980 157 276 5.9E-18 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_12720 43dd0d5ea1f6f48b33b4742e82e3e19b 298 Gene3D G3DSA:1.10.10.10 40 98 4.2E-5 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_12720 43dd0d5ea1f6f48b33b4742e82e3e19b 298 Pfam PF14338 Mrr N-terminal domain 6 91 1.4E-32 T 13-10-2018 IPR025745 Restriction system protein Mrr-like N-terminal domain THITH_11270 031a91e0416726892c7c77a33ecf62d4 577 Gene3D G3DSA:2.60.40.10 1 83 8.2E-23 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_11270 031a91e0416726892c7c77a33ecf62d4 577 PIRSF PIRSF006337 2 576 5.2E-232 T 13-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 THITH_11270 031a91e0416726892c7c77a33ecf62d4 577 SUPERFAMILY SSF81296 3 78 9.8E-16 T 13-10-2018 IPR014756 Immunoglobulin E-set THITH_11270 031a91e0416726892c7c77a33ecf62d4 577 Gene3D G3DSA:3.20.20.80 87 496 3.9E-179 T 13-10-2018 THITH_11270 031a91e0416726892c7c77a33ecf62d4 577 Pfam PF00128 Alpha amylase, catalytic domain 109 192 5.0E-15 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THITH_11270 031a91e0416726892c7c77a33ecf62d4 577 Gene3D G3DSA:1.10.10.760 428 468 3.9E-179 T 13-10-2018 THITH_11270 031a91e0416726892c7c77a33ecf62d4 577 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 5 534 7.1E-231 T 13-10-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|MetaCyc: PWY-2661 THITH_11270 031a91e0416726892c7c77a33ecf62d4 577 SUPERFAMILY SSF51445 75 502 8.6E-120 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily THITH_11270 031a91e0416726892c7c77a33ecf62d4 577 SMART SM00642 99 456 5.7E-12 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THITH_11270 031a91e0416726892c7c77a33ecf62d4 577 Pfam PF11941 Domain of unknown function (DUF3459) 487 574 1.8E-12 T 13-10-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) THITH_11270 031a91e0416726892c7c77a33ecf62d4 577 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 4 54 2.2E-4 T 13-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 THITH_08680 8bb3a797a3bee654646546ed0eedf2e2 284 Gene3D G3DSA:3.40.190.100 113 219 3.1E-105 T 13-10-2018 THITH_08680 8bb3a797a3bee654646546ed0eedf2e2 284 Gene3D G3DSA:3.40.190.10 33 283 3.1E-105 T 13-10-2018 THITH_08680 8bb3a797a3bee654646546ed0eedf2e2 284 SUPERFAMILY SSF53850 24 284 6.91E-83 T 13-10-2018 THITH_08680 8bb3a797a3bee654646546ed0eedf2e2 284 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 31 273 3.5E-66 T 13-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 THITH_09030 ddb3c33f0c8306de1fc616aa92a76415 316 SMART SM00382 30 215 8.5E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_09030 ddb3c33f0c8306de1fc616aa92a76415 316 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_09030 ddb3c33f0c8306de1fc616aa92a76415 316 Gene3D G3DSA:3.40.50.300 1 241 2.2E-66 T 13-10-2018 THITH_09030 ddb3c33f0c8306de1fc616aa92a76415 316 Pfam PF00005 ABC transporter 21 165 7.2E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_09030 ddb3c33f0c8306de1fc616aa92a76415 316 SUPERFAMILY SSF52540 4 234 1.84E-62 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_09880 54d981242eebd0f1a2e0d1ad51cf7ad7 408 SMART SM00382 50 228 3.4E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_09880 54d981242eebd0f1a2e0d1ad51cf7ad7 408 Gene3D G3DSA:3.40.50.300 29 245 2.9E-45 T 13-10-2018 THITH_09880 54d981242eebd0f1a2e0d1ad51cf7ad7 408 Pfam PF14524 Wzt C-terminal domain 262 400 3.8E-34 T 13-10-2018 IPR029439 Wzt, C-terminal THITH_09880 54d981242eebd0f1a2e0d1ad51cf7ad7 408 SUPERFAMILY SSF52540 38 234 3.22E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_09880 54d981242eebd0f1a2e0d1ad51cf7ad7 408 Gene3D G3DSA:2.70.50.60 259 396 4.3E-17 T 13-10-2018 THITH_09880 54d981242eebd0f1a2e0d1ad51cf7ad7 408 Pfam PF00005 ABC transporter 41 173 9.3E-19 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_09880 54d981242eebd0f1a2e0d1ad51cf7ad7 408 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_01885 e6125bf9785c40af65ebf83950f7cd24 1075 SUPERFAMILY SSF52540 274 523 3.99E-24 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01885 e6125bf9785c40af65ebf83950f7cd24 1075 SMART SM00487 300 498 1.3E-6 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_01885 e6125bf9785c40af65ebf83950f7cd24 1075 Pfam PF11867 Domain of unknown function (DUF3387) 778 965 2.8E-7 T 13-10-2018 IPR021810 Protein of unknown function DUF3387 THITH_01885 e6125bf9785c40af65ebf83950f7cd24 1075 Gene3D G3DSA:3.90.1570.50 84 235 7.5E-22 T 13-10-2018 THITH_01885 e6125bf9785c40af65ebf83950f7cd24 1075 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 6 216 2.4E-36 T 13-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 THITH_01885 e6125bf9785c40af65ebf83950f7cd24 1075 Gene3D G3DSA:3.40.50.300 304 486 1.3E-47 T 13-10-2018 THITH_01885 e6125bf9785c40af65ebf83950f7cd24 1075 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 16 734 3.3E-142 T 13-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 THITH_01885 e6125bf9785c40af65ebf83950f7cd24 1075 Gene3D G3DSA:3.40.50.300 487 742 3.7E-32 T 13-10-2018 THITH_01885 e6125bf9785c40af65ebf83950f7cd24 1075 Pfam PF04851 Type III restriction enzyme, res subunit 305 467 3.3E-14 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THITH_08710 4656110ab3d577f7316b35a02f1af51d 337 SUPERFAMILY SSF52540 21 196 4.97E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_08710 4656110ab3d577f7316b35a02f1af51d 337 Pfam PF13177 DNA polymerase III, delta subunit 25 180 9.6E-36 T 13-10-2018 THITH_08710 4656110ab3d577f7316b35a02f1af51d 337 Gene3D G3DSA:3.40.50.300 18 181 2.3E-46 T 13-10-2018 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 Gene3D G3DSA:3.30.1370.10 549 620 2.2E-21 T 13-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 PIRSF PIRSF005499 1 694 5.9E-303 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 SMART SM00316 619 689 7.7E-26 T 13-10-2018 IPR022967 RNA-binding domain, S1 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 8 691 0.0 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 SUPERFAMILY SSF54791 551 628 4.36E-17 T 13-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 1 692 31.29 T 13-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 Gene3D G3DSA:3.30.230.70 231 548 1.1E-119 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 SUPERFAMILY SSF55666 143 234 1.68E-29 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 SUPERFAMILY SSF54211 3 142 1.32E-50 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 SUPERFAMILY SSF54211 290 487 4.81E-51 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 Pfam PF00013 KH domain 556 613 6.1E-10 T 13-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 Pfam PF01138 3' exoribonuclease family, domain 1 13 142 2.7E-19 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 Pfam PF01138 3' exoribonuclease family, domain 1 323 455 1.1E-23 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 240 319 1.3E-21 T 13-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 SMART SM00322 551 616 2.1E-13 T 13-10-2018 IPR004087 K Homology domain GO:0003676 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 SUPERFAMILY SSF55666 449 547 2.24E-29 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 SUPERFAMILY SSF50249 606 691 9.77E-23 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 Gene3D G3DSA:2.40.50.140 621 693 5.1E-31 T 13-10-2018 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 Pfam PF00575 S1 RNA binding domain 618 689 7.0E-20 T 13-10-2018 IPR003029 S1 domain GO:0003676 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 Gene3D G3DSA:3.30.230.70 2 227 1.8E-80 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 Pfam PF03725 3' exoribonuclease family, domain 2 458 527 1.0E-6 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THITH_12885 2cb72de0a2b7657670b4153fe2a233d2 694 Pfam PF03725 3' exoribonuclease family, domain 2 145 208 3.2E-12 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THITH_04390 10c88fb371b41db85fcc75db50cec075 230 TIGRFAM TIGR01691 enolase-ppase: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 2 206 4.7E-75 T 13-10-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 THITH_04390 10c88fb371b41db85fcc75db50cec075 230 Gene3D G3DSA:3.40.50.1000 4 207 8.3E-71 T 13-10-2018 IPR023214 HAD superfamily THITH_04390 10c88fb371b41db85fcc75db50cec075 230 Gene3D G3DSA:1.10.720.60 16 98 8.3E-71 T 13-10-2018 THITH_04390 10c88fb371b41db85fcc75db50cec075 230 SUPERFAMILY SSF56784 2 222 1.31E-59 T 13-10-2018 IPR036412 HAD-like superfamily THITH_04390 10c88fb371b41db85fcc75db50cec075 230 Hamap MF_01681 Enolase-phosphatase E1 [mtnC]. 1 222 40.613 T 13-10-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 THITH_17100 f7ca407130cda2f8734ea639ccab0e32 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 205 229 9.6E-39 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THITH_17100 f7ca407130cda2f8734ea639ccab0e32 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 65 92 9.6E-39 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THITH_17100 f7ca407130cda2f8734ea639ccab0e32 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 180 204 9.6E-39 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THITH_17100 f7ca407130cda2f8734ea639ccab0e32 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 15 32 9.6E-39 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THITH_17100 f7ca407130cda2f8734ea639ccab0e32 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 245 262 9.6E-39 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THITH_17100 f7ca407130cda2f8734ea639ccab0e32 340 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 140 160 9.6E-39 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THITH_17100 f7ca407130cda2f8734ea639ccab0e32 340 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 13 165 5.9E-45 T 13-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THITH_17100 f7ca407130cda2f8734ea639ccab0e32 340 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 11 329 36.293 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THITH_17100 f7ca407130cda2f8734ea639ccab0e32 340 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 187 326 7.9E-49 T 13-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THITH_17100 f7ca407130cda2f8734ea639ccab0e32 340 Gene3D G3DSA:1.10.1040.10 196 339 6.5E-48 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THITH_17100 f7ca407130cda2f8734ea639ccab0e32 340 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 195 216 - T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THITH_17100 f7ca407130cda2f8734ea639ccab0e32 340 Gene3D G3DSA:3.40.50.720 2 194 7.4E-55 T 13-10-2018 THITH_17100 f7ca407130cda2f8734ea639ccab0e32 340 SUPERFAMILY SSF48179 187 338 3.23E-52 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THITH_17100 f7ca407130cda2f8734ea639ccab0e32 340 SUPERFAMILY SSF51735 12 187 1.97E-49 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_17100 f7ca407130cda2f8734ea639ccab0e32 340 PIRSF PIRSF000114 6 339 4.0E-92 T 13-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 THITH_02530 06959715ae683f11ffc18a63cc857253 176 Gene3D G3DSA:3.90.79.10 1 156 1.5E-44 T 13-10-2018 THITH_02530 06959715ae683f11ffc18a63cc857253 176 SUPERFAMILY SSF55811 6 153 4.06E-30 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 THITH_02530 06959715ae683f11ffc18a63cc857253 176 Pfam PF00293 NUDIX domain 7 146 1.1E-24 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 THITH_02530 06959715ae683f11ffc18a63cc857253 176 PRINTS PR00502 NUDIX hydrolase family signature 47 62 6.7E-7 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 THITH_02530 06959715ae683f11ffc18a63cc857253 176 PRINTS PR00502 NUDIX hydrolase family signature 33 47 6.7E-7 T 13-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 THITH_02530 06959715ae683f11ffc18a63cc857253 176 Hamap MF_00298 RNA pyrophosphohydrolase [rppH]. 1 156 36.583 T 13-10-2018 IPR022927 RNA pyrophosphohydrolase RppH THITH_02530 06959715ae683f11ffc18a63cc857253 176 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THITH_16765 f76e3e6e786d891d7969b421bd876d82 90 TIGRFAM TIGR00053 TIGR00053: addiction module toxin component, YafQ family 3 88 2.7E-27 T 13-10-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin THITH_16765 f76e3e6e786d891d7969b421bd876d82 90 Pfam PF15738 Bacterial toxin of type II toxin-antitoxin system, YafQ 5 89 5.7E-32 T 13-10-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin THITH_16765 f76e3e6e786d891d7969b421bd876d82 90 PIRSF PIRSF006156 1 90 4.5E-25 T 13-10-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin THITH_16765 f76e3e6e786d891d7969b421bd876d82 90 Gene3D G3DSA:3.30.2310.20 1 90 1.4E-31 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_16765 f76e3e6e786d891d7969b421bd876d82 90 SUPERFAMILY SSF143011 1 88 8.63E-26 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_16765 f76e3e6e786d891d7969b421bd876d82 90 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 7 88 1.6E-26 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THITH_00375 ee9494278d820c4cfba386b99f893397 144 Pfam PF00114 Pilin (bacterial filament) 40 144 7.7E-8 T 13-10-2018 IPR001082 Fimbrial protein pilin GO:0007155|GO:0009289 THITH_00375 ee9494278d820c4cfba386b99f893397 144 SUPERFAMILY SSF54523 11 141 2.09E-23 T 13-10-2018 THITH_00375 ee9494278d820c4cfba386b99f893397 144 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 31 8.1E-11 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_00375 ee9494278d820c4cfba386b99f893397 144 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_00375 ee9494278d820c4cfba386b99f893397 144 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 31 1.2E-10 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_00375 ee9494278d820c4cfba386b99f893397 144 Gene3D G3DSA:3.30.700.10 11 144 1.1E-32 T 13-10-2018 THITH_05055 e32ee5b4a214a6fb5d7860f8450345b4 498 Gene3D G3DSA:3.10.20.30 156 259 1.8E-21 T 13-10-2018 IPR012675 Beta-grasp domain superfamily THITH_05055 e32ee5b4a214a6fb5d7860f8450345b4 498 Gene3D G3DSA:2.40.30.10 265 363 1.4E-14 T 13-10-2018 THITH_05055 e32ee5b4a214a6fb5d7860f8450345b4 498 Gene3D G3DSA:3.40.50.80 364 492 3.3E-9 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain THITH_05055 e32ee5b4a214a6fb5d7860f8450345b4 498 SUPERFAMILY SSF54292 155 253 7.6E-24 T 13-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 THITH_05055 e32ee5b4a214a6fb5d7860f8450345b4 498 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 176 245 1.7E-11 T 13-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 THITH_05055 e32ee5b4a214a6fb5d7860f8450345b4 498 SUPERFAMILY SSF52343 353 490 2.62E-16 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain THITH_05055 e32ee5b4a214a6fb5d7860f8450345b4 498 PRINTS PR00410 Phenol hydroxylase reductase family signature 357 366 1.4E-8 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THITH_05055 e32ee5b4a214a6fb5d7860f8450345b4 498 PRINTS PR00410 Phenol hydroxylase reductase family signature 373 392 1.4E-8 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THITH_05055 e32ee5b4a214a6fb5d7860f8450345b4 498 PRINTS PR00410 Phenol hydroxylase reductase family signature 296 308 1.4E-8 T 13-10-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 THITH_05055 e32ee5b4a214a6fb5d7860f8450345b4 498 SUPERFAMILY SSF63380 266 363 2.87E-14 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel THITH_16050 519644f12c8dbe99752274ff9cb6a11e 272 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 226 248 - T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 THITH_16050 519644f12c8dbe99752274ff9cb6a11e 272 Gene3D G3DSA:3.40.50.720 6 167 2.6E-44 T 13-10-2018 THITH_16050 519644f12c8dbe99752274ff9cb6a11e 272 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 166 270 1.9E-30 T 13-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 THITH_16050 519644f12c8dbe99752274ff9cb6a11e 272 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 6 270 25.266 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 THITH_16050 519644f12c8dbe99752274ff9cb6a11e 272 SUPERFAMILY SSF51735 9 163 2.34E-33 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_16050 519644f12c8dbe99752274ff9cb6a11e 272 PIRSF PIRSF000193 6 272 8.2E-68 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 THITH_16050 519644f12c8dbe99752274ff9cb6a11e 272 Gene3D G3DSA:1.10.3730.10 168 272 3.1E-36 T 13-10-2018 THITH_16050 519644f12c8dbe99752274ff9cb6a11e 272 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 9 102 1.7E-15 T 13-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal THITH_16050 519644f12c8dbe99752274ff9cb6a11e 272 SUPERFAMILY SSF48179 166 271 1.87E-30 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THITH_16050 519644f12c8dbe99752274ff9cb6a11e 272 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 9 270 4.3E-77 T 13-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 THITH_12135 c98635d93620138e9ddd4ad795c814f9 226 SUPERFAMILY SSF54768 106 220 4.71E-25 T 13-10-2018 THITH_12135 c98635d93620138e9ddd4ad795c814f9 226 ProSitePatterns PS00517 Ribonuclease III family signature. 35 43 - T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 THITH_12135 c98635d93620138e9ddd4ad795c814f9 226 Hamap MF_00104 Ribonuclease 3 [rnc]. 6 217 28.471 T 13-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 THITH_12135 c98635d93620138e9ddd4ad795c814f9 226 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 18 220 1.8E-69 T 13-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 THITH_12135 c98635d93620138e9ddd4ad795c814f9 226 Gene3D G3DSA:3.30.160.20 151 225 3.6E-20 T 13-10-2018 THITH_12135 c98635d93620138e9ddd4ad795c814f9 226 Gene3D G3DSA:1.10.1520.10 6 144 5.9E-38 T 13-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 THITH_12135 c98635d93620138e9ddd4ad795c814f9 226 Pfam PF00035 Double-stranded RNA binding motif 153 220 4.8E-13 T 13-10-2018 IPR014720 Double-stranded RNA-binding domain THITH_12135 c98635d93620138e9ddd4ad795c814f9 226 SUPERFAMILY SSF69065 19 156 4.36E-42 T 13-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 THITH_12135 c98635d93620138e9ddd4ad795c814f9 226 SMART SM00358 153 221 7.3E-20 T 13-10-2018 IPR014720 Double-stranded RNA-binding domain THITH_12135 c98635d93620138e9ddd4ad795c814f9 226 SMART SM00535 18 146 2.5E-47 T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 THITH_12135 c98635d93620138e9ddd4ad795c814f9 226 Pfam PF14622 Ribonuclease-III-like 20 139 2.8E-33 T 13-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 THITH_05435 29c7bdb25e1433a68b7f81fe92242c5e 343 Gene3D G3DSA:3.40.50.150 66 243 5.8E-47 T 13-10-2018 THITH_05435 29c7bdb25e1433a68b7f81fe92242c5e 343 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 40 337 2.7E-120 T 13-10-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 THITH_05435 29c7bdb25e1433a68b7f81fe92242c5e 343 SUPERFAMILY SSF53335 58 326 4.11E-11 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_05435 29c7bdb25e1433a68b7f81fe92242c5e 343 PIRSF PIRSF018005 15 341 7.0E-115 T 13-10-2018 IPR017804 Methyltransferase EgtD-like GO:0008168 THITH_05435 29c7bdb25e1433a68b7f81fe92242c5e 343 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 40 339 1.3E-107 T 13-10-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent THITH_11465 0f12667aad6f0c0ac383f63b56ee6c22 168 Pfam PF02627 Carboxymuconolactone decarboxylase family 41 95 2.1E-5 T 13-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 THITH_11465 0f12667aad6f0c0ac383f63b56ee6c22 168 Gene3D G3DSA:1.20.1290.10 5 168 1.3E-30 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 THITH_11465 0f12667aad6f0c0ac383f63b56ee6c22 168 SUPERFAMILY SSF69118 8 166 1.08E-29 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 THITH_05805 bb64a3c63cc0a3e9b2d4c14193fc346e 358 Gene3D G3DSA:3.40.50.2000 6 349 8.2E-114 T 13-10-2018 THITH_05805 bb64a3c63cc0a3e9b2d4c14193fc346e 358 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 23 352 6.2E-103 T 13-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 THITH_05805 bb64a3c63cc0a3e9b2d4c14193fc346e 358 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 2 326 7.7E-87 T 13-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 THITH_05805 bb64a3c63cc0a3e9b2d4c14193fc346e 358 SUPERFAMILY SSF53756 2 352 4.65E-99 T 13-10-2018 THITH_05805 bb64a3c63cc0a3e9b2d4c14193fc346e 358 Gene3D G3DSA:3.40.50.2000 185 339 8.2E-114 T 13-10-2018 THITH_13415 cad5ce185a7e3907f9a30c71643a345e 90 SMART SM00411 1 90 2.6E-43 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THITH_13415 cad5ce185a7e3907f9a30c71643a345e 90 SUPERFAMILY SSF47729 1 90 3.24E-33 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 THITH_13415 cad5ce185a7e3907f9a30c71643a345e 90 Gene3D G3DSA:4.10.520.10 1 90 3.0E-36 T 13-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 THITH_13415 cad5ce185a7e3907f9a30c71643a345e 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 13-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 THITH_13415 cad5ce185a7e3907f9a30c71643a345e 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 6.1E-19 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THITH_13415 cad5ce185a7e3907f9a30c71643a345e 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 6.1E-19 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THITH_13415 cad5ce185a7e3907f9a30c71643a345e 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 6.1E-19 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THITH_13415 cad5ce185a7e3907f9a30c71643a345e 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 3.2E-34 T 13-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 THITH_02675 aca04e7b14c1f3fe3b9341f7d486f38f 86 Pfam PF00886 Ribosomal protein S16 8 68 6.7E-21 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_02675 aca04e7b14c1f3fe3b9341f7d486f38f 86 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 1 78 22.664 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_02675 aca04e7b14c1f3fe3b9341f7d486f38f 86 SUPERFAMILY SSF54565 1 77 4.45E-26 T 13-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_02675 aca04e7b14c1f3fe3b9341f7d486f38f 86 TIGRFAM TIGR00002 S16: ribosomal protein bS16 2 78 6.9E-26 T 13-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_02675 aca04e7b14c1f3fe3b9341f7d486f38f 86 Gene3D G3DSA:3.30.1320.10 1 82 2.8E-28 T 13-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_02675 aca04e7b14c1f3fe3b9341f7d486f38f 86 ProSitePatterns PS00732 Ribosomal protein S16 signature. 2 11 - T 13-10-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_03335 834687f786cc9fddf4a15e704c5915fb 621 Pfam PF05199 GMC oxidoreductase 466 596 1.8E-15 T 13-10-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 THITH_03335 834687f786cc9fddf4a15e704c5915fb 621 Gene3D G3DSA:3.50.50.60 8 182 2.1E-18 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_03335 834687f786cc9fddf4a15e704c5915fb 621 Pfam PF13450 NAD(P)-binding Rossmann-like domain 19 47 3.1E-5 T 13-10-2018 THITH_03335 834687f786cc9fddf4a15e704c5915fb 621 Gene3D G3DSA:3.50.50.60 538 613 2.8E-9 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_03335 834687f786cc9fddf4a15e704c5915fb 621 SUPERFAMILY SSF51905 11 608 1.37E-48 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_02850 5dfc2eec6848a2b0e5d837e890181341 447 Pfam PF07670 Nucleoside recognition 315 414 2.9E-6 T 13-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 THITH_02850 5dfc2eec6848a2b0e5d837e890181341 447 Pfam PF07670 Nucleoside recognition 51 156 2.3E-9 T 13-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 THITH_02850 5dfc2eec6848a2b0e5d837e890181341 447 PIRSF PIRSF036542 254 447 1.8E-52 T 13-10-2018 IPR011415 Predicted bifunctional spore maturation protein, fused SpmA/SpmB THITH_02850 5dfc2eec6848a2b0e5d837e890181341 447 PIRSF PIRSF036542 1 205 1.5E-58 T 13-10-2018 IPR011415 Predicted bifunctional spore maturation protein, fused SpmA/SpmB THITH_10955 a5c72f3f040107a18c03fd6bc41e36db 449 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 294 4.7E-55 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THITH_10955 a5c72f3f040107a18c03fd6bc41e36db 449 SUPERFAMILY SSF51905 1 350 1.56E-40 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_10955 a5c72f3f040107a18c03fd6bc41e36db 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 256 1.9E-23 T 13-10-2018 THITH_10955 a5c72f3f040107a18c03fd6bc41e36db 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 1.9E-23 T 13-10-2018 THITH_10955 a5c72f3f040107a18c03fd6bc41e36db 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 1.9E-23 T 13-10-2018 THITH_10955 a5c72f3f040107a18c03fd6bc41e36db 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 1.9E-23 T 13-10-2018 THITH_10955 a5c72f3f040107a18c03fd6bc41e36db 449 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.9E-23 T 13-10-2018 THITH_10955 a5c72f3f040107a18c03fd6bc41e36db 449 Gene3D G3DSA:3.50.50.60 117 445 5.5E-162 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_10955 a5c72f3f040107a18c03fd6bc41e36db 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 282 289 5.5E-14 T 13-10-2018 THITH_10955 a5c72f3f040107a18c03fd6bc41e36db 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 5.5E-14 T 13-10-2018 THITH_10955 a5c72f3f040107a18c03fd6bc41e36db 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 5.5E-14 T 13-10-2018 THITH_10955 a5c72f3f040107a18c03fd6bc41e36db 449 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 241 255 5.5E-14 T 13-10-2018 THITH_10955 a5c72f3f040107a18c03fd6bc41e36db 449 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 335 436 1.5E-17 T 13-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 THITH_10955 a5c72f3f040107a18c03fd6bc41e36db 449 Gene3D G3DSA:3.50.50.60 5 345 5.5E-162 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_10955 a5c72f3f040107a18c03fd6bc41e36db 449 SUPERFAMILY SSF55424 328 447 3.09E-32 T 13-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 THITH_01100 0f00e16400cb3514f4f178895e223c54 956 SMART SM00490 464 548 2.1E-12 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_01100 0f00e16400cb3514f4f178895e223c54 956 Gene3D G3DSA:3.40.50.10810 101 386 9.8E-57 T 13-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily THITH_01100 0f00e16400cb3514f4f178895e223c54 956 SUPERFAMILY SSF52540 226 602 1.17E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01100 0f00e16400cb3514f4f178895e223c54 956 Pfam PF00271 Helicase conserved C-terminal domain 442 548 3.4E-11 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_01100 0f00e16400cb3514f4f178895e223c54 956 SMART SM00487 100 302 7.0E-11 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_01100 0f00e16400cb3514f4f178895e223c54 956 Pfam PF00176 SNF2 family N-terminal domain 124 289 6.6E-10 T 13-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 THITH_01100 0f00e16400cb3514f4f178895e223c54 956 SUPERFAMILY SSF52540 103 295 1.51E-30 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01100 0f00e16400cb3514f4f178895e223c54 956 Gene3D G3DSA:3.40.50.300 416 589 7.4E-27 T 13-10-2018 THITH_08810 cc75788df37b0b95c6451dacdb88553c 459 Pfam PF10415 Fumarase C C-terminus 404 456 1.6E-14 T 13-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THITH_08810 cc75788df37b0b95c6451dacdb88553c 459 PRINTS PR00145 Argininosuccinate lyase family signature 129 151 3.8E-6 T 13-10-2018 THITH_08810 cc75788df37b0b95c6451dacdb88553c 459 PRINTS PR00145 Argininosuccinate lyase family signature 313 329 3.8E-6 T 13-10-2018 THITH_08810 cc75788df37b0b95c6451dacdb88553c 459 PRINTS PR00145 Argininosuccinate lyase family signature 171 191 3.8E-6 T 13-10-2018 THITH_08810 cc75788df37b0b95c6451dacdb88553c 459 PRINTS PR00149 Fumarate lyase superfamily signature 176 194 7.3E-30 T 13-10-2018 IPR000362 Fumarate lyase family THITH_08810 cc75788df37b0b95c6451dacdb88553c 459 PRINTS PR00149 Fumarate lyase superfamily signature 313 329 7.3E-30 T 13-10-2018 IPR000362 Fumarate lyase family THITH_08810 cc75788df37b0b95c6451dacdb88553c 459 PRINTS PR00149 Fumarate lyase superfamily signature 267 294 7.3E-30 T 13-10-2018 IPR000362 Fumarate lyase family THITH_08810 cc75788df37b0b95c6451dacdb88553c 459 PRINTS PR00149 Fumarate lyase superfamily signature 130 148 7.3E-30 T 13-10-2018 IPR000362 Fumarate lyase family THITH_08810 cc75788df37b0b95c6451dacdb88553c 459 Gene3D G3DSA:1.10.40.30 404 455 1.1E-16 T 13-10-2018 THITH_08810 cc75788df37b0b95c6451dacdb88553c 459 Hamap MF_00743 Fumarate hydratase class II [fumC]. 7 458 73.963 T 13-10-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 THITH_08810 cc75788df37b0b95c6451dacdb88553c 459 Gene3D G3DSA:1.20.200.10 135 400 5.3E-99 T 13-10-2018 THITH_08810 cc75788df37b0b95c6451dacdb88553c 459 Pfam PF00206 Lyase 15 338 3.4E-94 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal THITH_08810 cc75788df37b0b95c6451dacdb88553c 459 ProSitePatterns PS00163 Fumarate lyases signature. 313 322 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 THITH_08810 cc75788df37b0b95c6451dacdb88553c 459 SUPERFAMILY SSF48557 7 453 5.81E-134 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 THITH_08810 cc75788df37b0b95c6451dacdb88553c 459 Gene3D G3DSA:1.10.275.10 8 134 7.4E-50 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal THITH_13465 09e0b9ba98fae539f8f683031af0b316 601 Gene3D G3DSA:3.30.1370.100 457 552 5.1E-57 T 13-10-2018 THITH_13465 09e0b9ba98fae539f8f683031af0b316 601 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 212 328 1.5E-36 T 13-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 THITH_13465 09e0b9ba98fae539f8f683031af0b316 601 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 1 597 28.32 T 13-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 THITH_13465 09e0b9ba98fae539f8f683031af0b316 601 Gene3D G3DSA:2.30.42.20 416 594 5.1E-57 T 13-10-2018 THITH_13465 09e0b9ba98fae539f8f683031af0b316 601 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 2 309 1.1E-95 T 13-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 THITH_13465 09e0b9ba98fae539f8f683031af0b316 601 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 24 82 9.7E-9 T 13-10-2018 THITH_13465 09e0b9ba98fae539f8f683031af0b316 601 SMART SM01340 211 329 3.5E-56 T 13-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 THITH_13465 09e0b9ba98fae539f8f683031af0b316 601 Pfam PF08676 MutL C terminal dimerisation domain 410 557 9.3E-46 T 13-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 THITH_13465 09e0b9ba98fae539f8f683031af0b316 601 Gene3D G3DSA:3.30.565.10 1 210 2.2E-66 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_13465 09e0b9ba98fae539f8f683031af0b316 601 SUPERFAMILY SSF55874 2 200 4.45E-52 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_13465 09e0b9ba98fae539f8f683031af0b316 601 SMART SM00853 414 557 2.6E-46 T 13-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 THITH_13465 09e0b9ba98fae539f8f683031af0b316 601 SUPERFAMILY SSF118116 410 599 2.88E-55 T 13-10-2018 IPR037198 MutL, C-terminal domain superfamily THITH_13465 09e0b9ba98fae539f8f683031af0b316 601 SUPERFAMILY SSF54211 191 329 5.31E-35 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_13465 09e0b9ba98fae539f8f683031af0b316 601 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 93 99 - T 13-10-2018 IPR014762 DNA mismatch repair, conserved site THITH_13465 09e0b9ba98fae539f8f683031af0b316 601 Gene3D G3DSA:3.30.230.10 216 328 2.1E-35 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THITH_13360 6d0812ed27bccb40d4329fcc5bf86f14 318 SMART SM00382 29 172 3.5E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_13360 6d0812ed27bccb40d4329fcc5bf86f14 318 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 281 298 4.0E-15 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_13360 6d0812ed27bccb40d4329fcc5bf86f14 318 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 298 318 4.0E-15 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_13360 6d0812ed27bccb40d4329fcc5bf86f14 318 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 95 110 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THITH_13360 6d0812ed27bccb40d4329fcc5bf86f14 318 Gene3D G3DSA:1.10.8.60 180 258 8.3E-23 T 13-10-2018 THITH_13360 6d0812ed27bccb40d4329fcc5bf86f14 318 Pfam PF00158 Sigma-54 interaction domain 9 175 2.9E-67 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THITH_13360 6d0812ed27bccb40d4329fcc5bf86f14 318 Gene3D G3DSA:1.10.10.60 262 318 1.9E-16 T 13-10-2018 THITH_13360 6d0812ed27bccb40d4329fcc5bf86f14 318 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 222 231 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site THITH_13360 6d0812ed27bccb40d4329fcc5bf86f14 318 SUPERFAMILY SSF46689 222 317 1.15E-16 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_13360 6d0812ed27bccb40d4329fcc5bf86f14 318 Gene3D G3DSA:3.40.50.300 3 179 4.3E-61 T 13-10-2018 THITH_13360 6d0812ed27bccb40d4329fcc5bf86f14 318 Pfam PF02954 Bacterial regulatory protein, Fis family 275 315 1.0E-16 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_13360 6d0812ed27bccb40d4329fcc5bf86f14 318 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 33 46 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THITH_13360 6d0812ed27bccb40d4329fcc5bf86f14 318 SUPERFAMILY SSF52540 9 251 6.98E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_15820 da12ad7f5d43311ffa638e4db61eb59f 101 Gene3D G3DSA:3.40.30.10 4 101 1.0E-28 T 13-10-2018 THITH_15820 da12ad7f5d43311ffa638e4db61eb59f 101 SUPERFAMILY SSF52833 4 100 5.48E-24 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_12255 f76229114cd21fb6204c063c26d3d285 650 Gene3D G3DSA:3.40.50.300 448 639 1.8E-32 T 13-10-2018 THITH_12255 f76229114cd21fb6204c063c26d3d285 650 Gene3D G3DSA:3.40.50.300 22 254 4.0E-43 T 13-10-2018 THITH_12255 f76229114cd21fb6204c063c26d3d285 650 SUPERFAMILY SSF52540 19 235 1.17E-21 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_12255 f76229114cd21fb6204c063c26d3d285 650 SMART SM00491 478 609 2.8E-35 T 13-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 THITH_12255 f76229114cd21fb6204c063c26d3d285 650 Pfam PF13307 Helicase C-terminal domain 464 620 5.1E-34 T 13-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 THITH_12255 f76229114cd21fb6204c063c26d3d285 650 SUPERFAMILY SSF52540 46 599 6.28E-10 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_12255 f76229114cd21fb6204c063c26d3d285 650 Pfam PF00270 DEAD/DEAH box helicase 27 233 9.9E-7 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THITH_06470 1ef3aa46a519f7b7a9910337812366b7 277 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 236 265 3.7E-8 T 13-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain THITH_06470 1ef3aa46a519f7b7a9910337812366b7 277 Gene3D G3DSA:2.40.30.10 3 101 7.0E-15 T 13-10-2018 THITH_06470 1ef3aa46a519f7b7a9910337812366b7 277 Gene3D G3DSA:3.40.50.80 103 232 5.3E-21 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain THITH_06470 1ef3aa46a519f7b7a9910337812366b7 277 PRINTS PR00406 Cytochrome B5 reductase signature 152 163 1.0E-6 T 13-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 THITH_06470 1ef3aa46a519f7b7a9910337812366b7 277 PRINTS PR00406 Cytochrome B5 reductase signature 204 212 1.0E-6 T 13-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 THITH_06470 1ef3aa46a519f7b7a9910337812366b7 277 PRINTS PR00406 Cytochrome B5 reductase signature 114 133 1.0E-6 T 13-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 THITH_06470 1ef3aa46a519f7b7a9910337812366b7 277 PRINTS PR00406 Cytochrome B5 reductase signature 90 104 1.0E-6 T 13-10-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 THITH_06470 1ef3aa46a519f7b7a9910337812366b7 277 PIRSF PIRSF006816 4 270 6.7E-67 T 13-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 THITH_06470 1ef3aa46a519f7b7a9910337812366b7 277 SUPERFAMILY SSF63380 7 103 1.51E-19 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel THITH_06470 1ef3aa46a519f7b7a9910337812366b7 277 Pfam PF00970 Oxidoreductase FAD-binding domain 12 101 2.3E-4 T 13-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 THITH_06470 1ef3aa46a519f7b7a9910337812366b7 277 Pfam PF00175 Oxidoreductase NAD-binding domain 115 216 4.8E-12 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THITH_06470 1ef3aa46a519f7b7a9910337812366b7 277 SUPERFAMILY SSF52343 98 266 8.64E-28 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain THITH_07140 b55ac43e927f75706c32e3d43efc9425 262 PIRSF PIRSF006648 1 261 5.9E-28 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 THITH_07140 b55ac43e927f75706c32e3d43efc9425 262 TIGRFAM TIGR01291 nodJ: ABC-2 type transporter, NodJ family 14 261 1.1E-70 T 13-10-2018 IPR005981 ABC-2 type transporter, NodJ GO:0005215|GO:0009877|GO:0015772|GO:0016020 THITH_07140 b55ac43e927f75706c32e3d43efc9425 262 Pfam PF01061 ABC-2 type transporter 16 226 6.6E-25 T 13-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 THITH_07140 b55ac43e927f75706c32e3d43efc9425 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 204 223 7.0E-38 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 THITH_07140 b55ac43e927f75706c32e3d43efc9425 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 184 203 7.0E-38 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 THITH_07140 b55ac43e927f75706c32e3d43efc9425 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 35 56 7.0E-38 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 THITH_07140 b55ac43e927f75706c32e3d43efc9425 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 65 87 7.0E-38 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 THITH_07140 b55ac43e927f75706c32e3d43efc9425 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 147 171 7.0E-38 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 THITH_07140 b55ac43e927f75706c32e3d43efc9425 262 PRINTS PR00164 ABC-2 type transport system membrane protein signature 110 135 7.0E-38 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 THITH_05680 82b185255cb831ce2c285460221f83e0 306 Gene3D G3DSA:3.60.15.10 11 281 4.6E-80 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_05680 82b185255cb831ce2c285460221f83e0 306 SUPERFAMILY SSF56281 13 301 4.57E-74 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_05680 82b185255cb831ce2c285460221f83e0 306 SMART SM01027 88 220 4.1E-56 T 13-10-2018 IPR022712 Beta-Casp domain THITH_05680 82b185255cb831ce2c285460221f83e0 306 Pfam PF10996 Beta-Casp domain 88 220 4.8E-29 T 13-10-2018 IPR022712 Beta-Casp domain THITH_05680 82b185255cb831ce2c285460221f83e0 306 Gene3D G3DSA:3.40.50.10890 56 249 4.6E-80 T 13-10-2018 THITH_05680 82b185255cb831ce2c285460221f83e0 306 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 237 290 8.3E-12 T 13-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain THITH_13150 90f7017ce23dc11bc871102245b7667b 141 Pfam PF01475 Ferric uptake regulator family 8 127 3.8E-45 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 THITH_13150 90f7017ce23dc11bc871102245b7667b 141 SUPERFAMILY SSF46785 4 131 2.06E-42 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_13150 90f7017ce23dc11bc871102245b7667b 141 Gene3D G3DSA:3.30.1490.190 84 139 3.4E-18 T 13-10-2018 THITH_13150 90f7017ce23dc11bc871102245b7667b 141 Gene3D G3DSA:1.10.10.10 1 81 7.2E-34 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_02900 e709d94975264421a2e642b31ce88622 349 Gene3D G3DSA:1.10.10.10 258 335 5.5E-29 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_02900 e709d94975264421a2e642b31ce88622 349 SUPERFAMILY SSF52540 21 252 4.12E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_02900 e709d94975264421a2e642b31ce88622 349 Gene3D G3DSA:3.40.50.300 19 182 3.1E-34 T 13-10-2018 THITH_02900 e709d94975264421a2e642b31ce88622 349 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 8.7E-30 T 13-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 THITH_02900 e709d94975264421a2e642b31ce88622 349 SMART SM00382 52 183 5.1E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_02900 e709d94975264421a2e642b31ce88622 349 SUPERFAMILY SSF46785 258 329 3.33E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_02900 e709d94975264421a2e642b31ce88622 349 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 5 236 1.2E-110 T 13-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 THITH_02900 e709d94975264421a2e642b31ce88622 349 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 25 327 1.1E-136 T 13-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 THITH_02900 e709d94975264421a2e642b31ce88622 349 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 262 328 5.0E-22 T 13-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 THITH_02900 e709d94975264421a2e642b31ce88622 349 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 349 164.578 T 13-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 THITH_02900 e709d94975264421a2e642b31ce88622 349 Gene3D G3DSA:1.10.8.60 183 256 2.5E-27 T 13-10-2018 THITH_06515 728fba7c995c3dd31c54d7537a9c3da3 353 Pfam PF00534 Glycosyl transferases group 1 190 320 9.0E-17 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 THITH_06515 728fba7c995c3dd31c54d7537a9c3da3 353 Gene3D G3DSA:3.40.50.2000 178 333 2.1E-21 T 13-10-2018 THITH_06515 728fba7c995c3dd31c54d7537a9c3da3 353 SUPERFAMILY SSF53756 24 319 8.37E-27 T 13-10-2018 THITH_16040 6cb642b369e41fea730eebfb334bafbe 344 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 193 207 - T 13-10-2018 IPR001482 Type II/IV secretion system protein THITH_16040 6cb642b369e41fea730eebfb334bafbe 344 SUPERFAMILY SSF52540 4 336 6.53E-74 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16040 6cb642b369e41fea730eebfb334bafbe 344 Gene3D G3DSA:3.30.450.90 1 100 5.5E-36 T 13-10-2018 THITH_16040 6cb642b369e41fea730eebfb334bafbe 344 Pfam PF00437 Type II/IV secretion system protein 11 268 1.4E-45 T 13-10-2018 IPR001482 Type II/IV secretion system protein THITH_16040 6cb642b369e41fea730eebfb334bafbe 344 Gene3D G3DSA:3.40.50.300 101 344 1.7E-103 T 13-10-2018 THITH_16040 6cb642b369e41fea730eebfb334bafbe 344 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 3 340 2.8E-150 T 13-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 THITH_00955 7e76cb2e70fad0aadd92af731d4beff8 945 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 35 646 4.7E-206 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_00955 7e76cb2e70fad0aadd92af731d4beff8 945 Gene3D G3DSA:1.10.730.20 646 937 2.4E-88 T 13-10-2018 THITH_00955 7e76cb2e70fad0aadd92af731d4beff8 945 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 9 936 20.886 T 13-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 THITH_00955 7e76cb2e70fad0aadd92af731d4beff8 945 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 567 576 4.1E-30 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THITH_00955 7e76cb2e70fad0aadd92af731d4beff8 945 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 533 546 4.1E-30 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THITH_00955 7e76cb2e70fad0aadd92af731d4beff8 945 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 408 423 4.1E-30 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THITH_00955 7e76cb2e70fad0aadd92af731d4beff8 945 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 58 69 4.1E-30 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THITH_00955 7e76cb2e70fad0aadd92af731d4beff8 945 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 246 269 4.1E-30 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THITH_00955 7e76cb2e70fad0aadd92af731d4beff8 945 Gene3D G3DSA:3.90.740.10 202 415 9.7E-233 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 THITH_00955 7e76cb2e70fad0aadd92af731d4beff8 945 Pfam PF06827 Zinc finger found in FPG and IleRS 907 933 1.2E-6 T 13-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 THITH_00955 7e76cb2e70fad0aadd92af731d4beff8 945 SUPERFAMILY SSF52374 11 654 6.17E-137 T 13-10-2018 THITH_00955 7e76cb2e70fad0aadd92af731d4beff8 945 Pfam PF08264 Anticodon-binding domain of tRNA 691 845 1.5E-26 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 THITH_00955 7e76cb2e70fad0aadd92af731d4beff8 945 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 65 76 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_00955 7e76cb2e70fad0aadd92af731d4beff8 945 Gene3D G3DSA:3.40.50.620 32 635 9.7E-233 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_00955 7e76cb2e70fad0aadd92af731d4beff8 945 SUPERFAMILY SSF50677 211 410 6.49E-53 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 THITH_00955 7e76cb2e70fad0aadd92af731d4beff8 945 SUPERFAMILY SSF47323 658 936 2.62E-74 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_00955 7e76cb2e70fad0aadd92af731d4beff8 945 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 22 848 3.5E-268 T 13-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 THITH_16535 108af30ad6ec26c23d8ef84fd77a1e27 250 Gene3D G3DSA:3.40.50.1820 3 249 2.4E-40 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_16535 108af30ad6ec26c23d8ef84fd77a1e27 250 SUPERFAMILY SSF53474 5 248 3.81E-34 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_16535 108af30ad6ec26c23d8ef84fd77a1e27 250 Pfam PF12697 Alpha/beta hydrolase family 11 243 9.6E-16 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_08915 47d2f717eb5fe559bbc11e65d2627ad5 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 217 7.3E-21 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THITH_08915 47d2f717eb5fe559bbc11e65d2627ad5 222 SUPERFAMILY SSF46894 118 218 2.21E-24 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THITH_08915 47d2f717eb5fe559bbc11e65d2627ad5 222 Pfam PF00072 Response regulator receiver domain 4 112 2.1E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_08915 47d2f717eb5fe559bbc11e65d2627ad5 222 SMART SM00862 146 217 1.5E-21 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THITH_08915 47d2f717eb5fe559bbc11e65d2627ad5 222 SUPERFAMILY SSF52172 2 118 3.7E-36 T 13-10-2018 IPR011006 CheY-like superfamily THITH_08915 47d2f717eb5fe559bbc11e65d2627ad5 222 Gene3D G3DSA:3.40.50.2300 1 122 6.4E-39 T 13-10-2018 THITH_08915 47d2f717eb5fe559bbc11e65d2627ad5 222 SMART SM00448 1 112 1.6E-34 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_08915 47d2f717eb5fe559bbc11e65d2627ad5 222 Gene3D G3DSA:1.10.10.10 123 221 4.2E-28 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_11365 6a80811bbafa6d201901d7f3b57ae1f5 168 PIRSF PIRSF000194 6 168 2.6E-57 T 13-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 THITH_11365 6a80811bbafa6d201901d7f3b57ae1f5 168 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 22 44 - T 13-10-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 THITH_11365 6a80811bbafa6d201901d7f3b57ae1f5 168 Gene3D G3DSA:3.40.430.10 10 168 1.3E-54 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 THITH_11365 6a80811bbafa6d201901d7f3b57ae1f5 168 SUPERFAMILY SSF53597 9 167 3.27E-52 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 THITH_11365 6a80811bbafa6d201901d7f3b57ae1f5 168 PRINTS PR00070 Dihydrofolate reductase signature 22 32 1.1E-14 T 13-10-2018 THITH_11365 6a80811bbafa6d201901d7f3b57ae1f5 168 PRINTS PR00070 Dihydrofolate reductase signature 49 60 1.1E-14 T 13-10-2018 THITH_11365 6a80811bbafa6d201901d7f3b57ae1f5 168 PRINTS PR00070 Dihydrofolate reductase signature 36 44 1.1E-14 T 13-10-2018 THITH_11365 6a80811bbafa6d201901d7f3b57ae1f5 168 PRINTS PR00070 Dihydrofolate reductase signature 99 113 1.1E-14 T 13-10-2018 THITH_11365 6a80811bbafa6d201901d7f3b57ae1f5 168 Pfam PF00186 Dihydrofolate reductase 11 166 5.7E-53 T 13-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 THITH_14065 1b017a08ecb823559ccf41923020fb3e 548 Gene3D G3DSA:3.50.50.60 18 386 3.0E-97 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_14065 1b017a08ecb823559ccf41923020fb3e 548 SUPERFAMILY SSF51905 17 313 5.44E-28 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_14065 1b017a08ecb823559ccf41923020fb3e 548 Gene3D G3DSA:3.30.9.10 95 338 3.0E-97 T 13-10-2018 THITH_14065 1b017a08ecb823559ccf41923020fb3e 548 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 46 58 1.9E-9 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 THITH_14065 1b017a08ecb823559ccf41923020fb3e 548 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 367 379 1.9E-9 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 THITH_14065 1b017a08ecb823559ccf41923020fb3e 548 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 17 29 1.9E-9 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 THITH_14065 1b017a08ecb823559ccf41923020fb3e 548 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 331 337 1.9E-9 T 13-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 THITH_14065 1b017a08ecb823559ccf41923020fb3e 548 Gene3D G3DSA:1.10.8.870 416 539 4.4E-11 T 13-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 THITH_14065 1b017a08ecb823559ccf41923020fb3e 548 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 431 516 2.2E-9 T 13-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 THITH_14065 1b017a08ecb823559ccf41923020fb3e 548 Pfam PF01266 FAD dependent oxidoreductase 18 341 2.6E-35 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THITH_01765 f3911374b9ed7116620d6c9104c84961 169 SUPERFAMILY SSF143744 34 161 1.24E-25 T 13-10-2018 IPR038084 GlcG-like domain superfamily THITH_01765 f3911374b9ed7116620d6c9104c84961 169 Pfam PF03928 Haem-degrading 38 158 5.0E-20 T 13-10-2018 IPR005624 Haem-degrading THITH_01765 f3911374b9ed7116620d6c9104c84961 169 Gene3D G3DSA:3.30.450.150 38 162 1.6E-31 T 13-10-2018 IPR038084 GlcG-like domain superfamily THITH_16690 c85ba1c51bf5936a7e1acd395d4bb81a 118 Gene3D G3DSA:3.30.70.1060 1 115 1.9E-36 T 13-10-2018 THITH_16690 c85ba1c51bf5936a7e1acd395d4bb81a 118 Pfam PF03795 YCII-related domain 6 111 2.8E-19 T 13-10-2018 IPR005545 YCII-related THITH_16690 c85ba1c51bf5936a7e1acd395d4bb81a 118 SUPERFAMILY SSF54909 1 113 1.18E-31 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel THITH_15590 21e1ee5d857a6e53ef76db0fb9fd7f7f 390 Gene3D G3DSA:3.10.350.10 77 125 1.3E-14 T 13-10-2018 IPR036779 LysM domain superfamily THITH_15590 21e1ee5d857a6e53ef76db0fb9fd7f7f 390 Pfam PF01476 LysM domain 79 125 1.8E-12 T 13-10-2018 IPR018392 LysM domain THITH_15590 21e1ee5d857a6e53ef76db0fb9fd7f7f 390 SMART SM00257 78 126 3.9E-5 T 13-10-2018 IPR018392 LysM domain THITH_15590 21e1ee5d857a6e53ef76db0fb9fd7f7f 390 SUPERFAMILY SSF54106 77 126 5.62E-8 T 13-10-2018 THITH_14545 54c6ab3e0c74964aad624006a9c5113e 208 Gene3D G3DSA:3.40.30.10 11 201 5.7E-69 T 13-10-2018 THITH_14545 54c6ab3e0c74964aad624006a9c5113e 208 SUPERFAMILY SSF47616 82 206 6.54E-19 T 13-10-2018 IPR036282 Glutathione S-transferase, C-terminal domain superfamily THITH_14545 54c6ab3e0c74964aad624006a9c5113e 208 Pfam PF13417 Glutathione S-transferase, N-terminal domain 13 87 1.3E-15 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THITH_14545 54c6ab3e0c74964aad624006a9c5113e 208 Gene3D G3DSA:1.20.1050.10 89 192 5.7E-69 T 13-10-2018 THITH_14545 54c6ab3e0c74964aad624006a9c5113e 208 SUPERFAMILY SSF52833 11 110 1.33E-22 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_00640 e6de1490758298360fd80514945188da 173 Gene3D G3DSA:1.10.287.950 42 164 7.2E-6 T 13-10-2018 THITH_00640 e6de1490758298360fd80514945188da 173 SUPERFAMILY SSF58104 75 157 2.35E-5 T 13-10-2018 THITH_04775 a96758c7202717453db4e3c1b59371b5 243 SMART SM00448 7 117 1.7E-40 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_04775 a96758c7202717453db4e3c1b59371b5 243 Gene3D G3DSA:3.40.50.2300 1 133 7.9E-37 T 13-10-2018 THITH_04775 a96758c7202717453db4e3c1b59371b5 243 SMART SM00862 158 234 1.5E-23 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THITH_04775 a96758c7202717453db4e3c1b59371b5 243 SUPERFAMILY SSF52172 4 128 1.22E-41 T 13-10-2018 IPR011006 CheY-like superfamily THITH_04775 a96758c7202717453db4e3c1b59371b5 243 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 234 5.4E-24 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THITH_04775 a96758c7202717453db4e3c1b59371b5 243 SUPERFAMILY SSF46894 136 235 1.62E-28 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THITH_04775 a96758c7202717453db4e3c1b59371b5 243 Gene3D G3DSA:1.10.10.10 134 241 5.1E-37 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_04775 a96758c7202717453db4e3c1b59371b5 243 Pfam PF00072 Response regulator receiver domain 9 118 7.9E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_17020 8d8c5ffaaf6437932dcbef508ce24611 140 Gene3D G3DSA:2.60.15.10 3 91 3.9E-30 T 13-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17020 8d8c5ffaaf6437932dcbef508ce24611 140 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 10 86 4.0E-22 T 13-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17020 8d8c5ffaaf6437932dcbef508ce24611 140 SUPERFAMILY SSF46604 89 137 1.26E-12 T 13-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17020 8d8c5ffaaf6437932dcbef508ce24611 140 Gene3D G3DSA:1.20.5.440 92 134 3.1E-14 T 13-10-2018 THITH_17020 8d8c5ffaaf6437932dcbef508ce24611 140 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 90 134 5.5E-10 T 13-10-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain THITH_17020 8d8c5ffaaf6437932dcbef508ce24611 140 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 133 3.5E-41 T 13-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17020 8d8c5ffaaf6437932dcbef508ce24611 140 SUPERFAMILY SSF51344 3 87 2.22E-22 T 13-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17020 8d8c5ffaaf6437932dcbef508ce24611 140 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 3 132 20.844 T 13-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17020 8d8c5ffaaf6437932dcbef508ce24611 140 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 5 85 9.1E-28 T 13-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_07990 370157c4091b5291f76c4e0ee3d7aaf7 86 SUPERFAMILY SSF47781 22 84 5.0E-26 T 13-10-2018 IPR010994 RuvA domain 2-like THITH_07990 370157c4091b5291f76c4e0ee3d7aaf7 86 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 25 84 6.1E-22 T 13-10-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain THITH_07990 370157c4091b5291f76c4e0ee3d7aaf7 86 SMART SM00278 63 82 3.0 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THITH_07990 370157c4091b5291f76c4e0ee3d7aaf7 86 SMART SM00278 33 52 3.3 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THITH_07990 370157c4091b5291f76c4e0ee3d7aaf7 86 Pfam PF12836 Helix-hairpin-helix motif 23 83 3.0E-22 T 13-10-2018 THITH_07990 370157c4091b5291f76c4e0ee3d7aaf7 86 Gene3D G3DSA:1.10.150.280 23 85 2.0E-21 T 13-10-2018 THITH_01850 c0ba584b70e611f40197ef4e417dde78 768 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 33 128 9.7E-11 T 13-10-2018 THITH_01850 c0ba584b70e611f40197ef4e417dde78 768 Gene3D G3DSA:3.30.565.10 1 203 2.7E-31 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_01850 c0ba584b70e611f40197ef4e417dde78 768 SUPERFAMILY SSF55874 5 188 1.57E-21 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_06775 ba8c97a9ef085e1f70ef78020cb1f49f 152 PRINTS PR00446 Hydrogen uptake protein signature 12 23 3.0E-11 T 13-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THITH_06775 ba8c97a9ef085e1f70ef78020cb1f49f 152 PRINTS PR00446 Hydrogen uptake protein signature 53 63 3.0E-11 T 13-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THITH_06775 ba8c97a9ef085e1f70ef78020cb1f49f 152 PRINTS PR00446 Hydrogen uptake protein signature 64 80 3.0E-11 T 13-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THITH_06775 ba8c97a9ef085e1f70ef78020cb1f49f 152 PRINTS PR00446 Hydrogen uptake protein signature 32 49 3.0E-11 T 13-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THITH_06775 ba8c97a9ef085e1f70ef78020cb1f49f 152 SUPERFAMILY SSF53163 1 150 4.97E-37 T 13-10-2018 IPR023430 Peptidase HybD-like domain superfamily THITH_06775 ba8c97a9ef085e1f70ef78020cb1f49f 152 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 1 145 1.8E-37 T 13-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THITH_06775 ba8c97a9ef085e1f70ef78020cb1f49f 152 Gene3D G3DSA:3.40.50.1450 1 152 2.2E-37 T 13-10-2018 IPR023430 Peptidase HybD-like domain superfamily THITH_06775 ba8c97a9ef085e1f70ef78020cb1f49f 152 Pfam PF01750 Hydrogenase maturation protease 17 145 1.7E-22 T 13-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 Hamap MF_02004 Valine--tRNA ligase [valS]. 1 919 16.031 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 Gene3D G3DSA:3.40.50.620 2 195 1.7E-59 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 PRINTS PR00986 Valyl-tRNA synthetase signature 344 357 2.2E-38 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 PRINTS PR00986 Valyl-tRNA synthetase signature 228 245 2.2E-38 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 PRINTS PR00986 Valyl-tRNA synthetase signature 444 465 2.2E-38 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 PRINTS PR00986 Valyl-tRNA synthetase signature 475 493 2.2E-38 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 PRINTS PR00986 Valyl-tRNA synthetase signature 34 45 2.2E-38 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 14 600 7.3E-212 T 13-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 41 52 - T 13-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 SUPERFAMILY SSF50677 189 340 2.49E-63 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 SUPERFAMILY SSF52374 2 610 1.57E-132 T 13-10-2018 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 Gene3D G3DSA:3.40.50.620 333 562 1.8E-63 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 Gene3D G3DSA:3.90.740.10 196 332 1.8E-53 T 13-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 SUPERFAMILY SSF47323 611 869 1.76E-63 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 Pfam PF08264 Anticodon-binding domain of tRNA 643 795 3.5E-38 T 13-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 Gene3D G3DSA:1.10.730.10 604 786 5.1E-52 T 13-10-2018 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 854 918 8.3E-17 T 13-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 SUPERFAMILY SSF46589 854 918 1.1E-14 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 Gene3D G3DSA:1.10.287.380 847 919 2.9E-21 T 13-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 THITH_03805 8bb83b2d133bb9f72c031b604a20be99 921 TIGRFAM TIGR00422 valS: valine--tRNA ligase 1 900 0.0 T 13-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 THITH_03880 3d686d2808bb74ac49aa1751cc394290 142 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 141 29.779 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 THITH_03880 3d686d2808bb74ac49aa1751cc394290 142 PIRSF PIRSF002181 1 142 3.6E-52 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 THITH_03880 3d686d2808bb74ac49aa1751cc394290 142 Pfam PF00572 Ribosomal protein L13 15 138 1.2E-59 T 13-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 THITH_03880 3d686d2808bb74ac49aa1751cc394290 142 SUPERFAMILY SSF52161 1 139 9.68E-63 T 13-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 THITH_03880 3d686d2808bb74ac49aa1751cc394290 142 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 13-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 THITH_03880 3d686d2808bb74ac49aa1751cc394290 142 Gene3D G3DSA:3.90.1180.10 1 142 1.6E-66 T 13-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 THITH_03880 3d686d2808bb74ac49aa1751cc394290 142 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 6 141 1.3E-66 T 13-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03850 7f9a2da20ce5a8c1ba44e56b2a1c47dd 750 Gene3D G3DSA:2.120.10.90 504 746 2.7E-15 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal THITH_03850 7f9a2da20ce5a8c1ba44e56b2a1c47dd 750 SUPERFAMILY SSF101904 505 745 1.83E-47 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal THITH_03850 7f9a2da20ce5a8c1ba44e56b2a1c47dd 750 Hamap MF_00936 DNA topoisomerase 4 subunit A [parC]. 8 747 34.199 T 13-10-2018 IPR005742 DNA topoisomerase IV, subunit A, Gram-negative GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_03850 7f9a2da20ce5a8c1ba44e56b2a1c47dd 750 Gene3D G3DSA:1.10.268.10 373 458 4.3E-177 T 13-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 THITH_03850 7f9a2da20ce5a8c1ba44e56b2a1c47dd 750 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 36 469 1.9E-131 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THITH_03850 7f9a2da20ce5a8c1ba44e56b2a1c47dd 750 Gene3D G3DSA:3.30.1360.40 242 335 4.3E-177 T 13-10-2018 THITH_03850 7f9a2da20ce5a8c1ba44e56b2a1c47dd 750 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 649 700 1.2E-7 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THITH_03850 7f9a2da20ce5a8c1ba44e56b2a1c47dd 750 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 556 593 0.14 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THITH_03850 7f9a2da20ce5a8c1ba44e56b2a1c47dd 750 TIGRFAM TIGR01062 parC_Gneg: DNA topoisomerase IV, A subunit 12 746 0.0 T 13-10-2018 THITH_03850 7f9a2da20ce5a8c1ba44e56b2a1c47dd 750 SUPERFAMILY SSF56719 35 487 3.66E-154 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 THITH_03850 7f9a2da20ce5a8c1ba44e56b2a1c47dd 750 Gene3D G3DSA:3.90.199.10 36 485 4.3E-177 T 13-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 THITH_03850 7f9a2da20ce5a8c1ba44e56b2a1c47dd 750 SMART SM00434 15 465 4.6E-229 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THITH_13295 ffa73bb0251545e86f075de3e61d920a 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 435 455 2.1E-8 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_13295 ffa73bb0251545e86f075de3e61d920a 461 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 418 435 2.1E-8 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_13295 ffa73bb0251545e86f075de3e61d920a 461 Gene3D G3DSA:1.10.8.60 314 387 8.3E-20 T 13-10-2018 THITH_13295 ffa73bb0251545e86f075de3e61d920a 461 SUPERFAMILY SSF52540 144 387 4.6E-71 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13295 ffa73bb0251545e86f075de3e61d920a 461 SUPERFAMILY SSF46689 357 454 1.37E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_13295 ffa73bb0251545e86f075de3e61d920a 461 Pfam PF00072 Response regulator receiver domain 5 114 1.7E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_13295 ffa73bb0251545e86f075de3e61d920a 461 Pfam PF02954 Bacterial regulatory protein, Fis family 412 452 8.5E-13 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_13295 ffa73bb0251545e86f075de3e61d920a 461 Gene3D G3DSA:1.10.10.60 388 455 2.0E-14 T 13-10-2018 THITH_13295 ffa73bb0251545e86f075de3e61d920a 461 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 229 244 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THITH_13295 ffa73bb0251545e86f075de3e61d920a 461 SUPERFAMILY SSF52172 4 188 1.25E-45 T 13-10-2018 IPR011006 CheY-like superfamily THITH_13295 ffa73bb0251545e86f075de3e61d920a 461 SMART SM00382 163 306 6.2E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_13295 ffa73bb0251545e86f075de3e61d920a 461 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 356 365 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site THITH_13295 ffa73bb0251545e86f075de3e61d920a 461 Gene3D G3DSA:3.40.50.300 137 313 9.9E-67 T 13-10-2018 THITH_13295 ffa73bb0251545e86f075de3e61d920a 461 Gene3D G3DSA:3.40.50.2300 2 136 2.2E-40 T 13-10-2018 THITH_13295 ffa73bb0251545e86f075de3e61d920a 461 Pfam PF00158 Sigma-54 interaction domain 143 309 1.1E-70 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THITH_13295 ffa73bb0251545e86f075de3e61d920a 461 SMART SM00448 3 114 1.9E-37 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_13320 1452dce48a5258a1023b9451b52d7fcd 404 Pfam PF02687 FtsX-like permease family 308 394 2.1E-12 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THITH_13320 1452dce48a5258a1023b9451b52d7fcd 404 Pfam PF12704 MacB-like periplasmic core domain 18 272 1.2E-12 T 13-10-2018 IPR025857 MacB-like periplasmic core domain THITH_05080 9a9fa65b9d2ef428c62418e6cd2a3649 131 SUPERFAMILY SSF55718 1 130 1.27E-22 T 13-10-2018 IPR036527 SCP2 sterol-binding domain superfamily THITH_05080 9a9fa65b9d2ef428c62418e6cd2a3649 131 Gene3D G3DSA:3.30.1050.10 2 126 3.8E-9 T 13-10-2018 IPR036527 SCP2 sterol-binding domain superfamily THITH_06000 cb9a50b8f2ab88857bac302d73e487b4 140 SMART SM00670 1 117 3.3E-5 T 13-10-2018 IPR002716 PIN domain THITH_06000 cb9a50b8f2ab88857bac302d73e487b4 140 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 2 118 1.4E-19 T 13-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component THITH_06000 cb9a50b8f2ab88857bac302d73e487b4 140 SUPERFAMILY SSF88723 2 131 5.49E-9 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_06000 cb9a50b8f2ab88857bac302d73e487b4 140 Gene3D G3DSA:3.40.50.1010 2 135 2.9E-5 T 13-10-2018 THITH_06000 cb9a50b8f2ab88857bac302d73e487b4 140 Pfam PF13470 PIN domain 2 112 3.6E-22 T 13-10-2018 IPR002716 PIN domain THITH_12605 9220b50fe89e34eb93877f9e60207268 233 Gene3D G3DSA:1.10.287.460 25 90 1.1E-13 T 13-10-2018 IPR036944 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily GO:0006457 THITH_12605 9220b50fe89e34eb93877f9e60207268 233 Pfam PF01346 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase 18 133 4.9E-28 T 13-10-2018 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal GO:0006457 THITH_12605 9220b50fe89e34eb93877f9e60207268 233 Gene3D G3DSA:3.10.50.40 91 233 3.8E-48 T 13-10-2018 THITH_12605 9220b50fe89e34eb93877f9e60207268 233 SUPERFAMILY SSF54534 28 231 1.28E-52 T 13-10-2018 THITH_12605 9220b50fe89e34eb93877f9e60207268 233 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 143 229 3.1E-26 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain THITH_06835 c1d6847772e8b9959345cec8082762c7 77 Pfam PF01455 HupF/HypC family 1 66 2.0E-27 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THITH_06835 c1d6847772e8b9959345cec8082762c7 77 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 71 1.9E-24 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THITH_06835 c1d6847772e8b9959345cec8082762c7 77 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 5.7E-23 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THITH_06835 c1d6847772e8b9959345cec8082762c7 77 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 57 69 5.7E-23 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THITH_06835 c1d6847772e8b9959345cec8082762c7 77 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 18 34 5.7E-23 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THITH_06835 c1d6847772e8b9959345cec8082762c7 77 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 39 55 5.7E-23 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THITH_06835 c1d6847772e8b9959345cec8082762c7 77 SUPERFAMILY SSF159127 1 70 1.83E-24 T 13-10-2018 IPR037254 HupF/HypC superfamily THITH_06835 c1d6847772e8b9959345cec8082762c7 77 Gene3D G3DSA:2.40.50.970 1 73 4.2E-28 T 13-10-2018 IPR037254 HupF/HypC superfamily THITH_06835 c1d6847772e8b9959345cec8082762c7 77 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 13-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site THITH_10480 604393a74de1cb655d7babf8dae26e60 822 Gene3D G3DSA:3.40.50.300 177 344 4.8E-54 T 13-10-2018 THITH_10480 604393a74de1cb655d7babf8dae26e60 822 Gene3D G3DSA:3.40.50.300 1 176 1.4E-51 T 13-10-2018 THITH_10480 604393a74de1cb655d7babf8dae26e60 822 PIRSF PIRSF005496 1 822 0.0 T 13-10-2018 THITH_10480 604393a74de1cb655d7babf8dae26e60 822 SUPERFAMILY SSF52540 12 337 7.76E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_10480 604393a74de1cb655d7babf8dae26e60 822 SMART SM00847 385 478 2.0E-12 T 13-10-2018 IPR007502 Helicase-associated domain GO:0004386 THITH_10480 604393a74de1cb655d7babf8dae26e60 822 Pfam PF04408 Helicase associated domain (HA2) 386 480 9.0E-14 T 13-10-2018 IPR007502 Helicase-associated domain GO:0004386 THITH_10480 604393a74de1cb655d7babf8dae26e60 822 SMART SM00490 224 326 1.4E-22 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_10480 604393a74de1cb655d7babf8dae26e60 822 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 1 819 0.0 T 13-10-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 THITH_10480 604393a74de1cb655d7babf8dae26e60 822 Pfam PF00271 Helicase conserved C-terminal domain 210 326 3.9E-18 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_10480 604393a74de1cb655d7babf8dae26e60 822 Pfam PF00270 DEAD/DEAH box helicase 19 162 1.8E-8 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THITH_10480 604393a74de1cb655d7babf8dae26e60 822 Gene3D G3DSA:1.20.120.1080 369 470 1.9E-11 T 13-10-2018 THITH_10480 604393a74de1cb655d7babf8dae26e60 822 SMART SM00487 2 183 1.7E-16 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_10480 604393a74de1cb655d7babf8dae26e60 822 Pfam PF08482 ATP-dependent helicase C-terminal 676 808 5.3E-55 T 13-10-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal THITH_12630 c31b7e38daa9cee1e593639387039f82 396 SUPERFAMILY SSF47090 326 392 2.56E-18 T 13-10-2018 IPR036365 PGBD-like superfamily THITH_12630 c31b7e38daa9cee1e593639387039f82 396 SUPERFAMILY SSF53955 10 322 2.06E-100 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily THITH_12630 c31b7e38daa9cee1e593639387039f82 396 Pfam PF13406 Transglycosylase SLT domain 25 316 1.4E-105 T 13-10-2018 IPR031304 Transglycosylase SLT domain 2 THITH_12630 c31b7e38daa9cee1e593639387039f82 396 TIGRFAM TIGR02283 MltB_2: lytic murein transglycosylase 24 320 7.0E-107 T 13-10-2018 IPR011970 Lytic murein transglycosylase THITH_12630 c31b7e38daa9cee1e593639387039f82 396 Gene3D G3DSA:1.10.530.10 67 315 1.2E-82 T 13-10-2018 THITH_12630 c31b7e38daa9cee1e593639387039f82 396 Gene3D G3DSA:1.10.8.350 34 200 1.2E-82 T 13-10-2018 THITH_12630 c31b7e38daa9cee1e593639387039f82 396 Gene3D G3DSA:1.10.101.10 326 395 5.3E-15 T 13-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 THITH_12630 c31b7e38daa9cee1e593639387039f82 396 Pfam PF01471 Putative peptidoglycan binding domain 337 392 5.0E-14 T 13-10-2018 IPR002477 Peptidoglycan binding-like THITH_17050 b9e5eaa021ef9b6bba01bbc51a33f91f 427 Pfam PF12899 Alkaline and neutral invertase 252 410 7.4E-9 T 13-10-2018 IPR024746 Glycosyl hydrolase family 100 GO:0033926 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 THITH_17050 b9e5eaa021ef9b6bba01bbc51a33f91f 427 SUPERFAMILY SSF48208 19 419 1.33E-36 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 THITH_02415 2d0a9cda29d1b76691b0770ab6772db9 421 Gene3D G3DSA:3.40.50.11720 39 209 6.4E-44 T 13-10-2018 IPR038107 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal domain superfamily KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 THITH_02415 2d0a9cda29d1b76691b0770ab6772db9 421 Pfam PF04413 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) 34 210 8.4E-57 T 13-10-2018 IPR007507 3-deoxy-D-manno-octulosonic-acid transferase, N-terminal KEGG: 00540+2.4.99.12|MetaCyc: PWY-7675 THITH_02415 2d0a9cda29d1b76691b0770ab6772db9 421 Pfam PF00534 Glycosyl transferases group 1 296 398 1.8E-7 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 THITH_02415 2d0a9cda29d1b76691b0770ab6772db9 421 SUPERFAMILY SSF53756 63 400 1.0E-12 T 13-10-2018 THITH_02415 2d0a9cda29d1b76691b0770ab6772db9 421 Gene3D G3DSA:3.40.50.2000 217 401 3.9E-60 T 13-10-2018 THITH_06090 d79df099b4995d819429cf29a2e606d8 315 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 12 298 29.396 T 13-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 THITH_06090 d79df099b4995d819429cf29a2e606d8 315 Pfam PF02355 Protein export membrane protein 121 295 1.3E-67 T 13-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial THITH_06090 d79df099b4995d819429cf29a2e606d8 315 PRINTS PR01755 Bacterial translocase SecF protein signature 39 54 8.9E-34 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THITH_06090 d79df099b4995d819429cf29a2e606d8 315 PRINTS PR01755 Bacterial translocase SecF protein signature 155 169 8.9E-34 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THITH_06090 d79df099b4995d819429cf29a2e606d8 315 PRINTS PR01755 Bacterial translocase SecF protein signature 203 221 8.9E-34 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THITH_06090 d79df099b4995d819429cf29a2e606d8 315 PRINTS PR01755 Bacterial translocase SecF protein signature 235 250 8.9E-34 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THITH_06090 d79df099b4995d819429cf29a2e606d8 315 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 104 284 1.2E-56 T 13-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial THITH_06090 d79df099b4995d819429cf29a2e606d8 315 Pfam PF07549 SecD/SecF GG Motif 35 57 3.3E-9 T 13-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site THITH_06090 d79df099b4995d819429cf29a2e606d8 315 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 40 287 2.3E-82 T 13-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 THITH_06090 d79df099b4995d819429cf29a2e606d8 315 Gene3D G3DSA:1.20.1640.10 109 301 2.1E-11 T 13-10-2018 THITH_06090 d79df099b4995d819429cf29a2e606d8 315 SUPERFAMILY SSF82866 74 295 7.98E-41 T 13-10-2018 THITH_10915 37263664ffb0246af1fea5b53e89f0e3 290 Pfam PF02577 Bifunctional nuclease 43 164 1.8E-35 T 13-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 THITH_10915 37263664ffb0246af1fea5b53e89f0e3 290 SUPERFAMILY SSF50156 183 269 3.15E-9 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 THITH_10915 37263664ffb0246af1fea5b53e89f0e3 290 SUPERFAMILY SSF103256 37 163 3.92E-31 T 13-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 THITH_10915 37263664ffb0246af1fea5b53e89f0e3 290 Gene3D G3DSA:2.30.42.60 178 285 2.9E-14 T 13-10-2018 THITH_10915 37263664ffb0246af1fea5b53e89f0e3 290 Gene3D G3DSA:3.10.690.10 32 170 9.1E-40 T 13-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 THITH_10830 331fc84005831a6b64899e5c8a767ea5 316 Gene3D G3DSA:1.10.10.10 1 84 2.5E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_10830 331fc84005831a6b64899e5c8a767ea5 316 SUPERFAMILY SSF53850 93 294 5.27E-29 T 13-10-2018 THITH_10830 331fc84005831a6b64899e5c8a767ea5 316 Gene3D G3DSA:3.40.190.10 165 262 1.9E-19 T 13-10-2018 THITH_10830 331fc84005831a6b64899e5c8a767ea5 316 Gene3D G3DSA:3.40.190.10 98 269 1.9E-19 T 13-10-2018 THITH_10830 331fc84005831a6b64899e5c8a767ea5 316 Pfam PF03466 LysR substrate binding domain 91 283 2.5E-24 T 13-10-2018 IPR005119 LysR, substrate-binding THITH_10830 331fc84005831a6b64899e5c8a767ea5 316 SUPERFAMILY SSF46785 5 87 3.47E-17 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_10830 331fc84005831a6b64899e5c8a767ea5 316 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 5.7E-16 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_15855 1e47e1d0d81e751e9a06a6fdc0e31c2d 343 SUPERFAMILY SSF52418 74 340 6.8E-96 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 THITH_15855 1e47e1d0d81e751e9a06a6fdc0e31c2d 343 SUPERFAMILY SSF47648 2 70 8.63E-19 T 13-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 THITH_15855 1e47e1d0d81e751e9a06a6fdc0e31c2d 343 Gene3D G3DSA:1.20.970.10 1 70 2.1E-27 T 13-10-2018 THITH_15855 1e47e1d0d81e751e9a06a6fdc0e31c2d 343 Pfam PF02885 Glycosyl transferase family, helical bundle domain 5 64 1.6E-17 T 13-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 THITH_15855 1e47e1d0d81e751e9a06a6fdc0e31c2d 343 Gene3D G3DSA:3.40.1030.10 72 341 7.1E-108 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 THITH_15855 1e47e1d0d81e751e9a06a6fdc0e31c2d 343 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 8 333 1.7E-127 T 13-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 THITH_15855 1e47e1d0d81e751e9a06a6fdc0e31c2d 343 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 5 334 38.743 T 13-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 THITH_15855 1e47e1d0d81e751e9a06a6fdc0e31c2d 343 Pfam PF00591 Glycosyl transferase family, a/b domain 75 324 9.0E-95 T 13-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 THITH_11900 995f5eef801e782f7aac17ab7f1cb1f8 204 Pfam PF09976 Tetratricopeptide repeat-like domain 14 203 2.8E-50 T 13-10-2018 IPR018704 Tetratricopeptide repeat-like domain Reactome: R-HSA-192823|Reactome: R-HSA-381038|Reactome: R-HSA-381426|Reactome: R-HSA-6798695|Reactome: R-HSA-8957275 THITH_11900 995f5eef801e782f7aac17ab7f1cb1f8 204 PIRSF PIRSF006170 1 204 1.6E-50 T 13-10-2018 IPR026039 Uncharacterised protein family UPF0070 THITH_11900 995f5eef801e782f7aac17ab7f1cb1f8 204 Gene3D G3DSA:1.25.40.10 49 204 1.4E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_11900 995f5eef801e782f7aac17ab7f1cb1f8 204 SUPERFAMILY SSF48452 37 194 3.35E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_11735 804a71242170148f5787bc87dbfa36d9 290 Pfam PF00005 ABC transporter 38 193 5.2E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_11735 804a71242170148f5787bc87dbfa36d9 290 Gene3D G3DSA:3.40.50.300 22 288 8.3E-60 T 13-10-2018 THITH_11735 804a71242170148f5787bc87dbfa36d9 290 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_11735 804a71242170148f5787bc87dbfa36d9 290 SMART SM00382 47 243 1.8E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_11735 804a71242170148f5787bc87dbfa36d9 290 SUPERFAMILY SSF52540 23 255 3.55E-57 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01235 8ca3a5b49f33279dd23b3c582a784332 263 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 1 9 - T 13-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 THITH_01235 8ca3a5b49f33279dd23b3c582a784332 263 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 190 206 - T 13-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 THITH_01235 8ca3a5b49f33279dd23b3c582a784332 263 ProSitePatterns PS01090 TatD deoxyribonuclease family signature 2. 127 137 - T 13-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 THITH_01235 8ca3a5b49f33279dd23b3c582a784332 263 Gene3D G3DSA:3.20.20.140 1 256 2.4E-74 T 13-10-2018 THITH_01235 8ca3a5b49f33279dd23b3c582a784332 263 Pfam PF01026 TatD related DNase 2 253 1.6E-59 T 13-10-2018 IPR001130 TatD family GO:0016788 THITH_01235 8ca3a5b49f33279dd23b3c582a784332 263 SUPERFAMILY SSF51556 1 255 7.96E-73 T 13-10-2018 IPR032466 Metal-dependent hydrolase THITH_01235 8ca3a5b49f33279dd23b3c582a784332 263 PIRSF PIRSF005902 1 258 6.4E-56 T 13-10-2018 IPR001130 TatD family GO:0016788 THITH_09640 0e13272c1fb7f3c9d470b48bfb27c518 246 Pfam PF05209 Septum formation inhibitor MinC, N-terminal domain 10 104 4.5E-14 T 13-10-2018 IPR007874 Septum formation inhibitor MinC, N-terminal GO:0051302 THITH_09640 0e13272c1fb7f3c9d470b48bfb27c518 246 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 10 244 24.442 T 13-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 THITH_09640 0e13272c1fb7f3c9d470b48bfb27c518 246 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 143 243 1.6E-29 T 13-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 THITH_09640 0e13272c1fb7f3c9d470b48bfb27c518 246 Gene3D G3DSA:2.160.20.70 138 246 1.1E-30 T 13-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 THITH_09640 0e13272c1fb7f3c9d470b48bfb27c518 246 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 10 245 1.2E-57 T 13-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 THITH_09640 0e13272c1fb7f3c9d470b48bfb27c518 246 SUPERFAMILY SSF63848 141 244 1.83E-28 T 13-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 THITH_09640 0e13272c1fb7f3c9d470b48bfb27c518 246 Gene3D G3DSA:3.30.750.120 6 121 1.1E-16 T 13-10-2018 IPR038061 MinC, Proteobacteria, N-terminal domain superfamily THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 SUPERFAMILY SSF53756 421 749 3.09E-8 T 13-10-2018 THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 Gene3D G3DSA:1.25.40.10 279 344 3.7E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 Gene3D G3DSA:1.25.40.10 171 278 1.0E-15 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 Gene3D G3DSA:3.40.50.11380 387 741 4.5E-149 T 13-10-2018 THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 Pfam PF13432 Tetratricopeptide repeat 45 107 7.7E-8 T 13-10-2018 THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 Pfam PF13432 Tetratricopeptide repeat 287 339 0.0062 T 13-10-2018 THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 SMART SM00028 210 243 7.5 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 SMART SM00028 39 72 5.9E-4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 SMART SM00028 175 208 1.6 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 SMART SM00028 278 311 0.64 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 SMART SM00028 73 106 0.068 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 Gene3D G3DSA:1.25.40.10 3 170 2.4E-26 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 SUPERFAMILY SSF48452 17 307 2.01E-36 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 Gene3D G3DSA:3.40.50.2000 556 734 4.5E-149 T 13-10-2018 THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 Pfam PF14559 Tetratricopeptide repeat 221 278 5.1E-8 T 13-10-2018 THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 Pfam PF13181 Tetratricopeptide repeat 176 203 0.0045 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 Pfam PF13844 Glycosyl transferase family 41 558 752 5.4E-45 T 13-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 THITH_10145 8c1d2d27f19425c76656de6a67ad75c3 765 Pfam PF13844 Glycosyl transferase family 41 399 551 8.7E-47 T 13-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 THITH_16905 830f7aca80b216f76ccbbc997daaf369 459 Gene3D G3DSA:3.30.70.270 6 188 5.5E-57 T 13-10-2018 THITH_16905 830f7aca80b216f76ccbbc997daaf369 459 Pfam PF00563 EAL domain 192 426 1.6E-76 T 13-10-2018 IPR001633 EAL domain THITH_16905 830f7aca80b216f76ccbbc997daaf369 459 Gene3D G3DSA:3.20.20.450 189 441 5.0E-105 T 13-10-2018 IPR035919 EAL domain superfamily THITH_16905 830f7aca80b216f76ccbbc997daaf369 459 SUPERFAMILY SSF141868 191 440 3.79E-92 T 13-10-2018 IPR035919 EAL domain superfamily THITH_16905 830f7aca80b216f76ccbbc997daaf369 459 SUPERFAMILY SSF55073 17 177 1.8E-45 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_16905 830f7aca80b216f76ccbbc997daaf369 459 SMART SM00267 1 176 4.7E-62 T 13-10-2018 IPR000160 GGDEF domain THITH_16905 830f7aca80b216f76ccbbc997daaf369 459 SMART SM00052 186 432 9.8E-125 T 13-10-2018 IPR001633 EAL domain THITH_16905 830f7aca80b216f76ccbbc997daaf369 459 Pfam PF00990 Diguanylate cyclase, GGDEF domain 12 172 1.1E-47 T 13-10-2018 IPR000160 GGDEF domain THITH_16905 830f7aca80b216f76ccbbc997daaf369 459 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 8 173 1.1E-41 T 13-10-2018 IPR000160 GGDEF domain THITH_14120 74fc66c14ea501fa3d86c4b7cfaaa2aa 482 Pfam PF00795 Carbon-nitrogen hydrolase 208 447 7.2E-30 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 THITH_14120 74fc66c14ea501fa3d86c4b7cfaaa2aa 482 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 49 429 1.6E-86 T 13-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 THITH_14120 74fc66c14ea501fa3d86c4b7cfaaa2aa 482 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 1 466 21.006 T 13-10-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 THITH_14120 74fc66c14ea501fa3d86c4b7cfaaa2aa 482 SUPERFAMILY SSF56317 203 461 1.15E-40 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily THITH_14120 74fc66c14ea501fa3d86c4b7cfaaa2aa 482 Gene3D G3DSA:3.60.110.10 204 452 3.3E-12 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily THITH_11235 1b699fb297d06e6de4f4362cd3bec301 206 Gene3D G3DSA:1.10.1670.40 13 197 2.7E-66 T 13-10-2018 THITH_11235 1b699fb297d06e6de4f4362cd3bec301 206 SUPERFAMILY SSF48150 28 199 1.05E-45 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 THITH_11235 1b699fb297d06e6de4f4362cd3bec301 206 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 45 181 2.1E-17 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THITH_11235 1b699fb297d06e6de4f4362cd3bec301 206 Gene3D G3DSA:1.10.340.30 38 147 2.7E-66 T 13-10-2018 THITH_11235 1b699fb297d06e6de4f4362cd3bec301 206 SMART SM00478 48 200 2.0E-14 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THITH_17495 83a33205daabf02b6a1f4e0310eb068b 435 Gene3D G3DSA:3.40.50.300 217 367 2.2E-86 T 13-10-2018 THITH_17495 83a33205daabf02b6a1f4e0310eb068b 435 SUPERFAMILY SSF52540 73 357 5.58E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_17495 83a33205daabf02b6a1f4e0310eb068b 435 PRINTS PR00449 Transforming protein P21 ras signature 318 331 1.5E-5 T 13-10-2018 THITH_17495 83a33205daabf02b6a1f4e0310eb068b 435 PRINTS PR00449 Transforming protein P21 ras signature 217 238 1.5E-5 T 13-10-2018 THITH_17495 83a33205daabf02b6a1f4e0310eb068b 435 Gene3D G3DSA:1.20.120.430 122 435 2.2E-86 T 13-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 THITH_17495 83a33205daabf02b6a1f4e0310eb068b 435 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 6 435 30.305 T 13-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 THITH_17495 83a33205daabf02b6a1f4e0310eb068b 435 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 218 331 1.3E-19 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THITH_17495 83a33205daabf02b6a1f4e0310eb068b 435 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 12 435 6.8E-91 T 13-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 THITH_17495 83a33205daabf02b6a1f4e0310eb068b 435 Pfam PF10396 GTP-binding protein TrmE N-terminus 7 120 4.3E-34 T 13-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 THITH_17495 83a33205daabf02b6a1f4e0310eb068b 435 Pfam PF01926 50S ribosome-binding GTPase 219 305 2.9E-21 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_17495 83a33205daabf02b6a1f4e0310eb068b 435 Gene3D G3DSA:3.30.1360.120 1 121 3.3E-39 T 13-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THITH_17495 83a33205daabf02b6a1f4e0310eb068b 435 Pfam PF12631 MnmE helical domain 123 432 9.6E-41 T 13-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 THITH_11275 3924a8560874fbc2dc735fea2bd207c9 607 Pfam PF00723 Glycosyl hydrolases family 15 230 540 1.9E-36 T 13-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 THITH_11275 3924a8560874fbc2dc735fea2bd207c9 607 Pfam PF00723 Glycosyl hydrolases family 15 547 594 6.0E-6 T 13-10-2018 IPR011613 GH15-like domain Reactome: R-HSA-70221 THITH_11275 3924a8560874fbc2dc735fea2bd207c9 607 Gene3D G3DSA:1.50.10.10 230 604 1.2E-87 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 THITH_11275 3924a8560874fbc2dc735fea2bd207c9 607 SUPERFAMILY SSF48208 205 600 1.06E-91 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 THITH_09020 3841a6de5560ae8731f4b9faf019c9fa 475 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 94 108 6.2E-28 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 THITH_09020 3841a6de5560ae8731f4b9faf019c9fa 475 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 228 248 6.2E-28 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 THITH_09020 3841a6de5560ae8731f4b9faf019c9fa 475 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 178 200 6.2E-28 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 THITH_09020 3841a6de5560ae8731f4b9faf019c9fa 475 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 357 368 6.2E-28 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 THITH_09020 3841a6de5560ae8731f4b9faf019c9fa 475 Gene3D G3DSA:3.40.50.720 187 475 4.0E-78 T 13-10-2018 THITH_09020 3841a6de5560ae8731f4b9faf019c9fa 475 Gene3D G3DSA:3.40.50.10860 40 186 7.9E-54 T 13-10-2018 THITH_09020 3841a6de5560ae8731f4b9faf019c9fa 475 SUPERFAMILY SSF51735 191 474 1.11E-54 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_09020 3841a6de5560ae8731f4b9faf019c9fa 475 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 102 115 - T 13-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 THITH_09020 3841a6de5560ae8731f4b9faf019c9fa 475 SUPERFAMILY SSF53223 8 189 1.12E-51 T 13-10-2018 THITH_09020 3841a6de5560ae8731f4b9faf019c9fa 475 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 40 166 1.0E-48 T 13-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 THITH_09020 3841a6de5560ae8731f4b9faf019c9fa 475 SMART SM00839 188 473 2.1E-72 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 THITH_09020 3841a6de5560ae8731f4b9faf019c9fa 475 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 187 374 2.8E-42 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 THITH_09020 3841a6de5560ae8731f4b9faf019c9fa 475 PIRSF PIRSF000185 5 475 1.9E-133 T 13-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 THITH_06145 5388a1aeaffa33367c29c74fc5825594 415 SUPERFAMILY SSF54862 18 120 2.26E-18 T 13-10-2018 THITH_06145 5388a1aeaffa33367c29c74fc5825594 415 Gene3D G3DSA:1.10.1060.10 2 109 1.0E-11 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_06145 5388a1aeaffa33367c29c74fc5825594 415 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 79 90 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_06145 5388a1aeaffa33367c29c74fc5825594 415 Pfam PF02754 Cysteine-rich domain 308 390 4.0E-13 T 13-10-2018 IPR004017 Cysteine-rich domain THITH_06145 5388a1aeaffa33367c29c74fc5825594 415 Pfam PF02754 Cysteine-rich domain 178 260 3.8E-11 T 13-10-2018 IPR004017 Cysteine-rich domain THITH_06145 5388a1aeaffa33367c29c74fc5825594 415 PIRSF PIRSF000139 5 414 1.1E-110 T 13-10-2018 THITH_06145 5388a1aeaffa33367c29c74fc5825594 415 Pfam PF12838 4Fe-4S dicluster domain 24 93 2.3E-12 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_09590 f68e425b65e1b555ec8773ec78e74e89 1163 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1156 22.628 T 13-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 THITH_09590 f68e425b65e1b555ec8773ec78e74e89 1163 SUPERFAMILY SSF52540 3 1139 2.1E-48 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_09590 f68e425b65e1b555ec8773ec78e74e89 1163 PIRSF PIRSF005719 579 1163 3.8E-123 T 13-10-2018 IPR024704 Structural maintenance of chromosomes protein THITH_09590 f68e425b65e1b555ec8773ec78e74e89 1163 PIRSF PIRSF005719 1 557 1.4E-125 T 13-10-2018 IPR024704 Structural maintenance of chromosomes protein THITH_09590 f68e425b65e1b555ec8773ec78e74e89 1163 Gene3D G3DSA:3.40.50.300 1 250 5.9E-49 T 13-10-2018 THITH_09590 f68e425b65e1b555ec8773ec78e74e89 1163 SUPERFAMILY SSF52540 808 1156 5.63E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_09590 f68e425b65e1b555ec8773ec78e74e89 1163 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1154 0.0 T 13-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 THITH_09590 f68e425b65e1b555ec8773ec78e74e89 1163 Gene3D G3DSA:3.40.50.300 937 1162 1.5E-44 T 13-10-2018 THITH_09590 f68e425b65e1b555ec8773ec78e74e89 1163 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1147 8.4E-63 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal THITH_08610 c4175d3158f8e857e6aab1339718e0bc 688 SUPERFAMILY SSF52540 17 426 1.45E-139 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_08610 c4175d3158f8e857e6aab1339718e0bc 688 Pfam PF12344 Ultra-violet resistance protein B 563 604 8.7E-22 T 13-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain THITH_08610 c4175d3158f8e857e6aab1339718e0bc 688 Gene3D G3DSA:3.40.50.300 426 607 1.4E-50 T 13-10-2018 THITH_08610 c4175d3158f8e857e6aab1339718e0bc 688 SMART SM00487 21 437 6.4E-27 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_08610 c4175d3158f8e857e6aab1339718e0bc 688 SUPERFAMILY SSF52540 47 594 2.27E-37 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_08610 c4175d3158f8e857e6aab1339718e0bc 688 Gene3D G3DSA:3.40.50.300 8 248 2.2E-73 T 13-10-2018 THITH_08610 c4175d3158f8e857e6aab1339718e0bc 688 SMART SM00490 471 557 2.1E-20 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_08610 c4175d3158f8e857e6aab1339718e0bc 688 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 18 673 0.0 T 13-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 THITH_08610 c4175d3158f8e857e6aab1339718e0bc 688 Gene3D G3DSA:3.40.50.300 282 425 1.8E-51 T 13-10-2018 THITH_08610 c4175d3158f8e857e6aab1339718e0bc 688 Hamap MF_00204 UvrABC system protein B [uvrB]. 15 675 43.7 T 13-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 THITH_08610 c4175d3158f8e857e6aab1339718e0bc 688 Gene3D G3DSA:4.10.860.10 626 678 1.2E-14 T 13-10-2018 THITH_08610 c4175d3158f8e857e6aab1339718e0bc 688 Pfam PF00271 Helicase conserved C-terminal domain 452 555 8.0E-18 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_08610 c4175d3158f8e857e6aab1339718e0bc 688 Pfam PF04851 Type III restriction enzyme, res subunit 27 104 4.9E-9 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THITH_08610 c4175d3158f8e857e6aab1339718e0bc 688 SUPERFAMILY SSF46600 635 675 1.7E-11 T 13-10-2018 IPR036876 UVR domain superfamily THITH_08610 c4175d3158f8e857e6aab1339718e0bc 688 Pfam PF02151 UvrB/uvrC motif 641 674 9.2E-8 T 13-10-2018 IPR001943 UVR domain GO:0005515 THITH_13495 97a31f0c90ee9fb08c76aa01692631fc 287 SUPERFAMILY SSF48452 122 252 2.73E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_13495 97a31f0c90ee9fb08c76aa01692631fc 287 SUPERFAMILY SSF52833 7 115 8.02E-37 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_13495 97a31f0c90ee9fb08c76aa01692631fc 287 Pfam PF14561 Tetratricopeptide repeat 200 287 7.4E-22 T 13-10-2018 THITH_13495 97a31f0c90ee9fb08c76aa01692631fc 287 Pfam PF00085 Thioredoxin 11 111 7.1E-27 T 13-10-2018 IPR013766 Thioredoxin domain GO:0045454 THITH_13495 97a31f0c90ee9fb08c76aa01692631fc 287 Gene3D G3DSA:1.25.40.10 117 200 3.1E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_13495 97a31f0c90ee9fb08c76aa01692631fc 287 PRINTS PR00421 Thioredoxin family signature 77 88 1.1E-6 T 13-10-2018 THITH_13495 97a31f0c90ee9fb08c76aa01692631fc 287 PRINTS PR00421 Thioredoxin family signature 29 37 1.1E-6 T 13-10-2018 THITH_13495 97a31f0c90ee9fb08c76aa01692631fc 287 PRINTS PR00421 Thioredoxin family signature 37 46 1.1E-6 T 13-10-2018 THITH_13495 97a31f0c90ee9fb08c76aa01692631fc 287 TIGRFAM TIGR01068 thioredoxin: thioredoxin 17 112 9.8E-32 T 13-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 THITH_13495 97a31f0c90ee9fb08c76aa01692631fc 287 Pfam PF14559 Tetratricopeptide repeat 128 194 2.0E-8 T 13-10-2018 THITH_13495 97a31f0c90ee9fb08c76aa01692631fc 287 Gene3D G3DSA:3.40.30.10 8 116 3.4E-33 T 13-10-2018 THITH_13495 97a31f0c90ee9fb08c76aa01692631fc 287 Gene3D G3DSA:1.25.40.10 201 287 8.7E-25 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_04325 8c8d4a439106ebe88a2f32d17599a002 487 Gene3D G3DSA:1.10.579.10 300 481 1.4E-74 T 13-10-2018 THITH_04325 8c8d4a439106ebe88a2f32d17599a002 487 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 330 342 - T 13-10-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal THITH_04325 8c8d4a439106ebe88a2f32d17599a002 487 Pfam PF03441 FAD binding domain of DNA photolyase 281 477 1.2E-81 T 13-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 THITH_04325 8c8d4a439106ebe88a2f32d17599a002 487 Pfam PF00875 DNA photolyase 4 168 4.6E-53 T 13-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 THITH_04325 8c8d4a439106ebe88a2f32d17599a002 487 Gene3D G3DSA:1.25.40.80 131 292 2.1E-96 T 13-10-2018 THITH_04325 8c8d4a439106ebe88a2f32d17599a002 487 PRINTS PR00147 DNA photolyase signature 140 156 4.3E-22 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 THITH_04325 8c8d4a439106ebe88a2f32d17599a002 487 PRINTS PR00147 DNA photolyase signature 330 346 4.3E-22 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 THITH_04325 8c8d4a439106ebe88a2f32d17599a002 487 PRINTS PR00147 DNA photolyase signature 389 403 4.3E-22 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 THITH_04325 8c8d4a439106ebe88a2f32d17599a002 487 PRINTS PR00147 DNA photolyase signature 350 368 4.3E-22 T 13-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 THITH_04325 8c8d4a439106ebe88a2f32d17599a002 487 Gene3D G3DSA:3.40.50.620 5 211 2.1E-96 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_04325 8c8d4a439106ebe88a2f32d17599a002 487 SUPERFAMILY SSF52425 4 177 5.49E-57 T 13-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 THITH_04325 8c8d4a439106ebe88a2f32d17599a002 487 SUPERFAMILY SSF48173 200 479 1.06E-108 T 13-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 Gene3D G3DSA:3.40.190.10 30 263 4.1E-23 T 13-10-2018 THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 Gene3D G3DSA:1.10.3210.10 798 988 4.7E-68 T 13-10-2018 THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 SMART SM00091 481 549 2.9E-5 T 13-10-2018 IPR000014 PAS domain THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 SMART SM00091 368 436 2.2E-7 T 13-10-2018 IPR000014 PAS domain THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 Gene3D G3DSA:3.40.190.10 116 236 4.1E-23 T 13-10-2018 THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 Pfam PF01966 HD domain 824 945 7.7E-21 T 13-10-2018 IPR006674 HD domain THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 SUPERFAMILY SSF53850 43 224 2.15E-15 T 13-10-2018 THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 Pfam PF13185 GAF domain 625 770 2.6E-21 T 13-10-2018 IPR003018 GAF domain GO:0005515 THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 SMART SM00471 819 954 1.2E-8 T 13-10-2018 IPR003607 HD/PDEase domain THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 Gene3D G3DSA:2.10.70.100 551 599 6.3E-15 T 13-10-2018 THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 Pfam PF08447 PAS fold 504 591 4.6E-23 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 Pfam PF08448 PAS fold 374 437 3.9E-8 T 13-10-2018 IPR013656 PAS fold-4 THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 SMART SM00086 555 597 1.2E-4 T 13-10-2018 IPR001610 PAC motif THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 30 277 2.2E-44 T 13-10-2018 THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 Gene3D G3DSA:3.30.450.20 492 550 2.8E-24 T 13-10-2018 THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 SUPERFAMILY SSF55781 591 771 2.12E-22 T 13-10-2018 THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 SMART SM00065 626 781 1.9E-5 T 13-10-2018 IPR003018 GAF domain GO:0005515 THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 479 604 6.5E-10 T 13-10-2018 IPR000014 PAS domain THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 SUPERFAMILY SSF55785 491 599 4.36E-20 T 13-10-2018 IPR035965 PAS domain superfamily THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 Gene3D G3DSA:3.30.450.20 353 488 1.3E-11 T 13-10-2018 THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 SUPERFAMILY SSF55785 359 430 1.03E-10 T 13-10-2018 IPR035965 PAS domain superfamily THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 Gene3D G3DSA:3.30.450.40 600 787 7.9E-30 T 13-10-2018 IPR029016 GAF-like domain superfamily THITH_16865 da1ab7d074e5a8854e47fd79a544c5cb 1008 SUPERFAMILY SSF109604 808 983 6.57E-37 T 13-10-2018 THITH_02340 4c51620c10c0113d7f6a328599fedc0b 247 Pfam PF00175 Oxidoreductase NAD-binding domain 111 222 2.6E-13 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THITH_02340 4c51620c10c0113d7f6a328599fedc0b 247 Pfam PF00970 Oxidoreductase FAD-binding domain 20 90 1.9E-5 T 13-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 THITH_02340 4c51620c10c0113d7f6a328599fedc0b 247 Gene3D G3DSA:3.40.50.80 97 247 9.2E-39 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain THITH_02340 4c51620c10c0113d7f6a328599fedc0b 247 SUPERFAMILY SSF63380 3 93 1.38E-22 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel THITH_02340 4c51620c10c0113d7f6a328599fedc0b 247 Gene3D G3DSA:2.40.30.10 1 96 3.8E-25 T 13-10-2018 THITH_02340 4c51620c10c0113d7f6a328599fedc0b 247 SUPERFAMILY SSF52343 104 247 9.95E-33 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain THITH_12765 32b208630e473bd9a6d53506322cf544 149 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 4 139 4.3E-48 T 13-10-2018 THITH_12765 32b208630e473bd9a6d53506322cf544 149 SUPERFAMILY SSF82649 1 141 1.39E-47 T 13-10-2018 THITH_12765 32b208630e473bd9a6d53506322cf544 149 Gene3D G3DSA:3.90.1010.10 1 145 1.2E-52 T 13-10-2018 THITH_12765 32b208630e473bd9a6d53506322cf544 149 Pfam PF01592 NifU-like N terminal domain 8 127 7.4E-25 T 13-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 THITH_16560 96191904f0c483ae9f6f3fefc8a54184 91 Pfam PF04380 Membrane fusogenic activity 1 77 9.2E-28 T 13-10-2018 IPR007475 Membrane fusogenic activity THITH_12000 78ae7493682060c5a9493dcb5f395605 102 Pfam PF04077 DsrH like protein 9 98 2.8E-29 T 13-10-2018 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 THITH_12000 78ae7493682060c5a9493dcb5f395605 102 SUPERFAMILY SSF75169 2 101 3.66E-30 T 13-10-2018 IPR027396 DsrEFH-like THITH_12000 78ae7493682060c5a9493dcb5f395605 102 Gene3D G3DSA:3.40.1260.10 1 102 1.2E-35 T 13-10-2018 IPR027396 DsrEFH-like THITH_12000 78ae7493682060c5a9493dcb5f395605 102 TIGRFAM TIGR03011 sulf_tusB_dsrH: sulfur relay protein TusB/DsrH 4 101 2.2E-31 T 13-10-2018 IPR007215 Sulphur relay, TusB/DsrH GO:0002143|GO:0005737 THITH_05750 d44987cc0a4df882edc14074064bfce7 349 SUPERFAMILY SSF55347 138 289 9.65E-34 T 13-10-2018 THITH_05750 d44987cc0a4df882edc14074064bfce7 349 Gene3D G3DSA:3.40.50.720 11 319 8.8E-114 T 13-10-2018 THITH_05750 d44987cc0a4df882edc14074064bfce7 349 SUPERFAMILY SSF51735 6 164 4.72E-41 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_05750 d44987cc0a4df882edc14074064bfce7 349 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 10 127 1.2E-27 T 13-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 THITH_05750 d44987cc0a4df882edc14074064bfce7 349 Gene3D G3DSA:3.30.360.10 137 341 8.8E-114 T 13-10-2018 THITH_05750 d44987cc0a4df882edc14074064bfce7 349 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 141 254 1.9E-13 T 13-10-2018 IPR004104 Oxidoreductase, C-terminal GO:0016491|GO:0055114 THITH_00365 2720189e45179aaeba97763c943c9aaa 693 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 84 352 1.9E-13 T 13-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 THITH_00365 2720189e45179aaeba97763c943c9aaa 693 Gene3D G3DSA:3.40.1380.40 391 552 1.4E-10 T 13-10-2018 THITH_11840 ba8a24c1826637c6559d84755b72d917 250 Pfam PF00175 Oxidoreductase NAD-binding domain 111 216 3.9E-11 T 13-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 THITH_11840 ba8a24c1826637c6559d84755b72d917 250 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 50 57 1.1E-6 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THITH_11840 ba8a24c1826637c6559d84755b72d917 250 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 110 129 1.1E-6 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THITH_11840 ba8a24c1826637c6559d84755b72d917 250 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 204 212 1.1E-6 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THITH_11840 ba8a24c1826637c6559d84755b72d917 250 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 147 158 1.1E-6 T 13-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 THITH_11840 ba8a24c1826637c6559d84755b72d917 250 Pfam PF00970 Oxidoreductase FAD-binding domain 16 91 9.5E-7 T 13-10-2018 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Reactome: R-HSA-1237044 THITH_11840 ba8a24c1826637c6559d84755b72d917 250 Gene3D G3DSA:2.40.30.10 2 96 2.3E-28 T 13-10-2018 THITH_11840 ba8a24c1826637c6559d84755b72d917 250 Gene3D G3DSA:3.40.50.80 99 242 1.9E-36 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain THITH_11840 ba8a24c1826637c6559d84755b72d917 250 SUPERFAMILY SSF52343 103 242 2.49E-30 T 13-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain THITH_11840 ba8a24c1826637c6559d84755b72d917 250 SUPERFAMILY SSF63380 5 99 3.25E-21 T 13-10-2018 IPR017938 Riboflavin synthase-like beta-barrel THITH_10010 f1a4a10364f9bb0a7c92312325c6adb8 257 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 249 1.5E-71 T 13-10-2018 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 THITH_10010 f1a4a10364f9bb0a7c92312325c6adb8 257 Gene3D G3DSA:3.60.20.10 1 254 8.7E-70 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_10010 f1a4a10364f9bb0a7c92312325c6adb8 257 Pfam PF13230 Glutamine amidotransferases class-II 40 199 3.9E-11 T 13-10-2018 IPR026869 Putative glutamine amidotransferase type 2 THITH_10010 f1a4a10364f9bb0a7c92312325c6adb8 257 SUPERFAMILY SSF56235 34 249 3.09E-28 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_11505 a2254f3feb9c4d6189703b6338c49a12 659 Pfam PF12161 HsdM N-terminal domain 11 140 3.5E-22 T 13-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THITH_11505 a2254f3feb9c4d6189703b6338c49a12 659 Gene3D G3DSA:3.40.50.150 154 463 1.9E-91 T 13-10-2018 THITH_11505 a2254f3feb9c4d6189703b6338c49a12 659 SUPERFAMILY SSF53335 8 534 6.83E-116 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_11505 a2254f3feb9c4d6189703b6338c49a12 659 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 279 291 3.5E-11 T 13-10-2018 THITH_11505 a2254f3feb9c4d6189703b6338c49a12 659 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 207 221 3.5E-11 T 13-10-2018 THITH_11505 a2254f3feb9c4d6189703b6338c49a12 659 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 175 191 3.5E-11 T 13-10-2018 THITH_11505 a2254f3feb9c4d6189703b6338c49a12 659 Pfam PF02384 N-6 DNA Methylase 155 450 1.2E-58 T 13-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THITH_00890 abce9c3996f68f5987d2554fe777fac4 120 Gene3D G3DSA:3.30.450.30 2 120 1.9E-28 T 13-10-2018 THITH_00890 abce9c3996f68f5987d2554fe777fac4 120 SMART SM00960 6 96 2.6E-23 T 13-10-2018 IPR004942 Roadblock/LAMTOR2 domain THITH_00890 abce9c3996f68f5987d2554fe777fac4 120 SUPERFAMILY SSF103196 4 118 1.53E-29 T 13-10-2018 THITH_00890 abce9c3996f68f5987d2554fe777fac4 120 Pfam PF03259 Roadblock/LC7 domain 16 95 3.0E-16 T 13-10-2018 IPR004942 Roadblock/LAMTOR2 domain THITH_05610 7f00e2bd41378a163a4046a3387bb6e3 111 SUPERFAMILY SSF143100 3 67 7.32E-9 T 13-10-2018 IPR035069 TTHA1013/TTHA0281-like THITH_05610 7f00e2bd41378a163a4046a3387bb6e3 111 SUPERFAMILY SSF47598 70 105 1.56E-7 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 THITH_05610 7f00e2bd41378a163a4046a3387bb6e3 111 Pfam PF05534 HicB family 57 105 7.4E-18 T 13-10-2018 IPR008651 Uncharacterised protein family HicB THITH_13030 caa4106d216bdd8f3ff1d26a82403bd5 101 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 3 96 7.0E-26 T 13-10-2018 IPR017924 RNA-binding protein YhbY GO:0003723 THITH_13030 caa4106d216bdd8f3ff1d26a82403bd5 101 Gene3D G3DSA:3.30.110.60 1 97 7.0E-32 T 13-10-2018 IPR035920 YhbY-like superfamily THITH_13030 caa4106d216bdd8f3ff1d26a82403bd5 101 SMART SM01103 3 86 2.2E-39 T 13-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 THITH_13030 caa4106d216bdd8f3ff1d26a82403bd5 101 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 9 90 1.0E-18 T 13-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 THITH_13030 caa4106d216bdd8f3ff1d26a82403bd5 101 Pfam PF01985 CRS1 / YhbY (CRM) domain 3 86 5.2E-23 T 13-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 THITH_13030 caa4106d216bdd8f3ff1d26a82403bd5 101 SUPERFAMILY SSF75471 2 94 2.88E-29 T 13-10-2018 IPR035920 YhbY-like superfamily THITH_08575 6cce80f6ede570ae449d80ec0d3ff1ae 289 Pfam PF05726 Pirin C-terminal cupin domain 182 283 1.2E-28 T 13-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 THITH_08575 6cce80f6ede570ae449d80ec0d3ff1ae 289 SUPERFAMILY SSF51182 10 286 1.02E-83 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily THITH_08575 6cce80f6ede570ae449d80ec0d3ff1ae 289 PIRSF PIRSF006232 2 288 9.7E-89 T 13-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 THITH_08575 6cce80f6ede570ae449d80ec0d3ff1ae 289 Gene3D G3DSA:2.60.120.10 149 252 3.3E-82 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_08575 6cce80f6ede570ae449d80ec0d3ff1ae 289 Pfam PF02678 Pirin 20 127 1.0E-31 T 13-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 THITH_08575 6cce80f6ede570ae449d80ec0d3ff1ae 289 Gene3D G3DSA:2.60.120.10 17 278 3.3E-82 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_06465 c6e7766026106388a122bc357842b4de 372 Pfam PF17179 4Fe-4S dicluster domain 261 355 1.2E-30 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_06465 c6e7766026106388a122bc357842b4de 372 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 262 273 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_06465 c6e7766026106388a122bc357842b4de 372 SUPERFAMILY SSF46548 246 359 1.13E-14 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_06465 c6e7766026106388a122bc357842b4de 372 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 341 352 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 SMART SM00267 273 445 7.1E-68 T 13-10-2018 IPR000160 GGDEF domain THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 Gene3D G3DSA:3.30.450.20 144 278 1.3E-20 T 13-10-2018 THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 Pfam PF08448 PAS fold 157 273 4.1E-11 T 13-10-2018 IPR013656 PAS fold-4 THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 SUPERFAMILY SSF52172 14 166 6.97E-38 T 13-10-2018 IPR011006 CheY-like superfamily THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 Pfam PF00990 Diguanylate cyclase, GGDEF domain 284 440 8.8E-53 T 13-10-2018 IPR000160 GGDEF domain THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 148 278 3.9E-16 T 13-10-2018 IPR000014 PAS domain THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 Gene3D G3DSA:3.40.50.2300 2 143 9.1E-34 T 13-10-2018 THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 Pfam PF00072 Response regulator receiver domain 17 127 3.6E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 SMART SM00448 15 126 2.1E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 SUPERFAMILY SSF141868 459 703 3.53E-78 T 13-10-2018 IPR035919 EAL domain superfamily THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 Pfam PF00563 EAL domain 460 695 2.2E-68 T 13-10-2018 IPR001633 EAL domain THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 SUPERFAMILY SSF55785 139 271 5.86E-18 T 13-10-2018 IPR035965 PAS domain superfamily THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 282 444 1.7E-43 T 13-10-2018 IPR000160 GGDEF domain THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 SUPERFAMILY SSF55073 289 446 6.8E-53 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 Gene3D G3DSA:3.20.20.450 458 705 7.8E-90 T 13-10-2018 IPR035919 EAL domain superfamily THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 Gene3D G3DSA:3.30.70.270 279 457 1.5E-63 T 13-10-2018 THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 SMART SM00091 151 217 1.8E-12 T 13-10-2018 IPR000014 PAS domain THITH_07855 b8985521d2553f70a8d18bdf3fbdfeb5 719 SMART SM00052 454 700 2.0E-96 T 13-10-2018 IPR001633 EAL domain THITH_12795 acc11444a9d9f6a3470345b0e55a6598 486 SMART SM01240 6 472 0.0 T 13-10-2018 THITH_12795 acc11444a9d9f6a3470345b0e55a6598 486 SUPERFAMILY SSF51412 3 476 4.06E-126 T 13-10-2018 THITH_12795 acc11444a9d9f6a3470345b0e55a6598 486 PIRSF PIRSF000130 1 486 4.7E-206 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 THITH_12795 acc11444a9d9f6a3470345b0e55a6598 486 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 293 305 - T 13-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 THITH_12795 acc11444a9d9f6a3470345b0e55a6598 486 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 7 472 6.8E-164 T 13-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 THITH_12795 acc11444a9d9f6a3470345b0e55a6598 486 SUPERFAMILY SSF54631 93 201 6.06E-28 T 13-10-2018 THITH_12795 acc11444a9d9f6a3470345b0e55a6598 486 SMART SM00116 95 142 4.8E-9 T 13-10-2018 IPR000644 CBS domain THITH_12795 acc11444a9d9f6a3470345b0e55a6598 486 SMART SM00116 156 204 2.3E-8 T 13-10-2018 IPR000644 CBS domain THITH_12795 acc11444a9d9f6a3470345b0e55a6598 486 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 7 485 85.178 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 THITH_12795 acc11444a9d9f6a3470345b0e55a6598 486 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 7 453 8.4E-195 T 13-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 THITH_12795 acc11444a9d9f6a3470345b0e55a6598 486 Gene3D G3DSA:3.20.20.70 1 485 5.4E-214 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_12795 acc11444a9d9f6a3470345b0e55a6598 486 Pfam PF00571 CBS domain 94 138 1.7E-9 T 13-10-2018 IPR000644 CBS domain THITH_12795 acc11444a9d9f6a3470345b0e55a6598 486 Pfam PF00571 CBS domain 147 199 3.1E-6 T 13-10-2018 IPR000644 CBS domain THITH_07110 b940987e097eb8c55c852a6bdfb76a72 159 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 155 1.2E-65 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THITH_07110 b940987e097eb8c55c852a6bdfb76a72 159 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 13-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THITH_07110 b940987e097eb8c55c852a6bdfb76a72 159 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 156 35.329 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THITH_07110 b940987e097eb8c55c852a6bdfb76a72 159 Gene3D G3DSA:3.30.1330.50 1 159 2.9E-69 T 13-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THITH_07110 b940987e097eb8c55c852a6bdfb76a72 159 SUPERFAMILY SSF69765 1 156 4.19E-64 T 13-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THITH_07110 b940987e097eb8c55c852a6bdfb76a72 159 Pfam PF02542 YgbB family 2 154 1.7E-64 T 13-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 THITH_07460 914f21cabdcb5a70ecb9a541e6cd458f 449 Gene3D G3DSA:3.40.50.720 212 374 7.0E-164 T 13-10-2018 THITH_07460 914f21cabdcb5a70ecb9a541e6cd458f 449 Gene3D G3DSA:1.10.285.10 391 449 6.1E-6 T 13-10-2018 THITH_07460 914f21cabdcb5a70ecb9a541e6cd458f 449 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 124 137 - T 13-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 THITH_07460 914f21cabdcb5a70ecb9a541e6cd458f 449 SUPERFAMILY SSF51735 205 448 6.93E-76 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_07460 914f21cabdcb5a70ecb9a541e6cd458f 449 Gene3D G3DSA:1.10.285.10 10 385 7.0E-164 T 13-10-2018 THITH_07460 914f21cabdcb5a70ecb9a541e6cd458f 449 SUPERFAMILY SSF53223 10 199 7.04E-72 T 13-10-2018 THITH_07460 914f21cabdcb5a70ecb9a541e6cd458f 449 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 205 447 7.2E-86 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 THITH_07460 914f21cabdcb5a70ecb9a541e6cd458f 449 SMART SM00839 207 447 5.0E-84 T 13-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 THITH_07460 914f21cabdcb5a70ecb9a541e6cd458f 449 Gene3D G3DSA:3.40.50.10860 57 192 7.0E-164 T 13-10-2018 THITH_07460 914f21cabdcb5a70ecb9a541e6cd458f 449 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 373 384 1.3E-28 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 THITH_07460 914f21cabdcb5a70ecb9a541e6cd458f 449 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 116 130 1.3E-28 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 THITH_07460 914f21cabdcb5a70ecb9a541e6cd458f 449 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 196 218 1.3E-28 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 THITH_07460 914f21cabdcb5a70ecb9a541e6cd458f 449 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 238 258 1.3E-28 T 13-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 THITH_07460 914f21cabdcb5a70ecb9a541e6cd458f 449 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 59 187 1.5E-47 T 13-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 THITH_07460 914f21cabdcb5a70ecb9a541e6cd458f 449 PIRSF PIRSF000185 24 449 1.1E-111 T 13-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 THITH_02310 dd1175d7308e7bb329ab00497b5d7cb1 170 Pfam PF00578 AhpC/TSA family 40 149 2.4E-17 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THITH_02310 dd1175d7308e7bb329ab00497b5d7cb1 170 SUPERFAMILY SSF52833 38 157 6.43E-30 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_02310 dd1175d7308e7bb329ab00497b5d7cb1 170 Gene3D G3DSA:3.40.30.10 30 164 1.2E-29 T 13-10-2018 THITH_11210 b9a45e0e3298d77df551fbf4a6066afa 241 SUPERFAMILY SSF56349 9 203 1.71E-27 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THITH_11210 b9a45e0e3298d77df551fbf4a6066afa 241 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 4 82 2.0E-20 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THITH_11210 b9a45e0e3298d77df551fbf4a6066afa 241 Gene3D G3DSA:1.10.443.10 94 229 2.1E-27 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 THITH_11210 b9a45e0e3298d77df551fbf4a6066afa 241 Pfam PF00589 Phage integrase family 103 180 1.3E-15 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THITH_11210 b9a45e0e3298d77df551fbf4a6066afa 241 Gene3D G3DSA:1.10.150.130 2 87 9.4E-17 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal THITH_03820 6823cd05a09dd10046cd774009d4e45a 380 Pfam PF03739 Predicted permease YjgP/YjgQ family 21 364 2.3E-64 T 13-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 THITH_03820 6823cd05a09dd10046cd774009d4e45a 380 TIGRFAM TIGR04407 LptF_YjgP: LPS export ABC transporter permease LptF 18 363 3.1E-95 T 13-10-2018 IPR030922 LPS export ABC transporter permease LptF GO:0043190|GO:0055085 THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 SUPERFAMILY SSF50447 271 410 1.3E-35 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 13-10-2018 IPR031157 Tr-type G domain, conserved site THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 SUPERFAMILY SSF52540 6 288 4.74E-110 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 SMART SM00838 606 693 1.4E-56 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 Pfam PF14492 Elongation Factor G, domain II 410 484 3.2E-35 T 13-10-2018 THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 Gene3D G3DSA:3.40.50.300 1 299 3.4E-117 T 13-10-2018 THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 TIGRFAM TIGR00484 EF-G: translation elongation factor G 2 697 0.0 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 SUPERFAMILY SSF54211 485 604 9.86E-47 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 PRINTS PR00315 GTP-binding elongation factor signature 101 112 1.7E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 PRINTS PR00315 GTP-binding elongation factor signature 137 146 1.7E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 PRINTS PR00315 GTP-binding elongation factor signature 85 95 1.7E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 PRINTS PR00315 GTP-binding elongation factor signature 12 25 1.7E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 PRINTS PR00315 GTP-binding elongation factor signature 58 66 1.7E-15 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 Pfam PF03764 Elongation factor G, domain IV 485 603 3.7E-49 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 SUPERFAMILY SSF54980 410 487 8.27E-26 T 13-10-2018 IPR035647 EF-G domain III/V-like THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 Hamap MF_00054_B Elongation factor G [fusA]. 6 697 114.38 T 13-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 Pfam PF00679 Elongation factor G C-terminus 606 691 5.3E-31 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 SUPERFAMILY SSF54980 606 696 2.83E-30 T 13-10-2018 IPR035647 EF-G domain III/V-like THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 Gene3D G3DSA:3.30.70.870 412 489 2.6E-34 T 13-10-2018 THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 10 187 4.0E-34 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 SMART SM00889 486 604 2.3E-76 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 Gene3D G3DSA:2.40.30.10 300 411 4.7E-43 T 13-10-2018 THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 Pfam PF03144 Elongation factor Tu domain 2 330 397 7.2E-16 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 Pfam PF00009 Elongation factor Tu GTP binding domain 8 288 6.1E-67 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 Gene3D G3DSA:3.30.230.10 490 693 1.6E-93 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THITH_14305 abfe6816d49f1fc07c2ecbb8089fa9b3 698 Gene3D G3DSA:3.30.70.240 610 680 1.6E-93 T 13-10-2018 THITH_17070 b210b7392e3d26277cc0cd0d02c99dbe 387 SUPERFAMILY SSF51261 183 383 2.35E-37 T 13-10-2018 IPR011055 Duplicated hybrid motif THITH_17070 b210b7392e3d26277cc0cd0d02c99dbe 387 Pfam PF01551 Peptidase family M23 288 380 3.4E-22 T 13-10-2018 IPR016047 Peptidase M23 THITH_17070 b210b7392e3d26277cc0cd0d02c99dbe 387 Gene3D G3DSA:2.70.70.10 247 385 6.3E-29 T 13-10-2018 IPR011055 Duplicated hybrid motif THITH_03060 31151ac1951d9147981e959aaa864a7a 264 PIRSF PIRSF004846 5 259 4.2E-62 T 13-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 THITH_03060 31151ac1951d9147981e959aaa864a7a 264 Gene3D G3DSA:3.40.190.10 36 255 3.5E-68 T 13-10-2018 THITH_03060 31151ac1951d9147981e959aaa864a7a 264 SUPERFAMILY SSF53850 31 258 1.84E-53 T 13-10-2018 THITH_03060 31151ac1951d9147981e959aaa864a7a 264 Pfam PF13531 Bacterial extracellular solute-binding protein 33 255 4.1E-46 T 13-10-2018 THITH_03060 31151ac1951d9147981e959aaa864a7a 264 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 37 254 6.1E-55 T 13-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 THITH_03060 31151ac1951d9147981e959aaa864a7a 264 Gene3D G3DSA:3.40.190.10 111 217 3.5E-68 T 13-10-2018 THITH_07955 1e2d19f261b7405f3164a1667ddc5845 293 Pfam PF02153 Prephenate dehydrogenase 17 273 1.6E-74 T 13-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 THITH_07955 1e2d19f261b7405f3164a1667ddc5845 293 Gene3D G3DSA:3.40.50.720 2 181 3.1E-55 T 13-10-2018 THITH_07955 1e2d19f261b7405f3164a1667ddc5845 293 SUPERFAMILY SSF48179 175 283 2.49E-35 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THITH_07955 1e2d19f261b7405f3164a1667ddc5845 293 SUPERFAMILY SSF51735 4 171 2.38E-48 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_07955 1e2d19f261b7405f3164a1667ddc5845 293 Gene3D G3DSA:1.10.3660.10 182 293 2.3E-37 T 13-10-2018 THITH_17435 9417dc5590aae1495f170c4e2b846a42 333 SUPERFAMILY SSF53850 31 318 7.38E-61 T 13-10-2018 THITH_17435 9417dc5590aae1495f170c4e2b846a42 333 Pfam PF16868 NMT1-like family 37 317 4.0E-75 T 13-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family THITH_17435 9417dc5590aae1495f170c4e2b846a42 333 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 9 317 1.1E-53 T 13-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family THITH_17435 9417dc5590aae1495f170c4e2b846a42 333 Gene3D G3DSA:3.40.190.10 37 317 1.7E-70 T 13-10-2018 THITH_17435 9417dc5590aae1495f170c4e2b846a42 333 Gene3D G3DSA:3.40.190.10 121 254 1.7E-70 T 13-10-2018 THITH_12165 3ec16153180458047c6003de9a7211a8 156 PIRSF PIRSF004923 4 152 2.8E-31 T 13-10-2018 IPR026268 Protein RseC THITH_12165 3ec16153180458047c6003de9a7211a8 156 Pfam PF04246 Positive regulator of sigma(E), RseC/MucC 11 143 2.0E-27 T 13-10-2018 THITH_09975 73e6b33f37997e55c90ed7c08d91723f 493 TIGRFAM TIGR00785 dass: transporter, divalent anion:Na+ symporter (DASS) family 38 486 6.1E-82 T 13-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 THITH_09975 73e6b33f37997e55c90ed7c08d91723f 493 ProSitePatterns PS01271 Sodium:sulfate symporter family signature. 436 452 - T 13-10-2018 IPR031312 Sodium/sulphate symporter, conserved site Reactome: R-HSA-433137 THITH_09975 73e6b33f37997e55c90ed7c08d91723f 493 Pfam PF00939 Sodium:sulfate symporter transmembrane region 29 488 3.2E-72 T 13-10-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 THITH_06100 2aaff36a83a1d50723cf6e27d3b7f867 1280 Pfam PF02754 Cysteine-rich domain 1020 1108 2.4E-5 T 13-10-2018 IPR004017 Cysteine-rich domain THITH_06100 2aaff36a83a1d50723cf6e27d3b7f867 1280 Pfam PF02754 Cysteine-rich domain 1145 1233 0.0016 T 13-10-2018 IPR004017 Cysteine-rich domain THITH_06100 2aaff36a83a1d50723cf6e27d3b7f867 1280 Gene3D G3DSA:3.30.465.40 127 323 3.4E-35 T 13-10-2018 THITH_06100 2aaff36a83a1d50723cf6e27d3b7f867 1280 Pfam PF12447 Protein of unknown function (DUF3683) 5 116 1.4E-47 T 13-10-2018 IPR022153 Protein of unknown function DUF3683 THITH_06100 2aaff36a83a1d50723cf6e27d3b7f867 1280 Gene3D G3DSA:3.30.70.2740 664 737 5.2E-7 T 13-10-2018 THITH_06100 2aaff36a83a1d50723cf6e27d3b7f867 1280 SUPERFAMILY SSF55103 665 776 8.34E-28 T 13-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 THITH_06100 2aaff36a83a1d50723cf6e27d3b7f867 1280 SUPERFAMILY SSF56176 127 395 1.43E-51 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 THITH_06100 2aaff36a83a1d50723cf6e27d3b7f867 1280 Pfam PF01565 FAD binding domain 166 309 1.1E-24 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THITH_06100 2aaff36a83a1d50723cf6e27d3b7f867 1280 Pfam PF02913 FAD linked oxidases, C-terminal domain 673 773 3.8E-20 T 13-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 THITH_06100 2aaff36a83a1d50723cf6e27d3b7f867 1280 Pfam PF02913 FAD linked oxidases, C-terminal domain 409 545 3.2E-7 T 13-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 THITH_06100 2aaff36a83a1d50723cf6e27d3b7f867 1280 SUPERFAMILY SSF55103 427 547 5.56E-14 T 13-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 THITH_06100 2aaff36a83a1d50723cf6e27d3b7f867 1280 SUPERFAMILY SSF46548 803 902 7.85E-13 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_06100 2aaff36a83a1d50723cf6e27d3b7f867 1280 Pfam PF13183 4Fe-4S dicluster domain 809 888 4.6E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_06100 2aaff36a83a1d50723cf6e27d3b7f867 1280 Pfam PF11880 Domain of unknown function (DUF3400) 1236 1280 2.1E-22 T 13-10-2018 IPR021817 Protein of unknown function DUF3400 THITH_11345 8041776b126a2b3a1eb57ed954ff4101 118 SMART SM00450 2 107 5.7E-20 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_11345 8041776b126a2b3a1eb57ed954ff4101 118 Gene3D G3DSA:3.40.250.10 1 111 3.0E-27 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_11345 8041776b126a2b3a1eb57ed954ff4101 118 SUPERFAMILY SSF52821 1 112 2.23E-28 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_11345 8041776b126a2b3a1eb57ed954ff4101 118 Pfam PF00581 Rhodanese-like domain 2 103 2.3E-13 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 617 633 7.7E-19 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 677 702 7.7E-19 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 645 661 7.7E-19 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 499 517 7.7E-19 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 SMART SM00831 17 90 1.2E-32 T 13-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 564 574 2.4E-41 T 13-10-2018 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 645 664 2.4E-41 T 13-10-2018 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 175 189 2.4E-41 T 13-10-2018 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 338 352 2.4E-41 T 13-10-2018 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 542 553 2.4E-41 T 13-10-2018 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 669 681 2.4E-41 T 13-10-2018 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 Pfam PF00122 E1-E2 ATPase 125 318 3.5E-53 T 13-10-2018 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 Pfam PF00690 Cation transporter/ATPase, N-terminus 18 83 3.0E-15 T 13-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 340 346 - T 13-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 220 355 7.0E-23 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 612 735 3.1E-34 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 96 202 2.8E-20 T 13-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 Pfam PF00689 Cation transporting ATPase, C-terminus 730 902 8.3E-44 T 13-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 SUPERFAMILY SSF56784 336 750 1.13E-62 T 13-10-2018 IPR036412 HAD-like superfamily THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 SUPERFAMILY SSF81660 345 534 3.92E-51 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 Gene3D G3DSA:1.20.1110.10 68 901 1.1E-291 T 13-10-2018 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 Gene3D G3DSA:3.40.50.1000 335 690 1.1E-291 T 13-10-2018 IPR023214 HAD superfamily THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 SUPERFAMILY SSF81653 127 236 6.02E-30 T 13-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 Pfam PF08282 haloacid dehalogenase-like hydrolase 639 691 1.1E-5 T 13-10-2018 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 Gene3D G3DSA:2.70.150.10 33 240 1.1E-291 T 13-10-2018 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 Gene3D G3DSA:3.40.1110.10 348 549 1.1E-291 T 13-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 SUPERFAMILY SSF81665 18 907 1.96E-126 T 13-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 THITH_15480 e2cfefccd152132932849eaa9174e5e9 913 Pfam PF13246 Cation transport ATPase (P-type) 399 484 3.4E-21 T 13-10-2018 THITH_03520 b7fa98d13004845eab5d8767b07b4cb1 431 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 6 429 1.2E-184 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THITH_03520 b7fa98d13004845eab5d8767b07b4cb1 431 Gene3D G3DSA:3.40.440.10 6 249 4.0E-98 T 13-10-2018 THITH_03520 b7fa98d13004845eab5d8767b07b4cb1 431 SUPERFAMILY SSF52540 4 429 4.57E-177 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_03520 b7fa98d13004845eab5d8767b07b4cb1 431 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 11 18 - T 13-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THITH_03520 b7fa98d13004845eab5d8767b07b4cb1 431 Gene3D G3DSA:1.10.300.10 102 201 4.0E-98 T 13-10-2018 THITH_03520 b7fa98d13004845eab5d8767b07b4cb1 431 Pfam PF00709 Adenylosuccinate synthetase 5 423 3.5E-179 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THITH_03520 b7fa98d13004845eab5d8767b07b4cb1 431 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 133 144 - T 13-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THITH_03520 b7fa98d13004845eab5d8767b07b4cb1 431 SMART SM00788 4 424 1.1E-298 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THITH_03520 b7fa98d13004845eab5d8767b07b4cb1 431 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 431 214.569 T 13-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 THITH_03520 b7fa98d13004845eab5d8767b07b4cb1 431 Gene3D G3DSA:3.90.170.10 267 431 2.0E-70 T 13-10-2018 THITH_02375 cccf856d90ddba3f56d65855b6a1b306 232 SMART SM00862 145 220 1.5E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THITH_02375 cccf856d90ddba3f56d65855b6a1b306 232 Gene3D G3DSA:3.40.50.2300 1 121 1.7E-37 T 13-10-2018 THITH_02375 cccf856d90ddba3f56d65855b6a1b306 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 220 1.8E-20 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THITH_02375 cccf856d90ddba3f56d65855b6a1b306 232 Gene3D G3DSA:1.10.10.10 122 229 6.1E-27 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_02375 cccf856d90ddba3f56d65855b6a1b306 232 SUPERFAMILY SSF52172 2 127 1.14E-38 T 13-10-2018 IPR011006 CheY-like superfamily THITH_02375 cccf856d90ddba3f56d65855b6a1b306 232 SUPERFAMILY SSF46894 119 221 1.84E-25 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THITH_02375 cccf856d90ddba3f56d65855b6a1b306 232 Pfam PF00072 Response regulator receiver domain 3 112 1.6E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_02375 cccf856d90ddba3f56d65855b6a1b306 232 SMART SM00448 1 112 1.1E-38 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_05955 81989683b124dfcb506d396022fc6a90 106 Pfam PF01381 Helix-turn-helix 51 94 7.1E-9 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_05955 81989683b124dfcb506d396022fc6a90 106 SMART SM00530 50 104 3.4E-4 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_05955 81989683b124dfcb506d396022fc6a90 106 SUPERFAMILY SSF47413 49 99 1.57E-10 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 THITH_05955 81989683b124dfcb506d396022fc6a90 106 Gene3D G3DSA:1.10.260.40 5 103 2.2E-18 T 13-10-2018 THITH_15595 3299261bff7ecadc41617bf34ef7fb0b 389 Gene3D G3DSA:3.40.50.450 2 306 4.9E-104 T 13-10-2018 THITH_15595 3299261bff7ecadc41617bf34ef7fb0b 389 SUPERFAMILY SSF102405 96 303 4.58E-45 T 13-10-2018 THITH_15595 3299261bff7ecadc41617bf34ef7fb0b 389 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 91 303 6.0E-72 T 13-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 THITH_15595 3299261bff7ecadc41617bf34ef7fb0b 389 Pfam PF02481 DNA recombination-mediator protein A 92 294 2.4E-72 T 13-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 THITH_15595 3299261bff7ecadc41617bf34ef7fb0b 389 Gene3D G3DSA:1.10.10.10 307 380 3.8E-10 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_00795 10e0fb03ee84548370737861b5a366ed 78 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 4 75 1.2E-17 T 13-10-2018 IPR014295 Anti-sigma factor THITH_00795 10e0fb03ee84548370737861b5a366ed 78 Pfam PF13490 Putative zinc-finger 8 41 9.5E-10 T 13-10-2018 IPR027383 Putative zinc-finger THITH_06360 2cdd66912e828dedafd060b84558cf71 250 Gene3D G3DSA:3.60.15.10 1 238 5.9E-74 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_06360 2cdd66912e828dedafd060b84558cf71 250 SUPERFAMILY SSF56281 1 227 1.4E-53 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_06360 2cdd66912e828dedafd060b84558cf71 250 Pfam PF00753 Metallo-beta-lactamase superfamily 12 175 2.4E-19 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_06360 2cdd66912e828dedafd060b84558cf71 250 SMART SM00849 12 175 1.8E-27 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_03000 3b67e3d9fabd5d3aac4c10e49e5ec0cc 435 SUPERFAMILY SSF52821 336 421 6.16E-20 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_03000 3b67e3d9fabd5d3aac4c10e49e5ec0cc 435 SUPERFAMILY SSF52821 209 323 2.88E-19 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_03000 3b67e3d9fabd5d3aac4c10e49e5ec0cc 435 Gene3D G3DSA:3.40.250.10 211 332 4.1E-17 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_03000 3b67e3d9fabd5d3aac4c10e49e5ec0cc 435 SUPERFAMILY SSF52821 94 206 2.88E-18 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_03000 3b67e3d9fabd5d3aac4c10e49e5ec0cc 435 SMART SM00450 104 205 6.1E-9 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_03000 3b67e3d9fabd5d3aac4c10e49e5ec0cc 435 SMART SM00450 339 429 1.2E-10 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_03000 3b67e3d9fabd5d3aac4c10e49e5ec0cc 435 SMART SM00450 208 317 5.1E-9 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_03000 3b67e3d9fabd5d3aac4c10e49e5ec0cc 435 Gene3D G3DSA:3.40.250.10 335 431 3.8E-19 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_03000 3b67e3d9fabd5d3aac4c10e49e5ec0cc 435 Gene3D G3DSA:3.40.250.10 100 209 2.8E-16 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_03000 3b67e3d9fabd5d3aac4c10e49e5ec0cc 435 Pfam PF00581 Rhodanese-like domain 108 201 1.7E-7 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_03000 3b67e3d9fabd5d3aac4c10e49e5ec0cc 435 Pfam PF00581 Rhodanese-like domain 210 314 2.6E-10 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_03000 3b67e3d9fabd5d3aac4c10e49e5ec0cc 435 Pfam PF00581 Rhodanese-like domain 341 422 3.7E-8 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_06345 f6666dac064ebdbefd0dd02409592901 323 PIRSF PIRSF005963 1 322 9.9E-134 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 THITH_06345 f6666dac064ebdbefd0dd02409592901 323 SUPERFAMILY SSF102114 49 312 4.71E-71 T 13-10-2018 THITH_06345 f6666dac064ebdbefd0dd02409592901 323 TIGRFAM TIGR00510 lipA: lipoyl synthase 27 312 1.6E-133 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 THITH_06345 f6666dac064ebdbefd0dd02409592901 323 Hamap MF_00206 Lipoyl synthase [lipA]. 1 320 159.308 T 13-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 THITH_06345 f6666dac064ebdbefd0dd02409592901 323 Pfam PF04055 Radical SAM superfamily 88 249 9.5E-18 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THITH_06345 f6666dac064ebdbefd0dd02409592901 323 SMART SM00729 81 290 7.7E-19 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THITH_06345 f6666dac064ebdbefd0dd02409592901 323 Gene3D G3DSA:3.20.20.70 79 281 5.4E-23 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_01680 d9db97d812ad43dbc1c7f8122cc40a42 292 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 220 286 7.7E-9 T 13-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal THITH_01680 d9db97d812ad43dbc1c7f8122cc40a42 292 Gene3D G3DSA:3.40.50.300 1 193 5.2E-55 T 13-10-2018 THITH_01680 d9db97d812ad43dbc1c7f8122cc40a42 292 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 2 176 6.3E-44 T 13-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain THITH_01680 d9db97d812ad43dbc1c7f8122cc40a42 292 SUPERFAMILY SSF52540 2 182 1.82E-30 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01680 d9db97d812ad43dbc1c7f8122cc40a42 292 SUPERFAMILY SSF90002 221 286 1.57E-7 T 13-10-2018 THITH_14975 9ea4de69181b141bbebaef744b1ec836 493 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 1 486 1.5E-138 T 13-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 THITH_14975 9ea4de69181b141bbebaef744b1ec836 493 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 250 432 1.9E-53 T 13-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 THITH_14975 9ea4de69181b141bbebaef744b1ec836 493 Pfam PF13500 AAA domain 1 229 1.8E-22 T 13-10-2018 THITH_14975 9ea4de69181b141bbebaef744b1ec836 493 Gene3D G3DSA:3.40.50.880 255 389 1.7E-12 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_14975 9ea4de69181b141bbebaef744b1ec836 493 SUPERFAMILY SSF52540 1 234 4.09E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14975 9ea4de69181b141bbebaef744b1ec836 493 Gene3D G3DSA:3.40.50.300 1 233 1.8E-55 T 13-10-2018 THITH_14975 9ea4de69181b141bbebaef744b1ec836 493 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 493 201.093 T 13-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 THITH_14975 9ea4de69181b141bbebaef744b1ec836 493 SUPERFAMILY SSF52317 251 442 2.78E-34 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_03215 d6ac99512694ef4a97be9b9a255a5c01 152 SMART SM00116 10 62 2.4E-9 T 13-10-2018 IPR000644 CBS domain THITH_03215 d6ac99512694ef4a97be9b9a255a5c01 152 SMART SM00116 80 128 2.2E-8 T 13-10-2018 IPR000644 CBS domain THITH_03215 d6ac99512694ef4a97be9b9a255a5c01 152 Pfam PF00571 CBS domain 74 128 1.4E-10 T 13-10-2018 IPR000644 CBS domain THITH_03215 d6ac99512694ef4a97be9b9a255a5c01 152 Pfam PF00571 CBS domain 3 61 6.6E-12 T 13-10-2018 IPR000644 CBS domain THITH_03215 d6ac99512694ef4a97be9b9a255a5c01 152 SUPERFAMILY SSF54631 1 141 1.39E-29 T 13-10-2018 THITH_03215 d6ac99512694ef4a97be9b9a255a5c01 152 Gene3D G3DSA:3.10.580.10 1 149 6.0E-32 T 13-10-2018 THITH_13675 32f27a54bfeb6d78dd6319cbdc36505b 322 Gene3D G3DSA:1.10.10.10 1 64 8.0E-8 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_13675 32f27a54bfeb6d78dd6319cbdc36505b 322 Pfam PF08279 HTH domain 6 62 1.1E-6 T 13-10-2018 IPR013196 Helix-turn-helix, type 11 THITH_13675 32f27a54bfeb6d78dd6319cbdc36505b 322 Pfam PF13280 WYL domain 144 316 6.9E-40 T 13-10-2018 IPR026881 WYL domain THITH_08580 47f8d398008f7466a6604a8c1e152859 208 Gene3D G3DSA:3.40.50.850 1 208 7.6E-59 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 THITH_08580 47f8d398008f7466a6604a8c1e152859 208 Pfam PF00857 Isochorismatase family 14 165 5.6E-22 T 13-10-2018 IPR000868 Isochorismatase-like GO:0003824 THITH_08580 47f8d398008f7466a6604a8c1e152859 208 SUPERFAMILY SSF52499 3 202 1.02E-53 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 THITH_08735 0c534fd4a174cd9f0331ab4625661507 412 PIRSF PIRSF000447 1 412 2.4E-184 T 13-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 THITH_08735 0c534fd4a174cd9f0331ab4625661507 412 Gene3D G3DSA:3.40.47.10 257 401 6.6E-51 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 THITH_08735 0c534fd4a174cd9f0331ab4625661507 412 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 255 369 4.0E-36 T 13-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal THITH_08735 0c534fd4a174cd9f0331ab4625661507 412 SUPERFAMILY SSF53901 4 252 1.01E-76 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 THITH_08735 0c534fd4a174cd9f0331ab4625661507 412 Gene3D G3DSA:3.40.47.10 1 255 1.4E-90 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 THITH_08735 0c534fd4a174cd9f0331ab4625661507 412 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 13-10-2018 IPR018201 Beta-ketoacyl synthase, active site THITH_08735 0c534fd4a174cd9f0331ab4625661507 412 SMART SM00825 Beta-ketoacyl synthase 6 409 1.7E-13 T 13-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain THITH_08735 0c534fd4a174cd9f0331ab4625661507 412 SUPERFAMILY SSF53901 214 410 9.61E-72 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 THITH_08735 0c534fd4a174cd9f0331ab4625661507 412 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 410 2.0E-192 T 13-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 THITH_08735 0c534fd4a174cd9f0331ab4625661507 412 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 247 3.6E-60 T 13-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal THITH_14690 e2e519e1a8bd67b29ba7846bdd3fac84 90 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 13-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site THITH_14690 e2e519e1a8bd67b29ba7846bdd3fac84 90 PRINTS PR00107 Phosphocarrier protein signature 13 29 4.5E-13 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like THITH_14690 e2e519e1a8bd67b29ba7846bdd3fac84 90 PRINTS PR00107 Phosphocarrier protein signature 38 53 4.5E-13 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like THITH_14690 e2e519e1a8bd67b29ba7846bdd3fac84 90 PRINTS PR00107 Phosphocarrier protein signature 53 70 4.5E-13 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like THITH_14690 e2e519e1a8bd67b29ba7846bdd3fac84 90 Gene3D G3DSA:3.30.1340.10 1 89 2.3E-29 T 13-10-2018 IPR035895 HPr-like superfamily THITH_14690 e2e519e1a8bd67b29ba7846bdd3fac84 90 SUPERFAMILY SSF55594 1 89 1.83E-26 T 13-10-2018 IPR035895 HPr-like superfamily THITH_14690 e2e519e1a8bd67b29ba7846bdd3fac84 90 Pfam PF00381 PTS HPr component phosphorylation site 4 83 8.5E-26 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like THITH_14690 e2e519e1a8bd67b29ba7846bdd3fac84 90 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 13-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site THITH_14690 e2e519e1a8bd67b29ba7846bdd3fac84 90 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 82 1.5E-27 T 13-10-2018 IPR000032 Phosphocarrier protein HPr-like THITH_04045 7097ef00f1d913a922a50b4ca43b3acf 90 SUPERFAMILY SSF52833 3 86 1.38E-23 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_04045 7097ef00f1d913a922a50b4ca43b3acf 90 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 4 84 1.3E-28 T 13-10-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 THITH_04045 7097ef00f1d913a922a50b4ca43b3acf 90 Pfam PF00462 Glutaredoxin 6 65 4.1E-18 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 THITH_04045 7097ef00f1d913a922a50b4ca43b3acf 90 Gene3D G3DSA:3.40.30.10 1 87 7.3E-24 T 13-10-2018 THITH_04045 7097ef00f1d913a922a50b4ca43b3acf 90 PRINTS PR00160 Glutaredoxin signature 62 75 1.6E-15 T 13-10-2018 IPR014025 Glutaredoxin subgroup THITH_04045 7097ef00f1d913a922a50b4ca43b3acf 90 PRINTS PR00160 Glutaredoxin signature 4 22 1.6E-15 T 13-10-2018 IPR014025 Glutaredoxin subgroup THITH_04045 7097ef00f1d913a922a50b4ca43b3acf 90 PRINTS PR00160 Glutaredoxin signature 48 61 1.6E-15 T 13-10-2018 IPR014025 Glutaredoxin subgroup THITH_04045 7097ef00f1d913a922a50b4ca43b3acf 90 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 13-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 THITH_00165 3ee2046ca02785299260a913e70f3704 202 Pfam PF12840 Helix-turn-helix domain 5 62 8.9E-8 T 13-10-2018 THITH_00165 3ee2046ca02785299260a913e70f3704 202 SUPERFAMILY SSF46785 6 74 2.61E-13 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_00165 3ee2046ca02785299260a913e70f3704 202 Gene3D G3DSA:1.10.10.10 3 115 1.3E-13 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_00165 3ee2046ca02785299260a913e70f3704 202 SMART SM00418 3 80 1.7E-4 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THITH_01720 cdfdbb329f1b348cc80b0f9aad84c452 233 SUPERFAMILY SSF52402 8 136 2.68E-5 T 13-10-2018 THITH_01720 cdfdbb329f1b348cc80b0f9aad84c452 233 Gene3D G3DSA:3.40.50.12370 9 141 2.5E-5 T 13-10-2018 THITH_09265 671b0166f170aeaba810ca1aba0e2464 503 TIGRFAM TIGR02549 CRISPR_DxTHG: CRISPR-associated DxTHG motif protein 106 124 4.1E-4 T 13-10-2018 IPR013383 CRISPR-associated protein DxTHG, conserved site THITH_09265 671b0166f170aeaba810ca1aba0e2464 503 Pfam PF09455 CRISPR-associated (Cas) DxTHG family 5 372 6.4E-40 T 13-10-2018 IPR019016 CRISPR-associated DxTHG protein THITH_09265 671b0166f170aeaba810ca1aba0e2464 503 Pfam PF09652 Putative CRISPR-associated protein (Cas_VVA1548) 410 498 2.4E-37 T 13-10-2018 IPR013443 Putative CRISPR-associated protein, VVA1548 family THITH_09265 671b0166f170aeaba810ca1aba0e2464 503 TIGRFAM TIGR02620 cas_VVA1548: putative CRISPR-associated protein, VVA1548 family 410 500 2.4E-31 T 13-10-2018 IPR013443 Putative CRISPR-associated protein, VVA1548 family THITH_15290 90c2344193bee7e334630b7561772e2f 442 Gene3D G3DSA:1.20.1600.10 32 428 8.0E-38 T 13-10-2018 THITH_15290 90c2344193bee7e334630b7561772e2f 442 SUPERFAMILY SSF56954 10 427 2.35E-42 T 13-10-2018 THITH_15290 90c2344193bee7e334630b7561772e2f 442 Pfam PF02321 Outer membrane efflux protein 247 416 4.3E-12 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 THITH_15290 90c2344193bee7e334630b7561772e2f 442 Pfam PF02321 Outer membrane efflux protein 38 223 6.0E-13 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 THITH_06615 c1c1c049bb452a99404a2dba7c82ed83 320 Gene3D G3DSA:3.40.50.720 16 317 8.4E-107 T 13-10-2018 THITH_06615 c1c1c049bb452a99404a2dba7c82ed83 320 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 225 241 - T 13-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site THITH_06615 c1c1c049bb452a99404a2dba7c82ed83 320 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 19 318 2.6E-24 T 13-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 THITH_06615 c1c1c049bb452a99404a2dba7c82ed83 320 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 108 288 1.6E-49 T 13-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 THITH_06615 c1c1c049bb452a99404a2dba7c82ed83 320 SUPERFAMILY SSF52283 15 137 2.65E-28 T 13-10-2018 THITH_06615 c1c1c049bb452a99404a2dba7c82ed83 320 SUPERFAMILY SSF51735 102 289 8.15E-48 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_06615 c1c1c049bb452a99404a2dba7c82ed83 320 Gene3D G3DSA:3.40.50.720 98 287 8.4E-107 T 13-10-2018 THITH_02490 ba29ab9bf797169d5bc00eae7bcd1212 484 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 9 474 95.132 T 13-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THITH_02490 ba29ab9bf797169d5bc00eae7bcd1212 484 ProSitePatterns PS00571 Amidases signature. 149 180 - T 13-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 THITH_02490 ba29ab9bf797169d5bc00eae7bcd1212 484 SUPERFAMILY SSF75304 5 480 8.63E-170 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THITH_02490 ba29ab9bf797169d5bc00eae7bcd1212 484 Gene3D G3DSA:3.90.1300.10 4 483 2.8E-208 T 13-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THITH_02490 ba29ab9bf797169d5bc00eae7bcd1212 484 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 13 474 1.5E-188 T 13-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THITH_02490 ba29ab9bf797169d5bc00eae7bcd1212 484 Pfam PF01425 Amidase 22 463 5.9E-166 T 13-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 THITH_11410 82da517aa915f6eb836adf6dbcbdc15c 362 SUPERFAMILY SSF101790 270 358 4.09E-23 T 13-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal THITH_11410 82da517aa915f6eb836adf6dbcbdc15c 362 Gene3D G3DSA:3.30.1360.120 8 231 3.1E-82 T 13-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 THITH_11410 82da517aa915f6eb836adf6dbcbdc15c 362 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 3 355 9.7E-120 T 13-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 THITH_11410 82da517aa915f6eb836adf6dbcbdc15c 362 SUPERFAMILY SSF103025 3 278 3.92E-92 T 13-10-2018 THITH_11410 82da517aa915f6eb836adf6dbcbdc15c 362 Gene3D G3DSA:3.30.70.1400 52 139 3.1E-82 T 13-10-2018 THITH_11410 82da517aa915f6eb836adf6dbcbdc15c 362 Gene3D G3DSA:4.10.1250.10 232 276 2.1E-25 T 13-10-2018 THITH_11410 82da517aa915f6eb836adf6dbcbdc15c 362 Gene3D G3DSA:2.40.30.110 279 362 2.0E-26 T 13-10-2018 THITH_11410 82da517aa915f6eb836adf6dbcbdc15c 362 Hamap MF_00259 Aminomethyltransferase [gcvT]. 2 356 42.205 T 13-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THITH_11410 82da517aa915f6eb836adf6dbcbdc15c 362 Pfam PF01571 Aminomethyltransferase folate-binding domain 8 254 2.2E-84 T 13-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain THITH_11410 82da517aa915f6eb836adf6dbcbdc15c 362 PIRSF PIRSF006487 1 361 1.1E-81 T 13-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 THITH_11410 82da517aa915f6eb836adf6dbcbdc15c 362 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 263 351 4.4E-21 T 13-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 THITH_11265 c98338a759a10e018860f25121dd2977 895 Pfam PF00128 Alpha amylase, catalytic domain 27 109 1.0E-12 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THITH_11265 c98338a759a10e018860f25121dd2977 895 SUPERFAMILY SSF51445 8 792 4.4E-135 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily THITH_11265 c98338a759a10e018860f25121dd2977 895 SMART SM00642 12 763 7.9E-6 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THITH_11265 c98338a759a10e018860f25121dd2977 895 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 6 879 1.8E-295 T 13-10-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 THITH_11265 c98338a759a10e018860f25121dd2977 895 Gene3D G3DSA:3.20.20.80 508 622 2.1E-7 T 13-10-2018 THITH_11265 c98338a759a10e018860f25121dd2977 895 Gene3D G3DSA:3.20.20.80 264 403 1.2E-36 T 13-10-2018 THITH_11265 c98338a759a10e018860f25121dd2977 895 Gene3D G3DSA:3.20.20.80 657 799 7.1E-35 T 13-10-2018 THITH_11265 c98338a759a10e018860f25121dd2977 895 Gene3D G3DSA:3.30.1590.10 96 189 7.4E-26 T 13-10-2018 THITH_11265 c98338a759a10e018860f25121dd2977 895 Gene3D G3DSA:3.20.20.80 9 95 2.5E-17 T 13-10-2018 THITH_01295 cbcb2d5c4c900286f636bde25d8366dc 356 SUPERFAMILY SSF52317 18 333 6.54E-70 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_01295 cbcb2d5c4c900286f636bde25d8366dc 356 Pfam PF04204 Homoserine O-succinyltransferase 2 335 1.3E-88 T 13-10-2018 IPR033752 MetA family THITH_01295 cbcb2d5c4c900286f636bde25d8366dc 356 Hamap MF_00295 Homoserine O-succinyltransferase [metAS]. 31 337 35.914 T 13-10-2018 IPR033752 MetA family THITH_01295 cbcb2d5c4c900286f636bde25d8366dc 356 Gene3D G3DSA:3.40.50.880 1 337 4.7E-91 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_01295 cbcb2d5c4c900286f636bde25d8366dc 356 PIRSF PIRSF000450 277 341 1.7 T 13-10-2018 IPR033752 MetA family THITH_01295 cbcb2d5c4c900286f636bde25d8366dc 356 PIRSF PIRSF000450 1 280 1.2E-56 T 13-10-2018 IPR033752 MetA family THITH_01295 cbcb2d5c4c900286f636bde25d8366dc 356 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 255 2.0E-90 T 13-10-2018 THITH_10720 857e17cbd027cd773590722845a528fa 158 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 129 2.6E-45 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type THITH_10720 857e17cbd027cd773590722845a528fa 158 Pfam PF02082 Transcriptional regulator 1 83 9.0E-29 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type THITH_10720 857e17cbd027cd773590722845a528fa 158 SUPERFAMILY SSF46785 2 133 1.37E-37 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_10720 857e17cbd027cd773590722845a528fa 158 TIGRFAM TIGR02010 IscR: iron-sulfur cluster assembly transcription factor IscR 1 132 2.3E-63 T 13-10-2018 IPR010242 Transcription factor HTH, IscR GO:0003690|GO:0003700|GO:0006355 THITH_10720 857e17cbd027cd773590722845a528fa 158 Gene3D G3DSA:1.10.10.10 1 144 6.4E-54 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_16120 2ea1aee9feb26ee2a7a88dff3a98a40f 131 Gene3D G3DSA:2.170.150.20 1 131 2.0E-59 T 13-10-2018 THITH_16120 2ea1aee9feb26ee2a7a88dff3a98a40f 131 Hamap MF_01400 Peptide methionine sulfoxide reductase MsrB [msrB]. 8 131 37.593 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 THITH_16120 2ea1aee9feb26ee2a7a88dff3a98a40f 131 SUPERFAMILY SSF51316 7 130 5.23E-58 T 13-10-2018 IPR011057 Mss4-like superfamily THITH_16120 2ea1aee9feb26ee2a7a88dff3a98a40f 131 Pfam PF01641 SelR domain 11 130 4.1E-53 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 THITH_16120 2ea1aee9feb26ee2a7a88dff3a98a40f 131 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 7 130 8.9E-55 T 13-10-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 THITH_06880 941301921687ff3b1f56cbdcc18eb7df 162 Pfam PF03918 Cytochrome C biogenesis protein 20 154 1.7E-48 T 13-10-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family THITH_06880 941301921687ff3b1f56cbdcc18eb7df 162 Gene3D G3DSA:1.10.8.640 27 113 1.1E-31 T 13-10-2018 IPR038297 CcmH/CycL/Ccl2/NrfF domain superfamily THITH_11860 22c21a3bc9aea8c456d75e9a492465af 156 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 68 121 3.0E-18 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 THITH_11860 22c21a3bc9aea8c456d75e9a492465af 156 SUPERFAMILY SSF141734 20 133 1.57E-48 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 THITH_11860 22c21a3bc9aea8c456d75e9a492465af 156 Gene3D G3DSA:3.10.20.400 15 109 1.7E-40 T 13-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 THITH_11860 22c21a3bc9aea8c456d75e9a492465af 156 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 45 118 4.1E-34 T 13-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 THITH_11860 22c21a3bc9aea8c456d75e9a492465af 156 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 19 122 31.589 T 13-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 THITH_12325 160e845bcf5a9d9d517efd7bd7d497b2 161 SUPERFAMILY SSF47240 7 147 3.87E-29 T 13-10-2018 IPR009078 Ferritin-like superfamily THITH_12325 160e845bcf5a9d9d517efd7bd7d497b2 161 Pfam PF00210 Ferritin-like domain 14 145 1.6E-19 T 13-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 THITH_12325 160e845bcf5a9d9d517efd7bd7d497b2 161 Gene3D G3DSA:1.20.1260.10 5 151 7.2E-35 T 13-10-2018 IPR012347 Ferritin-like THITH_12325 160e845bcf5a9d9d517efd7bd7d497b2 161 PRINTS PR00601 Bacterioferritin signature 47 67 1.4E-16 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THITH_12325 160e845bcf5a9d9d517efd7bd7d497b2 161 PRINTS PR00601 Bacterioferritin signature 26 46 1.4E-16 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THITH_12325 160e845bcf5a9d9d517efd7bd7d497b2 161 PRINTS PR00601 Bacterioferritin signature 110 130 1.4E-16 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THITH_12325 160e845bcf5a9d9d517efd7bd7d497b2 161 PRINTS PR00601 Bacterioferritin signature 6 25 1.4E-16 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THITH_12325 160e845bcf5a9d9d517efd7bd7d497b2 161 PRINTS PR00601 Bacterioferritin signature 68 88 1.4E-16 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THITH_12325 160e845bcf5a9d9d517efd7bd7d497b2 161 PIRSF PIRSF002560 4 150 4.2E-25 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THITH_06305 2c48ad741f8c092481b1e87c4ea323b4 627 Gene3D G3DSA:3.40.710.10 247 617 1.2E-98 T 13-10-2018 THITH_06305 2c48ad741f8c092481b1e87c4ea323b4 627 TIGRFAM TIGR03423 pbp2_mrdA: penicillin-binding protein 2 22 614 5.5E-227 T 13-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THITH_06305 2c48ad741f8c092481b1e87c4ea323b4 627 Gene3D G3DSA:3.30.1390.30 87 162 2.2E-49 T 13-10-2018 THITH_06305 2c48ad741f8c092481b1e87c4ea323b4 627 SUPERFAMILY SSF56519 58 251 4.97E-53 T 13-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 THITH_06305 2c48ad741f8c092481b1e87c4ea323b4 627 Gene3D G3DSA:3.90.1310.10 66 246 2.2E-49 T 13-10-2018 THITH_06305 2c48ad741f8c092481b1e87c4ea323b4 627 Hamap MF_02081 Peptidoglycan D,D-transpeptidase MrdA [mrdA]. 5 618 50.603 T 13-10-2018 IPR017790 Penicillin-binding protein 2 GO:0008658|GO:0009002|GO:0009252|GO:0016020 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THITH_06305 2c48ad741f8c092481b1e87c4ea323b4 627 Pfam PF03717 Penicillin-binding Protein dimerisation domain 66 237 9.6E-46 T 13-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 THITH_06305 2c48ad741f8c092481b1e87c4ea323b4 627 Pfam PF00905 Penicillin binding protein transpeptidase domain 269 611 7.6E-72 T 13-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 THITH_06305 2c48ad741f8c092481b1e87c4ea323b4 627 SUPERFAMILY SSF56601 252 615 3.11E-97 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like THITH_15615 392059dfaecd0387d6e5a2c224bf4f54 310 Pfam PF01218 Coproporphyrinogen III oxidase 13 304 3.5E-133 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THITH_15615 392059dfaecd0387d6e5a2c224bf4f54 310 SUPERFAMILY SSF102886 10 304 1.44E-138 T 13-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THITH_15615 392059dfaecd0387d6e5a2c224bf4f54 310 Gene3D G3DSA:3.40.1500.10 2 304 6.0E-138 T 13-10-2018 IPR036406 Oxygen-dependent coproporphyrinogen III oxidase superfamily GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THITH_15615 392059dfaecd0387d6e5a2c224bf4f54 310 Hamap MF_00333 Oxygen-dependent coproporphyrinogen-III oxidase [hemF]. 5 279 56.717 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THITH_15615 392059dfaecd0387d6e5a2c224bf4f54 310 PRINTS PR00073 Coprogen oxidase signature 164 193 4.6E-87 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THITH_15615 392059dfaecd0387d6e5a2c224bf4f54 310 PRINTS PR00073 Coprogen oxidase signature 50 71 4.6E-87 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THITH_15615 392059dfaecd0387d6e5a2c224bf4f54 310 PRINTS PR00073 Coprogen oxidase signature 33 49 4.6E-87 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THITH_15615 392059dfaecd0387d6e5a2c224bf4f54 310 PRINTS PR00073 Coprogen oxidase signature 92 116 4.6E-87 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THITH_15615 392059dfaecd0387d6e5a2c224bf4f54 310 PRINTS PR00073 Coprogen oxidase signature 236 263 4.6E-87 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THITH_15615 392059dfaecd0387d6e5a2c224bf4f54 310 PRINTS PR00073 Coprogen oxidase signature 127 149 4.6E-87 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THITH_15615 392059dfaecd0387d6e5a2c224bf4f54 310 PRINTS PR00073 Coprogen oxidase signature 264 290 4.6E-87 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THITH_15615 392059dfaecd0387d6e5a2c224bf4f54 310 PIRSF PIRSF000166 2 305 1.0E-128 T 13-10-2018 IPR001260 Coproporphyrinogen III oxidase, aerobic GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THITH_15615 392059dfaecd0387d6e5a2c224bf4f54 310 ProSitePatterns PS01021 Coproporphyrinogen III oxidase signature. 168 192 - T 13-10-2018 IPR018375 Coproporphyrinogen III oxidase, conserved site GO:0004109|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.3|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THITH_15920 ca436ec778d31e95ec575d933c451e31 242 PIRSF PIRSF006755 9 218 2.1E-42 T 13-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 THITH_15920 ca436ec778d31e95ec575d933c451e31 242 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 13 182 1.0E-35 T 13-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 THITH_15920 ca436ec778d31e95ec575d933c451e31 242 SUPERFAMILY SSF52540 11 208 8.3E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_15920 ca436ec778d31e95ec575d933c451e31 242 Pfam PF13500 AAA domain 12 205 4.1E-32 T 13-10-2018 THITH_15920 ca436ec778d31e95ec575d933c451e31 242 Gene3D G3DSA:3.40.50.300 11 219 2.9E-56 T 13-10-2018 THITH_15920 ca436ec778d31e95ec575d933c451e31 242 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 9 217 23.489 T 13-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 THITH_14980 76251e6f61d051e0e381e19fcb75b03f 336 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 196 209 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 THITH_14980 76251e6f61d051e0e381e19fcb75b03f 336 Gene3D G3DSA:3.90.1150.10 27 307 1.5E-51 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_14980 76251e6f61d051e0e381e19fcb75b03f 336 Gene3D G3DSA:3.40.640.10 39 244 1.5E-51 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_14980 76251e6f61d051e0e381e19fcb75b03f 336 SUPERFAMILY SSF53383 8 331 7.74E-58 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_14980 76251e6f61d051e0e381e19fcb75b03f 336 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 9 329 1.0E-109 T 13-10-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 THITH_14980 76251e6f61d051e0e381e19fcb75b03f 336 Pfam PF00155 Aminotransferase class I and II 72 318 4.2E-25 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THITH_12200 499e1e4e8f7d1a59422b5fe434f33501 111 SUPERFAMILY SSF55248 18 110 6.41E-28 T 13-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 THITH_12200 499e1e4e8f7d1a59422b5fe434f33501 111 Hamap MF_00434 Putative pterin-4-alpha-carbinolamine dehydratase. 16 110 20.943 T 13-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 THITH_12200 499e1e4e8f7d1a59422b5fe434f33501 111 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 18 108 3.5E-26 T 13-10-2018 IPR001533 Pterin 4 alpha carbinolamine dehydratase GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 THITH_12200 499e1e4e8f7d1a59422b5fe434f33501 111 Gene3D G3DSA:3.30.1360.20 19 111 7.8E-28 T 13-10-2018 IPR036428 Pterin 4 alpha carbinolamine dehydratase superfamily GO:0006729|GO:0008124 KEGG: 00790+4.2.1.96|MetaCyc: PWY-7158 THITH_12045 1df01000fa9da018b5e13d2f7d461743 112 Gene3D G3DSA:2.60.300.12 1 103 1.2E-41 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 THITH_12045 1df01000fa9da018b5e13d2f7d461743 112 SUPERFAMILY SSF89360 1 95 1.41E-19 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 THITH_12045 1df01000fa9da018b5e13d2f7d461743 112 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 2 96 6.8E-17 T 13-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 THITH_12045 1df01000fa9da018b5e13d2f7d461743 112 Pfam PF01521 Iron-sulphur cluster biosynthesis 2 81 5.0E-9 T 13-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THITH_13560 601c50f84be61f05bd7aaa7b80f10744 149 Gene3D G3DSA:3.10.450.30 69 149 5.2E-28 T 13-10-2018 THITH_13560 601c50f84be61f05bd7aaa7b80f10744 149 SUPERFAMILY SSF53933 75 149 6.24E-24 T 13-10-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 THITH_13560 601c50f84be61f05bd7aaa7b80f10744 149 Pfam PF00545 ribonuclease 75 146 1.5E-20 T 13-10-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 THITH_08930 988521ab8590861688111da8858c2c89 136 Pfam PF03713 Domain of unknown function (DUF305) 31 129 1.9E-20 T 13-10-2018 IPR005183 Domain of unknown function DUF305 THITH_08930 988521ab8590861688111da8858c2c89 136 Gene3D G3DSA:1.20.1260.10 75 136 9.5E-21 T 13-10-2018 IPR012347 Ferritin-like THITH_05300 dad60cddcca0fdb427cec5598f77502c 222 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 35 203 8.7E-12 T 13-10-2018 IPR010239 Conserved hypothetical protein CHP02001 THITH_05300 dad60cddcca0fdb427cec5598f77502c 222 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 13 209 4.4E-19 T 13-10-2018 IPR010239 Conserved hypothetical protein CHP02001 THITH_07845 525ee6ff5eefc087b5cc2fa42bb17ca5 1020 Hamap MF_00970 Ribonuclease E [rne]. 1 947 30.926 T 13-10-2018 IPR028878 Ribonuclease E GO:0006396|GO:0008995 THITH_07845 525ee6ff5eefc087b5cc2fa42bb17ca5 1020 Pfam PF00575 S1 RNA binding domain 37 116 5.3E-8 T 13-10-2018 IPR003029 S1 domain GO:0003676 THITH_07845 525ee6ff5eefc087b5cc2fa42bb17ca5 1020 SUPERFAMILY SSF50249 40 123 3.86E-15 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_07845 525ee6ff5eefc087b5cc2fa42bb17ca5 1020 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 13 422 4.1E-158 T 13-10-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 THITH_07845 525ee6ff5eefc087b5cc2fa42bb17ca5 1020 Gene3D G3DSA:3.40.1260.20 398 505 5.8E-36 T 13-10-2018 THITH_07845 525ee6ff5eefc087b5cc2fa42bb17ca5 1020 Gene3D G3DSA:2.40.50.140 32 123 1.8E-28 T 13-10-2018 THITH_07845 525ee6ff5eefc087b5cc2fa42bb17ca5 1020 SMART SM00316 37 117 4.0E-7 T 13-10-2018 IPR022967 RNA-binding domain, S1 THITH_07845 525ee6ff5eefc087b5cc2fa42bb17ca5 1020 Pfam PF10150 Ribonuclease E/G family 119 388 1.6E-93 T 13-10-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 THITH_08715 346aff87117ff7b363836bdcb7bff21f 213 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 6 199 4.4E-45 T 13-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 THITH_08715 346aff87117ff7b363836bdcb7bff21f 213 SUPERFAMILY SSF52540 5 211 4.5E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_08715 346aff87117ff7b363836bdcb7bff21f 213 Gene3D G3DSA:3.40.50.300 3 212 1.1E-64 T 13-10-2018 THITH_08715 346aff87117ff7b363836bdcb7bff21f 213 Pfam PF02223 Thymidylate kinase 11 199 4.3E-44 T 13-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 THITH_08715 346aff87117ff7b363836bdcb7bff21f 213 Hamap MF_00165 Thymidylate kinase [tmk]. 7 208 29.127 T 13-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 THITH_16985 cfcf4ad7d67a5d1286d3cb678b59dca5 289 Gene3D G3DSA:1.20.120.220 102 289 3.5E-50 T 13-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_16985 cfcf4ad7d67a5d1286d3cb678b59dca5 289 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 47 283 1.2E-40 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_16985 cfcf4ad7d67a5d1286d3cb678b59dca5 289 Pfam PF00119 ATP synthase A chain 53 281 2.9E-54 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_16985 cfcf4ad7d67a5d1286d3cb678b59dca5 289 ProSitePatterns PS00449 ATP synthase a subunit signature. 218 227 - T 13-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_16985 cfcf4ad7d67a5d1286d3cb678b59dca5 289 Hamap MF_01393 ATP synthase subunit a [atpB]. 10 288 15.033 T 13-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_16985 cfcf4ad7d67a5d1286d3cb678b59dca5 289 SUPERFAMILY SSF81336 103 282 4.45E-37 T 13-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_10005 deb2835af741e5a583f379266460dbca 165 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 1 82 4.1E-11 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THITH_10005 deb2835af741e5a583f379266460dbca 165 SUPERFAMILY SSF53254 1 127 2.65E-20 T 13-10-2018 IPR029033 Histidine phosphatase superfamily THITH_10005 deb2835af741e5a583f379266460dbca 165 Gene3D G3DSA:3.40.50.1240 1 163 7.6E-30 T 13-10-2018 IPR029033 Histidine phosphatase superfamily THITH_07330 7926a2c484602b9e281d1bbdff8f82c2 588 Pfam PF02080 TrkA-C domain 309 365 6.5E-9 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THITH_07330 7926a2c484602b9e281d1bbdff8f82c2 588 Pfam PF02080 TrkA-C domain 219 280 7.8E-7 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THITH_07330 7926a2c484602b9e281d1bbdff8f82c2 588 SUPERFAMILY SSF116726 296 383 5.49E-18 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_07330 7926a2c484602b9e281d1bbdff8f82c2 588 SUPERFAMILY SSF116726 212 291 3.4E-14 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_07330 7926a2c484602b9e281d1bbdff8f82c2 588 Pfam PF03600 Citrate transporter 416 585 3.7E-19 T 13-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 THITH_07330 7926a2c484602b9e281d1bbdff8f82c2 588 Pfam PF03600 Citrate transporter 31 193 1.1E-27 T 13-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 THITH_07330 7926a2c484602b9e281d1bbdff8f82c2 588 Gene3D G3DSA:3.30.70.1450 214 289 2.6E-10 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_07330 7926a2c484602b9e281d1bbdff8f82c2 588 Gene3D G3DSA:3.30.70.1450 304 377 2.8E-13 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_07215 de74dd50aa32aa8d62f2d39fca84f174 413 Gene3D G3DSA:3.30.565.60 254 407 6.9E-34 T 13-10-2018 IPR038475 RecG, C-terminal domain superfamily THITH_07215 de74dd50aa32aa8d62f2d39fca84f174 413 Gene3D G3DSA:3.30.950.30 2 136 2.8E-22 T 13-10-2018 IPR038461 Schlafen, AAA domain superfamily THITH_07215 de74dd50aa32aa8d62f2d39fca84f174 413 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 319 404 1.3E-18 T 13-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain THITH_07215 de74dd50aa32aa8d62f2d39fca84f174 413 Pfam PF04326 Putative DNA-binding domain 14 127 5.3E-18 T 13-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 THITH_06950 447940b5f785ed13cd44ba3605564a23 330 SUPERFAMILY SSF52518 23 303 2.95E-77 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold THITH_06950 447940b5f785ed13cd44ba3605564a23 330 Gene3D G3DSA:3.40.50.970 97 307 4.3E-63 T 13-10-2018 THITH_06950 447940b5f785ed13cd44ba3605564a23 330 Gene3D G3DSA:3.40.50.970 7 96 4.0E-17 T 13-10-2018 THITH_06950 447940b5f785ed13cd44ba3605564a23 330 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 55 216 6.1E-26 T 13-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 THITH_05250 055165ed584efd371aa2a1a864c52809 111 Gene3D G3DSA:3.30.70.120 4 111 2.4E-43 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THITH_05250 055165ed584efd371aa2a1a864c52809 111 SUPERFAMILY SSF54913 7 105 3.45E-35 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THITH_05250 055165ed584efd371aa2a1a864c52809 111 Pfam PF02641 Uncharacterized ACR, COG1993 11 104 4.4E-40 T 13-10-2018 IPR003793 Domain of unknown function DUF190 THITH_12815 830708133f3b28266be77c6e8a6665bc 306 Hamap MF_01428 Glutamyl-Q tRNA(Asp) synthetase [gluQ]. 4 299 38.376 T 13-10-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0004812|GO:0006400 THITH_12815 830708133f3b28266be77c6e8a6665bc 306 SUPERFAMILY SSF52374 4 246 2.65E-74 T 13-10-2018 THITH_12815 830708133f3b28266be77c6e8a6665bc 306 TIGRFAM TIGR03838 queuosine_YadB: glutamyl-queuosine tRNA(Asp) synthetase 4 263 4.7E-97 T 13-10-2018 IPR022380 Glutamyl-Q tRNA(Asp) synthetase GO:0000166|GO:0004812|GO:0006400 THITH_12815 830708133f3b28266be77c6e8a6665bc 306 PRINTS PR00987 Glutamyl-tRNA synthetase signature 36 49 2.5E-11 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THITH_12815 830708133f3b28266be77c6e8a6665bc 306 PRINTS PR00987 Glutamyl-tRNA synthetase signature 7 19 2.5E-11 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THITH_12815 830708133f3b28266be77c6e8a6665bc 306 PRINTS PR00987 Glutamyl-tRNA synthetase signature 21 32 2.5E-11 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THITH_12815 830708133f3b28266be77c6e8a6665bc 306 PRINTS PR00987 Glutamyl-tRNA synthetase signature 191 199 2.5E-11 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THITH_12815 830708133f3b28266be77c6e8a6665bc 306 PRINTS PR00987 Glutamyl-tRNA synthetase signature 175 185 2.5E-11 T 13-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 THITH_12815 830708133f3b28266be77c6e8a6665bc 306 Gene3D G3DSA:3.40.50.620 4 293 7.1E-88 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_12815 830708133f3b28266be77c6e8a6665bc 306 Gene3D G3DSA:3.40.50.620 79 223 7.1E-88 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_12815 830708133f3b28266be77c6e8a6665bc 306 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 7 241 5.8E-37 T 13-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 THITH_13985 9fb14afc809459523080c514539bc8fc 274 Hamap MF_00922 Outer membrane protein assembly factor BamD [bamD]. 1 240 36.142 T 13-10-2018 IPR017689 Outer membrane protein assembly factor BamD THITH_13985 9fb14afc809459523080c514539bc8fc 274 Pfam PF13525 Outer membrane lipoprotein 29 232 3.1E-67 T 13-10-2018 IPR039565 Outer membrane lipoprotein BamD-like THITH_13985 9fb14afc809459523080c514539bc8fc 274 Gene3D G3DSA:1.25.40.10 29 249 3.3E-57 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_13985 9fb14afc809459523080c514539bc8fc 274 TIGRFAM TIGR03302 OM_YfiO: outer membrane assembly lipoprotein YfiO 3 244 8.6E-81 T 13-10-2018 IPR017689 Outer membrane protein assembly factor BamD THITH_13985 9fb14afc809459523080c514539bc8fc 274 SUPERFAMILY SSF48452 30 158 1.64E-8 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_13550 e75fb5c3cd73fc49badabbcfd3a1fa33 248 ProSitePatterns PS00211 ABC transporters family signature. 154 168 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_13550 e75fb5c3cd73fc49badabbcfd3a1fa33 248 Pfam PF00005 ABC transporter 38 181 8.8E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_13550 e75fb5c3cd73fc49badabbcfd3a1fa33 248 Gene3D G3DSA:3.40.50.300 16 245 1.7E-62 T 13-10-2018 THITH_13550 e75fb5c3cd73fc49badabbcfd3a1fa33 248 SMART SM00382 47 232 4.4E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_13550 e75fb5c3cd73fc49badabbcfd3a1fa33 248 SUPERFAMILY SSF52540 19 237 2.03E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_03925 5b687b45037fced2c7e66c4e0566d9f1 172 SUPERFAMILY SSF50891 7 167 5.84E-58 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily THITH_03925 5b687b45037fced2c7e66c4e0566d9f1 172 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 47 59 7.6E-12 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 THITH_03925 5b687b45037fced2c7e66c4e0566d9f1 172 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 21 36 7.6E-12 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 THITH_03925 5b687b45037fced2c7e66c4e0566d9f1 172 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 124 139 7.6E-12 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 THITH_03925 5b687b45037fced2c7e66c4e0566d9f1 172 PIRSF PIRSF001467 1 170 1.5E-25 T 13-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 THITH_03925 5b687b45037fced2c7e66c4e0566d9f1 172 Gene3D G3DSA:2.40.100.10 4 169 8.1E-67 T 13-10-2018 IPR029000 Cyclophilin-like domain superfamily THITH_03925 5b687b45037fced2c7e66c4e0566d9f1 172 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 8 167 4.8E-47 T 13-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 THITH_03925 5b687b45037fced2c7e66c4e0566d9f1 172 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 42 59 - T 13-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 THITH_01545 51e00cdf7486df7a3467462ab8a1faee 531 Gene3D G3DSA:3.40.50.300 200 366 2.2E-6 T 13-10-2018 THITH_00125 41595e9eba1cba78d454af8591c21e14 153 TIGRFAM TIGR01710 typeII_sec_gspG: type II secretion system protein G 16 149 1.8E-57 T 13-10-2018 IPR010054 General secretion pathway protein G GO:0008565|GO:0015627|GO:0015628 THITH_00125 41595e9eba1cba78d454af8591c21e14 153 PRINTS PR00813 Bacterial general secretion pathway protein G signature 16 41 2.6E-19 T 13-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THITH_00125 41595e9eba1cba78d454af8591c21e14 153 PRINTS PR00813 Bacterial general secretion pathway protein G signature 52 70 2.6E-19 T 13-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 THITH_00125 41595e9eba1cba78d454af8591c21e14 153 Gene3D G3DSA:3.30.700.10 39 148 2.3E-38 T 13-10-2018 THITH_00125 41595e9eba1cba78d454af8591c21e14 153 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 15 35 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_00125 41595e9eba1cba78d454af8591c21e14 153 SUPERFAMILY SSF54523 43 149 2.46E-37 T 13-10-2018 THITH_00125 41595e9eba1cba78d454af8591c21e14 153 Pfam PF08334 Type II secretion system (T2SS), protein G 39 148 1.9E-40 T 13-10-2018 IPR013545 Type II secretion system protein G THITH_00125 41595e9eba1cba78d454af8591c21e14 153 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 16 37 1.4E-7 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_00125 41595e9eba1cba78d454af8591c21e14 153 Pfam PF07963 Prokaryotic N-terminal methylation motif 12 36 1.1E-8 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_13205 b7c0f6ee546a594aaa7b7b6738200b99 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.4E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_13205 b7c0f6ee546a594aaa7b7b6738200b99 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 3.4E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_13205 b7c0f6ee546a594aaa7b7b6738200b99 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 198 3.4E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_13205 b7c0f6ee546a594aaa7b7b6738200b99 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 3.4E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_13205 b7c0f6ee546a594aaa7b7b6738200b99 265 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 3.4E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_13205 b7c0f6ee546a594aaa7b7b6738200b99 265 PIRSF PIRSF000094 1 260 9.3E-115 T 13-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THITH_13205 b7c0f6ee546a594aaa7b7b6738200b99 265 SUPERFAMILY SSF51735 5 255 3.06E-63 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_13205 b7c0f6ee546a594aaa7b7b6738200b99 265 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 253 1.2E-83 T 13-10-2018 THITH_13205 b7c0f6ee546a594aaa7b7b6738200b99 265 Gene3D G3DSA:3.40.50.720 1 257 1.8E-55 T 13-10-2018 THITH_07320 070473f681e6f3611a20283926593c40 443 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 336 432 2.4E-17 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THITH_07320 070473f681e6f3611a20283926593c40 443 PIRSF PIRSF500136 1 442 6.2E-141 T 13-10-2018 IPR028359 UDP-N-acetyl-D-mannosamine/glucosamine dehydrogenase GO:0000271|GO:0016628|GO:0055114 THITH_07320 070473f681e6f3611a20283926593c40 443 Gene3D G3DSA:3.40.50.720 2 216 7.3E-53 T 13-10-2018 THITH_07320 070473f681e6f3611a20283926593c40 443 SUPERFAMILY SSF51735 7 210 9.99E-39 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_07320 070473f681e6f3611a20283926593c40 443 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 221 309 6.6E-25 T 13-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THITH_07320 070473f681e6f3611a20283926593c40 443 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 160 429 6.8E-73 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 THITH_07320 070473f681e6f3611a20283926593c40 443 SUPERFAMILY SSF48179 219 311 1.05E-25 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THITH_07320 070473f681e6f3611a20283926593c40 443 SUPERFAMILY SSF52413 319 435 1.31E-26 T 13-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 THITH_07320 070473f681e6f3611a20283926593c40 443 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 7 199 2.0E-27 T 13-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THITH_07320 070473f681e6f3611a20283926593c40 443 Gene3D G3DSA:3.40.50.720 219 441 4.0E-53 T 13-10-2018 THITH_07320 070473f681e6f3611a20283926593c40 443 PIRSF PIRSF000124 6 440 5.5E-47 T 13-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 THITH_07320 070473f681e6f3611a20283926593c40 443 SMART SM00984 336 436 9.2E-30 T 13-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 THITH_02395 cf8e5f9e82a7dad6062009f2846354eb 317 Pfam PF14397 Sugar-transfer associated ATP-grasp 20 293 5.7E-102 T 13-10-2018 IPR039523 Alpha-L-glutamate ligase-related protein, ATP-grasp domain KEGG: 00270+6.3.2.2+6.3.2.3|KEGG: 00480+6.3.2.2+6.3.2.3|MetaCyc: PWY-6840|MetaCyc: PWY-7255 THITH_02395 cf8e5f9e82a7dad6062009f2846354eb 317 SUPERFAMILY SSF56059 40 278 7.84E-18 T 13-10-2018 THITH_02395 cf8e5f9e82a7dad6062009f2846354eb 317 TIGRFAM TIGR02291 rimK_rel_E_lig: alpha-L-glutamate ligase homolog 4 313 1.8E-144 T 13-10-2018 IPR011758 Alpha-L-glutamate ligase-related protein THITH_16010 5ea4e992ff93e6acc93256be980d2624 130 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 1 123 3.8E-22 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 THITH_16010 5ea4e992ff93e6acc93256be980d2624 130 Gene3D G3DSA:3.30.420.140 1 130 3.6E-29 T 13-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 THITH_16010 5ea4e992ff93e6acc93256be980d2624 130 SUPERFAMILY SSF53098 1 125 7.44E-29 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_16010 5ea4e992ff93e6acc93256be980d2624 130 SMART SM00732 1 97 2.6E-15 T 13-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 THITH_16010 5ea4e992ff93e6acc93256be980d2624 130 Pfam PF03652 Holliday junction resolvase 1 124 8.3E-28 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 THITH_16010 5ea4e992ff93e6acc93256be980d2624 130 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 127 17.046 T 13-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 THITH_15200 926e5f1a18e7f91011c15c6ff15f7af7 587 Gene3D G3DSA:1.10.3720.10 301 562 1.7E-32 T 13-10-2018 IPR035906 MetI-like superfamily THITH_15200 926e5f1a18e7f91011c15c6ff15f7af7 587 SUPERFAMILY SSF161098 300 552 1.96E-37 T 13-10-2018 IPR035906 MetI-like superfamily THITH_15200 926e5f1a18e7f91011c15c6ff15f7af7 587 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 86 275 1.2E-8 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THITH_15200 926e5f1a18e7f91011c15c6ff15f7af7 587 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 360 551 7.4E-7 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THITH_15200 926e5f1a18e7f91011c15c6ff15f7af7 587 Gene3D G3DSA:1.10.3720.10 26 283 3.8E-46 T 13-10-2018 IPR035906 MetI-like superfamily THITH_15200 926e5f1a18e7f91011c15c6ff15f7af7 587 SUPERFAMILY SSF161098 21 276 2.22E-39 T 13-10-2018 IPR035906 MetI-like superfamily THITH_14485 e80af95390bc830b0b017f81c1ae31ec 462 Gene3D G3DSA:3.90.190.20 307 447 9.0E-38 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THITH_14485 e80af95390bc830b0b017f81c1ae31ec 462 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 445 33.161 T 13-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_14485 e80af95390bc830b0b017f81c1ae31ec 462 Gene3D G3DSA:3.40.1190.10 80 306 7.1E-71 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THITH_14485 e80af95390bc830b0b017f81c1ae31ec 462 Pfam PF01225 Mur ligase family, catalytic domain 26 62 1.1E-5 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 THITH_14485 e80af95390bc830b0b017f81c1ae31ec 462 SUPERFAMILY SSF53244 308 442 7.33E-31 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THITH_14485 e80af95390bc830b0b017f81c1ae31ec 462 Pfam PF02875 Mur ligase family, glutamate ligase domain 308 382 2.2E-12 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 THITH_14485 e80af95390bc830b0b017f81c1ae31ec 462 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 31 442 2.1E-123 T 13-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_14485 e80af95390bc830b0b017f81c1ae31ec 462 SUPERFAMILY SSF53623 99 306 4.06E-55 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THITH_14485 e80af95390bc830b0b017f81c1ae31ec 462 Pfam PF08245 Mur ligase middle domain 105 288 1.8E-44 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 THITH_14485 e80af95390bc830b0b017f81c1ae31ec 462 SUPERFAMILY SSF63418 1 95 4.84E-17 T 13-10-2018 IPR035911 MurE/MurF, N-terminal THITH_14485 e80af95390bc830b0b017f81c1ae31ec 462 Gene3D G3DSA:3.40.1390.10 1 79 4.7E-18 T 13-10-2018 THITH_16155 bbb31d1d6ab46eca854041ea3c9c40ac 297 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 3 123 2.9E-27 T 13-10-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI THITH_16155 bbb31d1d6ab46eca854041ea3c9c40ac 297 Gene3D G3DSA:1.25.40.10 149 288 4.4E-23 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_16155 bbb31d1d6ab46eca854041ea3c9c40ac 297 SUPERFAMILY SSF48452 146 263 2.01E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_07190 af66ba82b23d3c1b79347ecc904fd392 142 SUPERFAMILY SSF69819 7 142 2.22E-33 T 13-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 THITH_07190 af66ba82b23d3c1b79347ecc904fd392 142 Gene3D G3DSA:3.55.10.10 6 142 1.2E-33 T 13-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 THITH_07190 af66ba82b23d3c1b79347ecc904fd392 142 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 13 141 7.0E-29 T 13-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 THITH_07190 af66ba82b23d3c1b79347ecc904fd392 142 Pfam PF01951 Archease protein family (MTH1598/TM1083) 8 142 6.9E-33 T 13-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 THITH_11360 3167b76b362d06fe9e01e8b3b907772f 276 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 85 276 1.6E-81 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THITH_11360 3167b76b362d06fe9e01e8b3b907772f 276 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 3 86 2.9E-39 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THITH_11360 3167b76b362d06fe9e01e8b3b907772f 276 Hamap MF_00008 Thymidylate synthase [thyA]. 1 276 39.905 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THITH_11360 3167b76b362d06fe9e01e8b3b907772f 276 SUPERFAMILY SSF55831 1 276 4.45E-118 T 13-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THITH_11360 3167b76b362d06fe9e01e8b3b907772f 276 PRINTS PR00108 Thymidylate synthase family signature 42 63 5.6E-40 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THITH_11360 3167b76b362d06fe9e01e8b3b907772f 276 PRINTS PR00108 Thymidylate synthase family signature 153 168 5.6E-40 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THITH_11360 3167b76b362d06fe9e01e8b3b907772f 276 PRINTS PR00108 Thymidylate synthase family signature 209 226 5.6E-40 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THITH_11360 3167b76b362d06fe9e01e8b3b907772f 276 PRINTS PR00108 Thymidylate synthase family signature 171 197 5.6E-40 T 13-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THITH_11360 3167b76b362d06fe9e01e8b3b907772f 276 Pfam PF00303 Thymidylate synthase 3 276 1.1E-113 T 13-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THITH_11360 3167b76b362d06fe9e01e8b3b907772f 276 Gene3D G3DSA:3.30.572.10 1 276 7.6E-121 T 13-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 Gene3D G3DSA:3.30.565.10 856 1001 2.7E-39 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 SMART SM00065 619 767 0.13 T 13-10-2018 IPR003018 GAF domain GO:0005515 THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 SMART SM00065 445 598 0.0027 T 13-10-2018 IPR003018 GAF domain GO:0005515 THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 SMART SM00387 894 1000 5.5E-32 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 Gene3D G3DSA:3.30.450.40 603 771 8.9E-10 T 13-10-2018 IPR029016 GAF-like domain superfamily THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 Gene3D G3DSA:3.30.450.40 425 602 7.6E-19 T 13-10-2018 IPR029016 GAF-like domain superfamily THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 SUPERFAMILY SSF55781 605 779 5.89E-9 T 13-10-2018 THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 Gene3D G3DSA:1.10.287.130 772 852 1.4E-22 T 13-10-2018 THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 SUPERFAMILY SSF55874 855 999 2.23E-37 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 SUPERFAMILY SSF55781 426 600 3.93E-15 T 13-10-2018 THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 SUPERFAMILY SSF47384 783 852 8.04E-16 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 SMART SM00388 788 854 1.6E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 SUPERFAMILY SSF55781 300 439 2.68E-9 T 13-10-2018 THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 Gene3D G3DSA:3.30.450.40 298 424 6.2E-11 T 13-10-2018 IPR029016 GAF-like domain superfamily THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 Pfam PF13492 GAF domain 445 589 4.5E-10 T 13-10-2018 IPR003018 GAF domain GO:0005515 THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 897 999 2.1E-23 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 Pfam PF00512 His Kinase A (phospho-acceptor) domain 788 850 5.6E-15 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 PRINTS PR00344 Bacterial sensor protein C-terminal signature 949 959 1.3E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 PRINTS PR00344 Bacterial sensor protein C-terminal signature 984 997 1.3E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 PRINTS PR00344 Bacterial sensor protein C-terminal signature 931 945 1.3E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_13300 bd4ab43e0e280d20085029778992aa7a 1010 PRINTS PR00344 Bacterial sensor protein C-terminal signature 960 978 1.3E-16 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_05620 035abf0575968441ec367ca2a2874d9a 82 Gene3D G3DSA:1.10.1220.10 11 60 1.0E-15 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THITH_05620 035abf0575968441ec367ca2a2874d9a 82 SUPERFAMILY SSF47598 2 63 4.45E-17 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 THITH_13475 09eaee456295e284d879de439d5d1726 154 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 8 140 9.1E-37 T 13-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 THITH_13475 09eaee456295e284d879de439d5d1726 154 Gene3D G3DSA:3.40.50.300 3 150 1.9E-37 T 13-10-2018 THITH_13475 09eaee456295e284d879de439d5d1726 154 SUPERFAMILY SSF52540 33 127 1.33E-18 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13475 09eaee456295e284d879de439d5d1726 154 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 132 6.4E-34 T 13-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 THITH_09390 39fb87b3b8bf8ee08bfc5febd1245414 343 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 4 325 1.3E-172 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THITH_09390 39fb87b3b8bf8ee08bfc5febd1245414 343 PRINTS PR00142 RecA protein signature 94 123 1.2E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THITH_09390 39fb87b3b8bf8ee08bfc5febd1245414 343 PRINTS PR00142 RecA protein signature 211 239 1.2E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THITH_09390 39fb87b3b8bf8ee08bfc5febd1245414 343 PRINTS PR00142 RecA protein signature 128 157 1.2E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THITH_09390 39fb87b3b8bf8ee08bfc5febd1245414 343 PRINTS PR00142 RecA protein signature 166 195 1.2E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THITH_09390 39fb87b3b8bf8ee08bfc5febd1245414 343 PRINTS PR00142 RecA protein signature 298 315 1.2E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THITH_09390 39fb87b3b8bf8ee08bfc5febd1245414 343 PRINTS PR00142 RecA protein signature 244 273 1.2E-85 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THITH_09390 39fb87b3b8bf8ee08bfc5febd1245414 343 ProSitePatterns PS00321 recA signature. 214 222 - T 13-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 THITH_09390 39fb87b3b8bf8ee08bfc5febd1245414 343 Gene3D G3DSA:3.30.250.10 269 342 1.2E-27 T 13-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal THITH_09390 39fb87b3b8bf8ee08bfc5febd1245414 343 SUPERFAMILY SSF52540 4 268 1.02E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_09390 39fb87b3b8bf8ee08bfc5febd1245414 343 SUPERFAMILY SSF54752 269 326 4.58E-22 T 13-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal THITH_09390 39fb87b3b8bf8ee08bfc5febd1245414 343 Hamap MF_00268 Protein RecA [recA]. 5 330 52.374 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THITH_09390 39fb87b3b8bf8ee08bfc5febd1245414 343 Pfam PF00154 recA bacterial DNA recombination protein 7 269 1.4E-144 T 13-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 THITH_09390 39fb87b3b8bf8ee08bfc5febd1245414 343 SMART SM00382 58 229 5.2E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_09390 39fb87b3b8bf8ee08bfc5febd1245414 343 Gene3D G3DSA:3.40.50.300 30 268 9.2E-82 T 13-10-2018 THITH_09535 c21e63d0568221d73ed58f9b5d9b7e4d 137 Pfam PF06146 Phosphate-starvation-inducible E 51 117 8.6E-16 T 13-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like THITH_10755 3e7686dbb80b19f685965df4c79a5489 277 Gene3D G3DSA:3.20.20.70 1 271 1.5E-101 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_10755 3e7686dbb80b19f685965df4c79a5489 277 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 13-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THITH_10755 3e7686dbb80b19f685965df4c79a5489 277 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 264 34.824 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THITH_10755 3e7686dbb80b19f685965df4c79a5489 277 Pfam PF00290 Tryptophan synthase alpha chain 8 264 1.8E-88 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THITH_10755 3e7686dbb80b19f685965df4c79a5489 277 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 261 1.0E-74 T 13-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THITH_10755 3e7686dbb80b19f685965df4c79a5489 277 SUPERFAMILY SSF51366 2 264 1.32E-89 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 THITH_08215 a06d070bb504b0ae3b81b6fdf122d828 112 SUPERFAMILY SSF69721 2 107 6.93E-33 T 13-10-2018 IPR025526 DsrC-like domain superfamily THITH_08215 a06d070bb504b0ae3b81b6fdf122d828 112 PIRSF PIRSF006223 3 109 1.1E-33 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_08215 a06d070bb504b0ae3b81b6fdf122d828 112 Pfam PF04358 DsrC like protein 4 107 1.9E-35 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_08215 a06d070bb504b0ae3b81b6fdf122d828 112 Gene3D G3DSA:1.10.10.370 40 108 5.3E-25 T 13-10-2018 THITH_08215 a06d070bb504b0ae3b81b6fdf122d828 112 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 3 107 2.6E-31 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_08215 a06d070bb504b0ae3b81b6fdf122d828 112 Gene3D G3DSA:3.30.1420.10 1 39 1.6E-11 T 13-10-2018 THITH_08700 90c2a2baaf5c085d8d6251c3f8023ae9 370 Gene3D G3DSA:3.90.1150.10 10 360 6.2E-91 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_08700 90c2a2baaf5c085d8d6251c3f8023ae9 370 Pfam PF00266 Aminotransferase class-V 15 339 2.8E-44 T 13-10-2018 IPR000192 Aminotransferase class V domain THITH_08700 90c2a2baaf5c085d8d6251c3f8023ae9 370 Gene3D G3DSA:3.40.640.10 22 280 6.2E-91 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_08700 90c2a2baaf5c085d8d6251c3f8023ae9 370 SUPERFAMILY SSF53383 6 368 1.64E-75 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 Gene3D G3DSA:1.10.10.10 535 618 1.8E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 Pfam PF04545 Sigma-70, region 4 554 606 1.4E-19 T 13-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 Pfam PF04542 Sigma-70 region 2 385 454 1.7E-21 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 409 422 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 578 604 - T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 381 606 1.2E-38 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 SUPERFAMILY SSF88659 515 617 5.89E-27 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 Gene3D G3DSA:1.10.10.10 458 534 1.3E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 PRINTS PR00046 Major sigma-70 factor signature 409 422 3.2E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 PRINTS PR00046 Major sigma-70 factor signature 578 593 3.2E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 PRINTS PR00046 Major sigma-70 factor signature 433 441 3.2E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 PRINTS PR00046 Major sigma-70 factor signature 557 569 3.2E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 PRINTS PR00046 Major sigma-70 factor signature 593 604 3.2E-31 T 13-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 SUPERFAMILY SSF88659 458 532 5.67E-21 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 Gene3D G3DSA:1.10.220.120 2 65 1.7E-29 T 13-10-2018 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 SUPERFAMILY SSF88946 115 452 1.13E-97 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 381 617 2.2E-121 T 13-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 Pfam PF04546 Sigma-70, non-essential region 140 354 3.0E-56 T 13-10-2018 IPR007631 RNA polymerase sigma factor 70, non-essential domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 Pfam PF03979 Sigma-70 factor, region 1.1 4 81 3.9E-30 T 13-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 Pfam PF04539 Sigma-70 region 3 464 540 9.9E-31 T 13-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 Pfam PF00140 Sigma-70 factor, region 1.2 98 129 8.1E-13 T 13-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 5 618 44.427 T 13-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 THITH_15005 f0afb78964a6bc7222ab3a48a4ea7a83 620 Gene3D G3DSA:1.10.601.10 113 454 1.1E-124 T 13-10-2018 THITH_04215 33f4891c815ef4e5e1ab138d02a08c87 323 Gene3D G3DSA:3.90.550.10 2 242 2.3E-36 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_04215 33f4891c815ef4e5e1ab138d02a08c87 323 Pfam PF00535 Glycosyl transferase family 2 4 131 3.7E-27 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THITH_04215 33f4891c815ef4e5e1ab138d02a08c87 323 SUPERFAMILY SSF53448 3 233 1.67E-38 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_07305 5ddc5491f098d06a39ebb6140cf34828 181 Pfam PF01883 Iron-sulfur cluster assembly protein 84 158 1.6E-13 T 13-10-2018 IPR002744 MIP18 family-like THITH_07305 5ddc5491f098d06a39ebb6140cf34828 181 SUPERFAMILY SSF117916 80 179 4.25E-27 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily THITH_07305 5ddc5491f098d06a39ebb6140cf34828 181 TIGRFAM TIGR03406 FeS_long_SufT: probable FeS assembly SUF system protein SufT 8 180 2.3E-76 T 13-10-2018 IPR017776 FeS assembly SUF system protein SufT, putative THITH_07305 5ddc5491f098d06a39ebb6140cf34828 181 Gene3D G3DSA:3.30.300.130 73 180 1.4E-34 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily THITH_09045 586508431292e584da83751b59a2fc8a 614 SUPERFAMILY SSF51905 250 601 3.11E-20 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_09045 586508431292e584da83751b59a2fc8a 614 Pfam PF01266 FAD dependent oxidoreductase 250 580 1.9E-21 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THITH_09045 586508431292e584da83751b59a2fc8a 614 Pfam PF05430 S-adenosyl-L-methionine-dependent methyltransferase 121 235 2.7E-35 T 13-10-2018 IPR008471 MnmC-like methyltransferase GO:0016645|GO:0055114 MetaCyc: PWY-7892 THITH_09045 586508431292e584da83751b59a2fc8a 614 Hamap MF_01102 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC [mnmC]. 12 604 18.971 T 13-10-2018 IPR023032 tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC GO:0004808|GO:0008033|GO:0008168|GO:0016645|GO:0055114 MetaCyc: PWY-7892 THITH_09045 586508431292e584da83751b59a2fc8a 614 Gene3D G3DSA:3.50.50.60 251 602 1.4E-54 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_09045 586508431292e584da83751b59a2fc8a 614 Gene3D G3DSA:3.40.50.150 14 245 4.2E-75 T 13-10-2018 THITH_09045 586508431292e584da83751b59a2fc8a 614 Gene3D G3DSA:3.30.9.10 334 536 1.4E-54 T 13-10-2018 THITH_10675 281cfd8eff85a9ad57bb0f4425a6be65 481 Gene3D G3DSA:3.40.190.10 68 268 3.4E-13 T 13-10-2018 THITH_10675 281cfd8eff85a9ad57bb0f4425a6be65 481 SUPERFAMILY SSF53850 73 272 2.76E-14 T 13-10-2018 THITH_10675 281cfd8eff85a9ad57bb0f4425a6be65 481 Pfam PF01464 Transglycosylase SLT domain 298 404 7.0E-22 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 THITH_10675 281cfd8eff85a9ad57bb0f4425a6be65 481 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 316 344 - T 13-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 THITH_10675 281cfd8eff85a9ad57bb0f4425a6be65 481 SUPERFAMILY SSF53955 295 463 5.16E-38 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily THITH_10675 281cfd8eff85a9ad57bb0f4425a6be65 481 SMART SM00062 49 273 0.0053 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THITH_10675 281cfd8eff85a9ad57bb0f4425a6be65 481 Gene3D G3DSA:1.10.530.10 293 465 2.5E-35 T 13-10-2018 THITH_10675 281cfd8eff85a9ad57bb0f4425a6be65 481 Gene3D G3DSA:3.40.190.10 135 229 3.4E-13 T 13-10-2018 THITH_10675 281cfd8eff85a9ad57bb0f4425a6be65 481 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 77 272 1.3E-6 T 13-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF THITH_06845 ae7d129922686f4f60616378176ec167 338 PIRSF PIRSF005644 3 338 3.4E-131 T 13-10-2018 IPR011854 Carbamoyl dehydratase HypE THITH_06845 ae7d129922686f4f60616378176ec167 338 Gene3D G3DSA:3.30.1330.10 10 157 2.0E-52 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THITH_06845 ae7d129922686f4f60616378176ec167 338 SUPERFAMILY SSF55326 7 155 1.31E-34 T 13-10-2018 IPR036921 PurM-like, N-terminal domain superfamily THITH_06845 ae7d129922686f4f60616378176ec167 338 Gene3D G3DSA:3.90.650.10 158 338 1.6E-58 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THITH_06845 ae7d129922686f4f60616378176ec167 338 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 7 338 3.2E-146 T 13-10-2018 IPR011854 Carbamoyl dehydratase HypE THITH_06845 ae7d129922686f4f60616378176ec167 338 Pfam PF02769 AIR synthase related protein, C-terminal domain 164 315 1.7E-31 T 13-10-2018 IPR010918 PurM-like, C-terminal domain THITH_06845 ae7d129922686f4f60616378176ec167 338 SUPERFAMILY SSF56042 158 334 2.09E-49 T 13-10-2018 IPR036676 PurM-like, C-terminal domain superfamily THITH_06845 ae7d129922686f4f60616378176ec167 338 Pfam PF00586 AIR synthase related protein, N-terminal domain 52 152 1.3E-17 T 13-10-2018 IPR016188 PurM-like, N-terminal domain THITH_06075 324d08138d9e4ff83e204c311054976b 371 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 3 365 8.4E-165 T 13-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THITH_06075 324d08138d9e4ff83e204c311054976b 371 SUPERFAMILY SSF51713 1 361 1.96E-159 T 13-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THITH_06075 324d08138d9e4ff83e204c311054976b 371 Pfam PF01702 Queuine tRNA-ribosyltransferase 127 359 1.6E-88 T 13-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THITH_06075 324d08138d9e4ff83e204c311054976b 371 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 1 362 55.941 T 13-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THITH_06075 324d08138d9e4ff83e204c311054976b 371 Gene3D G3DSA:3.20.20.105 1 364 4.9E-165 T 13-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THITH_06075 324d08138d9e4ff83e204c311054976b 371 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 3 364 2.8E-158 T 13-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 THITH_04770 d57263d1f0d2d6908bfe53c16ec80717 444 Pfam PF00672 HAMP domain 182 227 5.9E-12 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_04770 d57263d1f0d2d6908bfe53c16ec80717 444 SMART SM00388 232 293 1.1E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_04770 d57263d1f0d2d6908bfe53c16ec80717 444 SMART SM00304 179 231 4.9E-11 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_04770 d57263d1f0d2d6908bfe53c16ec80717 444 SUPERFAMILY SSF158472 182 229 3.14E-6 T 13-10-2018 THITH_04770 d57263d1f0d2d6908bfe53c16ec80717 444 SUPERFAMILY SSF55874 288 440 5.11E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_04770 d57263d1f0d2d6908bfe53c16ec80717 444 Gene3D G3DSA:1.10.287.130 179 289 3.7E-23 T 13-10-2018 THITH_04770 d57263d1f0d2d6908bfe53c16ec80717 444 Gene3D G3DSA:3.30.565.10 295 442 2.5E-32 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_04770 d57263d1f0d2d6908bfe53c16ec80717 444 SUPERFAMILY SSF47384 215 289 1.1E-13 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_04770 d57263d1f0d2d6908bfe53c16ec80717 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 367 381 5.8E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_04770 d57263d1f0d2d6908bfe53c16ec80717 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 395 5.8E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_04770 d57263d1f0d2d6908bfe53c16ec80717 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 420 5.8E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_04770 d57263d1f0d2d6908bfe53c16ec80717 444 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 439 5.8E-12 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_04770 d57263d1f0d2d6908bfe53c16ec80717 444 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 335 440 8.0E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_04770 d57263d1f0d2d6908bfe53c16ec80717 444 Pfam PF00512 His Kinase A (phospho-acceptor) domain 233 290 4.9E-11 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_04770 d57263d1f0d2d6908bfe53c16ec80717 444 SMART SM00387 332 442 2.9E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_15555 23f8a47830c65299cd61ef8cc34bc7d0 459 SUPERFAMILY SSF51735 233 377 1.77E-28 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_15555 23f8a47830c65299cd61ef8cc34bc7d0 459 SUPERFAMILY SSF116726 137 219 1.57E-8 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_15555 23f8a47830c65299cd61ef8cc34bc7d0 459 Gene3D G3DSA:3.30.70.1450 369 459 1.6E-27 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_15555 23f8a47830c65299cd61ef8cc34bc7d0 459 Pfam PF02080 TrkA-C domain 392 451 8.1E-13 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THITH_15555 23f8a47830c65299cd61ef8cc34bc7d0 459 Pfam PF02080 TrkA-C domain 156 225 4.6E-10 T 13-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 THITH_15555 23f8a47830c65299cd61ef8cc34bc7d0 459 Gene3D G3DSA:3.40.50.720 3 139 5.5E-43 T 13-10-2018 THITH_15555 23f8a47830c65299cd61ef8cc34bc7d0 459 Pfam PF02254 TrkA-N domain 235 351 4.5E-23 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 THITH_15555 23f8a47830c65299cd61ef8cc34bc7d0 459 Pfam PF02254 TrkA-N domain 4 108 1.4E-24 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 THITH_15555 23f8a47830c65299cd61ef8cc34bc7d0 459 SUPERFAMILY SSF116726 392 449 8.63E-10 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_15555 23f8a47830c65299cd61ef8cc34bc7d0 459 Gene3D G3DSA:3.40.50.720 233 367 2.2E-30 T 13-10-2018 THITH_15555 23f8a47830c65299cd61ef8cc34bc7d0 459 PRINTS PR00335 TrkA potassium uptake protein signature 74 88 8.9E-21 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THITH_15555 23f8a47830c65299cd61ef8cc34bc7d0 459 PRINTS PR00335 TrkA potassium uptake protein signature 3 17 8.9E-21 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THITH_15555 23f8a47830c65299cd61ef8cc34bc7d0 459 PRINTS PR00335 TrkA potassium uptake protein signature 50 60 8.9E-21 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THITH_15555 23f8a47830c65299cd61ef8cc34bc7d0 459 PRINTS PR00335 TrkA potassium uptake protein signature 61 71 8.9E-21 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THITH_15555 23f8a47830c65299cd61ef8cc34bc7d0 459 PRINTS PR00335 TrkA potassium uptake protein signature 20 34 8.9E-21 T 13-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 THITH_15555 23f8a47830c65299cd61ef8cc34bc7d0 459 Gene3D G3DSA:3.30.70.1450 140 232 4.7E-18 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_15555 23f8a47830c65299cd61ef8cc34bc7d0 459 SUPERFAMILY SSF51735 2 152 4.38E-32 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_01285 2dfad5a49f1e3d2b7c3c7585a3ceae59 644 Gene3D G3DSA:1.10.287.380 563 644 6.2E-24 T 13-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 THITH_01285 2dfad5a49f1e3d2b7c3c7585a3ceae59 644 ProSitePatterns PS00211 ABC transporters family signature. 440 454 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_01285 2dfad5a49f1e3d2b7c3c7585a3ceae59 644 Gene3D G3DSA:3.40.50.300 10 278 5.9E-66 T 13-10-2018 THITH_01285 2dfad5a49f1e3d2b7c3c7585a3ceae59 644 SMART SM00382 343 514 1.8E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_01285 2dfad5a49f1e3d2b7c3c7585a3ceae59 644 SMART SM00382 28 229 4.8E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_01285 2dfad5a49f1e3d2b7c3c7585a3ceae59 644 Gene3D G3DSA:3.40.50.300 280 541 7.8E-64 T 13-10-2018 THITH_01285 2dfad5a49f1e3d2b7c3c7585a3ceae59 644 Pfam PF00005 ABC transporter 336 468 4.6E-23 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_01285 2dfad5a49f1e3d2b7c3c7585a3ceae59 644 Pfam PF00005 ABC transporter 19 184 7.8E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_01285 2dfad5a49f1e3d2b7c3c7585a3ceae59 644 SUPERFAMILY SSF52540 3 245 5.33E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01285 2dfad5a49f1e3d2b7c3c7585a3ceae59 644 Pfam PF16326 ABC transporter C-terminal domain 572 640 5.5E-21 T 13-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 THITH_01285 2dfad5a49f1e3d2b7c3c7585a3ceae59 644 Pfam PF12848 ABC transporter 223 299 1.8E-5 T 13-10-2018 IPR032781 ABC-transporter extension domain THITH_01285 2dfad5a49f1e3d2b7c3c7585a3ceae59 644 SUPERFAMILY SSF52540 304 513 1.85E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_11865 6f64a75ac7f97706f7e4e8400412d887 469 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 20 317 5.0E-117 T 13-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 THITH_11865 6f64a75ac7f97706f7e4e8400412d887 469 SUPERFAMILY SSF47323 321 460 1.26E-31 T 13-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_11865 6f64a75ac7f97706f7e4e8400412d887 469 SMART SM00840 344 403 6.9E-13 T 13-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 THITH_11865 6f64a75ac7f97706f7e4e8400412d887 469 Pfam PF09190 DALR domain 347 403 3.2E-10 T 13-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 THITH_11865 6f64a75ac7f97706f7e4e8400412d887 469 Gene3D G3DSA:3.40.50.620 1 309 9.2E-123 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_11865 6f64a75ac7f97706f7e4e8400412d887 469 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 5 461 37.273 T 13-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 THITH_11865 6f64a75ac7f97706f7e4e8400412d887 469 SUPERFAMILY SSF52374 6 317 1.13E-90 T 13-10-2018 THITH_11865 6f64a75ac7f97706f7e4e8400412d887 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 66 75 1.5E-28 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 THITH_11865 6f64a75ac7f97706f7e4e8400412d887 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 28 39 1.5E-28 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 THITH_11865 6f64a75ac7f97706f7e4e8400412d887 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 226 247 1.5E-28 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 THITH_11865 6f64a75ac7f97706f7e4e8400412d887 469 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 195 213 1.5E-28 T 13-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 THITH_11865 6f64a75ac7f97706f7e4e8400412d887 469 Gene3D G3DSA:1.20.120.640 310 461 8.2E-37 T 13-10-2018 THITH_11865 6f64a75ac7f97706f7e4e8400412d887 469 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 5 460 2.3E-146 T 13-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 THITH_07595 856e355db623141a7b0ad1953bcc3322 332 Pfam PF01032 FecCD transport family 25 329 3.3E-86 T 13-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 THITH_07595 856e355db623141a7b0ad1953bcc3322 332 Gene3D G3DSA:1.10.3470.10 11 332 8.8E-92 T 13-10-2018 IPR037294 ABC transporter, BtuC-like THITH_07595 856e355db623141a7b0ad1953bcc3322 332 SUPERFAMILY SSF81345 12 329 2.22E-73 T 13-10-2018 IPR037294 ABC transporter, BtuC-like THITH_00625 b13097a739f170f88072270f9d06aa63 78 Pfam PF00830 Ribosomal L28 family 3 61 4.6E-27 T 13-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_00625 b13097a739f170f88072270f9d06aa63 78 SUPERFAMILY SSF143800 2 77 5.1E-31 T 13-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_00625 b13097a739f170f88072270f9d06aa63 78 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 57 2.7E-28 T 13-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_00625 b13097a739f170f88072270f9d06aa63 78 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 67 22.028 T 13-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_00625 b13097a739f170f88072270f9d06aa63 78 Gene3D G3DSA:2.30.170.40 2 78 1.7E-33 T 13-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_09460 7c3e3b5be9912854ce608f5dd0d4e48a 682 SUPERFAMILY SSF54980 387 462 4.68E-17 T 13-10-2018 IPR035647 EF-G domain III/V-like THITH_09460 7c3e3b5be9912854ce608f5dd0d4e48a 682 Gene3D G3DSA:3.30.230.10 467 668 2.6E-71 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THITH_09460 7c3e3b5be9912854ce608f5dd0d4e48a 682 SMART SM00838 583 671 9.9E-14 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like THITH_09460 7c3e3b5be9912854ce608f5dd0d4e48a 682 SUPERFAMILY SSF50447 244 378 3.79E-23 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THITH_09460 7c3e3b5be9912854ce608f5dd0d4e48a 682 SUPERFAMILY SSF54980 586 674 6.23E-17 T 13-10-2018 IPR035647 EF-G domain III/V-like THITH_09460 7c3e3b5be9912854ce608f5dd0d4e48a 682 Pfam PF00679 Elongation factor G C-terminus 584 669 6.0E-19 T 13-10-2018 IPR000640 Elongation factor EFG, domain V-like THITH_09460 7c3e3b5be9912854ce608f5dd0d4e48a 682 Gene3D G3DSA:3.40.50.300 10 366 1.3E-71 T 13-10-2018 THITH_09460 7c3e3b5be9912854ce608f5dd0d4e48a 682 Pfam PF00009 Elongation factor Tu GTP binding domain 8 260 9.4E-29 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_09460 7c3e3b5be9912854ce608f5dd0d4e48a 682 SMART SM00889 463 581 2.0E-60 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THITH_09460 7c3e3b5be9912854ce608f5dd0d4e48a 682 Gene3D G3DSA:3.30.70.240 587 658 2.6E-71 T 13-10-2018 THITH_09460 7c3e3b5be9912854ce608f5dd0d4e48a 682 Gene3D G3DSA:3.30.70.870 388 466 1.7E-20 T 13-10-2018 THITH_09460 7c3e3b5be9912854ce608f5dd0d4e48a 682 Pfam PF03764 Elongation factor G, domain IV 462 580 3.8E-41 T 13-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 THITH_09460 7c3e3b5be9912854ce608f5dd0d4e48a 682 Pfam PF14492 Elongation Factor G, domain II 388 459 8.1E-21 T 13-10-2018 THITH_09460 7c3e3b5be9912854ce608f5dd0d4e48a 682 SUPERFAMILY SSF52540 6 260 4.83E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_09460 7c3e3b5be9912854ce608f5dd0d4e48a 682 SUPERFAMILY SSF54211 462 582 3.03E-40 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_09460 7c3e3b5be9912854ce608f5dd0d4e48a 682 Gene3D G3DSA:3.40.50.300 17 258 1.3E-71 T 13-10-2018 THITH_09040 b3551277e9f5ea5a122af2100e8edf86 509 Pfam PF01551 Peptidase family M23 366 459 1.8E-30 T 13-10-2018 IPR016047 Peptidase M23 THITH_09040 b3551277e9f5ea5a122af2100e8edf86 509 SUPERFAMILY SSF51261 267 459 1.41E-55 T 13-10-2018 IPR011055 Duplicated hybrid motif THITH_09040 b3551277e9f5ea5a122af2100e8edf86 509 Gene3D G3DSA:3.10.450.350 133 218 4.8E-6 T 13-10-2018 THITH_09040 b3551277e9f5ea5a122af2100e8edf86 509 Gene3D G3DSA:3.10.450.350 230 334 1.5E-15 T 13-10-2018 THITH_09040 b3551277e9f5ea5a122af2100e8edf86 509 Gene3D G3DSA:2.70.70.10 338 466 2.7E-46 T 13-10-2018 IPR011055 Duplicated hybrid motif THITH_09040 b3551277e9f5ea5a122af2100e8edf86 509 Pfam PF04225 Opacity-associated protein A LysM-like domain 140 223 3.9E-5 T 13-10-2018 IPR007340 Opacity-associated protein A THITH_15970 088878b16b49c4ba5fd0ba90c4f2d2ad 249 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 10 248 6.6E-42 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 THITH_15970 088878b16b49c4ba5fd0ba90c4f2d2ad 249 SUPERFAMILY SSF75217 76 248 5.67E-47 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases THITH_15970 088878b16b49c4ba5fd0ba90c4f2d2ad 249 Gene3D G3DSA:3.40.1280.10 76 249 9.2E-49 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THITH_15970 088878b16b49c4ba5fd0ba90c4f2d2ad 249 Gene3D G3DSA:2.40.240.20 1 70 4.5E-14 T 13-10-2018 THITH_15970 088878b16b49c4ba5fd0ba90c4f2d2ad 249 Pfam PF04452 RNA methyltransferase 21 242 1.7E-57 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 THITH_15970 088878b16b49c4ba5fd0ba90c4f2d2ad 249 PIRSF PIRSF015601 4 248 2.0E-50 T 13-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 THITH_15970 088878b16b49c4ba5fd0ba90c4f2d2ad 249 SUPERFAMILY SSF88697 7 67 1.64E-9 T 13-10-2018 IPR015947 PUA-like superfamily THITH_09770 0e6c8c27c05f4f586a86064640bf22fe 763 Pfam PF00082 Subtilase family 20 315 3.2E-35 T 13-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THITH_09770 0e6c8c27c05f4f586a86064640bf22fe 763 SUPERFAMILY SSF52743 5 330 4.58E-61 T 13-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 THITH_09770 0e6c8c27c05f4f586a86064640bf22fe 763 PRINTS PR00723 Subtilisin serine protease family (S8) signature 20 39 6.5E-14 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related THITH_09770 0e6c8c27c05f4f586a86064640bf22fe 763 PRINTS PR00723 Subtilisin serine protease family (S8) signature 84 97 6.5E-14 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related THITH_09770 0e6c8c27c05f4f586a86064640bf22fe 763 PRINTS PR00723 Subtilisin serine protease family (S8) signature 273 289 6.5E-14 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related THITH_09770 0e6c8c27c05f4f586a86064640bf22fe 763 Pfam PF07603 Protein of unknown function (DUF1566) 603 745 3.4E-17 T 13-10-2018 IPR011460 Protein of unknown function DUF1566 THITH_09770 0e6c8c27c05f4f586a86064640bf22fe 763 Gene3D G3DSA:3.40.50.200 2 337 1.3E-63 T 13-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 THITH_09770 0e6c8c27c05f4f586a86064640bf22fe 763 Gene3D G3DSA:2.60.40.10 491 585 1.3E-12 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_09770 0e6c8c27c05f4f586a86064640bf22fe 763 SUPERFAMILY SSF49265 493 581 4.53E-8 T 13-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 THITH_09770 0e6c8c27c05f4f586a86064640bf22fe 763 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 274 284 - T 13-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site THITH_05855 a378f17e8387b1ded18efcb689b38fb8 154 Gene3D G3DSA:3.10.420.10 33 147 1.2E-5 T 13-10-2018 IPR035958 SecB-like superfamily THITH_05855 a378f17e8387b1ded18efcb689b38fb8 154 SUPERFAMILY SSF54611 81 147 1.13E-10 T 13-10-2018 IPR035958 SecB-like superfamily THITH_05855 a378f17e8387b1ded18efcb689b38fb8 154 Pfam PF02556 Preprotein translocase subunit SecB 82 145 3.2E-5 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THITH_10700 1b0338c6ee56b72a4620b21f8ff0e5df 380 Pfam PF13466 STAS domain 26 96 3.8E-10 T 13-10-2018 IPR002645 STAS domain THITH_10700 1b0338c6ee56b72a4620b21f8ff0e5df 380 SUPERFAMILY SSF52091 23 100 1.2E-8 T 13-10-2018 IPR036513 STAS domain superfamily THITH_10700 1b0338c6ee56b72a4620b21f8ff0e5df 380 Pfam PF02405 Permease MlaE 167 374 2.6E-70 T 13-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 THITH_10700 1b0338c6ee56b72a4620b21f8ff0e5df 380 Gene3D G3DSA:3.30.750.24 20 109 3.7E-8 T 13-10-2018 IPR036513 STAS domain superfamily THITH_10700 1b0338c6ee56b72a4620b21f8ff0e5df 380 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 165 377 2.4E-65 T 13-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria THITH_12035 d5814fa97938c1b63a14ea592ca16ca3 418 Pfam PF03916 Polysulphide reductase, NrfD 49 337 4.9E-51 T 13-10-2018 IPR005614 NrfD family THITH_15675 2957cf508257d6dae44ddafce0137399 404 Gene3D G3DSA:3.40.50.1950 3 180 6.0E-56 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 THITH_15675 2957cf508257d6dae44ddafce0137399 404 Gene3D G3DSA:3.40.50.10300 183 399 4.5E-76 T 13-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 THITH_15675 2957cf508257d6dae44ddafce0137399 404 Pfam PF02441 Flavoprotein 8 179 1.2E-43 T 13-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 THITH_15675 2957cf508257d6dae44ddafce0137399 404 SUPERFAMILY SSF52507 5 178 2.22E-60 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 THITH_15675 2957cf508257d6dae44ddafce0137399 404 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 8 389 7.2E-133 T 13-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 THITH_15675 2957cf508257d6dae44ddafce0137399 404 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 185 365 4.2E-70 T 13-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 THITH_15675 2957cf508257d6dae44ddafce0137399 404 SUPERFAMILY SSF102645 183 394 1.44E-72 T 13-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 THITH_06205 315009fb6f2ba64019543266c8a29391 152 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 19 142 2.2E-25 T 13-10-2018 IPR005247 YbhB/YbcL THITH_06205 315009fb6f2ba64019543266c8a29391 152 Gene3D G3DSA:3.90.280.10 1 146 8.1E-42 T 13-10-2018 IPR036610 PEBP-like superfamily THITH_06205 315009fb6f2ba64019543266c8a29391 152 Pfam PF01161 Phosphatidylethanolamine-binding protein 23 141 2.3E-25 T 13-10-2018 IPR008914 Phosphatidylethanolamine-binding protein THITH_06205 315009fb6f2ba64019543266c8a29391 152 SUPERFAMILY SSF49777 1 142 1.31E-36 T 13-10-2018 IPR036610 PEBP-like superfamily THITH_17350 c382b310e21a469f4ff3ef3a8fe19e71 576 Pfam PF01019 Gamma-glutamyltranspeptidase 52 568 1.3E-156 T 13-10-2018 THITH_17350 c382b310e21a469f4ff3ef3a8fe19e71 576 Gene3D G3DSA:1.10.246.130 265 385 1.8E-29 T 13-10-2018 THITH_17350 c382b310e21a469f4ff3ef3a8fe19e71 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 384 402 1.7E-62 T 13-10-2018 THITH_17350 c382b310e21a469f4ff3ef3a8fe19e71 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 279 298 1.7E-62 T 13-10-2018 THITH_17350 c382b310e21a469f4ff3ef3a8fe19e71 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 151 170 1.7E-62 T 13-10-2018 THITH_17350 c382b310e21a469f4ff3ef3a8fe19e71 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 249 265 1.7E-62 T 13-10-2018 THITH_17350 c382b310e21a469f4ff3ef3a8fe19e71 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 133 151 1.7E-62 T 13-10-2018 THITH_17350 c382b310e21a469f4ff3ef3a8fe19e71 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 449 464 1.7E-62 T 13-10-2018 THITH_17350 c382b310e21a469f4ff3ef3a8fe19e71 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 59 84 1.7E-62 T 13-10-2018 THITH_17350 c382b310e21a469f4ff3ef3a8fe19e71 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 472 489 1.7E-62 T 13-10-2018 THITH_17350 c382b310e21a469f4ff3ef3a8fe19e71 576 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 408 426 1.7E-62 T 13-10-2018 THITH_17350 c382b310e21a469f4ff3ef3a8fe19e71 576 ProSitePatterns PS00462 Gamma-glutamyltranspeptidase signature. 384 408 - T 13-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 THITH_17350 c382b310e21a469f4ff3ef3a8fe19e71 576 Gene3D G3DSA:3.60.20.40 386 573 3.1E-56 T 13-10-2018 THITH_17350 c382b310e21a469f4ff3ef3a8fe19e71 576 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 39 565 1.1E-130 T 13-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 THITH_17350 c382b310e21a469f4ff3ef3a8fe19e71 576 SUPERFAMILY SSF56235 35 573 3.67E-160 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_10085 c3356ed520ad81c93b90575c9312a6c4 606 SMART SM00382 382 571 2.8E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_10085 c3356ed520ad81c93b90575c9312a6c4 606 SUPERFAMILY SSF52540 349 592 2.9E-76 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_10085 c3356ed520ad81c93b90575c9312a6c4 606 Pfam PF00664 ABC transporter transmembrane region 24 258 2.7E-14 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 THITH_10085 c3356ed520ad81c93b90575c9312a6c4 606 Gene3D G3DSA:1.20.1560.10 6 336 2.5E-24 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THITH_10085 c3356ed520ad81c93b90575c9312a6c4 606 Gene3D G3DSA:3.40.50.300 350 599 3.3E-80 T 13-10-2018 THITH_10085 c3356ed520ad81c93b90575c9312a6c4 606 ProSitePatterns PS00211 ABC transporters family signature. 497 511 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_10085 c3356ed520ad81c93b90575c9312a6c4 606 SUPERFAMILY SSF90123 8 334 5.1E-28 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THITH_10085 c3356ed520ad81c93b90575c9312a6c4 606 Pfam PF00005 ABC transporter 373 525 3.3E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_16450 d3d5e0eca241996a64ef6410ffd95020 325 SMART SM00963 25 104 7.2E-20 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THITH_16450 d3d5e0eca241996a64ef6410ffd95020 325 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 47 321 61.813 T 13-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 THITH_16450 d3d5e0eca241996a64ef6410ffd95020 325 SUPERFAMILY SSF47364 20 97 2.36E-18 T 13-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 THITH_16450 d3d5e0eca241996a64ef6410ffd95020 325 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 47 320 3.4E-105 T 13-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 THITH_16450 d3d5e0eca241996a64ef6410ffd95020 325 Pfam PF00448 SRP54-type protein, GTPase domain 121 320 2.8E-76 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THITH_16450 d3d5e0eca241996a64ef6410ffd95020 325 Pfam PF02881 SRP54-type protein, helical bundle domain 40 99 2.4E-11 T 13-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THITH_16450 d3d5e0eca241996a64ef6410ffd95020 325 SUPERFAMILY SSF52540 115 322 1.76E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16450 d3d5e0eca241996a64ef6410ffd95020 325 SMART SM00382 119 324 6.5E-9 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_16450 d3d5e0eca241996a64ef6410ffd95020 325 Gene3D G3DSA:1.20.120.140 22 319 4.4E-112 T 13-10-2018 THITH_16450 d3d5e0eca241996a64ef6410ffd95020 325 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 294 307 - T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THITH_16450 d3d5e0eca241996a64ef6410ffd95020 325 Gene3D G3DSA:3.40.50.300 108 309 4.4E-112 T 13-10-2018 THITH_16450 d3d5e0eca241996a64ef6410ffd95020 325 SMART SM00962 120 321 5.3E-116 T 13-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 THITH_01310 c01c26c66811bd66d258af00ee706bde 439 TIGRFAM TIGR01844 type_I_sec_TolC: type I secretion outer membrane protein, TolC family 22 437 9.6E-99 T 13-10-2018 IPR010130 Type I secretion outer membrane protein, TolC GO:0015562|GO:0019867|GO:0055085 THITH_01310 c01c26c66811bd66d258af00ee706bde 439 Pfam PF02321 Outer membrane efflux protein 27 211 2.5E-29 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 THITH_01310 c01c26c66811bd66d258af00ee706bde 439 Pfam PF02321 Outer membrane efflux protein 235 424 1.7E-35 T 13-10-2018 IPR003423 Outer membrane efflux protein GO:0015562|GO:0055085 THITH_01310 c01c26c66811bd66d258af00ee706bde 439 SUPERFAMILY SSF56954 1 426 1.11E-87 T 13-10-2018 THITH_01310 c01c26c66811bd66d258af00ee706bde 439 Gene3D G3DSA:1.20.1600.10 24 439 3.8E-112 T 13-10-2018 THITH_08360 8aef6e46009664d10e2cecb0a759d030 140 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 21 136 2.2E-35 T 13-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 THITH_08360 8aef6e46009664d10e2cecb0a759d030 140 Gene3D G3DSA:3.10.129.10 1 140 1.5E-53 T 13-10-2018 THITH_08360 8aef6e46009664d10e2cecb0a759d030 140 SUPERFAMILY SSF54637 5 137 5.45E-33 T 13-10-2018 IPR029069 HotDog domain superfamily THITH_08360 8aef6e46009664d10e2cecb0a759d030 140 Pfam PF03061 Thioesterase superfamily 51 128 1.2E-16 T 13-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 THITH_11995 1f102d21849287642c8c77a63a27dbd5 130 Pfam PF02635 DsrE/DsrF-like family 14 130 5.0E-29 T 13-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THITH_11995 1f102d21849287642c8c77a63a27dbd5 130 SUPERFAMILY SSF75169 13 130 1.44E-39 T 13-10-2018 IPR027396 DsrEFH-like THITH_11995 1f102d21849287642c8c77a63a27dbd5 130 TIGRFAM TIGR03010 sulf_tusC_dsrF: sulfur relay protein TusC/DsrF 15 130 3.4E-42 T 13-10-2018 IPR017462 Sulphur relay, TusC/DsrF THITH_11995 1f102d21849287642c8c77a63a27dbd5 130 Gene3D G3DSA:3.40.1260.10 11 130 7.9E-44 T 13-10-2018 IPR027396 DsrEFH-like THITH_01460 af2c1f4ff209a99702177895ddb8f676 201 Gene3D G3DSA:3.90.950.10 1 199 3.1E-77 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like THITH_01460 af2c1f4ff209a99702177895ddb8f676 201 Hamap MF_01405 dITP/XTP pyrophosphatase. 2 196 47.981 T 13-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 THITH_01460 af2c1f4ff209a99702177895ddb8f676 201 SUPERFAMILY SSF52972 1 195 2.22E-71 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like THITH_01460 af2c1f4ff209a99702177895ddb8f676 201 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 194 2.6E-55 T 13-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 THITH_01460 af2c1f4ff209a99702177895ddb8f676 201 Pfam PF01725 Ham1 family 4 192 5.3E-54 T 13-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 THITH_02315 df6019fe0594da5f81aa9155fb0c0a24 353 SUPERFAMILY SSF142754 31 341 9.68E-105 T 13-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 THITH_02315 df6019fe0594da5f81aa9155fb0c0a24 353 Pfam PF02445 Quinolinate synthetase A protein 34 340 1.0E-101 T 13-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 THITH_02315 df6019fe0594da5f81aa9155fb0c0a24 353 Gene3D G3DSA:3.40.50.10800 34 322 6.8E-92 T 13-10-2018 THITH_02315 df6019fe0594da5f81aa9155fb0c0a24 353 Gene3D G3DSA:3.40.50.10800 202 297 6.8E-92 T 13-10-2018 THITH_02315 df6019fe0594da5f81aa9155fb0c0a24 353 Gene3D G3DSA:3.40.50.10800 117 340 6.8E-92 T 13-10-2018 THITH_02315 df6019fe0594da5f81aa9155fb0c0a24 353 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 31 341 8.1E-105 T 13-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 THITH_06120 b6522d3274c1d7d63966f4264559f53a 193 Gene3D G3DSA:3.40.50.150 8 190 1.1E-31 T 13-10-2018 THITH_06120 b6522d3274c1d7d63966f4264559f53a 193 SUPERFAMILY SSF53335 7 177 7.0E-28 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_06120 b6522d3274c1d7d63966f4264559f53a 193 Pfam PF13649 Methyltransferase domain 41 127 9.6E-12 T 13-10-2018 THITH_17045 788b7009de5f76733f9a769a98d76c7f 420 Pfam PF13365 Trypsin-like peptidase domain 99 254 1.2E-33 T 13-10-2018 THITH_17045 788b7009de5f76733f9a769a98d76c7f 420 SMART SM00228 303 403 0.0069 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_17045 788b7009de5f76733f9a769a98d76c7f 420 Gene3D G3DSA:2.30.42.10 301 418 6.8E-19 T 13-10-2018 THITH_17045 788b7009de5f76733f9a769a98d76c7f 420 SUPERFAMILY SSF50494 63 288 8.36E-48 T 13-10-2018 IPR009003 Peptidase S1, PA clan THITH_17045 788b7009de5f76733f9a769a98d76c7f 420 Gene3D G3DSA:2.40.10.120 54 286 8.4E-57 T 13-10-2018 THITH_17045 788b7009de5f76733f9a769a98d76c7f 420 Pfam PF13180 PDZ domain 328 412 3.2E-9 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_17045 788b7009de5f76733f9a769a98d76c7f 420 PRINTS PR00834 HtrA/DegQ protease family signature 108 120 1.1E-30 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_17045 788b7009de5f76733f9a769a98d76c7f 420 PRINTS PR00834 HtrA/DegQ protease family signature 189 213 1.1E-30 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_17045 788b7009de5f76733f9a769a98d76c7f 420 PRINTS PR00834 HtrA/DegQ protease family signature 346 358 1.1E-30 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_17045 788b7009de5f76733f9a769a98d76c7f 420 PRINTS PR00834 HtrA/DegQ protease family signature 247 264 1.1E-30 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_17045 788b7009de5f76733f9a769a98d76c7f 420 PRINTS PR00834 HtrA/DegQ protease family signature 225 242 1.1E-30 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_17045 788b7009de5f76733f9a769a98d76c7f 420 SUPERFAMILY SSF50156 303 414 7.69E-12 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 THITH_06730 5ce4b04259df173dc4419316667c9260 161 Gene3D G3DSA:2.60.120.10 6 151 3.4E-29 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_06730 5ce4b04259df173dc4419316667c9260 161 SUPERFAMILY SSF51206 9 142 8.64E-27 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like THITH_06730 5ce4b04259df173dc4419316667c9260 161 Pfam PF00027 Cyclic nucleotide-binding domain 34 121 7.2E-19 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain THITH_06730 5ce4b04259df173dc4419316667c9260 161 SMART SM00100 15 133 2.5E-16 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain THITH_14345 3499af0fb0e064a9f41f70ff1e2b5105 143 SMART SM00649 9 141 2.9E-87 T 13-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 THITH_14345 3499af0fb0e064a9f41f70ff1e2b5105 143 SUPERFAMILY SSF54747 3 73 2.62E-30 T 13-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily THITH_14345 3499af0fb0e064a9f41f70ff1e2b5105 143 Gene3D G3DSA:1.10.10.250 73 141 6.0E-28 T 13-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily THITH_14345 3499af0fb0e064a9f41f70ff1e2b5105 143 Gene3D G3DSA:3.30.1550.10 2 72 1.5E-35 T 13-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily THITH_14345 3499af0fb0e064a9f41f70ff1e2b5105 143 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 67 4.1E-31 T 13-10-2018 IPR020784 Ribosomal protein L11, N-terminal THITH_14345 3499af0fb0e064a9f41f70ff1e2b5105 143 SUPERFAMILY SSF46906 68 141 3.79E-26 T 13-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily THITH_14345 3499af0fb0e064a9f41f70ff1e2b5105 143 Pfam PF00298 Ribosomal protein L11, RNA binding domain 72 140 3.3E-25 T 13-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 THITH_14345 3499af0fb0e064a9f41f70ff1e2b5105 143 ProSitePatterns PS00359 Ribosomal protein L11 signature. 127 142 - T 13-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14345 3499af0fb0e064a9f41f70ff1e2b5105 143 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 74 1.0E-14 T 13-10-2018 THITH_14345 3499af0fb0e064a9f41f70ff1e2b5105 143 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 142 32.01 T 13-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 THITH_14345 3499af0fb0e064a9f41f70ff1e2b5105 143 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 1.6E-65 T 13-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_07665 05d546a29d3d4dd69b96d2dcdba070a3 471 SUPERFAMILY SSF52440 1 111 6.47E-46 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily THITH_07665 05d546a29d3d4dd69b96d2dcdba070a3 471 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 284 291 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THITH_07665 05d546a29d3d4dd69b96d2dcdba070a3 471 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 113 320 8.0E-76 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THITH_07665 05d546a29d3d4dd69b96d2dcdba070a3 471 SMART SM00878 334 440 7.4E-58 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THITH_07665 05d546a29d3d4dd69b96d2dcdba070a3 471 SUPERFAMILY SSF51246 329 445 1.52E-41 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 THITH_07665 05d546a29d3d4dd69b96d2dcdba070a3 471 Gene3D G3DSA:3.30.470.130 1 448 1.6E-192 T 13-10-2018 THITH_07665 05d546a29d3d4dd69b96d2dcdba070a3 471 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 2 442 1.2E-190 T 13-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 THITH_07665 05d546a29d3d4dd69b96d2dcdba070a3 471 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 108 1.4E-43 T 13-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THITH_07665 05d546a29d3d4dd69b96d2dcdba070a3 471 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 151 165 - T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THITH_07665 05d546a29d3d4dd69b96d2dcdba070a3 471 Pfam PF02785 Biotin carboxylase C-terminal domain 334 440 1.9E-37 T 13-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THITH_07665 05d546a29d3d4dd69b96d2dcdba070a3 471 SUPERFAMILY SSF56059 81 346 1.01E-67 T 13-10-2018 THITH_11545 08f31222a816a49673e13ecfc952b3ad 252 Gene3D G3DSA:1.10.150.690 26 115 6.2E-26 T 13-10-2018 THITH_11545 08f31222a816a49673e13ecfc952b3ad 252 Pfam PF09836 Putative DNA-binding domain 1 86 7.9E-26 T 13-10-2018 IPR018640 Putative DNA-binding domain, bacteria THITH_12365 8ee58c442b04874a27311f17a299d94f 114 Pfam PF00101 Ribulose bisphosphate carboxylase, small chain 17 110 1.5E-38 T 13-10-2018 IPR000894 Ribulose bisphosphate carboxylase small chain, domain KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THITH_12365 8ee58c442b04874a27311f17a299d94f 114 SMART SM00961 15 112 1.4E-46 T 13-10-2018 IPR000894 Ribulose bisphosphate carboxylase small chain, domain KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THITH_12365 8ee58c442b04874a27311f17a299d94f 114 Gene3D G3DSA:3.30.190.10 4 113 4.7E-41 T 13-10-2018 IPR036385 Ribulose bisphosphate carboxylase, small subunit superfamily KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THITH_12365 8ee58c442b04874a27311f17a299d94f 114 SUPERFAMILY SSF55239 7 111 2.22E-39 T 13-10-2018 IPR036385 Ribulose bisphosphate carboxylase, small subunit superfamily KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THITH_03560 d5fdebbb6d7f8f546e42bb509170d673 453 SMART SM00382 203 401 0.0037 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_03560 d5fdebbb6d7f8f546e42bb509170d673 453 Pfam PF00772 DnaB-like helicase N terminal domain 8 109 1.9E-36 T 13-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 THITH_03560 d5fdebbb6d7f8f546e42bb509170d673 453 Gene3D G3DSA:3.40.50.300 169 447 1.8E-107 T 13-10-2018 THITH_03560 d5fdebbb6d7f8f546e42bb509170d673 453 Pfam PF03796 DnaB-like helicase C terminal domain 186 441 7.9E-118 T 13-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 THITH_03560 d5fdebbb6d7f8f546e42bb509170d673 453 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 8 442 3.5E-179 T 13-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 THITH_03560 d5fdebbb6d7f8f546e42bb509170d673 453 TIGRFAM TIGR03600 phage_DnaB: phage replicative helicase, DnaB family 11 432 2.1E-150 T 13-10-2018 IPR019889 DNA helicase, DnaB-like, phage THITH_03560 d5fdebbb6d7f8f546e42bb509170d673 453 Gene3D G3DSA:1.10.860.10 2 167 1.1E-55 T 13-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal THITH_03560 d5fdebbb6d7f8f546e42bb509170d673 453 SUPERFAMILY SSF52540 184 435 3.75E-55 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_03560 d5fdebbb6d7f8f546e42bb509170d673 453 SUPERFAMILY SSF48024 6 117 1.05E-39 T 13-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 THITH_11635 65b6e496e85e15789df5eb986140f191 400 Gene3D G3DSA:3.40.50.2000 27 200 4.9E-67 T 13-10-2018 THITH_11635 65b6e496e85e15789df5eb986140f191 400 SUPERFAMILY SSF53756 24 393 9.77E-79 T 13-10-2018 THITH_11635 65b6e496e85e15789df5eb986140f191 400 Gene3D G3DSA:3.40.50.2000 201 380 4.9E-67 T 13-10-2018 THITH_11635 65b6e496e85e15789df5eb986140f191 400 Pfam PF13439 Glycosyltransferase Family 4 36 204 2.4E-24 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 THITH_11635 65b6e496e85e15789df5eb986140f191 400 Pfam PF00534 Glycosyl transferases group 1 211 372 2.7E-28 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 THITH_04385 caf83c216bc9f2fb98e5ba7e6ae70d06 192 Pfam PF02508 Rnf-Nqr subunit, membrane protein 4 189 4.9E-61 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 THITH_04385 caf83c216bc9f2fb98e5ba7e6ae70d06 192 TIGRFAM TIGR01943 rnfA: electron transport complex, RnfABCDGE type, A subunit 2 190 3.9E-87 T 13-10-2018 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA GO:0022900 THITH_04385 caf83c216bc9f2fb98e5ba7e6ae70d06 192 Hamap MF_00459 Ion-translocating oxidoreductase complex subunit A [rsxA]. 1 190 25.817 T 13-10-2018 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA GO:0022900 THITH_04385 caf83c216bc9f2fb98e5ba7e6ae70d06 192 PIRSF PIRSF006102 1 192 3.5E-61 T 13-10-2018 IPR003667 NqrDE/RnfAE GO:0016020 THITH_17335 179c34a6376331c9bdeba8de031de791 332 Gene3D G3DSA:1.25.40.10 188 308 2.3E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_17335 179c34a6376331c9bdeba8de031de791 332 Pfam PF13529 Peptidase_C39 like family 42 146 1.0E-9 T 13-10-2018 IPR039564 Peptidase C39-like THITH_17335 179c34a6376331c9bdeba8de031de791 332 Gene3D G3DSA:3.90.70.10 46 187 1.0E-12 T 13-10-2018 THITH_17335 179c34a6376331c9bdeba8de031de791 332 SUPERFAMILY SSF48452 193 292 4.43E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_07380 d4d6ec51be2d28cd9ada569beffa9fb4 558 SUPERFAMILY SSF48452 263 448 3.32E-24 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_07380 d4d6ec51be2d28cd9ada569beffa9fb4 558 SUPERFAMILY SSF48452 78 239 1.75E-22 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_07380 d4d6ec51be2d28cd9ada569beffa9fb4 558 Gene3D G3DSA:1.25.40.10 245 521 2.8E-25 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_07380 d4d6ec51be2d28cd9ada569beffa9fb4 558 SMART SM00028 181 214 12.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_07380 d4d6ec51be2d28cd9ada569beffa9fb4 558 SMART SM00028 113 146 21.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_07380 d4d6ec51be2d28cd9ada569beffa9fb4 558 SMART SM00028 79 112 0.15 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_07380 d4d6ec51be2d28cd9ada569beffa9fb4 558 SMART SM00028 147 180 150.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_07380 d4d6ec51be2d28cd9ada569beffa9fb4 558 SMART SM00028 365 398 110.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_07380 d4d6ec51be2d28cd9ada569beffa9fb4 558 SMART SM00028 263 296 0.8 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_07380 d4d6ec51be2d28cd9ada569beffa9fb4 558 SMART SM00028 331 364 0.0061 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_07380 d4d6ec51be2d28cd9ada569beffa9fb4 558 Gene3D G3DSA:1.25.40.10 186 244 4.7E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_07380 d4d6ec51be2d28cd9ada569beffa9fb4 558 Gene3D G3DSA:1.25.40.10 50 177 7.0E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_07380 d4d6ec51be2d28cd9ada569beffa9fb4 558 Pfam PF14559 Tetratricopeptide repeat 126 179 4.7E-9 T 13-10-2018 THITH_07380 d4d6ec51be2d28cd9ada569beffa9fb4 558 Pfam PF14559 Tetratricopeptide repeat 277 333 2.4E-7 T 13-10-2018 THITH_07380 d4d6ec51be2d28cd9ada569beffa9fb4 558 Pfam PF14559 Tetratricopeptide repeat 343 406 1.0E-5 T 13-10-2018 THITH_07380 d4d6ec51be2d28cd9ada569beffa9fb4 558 Pfam PF14559 Tetratricopeptide repeat 191 246 8.0E-6 T 13-10-2018 THITH_11125 41e4adfbc1bd5bcfcf6ba986669cb7ad 248 Pfam PF08808 RES domain 62 208 1.2E-25 T 13-10-2018 IPR014914 RES domain THITH_11125 41e4adfbc1bd5bcfcf6ba986669cb7ad 248 SMART SM00953 70 206 2.3E-25 T 13-10-2018 IPR014914 RES domain THITH_03905 f2eabfdcfa0c545fab16018e2dfba7e7 428 Gene3D G3DSA:1.20.1250.20 3 188 6.2E-12 T 13-10-2018 THITH_03905 f2eabfdcfa0c545fab16018e2dfba7e7 428 SUPERFAMILY SSF103473 6 384 3.14E-35 T 13-10-2018 IPR036259 MFS transporter superfamily THITH_03905 f2eabfdcfa0c545fab16018e2dfba7e7 428 Gene3D G3DSA:1.20.1250.20 201 380 3.0E-14 T 13-10-2018 THITH_03905 f2eabfdcfa0c545fab16018e2dfba7e7 428 Pfam PF07690 Major Facilitator Superfamily 205 383 1.4E-11 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THITH_07660 31d92af6fd56feff3084b39a4bd2ff9d 610 Pfam PF00682 HMGL-like 4 268 3.8E-49 T 13-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 THITH_07660 31d92af6fd56feff3084b39a4bd2ff9d 610 SUPERFAMILY SSF51569 1 299 2.38E-89 T 13-10-2018 THITH_07660 31d92af6fd56feff3084b39a4bd2ff9d 610 Pfam PF02436 Conserved carboxylase domain 291 479 5.9E-55 T 13-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 THITH_07660 31d92af6fd56feff3084b39a4bd2ff9d 610 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 6 605 4.1E-249 T 13-10-2018 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 THITH_07660 31d92af6fd56feff3084b39a4bd2ff9d 610 SUPERFAMILY SSF51230 537 609 2.49E-20 T 13-10-2018 IPR011053 Single hybrid motif THITH_07660 31d92af6fd56feff3084b39a4bd2ff9d 610 Gene3D G3DSA:2.40.50.100 535 610 1.9E-23 T 13-10-2018 THITH_07660 31d92af6fd56feff3084b39a4bd2ff9d 610 Pfam PF00364 Biotin-requiring enzyme 542 608 6.0E-17 T 13-10-2018 IPR000089 Biotin/lipoyl attachment THITH_07660 31d92af6fd56feff3084b39a4bd2ff9d 610 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 565 582 - T 13-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THITH_07660 31d92af6fd56feff3084b39a4bd2ff9d 610 SUPERFAMILY SSF89000 296 449 1.45E-49 T 13-10-2018 THITH_07660 31d92af6fd56feff3084b39a4bd2ff9d 610 Gene3D G3DSA:3.20.20.70 1 453 2.2E-168 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_16095 02cd35264897cca2d9e044c686b89505 347 Gene3D G3DSA:3.60.60.10 22 341 8.9E-122 T 13-10-2018 THITH_16095 02cd35264897cca2d9e044c686b89505 347 SUPERFAMILY SSF56235 25 318 4.86E-96 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_16095 02cd35264897cca2d9e044c686b89505 347 Pfam PF02275 Linear amide C-N hydrolases, choloylglycine hydrolase family 25 311 3.3E-48 T 13-10-2018 IPR029132 Choloylglycine hydrolase/NAAA C-terminal THITH_11985 62eea022fed9517a8d835065688cba4d 358 Gene3D G3DSA:3.30.70.3340 2 124 1.9E-43 T 13-10-2018 THITH_11985 62eea022fed9517a8d835065688cba4d 358 Gene3D G3DSA:3.30.70.20 191 251 1.2E-88 T 13-10-2018 THITH_11985 62eea022fed9517a8d835065688cba4d 358 TIGRFAM TIGR02066 dsrB: sulfite reductase, dissimilatory-type beta subunit 25 358 1.1E-165 T 13-10-2018 IPR011808 Sulphite reductase, dissimilatory-type beta subunit GO:0006790|GO:0009055|GO:0018551|GO:0051539 KEGG: 00633+1.8.99.5|KEGG: 00920+1.8.99.5|MetaCyc: PWY-5306|MetaCyc: PWY-5360 THITH_11985 62eea022fed9517a8d835065688cba4d 358 SUPERFAMILY SSF54862 167 249 4.95E-8 T 13-10-2018 THITH_11985 62eea022fed9517a8d835065688cba4d 358 Gene3D G3DSA:3.30.413.10 125 344 1.2E-88 T 13-10-2018 THITH_11985 62eea022fed9517a8d835065688cba4d 358 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 236 247 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_11985 62eea022fed9517a8d835065688cba4d 358 SUPERFAMILY SSF55124 7 126 1.08E-41 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THITH_11985 62eea022fed9517a8d835065688cba4d 358 SUPERFAMILY SSF56014 121 344 1.07E-32 T 13-10-2018 THITH_11985 62eea022fed9517a8d835065688cba4d 358 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 122 336 5.3E-24 T 13-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THITH_11985 62eea022fed9517a8d835065688cba4d 358 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 51 111 5.0E-7 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THITH_03655 571bf4c2bcdc025906189646113140e5 270 SMART SM00986 114 261 2.7E-45 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THITH_03655 571bf4c2bcdc025906189646113140e5 270 SMART SM00987 114 261 2.7E-45 T 13-10-2018 THITH_03655 571bf4c2bcdc025906189646113140e5 270 Pfam PF03167 Uracil DNA glycosylase superfamily 114 260 4.9E-46 T 13-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THITH_03655 571bf4c2bcdc025906189646113140e5 270 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 99 264 2.2E-61 T 13-10-2018 IPR005273 Uracil-DNA glycosylase family 4 THITH_03655 571bf4c2bcdc025906189646113140e5 270 SUPERFAMILY SSF52141 89 267 5.23E-61 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THITH_03655 571bf4c2bcdc025906189646113140e5 270 Gene3D G3DSA:3.40.470.10 87 269 1.9E-71 T 13-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 THITH_03305 a061f764247cd7af483ab78bff7b558f 305 Gene3D G3DSA:3.20.20.150 5 302 6.2E-75 T 13-10-2018 THITH_03305 a061f764247cd7af483ab78bff7b558f 305 TIGRFAM TIGR04379 myo_inos_iolE: myo-inosose-2 dehydratase 11 302 1.2E-104 T 13-10-2018 IPR030823 IolE/MocC family KEGG: 00562+4.2.1.44 THITH_03305 a061f764247cd7af483ab78bff7b558f 305 SUPERFAMILY SSF51658 15 303 1.66E-51 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily THITH_03305 a061f764247cd7af483ab78bff7b558f 305 Pfam PF01261 Xylose isomerase-like TIM barrel 52 227 1.3E-24 T 13-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain THITH_05295 e5c9f5fe1642ad2eb8ec2f7396252699 461 SUPERFAMILY SSF161093 284 455 3.53E-42 T 13-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 THITH_05295 e5c9f5fe1642ad2eb8ec2f7396252699 461 Gene3D G3DSA:1.25.60.10 1 122 2.0E-10 T 13-10-2018 IPR038076 MgtE, N-terminal domain superfamily THITH_05295 e5c9f5fe1642ad2eb8ec2f7396252699 461 SMART SM00924 24 127 3.2E-12 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain THITH_05295 e5c9f5fe1642ad2eb8ec2f7396252699 461 Pfam PF01769 Divalent cation transporter 322 448 6.3E-25 T 13-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 THITH_05295 e5c9f5fe1642ad2eb8ec2f7396252699 461 Gene3D G3DSA:1.10.357.20 278 456 1.5E-48 T 13-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain THITH_05295 e5c9f5fe1642ad2eb8ec2f7396252699 461 SUPERFAMILY SSF54631 127 260 1.09E-23 T 13-10-2018 THITH_05295 e5c9f5fe1642ad2eb8ec2f7396252699 461 Pfam PF03448 MgtE intracellular N domain 26 123 4.8E-14 T 13-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain THITH_05295 e5c9f5fe1642ad2eb8ec2f7396252699 461 Pfam PF00571 CBS domain 203 246 0.0013 T 13-10-2018 IPR000644 CBS domain THITH_05295 e5c9f5fe1642ad2eb8ec2f7396252699 461 Pfam PF00571 CBS domain 127 186 6.0E-6 T 13-10-2018 IPR000644 CBS domain THITH_05295 e5c9f5fe1642ad2eb8ec2f7396252699 461 SUPERFAMILY SSF158791 6 123 1.07E-15 T 13-10-2018 THITH_05295 e5c9f5fe1642ad2eb8ec2f7396252699 461 Gene3D G3DSA:3.10.580.10 124 251 1.9E-27 T 13-10-2018 THITH_05295 e5c9f5fe1642ad2eb8ec2f7396252699 461 TIGRFAM TIGR00400 mgtE: magnesium transporter 9 456 2.9E-78 T 13-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 THITH_05035 ebad4edd083ac87f9fcd0942c38e1542 201 Gene3D G3DSA:3.40.50.150 12 185 8.8E-27 T 13-10-2018 THITH_05035 ebad4edd083ac87f9fcd0942c38e1542 201 SUPERFAMILY SSF53335 27 186 7.5E-27 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_05035 ebad4edd083ac87f9fcd0942c38e1542 201 Pfam PF08241 Methyltransferase domain 39 127 3.3E-17 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 THITH_11835 8c3255aada9b0dd28fb3f41a9c893a86 229 Gene3D G3DSA:3.40.50.2300 1 127 1.6E-39 T 13-10-2018 THITH_11835 8c3255aada9b0dd28fb3f41a9c893a86 229 TIGRFAM TIGR02154 PhoB: phosphate regulon transcriptional regulatory protein PhoB 2 226 4.7E-106 T 13-10-2018 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB GO:0000156|GO:0000160|GO:0003677|GO:0006817 THITH_11835 8c3255aada9b0dd28fb3f41a9c893a86 229 Pfam PF00072 Response regulator receiver domain 5 117 1.9E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_11835 8c3255aada9b0dd28fb3f41a9c893a86 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 225 5.2E-24 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THITH_11835 8c3255aada9b0dd28fb3f41a9c893a86 229 Gene3D G3DSA:1.10.10.10 128 228 1.8E-35 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_11835 8c3255aada9b0dd28fb3f41a9c893a86 229 SMART SM00862 150 225 3.5E-23 T 13-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 THITH_11835 8c3255aada9b0dd28fb3f41a9c893a86 229 SMART SM00448 3 116 3.6E-44 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_11835 8c3255aada9b0dd28fb3f41a9c893a86 229 SUPERFAMILY SSF46894 127 225 3.12E-29 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THITH_11835 8c3255aada9b0dd28fb3f41a9c893a86 229 SUPERFAMILY SSF52172 3 127 6.4E-44 T 13-10-2018 IPR011006 CheY-like superfamily THITH_00300 4062a4e4c3dae818de1beef3c2da00b5 134 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 127 12.759 T 13-10-2018 IPR022907 VapC family GO:0004540 THITH_00300 4062a4e4c3dae818de1beef3c2da00b5 134 SUPERFAMILY SSF88723 1 130 3.64E-34 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_00300 4062a4e4c3dae818de1beef3c2da00b5 134 Pfam PF01850 PIN domain 3 123 1.3E-16 T 13-10-2018 IPR002716 PIN domain THITH_00300 4062a4e4c3dae818de1beef3c2da00b5 134 Gene3D G3DSA:3.40.50.1010 1 130 3.1E-38 T 13-10-2018 THITH_02655 a46e9e1482c1470179a1461c2432f226 450 Pfam PF13541 Subunit ChlI of Mg-chelatase 343 426 5.3E-8 T 13-10-2018 THITH_02655 a46e9e1482c1470179a1461c2432f226 450 Gene3D G3DSA:3.40.50.300 60 270 1.2E-40 T 13-10-2018 THITH_02655 a46e9e1482c1470179a1461c2432f226 450 SUPERFAMILY SSF52540 65 284 2.8E-50 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_02655 a46e9e1482c1470179a1461c2432f226 450 Hamap MF_01498 DNA repair protein RadA [radA]. 21 448 42.934 T 13-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 THITH_02655 a46e9e1482c1470179a1461c2432f226 450 SMART SM00382 88 241 5.9E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_02655 a46e9e1482c1470179a1461c2432f226 450 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 447 7.5E-185 T 13-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 THITH_02655 a46e9e1482c1470179a1461c2432f226 450 SUPERFAMILY SSF54211 251 449 5.31E-41 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_02655 a46e9e1482c1470179a1461c2432f226 450 Gene3D G3DSA:3.30.230.10 328 450 8.7E-19 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THITH_02655 a46e9e1482c1470179a1461c2432f226 450 PRINTS PR01874 DNA repair protein radA signature 170 194 1.1E-91 T 13-10-2018 THITH_02655 a46e9e1482c1470179a1461c2432f226 450 PRINTS PR01874 DNA repair protein radA signature 209 237 1.1E-91 T 13-10-2018 THITH_02655 a46e9e1482c1470179a1461c2432f226 450 PRINTS PR01874 DNA repair protein radA signature 244 270 1.1E-91 T 13-10-2018 THITH_02655 a46e9e1482c1470179a1461c2432f226 450 PRINTS PR01874 DNA repair protein radA signature 10 34 1.1E-91 T 13-10-2018 THITH_02655 a46e9e1482c1470179a1461c2432f226 450 PRINTS PR01874 DNA repair protein radA signature 80 108 1.1E-91 T 13-10-2018 THITH_02655 a46e9e1482c1470179a1461c2432f226 450 PRINTS PR01874 DNA repair protein radA signature 318 341 1.1E-91 T 13-10-2018 THITH_02655 a46e9e1482c1470179a1461c2432f226 450 PRINTS PR01874 DNA repair protein radA signature 120 137 1.1E-91 T 13-10-2018 THITH_02655 a46e9e1482c1470179a1461c2432f226 450 Pfam PF13481 AAA domain 81 218 2.3E-14 T 13-10-2018 THITH_16085 11bcb0cb1600af7ff7890dfded6257f1 185 ProSitePatterns PS00893 Nudix box signature. 81 102 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THITH_16085 11bcb0cb1600af7ff7890dfded6257f1 185 Gene3D G3DSA:3.90.79.10 8 184 1.7E-44 T 13-10-2018 THITH_16085 11bcb0cb1600af7ff7890dfded6257f1 185 Pfam PF00293 NUDIX domain 49 159 1.2E-12 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 THITH_16085 11bcb0cb1600af7ff7890dfded6257f1 185 SUPERFAMILY SSF55811 9 181 2.84E-35 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 THITH_00155 15e9ab621626d7b3c7223fc458dfd073 237 Pfam PF00072 Response regulator receiver domain 30 141 2.2E-18 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_00155 15e9ab621626d7b3c7223fc458dfd073 237 SMART SM00448 28 141 1.5E-10 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_00155 15e9ab621626d7b3c7223fc458dfd073 237 SUPERFAMILY SSF46894 164 235 1.73E-21 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THITH_00155 15e9ab621626d7b3c7223fc458dfd073 237 SUPERFAMILY SSF52172 26 157 6.69E-22 T 13-10-2018 IPR011006 CheY-like superfamily THITH_00155 15e9ab621626d7b3c7223fc458dfd073 237 Pfam PF00196 Bacterial regulatory proteins, luxR family 176 231 1.1E-17 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_00155 15e9ab621626d7b3c7223fc458dfd073 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 207 4.7E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_00155 15e9ab621626d7b3c7223fc458dfd073 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 207 219 4.7E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_00155 15e9ab621626d7b3c7223fc458dfd073 237 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 191 4.7E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_00155 15e9ab621626d7b3c7223fc458dfd073 237 ProSitePatterns PS00622 LuxR-type HTH domain signature. 191 218 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_00155 15e9ab621626d7b3c7223fc458dfd073 237 Gene3D G3DSA:3.40.50.12740 28 236 1.3E-52 T 13-10-2018 THITH_00155 15e9ab621626d7b3c7223fc458dfd073 237 SMART SM00421 174 231 6.4E-23 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_02905 d08be41088cf16b167c696e0afefc52f 150 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 19 135 1.4E-30 T 13-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 THITH_02905 d08be41088cf16b167c696e0afefc52f 150 SUPERFAMILY SSF54637 15 143 1.11E-38 T 13-10-2018 IPR029069 HotDog domain superfamily THITH_02905 d08be41088cf16b167c696e0afefc52f 150 Pfam PF03061 Thioesterase superfamily 30 113 1.4E-16 T 13-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 THITH_02905 d08be41088cf16b167c696e0afefc52f 150 PIRSF PIRSF003230 8 149 7.7E-40 T 13-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 THITH_02905 d08be41088cf16b167c696e0afefc52f 150 TIGRFAM TIGR02799 thio_ybgC: tol-pal system-associated acyl-CoA thioesterase 16 140 7.9E-49 T 13-10-2018 IPR014166 Tol-Pal system-associated acyl-CoA thioesterase GO:0016790 THITH_02905 d08be41088cf16b167c696e0afefc52f 150 Gene3D G3DSA:3.10.129.10 10 146 1.8E-40 T 13-10-2018 THITH_05685 a553cc246518f157143bacec4ea4dfd2 203 Pfam PF01909 Nucleotidyltransferase domain 102 174 4.5E-6 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THITH_05685 a553cc246518f157143bacec4ea4dfd2 203 SUPERFAMILY SSF81301 101 190 2.1E-16 T 13-10-2018 THITH_05685 a553cc246518f157143bacec4ea4dfd2 203 Gene3D G3DSA:3.30.460.10 94 186 1.9E-14 T 13-10-2018 THITH_05685 a553cc246518f157143bacec4ea4dfd2 203 Gene3D G3DSA:1.10.10.10 3 93 8.5E-8 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_05685 a553cc246518f157143bacec4ea4dfd2 203 SUPERFAMILY SSF46785 12 110 5.07E-11 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_10850 3c74ce1f888869389a12031c8269d583 370 Gene3D G3DSA:2.40.420.20 279 351 2.6E-72 T 13-10-2018 THITH_10850 3c74ce1f888869389a12031c8269d583 370 SUPERFAMILY SSF111369 58 275 1.44E-40 T 13-10-2018 THITH_10850 3c74ce1f888869389a12031c8269d583 370 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 45 353 8.4E-74 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THITH_10850 3c74ce1f888869389a12031c8269d583 370 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 56 268 8.6E-27 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THITH_10850 3c74ce1f888869389a12031c8269d583 370 Gene3D G3DSA:2.40.30.170 57 278 2.6E-72 T 13-10-2018 THITH_10850 3c74ce1f888869389a12031c8269d583 370 Gene3D G3DSA:1.10.287.470 103 162 2.6E-72 T 13-10-2018 THITH_10850 3c74ce1f888869389a12031c8269d583 370 Gene3D G3DSA:2.40.50.100 68 196 2.6E-72 T 13-10-2018 THITH_06430 c6d85066a391663deaf480c9c22dbbcd 312 Pfam PF14715 N-terminal domain of cytochrome oxidase-cbb3, FixP 38 83 7.1E-24 T 13-10-2018 IPR032858 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal THITH_06430 c6d85066a391663deaf480c9c22dbbcd 312 Gene3D G3DSA:1.10.760.10 198 286 1.7E-65 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_06430 c6d85066a391663deaf480c9c22dbbcd 312 SUPERFAMILY SSF46626 226 309 3.64E-22 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_06430 c6d85066a391663deaf480c9c22dbbcd 312 SUPERFAMILY SSF46626 56 225 3.15E-26 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_06430 c6d85066a391663deaf480c9c22dbbcd 312 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 134 217 1.1E-10 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_06430 c6d85066a391663deaf480c9c22dbbcd 312 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 231 306 8.4E-12 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_06430 c6d85066a391663deaf480c9c22dbbcd 312 PIRSF PIRSF000006 1 312 6.1E-96 T 13-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III THITH_06430 c6d85066a391663deaf480c9c22dbbcd 312 Gene3D G3DSA:1.10.760.10 110 309 1.7E-65 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_06430 c6d85066a391663deaf480c9c22dbbcd 312 TIGRFAM TIGR00782 ccoP: cytochrome c oxidase, cbb3-type, subunit III 35 310 3.9E-83 T 13-10-2018 IPR004678 Cytochrome c oxidase cbb3-type, subunit III THITH_06430 c6d85066a391663deaf480c9c22dbbcd 312 Gene3D G3DSA:1.20.58.1490 1 94 5.6E-34 T 13-10-2018 IPR038414 Cbb3-type cytochrome c oxidase subunit CcoP, N-terminal domain superfamily THITH_15440 00f4a2d3d1ad06f8052f5d95440ffca9 224 Pfam PF03692 Putative zinc- or iron-chelating domain 11 86 4.6E-12 T 13-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein THITH_04020 4257b1fe4d3f2b9ad6dac71781eca0bb 333 SUPERFAMILY SSF46626 40 195 1.13E-49 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_04020 4257b1fe4d3f2b9ad6dac71781eca0bb 333 Gene3D G3DSA:1.10.760.10 49 193 4.5E-109 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_04020 4257b1fe4d3f2b9ad6dac71781eca0bb 333 PIRSF PIRSF000294 9 333 6.9E-120 T 13-10-2018 IPR026259 Di-c-type haem protein, MauG/cytochrome c peroxidase GO:0016491|GO:0020037|GO:0055114 THITH_04020 4257b1fe4d3f2b9ad6dac71781eca0bb 333 Pfam PF00034 Cytochrome c 215 320 9.4E-6 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_04020 4257b1fe4d3f2b9ad6dac71781eca0bb 333 Gene3D G3DSA:1.10.760.10 194 322 4.5E-109 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_04020 4257b1fe4d3f2b9ad6dac71781eca0bb 333 SUPERFAMILY SSF46626 194 332 3.48E-40 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_04020 4257b1fe4d3f2b9ad6dac71781eca0bb 333 Pfam PF03150 Di-haem cytochrome c peroxidase 58 206 5.8E-49 T 13-10-2018 IPR004852 Di-haem cytochrome c peroxidase GO:0016491|GO:0055114 THITH_05945 e948474835c5b639d3cc3696dbb8fdb6 73 SUPERFAMILY SSF89447 2 55 1.17E-6 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily THITH_05945 e948474835c5b639d3cc3696dbb8fdb6 73 SMART SM00966 3 46 0.0022 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THITH_16720 02c0c3fdacbc0ea583d70564fcac9115 320 SMART SM00849 61 248 2.6E-9 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_16720 02c0c3fdacbc0ea583d70564fcac9115 320 Pfam PF00753 Metallo-beta-lactamase superfamily 61 248 3.6E-10 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_16720 02c0c3fdacbc0ea583d70564fcac9115 320 Gene3D G3DSA:3.60.15.10 35 276 1.5E-35 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_16720 02c0c3fdacbc0ea583d70564fcac9115 320 SUPERFAMILY SSF56281 12 301 7.14E-43 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_09180 4f2206d61d572b908cfda448e7d53c75 555 SUPERFAMILY SSF52540 305 537 9.46E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_09180 4f2206d61d572b908cfda448e7d53c75 555 Pfam PF12848 ABC transporter 230 303 1.3E-11 T 13-10-2018 IPR032781 ABC-transporter extension domain THITH_09180 4f2206d61d572b908cfda448e7d53c75 555 Gene3D G3DSA:3.40.50.300 1 285 8.3E-83 T 13-10-2018 THITH_09180 4f2206d61d572b908cfda448e7d53c75 555 Pfam PF00005 ABC transporter 340 473 1.0E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_09180 4f2206d61d572b908cfda448e7d53c75 555 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 2 553 4.7E-296 T 13-10-2018 IPR022374 Energy-dependent translational throttle protein EttA GO:0045900 THITH_09180 4f2206d61d572b908cfda448e7d53c75 555 SMART SM00382 348 522 4.7E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_09180 4f2206d61d572b908cfda448e7d53c75 555 SMART SM00382 31 236 9.0E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_09180 4f2206d61d572b908cfda448e7d53c75 555 Gene3D G3DSA:3.40.50.300 286 555 2.5E-74 T 13-10-2018 THITH_09180 4f2206d61d572b908cfda448e7d53c75 555 SUPERFAMILY SSF52540 13 244 2.15E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_09180 4f2206d61d572b908cfda448e7d53c75 555 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_09180 4f2206d61d572b908cfda448e7d53c75 555 Pfam PF00005 ABC transporter 22 191 5.6E-26 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_06635 427f4f942c04e9ee0e9a0b44e25f4a44 299 SUPERFAMILY SSF52402 27 158 3.85E-24 T 13-10-2018 THITH_06635 427f4f942c04e9ee0e9a0b44e25f4a44 299 Gene3D G3DSA:3.40.50.620 25 158 1.5E-22 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_06635 427f4f942c04e9ee0e9a0b44e25f4a44 299 SUPERFAMILY SSF52402 170 298 7.45E-19 T 13-10-2018 THITH_06635 427f4f942c04e9ee0e9a0b44e25f4a44 299 Pfam PF00582 Universal stress protein family 171 296 4.5E-14 T 13-10-2018 IPR006016 UspA THITH_06635 427f4f942c04e9ee0e9a0b44e25f4a44 299 Pfam PF00582 Universal stress protein family 27 156 3.1E-16 T 13-10-2018 IPR006016 UspA THITH_06635 427f4f942c04e9ee0e9a0b44e25f4a44 299 Gene3D G3DSA:3.40.50.620 160 298 2.6E-19 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_06635 427f4f942c04e9ee0e9a0b44e25f4a44 299 PRINTS PR01438 Universal stress protein signature 169 187 3.0E-11 T 13-10-2018 IPR006015 Universal stress protein A THITH_06635 427f4f942c04e9ee0e9a0b44e25f4a44 299 PRINTS PR01438 Universal stress protein signature 256 268 3.0E-11 T 13-10-2018 IPR006015 Universal stress protein A THITH_06635 427f4f942c04e9ee0e9a0b44e25f4a44 299 PRINTS PR01438 Universal stress protein signature 274 296 3.0E-11 T 13-10-2018 IPR006015 Universal stress protein A THITH_13090 334723b10f65e4e35b7a757288da8602 286 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 50 276 9.1E-67 T 13-10-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 THITH_13090 334723b10f65e4e35b7a757288da8602 286 Pfam PF02666 Phosphatidylserine decarboxylase 64 281 1.4E-55 T 13-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 THITH_13090 334723b10f65e4e35b7a757288da8602 286 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 12 284 40.598 T 13-10-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 THITH_04235 2ada1814f03cbf06d14b68fd34759624 331 Pfam PF13469 Sulfotransferase family 14 216 2.2E-21 T 13-10-2018 THITH_04235 2ada1814f03cbf06d14b68fd34759624 331 SUPERFAMILY SSF52540 13 308 5.98E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16800 6fa28a0916f486673930002095ab7ab0 972 SUPERFAMILY SSF53300 11 154 2.74E-20 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily THITH_16800 6fa28a0916f486673930002095ab7ab0 972 SMART SM00327 9 185 3.5E-7 T 13-10-2018 IPR002035 von Willebrand factor, type A THITH_16800 6fa28a0916f486673930002095ab7ab0 972 Gene3D G3DSA:3.40.50.410 11 192 7.6E-26 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily THITH_16800 6fa28a0916f486673930002095ab7ab0 972 Pfam PF13519 von Willebrand factor type A domain 12 124 1.0E-10 T 13-10-2018 IPR002035 von Willebrand factor, type A THITH_06915 770bad6693a2ed658e8769ae5958275b 207 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 8 204 1.7E-65 T 13-10-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004 THITH_06915 770bad6693a2ed658e8769ae5958275b 207 SMART SM00382 30 207 1.7E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_06915 770bad6693a2ed658e8769ae5958275b 207 Gene3D G3DSA:3.40.50.300 3 202 4.2E-42 T 13-10-2018 THITH_06915 770bad6693a2ed658e8769ae5958275b 207 SUPERFAMILY SSF52540 6 198 3.24E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_06915 770bad6693a2ed658e8769ae5958275b 207 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_06915 770bad6693a2ed658e8769ae5958275b 207 Pfam PF00005 ABC transporter 22 162 2.1E-26 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_07095 64abf9bfc4557cc5d6ae339fa8ebf615 242 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 11 231 5.4E-69 T 13-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 THITH_07095 64abf9bfc4557cc5d6ae339fa8ebf615 242 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 12 233 9.1E-67 T 13-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 THITH_07095 64abf9bfc4557cc5d6ae339fa8ebf615 242 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 9 232 43.099 T 13-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 THITH_07095 64abf9bfc4557cc5d6ae339fa8ebf615 242 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 108 115 - T 13-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 THITH_07095 64abf9bfc4557cc5d6ae339fa8ebf615 242 Gene3D G3DSA:3.90.550.10 4 238 3.8E-72 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_07095 64abf9bfc4557cc5d6ae339fa8ebf615 242 SUPERFAMILY SSF53448 10 233 1.46E-56 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_01045 a126109005e989233c8479229c3cf265 85 PIRSF PIRSF003108 1 85 8.4E-30 T 13-10-2018 IPR026262 Antitoxin DinJ GO:0000986|GO:0015643|GO:0044010 THITH_01045 a126109005e989233c8479229c3cf265 85 Gene3D G3DSA:1.10.1220.10 3 52 1.8E-17 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THITH_01045 a126109005e989233c8479229c3cf265 85 Pfam PF04221 RelB antitoxin 6 78 3.3E-21 T 13-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ THITH_01045 a126109005e989233c8479229c3cf265 85 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 1 83 2.3E-23 T 13-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ THITH_13735 27acbb6112c76e7fd2a805628da1bacf 244 Gene3D G3DSA:3.40.50.2000 5 154 6.4E-37 T 13-10-2018 THITH_13735 27acbb6112c76e7fd2a805628da1bacf 244 Pfam PF13692 Glycosyl transferases group 1 25 153 6.7E-24 T 13-10-2018 THITH_13735 27acbb6112c76e7fd2a805628da1bacf 244 SUPERFAMILY SSF53756 4 147 1.73E-38 T 13-10-2018 THITH_11925 3d57467ee926eaf1735d94b8f173e4c4 143 Pfam PF00334 Nucleoside diphosphate kinase 4 137 1.1E-56 T 13-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THITH_11925 3d57467ee926eaf1735d94b8f173e4c4 143 Gene3D G3DSA:3.30.70.141 1 143 3.8E-58 T 13-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THITH_11925 3d57467ee926eaf1735d94b8f173e4c4 143 SMART SM00562 3 140 2.4E-88 T 13-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THITH_11925 3d57467ee926eaf1735d94b8f173e4c4 143 SUPERFAMILY SSF54919 3 140 9.17E-59 T 13-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THITH_11925 3d57467ee926eaf1735d94b8f173e4c4 143 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 3 138 35.99 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THITH_11925 3d57467ee926eaf1735d94b8f173e4c4 143 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 13-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THITH_11925 3d57467ee926eaf1735d94b8f173e4c4 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 4.7E-40 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THITH_11925 3d57467ee926eaf1735d94b8f173e4c4 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 70 87 4.7E-40 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THITH_11925 3d57467ee926eaf1735d94b8f173e4c4 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 50 69 4.7E-40 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THITH_11925 3d57467ee926eaf1735d94b8f173e4c4 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 6 28 4.7E-40 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THITH_11925 3d57467ee926eaf1735d94b8f173e4c4 143 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 4.7E-40 T 13-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 THITH_16815 d13e55ad9805f5e2c014e7bff79a7373 255 PRINTS PR00334 HMW kininogen signature 182 204 1.0E-8 T 13-10-2018 IPR002395 HMW kininogen Reactome: R-HSA-114608|Reactome: R-HSA-140837|Reactome: R-HSA-375276|Reactome: R-HSA-381426|Reactome: R-HSA-416476|Reactome: R-HSA-418594|Reactome: R-HSA-8957275 THITH_16815 d13e55ad9805f5e2c014e7bff79a7373 255 PRINTS PR00334 HMW kininogen signature 150 173 1.0E-8 T 13-10-2018 IPR002395 HMW kininogen Reactome: R-HSA-114608|Reactome: R-HSA-140837|Reactome: R-HSA-375276|Reactome: R-HSA-381426|Reactome: R-HSA-416476|Reactome: R-HSA-418594|Reactome: R-HSA-8957275 THITH_16815 d13e55ad9805f5e2c014e7bff79a7373 255 PRINTS PR00334 HMW kininogen signature 125 146 1.0E-8 T 13-10-2018 IPR002395 HMW kininogen Reactome: R-HSA-114608|Reactome: R-HSA-140837|Reactome: R-HSA-375276|Reactome: R-HSA-381426|Reactome: R-HSA-416476|Reactome: R-HSA-418594|Reactome: R-HSA-8957275 THITH_16815 d13e55ad9805f5e2c014e7bff79a7373 255 Pfam PF10986 Protein of unknown function (DUF2796) 32 250 1.2E-42 T 13-10-2018 IPR021253 Protein of unknown function DUF2796 THITH_02420 a4861a59c962b7ebd955afc389f54ef6 181 Pfam PF13242 HAD-hyrolase-like 100 145 3.0E-13 T 13-10-2018 THITH_02420 a4861a59c962b7ebd955afc389f54ef6 181 Gene3D G3DSA:3.40.50.1000 1 171 2.0E-55 T 13-10-2018 IPR023214 HAD superfamily THITH_02420 a4861a59c962b7ebd955afc389f54ef6 181 PIRSF PIRSF004682 1 173 1.1E-55 T 13-10-2018 IPR004446 D,D-heptose 1,7-bisphosphate phosphatase GO:0005975|GO:0016791 THITH_02420 a4861a59c962b7ebd955afc389f54ef6 181 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 4 147 1.9E-34 T 13-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 THITH_02420 a4861a59c962b7ebd955afc389f54ef6 181 TIGRFAM TIGR01656 Histidinol-ppas: histidinol-phosphate phosphatase domain 5 143 9.9E-44 T 13-10-2018 IPR006543 Histidinol-phosphate phosphatase GO:0016791 THITH_02420 a4861a59c962b7ebd955afc389f54ef6 181 SUPERFAMILY SSF56784 2 170 3.94E-49 T 13-10-2018 IPR036412 HAD-like superfamily THITH_06740 44423e1ac392a0fcd5973aae38446ff5 278 Pfam PF01040 UbiA prenyltransferase family 11 249 6.9E-34 T 13-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 THITH_06740 44423e1ac392a0fcd5973aae38446ff5 278 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 2 269 1.8E-56 T 13-10-2018 THITH_06740 44423e1ac392a0fcd5973aae38446ff5 278 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 1 275 16.902 T 13-10-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 THITH_06740 44423e1ac392a0fcd5973aae38446ff5 278 PIRSF PIRSF005355 1 277 4.8E-66 T 13-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 THITH_06740 44423e1ac392a0fcd5973aae38446ff5 278 Gene3D G3DSA:1.10.357.140 8 137 7.6E-8 T 13-10-2018 THITH_16370 707b39fe833b71f90135b32e1bb50cb6 307 SUPERFAMILY SSF56327 144 305 1.3E-44 T 13-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 THITH_16370 707b39fe833b71f90135b32e1bb50cb6 307 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 146 305 1.2E-25 T 13-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 THITH_16370 707b39fe833b71f90135b32e1bb50cb6 307 PRINTS PR00086 L-lactate dehydrogenase signature 3 27 1.0E-27 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THITH_16370 707b39fe833b71f90135b32e1bb50cb6 307 PRINTS PR00086 L-lactate dehydrogenase signature 116 136 1.0E-27 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THITH_16370 707b39fe833b71f90135b32e1bb50cb6 307 PRINTS PR00086 L-lactate dehydrogenase signature 28 52 1.0E-27 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THITH_16370 707b39fe833b71f90135b32e1bb50cb6 307 PRINTS PR00086 L-lactate dehydrogenase signature 140 158 1.0E-27 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THITH_16370 707b39fe833b71f90135b32e1bb50cb6 307 PRINTS PR00086 L-lactate dehydrogenase signature 170 183 1.0E-27 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THITH_16370 707b39fe833b71f90135b32e1bb50cb6 307 Hamap MF_00487 Malate dehydrogenase [mdh]. 1 307 40.162 T 13-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 THITH_16370 707b39fe833b71f90135b32e1bb50cb6 307 SUPERFAMILY SSF51735 2 142 4.96E-43 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_16370 707b39fe833b71f90135b32e1bb50cb6 307 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 3 142 3.3E-37 T 13-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 THITH_16370 707b39fe833b71f90135b32e1bb50cb6 307 PIRSF PIRSF000102 1 307 8.7E-91 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THITH_16370 707b39fe833b71f90135b32e1bb50cb6 307 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 3 305 5.6E-109 T 13-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 THITH_16370 707b39fe833b71f90135b32e1bb50cb6 307 Gene3D G3DSA:3.90.110.10 145 307 6.9E-49 T 13-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 THITH_16370 707b39fe833b71f90135b32e1bb50cb6 307 Gene3D G3DSA:3.40.50.720 2 144 1.4E-46 T 13-10-2018 THITH_09000 5b4a47fe75016851d9d93e2a2528de06 103 Gene3D G3DSA:1.10.760.10 23 103 2.6E-24 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_09000 5b4a47fe75016851d9d93e2a2528de06 103 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 25 100 2.2E-10 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_09000 5b4a47fe75016851d9d93e2a2528de06 103 SUPERFAMILY SSF46626 14 103 5.56E-23 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_10570 e2aab5027fa9b3ad0aac1aa7f5546022 264 Gene3D G3DSA:3.40.50.150 27 257 5.6E-33 T 13-10-2018 THITH_10570 e2aab5027fa9b3ad0aac1aa7f5546022 264 Pfam PF13649 Methyltransferase domain 45 140 4.1E-13 T 13-10-2018 THITH_10570 e2aab5027fa9b3ad0aac1aa7f5546022 264 SUPERFAMILY SSF53335 5 255 1.96E-33 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_01530 74312daa82ae721b56e7151ff9c5afb3 409 Gene3D G3DSA:1.10.150.130 89 206 2.3E-28 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal THITH_01530 74312daa82ae721b56e7151ff9c5afb3 409 Gene3D G3DSA:1.10.443.10 210 384 5.1E-15 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 THITH_01530 74312daa82ae721b56e7151ff9c5afb3 409 Pfam PF00589 Phage integrase family 210 370 4.9E-14 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THITH_01530 74312daa82ae721b56e7151ff9c5afb3 409 SUPERFAMILY SSF56349 99 381 1.62E-57 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THITH_01530 74312daa82ae721b56e7151ff9c5afb3 409 Pfam PF13356 Arm DNA-binding domain 3 88 5.8E-17 T 13-10-2018 IPR025166 Integrase, DNA-binding domain THITH_01530 74312daa82ae721b56e7151ff9c5afb3 409 Gene3D G3DSA:3.30.160.390 1 88 1.3E-28 T 13-10-2018 IPR038488 Integrase, DNA-binding domain superfamily THITH_02815 1a64746b36c706382c9be5ddb88d42a2 97 Pfam PF00708 Acylphosphatase 12 94 6.9E-24 T 13-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THITH_02815 1a64746b36c706382c9be5ddb88d42a2 97 ProSitePatterns PS00150 Acylphosphatase signature 1. 15 25 - T 13-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THITH_02815 1a64746b36c706382c9be5ddb88d42a2 97 Gene3D G3DSA:3.30.70.100 1 97 5.3E-27 T 13-10-2018 THITH_02815 1a64746b36c706382c9be5ddb88d42a2 97 PRINTS PR00112 Acylphosphatase signature 10 25 7.1E-5 T 13-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THITH_02815 1a64746b36c706382c9be5ddb88d42a2 97 PRINTS PR00112 Acylphosphatase signature 31 56 7.1E-5 T 13-10-2018 IPR020456 Acylphosphatase GO:0003998 KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THITH_02815 1a64746b36c706382c9be5ddb88d42a2 97 SUPERFAMILY SSF54975 9 96 2.4E-26 T 13-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THITH_02815 1a64746b36c706382c9be5ddb88d42a2 97 ProSitePatterns PS00151 Acylphosphatase signature 2. 39 55 - T 13-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 THITH_00605 25147a780d04393794c92198a400054a 443 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 3 438 9.5E-78 T 13-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 THITH_00605 25147a780d04393794c92198a400054a 443 Pfam PF01593 Flavin containing amine oxidoreductase 10 439 1.5E-45 T 13-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 THITH_00605 25147a780d04393794c92198a400054a 443 Gene3D G3DSA:1.10.3110.10 98 196 2.5E-126 T 13-10-2018 THITH_00605 25147a780d04393794c92198a400054a 443 Gene3D G3DSA:3.50.50.60 4 434 2.5E-126 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_00605 25147a780d04393794c92198a400054a 443 SUPERFAMILY SSF51905 1 440 5.83E-52 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_00605 25147a780d04393794c92198a400054a 443 SUPERFAMILY SSF54373 285 390 3.73E-25 T 13-10-2018 THITH_00605 25147a780d04393794c92198a400054a 443 Gene3D G3DSA:3.90.660.20 40 391 2.5E-126 T 13-10-2018 THITH_00525 3d9441cbfc8277038ae02f1a6ca873f7 184 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 177 41.592 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 THITH_00525 3d9441cbfc8277038ae02f1a6ca873f7 184 PIRSF PIRSF039093 1 180 3.2E-88 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 THITH_00525 3d9441cbfc8277038ae02f1a6ca873f7 184 Pfam PF00227 Proteasome subunit 5 175 2.5E-23 T 13-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 THITH_00525 3d9441cbfc8277038ae02f1a6ca873f7 184 SUPERFAMILY SSF56235 3 177 5.29E-60 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_00525 3d9441cbfc8277038ae02f1a6ca873f7 184 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 177 3.1E-85 T 13-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 THITH_00525 3d9441cbfc8277038ae02f1a6ca873f7 184 Gene3D G3DSA:3.60.20.10 2 178 7.0E-67 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_06045 c3f70c067e1f7f4b7bc76549432895d7 113 SUPERFAMILY SSF46785 37 99 8.11E-7 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_03910 b5028e512dfbec7f9b543dae00558086 397 Hamap MF_02056 O-succinylhomoserine sulfhydrylase [metZ]. 13 394 54.692 T 13-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 THITH_03910 b5028e512dfbec7f9b543dae00558086 397 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 203 217 - T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 THITH_03910 b5028e512dfbec7f9b543dae00558086 397 Gene3D G3DSA:3.40.640.10 7 259 5.9E-87 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_03910 b5028e512dfbec7f9b543dae00558086 397 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 12 393 1.8E-134 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 THITH_03910 b5028e512dfbec7f9b543dae00558086 397 Gene3D G3DSA:3.90.1150.10 262 397 1.0E-49 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_03910 b5028e512dfbec7f9b543dae00558086 397 SUPERFAMILY SSF53383 32 395 6.92E-118 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_03910 b5028e512dfbec7f9b543dae00558086 397 TIGRFAM TIGR01325 O_suc_HS_sulf: O-succinylhomoserine sulfhydrylase 12 393 6.2E-175 T 13-10-2018 IPR006234 O-succinylhomoserine sulfhydrylase GO:0071268 THITH_03910 b5028e512dfbec7f9b543dae00558086 397 PIRSF PIRSF001434 1 397 5.1E-129 T 13-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 THITH_14410 717743ca7e5d9360fd2eb077eed3b3f1 315 Gene3D G3DSA:3.20.20.70 123 315 1.2E-38 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_14410 717743ca7e5d9360fd2eb077eed3b3f1 315 SUPERFAMILY SSF51391 112 313 5.1E-40 T 13-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THITH_14410 717743ca7e5d9360fd2eb077eed3b3f1 315 ProSitePatterns PS00893 Nudix box signature. 35 56 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THITH_14410 717743ca7e5d9360fd2eb077eed3b3f1 315 Pfam PF02581 Thiamine monophosphate synthase 129 308 1.9E-33 T 13-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 THITH_14410 717743ca7e5d9360fd2eb077eed3b3f1 315 Pfam PF14815 NUDIX domain 4 121 1.8E-19 T 13-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 THITH_14410 717743ca7e5d9360fd2eb077eed3b3f1 315 Gene3D G3DSA:3.90.79.10 1 122 5.2E-32 T 13-10-2018 THITH_14410 717743ca7e5d9360fd2eb077eed3b3f1 315 SUPERFAMILY SSF55811 2 123 1.49E-32 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 THITH_10335 d805530f7bd276a865b77bfcd5654789 100 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 91 2.9E-11 T 13-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like THITH_10335 d805530f7bd276a865b77bfcd5654789 100 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 100 15.036 T 13-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 THITH_06625 0f29df6f6b19025f8444360907a25c1f 695 Gene3D G3DSA:3.30.750.24 559 690 8.5E-27 T 13-10-2018 IPR036513 STAS domain superfamily THITH_06625 0f29df6f6b19025f8444360907a25c1f 695 Pfam PF00916 Sulfate permease family 22 248 5.3E-51 T 13-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 THITH_06625 0f29df6f6b19025f8444360907a25c1f 695 Pfam PF00916 Sulfate permease family 353 515 2.3E-49 T 13-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 THITH_06625 0f29df6f6b19025f8444360907a25c1f 695 SUPERFAMILY SSF52091 572 680 5.89E-19 T 13-10-2018 IPR036513 STAS domain superfamily THITH_06625 0f29df6f6b19025f8444360907a25c1f 695 Pfam PF01740 STAS domain 572 673 3.2E-18 T 13-10-2018 IPR002645 STAS domain THITH_10520 d0c1ee1415eca6215bb26ac7c09779f9 220 SUPERFAMILY SSF52266 29 208 1.13E-44 T 13-10-2018 THITH_10520 d0c1ee1415eca6215bb26ac7c09779f9 220 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 34 190 1.2E-21 T 13-10-2018 IPR013830 SGNH hydrolase-type esterase domain THITH_10520 d0c1ee1415eca6215bb26ac7c09779f9 220 Gene3D G3DSA:3.40.50.1110 30 214 1.2E-63 T 13-10-2018 IPR036514 SGNH hydrolase superfamily THITH_13280 09fde806291cf4ec33805b290171dc70 102 SUPERFAMILY SSF46626 31 100 3.1E-17 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_13280 09fde806291cf4ec33805b290171dc70 102 Pfam PF00034 Cytochrome c 33 99 1.2E-4 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_13280 09fde806291cf4ec33805b290171dc70 102 Gene3D G3DSA:1.10.760.10 30 102 4.3E-20 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_14630 035ca5b0896cba267e4b91fd99883eed 323 Gene3D G3DSA:1.20.1420.30 35 310 6.9E-89 T 13-10-2018 THITH_14630 035ca5b0896cba267e4b91fd99883eed 323 Gene3D G3DSA:1.20.58.1130 10 206 6.9E-89 T 13-10-2018 THITH_14630 035ca5b0896cba267e4b91fd99883eed 323 Pfam PF01699 Sodium/calcium exchanger protein 6 138 4.9E-23 T 13-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 THITH_14630 035ca5b0896cba267e4b91fd99883eed 323 Pfam PF01699 Sodium/calcium exchanger protein 175 316 2.6E-32 T 13-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 THITH_14630 035ca5b0896cba267e4b91fd99883eed 323 TIGRFAM TIGR00367 TIGR00367: K+-dependent Na+/Ca+ exchanger homolog 6 311 1.4E-76 T 13-10-2018 IPR004481 Sodium/potassium/calcium exchanger Reactome: R-HSA-425561 THITH_16875 a2c5a844630cee17057228de3c84c177 261 SMART SM00849 42 230 3.9E-14 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_16875 a2c5a844630cee17057228de3c84c177 261 Pfam PF00753 Metallo-beta-lactamase superfamily 41 228 2.5E-7 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_16875 a2c5a844630cee17057228de3c84c177 261 SUPERFAMILY SSF56281 30 250 7.4E-29 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_16875 a2c5a844630cee17057228de3c84c177 261 Gene3D G3DSA:3.60.15.10 14 245 8.5E-37 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_04820 86004327369a48d12566b3b206a597cb 279 Gene3D G3DSA:3.10.350.10 35 78 2.3E-12 T 13-10-2018 IPR036779 LysM domain superfamily THITH_04820 86004327369a48d12566b3b206a597cb 279 SUPERFAMILY SSF51261 39 276 5.02E-40 T 13-10-2018 IPR011055 Duplicated hybrid motif THITH_04820 86004327369a48d12566b3b206a597cb 279 Pfam PF01551 Peptidase family M23 179 272 4.5E-25 T 13-10-2018 IPR016047 Peptidase M23 THITH_04820 86004327369a48d12566b3b206a597cb 279 Gene3D G3DSA:2.70.70.10 149 276 3.5E-32 T 13-10-2018 IPR011055 Duplicated hybrid motif THITH_04820 86004327369a48d12566b3b206a597cb 279 Pfam PF01476 LysM domain 37 79 1.5E-11 T 13-10-2018 IPR018392 LysM domain THITH_04820 86004327369a48d12566b3b206a597cb 279 SMART SM00257 36 80 5.9E-9 T 13-10-2018 IPR018392 LysM domain THITH_15300 c83872b04c83bb21aef2a62a8839a38d 115 Pfam PF03091 CutA1 divalent ion tolerance protein 16 112 2.3E-34 T 13-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 THITH_15300 c83872b04c83bb21aef2a62a8839a38d 115 Gene3D G3DSA:3.30.70.120 4 115 9.1E-37 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THITH_15300 c83872b04c83bb21aef2a62a8839a38d 115 SUPERFAMILY SSF54913 12 114 2.82E-36 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THITH_00305 d63753de660432c53d5b0dd57a8ccbb5 162 Pfam PF11848 Domain of unknown function (DUF3368) 118 160 3.7E-13 T 13-10-2018 IPR021799 Protein of unknown function DUF3368 THITH_11850 7a332d662687acdd00b856abbd25072b 338 SUPERFAMILY SSF53187 22 321 1.09E-62 T 13-10-2018 THITH_11850 7a332d662687acdd00b856abbd25072b 338 Gene3D G3DSA:3.40.630.10 11 319 3.0E-57 T 13-10-2018 THITH_11850 7a332d662687acdd00b856abbd25072b 338 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 23 312 2.9E-24 T 13-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 THITH_08390 4948e8e0b9bab334ff089e0495e625f2 440 Gene3D G3DSA:3.60.120.10 4 440 1.9E-104 T 13-10-2018 IPR005801 ADC synthase GO:0009058 THITH_08390 4948e8e0b9bab334ff089e0495e625f2 440 SUPERFAMILY SSF56322 16 439 1.11E-83 T 13-10-2018 IPR005801 ADC synthase GO:0009058 THITH_08390 4948e8e0b9bab334ff089e0495e625f2 440 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 89 437 8.2E-86 T 13-10-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 THITH_08390 4948e8e0b9bab334ff089e0495e625f2 440 Pfam PF00425 chorismate binding enzyme 181 430 1.0E-63 T 13-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal THITH_13050 ae08154e99bcb7efc1fddafe8240ee40 99 Gene3D G3DSA:3.30.70.100 1 96 2.9E-32 T 13-10-2018 THITH_13050 ae08154e99bcb7efc1fddafe8240ee40 99 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 5.8E-16 T 13-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain THITH_13050 ae08154e99bcb7efc1fddafe8240ee40 99 SUPERFAMILY SSF54909 1 87 1.7E-26 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel THITH_01015 6daa202cb62ce6c2a9ad40c4ab870757 619 SUPERFAMILY SSF52540 342 583 7.37E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01015 6daa202cb62ce6c2a9ad40c4ab870757 619 SUPERFAMILY SSF52540 1 244 6.15E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01015 6daa202cb62ce6c2a9ad40c4ab870757 619 Pfam PF00005 ABC transporter 20 176 2.0E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_01015 6daa202cb62ce6c2a9ad40c4ab870757 619 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_01015 6daa202cb62ce6c2a9ad40c4ab870757 619 SMART SM00382 29 223 1.5E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_01015 6daa202cb62ce6c2a9ad40c4ab870757 619 SMART SM00382 366 561 6.3E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_01015 6daa202cb62ce6c2a9ad40c4ab870757 619 Pfam PF00005 ABC transporter 358 512 5.7E-24 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_01015 6daa202cb62ce6c2a9ad40c4ab870757 619 Gene3D G3DSA:3.40.50.300 339 617 3.8E-73 T 13-10-2018 THITH_01015 6daa202cb62ce6c2a9ad40c4ab870757 619 Gene3D G3DSA:3.40.50.300 1 337 1.2E-79 T 13-10-2018 THITH_01015 6daa202cb62ce6c2a9ad40c4ab870757 619 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 563 586 6.1E-4 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THITH_01015 6daa202cb62ce6c2a9ad40c4ab870757 619 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 227 316 5.2E-12 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THITH_13535 60228ec7ff79e97c8f4a193cac967b7b 653 Gene3D G3DSA:3.90.400.10 184 259 4.7E-196 T 13-10-2018 THITH_13535 60228ec7ff79e97c8f4a193cac967b7b 653 Gene3D G3DSA:1.10.1740.10 4 94 3.2E-18 T 13-10-2018 THITH_13535 60228ec7ff79e97c8f4a193cac967b7b 653 Gene3D G3DSA:2.60.40.1180 567 653 1.9E-9 T 13-10-2018 IPR013780 Glycosyl hydrolase, all-beta THITH_13535 60228ec7ff79e97c8f4a193cac967b7b 653 SUPERFAMILY SSF51011 571 649 3.92E-12 T 13-10-2018 THITH_13535 60228ec7ff79e97c8f4a193cac967b7b 653 SUPERFAMILY SSF51445 19 563 1.01E-116 T 13-10-2018 IPR017853 Glycoside hydrolase superfamily THITH_13535 60228ec7ff79e97c8f4a193cac967b7b 653 Pfam PF00128 Alpha amylase, catalytic domain 107 338 4.5E-39 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THITH_13535 60228ec7ff79e97c8f4a193cac967b7b 653 Pfam PF16657 Maltogenic Amylase, C-terminal domain 569 648 2.8E-7 T 13-10-2018 IPR032091 Maltogenic Amylase, C-terminal THITH_13535 60228ec7ff79e97c8f4a193cac967b7b 653 Gene3D G3DSA:3.20.20.80 99 558 4.7E-196 T 13-10-2018 THITH_13535 60228ec7ff79e97c8f4a193cac967b7b 653 SMART SM00642 99 556 7.2E-28 T 13-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 THITH_16660 e5937499a69a396481e89f26135b87f0 611 Gene3D G3DSA:3.40.50.300 362 544 3.1E-41 T 13-10-2018 THITH_16660 e5937499a69a396481e89f26135b87f0 611 Gene3D G3DSA:3.40.50.300 136 307 4.5E-25 T 13-10-2018 THITH_16660 e5937499a69a396481e89f26135b87f0 611 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 164 290 3.8E-14 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THITH_16660 e5937499a69a396481e89f26135b87f0 611 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 405 527 5.6E-32 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THITH_16660 e5937499a69a396481e89f26135b87f0 611 SUPERFAMILY SSF52540 135 307 1.41E-26 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16660 e5937499a69a396481e89f26135b87f0 611 SUPERFAMILY SSF52540 367 582 5.21E-39 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16660 e5937499a69a396481e89f26135b87f0 611 SMART SM00382 401 530 7.5E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_16660 e5937499a69a396481e89f26135b87f0 611 SMART SM00382 160 293 2.9E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_10745 e58df1e431dd54a853b2ceaae0f6bc02 430 SUPERFAMILY SSF53244 288 421 8.79E-23 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THITH_10745 e58df1e431dd54a853b2ceaae0f6bc02 430 Gene3D G3DSA:3.40.1190.10 1 287 6.3E-81 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THITH_10745 e58df1e431dd54a853b2ceaae0f6bc02 430 Gene3D G3DSA:3.90.190.20 288 424 6.8E-25 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THITH_10745 e58df1e431dd54a853b2ceaae0f6bc02 430 SUPERFAMILY SSF53623 4 284 1.68E-78 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THITH_10745 e58df1e431dd54a853b2ceaae0f6bc02 430 PIRSF PIRSF001563 1 423 5.0E-92 T 13-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 THITH_10745 e58df1e431dd54a853b2ceaae0f6bc02 430 Pfam PF08245 Mur ligase middle domain 48 199 4.3E-7 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 THITH_10745 e58df1e431dd54a853b2ceaae0f6bc02 430 TIGRFAM TIGR01499 folC: bifunctional protein FolC 25 419 4.5E-84 T 13-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 THITH_13740 346aa64829132ef3d9d9d5f9a00243c6 1370 Gene3D G3DSA:3.40.50.300 1127 1326 7.5E-74 T 13-10-2018 THITH_13740 346aa64829132ef3d9d9d5f9a00243c6 1370 Pfam PF00271 Helicase conserved C-terminal domain 1201 1312 1.6E-18 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_13740 346aa64829132ef3d9d9d5f9a00243c6 1370 Gene3D G3DSA:1.20.120.850 1142 1359 7.5E-74 T 13-10-2018 THITH_13740 346aa64829132ef3d9d9d5f9a00243c6 1370 Gene3D G3DSA:3.40.50.10810 913 1121 2.0E-60 T 13-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily THITH_13740 346aa64829132ef3d9d9d5f9a00243c6 1370 SMART SM00487 908 1092 4.3E-24 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_13740 346aa64829132ef3d9d9d5f9a00243c6 1370 SUPERFAMILY SSF52540 1122 1363 9.31E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13740 346aa64829132ef3d9d9d5f9a00243c6 1370 Pfam PF00176 SNF2 family N-terminal domain 931 1191 4.4E-46 T 13-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 THITH_13740 346aa64829132ef3d9d9d5f9a00243c6 1370 SUPERFAMILY SSF52540 900 1120 1.65E-52 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13740 346aa64829132ef3d9d9d5f9a00243c6 1370 SMART SM00490 1230 1312 5.4E-21 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_05735 65ed2c86739c28ceab3209feb0df22cc 70 SUPERFAMILY SSF143100 4 65 1.7E-22 T 13-10-2018 IPR035069 TTHA1013/TTHA0281-like THITH_05735 65ed2c86739c28ceab3209feb0df22cc 70 Gene3D G3DSA:3.30.160.250 3 69 1.6E-17 T 13-10-2018 THITH_05735 65ed2c86739c28ceab3209feb0df22cc 70 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 7 64 5.8E-11 T 13-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system THITH_06420 0d3785602f4164952fc3b851666c2278 168 Pfam PF05751 FixH 13 154 3.8E-30 T 13-10-2018 IPR008620 Nitrogen fixation protein FixH THITH_15640 557424b2510f381300f7e764da2e68eb 220 Pfam PF00156 Phosphoribosyl transferase domain 121 218 8.5E-9 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 THITH_15640 557424b2510f381300f7e764da2e68eb 220 Gene3D G3DSA:3.40.50.2020 105 220 5.1E-19 T 13-10-2018 THITH_15640 557424b2510f381300f7e764da2e68eb 220 SUPERFAMILY SSF53271 45 218 1.14E-33 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like THITH_02545 0826893dff227916e21b4a04b1f079cc 124 Pfam PF01521 Iron-sulphur cluster biosynthesis 19 119 1.0E-20 T 13-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THITH_02545 0826893dff227916e21b4a04b1f079cc 124 SUPERFAMILY SSF89360 17 110 1.24E-31 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 THITH_02545 0826893dff227916e21b4a04b1f079cc 124 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 20 123 8.8E-39 T 13-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 THITH_02545 0826893dff227916e21b4a04b1f079cc 124 Gene3D G3DSA:2.60.300.12 19 124 6.7E-34 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 THITH_02545 0826893dff227916e21b4a04b1f079cc 124 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 105 122 - T 13-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 THITH_02545 0826893dff227916e21b4a04b1f079cc 124 Hamap MF_01380 Iron-sulfur cluster insertion protein ErpA [erpA]. 5 124 36.81 T 13-10-2018 IPR023063 FeS cluster insertion protein ErpA GO:0097428 THITH_01975 690fe0e8296dda3522362e281352ae61 199 Pfam PF05036 Sporulation related domain 122 191 2.9E-13 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 THITH_01975 690fe0e8296dda3522362e281352ae61 199 SUPERFAMILY SSF110997 121 194 2.09E-16 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 THITH_01975 690fe0e8296dda3522362e281352ae61 199 Gene3D G3DSA:3.30.70.1070 118 199 3.5E-18 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 THITH_10465 35cd2b3f835a6a09e6b09ff346a60d85 261 Hamap MF_01974 Methionine aminopeptidase [map]. 3 250 42.495 T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 THITH_10465 35cd2b3f835a6a09e6b09ff346a60d85 261 SUPERFAMILY SSF55920 4 249 4.06E-94 T 13-10-2018 IPR036005 Creatinase/aminopeptidase-like THITH_10465 35cd2b3f835a6a09e6b09ff346a60d85 261 Pfam PF00557 Metallopeptidase family M24 12 241 2.5E-56 T 13-10-2018 IPR000994 Peptidase M24 THITH_10465 35cd2b3f835a6a09e6b09ff346a60d85 261 PRINTS PR00599 Methionine aminopeptidase-1 signature 161 173 9.4E-22 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 THITH_10465 35cd2b3f835a6a09e6b09ff346a60d85 261 PRINTS PR00599 Methionine aminopeptidase-1 signature 192 204 9.4E-22 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 THITH_10465 35cd2b3f835a6a09e6b09ff346a60d85 261 PRINTS PR00599 Methionine aminopeptidase-1 signature 69 82 9.4E-22 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 THITH_10465 35cd2b3f835a6a09e6b09ff346a60d85 261 PRINTS PR00599 Methionine aminopeptidase-1 signature 91 107 9.4E-22 T 13-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 THITH_10465 35cd2b3f835a6a09e6b09ff346a60d85 261 Gene3D G3DSA:3.90.230.10 1 259 3.0E-117 T 13-10-2018 THITH_10465 35cd2b3f835a6a09e6b09ff346a60d85 261 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 4 249 1.5E-99 T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 THITH_10465 35cd2b3f835a6a09e6b09ff346a60d85 261 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 167 185 - T 13-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 THITH_11790 d56a534ecdd6e53cccd801fd3d4ac417 242 SUPERFAMILY SSF109755 13 233 5.76E-66 T 13-10-2018 THITH_11790 d56a534ecdd6e53cccd801fd3d4ac417 242 Gene3D G3DSA:1.20.58.220 122 240 5.5E-32 T 13-10-2018 IPR038078 PhoU-like domain superfamily THITH_11790 d56a534ecdd6e53cccd801fd3d4ac417 242 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 13 224 2.7E-69 T 13-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 THITH_11790 d56a534ecdd6e53cccd801fd3d4ac417 242 Gene3D G3DSA:1.20.58.220 1 121 3.6E-40 T 13-10-2018 IPR038078 PhoU-like domain superfamily THITH_11790 d56a534ecdd6e53cccd801fd3d4ac417 242 Pfam PF01895 PhoU domain 131 215 8.1E-16 T 13-10-2018 IPR026022 PhoU domain THITH_11790 d56a534ecdd6e53cccd801fd3d4ac417 242 Pfam PF01895 PhoU domain 27 112 7.5E-22 T 13-10-2018 IPR026022 PhoU domain THITH_11790 d56a534ecdd6e53cccd801fd3d4ac417 242 PIRSF PIRSF003107 8 229 9.6E-67 T 13-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 THITH_10445 bd26bb9721d3ed9f6cf52a95ca3da568 185 SUPERFAMILY SSF55194 1 185 5.76E-72 T 13-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 THITH_10445 bd26bb9721d3ed9f6cf52a95ca3da568 185 Gene3D G3DSA:1.10.132.20 12 182 1.0E-67 T 13-10-2018 THITH_10445 bd26bb9721d3ed9f6cf52a95ca3da568 185 Gene3D G3DSA:3.30.1360.40 31 105 1.0E-67 T 13-10-2018 THITH_10445 bd26bb9721d3ed9f6cf52a95ca3da568 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 28.055 T 13-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 THITH_10445 bd26bb9721d3ed9f6cf52a95ca3da568 185 Pfam PF01765 Ribosome recycling factor 20 183 3.9E-63 T 13-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 THITH_10445 bd26bb9721d3ed9f6cf52a95ca3da568 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 11 185 1.9E-74 T 13-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 THITH_14085 7cec2c8902b778a41b6b2e9fd46d40e6 184 SUPERFAMILY SSF90257 43 142 6.02E-6 T 13-10-2018 THITH_14085 7cec2c8902b778a41b6b2e9fd46d40e6 184 Gene3D G3DSA:1.20.5.340 34 144 3.0E-6 T 13-10-2018 THITH_15930 39c365ddf9e3750082b02c0b41699272 354 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 139 150 - T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 THITH_15930 39c365ddf9e3750082b02c0b41699272 354 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 73 85 - T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 THITH_15930 39c365ddf9e3750082b02c0b41699272 354 Pfam PF01116 Fructose-bisphosphate aldolase class-II 5 327 1.3E-90 T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 THITH_15930 39c365ddf9e3750082b02c0b41699272 354 Gene3D G3DSA:3.20.20.70 1 354 3.0E-149 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_15930 39c365ddf9e3750082b02c0b41699272 354 SUPERFAMILY SSF51569 3 328 1.2E-105 T 13-10-2018 THITH_15930 39c365ddf9e3750082b02c0b41699272 354 PIRSF PIRSF001359 1 329 2.2E-80 T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 THITH_15930 39c365ddf9e3750082b02c0b41699272 354 TIGRFAM TIGR01521 FruBisAldo_II_B: fructose-bisphosphate aldolase, class II, Calvin cycle subtype 3 349 3.2E-194 T 13-10-2018 IPR006412 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 THITH_15930 39c365ddf9e3750082b02c0b41699272 354 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 328 9.0E-96 T 13-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 THITH_09490 75af32a4a04c5ffa135d9d7692951e82 437 SUPERFAMILY SSF53720 1 428 2.75E-117 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 THITH_09490 75af32a4a04c5ffa135d9d7692951e82 437 Gene3D G3DSA:3.40.605.10 1 425 2.2E-123 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 THITH_09490 75af32a4a04c5ffa135d9d7692951e82 437 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 228 239 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 THITH_09490 75af32a4a04c5ffa135d9d7692951e82 437 Pfam PF00171 Aldehyde dehydrogenase family 1 428 1.5E-121 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 THITH_09490 75af32a4a04c5ffa135d9d7692951e82 437 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 200 207 - T 13-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 THITH_09490 75af32a4a04c5ffa135d9d7692951e82 437 Gene3D G3DSA:3.40.309.10 204 396 2.2E-123 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 THITH_00445 a747c9783cf3f3421a3b29c2b68f67fc 174 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 1 166 17.453 T 13-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 THITH_00445 a747c9783cf3f3421a3b29c2b68f67fc 174 Pfam PF02416 mttA/Hcf106 family 4 48 8.4E-8 T 13-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 THITH_00445 a747c9783cf3f3421a3b29c2b68f67fc 174 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 2 79 1.3E-23 T 13-10-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 THITH_00445 a747c9783cf3f3421a3b29c2b68f67fc 174 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 21 40 2.4E-18 T 13-10-2018 THITH_00445 a747c9783cf3f3421a3b29c2b68f67fc 174 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 40 58 2.4E-18 T 13-10-2018 THITH_00445 a747c9783cf3f3421a3b29c2b68f67fc 174 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 1 21 2.4E-18 T 13-10-2018 THITH_09990 04bd27187631e4a0808567f01b60aebc 303 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 4 300 1.1E-120 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 THITH_09990 04bd27187631e4a0808567f01b60aebc 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 50 69 6.6E-27 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THITH_09990 04bd27187631e4a0808567f01b60aebc 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 253 262 6.6E-27 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THITH_09990 04bd27187631e4a0808567f01b60aebc 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 288 6.6E-27 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THITH_09990 04bd27187631e4a0808567f01b60aebc 303 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 6.6E-27 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THITH_09990 04bd27187631e4a0808567f01b60aebc 303 Gene3D G3DSA:3.40.50.1370 135 295 6.2E-116 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 THITH_09990 04bd27187631e4a0808567f01b60aebc 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 217 227 1.4E-30 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 THITH_09990 04bd27187631e4a0808567f01b60aebc 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 81 94 1.4E-30 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 THITH_09990 04bd27187631e4a0808567f01b60aebc 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 48 62 1.4E-30 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 THITH_09990 04bd27187631e4a0808567f01b60aebc 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 279 290 1.4E-30 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 THITH_09990 04bd27187631e4a0808567f01b60aebc 303 PRINTS PR00102 Ornithine carbamoyltransferase signature 121 135 1.4E-30 T 13-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 THITH_09990 04bd27187631e4a0808567f01b60aebc 303 SUPERFAMILY SSF53671 2 301 5.49E-104 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 THITH_09990 04bd27187631e4a0808567f01b60aebc 303 Gene3D G3DSA:3.40.50.1370 4 134 6.2E-116 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 THITH_09990 04bd27187631e4a0808567f01b60aebc 303 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 152 297 1.8E-48 T 13-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 THITH_09990 04bd27187631e4a0808567f01b60aebc 303 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 3 301 80.095 T 13-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 THITH_09990 04bd27187631e4a0808567f01b60aebc 303 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 4 145 6.1E-52 T 13-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 THITH_09990 04bd27187631e4a0808567f01b60aebc 303 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 50 57 - T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THITH_11140 c8c2acdcbcc07a78985a0f4c18c68aae 981 SUPERFAMILY SSF48695 325 606 4.19E-17 T 13-10-2018 IPR036280 Multiheme cytochrome superfamily THITH_06070 3a522507c2b3659f8c8bce51235010f0 355 Gene3D G3DSA:3.40.1780.10 14 334 2.2E-111 T 13-10-2018 THITH_06070 3a522507c2b3659f8c8bce51235010f0 355 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 337 45.459 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 THITH_06070 3a522507c2b3659f8c8bce51235010f0 355 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 335 9.6E-124 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 THITH_06070 3a522507c2b3659f8c8bce51235010f0 355 SUPERFAMILY SSF111337 1 336 2.35E-129 T 13-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 THITH_06070 3a522507c2b3659f8c8bce51235010f0 355 Pfam PF02547 Queuosine biosynthesis protein 4 336 1.6E-128 T 13-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 THITH_06070 3a522507c2b3659f8c8bce51235010f0 355 Gene3D G3DSA:2.40.10.240 62 159 2.2E-111 T 13-10-2018 THITH_10365 d69266f57c641db0ac9b745dd8812839 154 Gene3D G3DSA:3.40.30.10 72 154 8.3E-28 T 13-10-2018 THITH_10365 d69266f57c641db0ac9b745dd8812839 154 SUPERFAMILY SSF52833 5 153 1.08E-45 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_10365 d69266f57c641db0ac9b745dd8812839 154 TIGRFAM TIGR01958 nuoE_fam: NADH-quinone oxidoreductase, E subunit 10 153 5.0E-50 T 13-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10365 d69266f57c641db0ac9b745dd8812839 154 PIRSF PIRSF000216 1 154 5.1E-52 T 13-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10365 d69266f57c641db0ac9b745dd8812839 154 ProSitePatterns PS01099 Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. 111 129 - T 13-10-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10365 d69266f57c641db0ac9b745dd8812839 154 Gene3D G3DSA:1.10.10.1590 4 71 8.4E-13 T 13-10-2018 THITH_10365 d69266f57c641db0ac9b745dd8812839 154 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 14 153 1.1E-46 T 13-10-2018 THITH_09235 25314f0889f59c2aeaa6c37c878ea5b5 109 Pfam PF09827 CRISPR associated protein Cas2 9 74 6.9E-15 T 13-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 THITH_09235 25314f0889f59c2aeaa6c37c878ea5b5 109 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 9 74 4.3E-10 T 13-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THITH_09235 25314f0889f59c2aeaa6c37c878ea5b5 109 SUPERFAMILY SSF143430 9 82 3.01E-19 T 13-10-2018 THITH_09235 25314f0889f59c2aeaa6c37c878ea5b5 109 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 7 92 12.608 T 13-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THITH_09235 25314f0889f59c2aeaa6c37c878ea5b5 109 Gene3D G3DSA:3.30.70.240 5 90 3.1E-18 T 13-10-2018 THITH_13035 d6d2b0965c846b4ad5c916b38aa9b8f5 159 Gene3D G3DSA:1.10.287.180 1 75 4.3E-32 T 13-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 THITH_13035 d6d2b0965c846b4ad5c916b38aa9b8f5 159 Gene3D G3DSA:3.10.50.30 76 158 6.2E-29 T 13-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 THITH_13035 d6d2b0965c846b4ad5c916b38aa9b8f5 159 Pfam PF03449 Transcription elongation factor, N-terminal 5 74 1.2E-31 T 13-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 THITH_13035 d6d2b0965c846b4ad5c916b38aa9b8f5 159 SUPERFAMILY SSF46557 3 78 4.58E-29 T 13-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 THITH_13035 d6d2b0965c846b4ad5c916b38aa9b8f5 159 SUPERFAMILY SSF54534 82 157 5.62E-23 T 13-10-2018 THITH_13035 d6d2b0965c846b4ad5c916b38aa9b8f5 159 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 121 137 - T 13-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 THITH_13035 d6d2b0965c846b4ad5c916b38aa9b8f5 159 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 5 155 3.1E-56 T 13-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 THITH_13035 d6d2b0965c846b4ad5c916b38aa9b8f5 159 Hamap MF_00105 Transcription elongation factor GreA [greA]. 2 156 32.697 T 13-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 THITH_13035 d6d2b0965c846b4ad5c916b38aa9b8f5 159 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 83 157 8.5E-27 T 13-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 THITH_13035 d6d2b0965c846b4ad5c916b38aa9b8f5 159 PIRSF PIRSF006092 1 159 2.0E-51 T 13-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 THITH_13035 d6d2b0965c846b4ad5c916b38aa9b8f5 159 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 17 48 - T 13-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 THITH_08090 932631a0c1b11d8374168b2160aa4805 208 Pfam PF01814 Hemerythrin HHE cation binding domain 40 178 3.0E-19 T 13-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 THITH_08090 932631a0c1b11d8374168b2160aa4805 208 Gene3D G3DSA:1.20.120.520 26 199 4.2E-45 T 13-10-2018 THITH_01445 6786403a79ba72b531afaae0fde69a12 83 Gene3D G3DSA:2.30.30.400 10 82 8.3E-6 T 13-10-2018 IPR038626 Rof-like superfamily THITH_01445 6786403a79ba72b531afaae0fde69a12 83 SUPERFAMILY SSF101744 2 78 5.23E-10 T 13-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 THITH_15905 9f03cf245016e62ed331110304d7cf81 388 Gene3D G3DSA:3.30.1490.20 108 181 2.0E-20 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 THITH_15905 9f03cf245016e62ed331110304d7cf81 388 Gene3D G3DSA:3.40.50.20 1 107 8.1E-37 T 13-10-2018 THITH_15905 9f03cf245016e62ed331110304d7cf81 388 SUPERFAMILY SSF51246 305 363 3.53E-13 T 13-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 THITH_15905 9f03cf245016e62ed331110304d7cf81 388 SUPERFAMILY SSF56059 103 299 1.01E-60 T 13-10-2018 THITH_15905 9f03cf245016e62ed331110304d7cf81 388 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 8 359 6.8E-115 T 13-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 THITH_15905 9f03cf245016e62ed331110304d7cf81 388 Pfam PF02222 ATP-grasp domain 112 280 1.1E-52 T 13-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type THITH_15905 9f03cf245016e62ed331110304d7cf81 388 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 7 361 40.55 T 13-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 THITH_15905 9f03cf245016e62ed331110304d7cf81 388 SUPERFAMILY SSF52440 8 100 4.89E-24 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily THITH_15905 9f03cf245016e62ed331110304d7cf81 388 Gene3D G3DSA:3.30.470.20 182 377 1.3E-71 T 13-10-2018 THITH_10910 80b3d6f716f8c8d896c16c27a367650a 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.5E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_10910 80b3d6f716f8c8d896c16c27a367650a 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.5E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_10910 80b3d6f716f8c8d896c16c27a367650a 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.5E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_10910 80b3d6f716f8c8d896c16c27a367650a 231 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 1.5E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_10910 80b3d6f716f8c8d896c16c27a367650a 231 SUPERFAMILY SSF51735 1 231 2.5E-74 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_10910 80b3d6f716f8c8d896c16c27a367650a 231 Pfam PF00106 short chain dehydrogenase 2 193 2.2E-30 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_10910 80b3d6f716f8c8d896c16c27a367650a 231 Gene3D G3DSA:3.40.50.720 1 231 2.0E-68 T 13-10-2018 THITH_08570 50a1cdb026f4b4a1dc7d73d7e681bced 296 SUPERFAMILY SSF53850 87 293 5.79E-43 T 13-10-2018 THITH_08570 50a1cdb026f4b4a1dc7d73d7e681bced 296 SUPERFAMILY SSF46785 1 111 3.48E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_08570 50a1cdb026f4b4a1dc7d73d7e681bced 296 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 1.2E-18 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_08570 50a1cdb026f4b4a1dc7d73d7e681bced 296 Gene3D G3DSA:3.40.190.10 91 286 1.7E-59 T 13-10-2018 THITH_08570 50a1cdb026f4b4a1dc7d73d7e681bced 296 Pfam PF03466 LysR substrate binding domain 87 289 1.2E-42 T 13-10-2018 IPR005119 LysR, substrate-binding THITH_08570 50a1cdb026f4b4a1dc7d73d7e681bced 296 Gene3D G3DSA:1.10.10.10 1 88 9.1E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_08570 50a1cdb026f4b4a1dc7d73d7e681bced 296 Gene3D G3DSA:3.40.190.10 162 261 1.7E-59 T 13-10-2018 THITH_02210 6bbd6c58d906c47cd09930dd61ab237f 143 SUPERFAMILY SSF88723 6 136 1.88E-32 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_02210 6bbd6c58d906c47cd09930dd61ab237f 143 Gene3D G3DSA:3.40.50.1010 5 134 2.6E-31 T 13-10-2018 THITH_02210 6bbd6c58d906c47cd09930dd61ab237f 143 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 7 133 10.54 T 13-10-2018 IPR022907 VapC family GO:0004540 THITH_02210 6bbd6c58d906c47cd09930dd61ab237f 143 Pfam PF01850 PIN domain 8 127 1.4E-13 T 13-10-2018 IPR002716 PIN domain THITH_07280 69308939d6a8e1fd8b1030d447fc6fb3 150 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 50 68 - T 13-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site THITH_07280 69308939d6a8e1fd8b1030d447fc6fb3 150 Pfam PF02082 Transcriptional regulator 3 84 3.0E-18 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type THITH_07280 69308939d6a8e1fd8b1030d447fc6fb3 150 TIGRFAM TIGR02944 suf_reg_Xantho: FeS assembly SUF system regulator 1 131 1.2E-37 T 13-10-2018 IPR014290 SUF system FeS cluster assembly regulator THITH_07280 69308939d6a8e1fd8b1030d447fc6fb3 150 SUPERFAMILY SSF46785 3 134 2.73E-28 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_07280 69308939d6a8e1fd8b1030d447fc6fb3 150 Gene3D G3DSA:1.10.10.10 1 137 1.4E-33 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_07280 69308939d6a8e1fd8b1030d447fc6fb3 150 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 3 132 7.2E-27 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type THITH_15980 a7241448f25e5be48214377184a16b92 317 TIGRFAM TIGR01380 glut_syn: glutathione synthase 5 314 4.3E-127 T 13-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 THITH_15980 a7241448f25e5be48214377184a16b92 317 SUPERFAMILY SSF56059 126 313 8.58E-55 T 13-10-2018 THITH_15980 a7241448f25e5be48214377184a16b92 317 Gene3D G3DSA:3.40.50.20 10 117 8.7E-111 T 13-10-2018 THITH_15980 a7241448f25e5be48214377184a16b92 317 Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain 5 123 6.3E-40 T 13-10-2018 IPR004215 Prokaryotic glutathione synthetase, N-terminal GO:0004363|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 THITH_15980 a7241448f25e5be48214377184a16b92 317 Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain 127 299 9.4E-72 T 13-10-2018 IPR004218 Prokaryotic glutathione synthetase, ATP-binding GO:0004363|GO:0005524|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 THITH_15980 a7241448f25e5be48214377184a16b92 317 Hamap MF_00162 Glutathione synthetase [gshB]. 1 317 150.574 T 13-10-2018 IPR006284 Glutathione synthetase, prokaryotic GO:0004363|GO:0005829|GO:0006750 KEGG: 00270+6.3.2.3|KEGG: 00480+6.3.2.3 THITH_15980 a7241448f25e5be48214377184a16b92 317 Gene3D G3DSA:3.30.470.20 118 298 8.7E-111 T 13-10-2018 THITH_15980 a7241448f25e5be48214377184a16b92 317 SUPERFAMILY SSF52440 5 125 2.24E-39 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily THITH_15980 a7241448f25e5be48214377184a16b92 317 Gene3D G3DSA:3.30.1490.20 140 204 8.7E-111 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 THITH_01400 4699fbe16e4a99c66724629eca4e04bd 398 Gene3D G3DSA:3.10.400.10 1 193 6.8E-63 T 13-10-2018 THITH_01400 4699fbe16e4a99c66724629eca4e04bd 398 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 4 389 6.7E-128 T 13-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 THITH_01400 4699fbe16e4a99c66724629eca4e04bd 398 Pfam PF01747 ATP-sulfurylase 178 389 1.3E-76 T 13-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 THITH_01400 4699fbe16e4a99c66724629eca4e04bd 398 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 27 393 46.201 T 13-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 THITH_01400 4699fbe16e4a99c66724629eca4e04bd 398 Gene3D G3DSA:3.40.50.620 194 397 4.8E-82 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_01400 4699fbe16e4a99c66724629eca4e04bd 398 Pfam PF14306 PUA-like domain 2 165 2.4E-36 T 13-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 THITH_01400 4699fbe16e4a99c66724629eca4e04bd 398 SUPERFAMILY SSF52374 175 392 3.1E-81 T 13-10-2018 THITH_01400 4699fbe16e4a99c66724629eca4e04bd 398 SUPERFAMILY SSF88697 1 172 7.66E-43 T 13-10-2018 IPR015947 PUA-like superfamily THITH_06580 ad173a2cba027c5efb5e2f1d412c306e 125 Pfam PF04241 Protein of unknown function (DUF423) 20 106 9.8E-28 T 13-10-2018 IPR006696 Protein of unknown function DUF423 THITH_04125 1b54b9492981b0c685e7152caf9b8c03 484 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 135 154 7.2E-18 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04125 1b54b9492981b0c685e7152caf9b8c03 484 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 164 188 7.2E-18 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04125 1b54b9492981b0c685e7152caf9b8c03 484 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 326 345 7.2E-18 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04125 1b54b9492981b0c685e7152caf9b8c03 484 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 233 257 7.2E-18 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04125 1b54b9492981b0c685e7152caf9b8c03 484 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 378 404 7.2E-18 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04125 1b54b9492981b0c685e7152caf9b8c03 484 Pfam PF00361 Proton-conducting membrane transporter 129 422 1.5E-50 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12975 a73db57b028db4e61f692d6717e07247 417 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 6 417 2.2E-185 T 13-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12975 a73db57b028db4e61f692d6717e07247 417 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 1 417 50.266 T 13-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12975 a73db57b028db4e61f692d6717e07247 417 Gene3D G3DSA:1.10.645.20 4 417 3.4E-175 T 13-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12975 a73db57b028db4e61f692d6717e07247 417 SUPERFAMILY SSF56762 16 417 1.96E-137 T 13-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12975 a73db57b028db4e61f692d6717e07247 417 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 43 54 - T 13-10-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12975 a73db57b028db4e61f692d6717e07247 417 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 417 1.0E-125 T 13-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_02380 48e23948a3eb47976953ebfe0d2eedd4 433 SMART SM00387 327 433 8.3E-24 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_02380 48e23948a3eb47976953ebfe0d2eedd4 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 411 7.7E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_02380 48e23948a3eb47976953ebfe0d2eedd4 433 PRINTS PR00344 Bacterial sensor protein C-terminal signature 362 376 7.7E-8 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_02380 48e23948a3eb47976953ebfe0d2eedd4 433 SUPERFAMILY SSF47384 223 276 7.26E-6 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_02380 48e23948a3eb47976953ebfe0d2eedd4 433 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 328 431 2.8E-15 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_02380 48e23948a3eb47976953ebfe0d2eedd4 433 Gene3D G3DSA:3.30.565.10 288 433 3.3E-30 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_02380 48e23948a3eb47976953ebfe0d2eedd4 433 Gene3D G3DSA:1.10.287.130 178 282 2.1E-9 T 13-10-2018 THITH_02380 48e23948a3eb47976953ebfe0d2eedd4 433 SUPERFAMILY SSF55874 293 431 1.83E-28 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_10525 402d4222d042edf53ada4a7a41afde9e 235 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_10525 402d4222d042edf53ada4a7a41afde9e 235 SUPERFAMILY SSF52540 8 234 4.8E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_10525 402d4222d042edf53ada4a7a41afde9e 235 Pfam PF00005 ABC transporter 28 180 1.6E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_10525 402d4222d042edf53ada4a7a41afde9e 235 Gene3D G3DSA:3.40.50.300 6 235 4.6E-64 T 13-10-2018 THITH_10525 402d4222d042edf53ada4a7a41afde9e 235 SMART SM00382 37 234 1.4E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_10390 9dc9268ad2e3c32e85870882cfd63f91 826 PIRSF PIRSF000460 8 826 1.7E-227 T 13-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THITH_10390 9dc9268ad2e3c32e85870882cfd63f91 826 Gene3D G3DSA:3.40.50.2000 478 804 0.0 T 13-10-2018 THITH_10390 9dc9268ad2e3c32e85870882cfd63f91 826 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 664 676 - T 13-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THITH_10390 9dc9268ad2e3c32e85870882cfd63f91 826 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 20 818 0.0 T 13-10-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THITH_10390 9dc9268ad2e3c32e85870882cfd63f91 826 SUPERFAMILY SSF53756 15 824 0.0 T 13-10-2018 THITH_10390 9dc9268ad2e3c32e85870882cfd63f91 826 Gene3D G3DSA:3.40.50.2000 35 821 0.0 T 13-10-2018 THITH_10390 9dc9268ad2e3c32e85870882cfd63f91 826 Pfam PF00343 Carbohydrate phosphorylase 108 818 0.0 T 13-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THITH_14095 f9eee91f7900b6249417acf40e1eb603 571 Gene3D G3DSA:3.90.1580.10 117 346 1.1E-22 T 13-10-2018 THITH_14095 f9eee91f7900b6249417acf40e1eb603 571 SUPERFAMILY SSF56436 121 347 5.42E-26 T 13-10-2018 IPR016187 C-type lectin fold THITH_14095 f9eee91f7900b6249417acf40e1eb603 571 Pfam PF03781 Sulfatase-modifying factor enzyme 1 119 320 2.3E-18 T 13-10-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 THITH_03435 1677eee7aa3ab53ecd6f4d216e28d944 1550 Pfam PF13489 Methyltransferase domain 24 167 5.5E-12 T 13-10-2018 THITH_03435 1677eee7aa3ab53ecd6f4d216e28d944 1550 Gene3D G3DSA:3.30.870.10 335 447 6.1E-15 T 13-10-2018 THITH_03435 1677eee7aa3ab53ecd6f4d216e28d944 1550 Pfam PF13091 PLD-like domain 336 438 3.6E-11 T 13-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THITH_03435 1677eee7aa3ab53ecd6f4d216e28d944 1550 Gene3D G3DSA:3.40.50.300 464 642 3.1E-42 T 13-10-2018 THITH_03435 1677eee7aa3ab53ecd6f4d216e28d944 1550 SMART SM00490 720 800 2.7E-9 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_03435 1677eee7aa3ab53ecd6f4d216e28d944 1550 SUPERFAMILY SSF51306 1186 1314 2.09E-11 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily THITH_03435 1677eee7aa3ab53ecd6f4d216e28d944 1550 Gene3D G3DSA:3.40.50.300 644 822 6.2E-34 T 13-10-2018 THITH_03435 1677eee7aa3ab53ecd6f4d216e28d944 1550 Pfam PF00271 Helicase conserved C-terminal domain 702 798 2.6E-9 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_03435 1677eee7aa3ab53ecd6f4d216e28d944 1550 Gene3D G3DSA:2.10.109.10 1204 1320 2.7E-9 T 13-10-2018 THITH_03435 1677eee7aa3ab53ecd6f4d216e28d944 1550 Pfam PF04851 Type III restriction enzyme, res subunit 478 625 7.3E-28 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THITH_03435 1677eee7aa3ab53ecd6f4d216e28d944 1550 SMART SM00487 474 660 2.8E-19 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_03435 1677eee7aa3ab53ecd6f4d216e28d944 1550 SUPERFAMILY SSF52540 524 817 1.14E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_03435 1677eee7aa3ab53ecd6f4d216e28d944 1550 SUPERFAMILY SSF53335 6 166 1.05E-25 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_03435 1677eee7aa3ab53ecd6f4d216e28d944 1550 Gene3D G3DSA:3.40.50.150 1 199 1.4E-55 T 13-10-2018 THITH_13720 b60a2dadc87b27fefe2abecfa8488c1d 321 SUPERFAMILY SSF53328 11 214 2.09E-36 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THITH_13720 b60a2dadc87b27fefe2abecfa8488c1d 321 Pfam PF00551 Formyl transferase 80 184 2.0E-21 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THITH_13720 b60a2dadc87b27fefe2abecfa8488c1d 321 Gene3D G3DSA:3.40.50.12230 10 312 1.2E-46 T 13-10-2018 THITH_06900 731cab9ea409037dfedfa425b39dce4e 56 Pfam PF04995 Heme exporter protein D (CcmD) 8 48 3.3E-9 T 13-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 THITH_06900 731cab9ea409037dfedfa425b39dce4e 56 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 5 44 3.1E-10 T 13-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 THITH_16175 731cab9ea409037dfedfa425b39dce4e 56 Pfam PF04995 Heme exporter protein D (CcmD) 8 48 3.3E-9 T 13-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 THITH_16175 731cab9ea409037dfedfa425b39dce4e 56 TIGRFAM TIGR03141 cytochro_ccmD: heme exporter protein CcmD 5 44 3.1E-10 T 13-10-2018 IPR007078 Haem exporter protein D (CcmD) GO:0015886|GO:0016021|GO:0017004 THITH_12530 af7b659c0e90d0a1c3e8a2af558ec435 211 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 170 4.5E-12 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THITH_12530 af7b659c0e90d0a1c3e8a2af558ec435 211 PIRSF PIRSF009320 1 210 5.4E-37 T 13-10-2018 THITH_12530 af7b659c0e90d0a1c3e8a2af558ec435 211 Gene3D G3DSA:3.40.50.300 3 210 1.9E-44 T 13-10-2018 THITH_12530 af7b659c0e90d0a1c3e8a2af558ec435 211 SUPERFAMILY SSF52540 1 207 3.58E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_05015 776918939eff149d412a4aa928325d4b 895 SMART SM00881 9 104 5.3E-32 T 13-10-2018 IPR003781 CoA-binding GO:0048037 THITH_05015 776918939eff149d412a4aa928325d4b 895 SUPERFAMILY SSF56059 495 707 1.11E-36 T 13-10-2018 THITH_05015 776918939eff149d412a4aa928325d4b 895 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 155 292 6.3E-55 T 13-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain THITH_05015 776918939eff149d412a4aa928325d4b 895 Gene3D G3DSA:3.40.50.720 4 133 3.8E-41 T 13-10-2018 THITH_05015 776918939eff149d412a4aa928325d4b 895 SUPERFAMILY SSF51735 3 142 2.28E-35 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_05015 776918939eff149d412a4aa928325d4b 895 SUPERFAMILY SSF52210 133 296 9.16E-45 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THITH_05015 776918939eff149d412a4aa928325d4b 895 Gene3D G3DSA:3.40.50.261 134 294 1.2E-58 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THITH_05015 776918939eff149d412a4aa928325d4b 895 SUPERFAMILY SSF52210 299 457 1.3E-42 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THITH_05015 776918939eff149d412a4aa928325d4b 895 Gene3D G3DSA:3.30.470.20 493 703 3.2E-76 T 13-10-2018 THITH_05015 776918939eff149d412a4aa928325d4b 895 SUPERFAMILY SSF55729 738 883 1.27E-22 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_05015 776918939eff149d412a4aa928325d4b 895 Pfam PF13380 CoA binding domain 13 138 2.8E-24 T 13-10-2018 IPR003781 CoA-binding GO:0048037 THITH_05015 776918939eff149d412a4aa928325d4b 895 Gene3D G3DSA:3.40.50.261 297 463 5.1E-55 T 13-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 THITH_05015 776918939eff149d412a4aa928325d4b 895 Gene3D G3DSA:3.40.630.30 732 895 5.7E-45 T 13-10-2018 THITH_05015 776918939eff149d412a4aa928325d4b 895 Pfam PF13549 ATP-grasp domain 484 705 4.0E-82 T 13-10-2018 THITH_05015 776918939eff149d412a4aa928325d4b 895 Gene3D G3DSA:3.30.1490.20 510 587 3.2E-76 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 THITH_05015 776918939eff149d412a4aa928325d4b 895 Pfam PF00583 Acetyltransferase (GNAT) family 787 877 1.0E-10 T 13-10-2018 IPR000182 GNAT domain THITH_13770 3509aae7cb9039fc0f86ce2a69a42c5e 346 Pfam PF09615 CRISPR-associated protein (Cas_Csy3) 9 342 8.4E-149 T 13-10-2018 IPR013399 CRISPR-associated protein Csy3 THITH_13770 3509aae7cb9039fc0f86ce2a69a42c5e 346 TIGRFAM TIGR02566 cas_Csy3: CRISPR type I-F/YPEST-associated protein Csy3 9 344 1.1E-131 T 13-10-2018 IPR013399 CRISPR-associated protein Csy3 THITH_01480 6361dc55e931dd31f0a0430366893fbb 298 Gene3D G3DSA:2.60.260.20 125 194 2.1E-16 T 13-10-2018 THITH_01480 6361dc55e931dd31f0a0430366893fbb 298 SUPERFAMILY SSF49493 123 209 4.58E-18 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THITH_01480 6361dc55e931dd31f0a0430366893fbb 298 Gene3D G3DSA:1.10.287.110 2 121 7.1E-34 T 13-10-2018 IPR036869 Chaperone J-domain superfamily THITH_01480 6361dc55e931dd31f0a0430366893fbb 298 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 13-10-2018 IPR018253 DnaJ domain, conserved site THITH_01480 6361dc55e931dd31f0a0430366893fbb 298 SUPERFAMILY SSF46565 1 118 1.57E-32 T 13-10-2018 IPR036869 Chaperone J-domain superfamily THITH_01480 6361dc55e931dd31f0a0430366893fbb 298 SMART SM00271 4 61 3.6E-29 T 13-10-2018 IPR001623 DnaJ domain THITH_01480 6361dc55e931dd31f0a0430366893fbb 298 Pfam PF00226 DnaJ domain 5 66 5.3E-25 T 13-10-2018 IPR001623 DnaJ domain THITH_01480 6361dc55e931dd31f0a0430366893fbb 298 PRINTS PR00625 DnaJ domain signature 25 40 7.1E-23 T 13-10-2018 IPR001623 DnaJ domain THITH_01480 6361dc55e931dd31f0a0430366893fbb 298 PRINTS PR00625 DnaJ domain signature 41 61 7.1E-23 T 13-10-2018 IPR001623 DnaJ domain THITH_01480 6361dc55e931dd31f0a0430366893fbb 298 PRINTS PR00625 DnaJ domain signature 7 25 7.1E-23 T 13-10-2018 IPR001623 DnaJ domain THITH_01480 6361dc55e931dd31f0a0430366893fbb 298 PRINTS PR00625 DnaJ domain signature 61 80 7.1E-23 T 13-10-2018 IPR001623 DnaJ domain THITH_01480 6361dc55e931dd31f0a0430366893fbb 298 Pfam PF01556 DnaJ C terminal domain 135 272 2.5E-30 T 13-10-2018 IPR002939 Chaperone DnaJ, C-terminal THITH_01480 6361dc55e931dd31f0a0430366893fbb 298 SUPERFAMILY SSF49493 201 274 2.09E-18 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THITH_01480 6361dc55e931dd31f0a0430366893fbb 298 Gene3D G3DSA:2.60.260.20 195 272 3.9E-27 T 13-10-2018 THITH_03065 1877fc540b2b04a59f71c257f86a0dae 58 SUPERFAMILY SSF46785 8 53 3.81E-7 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_03065 1877fc540b2b04a59f71c257f86a0dae 58 Gene3D G3DSA:1.10.10.10 3 54 1.3E-13 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_11540 5a1ae34cf968242c93f9bd5b4cf2f074 286 Pfam PF05114 Protein of unknown function (DUF692) 9 273 7.8E-97 T 13-10-2018 IPR007801 Uncharacterised protein family UPF0276 THITH_11540 5a1ae34cf968242c93f9bd5b4cf2f074 286 Gene3D G3DSA:3.20.20.150 6 283 5.6E-83 T 13-10-2018 THITH_11540 5a1ae34cf968242c93f9bd5b4cf2f074 286 SUPERFAMILY SSF51658 32 273 5.18E-14 T 13-10-2018 IPR036237 Xylose isomerase-like superfamily THITH_14340 e7afada286a56ff8f072d6b3575bcf80 231 SUPERFAMILY SSF56808 6 226 1.01E-79 T 13-10-2018 IPR023674 Ribosomal protein L1-like THITH_14340 e7afada286a56ff8f072d6b3575bcf80 231 PIRSF PIRSF002155 1 227 5.5E-75 T 13-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14340 e7afada286a56ff8f072d6b3575bcf80 231 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 13-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14340 e7afada286a56ff8f072d6b3575bcf80 231 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 2.6E-102 T 13-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 THITH_14340 e7afada286a56ff8f072d6b3575bcf80 231 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 42.782 T 13-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 THITH_14340 e7afada286a56ff8f072d6b3575bcf80 231 Gene3D G3DSA:3.40.50.790 68 159 5.5E-78 T 13-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich THITH_14340 e7afada286a56ff8f072d6b3575bcf80 231 Pfam PF00687 Ribosomal protein L1p/L10e family 34 220 1.5E-50 T 13-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein THITH_14340 e7afada286a56ff8f072d6b3575bcf80 231 Gene3D G3DSA:3.30.190.20 21 225 5.5E-78 T 13-10-2018 THITH_07685 97e3c22fe82b6c1d8603f89fad827f94 318 SUPERFAMILY SSF53901 2 318 1.32E-71 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 THITH_07685 97e3c22fe82b6c1d8603f89fad827f94 318 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 2 318 71.673 T 13-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 THITH_07685 97e3c22fe82b6c1d8603f89fad827f94 318 Gene3D G3DSA:3.40.47.10 1 318 6.7E-134 T 13-10-2018 IPR016039 Thiolase-like GO:0003824 THITH_07685 97e3c22fe82b6c1d8603f89fad827f94 318 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 4 318 6.2E-136 T 13-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 THITH_07685 97e3c22fe82b6c1d8603f89fad827f94 318 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 184 2.6E-33 T 13-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 THITH_07685 97e3c22fe82b6c1d8603f89fad827f94 318 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 229 318 1.0E-37 T 13-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 THITH_14025 dea9b8a95fa820e3a6e504598bd6974d 196 Pfam PF02545 Maf-like protein 5 185 1.4E-56 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 THITH_14025 dea9b8a95fa820e3a6e504598bd6974d 196 SUPERFAMILY SSF52972 2 185 1.9E-63 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like THITH_14025 dea9b8a95fa820e3a6e504598bd6974d 196 TIGRFAM TIGR00172 maf: septum formation protein Maf 1 183 2.7E-53 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 THITH_14025 dea9b8a95fa820e3a6e504598bd6974d 196 Gene3D G3DSA:3.90.950.10 4 188 2.1E-68 T 13-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like THITH_14025 dea9b8a95fa820e3a6e504598bd6974d 196 Hamap MF_00528 Septum formation protein Maf [maf]. 4 190 32.499 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 THITH_14025 dea9b8a95fa820e3a6e504598bd6974d 196 PIRSF PIRSF006305 1 192 1.9E-55 T 13-10-2018 IPR003697 Maf-like protein GO:0047429 THITH_15890 feac0eb715c1ded5847c07f11fc55732 105 Gene3D G3DSA:1.10.760.10 22 104 7.9E-23 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_15890 feac0eb715c1ded5847c07f11fc55732 105 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 23 100 3.1E-12 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_15890 feac0eb715c1ded5847c07f11fc55732 105 SUPERFAMILY SSF46626 5 102 5.08E-22 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_16830 7d8104118298876e1b916e751dfa192e 412 Gene3D G3DSA:2.130.10.10 130 307 2.7E-12 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 THITH_16830 7d8104118298876e1b916e751dfa192e 412 Gene3D G3DSA:2.130.10.10 308 401 3.2E-16 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 THITH_16830 7d8104118298876e1b916e751dfa192e 412 Gene3D G3DSA:2.130.10.10 7 129 3.5E-12 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 THITH_16830 7d8104118298876e1b916e751dfa192e 412 SUPERFAMILY SSF82171 48 396 3.49E-30 T 13-10-2018 THITH_02765 bcb2f66438024c0ab347762f22e466b9 480 PIRSF PIRSF004919 16 478 1.0E-138 T 13-10-2018 IPR025502 TldD THITH_02765 bcb2f66438024c0ab347762f22e466b9 480 Pfam PF01523 Putative modulator of DNA gyrase 37 329 1.3E-67 T 13-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 THITH_02765 bcb2f66438024c0ab347762f22e466b9 480 Gene3D G3DSA:3.30.2290.10 15 237 1.8E-16 T 13-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal THITH_02765 bcb2f66438024c0ab347762f22e466b9 480 SUPERFAMILY SSF111283 19 477 1.44E-131 T 13-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 THITH_07680 c6a2c8a9677ba37c5e097d9f8e04188f 342 Gene3D G3DSA:3.40.718.10 4 341 1.1E-126 T 13-10-2018 THITH_07680 c6a2c8a9677ba37c5e097d9f8e04188f 342 SUPERFAMILY SSF53659 5 336 2.75E-101 T 13-10-2018 THITH_07680 c6a2c8a9677ba37c5e097d9f8e04188f 342 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 341 143.574 T 13-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 THITH_07680 c6a2c8a9677ba37c5e097d9f8e04188f 342 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 7 336 2.0E-105 T 13-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 THITH_07680 c6a2c8a9677ba37c5e097d9f8e04188f 342 PIRSF PIRSF002465 3 339 6.5E-126 T 13-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 THITH_07680 c6a2c8a9677ba37c5e097d9f8e04188f 342 Pfam PF02504 Fatty acid synthesis protein 6 327 1.3E-103 T 13-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 THITH_14565 ded37cf04744dde05b1ba16b6497e93f 252 SUPERFAMILY SSF102705 7 251 3.27E-77 T 13-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily THITH_14565 ded37cf04744dde05b1ba16b6497e93f 252 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 11 239 1.8E-57 T 13-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 THITH_14565 ded37cf04744dde05b1ba16b6497e93f 252 Gene3D G3DSA:3.40.1390.30 101 223 3.3E-79 T 13-10-2018 THITH_14565 ded37cf04744dde05b1ba16b6497e93f 252 Gene3D G3DSA:3.40.1390.30 11 240 3.3E-79 T 13-10-2018 THITH_14565 ded37cf04744dde05b1ba16b6497e93f 252 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 8 250 2.1E-60 T 13-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 THITH_02940 0bc0736d19824aef6d74ca5aa9ecc75e 235 PIRSF PIRSF000370 24 235 2.6E-66 T 13-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 THITH_02940 0bc0736d19824aef6d74ca5aa9ecc75e 235 TIGRFAM TIGR04349 rSAM_QueE_gams: putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 26 235 1.8E-102 T 13-10-2018 IPR027621 Putative 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE THITH_02940 0bc0736d19824aef6d74ca5aa9ecc75e 235 Gene3D G3DSA:3.20.20.70 26 229 3.5E-35 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_02940 0bc0736d19824aef6d74ca5aa9ecc75e 235 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 26 232 37.152 T 13-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 THITH_02940 0bc0736d19824aef6d74ca5aa9ecc75e 235 Pfam PF13394 4Fe-4S single cluster domain 47 128 2.3E-9 T 13-10-2018 THITH_02940 0bc0736d19824aef6d74ca5aa9ecc75e 235 SUPERFAMILY SSF102114 49 159 3.92E-16 T 13-10-2018 THITH_02940 0bc0736d19824aef6d74ca5aa9ecc75e 235 Pfam PF04055 Radical SAM superfamily 49 146 4.2E-15 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THITH_06585 09e26266695fa8ac26a317e60b3ff1e3 160 SUPERFAMILY SSF89963 2 85 3.92E-29 T 13-10-2018 IPR036183 YajQ-like superfamily THITH_06585 09e26266695fa8ac26a317e60b3ff1e3 160 SUPERFAMILY SSF89963 89 160 2.62E-28 T 13-10-2018 IPR036183 YajQ-like superfamily THITH_06585 09e26266695fa8ac26a317e60b3ff1e3 160 Gene3D G3DSA:3.30.70.990 9 97 1.8E-59 T 13-10-2018 IPR035570 UPF0234, N-terminal THITH_06585 09e26266695fa8ac26a317e60b3ff1e3 160 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 1 160 28.979 T 13-10-2018 IPR007551 Protein of unknown function DUF520 THITH_06585 09e26266695fa8ac26a317e60b3ff1e3 160 Pfam PF04461 Protein of unknown function (DUF520) 2 159 1.8E-64 T 13-10-2018 IPR007551 Protein of unknown function DUF520 THITH_06585 09e26266695fa8ac26a317e60b3ff1e3 160 Gene3D G3DSA:3.30.70.860 3 159 1.8E-59 T 13-10-2018 IPR035571 UPF0234-like, C-terminal THITH_03635 8a5bc3a8158a05440ab4138c8c5becd5 338 SUPERFAMILY SSF51735 1 182 3.95E-75 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_03635 8a5bc3a8158a05440ab4138c8c5becd5 338 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 326 2.9E-63 T 13-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THITH_03635 8a5bc3a8158a05440ab4138c8c5becd5 338 PIRSF PIRSF000116 4 205 1.5E-44 T 13-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THITH_03635 8a5bc3a8158a05440ab4138c8c5becd5 338 PIRSF PIRSF000116 201 332 1.2E-14 T 13-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THITH_03635 8a5bc3a8158a05440ab4138c8c5becd5 338 Gene3D G3DSA:3.40.50.720 1 181 2.2E-78 T 13-10-2018 THITH_03635 8a5bc3a8158a05440ab4138c8c5becd5 338 SUPERFAMILY SSF48179 183 332 6.8E-69 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THITH_03635 8a5bc3a8158a05440ab4138c8c5becd5 338 Gene3D G3DSA:1.10.3730.40 182 338 2.2E-74 T 13-10-2018 THITH_03635 8a5bc3a8158a05440ab4138c8c5becd5 338 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 14 177 3.6E-74 T 13-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THITH_03635 8a5bc3a8158a05440ab4138c8c5becd5 338 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 14 326 3.2E-129 T 13-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THITH_03635 8a5bc3a8158a05440ab4138c8c5becd5 338 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 1 328 45.068 T 13-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 THITH_16585 36f5024ae197d76136b24068dfe7f813 158 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 135 12.352 T 13-10-2018 IPR022907 VapC family GO:0004540 THITH_16585 36f5024ae197d76136b24068dfe7f813 158 Pfam PF01850 PIN domain 2 127 1.7E-16 T 13-10-2018 IPR002716 PIN domain THITH_16585 36f5024ae197d76136b24068dfe7f813 158 Gene3D G3DSA:3.40.50.1010 1 137 1.9E-35 T 13-10-2018 THITH_16585 36f5024ae197d76136b24068dfe7f813 158 SUPERFAMILY SSF88723 1 136 2.16E-28 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_01515 5c0e420366a202e22303e5db2fe25d3b 354 Gene3D G3DSA:1.10.1670.10 8 209 2.9E-85 T 13-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 THITH_01515 5c0e420366a202e22303e5db2fe25d3b 354 SMART SM00478 38 189 8.3E-46 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THITH_01515 5c0e420366a202e22303e5db2fe25d3b 354 SMART SM00525 190 210 0.0047 T 13-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 THITH_01515 5c0e420366a202e22303e5db2fe25d3b 354 Pfam PF00633 Helix-hairpin-helix motif 100 126 1.8E-5 T 13-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 THITH_01515 5c0e420366a202e22303e5db2fe25d3b 354 ProSitePatterns PS01155 Endonuclease III family signature. 101 130 - T 13-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 THITH_01515 5c0e420366a202e22303e5db2fe25d3b 354 Gene3D G3DSA:1.10.340.30 20 131 2.9E-85 T 13-10-2018 THITH_01515 5c0e420366a202e22303e5db2fe25d3b 354 SUPERFAMILY SSF55811 219 343 2.57E-16 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 THITH_01515 5c0e420366a202e22303e5db2fe25d3b 354 Pfam PF14815 NUDIX domain 235 343 6.2E-19 T 13-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 THITH_01515 5c0e420366a202e22303e5db2fe25d3b 354 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 5 271 2.0E-106 T 13-10-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 THITH_01515 5c0e420366a202e22303e5db2fe25d3b 354 Gene3D G3DSA:3.90.79.10 229 346 3.9E-8 T 13-10-2018 THITH_01515 5c0e420366a202e22303e5db2fe25d3b 354 SUPERFAMILY SSF48150 3 222 2.67E-75 T 13-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 THITH_01515 5c0e420366a202e22303e5db2fe25d3b 354 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 34 166 1.7E-19 T 13-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 THITH_01515 5c0e420366a202e22303e5db2fe25d3b 354 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 191 207 - T 13-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 THITH_14440 6ad2b009c1176aaad70431cd2cc861ce 410 SMART SM00842 10 196 8.6E-106 T 13-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 THITH_14440 6ad2b009c1176aaad70431cd2cc861ce 410 Gene3D G3DSA:3.30.420.40 13 371 5.2E-125 T 13-10-2018 THITH_14440 6ad2b009c1176aaad70431cd2cc861ce 410 Pfam PF14450 Cell division protein FtsA 11 192 6.0E-12 T 13-10-2018 THITH_14440 6ad2b009c1176aaad70431cd2cc861ce 410 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 9 378 2.1E-155 T 13-10-2018 IPR020823 Cell division protein FtsA THITH_14440 6ad2b009c1176aaad70431cd2cc861ce 410 Pfam PF02491 SHS2 domain inserted in FTSA 85 162 3.8E-34 T 13-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 THITH_14440 6ad2b009c1176aaad70431cd2cc861ce 410 Gene3D G3DSA:3.90.640.10 235 300 5.2E-125 T 13-10-2018 THITH_14440 6ad2b009c1176aaad70431cd2cc861ce 410 Gene3D G3DSA:3.30.1490.110 87 169 5.2E-125 T 13-10-2018 THITH_14440 6ad2b009c1176aaad70431cd2cc861ce 410 Pfam PF14450 Cell division protein FtsA 207 374 3.9E-24 T 13-10-2018 THITH_14440 6ad2b009c1176aaad70431cd2cc861ce 410 PIRSF PIRSF003101 1 410 6.8E-160 T 13-10-2018 IPR020823 Cell division protein FtsA THITH_14440 6ad2b009c1176aaad70431cd2cc861ce 410 SUPERFAMILY SSF53067 198 378 2.45E-50 T 13-10-2018 THITH_14440 6ad2b009c1176aaad70431cd2cc861ce 410 SUPERFAMILY SSF53067 9 197 7.78E-63 T 13-10-2018 THITH_14440 6ad2b009c1176aaad70431cd2cc861ce 410 Hamap MF_02033 Cell division protein FtsA [ftsA]. 6 410 32.251 T 13-10-2018 IPR020823 Cell division protein FtsA THITH_14440 6ad2b009c1176aaad70431cd2cc861ce 410 Gene3D G3DSA:3.30.420.40 197 352 5.2E-125 T 13-10-2018 THITH_12830 cb4016cf8e0ac0b5b3499a36ed29a16c 437 SUPERFAMILY SSF52172 1 179 1.57E-38 T 13-10-2018 IPR011006 CheY-like superfamily THITH_12830 cb4016cf8e0ac0b5b3499a36ed29a16c 437 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 348 357 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site THITH_12830 cb4016cf8e0ac0b5b3499a36ed29a16c 437 Pfam PF00158 Sigma-54 interaction domain 135 301 3.0E-68 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THITH_12830 cb4016cf8e0ac0b5b3499a36ed29a16c 437 SMART SM00448 2 109 7.7E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_12830 cb4016cf8e0ac0b5b3499a36ed29a16c 437 SUPERFAMILY SSF52540 135 376 2.81E-74 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_12830 cb4016cf8e0ac0b5b3499a36ed29a16c 437 Pfam PF00072 Response regulator receiver domain 4 108 1.3E-21 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_12830 cb4016cf8e0ac0b5b3499a36ed29a16c 437 Gene3D G3DSA:3.40.50.2300 1 125 2.2E-30 T 13-10-2018 THITH_12830 cb4016cf8e0ac0b5b3499a36ed29a16c 437 Gene3D G3DSA:3.40.50.300 128 306 3.1E-64 T 13-10-2018 THITH_12830 cb4016cf8e0ac0b5b3499a36ed29a16c 437 Gene3D G3DSA:1.10.8.60 307 382 5.7E-21 T 13-10-2018 THITH_12830 cb4016cf8e0ac0b5b3499a36ed29a16c 437 SMART SM00382 155 299 5.3E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_07345 31029538aefed390759c1bb9891b150a 286 Gene3D G3DSA:1.20.120.350 113 240 1.5E-10 T 13-10-2018 IPR027359 Voltage-dependent channel domain superfamily THITH_07345 31029538aefed390759c1bb9891b150a 286 SUPERFAMILY SSF81324 118 227 1.73E-6 T 13-10-2018 THITH_17370 f6073d837d6b7d5e89571e5064ba3f50 194 Pfam PF01864 CDP-archaeol synthase 38 190 3.7E-5 T 13-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 THITH_10410 429edb1db73de5b693b58ec8832714ac 307 Gene3D G3DSA:2.160.10.10 79 287 1.7E-65 T 13-10-2018 THITH_10410 429edb1db73de5b693b58ec8832714ac 307 Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD 1 66 1.2E-7 T 13-10-2018 IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region GO:0009245|GO:0016747 THITH_10410 429edb1db73de5b693b58ec8832714ac 307 TIGRFAM TIGR01853 lipid_A_lpxD: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 2 305 5.0E-94 T 13-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 THITH_10410 429edb1db73de5b693b58ec8832714ac 307 Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. 1 304 31.049 T 13-10-2018 IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD GO:0009245|GO:0016410 THITH_10410 429edb1db73de5b693b58ec8832714ac 307 SUPERFAMILY SSF51161 43 291 2.22E-70 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily THITH_10410 429edb1db73de5b693b58ec8832714ac 307 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 236 270 7.1E-5 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_10410 429edb1db73de5b693b58ec8832714ac 307 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 78 109 6.6E-5 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_10410 429edb1db73de5b693b58ec8832714ac 307 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 200 235 6.3E-8 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_10410 429edb1db73de5b693b58ec8832714ac 307 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 132 157 3.9E-5 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_10400 82f1206673c78e77dd770aef63b546bf 259 Gene3D G3DSA:1.20.1180.10 192 258 3.1E-14 T 13-10-2018 IPR037157 UDP-N-acetylglucosamine O-acyltransferase, C-terminal domain superfamily KEGG: 00540+2.3.1.129 THITH_10400 82f1206673c78e77dd770aef63b546bf 259 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 2 30 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 THITH_10400 82f1206673c78e77dd770aef63b546bf 259 TIGRFAM TIGR01852 lipid_A_lpxA: acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase 2 253 5.9E-96 T 13-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 THITH_10400 82f1206673c78e77dd770aef63b546bf 259 Hamap MF_00387 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase [lpxA]. 1 255 40.596 T 13-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 THITH_10400 82f1206673c78e77dd770aef63b546bf 259 PIRSF PIRSF000456 1 259 1.5E-97 T 13-10-2018 IPR010137 Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase GO:0008610|GO:0008780 KEGG: 00540+2.3.1.129 THITH_10400 82f1206673c78e77dd770aef63b546bf 259 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 29 63 1.7E-6 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_10400 82f1206673c78e77dd770aef63b546bf 259 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 103 131 7.9E-8 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_10400 82f1206673c78e77dd770aef63b546bf 259 Gene3D G3DSA:2.160.10.10 1 191 5.5E-49 T 13-10-2018 THITH_10400 82f1206673c78e77dd770aef63b546bf 259 SUPERFAMILY SSF51161 1 254 3.14E-69 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily THITH_10400 82f1206673c78e77dd770aef63b546bf 259 Pfam PF13720 Udp N-acetylglucosamine O-acyltransferase; Domain 2 174 253 3.6E-21 T 13-10-2018 IPR029098 UDP N-acetylglucosamine O-acyltransferase, C-terminal KEGG: 00540+2.3.1.129 THITH_03860 db3933420a7baf80be972d207a872922 219 Pfam PF00753 Metallo-beta-lactamase superfamily 12 193 1.3E-30 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_03860 db3933420a7baf80be972d207a872922 219 SUPERFAMILY SSF56281 7 209 1.49E-54 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_03860 db3933420a7baf80be972d207a872922 219 Gene3D G3DSA:3.60.15.10 4 211 1.3E-73 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_03860 db3933420a7baf80be972d207a872922 219 SMART SM00849 13 193 2.3E-34 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_15355 eb71489ce851ff04dca8b092cab46c5e 218 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 60 201 5.0E-27 T 13-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 THITH_15355 eb71489ce851ff04dca8b092cab46c5e 218 Gene3D G3DSA:3.40.80.10 36 217 1.2E-57 T 13-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 THITH_15355 eb71489ce851ff04dca8b092cab46c5e 218 SMART SM00644 49 200 2.8E-53 T 13-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 THITH_15355 eb71489ce851ff04dca8b092cab46c5e 218 SUPERFAMILY SSF55846 39 215 8.9E-66 T 13-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 THITH_05225 fa35e87b919ac9c9f342477c12a64a0b 317 Pfam PF12760 Transposase zinc-ribbon domain 23 69 1.7E-14 T 13-10-2018 IPR024442 Transposase, zinc-ribbon THITH_05225 fa35e87b919ac9c9f342477c12a64a0b 317 Pfam PF12762 ISXO2-like transposase domain 138 283 1.8E-29 T 13-10-2018 IPR024445 ISXO2-like transposase domain THITH_05225 fa35e87b919ac9c9f342477c12a64a0b 317 SMART SM01126 137 283 1.8E-36 T 13-10-2018 IPR024445 ISXO2-like transposase domain THITH_10565 3296182be376233807f54395cfda2a04 321 SUPERFAMILY SSF53335 41 225 2.41E-21 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_10565 3296182be376233807f54395cfda2a04 321 Pfam PF13649 Methyltransferase domain 74 179 5.2E-13 T 13-10-2018 THITH_10565 3296182be376233807f54395cfda2a04 321 Gene3D G3DSA:3.40.50.150 18 212 1.2E-20 T 13-10-2018 THITH_07520 1c7d3d762c55ed83442c28ec23ef81f0 106 Pfam PF03927 NapD protein 1 77 5.1E-24 T 13-10-2018 IPR005623 Chaperone NapD, nitrate reductase assembly THITH_07520 1c7d3d762c55ed83442c28ec23ef81f0 106 Gene3D G3DSA:3.30.70.920 1 71 9.6E-17 T 13-10-2018 THITH_07520 1c7d3d762c55ed83442c28ec23ef81f0 106 Hamap MF_02200 Chaperone NapD [napD]. 1 78 18.32 T 13-10-2018 IPR005623 Chaperone NapD, nitrate reductase assembly THITH_12260 d1c920bf5f226ba831c8398b40e94799 187 Pfam PF14559 Tetratricopeptide repeat 92 140 3.1E-6 T 13-10-2018 THITH_12260 d1c920bf5f226ba831c8398b40e94799 187 Gene3D G3DSA:1.25.40.10 83 186 7.6E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_12260 d1c920bf5f226ba831c8398b40e94799 187 SUPERFAMILY SSF48452 82 183 1.3E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_08675 e8bc780c9b4ed357df26419bce67b9b5 452 Pfam PF00202 Aminotransferase class-III 32 443 1.2E-120 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THITH_08675 e8bc780c9b4ed357df26419bce67b9b5 452 PIRSF PIRSF000521 20 418 1.3E-26 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THITH_08675 e8bc780c9b4ed357df26419bce67b9b5 452 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 2 449 49.972 T 13-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 THITH_08675 e8bc780c9b4ed357df26419bce67b9b5 452 SUPERFAMILY SSF53383 10 446 6.65E-128 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_08675 e8bc780c9b4ed357df26419bce67b9b5 452 Gene3D G3DSA:3.40.640.10 67 344 1.5E-160 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_08675 e8bc780c9b4ed357df26419bce67b9b5 452 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 254 291 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THITH_08675 e8bc780c9b4ed357df26419bce67b9b5 452 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 14 446 4.9E-172 T 13-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 THITH_08675 e8bc780c9b4ed357df26419bce67b9b5 452 Gene3D G3DSA:3.90.1150.10 13 439 1.5E-160 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_10260 2e11fa9a4150a8b0807dc31ad74579a1 553 SUPERFAMILY SSF141523 305 459 1.01E-17 T 13-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like THITH_10260 2e11fa9a4150a8b0807dc31ad74579a1 553 Pfam PF03734 L,D-transpeptidase catalytic domain 308 469 8.5E-27 T 13-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 THITH_10260 2e11fa9a4150a8b0807dc31ad74579a1 553 Gene3D G3DSA:2.40.440.10 245 473 9.0E-30 T 13-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like THITH_10260 2e11fa9a4150a8b0807dc31ad74579a1 553 Pfam PF01471 Putative peptidoglycan binding domain 221 279 1.5E-12 T 13-10-2018 IPR002477 Peptidoglycan binding-like THITH_10260 2e11fa9a4150a8b0807dc31ad74579a1 553 SUPERFAMILY SSF47090 205 286 7.85E-17 T 13-10-2018 IPR036365 PGBD-like superfamily THITH_09585 ea02b3ca1d1c19622f0c797561dbb10f 344 SMART SM00771 195 326 3.0E-36 T 13-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 THITH_09585 ea02b3ca1d1c19622f0c797561dbb10f 344 Gene3D G3DSA:3.30.1400.10 193 331 1.5E-42 T 13-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 THITH_09585 ea02b3ca1d1c19622f0c797561dbb10f 344 Pfam PF04354 ZipA, C-terminal FtsZ-binding domain 198 324 1.8E-39 T 13-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 THITH_09585 ea02b3ca1d1c19622f0c797561dbb10f 344 TIGRFAM TIGR02205 septum_zipA: cell division protein ZipA 177 324 8.3E-39 T 13-10-2018 IPR011919 Cell division protein ZipA GO:0016021|GO:0090529 THITH_09585 ea02b3ca1d1c19622f0c797561dbb10f 344 SUPERFAMILY SSF64383 196 328 2.22E-32 T 13-10-2018 IPR036765 ZipA, C-terminal FtsZ-binding domain superfamily GO:0090529 THITH_09585 ea02b3ca1d1c19622f0c797561dbb10f 344 ProDom PD035754 CELL DIVISION MEMBRANE ZIPA SEPTATION TRANSMEMBRANE HOMOLOG INNER CYCLE ZIPA 198 329 6.0E-15 T 13-10-2018 IPR007449 ZipA, C-terminal FtsZ-binding domain GO:0090529 THITH_12100 e443c3aa6fb152f28ac942d034e38c27 427 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 357 387 - T 13-10-2018 IPR030390 RNA methyltransferase TrmA, active site THITH_12100 e443c3aa6fb152f28ac942d034e38c27 427 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 409 419 - T 13-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site THITH_12100 e443c3aa6fb152f28ac942d034e38c27 427 Gene3D G3DSA:3.40.1350.30 115 257 2.2E-104 T 13-10-2018 THITH_12100 e443c3aa6fb152f28ac942d034e38c27 427 Gene3D G3DSA:2.40.50.140 1 67 6.2E-21 T 13-10-2018 THITH_12100 e443c3aa6fb152f28ac942d034e38c27 427 SUPERFAMILY SSF50249 1 46 2.23E-9 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_12100 e443c3aa6fb152f28ac942d034e38c27 427 Hamap MF_01010 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD [rlmD]. 1 427 62.71 T 13-10-2018 IPR001566 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD GO:0003723|GO:0006396|GO:0008173 THITH_12100 e443c3aa6fb152f28ac942d034e38c27 427 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 255 425 5.3E-22 T 13-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 THITH_12100 e443c3aa6fb152f28ac942d034e38c27 427 Gene3D G3DSA:3.40.50.150 68 421 2.2E-104 T 13-10-2018 THITH_12100 e443c3aa6fb152f28ac942d034e38c27 427 SUPERFAMILY SSF53335 55 426 6.26E-74 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_12180 3d6180f937d3c23db99ecdf0366b8de3 192 SUPERFAMILY SSF88659 123 186 2.06E-18 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like THITH_12180 3d6180f937d3c23db99ecdf0366b8de3 192 Pfam PF04542 Sigma-70 region 2 25 92 4.1E-16 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 THITH_12180 3d6180f937d3c23db99ecdf0366b8de3 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 183 1.6E-31 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 THITH_12180 3d6180f937d3c23db99ecdf0366b8de3 192 Pfam PF08281 Sigma-70, region 4 131 181 6.9E-19 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THITH_12180 3d6180f937d3c23db99ecdf0366b8de3 192 TIGRFAM TIGR02939 RpoE_Sigma70: RNA polymerase sigma factor RpoE 1 190 3.6E-93 T 13-10-2018 IPR014286 RNA polymerase sigma-70 RpoE type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THITH_12180 3d6180f937d3c23db99ecdf0366b8de3 192 Gene3D G3DSA:1.10.10.10 126 188 3.7E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_12180 3d6180f937d3c23db99ecdf0366b8de3 192 SUPERFAMILY SSF88946 2 106 7.38E-30 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 THITH_12180 3d6180f937d3c23db99ecdf0366b8de3 192 Gene3D G3DSA:1.10.1740.10 1 121 7.9E-40 T 13-10-2018 THITH_07295 aefdbe0e1a7c9f2290a23e75357f00fc 250 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_07295 aefdbe0e1a7c9f2290a23e75357f00fc 250 Gene3D G3DSA:3.40.50.300 1 248 5.5E-57 T 13-10-2018 THITH_07295 aefdbe0e1a7c9f2290a23e75357f00fc 250 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 2 244 1.4E-105 T 13-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 THITH_07295 aefdbe0e1a7c9f2290a23e75357f00fc 250 SMART SM00382 27 224 2.7E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_07295 aefdbe0e1a7c9f2290a23e75357f00fc 250 SUPERFAMILY SSF52540 2 230 3.69E-41 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_07295 aefdbe0e1a7c9f2290a23e75357f00fc 250 Pfam PF00005 ABC transporter 18 173 4.3E-20 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_06995 968b43bb93edfb77cfcc11cf7526d71e 683 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 8 683 1.1E-262 T 13-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 THITH_06995 968b43bb93edfb77cfcc11cf7526d71e 683 PIRSF PIRSF001265 1 683 2.1E-262 T 13-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 THITH_06995 968b43bb93edfb77cfcc11cf7526d71e 683 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 3 683 25.231 T 13-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 THITH_06995 968b43bb93edfb77cfcc11cf7526d71e 683 Pfam PF03030 Inorganic H+ pyrophosphatase 15 679 4.2E-265 T 13-10-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0016020|GO:1902600 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 THITH_12120 21ed4eee354257c9b4fa6ba526e8b466 250 Gene3D G3DSA:3.20.20.70 1 250 1.5E-97 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_12120 21ed4eee354257c9b4fa6ba526e8b466 250 Hamap MF_00279 Pyridoxine 5'-phosphate synthase [pdxJ]. 1 247 111.347 T 13-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 THITH_12120 21ed4eee354257c9b4fa6ba526e8b466 250 Pfam PF03740 Pyridoxal phosphate biosynthesis protein PdxJ 9 241 3.3E-94 T 13-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 THITH_12120 21ed4eee354257c9b4fa6ba526e8b466 250 TIGRFAM TIGR00559 pdxJ: pyridoxine 5'-phosphate synthase 9 242 2.6E-86 T 13-10-2018 IPR004569 Pyridoxal phosphate (active vitamin B6) biosynthesis PdxJ GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 THITH_12120 21ed4eee354257c9b4fa6ba526e8b466 250 SUPERFAMILY SSF63892 8 245 1.31E-91 T 13-10-2018 IPR036130 Pyridoxine 5'-phosphate synthase GO:0005737|GO:0008615|GO:0033856 KEGG: 00750+2.6.99.2 THITH_06510 ade6fb3014831e3e8b1c5c28b1b2013c 256 Pfam PF00535 Glycosyl transferase family 2 10 150 1.9E-12 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THITH_06510 ade6fb3014831e3e8b1c5c28b1b2013c 256 SUPERFAMILY SSF53448 5 147 1.51E-20 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_06510 ade6fb3014831e3e8b1c5c28b1b2013c 256 Gene3D G3DSA:3.90.550.10 2 180 3.4E-19 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_11445 74834e40781a8f576534faad6af31d92 186 PIRSF PIRSF006806 1 179 1.8E-31 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase THITH_11445 74834e40781a8f576534faad6af31d92 186 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 3 177 9.2E-33 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase THITH_11445 74834e40781a8f576534faad6af31d92 186 SUPERFAMILY SSF100950 2 183 6.98E-47 T 13-10-2018 IPR037171 NagB/RpiA transferase-like THITH_11445 74834e40781a8f576534faad6af31d92 186 Gene3D G3DSA:3.40.50.10420 1 184 1.7E-45 T 13-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily THITH_11445 74834e40781a8f576534faad6af31d92 186 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 2 177 1.6E-41 T 13-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase THITH_00845 1691b5ff419abda4ee6295739e0165f6 347 Gene3D G3DSA:3.40.50.150 160 327 9.3E-86 T 13-10-2018 THITH_00845 1691b5ff419abda4ee6295739e0165f6 347 SUPERFAMILY SSF53335 103 342 1.18E-38 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_00845 1691b5ff419abda4ee6295739e0165f6 347 Pfam PF16864 Dimerisation domain 16 93 1.5E-10 T 13-10-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain THITH_00845 1691b5ff419abda4ee6295739e0165f6 347 PIRSF PIRSF005739 18 337 8.7E-28 T 13-10-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 THITH_00845 1691b5ff419abda4ee6295739e0165f6 347 Pfam PF00891 O-methyltransferase 110 329 2.0E-34 T 13-10-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 THITH_00845 1691b5ff419abda4ee6295739e0165f6 347 SUPERFAMILY SSF46785 11 92 9.35E-9 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_00845 1691b5ff419abda4ee6295739e0165f6 347 Gene3D G3DSA:1.10.10.2650 19 313 9.3E-86 T 13-10-2018 THITH_08815 e3c104b4cfc7b8e13d9741f0d9cdce5e 458 ProSitePatterns PS00163 Fumarate lyases signature. 294 303 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 THITH_08815 e3c104b4cfc7b8e13d9741f0d9cdce5e 458 PRINTS PR00149 Fumarate lyase superfamily signature 294 310 2.0E-16 T 13-10-2018 IPR000362 Fumarate lyase family THITH_08815 e3c104b4cfc7b8e13d9741f0d9cdce5e 458 PRINTS PR00149 Fumarate lyase superfamily signature 163 181 2.0E-16 T 13-10-2018 IPR000362 Fumarate lyase family THITH_08815 e3c104b4cfc7b8e13d9741f0d9cdce5e 458 PRINTS PR00149 Fumarate lyase superfamily signature 251 278 2.0E-16 T 13-10-2018 IPR000362 Fumarate lyase family THITH_08815 e3c104b4cfc7b8e13d9741f0d9cdce5e 458 PRINTS PR00149 Fumarate lyase superfamily signature 117 135 2.0E-16 T 13-10-2018 IPR000362 Fumarate lyase family THITH_08815 e3c104b4cfc7b8e13d9741f0d9cdce5e 458 SUPERFAMILY SSF48557 11 455 5.97E-107 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 THITH_08815 e3c104b4cfc7b8e13d9741f0d9cdce5e 458 Gene3D G3DSA:1.10.275.10 1 117 1.7E-43 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal THITH_08815 e3c104b4cfc7b8e13d9741f0d9cdce5e 458 Gene3D G3DSA:1.10.40.30 382 445 4.6E-151 T 13-10-2018 THITH_08815 e3c104b4cfc7b8e13d9741f0d9cdce5e 458 Pfam PF08328 Adenylosuccinate lyase C-terminal 331 445 2.2E-49 T 13-10-2018 IPR013539 Adenylosuccinate lyase PurB, C-terminal GO:0004018|GO:0006188 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234 THITH_08815 e3c104b4cfc7b8e13d9741f0d9cdce5e 458 Pfam PF00206 Lyase 14 312 4.7E-59 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal THITH_08815 e3c104b4cfc7b8e13d9741f0d9cdce5e 458 Gene3D G3DSA:1.20.200.10 118 446 4.6E-151 T 13-10-2018 THITH_08815 e3c104b4cfc7b8e13d9741f0d9cdce5e 458 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 12 453 4.3E-127 T 13-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THITH_17270 a268b07a600b4a9a8e87ee17fb66fd26 463 Gene3D G3DSA:1.20.1250.20 1 217 1.4E-10 T 13-10-2018 THITH_17270 a268b07a600b4a9a8e87ee17fb66fd26 463 Pfam PF07690 Major Facilitator Superfamily 33 407 1.2E-15 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THITH_17270 a268b07a600b4a9a8e87ee17fb66fd26 463 SUPERFAMILY SSF103473 25 449 2.35E-35 T 13-10-2018 IPR036259 MFS transporter superfamily THITH_17270 a268b07a600b4a9a8e87ee17fb66fd26 463 Gene3D G3DSA:1.20.1250.20 245 452 6.9E-11 T 13-10-2018 THITH_10685 a4ff47d1fa39986c195bc8f64782f452 200 Pfam PF03886 ABC-type transport auxiliary lipoprotein component 46 189 5.3E-12 T 13-10-2018 IPR005586 ABC-type transport auxiliary lipoprotein component THITH_10685 a4ff47d1fa39986c195bc8f64782f452 200 SUPERFAMILY SSF159594 40 197 1.07E-18 T 13-10-2018 THITH_10685 a4ff47d1fa39986c195bc8f64782f452 200 Gene3D G3DSA:3.40.50.10610 33 198 1.6E-5 T 13-10-2018 THITH_11440 0b5fea02db1d96cbe48c0c3dd8698f28 107 Gene3D G3DSA:1.20.5.50 50 105 1.3E-10 T 13-10-2018 THITH_11440 0b5fea02db1d96cbe48c0c3dd8698f28 107 Gene3D G3DSA:1.10.20.30 2 49 7.6E-20 T 13-10-2018 THITH_11440 0b5fea02db1d96cbe48c0c3dd8698f28 107 Pfam PF05164 Cell division protein ZapA 8 90 5.9E-23 T 13-10-2018 IPR007838 Cell division protein ZapA-like THITH_11440 0b5fea02db1d96cbe48c0c3dd8698f28 107 SUPERFAMILY SSF102829 8 95 3.66E-22 T 13-10-2018 IPR036192 Cell division protein ZapA-like superfamily THITH_14935 9dcdf1f4b4ae2a84d64496a423f72ed6 695 SUPERFAMILY SSF110997 613 684 3.4E-5 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 THITH_14935 9dcdf1f4b4ae2a84d64496a423f72ed6 695 Pfam PF13401 AAA domain 49 173 1.4E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_14935 9dcdf1f4b4ae2a84d64496a423f72ed6 695 SUPERFAMILY SSF52540 26 249 5.33E-16 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14935 9dcdf1f4b4ae2a84d64496a423f72ed6 695 Pfam PF05036 Sporulation related domain 613 685 8.5E-10 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 THITH_14935 9dcdf1f4b4ae2a84d64496a423f72ed6 695 Gene3D G3DSA:3.30.70.1070 596 693 2.5E-24 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 THITH_10970 2c194183aa558b4ba089b31f6160fde4 345 Hamap MF_00219 Dihydroorotase [pyrC]. 2 343 46.981 T 13-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_10970 2c194183aa558b4ba089b31f6160fde4 345 PIRSF PIRSF001237 1 344 2.9E-140 T 13-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_10970 2c194183aa558b4ba089b31f6160fde4 345 SUPERFAMILY SSF51556 1 342 1.02E-145 T 13-10-2018 IPR032466 Metal-dependent hydrolase THITH_10970 2c194183aa558b4ba089b31f6160fde4 345 TIGRFAM TIGR00856 pyrC_dimer: dihydroorotase, homodimeric type 4 342 3.4E-135 T 13-10-2018 IPR004721 Dihydroorotase homodimeric type GO:0004151|GO:0019856 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_10970 2c194183aa558b4ba089b31f6160fde4 345 ProSitePatterns PS00483 Dihydroorotase signature 2. 245 256 - T 13-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_10970 2c194183aa558b4ba089b31f6160fde4 345 ProSitePatterns PS00482 Dihydroorotase signature 1. 11 19 - T 13-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 THITH_10970 2c194183aa558b4ba089b31f6160fde4 345 Pfam PF01979 Amidohydrolase family 11 319 7.6E-15 T 13-10-2018 IPR006680 Amidohydrolase-related GO:0016787 THITH_10970 2c194183aa558b4ba089b31f6160fde4 345 Gene3D G3DSA:3.20.20.140 3 343 2.5E-109 T 13-10-2018 THITH_03280 5b558b9a07efdb5b6140e4ee87d996bb 134 Pfam PF02472 Biopolymer transport protein ExbD/TolR 15 130 4.6E-15 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 THITH_02720 f61b25b93da71ba789513d52992af47e 331 Pfam PF01548 Transposase 5 150 3.5E-29 T 13-10-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 THITH_02720 f61b25b93da71ba789513d52992af47e 331 Pfam PF02371 Transposase IS116/IS110/IS902 family 199 282 3.7E-16 T 13-10-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 THITH_16145 739465ef9ef1336cfc600f99dd9d2dda 211 Pfam PF00072 Response regulator receiver domain 7 118 7.7E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_16145 739465ef9ef1336cfc600f99dd9d2dda 211 SUPERFAMILY SSF46894 143 208 5.78E-21 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THITH_16145 739465ef9ef1336cfc600f99dd9d2dda 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 205 4.0E-22 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_16145 739465ef9ef1336cfc600f99dd9d2dda 211 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_16145 739465ef9ef1336cfc600f99dd9d2dda 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 7.3E-15 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_16145 739465ef9ef1336cfc600f99dd9d2dda 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 7.3E-15 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_16145 739465ef9ef1336cfc600f99dd9d2dda 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 7.3E-15 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_16145 739465ef9ef1336cfc600f99dd9d2dda 211 SMART SM00421 149 206 2.4E-25 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_16145 739465ef9ef1336cfc600f99dd9d2dda 211 SUPERFAMILY SSF52172 5 135 7.54E-36 T 13-10-2018 IPR011006 CheY-like superfamily THITH_16145 739465ef9ef1336cfc600f99dd9d2dda 211 SMART SM00448 5 118 1.4E-33 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_16145 739465ef9ef1336cfc600f99dd9d2dda 211 Gene3D G3DSA:3.40.50.12740 5 210 2.0E-68 T 13-10-2018 THITH_06330 a723860068938f475e436be705730728 289 Pfam PF01063 Amino-transferase class IV 29 250 1.3E-47 T 13-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 THITH_06330 a723860068938f475e436be705730728 289 SUPERFAMILY SSF56752 3 273 3.01E-79 T 13-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 THITH_06330 a723860068938f475e436be705730728 289 Gene3D G3DSA:3.20.10.10 119 279 4.2E-58 T 13-10-2018 THITH_06330 a723860068938f475e436be705730728 289 Gene3D G3DSA:3.30.470.10 1 117 2.4E-32 T 13-10-2018 THITH_06330 a723860068938f475e436be705730728 289 ProSitePatterns PS00770 Aminotransferases class-IV signature. 177 206 - T 13-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 THITH_12480 cd9026a52e35e50502a63153c77a6c4f 1091 Pfam PF13419 Haloacid dehalogenase-like hydrolase 506 619 4.9E-7 T 13-10-2018 THITH_12480 cd9026a52e35e50502a63153c77a6c4f 1091 Gene3D G3DSA:3.90.550.10 1 230 1.9E-49 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_12480 cd9026a52e35e50502a63153c77a6c4f 1091 Pfam PF00535 Glycosyl transferase family 2 7 128 1.1E-26 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THITH_12480 cd9026a52e35e50502a63153c77a6c4f 1091 SUPERFAMILY SSF53448 4 222 1.9E-51 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_12480 cd9026a52e35e50502a63153c77a6c4f 1091 Gene3D G3DSA:1.10.150.400 432 518 3.2E-21 T 13-10-2018 THITH_12480 cd9026a52e35e50502a63153c77a6c4f 1091 SUPERFAMILY SSF56784 418 625 2.15E-24 T 13-10-2018 IPR036412 HAD-like superfamily THITH_12480 cd9026a52e35e50502a63153c77a6c4f 1091 Gene3D G3DSA:3.40.50.1000 420 632 3.2E-21 T 13-10-2018 IPR023214 HAD superfamily THITH_11715 2655e5b6dd30df0d055b6340628e88f1 435 SUPERFAMILY SSF52833 34 115 2.3E-9 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_11715 2655e5b6dd30df0d055b6340628e88f1 435 Gene3D G3DSA:3.40.30.10 34 119 2.3E-6 T 13-10-2018 THITH_06940 cfd36c0f3f142c08523b16559e365883 532 Pfam PF01384 Phosphate transporter family 71 520 1.1E-105 T 13-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 SUPERFAMILY SSF52540 143 380 1.17E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 413 430 1.6E-5 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 430 450 1.6E-5 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 PRINTS PR00819 CbxX/CfqX superfamily signature 125 139 1.1E-6 T 13-10-2018 IPR000641 CbxX/CfqX GO:0005524 THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 PRINTS PR00819 CbxX/CfqX superfamily signature 220 239 1.1E-6 T 13-10-2018 IPR000641 CbxX/CfqX GO:0005524 THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 PRINTS PR00819 CbxX/CfqX superfamily signature 165 180 1.1E-6 T 13-10-2018 IPR000641 CbxX/CfqX GO:0005524 THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 PRINTS PR00819 CbxX/CfqX superfamily signature 353 365 1.1E-6 T 13-10-2018 IPR000641 CbxX/CfqX GO:0005524 THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 Pfam PF00158 Sigma-54 interaction domain 144 303 2.2E-48 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 350 359 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 SUPERFAMILY SSF46689 350 450 4.58E-14 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 SUPERFAMILY SSF52172 1 186 9.39E-44 T 13-10-2018 IPR011006 CheY-like superfamily THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 Gene3D G3DSA:3.40.50.2300 2 132 3.2E-36 T 13-10-2018 THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 Pfam PF00072 Response regulator receiver domain 6 114 1.7E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 Pfam PF02954 Bacterial regulatory protein, Fis family 407 445 4.5E-10 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 Gene3D G3DSA:3.40.50.300 133 307 3.6E-51 T 13-10-2018 THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 Gene3D G3DSA:1.10.10.60 394 453 2.2E-16 T 13-10-2018 THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 SMART SM00382 162 301 1.6E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 SMART SM00448 4 116 8.9E-36 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_15560 ac5c9fd6b8e57a679e69c052f9c80d3d 458 Gene3D G3DSA:1.10.8.60 308 387 5.5E-23 T 13-10-2018 THITH_07195 22dc6cc795f3de54f3dd8a70163c8e94 476 SUPERFAMILY SSF103365 7 476 3.4E-159 T 13-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 THITH_07195 22dc6cc795f3de54f3dd8a70163c8e94 476 Pfam PF01139 tRNA-splicing ligase RtcB 45 476 3.2E-149 T 13-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 THITH_07195 22dc6cc795f3de54f3dd8a70163c8e94 476 Gene3D G3DSA:3.90.1860.10 3 476 3.7E-179 T 13-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 THITH_04910 32d7c7678b81c8661a9b40079cf4f879 459 Pfam PF03972 MmgE/PrpD family 5 441 2.0E-106 T 13-10-2018 IPR005656 MmgE/PrpD GO:0016829 THITH_04910 32d7c7678b81c8661a9b40079cf4f879 459 Gene3D G3DSA:1.10.4100.10 1 239 1.2E-63 T 13-10-2018 THITH_04910 32d7c7678b81c8661a9b40079cf4f879 459 Gene3D G3DSA:3.30.1330.120 264 403 2.2E-33 T 13-10-2018 THITH_04910 32d7c7678b81c8661a9b40079cf4f879 459 SUPERFAMILY SSF103378 1 450 7.32E-109 T 13-10-2018 IPR036148 MmgE/PrpD superfamily GO:0016829 THITH_10130 a73bbb74c21fd1b94628859e6455d58c 290 SUPERFAMILY SSF51735 3 275 1.62E-38 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_10130 a73bbb74c21fd1b94628859e6455d58c 290 Gene3D G3DSA:3.40.50.720 3 278 1.4E-34 T 13-10-2018 THITH_10130 a73bbb74c21fd1b94628859e6455d58c 290 Pfam PF01370 NAD dependent epimerase/dehydratase family 80 195 4.4E-5 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 THITH_10130 a73bbb74c21fd1b94628859e6455d58c 290 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 67 1.2E-4 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 THITH_02390 0987c6b7aa04740edd9b8bbd47945779 341 SUPERFAMILY SSF55486 207 311 1.75E-13 T 13-10-2018 THITH_02390 0987c6b7aa04740edd9b8bbd47945779 341 Gene3D G3DSA:3.40.390.10 235 321 5.9E-13 T 13-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 THITH_02390 0987c6b7aa04740edd9b8bbd47945779 341 PRINTS PR00138 Matrixin signature 65 80 3.4E-7 T 13-10-2018 IPR021190 Peptidase M10A GO:0004222|GO:0006508|GO:0008270|GO:0031012 THITH_02390 0987c6b7aa04740edd9b8bbd47945779 341 PRINTS PR00138 Matrixin signature 267 292 3.4E-7 T 13-10-2018 IPR021190 Peptidase M10A GO:0004222|GO:0006508|GO:0008270|GO:0031012 THITH_02390 0987c6b7aa04740edd9b8bbd47945779 341 Pfam PF00413 Matrixin 43 310 9.9E-11 T 13-10-2018 IPR001818 Peptidase M10, metallopeptidase GO:0004222|GO:0006508|GO:0008270|GO:0031012 THITH_15420 430cadd7e94b5a7979d0a4856548e476 440 Pfam PF00696 Amino acid kinase family 28 235 5.4E-23 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 THITH_15420 430cadd7e94b5a7979d0a4856548e476 440 Hamap MF_01105 Amino-acid acetyltransferase [argA]. 1 439 181.319 T 13-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 THITH_15420 430cadd7e94b5a7979d0a4856548e476 440 Gene3D G3DSA:3.40.1160.10 10 291 3.0E-81 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THITH_15420 430cadd7e94b5a7979d0a4856548e476 440 Gene3D G3DSA:3.40.630.30 292 439 7.5E-36 T 13-10-2018 THITH_15420 430cadd7e94b5a7979d0a4856548e476 440 TIGRFAM TIGR01890 N-Ac-Glu-synth: amino-acid N-acetyltransferase 11 439 5.5E-163 T 13-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 THITH_15420 430cadd7e94b5a7979d0a4856548e476 440 PIRSF PIRSF000423 1 439 4.6E-165 T 13-10-2018 IPR010167 Amino-acid N-acetyltransferase GO:0004042|GO:0005737|GO:0006526 KEGG: 00220+2.3.1.1|MetaCyc: PWY-5154 THITH_15420 430cadd7e94b5a7979d0a4856548e476 440 SUPERFAMILY SSF55729 295 414 7.5E-19 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_15420 430cadd7e94b5a7979d0a4856548e476 440 SUPERFAMILY SSF53633 10 290 1.54E-59 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THITH_15420 430cadd7e94b5a7979d0a4856548e476 440 Pfam PF00583 Acetyltransferase (GNAT) family 328 399 2.6E-7 T 13-10-2018 IPR000182 GNAT domain THITH_12540 24cac95e247303d5f3b87b8fc3d9f7ac 648 SMART SM00763 23 384 5.2E-194 T 13-10-2018 IPR013153 PrkA AAA domain THITH_12540 24cac95e247303d5f3b87b8fc3d9f7ac 648 Pfam PF08298 PrkA AAA domain 25 384 6.4E-171 T 13-10-2018 IPR013153 PrkA AAA domain THITH_12540 24cac95e247303d5f3b87b8fc3d9f7ac 648 Pfam PF06798 PrkA serine protein kinase C-terminal domain 387 640 3.6E-73 T 13-10-2018 IPR010650 PrkA C-terminal domain THITH_12540 24cac95e247303d5f3b87b8fc3d9f7ac 648 SUPERFAMILY SSF52540 79 371 7.06E-16 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_12540 24cac95e247303d5f3b87b8fc3d9f7ac 648 PIRSF PIRSF000549 1 648 1.3E-274 T 13-10-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 THITH_13060 9c5f1f4280889934a06cc91a5e34fc76 381 Gene3D G3DSA:1.20.1250.20 188 379 4.2E-43 T 13-10-2018 THITH_13060 9c5f1f4280889934a06cc91a5e34fc76 381 PIRSF PIRSF004925 1 380 5.2E-109 T 13-10-2018 IPR026032 Probable 3-phenylpropionic acid transporter THITH_13060 9c5f1f4280889934a06cc91a5e34fc76 381 SUPERFAMILY SSF103473 7 374 1.13E-47 T 13-10-2018 IPR036259 MFS transporter superfamily THITH_13060 9c5f1f4280889934a06cc91a5e34fc76 381 Gene3D G3DSA:1.20.1250.20 4 184 2.7E-24 T 13-10-2018 THITH_13060 9c5f1f4280889934a06cc91a5e34fc76 381 Pfam PF12832 MFS_1 like family 4 358 8.6E-97 T 13-10-2018 IPR024989 Major facilitator superfamily associated domain THITH_00980 87abf73941f58bddcce2d5d27ae221dc 152 Gene3D G3DSA:3.40.1260.10 18 148 4.8E-18 T 13-10-2018 IPR027396 DsrEFH-like THITH_00980 87abf73941f58bddcce2d5d27ae221dc 152 Pfam PF02635 DsrE/DsrF-like family 42 133 1.6E-7 T 13-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THITH_00980 87abf73941f58bddcce2d5d27ae221dc 152 SUPERFAMILY SSF75169 33 151 1.13E-15 T 13-10-2018 IPR027396 DsrEFH-like THITH_00115 2166b0a1aeb3f5fbf95dbd1464513162 135 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 13 33 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_00115 2166b0a1aeb3f5fbf95dbd1464513162 135 TIGRFAM TIGR01707 gspI: type II secretion system protein I 14 96 2.0E-20 T 13-10-2018 IPR010052 Type II secretion system protein I GO:0008565|GO:0015627|GO:0015628 THITH_00115 2166b0a1aeb3f5fbf95dbd1464513162 135 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 13 34 9.5E-8 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_00115 2166b0a1aeb3f5fbf95dbd1464513162 135 SUPERFAMILY SSF54523 44 133 6.67E-12 T 13-10-2018 THITH_00115 2166b0a1aeb3f5fbf95dbd1464513162 135 Pfam PF07963 Prokaryotic N-terminal methylation motif 9 34 5.3E-9 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_00115 2166b0a1aeb3f5fbf95dbd1464513162 135 Pfam PF02501 Type II secretion system (T2SS), protein I 48 127 1.8E-16 T 13-10-2018 IPR003413 Type II secretion system protein I domain GO:0008565|GO:0015627|GO:0015628 THITH_00115 2166b0a1aeb3f5fbf95dbd1464513162 135 Gene3D G3DSA:3.30.1300.30 42 133 8.8E-10 T 13-10-2018 THITH_13210 75cfe11cad3b8a0546ab1130fe81f5e1 636 SUPERFAMILY SSF54534 262 363 2.75E-26 T 13-10-2018 THITH_13210 75cfe11cad3b8a0546ab1130fe81f5e1 636 Gene3D G3DSA:3.10.50.40 266 362 1.7E-31 T 13-10-2018 THITH_13210 75cfe11cad3b8a0546ab1130fe81f5e1 636 Pfam PF13624 SurA N-terminal domain 1 163 6.3E-46 T 13-10-2018 THITH_13210 75cfe11cad3b8a0546ab1130fe81f5e1 636 Pfam PF00639 PPIC-type PPIASE domain 277 359 2.9E-22 T 13-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 THITH_13210 75cfe11cad3b8a0546ab1130fe81f5e1 636 SUPERFAMILY SSF109998 41 237 2.29E-19 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily THITH_13210 75cfe11cad3b8a0546ab1130fe81f5e1 636 Gene3D G3DSA:1.10.4030.30 41 182 1.4E-9 T 13-10-2018 THITH_13210 75cfe11cad3b8a0546ab1130fe81f5e1 636 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 299 320 - T 13-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 THITH_13210 75cfe11cad3b8a0546ab1130fe81f5e1 636 Gene3D G3DSA:1.10.4030.30 238 374 1.7E-31 T 13-10-2018 THITH_16170 dbcde2fa2924313d92e437126e2bd024 169 SUPERFAMILY SSF82093 29 135 1.31E-38 T 13-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 THITH_16170 dbcde2fa2924313d92e437126e2bd024 169 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 1 140 33.053 T 13-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 THITH_16170 dbcde2fa2924313d92e437126e2bd024 169 Gene3D G3DSA:2.40.50.140 29 136 6.8E-39 T 13-10-2018 THITH_16170 dbcde2fa2924313d92e437126e2bd024 169 Pfam PF03100 CcmE 4 130 4.9E-45 T 13-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 THITH_06895 dbcde2fa2924313d92e437126e2bd024 169 SUPERFAMILY SSF82093 29 135 1.31E-38 T 13-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 THITH_06895 dbcde2fa2924313d92e437126e2bd024 169 Hamap MF_01959 Cytochrome c-type biogenesis protein CcmE [ccmE]. 1 140 33.053 T 13-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 THITH_06895 dbcde2fa2924313d92e437126e2bd024 169 Gene3D G3DSA:2.40.50.140 29 136 6.8E-39 T 13-10-2018 THITH_06895 dbcde2fa2924313d92e437126e2bd024 169 Pfam PF03100 CcmE 4 130 4.9E-45 T 13-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 THITH_06270 cd7e939dc8408db6baa86de8b17244bd 126 SUPERFAMILY SSF110069 5 126 2.22E-50 T 13-10-2018 IPR036767 ApaG domain superfamily THITH_06270 cd7e939dc8408db6baa86de8b17244bd 126 Hamap MF_00791 Protein ApaG [apaG]. 1 126 33.632 T 13-10-2018 IPR023065 Uncharacterised protein family ApaG THITH_06270 cd7e939dc8408db6baa86de8b17244bd 126 Pfam PF04379 ApaG domain 18 103 8.7E-37 T 13-10-2018 IPR007474 ApaG domain THITH_06270 cd7e939dc8408db6baa86de8b17244bd 126 Gene3D G3DSA:2.60.40.1470 2 126 1.9E-50 T 13-10-2018 IPR036767 ApaG domain superfamily THITH_01325 a3b396015cbc14703d2c37c203f059e2 414 Gene3D G3DSA:3.30.460.10 1 121 8.5E-29 T 13-10-2018 THITH_01325 a3b396015cbc14703d2c37c203f059e2 414 Pfam PF01966 HD domain 231 309 6.6E-10 T 13-10-2018 IPR006674 HD domain THITH_01325 a3b396015cbc14703d2c37c203f059e2 414 Hamap MF_01262 CCA-adding enzyme [cca]. 1 401 40.819 T 13-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 THITH_01325 a3b396015cbc14703d2c37c203f059e2 414 SMART SM00471 224 338 1.9E-4 T 13-10-2018 IPR003607 HD/PDEase domain THITH_01325 a3b396015cbc14703d2c37c203f059e2 414 Gene3D G3DSA:1.10.3090.10 122 407 4.8E-39 T 13-10-2018 THITH_01325 a3b396015cbc14703d2c37c203f059e2 414 PIRSF PIRSF000813 1 407 6.8E-180 T 13-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 THITH_01325 a3b396015cbc14703d2c37c203f059e2 414 SUPERFAMILY SSF81891 120 361 9.16E-51 T 13-10-2018 THITH_01325 a3b396015cbc14703d2c37c203f059e2 414 SUPERFAMILY SSF81301 1 119 3.05E-30 T 13-10-2018 THITH_01325 a3b396015cbc14703d2c37c203f059e2 414 Pfam PF01743 Poly A polymerase head domain 3 122 1.0E-17 T 13-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 THITH_01325 a3b396015cbc14703d2c37c203f059e2 414 Hamap MF_01261 Multifunctional CCA protein [cca]. 1 407 51.299 T 13-10-2018 IPR012006 tRNA nucleotidyltransferase, proteobacteria GO:0001680|GO:0003723|GO:0004810|GO:0005524 THITH_01325 a3b396015cbc14703d2c37c203f059e2 414 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 149 211 4.7E-13 T 13-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 THITH_13715 ef3e8f7fb4c70d573ad3a071b73331d7 517 Pfam PF00563 EAL domain 272 504 1.7E-65 T 13-10-2018 IPR001633 EAL domain THITH_13715 ef3e8f7fb4c70d573ad3a071b73331d7 517 SMART SM00052 265 509 1.0E-93 T 13-10-2018 IPR001633 EAL domain THITH_13715 ef3e8f7fb4c70d573ad3a071b73331d7 517 SUPERFAMILY SSF141868 272 516 9.02E-75 T 13-10-2018 IPR035919 EAL domain superfamily THITH_13715 ef3e8f7fb4c70d573ad3a071b73331d7 517 Gene3D G3DSA:3.20.20.450 266 517 3.0E-84 T 13-10-2018 IPR035919 EAL domain superfamily THITH_13715 ef3e8f7fb4c70d573ad3a071b73331d7 517 Pfam PF12792 CSS motif domain associated with EAL 39 168 3.0E-13 T 13-10-2018 IPR024744 Putative cyclic diguanylate phosphodiesterase, CSS motif-containing domain THITH_03230 97914bb392f969c867ff9938e81e5136 251 Pfam PF01925 Sulfite exporter TauE/SafE 9 246 2.0E-31 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 THITH_00070 ed4b86aaffad011136af0f4a526dd36d 309 Gene3D G3DSA:3.40.190.10 5 209 5.2E-84 T 13-10-2018 THITH_00070 ed4b86aaffad011136af0f4a526dd36d 309 SUPERFAMILY SSF54782 219 306 6.02E-27 T 13-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THITH_00070 ed4b86aaffad011136af0f4a526dd36d 309 Gene3D G3DSA:3.40.190.10 102 201 5.2E-84 T 13-10-2018 THITH_00070 ed4b86aaffad011136af0f4a526dd36d 309 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 225 294 1.7E-20 T 13-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THITH_00070 ed4b86aaffad011136af0f4a526dd36d 309 Gene3D G3DSA:3.30.160.40 220 304 1.3E-27 T 13-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THITH_00070 ed4b86aaffad011136af0f4a526dd36d 309 PIRSF PIRSF001438 1 309 2.0E-121 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THITH_00070 ed4b86aaffad011136af0f4a526dd36d 309 PRINTS PR00151 Porphobilinogen deaminase signature 44 64 8.9E-48 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THITH_00070 ed4b86aaffad011136af0f4a526dd36d 309 PRINTS PR00151 Porphobilinogen deaminase signature 123 140 8.9E-48 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THITH_00070 ed4b86aaffad011136af0f4a526dd36d 309 PRINTS PR00151 Porphobilinogen deaminase signature 75 94 8.9E-48 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THITH_00070 ed4b86aaffad011136af0f4a526dd36d 309 PRINTS PR00151 Porphobilinogen deaminase signature 142 159 8.9E-48 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THITH_00070 ed4b86aaffad011136af0f4a526dd36d 309 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 8.9E-48 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THITH_00070 ed4b86aaffad011136af0f4a526dd36d 309 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 5 212 1.6E-78 T 13-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THITH_00070 ed4b86aaffad011136af0f4a526dd36d 309 SUPERFAMILY SSF53850 4 216 1.15E-85 T 13-10-2018 THITH_00070 ed4b86aaffad011136af0f4a526dd36d 309 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 5 296 8.0E-111 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THITH_00070 ed4b86aaffad011136af0f4a526dd36d 309 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 13-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THITH_00070 ed4b86aaffad011136af0f4a526dd36d 309 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 4 296 39.948 T 13-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THITH_10415 1571ae734e0a81077d96123c0e7828d5 170 SMART SM00935 13 167 1.8E-46 T 13-10-2018 IPR005632 Chaperone protein Skp GO:0051082 THITH_10415 1571ae734e0a81077d96123c0e7828d5 170 PIRSF PIRSF002094 1 169 3.5E-47 T 13-10-2018 IPR005632 Chaperone protein Skp GO:0051082 THITH_10415 1571ae734e0a81077d96123c0e7828d5 170 Gene3D G3DSA:3.30.910.20 23 167 1.1E-39 T 13-10-2018 IPR024930 Skp domain superfamily THITH_10415 1571ae734e0a81077d96123c0e7828d5 170 SUPERFAMILY SSF111384 24 166 2.22E-33 T 13-10-2018 THITH_10415 1571ae734e0a81077d96123c0e7828d5 170 Pfam PF03938 Outer membrane protein (OmpH-like) 23 166 4.1E-34 T 13-10-2018 IPR005632 Chaperone protein Skp GO:0051082 THITH_08980 401c81baf5570f21f84d3d0afb488943 219 SMART SM00450 95 216 7.8E-12 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_08980 401c81baf5570f21f84d3d0afb488943 219 Gene3D G3DSA:3.40.250.10 85 219 2.5E-19 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_08980 401c81baf5570f21f84d3d0afb488943 219 SUPERFAMILY SSF52821 102 218 1.09E-19 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_08980 401c81baf5570f21f84d3d0afb488943 219 Pfam PF00581 Rhodanese-like domain 106 212 4.0E-11 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_12225 836f155bb915ca7707c6850f32d473a0 108 Pfam PF02575 YbaB/EbfC DNA-binding family 10 98 1.1E-35 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family THITH_12225 836f155bb915ca7707c6850f32d473a0 108 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 3 104 2.2E-33 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family THITH_12225 836f155bb915ca7707c6850f32d473a0 108 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 4 97 23.451 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family THITH_12225 836f155bb915ca7707c6850f32d473a0 108 Gene3D G3DSA:3.30.1310.10 1 108 2.3E-44 T 13-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily THITH_12225 836f155bb915ca7707c6850f32d473a0 108 PIRSF PIRSF004555 2 108 1.4E-38 T 13-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family THITH_12225 836f155bb915ca7707c6850f32d473a0 108 SUPERFAMILY SSF82607 10 102 5.23E-36 T 13-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily THITH_06135 9fe38d7c6f5c1e1feafc5cf7ff6846c4 314 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 145 309 1.4E-24 T 13-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 THITH_06135 9fe38d7c6f5c1e1feafc5cf7ff6846c4 314 PIRSF PIRSF000102 1 314 1.5E-98 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THITH_06135 9fe38d7c6f5c1e1feafc5cf7ff6846c4 314 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 172 178 - T 13-10-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 THITH_06135 9fe38d7c6f5c1e1feafc5cf7ff6846c4 314 PRINTS PR00086 L-lactate dehydrogenase signature 30 54 2.1E-40 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THITH_06135 9fe38d7c6f5c1e1feafc5cf7ff6846c4 314 PRINTS PR00086 L-lactate dehydrogenase signature 170 183 2.1E-40 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THITH_06135 9fe38d7c6f5c1e1feafc5cf7ff6846c4 314 PRINTS PR00086 L-lactate dehydrogenase signature 5 29 2.1E-40 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THITH_06135 9fe38d7c6f5c1e1feafc5cf7ff6846c4 314 PRINTS PR00086 L-lactate dehydrogenase signature 116 136 2.1E-40 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THITH_06135 9fe38d7c6f5c1e1feafc5cf7ff6846c4 314 PRINTS PR00086 L-lactate dehydrogenase signature 140 158 2.1E-40 T 13-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 THITH_06135 9fe38d7c6f5c1e1feafc5cf7ff6846c4 314 SUPERFAMILY SSF56327 143 308 4.04E-50 T 13-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 THITH_06135 9fe38d7c6f5c1e1feafc5cf7ff6846c4 314 Gene3D G3DSA:3.40.50.720 2 144 2.4E-52 T 13-10-2018 THITH_06135 9fe38d7c6f5c1e1feafc5cf7ff6846c4 314 Gene3D G3DSA:3.90.110.10 145 313 4.3E-55 T 13-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 THITH_06135 9fe38d7c6f5c1e1feafc5cf7ff6846c4 314 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 3 311 37.366 T 13-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 THITH_06135 9fe38d7c6f5c1e1feafc5cf7ff6846c4 314 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 8 304 1.3E-106 T 13-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 THITH_06135 9fe38d7c6f5c1e1feafc5cf7ff6846c4 314 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 6 142 2.6E-40 T 13-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 THITH_06135 9fe38d7c6f5c1e1feafc5cf7ff6846c4 314 SUPERFAMILY SSF51735 3 144 2.59E-47 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_06335 60ee883fcd7bd781929be502a628442d 89 SUPERFAMILY SSF117991 1 89 1.44E-25 T 13-10-2018 IPR027471 YbeD-like domain superfamily THITH_06335 60ee883fcd7bd781929be502a628442d 89 Hamap MF_00659 UPF0250 protein YbeD [ybeD]. 1 89 21.212 T 13-10-2018 IPR007454 Uncharacterised protein family UPF0250 THITH_06335 60ee883fcd7bd781929be502a628442d 89 Gene3D G3DSA:3.30.70.260 1 89 4.2E-30 T 13-10-2018 THITH_06335 60ee883fcd7bd781929be502a628442d 89 Pfam PF04359 Protein of unknown function (DUF493) 7 89 4.5E-28 T 13-10-2018 IPR007454 Uncharacterised protein family UPF0250 THITH_17000 dbe67a2c23a64cad229887981a9b1571 178 Hamap MF_01416 ATP synthase subunit delta [atpD]. 3 178 19.989 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17000 dbe67a2c23a64cad229887981a9b1571 178 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 7 176 4.0E-47 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17000 dbe67a2c23a64cad229887981a9b1571 178 PRINTS PR00125 ATP synthase delta subunit signature 75 86 8.2E-29 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17000 dbe67a2c23a64cad229887981a9b1571 178 PRINTS PR00125 ATP synthase delta subunit signature 136 151 8.2E-29 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17000 dbe67a2c23a64cad229887981a9b1571 178 PRINTS PR00125 ATP synthase delta subunit signature 151 169 8.2E-29 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17000 dbe67a2c23a64cad229887981a9b1571 178 PRINTS PR00125 ATP synthase delta subunit signature 86 100 8.2E-29 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17000 dbe67a2c23a64cad229887981a9b1571 178 PRINTS PR00125 ATP synthase delta subunit signature 7 26 8.2E-29 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17000 dbe67a2c23a64cad229887981a9b1571 178 Pfam PF00213 ATP synthase delta (OSCP) subunit 7 176 4.6E-54 T 13-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17000 dbe67a2c23a64cad229887981a9b1571 178 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 138 157 - T 13-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17000 dbe67a2c23a64cad229887981a9b1571 178 SUPERFAMILY SSF47928 3 105 2.88E-25 T 13-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_17000 dbe67a2c23a64cad229887981a9b1571 178 Gene3D G3DSA:1.10.520.20 2 107 3.6E-30 T 13-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 THITH_11020 e67bc81579b15dbca5680c86cb70d096 601 Pfam PF03600 Citrate transporter 13 546 3.2E-51 T 13-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 THITH_11020 e67bc81579b15dbca5680c86cb70d096 601 SUPERFAMILY SSF116726 225 300 8.24E-10 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_11020 e67bc81579b15dbca5680c86cb70d096 601 Gene3D G3DSA:3.30.70.1450 230 308 7.5E-7 T 13-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 THITH_15600 786fe9d89edf1672927c6b12245129c6 161 Pfam PF04361 Protein of unknown function (DUF494) 5 154 5.9E-54 T 13-10-2018 IPR007456 Smg THITH_15600 786fe9d89edf1672927c6b12245129c6 161 Hamap MF_00598 Protein Smg [smg]. 5 161 28.415 T 13-10-2018 IPR007456 Smg THITH_10185 01cf1c453092873598f75cae9c21cb7a 205 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 30 4.4E-6 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_10185 01cf1c453092873598f75cae9c21cb7a 205 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 9 29 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_10185 01cf1c453092873598f75cae9c21cb7a 205 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 30 3.1E-8 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_08635 df61cb823da14811ffc149c58d540800 183 Pfam PF00156 Phosphoribosyl transferase domain 16 150 1.6E-19 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 THITH_08635 df61cb823da14811ffc149c58d540800 183 Gene3D G3DSA:3.40.50.2020 1 183 2.3E-44 T 13-10-2018 THITH_08635 df61cb823da14811ffc149c58d540800 183 SUPERFAMILY SSF53271 14 181 2.1E-37 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like THITH_14550 80bbe14636d375a2a0a72e18bc188679 246 Pfam PF02167 Cytochrome C1 family 38 245 3.3E-22 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 THITH_14550 80bbe14636d375a2a0a72e18bc188679 246 PRINTS PR00603 Cytochrome C1 signature 46 65 1.1E-9 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 THITH_14550 80bbe14636d375a2a0a72e18bc188679 246 PRINTS PR00603 Cytochrome C1 signature 114 138 1.1E-9 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 THITH_14550 80bbe14636d375a2a0a72e18bc188679 246 PRINTS PR00603 Cytochrome C1 signature 211 226 1.1E-9 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 THITH_14550 80bbe14636d375a2a0a72e18bc188679 246 PRINTS PR00603 Cytochrome C1 signature 192 211 1.1E-9 T 13-10-2018 IPR002326 Cytochrome c1 GO:0009055|GO:0020037 Reactome: R-HSA-1268020|Reactome: R-HSA-611105 THITH_14550 80bbe14636d375a2a0a72e18bc188679 246 SUPERFAMILY SSF46626 24 210 2.19E-41 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_14550 80bbe14636d375a2a0a72e18bc188679 246 Gene3D G3DSA:1.10.760.10 32 211 3.7E-19 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_11990 8e3df4f2b08eb28df94e9239b3051277 130 Pfam PF02635 DsrE/DsrF-like family 1 128 7.7E-30 T 13-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THITH_11990 8e3df4f2b08eb28df94e9239b3051277 130 Gene3D G3DSA:3.40.1260.10 1 130 2.3E-53 T 13-10-2018 IPR027396 DsrEFH-like THITH_11990 8e3df4f2b08eb28df94e9239b3051277 130 SUPERFAMILY SSF75169 1 128 9.08E-40 T 13-10-2018 IPR027396 DsrEFH-like THITH_11990 8e3df4f2b08eb28df94e9239b3051277 130 TIGRFAM TIGR03012 sulf_tusD_dsrE: sulfur relay protein TusD/DsrE 2 128 7.2E-50 T 13-10-2018 IPR017463 Sulphur relay, TusD/DsrE GO:0005737|GO:0008033|GO:0016783 THITH_00170 c5dd996cf4c2f0ba6e57836289b6e271 320 Gene3D G3DSA:3.40.50.720 8 298 1.3E-104 T 13-10-2018 THITH_00170 c5dd996cf4c2f0ba6e57836289b6e271 320 SUPERFAMILY SSF51735 7 312 8.29E-87 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_00170 c5dd996cf4c2f0ba6e57836289b6e271 320 Gene3D G3DSA:3.90.25.10 188 311 1.3E-104 T 13-10-2018 THITH_00170 c5dd996cf4c2f0ba6e57836289b6e271 320 Pfam PF16363 GDP-mannose 4,6 dehydratase 10 306 4.0E-52 T 13-10-2018 IPR016040 NAD(P)-binding domain THITH_02215 d9beb9525db57f33a26a553925074875 79 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 10 54 2.4E-7 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THITH_02215 d9beb9525db57f33a26a553925074875 79 Gene3D G3DSA:2.10.260.10 2 69 3.8E-12 T 13-10-2018 THITH_02215 d9beb9525db57f33a26a553925074875 79 SMART SM00966 10 50 0.0063 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THITH_02215 d9beb9525db57f33a26a553925074875 79 SUPERFAMILY SSF89447 6 68 6.8E-11 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily THITH_02220 7a4ad2e52cf7e2c06981041e06f14051 59 Gene3D G3DSA:3.30.460.10 1 58 1.0E-11 T 13-10-2018 THITH_02220 7a4ad2e52cf7e2c06981041e06f14051 59 SUPERFAMILY SSF81301 5 53 1.21E-11 T 13-10-2018 THITH_02220 7a4ad2e52cf7e2c06981041e06f14051 59 Pfam PF01909 Nucleotidyltransferase domain 4 40 9.2E-7 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THITH_02485 e873384d9c3db3fcfbbcb538cd9fea9b 95 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 1.8E-27 T 13-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 THITH_02485 e873384d9c3db3fcfbbcb538cd9fea9b 95 Gene3D G3DSA:1.10.20.60 1 93 1.7E-23 T 13-10-2018 THITH_02485 e873384d9c3db3fcfbbcb538cd9fea9b 95 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 90 1.1E-16 T 13-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 THITH_02485 e873384d9c3db3fcfbbcb538cd9fea9b 95 SUPERFAMILY SSF141000 2 93 6.41E-28 T 13-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 THITH_02485 e873384d9c3db3fcfbbcb538cd9fea9b 95 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 2 95 22.612 T 13-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 THITH_02610 37814953ec7e108a0b96b78d83372ec4 155 Gene3D G3DSA:3.40.30.10 3 154 1.8E-44 T 13-10-2018 THITH_02610 37814953ec7e108a0b96b78d83372ec4 155 PIRSF PIRSF000239 1 155 6.0E-23 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THITH_02610 37814953ec7e108a0b96b78d83372ec4 155 Pfam PF00578 AhpC/TSA family 10 133 3.3E-30 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THITH_02610 37814953ec7e108a0b96b78d83372ec4 155 SUPERFAMILY SSF52833 4 155 2.44E-44 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_15810 fa4562cae0455e1823ae1fb9c44f296d 162 Gene3D G3DSA:3.40.630.30 1 162 3.0E-45 T 13-10-2018 THITH_15810 fa4562cae0455e1823ae1fb9c44f296d 162 SUPERFAMILY SSF55729 1 162 3.26E-29 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_15810 fa4562cae0455e1823ae1fb9c44f296d 162 Pfam PF13420 Acetyltransferase (GNAT) domain 3 155 1.3E-18 T 13-10-2018 THITH_03740 d4f599e67b8dbaa327eff11c34a43bee 402 Pfam PF04986 Putative transposase 144 330 1.9E-63 T 13-10-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THITH_03740 d4f599e67b8dbaa327eff11c34a43bee 402 Pfam PF14319 Transposase zinc-binding domain 10 118 1.1E-38 T 13-10-2018 IPR026889 Transposase zinc-binding domain THITH_15250 85dc328163d278d768802f034710c328 203 Pfam PF05573 NosL 51 170 3.0E-14 T 13-10-2018 IPR008719 Nitrous oxide reductase accessory protein NosL THITH_15250 85dc328163d278d768802f034710c328 203 SUPERFAMILY SSF160387 75 188 6.02E-27 T 13-10-2018 THITH_15250 85dc328163d278d768802f034710c328 203 Gene3D G3DSA:3.30.70.2050 129 203 1.4E-7 T 13-10-2018 THITH_11050 e23fd653fa12ff0dce42db15623f1d67 95 Gene3D G3DSA:3.30.2310.20 1 84 3.9E-41 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_11050 e23fd653fa12ff0dce42db15623f1d67 95 SUPERFAMILY SSF143011 2 83 7.72E-29 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_11050 e23fd653fa12ff0dce42db15623f1d67 95 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 5 84 5.6E-37 T 13-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 THITH_11050 e23fd653fa12ff0dce42db15623f1d67 95 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 5 84 3.7E-41 T 13-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 THITH_04555 519c4b3acc7a2830c1d02e491e0e9861 81 Gene3D G3DSA:1.10.1220.10 9 47 4.0E-7 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THITH_04555 519c4b3acc7a2830c1d02e491e0e9861 81 SUPERFAMILY SSF47598 4 63 2.45E-12 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 THITH_01330 912a2e9111a1ac2ccc1ac430242f3596 313 Pfam PF13460 NAD(P)H-binding 10 158 1.6E-25 T 13-10-2018 IPR016040 NAD(P)-binding domain THITH_01330 912a2e9111a1ac2ccc1ac430242f3596 313 SUPERFAMILY SSF51735 1 266 2.43E-56 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_01330 912a2e9111a1ac2ccc1ac430242f3596 313 Gene3D G3DSA:3.40.50.720 6 279 5.5E-55 T 13-10-2018 THITH_16845 022ae0d14f8c9b55eef5832f25cfc595 538 SMART SM00304 263 316 7.5E-12 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_16845 022ae0d14f8c9b55eef5832f25cfc595 538 Pfam PF00512 His Kinase A (phospho-acceptor) domain 331 391 3.8E-11 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_16845 022ae0d14f8c9b55eef5832f25cfc595 538 SMART SM00388 329 395 5.1E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_16845 022ae0d14f8c9b55eef5832f25cfc595 538 PRINTS PR00344 Bacterial sensor protein C-terminal signature 490 500 1.5E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_16845 022ae0d14f8c9b55eef5832f25cfc595 538 PRINTS PR00344 Bacterial sensor protein C-terminal signature 501 519 1.5E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_16845 022ae0d14f8c9b55eef5832f25cfc595 538 PRINTS PR00344 Bacterial sensor protein C-terminal signature 472 486 1.5E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_16845 022ae0d14f8c9b55eef5832f25cfc595 538 SUPERFAMILY SSF47384 320 391 5.3E-12 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_16845 022ae0d14f8c9b55eef5832f25cfc595 538 SUPERFAMILY SSF158472 263 314 1.83E-8 T 13-10-2018 THITH_16845 022ae0d14f8c9b55eef5832f25cfc595 538 SUPERFAMILY SSF55874 393 536 3.14E-30 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_16845 022ae0d14f8c9b55eef5832f25cfc595 538 SMART SM00387 436 538 7.6E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_16845 022ae0d14f8c9b55eef5832f25cfc595 538 Gene3D G3DSA:3.30.565.10 411 538 5.9E-28 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_16845 022ae0d14f8c9b55eef5832f25cfc595 538 Pfam PF00672 HAMP domain 263 313 8.5E-10 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_16845 022ae0d14f8c9b55eef5832f25cfc595 538 Gene3D G3DSA:1.10.287.130 318 392 1.5E-18 T 13-10-2018 THITH_16845 022ae0d14f8c9b55eef5832f25cfc595 538 Gene3D G3DSA:1.20.1480.50 223 317 2.4E-10 T 13-10-2018 THITH_16845 022ae0d14f8c9b55eef5832f25cfc595 538 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 437 534 2.0E-16 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_03315 faf0f168053eb52d989d558433bed7df 676 SUPERFAMILY SSF48208 186 655 8.3E-90 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 THITH_03315 faf0f168053eb52d989d558433bed7df 676 TIGRFAM TIGR01561 gde_arch: putative glycogen debranching enzyme, archaeal type 20 597 5.2E-114 T 13-10-2018 IPR006451 Glycogen debranching enzyme, archaeal type THITH_03315 faf0f168053eb52d989d558433bed7df 676 Gene3D G3DSA:1.50.10.10 316 652 2.5E-46 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 THITH_03315 faf0f168053eb52d989d558433bed7df 676 Pfam PF12439 Glycogen debranching enzyme N terminal 19 237 9.4E-66 T 13-10-2018 IPR024742 Glycogen debranching enzyme, bacterial and archaeal type, N-terminal THITH_03315 faf0f168053eb52d989d558433bed7df 676 Pfam PF06202 Amylo-alpha-1,6-glucosidase 289 652 4.1E-125 T 13-10-2018 IPR032790 Glycogen debranching enzyme, C-terminal KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-6798695|Reactome: R-HSA-70221 THITH_12875 2d5a6685dcd616fc761ec2fc6641c0d6 482 PIRSF PIRSF005522 1 482 3.9E-220 T 13-10-2018 IPR016450 Uncharacterised conserved protein UCP005522 THITH_12875 2d5a6685dcd616fc761ec2fc6641c0d6 482 SUPERFAMILY SSF56059 35 471 7.3E-63 T 13-10-2018 THITH_12875 2d5a6685dcd616fc761ec2fc6641c0d6 482 Gene3D G3DSA:3.40.50.11290 219 316 3.1E-39 T 13-10-2018 THITH_12875 2d5a6685dcd616fc761ec2fc6641c0d6 482 Gene3D G3DSA:3.30.1490.270 353 413 5.9E-27 T 13-10-2018 THITH_12875 2d5a6685dcd616fc761ec2fc6641c0d6 482 Pfam PF14403 Circularly permuted ATP-grasp type 2 80 456 6.6E-163 T 13-10-2018 IPR025841 Circularly permuted ATP-grasp type 2 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 Pfam PF00330 Aconitase family (aconitate hydratase) 64 587 4.5E-180 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 Gene3D G3DSA:3.30.499.20 3 369 4.8E-158 T 13-10-2018 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 ProSitePatterns PS00450 Aconitase family signature 1. 452 468 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 Pfam PF00694 Aconitase C-terminal domain 717 843 5.9E-46 T 13-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 Gene3D G3DSA:1.10.1440.20 616 677 3.1E-18 T 13-10-2018 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 SUPERFAMILY SSF53732 24 651 1.2E-220 T 13-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 SUPERFAMILY SSF52016 657 914 1.37E-87 T 13-10-2018 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 Gene3D G3DSA:3.30.499.10 370 615 5.4E-98 T 13-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 Gene3D G3DSA:3.20.19.10 679 916 7.4E-109 T 13-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 ProSitePatterns PS01244 Aconitase family signature 2. 518 531 - T 13-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 28 914 0.0 T 13-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 PRINTS PR00415 Aconitase family signature 199 212 6.9E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 PRINTS PR00415 Aconitase family signature 456 467 6.9E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 PRINTS PR00415 Aconitase family signature 369 383 6.9E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 PRINTS PR00415 Aconitase family signature 289 302 6.9E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 PRINTS PR00415 Aconitase family signature 275 288 6.9E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 PRINTS PR00415 Aconitase family signature 141 154 6.9E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 PRINTS PR00415 Aconitase family signature 518 531 6.9E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 PRINTS PR00415 Aconitase family signature 165 173 6.9E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_08790 5a2d74f4974bd2066393804324d92a3d 916 PRINTS PR00415 Aconitase family signature 213 228 6.9E-43 T 13-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 THITH_08945 0f0e87d7a60038a7b1525ee973c10546 476 Gene3D G3DSA:1.10.287.130 193 309 3.1E-23 T 13-10-2018 THITH_08945 0f0e87d7a60038a7b1525ee973c10546 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 424 442 6.4E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_08945 0f0e87d7a60038a7b1525ee973c10546 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 447 460 6.4E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_08945 0f0e87d7a60038a7b1525ee973c10546 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 417 6.4E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_08945 0f0e87d7a60038a7b1525ee973c10546 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 403 6.4E-10 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_08945 0f0e87d7a60038a7b1525ee973c10546 476 SMART SM00388 243 309 6.7E-16 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_08945 0f0e87d7a60038a7b1525ee973c10546 476 SUPERFAMILY SSF158472 192 239 2.62E-5 T 13-10-2018 THITH_08945 0f0e87d7a60038a7b1525ee973c10546 476 SMART SM00304 189 242 6.2E-9 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_08945 0f0e87d7a60038a7b1525ee973c10546 476 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 309 1.3E-12 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_08945 0f0e87d7a60038a7b1525ee973c10546 476 TIGRFAM TIGR01386 cztS_silS_copS: heavy metal sensor kinase 8 460 1.5E-146 T 13-10-2018 IPR006290 Heavy metal sensor kinase GO:0000160|GO:0004673|GO:0016020 THITH_08945 0f0e87d7a60038a7b1525ee973c10546 476 SMART SM00387 352 463 9.7E-32 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_08945 0f0e87d7a60038a7b1525ee973c10546 476 SUPERFAMILY SSF55874 299 461 6.55E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_08945 0f0e87d7a60038a7b1525ee973c10546 476 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 352 460 5.5E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_08945 0f0e87d7a60038a7b1525ee973c10546 476 Gene3D G3DSA:3.30.565.10 316 465 4.4E-35 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_08945 0f0e87d7a60038a7b1525ee973c10546 476 SUPERFAMILY SSF47384 226 309 1.14E-16 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_14245 89e89eb964a9a90f4f850f31ff33a3f0 88 Pfam PF00366 Ribosomal protein S17 14 81 7.4E-29 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14245 89e89eb964a9a90f4f850f31ff33a3f0 88 ProSitePatterns PS00056 Ribosomal protein S17 signature. 60 72 - T 13-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14245 89e89eb964a9a90f4f850f31ff33a3f0 88 SUPERFAMILY SSF50249 10 86 3.08E-29 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_14245 89e89eb964a9a90f4f850f31ff33a3f0 88 Gene3D G3DSA:2.40.50.140 5 87 7.6E-32 T 13-10-2018 THITH_14245 89e89eb964a9a90f4f850f31ff33a3f0 88 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 9 84 23.032 T 13-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14245 89e89eb964a9a90f4f850f31ff33a3f0 88 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 10 80 1.0E-22 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14245 89e89eb964a9a90f4f850f31ff33a3f0 88 PRINTS PR00973 Ribosomal protein S17 family signature 28 51 1.2E-11 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14245 89e89eb964a9a90f4f850f31ff33a3f0 88 PRINTS PR00973 Ribosomal protein S17 family signature 70 77 1.2E-11 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14245 89e89eb964a9a90f4f850f31ff33a3f0 88 PRINTS PR00973 Ribosomal protein S17 family signature 60 70 1.2E-11 T 13-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14245 89e89eb964a9a90f4f850f31ff33a3f0 88 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 10 80 6.9E-32 T 13-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_04270 b9e4ff7e7589c04e46fbcaeb0813544b 521 Gene3D G3DSA:3.30.300.30 411 516 9.1E-27 T 13-10-2018 THITH_04270 b9e4ff7e7589c04e46fbcaeb0813544b 521 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 13-10-2018 IPR020845 AMP-binding, conserved site THITH_04270 b9e4ff7e7589c04e46fbcaeb0813544b 521 Gene3D G3DSA:3.40.50.12780 3 410 7.1E-113 T 13-10-2018 THITH_04270 b9e4ff7e7589c04e46fbcaeb0813544b 521 Pfam PF00501 AMP-binding enzyme 18 418 6.1E-97 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 THITH_04270 b9e4ff7e7589c04e46fbcaeb0813544b 521 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 497 2.5E-11 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain THITH_04270 b9e4ff7e7589c04e46fbcaeb0813544b 521 SUPERFAMILY SSF56801 7 509 3.4E-137 T 13-10-2018 THITH_04270 b9e4ff7e7589c04e46fbcaeb0813544b 521 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 32 442 8.9E-109 T 13-10-2018 IPR010071 Amino acid adenylation domain THITH_05980 6350ffb8c3e83e10a7ede4ac8bef2510 163 Pfam PF13470 PIN domain 2 115 6.5E-11 T 13-10-2018 IPR002716 PIN domain THITH_05980 6350ffb8c3e83e10a7ede4ac8bef2510 163 Gene3D G3DSA:3.40.50.1010 1 127 3.1E-9 T 13-10-2018 THITH_05980 6350ffb8c3e83e10a7ede4ac8bef2510 163 SUPERFAMILY SSF88723 1 127 2.29E-15 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_14335 5c0e8810522013817554f208d6f9b888 176 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 26.048 T 13-10-2018 IPR022973 Ribosomal protein L10 THITH_14335 5c0e8810522013817554f208d6f9b888 176 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 13-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14335 5c0e8810522013817554f208d6f9b888 176 Pfam PF00466 Ribosomal protein L10 6 101 1.3E-23 T 13-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 THITH_14335 5c0e8810522013817554f208d6f9b888 176 Gene3D G3DSA:3.30.70.1730 5 134 1.8E-30 T 13-10-2018 THITH_14335 5c0e8810522013817554f208d6f9b888 176 SUPERFAMILY SSF160369 4 172 7.72E-51 T 13-10-2018 THITH_03955 5674d11366fb3f744a86dd0aadd821e6 230 Gene3D G3DSA:3.90.1680.10 1 222 4.7E-62 T 13-10-2018 IPR036590 SOS response associated peptidase-like THITH_03955 5674d11366fb3f744a86dd0aadd821e6 230 SUPERFAMILY SSF143081 2 222 2.49E-58 T 13-10-2018 IPR036590 SOS response associated peptidase-like THITH_03955 5674d11366fb3f744a86dd0aadd821e6 230 Pfam PF02586 SOS response associated peptidase (SRAP) 1 210 4.1E-52 T 13-10-2018 IPR003738 SOS response associated peptidase (SRAP) THITH_14865 5a0941e0db4d0485625bdc2200636b82 184 Pfam PF01202 Shikimate kinase 10 166 6.0E-50 T 13-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 THITH_14865 5a0941e0db4d0485625bdc2200636b82 184 ProSitePatterns PS01128 Shikimate kinase signature. 57 82 - T 13-10-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 THITH_14865 5a0941e0db4d0485625bdc2200636b82 184 Hamap MF_00109 Shikimate kinase [aroK]. 1 167 28.823 T 13-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 THITH_14865 5a0941e0db4d0485625bdc2200636b82 184 SUPERFAMILY SSF52540 3 165 1.74E-29 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14865 5a0941e0db4d0485625bdc2200636b82 184 PRINTS PR01100 Shikimate kinase family signature 94 111 6.3E-23 T 13-10-2018 THITH_14865 5a0941e0db4d0485625bdc2200636b82 184 PRINTS PR01100 Shikimate kinase family signature 28 41 6.3E-23 T 13-10-2018 THITH_14865 5a0941e0db4d0485625bdc2200636b82 184 PRINTS PR01100 Shikimate kinase family signature 74 83 6.3E-23 T 13-10-2018 THITH_14865 5a0941e0db4d0485625bdc2200636b82 184 PRINTS PR01100 Shikimate kinase family signature 56 64 6.3E-23 T 13-10-2018 THITH_14865 5a0941e0db4d0485625bdc2200636b82 184 PRINTS PR01100 Shikimate kinase family signature 4 19 6.3E-23 T 13-10-2018 THITH_14865 5a0941e0db4d0485625bdc2200636b82 184 Gene3D G3DSA:3.40.50.300 1 174 8.0E-54 T 13-10-2018 THITH_07700 c8c0b0aec3038d0bfa91f78c0d1094d1 608 Gene3D G3DSA:1.10.150.20 552 606 1.6E-22 T 13-10-2018 THITH_07700 c8c0b0aec3038d0bfa91f78c0d1094d1 608 SUPERFAMILY SSF82771 20 104 1.31E-23 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 THITH_07700 c8c0b0aec3038d0bfa91f78c0d1094d1 608 Pfam PF14520 Helix-hairpin-helix domain 554 603 2.1E-8 T 13-10-2018 THITH_07700 c8c0b0aec3038d0bfa91f78c0d1094d1 608 Pfam PF02151 UvrB/uvrC motif 207 241 6.7E-9 T 13-10-2018 IPR001943 UVR domain GO:0005515 THITH_07700 c8c0b0aec3038d0bfa91f78c0d1094d1 608 SUPERFAMILY SSF46600 195 246 9.94E-13 T 13-10-2018 IPR036876 UVR domain superfamily THITH_07700 c8c0b0aec3038d0bfa91f78c0d1094d1 608 SMART SM00465 20 102 4.9E-20 T 13-10-2018 IPR000305 GIY-YIG endonuclease THITH_07700 c8c0b0aec3038d0bfa91f78c0d1094d1 608 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 13 586 1.7E-182 T 13-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 THITH_07700 c8c0b0aec3038d0bfa91f78c0d1094d1 608 SMART SM00278 585 604 5.6 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THITH_07700 c8c0b0aec3038d0bfa91f78c0d1094d1 608 SMART SM00278 553 572 2.2 T 13-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 THITH_07700 c8c0b0aec3038d0bfa91f78c0d1094d1 608 Pfam PF01541 GIY-YIG catalytic domain 22 97 4.0E-10 T 13-10-2018 IPR000305 GIY-YIG endonuclease THITH_07700 c8c0b0aec3038d0bfa91f78c0d1094d1 608 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 384 539 5.5E-52 T 13-10-2018 IPR001162 UvrC family homology region THITH_07700 c8c0b0aec3038d0bfa91f78c0d1094d1 608 SUPERFAMILY SSF47781 518 607 1.56E-24 T 13-10-2018 IPR010994 RuvA domain 2-like THITH_07700 c8c0b0aec3038d0bfa91f78c0d1094d1 608 Hamap MF_00203 UvrABC system protein C [uvrC]. 7 604 28.325 T 13-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 THITH_07700 c8c0b0aec3038d0bfa91f78c0d1094d1 608 Gene3D G3DSA:3.40.1440.10 9 106 1.1E-31 T 13-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 THITH_07700 c8c0b0aec3038d0bfa91f78c0d1094d1 608 Gene3D G3DSA:3.30.420.340 378 539 6.7E-51 T 13-10-2018 IPR038476 UvrC homology region 2 superfamily THITH_07870 13fce57ea06c8dceef0b7fc35d9f795a 322 Gene3D G3DSA:3.90.226.10 76 275 1.6E-60 T 13-10-2018 THITH_07870 13fce57ea06c8dceef0b7fc35d9f795a 322 Gene3D G3DSA:3.40.1750.20 177 243 1.6E-60 T 13-10-2018 THITH_07870 13fce57ea06c8dceef0b7fc35d9f795a 322 Pfam PF01343 Peptidase family S49 139 278 6.3E-31 T 13-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 THITH_07870 13fce57ea06c8dceef0b7fc35d9f795a 322 SUPERFAMILY SSF52096 68 273 2.07E-39 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THITH_14180 710378cc2f36fb89558fc74e26b8c86e 118 SUPERFAMILY SSF46946 2 114 3.53E-45 T 13-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 THITH_14180 710378cc2f36fb89558fc74e26b8c86e 118 Gene3D G3DSA:4.10.910.10 72 118 5.8E-26 T 13-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14180 710378cc2f36fb89558fc74e26b8c86e 118 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 1.6E-52 T 13-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14180 710378cc2f36fb89558fc74e26b8c86e 118 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 27.048 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14180 710378cc2f36fb89558fc74e26b8c86e 118 Pfam PF00416 Ribosomal protein S13/S18 65 108 3.0E-17 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14180 710378cc2f36fb89558fc74e26b8c86e 118 Pfam PF00416 Ribosomal protein S13/S18 3 62 2.9E-15 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14180 710378cc2f36fb89558fc74e26b8c86e 118 PIRSF PIRSF002134 1 118 2.2E-41 T 13-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14180 710378cc2f36fb89558fc74e26b8c86e 118 Gene3D G3DSA:1.10.8.50 1 71 9.4E-28 T 13-10-2018 THITH_14180 710378cc2f36fb89558fc74e26b8c86e 118 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 13-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_05075 1d9ff9eedd6723c233084396d2d08fcd 400 PIRSF PIRSF000524 6 395 4.8E-120 T 13-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 THITH_05075 1d9ff9eedd6723c233084396d2d08fcd 400 SUPERFAMILY SSF53383 10 375 1.75E-109 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_05075 1d9ff9eedd6723c233084396d2d08fcd 400 Gene3D G3DSA:3.40.640.10 22 271 4.4E-146 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_05075 1d9ff9eedd6723c233084396d2d08fcd 400 Pfam PF00266 Aminotransferase class-V 13 338 6.5E-37 T 13-10-2018 IPR000192 Aminotransferase class V domain THITH_05075 1d9ff9eedd6723c233084396d2d08fcd 400 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 189 209 - T 13-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site THITH_05075 1d9ff9eedd6723c233084396d2d08fcd 400 Gene3D G3DSA:3.90.1150.10 12 369 4.4E-146 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_10620 2e8c65dfc48c976058999119b55579e8 339 Pfam PF12706 Beta-lactamase superfamily domain 44 103 1.3E-6 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_10620 2e8c65dfc48c976058999119b55579e8 339 SUPERFAMILY SSF56281 25 337 6.72E-37 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_00015 fbd6d44a79a1e08a49176d547872b78c 365 Pfam PF02463 RecF/RecN/SMC N terminal domain 6 337 7.5E-12 T 13-10-2018 IPR003395 RecF/RecN/SMC, N-terminal THITH_00015 fbd6d44a79a1e08a49176d547872b78c 365 Gene3D G3DSA:3.40.50.300 8 333 4.4E-61 T 13-10-2018 THITH_00015 fbd6d44a79a1e08a49176d547872b78c 365 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 365 64.646 T 13-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 THITH_00015 fbd6d44a79a1e08a49176d547872b78c 365 Gene3D G3DSA:1.20.1050.90 118 298 4.4E-61 T 13-10-2018 THITH_00015 fbd6d44a79a1e08a49176d547872b78c 365 SUPERFAMILY SSF52540 1 344 2.02E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00015 fbd6d44a79a1e08a49176d547872b78c 365 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 5 356 4.5E-62 T 13-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 THITH_08240 53010e7ae8a115c84489ee38ef814439 274 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 55 69 - T 13-10-2018 IPR019775 WD40 repeat, conserved site THITH_08240 53010e7ae8a115c84489ee38ef814439 274 PRINTS PR00319 Beta G protein (transducin) signature 116 131 2.7E-6 T 13-10-2018 IPR001632 G-protein, beta subunit THITH_08240 53010e7ae8a115c84489ee38ef814439 274 PRINTS PR00319 Beta G protein (transducin) signature 78 94 2.7E-6 T 13-10-2018 IPR001632 G-protein, beta subunit THITH_08240 53010e7ae8a115c84489ee38ef814439 274 PRINTS PR00319 Beta G protein (transducin) signature 134 151 2.7E-6 T 13-10-2018 IPR001632 G-protein, beta subunit THITH_08240 53010e7ae8a115c84489ee38ef814439 274 PRINTS PR00319 Beta G protein (transducin) signature 97 111 2.7E-6 T 13-10-2018 IPR001632 G-protein, beta subunit THITH_08240 53010e7ae8a115c84489ee38ef814439 274 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 139 153 - T 13-10-2018 IPR019775 WD40 repeat, conserved site THITH_08240 53010e7ae8a115c84489ee38ef814439 274 Pfam PF00400 WD domain, G-beta repeat 30 68 7.1E-12 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08240 53010e7ae8a115c84489ee38ef814439 274 Pfam PF00400 WD domain, G-beta repeat 156 194 2.1E-8 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08240 53010e7ae8a115c84489ee38ef814439 274 Pfam PF00400 WD domain, G-beta repeat 72 110 6.1E-11 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08240 53010e7ae8a115c84489ee38ef814439 274 Pfam PF00400 WD domain, G-beta repeat 114 152 4.8E-10 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08240 53010e7ae8a115c84489ee38ef814439 274 Pfam PF00400 WD domain, G-beta repeat 1 26 1.0E-6 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08240 53010e7ae8a115c84489ee38ef814439 274 Gene3D G3DSA:2.130.10.10 161 250 8.1E-16 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 THITH_08240 53010e7ae8a115c84489ee38ef814439 274 SMART SM00320 1 26 1.6 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08240 53010e7ae8a115c84489ee38ef814439 274 SMART SM00320 71 110 1.3E-13 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08240 53010e7ae8a115c84489ee38ef814439 274 SMART SM00320 113 152 4.7E-14 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08240 53010e7ae8a115c84489ee38ef814439 274 SMART SM00320 29 68 7.1E-14 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08240 53010e7ae8a115c84489ee38ef814439 274 SMART SM00320 155 194 1.1E-11 T 13-10-2018 IPR001680 WD40 repeat GO:0005515 THITH_08240 53010e7ae8a115c84489ee38ef814439 274 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 13 27 - T 13-10-2018 IPR019775 WD40 repeat, conserved site THITH_08240 53010e7ae8a115c84489ee38ef814439 274 Gene3D G3DSA:2.130.10.10 78 160 2.5E-38 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 THITH_08240 53010e7ae8a115c84489ee38ef814439 274 Gene3D G3DSA:2.130.10.10 1 77 9.3E-35 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 THITH_08240 53010e7ae8a115c84489ee38ef814439 274 PRINTS PR00320 G protein beta WD-40 repeat signature 97 111 9.6E-9 T 13-10-2018 IPR020472 G-protein beta WD-40 repeat THITH_08240 53010e7ae8a115c84489ee38ef814439 274 PRINTS PR00320 G protein beta WD-40 repeat signature 13 27 9.6E-9 T 13-10-2018 IPR020472 G-protein beta WD-40 repeat THITH_08240 53010e7ae8a115c84489ee38ef814439 274 PRINTS PR00320 G protein beta WD-40 repeat signature 55 69 9.6E-9 T 13-10-2018 IPR020472 G-protein beta WD-40 repeat THITH_08240 53010e7ae8a115c84489ee38ef814439 274 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 97 111 - T 13-10-2018 IPR019775 WD40 repeat, conserved site THITH_08240 53010e7ae8a115c84489ee38ef814439 274 SUPERFAMILY SSF50978 1 227 3.11E-79 T 13-10-2018 IPR036322 WD40-repeat-containing domain superfamily GO:0005515 THITH_08240 53010e7ae8a115c84489ee38ef814439 274 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 181 195 - T 13-10-2018 IPR019775 WD40 repeat, conserved site THITH_13325 8aac722751a7f7aec0973dae3d3c3dd4 223 Pfam PF00005 ABC transporter 24 172 5.6E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_13325 8aac722751a7f7aec0973dae3d3c3dd4 223 SMART SM00382 32 221 6.5E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_13325 8aac722751a7f7aec0973dae3d3c3dd4 223 Gene3D G3DSA:3.40.50.300 1 223 4.0E-64 T 13-10-2018 THITH_13325 8aac722751a7f7aec0973dae3d3c3dd4 223 SUPERFAMILY SSF52540 4 222 8.19E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13325 8aac722751a7f7aec0973dae3d3c3dd4 223 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_02105 a4f9daede4d7b8694c04766a5e97b0de 198 SUPERFAMILY SSF54862 1 182 5.76E-49 T 13-10-2018 THITH_02105 a4f9daede4d7b8694c04766a5e97b0de 198 Gene3D G3DSA:3.30.70.20 61 120 1.4E-33 T 13-10-2018 THITH_02105 a4f9daede4d7b8694c04766a5e97b0de 198 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 87 98 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_02105 a4f9daede4d7b8694c04766a5e97b0de 198 Gene3D G3DSA:3.30.70.20 5 171 1.4E-33 T 13-10-2018 THITH_02105 a4f9daede4d7b8694c04766a5e97b0de 198 Pfam PF12838 4Fe-4S dicluster domain 87 161 1.6E-9 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_02105 a4f9daede4d7b8694c04766a5e97b0de 198 PRINTS PR00354 7Fe ferredoxin signature 82 99 5.5E-5 T 13-10-2018 IPR000813 7Fe ferredoxin GO:0009055 THITH_02105 a4f9daede4d7b8694c04766a5e97b0de 198 PRINTS PR00354 7Fe ferredoxin signature 65 75 5.5E-5 T 13-10-2018 IPR000813 7Fe ferredoxin GO:0009055 THITH_02105 a4f9daede4d7b8694c04766a5e97b0de 198 PRINTS PR00354 7Fe ferredoxin signature 55 65 5.5E-5 T 13-10-2018 IPR000813 7Fe ferredoxin GO:0009055 THITH_08440 da377ff57416760f46e4f8f1e5b8b6b9 387 SMART SM00722 147 325 1.2E-17 T 13-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain THITH_08440 da377ff57416760f46e4f8f1e5b8b6b9 387 SMART SM00722 1 141 2.3E-10 T 13-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain THITH_08440 da377ff57416760f46e4f8f1e5b8b6b9 387 Pfam PF05048 Periplasmic copper-binding protein (NosD) 99 341 5.8E-62 T 13-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 THITH_08440 da377ff57416760f46e4f8f1e5b8b6b9 387 SUPERFAMILY SSF51126 1 366 7.92E-62 T 13-10-2018 IPR011050 Pectin lyase fold/virulence factor THITH_08440 da377ff57416760f46e4f8f1e5b8b6b9 387 TIGRFAM TIGR04247 NosD_copper_fam: nitrous oxide reductase family maturation protein NosD 1 378 4.1E-143 T 13-10-2018 IPR026464 Nitrous oxide reductase family maturation protein NosD THITH_08440 da377ff57416760f46e4f8f1e5b8b6b9 387 Gene3D G3DSA:2.160.20.10 24 144 2.7E-14 T 13-10-2018 IPR012334 Pectin lyase fold THITH_08440 da377ff57416760f46e4f8f1e5b8b6b9 387 Gene3D G3DSA:2.160.20.10 145 312 4.3E-19 T 13-10-2018 IPR012334 Pectin lyase fold THITH_08440 da377ff57416760f46e4f8f1e5b8b6b9 387 SMART SM00710 165 186 3200.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat THITH_08440 da377ff57416760f46e4f8f1e5b8b6b9 387 SMART SM00710 187 209 2800.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat THITH_08440 da377ff57416760f46e4f8f1e5b8b6b9 387 SMART SM00710 91 120 32.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat THITH_08440 da377ff57416760f46e4f8f1e5b8b6b9 387 SMART SM00710 210 240 570.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat THITH_08440 da377ff57416760f46e4f8f1e5b8b6b9 387 SMART SM00710 69 90 540.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat THITH_08440 da377ff57416760f46e4f8f1e5b8b6b9 387 SMART SM00710 143 164 570.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat THITH_08440 da377ff57416760f46e4f8f1e5b8b6b9 387 SMART SM00710 121 142 1.1 T 13-10-2018 IPR006626 Parallel beta-helix repeat THITH_08440 da377ff57416760f46e4f8f1e5b8b6b9 387 SMART SM00710 39 67 530.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat THITH_08440 da377ff57416760f46e4f8f1e5b8b6b9 387 SMART SM00710 250 271 210.0 T 13-10-2018 IPR006626 Parallel beta-helix repeat THITH_04835 f791eff17129bd52a1b70ecbfadcbb14 410 SUPERFAMILY SSF53383 4 389 2.86E-110 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_04835 f791eff17129bd52a1b70ecbfadcbb14 410 Pfam PF00155 Aminotransferase class I and II 32 376 1.2E-58 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THITH_04835 f791eff17129bd52a1b70ecbfadcbb14 410 Gene3D G3DSA:3.90.1150.10 289 387 2.0E-131 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_04835 f791eff17129bd52a1b70ecbfadcbb14 410 Gene3D G3DSA:3.40.640.10 64 288 2.0E-131 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_02280 01116a39c6992f5450410f2369c46b20 139 Gene3D G3DSA:3.30.700.10 7 138 6.5E-23 T 13-10-2018 THITH_02280 01116a39c6992f5450410f2369c46b20 139 SUPERFAMILY SSF54523 7 122 2.75E-22 T 13-10-2018 THITH_02280 01116a39c6992f5450410f2369c46b20 139 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 27 8.1E-10 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_02280 01116a39c6992f5450410f2369c46b20 139 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_02280 01116a39c6992f5450410f2369c46b20 139 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 27 1.9E-9 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_02280 01116a39c6992f5450410f2369c46b20 139 Pfam PF16732 Type IV minor pilin ComP, DNA uptake sequence receptor 28 121 1.5E-18 T 13-10-2018 IPR031982 Type IV minor pilin ComP THITH_08435 f0ce95b4908809a36088990463ae30d7 303 SUPERFAMILY SSF52540 4 219 1.94E-59 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_08435 f0ce95b4908809a36088990463ae30d7 303 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_08435 f0ce95b4908809a36088990463ae30d7 303 Gene3D G3DSA:3.40.50.300 1 226 1.1E-63 T 13-10-2018 THITH_08435 f0ce95b4908809a36088990463ae30d7 303 SMART SM00382 28 216 1.4E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_08435 f0ce95b4908809a36088990463ae30d7 303 Pfam PF00005 ABC transporter 19 159 3.0E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_06685 2245d1a94568b8ce4921edb2b3e21fa3 157 Pfam PF03168 Late embryogenesis abundant protein 53 138 5.5E-11 T 13-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup THITH_06685 2245d1a94568b8ce4921edb2b3e21fa3 157 SMART SM00769 32 153 6.6E-9 T 13-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 THITH_06685 2245d1a94568b8ce4921edb2b3e21fa3 157 SUPERFAMILY SSF117070 8 137 8.11E-20 T 13-10-2018 THITH_06685 2245d1a94568b8ce4921edb2b3e21fa3 157 Gene3D G3DSA:2.60.40.1820 29 156 1.0E-8 T 13-10-2018 THITH_06685 2245d1a94568b8ce4921edb2b3e21fa3 157 ProDom PD010978 LATE EMBRYOGENESIS ABUNDANT DESICCATION SIMILAR PROTECTANT PROTEINS RELATED EMBRYOGENESIS-ABUNDANT EMBRYOGENESIS-LIKE 49 116 5.0E-4 T 13-10-2018 THITH_15825 6aa191e4f1e19b342d87c260563e0fc7 420 PIRSF PIRSF000139 15 416 3.3E-80 T 13-10-2018 THITH_15825 6aa191e4f1e19b342d87c260563e0fc7 420 SUPERFAMILY SSF46548 23 108 4.34E-17 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_15825 6aa191e4f1e19b342d87c260563e0fc7 420 Pfam PF13534 4Fe-4S dicluster domain 27 94 1.4E-9 T 13-10-2018 THITH_15825 6aa191e4f1e19b342d87c260563e0fc7 420 Gene3D G3DSA:3.30.70.20 19 102 3.5E-8 T 13-10-2018 THITH_15825 6aa191e4f1e19b342d87c260563e0fc7 420 Pfam PF02754 Cysteine-rich domain 307 392 2.1E-10 T 13-10-2018 IPR004017 Cysteine-rich domain THITH_15825 6aa191e4f1e19b342d87c260563e0fc7 420 Pfam PF02754 Cysteine-rich domain 191 272 2.3E-8 T 13-10-2018 IPR004017 Cysteine-rich domain THITH_15825 6aa191e4f1e19b342d87c260563e0fc7 420 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 28 39 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_15825 6aa191e4f1e19b342d87c260563e0fc7 420 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 80 91 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 SUPERFAMILY SSF141571 112 269 1.67E-27 T 13-10-2018 THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 SMART SM00369 549 573 74.0 T 13-10-2018 IPR003591 Leucine-rich repeat, typical subtype THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 SMART SM00369 640 661 7.2 T 13-10-2018 IPR003591 Leucine-rich repeat, typical subtype THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 SMART SM00369 592 614 13.0 T 13-10-2018 IPR003591 Leucine-rich repeat, typical subtype THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 Gene3D G3DSA:3.80.10.10 478 691 2.0E-32 T 13-10-2018 IPR032675 Leucine-rich repeat domain superfamily THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 SUPERFAMILY SSF141571 226 392 1.31E-26 T 13-10-2018 THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 Gene3D G3DSA:2.160.20.100 1 86 5.8E-16 T 13-10-2018 THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 Pfam PF00805 Pentapeptide repeats (8 copies) 226 263 9.9E-10 T 13-10-2018 IPR001646 Pentapeptide repeat THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 Pfam PF00805 Pentapeptide repeats (8 copies) 40 76 3.7E-5 T 13-10-2018 IPR001646 Pentapeptide repeat THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 Pfam PF00805 Pentapeptide repeats (8 copies) 132 167 1.2E-8 T 13-10-2018 IPR001646 Pentapeptide repeat THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 Pfam PF00805 Pentapeptide repeats (8 copies) 1 31 1.2E-8 T 13-10-2018 IPR001646 Pentapeptide repeat THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 Gene3D G3DSA:2.160.20.100 275 395 2.2E-20 T 13-10-2018 THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 SUPERFAMILY SSF52058 485 658 8.08E-23 T 13-10-2018 THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 Pfam PF13599 Pentapeptide repeats (9 copies) 304 387 9.3E-9 T 13-10-2018 IPR001646 Pentapeptide repeat THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 SUPERFAMILY SSF141571 1 81 4.05E-15 T 13-10-2018 THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 Gene3D G3DSA:2.160.20.100 223 274 5.7E-10 T 13-10-2018 THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 Gene3D G3DSA:2.160.20.100 87 207 2.0E-20 T 13-10-2018 THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 PRINTS PR00019 Leucine-rich repeat signature 640 653 9.2E-5 T 13-10-2018 THITH_10550 7f66fb64e61791fde6a10a3c3cede64a 725 PRINTS PR00019 Leucine-rich repeat signature 595 608 9.2E-5 T 13-10-2018 THITH_07405 dbef83fabe5fa95d2ba9478cabb54f77 267 Gene3D G3DSA:3.40.830.10 6 267 6.0E-64 T 13-10-2018 THITH_07405 dbef83fabe5fa95d2ba9478cabb54f77 267 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 8 264 4.0E-80 T 13-10-2018 THITH_07405 dbef83fabe5fa95d2ba9478cabb54f77 267 Pfam PF01875 Memo-like protein 10 263 2.1E-51 T 13-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 THITH_07405 dbef83fabe5fa95d2ba9478cabb54f77 267 Hamap MF_00055 MEMO1 family protein . 6 267 48.946 T 13-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 THITH_03540 0bd57d9962bd43b55bfedb02cd99546e 140 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 93 3.0E-33 T 13-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03540 0bd57d9962bd43b55bfedb02cd99546e 140 Pfam PF01250 Ribosomal protein S6 3 91 9.4E-27 T 13-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03540 0bd57d9962bd43b55bfedb02cd99546e 140 SUPERFAMILY SSF54995 1 102 1.31E-35 T 13-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03540 0bd57d9962bd43b55bfedb02cd99546e 140 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 94 21.55 T 13-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 THITH_03540 0bd57d9962bd43b55bfedb02cd99546e 140 Gene3D G3DSA:3.30.70.60 1 92 3.3E-30 T 13-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 THITH_08825 2da20185897cd018fb259165e712f03d 76 Gene3D G3DSA:2.10.260.10 1 76 3.4E-36 T 13-10-2018 THITH_08825 2da20185897cd018fb259165e712f03d 76 SUPERFAMILY SSF89447 4 52 7.32E-5 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily THITH_08825 2da20185897cd018fb259165e712f03d 76 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 7 52 9.5E-7 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THITH_16570 bc128c468c6f5161e1fbd32778e7af47 482 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 81 155 4.4E-15 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_16570 bc128c468c6f5161e1fbd32778e7af47 482 SUPERFAMILY SSF46626 285 382 7.56E-22 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_16570 bc128c468c6f5161e1fbd32778e7af47 482 Pfam PF00034 Cytochrome c 405 481 4.3E-10 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_16570 bc128c468c6f5161e1fbd32778e7af47 482 Pfam PF00034 Cytochrome c 297 374 6.0E-9 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_16570 bc128c468c6f5161e1fbd32778e7af47 482 Pfam PF00034 Cytochrome c 189 266 2.3E-10 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_16570 bc128c468c6f5161e1fbd32778e7af47 482 Gene3D G3DSA:1.10.760.10 402 482 2.3E-24 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_16570 bc128c468c6f5161e1fbd32778e7af47 482 Gene3D G3DSA:1.10.760.10 186 268 9.9E-24 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_16570 bc128c468c6f5161e1fbd32778e7af47 482 Gene3D G3DSA:1.10.760.10 294 376 4.0E-23 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_16570 bc128c468c6f5161e1fbd32778e7af47 482 SUPERFAMILY SSF46626 170 274 1.89E-22 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_16570 bc128c468c6f5161e1fbd32778e7af47 482 SUPERFAMILY SSF46626 74 160 2.77E-13 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_16570 bc128c468c6f5161e1fbd32778e7af47 482 Gene3D G3DSA:1.10.760.10 80 158 1.2E-28 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_16570 bc128c468c6f5161e1fbd32778e7af47 482 SUPERFAMILY SSF46626 392 482 3.87E-21 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_16570 bc128c468c6f5161e1fbd32778e7af47 482 PRINTS PR00607 Class IE cytochrome C signature 130 142 2.0E-10 T 13-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 THITH_16570 bc128c468c6f5161e1fbd32778e7af47 482 PRINTS PR00607 Class IE cytochrome C signature 145 156 2.0E-10 T 13-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 THITH_16570 bc128c468c6f5161e1fbd32778e7af47 482 PRINTS PR00607 Class IE cytochrome C signature 90 101 2.0E-10 T 13-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 THITH_16570 bc128c468c6f5161e1fbd32778e7af47 482 PRINTS PR00607 Class IE cytochrome C signature 101 111 2.0E-10 T 13-10-2018 IPR002323 Cytochrome c, class IE GO:0005506|GO:0009055|GO:0020037 THITH_15345 69d11abf2a75e3446e1b35937ec54ddf 94 Pfam PF02954 Bacterial regulatory protein, Fis family 51 90 6.6E-15 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_15345 69d11abf2a75e3446e1b35937ec54ddf 94 PRINTS PR01591 DNA-binding protein FIS signature 22 38 3.6E-8 T 13-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 THITH_15345 69d11abf2a75e3446e1b35937ec54ddf 94 PRINTS PR01591 DNA-binding protein FIS signature 38 53 3.6E-8 T 13-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 THITH_15345 69d11abf2a75e3446e1b35937ec54ddf 94 PRINTS PR01591 DNA-binding protein FIS signature 53 65 3.6E-8 T 13-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 THITH_15345 69d11abf2a75e3446e1b35937ec54ddf 94 SUPERFAMILY SSF46689 24 93 1.61E-19 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_15345 69d11abf2a75e3446e1b35937ec54ddf 94 PIRSF PIRSF002097 4 94 4.2E-30 T 13-10-2018 IPR005412 DNA-binding protein Fis GO:0003677|GO:0006355 THITH_15345 69d11abf2a75e3446e1b35937ec54ddf 94 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 57 74 1.6E-11 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_15345 69d11abf2a75e3446e1b35937ec54ddf 94 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 74 94 1.6E-11 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_15345 69d11abf2a75e3446e1b35937ec54ddf 94 Gene3D G3DSA:1.10.10.60 9 93 1.6E-23 T 13-10-2018 THITH_07910 30f6ed9e239e5a8ce97a770e12a9e922 231 SUPERFAMILY SSF52540 8 229 1.23E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_07910 30f6ed9e239e5a8ce97a770e12a9e922 231 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_07910 30f6ed9e239e5a8ce97a770e12a9e922 231 SMART SM00382 37 225 1.8E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_07910 30f6ed9e239e5a8ce97a770e12a9e922 231 Pfam PF00005 ABC transporter 28 176 7.2E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_07910 30f6ed9e239e5a8ce97a770e12a9e922 231 Gene3D G3DSA:3.40.50.300 6 231 2.3E-62 T 13-10-2018 THITH_04490 ea4d3c91787f95b96757d44def085b7e 368 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 160 363 3.2E-25 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THITH_04490 ea4d3c91787f95b96757d44def085b7e 368 Gene3D G3DSA:1.10.3720.10 130 360 6.1E-11 T 13-10-2018 IPR035906 MetI-like superfamily THITH_04490 ea4d3c91787f95b96757d44def085b7e 368 SUPERFAMILY SSF161098 137 346 6.54E-10 T 13-10-2018 IPR035906 MetI-like superfamily THITH_04995 a664efa5a5d86221ac94032c35ba64b5 157 Gene3D G3DSA:1.20.1260.100 4 157 2.7E-51 T 13-10-2018 IPR038330 TspO/MBR-related superfamily THITH_04995 a664efa5a5d86221ac94032c35ba64b5 157 Pfam PF03073 TspO/MBR family 12 154 2.7E-44 T 13-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 THITH_04995 a664efa5a5d86221ac94032c35ba64b5 157 PIRSF PIRSF005859 3 157 1.1E-46 T 13-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 THITH_07225 a396e6c25f68ee9b260b965053846560 486 Pfam PF13749 Putative ATP-dependent DNA helicase recG C-terminal 297 362 1.9E-12 T 13-10-2018 IPR025831 ATP-dependent DNA helicase RecG, C-terminal domain THITH_07225 a396e6c25f68ee9b260b965053846560 486 Gene3D G3DSA:3.30.565.60 225 379 1.9E-27 T 13-10-2018 IPR038475 RecG, C-terminal domain superfamily THITH_07225 a396e6c25f68ee9b260b965053846560 486 Gene3D G3DSA:3.30.950.30 2 127 7.9E-19 T 13-10-2018 IPR038461 Schlafen, AAA domain superfamily THITH_07225 a396e6c25f68ee9b260b965053846560 486 Pfam PF04326 Putative DNA-binding domain 14 127 3.6E-17 T 13-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 Pfam PF01627 Hpt domain 680 754 8.8E-6 T 13-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 Gene3D G3DSA:3.40.50.2300 516 647 1.8E-32 T 13-10-2018 THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 SMART SM00388 273 338 1.5E-20 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 SUPERFAMILY SSF47384 259 339 4.12E-20 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 SMART SM00387 385 501 1.4E-39 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 Pfam PF00512 His Kinase A (phospho-acceptor) domain 273 338 1.6E-17 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 Gene3D G3DSA:3.30.565.10 337 502 7.1E-48 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 Gene3D G3DSA:1.20.120.160 666 760 8.8E-10 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 SUPERFAMILY SSF55874 327 497 2.62E-45 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 SUPERFAMILY SSF47226 624 755 7.46E-12 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 Pfam PF00072 Response regulator receiver domain 528 639 1.9E-22 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 PRINTS PR00344 Bacterial sensor protein C-terminal signature 485 498 3.6E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 PRINTS PR00344 Bacterial sensor protein C-terminal signature 461 479 3.6E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 PRINTS PR00344 Bacterial sensor protein C-terminal signature 444 454 3.6E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 440 3.6E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 SMART SM00304 188 240 2.2E-5 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 Gene3D G3DSA:1.10.287.130 236 336 3.0E-25 T 13-10-2018 THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 385 499 2.2E-26 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 SUPERFAMILY SSF158472 188 237 2.88E-5 T 13-10-2018 THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 SMART SM00448 526 639 5.1E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_17205 4969d37b56fa4db2eb416d2082a516b3 761 SUPERFAMILY SSF52172 524 646 1.85E-33 T 13-10-2018 IPR011006 CheY-like superfamily THITH_15265 fe6573f09885b15aeda99bf650782ea8 208 PRINTS PR01022 Outer membrane protein A signature 116 135 8.3E-6 T 13-10-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 THITH_15265 fe6573f09885b15aeda99bf650782ea8 208 PRINTS PR01022 Outer membrane protein A signature 155 174 8.3E-6 T 13-10-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 THITH_15265 fe6573f09885b15aeda99bf650782ea8 208 PRINTS PR01022 Outer membrane protein A signature 87 102 8.3E-6 T 13-10-2018 IPR002368 Outer membrane protein, OmpA GO:0005198|GO:0009279|GO:0016021 THITH_15265 fe6573f09885b15aeda99bf650782ea8 208 Pfam PF00691 OmpA family 98 195 2.2E-23 T 13-10-2018 IPR006665 OmpA-like domain THITH_15265 fe6573f09885b15aeda99bf650782ea8 208 PRINTS PR01021 OMPA domain signature 131 146 1.7E-18 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THITH_15265 fe6573f09885b15aeda99bf650782ea8 208 PRINTS PR01021 OMPA domain signature 146 162 1.7E-18 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THITH_15265 fe6573f09885b15aeda99bf650782ea8 208 PRINTS PR01021 OMPA domain signature 99 121 1.7E-18 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THITH_15265 fe6573f09885b15aeda99bf650782ea8 208 Gene3D G3DSA:3.30.1330.60 76 208 3.4E-42 T 13-10-2018 IPR036737 OmpA-like domain superfamily THITH_15265 fe6573f09885b15aeda99bf650782ea8 208 SUPERFAMILY SSF103088 71 200 1.57E-37 T 13-10-2018 IPR036737 OmpA-like domain superfamily THITH_13555 b798ef4b11623e4b1e3d40e42c0d9edc 89 Gene3D G3DSA:3.30.370.10 1 80 1.3E-5 T 13-10-2018 IPR035905 Barstar-like superfamily THITH_13555 b798ef4b11623e4b1e3d40e42c0d9edc 89 Pfam PF01337 Barstar (barnase inhibitor) 2 74 3.6E-16 T 13-10-2018 IPR000468 Barstar (barnase inhibitor) THITH_13555 b798ef4b11623e4b1e3d40e42c0d9edc 89 SUPERFAMILY SSF52038 3 73 6.41E-14 T 13-10-2018 IPR035905 Barstar-like superfamily THITH_06170 62fa5fc10f1b71831acadc00b569f395 426 Pfam PF01566 Natural resistance-associated macrophage protein 32 390 5.0E-12 T 13-10-2018 IPR001046 NRAMP family GO:0016020|GO:0030001|GO:0046873 Reactome: R-HSA-425410 THITH_08470 59298af0f0e901595aefe83c41c914ce 494 SUPERFAMILY SSF52540 232 474 6.23E-38 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_08470 59298af0f0e901595aefe83c41c914ce 494 SMART SM00382 260 394 5.3E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_08470 59298af0f0e901595aefe83c41c914ce 494 Gene3D G3DSA:3.40.50.300 227 392 3.5E-38 T 13-10-2018 THITH_08470 59298af0f0e901595aefe83c41c914ce 494 Gene3D G3DSA:1.10.8.60 393 450 3.5E-38 T 13-10-2018 THITH_08470 59298af0f0e901595aefe83c41c914ce 494 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 264 391 8.8E-19 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THITH_08470 59298af0f0e901595aefe83c41c914ce 494 SUPERFAMILY SSF52540 66 195 1.87E-7 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13375 fb69478d69427dc85ccff3cdf3ee3679 126 Pfam PF01850 PIN domain 3 116 1.5E-6 T 13-10-2018 IPR002716 PIN domain THITH_13375 fb69478d69427dc85ccff3cdf3ee3679 126 Gene3D G3DSA:3.40.50.1010 3 121 1.6E-19 T 13-10-2018 THITH_13375 fb69478d69427dc85ccff3cdf3ee3679 126 SUPERFAMILY SSF88723 3 121 5.89E-13 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_13140 47110ee378c9e889dacf8810be1dd9ff 292 Gene3D G3DSA:3.40.50.10330 24 288 5.5E-88 T 13-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 THITH_13140 47110ee378c9e889dacf8810be1dd9ff 292 SUPERFAMILY SSF111331 7 290 4.58E-81 T 13-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily THITH_13140 47110ee378c9e889dacf8810be1dd9ff 292 Pfam PF01513 ATP-NAD kinase 59 271 1.5E-58 T 13-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 THITH_13140 47110ee378c9e889dacf8810be1dd9ff 292 Gene3D G3DSA:2.60.200.30 128 265 5.5E-88 T 13-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 THITH_13140 47110ee378c9e889dacf8810be1dd9ff 292 Hamap MF_00361 NAD kinase [nadK]. 6 288 32.951 T 13-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 THITH_04060 ba2321f281126f9e1309a32af06da310 228 SUPERFAMILY SSF52172 4 128 6.97E-37 T 13-10-2018 IPR011006 CheY-like superfamily THITH_04060 ba2321f281126f9e1309a32af06da310 228 SUPERFAMILY SSF46894 145 214 2.14E-22 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THITH_04060 ba2321f281126f9e1309a32af06da310 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.3E-13 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_04060 ba2321f281126f9e1309a32af06da310 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.3E-13 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_04060 ba2321f281126f9e1309a32af06da310 228 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.3E-13 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_04060 ba2321f281126f9e1309a32af06da310 228 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 1.8E-21 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_04060 ba2321f281126f9e1309a32af06da310 228 Pfam PF00072 Response regulator receiver domain 5 115 4.9E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_04060 ba2321f281126f9e1309a32af06da310 228 Gene3D G3DSA:3.40.50.12740 4 214 1.2E-68 T 13-10-2018 THITH_04060 ba2321f281126f9e1309a32af06da310 228 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_04060 ba2321f281126f9e1309a32af06da310 228 SMART SM00448 3 115 4.8E-40 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_04060 ba2321f281126f9e1309a32af06da310 228 SMART SM00421 152 209 1.6E-24 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_14200 b45f1de8ea8947e5a2cb6f223123e743 59 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 17.486 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14200 b45f1de8ea8947e5a2cb6f223123e743 59 SUPERFAMILY SSF55129 1 59 3.27E-17 T 13-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily THITH_14200 b45f1de8ea8947e5a2cb6f223123e743 59 Pfam PF00327 Ribosomal protein L30p/L7e 4 53 5.5E-13 T 13-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain THITH_14200 b45f1de8ea8947e5a2cb6f223123e743 59 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 1.1E-16 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14200 b45f1de8ea8947e5a2cb6f223123e743 59 PIRSF PIRSF002211 1 59 2.0E-22 T 13-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14200 b45f1de8ea8947e5a2cb6f223123e743 59 Gene3D G3DSA:3.30.1390.20 1 59 2.0E-21 T 13-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily THITH_02700 7f86f79ee94756f96baf3fffb2965777 280 Gene3D G3DSA:1.10.760.10 156 280 5.1E-28 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_02700 7f86f79ee94756f96baf3fffb2965777 280 Gene3D G3DSA:1.10.760.10 59 155 4.2E-25 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_02700 7f86f79ee94756f96baf3fffb2965777 280 SUPERFAMILY SSF46626 47 160 5.92E-18 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_02700 7f86f79ee94756f96baf3fffb2965777 280 SUPERFAMILY SSF46626 166 273 1.75E-21 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_02700 7f86f79ee94756f96baf3fffb2965777 280 TIGRFAM TIGR04484 thiosulf_SoxA: sulfur oxidation c-type cytochrome SoxA 57 280 3.1E-58 T 13-10-2018 IPR025710 SoxAX cytochrome complex subunit A GO:0009055|GO:0016491|GO:0019417|GO:0020037|GO:0070069 THITH_11400 911d759ba13ef182f279c4fe5868c936 452 Gene3D G3DSA:3.40.640.10 79 352 5.3E-144 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_11400 911d759ba13ef182f279c4fe5868c936 452 SUPERFAMILY SSF53383 1 449 1.73E-113 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_11400 911d759ba13ef182f279c4fe5868c936 452 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 1 449 46.027 T 13-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 THITH_11400 911d759ba13ef182f279c4fe5868c936 452 Gene3D G3DSA:3.90.1150.10 68 446 5.3E-144 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_11400 911d759ba13ef182f279c4fe5868c936 452 PIRSF PIRSF006815 1 450 6.3E-159 T 13-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 THITH_11400 911d759ba13ef182f279c4fe5868c936 452 Pfam PF02347 Glycine cleavage system P-protein 3 444 4.5E-120 T 13-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 THITH_17475 72955a2e6d7d2f0d50f24c545f7964a8 148 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 19 43 1.7E-10 T 13-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_17475 72955a2e6d7d2f0d50f24c545f7964a8 148 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 123 146 1.7E-10 T 13-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_17475 72955a2e6d7d2f0d50f24c545f7964a8 148 PRINTS PR00122 Vacuolar ATP synthase 16kDa subunit signature 96 122 1.7E-10 T 13-10-2018 IPR000245 V-ATPase proteolipid subunit GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_17475 72955a2e6d7d2f0d50f24c545f7964a8 148 Gene3D G3DSA:1.20.120.610 2 148 1.5E-14 T 13-10-2018 THITH_17475 72955a2e6d7d2f0d50f24c545f7964a8 148 SUPERFAMILY SSF81333 80 146 1.03E-14 T 13-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily THITH_17475 72955a2e6d7d2f0d50f24c545f7964a8 148 Pfam PF00137 ATP synthase subunit C 85 144 7.0E-16 T 13-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 THITH_10725 95286a3c2b40865c5063558f07830509 160 Pfam PF03734 L,D-transpeptidase catalytic domain 2 155 5.7E-20 T 13-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 THITH_10725 95286a3c2b40865c5063558f07830509 160 SUPERFAMILY SSF141523 2 156 7.46E-26 T 13-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like THITH_10725 95286a3c2b40865c5063558f07830509 160 Gene3D G3DSA:2.40.440.10 1 159 1.3E-29 T 13-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like THITH_03815 0e394848a46f05fcef40861633155281 495 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 3 494 37.294 T 13-10-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 THITH_03815 0e394848a46f05fcef40861633155281 495 SUPERFAMILY SSF52949 1 180 1.77E-33 T 13-10-2018 THITH_03815 0e394848a46f05fcef40861633155281 495 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 184 485 5.0E-129 T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 THITH_03815 0e394848a46f05fcef40861633155281 495 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 346 353 - T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 THITH_03815 0e394848a46f05fcef40861633155281 495 PRINTS PR00481 Cytosol aminopeptidase signature 261 278 6.7E-53 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THITH_03815 0e394848a46f05fcef40861633155281 495 PRINTS PR00481 Cytosol aminopeptidase signature 342 362 6.7E-53 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THITH_03815 0e394848a46f05fcef40861633155281 495 PRINTS PR00481 Cytosol aminopeptidase signature 283 304 6.7E-53 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THITH_03815 0e394848a46f05fcef40861633155281 495 PRINTS PR00481 Cytosol aminopeptidase signature 320 341 6.7E-53 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THITH_03815 0e394848a46f05fcef40861633155281 495 PRINTS PR00481 Cytosol aminopeptidase signature 370 385 6.7E-53 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THITH_03815 0e394848a46f05fcef40861633155281 495 Gene3D G3DSA:3.40.220.10 1 178 8.1E-36 T 13-10-2018 THITH_03815 0e394848a46f05fcef40861633155281 495 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 19 145 2.0E-23 T 13-10-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 THITH_03815 0e394848a46f05fcef40861633155281 495 Gene3D G3DSA:3.40.630.10 179 494 6.3E-141 T 13-10-2018 THITH_03815 0e394848a46f05fcef40861633155281 495 SUPERFAMILY SSF53187 178 491 4.5E-125 T 13-10-2018 THITH_12245 ef00169234afac2d7f8ad00d97e31085 349 Gene3D G3DSA:3.30.2350.20 18 333 1.6E-104 T 13-10-2018 THITH_12245 ef00169234afac2d7f8ad00d97e31085 349 SUPERFAMILY SSF55120 16 332 1.04E-81 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_12245 ef00169234afac2d7f8ad00d97e31085 349 Gene3D G3DSA:3.30.2340.10 169 300 1.6E-104 T 13-10-2018 THITH_12245 ef00169234afac2d7f8ad00d97e31085 349 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 6 341 24.018 T 13-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_12245 ef00169234afac2d7f8ad00d97e31085 349 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 17 170 4.9E-40 T 13-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_12245 ef00169234afac2d7f8ad00d97e31085 349 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 187 333 3.1E-11 T 13-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_12245 ef00169234afac2d7f8ad00d97e31085 349 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 78 91 - T 13-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 THITH_08275 6f9db5bcfd72b1ce34d20407efc2c1cc 533 Gene3D G3DSA:3.40.50.1820 77 337 7.6E-16 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_08275 6f9db5bcfd72b1ce34d20407efc2c1cc 533 SUPERFAMILY SSF53474 87 246 1.74E-13 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_08545 045caa723f3cd5914fb424d0322b652e 81 Gene3D G3DSA:3.90.1570.10 7 79 4.8E-8 T 13-10-2018 THITH_08545 045caa723f3cd5914fb424d0322b652e 81 Pfam PF05685 Putative restriction endonuclease 10 69 1.6E-10 T 13-10-2018 IPR008538 Domain of unknown function DUF820 THITH_08545 045caa723f3cd5914fb424d0322b652e 81 SUPERFAMILY SSF52980 8 79 4.93E-12 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_10160 df8d0b904dcc71cbe710b1758b7da9aa 719 Gene3D G3DSA:3.30.1370.120 185 243 1.9E-6 T 13-10-2018 IPR038591 NolW-like superfamily THITH_10160 df8d0b904dcc71cbe710b1758b7da9aa 719 TIGRFAM TIGR02517 type_II_gspD: type II secretion system protein D 89 686 6.5E-123 T 13-10-2018 IPR013356 Type II secretion system GspD GO:0008565|GO:0015627|GO:0015628|GO:0019867 THITH_10160 df8d0b904dcc71cbe710b1758b7da9aa 719 Pfam PF00263 Bacterial type II and III secretion system protein 515 677 4.8E-45 T 13-10-2018 IPR004846 Type II/III secretion system GO:0009306 THITH_10160 df8d0b904dcc71cbe710b1758b7da9aa 719 Gene3D G3DSA:3.30.1370.120 249 320 1.7E-7 T 13-10-2018 IPR038591 NolW-like superfamily THITH_10160 df8d0b904dcc71cbe710b1758b7da9aa 719 Gene3D G3DSA:3.55.50.30 82 174 4.4E-14 T 13-10-2018 THITH_10160 df8d0b904dcc71cbe710b1758b7da9aa 719 Pfam PF03958 Bacterial type II/III secretion system short domain 330 446 4.0E-14 T 13-10-2018 IPR005644 NolW-like THITH_10160 df8d0b904dcc71cbe710b1758b7da9aa 719 Pfam PF03958 Bacterial type II/III secretion system short domain 250 318 1.4E-7 T 13-10-2018 IPR005644 NolW-like THITH_10160 df8d0b904dcc71cbe710b1758b7da9aa 719 PRINTS PR00811 Bacterial general secretion pathway protein D signature 446 456 2.7E-15 T 13-10-2018 IPR001775 GspD/PilQ family THITH_10160 df8d0b904dcc71cbe710b1758b7da9aa 719 PRINTS PR00811 Bacterial general secretion pathway protein D signature 664 678 2.7E-15 T 13-10-2018 IPR001775 GspD/PilQ family THITH_10160 df8d0b904dcc71cbe710b1758b7da9aa 719 PRINTS PR00811 Bacterial general secretion pathway protein D signature 511 535 2.7E-15 T 13-10-2018 IPR001775 GspD/PilQ family THITH_10160 df8d0b904dcc71cbe710b1758b7da9aa 719 PRINTS PR00811 Bacterial general secretion pathway protein D signature 641 659 2.7E-15 T 13-10-2018 IPR001775 GspD/PilQ family THITH_00985 8e1fd43e1d6a694db2819471178da56e 174 Gene3D G3DSA:2.60.40.1890 44 160 7.2E-38 T 13-10-2018 IPR036182 Copper chaperone PCuAC superfamily THITH_00985 8e1fd43e1d6a694db2819471178da56e 174 SUPERFAMILY SSF110087 40 159 3.14E-42 T 13-10-2018 IPR036182 Copper chaperone PCuAC superfamily THITH_00985 8e1fd43e1d6a694db2819471178da56e 174 Pfam PF04314 Copper chaperone PCu(A)C 42 146 2.8E-38 T 13-10-2018 IPR007410 Copper chaperone PCuAC THITH_09280 fd1a4c1e9e8cba95e5467d4e22d5a983 135 SUPERFAMILY SSF158568 4 122 2.35E-27 T 13-10-2018 IPR023101 AF1862-like domain superfamily THITH_09280 fd1a4c1e9e8cba95e5467d4e22d5a983 135 Gene3D G3DSA:1.10.520.30 2 122 3.9E-29 T 13-10-2018 IPR023101 AF1862-like domain superfamily THITH_09280 fd1a4c1e9e8cba95e5467d4e22d5a983 135 Pfam PF09701 CRISPR-associated protein (Cas_Cmr5) 5 119 4.2E-29 T 13-10-2018 IPR010160 CRISPR-associated protein, Cmr5 THITH_09280 fd1a4c1e9e8cba95e5467d4e22d5a983 135 TIGRFAM TIGR01881 cas_Cmr5: CRISPR type III-B/RAMP module-associated protein Cmr5 8 121 1.3E-13 T 13-10-2018 IPR010160 CRISPR-associated protein, Cmr5 THITH_04055 369d80551284452d1e34c09adf32fd62 113 Gene3D G3DSA:2.10.109.10 5 106 2.1E-21 T 13-10-2018 THITH_04055 369d80551284452d1e34c09adf32fd62 113 Pfam PF00717 Peptidase S24-like 24 90 2.7E-14 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C THITH_04055 369d80551284452d1e34c09adf32fd62 113 SUPERFAMILY SSF51306 17 100 8.72E-21 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily THITH_06545 e4dc5378477c5e574ad270b40c60c03f 204 SUPERFAMILY SSF141523 43 203 2.62E-18 T 13-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like THITH_06545 e4dc5378477c5e574ad270b40c60c03f 204 Pfam PF03734 L,D-transpeptidase catalytic domain 48 203 1.0E-19 T 13-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 THITH_06545 e4dc5378477c5e574ad270b40c60c03f 204 Gene3D G3DSA:2.40.440.10 22 204 3.1E-18 T 13-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like THITH_09705 5eda42fa7f938b2301fd4a14773cbdc9 315 SUPERFAMILY SSF52096 138 298 6.71E-14 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THITH_09705 5eda42fa7f938b2301fd4a14773cbdc9 315 Gene3D G3DSA:3.90.226.10 135 299 7.6E-11 T 13-10-2018 THITH_03830 ee5d9b88fae70629159d3eba2b01314c 755 Gene3D G3DSA:1.20.5.1050 470 592 2.0E-5 T 13-10-2018 THITH_03830 ee5d9b88fae70629159d3eba2b01314c 755 Gene3D G3DSA:3.10.350.10 703 753 3.5E-7 T 13-10-2018 IPR036779 LysM domain superfamily THITH_03830 ee5d9b88fae70629159d3eba2b01314c 755 SMART SM00257 703 755 0.0048 T 13-10-2018 IPR018392 LysM domain THITH_03830 ee5d9b88fae70629159d3eba2b01314c 755 Pfam PF01476 LysM domain 704 755 1.3E-4 T 13-10-2018 IPR018392 LysM domain THITH_03830 ee5d9b88fae70629159d3eba2b01314c 755 SUPERFAMILY SSF90257 475 588 1.07E-5 T 13-10-2018 THITH_05095 5e132b5f39ac3ae5a99c8136bba02776 910 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 190 722 2.7E-77 T 13-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit THITH_05095 5e132b5f39ac3ae5a99c8136bba02776 910 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 124 779 1.2E-193 T 13-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ THITH_05095 5e132b5f39ac3ae5a99c8136bba02776 910 Pfam PF11874 Domain of unknown function (DUF3394) 729 906 5.9E-61 T 13-10-2018 IPR021814 Protein of unknown function DUF3394 THITH_05550 9b7ccdf14e8e3f33481ef1b397bc5de9 787 Pfam PF13807 G-rich domain on putative tyrosine kinase 425 495 5.4E-15 T 13-10-2018 IPR032807 Tyrosine kinase, G-rich domain THITH_05550 9b7ccdf14e8e3f33481ef1b397bc5de9 787 Pfam PF02706 Chain length determinant protein 40 133 5.4E-10 T 13-10-2018 IPR003856 Polysaccharide chain length determinant N-terminal domain GO:0009103|GO:0016020 THITH_05550 9b7ccdf14e8e3f33481ef1b397bc5de9 787 TIGRFAM TIGR01007 eps_fam: capsular exopolysaccharide family 558 765 1.6E-50 T 13-10-2018 IPR005702 Exopolysaccharide synthesis protein GO:0045226 THITH_05550 9b7ccdf14e8e3f33481ef1b397bc5de9 787 SUPERFAMILY SSF52540 575 764 3.63E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_05550 9b7ccdf14e8e3f33481ef1b397bc5de9 787 Gene3D G3DSA:3.40.50.300 492 774 4.6E-81 T 13-10-2018 THITH_05550 9b7ccdf14e8e3f33481ef1b397bc5de9 787 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 580 754 7.1E-12 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THITH_16445 035931d54257cdca1114624b1c5a5c72 447 Pfam PF00675 Insulinase (Peptidase family M16) 38 183 5.4E-27 T 13-10-2018 IPR011765 Peptidase M16, N-terminal THITH_16445 035931d54257cdca1114624b1c5a5c72 447 SUPERFAMILY SSF63411 26 240 2.0E-64 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THITH_16445 035931d54257cdca1114624b1c5a5c72 447 Pfam PF05193 Peptidase M16 inactive domain 193 372 4.2E-26 T 13-10-2018 IPR007863 Peptidase M16, C-terminal THITH_16445 035931d54257cdca1114624b1c5a5c72 447 Gene3D G3DSA:3.30.830.10 22 244 5.7E-82 T 13-10-2018 THITH_16445 035931d54257cdca1114624b1c5a5c72 447 Gene3D G3DSA:3.30.830.10 246 440 8.8E-56 T 13-10-2018 THITH_16445 035931d54257cdca1114624b1c5a5c72 447 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 58 81 - T 13-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 THITH_16445 035931d54257cdca1114624b1c5a5c72 447 SUPERFAMILY SSF63411 244 441 1.47E-36 T 13-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 THITH_08410 09044adc20c424ed2636e48caaccfccb 448 SUPERFAMILY SSF81442 3 436 7.85E-86 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_08410 09044adc20c424ed2636e48caaccfccb 448 Gene3D G3DSA:1.20.210.10 1 444 1.8E-123 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_08410 09044adc20c424ed2636e48caaccfccb 448 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 7 415 3.1E-75 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_07430 8b0f2b3357bb5a000c9a76473edd5804 273 Pfam PF00925 GTP cyclohydrolase II 103 238 1.6E-42 T 13-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 THITH_07430 8b0f2b3357bb5a000c9a76473edd5804 273 SUPERFAMILY SSF142695 102 236 6.41E-38 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 THITH_07430 8b0f2b3357bb5a000c9a76473edd5804 273 Gene3D G3DSA:3.40.50.10990 68 244 1.2E-50 T 13-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 THITH_00055 92c8b118081a9153b4d4fca8c0d263ff 227 Pfam PF01370 NAD dependent epimerase/dehydratase family 25 97 6.5E-7 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 THITH_00055 92c8b118081a9153b4d4fca8c0d263ff 227 Gene3D G3DSA:3.40.50.720 1 223 1.8E-53 T 13-10-2018 THITH_00055 92c8b118081a9153b4d4fca8c0d263ff 227 SUPERFAMILY SSF51735 28 210 1.71E-28 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_14385 dcab3e42f5fb7408d202d1a0af641926 570 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 54 144 1.3E-15 T 13-10-2018 IPR007831 General secretory system II, protein E, N-terminal THITH_14385 dcab3e42f5fb7408d202d1a0af641926 570 Pfam PF00437 Type II/IV secretion system protein 193 460 2.2E-90 T 13-10-2018 IPR001482 Type II/IV secretion system protein THITH_14385 dcab3e42f5fb7408d202d1a0af641926 570 TIGRFAM TIGR02538 type_IV_pilB: type IV-A pilus assembly ATPase PilB 12 570 2.0E-252 T 13-10-2018 IPR013374 ATPase, type IV, pilus assembly, PilB GO:0005524|GO:0008565|GO:0009297 THITH_14385 dcab3e42f5fb7408d202d1a0af641926 570 SUPERFAMILY SSF52540 179 568 2.4E-97 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14385 dcab3e42f5fb7408d202d1a0af641926 570 Gene3D G3DSA:3.40.50.300 294 570 6.2E-105 T 13-10-2018 THITH_14385 dcab3e42f5fb7408d202d1a0af641926 570 SUPERFAMILY SSF160246 8 144 3.4E-31 T 13-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily THITH_14385 dcab3e42f5fb7408d202d1a0af641926 570 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 388 402 - T 13-10-2018 IPR001482 Type II/IV secretion system protein THITH_14385 dcab3e42f5fb7408d202d1a0af641926 570 Gene3D G3DSA:3.30.300.160 67 146 5.0E-8 T 13-10-2018 THITH_14385 dcab3e42f5fb7408d202d1a0af641926 570 Gene3D G3DSA:3.30.450.90 155 293 4.3E-50 T 13-10-2018 THITH_13100 a9c1be065bbc058bf5deacf910ca7972 187 Gene3D G3DSA:2.30.30.30 1 65 1.6E-26 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 THITH_13100 a9c1be065bbc058bf5deacf910ca7972 187 PIRSF PIRSF005901 2 187 4.8E-69 T 13-10-2018 IPR020599 Translation elongation factor P/YeiP THITH_13100 a9c1be065bbc058bf5deacf910ca7972 187 SMART SM00841 131 186 7.9E-35 T 13-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 THITH_13100 a9c1be065bbc058bf5deacf910ca7972 187 SUPERFAMILY SSF50249 69 128 3.73E-17 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_13100 a9c1be065bbc058bf5deacf910ca7972 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 71 123 3.4E-23 T 13-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 THITH_13100 a9c1be065bbc058bf5deacf910ca7972 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 5 62 6.3E-25 T 13-10-2018 IPR013185 Translation elongation factor, KOW-like THITH_13100 a9c1be065bbc058bf5deacf910ca7972 187 Pfam PF09285 Elongation factor P, C-terminal 131 186 2.3E-27 T 13-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 THITH_13100 a9c1be065bbc058bf5deacf910ca7972 187 ProSitePatterns PS01275 Elongation factor P signature. 152 171 - T 13-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site THITH_13100 a9c1be065bbc058bf5deacf910ca7972 187 Hamap MF_00141 Elongation factor P [efp]. 3 187 49.632 T 13-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 THITH_13100 a9c1be065bbc058bf5deacf910ca7972 187 Gene3D G3DSA:2.40.50.140 130 187 1.9E-29 T 13-10-2018 THITH_13100 a9c1be065bbc058bf5deacf910ca7972 187 Gene3D G3DSA:2.40.50.140 66 127 1.9E-29 T 13-10-2018 THITH_13100 a9c1be065bbc058bf5deacf910ca7972 187 SMART SM01185 69 123 2.3E-27 T 13-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 THITH_13100 a9c1be065bbc058bf5deacf910ca7972 187 SUPERFAMILY SSF50104 2 63 1.65E-19 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily THITH_13100 a9c1be065bbc058bf5deacf910ca7972 187 TIGRFAM TIGR00038 efp: translation elongation factor P 4 187 2.5E-79 T 13-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 THITH_13100 a9c1be065bbc058bf5deacf910ca7972 187 SUPERFAMILY SSF50249 130 187 5.82E-19 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_07735 2c7194fa61467352c9ee937e67adf9f7 88 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 88 2.8E-12 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THITH_07735 2c7194fa61467352c9ee937e67adf9f7 88 Gene3D G3DSA:3.30.2310.20 1 88 1.5E-21 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_14720 ca882ac16a27e1c471c9c8e3684d6c1c 459 SUPERFAMILY SSF51984 4 90 1.02E-17 T 13-10-2018 THITH_14720 ca882ac16a27e1c471c9c8e3684d6c1c 459 Hamap MF_02020 UDP-N-acetylmuramate--L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptandioate ligase [mpl]. 3 452 54.859 T 13-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 THITH_14720 ca882ac16a27e1c471c9c8e3684d6c1c 459 SUPERFAMILY SSF53623 95 311 4.97E-51 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THITH_14720 ca882ac16a27e1c471c9c8e3684d6c1c 459 Pfam PF02875 Mur ligase family, glutamate ligase domain 314 362 5.5E-6 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 THITH_14720 ca882ac16a27e1c471c9c8e3684d6c1c 459 TIGRFAM TIGR01081 mpl: UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase 5 452 7.2E-184 T 13-10-2018 IPR005757 Murein peptide ligase GO:0009252|GO:0016881|GO:0071555 MetaCyc: PWY-7883 THITH_14720 ca882ac16a27e1c471c9c8e3684d6c1c 459 Pfam PF01225 Mur ligase family, catalytic domain 5 99 3.5E-12 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 THITH_14720 ca882ac16a27e1c471c9c8e3684d6c1c 459 SUPERFAMILY SSF53244 313 451 7.48E-33 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THITH_14720 ca882ac16a27e1c471c9c8e3684d6c1c 459 Pfam PF08245 Mur ligase middle domain 109 294 2.9E-20 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 THITH_14720 ca882ac16a27e1c471c9c8e3684d6c1c 459 Gene3D G3DSA:3.90.190.20 317 453 1.8E-23 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THITH_14720 ca882ac16a27e1c471c9c8e3684d6c1c 459 Gene3D G3DSA:3.40.50.720 2 91 2.9E-25 T 13-10-2018 THITH_14720 ca882ac16a27e1c471c9c8e3684d6c1c 459 Gene3D G3DSA:3.40.1190.10 94 314 9.7E-58 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THITH_01915 551a76f93316b392c0d2063d80c21ac8 189 Pfam PF01420 Type I restriction modification DNA specificity domain 2 154 1.1E-6 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THITH_01915 551a76f93316b392c0d2063d80c21ac8 189 Gene3D G3DSA:3.90.220.20 1 183 9.9E-23 T 13-10-2018 THITH_01915 551a76f93316b392c0d2063d80c21ac8 189 SUPERFAMILY SSF116734 2 175 8.34E-21 T 13-10-2018 THITH_16130 ab4f1fe8b4e41687f53559727e73840c 357 Gene3D G3DSA:2.40.50.100 70 198 3.4E-72 T 13-10-2018 THITH_16130 ab4f1fe8b4e41687f53559727e73840c 357 Gene3D G3DSA:1.10.287.470 105 164 3.4E-72 T 13-10-2018 THITH_16130 ab4f1fe8b4e41687f53559727e73840c 357 SUPERFAMILY SSF111369 60 276 1.18E-36 T 13-10-2018 THITH_16130 ab4f1fe8b4e41687f53559727e73840c 357 Gene3D G3DSA:2.40.420.20 281 349 3.4E-72 T 13-10-2018 THITH_16130 ab4f1fe8b4e41687f53559727e73840c 357 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 60 270 7.3E-30 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THITH_16130 ab4f1fe8b4e41687f53559727e73840c 357 Gene3D G3DSA:2.40.30.170 60 280 3.4E-72 T 13-10-2018 THITH_16130 ab4f1fe8b4e41687f53559727e73840c 357 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 46 351 1.3E-71 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THITH_01455 720dcc1e35eac81cd8e124e43d1ee21d 404 Pfam PF04055 Radical SAM superfamily 31 194 2.9E-18 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THITH_01455 720dcc1e35eac81cd8e124e43d1ee21d 404 Gene3D G3DSA:3.80.30.20 15 318 1.8E-96 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe THITH_01455 720dcc1e35eac81cd8e124e43d1ee21d 404 Pfam PF06969 HemN C-terminal domain 325 386 7.7E-12 T 13-10-2018 IPR010723 HemN, C-terminal THITH_01455 720dcc1e35eac81cd8e124e43d1ee21d 404 SUPERFAMILY SSF102114 23 397 3.01E-106 T 13-10-2018 THITH_01455 720dcc1e35eac81cd8e124e43d1ee21d 404 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 28 369 3.6E-111 T 13-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 THITH_01455 720dcc1e35eac81cd8e124e43d1ee21d 404 SMART SM00729 26 243 4.2E-51 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THITH_16290 ca8922914211545fb673f16fa635381c 515 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 375 395 - T 13-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site THITH_16290 ca8922914211545fb673f16fa635381c 515 Gene3D G3DSA:3.40.630.30 7 227 1.1E-56 T 13-10-2018 THITH_16290 ca8922914211545fb673f16fa635381c 515 Pfam PF00795 Carbon-nitrogen hydrolase 230 491 6.5E-34 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 THITH_16290 ca8922914211545fb673f16fa635381c 515 SUPERFAMILY SSF56317 229 512 3.01E-56 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily THITH_16290 ca8922914211545fb673f16fa635381c 515 Pfam PF00583 Acetyltransferase (GNAT) family 26 144 9.5E-8 T 13-10-2018 IPR000182 GNAT domain THITH_16290 ca8922914211545fb673f16fa635381c 515 Gene3D G3DSA:3.60.110.10 228 513 5.3E-56 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily THITH_16290 ca8922914211545fb673f16fa635381c 515 SUPERFAMILY SSF55729 16 144 2.19E-18 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_06300 44e019b22501ef67e065dcf7e0b453af 178 SUPERFAMILY SSF50324 3 175 2.75E-64 T 13-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THITH_06300 44e019b22501ef67e065dcf7e0b453af 178 Gene3D G3DSA:3.90.80.10 1 175 1.1E-66 T 13-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THITH_06300 44e019b22501ef67e065dcf7e0b453af 178 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 66 72 - T 13-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THITH_06300 44e019b22501ef67e065dcf7e0b453af 178 Pfam PF00719 Inorganic pyrophosphatase 18 174 7.7E-53 T 13-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THITH_06300 44e019b22501ef67e065dcf7e0b453af 178 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 14 174 36.749 T 13-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 THITH_16115 179716c323976b78e252e6b99d74d8ed 738 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 479 669 7.4E-18 T 13-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 THITH_16115 179716c323976b78e252e6b99d74d8ed 738 TIGRFAM TIGR02472 sucr_P_syn_N: sucrose-phosphate synthase, putative, glycosyltransferase domain 14 446 1.8E-200 T 13-10-2018 IPR012822 Sucrose-phosphate synthase, glycosyltransferase domain THITH_16115 179716c323976b78e252e6b99d74d8ed 738 Gene3D G3DSA:3.40.50.2000 36 444 5.2E-138 T 13-10-2018 THITH_16115 179716c323976b78e252e6b99d74d8ed 738 Pfam PF00534 Glycosyl transferases group 1 256 431 1.8E-22 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 THITH_16115 179716c323976b78e252e6b99d74d8ed 738 Pfam PF13439 Glycosyltransferase Family 4 39 235 7.9E-17 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 THITH_16115 179716c323976b78e252e6b99d74d8ed 738 Gene3D G3DSA:3.40.50.2000 231 439 5.2E-138 T 13-10-2018 THITH_16115 179716c323976b78e252e6b99d74d8ed 738 SUPERFAMILY SSF53756 31 453 7.85E-64 T 13-10-2018 THITH_16115 179716c323976b78e252e6b99d74d8ed 738 Pfam PF05116 Sucrose-6F-phosphate phosphohydrolase 477 713 5.0E-83 T 13-10-2018 IPR006380 Sucrose-phosphatase-like, N-terminal THITH_16115 179716c323976b78e252e6b99d74d8ed 738 SUPERFAMILY SSF56784 477 711 2.85E-31 T 13-10-2018 IPR036412 HAD-like superfamily THITH_16115 179716c323976b78e252e6b99d74d8ed 738 Gene3D G3DSA:3.40.50.1000 480 710 1.0E-75 T 13-10-2018 IPR023214 HAD superfamily THITH_16115 179716c323976b78e252e6b99d74d8ed 738 TIGRFAM TIGR02471 sucr_syn_bact_C: sucrose-phosphate synthase, sucrose phosphatase-like domain 479 712 1.8E-93 T 13-10-2018 IPR012821 Sucrose phosphate synthase, sucrose phosphatase-like domain THITH_16115 179716c323976b78e252e6b99d74d8ed 738 Gene3D G3DSA:3.90.1070.10 564 633 1.0E-75 T 13-10-2018 THITH_02640 158caab8bdcda9a99e15da1c280bc211 448 Pfam PF02754 Cysteine-rich domain 211 296 1.1E-9 T 13-10-2018 IPR004017 Cysteine-rich domain THITH_02640 158caab8bdcda9a99e15da1c280bc211 448 Pfam PF02754 Cysteine-rich domain 343 419 0.077 T 13-10-2018 IPR004017 Cysteine-rich domain THITH_02640 158caab8bdcda9a99e15da1c280bc211 448 SUPERFAMILY SSF54862 41 101 7.74E-5 T 13-10-2018 THITH_14220 0b90fe208940b9e4755fb1d41f048160 129 ProSitePatterns PS00053 Ribosomal protein S8 signature. 99 116 - T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14220 0b90fe208940b9e4755fb1d41f048160 129 SUPERFAMILY SSF56047 1 129 2.09E-43 T 13-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14220 0b90fe208940b9e4755fb1d41f048160 129 Gene3D G3DSA:3.30.1490.10 72 129 9.7E-23 T 13-10-2018 THITH_14220 0b90fe208940b9e4755fb1d41f048160 129 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 1 129 28.002 T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14220 0b90fe208940b9e4755fb1d41f048160 129 Gene3D G3DSA:3.30.1370.30 1 71 6.6E-26 T 13-10-2018 THITH_14220 0b90fe208940b9e4755fb1d41f048160 129 Pfam PF00410 Ribosomal protein S8 3 129 3.9E-46 T 13-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_08075 e3241ba15c1c20e6c871e22b1a2f472b 521 Pfam PF13598 Domain of unknown function (DUF4139) 204 508 1.1E-53 T 13-10-2018 IPR037291 Domain of unknown function DUF4139 THITH_08075 e3241ba15c1c20e6c871e22b1a2f472b 521 TIGRFAM TIGR02231 TIGR02231: conserved hypothetical protein 17 510 2.4E-94 T 13-10-2018 IPR011935 Conserved hypothetical protein CHP02231 THITH_08075 e3241ba15c1c20e6c871e22b1a2f472b 521 Pfam PF13600 N-terminal domain of unknown function (DUF4140) 20 118 1.2E-18 T 13-10-2018 IPR025554 Domain of unknown function DUF4140 THITH_00560 dbb8d41b01ee189e634058c9ae298121 579 Pfam PF00361 Proton-conducting membrane transporter 122 351 1.9E-28 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12370 ddef9d22b92ed3e41ba37adedded165a 471 SUPERFAMILY SSF51649 143 466 6.54E-141 T 13-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THITH_12370 ddef9d22b92ed3e41ba37adedded165a 471 SUPERFAMILY SSF54966 4 141 1.83E-54 T 13-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THITH_12370 ddef9d22b92ed3e41ba37adedded165a 471 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 16 137 1.8E-42 T 13-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THITH_12370 ddef9d22b92ed3e41ba37adedded165a 471 Gene3D G3DSA:3.30.70.150 15 141 3.7E-47 T 13-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THITH_12370 ddef9d22b92ed3e41ba37adedded165a 471 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 147 455 1.8E-129 T 13-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THITH_12370 ddef9d22b92ed3e41ba37adedded165a 471 Gene3D G3DSA:3.20.20.110 143 471 3.3E-152 T 13-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THITH_12370 ddef9d22b92ed3e41ba37adedded165a 471 Hamap MF_01338 Ribulose bisphosphate carboxylase large chain [rbcL]. 2 468 58.542 T 13-10-2018 IPR020888 Ribulose bisphosphate carboxylase large subunit, type I GO:0000287|GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 THITH_13610 99bb1f43678ddf85ab9af903b8815a1d 947 ProSitePatterns PS00781 Phosphoenolpyruvate carboxylase active site 1. 148 159 - T 13-10-2018 IPR018129 Phosphoenolpyruvate carboxylase, Lys active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THITH_13610 99bb1f43678ddf85ab9af903b8815a1d 947 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 147 160 1.1E-56 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THITH_13610 99bb1f43678ddf85ab9af903b8815a1d 947 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 424 444 1.1E-56 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THITH_13610 99bb1f43678ddf85ab9af903b8815a1d 947 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 631 660 1.1E-56 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THITH_13610 99bb1f43678ddf85ab9af903b8815a1d 947 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 589 609 1.1E-56 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THITH_13610 99bb1f43678ddf85ab9af903b8815a1d 947 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 264 279 1.1E-56 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THITH_13610 99bb1f43678ddf85ab9af903b8815a1d 947 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 767 793 1.1E-56 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THITH_13610 99bb1f43678ddf85ab9af903b8815a1d 947 PRINTS PR00150 Phosphoenolpyruvate carboxylase signature 200 216 1.1E-56 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THITH_13610 99bb1f43678ddf85ab9af903b8815a1d 947 Hamap MF_00595 Phosphoenolpyruvate carboxylase [ppc]. 10 947 17.081 T 13-10-2018 IPR022805 Phosphoenolpyruvate carboxylase, bacterial/plant-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THITH_13610 99bb1f43678ddf85ab9af903b8815a1d 947 Gene3D G3DSA:1.20.1440.90 279 427 4.1E-13 T 13-10-2018 THITH_13610 99bb1f43678ddf85ab9af903b8815a1d 947 ProSitePatterns PS00393 Phosphoenolpyruvate carboxylase active site 2. 591 603 - T 13-10-2018 IPR033129 Phosphoenolpyruvate carboxylase, His active site KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THITH_13610 99bb1f43678ddf85ab9af903b8815a1d 947 SUPERFAMILY SSF51621 19 947 1.51E-285 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 THITH_13610 99bb1f43678ddf85ab9af903b8815a1d 947 Pfam PF00311 Phosphoenolpyruvate carboxylase 143 947 4.4E-279 T 13-10-2018 IPR021135 Phosphoenolpyruvate carboxylase GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 THITH_11725 901ba9e1adb58e158acbc0305f1a2aba 638 SUPERFAMILY SSF50465 270 365 1.4E-15 T 13-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal THITH_11725 901ba9e1adb58e158acbc0305f1a2aba 638 SUPERFAMILY SSF50447 173 263 1.93E-18 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THITH_11725 901ba9e1adb58e158acbc0305f1a2aba 638 Gene3D G3DSA:1.10.10.2770 437 569 2.2E-26 T 13-10-2018 THITH_11725 901ba9e1adb58e158acbc0305f1a2aba 638 SUPERFAMILY SSF46785 511 570 7.57E-11 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_11725 901ba9e1adb58e158acbc0305f1a2aba 638 Pfam PF00009 Elongation factor Tu GTP binding domain 2 162 1.7E-27 T 13-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 THITH_11725 901ba9e1adb58e158acbc0305f1a2aba 638 TIGRFAM TIGR00475 selB: selenocysteine-specific translation elongation factor 1 628 6.8E-140 T 13-10-2018 IPR004535 Translation elongation factor, selenocysteine-specific GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 THITH_11725 901ba9e1adb58e158acbc0305f1a2aba 638 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 3 159 8.6E-12 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THITH_11725 901ba9e1adb58e158acbc0305f1a2aba 638 SUPERFAMILY SSF46785 434 505 3.81E-16 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_11725 901ba9e1adb58e158acbc0305f1a2aba 638 Pfam PF09107 Elongation factor SelB, winged helix 584 629 4.3E-18 T 13-10-2018 IPR015191 Translation elongation factor SelB, winged helix, type 3 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 THITH_11725 901ba9e1adb58e158acbc0305f1a2aba 638 SUPERFAMILY SSF46785 588 629 7.62E-8 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_11725 901ba9e1adb58e158acbc0305f1a2aba 638 Gene3D G3DSA:1.10.10.10 571 630 2.4E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_11725 901ba9e1adb58e158acbc0305f1a2aba 638 Gene3D G3DSA:3.40.50.300 1 167 1.2E-46 T 13-10-2018 THITH_11725 901ba9e1adb58e158acbc0305f1a2aba 638 Pfam PF03144 Elongation factor Tu domain 2 191 259 1.2E-8 T 13-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 THITH_11725 901ba9e1adb58e158acbc0305f1a2aba 638 Pfam PF09106 Elongation factor SelB, winged helix 444 500 6.5E-17 T 13-10-2018 IPR015190 Translation elongation factor SelB, winged helix, type 2 GO:0001514|GO:0003723|GO:0003746|GO:0005525|GO:0005737 THITH_11725 901ba9e1adb58e158acbc0305f1a2aba 638 Gene3D G3DSA:2.40.30.10 174 287 5.9E-28 T 13-10-2018 THITH_11725 901ba9e1adb58e158acbc0305f1a2aba 638 SUPERFAMILY SSF52540 2 164 4.53E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_07245 0849d52db55b8aa1e998cfbd7d519902 502 Pfam PF01926 50S ribosome-binding GTPase 271 359 4.1E-10 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_07245 0849d52db55b8aa1e998cfbd7d519902 502 Gene3D G3DSA:3.40.50.300 255 410 2.4E-18 T 13-10-2018 THITH_07245 0849d52db55b8aa1e998cfbd7d519902 502 SUPERFAMILY SSF52540 260 396 3.72E-17 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 315 637 9.8E-126 T 13-10-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 132 149 2.3E-87 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 294 310 2.3E-87 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 310 329 2.3E-87 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 274 294 2.3E-87 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 210 236 2.3E-87 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 244 264 2.3E-87 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 80 106 2.3E-87 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 159 181 2.3E-87 T 13-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 Pfam PF01578 Cytochrome C assembly protein 89 295 2.2E-50 T 13-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 313 328 1.2E-58 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 351 368 1.2E-58 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 113 136 1.2E-58 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 394 413 1.2E-58 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 630 643 1.2E-58 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 4 28 1.2E-58 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 PRINTS PR01411 Cytochrome c-type biogenesis protein CcmF signature 189 204 1.2E-58 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_16200 690e48c1c251bff9005a0c5d269b878f 664 TIGRFAM TIGR00353 nrfE: cytochrome c-type biogenesis protein CcmF 53 640 1.3E-222 T 13-10-2018 IPR003568 Cytochrome c-type biogenesis protein CcmF GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_05350 91e4835eead2c38fa0a59008da39d843 106 Pfam PF09413 Putative prokaryotic signal transducing protein 1 67 5.5E-16 T 13-10-2018 IPR018551 Domain of unknown function DUF2007 THITH_05350 91e4835eead2c38fa0a59008da39d843 106 SUPERFAMILY SSF54913 1 67 8.0E-6 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THITH_13920 3836c54168677e57c80a1be147438284 137 Pfam PF02472 Biopolymer transport protein ExbD/TolR 11 134 7.0E-28 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 THITH_13920 3836c54168677e57c80a1be147438284 137 Gene3D G3DSA:3.30.420.270 62 130 7.6E-10 T 13-10-2018 THITH_16345 ccf230fb49dc76e1e2e9ad6d20ab6792 835 Pfam PF00343 Carbohydrate phosphorylase 108 818 0.0 T 13-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THITH_16345 ccf230fb49dc76e1e2e9ad6d20ab6792 835 Gene3D G3DSA:3.40.50.2000 35 819 0.0 T 13-10-2018 THITH_16345 ccf230fb49dc76e1e2e9ad6d20ab6792 835 SUPERFAMILY SSF53756 17 822 0.0 T 13-10-2018 THITH_16345 ccf230fb49dc76e1e2e9ad6d20ab6792 835 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 663 675 - T 13-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THITH_16345 ccf230fb49dc76e1e2e9ad6d20ab6792 835 Gene3D G3DSA:3.40.50.2000 479 803 0.0 T 13-10-2018 THITH_16345 ccf230fb49dc76e1e2e9ad6d20ab6792 835 PIRSF PIRSF000460 15 834 2.2E-221 T 13-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THITH_16345 ccf230fb49dc76e1e2e9ad6d20ab6792 835 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 23 818 0.0 T 13-10-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 THITH_07335 2c37b2e68ca5f0047669fe1f2595c52a 596 Gene3D G3DSA:3.40.50.300 20 168 5.0E-6 T 13-10-2018 THITH_07335 2c37b2e68ca5f0047669fe1f2595c52a 596 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 404 584 6.8E-80 T 13-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 THITH_07335 2c37b2e68ca5f0047669fe1f2595c52a 596 Pfam PF01583 Adenylylsulphate kinase 419 572 6.7E-74 T 13-10-2018 THITH_07335 2c37b2e68ca5f0047669fe1f2595c52a 596 SUPERFAMILY SSF50447 215 285 3.74E-11 T 13-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily THITH_07335 2c37b2e68ca5f0047669fe1f2595c52a 596 SUPERFAMILY SSF52540 78 186 3.23E-6 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_07335 2c37b2e68ca5f0047669fe1f2595c52a 596 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 418 590 39.372 T 13-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 THITH_07335 2c37b2e68ca5f0047669fe1f2595c52a 596 SUPERFAMILY SSF52540 416 587 2.2E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_07335 2c37b2e68ca5f0047669fe1f2595c52a 596 Gene3D G3DSA:2.40.30.10 172 284 1.5E-12 T 13-10-2018 THITH_07335 2c37b2e68ca5f0047669fe1f2595c52a 596 Gene3D G3DSA:2.40.30.10 288 390 5.7E-26 T 13-10-2018 THITH_07335 2c37b2e68ca5f0047669fe1f2595c52a 596 Gene3D G3DSA:3.40.50.300 396 588 5.9E-79 T 13-10-2018 THITH_07335 2c37b2e68ca5f0047669fe1f2595c52a 596 SUPERFAMILY SSF50465 289 389 1.97E-23 T 13-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal THITH_02170 dec350574e32edd799690a6dce94d191 128 Gene3D G3DSA:3.40.50.1010 2 124 5.6E-9 T 13-10-2018 THITH_02170 dec350574e32edd799690a6dce94d191 128 SUPERFAMILY SSF88723 4 128 3.92E-19 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_02170 dec350574e32edd799690a6dce94d191 128 Pfam PF01850 PIN domain 4 120 1.2E-11 T 13-10-2018 IPR002716 PIN domain THITH_04070 9daa672b4f5ba17ab01a2bd4c82fb2c3 409 Gene3D G3DSA:3.40.50.1100 69 399 1.0E-163 T 13-10-2018 THITH_04070 9daa672b4f5ba17ab01a2bd4c82fb2c3 409 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 22 405 7.3E-159 T 13-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THITH_04070 9daa672b4f5ba17ab01a2bd4c82fb2c3 409 SUPERFAMILY SSF53686 18 405 1.57E-133 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme THITH_04070 9daa672b4f5ba17ab01a2bd4c82fb2c3 409 Gene3D G3DSA:3.40.50.1100 25 222 1.0E-163 T 13-10-2018 THITH_04070 9daa672b4f5ba17ab01a2bd4c82fb2c3 409 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 68 394 1.3E-47 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme THITH_04070 9daa672b4f5ba17ab01a2bd4c82fb2c3 409 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 97 111 - T 13-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THITH_04070 9daa672b4f5ba17ab01a2bd4c82fb2c3 409 PIRSF PIRSF001413 13 409 1.3E-151 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THITH_04070 9daa672b4f5ba17ab01a2bd4c82fb2c3 409 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 17 407 47.973 T 13-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 THITH_11615 2d645b60e8c20d381846e7595688c7a9 165 Pfam PF04608 Phosphatidylglycerophosphatase A 18 157 1.2E-47 T 13-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 THITH_11615 2d645b60e8c20d381846e7595688c7a9 165 PIRSF PIRSF006162 7 165 4.4E-46 T 13-10-2018 IPR026037 Phosphatidylglycerophosphatase A KEGG: 00564+3.1.3.27|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 THITH_11615 2d645b60e8c20d381846e7595688c7a9 165 SUPERFAMILY SSF101307 12 157 8.11E-41 T 13-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 THITH_01315 7322c1600ef73bdaf81d4db7b16be9ad 218 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 20 204 1.2E-24 T 13-10-2018 THITH_01315 7322c1600ef73bdaf81d4db7b16be9ad 218 SUPERFAMILY SSF53335 1 208 7.11E-34 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_01315 7322c1600ef73bdaf81d4db7b16be9ad 218 Gene3D G3DSA:3.40.50.150 2 215 3.7E-41 T 13-10-2018 THITH_03870 dd848044f6013d4cfdd3fd01cd1a4cf6 450 SUPERFAMILY SSF46689 352 447 9.19E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_03870 dd848044f6013d4cfdd3fd01cd1a4cf6 450 SMART SM00382 158 310 6.8E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_03870 dd848044f6013d4cfdd3fd01cd1a4cf6 450 Gene3D G3DSA:1.10.10.60 404 447 2.3E-17 T 13-10-2018 THITH_03870 dd848044f6013d4cfdd3fd01cd1a4cf6 450 Gene3D G3DSA:3.40.50.2300 1 129 2.9E-33 T 13-10-2018 THITH_03870 dd848044f6013d4cfdd3fd01cd1a4cf6 450 SUPERFAMILY SSF52172 1 181 3.98E-42 T 13-10-2018 IPR011006 CheY-like superfamily THITH_03870 dd848044f6013d4cfdd3fd01cd1a4cf6 450 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 432 450 3.6E-7 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_03870 dd848044f6013d4cfdd3fd01cd1a4cf6 450 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 415 432 3.6E-7 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_03870 dd848044f6013d4cfdd3fd01cd1a4cf6 450 Pfam PF00072 Response regulator receiver domain 1 109 2.3E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_03870 dd848044f6013d4cfdd3fd01cd1a4cf6 450 Pfam PF02954 Bacterial regulatory protein, Fis family 408 446 1.2E-16 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_03870 dd848044f6013d4cfdd3fd01cd1a4cf6 450 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 224 239 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THITH_03870 dd848044f6013d4cfdd3fd01cd1a4cf6 450 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 162 175 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THITH_03870 dd848044f6013d4cfdd3fd01cd1a4cf6 450 SMART SM00448 1 110 2.6E-26 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_03870 dd848044f6013d4cfdd3fd01cd1a4cf6 450 Gene3D G3DSA:3.40.50.300 130 308 3.3E-65 T 13-10-2018 THITH_03870 dd848044f6013d4cfdd3fd01cd1a4cf6 450 SUPERFAMILY SSF52540 138 381 6.9E-74 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_03870 dd848044f6013d4cfdd3fd01cd1a4cf6 450 Pfam PF00158 Sigma-54 interaction domain 139 305 4.4E-66 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THITH_03870 dd848044f6013d4cfdd3fd01cd1a4cf6 450 Gene3D G3DSA:1.10.8.60 309 388 4.3E-23 T 13-10-2018 THITH_11370 2fe8f3f07ac7312733aa1c786545dc80 149 SUPERFAMILY SSF47188 1 126 5.23E-27 T 13-10-2018 IPR035938 Hemerythrin-like superfamily THITH_11370 2fe8f3f07ac7312733aa1c786545dc80 149 Gene3D G3DSA:1.20.120.50 2 131 9.3E-32 T 13-10-2018 IPR035938 Hemerythrin-like superfamily THITH_11370 2fe8f3f07ac7312733aa1c786545dc80 149 Pfam PF01814 Hemerythrin HHE cation binding domain 15 124 1.7E-13 T 13-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 THITH_11370 2fe8f3f07ac7312733aa1c786545dc80 149 TIGRFAM TIGR02481 hemeryth_dom: hemerythrin-like metal-binding domain 5 126 5.6E-29 T 13-10-2018 IPR012827 Haemerythrin, metal-binding domain GO:0046872 THITH_11370 2fe8f3f07ac7312733aa1c786545dc80 149 ProSitePatterns PS00550 Hemerythrin family signature. 57 80 - T 13-10-2018 IPR016131 Haemerythrin, iron-binding site GO:0046872 THITH_09370 9dc06526ddc1b7f0f7612cb1206d05ab 73 Hamap MF_00167 Translational regulator CsrA [csrA]. 1 71 17.607 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 THITH_09370 9dc06526ddc1b7f0f7612cb1206d05ab 73 Pfam PF02599 Global regulator protein family 1 52 1.6E-26 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 THITH_09370 9dc06526ddc1b7f0f7612cb1206d05ab 73 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 6.0E-19 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 THITH_09370 9dc06526ddc1b7f0f7612cb1206d05ab 73 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 55 6.5E-28 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 THITH_09370 9dc06526ddc1b7f0f7612cb1206d05ab 73 SUPERFAMILY SSF117130 1 54 1.57E-20 T 13-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 THITH_09370 9dc06526ddc1b7f0f7612cb1206d05ab 73 Gene3D G3DSA:3.30.70.1680 1 58 6.1E-29 T 13-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 THITH_11010 5c737bd718c491068179799a828b81e2 277 Pfam PF01872 RibD C-terminal domain 37 247 3.5E-13 T 13-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 THITH_11010 5c737bd718c491068179799a828b81e2 277 SUPERFAMILY SSF53597 35 250 2.75E-27 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 THITH_11010 5c737bd718c491068179799a828b81e2 277 Gene3D G3DSA:3.40.430.10 16 277 1.1E-38 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 THITH_06155 6e6ee7b62b0f20e12264e43d03bff580 499 Pfam PF02913 FAD linked oxidases, C-terminal domain 231 470 2.3E-69 T 13-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 THITH_06155 6e6ee7b62b0f20e12264e43d03bff580 499 Gene3D G3DSA:3.30.70.2740 350 431 4.3E-8 T 13-10-2018 THITH_06155 6e6ee7b62b0f20e12264e43d03bff580 499 Gene3D G3DSA:3.30.465.10 110 230 7.6E-36 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 THITH_06155 6e6ee7b62b0f20e12264e43d03bff580 499 SUPERFAMILY SSF55103 204 474 1.1E-79 T 13-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 THITH_06155 6e6ee7b62b0f20e12264e43d03bff580 499 Gene3D G3DSA:1.10.45.10 432 472 8.8E-8 T 13-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 THITH_06155 6e6ee7b62b0f20e12264e43d03bff580 499 Gene3D G3DSA:3.30.43.10 14 108 4.8E-18 T 13-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 THITH_06155 6e6ee7b62b0f20e12264e43d03bff580 499 Gene3D G3DSA:3.30.70.2190 231 344 2.5E-5 T 13-10-2018 THITH_06155 6e6ee7b62b0f20e12264e43d03bff580 499 Pfam PF01565 FAD binding domain 57 192 6.6E-37 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THITH_06155 6e6ee7b62b0f20e12264e43d03bff580 499 SUPERFAMILY SSF56176 22 231 1.87E-65 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 THITH_10705 46989cc51434ebc137adc4d44123ce1e 310 Gene3D G3DSA:1.10.8.300 205 307 2.6E-21 T 13-10-2018 THITH_10705 46989cc51434ebc137adc4d44123ce1e 310 SUPERFAMILY SSF52540 7 289 1.89E-41 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_10705 46989cc51434ebc137adc4d44123ce1e 310 PIRSF PIRSF002849 2 308 9.8E-117 T 13-10-2018 THITH_10705 46989cc51434ebc137adc4d44123ce1e 310 SMART SM00382 40 181 2.0E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_10705 46989cc51434ebc137adc4d44123ce1e 310 Gene3D G3DSA:3.40.50.300 24 189 6.0E-44 T 13-10-2018 THITH_10705 46989cc51434ebc137adc4d44123ce1e 310 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 43 173 3.9E-63 T 13-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 THITH_00825 1c433b7c8fd501f0d3b9e1749a6e51d5 300 Pfam PF13482 RNase_H superfamily 4 166 4.9E-28 T 13-10-2018 IPR038720 YprB, ribonuclease H-like domain THITH_00825 1c433b7c8fd501f0d3b9e1749a6e51d5 300 SUPERFAMILY SSF53098 2 170 2.8E-23 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_00825 1c433b7c8fd501f0d3b9e1749a6e51d5 300 Gene3D G3DSA:1.25.40.10 182 300 7.0E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_02235 65fe4f4647f4dade48d3cf5b5e27aa2b 76 Gene3D G3DSA:3.30.160.250 4 68 4.2E-6 T 13-10-2018 THITH_02235 65fe4f4647f4dade48d3cf5b5e27aa2b 76 SUPERFAMILY SSF143100 7 59 1.31E-12 T 13-10-2018 IPR035069 TTHA1013/TTHA0281-like THITH_13650 ebb325a138f898dc95a3a6a44cd0d306 133 PIRSF PIRSF016821 7 133 2.8E-41 T 13-10-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 THITH_13650 ebb325a138f898dc95a3a6a44cd0d306 133 SMART SM00363 10 72 2.9E-8 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_13650 ebb325a138f898dc95a3a6a44cd0d306 133 Gene3D G3DSA:3.10.290.10 4 109 8.0E-39 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 THITH_13650 ebb325a138f898dc95a3a6a44cd0d306 133 SUPERFAMILY SSF55174 8 104 1.07E-27 T 13-10-2018 THITH_13650 ebb325a138f898dc95a3a6a44cd0d306 133 Pfam PF01479 S4 domain 11 55 4.6E-13 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_04905 a85fb0b610c1a5fefd271e11dfbae37d 1089 Pfam PF02811 PHP domain 17 120 1.3E-13 T 13-10-2018 IPR004013 PHP domain GO:0003824 THITH_04905 a85fb0b610c1a5fefd271e11dfbae37d 1089 Hamap MF_01902 Error-prone DNA polymerase [dnaE2]. 15 1089 13.618 T 13-10-2018 IPR023073 DNA polymerase, error-prone GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_04905 a85fb0b610c1a5fefd271e11dfbae37d 1089 SUPERFAMILY SSF89550 22 95 3.34E-8 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 THITH_04905 a85fb0b610c1a5fefd271e11dfbae37d 1089 Pfam PF14579 Helix-hairpin-helix motif 790 918 5.2E-20 T 13-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_04905 a85fb0b610c1a5fefd271e11dfbae37d 1089 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 16 806 1.3E-153 T 13-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_04905 a85fb0b610c1a5fefd271e11dfbae37d 1089 SMART SM00481 16 83 4.7E-11 T 13-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal THITH_04905 a85fb0b610c1a5fefd271e11dfbae37d 1089 Gene3D G3DSA:3.20.20.140 2 272 2.6E-52 T 13-10-2018 THITH_04905 a85fb0b610c1a5fefd271e11dfbae37d 1089 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 295 716 3.7E-149 T 13-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 THITH_02480 6fbdc4cbfdd86b3d9cb72a86b46f3ec1 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 305 331 7.5E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THITH_02480 6fbdc4cbfdd86b3d9cb72a86b46f3ec1 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 73 96 7.5E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THITH_02480 6fbdc4cbfdd86b3d9cb72a86b46f3ec1 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 137 156 7.5E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THITH_02480 6fbdc4cbfdd86b3d9cb72a86b46f3ec1 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 192 212 7.5E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THITH_02480 6fbdc4cbfdd86b3d9cb72a86b46f3ec1 348 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 53 71 7.5E-60 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THITH_02480 6fbdc4cbfdd86b3d9cb72a86b46f3ec1 348 Gene3D G3DSA:3.30.420.40 159 322 1.6E-127 T 13-10-2018 THITH_02480 6fbdc4cbfdd86b3d9cb72a86b46f3ec1 348 Gene3D G3DSA:3.30.420.40 13 332 1.6E-127 T 13-10-2018 THITH_02480 6fbdc4cbfdd86b3d9cb72a86b46f3ec1 348 Pfam PF06723 MreB/Mbl protein 10 339 2.5E-144 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THITH_02480 6fbdc4cbfdd86b3d9cb72a86b46f3ec1 348 Gene3D G3DSA:3.90.640.10 191 264 1.6E-127 T 13-10-2018 THITH_02480 6fbdc4cbfdd86b3d9cb72a86b46f3ec1 348 SUPERFAMILY SSF53067 9 153 2.02E-36 T 13-10-2018 THITH_02480 6fbdc4cbfdd86b3d9cb72a86b46f3ec1 348 SUPERFAMILY SSF53067 155 340 2.8E-49 T 13-10-2018 THITH_02480 6fbdc4cbfdd86b3d9cb72a86b46f3ec1 348 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 9 339 2.4E-154 T 13-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 THITH_14285 a7528bc4f2770223ad0c8496de674cdc 201 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 12 198 2.5E-66 T 13-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14285 a7528bc4f2770223ad0c8496de674cdc 201 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 4 201 30.346 T 13-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14285 a7528bc4f2770223ad0c8496de674cdc 201 SUPERFAMILY SSF52166 7 200 3.92E-63 T 13-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 THITH_14285 a7528bc4f2770223ad0c8496de674cdc 201 Gene3D G3DSA:3.40.1370.10 1 201 9.6E-62 T 13-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 THITH_14285 a7528bc4f2770223ad0c8496de674cdc 201 Pfam PF00573 Ribosomal protein L4/L1 family 12 198 5.3E-58 T 13-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 THITH_02920 28d132e36c99d95453ab2c2fa727fddd 356 Pfam PF13103 TonB C terminal 267 343 1.1E-10 T 13-10-2018 THITH_02920 28d132e36c99d95453ab2c2fa727fddd 356 TIGRFAM TIGR02794 tolA_full: protein TolA 13 344 1.6E-36 T 13-10-2018 IPR014161 Tol-Pal system, TolA GO:0005215|GO:0016021|GO:0043213 THITH_02920 28d132e36c99d95453ab2c2fa727fddd 356 Gene3D G3DSA:3.30.1150.10 237 355 6.2E-19 T 13-10-2018 THITH_02920 28d132e36c99d95453ab2c2fa727fddd 356 SUPERFAMILY SSF74653 247 352 2.22E-12 T 13-10-2018 THITH_01290 121a8178ae6cb92b1cb144920a1759d7 439 SUPERFAMILY SSF103473 64 437 3.53E-20 T 13-10-2018 IPR036259 MFS transporter superfamily THITH_01290 121a8178ae6cb92b1cb144920a1759d7 439 Gene3D G3DSA:1.20.1250.20 251 438 1.1E-12 T 13-10-2018 THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 Gene3D G3DSA:2.40.10.120 23 254 2.5E-83 T 13-10-2018 THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 Pfam PF13180 PDZ domain 376 455 4.8E-10 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 Pfam PF13180 PDZ domain 262 351 1.1E-13 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 PRINTS PR00834 HtrA/DegQ protease family signature 159 183 6.0E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 PRINTS PR00834 HtrA/DegQ protease family signature 119 139 6.0E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 PRINTS PR00834 HtrA/DegQ protease family signature 301 313 6.0E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 PRINTS PR00834 HtrA/DegQ protease family signature 98 110 6.0E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 PRINTS PR00834 HtrA/DegQ protease family signature 193 210 6.0E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 PRINTS PR00834 HtrA/DegQ protease family signature 215 232 6.0E-51 T 13-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 SMART SM00228 261 343 2.2E-11 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 SMART SM00228 374 454 0.0035 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 SUPERFAMILY SSF50494 23 253 1.69E-68 T 13-10-2018 IPR009003 Peptidase S1, PA clan THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 Gene3D G3DSA:2.30.42.10 256 359 7.4E-26 T 13-10-2018 THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 Gene3D G3DSA:2.30.42.60 368 465 1.9E-16 T 13-10-2018 THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 SUPERFAMILY SSF50156 375 462 9.99E-13 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 SUPERFAMILY SSF50156 219 343 8.68E-25 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 Pfam PF13365 Trypsin-like peptidase domain 89 222 1.1E-35 T 13-10-2018 THITH_12160 9893cc0c2d4c692875f5fbb16e9d4043 466 TIGRFAM TIGR02037 degP_htrA_DO: peptidase Do 24 460 1.2E-146 T 13-10-2018 IPR011782 Peptidase S1C, Do GO:0004252|GO:0006508 THITH_00620 32796cd4699ba06f5ce439eb333a2496 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 5 53 15.066 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_00620 32796cd4699ba06f5ce439eb333a2496 55 Pfam PF00471 Ribosomal protein L33 8 53 1.5E-17 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_00620 32796cd4699ba06f5ce439eb333a2496 55 SUPERFAMILY SSF57829 1 53 9.77E-20 T 13-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 THITH_00620 32796cd4699ba06f5ce439eb333a2496 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 1 55 8.1E-26 T 13-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_00620 32796cd4699ba06f5ce439eb333a2496 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 21 40 - T 13-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_00620 32796cd4699ba06f5ce439eb333a2496 55 Gene3D G3DSA:2.20.28.120 1 55 2.3E-29 T 13-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_00450 3452a7a4babc1dce3b6fb2b693e53b39 101 Pfam PF02416 mttA/Hcf106 family 6 58 5.6E-15 T 13-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 THITH_00450 3452a7a4babc1dce3b6fb2b693e53b39 101 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 48 3.6E-21 T 13-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 THITH_00450 3452a7a4babc1dce3b6fb2b693e53b39 101 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 3 95 22.299 T 13-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 THITH_08970 55e45aef81647517c00dfc6d007bb477 375 Gene3D G3DSA:3.30.70.270 202 369 5.2E-55 T 13-10-2018 THITH_08970 55e45aef81647517c00dfc6d007bb477 375 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 205 364 1.9E-44 T 13-10-2018 IPR000160 GGDEF domain THITH_08970 55e45aef81647517c00dfc6d007bb477 375 SUPERFAMILY SSF55073 213 364 2.75E-46 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_08970 55e45aef81647517c00dfc6d007bb477 375 Pfam PF00990 Diguanylate cyclase, GGDEF domain 208 360 5.7E-45 T 13-10-2018 IPR000160 GGDEF domain THITH_08970 55e45aef81647517c00dfc6d007bb477 375 SMART SM00267 194 364 3.4E-59 T 13-10-2018 IPR000160 GGDEF domain THITH_02060 30f71f66a557742ae9ea6229b394441a 269 SUPERFAMILY SSF52540 24 240 1.31E-54 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_02060 30f71f66a557742ae9ea6229b394441a 269 Gene3D G3DSA:3.40.50.300 21 253 5.5E-58 T 13-10-2018 THITH_02060 30f71f66a557742ae9ea6229b394441a 269 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_02060 30f71f66a557742ae9ea6229b394441a 269 Pfam PF00005 ABC transporter 40 176 1.4E-24 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_02060 30f71f66a557742ae9ea6229b394441a 269 SMART SM00382 49 225 2.2E-12 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_00050 0c8864e3bb8d402ff72fc120ffce7e93 491 Gene3D G3DSA:1.20.5.570 459 491 7.0E-15 T 13-10-2018 THITH_00050 0c8864e3bb8d402ff72fc120ffce7e93 491 Gene3D G3DSA:3.40.1670.10 341 458 5.5E-53 T 13-10-2018 THITH_00050 0c8864e3bb8d402ff72fc120ffce7e93 491 SUPERFAMILY SSF143968 327 489 6.8E-67 T 13-10-2018 THITH_00050 0c8864e3bb8d402ff72fc120ffce7e93 491 SUPERFAMILY SSF50475 7 326 1.26E-128 T 13-10-2018 THITH_00050 0c8864e3bb8d402ff72fc120ffce7e93 491 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 15 435 1.5E-178 T 13-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 THITH_00050 0c8864e3bb8d402ff72fc120ffce7e93 491 Hamap MF_01636 3-octaprenyl-4-hydroxybenzoate carboxy-lyase [ubiD]. 5 491 71.386 T 13-10-2018 IPR023677 UbiD decarboxylyase, bacteria GO:0005886|GO:0006744|GO:0008694 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 THITH_00050 0c8864e3bb8d402ff72fc120ffce7e93 491 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 10 459 4.6E-176 T 13-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 THITH_09305 dd60683978c811712b4ab4e9562f2020 372 Pfam PF09623 CRISPR-associated protein NE0113 (Cas_NE0113) 18 227 7.7E-60 T 13-10-2018 IPR019092 CRISPR-assoc protein, NE0113/Csx13 THITH_09305 dd60683978c811712b4ab4e9562f2020 372 TIGRFAM TIGR02584 cas_NE0113: CRISPR-associated protein, NE0113 family 10 210 2.8E-73 T 13-10-2018 IPR013413 CRISPR-associated protein, NE0113 THITH_11665 3bb47d64519ca94e8e95716608a973b6 195 Pfam PF00384 Molybdopterin oxidoreductase 107 139 1.2E-5 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_11665 3bb47d64519ca94e8e95716608a973b6 195 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 45 102 3.4E-16 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_11665 3bb47d64519ca94e8e95716608a973b6 195 Gene3D G3DSA:2.20.25.90 38 107 3.2E-15 T 13-10-2018 THITH_11665 3bb47d64519ca94e8e95716608a973b6 195 Gene3D G3DSA:3.40.50.740 108 195 3.7E-31 T 13-10-2018 THITH_11665 3bb47d64519ca94e8e95716608a973b6 195 SUPERFAMILY SSF53706 36 195 8.64E-53 T 13-10-2018 THITH_11665 3bb47d64519ca94e8e95716608a973b6 195 SMART SM00926 43 104 4.8E-19 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_00510 4f6b5c4c3d9ef832eca8f114ec940d1c 278 Gene3D G3DSA:3.10.310.10 5 274 1.4E-101 T 13-10-2018 THITH_00510 4f6b5c4c3d9ef832eca8f114ec940d1c 278 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 276 1.8E-89 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 THITH_00510 4f6b5c4c3d9ef832eca8f114ec940d1c 278 Pfam PF01678 Diaminopimelate epimerase 5 126 1.1E-35 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 THITH_00510 4f6b5c4c3d9ef832eca8f114ec940d1c 278 Pfam PF01678 Diaminopimelate epimerase 155 270 7.2E-29 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 THITH_00510 4f6b5c4c3d9ef832eca8f114ec940d1c 278 SUPERFAMILY SSF54506 3 276 3.69E-57 T 13-10-2018 THITH_00510 4f6b5c4c3d9ef832eca8f114ec940d1c 278 Gene3D G3DSA:3.10.310.10 118 265 1.4E-101 T 13-10-2018 THITH_00510 4f6b5c4c3d9ef832eca8f114ec940d1c 278 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 278 39.622 T 13-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 THITH_00510 4f6b5c4c3d9ef832eca8f114ec940d1c 278 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 67 81 - T 13-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 THITH_03235 9b25ed97911123e4e91fa8c2aab6aecb 654 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 54 639 5.9E-100 T 13-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ THITH_03235 9b25ed97911123e4e91fa8c2aab6aecb 654 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 131 567 7.6E-67 T 13-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit THITH_12305 158e9cd62019655b955bb34be8046cd0 347 Gene3D G3DSA:3.40.190.290 112 320 5.9E-45 T 13-10-2018 THITH_12305 158e9cd62019655b955bb34be8046cd0 347 SUPERFAMILY SSF46785 23 123 7.71E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_12305 158e9cd62019655b955bb34be8046cd0 347 SUPERFAMILY SSF53850 112 317 5.85E-42 T 13-10-2018 THITH_12305 158e9cd62019655b955bb34be8046cd0 347 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 40 51 8.4E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_12305 158e9cd62019655b955bb34be8046cd0 347 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 61 8.4E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_12305 158e9cd62019655b955bb34be8046cd0 347 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 61 72 8.4E-7 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_12305 158e9cd62019655b955bb34be8046cd0 347 Gene3D G3DSA:1.10.10.10 23 111 1.3E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_12305 158e9cd62019655b955bb34be8046cd0 347 Pfam PF03466 LysR substrate binding domain 111 312 1.4E-48 T 13-10-2018 IPR005119 LysR, substrate-binding THITH_12305 158e9cd62019655b955bb34be8046cd0 347 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 25 83 4.8E-22 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_13005 a41727f655a32bf92ca00e5bc3c8b79a 258 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 13-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_13005 a41727f655a32bf92ca00e5bc3c8b79a 258 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 248 58.327 T 13-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_13005 a41727f655a32bf92ca00e5bc3c8b79a 258 Gene3D G3DSA:3.20.20.70 1 254 6.4E-97 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_13005 a41727f655a32bf92ca00e5bc3c8b79a 258 Pfam PF00121 Triosephosphate isomerase 5 246 5.7E-87 T 13-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_13005 a41727f655a32bf92ca00e5bc3c8b79a 258 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 239 2.0E-69 T 13-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_13005 a41727f655a32bf92ca00e5bc3c8b79a 258 SUPERFAMILY SSF51351 1 248 4.19E-93 T 13-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 THITH_11180 d72f882abdebb649382b6716c91c385d 79 Gene3D G3DSA:1.10.443.10 1 68 3.8E-13 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 THITH_11180 d72f882abdebb649382b6716c91c385d 79 Pfam PF00589 Phage integrase family 2 55 3.1E-9 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THITH_11180 d72f882abdebb649382b6716c91c385d 79 SUPERFAMILY SSF56349 4 64 3.83E-14 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THITH_01520 2bd3984906aedb7440f9865d66cbf17b 92 Gene3D G3DSA:1.10.3880.10 1 91 1.1E-40 T 13-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 THITH_01520 2bd3984906aedb7440f9865d66cbf17b 92 SUPERFAMILY SSF111148 1 90 1.23E-40 T 13-10-2018 IPR036766 Fe(II) trafficking protein YggX superfamily GO:0005506 THITH_01520 2bd3984906aedb7440f9865d66cbf17b 92 PIRSF PIRSF029827 1 90 3.3E-42 T 13-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 THITH_01520 2bd3984906aedb7440f9865d66cbf17b 92 ProDom PD029191 TRAFFICKING IRON PROBABLE FE2 YGGX FEII 3D-STRUCTURE OXIDATIVE CONTROL DIRECT 1 63 1.0E-23 T 13-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 THITH_01520 2bd3984906aedb7440f9865d66cbf17b 92 Pfam PF04362 Bacterial Fe(2+) trafficking 1 88 5.2E-44 T 13-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 THITH_01520 2bd3984906aedb7440f9865d66cbf17b 92 Hamap MF_00686 Probable Fe(2+)-trafficking protein [yggX]. 1 88 29.18 T 13-10-2018 IPR007457 Fe(II) trafficking protein YggX GO:0005506 THITH_12060 ed24cb266b7f79dcafd65972ab03a4b2 237 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 90 196 3.0E-11 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_12060 ed24cb266b7f79dcafd65972ab03a4b2 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 142 158 1.3E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_12060 ed24cb266b7f79dcafd65972ab03a4b2 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 160 180 1.3E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_12060 ed24cb266b7f79dcafd65972ab03a4b2 237 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.3E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_12060 ed24cb266b7f79dcafd65972ab03a4b2 237 Gene3D G3DSA:1.20.120.1600 17 102 1.4E-59 T 13-10-2018 THITH_12060 ed24cb266b7f79dcafd65972ab03a4b2 237 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 91 193 5.1E-12 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_12060 ed24cb266b7f79dcafd65972ab03a4b2 237 SUPERFAMILY SSF56784 3 224 3.16E-39 T 13-10-2018 IPR036412 HAD-like superfamily THITH_12060 ed24cb266b7f79dcafd65972ab03a4b2 237 Gene3D G3DSA:3.40.50.1000 4 218 1.4E-59 T 13-10-2018 IPR023214 HAD superfamily THITH_12060 ed24cb266b7f79dcafd65972ab03a4b2 237 Pfam PF00702 haloacid dehalogenase-like hydrolase 3 193 2.1E-12 T 13-10-2018 THITH_05390 4664539194617322bd1352b5196baa22 309 Gene3D G3DSA:1.10.3720.10 111 300 4.6E-24 T 13-10-2018 IPR035906 MetI-like superfamily THITH_05390 4664539194617322bd1352b5196baa22 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 133 298 3.8E-24 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THITH_05390 4664539194617322bd1352b5196baa22 309 TIGRFAM TIGR01183 ntrB: nitrate ABC transporter, permease protein 97 296 1.1E-95 T 13-10-2018 IPR005889 Nitrate transport permease GO:0015112|GO:0015706|GO:0016021 THITH_05390 4664539194617322bd1352b5196baa22 309 SUPERFAMILY SSF161098 112 294 8.63E-27 T 13-10-2018 IPR035906 MetI-like superfamily THITH_14450 2e16616ba9defcfe6d7804562e5a9963 314 Gene3D G3DSA:3.30.1490.20 121 185 1.4E-20 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 THITH_14450 2e16616ba9defcfe6d7804562e5a9963 314 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 72 83 - T 13-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_14450 2e16616ba9defcfe6d7804562e5a9963 314 SUPERFAMILY SSF52440 13 105 3.84E-29 T 13-10-2018 IPR016185 Pre-ATP-grasp domain superfamily THITH_14450 2e16616ba9defcfe6d7804562e5a9963 314 Pfam PF01820 D-ala D-ala ligase N-terminus 13 95 1.1E-17 T 13-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_14450 2e16616ba9defcfe6d7804562e5a9963 314 Pfam PF07478 D-ala D-ala ligase C-terminus 116 304 2.0E-50 T 13-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_14450 2e16616ba9defcfe6d7804562e5a9963 314 Gene3D G3DSA:3.40.50.20 6 93 6.4E-29 T 13-10-2018 THITH_14450 2e16616ba9defcfe6d7804562e5a9963 314 SUPERFAMILY SSF56059 106 304 2.57E-50 T 13-10-2018 THITH_14450 2e16616ba9defcfe6d7804562e5a9963 314 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 250 278 - T 13-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_14450 2e16616ba9defcfe6d7804562e5a9963 314 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 13 306 6.4E-93 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_14450 2e16616ba9defcfe6d7804562e5a9963 314 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 12 308 33.802 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_14450 2e16616ba9defcfe6d7804562e5a9963 314 PIRSF PIRSF039102 10 60 1.0E-7 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_14450 2e16616ba9defcfe6d7804562e5a9963 314 PIRSF PIRSF039102 52 311 5.4E-76 T 13-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_17095 54ef7ac4d8ce720b701080f6ae4b82df 179 SUPERFAMILY SSF54611 23 165 2.62E-48 T 13-10-2018 IPR035958 SecB-like superfamily THITH_17095 54ef7ac4d8ce720b701080f6ae4b82df 179 Gene3D G3DSA:3.10.420.10 8 170 6.4E-56 T 13-10-2018 IPR035958 SecB-like superfamily THITH_17095 54ef7ac4d8ce720b701080f6ae4b82df 179 TIGRFAM TIGR00809 secB: protein-export chaperone SecB 22 158 4.7E-51 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THITH_17095 54ef7ac4d8ce720b701080f6ae4b82df 179 Pfam PF02556 Preprotein translocase subunit SecB 20 160 3.0E-53 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THITH_17095 54ef7ac4d8ce720b701080f6ae4b82df 179 Hamap MF_00821 Protein-export protein SecB [secB]. 1 161 31.876 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THITH_17095 54ef7ac4d8ce720b701080f6ae4b82df 179 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 89 109 8.0E-34 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THITH_17095 54ef7ac4d8ce720b701080f6ae4b82df 179 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 27 44 8.0E-34 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THITH_17095 54ef7ac4d8ce720b701080f6ae4b82df 179 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 113 135 8.0E-34 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THITH_17095 54ef7ac4d8ce720b701080f6ae4b82df 179 PRINTS PR01594 Bacterial protein-transport SecB chaperone protein signature 139 157 8.0E-34 T 13-10-2018 IPR003708 Bacterial protein export chaperone SecB GO:0015031|GO:0051082|GO:0051262 THITH_12620 1c27ce94334f353aa12d1ffaa3090f49 220 SUPERFAMILY SSF53335 9 220 1.13E-52 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_12620 1c27ce94334f353aa12d1ffaa3090f49 220 Gene3D G3DSA:3.40.50.150 4 219 2.5E-78 T 13-10-2018 THITH_12620 1c27ce94334f353aa12d1ffaa3090f49 220 Pfam PF01596 O-methyltransferase 21 219 3.6E-66 T 13-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 THITH_02760 932c2cc45195f57dbdc63c2869f861e4 280 Gene3D G3DSA:3.60.110.10 1 272 3.9E-92 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily THITH_02760 932c2cc45195f57dbdc63c2869f861e4 280 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 152 172 - T 13-10-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site THITH_02760 932c2cc45195f57dbdc63c2869f861e4 280 SUPERFAMILY SSF56317 3 267 7.46E-81 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily THITH_02760 932c2cc45195f57dbdc63c2869f861e4 280 Pfam PF00795 Carbon-nitrogen hydrolase 4 256 5.9E-58 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 THITH_02605 3154d4c5b1e155921380c4d2a6e56371 184 SUPERFAMILY SSF55021 11 88 7.05E-14 T 13-10-2018 THITH_02605 3154d4c5b1e155921380c4d2a6e56371 184 SUPERFAMILY SSF55021 96 182 4.58E-18 T 13-10-2018 THITH_02605 3154d4c5b1e155921380c4d2a6e56371 184 Gene3D G3DSA:3.30.70.260 95 180 8.8E-18 T 13-10-2018 THITH_02605 3154d4c5b1e155921380c4d2a6e56371 184 Pfam PF13740 ACT domain 12 82 2.2E-14 T 13-10-2018 THITH_02605 3154d4c5b1e155921380c4d2a6e56371 184 PIRSF PIRSF028103 10 184 3.9E-48 T 13-10-2018 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 THITH_02605 3154d4c5b1e155921380c4d2a6e56371 184 Gene3D G3DSA:3.30.70.260 10 92 6.3E-17 T 13-10-2018 THITH_13830 7aa0281d8de6a388889717696cc8f023 155 Pfam PF12697 Alpha/beta hydrolase family 3 117 7.0E-6 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_13830 7aa0281d8de6a388889717696cc8f023 155 SUPERFAMILY SSF53474 3 144 1.0E-10 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_13830 7aa0281d8de6a388889717696cc8f023 155 Gene3D G3DSA:3.40.50.1820 1 152 3.6E-15 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_14430 b04a3cfab6e405cab9da4f65a4a0c950 306 TIGRFAM TIGR00325 lpxC: UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase 2 291 1.0E-121 T 13-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 THITH_14430 b04a3cfab6e405cab9da4f65a4a0c950 306 Gene3D G3DSA:3.30.1700.10 128 304 5.3E-65 T 13-10-2018 IPR011334 UDP-3-O-acyl N-acetylglucosamine deacetylase, C-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 THITH_14430 b04a3cfab6e405cab9da4f65a4a0c950 306 Gene3D G3DSA:3.30.230.20 1 127 6.7E-50 T 13-10-2018 IPR015870 UDP-3-O-acyl N-acetylglucosamine deacetylase, N-terminal GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 THITH_14430 b04a3cfab6e405cab9da4f65a4a0c950 306 SUPERFAMILY SSF54211 3 124 5.01E-42 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_14430 b04a3cfab6e405cab9da4f65a4a0c950 306 SUPERFAMILY SSF54211 133 278 3.94E-49 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_14430 b04a3cfab6e405cab9da4f65a4a0c950 306 Hamap MF_00388 UDP-3-O-acyl-N-acetylglucosamine deacetylase [lpxC]. 2 279 45.443 T 13-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 THITH_14430 b04a3cfab6e405cab9da4f65a4a0c950 306 Pfam PF03331 UDP-3-O-acyl N-acetylglycosamine deacetylase 4 275 1.5E-105 T 13-10-2018 IPR004463 UDP-3-O-acyl N-acetylglucosamine deacetylase GO:0008759|GO:0009245 KEGG: 00540+3.5.1.108 THITH_17195 505c530305069934a314951020432bb3 220 SMART SM00448 6 119 1.2E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_17195 505c530305069934a314951020432bb3 220 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_17195 505c530305069934a314951020432bb3 220 SUPERFAMILY SSF52172 5 135 5.69E-32 T 13-10-2018 IPR011006 CheY-like superfamily THITH_17195 505c530305069934a314951020432bb3 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 7.7E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_17195 505c530305069934a314951020432bb3 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 7.7E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_17195 505c530305069934a314951020432bb3 220 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 7.7E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_17195 505c530305069934a314951020432bb3 220 Pfam PF00072 Response regulator receiver domain 8 120 1.3E-24 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_17195 505c530305069934a314951020432bb3 220 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 3.9E-17 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_17195 505c530305069934a314951020432bb3 220 SUPERFAMILY SSF46894 142 213 5.78E-21 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THITH_17195 505c530305069934a314951020432bb3 220 SMART SM00421 149 206 2.5E-22 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_17195 505c530305069934a314951020432bb3 220 Gene3D G3DSA:3.40.50.12740 6 212 1.5E-60 T 13-10-2018 THITH_15105 993fa78803d15c25c1c2973965ae3803 113 Pfam PF00436 Single-strand binding protein family 5 93 1.3E-8 T 13-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 THITH_15105 993fa78803d15c25c1c2973965ae3803 113 PIRSF PIRSF002070 2 113 7.7E-16 T 13-10-2018 THITH_15105 993fa78803d15c25c1c2973965ae3803 113 SUPERFAMILY SSF50249 5 108 1.17E-12 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_15105 993fa78803d15c25c1c2973965ae3803 113 Gene3D G3DSA:2.40.50.140 3 113 2.6E-15 T 13-10-2018 THITH_12130 67967d7199699e92dfd09c4fea3d0329 303 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 173 7.2E-25 T 13-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 THITH_12130 67967d7199699e92dfd09c4fea3d0329 303 SUPERFAMILY SSF54814 185 299 2.22E-38 T 13-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 THITH_12130 67967d7199699e92dfd09c4fea3d0329 303 Pfam PF07650 KH domain 212 287 4.7E-18 T 13-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_12130 67967d7199699e92dfd09c4fea3d0329 303 Gene3D G3DSA:3.30.300.20 189 302 7.7E-38 T 13-10-2018 IPR015946 K homology domain-like, alpha/beta THITH_12130 67967d7199699e92dfd09c4fea3d0329 303 Gene3D G3DSA:3.40.50.300 5 186 4.2E-45 T 13-10-2018 THITH_12130 67967d7199699e92dfd09c4fea3d0329 303 Hamap MF_00367 GTPase Era [era]. 9 299 33.397 T 13-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_12130 67967d7199699e92dfd09c4fea3d0329 303 SUPERFAMILY SSF52540 14 186 3.03E-40 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_12130 67967d7199699e92dfd09c4fea3d0329 303 Pfam PF01926 50S ribosome-binding GTPase 14 128 1.3E-22 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_12130 67967d7199699e92dfd09c4fea3d0329 303 TIGRFAM TIGR00436 era: GTP-binding protein Era 13 282 2.0E-76 T 13-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_15515 eaa2e939d7c701e207e2b83ced2ed421 167 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 12 135 2.8E-23 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THITH_15515 eaa2e939d7c701e207e2b83ced2ed421 167 SUPERFAMILY SSF55083 10 156 2.62E-35 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THITH_15515 eaa2e939d7c701e207e2b83ced2ed421 167 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 11 135 2.5E-23 T 13-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THITH_15515 eaa2e939d7c701e207e2b83ced2ed421 167 Gene3D G3DSA:3.30.70.560 8 159 1.3E-30 T 13-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 THITH_11930 e6b1ff065f261130f7e767eb50eda5e7 164 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 130 1.4E-46 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type THITH_11930 e6b1ff065f261130f7e767eb50eda5e7 164 Gene3D G3DSA:1.10.10.10 1 141 8.1E-52 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_11930 e6b1ff065f261130f7e767eb50eda5e7 164 Pfam PF02082 Transcriptional regulator 1 83 9.0E-29 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type THITH_11930 e6b1ff065f261130f7e767eb50eda5e7 164 SUPERFAMILY SSF46785 2 133 9.89E-36 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_11930 e6b1ff065f261130f7e767eb50eda5e7 164 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 13-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site THITH_12330 b64d5419a467cbcf12c4d67ce507a15b 107 Pfam PF00936 BMC domain 9 85 2.9E-25 T 13-10-2018 IPR000249 Microcompartment protein, bacteria THITH_12330 b64d5419a467cbcf12c4d67ce507a15b 107 Gene3D G3DSA:3.30.70.1710 2 91 8.1E-36 T 13-10-2018 THITH_12330 b64d5419a467cbcf12c4d67ce507a15b 107 SUPERFAMILY SSF143414 9 94 1.57E-27 T 13-10-2018 IPR037233 CcmK-like superfamily THITH_12330 b64d5419a467cbcf12c4d67ce507a15b 107 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 9 70 1.0E-18 T 13-10-2018 THITH_12330 b64d5419a467cbcf12c4d67ce507a15b 107 SMART SM00877 8 85 5.3E-30 T 13-10-2018 IPR000249 Microcompartment protein, bacteria THITH_08350 fe70f94ec72527a79e257f592b51ceaf 123 SUPERFAMILY SSF50118 4 110 3.49E-30 T 13-10-2018 THITH_08350 fe70f94ec72527a79e257f592b51ceaf 123 Gene3D G3DSA:2.30.30.110 2 119 1.9E-32 T 13-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THITH_08350 fe70f94ec72527a79e257f592b51ceaf 123 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 9 107 4.6E-19 T 13-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THITH_07740 fc0a74027fd96289a95a2c2d0ecfcfc8 403 PRINTS PR00471 Acetate kinase family signature 377 389 6.9E-35 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THITH_07740 fc0a74027fd96289a95a2c2d0ecfcfc8 403 PRINTS PR00471 Acetate kinase family signature 325 341 6.9E-35 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THITH_07740 fc0a74027fd96289a95a2c2d0ecfcfc8 403 PRINTS PR00471 Acetate kinase family signature 303 316 6.9E-35 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THITH_07740 fc0a74027fd96289a95a2c2d0ecfcfc8 403 PRINTS PR00471 Acetate kinase family signature 180 193 6.9E-35 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THITH_07740 fc0a74027fd96289a95a2c2d0ecfcfc8 403 PRINTS PR00471 Acetate kinase family signature 209 230 6.9E-35 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THITH_07740 fc0a74027fd96289a95a2c2d0ecfcfc8 403 PRINTS PR00471 Acetate kinase family signature 5 16 6.9E-35 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THITH_07740 fc0a74027fd96289a95a2c2d0ecfcfc8 403 Gene3D G3DSA:3.30.420.40 203 402 3.0E-70 T 13-10-2018 THITH_07740 fc0a74027fd96289a95a2c2d0ecfcfc8 403 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 5 16 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THITH_07740 fc0a74027fd96289a95a2c2d0ecfcfc8 403 PIRSF PIRSF000722 1 400 1.1E-132 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THITH_07740 fc0a74027fd96289a95a2c2d0ecfcfc8 403 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 209 226 - T 13-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THITH_07740 fc0a74027fd96289a95a2c2d0ecfcfc8 403 Pfam PF00871 Acetokinase family 5 390 1.8E-100 T 13-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THITH_07740 fc0a74027fd96289a95a2c2d0ecfcfc8 403 SUPERFAMILY SSF53067 166 397 3.89E-74 T 13-10-2018 THITH_07740 fc0a74027fd96289a95a2c2d0ecfcfc8 403 SUPERFAMILY SSF53067 5 202 1.42E-52 T 13-10-2018 THITH_07740 fc0a74027fd96289a95a2c2d0ecfcfc8 403 Hamap MF_00020 Acetate kinase [ackA]. 1 399 149.325 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THITH_07740 fc0a74027fd96289a95a2c2d0ecfcfc8 403 Gene3D G3DSA:3.30.420.40 2 200 2.0E-55 T 13-10-2018 THITH_07740 fc0a74027fd96289a95a2c2d0ecfcfc8 403 TIGRFAM TIGR00016 ackA: acetate kinase 5 395 1.4E-101 T 13-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 THITH_05270 35c6d3128b32ad729c99f128b35251f3 254 Pfam PF01061 ABC-2 type transporter 5 215 3.4E-34 T 13-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 THITH_05270 35c6d3128b32ad729c99f128b35251f3 254 PIRSF PIRSF006648 1 252 1.5E-78 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 THITH_17250 11c7f65f8c8122bf6042fd3a6e7ba07c 169 SUPERFAMILY SSF46785 13 153 4.55E-31 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_17250 11c7f65f8c8122bf6042fd3a6e7ba07c 169 Gene3D G3DSA:1.10.10.10 9 150 1.6E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_17250 11c7f65f8c8122bf6042fd3a6e7ba07c 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 99 115 3.6E-6 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THITH_17250 11c7f65f8c8122bf6042fd3a6e7ba07c 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 63 79 3.6E-6 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THITH_17250 11c7f65f8c8122bf6042fd3a6e7ba07c 169 PRINTS PR00598 Bacterial regulatory protein MarR family signature 80 95 3.6E-6 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THITH_17250 11c7f65f8c8122bf6042fd3a6e7ba07c 169 Pfam PF01047 MarR family 46 104 4.1E-15 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THITH_17250 11c7f65f8c8122bf6042fd3a6e7ba07c 169 SMART SM00347 39 139 3.3E-22 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THITH_16595 ac6e4d2e60f63212dd1cfd271d06dc2a 323 SMART SM00450 221 318 4.1E-20 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_16595 ac6e4d2e60f63212dd1cfd271d06dc2a 323 Pfam PF00581 Rhodanese-like domain 223 314 4.8E-11 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_16595 ac6e4d2e60f63212dd1cfd271d06dc2a 323 SUPERFAMILY SSF52821 199 317 7.99E-29 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_16595 ac6e4d2e60f63212dd1cfd271d06dc2a 323 Pfam PF09335 SNARE associated Golgi protein 61 177 3.9E-25 T 13-10-2018 IPR032816 SNARE associated Golgi protein THITH_16595 ac6e4d2e60f63212dd1cfd271d06dc2a 323 Gene3D G3DSA:3.40.250.10 221 322 1.4E-24 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_14955 efdd5c24b7cd2e79476aee96205befbf 247 Pfam PF02654 Cobalamin-5-phosphate synthase 15 239 3.6E-48 T 13-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 THITH_14955 efdd5c24b7cd2e79476aee96205befbf 247 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 247 41.531 T 13-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 THITH_14955 efdd5c24b7cd2e79476aee96205befbf 247 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 16 240 5.7E-35 T 13-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 THITH_17180 f0294c8465a2e30a2cd8bb296fdb57c7 209 SUPERFAMILY SSF46626 29 115 9.14E-15 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_17180 f0294c8465a2e30a2cd8bb296fdb57c7 209 Gene3D G3DSA:1.10.760.10 41 116 5.7E-17 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_17180 f0294c8465a2e30a2cd8bb296fdb57c7 209 SUPERFAMILY SSF46626 122 208 4.43E-14 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_17180 f0294c8465a2e30a2cd8bb296fdb57c7 209 Gene3D G3DSA:1.10.760.10 119 209 1.9E-17 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_17180 f0294c8465a2e30a2cd8bb296fdb57c7 209 PIRSF PIRSF000005 12 209 2.2E-31 T 13-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 THITH_13670 b814a33e28d01d303445fb58ec1c43f5 341 SUPERFAMILY SSF56281 31 325 2.36E-53 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_13670 b814a33e28d01d303445fb58ec1c43f5 341 Pfam PF00753 Metallo-beta-lactamase superfamily 76 260 2.1E-20 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_13670 b814a33e28d01d303445fb58ec1c43f5 341 SMART SM00849 77 266 1.1E-21 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_13670 b814a33e28d01d303445fb58ec1c43f5 341 Gene3D G3DSA:3.60.15.10 50 288 2.6E-41 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_02075 08be0fe63f57e64eba7bdb9957446315 475 SMART SM00382 183 324 1.1E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_02075 08be0fe63f57e64eba7bdb9957446315 475 Pfam PF00072 Response regulator receiver domain 25 134 8.6E-12 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_02075 08be0fe63f57e64eba7bdb9957446315 475 SUPERFAMILY SSF52172 24 207 4.98E-24 T 13-10-2018 IPR011006 CheY-like superfamily THITH_02075 08be0fe63f57e64eba7bdb9957446315 475 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 375 384 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site THITH_02075 08be0fe63f57e64eba7bdb9957446315 475 Gene3D G3DSA:3.40.50.300 149 332 1.3E-62 T 13-10-2018 THITH_02075 08be0fe63f57e64eba7bdb9957446315 475 SUPERFAMILY SSF52540 164 396 4.2E-69 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_02075 08be0fe63f57e64eba7bdb9957446315 475 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 248 263 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THITH_02075 08be0fe63f57e64eba7bdb9957446315 475 SMART SM00448 23 134 2.1E-9 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_02075 08be0fe63f57e64eba7bdb9957446315 475 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 433 450 1.7E-6 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_02075 08be0fe63f57e64eba7bdb9957446315 475 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 450 470 1.7E-6 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_02075 08be0fe63f57e64eba7bdb9957446315 475 SUPERFAMILY SSF46689 373 468 2.2E-13 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_02075 08be0fe63f57e64eba7bdb9957446315 475 Gene3D G3DSA:1.10.10.60 414 467 1.4E-16 T 13-10-2018 THITH_02075 08be0fe63f57e64eba7bdb9957446315 475 Gene3D G3DSA:1.10.8.60 333 409 4.3E-22 T 13-10-2018 THITH_02075 08be0fe63f57e64eba7bdb9957446315 475 Pfam PF02954 Bacterial regulatory protein, Fis family 426 467 1.3E-13 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_02075 08be0fe63f57e64eba7bdb9957446315 475 Gene3D G3DSA:3.40.50.2300 24 141 1.3E-17 T 13-10-2018 THITH_02075 08be0fe63f57e64eba7bdb9957446315 475 Pfam PF00158 Sigma-54 interaction domain 165 328 6.2E-68 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THITH_05010 94a09ce718cf556a3efb989d26e93a36 635 PIRSF PIRSF037901 2 600 1.8E-208 T 13-10-2018 IPR017315 Peptidase S8A, subtilisin-related, proteobacteria-2 THITH_05010 94a09ce718cf556a3efb989d26e93a36 635 SUPERFAMILY SSF52743 135 404 8.51E-72 T 13-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 THITH_05010 94a09ce718cf556a3efb989d26e93a36 635 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 193 203 - T 13-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site THITH_05010 94a09ce718cf556a3efb989d26e93a36 635 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 343 353 - T 13-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site THITH_05010 94a09ce718cf556a3efb989d26e93a36 635 Pfam PF00082 Subtilase family 151 393 2.3E-34 T 13-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THITH_05010 94a09ce718cf556a3efb989d26e93a36 635 Gene3D G3DSA:3.40.50.200 92 406 1.0E-80 T 13-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 THITH_05010 94a09ce718cf556a3efb989d26e93a36 635 PRINTS PR00723 Subtilisin serine protease family (S8) signature 151 170 3.8E-18 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related THITH_05010 94a09ce718cf556a3efb989d26e93a36 635 PRINTS PR00723 Subtilisin serine protease family (S8) signature 342 358 3.8E-18 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related THITH_05010 94a09ce718cf556a3efb989d26e93a36 635 PRINTS PR00723 Subtilisin serine protease family (S8) signature 189 202 3.8E-18 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related THITH_05010 94a09ce718cf556a3efb989d26e93a36 635 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 156 167 - T 13-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site THITH_05010 94a09ce718cf556a3efb989d26e93a36 635 Gene3D G3DSA:2.60.40.10 513 601 6.7E-19 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_05010 94a09ce718cf556a3efb989d26e93a36 635 Gene3D G3DSA:2.60.40.10 412 504 8.0E-22 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_10715 4447c0ec8f2e1d3efd5f6744240bdfb2 677 SUPERFAMILY SSF54001 278 607 2.8E-52 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily THITH_10715 4447c0ec8f2e1d3efd5f6744240bdfb2 677 Pfam PF13559 Domain of unknown function (DUF4129) 590 662 8.2E-9 T 13-10-2018 IPR025403 Domain of unknown function DUF4129 THITH_10715 4447c0ec8f2e1d3efd5f6744240bdfb2 677 SMART SM00460 405 476 8.8E-20 T 13-10-2018 IPR002931 Transglutaminase-like THITH_10715 4447c0ec8f2e1d3efd5f6744240bdfb2 677 Gene3D G3DSA:3.10.620.30 346 513 1.7E-20 T 13-10-2018 THITH_10715 4447c0ec8f2e1d3efd5f6744240bdfb2 677 Pfam PF11992 Domain of unknown function (DUF3488) 19 328 9.0E-102 T 13-10-2018 IPR021878 Protein of unknown function DUF3488 THITH_10715 4447c0ec8f2e1d3efd5f6744240bdfb2 677 Pfam PF01841 Transglutaminase-like superfamily 379 474 4.5E-23 T 13-10-2018 IPR002931 Transglutaminase-like THITH_14145 8ff5b7f33f46ba3dd2ad3ae0d9e6145b 158 SUPERFAMILY SSF50249 3 158 1.65E-55 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_14145 8ff5b7f33f46ba3dd2ad3ae0d9e6145b 158 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 2 158 3.9E-50 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 THITH_14145 8ff5b7f33f46ba3dd2ad3ae0d9e6145b 158 Hamap MF_00984 Single-stranded DNA-binding protein. 5 113 36.433 T 13-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 THITH_14145 8ff5b7f33f46ba3dd2ad3ae0d9e6145b 158 Pfam PF00436 Single-strand binding protein family 5 109 1.4E-40 T 13-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 THITH_14145 8ff5b7f33f46ba3dd2ad3ae0d9e6145b 158 Gene3D G3DSA:2.40.50.140 1 120 1.3E-46 T 13-10-2018 THITH_00045 38b9a5d6e0ca89baa25a2ce2a02e2a5a 170 Pfam PF03350 Uncharacterized protein family, UPF0114 10 124 7.3E-30 T 13-10-2018 IPR005134 Uncharacterised protein family UPF0114 THITH_00045 38b9a5d6e0ca89baa25a2ce2a02e2a5a 170 TIGRFAM TIGR00645 HI0507: TIGR00645 family protein 1 164 1.1E-59 T 13-10-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria THITH_00045 38b9a5d6e0ca89baa25a2ce2a02e2a5a 170 Hamap MF_00143 UPF0114 protein YqhA [yqhA]. 1 166 72.811 T 13-10-2018 IPR020761 Uncharacterised protein family UPF0114, bacteria THITH_12915 d79a62576985a1b70cba7618b362e01f 154 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 5 150 23.266 T 13-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 THITH_12915 d79a62576985a1b70cba7618b362e01f 154 SUPERFAMILY SSF75420 4 82 5.75E-24 T 13-10-2018 IPR035956 RimP, N-terminal domain superfamily THITH_12915 d79a62576985a1b70cba7618b362e01f 154 Pfam PF17384 RimP C-terminal SH3 domain 85 148 3.9E-14 T 13-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal THITH_12915 d79a62576985a1b70cba7618b362e01f 154 Gene3D G3DSA:3.30.300.70 2 79 7.7E-24 T 13-10-2018 IPR035956 RimP, N-terminal domain superfamily THITH_12915 d79a62576985a1b70cba7618b362e01f 154 SUPERFAMILY SSF74942 83 148 1.14E-13 T 13-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily THITH_12915 d79a62576985a1b70cba7618b362e01f 154 Pfam PF02576 RimP N-terminal domain 11 82 1.6E-25 T 13-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal THITH_11105 449a9c70e575fe41bec643686b8c4afa 89 SUPERFAMILY SSF89447 6 59 3.35E-6 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily THITH_11105 449a9c70e575fe41bec643686b8c4afa 89 Gene3D G3DSA:2.10.260.10 4 86 7.0E-19 T 13-10-2018 THITH_11105 449a9c70e575fe41bec643686b8c4afa 89 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 10 59 5.2E-8 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THITH_11940 d26453ceba4f9fd006cf724cd2c6692f 250 SUPERFAMILY SSF75217 7 164 7.19E-37 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases THITH_11940 d26453ceba4f9fd006cf724cd2c6692f 250 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 6 240 6.1E-69 T 13-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 THITH_11940 d26453ceba4f9fd006cf724cd2c6692f 250 Pfam PF00588 SpoU rRNA Methylase family 8 157 2.7E-34 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 THITH_11940 d26453ceba4f9fd006cf724cd2c6692f 250 Gene3D G3DSA:1.10.8.590 174 248 1.5E-22 T 13-10-2018 THITH_11940 d26453ceba4f9fd006cf724cd2c6692f 250 Gene3D G3DSA:3.40.1280.10 4 169 1.8E-61 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THITH_11940 d26453ceba4f9fd006cf724cd2c6692f 250 PIRSF PIRSF004808 3 245 5.4E-71 T 13-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 THITH_07475 f19dd6aede33eca42435749157059b18 1062 Pfam PF14850 DNA-binding domain of Proline dehydrogenase 66 179 1.2E-42 T 13-10-2018 IPR024082 Proline dehydrogenase PutA, domain II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 THITH_07475 f19dd6aede33eca42435749157059b18 1062 Gene3D G3DSA:3.40.309.10 799 992 8.7E-147 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 THITH_07475 f19dd6aede33eca42435749157059b18 1062 SUPERFAMILY SSF81935 10 180 1.57E-54 T 13-10-2018 IPR024089 Proline dehydrogenase PutA, domain I/II GO:0003842|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 THITH_07475 f19dd6aede33eca42435749157059b18 1062 SUPERFAMILY SSF53720 549 1028 1.57E-122 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 THITH_07475 f19dd6aede33eca42435749157059b18 1062 Gene3D G3DSA:3.20.20.220 139 515 2.0E-134 T 13-10-2018 THITH_07475 f19dd6aede33eca42435749157059b18 1062 Pfam PF00171 Aldehyde dehydrogenase family 567 1021 9.9E-110 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 THITH_07475 f19dd6aede33eca42435749157059b18 1062 Gene3D G3DSA:3.40.605.10 541 1024 8.7E-147 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 THITH_07475 f19dd6aede33eca42435749157059b18 1062 Pfam PF01619 Proline dehydrogenase 194 480 1.9E-91 T 13-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 THITH_07475 f19dd6aede33eca42435749157059b18 1062 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 824 835 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 THITH_07475 f19dd6aede33eca42435749157059b18 1062 SUPERFAMILY SSF51730 182 523 2.98E-113 T 13-10-2018 IPR029041 FAD-linked oxidoreductase-like THITH_07475 f19dd6aede33eca42435749157059b18 1062 PIRSF PIRSF000197 2 1050 0.0 T 13-10-2018 IPR025703 Bifunctional protein PutA GO:0003700|GO:0003842|GO:0004657|GO:0006355|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 THITH_07475 f19dd6aede33eca42435749157059b18 1062 TIGRFAM TIGR01238 D1pyr5carbox3: delta-1-pyrroline-5-carboxylate dehydrogenase 515 1021 9.3E-199 T 13-10-2018 IPR005933 Delta-1-pyrroline-5-carboxylate dehydrogenase 3 GO:0003842|GO:0006561|GO:0055114 KEGG: 00250+1.2.1.88|KEGG: 00330+1.5.5.2+1.2.1.88|MetaCyc: PWY-5737|MetaCyc: PWY-6853|MetaCyc: PWY-6922 THITH_02450 01a3c5229dbb33a402efdf736cd0f994 340 Gene3D G3DSA:3.40.50.2000 169 340 9.1E-55 T 13-10-2018 THITH_02450 01a3c5229dbb33a402efdf736cd0f994 340 TIGRFAM TIGR02195 heptsyl_trn_II: lipopolysaccharide heptosyltransferase II 10 338 6.0E-130 T 13-10-2018 IPR011910 ADP-heptose--LPS heptosyltransferase 2 GO:0009103|GO:0016757 THITH_02450 01a3c5229dbb33a402efdf736cd0f994 340 Gene3D G3DSA:3.40.50.2000 9 155 7.8E-48 T 13-10-2018 THITH_02450 01a3c5229dbb33a402efdf736cd0f994 340 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 76 321 2.9E-64 T 13-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 THITH_02450 01a3c5229dbb33a402efdf736cd0f994 340 SUPERFAMILY SSF53756 10 339 4.55E-88 T 13-10-2018 THITH_08690 970dbb1f334cc03fabdf80881e122308 418 ProSitePatterns PS00211 ABC transporters family signature. 164 178 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_08690 970dbb1f334cc03fabdf80881e122308 418 Gene3D G3DSA:3.10.580.10 291 394 3.1E-6 T 13-10-2018 THITH_08690 970dbb1f334cc03fabdf80881e122308 418 Pfam PF00005 ABC transporter 44 191 7.1E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_08690 970dbb1f334cc03fabdf80881e122308 418 SUPERFAMILY SSF54631 273 392 2.53E-14 T 13-10-2018 THITH_08690 970dbb1f334cc03fabdf80881e122308 418 SMART SM00382 52 249 6.6E-20 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_08690 970dbb1f334cc03fabdf80881e122308 418 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 36 394 8.8E-135 T 13-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 THITH_08690 970dbb1f334cc03fabdf80881e122308 418 Gene3D G3DSA:3.40.50.300 30 289 1.6E-79 T 13-10-2018 THITH_08690 970dbb1f334cc03fabdf80881e122308 418 Pfam PF00571 CBS domain 339 391 7.3E-5 T 13-10-2018 IPR000644 CBS domain THITH_08690 970dbb1f334cc03fabdf80881e122308 418 SUPERFAMILY SSF52540 42 268 4.08E-77 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_06095 927e312a5195c6dba8c35167dd5b6b9b 268 Gene3D G3DSA:3.40.190.80 140 262 8.5E-40 T 13-10-2018 THITH_06095 927e312a5195c6dba8c35167dd5b6b9b 268 Gene3D G3DSA:3.30.540.10 1 138 1.1E-49 T 13-10-2018 THITH_06095 927e312a5195c6dba8c35167dd5b6b9b 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 7.8E-61 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_06095 927e312a5195c6dba8c35167dd5b6b9b 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 128 151 7.8E-61 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_06095 927e312a5195c6dba8c35167dd5b6b9b 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 7.8E-61 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_06095 927e312a5195c6dba8c35167dd5b6b9b 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 206 230 7.8E-61 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_06095 927e312a5195c6dba8c35167dd5b6b9b 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 79 95 7.8E-61 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_06095 927e312a5195c6dba8c35167dd5b6b9b 268 PRINTS PR00377 Inositol monophosphatase superfamily signature 175 196 7.8E-61 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_06095 927e312a5195c6dba8c35167dd5b6b9b 268 PRINTS PR01959 SuhB family inositol monophosphatase signature 17 39 5.5E-27 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 THITH_06095 927e312a5195c6dba8c35167dd5b6b9b 268 PRINTS PR01959 SuhB family inositol monophosphatase signature 154 180 5.5E-27 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 THITH_06095 927e312a5195c6dba8c35167dd5b6b9b 268 PRINTS PR01959 SuhB family inositol monophosphatase signature 102 121 5.5E-27 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 THITH_06095 927e312a5195c6dba8c35167dd5b6b9b 268 PRINTS PR01959 SuhB family inositol monophosphatase signature 196 208 5.5E-27 T 13-10-2018 IPR022337 Inositol monophosphatase, SuhB GO:0008934|GO:0046855 KEGG: 00521+3.1.3.25|KEGG: 00562+3.1.3.25|KEGG: 04070+3.1.3.25|MetaCyc: PWY-2301|MetaCyc: PWY-4702|MetaCyc: PWY-6363 THITH_06095 927e312a5195c6dba8c35167dd5b6b9b 268 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 209 223 - T 13-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 THITH_06095 927e312a5195c6dba8c35167dd5b6b9b 268 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 79 92 - T 13-10-2018 IPR020583 Inositol monophosphatase, metal-binding site THITH_06095 927e312a5195c6dba8c35167dd5b6b9b 268 Pfam PF00459 Inositol monophosphatase family 2 256 1.8E-67 T 13-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 THITH_06095 927e312a5195c6dba8c35167dd5b6b9b 268 SUPERFAMILY SSF56655 1 256 5.89E-88 T 13-10-2018 THITH_17480 b35e5074f1e358005e6d435a9c2289ac 632 Pfam PF01496 V-type ATPase 116kDa subunit family 523 623 1.9E-10 T 13-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_17480 b35e5074f1e358005e6d435a9c2289ac 632 Pfam PF01496 V-type ATPase 116kDa subunit family 144 385 1.1E-19 T 13-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_17480 b35e5074f1e358005e6d435a9c2289ac 632 Gene3D G3DSA:3.30.70.2750 135 211 2.3E-7 T 13-10-2018 THITH_17480 b35e5074f1e358005e6d435a9c2289ac 632 Gene3D G3DSA:1.20.1460.20 54 278 2.3E-7 T 13-10-2018 THITH_17480 b35e5074f1e358005e6d435a9c2289ac 632 Gene3D G3DSA:3.30.70.2170 279 301 2.3E-7 T 13-10-2018 THITH_09985 ea0163cc3e8f3b17f6c0665ca98a9dc1 398 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 4 387 68.502 T 13-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 THITH_09985 ea0163cc3e8f3b17f6c0665ca98a9dc1 398 Pfam PF00202 Aminotransferase class-III 10 382 9.3E-113 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THITH_09985 ea0163cc3e8f3b17f6c0665ca98a9dc1 398 PIRSF PIRSF000521 164 387 3.6E-31 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THITH_09985 ea0163cc3e8f3b17f6c0665ca98a9dc1 398 PIRSF PIRSF000521 1 147 9.0E-14 T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THITH_09985 ea0163cc3e8f3b17f6c0665ca98a9dc1 398 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 7 383 5.2E-139 T 13-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 THITH_09985 ea0163cc3e8f3b17f6c0665ca98a9dc1 398 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 211 248 - T 13-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 THITH_09985 ea0163cc3e8f3b17f6c0665ca98a9dc1 398 SUPERFAMILY SSF53383 7 384 7.12E-127 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_09985 ea0163cc3e8f3b17f6c0665ca98a9dc1 398 Gene3D G3DSA:3.40.640.10 48 295 1.7E-142 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_09985 ea0163cc3e8f3b17f6c0665ca98a9dc1 398 Gene3D G3DSA:3.90.1150.10 7 375 1.7E-142 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_02470 264f51dc6352d97ae5bf8781b0a3d864 163 Pfam PF04093 rod shape-determining protein MreD 12 148 2.1E-22 T 13-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 THITH_02470 264f51dc6352d97ae5bf8781b0a3d864 163 PIRSF PIRSF018472 6 161 8.9E-46 T 13-10-2018 IPR026034 Cell shape-determining protein MreD, proteobacterial type THITH_02470 264f51dc6352d97ae5bf8781b0a3d864 163 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 11 151 7.7E-32 T 13-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 THITH_11655 d74b3aa280c4cb959c01621f6264d842 413 Pfam PF00534 Glycosyl transferases group 1 195 359 7.0E-32 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 THITH_11655 d74b3aa280c4cb959c01621f6264d842 413 Gene3D G3DSA:3.40.50.2000 1 190 3.0E-37 T 13-10-2018 THITH_11655 d74b3aa280c4cb959c01621f6264d842 413 Pfam PF13439 Glycosyltransferase Family 4 14 186 6.9E-34 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 THITH_11655 d74b3aa280c4cb959c01621f6264d842 413 Gene3D G3DSA:3.40.50.2000 191 363 1.4E-42 T 13-10-2018 THITH_11655 d74b3aa280c4cb959c01621f6264d842 413 SUPERFAMILY SSF53756 2 385 1.4E-82 T 13-10-2018 THITH_02590 064c6ed6d0235244027df627966d49d8 253 SUPERFAMILY SSF56281 1 232 1.83E-42 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_02590 064c6ed6d0235244027df627966d49d8 253 Pfam PF12706 Beta-lactamase superfamily domain 22 205 1.1E-22 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_02590 064c6ed6d0235244027df627966d49d8 253 Gene3D G3DSA:3.60.15.10 5 241 1.9E-41 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_02590 064c6ed6d0235244027df627966d49d8 253 SMART SM00849 11 185 9.6E-12 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_12195 120e3789e1629fb617086de241710984 100 Gene3D G3DSA:1.10.760.10 4 96 1.2E-6 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_12195 120e3789e1629fb617086de241710984 100 SUPERFAMILY SSF46626 1 94 3.06E-10 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_12590 9bd1edf8e2ecf6f4d9d738e50e1dac4f 131 Pfam PF03330 Lytic transglycolase 31 121 1.4E-27 T 13-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain THITH_12590 9bd1edf8e2ecf6f4d9d738e50e1dac4f 131 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 34 125 1.7E-43 T 13-10-2018 IPR012997 Rare lipoprotein A THITH_12590 9bd1edf8e2ecf6f4d9d738e50e1dac4f 131 Gene3D G3DSA:2.40.40.10 31 125 7.2E-39 T 13-10-2018 IPR036908 RlpA-like domain superfamily THITH_12590 9bd1edf8e2ecf6f4d9d738e50e1dac4f 131 SUPERFAMILY SSF50685 22 123 2.23E-14 T 13-10-2018 IPR036908 RlpA-like domain superfamily THITH_12590 9bd1edf8e2ecf6f4d9d738e50e1dac4f 131 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 23 124 22.813 T 13-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 THITH_16035 64d69142e1c01bf6af24225979989678 390 Pfam PF00437 Type II/IV secretion system protein 84 277 1.2E-35 T 13-10-2018 IPR001482 Type II/IV secretion system protein THITH_16035 64d69142e1c01bf6af24225979989678 390 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 10 350 1.4E-136 T 13-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 THITH_16035 64d69142e1c01bf6af24225979989678 390 Gene3D G3DSA:3.30.450.90 2 107 3.7E-30 T 13-10-2018 THITH_16035 64d69142e1c01bf6af24225979989678 390 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 200 214 - T 13-10-2018 IPR001482 Type II/IV secretion system protein THITH_16035 64d69142e1c01bf6af24225979989678 390 Gene3D G3DSA:3.40.50.300 108 366 2.6E-86 T 13-10-2018 THITH_16035 64d69142e1c01bf6af24225979989678 390 SUPERFAMILY SSF52540 4 344 1.22E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01180 19e3b5af8a76b44d0fa4256d272f3bd5 70 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 70 1.4E-18 T 13-10-2018 IPR010035 ThiS, thiamine-biosynthesis THITH_01180 19e3b5af8a76b44d0fa4256d272f3bd5 70 Pfam PF02597 ThiS family 3 70 1.3E-15 T 13-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 THITH_01180 19e3b5af8a76b44d0fa4256d272f3bd5 70 Gene3D G3DSA:3.10.20.30 1 70 3.0E-20 T 13-10-2018 IPR012675 Beta-grasp domain superfamily THITH_01180 19e3b5af8a76b44d0fa4256d272f3bd5 70 SUPERFAMILY SSF54285 2 69 6.71E-16 T 13-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp THITH_04340 cb18fa4561aab28514f71b24c4f93bd7 604 SUPERFAMILY SSF48208 200 526 1.02E-26 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 THITH_04340 cb18fa4561aab28514f71b24c4f93bd7 604 PIRSF PIRSF006402 15 571 1.1E-111 T 13-10-2018 IPR024705 Spermatogenesis-associated protein 20 THITH_04340 cb18fa4561aab28514f71b24c4f93bd7 604 SUPERFAMILY SSF52833 20 151 4.33E-19 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_04340 cb18fa4561aab28514f71b24c4f93bd7 604 Gene3D G3DSA:3.40.30.10 18 178 1.5E-39 T 13-10-2018 THITH_04340 cb18fa4561aab28514f71b24c4f93bd7 604 Pfam PF03190 Protein of unknown function, DUF255 21 163 1.7E-42 T 13-10-2018 IPR004879 Domain of unknown function DUF255 THITH_08420 9ef24c1aca8684051bd324f996bb018a 189 Pfam PF05573 NosL 19 165 2.8E-52 T 13-10-2018 IPR008719 Nitrous oxide reductase accessory protein NosL THITH_08420 9ef24c1aca8684051bd324f996bb018a 189 Gene3D G3DSA:3.30.70.2050 120 183 1.6E-7 T 13-10-2018 THITH_08420 9ef24c1aca8684051bd324f996bb018a 189 SUPERFAMILY SSF160387 57 176 2.88E-33 T 13-10-2018 THITH_08420 9ef24c1aca8684051bd324f996bb018a 189 Gene3D G3DSA:3.30.70.2060 57 119 1.3E-13 T 13-10-2018 THITH_10455 eea2f50a278bd8532ca876350f8fd2e6 289 Gene3D G3DSA:1.10.286.20 188 234 5.4E-45 T 13-10-2018 THITH_10455 eea2f50a278bd8532ca876350f8fd2e6 289 Gene3D G3DSA:3.30.479.20 56 145 1.3E-26 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 THITH_10455 eea2f50a278bd8532ca876350f8fd2e6 289 Hamap MF_00050 Elongation factor Ts [tsf]. 1 286 81.99 T 13-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THITH_10455 eea2f50a278bd8532ca876350f8fd2e6 289 Gene3D G3DSA:3.30.479.20 152 268 5.4E-45 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 THITH_10455 eea2f50a278bd8532ca876350f8fd2e6 289 SUPERFAMILY SSF54713 148 287 4.45E-54 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 THITH_10455 eea2f50a278bd8532ca876350f8fd2e6 289 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 286 1.2E-109 T 13-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THITH_10455 eea2f50a278bd8532ca876350f8fd2e6 289 Pfam PF00889 Elongation factor TS 70 269 5.4E-71 T 13-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 THITH_10455 eea2f50a278bd8532ca876350f8fd2e6 289 SUPERFAMILY SSF46934 1 55 8.29E-19 T 13-10-2018 IPR009060 UBA-like superfamily GO:0005515 THITH_10455 eea2f50a278bd8532ca876350f8fd2e6 289 Gene3D G3DSA:1.10.8.10 1 55 3.9E-26 T 13-10-2018 THITH_10455 eea2f50a278bd8532ca876350f8fd2e6 289 ProSitePatterns PS01127 Elongation factor Ts signature 2. 74 84 - T 13-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THITH_10455 eea2f50a278bd8532ca876350f8fd2e6 289 SUPERFAMILY SSF54713 55 144 6.38E-21 T 13-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 THITH_10455 eea2f50a278bd8532ca876350f8fd2e6 289 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 13-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 THITH_11085 49b4ea79139cd697c2ab96c349fd4e37 87 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 7 86 3.9E-25 T 13-10-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 THITH_11085 49b4ea79139cd697c2ab96c349fd4e37 87 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 85 1.9E-8 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THITH_11085 49b4ea79139cd697c2ab96c349fd4e37 87 Gene3D G3DSA:3.30.2310.20 3 86 1.8E-11 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_11085 49b4ea79139cd697c2ab96c349fd4e37 87 SUPERFAMILY SSF143011 2 87 4.58E-17 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_11085 49b4ea79139cd697c2ab96c349fd4e37 87 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 4 85 4.3E-8 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THITH_16705 b048cf5fbd3a8d677198ce6edc0f4dd0 231 Gene3D G3DSA:1.20.950.20 1 175 7.9E-18 T 13-10-2018 THITH_16705 b048cf5fbd3a8d677198ce6edc0f4dd0 231 SUPERFAMILY SSF81342 9 192 2.98E-25 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THITH_16705 b048cf5fbd3a8d677198ce6edc0f4dd0 231 Pfam PF01292 Prokaryotic cytochrome b561 12 187 3.0E-17 T 13-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THITH_07425 bfb42e1352d9fa0472b31357aede8cbe 527 Gene3D G3DSA:1.10.246.130 249 348 4.3E-8 T 13-10-2018 THITH_07425 bfb42e1352d9fa0472b31357aede8cbe 527 Gene3D G3DSA:3.60.20.40 349 524 2.4E-39 T 13-10-2018 THITH_07425 bfb42e1352d9fa0472b31357aede8cbe 527 Pfam PF01019 Gamma-glutamyltranspeptidase 28 520 9.6E-103 T 13-10-2018 THITH_07425 bfb42e1352d9fa0472b31357aede8cbe 527 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 13 518 5.5E-108 T 13-10-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-4061|MetaCyc: PWY-5826|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7559 THITH_07425 bfb42e1352d9fa0472b31357aede8cbe 527 SUPERFAMILY SSF56235 8 523 8.88E-114 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_07425 bfb42e1352d9fa0472b31357aede8cbe 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 263 282 4.1E-52 T 13-10-2018 THITH_07425 bfb42e1352d9fa0472b31357aede8cbe 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 348 366 4.1E-52 T 13-10-2018 THITH_07425 bfb42e1352d9fa0472b31357aede8cbe 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 113 131 4.1E-52 T 13-10-2018 THITH_07425 bfb42e1352d9fa0472b31357aede8cbe 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 131 150 4.1E-52 T 13-10-2018 THITH_07425 bfb42e1352d9fa0472b31357aede8cbe 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 233 249 4.1E-52 T 13-10-2018 THITH_07425 bfb42e1352d9fa0472b31357aede8cbe 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 401 416 4.1E-52 T 13-10-2018 THITH_07425 bfb42e1352d9fa0472b31357aede8cbe 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 370 388 4.1E-52 T 13-10-2018 THITH_07425 bfb42e1352d9fa0472b31357aede8cbe 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 35 60 4.1E-52 T 13-10-2018 THITH_07425 bfb42e1352d9fa0472b31357aede8cbe 527 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 425 442 4.1E-52 T 13-10-2018 THITH_11305 df52a7a69ca54ed7e75e504fa30f523d 366 Pfam PF15887 Putative zinc-binding metallo-peptidase 101 350 1.0E-104 T 13-10-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase THITH_11305 df52a7a69ca54ed7e75e504fa30f523d 366 PIRSF PIRSF012641 1 364 1.4E-135 T 13-10-2018 IPR031321 Uncharacterised conserved protein UCP012641, putative zinc-binding metallo-peptidase THITH_11305 df52a7a69ca54ed7e75e504fa30f523d 366 Pfam PF10005 zinc-ribbon domain 3 96 2.4E-32 T 13-10-2018 IPR011201 Zinc-ribbon domain, bacteria THITH_05450 f55e543ee089730ebaae00cb351af79b 233 Pfam PF13649 Methyltransferase domain 27 120 1.3E-15 T 13-10-2018 THITH_05450 f55e543ee089730ebaae00cb351af79b 233 Gene3D G3DSA:3.40.50.150 9 200 2.9E-26 T 13-10-2018 THITH_05450 f55e543ee089730ebaae00cb351af79b 233 SUPERFAMILY SSF53335 13 135 8.44E-28 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_11685 731f1402ff43dff71c0c47bc4c2174dc 316 SUPERFAMILY SSF144020 19 309 4.18E-83 T 13-10-2018 IPR024064 FdhE-like superfamily THITH_11685 731f1402ff43dff71c0c47bc4c2174dc 316 Pfam PF04216 Protein involved in formate dehydrogenase formation 16 306 1.4E-102 T 13-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 THITH_11685 731f1402ff43dff71c0c47bc4c2174dc 316 TIGRFAM TIGR01562 FdhE: formate dehydrogenase accessory protein FdhE 3 308 4.6E-88 T 13-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 THITH_11685 731f1402ff43dff71c0c47bc4c2174dc 316 Gene3D G3DSA:3.90.1670.10 18 311 3.6E-95 T 13-10-2018 IPR024064 FdhE-like superfamily THITH_11685 731f1402ff43dff71c0c47bc4c2174dc 316 PIRSF PIRSF018296 1 312 3.4E-98 T 13-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 THITH_11685 731f1402ff43dff71c0c47bc4c2174dc 316 Hamap MF_00611 Protein FdhE [fdhE]. 2 309 37.228 T 13-10-2018 IPR006452 Formate dehydrogenase accessory protein GO:0005737 THITH_09700 f9dd38a4f277f8c970326d2bdc9cf3af 614 SUPERFAMILY SSF55486 161 387 8.06E-38 T 13-10-2018 THITH_09700 f9dd38a4f277f8c970326d2bdc9cf3af 614 Pfam PF01433 Peptidase family M1 domain 239 378 1.2E-7 T 13-10-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 THITH_09700 f9dd38a4f277f8c970326d2bdc9cf3af 614 Gene3D G3DSA:1.10.390.60 156 383 1.1E-26 T 13-10-2018 THITH_14855 69ba0a93466132c7223fae15ab368c33 292 Pfam PF00294 pfkB family carbohydrate kinase 3 274 3.2E-31 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB THITH_14855 69ba0a93466132c7223fae15ab368c33 292 Gene3D G3DSA:3.40.1190.20 2 283 3.8E-68 T 13-10-2018 IPR029056 Ribokinase-like THITH_14855 69ba0a93466132c7223fae15ab368c33 292 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 237 250 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 THITH_14855 69ba0a93466132c7223fae15ab368c33 292 SUPERFAMILY SSF53613 3 278 1.87E-46 T 13-10-2018 IPR029056 Ribokinase-like THITH_02410 1a97eba4a646dace151d196a06e02086 307 PIRSF PIRSF026649 6 306 8.6E-94 T 13-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 THITH_02410 1a97eba4a646dace151d196a06e02086 307 Hamap MF_01942 Lipid A biosynthesis lauroyltransferase [lpxL]. 7 306 43.47 T 13-10-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 THITH_02410 1a97eba4a646dace151d196a06e02086 307 TIGRFAM TIGR02207 lipid_A_htrB: lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase 15 300 5.6E-98 T 13-10-2018 IPR011920 Lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase GO:0009245|GO:0016021|GO:0016740 THITH_02410 1a97eba4a646dace151d196a06e02086 307 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 17 297 1.5E-69 T 13-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 THITH_08195 1878707af1e1941573bffc9fc1c3e284 1252 Gene3D G3DSA:3.40.50.12440 44 1250 0.0 T 13-10-2018 THITH_08195 1878707af1e1941573bffc9fc1c3e284 1252 Pfam PF01568 Molydopterin dinucleotide binding domain 1092 1207 3.5E-19 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 THITH_08195 1878707af1e1941573bffc9fc1c3e284 1252 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 48 66 - T 13-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 THITH_08195 1878707af1e1941573bffc9fc1c3e284 1252 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 3 40 5.7E-17 T 13-10-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 THITH_08195 1878707af1e1941573bffc9fc1c3e284 1252 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 2 1240 0.0 T 13-10-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 THITH_08195 1878707af1e1941573bffc9fc1c3e284 1252 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 781 798 - T 13-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 THITH_08195 1878707af1e1941573bffc9fc1c3e284 1252 SUPERFAMILY SSF50692 1084 1239 2.94E-43 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily THITH_08195 1878707af1e1941573bffc9fc1c3e284 1252 Pfam PF00384 Molybdopterin oxidoreductase 108 836 8.3E-164 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_08195 1878707af1e1941573bffc9fc1c3e284 1252 SMART SM00926 43 105 2.6E-6 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_08195 1878707af1e1941573bffc9fc1c3e284 1252 SUPERFAMILY SSF53706 3 1075 0.0 T 13-10-2018 THITH_14715 25113f80ce303c87942e708ae0745059 209 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 7 199 9.9E-61 T 13-10-2018 IPR004507 Flavin prenyltransferase UbiX-like THITH_14715 25113f80ce303c87942e708ae0745059 209 Gene3D G3DSA:3.40.50.1950 2 203 7.6E-76 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 THITH_14715 25113f80ce303c87942e708ae0745059 209 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 4 201 36.01 T 13-10-2018 IPR004507 Flavin prenyltransferase UbiX-like THITH_14715 25113f80ce303c87942e708ae0745059 209 SUPERFAMILY SSF52507 6 201 3.53E-56 T 13-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 THITH_14715 25113f80ce303c87942e708ae0745059 209 Pfam PF02441 Flavoprotein 6 180 2.5E-21 T 13-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 THITH_14050 3906c37ece95cb7e9b6c92fdd881c8c7 336 Gene3D G3DSA:1.10.8.60 143 210 6.9E-20 T 13-10-2018 THITH_14050 3906c37ece95cb7e9b6c92fdd881c8c7 336 Pfam PF06144 DNA polymerase III, delta subunit 20 189 4.8E-20 T 13-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 THITH_14050 3906c37ece95cb7e9b6c92fdd881c8c7 336 Gene3D G3DSA:3.40.50.300 1 139 4.3E-42 T 13-10-2018 THITH_14050 3906c37ece95cb7e9b6c92fdd881c8c7 336 SUPERFAMILY SSF48019 210 329 2.89E-17 T 13-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 THITH_14050 3906c37ece95cb7e9b6c92fdd881c8c7 336 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 16 328 4.5E-67 T 13-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 THITH_14050 3906c37ece95cb7e9b6c92fdd881c8c7 336 SUPERFAMILY SSF52540 3 208 9.74E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14050 3906c37ece95cb7e9b6c92fdd881c8c7 336 Gene3D G3DSA:1.20.272.10 213 336 1.3E-19 T 13-10-2018 THITH_06595 1dac7bfe58b3810c98826e5ad9ffe2f5 207 Gene3D G3DSA:2.102.10.10 66 205 3.1E-29 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THITH_06595 1dac7bfe58b3810c98826e5ad9ffe2f5 207 SUPERFAMILY SSF50022 69 204 5.56E-11 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THITH_17255 4d11d44b37d479174db944910bb97801 354 Pfam PF13609 Gram-negative porin 8 323 2.0E-30 T 13-10-2018 THITH_17255 4d11d44b37d479174db944910bb97801 354 SUPERFAMILY SSF56935 31 354 1.81E-38 T 13-10-2018 THITH_17255 4d11d44b37d479174db944910bb97801 354 Gene3D G3DSA:2.40.160.10 26 354 2.1E-37 T 13-10-2018 IPR023614 Porin domain superfamily THITH_11420 69943bcf21646aa4a522dcfbe61fbfe7 418 Gene3D G3DSA:3.30.9.50 82 275 6.2E-82 T 13-10-2018 THITH_11420 69943bcf21646aa4a522dcfbe61fbfe7 418 SUPERFAMILY SSF51905 9 398 7.2E-50 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_11420 69943bcf21646aa4a522dcfbe61fbfe7 418 TIGRFAM TIGR01988 Ubi-OHases: ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family 9 392 6.4E-95 T 13-10-2018 IPR010971 Ubiquinone biosynthesis hydroxylase UbiH/COQ6 GO:0006744|GO:0016709|GO:0050660|GO:0055114 Reactome: R-HSA-2142789 THITH_11420 69943bcf21646aa4a522dcfbe61fbfe7 418 Pfam PF01494 FAD binding domain 8 342 1.4E-33 T 13-10-2018 IPR002938 FAD-binding domain GO:0071949 THITH_11420 69943bcf21646aa4a522dcfbe61fbfe7 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 161 176 4.5E-20 T 13-10-2018 THITH_11420 69943bcf21646aa4a522dcfbe61fbfe7 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 301 4.5E-20 T 13-10-2018 THITH_11420 69943bcf21646aa4a522dcfbe61fbfe7 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 4.5E-20 T 13-10-2018 THITH_11420 69943bcf21646aa4a522dcfbe61fbfe7 418 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 9 31 4.5E-20 T 13-10-2018 THITH_11420 69943bcf21646aa4a522dcfbe61fbfe7 418 Gene3D G3DSA:3.50.50.60 9 340 6.2E-82 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_12030 773ab25f06d1ed38862c59effb3cbb85 248 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 9 37 4.3E-4 T 13-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THITH_12030 773ab25f06d1ed38862c59effb3cbb85 248 SUPERFAMILY SSF54862 48 246 1.15E-48 T 13-10-2018 THITH_12030 773ab25f06d1ed38862c59effb3cbb85 248 Gene3D G3DSA:3.30.70.20 51 245 4.0E-54 T 13-10-2018 THITH_12030 773ab25f06d1ed38862c59effb3cbb85 248 Pfam PF13247 4Fe-4S dicluster domain 106 203 2.0E-13 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_12030 773ab25f06d1ed38862c59effb3cbb85 248 Gene3D G3DSA:3.30.70.20 116 180 4.0E-54 T 13-10-2018 THITH_12030 773ab25f06d1ed38862c59effb3cbb85 248 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 142 153 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_04680 2bef4e242e867127ff798149c88f0f77 111 SUPERFAMILY SSF54909 1 66 1.69E-9 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel THITH_12110 c539746cd710bd3dadf496ffba27dad2 291 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 27 45 - T 13-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 THITH_12110 c539746cd710bd3dadf496ffba27dad2 291 TIGRFAM TIGR01136 cysKM: cysteine synthase 2 289 1.0E-124 T 13-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 THITH_12110 c539746cd710bd3dadf496ffba27dad2 291 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 2 278 1.6E-72 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme THITH_12110 c539746cd710bd3dadf496ffba27dad2 291 SUPERFAMILY SSF53686 3 286 2.49E-94 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme THITH_12110 c539746cd710bd3dadf496ffba27dad2 291 TIGRFAM TIGR01138 cysM: cysteine synthase B 1 289 1.7E-149 T 13-10-2018 IPR005858 Cysteine synthase CysM GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 THITH_12110 c539746cd710bd3dadf496ffba27dad2 291 Gene3D G3DSA:3.40.50.1100 5 285 8.1E-114 T 13-10-2018 THITH_12110 c539746cd710bd3dadf496ffba27dad2 291 Gene3D G3DSA:3.40.50.1100 32 137 8.1E-114 T 13-10-2018 THITH_09885 e1091cc6e70c1df6951920d22737484f 264 Pfam PF01061 ABC-2 type transporter 19 224 3.9E-29 T 13-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 THITH_15505 ea829e3ed31739d28b42c1efa808665f 112 SUPERFAMILY SSF54913 1 112 3.18E-46 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THITH_15505 ea829e3ed31739d28b42c1efa808665f 112 PIRSF PIRSF039144 1 112 1.4E-55 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THITH_15505 ea829e3ed31739d28b42c1efa808665f 112 PRINTS PR00340 P-II protein signature 83 103 1.4E-43 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THITH_15505 ea829e3ed31739d28b42c1efa808665f 112 PRINTS PR00340 P-II protein signature 2 17 1.4E-43 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THITH_15505 ea829e3ed31739d28b42c1efa808665f 112 PRINTS PR00340 P-II protein signature 23 41 1.4E-43 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THITH_15505 ea829e3ed31739d28b42c1efa808665f 112 PRINTS PR00340 P-II protein signature 52 75 1.4E-43 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THITH_15505 ea829e3ed31739d28b42c1efa808665f 112 SMART SM00938 4 105 6.0E-67 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THITH_15505 ea829e3ed31739d28b42c1efa808665f 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 13-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 THITH_15505 ea829e3ed31739d28b42c1efa808665f 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 13-10-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 THITH_15505 ea829e3ed31739d28b42c1efa808665f 112 Gene3D G3DSA:3.30.70.120 1 112 6.3E-47 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THITH_15505 ea829e3ed31739d28b42c1efa808665f 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 4.3E-43 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THITH_02435 d54ee81b26fa5377357ee54baa46aa90 322 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 241 7.9E-46 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 THITH_02435 d54ee81b26fa5377357ee54baa46aa90 322 SUPERFAMILY SSF51735 1 308 2.14E-63 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_02435 d54ee81b26fa5377357ee54baa46aa90 322 Gene3D G3DSA:3.40.50.720 3 308 8.6E-121 T 13-10-2018 THITH_02435 d54ee81b26fa5377357ee54baa46aa90 322 Hamap MF_01601 ADP-L-glycero-D-manno-heptose-6-epimerase [hldD]. 1 314 50.537 T 13-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 THITH_02435 d54ee81b26fa5377357ee54baa46aa90 322 TIGRFAM TIGR02197 heptose_epim: ADP-glyceromanno-heptose 6-epimerase 2 311 5.7E-129 T 13-10-2018 IPR011912 ADP-L-glycero-D-manno-heptose-6-epimerase GO:0005975|GO:0008712|GO:0050661 KEGG: 00540+5.1.3.20 THITH_02435 d54ee81b26fa5377357ee54baa46aa90 322 Gene3D G3DSA:3.90.25.10 167 295 8.6E-121 T 13-10-2018 THITH_04845 b7b2677a3c6c1d73a15b38891e4b7fc1 380 PIRSF PIRSF038945 1 377 1.4E-156 T 13-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 THITH_04845 b7b2677a3c6c1d73a15b38891e4b7fc1 380 Gene3D G3DSA:3.40.50.1100 65 161 1.2E-117 T 13-10-2018 THITH_04845 b7b2677a3c6c1d73a15b38891e4b7fc1 380 Gene3D G3DSA:3.40.50.1100 17 351 1.2E-117 T 13-10-2018 THITH_04845 b7b2677a3c6c1d73a15b38891e4b7fc1 380 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 57 70 - T 13-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 THITH_04845 b7b2677a3c6c1d73a15b38891e4b7fc1 380 SUPERFAMILY SSF53686 8 377 4.06E-105 T 13-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme THITH_04845 b7b2677a3c6c1d73a15b38891e4b7fc1 380 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 27 344 5.2E-69 T 13-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme THITH_04845 b7b2677a3c6c1d73a15b38891e4b7fc1 380 TIGRFAM TIGR00260 thrC: threonine synthase 11 351 6.7E-92 T 13-10-2018 IPR004450 Threonine synthase-like THITH_10735 7dde3cf57803fdaebd499e542f31c465 169 Pfam PF02674 Colicin V production protein 4 144 2.3E-37 T 13-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 THITH_17075 10490ef31097e05c32584bec0f6380cf 117 Pfam PF01022 Bacterial regulatory protein, arsR family 41 85 2.2E-12 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THITH_17075 10490ef31097e05c32584bec0f6380cf 117 SUPERFAMILY SSF46785 21 115 6.45E-26 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_17075 10490ef31097e05c32584bec0f6380cf 117 Gene3D G3DSA:1.10.10.10 17 115 1.9E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_17075 10490ef31097e05c32584bec0f6380cf 117 SMART SM00418 34 112 1.3E-24 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THITH_17075 10490ef31097e05c32584bec0f6380cf 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 66 8.5E-14 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THITH_17075 10490ef31097e05c32584bec0f6380cf 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 83 98 8.5E-14 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THITH_17075 10490ef31097e05c32584bec0f6380cf 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 68 83 8.5E-14 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THITH_17075 10490ef31097e05c32584bec0f6380cf 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 8.5E-14 T 13-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 THITH_00135 3563c01a3e295bb0900c941c16fc66a7 512 Pfam PF00437 Type II/IV secretion system protein 139 404 2.1E-87 T 13-10-2018 IPR001482 Type II/IV secretion system protein THITH_00135 3563c01a3e295bb0900c941c16fc66a7 512 Gene3D G3DSA:3.30.450.90 102 237 1.7E-51 T 13-10-2018 THITH_00135 3563c01a3e295bb0900c941c16fc66a7 512 SUPERFAMILY SSF160246 30 89 1.12E-7 T 13-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily THITH_00135 3563c01a3e295bb0900c941c16fc66a7 512 TIGRFAM TIGR02533 type_II_gspE: type II secretion system protein E 30 509 8.6E-212 T 13-10-2018 IPR013369 Type II secretion system GspE GO:0005524|GO:0008565|GO:0015627|GO:0015628 THITH_00135 3563c01a3e295bb0900c941c16fc66a7 512 Gene3D G3DSA:3.40.50.300 238 512 4.1E-118 T 13-10-2018 THITH_00135 3563c01a3e295bb0900c941c16fc66a7 512 SUPERFAMILY SSF52540 122 509 5.68E-101 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00135 3563c01a3e295bb0900c941c16fc66a7 512 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 332 346 - T 13-10-2018 IPR001482 Type II/IV secretion system protein THITH_00135 3563c01a3e295bb0900c941c16fc66a7 512 SMART SM00382 265 391 1.3E-5 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_16505 2c15e36d218cc6f5c9d0beb8f805753b 466 Gene3D G3DSA:3.30.70.20 204 286 3.8E-5 T 13-10-2018 THITH_16505 2c15e36d218cc6f5c9d0beb8f805753b 466 Pfam PF12801 4Fe-4S binding domain 79 121 3.4E-7 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_16505 2c15e36d218cc6f5c9d0beb8f805753b 466 Pfam PF12801 4Fe-4S binding domain 151 167 520.0 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_16505 2c15e36d218cc6f5c9d0beb8f805753b 466 SUPERFAMILY SSF54862 89 325 1.88E-28 T 13-10-2018 THITH_16505 2c15e36d218cc6f5c9d0beb8f805753b 466 Gene3D G3DSA:2.60.40.10 347 461 3.0E-11 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_16505 2c15e36d218cc6f5c9d0beb8f805753b 466 TIGRFAM TIGR02745 ccoG_rdxA_fixG: cytochrome c oxidase accessory protein CcoG 21 447 1.9E-138 T 13-10-2018 IPR014116 Cytochrome c oxidase cbb3 type, accessory protein FixG GO:0016021|GO:0055114 THITH_16505 2c15e36d218cc6f5c9d0beb8f805753b 466 Pfam PF11614 IG-like fold at C-terminal of FixG, putative oxidoreductase 345 450 1.1E-18 T 13-10-2018 IPR032879 FixG, C-terminal immunoglobulin-like domain THITH_16505 2c15e36d218cc6f5c9d0beb8f805753b 466 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 263 274 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_16505 2c15e36d218cc6f5c9d0beb8f805753b 466 Pfam PF13746 4Fe-4S dicluster domain 203 316 7.1E-53 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_14815 d8074dc39093e0aca7d749261287d170 300 Gene3D G3DSA:1.10.8.10 1 86 5.3E-20 T 13-10-2018 THITH_14815 d8074dc39093e0aca7d749261287d170 300 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 25 273 2.9E-81 T 13-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 THITH_14815 d8074dc39093e0aca7d749261287d170 300 SUPERFAMILY SSF53335 3 274 1.19E-53 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_14815 d8074dc39093e0aca7d749261287d170 300 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 3 277 41.358 T 13-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 THITH_14815 d8074dc39093e0aca7d749261287d170 300 Pfam PF05175 Methyltransferase small domain 98 192 3.0E-11 T 13-10-2018 IPR007848 Methyltransferase small domain GO:0008168 THITH_14815 d8074dc39093e0aca7d749261287d170 300 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 9 275 1.5E-63 T 13-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 THITH_14815 d8074dc39093e0aca7d749261287d170 300 Gene3D G3DSA:3.40.50.150 89 277 1.1E-54 T 13-10-2018 THITH_14815 d8074dc39093e0aca7d749261287d170 300 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 182 188 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THITH_12040 34d030a0a41a6482f10054c4bf42e744 477 SUPERFAMILY SSF52540 1 196 2.57E-42 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_12040 34d030a0a41a6482f10054c4bf42e744 477 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 13 188 4.6E-14 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THITH_12040 34d030a0a41a6482f10054c4bf42e744 477 Gene3D G3DSA:3.40.50.300 3 189 2.6E-28 T 13-10-2018 THITH_12040 34d030a0a41a6482f10054c4bf42e744 477 Gene3D G3DSA:3.40.50.880 244 464 1.0E-10 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_12040 34d030a0a41a6482f10054c4bf42e744 477 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 1 448 37.414 T 13-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 THITH_12040 34d030a0a41a6482f10054c4bf42e744 477 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 5 457 1.7E-123 T 13-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 THITH_12040 34d030a0a41a6482f10054c4bf42e744 477 SUPERFAMILY SSF52317 244 460 1.87E-34 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_12040 34d030a0a41a6482f10054c4bf42e744 477 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 246 446 9.7E-34 T 13-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 THITH_04380 d547a67bf8e579ae8304c623fb8e5e0c 194 Pfam PF14697 4Fe-4S dicluster domain 103 157 1.1E-18 T 13-10-2018 THITH_04380 d547a67bf8e579ae8304c623fb8e5e0c 194 Pfam PF04060 Putative Fe-S cluster 41 73 4.9E-15 T 13-10-2018 IPR007202 4Fe-4S domain GO:0051536 THITH_04380 d547a67bf8e579ae8304c623fb8e5e0c 194 Gene3D G3DSA:1.10.15.40 35 81 2.0E-9 T 13-10-2018 THITH_04380 d547a67bf8e579ae8304c623fb8e5e0c 194 TIGRFAM TIGR01944 rnfB: electron transport complex, RnfABCDGE type, B subunit 2 178 6.6E-80 T 13-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 THITH_04380 d547a67bf8e579ae8304c623fb8e5e0c 194 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 110 121 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_04380 d547a67bf8e579ae8304c623fb8e5e0c 194 SUPERFAMILY SSF54862 35 169 3.49E-31 T 13-10-2018 THITH_04380 d547a67bf8e579ae8304c623fb8e5e0c 194 Gene3D G3DSA:3.30.70.20 82 172 8.9E-23 T 13-10-2018 THITH_04380 d547a67bf8e579ae8304c623fb8e5e0c 194 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 140 151 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_04380 d547a67bf8e579ae8304c623fb8e5e0c 194 Hamap MF_00463 Ion-translocating oxidoreductase complex subunit B [rsxB]. 1 162 25.006 T 13-10-2018 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB GO:0009055|GO:0051536 THITH_04380 d547a67bf8e579ae8304c623fb8e5e0c 194 PIRSF PIRSF005784 1 182 1.0E-84 T 13-10-2018 IPR016463 Electron transport complex, RnfB/RsxB, Proteobacteria GO:0005886|GO:0022900|GO:0051536 THITH_12215 7a04028631d3f240e2b7924987158e47 114 Gene3D G3DSA:3.30.428.10 1 114 5.4E-41 T 13-10-2018 IPR036265 HIT-like superfamily THITH_12215 7a04028631d3f240e2b7924987158e47 114 ProSitePatterns PS00892 HIT domain signature. 87 105 - T 13-10-2018 IPR019808 Histidine triad, conserved site THITH_12215 7a04028631d3f240e2b7924987158e47 114 Pfam PF01230 HIT domain 13 108 1.3E-27 T 13-10-2018 IPR001310 Histidine triad (HIT) protein THITH_12215 7a04028631d3f240e2b7924987158e47 114 SUPERFAMILY SSF54197 2 113 1.31E-38 T 13-10-2018 IPR036265 HIT-like superfamily THITH_12215 7a04028631d3f240e2b7924987158e47 114 PRINTS PR00332 Histidine triad family signature 5 21 7.0E-19 T 13-10-2018 IPR001310 Histidine triad (HIT) protein THITH_12215 7a04028631d3f240e2b7924987158e47 114 PRINTS PR00332 Histidine triad family signature 94 104 7.0E-19 T 13-10-2018 IPR001310 Histidine triad (HIT) protein THITH_12215 7a04028631d3f240e2b7924987158e47 114 PRINTS PR00332 Histidine triad family signature 26 44 7.0E-19 T 13-10-2018 IPR001310 Histidine triad (HIT) protein THITH_02875 9d379447a74f8de52b8583b6df292cd8 592 Gene3D G3DSA:3.30.1360.30 273 422 2.6E-192 T 13-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 THITH_02875 9d379447a74f8de52b8583b6df292cd8 592 SUPERFAMILY SSF50249 1 105 2.48E-32 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_02875 9d379447a74f8de52b8583b6df292cd8 592 SUPERFAMILY SSF55681 110 586 3.45E-111 T 13-10-2018 THITH_02875 9d379447a74f8de52b8583b6df292cd8 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 520 534 7.7E-25 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_02875 9d379447a74f8de52b8583b6df292cd8 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 221 7.7E-25 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_02875 9d379447a74f8de52b8583b6df292cd8 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 203 7.7E-25 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_02875 9d379447a74f8de52b8583b6df292cd8 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 476 492 7.7E-25 T 13-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_02875 9d379447a74f8de52b8583b6df292cd8 592 Gene3D G3DSA:2.40.50.140 1 106 4.5E-35 T 13-10-2018 THITH_02875 9d379447a74f8de52b8583b6df292cd8 592 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 560 3.3E-107 T 13-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 THITH_02875 9d379447a74f8de52b8583b6df292cd8 592 Gene3D G3DSA:3.30.930.10 117 584 2.6E-192 T 13-10-2018 THITH_02875 9d379447a74f8de52b8583b6df292cd8 592 Pfam PF01336 OB-fold nucleic acid binding domain 18 90 7.9E-19 T 13-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 THITH_02875 9d379447a74f8de52b8583b6df292cd8 592 SUPERFAMILY SSF55261 291 422 3.43E-42 T 13-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 THITH_02875 9d379447a74f8de52b8583b6df292cd8 592 Pfam PF02938 GAD domain 309 408 3.8E-27 T 13-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 THITH_02875 9d379447a74f8de52b8583b6df292cd8 592 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 1 586 34.032 T 13-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 THITH_02875 9d379447a74f8de52b8583b6df292cd8 592 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 1 584 2.6E-239 T 13-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 THITH_08220 be8a279960d5ae6af9662c99fbed73b4 255 Gene3D G3DSA:1.10.4030.30 79 212 8.1E-26 T 13-10-2018 THITH_08220 be8a279960d5ae6af9662c99fbed73b4 255 Pfam PF00639 PPIC-type PPIASE domain 104 198 6.6E-19 T 13-10-2018 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type GO:0003755 THITH_08220 be8a279960d5ae6af9662c99fbed73b4 255 Gene3D G3DSA:3.10.50.40 98 201 8.1E-26 T 13-10-2018 THITH_08220 be8a279960d5ae6af9662c99fbed73b4 255 SUPERFAMILY SSF54534 90 197 1.18E-23 T 13-10-2018 THITH_08220 be8a279960d5ae6af9662c99fbed73b4 255 SUPERFAMILY SSF109998 2 122 5.1E-7 T 13-10-2018 IPR027304 Trigger factor/SurA domain superfamily THITH_04440 79863099e630a762e8e2747c0f4b05d4 115 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 111 1.2E-24 T 13-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like THITH_08335 d347156d5b7c7ef36f94197d99036239 273 Pfam PF04364 DNA polymerase III chi subunit, HolC 106 265 7.0E-6 T 13-10-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 THITH_08335 d347156d5b7c7ef36f94197d99036239 273 SUPERFAMILY SSF52540 17 262 1.27E-24 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_08335 d347156d5b7c7ef36f94197d99036239 273 Gene3D G3DSA:3.40.50.300 95 273 2.7E-29 T 13-10-2018 THITH_08335 d347156d5b7c7ef36f94197d99036239 273 Gene3D G3DSA:3.40.50.300 1 76 6.6E-12 T 13-10-2018 THITH_08335 d347156d5b7c7ef36f94197d99036239 273 Pfam PF00271 Helicase conserved C-terminal domain 127 227 2.3E-5 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_08335 d347156d5b7c7ef36f94197d99036239 273 Pfam PF04851 Type III restriction enzyme, res subunit 15 53 3.4E-8 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THITH_00835 44731d8d02a749134256b4774168e38c 162 Pfam PF16694 Cytochrome P460 32 158 1.1E-30 T 13-10-2018 IPR032033 Cytochrome P460 THITH_00835 44731d8d02a749134256b4774168e38c 162 Gene3D G3DSA:3.50.70.20 26 162 5.8E-25 T 13-10-2018 IPR038142 Cytochrome P460 superfamily THITH_12470 957f2f4a4f5629a21071d3b08ceef02e 219 Hamap MF_01681 Enolase-phosphatase E1 [mtnC]. 1 217 39.732 T 13-10-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 THITH_12470 957f2f4a4f5629a21071d3b08ceef02e 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 108 121 4.0E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_12470 957f2f4a4f5629a21071d3b08ceef02e 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 158 178 4.0E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_12470 957f2f4a4f5629a21071d3b08ceef02e 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 185 198 4.0E-6 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_12470 957f2f4a4f5629a21071d3b08ceef02e 219 TIGRFAM TIGR01691 enolase-ppase: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 1 216 4.4E-82 T 13-10-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 THITH_12470 957f2f4a4f5629a21071d3b08ceef02e 219 Gene3D G3DSA:3.40.50.1000 1 209 6.4E-72 T 13-10-2018 IPR023214 HAD superfamily THITH_12470 957f2f4a4f5629a21071d3b08ceef02e 219 Gene3D G3DSA:1.10.720.60 12 92 6.4E-72 T 13-10-2018 THITH_12470 957f2f4a4f5629a21071d3b08ceef02e 219 SUPERFAMILY SSF56784 1 215 6.0E-59 T 13-10-2018 IPR036412 HAD-like superfamily THITH_06325 034495477b499579960f5fc93257b5f7 409 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 75 86 3.2E-19 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THITH_06325 034495477b499579960f5fc93257b5f7 409 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 131 148 3.2E-19 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THITH_06325 034495477b499579960f5fc93257b5f7 409 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 158 171 3.2E-19 T 13-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 THITH_06325 034495477b499579960f5fc93257b5f7 409 SMART SM00936 298 388 1.6E-26 T 13-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THITH_06325 034495477b499579960f5fc93257b5f7 409 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 298 387 3.6E-18 T 13-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THITH_06325 034495477b499579960f5fc93257b5f7 409 SUPERFAMILY SSF69189 298 390 8.04E-20 T 13-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THITH_06325 034495477b499579960f5fc93257b5f7 409 Gene3D G3DSA:2.60.410.10 298 388 1.3E-24 T 13-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THITH_06325 034495477b499579960f5fc93257b5f7 409 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 41 271 1.3E-80 T 13-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 THITH_06325 034495477b499579960f5fc93257b5f7 409 Gene3D G3DSA:3.40.710.10 37 296 2.2E-88 T 13-10-2018 THITH_06325 034495477b499579960f5fc93257b5f7 409 SUPERFAMILY SSF56601 2 298 4.97E-84 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like THITH_11380 73b3e9a789d9bc2729126009c85d4736 271 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_11380 73b3e9a789d9bc2729126009c85d4736 271 Pfam PF00005 ABC transporter 35 163 3.4E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_11380 73b3e9a789d9bc2729126009c85d4736 271 SMART SM00382 44 212 1.5E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_11380 73b3e9a789d9bc2729126009c85d4736 271 Gene3D G3DSA:3.40.50.300 18 238 6.5E-56 T 13-10-2018 THITH_11380 73b3e9a789d9bc2729126009c85d4736 271 SUPERFAMILY SSF52540 16 230 8.62E-53 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_12500 07cba2fe7ec23bbc86ec514bb89435a6 633 SUPERFAMILY SSF53448 1 232 1.35E-42 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_12500 07cba2fe7ec23bbc86ec514bb89435a6 633 Gene3D G3DSA:3.40.50.2000 421 628 1.8E-27 T 13-10-2018 THITH_12500 07cba2fe7ec23bbc86ec514bb89435a6 633 Gene3D G3DSA:3.90.550.10 1 234 1.7E-42 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_12500 07cba2fe7ec23bbc86ec514bb89435a6 633 SUPERFAMILY SSF53756 291 629 4.49E-33 T 13-10-2018 THITH_12500 07cba2fe7ec23bbc86ec514bb89435a6 633 Pfam PF00534 Glycosyl transferases group 1 508 611 1.2E-13 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 THITH_12500 07cba2fe7ec23bbc86ec514bb89435a6 633 Gene3D G3DSA:3.40.50.2000 445 615 1.8E-27 T 13-10-2018 THITH_12500 07cba2fe7ec23bbc86ec514bb89435a6 633 Pfam PF00535 Glycosyl transferase family 2 2 130 3.1E-22 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THITH_02050 2cb230a6d9eb6096e81f80b6397364fa 296 Pfam PF12727 PBP superfamily domain 86 269 1.0E-40 T 13-10-2018 IPR024370 PBP domain THITH_02050 2cb230a6d9eb6096e81f80b6397364fa 296 SUPERFAMILY SSF46955 9 57 5.13E-5 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily THITH_02050 2cb230a6d9eb6096e81f80b6397364fa 296 Pfam PF12728 Helix-turn-helix domain 9 58 7.4E-14 T 13-10-2018 THITH_02050 2cb230a6d9eb6096e81f80b6397364fa 296 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 10 55 1.2E-10 T 13-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 THITH_02050 2cb230a6d9eb6096e81f80b6397364fa 296 SUPERFAMILY SSF53850 98 284 2.92E-7 T 13-10-2018 THITH_06240 0caf9c6e2e6b7723ed8b16b88ea77042 342 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 39 338 5.8E-108 T 13-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 THITH_06240 0caf9c6e2e6b7723ed8b16b88ea77042 342 SUPERFAMILY SSF46589 14 99 1.52E-20 T 13-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 THITH_06240 0caf9c6e2e6b7723ed8b16b88ea77042 342 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 8 338 50.319 T 13-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 THITH_06240 0caf9c6e2e6b7723ed8b16b88ea77042 342 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 21 87 3.1E-24 T 13-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 THITH_06240 0caf9c6e2e6b7723ed8b16b88ea77042 342 Pfam PF01409 tRNA synthetases class II core domain (F) 92 338 2.2E-108 T 13-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 THITH_06240 0caf9c6e2e6b7723ed8b16b88ea77042 342 Gene3D G3DSA:3.30.930.10 8 341 5.1E-122 T 13-10-2018 THITH_06240 0caf9c6e2e6b7723ed8b16b88ea77042 342 SUPERFAMILY SSF55681 92 338 8.29E-82 T 13-10-2018 THITH_12155 699a0d6c53f699694d98abb87c6c15ad 77 Pfam PF05768 Glutaredoxin-like domain (DUF836) 1 73 4.3E-16 T 13-10-2018 IPR008554 Glutaredoxin-like THITH_12155 699a0d6c53f699694d98abb87c6c15ad 77 SUPERFAMILY SSF52833 1 75 5.74E-16 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_12155 699a0d6c53f699694d98abb87c6c15ad 77 Gene3D G3DSA:3.40.30.10 1 73 3.4E-19 T 13-10-2018 THITH_07230 be0ab2f597a05e3bfcde9993f8787f6e 1038 Gene3D G3DSA:3.40.50.300 257 437 3.3E-47 T 13-10-2018 THITH_07230 be0ab2f597a05e3bfcde9993f8787f6e 1038 Gene3D G3DSA:3.90.1570.50 105 256 4.3E-19 T 13-10-2018 THITH_07230 be0ab2f597a05e3bfcde9993f8787f6e 1038 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 28 203 1.9E-26 T 13-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 THITH_07230 be0ab2f597a05e3bfcde9993f8787f6e 1038 Gene3D G3DSA:3.40.50.300 440 688 1.3E-38 T 13-10-2018 THITH_07230 be0ab2f597a05e3bfcde9993f8787f6e 1038 Pfam PF04851 Type III restriction enzyme, res subunit 256 417 3.0E-14 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THITH_07230 be0ab2f597a05e3bfcde9993f8787f6e 1038 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 28 685 1.3E-138 T 13-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 THITH_07230 be0ab2f597a05e3bfcde9993f8787f6e 1038 SMART SM00487 254 454 3.7E-9 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_07230 be0ab2f597a05e3bfcde9993f8787f6e 1038 SUPERFAMILY SSF52540 234 454 2.16E-24 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01375 62a830460a2b943b9f8a6205a4b993f1 243 Pfam PF13247 4Fe-4S dicluster domain 66 167 2.0E-24 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_01375 62a830460a2b943b9f8a6205a4b993f1 243 Gene3D G3DSA:3.30.70.20 1 228 9.6E-69 T 13-10-2018 THITH_01375 62a830460a2b943b9f8a6205a4b993f1 243 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 106 117 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_01375 62a830460a2b943b9f8a6205a4b993f1 243 Pfam PF12800 4Fe-4S binding domain 11 24 0.032 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_01375 62a830460a2b943b9f8a6205a4b993f1 243 SUPERFAMILY SSF54862 1 209 2.51E-71 T 13-10-2018 THITH_16915 dea0a5373e6f87a174c5b9af1edf98f7 124 SUPERFAMILY SSF75169 1 124 1.8E-7 T 13-10-2018 IPR027396 DsrEFH-like THITH_16915 dea0a5373e6f87a174c5b9af1edf98f7 124 Pfam PF02635 DsrE/DsrF-like family 1 124 5.4E-7 T 13-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THITH_10375 aecfea56e0fdc0d9dfe3e9bf3b857179 157 SUPERFAMILY SSF143243 4 149 1.05E-45 T 13-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10375 aecfea56e0fdc0d9dfe3e9bf3b857179 157 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 77 137 3.0E-15 T 13-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10375 aecfea56e0fdc0d9dfe3e9bf3b857179 157 Gene3D G3DSA:3.30.460.80 1 127 1.0E-33 T 13-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10375 aecfea56e0fdc0d9dfe3e9bf3b857179 157 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 30 148 9.0E-40 T 13-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_02660 079fcb3a57c1c6240a1abad119700569 426 Pfam PF03471 Transporter associated domain 341 414 1.2E-15 T 13-10-2018 IPR005170 Transporter-associated domain THITH_02660 079fcb3a57c1c6240a1abad119700569 426 Pfam PF00571 CBS domain 204 258 2.4E-4 T 13-10-2018 IPR000644 CBS domain THITH_02660 079fcb3a57c1c6240a1abad119700569 426 Pfam PF00571 CBS domain 294 325 3.4E-4 T 13-10-2018 IPR000644 CBS domain THITH_02660 079fcb3a57c1c6240a1abad119700569 426 Gene3D G3DSA:3.10.580.10 186 338 6.7E-43 T 13-10-2018 THITH_02660 079fcb3a57c1c6240a1abad119700569 426 Gene3D G3DSA:3.30.465.10 339 415 1.9E-24 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 THITH_02660 079fcb3a57c1c6240a1abad119700569 426 SUPERFAMILY SSF54631 200 343 4.51E-27 T 13-10-2018 THITH_02660 079fcb3a57c1c6240a1abad119700569 426 SMART SM01091 340 417 4.4E-19 T 13-10-2018 IPR005170 Transporter-associated domain THITH_02660 079fcb3a57c1c6240a1abad119700569 426 SUPERFAMILY SSF56176 338 423 6.54E-19 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 THITH_02660 079fcb3a57c1c6240a1abad119700569 426 Pfam PF01595 Domain of unknown function DUF21 13 181 1.6E-42 T 13-10-2018 IPR002550 CNNM, transmembrane domain THITH_11000 b51ca65c2554ee1faba46b410ddf5da0 265 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 17 73 5.2E-5 T 13-10-2018 IPR013589 Bacterial transglutaminase-like, N-terminal THITH_11000 b51ca65c2554ee1faba46b410ddf5da0 265 Pfam PF01841 Transglutaminase-like superfamily 117 217 1.2E-24 T 13-10-2018 IPR002931 Transglutaminase-like THITH_11000 b51ca65c2554ee1faba46b410ddf5da0 265 SMART SM00460 159 219 3.1E-18 T 13-10-2018 IPR002931 Transglutaminase-like THITH_11000 b51ca65c2554ee1faba46b410ddf5da0 265 Gene3D G3DSA:3.10.620.30 78 239 3.4E-69 T 13-10-2018 THITH_11000 b51ca65c2554ee1faba46b410ddf5da0 265 Gene3D G3DSA:2.60.40.2250 8 246 3.4E-69 T 13-10-2018 THITH_11000 b51ca65c2554ee1faba46b410ddf5da0 265 SUPERFAMILY SSF54001 19 245 4.21E-36 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily THITH_07390 3c8ca84ae80544ab87d8e5085af47bb9 947 SUPERFAMILY SSF48695 213 418 1.82E-18 T 13-10-2018 IPR036280 Multiheme cytochrome superfamily THITH_07390 3c8ca84ae80544ab87d8e5085af47bb9 947 Gene3D G3DSA:1.25.40.10 791 878 1.4E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_07390 3c8ca84ae80544ab87d8e5085af47bb9 947 Pfam PF13435 Cytochrome c554 and c-prime 214 301 2.7E-4 T 13-10-2018 IPR023155 Cytochrome c-552/4 THITH_07390 3c8ca84ae80544ab87d8e5085af47bb9 947 Gene3D G3DSA:1.25.40.10 670 784 4.0E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_07390 3c8ca84ae80544ab87d8e5085af47bb9 947 SUPERFAMILY SSF48452 685 873 5.88E-7 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_03960 8ea5f69e945602fe1d7dc92a22e824e2 1836 Gene3D G3DSA:3.40.50.300 322 489 1.0E-18 T 13-10-2018 THITH_03960 8ea5f69e945602fe1d7dc92a22e824e2 1836 Gene3D G3DSA:3.40.50.300 1171 1352 2.6E-18 T 13-10-2018 THITH_03960 8ea5f69e945602fe1d7dc92a22e824e2 1836 SUPERFAMILY SSF52540 1316 1550 8.35E-5 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_03960 8ea5f69e945602fe1d7dc92a22e824e2 1836 SUPERFAMILY SSF52540 340 1405 9.82E-28 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_03960 8ea5f69e945602fe1d7dc92a22e824e2 1836 Pfam PF13086 AAA domain 1295 1335 1.9E-8 T 13-10-2018 THITH_03960 8ea5f69e945602fe1d7dc92a22e824e2 1836 Pfam PF13087 AAA domain 1369 1550 5.5E-11 T 13-10-2018 THITH_03960 8ea5f69e945602fe1d7dc92a22e824e2 1836 SUPERFAMILY SSF52980 1591 1695 2.63E-15 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_03960 8ea5f69e945602fe1d7dc92a22e824e2 1836 Pfam PF13604 AAA domain 340 402 1.9E-6 T 13-10-2018 THITH_03960 8ea5f69e945602fe1d7dc92a22e824e2 1836 Gene3D G3DSA:3.40.960.10 1591 1698 1.2E-16 T 13-10-2018 THITH_03960 8ea5f69e945602fe1d7dc92a22e824e2 1836 Gene3D G3DSA:3.40.50.300 1377 1568 9.8E-25 T 13-10-2018 THITH_03960 8ea5f69e945602fe1d7dc92a22e824e2 1836 Pfam PF13195 Protein of unknown function (DUF4011) 21 227 1.7E-41 T 13-10-2018 IPR025103 Protein of unknown function DUF4011 THITH_08750 e95e9c5797f424f360b346abe0a74d09 313 Pfam PF00698 Acyl transferase domain 8 283 1.3E-32 T 13-10-2018 IPR014043 Acyl transferase THITH_08750 e95e9c5797f424f360b346abe0a74d09 313 Gene3D G3DSA:3.40.366.10 8 287 8.9E-93 T 13-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 THITH_08750 e95e9c5797f424f360b346abe0a74d09 313 PIRSF PIRSF000446 2 312 9.3E-104 T 13-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 THITH_08750 e95e9c5797f424f360b346abe0a74d09 313 SUPERFAMILY SSF52151 5 310 2.62E-73 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase THITH_08750 e95e9c5797f424f360b346abe0a74d09 313 Gene3D G3DSA:3.30.70.250 126 198 8.9E-93 T 13-10-2018 THITH_08750 e95e9c5797f424f360b346abe0a74d09 313 SUPERFAMILY SSF55048 131 198 1.57E-15 T 13-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding THITH_08750 e95e9c5797f424f360b346abe0a74d09 313 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 8 313 5.7E-34 T 13-10-2018 IPR020801 Polyketide synthase, acyl transferase domain THITH_08750 e95e9c5797f424f360b346abe0a74d09 313 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 4 292 3.8E-102 T 13-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 THITH_13615 57b631ffc489d8df378b2e0e03b604db 126 SUPERFAMILY SSF50692 1 116 1.62E-44 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily THITH_13615 57b631ffc489d8df378b2e0e03b604db 126 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 125 5.2E-44 T 13-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 THITH_13615 57b631ffc489d8df378b2e0e03b604db 126 PIRSF PIRSF006246 1 125 5.2E-46 T 13-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 THITH_13615 57b631ffc489d8df378b2e0e03b604db 126 Pfam PF02261 Aspartate decarboxylase 1 114 1.0E-45 T 13-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 THITH_13615 57b631ffc489d8df378b2e0e03b604db 126 Gene3D G3DSA:2.40.40.20 1 126 1.7E-50 T 13-10-2018 THITH_13615 57b631ffc489d8df378b2e0e03b604db 126 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 126 65.96 T 13-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 THITH_13615 57b631ffc489d8df378b2e0e03b604db 126 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 123 1.0E-40 T 13-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 THITH_05380 ac1fa556a9ed6533010ce253efc3458e 427 Pfam PF03861 ANTAR domain 367 417 2.6E-18 T 13-10-2018 IPR005561 ANTAR domain GO:0003723 THITH_05380 ac1fa556a9ed6533010ce253efc3458e 427 SMART SM01012 364 419 5.6E-23 T 13-10-2018 IPR005561 ANTAR domain GO:0003723 THITH_05380 ac1fa556a9ed6533010ce253efc3458e 427 Pfam PF08376 Nitrate and nitrite sensing 28 273 4.0E-45 T 13-10-2018 IPR013587 Nitrate/nitrite sensing protein THITH_05380 ac1fa556a9ed6533010ce253efc3458e 427 SUPERFAMILY SSF52172 347 417 3.63E-14 T 13-10-2018 IPR011006 CheY-like superfamily THITH_05380 ac1fa556a9ed6533010ce253efc3458e 427 Gene3D G3DSA:1.10.10.10 367 424 3.7E-18 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_16185 cb70d153f5a1336fedf744123cb4f48c 422 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 9 123 8.3E-28 T 13-10-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI THITH_16185 cb70d153f5a1336fedf744123cb4f48c 422 SUPERFAMILY SSF48452 153 276 3.2E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_16185 cb70d153f5a1336fedf744123cb4f48c 422 Pfam PF14559 Tetratricopeptide repeat 152 208 4.4E-7 T 13-10-2018 THITH_16185 cb70d153f5a1336fedf744123cb4f48c 422 Gene3D G3DSA:1.25.40.10 207 292 4.1E-15 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_16185 cb70d153f5a1336fedf744123cb4f48c 422 Gene3D G3DSA:1.25.40.10 132 206 1.2E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_15750 2071da1ed249d9d57b745c9bc546296f 262 ProDom PD587589 PHOSPHODIESTERASE ICC METALLOPHOSPHOESTERASE CYCLIC REGULATOR LACZ AMP HYDROLASE 3'5'-CYCLIC-NUCLEOTIDE EXPRESSION 199 254 2.0E-12 T 13-10-2018 IPR013622 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA, C-terminal KEGG: 00230+3.1.4.53 THITH_15750 2071da1ed249d9d57b745c9bc546296f 262 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 8 254 37.118 T 13-10-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 THITH_15750 2071da1ed249d9d57b745c9bc546296f 262 SUPERFAMILY SSF56300 9 258 4.29E-58 T 13-10-2018 THITH_15750 2071da1ed249d9d57b745c9bc546296f 262 Gene3D G3DSA:3.60.21.10 1 258 8.9E-68 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like THITH_15750 2071da1ed249d9d57b745c9bc546296f 262 Pfam PF00149 Calcineurin-like phosphoesterase 9 200 1.3E-13 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THITH_07490 ee0a3989bb808388872577b78046dd9b 186 Gene3D G3DSA:2.60.40.1880 53 186 2.5E-29 T 13-10-2018 IPR038696 Invasion protein B superfamily THITH_07490 ee0a3989bb808388872577b78046dd9b 186 Pfam PF06776 Invasion associated locus B (IalB) protein 55 183 1.9E-26 T 13-10-2018 IPR010642 Invasion protein B THITH_03845 c7af8bf333f46dbc346ab6f296170497 476 Pfam PF13091 PLD-like domain 129 271 1.0E-15 T 13-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THITH_03845 c7af8bf333f46dbc346ab6f296170497 476 Pfam PF13091 PLD-like domain 317 434 2.5E-23 T 13-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 THITH_03845 c7af8bf333f46dbc346ab6f296170497 476 SMART SM00155 211 238 1.4E-4 T 13-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 THITH_03845 c7af8bf333f46dbc346ab6f296170497 476 SMART SM00155 389 416 0.022 T 13-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 THITH_03845 c7af8bf333f46dbc346ab6f296170497 476 Pfam PF13396 Phospholipase_D-nuclease N-terminal 19 59 5.9E-8 T 13-10-2018 IPR027379 Cardiolipin synthase N-terminal THITH_03845 c7af8bf333f46dbc346ab6f296170497 476 PIRSF PIRSF000850 260 282 740.0 T 13-10-2018 THITH_03845 c7af8bf333f46dbc346ab6f296170497 476 PIRSF PIRSF000850 306 367 0.2 T 13-10-2018 THITH_03845 c7af8bf333f46dbc346ab6f296170497 476 PIRSF PIRSF000850 371 443 0.013 T 13-10-2018 THITH_03845 c7af8bf333f46dbc346ab6f296170497 476 PIRSF PIRSF000850 106 186 0.93 T 13-10-2018 THITH_03845 c7af8bf333f46dbc346ab6f296170497 476 Gene3D G3DSA:3.30.870.10 301 466 3.7E-22 T 13-10-2018 THITH_03845 c7af8bf333f46dbc346ab6f296170497 476 SUPERFAMILY SSF56024 105 308 1.91E-48 T 13-10-2018 THITH_03845 c7af8bf333f46dbc346ab6f296170497 476 SUPERFAMILY SSF56024 287 462 1.73E-36 T 13-10-2018 THITH_03845 c7af8bf333f46dbc346ab6f296170497 476 Gene3D G3DSA:3.30.870.10 107 293 1.1E-41 T 13-10-2018 THITH_09715 bb5010b26dbaaef1f2c1c9d968faa3b9 432 PIRSF PIRSF001369 40 432 3.1E-165 T 13-10-2018 IPR024176 Citrate synthase, bacterial-type THITH_09715 bb5010b26dbaaef1f2c1c9d968faa3b9 432 ProSitePatterns PS00480 Citrate synthase signature. 306 318 - T 13-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 THITH_09715 bb5010b26dbaaef1f2c1c9d968faa3b9 432 Gene3D G3DSA:1.10.230.10 270 380 2.6E-145 T 13-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain THITH_09715 bb5010b26dbaaef1f2c1c9d968faa3b9 432 PRINTS PR00143 Citrate synthase signature 221 236 5.8E-56 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 THITH_09715 bb5010b26dbaaef1f2c1c9d968faa3b9 432 PRINTS PR00143 Citrate synthase signature 383 397 5.8E-56 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 THITH_09715 bb5010b26dbaaef1f2c1c9d968faa3b9 432 PRINTS PR00143 Citrate synthase signature 243 271 5.8E-56 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 THITH_09715 bb5010b26dbaaef1f2c1c9d968faa3b9 432 PRINTS PR00143 Citrate synthase signature 299 319 5.8E-56 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 THITH_09715 bb5010b26dbaaef1f2c1c9d968faa3b9 432 PRINTS PR00143 Citrate synthase signature 167 180 5.8E-56 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 THITH_09715 bb5010b26dbaaef1f2c1c9d968faa3b9 432 PRINTS PR00143 Citrate synthase signature 363 379 5.8E-56 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 THITH_09715 bb5010b26dbaaef1f2c1c9d968faa3b9 432 Gene3D G3DSA:1.10.580.10 59 415 2.6E-145 T 13-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 THITH_09715 bb5010b26dbaaef1f2c1c9d968faa3b9 432 Gene3D G3DSA:2.20.28.60 3 52 7.4E-21 T 13-10-2018 THITH_09715 bb5010b26dbaaef1f2c1c9d968faa3b9 432 SUPERFAMILY SSF48256 8 432 1.96E-163 T 13-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 THITH_09715 bb5010b26dbaaef1f2c1c9d968faa3b9 432 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 15 426 8.5E-219 T 13-10-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 THITH_09715 bb5010b26dbaaef1f2c1c9d968faa3b9 432 Pfam PF00285 Citrate synthase, C-terminal domain 50 415 3.4E-133 T 13-10-2018 IPR002020 Citrate synthase GO:0046912 THITH_04565 ae950256a69521b7edf343c2b1a001f6 120 SUPERFAMILY SSF143100 13 69 1.96E-18 T 13-10-2018 IPR035069 TTHA1013/TTHA0281-like THITH_04565 ae950256a69521b7edf343c2b1a001f6 120 SUPERFAMILY SSF47598 72 113 1.51E-10 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 THITH_04565 ae950256a69521b7edf343c2b1a001f6 120 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 14 70 7.2E-12 T 13-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system THITH_04565 ae950256a69521b7edf343c2b1a001f6 120 Gene3D G3DSA:1.10.1220.10 76 118 3.1E-8 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THITH_04565 ae950256a69521b7edf343c2b1a001f6 120 Pfam PF05534 HicB family 72 104 3.6E-10 T 13-10-2018 IPR008651 Uncharacterised protein family HicB THITH_04565 ae950256a69521b7edf343c2b1a001f6 120 Gene3D G3DSA:3.30.160.250 7 75 2.2E-17 T 13-10-2018 THITH_02430 7f1c3de472704ef1ffcc633257f29cdc 482 TIGRFAM TIGR02199 rfaE_dom_II: bifunctional protein RfaE, domain II 331 472 5.1E-62 T 13-10-2018 IPR011914 RfaE bifunctional protein, domain II GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 THITH_02430 7f1c3de472704ef1ffcc633257f29cdc 482 Gene3D G3DSA:3.40.50.620 324 476 1.7E-36 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_02430 7f1c3de472704ef1ffcc633257f29cdc 482 Pfam PF00294 pfkB family carbohydrate kinase 13 303 1.2E-50 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB THITH_02430 7f1c3de472704ef1ffcc633257f29cdc 482 Hamap MF_01603 Bifunctional protein HldE [hldE]. 4 474 43.528 T 13-10-2018 IPR023030 Bifunctional protein HldE GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 THITH_02430 7f1c3de472704ef1ffcc633257f29cdc 482 SUPERFAMILY SSF53613 11 311 1.56E-63 T 13-10-2018 IPR029056 Ribokinase-like THITH_02430 7f1c3de472704ef1ffcc633257f29cdc 482 Gene3D G3DSA:3.40.1190.20 3 309 5.6E-110 T 13-10-2018 IPR029056 Ribokinase-like THITH_02430 7f1c3de472704ef1ffcc633257f29cdc 482 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 342 408 7.9E-15 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THITH_02430 7f1c3de472704ef1ffcc633257f29cdc 482 TIGRFAM TIGR02198 rfaE_dom_I: bifunctional protein RfaE, domain I 6 312 2.2E-121 T 13-10-2018 IPR011913 RfaE bifunctional protein, domain I GO:0005975|GO:0016773|GO:0016779 KEGG: 00540+2.7.7.70+2.7.1.167 THITH_02430 7f1c3de472704ef1ffcc633257f29cdc 482 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 51 74 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 THITH_02430 7f1c3de472704ef1ffcc633257f29cdc 482 SUPERFAMILY SSF52374 341 471 2.62E-22 T 13-10-2018 THITH_02430 7f1c3de472704ef1ffcc633257f29cdc 482 Pfam PF01467 Cytidylyltransferase-like 345 435 1.6E-13 T 13-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 THITH_01785 1db11fff24e11d318618b55d6b3a0b31 703 Pfam PF07715 TonB-dependent Receptor Plug Domain 59 170 1.4E-19 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain THITH_01785 1db11fff24e11d318618b55d6b3a0b31 703 Gene3D G3DSA:2.170.130.10 46 175 1.7E-23 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily THITH_01785 1db11fff24e11d318618b55d6b3a0b31 703 Pfam PF00593 TonB dependent receptor 282 699 6.1E-42 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel THITH_01785 1db11fff24e11d318618b55d6b3a0b31 703 SUPERFAMILY SSF56935 34 699 2.29E-93 T 13-10-2018 THITH_01785 1db11fff24e11d318618b55d6b3a0b31 703 Gene3D G3DSA:2.40.170.20 200 700 4.2E-68 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily THITH_12085 030012d1c984de8b287d465f55e61c06 585 ProSitePatterns PS00211 ABC transporters family signature. 483 497 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_12085 030012d1c984de8b287d465f55e61c06 585 Pfam PF00005 ABC transporter 362 511 9.3E-34 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_12085 030012d1c984de8b287d465f55e61c06 585 Pfam PF00664 ABC transporter transmembrane region 30 300 1.2E-51 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 THITH_12085 030012d1c984de8b287d465f55e61c06 585 SMART SM00382 371 557 6.7E-19 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_12085 030012d1c984de8b287d465f55e61c06 585 SUPERFAMILY SSF90123 17 330 4.32E-71 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THITH_12085 030012d1c984de8b287d465f55e61c06 585 TIGRFAM TIGR02203 MsbA_lipidA: lipid A export permease/ATP-binding protein MsbA 16 584 2.6E-232 T 13-10-2018 IPR011917 ABC transporter, lipid A export, MsbA GO:0005524|GO:0016021|GO:0034040 THITH_12085 030012d1c984de8b287d465f55e61c06 585 Gene3D G3DSA:1.20.1560.10 3 332 4.0E-79 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THITH_12085 030012d1c984de8b287d465f55e61c06 585 Gene3D G3DSA:3.40.50.300 333 583 9.3E-94 T 13-10-2018 THITH_12085 030012d1c984de8b287d465f55e61c06 585 SUPERFAMILY SSF52540 335 582 4.33E-93 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_10000 54ffc49d78daa1d593322d45e6cccba0 495 Gene3D G3DSA:3.30.420.150 110 290 8.5E-85 T 13-10-2018 THITH_10000 54ffc49d78daa1d593322d45e6cccba0 495 SUPERFAMILY SSF53067 6 126 1.85E-35 T 13-10-2018 THITH_10000 54ffc49d78daa1d593322d45e6cccba0 495 SUPERFAMILY SSF109604 308 493 3.82E-51 T 13-10-2018 THITH_10000 54ffc49d78daa1d593322d45e6cccba0 495 Gene3D G3DSA:3.30.420.40 7 297 8.5E-85 T 13-10-2018 THITH_10000 54ffc49d78daa1d593322d45e6cccba0 495 PIRSF PIRSF001267 2 495 2.3E-188 T 13-10-2018 IPR030673 Pyrophosphatase, GppA/Ppx-type KEGG: 00230+3.6.1.40 THITH_10000 54ffc49d78daa1d593322d45e6cccba0 495 SUPERFAMILY SSF53067 131 306 6.83E-43 T 13-10-2018 THITH_10000 54ffc49d78daa1d593322d45e6cccba0 495 Pfam PF02541 Ppx/GppA phosphatase family 20 301 3.2E-72 T 13-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 THITH_10000 54ffc49d78daa1d593322d45e6cccba0 495 Gene3D G3DSA:1.10.3210.10 305 494 3.0E-60 T 13-10-2018 THITH_15910 380495695d987199d5e1240a6506f01a 167 Gene3D G3DSA:3.40.50.7700 1 166 3.2E-71 T 13-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 THITH_15910 380495695d987199d5e1240a6506f01a 167 Pfam PF00731 AIR carboxylase 8 155 2.9E-62 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 THITH_15910 380495695d987199d5e1240a6506f01a 167 PIRSF PIRSF001338 3 163 2.8E-64 T 13-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 THITH_15910 380495695d987199d5e1240a6506f01a 167 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 8 161 31.688 T 13-10-2018 IPR033747 Class I PurE THITH_15910 380495695d987199d5e1240a6506f01a 167 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 8 160 3.6E-63 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 THITH_15910 380495695d987199d5e1240a6506f01a 167 SMART SM01001 6 157 3.0E-99 T 13-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 THITH_15910 380495695d987199d5e1240a6506f01a 167 SUPERFAMILY SSF52255 7 161 1.83E-64 T 13-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 THITH_08870 634ec4f77768c6dff490f5365bafbfbf 222 Gene3D G3DSA:1.10.760.10 33 115 5.2E-24 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_08870 634ec4f77768c6dff490f5365bafbfbf 222 Gene3D G3DSA:1.10.760.10 126 217 3.8E-22 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_08870 634ec4f77768c6dff490f5365bafbfbf 222 SUPERFAMILY SSF46626 126 217 3.2E-19 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_08870 634ec4f77768c6dff490f5365bafbfbf 222 SUPERFAMILY SSF46626 48 116 3.1E-19 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_08870 634ec4f77768c6dff490f5365bafbfbf 222 PIRSF PIRSF000005 8 219 1.9E-56 T 13-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 THITH_08870 634ec4f77768c6dff490f5365bafbfbf 222 Pfam PF00034 Cytochrome c 148 217 1.9E-7 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_08870 634ec4f77768c6dff490f5365bafbfbf 222 Pfam PF00034 Cytochrome c 48 112 7.3E-6 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_09595 077fd0b1d2c35055aa90e78a60997666 134 Pfam PF14489 QueF-like protein 40 117 1.1E-31 T 13-10-2018 IPR029500 NADPH-dependent 7-cyano-7-deazaguanine reductase QueF GO:0008616|GO:0033739 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 THITH_09595 077fd0b1d2c35055aa90e78a60997666 134 TIGRFAM TIGR03139 QueF-II: 7-cyano-7-deazaguanine reductase 7 116 3.1E-52 T 13-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 THITH_09595 077fd0b1d2c35055aa90e78a60997666 134 Gene3D G3DSA:3.30.1130.10 3 128 7.7E-44 T 13-10-2018 THITH_09595 077fd0b1d2c35055aa90e78a60997666 134 Hamap MF_00818 NADPH-dependent 7-cyano-7-deazaguanine reductase [queF]. 1 134 49.907 T 13-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 THITH_09595 077fd0b1d2c35055aa90e78a60997666 134 SUPERFAMILY SSF55620 5 111 2.52E-26 T 13-10-2018 THITH_09595 077fd0b1d2c35055aa90e78a60997666 134 PIRSF PIRSF027377 2 124 3.2E-53 T 13-10-2018 IPR016856 NADPH-dependent 7-cyano-7-deazaguanine reductase, QueF type 1 GO:0005737|GO:0008616|GO:0046857|GO:0055114 KEGG: 00790+1.7.1.13|MetaCyc: PWY-6700 THITH_05305 40f018f744c11572d2954c7f46076228 531 Pfam PF02690 Na+/Pi-cotransporter 168 250 3.2E-7 T 13-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 THITH_05305 40f018f744c11572d2954c7f46076228 531 Pfam PF02690 Na+/Pi-cotransporter 12 147 3.1E-27 T 13-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 THITH_00430 9920d26c293966e7b74ea27711971771 159 SUPERFAMILY SSF103247 32 157 1.83E-21 T 13-10-2018 IPR035923 TT1751-like domain superfamily THITH_00430 9920d26c293966e7b74ea27711971771 159 Gene3D G3DSA:3.30.310.70 30 159 1.6E-19 T 13-10-2018 IPR035923 TT1751-like domain superfamily THITH_00430 9920d26c293966e7b74ea27711971771 159 Pfam PF03625 Domain of unknown function DUF302 74 127 2.3E-10 T 13-10-2018 IPR005180 Domain of unknown function DUF302 THITH_14390 ca2e78f3221e6a09383d1b476b436a47 402 Gene3D G3DSA:1.20.81.30 255 366 4.3E-32 T 13-10-2018 THITH_14390 ca2e78f3221e6a09383d1b476b436a47 402 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 163 191 - T 13-10-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 THITH_14390 ca2e78f3221e6a09383d1b476b436a47 402 Gene3D G3DSA:1.20.81.30 53 170 3.3E-30 T 13-10-2018 THITH_14390 ca2e78f3221e6a09383d1b476b436a47 402 Pfam PF00482 Type II secretion system (T2SS), protein F 68 191 4.3E-34 T 13-10-2018 IPR018076 Type II secretion system F domain THITH_14390 ca2e78f3221e6a09383d1b476b436a47 402 Pfam PF00482 Type II secretion system (T2SS), protein F 272 394 1.4E-33 T 13-10-2018 IPR018076 Type II secretion system F domain THITH_14390 ca2e78f3221e6a09383d1b476b436a47 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 367 381 2.2E-17 T 13-10-2018 IPR003004 GspF/PilC family THITH_14390 ca2e78f3221e6a09383d1b476b436a47 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 64 76 2.2E-17 T 13-10-2018 IPR003004 GspF/PilC family THITH_14390 ca2e78f3221e6a09383d1b476b436a47 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 163 191 2.2E-17 T 13-10-2018 IPR003004 GspF/PilC family THITH_14390 ca2e78f3221e6a09383d1b476b436a47 402 PRINTS PR00812 Bacterial general secretion pathway protein F signature 383 402 2.2E-17 T 13-10-2018 IPR003004 GspF/PilC family THITH_04830 4d2cc2b5c18a032a45cec175ad4aec02 127 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 14 121 2.4E-31 T 13-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein THITH_04830 4d2cc2b5c18a032a45cec175ad4aec02 127 SUPERFAMILY SSF64076 1 122 3.92E-36 T 13-10-2018 IPR036748 MTH938-like superfamily THITH_04830 4d2cc2b5c18a032a45cec175ad4aec02 127 Gene3D G3DSA:3.40.1230.10 2 124 4.7E-37 T 13-10-2018 IPR036748 MTH938-like superfamily THITH_14350 f578c369667a3b9361a976ed83e08aec 177 SUPERFAMILY SSF82679 4 114 1.09E-39 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THITH_14350 f578c369667a3b9361a976ed83e08aec 177 SMART SM00738 2 111 8.5E-48 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THITH_14350 f578c369667a3b9361a976ed83e08aec 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 176 6.2E-70 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 THITH_14350 f578c369667a3b9361a976ed83e08aec 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 25.3 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 THITH_14350 f578c369667a3b9361a976ed83e08aec 177 SUPERFAMILY SSF50104 121 176 4.86E-20 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily THITH_14350 f578c369667a3b9361a976ed83e08aec 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 3.6E-19 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 THITH_14350 f578c369667a3b9361a976ed83e08aec 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 3.6E-19 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 THITH_14350 f578c369667a3b9361a976ed83e08aec 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 3.6E-19 T 13-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 THITH_14350 f578c369667a3b9361a976ed83e08aec 177 SMART SM00739 123 150 1.2E-5 T 13-10-2018 IPR005824 KOW THITH_14350 f578c369667a3b9361a976ed83e08aec 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 13-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site THITH_14350 f578c369667a3b9361a976ed83e08aec 177 Pfam PF02357 Transcription termination factor nusG 4 108 1.8E-26 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THITH_14350 f578c369667a3b9361a976ed83e08aec 177 Gene3D G3DSA:2.30.30.30 118 176 4.7E-26 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 THITH_14350 f578c369667a3b9361a976ed83e08aec 177 Gene3D G3DSA:3.30.70.940 1 117 8.9E-47 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THITH_14350 f578c369667a3b9361a976ed83e08aec 177 Pfam PF00467 KOW motif 126 156 4.8E-7 T 13-10-2018 IPR005824 KOW THITH_07930 665a0d325cc6528debac840329ded4bf 870 Gene3D G3DSA:2.120.10.90 531 840 1.7E-117 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal THITH_07930 665a0d325cc6528debac840329ded4bf 870 SMART SM00434 11 499 2.2E-294 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THITH_07930 665a0d325cc6528debac840329ded4bf 870 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 32 501 1.1E-152 T 13-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 THITH_07930 665a0d325cc6528debac840329ded4bf 870 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 1 840 24.327 T 13-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 THITH_07930 665a0d325cc6528debac840329ded4bf 870 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 8 839 0.0 T 13-10-2018 THITH_07930 665a0d325cc6528debac840329ded4bf 870 Gene3D G3DSA:3.90.199.10 33 521 8.8E-228 T 13-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 THITH_07930 665a0d325cc6528debac840329ded4bf 870 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 588 637 9.5E-10 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THITH_07930 665a0d325cc6528debac840329ded4bf 870 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 538 584 6.5E-9 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THITH_07930 665a0d325cc6528debac840329ded4bf 870 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 744 786 2.3E-8 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THITH_07930 665a0d325cc6528debac840329ded4bf 870 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 646 688 2.1E-8 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THITH_07930 665a0d325cc6528debac840329ded4bf 870 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 792 838 2.5E-13 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THITH_07930 665a0d325cc6528debac840329ded4bf 870 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 692 738 2.1E-12 T 13-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 THITH_07930 665a0d325cc6528debac840329ded4bf 870 SUPERFAMILY SSF56719 30 521 5.1E-181 T 13-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 THITH_07930 665a0d325cc6528debac840329ded4bf 870 Gene3D G3DSA:1.10.268.10 370 493 8.8E-228 T 13-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 THITH_07930 665a0d325cc6528debac840329ded4bf 870 Gene3D G3DSA:3.30.1360.40 236 333 8.8E-228 T 13-10-2018 THITH_07930 665a0d325cc6528debac840329ded4bf 870 SUPERFAMILY SSF101904 533 851 1.7E-105 T 13-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal THITH_06185 fe67db2e309530c437fbde1850fcdb1e 320 Pfam PF12345 Protein of unknown function (DUF3641) 182 318 1.4E-56 T 13-10-2018 IPR024521 Domain of unknown function DUF3641 THITH_06185 fe67db2e309530c437fbde1850fcdb1e 320 TIGRFAM TIGR04167 rSAM_SeCys: radical SAM/Cys-rich domain protein 16 319 3.3E-137 T 13-10-2018 IPR026351 Radical SAM/Cys-rich domain protein THITH_06185 fe67db2e309530c437fbde1850fcdb1e 320 Gene3D G3DSA:3.20.20.70 17 285 1.8E-17 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_06185 fe67db2e309530c437fbde1850fcdb1e 320 SUPERFAMILY SSF102114 21 316 1.7E-34 T 13-10-2018 THITH_04210 e0e92e80b1dd2d434cac8c6954acb292 253 SUPERFAMILY SSF56112 27 210 1.6E-9 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily THITH_07100 d3f4a75f8465cbe97fcebeb84bdd5979 364 Gene3D G3DSA:3.30.390.50 261 358 5.8E-17 T 13-10-2018 THITH_07100 d3f4a75f8465cbe97fcebeb84bdd5979 364 Gene3D G3DSA:3.30.930.10 4 255 4.5E-44 T 13-10-2018 THITH_07100 d3f4a75f8465cbe97fcebeb84bdd5979 364 SUPERFAMILY SSF55681 1 247 7.46E-55 T 13-10-2018 THITH_09205 d5017e884dbb9b3957fe667fa39fefab 830 SMART SM00267 394 567 3.6E-6 T 13-10-2018 IPR000160 GGDEF domain THITH_09205 d5017e884dbb9b3957fe667fa39fefab 830 SMART SM00448 273 387 0.0089 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_09205 d5017e884dbb9b3957fe667fa39fefab 830 SMART SM00052 579 825 3.1E-43 T 13-10-2018 IPR001633 EAL domain THITH_09205 d5017e884dbb9b3957fe667fa39fefab 830 SUPERFAMILY SSF141868 587 820 7.85E-52 T 13-10-2018 IPR035919 EAL domain superfamily THITH_09205 d5017e884dbb9b3957fe667fa39fefab 830 Gene3D G3DSA:3.30.70.270 391 566 1.8E-12 T 13-10-2018 THITH_09205 d5017e884dbb9b3957fe667fa39fefab 830 Gene3D G3DSA:3.40.50.12740 272 372 9.9E-8 T 13-10-2018 THITH_09205 d5017e884dbb9b3957fe667fa39fefab 830 Pfam PF00563 EAL domain 587 820 5.4E-52 T 13-10-2018 IPR001633 EAL domain THITH_09205 d5017e884dbb9b3957fe667fa39fefab 830 Pfam PF00990 Diguanylate cyclase, GGDEF domain 406 560 1.9E-4 T 13-10-2018 IPR000160 GGDEF domain THITH_09205 d5017e884dbb9b3957fe667fa39fefab 830 SUPERFAMILY SSF52172 271 398 2.85E-11 T 13-10-2018 IPR011006 CheY-like superfamily THITH_09205 d5017e884dbb9b3957fe667fa39fefab 830 Gene3D G3DSA:3.20.20.450 578 826 7.0E-57 T 13-10-2018 IPR035919 EAL domain superfamily THITH_09205 d5017e884dbb9b3957fe667fa39fefab 830 SUPERFAMILY SSF55073 411 565 2.98E-8 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_11645 5b7037501701efca8b0c9724a9b6661f 671 SUPERFAMILY SSF51621 124 618 2.06E-58 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 THITH_11645 5b7037501701efca8b0c9724a9b6661f 671 Gene3D G3DSA:3.20.20.60 446 607 9.0E-56 T 13-10-2018 THITH_11645 5b7037501701efca8b0c9724a9b6661f 671 Gene3D G3DSA:2.40.33.10 366 445 9.0E-56 T 13-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THITH_11645 5b7037501701efca8b0c9724a9b6661f 671 Gene3D G3DSA:2.40.33.10 208 318 3.3E-19 T 13-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THITH_11645 5b7037501701efca8b0c9724a9b6661f 671 SUPERFAMILY SSF50800 363 445 2.97E-9 T 13-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily THITH_11645 5b7037501701efca8b0c9724a9b6661f 671 Pfam PF00224 Pyruvate kinase, barrel domain 141 225 3.1E-8 T 13-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THITH_11645 5b7037501701efca8b0c9724a9b6661f 671 Pfam PF00224 Pyruvate kinase, barrel domain 377 609 4.3E-36 T 13-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 THITH_11645 5b7037501701efca8b0c9724a9b6661f 671 Gene3D G3DSA:3.20.20.60 142 207 3.3E-19 T 13-10-2018 THITH_09220 bc33496b0a467022048795ea360d43e6 1375 TIGRFAM TIGR02680 TIGR02680: TIGR02680 family protein 11 1346 0.0 T 13-10-2018 IPR013496 Conserved hypothetical protein CHP02680 THITH_09220 bc33496b0a467022048795ea360d43e6 1375 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1216 1297 1.4E-19 T 13-10-2018 THITH_09220 bc33496b0a467022048795ea360d43e6 1375 SUPERFAMILY SSF52540 24 1299 4.94E-5 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00520 8be6bbd13613654dacbeec584e1c8b52 321 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 19 302 1.2E-105 T 13-10-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007059|GO:0015074|GO:0051301 THITH_00520 8be6bbd13613654dacbeec584e1c8b52 321 Gene3D G3DSA:1.10.443.10 117 294 1.2E-58 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 THITH_00520 8be6bbd13613654dacbeec584e1c8b52 321 Gene3D G3DSA:1.10.150.130 14 105 7.8E-18 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal THITH_00520 8be6bbd13613654dacbeec584e1c8b52 321 Pfam PF00589 Phage integrase family 118 286 4.5E-45 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THITH_00520 8be6bbd13613654dacbeec584e1c8b52 321 SUPERFAMILY SSF56349 19 292 2.59E-54 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THITH_00520 8be6bbd13613654dacbeec584e1c8b52 321 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 15 300 58.605 T 13-10-2018 IPR023009 Tyrosine recombinase XerC/XerD THITH_00520 8be6bbd13613654dacbeec584e1c8b52 321 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 19 96 2.8E-18 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THITH_16925 4421fa8e525f6171723aa604abed989c 216 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 10 188 7.8E-73 T 13-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 THITH_16925 4421fa8e525f6171723aa604abed989c 216 SUPERFAMILY SSF52540 9 193 5.78E-67 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16925 4421fa8e525f6171723aa604abed989c 216 Gene3D G3DSA:3.30.63.10 41 100 1.1E-67 T 13-10-2018 THITH_16925 4421fa8e525f6171723aa604abed989c 216 Pfam PF00625 Guanylate kinase 11 189 1.8E-54 T 13-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit THITH_16925 4421fa8e525f6171723aa604abed989c 216 Hamap MF_00328 Guanylate kinase [gmk]. 8 191 35.645 T 13-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 THITH_16925 4421fa8e525f6171723aa604abed989c 216 ProSitePatterns PS00856 Guanylate kinase-like signature. 44 61 - T 13-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 THITH_16925 4421fa8e525f6171723aa604abed989c 216 SMART SM00072 9 191 6.3E-67 T 13-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit THITH_16925 4421fa8e525f6171723aa604abed989c 216 Gene3D G3DSA:3.40.50.300 14 187 1.1E-67 T 13-10-2018 THITH_11915 5c046ebfcfef0e02bbc5f050c8cfdd93 263 Pfam PF13432 Tetratricopeptide repeat 50 113 6.9E-6 T 13-10-2018 THITH_11915 5c046ebfcfef0e02bbc5f050c8cfdd93 263 SUPERFAMILY SSF48452 37 193 6.07E-25 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_11915 5c046ebfcfef0e02bbc5f050c8cfdd93 263 Gene3D G3DSA:1.25.40.10 38 258 7.9E-48 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_11915 5c046ebfcfef0e02bbc5f050c8cfdd93 263 TIGRFAM TIGR02521 type_IV_pilW: type IV pilus biogenesis/stability protein PilW 20 246 2.4E-53 T 13-10-2018 IPR013360 Pilus biogenesis/stability type IV, PilW THITH_11915 5c046ebfcfef0e02bbc5f050c8cfdd93 263 SMART SM00028 112 145 22.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_11915 5c046ebfcfef0e02bbc5f050c8cfdd93 263 SMART SM00028 78 111 0.0046 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_11915 5c046ebfcfef0e02bbc5f050c8cfdd93 263 SMART SM00028 148 181 0.12 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_11915 5c046ebfcfef0e02bbc5f050c8cfdd93 263 SMART SM00028 44 77 0.1 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_11915 5c046ebfcfef0e02bbc5f050c8cfdd93 263 Pfam PF13424 Tetratricopeptide repeat 114 179 1.3E-10 T 13-10-2018 THITH_05725 782d78d77c0961a97e9a25a5203daf36 143 SUPERFAMILY SSF47413 82 141 2.03E-5 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 THITH_05725 782d78d77c0961a97e9a25a5203daf36 143 Gene3D G3DSA:3.30.160.250 4 77 2.5E-12 T 13-10-2018 THITH_05725 782d78d77c0961a97e9a25a5203daf36 143 SUPERFAMILY SSF143100 4 64 1.83E-12 T 13-10-2018 IPR035069 TTHA1013/TTHA0281-like THITH_08265 7876f7f8129047ce0ca7fac9e8b04e62 368 Pfam PF13676 TIR domain 34 141 6.7E-8 T 13-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THITH_08265 7876f7f8129047ce0ca7fac9e8b04e62 368 Gene3D G3DSA:3.40.50.10140 4 157 7.2E-15 T 13-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily THITH_08265 7876f7f8129047ce0ca7fac9e8b04e62 368 SUPERFAMILY SSF52200 4 112 4.84E-10 T 13-10-2018 IPR035897 Toll/interleukin-1 receptor homology (TIR) domain superfamily THITH_08265 7876f7f8129047ce0ca7fac9e8b04e62 368 SMART SM00255 9 188 0.0028 T 13-10-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 THITH_05220 e4241d7e62865088550f46b5d9bea0d6 99 Gene3D G3DSA:3.30.70.240 1 65 9.0E-18 T 13-10-2018 THITH_05220 e4241d7e62865088550f46b5d9bea0d6 99 SUPERFAMILY SSF143430 1 75 1.03E-14 T 13-10-2018 THITH_05220 e4241d7e62865088550f46b5d9bea0d6 99 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 80 1.6E-9 T 13-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THITH_05220 e4241d7e62865088550f46b5d9bea0d6 99 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 90 10.736 T 13-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 THITH_05220 e4241d7e62865088550f46b5d9bea0d6 99 Pfam PF09827 CRISPR associated protein Cas2 1 67 1.5E-13 T 13-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 THITH_06815 71939270fdbaa4128d058604f4b06b61 384 Pfam PF07995 Glucose / Sorbosone dehydrogenase 44 374 1.6E-113 T 13-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase THITH_06815 71939270fdbaa4128d058604f4b06b61 384 Gene3D G3DSA:2.120.10.30 30 383 1.6E-106 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like THITH_06815 71939270fdbaa4128d058604f4b06b61 384 SUPERFAMILY SSF50952 37 382 7.32E-48 T 13-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 THITH_16275 d3548437e8b224c5c35cd7f99b734565 187 Pfam PF03843 Outer membrane lipoprotein Slp family 22 173 1.5E-45 T 13-10-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 THITH_16275 d3548437e8b224c5c35cd7f99b734565 187 PIRSF PIRSF004982 9 187 4.1E-49 T 13-10-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 THITH_16275 d3548437e8b224c5c35cd7f99b734565 187 TIGRFAM TIGR00752 slp: outer membrane lipoprotein, Slp family 16 184 6.7E-28 T 13-10-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 THITH_08925 65e26ae4e31db7d037b5e6da0d61d8ad 294 Gene3D G3DSA:3.40.30.10 196 292 7.5E-26 T 13-10-2018 THITH_08925 65e26ae4e31db7d037b5e6da0d61d8ad 294 SMART SM00756 25 156 3.6E-16 T 13-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 THITH_08925 65e26ae4e31db7d037b5e6da0d61d8ad 294 Gene3D G3DSA:1.20.1440.130 18 189 5.4E-32 T 13-10-2018 IPR038354 VKOR domain superfamily Reactome: R-HSA-6806664 THITH_08925 65e26ae4e31db7d037b5e6da0d61d8ad 294 Pfam PF07884 Vitamin K epoxide reductase family 30 152 1.8E-20 T 13-10-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 THITH_08925 65e26ae4e31db7d037b5e6da0d61d8ad 294 SUPERFAMILY SSF52833 213 272 1.83E-5 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_14275 d70febdb2a9a7801199cb648a6a9fda1 273 SUPERFAMILY SSF50249 2 124 7.2E-45 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_14275 d70febdb2a9a7801199cb648a6a9fda1 273 PIRSF PIRSF002158 10 273 1.1E-97 T 13-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14275 d70febdb2a9a7801199cb648a6a9fda1 273 Gene3D G3DSA:2.40.50.140 1 114 2.4E-46 T 13-10-2018 THITH_14275 d70febdb2a9a7801199cb648a6a9fda1 273 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 249 3.3E-54 T 13-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 THITH_14275 d70febdb2a9a7801199cb648a6a9fda1 273 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 272 45.746 T 13-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 THITH_14275 d70febdb2a9a7801199cb648a6a9fda1 273 SUPERFAMILY SSF50104 126 269 1.62E-58 T 13-10-2018 IPR008991 Translation protein SH3-like domain superfamily THITH_14275 d70febdb2a9a7801199cb648a6a9fda1 273 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 116 4.5E-32 T 13-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14275 d70febdb2a9a7801199cb648a6a9fda1 273 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 4 273 1.4E-124 T 13-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 THITH_14275 d70febdb2a9a7801199cb648a6a9fda1 273 Gene3D G3DSA:4.10.950.10 196 273 8.5E-36 T 13-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14275 d70febdb2a9a7801199cb648a6a9fda1 273 Gene3D G3DSA:2.30.30.30 115 195 1.7E-30 T 13-10-2018 IPR014722 Ribosomal protein L2, domain 2 THITH_14275 d70febdb2a9a7801199cb648a6a9fda1 273 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 13-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14275 d70febdb2a9a7801199cb648a6a9fda1 273 SMART SM01383 42 118 2.4E-44 T 13-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14275 d70febdb2a9a7801199cb648a6a9fda1 273 SMART SM01382 124 251 5.9E-86 T 13-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 THITH_11755 9a80bbdcdb1278e117ada9e4431a9862 84 SUPERFAMILY SSF143120 4 65 2.22E-11 T 13-10-2018 IPR036165 YefM-like superfamily THITH_11755 9a80bbdcdb1278e117ada9e4431a9862 84 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 5 62 2.4E-11 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THITH_11755 9a80bbdcdb1278e117ada9e4431a9862 84 Gene3D G3DSA:3.40.1620.10 7 52 2.1E-8 T 13-10-2018 THITH_11755 9a80bbdcdb1278e117ada9e4431a9862 84 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 8 53 8.6E-8 T 13-10-2018 THITH_14255 11f614a6125d7c206e9338093e18df28 137 SUPERFAMILY SSF54686 1 134 7.72E-56 T 13-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 THITH_14255 11f614a6125d7c206e9338093e18df28 137 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 13-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14255 11f614a6125d7c206e9338093e18df28 137 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 38.295 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14255 11f614a6125d7c206e9338093e18df28 137 Gene3D G3DSA:3.90.1170.10 1 137 7.7E-57 T 13-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 THITH_14255 11f614a6125d7c206e9338093e18df28 137 Pfam PF00252 Ribosomal protein L16p/L10e 4 131 3.6E-49 T 13-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 THITH_14255 11f614a6125d7c206e9338093e18df28 137 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.0E-59 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14255 11f614a6125d7c206e9338093e18df28 137 PRINTS PR00060 Ribosomal protein L16 signature 42 53 9.6E-40 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14255 11f614a6125d7c206e9338093e18df28 137 PRINTS PR00060 Ribosomal protein L16 signature 88 117 9.6E-40 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14255 11f614a6125d7c206e9338093e18df28 137 PRINTS PR00060 Ribosomal protein L16 signature 58 87 9.6E-40 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14255 11f614a6125d7c206e9338093e18df28 137 PRINTS PR00060 Ribosomal protein L16 signature 24 36 9.6E-40 T 13-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14255 11f614a6125d7c206e9338093e18df28 137 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 13-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_13525 1618046a6300345d7039c5046ac8cfb2 414 Pfam PF00994 Probable molybdopterin binding domain 190 324 2.1E-26 T 13-10-2018 IPR001453 MoaB/Mog domain THITH_13525 1618046a6300345d7039c5046ac8cfb2 414 Pfam PF03454 MoeA C-terminal region (domain IV) 339 410 1.2E-22 T 13-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_13525 1618046a6300345d7039c5046ac8cfb2 414 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 262 295 - T 13-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 THITH_13525 1618046a6300345d7039c5046ac8cfb2 414 SUPERFAMILY SSF63867 335 413 1.05E-23 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_13525 1618046a6300345d7039c5046ac8cfb2 414 Gene3D G3DSA:3.90.105.10 36 183 1.4E-141 T 13-10-2018 THITH_13525 1618046a6300345d7039c5046ac8cfb2 414 SUPERFAMILY SSF53218 186 330 1.57E-42 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily THITH_13525 1618046a6300345d7039c5046ac8cfb2 414 Gene3D G3DSA:3.40.980.10 184 335 1.4E-141 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily THITH_13525 1618046a6300345d7039c5046ac8cfb2 414 Gene3D G3DSA:2.170.190.11 59 150 1.4E-141 T 13-10-2018 THITH_13525 1618046a6300345d7039c5046ac8cfb2 414 SUPERFAMILY SSF63882 14 185 8.76E-53 T 13-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_13525 1618046a6300345d7039c5046ac8cfb2 414 SMART SM00852 189 326 5.8E-40 T 13-10-2018 IPR001453 MoaB/Mog domain THITH_13525 1618046a6300345d7039c5046ac8cfb2 414 Gene3D G3DSA:2.40.340.10 336 405 1.4E-141 T 13-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_13525 1618046a6300345d7039c5046ac8cfb2 414 Pfam PF03453 MoeA N-terminal region (domain I and II) 17 176 7.0E-44 T 13-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_13525 1618046a6300345d7039c5046ac8cfb2 414 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 186 322 2.0E-29 T 13-10-2018 IPR001453 MoaB/Mog domain THITH_14670 659a2881ac9fe98c3d332e44563fbcef 157 SUPERFAMILY SSF55804 1 147 5.89E-33 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 THITH_14670 659a2881ac9fe98c3d332e44563fbcef 157 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 56 72 - T 13-10-2018 IPR002178 PTS EIIA type-2 domain THITH_14670 659a2881ac9fe98c3d332e44563fbcef 157 Gene3D G3DSA:3.40.930.10 1 151 3.1E-41 T 13-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 THITH_14670 659a2881ac9fe98c3d332e44563fbcef 157 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 7 145 3.8E-31 T 13-10-2018 IPR002178 PTS EIIA type-2 domain THITH_08100 0b764c2eb23a29144e5ecfb79f2fa459 174 Gene3D G3DSA:3.30.1050.10 47 140 7.0E-9 T 13-10-2018 IPR036527 SCP2 sterol-binding domain superfamily THITH_08100 0b764c2eb23a29144e5ecfb79f2fa459 174 SUPERFAMILY SSF55718 48 143 4.24E-19 T 13-10-2018 IPR036527 SCP2 sterol-binding domain superfamily THITH_08100 0b764c2eb23a29144e5ecfb79f2fa459 174 Pfam PF02036 SCP-2 sterol transfer family 47 137 1.3E-17 T 13-10-2018 IPR003033 SCP2 sterol-binding domain THITH_12840 844ce327a7eb119b40b1b2db6d26fcfb 86 Pfam PF13937 Domain of unknown function (DUF4212) 8 84 4.4E-35 T 13-10-2018 IPR019886 Sodium symporter small subunit, predicted THITH_12840 844ce327a7eb119b40b1b2db6d26fcfb 86 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 9 85 1.2E-35 T 13-10-2018 IPR019886 Sodium symporter small subunit, predicted THITH_01930 6fe9f2f720a38b7c4771a716c27ba711 101 Gene3D G3DSA:1.10.260.40 5 101 2.8E-30 T 13-10-2018 THITH_01930 6fe9f2f720a38b7c4771a716c27ba711 101 Pfam PF01381 Helix-turn-helix 20 71 1.0E-8 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_01930 6fe9f2f720a38b7c4771a716c27ba711 101 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 8 86 1.9E-29 T 13-10-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 THITH_01930 6fe9f2f720a38b7c4771a716c27ba711 101 SMART SM00530 17 72 2.3E-7 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_01930 6fe9f2f720a38b7c4771a716c27ba711 101 SUPERFAMILY SSF47413 12 91 1.72E-22 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 THITH_17260 966946e5c10ef2d3f8f4b16a8acc107e 526 ProSitePatterns PS01303 BCCT family of transporters signature. 330 339 - T 13-10-2018 IPR018093 BCCT transporter, conserved site THITH_17260 966946e5c10ef2d3f8f4b16a8acc107e 526 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 27 513 5.0E-177 T 13-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 THITH_17260 966946e5c10ef2d3f8f4b16a8acc107e 526 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 66 513 3.7E-138 T 13-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 THITH_10305 d06ccd88955c47be9e0f90a684fc18a4 167 Gene3D G3DSA:3.40.630.30 9 151 6.1E-14 T 13-10-2018 THITH_10305 d06ccd88955c47be9e0f90a684fc18a4 167 Pfam PF00583 Acetyltransferase (GNAT) family 33 129 3.0E-7 T 13-10-2018 IPR000182 GNAT domain THITH_10305 d06ccd88955c47be9e0f90a684fc18a4 167 SUPERFAMILY SSF55729 15 146 6.8E-17 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_11250 b9fd8aeb5e2b8621822a8d99fa7b5429 101 SUPERFAMILY SSF81296 43 98 6.44E-14 T 13-10-2018 IPR014756 Immunoglobulin E-set THITH_11250 b9fd8aeb5e2b8621822a8d99fa7b5429 101 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 48 98 7.9E-10 T 13-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 THITH_11250 b9fd8aeb5e2b8621822a8d99fa7b5429 101 Gene3D G3DSA:2.60.40.10 29 101 1.9E-14 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_00910 c05ac355308b6695dab77a469e03fdc9 322 SUPERFAMILY SSF48576 8 321 1.73E-103 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily THITH_00910 c05ac355308b6695dab77a469e03fdc9 322 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site THITH_00910 c05ac355308b6695dab77a469e03fdc9 322 Gene3D G3DSA:1.10.600.10 1 322 3.1E-116 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily THITH_00910 c05ac355308b6695dab77a469e03fdc9 322 Pfam PF00348 Polyprenyl synthetase 31 267 7.7E-77 T 13-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 THITH_00910 c05ac355308b6695dab77a469e03fdc9 322 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site THITH_13890 f38ca2d77b5f095eb35c98e06cea390e 114 Pfam PF01909 Nucleotidyltransferase domain 15 66 1.3E-7 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THITH_13890 f38ca2d77b5f095eb35c98e06cea390e 114 SUPERFAMILY SSF81301 12 114 3.82E-14 T 13-10-2018 THITH_13890 f38ca2d77b5f095eb35c98e06cea390e 114 Gene3D G3DSA:3.30.460.10 2 107 7.4E-12 T 13-10-2018 THITH_08785 de42b81e3983297e35301334e37e3d90 209 ProDom PD037115 UPF0274 YCFC HI0638 METABOLISM UNCHARACTERIZED VV1342 PURINE INVOLVED SO2634 HFLD 10 196 4.0E-35 T 13-10-2018 THITH_08785 de42b81e3983297e35301334e37e3d90 209 Hamap MF_00695 High frequency lysogenization protein HflD [hflD]. 1 205 34.624 T 13-10-2018 IPR007451 High frequency lysogenization protein HflD THITH_08785 de42b81e3983297e35301334e37e3d90 209 Gene3D G3DSA:1.10.3890.10 2 209 5.1E-78 T 13-10-2018 IPR035932 HflD-like superfamily THITH_08785 de42b81e3983297e35301334e37e3d90 209 Pfam PF04356 Protein of unknown function (DUF489) 7 197 7.8E-74 T 13-10-2018 IPR007451 High frequency lysogenization protein HflD THITH_08785 de42b81e3983297e35301334e37e3d90 209 SUPERFAMILY SSF101322 6 207 4.58E-67 T 13-10-2018 IPR035932 HflD-like superfamily THITH_07960 03c79321bbc04d29e3e11e05283c4dee 435 ProSitePatterns PS00104 EPSP synthase signature 1. 90 104 - T 13-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 THITH_07960 03c79321bbc04d29e3e11e05283c4dee 435 Gene3D G3DSA:3.65.10.10 15 422 7.0E-150 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 THITH_07960 03c79321bbc04d29e3e11e05283c4dee 435 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 9 423 2.5E-113 T 13-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 THITH_07960 03c79321bbc04d29e3e11e05283c4dee 435 PIRSF PIRSF000505 2 434 9.2E-110 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 THITH_07960 03c79321bbc04d29e3e11e05283c4dee 435 SUPERFAMILY SSF55205 6 429 7.52E-126 T 13-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 THITH_07960 03c79321bbc04d29e3e11e05283c4dee 435 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 15 426 2.2E-119 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 THITH_07960 03c79321bbc04d29e3e11e05283c4dee 435 ProSitePatterns PS00885 EPSP synthase signature 2. 342 360 - T 13-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 THITH_07960 03c79321bbc04d29e3e11e05283c4dee 435 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 11 431 31.618 T 13-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 THITH_07960 03c79321bbc04d29e3e11e05283c4dee 435 Gene3D G3DSA:3.65.10.10 23 232 7.0E-150 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 THITH_04980 6e62b9ccb3356729df85dfe0d4a1c23b 401 Gene3D G3DSA:2.40.420.20 52 360 3.1E-70 T 13-10-2018 THITH_04980 6e62b9ccb3356729df85dfe0d4a1c23b 401 SUPERFAMILY SSF111369 59 305 3.4E-28 T 13-10-2018 THITH_04980 6e62b9ccb3356729df85dfe0d4a1c23b 401 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 65 300 1.6E-27 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THITH_04980 6e62b9ccb3356729df85dfe0d4a1c23b 401 Gene3D G3DSA:2.40.50.100 67 231 3.1E-70 T 13-10-2018 THITH_04980 6e62b9ccb3356729df85dfe0d4a1c23b 401 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 43 383 2.0E-58 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THITH_04980 6e62b9ccb3356729df85dfe0d4a1c23b 401 Gene3D G3DSA:2.40.30.170 56 307 3.1E-70 T 13-10-2018 THITH_04980 6e62b9ccb3356729df85dfe0d4a1c23b 401 Gene3D G3DSA:1.10.287.470 101 192 3.1E-70 T 13-10-2018 THITH_13605 be712a2bf37a78c6d8c3cde9300c55b3 484 Pfam PF00534 Glycosyl transferases group 1 287 440 9.2E-20 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 THITH_13605 be712a2bf37a78c6d8c3cde9300c55b3 484 Pfam PF08323 Starch synthase catalytic domain 2 234 4.0E-73 T 13-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 THITH_13605 be712a2bf37a78c6d8c3cde9300c55b3 484 Gene3D G3DSA:3.40.50.2000 3 476 1.4E-177 T 13-10-2018 THITH_13605 be712a2bf37a78c6d8c3cde9300c55b3 484 SUPERFAMILY SSF53756 3 480 4.19E-117 T 13-10-2018 THITH_13605 be712a2bf37a78c6d8c3cde9300c55b3 484 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 1 478 1.4E-165 T 13-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 THITH_13605 be712a2bf37a78c6d8c3cde9300c55b3 484 Gene3D G3DSA:3.40.50.2000 248 462 1.4E-177 T 13-10-2018 THITH_13605 be712a2bf37a78c6d8c3cde9300c55b3 484 Hamap MF_00484 Glycogen synthase [glgA]. 1 478 43.922 T 13-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 THITH_09855 048dd35ec09e6491950eac57c95be77b 323 Gene3D G3DSA:3.90.550.10 1 230 7.4E-40 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_09855 048dd35ec09e6491950eac57c95be77b 323 SUPERFAMILY SSF53448 3 255 1.07E-34 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_09855 048dd35ec09e6491950eac57c95be77b 323 Pfam PF00535 Glycosyl transferase family 2 7 166 1.1E-19 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THITH_12465 a992633f24e2a28198a3f9d75f6f9021 426 Pfam PF01593 Flavin containing amine oxidoreductase 18 271 1.2E-16 T 13-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 THITH_12465 a992633f24e2a28198a3f9d75f6f9021 426 SUPERFAMILY SSF51905 10 298 3.11E-39 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_12465 a992633f24e2a28198a3f9d75f6f9021 426 Gene3D G3DSA:3.50.50.60 2 424 2.9E-81 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_12465 a992633f24e2a28198a3f9d75f6f9021 426 PRINTS PR00419 Adrenodoxin reductase family signature 10 32 7.6E-5 T 13-10-2018 THITH_12465 a992633f24e2a28198a3f9d75f6f9021 426 PRINTS PR00419 Adrenodoxin reductase family signature 33 46 7.6E-5 T 13-10-2018 THITH_16970 3039452d2fbbbacb4112559ceb446633 262 Pfam PF13614 AAA domain 3 177 6.1E-56 T 13-10-2018 IPR025669 AAA domain THITH_16970 3039452d2fbbbacb4112559ceb446633 262 SUPERFAMILY SSF52540 3 252 5.57E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16970 3039452d2fbbbacb4112559ceb446633 262 Gene3D G3DSA:3.40.50.300 1 254 1.3E-75 T 13-10-2018 THITH_05770 6edad21dafb7c426238c04026d5ff90c 565 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 169 433 2.1E-101 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THITH_05770 6edad21dafb7c426238c04026d5ff90c 565 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 468 556 5.5E-17 T 13-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase THITH_05770 6edad21dafb7c426238c04026d5ff90c 565 SUPERFAMILY SSF53383 163 559 6.66E-109 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_05770 6edad21dafb7c426238c04026d5ff90c 565 Gene3D G3DSA:3.40.640.10 149 396 7.3E-93 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_01795 52a3497eff63658fdf515e67a9b072a3 155 Gene3D G3DSA:1.10.10.10 1 89 5.9E-32 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_01795 52a3497eff63658fdf515e67a9b072a3 155 Gene3D G3DSA:3.30.1490.190 90 148 9.8E-17 T 13-10-2018 THITH_01795 52a3497eff63658fdf515e67a9b072a3 155 Pfam PF01475 Ferric uptake regulator family 20 138 7.3E-15 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 THITH_01795 52a3497eff63658fdf515e67a9b072a3 155 SUPERFAMILY SSF46785 13 144 2.82E-31 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_07635 573e7acb418310416b2217854b3bee83 551 Pfam PF00512 His Kinase A (phospho-acceptor) domain 329 392 6.8E-10 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_07635 573e7acb418310416b2217854b3bee83 551 Gene3D G3DSA:1.10.287.130 304 391 1.0E-18 T 13-10-2018 THITH_07635 573e7acb418310416b2217854b3bee83 551 SUPERFAMILY SSF47384 325 392 1.51E-8 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_07635 573e7acb418310416b2217854b3bee83 551 SMART SM00388 328 396 1.7E-6 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_07635 573e7acb418310416b2217854b3bee83 551 SUPERFAMILY SSF55874 387 546 2.23E-39 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_07635 573e7acb418310416b2217854b3bee83 551 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 442 545 1.1E-20 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_07635 573e7acb418310416b2217854b3bee83 551 SMART SM00387 438 546 1.4E-29 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_07635 573e7acb418310416b2217854b3bee83 551 Pfam PF05231 MASE1 30 306 1.2E-19 T 13-10-2018 IPR007895 MASE1 THITH_07635 573e7acb418310416b2217854b3bee83 551 Gene3D G3DSA:3.30.565.10 396 550 8.0E-42 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_07635 573e7acb418310416b2217854b3bee83 551 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 524 1.3E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_07635 573e7acb418310416b2217854b3bee83 551 PRINTS PR00344 Bacterial sensor protein C-terminal signature 495 505 1.3E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_07635 573e7acb418310416b2217854b3bee83 551 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 543 1.3E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_07635 573e7acb418310416b2217854b3bee83 551 PRINTS PR00344 Bacterial sensor protein C-terminal signature 477 491 1.3E-14 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_07365 688522f88b596de739f706d8bed14c12 318 Gene3D G3DSA:3.30.2010.10 70 158 1.6E-20 T 13-10-2018 THITH_07365 688522f88b596de739f706d8bed14c12 318 Pfam PF01435 Peptidase family M48 76 279 2.0E-29 T 13-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 THITH_14510 304b64bd72308623cbe5fcafa14625cd 149 Pfam PF02381 MraZ protein, putative antitoxin-like 77 126 1.2E-18 T 13-10-2018 IPR020603 MraZ domain THITH_14510 304b64bd72308623cbe5fcafa14625cd 149 Pfam PF02381 MraZ protein, putative antitoxin-like 1 74 2.8E-18 T 13-10-2018 IPR020603 MraZ domain THITH_14510 304b64bd72308623cbe5fcafa14625cd 149 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 1 144 4.6E-47 T 13-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 THITH_14510 304b64bd72308623cbe5fcafa14625cd 149 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 124 4.0E-43 T 13-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 THITH_14510 304b64bd72308623cbe5fcafa14625cd 149 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 149 56.288 T 13-10-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 THITH_14510 304b64bd72308623cbe5fcafa14625cd 149 SUPERFAMILY SSF89447 1 131 9.94E-48 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily THITH_14510 304b64bd72308623cbe5fcafa14625cd 149 Gene3D G3DSA:2.40.330.20 1 140 2.7E-46 T 13-10-2018 IPR038619 MraZ superfamily THITH_02825 8e2c200b190d973c459a9afdf0961a16 113 Pfam PF01187 Macrophage migration inhibitory factor (MIF) 2 113 4.7E-25 T 13-10-2018 IPR001398 Macrophage migration inhibitory factor THITH_02825 8e2c200b190d973c459a9afdf0961a16 113 ProDom PD004816 MACROPHAGE MIGRATION INHIBITORY FACTOR TAUTOMERASE MIF PHENYLPYRUVATE CYTOKINE RESPONSE INFLAMMATORY 27 113 1.0E-25 T 13-10-2018 IPR001398 Macrophage migration inhibitory factor THITH_02825 8e2c200b190d973c459a9afdf0961a16 113 Gene3D G3DSA:3.30.429.10 1 113 1.3E-39 T 13-10-2018 IPR014347 Tautomerase/MIF superfamily THITH_02825 8e2c200b190d973c459a9afdf0961a16 113 SUPERFAMILY SSF55331 1 113 1.22E-34 T 13-10-2018 IPR014347 Tautomerase/MIF superfamily THITH_06960 5068402d3eb0f170e6c1d9afcf4181ed 189 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 10 172 2.7E-32 T 13-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 THITH_06960 5068402d3eb0f170e6c1d9afcf4181ed 189 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 1 175 6.7E-53 T 13-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 THITH_06960 5068402d3eb0f170e6c1d9afcf4181ed 189 SUPERFAMILY SSF53323 1 176 2.09E-41 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 THITH_06960 5068402d3eb0f170e6c1d9afcf4181ed 189 Gene3D G3DSA:3.40.920.10 1 177 2.4E-52 T 13-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 THITH_04655 78e831b0eb129501edd43142ae86c3d9 78 Gene3D G3DSA:3.40.1620.10 2 38 6.4E-6 T 13-10-2018 THITH_04655 78e831b0eb129501edd43142ae86c3d9 78 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 6 41 2.0E-8 T 13-10-2018 THITH_04655 78e831b0eb129501edd43142ae86c3d9 78 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 3 40 1.2E-9 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THITH_04655 78e831b0eb129501edd43142ae86c3d9 78 SUPERFAMILY SSF143120 2 41 2.35E-8 T 13-10-2018 IPR036165 YefM-like superfamily THITH_17355 2081e8b1661470d4ef312e22739ab0c2 815 SUPERFAMILY SSF51735 45 336 3.1E-41 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_17355 2081e8b1661470d4ef312e22739ab0c2 815 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 48 409 2.7E-76 T 13-10-2018 IPR010080 Thioester reductase-like domain THITH_17355 2081e8b1661470d4ef312e22739ab0c2 815 Gene3D G3DSA:3.40.50.720 23 416 7.7E-88 T 13-10-2018 THITH_17355 2081e8b1661470d4ef312e22739ab0c2 815 SUPERFAMILY SSF56112 532 781 6.23E-19 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily THITH_17355 2081e8b1661470d4ef312e22739ab0c2 815 Pfam PF07993 Male sterility protein 49 284 9.4E-56 T 13-10-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 THITH_17355 2081e8b1661470d4ef312e22739ab0c2 815 Gene3D G3DSA:3.90.1200.10 585 796 2.6E-12 T 13-10-2018 THITH_15465 ccf3918ccd642fabde6e7caf24958fb0 306 Gene3D G3DSA:2.60.120.10 36 287 2.5E-65 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_15465 ccf3918ccd642fabde6e7caf24958fb0 306 Gene3D G3DSA:2.60.120.10 164 262 2.5E-65 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_15465 ccf3918ccd642fabde6e7caf24958fb0 306 Pfam PF05726 Pirin C-terminal cupin domain 195 291 2.6E-21 T 13-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 THITH_15465 ccf3918ccd642fabde6e7caf24958fb0 306 SUPERFAMILY SSF51182 26 304 3.5E-75 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily THITH_15465 ccf3918ccd642fabde6e7caf24958fb0 306 Pfam PF02678 Pirin 37 142 1.4E-29 T 13-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 THITH_15465 ccf3918ccd642fabde6e7caf24958fb0 306 PIRSF PIRSF006232 20 300 1.2E-81 T 13-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 THITH_02250 00f886752b1c0e7afd66b11f01cd91af 140 Gene3D G3DSA:3.40.50.1010 1 128 1.3E-18 T 13-10-2018 THITH_02250 00f886752b1c0e7afd66b11f01cd91af 140 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 2 137 10.296 T 13-10-2018 IPR022907 VapC family GO:0004540 THITH_02250 00f886752b1c0e7afd66b11f01cd91af 140 Pfam PF01850 PIN domain 3 130 2.9E-14 T 13-10-2018 IPR002716 PIN domain THITH_02250 00f886752b1c0e7afd66b11f01cd91af 140 SUPERFAMILY SSF88723 1 131 8.97E-18 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_05510 a7f715954c5d8e2c15f8b20880cdb59d 183 Pfam PF09831 Uncharacterized protein conserved in bacteria (DUF2058) 4 183 1.1E-55 T 13-10-2018 IPR018636 Protein of unknown function DUF2058 THITH_02035 500c4ef66a30473d613709fa9683294b 346 Gene3D G3DSA:3.90.550.10 3 241 1.4E-46 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_02035 500c4ef66a30473d613709fa9683294b 346 Pfam PF00535 Glycosyl transferase family 2 13 175 3.4E-28 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THITH_02035 500c4ef66a30473d613709fa9683294b 346 SUPERFAMILY SSF53448 6 270 1.94E-49 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_00105 a26584d8a5c4209ef6a65cd361dafb90 267 SUPERFAMILY SSF158544 99 201 6.02E-18 T 13-10-2018 IPR038072 GspK, central domain superfamily THITH_00105 a26584d8a5c4209ef6a65cd361dafb90 267 Gene3D G3DSA:1.10.40.60 98 203 3.1E-18 T 13-10-2018 IPR038072 GspK, central domain superfamily THITH_00105 a26584d8a5c4209ef6a65cd361dafb90 267 PIRSF PIRSF002786 1 233 1.2E-32 T 13-10-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 THITH_00105 a26584d8a5c4209ef6a65cd361dafb90 267 Pfam PF03934 Type II secretion system (T2SS), protein K 32 219 3.9E-29 T 13-10-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 THITH_17185 f7a109ed86c118c7e69120d2c26ede4c 266 SUPERFAMILY SSF52833 63 240 1.07E-35 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_17185 f7a109ed86c118c7e69120d2c26ede4c 266 Pfam PF13462 Thioredoxin 66 210 8.4E-25 T 13-10-2018 IPR012336 Thioredoxin-like fold THITH_17185 f7a109ed86c118c7e69120d2c26ede4c 266 Gene3D G3DSA:3.40.30.10 42 246 4.4E-37 T 13-10-2018 THITH_14780 bc999e9fae473293814f1015295fa61e 318 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 7 316 1.1E-119 T 13-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 THITH_14780 bc999e9fae473293814f1015295fa61e 318 SUPERFAMILY SSF53271 72 308 1.63E-63 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like THITH_14780 bc999e9fae473293814f1015295fa61e 318 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 7 317 48.443 T 13-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 THITH_14780 bc999e9fae473293814f1015295fa61e 318 SMART SM01400 7 124 1.4E-78 T 13-10-2018 THITH_14780 bc999e9fae473293814f1015295fa61e 318 Gene3D G3DSA:3.40.50.2020 151 293 7.3E-127 T 13-10-2018 THITH_14780 bc999e9fae473293814f1015295fa61e 318 Gene3D G3DSA:3.40.50.2020 10 305 7.3E-127 T 13-10-2018 THITH_14780 bc999e9fae473293814f1015295fa61e 318 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 7 124 1.2E-48 T 13-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 THITH_14780 bc999e9fae473293814f1015295fa61e 318 Pfam PF14572 Phosphoribosyl synthetase-associated domain 205 316 9.6E-30 T 13-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 THITH_10255 377764c48e22d3cdb487dce7f8d89939 494 Pfam PF01476 LysM domain 445 487 1.1E-8 T 13-10-2018 IPR018392 LysM domain THITH_10255 377764c48e22d3cdb487dce7f8d89939 494 SUPERFAMILY SSF54106 443 489 1.09E-5 T 13-10-2018 THITH_10255 377764c48e22d3cdb487dce7f8d89939 494 Pfam PF01464 Transglycosylase SLT domain 205 305 3.9E-18 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 THITH_10255 377764c48e22d3cdb487dce7f8d89939 494 SMART SM00257 444 490 8.6E-5 T 13-10-2018 IPR018392 LysM domain THITH_10255 377764c48e22d3cdb487dce7f8d89939 494 SUPERFAMILY SSF53955 197 343 1.55E-30 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily THITH_10255 377764c48e22d3cdb487dce7f8d89939 494 Gene3D G3DSA:3.10.350.10 444 488 1.3E-9 T 13-10-2018 IPR036779 LysM domain superfamily THITH_10255 377764c48e22d3cdb487dce7f8d89939 494 Gene3D G3DSA:1.10.530.10 196 342 1.1E-28 T 13-10-2018 THITH_02800 bb5086e7ec50428f9fe65e335e8cee19 125 Pfam PF09842 Predicted membrane protein (DUF2069) 8 108 2.4E-28 T 13-10-2018 IPR018643 Protein of unknown function DUF2069, membrane THITH_14795 535d72b7da97f2cc8b49196ce228bf55 199 TIGRFAM TIGR00548 lolB: outer membrane lipoprotein LolB 2 192 2.4E-25 T 13-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 THITH_14795 535d72b7da97f2cc8b49196ce228bf55 199 Pfam PF03550 Outer membrane lipoprotein LolB 41 191 5.7E-36 T 13-10-2018 IPR004565 Outer membrane lipoprotein LolB GO:0009279|GO:0015031 THITH_14795 535d72b7da97f2cc8b49196ce228bf55 199 SUPERFAMILY SSF89392 11 193 4.71E-33 T 13-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX THITH_14795 535d72b7da97f2cc8b49196ce228bf55 199 Gene3D G3DSA:2.50.20.10 21 193 1.0E-37 T 13-10-2018 THITH_00645 83dbcfa746881a4abad2549937602651 718 Gene3D G3DSA:1.20.1560.10 154 466 2.9E-53 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THITH_00645 83dbcfa746881a4abad2549937602651 718 Pfam PF00005 ABC transporter 499 648 7.1E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_00645 83dbcfa746881a4abad2549937602651 718 Gene3D G3DSA:3.90.70.10 12 139 1.2E-31 T 13-10-2018 THITH_00645 83dbcfa746881a4abad2549937602651 718 Pfam PF00664 ABC transporter transmembrane region 171 427 1.7E-24 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 THITH_00645 83dbcfa746881a4abad2549937602651 718 Gene3D G3DSA:3.40.50.300 473 717 1.4E-81 T 13-10-2018 THITH_00645 83dbcfa746881a4abad2549937602651 718 SMART SM00382 508 694 1.3E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_00645 83dbcfa746881a4abad2549937602651 718 TIGRFAM TIGR03375 type_I_sec_LssB: type I secretion system ATPase 16 711 9.2E-280 T 13-10-2018 IPR017750 ATPase, type I secretion system THITH_00645 83dbcfa746881a4abad2549937602651 718 SUPERFAMILY SSF52540 474 706 2.09E-76 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00645 83dbcfa746881a4abad2549937602651 718 SUPERFAMILY SSF90123 155 467 1.44E-51 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THITH_17115 242a6f9605e81e2a1d373feae3e6d77b 360 Pfam PF00512 His Kinase A (phospho-acceptor) domain 143 196 7.1E-13 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_17115 242a6f9605e81e2a1d373feae3e6d77b 360 SMART SM00387 243 358 1.0E-26 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_17115 242a6f9605e81e2a1d373feae3e6d77b 360 SMART SM00388 139 204 2.3E-11 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_17115 242a6f9605e81e2a1d373feae3e6d77b 360 SMART SM00091 12 78 0.0096 T 13-10-2018 IPR000014 PAS domain THITH_17115 242a6f9605e81e2a1d373feae3e6d77b 360 SUPERFAMILY SSF47384 130 196 1.57E-12 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_17115 242a6f9605e81e2a1d373feae3e6d77b 360 SUPERFAMILY SSF55874 205 356 5.37E-36 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_17115 242a6f9605e81e2a1d373feae3e6d77b 360 Gene3D G3DSA:3.30.565.10 202 357 5.7E-38 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_17115 242a6f9605e81e2a1d373feae3e6d77b 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 319 337 7.0E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_17115 242a6f9605e81e2a1d373feae3e6d77b 360 PRINTS PR00344 Bacterial sensor protein C-terminal signature 290 304 7.0E-9 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_17115 242a6f9605e81e2a1d373feae3e6d77b 360 Gene3D G3DSA:3.30.450.20 16 122 1.6E-12 T 13-10-2018 THITH_17115 242a6f9605e81e2a1d373feae3e6d77b 360 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 244 357 2.8E-16 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_17115 242a6f9605e81e2a1d373feae3e6d77b 360 SUPERFAMILY SSF55785 19 109 4.0E-7 T 13-10-2018 IPR035965 PAS domain superfamily THITH_17115 242a6f9605e81e2a1d373feae3e6d77b 360 Gene3D G3DSA:1.10.287.130 123 198 2.4E-12 T 13-10-2018 THITH_00725 31820f5989f2e3f8bcd7a8cc2cbf3cd7 865 Gene3D G3DSA:2.60.120.380 82 175 4.8E-10 T 13-10-2018 THITH_00725 31820f5989f2e3f8bcd7a8cc2cbf3cd7 865 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 329 340 - T 13-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site THITH_00725 31820f5989f2e3f8bcd7a8cc2cbf3cd7 865 PRINTS PR00723 Subtilisin serine protease family (S8) signature 564 580 4.5E-12 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related THITH_00725 31820f5989f2e3f8bcd7a8cc2cbf3cd7 865 PRINTS PR00723 Subtilisin serine protease family (S8) signature 381 394 4.5E-12 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related THITH_00725 31820f5989f2e3f8bcd7a8cc2cbf3cd7 865 PRINTS PR00723 Subtilisin serine protease family (S8) signature 324 343 4.5E-12 T 13-10-2018 IPR015500 Peptidase S8, subtilisin-related THITH_00725 31820f5989f2e3f8bcd7a8cc2cbf3cd7 865 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 385 395 - T 13-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site THITH_00725 31820f5989f2e3f8bcd7a8cc2cbf3cd7 865 Gene3D G3DSA:3.40.50.200 293 632 9.5E-83 T 13-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 THITH_00725 31820f5989f2e3f8bcd7a8cc2cbf3cd7 865 SUPERFAMILY SSF52743 302 631 8.77E-69 T 13-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 THITH_00725 31820f5989f2e3f8bcd7a8cc2cbf3cd7 865 Pfam PF00082 Subtilase family 326 600 1.3E-36 T 13-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 THITH_00725 31820f5989f2e3f8bcd7a8cc2cbf3cd7 865 PIRSF PIRSF037893 4 859 7.2E-208 T 13-10-2018 IPR017309 Peptidase S8A, subtilisin-related, proteobacteria THITH_12005 c1841f001f02131b0508ff3cee7c15bd 110 Gene3D G3DSA:1.10.10.370 40 110 5.5E-36 T 13-10-2018 THITH_12005 c1841f001f02131b0508ff3cee7c15bd 110 SUPERFAMILY SSF69721 2 110 4.58E-43 T 13-10-2018 IPR025526 DsrC-like domain superfamily THITH_12005 c1841f001f02131b0508ff3cee7c15bd 110 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 4 110 4.4E-50 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_12005 c1841f001f02131b0508ff3cee7c15bd 110 Gene3D G3DSA:3.30.1420.10 1 38 1.3E-16 T 13-10-2018 THITH_12005 c1841f001f02131b0508ff3cee7c15bd 110 Pfam PF04358 DsrC like protein 5 110 3.7E-47 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_12005 c1841f001f02131b0508ff3cee7c15bd 110 PIRSF PIRSF006223 3 110 6.5E-45 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_04415 b0f7de0d2ceb7edac799bec3979b72cb 170 TIGRFAM TIGR01749 fabA: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA 2 170 1.1E-90 T 13-10-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THITH_04415 b0f7de0d2ceb7edac799bec3979b72cb 170 Pfam PF07977 FabA-like domain 27 156 2.1E-51 T 13-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THITH_04415 b0f7de0d2ceb7edac799bec3979b72cb 170 Hamap MF_00405 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase [fabA]. 1 170 49.751 T 13-10-2018 IPR010083 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA GO:0005737|GO:0006633|GO:0008693 KEGG: 00061+4.2.1.59+5.3.3.14|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THITH_04415 b0f7de0d2ceb7edac799bec3979b72cb 170 SUPERFAMILY SSF54637 3 168 1.57E-58 T 13-10-2018 IPR029069 HotDog domain superfamily THITH_04415 b0f7de0d2ceb7edac799bec3979b72cb 170 Gene3D G3DSA:3.10.129.10 1 170 1.1E-66 T 13-10-2018 THITH_10845 9f58f9e6a972d38503eeb3fe1f0e9184 246 SUPERFAMILY SSF46689 8 84 2.0E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_10845 9f58f9e6a972d38503eeb3fe1f0e9184 246 Gene3D G3DSA:1.10.357.10 62 178 2.5E-7 T 13-10-2018 THITH_10845 9f58f9e6a972d38503eeb3fe1f0e9184 246 Gene3D G3DSA:1.10.10.60 13 61 8.3E-15 T 13-10-2018 THITH_10845 9f58f9e6a972d38503eeb3fe1f0e9184 246 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 1.6E-5 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THITH_10845 9f58f9e6a972d38503eeb3fe1f0e9184 246 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 1.6E-5 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THITH_10845 9f58f9e6a972d38503eeb3fe1f0e9184 246 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 9.1E-11 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THITH_16005 2f4ebee2d6688a5a131c8f29c4450f29 192 SUPERFAMILY SSF143456 13 192 1.57E-64 T 13-10-2018 THITH_16005 2f4ebee2d6688a5a131c8f29c4450f29 192 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 11 192 37.041 T 13-10-2018 IPR003774 Protein of unknown function UPF0301 THITH_16005 2f4ebee2d6688a5a131c8f29c4450f29 192 Gene3D G3DSA:3.40.1740.10 9 192 8.5E-69 T 13-10-2018 THITH_16005 2f4ebee2d6688a5a131c8f29c4450f29 192 Pfam PF02622 Uncharacterized ACR, COG1678 22 179 9.9E-49 T 13-10-2018 IPR003774 Protein of unknown function UPF0301 THITH_07915 c33637f90189b2196ea65e41808ed759 206 Pfam PF09835 Uncharacterized protein conserved in bacteria (DUF2062) 25 162 2.4E-45 T 13-10-2018 IPR018639 Domain of unknown function DUF2062 THITH_09170 a1cac1bd0b2061cc60cd1a31cb7f8c21 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 27 54 6.0E-72 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_09170 a1cac1bd0b2061cc60cd1a31cb7f8c21 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 179 202 6.0E-72 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_09170 a1cac1bd0b2061cc60cd1a31cb7f8c21 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 64 90 6.0E-72 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_09170 a1cac1bd0b2061cc60cd1a31cb7f8c21 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 148 171 6.0E-72 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_09170 a1cac1bd0b2061cc60cd1a31cb7f8c21 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 304 329 6.0E-72 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_09170 a1cac1bd0b2061cc60cd1a31cb7f8c21 332 PRINTS PR00115 Fructose-1,6-bisphosphatase signature 205 232 6.0E-72 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_09170 a1cac1bd0b2061cc60cd1a31cb7f8c21 332 Gene3D G3DSA:3.30.540.10 1 194 8.8E-75 T 13-10-2018 THITH_09170 a1cac1bd0b2061cc60cd1a31cb7f8c21 332 Gene3D G3DSA:3.40.190.80 197 332 7.6E-54 T 13-10-2018 THITH_09170 a1cac1bd0b2061cc60cd1a31cb7f8c21 332 SUPERFAMILY SSF56655 2 327 8.32E-109 T 13-10-2018 THITH_09170 a1cac1bd0b2061cc60cd1a31cb7f8c21 332 Hamap MF_01855 Fructose-1,6-bisphosphatase class 1 [fbp]. 2 330 41.023 T 13-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_09170 a1cac1bd0b2061cc60cd1a31cb7f8c21 332 PIRSF PIRSF500210 1 332 1.1E-120 T 13-10-2018 IPR028343 Fructose-1,6-bisphosphatase GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_09170 a1cac1bd0b2061cc60cd1a31cb7f8c21 332 Pfam PF00316 Fructose-1-6-bisphosphatase, N-terminal domain 3 193 2.1E-73 T 13-10-2018 IPR033391 Fructose-1-6-bisphosphatase class I, N-terminal KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_09170 a1cac1bd0b2061cc60cd1a31cb7f8c21 332 ProSitePatterns PS00124 Fructose-1-6-bisphosphatase active site. 270 282 - T 13-10-2018 IPR020548 Fructose-1,6-bisphosphatase, active site GO:0005975|GO:0042578 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_09170 a1cac1bd0b2061cc60cd1a31cb7f8c21 332 PIRSF PIRSF000904 1 332 7.8E-118 T 13-10-2018 IPR000146 Fructose-1,6-bisphosphatase class 1 GO:0005975|GO:0016791 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484|Reactome: R-HSA-70263 THITH_04465 6bc48173cc366a5290cd0f19faaf2b55 149 SUPERFAMILY SSF54909 13 125 8.5E-6 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel THITH_12625 ed0b30f4d8240266b84a3ec1808a2e08 106 Pfam PF08755 Hemimethylated DNA-binding protein YccV like 6 94 5.9E-26 T 13-10-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 THITH_12625 ed0b30f4d8240266b84a3ec1808a2e08 106 SMART SM00992 4 100 4.4E-39 T 13-10-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 THITH_12625 ed0b30f4d8240266b84a3ec1808a2e08 106 TIGRFAM TIGR02097 yccV: hemimethylated DNA binding domain 5 97 1.2E-29 T 13-10-2018 IPR011722 Hemimethylated DNA-binding domain GO:0003677 THITH_12625 ed0b30f4d8240266b84a3ec1808a2e08 106 SUPERFAMILY SSF141255 5 93 2.48E-32 T 13-10-2018 IPR036623 Hemimethylated DNA-binding domain superfamily GO:0003677 THITH_12625 ed0b30f4d8240266b84a3ec1808a2e08 106 Gene3D G3DSA:2.30.30.390 2 99 6.0E-34 T 13-10-2018 IPR036623 Hemimethylated DNA-binding domain superfamily GO:0003677 THITH_06780 5912263c00cdcb66e4c0a1fe37b28b0f 95 Gene3D G3DSA:2.40.50.970 1 74 9.2E-13 T 13-10-2018 IPR037254 HupF/HypC superfamily THITH_06780 5912263c00cdcb66e4c0a1fe37b28b0f 95 SUPERFAMILY SSF159127 1 75 3.14E-18 T 13-10-2018 IPR037254 HupF/HypC superfamily THITH_06780 5912263c00cdcb66e4c0a1fe37b28b0f 95 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 73 3.3E-19 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THITH_06780 5912263c00cdcb66e4c0a1fe37b28b0f 95 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 13-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site THITH_06780 5912263c00cdcb66e4c0a1fe37b28b0f 95 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 38 54 4.9E-11 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THITH_06780 5912263c00cdcb66e4c0a1fe37b28b0f 95 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 4.9E-11 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THITH_06780 5912263c00cdcb66e4c0a1fe37b28b0f 95 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 4.9E-11 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THITH_06780 5912263c00cdcb66e4c0a1fe37b28b0f 95 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 59 71 4.9E-11 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THITH_06780 5912263c00cdcb66e4c0a1fe37b28b0f 95 Pfam PF01455 HupF/HypC family 1 63 5.7E-18 T 13-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC THITH_16665 3d61c139653593b65aa6201a08236e8d 198 SUPERFAMILY SSF53597 1 195 2.88E-21 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 THITH_16665 3d61c139653593b65aa6201a08236e8d 198 Pfam PF01872 RibD C-terminal domain 3 169 1.2E-10 T 13-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 THITH_16665 3d61c139653593b65aa6201a08236e8d 198 Gene3D G3DSA:3.40.430.10 1 194 9.5E-41 T 13-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 THITH_11470 78085dd529934655a6d828a8b5a390fb 1064 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 53 214 2.1E-12 T 13-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 THITH_11470 78085dd529934655a6d828a8b5a390fb 1064 SUPERFAMILY SSF52540 288 506 1.48E-20 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_11470 78085dd529934655a6d828a8b5a390fb 1064 Pfam PF04851 Type III restriction enzyme, res subunit 290 490 3.3E-12 T 13-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 THITH_11470 78085dd529934655a6d828a8b5a390fb 1064 Gene3D G3DSA:3.40.50.300 652 752 1.5E-20 T 13-10-2018 THITH_11470 78085dd529934655a6d828a8b5a390fb 1064 Gene3D G3DSA:3.90.1570.50 107 179 2.8E-5 T 13-10-2018 THITH_11470 78085dd529934655a6d828a8b5a390fb 1064 SMART SM00487 285 519 1.7E-9 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_11470 78085dd529934655a6d828a8b5a390fb 1064 Gene3D G3DSA:3.40.50.300 290 500 1.5E-21 T 13-10-2018 THITH_14985 c921b182cef83216e2eb61cb617ab992 311 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 307 91.808 T 13-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 THITH_14985 c921b182cef83216e2eb61cb617ab992 311 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 10 301 3.0E-53 T 13-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 THITH_14985 c921b182cef83216e2eb61cb617ab992 311 Pfam PF03186 CobD/Cbib protein 9 283 4.3E-82 T 13-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 THITH_10405 b017da3fdf451bcfa24bc15a9ceb2709 152 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 4 146 2.0E-55 T 13-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THITH_10405 b017da3fdf451bcfa24bc15a9ceb2709 152 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 4 149 33.753 T 13-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THITH_10405 b017da3fdf451bcfa24bc15a9ceb2709 152 Pfam PF07977 FabA-like domain 13 141 3.9E-37 T 13-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THITH_10405 b017da3fdf451bcfa24bc15a9ceb2709 152 Gene3D G3DSA:3.10.129.10 3 150 1.0E-55 T 13-10-2018 THITH_10405 b017da3fdf451bcfa24bc15a9ceb2709 152 SUPERFAMILY SSF54637 8 147 2.38E-45 T 13-10-2018 IPR029069 HotDog domain superfamily THITH_07480 039d4ee68491717dd552afd35332f42e 97 PIRSF PIRSF006223 2 97 1.3E-16 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_07480 039d4ee68491717dd552afd35332f42e 97 Gene3D G3DSA:1.10.10.370 34 97 1.5E-15 T 13-10-2018 THITH_07480 039d4ee68491717dd552afd35332f42e 97 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 5 97 1.9E-18 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_07480 039d4ee68491717dd552afd35332f42e 97 Gene3D G3DSA:3.30.1420.10 5 33 1.8E-6 T 13-10-2018 THITH_07480 039d4ee68491717dd552afd35332f42e 97 Pfam PF04358 DsrC like protein 5 97 3.3E-21 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_07480 039d4ee68491717dd552afd35332f42e 97 SUPERFAMILY SSF69721 5 97 6.41E-28 T 13-10-2018 IPR025526 DsrC-like domain superfamily THITH_12660 7f41dab7550333de1b736bcb731183ce 561 Pfam PF10081 Alpha/beta-hydrolase family 254 542 2.3E-118 T 13-10-2018 IPR027787 Alpha/beta-hydrolase, catalytic domain THITH_12660 7f41dab7550333de1b736bcb731183ce 561 PIRSF PIRSF007542 1 556 7.4E-229 T 13-10-2018 IPR012037 Alpha/beta-hydrolase family THITH_12660 7f41dab7550333de1b736bcb731183ce 561 Pfam PF15420 Alpha/beta-hydrolase family N-terminus 30 237 8.8E-65 T 13-10-2018 IPR027788 Alpha/beta-hydrolase, N-terminal domain THITH_01140 1cd52ee8479e04503daff140f365edbd 134 SUPERFAMILY SSF88723 1 125 7.2E-19 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_01140 1cd52ee8479e04503daff140f365edbd 134 Gene3D G3DSA:3.40.50.1010 1 128 2.0E-46 T 13-10-2018 THITH_01140 1cd52ee8479e04503daff140f365edbd 134 Pfam PF01850 PIN domain 1 124 1.4E-18 T 13-10-2018 IPR002716 PIN domain THITH_01140 1cd52ee8479e04503daff140f365edbd 134 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 1 130 12.214 T 13-10-2018 IPR022907 VapC family GO:0004540 THITH_08880 e24d9aa7ff82448ccddcec4573c4bd26 158 SUPERFAMILY SSF56784 51 148 1.88E-20 T 13-10-2018 IPR036412 HAD-like superfamily THITH_08880 e24d9aa7ff82448ccddcec4573c4bd26 158 Gene3D G3DSA:3.40.50.1000 8 114 3.4E-15 T 13-10-2018 IPR023214 HAD superfamily THITH_12755 f44e501f0c4a49f63a66862b3373d856 54 PIRSF PIRSF036466 1 53 1.0E-20 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 THITH_12755 f44e501f0c4a49f63a66862b3373d856 54 Pfam PF07043 Protein of unknown function (DUF1328) 6 44 3.9E-15 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 THITH_12755 f44e501f0c4a49f63a66862b3373d856 54 Hamap MF_01361 UPF0391 membrane protein YtjA [ytjA]. 1 52 19.474 T 13-10-2018 IPR009760 Protein of unknown function DUF1328 GO:0005886 THITH_13500 152e9a7e50d5b3aff528a125fb7057b0 235 SUPERFAMILY SSF54423 31 82 4.45E-12 T 13-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 THITH_13500 152e9a7e50d5b3aff528a125fb7057b0 235 Pfam PF13098 Thioredoxin-like domain 112 230 9.4E-26 T 13-10-2018 IPR012336 Thioredoxin-like fold THITH_13500 152e9a7e50d5b3aff528a125fb7057b0 235 SUPERFAMILY SSF52833 94 233 6.06E-31 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_13500 152e9a7e50d5b3aff528a125fb7057b0 235 Gene3D G3DSA:3.40.30.10 80 234 7.8E-40 T 13-10-2018 THITH_13500 152e9a7e50d5b3aff528a125fb7057b0 235 Gene3D G3DSA:3.10.450.70 20 79 3.5E-15 T 13-10-2018 IPR009094 Disulphide bond isomerase DsbC/G, N-terminal domain superfamily GO:0042597 THITH_13500 152e9a7e50d5b3aff528a125fb7057b0 235 Pfam PF10411 Disulfide bond isomerase protein N-terminus 28 80 1.1E-18 T 13-10-2018 IPR018950 Disulphide bond isomerase, DsbC/G, N-terminal THITH_00810 e5828fd12c693e42bf9609ad236946ed 208 Gene3D G3DSA:1.20.1290.10 1 99 2.7E-12 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 THITH_00810 e5828fd12c693e42bf9609ad236946ed 208 Pfam PF02627 Carboxymuconolactone decarboxylase family 26 91 1.4E-5 T 13-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 THITH_00810 e5828fd12c693e42bf9609ad236946ed 208 Pfam PF00355 Rieske [2Fe-2S] domain 110 187 2.0E-13 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THITH_00810 e5828fd12c693e42bf9609ad236946ed 208 SUPERFAMILY SSF50022 110 207 5.24E-21 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THITH_00810 e5828fd12c693e42bf9609ad236946ed 208 Gene3D G3DSA:2.102.10.10 109 206 3.7E-21 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THITH_00810 e5828fd12c693e42bf9609ad236946ed 208 SUPERFAMILY SSF69118 8 95 6.91E-12 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 THITH_08705 8ac730c750f7adba70739be2285500ae 115 SUPERFAMILY SSF141371 30 104 4.12E-5 T 13-10-2018 THITH_08705 8ac730c750f7adba70739be2285500ae 115 Pfam PF07238 PilZ domain 14 98 5.3E-10 T 13-10-2018 IPR009875 PilZ domain GO:0035438 THITH_08705 8ac730c750f7adba70739be2285500ae 115 Gene3D G3DSA:2.40.10.220 2 115 9.1E-40 T 13-10-2018 THITH_15530 3244df28331a62d7a8eed45aff2eb67d 287 Pfam PF07722 Peptidase C26 122 252 4.0E-37 T 13-10-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 THITH_15530 3244df28331a62d7a8eed45aff2eb67d 287 SUPERFAMILY SSF52317 21 271 4.9E-35 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_11560 a6cdbc76a3fb794cbc86f80dc6adb5b9 266 SUPERFAMILY SSF55781 99 263 4.58E-16 T 13-10-2018 THITH_11560 a6cdbc76a3fb794cbc86f80dc6adb5b9 266 Gene3D G3DSA:3.30.450.40 117 261 1.8E-13 T 13-10-2018 IPR029016 GAF-like domain superfamily THITH_11560 a6cdbc76a3fb794cbc86f80dc6adb5b9 266 Pfam PF01590 GAF domain 119 257 3.8E-7 T 13-10-2018 IPR003018 GAF domain GO:0005515 THITH_11560 a6cdbc76a3fb794cbc86f80dc6adb5b9 266 SUPERFAMILY SSF158472 54 103 5.62E-9 T 13-10-2018 THITH_11560 a6cdbc76a3fb794cbc86f80dc6adb5b9 266 Gene3D G3DSA:1.20.1480.50 26 111 5.9E-8 T 13-10-2018 THITH_11560 a6cdbc76a3fb794cbc86f80dc6adb5b9 266 SMART SM00304 53 105 3.2E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_11560 a6cdbc76a3fb794cbc86f80dc6adb5b9 266 Pfam PF00672 HAMP domain 54 97 1.8E-7 T 13-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 THITH_14945 26b49c04f6a59ab46c89579cc51fd210 321 Gene3D G3DSA:1.10.3470.10 2 320 6.9E-84 T 13-10-2018 IPR037294 ABC transporter, BtuC-like THITH_14945 26b49c04f6a59ab46c89579cc51fd210 321 SUPERFAMILY SSF81345 8 317 8.76E-70 T 13-10-2018 IPR037294 ABC transporter, BtuC-like THITH_14945 26b49c04f6a59ab46c89579cc51fd210 321 Pfam PF01032 FecCD transport family 22 317 8.1E-78 T 13-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 THITH_09765 7f7a14bfbddcfb4d536290f288693af7 734 Gene3D G3DSA:3.40.390.10 188 393 3.8E-19 T 13-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 THITH_09765 7f7a14bfbddcfb4d536290f288693af7 734 Pfam PF13688 Metallo-peptidase family M12 193 375 2.8E-17 T 13-10-2018 THITH_09765 7f7a14bfbddcfb4d536290f288693af7 734 SUPERFAMILY SSF55486 194 362 3.91E-19 T 13-10-2018 THITH_09765 7f7a14bfbddcfb4d536290f288693af7 734 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 576 642 3.6E-11 T 13-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial THITH_09765 7f7a14bfbddcfb4d536290f288693af7 734 Gene3D G3DSA:2.60.120.380 557 657 3.5E-35 T 13-10-2018 THITH_17130 ba191517092e79c872794ca9e5a24259 227 SUPERFAMILY SSF102405 4 206 1.83E-60 T 13-10-2018 THITH_17130 ba191517092e79c872794ca9e5a24259 227 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 33 208 2.7E-42 T 13-10-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG THITH_17130 ba191517092e79c872794ca9e5a24259 227 Gene3D G3DSA:3.40.50.450 10 208 5.2E-67 T 13-10-2018 THITH_17130 ba191517092e79c872794ca9e5a24259 227 Pfam PF03641 Possible lysine decarboxylase 75 204 1.0E-32 T 13-10-2018 IPR031100 LOG family THITH_10360 42617d98e7c1a45c7c11476601c7fb28 437 Gene3D G3DSA:3.40.50.11540 52 230 5.6E-73 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10360 42617d98e7c1a45c7c11476601c7fb28 437 Gene3D G3DSA:3.10.20.600 231 333 1.4E-28 T 13-10-2018 THITH_10360 42617d98e7c1a45c7c11476601c7fb28 437 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 48 218 8.2E-42 T 13-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10360 42617d98e7c1a45c7c11476601c7fb28 437 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 350 361 - T 13-10-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10360 42617d98e7c1a45c7c11476601c7fb28 437 Gene3D G3DSA:1.20.1440.230 335 432 7.6E-32 T 13-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10360 42617d98e7c1a45c7c11476601c7fb28 437 SUPERFAMILY SSF142019 10 239 9.29E-78 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10360 42617d98e7c1a45c7c11476601c7fb28 437 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 342 420 4.5E-28 T 13-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10360 42617d98e7c1a45c7c11476601c7fb28 437 Pfam PF10531 SLBB domain 242 290 1.2E-7 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10360 42617d98e7c1a45c7c11476601c7fb28 437 SMART SM00928 337 382 5.2E-25 T 13-10-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10360 42617d98e7c1a45c7c11476601c7fb28 437 SUPERFAMILY SSF142984 240 331 1.57E-14 T 13-10-2018 THITH_10360 42617d98e7c1a45c7c11476601c7fb28 437 SUPERFAMILY SSF140490 334 429 3.66E-34 T 13-10-2018 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_07950 a36d8a9e52613eafc3da654f5cf1c24b 390 Gene3D G3DSA:3.90.1150.10 43 381 4.0E-115 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_07950 a36d8a9e52613eafc3da654f5cf1c24b 390 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 29 385 1.3E-106 T 13-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 THITH_07950 a36d8a9e52613eafc3da654f5cf1c24b 390 Pfam PF00155 Aminotransferase class I and II 52 383 2.1E-49 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THITH_07950 a36d8a9e52613eafc3da654f5cf1c24b 390 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 24 387 60.668 T 13-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 THITH_07950 a36d8a9e52613eafc3da654f5cf1c24b 390 Gene3D G3DSA:3.40.640.10 65 295 4.0E-115 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_07950 a36d8a9e52613eafc3da654f5cf1c24b 390 SUPERFAMILY SSF53383 35 387 5.7E-80 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_00580 f3c5d07048f92f16483bbcb0860908dd 193 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 57 166 2.2E-14 T 13-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein THITH_08505 c89d9412985c715d42224d0d7b8bdfd9 230 Pfam PF00005 ABC transporter 24 173 2.4E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_08505 c89d9412985c715d42224d0d7b8bdfd9 230 Gene3D G3DSA:3.40.50.300 1 228 3.2E-70 T 13-10-2018 THITH_08505 c89d9412985c715d42224d0d7b8bdfd9 230 SMART SM00382 32 228 3.4E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_08505 c89d9412985c715d42224d0d7b8bdfd9 230 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_08505 c89d9412985c715d42224d0d7b8bdfd9 230 SUPERFAMILY SSF52540 3 224 5.6E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_09440 97f4327cf24503c33d74289e3a6cc21f 112 Gene3D G3DSA:1.20.1300.10 4 108 8.2E-23 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_09440 97f4327cf24503c33d74289e3a6cc21f 112 TIGRFAM TIGR02968 succ_dehyd_anc: succinate dehydrogenase, hydrophobic membrane anchor protein 6 106 3.6E-25 T 13-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 THITH_09440 97f4327cf24503c33d74289e3a6cc21f 112 PIRSF PIRSF000169 3 109 7.8E-22 T 13-10-2018 IPR014312 Succinate dehydrogenase, hydrophobic membrane anchor GO:0000104|GO:0006099|GO:0016021|GO:0020037 THITH_09440 97f4327cf24503c33d74289e3a6cc21f 112 SUPERFAMILY SSF81343 6 106 1.37E-19 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_09440 97f4327cf24503c33d74289e3a6cc21f 112 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 9 89 9.3E-8 T 13-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_03600 58ae4ecce0fee1068876225398a6fe2c 702 Pfam PF07715 TonB-dependent Receptor Plug Domain 43 148 2.3E-25 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain THITH_03600 58ae4ecce0fee1068876225398a6fe2c 702 Pfam PF00593 TonB dependent receptor 276 697 3.5E-44 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel THITH_03600 58ae4ecce0fee1068876225398a6fe2c 702 SUPERFAMILY SSF56935 18 702 1.04E-113 T 13-10-2018 THITH_03600 58ae4ecce0fee1068876225398a6fe2c 702 Gene3D G3DSA:2.40.170.20 161 702 8.9E-78 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily THITH_03600 58ae4ecce0fee1068876225398a6fe2c 702 Gene3D G3DSA:2.170.130.10 28 153 2.3E-34 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily THITH_11980 44f5349d20803498d42d00b06a1b1986 421 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 161 378 3.1E-38 T 13-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THITH_11980 44f5349d20803498d42d00b06a1b1986 421 SUPERFAMILY SSF55124 6 160 1.09E-59 T 13-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THITH_11980 44f5349d20803498d42d00b06a1b1986 421 SUPERFAMILY SSF56014 162 402 2.29E-53 T 13-10-2018 THITH_11980 44f5349d20803498d42d00b06a1b1986 421 Gene3D G3DSA:3.30.70.2500 60 158 1.5E-39 T 13-10-2018 THITH_11980 44f5349d20803498d42d00b06a1b1986 421 SUPERFAMILY SSF54862 222 300 1.47E-15 T 13-10-2018 THITH_11980 44f5349d20803498d42d00b06a1b1986 421 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 90 153 3.7E-8 T 13-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 THITH_11980 44f5349d20803498d42d00b06a1b1986 421 Gene3D G3DSA:3.30.70.20 233 311 5.0E-111 T 13-10-2018 THITH_11980 44f5349d20803498d42d00b06a1b1986 421 Gene3D G3DSA:3.30.413.10 159 397 5.0E-111 T 13-10-2018 THITH_11980 44f5349d20803498d42d00b06a1b1986 421 TIGRFAM TIGR02064 dsrA: sulfite reductase, dissimilatory-type alpha subunit 11 412 1.1E-186 T 13-10-2018 IPR011806 Sulphite reductase, dissimilatory-type alpha subunit GO:0018551|GO:0020037|GO:0051539|GO:0055114 THITH_01535 ca40063dcf54916ff750943007d5c110 476 Gene3D G3DSA:3.40.50.300 21 217 2.4E-32 T 13-10-2018 THITH_01535 ca40063dcf54916ff750943007d5c110 476 Pfam PF13604 AAA domain 42 218 4.8E-26 T 13-10-2018 THITH_01535 ca40063dcf54916ff750943007d5c110 476 Gene3D G3DSA:3.40.50.300 240 460 2.6E-21 T 13-10-2018 THITH_01535 ca40063dcf54916ff750943007d5c110 476 Pfam PF13538 UvrD-like helicase C-terminal domain 413 462 7.2E-10 T 13-10-2018 IPR027785 UvrD-like helicase C-terminal domain THITH_01535 ca40063dcf54916ff750943007d5c110 476 SUPERFAMILY SSF52540 41 470 2.62E-33 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01535 ca40063dcf54916ff750943007d5c110 476 Gene3D G3DSA:2.30.30.780 289 412 2.6E-21 T 13-10-2018 THITH_08180 a4a4599257c88fb4126c1e1db1dffcb6 423 Gene3D G3DSA:1.20.1250.20 3 184 7.7E-44 T 13-10-2018 THITH_08180 a4a4599257c88fb4126c1e1db1dffcb6 423 Gene3D G3DSA:1.20.1250.20 193 412 3.0E-50 T 13-10-2018 THITH_08180 a4a4599257c88fb4126c1e1db1dffcb6 423 SUPERFAMILY SSF103473 4 405 2.49E-60 T 13-10-2018 IPR036259 MFS transporter superfamily THITH_08180 a4a4599257c88fb4126c1e1db1dffcb6 423 Pfam PF07690 Major Facilitator Superfamily 18 368 1.5E-40 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THITH_05405 dbf2134f35ac9515fe35532a19321a88 135 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 2 100 5.8E-26 T 13-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 THITH_05405 dbf2134f35ac9515fe35532a19321a88 135 Pfam PF13806 Rieske-like [2Fe-2S] domain 2 99 1.5E-13 T 13-10-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 THITH_05405 dbf2134f35ac9515fe35532a19321a88 135 Gene3D G3DSA:2.102.10.10 1 106 1.0E-25 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THITH_05405 dbf2134f35ac9515fe35532a19321a88 135 SUPERFAMILY SSF50022 1 104 1.2E-33 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THITH_17465 552fe438b8d74ae44694cac58a584e64 212 Pfam PF01991 ATP synthase (E/31 kDa) subunit 11 199 1.8E-18 T 13-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_17465 552fe438b8d74ae44694cac58a584e64 212 Gene3D G3DSA:3.30.2320.30 81 200 1.7E-21 T 13-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_17465 552fe438b8d74ae44694cac58a584e64 212 SUPERFAMILY SSF160527 83 199 1.57E-19 T 13-10-2018 THITH_07675 00c8944cee297931dad0cdf76f3583f0 65 Pfam PF01783 Ribosomal L32p protein family 2 56 9.8E-21 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_07675 00c8944cee297931dad0cdf76f3583f0 65 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 54 17.415 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_07675 00c8944cee297931dad0cdf76f3583f0 65 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 54 1.6E-19 T 13-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_07675 00c8944cee297931dad0cdf76f3583f0 65 SUPERFAMILY SSF57829 2 54 7.32E-18 T 13-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 THITH_05775 cf2d99b0b050249169c1b5eb6830c8e8 353 SUPERFAMILY SSF51905 1 266 5.61E-39 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_05775 cf2d99b0b050249169c1b5eb6830c8e8 353 Gene3D G3DSA:3.50.50.60 1 347 2.4E-88 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_05775 cf2d99b0b050249169c1b5eb6830c8e8 353 Gene3D G3DSA:3.30.9.10 77 309 2.4E-88 T 13-10-2018 THITH_05775 cf2d99b0b050249169c1b5eb6830c8e8 353 Pfam PF01266 FAD dependent oxidoreductase 1 346 9.3E-52 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THITH_03745 87cb2f01cc50b92af90ce74369c5fef1 291 Gene3D G3DSA:1.10.150.130 8 94 4.3E-13 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal THITH_03745 87cb2f01cc50b92af90ce74369c5fef1 291 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 11 89 1.9E-15 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THITH_03745 87cb2f01cc50b92af90ce74369c5fef1 291 Pfam PF00589 Phage integrase family 108 275 2.0E-40 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THITH_03745 87cb2f01cc50b92af90ce74369c5fef1 291 SUPERFAMILY SSF56349 12 280 1.77E-53 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THITH_03745 87cb2f01cc50b92af90ce74369c5fef1 291 Gene3D G3DSA:1.10.443.10 100 290 3.7E-51 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 THITH_15650 6bf9ac3d822c0bffed7aecff97339833 334 SMART SM00876 221 313 2.7E-44 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 THITH_15650 6bf9ac3d822c0bffed7aecff97339833 334 PIRSF PIRSF001619 1 317 7.1E-130 T 13-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 THITH_15650 6bf9ac3d822c0bffed7aecff97339833 334 SUPERFAMILY SSF102114 6 313 3.14E-95 T 13-10-2018 THITH_15650 6bf9ac3d822c0bffed7aecff97339833 334 TIGRFAM TIGR00433 bioB: biotin synthase 15 311 4.7E-121 T 13-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 THITH_15650 6bf9ac3d822c0bffed7aecff97339833 334 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 221 311 9.3E-19 T 13-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 THITH_15650 6bf9ac3d822c0bffed7aecff97339833 334 Gene3D G3DSA:3.20.20.70 5 315 7.4E-125 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_15650 6bf9ac3d822c0bffed7aecff97339833 334 SMART SM00729 44 250 3.8E-37 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THITH_15650 6bf9ac3d822c0bffed7aecff97339833 334 Hamap MF_01694 Biotin synthase [bioB]. 6 314 42.357 T 13-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 THITH_15650 6bf9ac3d822c0bffed7aecff97339833 334 Pfam PF04055 Radical SAM superfamily 51 208 7.0E-17 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THITH_12340 2f64bd2775628da7ddbb3a17c677f9c4 96 Pfam PF00936 BMC domain 9 85 6.6E-26 T 13-10-2018 IPR000249 Microcompartment protein, bacteria THITH_12340 2f64bd2775628da7ddbb3a17c677f9c4 96 ProSitePatterns PS01139 Bacterial microcompartiments proteins signature. 26 45 - T 13-10-2018 IPR020808 Bacterial microcompartments protein, conserved site THITH_12340 2f64bd2775628da7ddbb3a17c677f9c4 96 ProDom PD003442 UTILIZATION MICROCOMPARTMENTS PROPANEDIOL CONCENTRATING CARBON DIOXIDE MECHANISM CARBOXYSOME ETHANOLAMINE SHELL 9 70 2.0E-19 T 13-10-2018 THITH_12340 2f64bd2775628da7ddbb3a17c677f9c4 96 Gene3D G3DSA:3.30.70.1710 2 91 1.8E-36 T 13-10-2018 THITH_12340 2f64bd2775628da7ddbb3a17c677f9c4 96 SMART SM00877 8 85 8.5E-31 T 13-10-2018 IPR000249 Microcompartment protein, bacteria THITH_12340 2f64bd2775628da7ddbb3a17c677f9c4 96 SUPERFAMILY SSF143414 9 94 4.45E-28 T 13-10-2018 IPR037233 CcmK-like superfamily THITH_01155 a64bef96f258d4d3af76321185733c3e 2140 SMART SM00487 76 307 6.8E-16 T 13-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain THITH_01155 a64bef96f258d4d3af76321185733c3e 2140 SUPERFAMILY SSF52540 97 1107 3.43E-26 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01155 a64bef96f258d4d3af76321185733c3e 2140 Pfam PF00270 DEAD/DEAH box helicase 83 274 2.8E-16 T 13-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 THITH_01155 a64bef96f258d4d3af76321185733c3e 2140 Pfam PF09369 Domain of unknown function (DUF1998) 1558 1645 3.1E-11 T 13-10-2018 IPR018973 DEAD/DEAH-box helicase, putative THITH_01155 a64bef96f258d4d3af76321185733c3e 2140 Pfam PF00271 Helicase conserved C-terminal domain 998 1061 2.7E-7 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_01155 a64bef96f258d4d3af76321185733c3e 2140 SMART SM00490 980 1063 2.4E-11 T 13-10-2018 IPR001650 Helicase, C-terminal THITH_01155 a64bef96f258d4d3af76321185733c3e 2140 SUPERFAMILY SSF52540 79 276 8.06E-26 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01155 a64bef96f258d4d3af76321185733c3e 2140 Gene3D G3DSA:3.40.50.300 71 289 2.4E-34 T 13-10-2018 THITH_01155 a64bef96f258d4d3af76321185733c3e 2140 Gene3D G3DSA:3.40.50.300 972 1086 1.6E-15 T 13-10-2018 THITH_02685 1774651c2fa7b6d624db5fbe37bee88b 256 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 229 2.9E-86 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THITH_02685 1774651c2fa7b6d624db5fbe37bee88b 256 Gene3D G3DSA:1.10.1270.20 167 254 3.1E-29 T 13-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THITH_02685 1774651c2fa7b6d624db5fbe37bee88b 256 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 222 2.7E-58 T 13-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THITH_02685 1774651c2fa7b6d624db5fbe37bee88b 256 SUPERFAMILY SSF75217 1 242 5.69E-93 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases THITH_02685 1774651c2fa7b6d624db5fbe37bee88b 256 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 256 106.368 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THITH_02685 1774651c2fa7b6d624db5fbe37bee88b 256 PIRSF PIRSF000386 1 251 1.8E-90 T 13-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 THITH_02685 1774651c2fa7b6d624db5fbe37bee88b 256 Gene3D G3DSA:3.40.1280.10 1 166 9.8E-61 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THITH_09725 83e76863d4016472aefe61e2eb2253df 240 SUPERFAMILY SSF56281 17 217 7.99E-46 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_09725 83e76863d4016472aefe61e2eb2253df 240 SMART SM00849 21 187 1.8E-30 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_09725 83e76863d4016472aefe61e2eb2253df 240 Pfam PF00753 Metallo-beta-lactamase superfamily 21 173 2.2E-20 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_09725 83e76863d4016472aefe61e2eb2253df 240 Gene3D G3DSA:3.60.15.10 12 231 9.6E-57 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_00345 f620cb7db7cc4c6634cf1bc545bd2486 114 Gene3D G3DSA:2.30.30.110 15 112 2.0E-11 T 13-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THITH_00345 f620cb7db7cc4c6634cf1bc545bd2486 114 SUPERFAMILY SSF50118 2 111 2.18E-13 T 13-10-2018 THITH_00345 f620cb7db7cc4c6634cf1bc545bd2486 114 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 5 109 9.1E-12 T 13-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THITH_02360 bed7185d095d2ab12ab4f600e94d2193 101 Gene3D G3DSA:1.10.760.10 29 99 8.3E-16 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_02360 bed7185d095d2ab12ab4f600e94d2193 101 SUPERFAMILY SSF46626 16 99 3.25E-16 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_04540 1c48398c08b77457fff6b7090294bbce 87 Pfam PF10387 Protein of unknown function (DUF2442) 12 81 3.4E-23 T 13-10-2018 IPR018841 Protein of unknown function DUF2442 THITH_04540 1c48398c08b77457fff6b7090294bbce 87 Gene3D G3DSA:3.30.2020.20 4 76 4.9E-19 T 13-10-2018 THITH_01465 847382f5b3d68b479fce03a6fa86725d 238 SUPERFAMILY SSF54211 1 181 8.6E-47 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_01465 847382f5b3d68b479fce03a6fa86725d 238 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 236 3.6E-115 T 13-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 THITH_01465 847382f5b3d68b479fce03a6fa86725d 238 Pfam PF03725 3' exoribonuclease family, domain 2 160 223 3.4E-11 T 13-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THITH_01465 847382f5b3d68b479fce03a6fa86725d 238 ProSitePatterns PS01277 Ribonuclease PH signature. 116 129 - T 13-10-2018 IPR018336 Ribonuclease PH, conserved site THITH_01465 847382f5b3d68b479fce03a6fa86725d 238 Gene3D G3DSA:3.30.230.70 10 238 8.6E-61 T 13-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THITH_01465 847382f5b3d68b479fce03a6fa86725d 238 SUPERFAMILY SSF55666 153 236 8.64E-24 T 13-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THITH_01465 847382f5b3d68b479fce03a6fa86725d 238 Pfam PF01138 3' exoribonuclease family, domain 1 10 140 7.0E-22 T 13-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 THITH_01465 847382f5b3d68b479fce03a6fa86725d 238 Hamap MF_00564 Ribonuclease PH [rph]. 11 237 44.733 T 13-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 THITH_06910 4aee3b0d1c5bd438c68d2e3929ff3d33 222 Pfam PF03379 CcmB protein 6 219 7.6E-74 T 13-10-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06910 4aee3b0d1c5bd438c68d2e3929ff3d33 222 PIRSF PIRSF002764 1 222 4.3E-80 T 13-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria THITH_06910 4aee3b0d1c5bd438c68d2e3929ff3d33 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 78 101 2.7E-63 T 13-10-2018 THITH_06910 4aee3b0d1c5bd438c68d2e3929ff3d33 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 55 72 2.7E-63 T 13-10-2018 THITH_06910 4aee3b0d1c5bd438c68d2e3929ff3d33 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 103 121 2.7E-63 T 13-10-2018 THITH_06910 4aee3b0d1c5bd438c68d2e3929ff3d33 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 195 218 2.7E-63 T 13-10-2018 THITH_06910 4aee3b0d1c5bd438c68d2e3929ff3d33 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 134 157 2.7E-63 T 13-10-2018 THITH_06910 4aee3b0d1c5bd438c68d2e3929ff3d33 222 PRINTS PR01414 Cytochrome c-type biogenesis protein CcmB signature 29 50 2.7E-63 T 13-10-2018 THITH_06910 4aee3b0d1c5bd438c68d2e3929ff3d33 222 TIGRFAM TIGR01190 ccmB: heme exporter protein CcmB 8 218 2.7E-74 T 13-10-2018 IPR026031 Cytochrome c-type biogenesis protein CcmB, bacteria THITH_01745 637ed5ad3110173b62f4df8cdfb16ecd 115 SUPERFAMILY SSF53850 3 114 3.26E-12 T 13-10-2018 THITH_01745 637ed5ad3110173b62f4df8cdfb16ecd 115 Gene3D G3DSA:3.40.190.10 1 115 2.3E-11 T 13-10-2018 THITH_01220 d30850deec9d7982634f93bbf33d655d 344 Pfam PF00248 Aldo/keto reductase family 16 335 1.6E-71 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain THITH_01220 d30850deec9d7982634f93bbf33d655d 344 SUPERFAMILY SSF51430 1 344 7.07E-106 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily THITH_01220 d30850deec9d7982634f93bbf33d655d 344 Gene3D G3DSA:3.20.20.100 1 344 1.5E-126 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily THITH_14055 9ea2a5ff5f69a1501017346961e4b0dc 172 Hamap MF_01186 LPS-assembly lipoprotein LptE [lptE]. 4 164 20.557 T 13-10-2018 IPR007485 LPS-assembly lipoprotein LptE GO:0019867|GO:0043165 THITH_14055 9ea2a5ff5f69a1501017346961e4b0dc 172 Gene3D G3DSA:3.30.160.150 17 171 9.3E-34 T 13-10-2018 THITH_15765 1558ea9ef2e85648d15162d810c1a1d1 138 Pfam PF02635 DsrE/DsrF-like family 49 138 6.8E-15 T 13-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THITH_15765 1558ea9ef2e85648d15162d810c1a1d1 138 SUPERFAMILY SSF75169 23 138 1.23E-21 T 13-10-2018 IPR027396 DsrEFH-like THITH_15765 1558ea9ef2e85648d15162d810c1a1d1 138 Gene3D G3DSA:3.40.1260.10 21 138 9.7E-29 T 13-10-2018 IPR027396 DsrEFH-like THITH_09830 0e3cce3a9efdbc0fa84596e1b9cc2822 428 Pfam PF07603 Protein of unknown function (DUF1566) 278 420 4.1E-18 T 13-10-2018 IPR011460 Protein of unknown function DUF1566 THITH_09830 0e3cce3a9efdbc0fa84596e1b9cc2822 428 Gene3D G3DSA:2.60.40.10 167 260 6.2E-12 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_09830 0e3cce3a9efdbc0fa84596e1b9cc2822 428 SUPERFAMILY SSF49265 172 258 1.19E-6 T 13-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 THITH_16265 60dbfbd1c89f7b9bf4ace447e167d9be 406 TIGRFAM TIGR00261 traB: TraB family protein 21 399 9.5E-87 T 13-10-2018 IPR005230 Pheromone shutdown, TraB, bacterial/archaeal THITH_16265 60dbfbd1c89f7b9bf4ace447e167d9be 406 Pfam PF01963 TraB family 16 243 1.0E-31 T 13-10-2018 IPR002816 Pheromone shutdown, TraB THITH_03345 a534ee2970e1cd1a6621ee3f82a532e5 94 Gene3D G3DSA:1.10.260.40 36 91 4.8E-6 T 13-10-2018 THITH_02770 88b5846be3569a17f2595754f5c97300 452 Pfam PF01523 Putative modulator of DNA gyrase 36 327 8.0E-55 T 13-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 THITH_02770 88b5846be3569a17f2595754f5c97300 452 SUPERFAMILY SSF111283 16 451 1.44E-122 T 13-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 THITH_02770 88b5846be3569a17f2595754f5c97300 452 Gene3D G3DSA:3.30.2290.10 6 236 3.9E-84 T 13-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal THITH_13680 f8d18a4a0fb4ed7402b257e95a4e84d6 482 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 469 6.1E-226 T 13-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THITH_13680 f8d18a4a0fb4ed7402b257e95a4e84d6 482 SUPERFAMILY SSF48179 177 472 8.16E-123 T 13-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 THITH_13680 f8d18a4a0fb4ed7402b257e95a4e84d6 482 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 169 1.1E-51 T 13-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 THITH_13680 f8d18a4a0fb4ed7402b257e95a4e84d6 482 SMART SM01350 179 469 2.2E-201 T 13-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THITH_13680 f8d18a4a0fb4ed7402b257e95a4e84d6 482 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 179 468 9.0E-124 T 13-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THITH_13680 f8d18a4a0fb4ed7402b257e95a4e84d6 482 Gene3D G3DSA:1.10.1040.10 181 434 6.8E-103 T 13-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 THITH_13680 f8d18a4a0fb4ed7402b257e95a4e84d6 482 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 253 265 - T 13-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THITH_13680 f8d18a4a0fb4ed7402b257e95a4e84d6 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 168 196 7.1E-84 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THITH_13680 f8d18a4a0fb4ed7402b257e95a4e84d6 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 67 96 7.1E-84 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THITH_13680 f8d18a4a0fb4ed7402b257e95a4e84d6 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 7.1E-84 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THITH_13680 f8d18a4a0fb4ed7402b257e95a4e84d6 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 120 145 7.1E-84 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THITH_13680 f8d18a4a0fb4ed7402b257e95a4e84d6 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 249 276 7.1E-84 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THITH_13680 f8d18a4a0fb4ed7402b257e95a4e84d6 482 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 356 378 7.1E-84 T 13-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THITH_13680 f8d18a4a0fb4ed7402b257e95a4e84d6 482 SUPERFAMILY SSF51735 4 177 1.31E-56 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_13680 f8d18a4a0fb4ed7402b257e95a4e84d6 482 PIRSF PIRSF000109 1 477 3.6E-230 T 13-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 THITH_13680 f8d18a4a0fb4ed7402b257e95a4e84d6 482 Gene3D G3DSA:1.20.5.320 435 482 1.5E-24 T 13-10-2018 THITH_13680 f8d18a4a0fb4ed7402b257e95a4e84d6 482 Gene3D G3DSA:3.40.50.720 1 180 2.0E-57 T 13-10-2018 THITH_05695 5ead2ff9452f3a80d4eb395579fdeaef 99 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 40 8.5E-14 T 13-10-2018 THITH_05695 5ead2ff9452f3a80d4eb395579fdeaef 99 SUPERFAMILY SSF46785 2 96 1.03E-15 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_05695 5ead2ff9452f3a80d4eb395579fdeaef 99 Gene3D G3DSA:1.10.10.10 1 98 2.9E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_05695 5ead2ff9452f3a80d4eb395579fdeaef 99 TIGRFAM TIGR04176 MarR_EPS: EPS-associated transcriptional regulator, MarR family 1 95 5.8E-44 T 13-10-2018 IPR026433 EPS-associated transcriptional regulator, MarR family THITH_02120 9d4a1c65e1e60bc98e648b7ffa9b3b5a 198 SUPERFAMILY SSF89155 1 193 4.06E-43 T 13-10-2018 IPR036411 TorD-like superfamily THITH_02120 9d4a1c65e1e60bc98e648b7ffa9b3b5a 198 Pfam PF02613 Nitrate reductase delta subunit 52 163 1.2E-28 T 13-10-2018 IPR020945 DMSO/Nitrate reductase chaperone THITH_02120 9d4a1c65e1e60bc98e648b7ffa9b3b5a 198 Gene3D G3DSA:1.10.3480.10 7 195 3.6E-40 T 13-10-2018 THITH_15625 ebbc6c6a76fc9260ea9cf59365367e3e 281 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 122 169 1.0E-6 T 13-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase THITH_15625 ebbc6c6a76fc9260ea9cf59365367e3e 281 SUPERFAMILY SSF53223 4 103 1.44E-30 T 13-10-2018 THITH_15625 ebbc6c6a76fc9260ea9cf59365367e3e 281 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 3 277 32.377 T 13-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 THITH_15625 ebbc6c6a76fc9260ea9cf59365367e3e 281 Gene3D G3DSA:3.40.50.720 126 239 2.7E-26 T 13-10-2018 THITH_15625 ebbc6c6a76fc9260ea9cf59365367e3e 281 SUPERFAMILY SSF51735 104 275 1.64E-35 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_15625 ebbc6c6a76fc9260ea9cf59365367e3e 281 Gene3D G3DSA:3.40.50.10860 3 125 2.2E-40 T 13-10-2018 THITH_15625 ebbc6c6a76fc9260ea9cf59365367e3e 281 Gene3D G3DSA:3.40.50.10860 240 279 9.0E-7 T 13-10-2018 THITH_15625 ebbc6c6a76fc9260ea9cf59365367e3e 281 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 8 90 4.5E-23 T 13-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 THITH_15625 ebbc6c6a76fc9260ea9cf59365367e3e 281 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 5 277 4.0E-76 T 13-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 THITH_14610 350998c968b35e0ace45b9efe5485334 152 TIGRFAM TIGR04430 OM_asym_MlaD: outer membrane lipid asymmetry maintenance protein MlaD 4 147 7.9E-51 T 13-10-2018 IPR030970 Probable phospholipid ABC transporter-binding protein MlaD GO:0015914 THITH_14610 350998c968b35e0ace45b9efe5485334 152 Pfam PF02470 MlaD protein 38 117 8.1E-24 T 13-10-2018 IPR003399 Mce/MlaD THITH_11145 de5b3f0eba3e616570e7e080c89571af 340 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1 167 0.0024 T 13-10-2018 THITH_11145 de5b3f0eba3e616570e7e080c89571af 340 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 230 5.2E-28 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 THITH_11145 de5b3f0eba3e616570e7e080c89571af 340 Gene3D G3DSA:3.40.50.720 1 329 2.6E-86 T 13-10-2018 THITH_11145 de5b3f0eba3e616570e7e080c89571af 340 SUPERFAMILY SSF51735 2 322 2.45E-63 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_06280 bc618f71a30be694106d28ca96a3c469 276 SMART SM00650 21 192 8.3E-80 T 13-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 THITH_06280 bc618f71a30be694106d28ca96a3c469 276 Gene3D G3DSA:3.40.50.150 2 196 9.6E-65 T 13-10-2018 THITH_06280 bc618f71a30be694106d28ca96a3c469 276 SUPERFAMILY SSF53335 5 256 4.18E-70 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_06280 bc618f71a30be694106d28ca96a3c469 276 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 37 64 - T 13-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 THITH_06280 bc618f71a30be694106d28ca96a3c469 276 Pfam PF00398 Ribosomal RNA adenine dimethylase 7 237 6.8E-60 T 13-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm THITH_06280 bc618f71a30be694106d28ca96a3c469 276 Gene3D G3DSA:1.10.8.100 198 264 6.4E-16 T 13-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 THITH_06280 bc618f71a30be694106d28ca96a3c469 276 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 6 256 2.8E-77 T 13-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 THITH_06280 bc618f71a30be694106d28ca96a3c469 276 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 5 259 53.777 T 13-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 THITH_00255 2887fc75d8f408f3ac54db9dac5b2606 397 SUPERFAMILY SSF53756 130 386 1.7E-17 T 13-10-2018 THITH_00255 2887fc75d8f408f3ac54db9dac5b2606 397 Gene3D G3DSA:3.40.50.12580 190 374 8.9E-36 T 13-10-2018 THITH_00255 2887fc75d8f408f3ac54db9dac5b2606 397 Pfam PF04464 CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase 45 386 4.9E-40 T 13-10-2018 IPR007554 CDP-glycerol glycerophosphotransferase GO:0016020|GO:0047355 THITH_00255 2887fc75d8f408f3ac54db9dac5b2606 397 Gene3D G3DSA:3.40.50.11820 44 381 8.9E-36 T 13-10-2018 THITH_03300 2facd8e3d7e22f0df793b0b843792de3 135 Pfam PF03928 Haem-degrading 1 126 5.3E-30 T 13-10-2018 IPR005624 Haem-degrading THITH_03300 2facd8e3d7e22f0df793b0b843792de3 135 SUPERFAMILY SSF143744 1 129 7.45E-38 T 13-10-2018 IPR038084 GlcG-like domain superfamily THITH_03300 2facd8e3d7e22f0df793b0b843792de3 135 Gene3D G3DSA:3.30.450.150 1 133 3.4E-45 T 13-10-2018 IPR038084 GlcG-like domain superfamily THITH_16525 b3f0c1a8d752fb2cb665421b00a2a7a2 494 Gene3D G3DSA:1.20.210.10 15 488 7.0E-191 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_16525 b3f0c1a8d752fb2cb665421b00a2a7a2 494 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 26 455 1.0E-110 T 13-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_16525 b3f0c1a8d752fb2cb665421b00a2a7a2 494 SUPERFAMILY SSF81442 22 481 1.44E-120 T 13-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_16525 b3f0c1a8d752fb2cb665421b00a2a7a2 494 TIGRFAM TIGR00780 ccoN: cytochrome c oxidase, cbb3-type, subunit I 21 484 1.6E-210 T 13-10-2018 IPR004677 Cytochrome c oxidase cbb3-type, subunit I GO:0004129|GO:0045278|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 THITH_16525 b3f0c1a8d752fb2cb665421b00a2a7a2 494 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 218 273 - T 13-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_03605 67c1096b0252af685b63320ce0a95ea8 300 SUPERFAMILY SSF103247 36 137 3.66E-7 T 13-10-2018 IPR035923 TT1751-like domain superfamily THITH_07550 48bb74d212aab6a91b6e925dc720b747 230 SUPERFAMILY SSF53335 33 220 1.1E-45 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_07550 48bb74d212aab6a91b6e925dc720b747 230 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 3 224 38.638 T 13-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 THITH_07550 48bb74d212aab6a91b6e925dc720b747 230 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 34 221 4.3E-63 T 13-10-2018 THITH_07550 48bb74d212aab6a91b6e925dc720b747 230 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 33 222 1.1E-65 T 13-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 THITH_07550 48bb74d212aab6a91b6e925dc720b747 230 Gene3D G3DSA:3.40.50.150 8 225 1.7E-77 T 13-10-2018 THITH_05790 60d22899493a86b4f35375dad56a2b8b 358 SUPERFAMILY SSF88713 140 347 1.62E-12 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THITH_05790 60d22899493a86b4f35375dad56a2b8b 358 Gene3D G3DSA:3.20.20.370 68 357 8.2E-17 T 13-10-2018 THITH_02350 94717d3de6a0454c93b7888b6190c6db 67 Pfam PF04325 Protein of unknown function (DUF465) 14 57 2.6E-11 T 13-10-2018 IPR007420 Protein of unknown function DUF465 THITH_15610 ce0da43639cbbd5f7661714b18502e59 188 Gene3D G3DSA:3.90.870.10 2 183 5.7E-53 T 13-10-2018 THITH_15610 ce0da43639cbbd5f7661714b18502e59 188 Hamap MF_01852 Threonylcarbamoyl-AMP synthase [tsaC]. 3 183 34.188 T 13-10-2018 IPR023535 Threonylcarbamoyl-AMP synthase GO:0002949|GO:0005524 THITH_15610 ce0da43639cbbd5f7661714b18502e59 188 Pfam PF01300 Telomere recombination 12 179 2.9E-41 T 13-10-2018 IPR006070 YrdC-like domain GO:0003725 THITH_15610 ce0da43639cbbd5f7661714b18502e59 188 SUPERFAMILY SSF55821 6 182 2.47E-49 T 13-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily THITH_15975 7ed558ece7842fe89e331d167fe4aafc 681 SUPERFAMILY SSF47226 12 125 6.28E-5 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 THITH_15975 7ed558ece7842fe89e331d167fe4aafc 681 SUPERFAMILY SSF47226 409 517 1.06E-7 T 13-10-2018 IPR036641 HPT domain superfamily GO:0000160 THITH_12925 3a0412e2ca0e5fe3e680bd7616906773 484 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 6 472 18.598 T 13-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 THITH_12925 3a0412e2ca0e5fe3e680bd7616906773 484 Pfam PF00361 Proton-conducting membrane transporter 125 420 1.0E-74 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12925 3a0412e2ca0e5fe3e680bd7616906773 484 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 149 170 9.2E-10 T 13-10-2018 THITH_12925 3a0412e2ca0e5fe3e680bd7616906773 484 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 73 98 9.2E-10 T 13-10-2018 THITH_12925 3a0412e2ca0e5fe3e680bd7616906773 484 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 217 238 9.2E-10 T 13-10-2018 THITH_12925 3a0412e2ca0e5fe3e680bd7616906773 484 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 414 433 9.2E-10 T 13-10-2018 THITH_12925 3a0412e2ca0e5fe3e680bd7616906773 484 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 9 471 1.5E-148 T 13-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 THITH_10025 fcc32d36216c23658cdee51c1c6dfd54 284 Gene3D G3DSA:1.25.40.10 22 284 3.4E-49 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_10025 fcc32d36216c23658cdee51c1c6dfd54 284 SMART SM00671 104 139 20.0 T 13-10-2018 IPR006597 Sel1-like repeat THITH_10025 fcc32d36216c23658cdee51c1c6dfd54 284 SMART SM00671 217 252 1.4E-5 T 13-10-2018 IPR006597 Sel1-like repeat THITH_10025 fcc32d36216c23658cdee51c1c6dfd54 284 SMART SM00671 180 216 2.0E-5 T 13-10-2018 IPR006597 Sel1-like repeat THITH_10025 fcc32d36216c23658cdee51c1c6dfd54 284 SMART SM00671 34 67 150.0 T 13-10-2018 IPR006597 Sel1-like repeat THITH_10025 fcc32d36216c23658cdee51c1c6dfd54 284 SMART SM00671 68 103 7.4E-8 T 13-10-2018 IPR006597 Sel1-like repeat THITH_10025 fcc32d36216c23658cdee51c1c6dfd54 284 SUPERFAMILY SSF81901 46 148 1.31E-19 T 13-10-2018 THITH_10025 fcc32d36216c23658cdee51c1c6dfd54 284 SUPERFAMILY SSF81901 136 255 8.24E-17 T 13-10-2018 THITH_10025 fcc32d36216c23658cdee51c1c6dfd54 284 Pfam PF08238 Sel1 repeat 69 103 6.5E-6 T 13-10-2018 IPR006597 Sel1-like repeat THITH_10025 fcc32d36216c23658cdee51c1c6dfd54 284 Pfam PF08238 Sel1 repeat 182 216 9.3E-6 T 13-10-2018 IPR006597 Sel1-like repeat THITH_10025 fcc32d36216c23658cdee51c1c6dfd54 284 Pfam PF08238 Sel1 repeat 220 252 5.0E-4 T 13-10-2018 IPR006597 Sel1-like repeat THITH_10025 fcc32d36216c23658cdee51c1c6dfd54 284 Pfam PF08238 Sel1 repeat 49 67 0.1 T 13-10-2018 IPR006597 Sel1-like repeat THITH_10025 fcc32d36216c23658cdee51c1c6dfd54 284 Pfam PF08238 Sel1 repeat 109 133 0.0033 T 13-10-2018 IPR006597 Sel1-like repeat THITH_09055 ce1381cd8a99254fb6a10d573a481927 526 Gene3D G3DSA:3.40.5.90 1 79 1.0E-30 T 13-10-2018 THITH_09055 ce1381cd8a99254fb6a10d573a481927 526 SUPERFAMILY SSF51395 138 508 2.44E-100 T 13-10-2018 THITH_09055 ce1381cd8a99254fb6a10d573a481927 526 SMART SM00704 9 46 4.3E-11 T 13-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 THITH_09055 ce1381cd8a99254fb6a10d573a481927 526 SMART SM00704 47 82 4.3E-5 T 13-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 THITH_09055 ce1381cd8a99254fb6a10d573a481927 526 Pfam PF01645 Conserved region in glutamate synthase 183 488 9.7E-87 T 13-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 THITH_09055 ce1381cd8a99254fb6a10d573a481927 526 Pfam PF09360 Iron-binding zinc finger CDGSH type 58 76 1.1E-7 T 13-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 THITH_09055 ce1381cd8a99254fb6a10d573a481927 526 Pfam PF09360 Iron-binding zinc finger CDGSH type 10 40 9.1E-11 T 13-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 THITH_09055 ce1381cd8a99254fb6a10d573a481927 526 Gene3D G3DSA:3.20.20.70 181 519 5.4E-98 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_05085 50bd6986755aa145b73ca1e2b8dd4c3c 130 Gene3D G3DSA:3.30.310.70 1 127 4.5E-47 T 13-10-2018 IPR035923 TT1751-like domain superfamily THITH_05085 50bd6986755aa145b73ca1e2b8dd4c3c 130 SUPERFAMILY SSF103247 5 123 3.01E-37 T 13-10-2018 IPR035923 TT1751-like domain superfamily THITH_05085 50bd6986755aa145b73ca1e2b8dd4c3c 130 PIRSF PIRSF021774 1 129 2.4E-43 T 13-10-2018 IPR016796 Uncharacterised conserved protein UCP021774 THITH_05085 50bd6986755aa145b73ca1e2b8dd4c3c 130 Pfam PF03625 Domain of unknown function DUF302 34 97 1.2E-28 T 13-10-2018 IPR005180 Domain of unknown function DUF302 THITH_07050 6550387fe6914dd9f71d30a043e2b393 331 Gene3D G3DSA:3.40.50.720 6 292 4.3E-69 T 13-10-2018 THITH_07050 6550387fe6914dd9f71d30a043e2b393 331 Gene3D G3DSA:3.30.360.10 123 305 4.3E-69 T 13-10-2018 THITH_07050 6550387fe6914dd9f71d30a043e2b393 331 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 122 6.3E-30 T 13-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 THITH_07050 6550387fe6914dd9f71d30a043e2b393 331 SUPERFAMILY SSF51735 3 162 1.8E-43 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_07050 6550387fe6914dd9f71d30a043e2b393 331 SUPERFAMILY SSF55347 150 276 6.32E-13 T 13-10-2018 THITH_17040 353b2365e018081594e440172e3c58cd 188 Pfam PF01949 Protein of unknown function DUF99 6 179 1.7E-56 T 13-10-2018 IPR002802 Protein of unknown function DUF99 THITH_17040 353b2365e018081594e440172e3c58cd 188 PIRSF PIRSF006380 1 187 5.5E-55 T 13-10-2018 IPR002802 Protein of unknown function DUF99 THITH_17040 353b2365e018081594e440172e3c58cd 188 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 67 182 1.0E-31 T 13-10-2018 IPR002802 Protein of unknown function DUF99 THITH_17040 353b2365e018081594e440172e3c58cd 188 Gene3D G3DSA:3.30.2170.10 2 188 1.5E-55 T 13-10-2018 THITH_17040 353b2365e018081594e440172e3c58cd 188 Hamap MF_00582 UPF0215 protein . 6 181 30.702 T 13-10-2018 IPR002802 Protein of unknown function DUF99 THITH_00470 b22051ec81d66718fdc8351e44f2c991 215 PIRSF PIRSF000495 2 213 1.6E-58 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 THITH_00470 b22051ec81d66718fdc8351e44f2c991 215 SUPERFAMILY SSF52317 3 211 6.01E-52 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_00470 b22051ec81d66718fdc8351e44f2c991 215 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 210 1.8E-57 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 THITH_00470 b22051ec81d66718fdc8351e44f2c991 215 Gene3D G3DSA:3.40.50.880 1 213 7.8E-63 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_00470 b22051ec81d66718fdc8351e44f2c991 215 Pfam PF00117 Glutamine amidotransferase class-I 6 208 1.9E-15 T 13-10-2018 IPR017926 Glutamine amidotransferase THITH_00470 b22051ec81d66718fdc8351e44f2c991 215 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 211 32.39 T 13-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 THITH_13875 ce7a57c1f55580067b5aaeafdf87196a 152 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 2 144 4.4E-35 T 13-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 THITH_13875 ce7a57c1f55580067b5aaeafdf87196a 152 Gene3D G3DSA:3.30.479.10 1 91 5.2E-24 T 13-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 THITH_13875 ce7a57c1f55580067b5aaeafdf87196a 152 Gene3D G3DSA:3.30.479.10 92 151 7.1E-11 T 13-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 THITH_13875 ce7a57c1f55580067b5aaeafdf87196a 152 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 3 115 6.8E-28 T 13-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 THITH_13875 ce7a57c1f55580067b5aaeafdf87196a 152 SUPERFAMILY SSF55620 1 145 1.78E-39 T 13-10-2018 THITH_07985 19e56756dff001c0715fbccbd8f067f5 242 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 12 232 2.6E-54 T 13-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_07985 19e56756dff001c0715fbccbd8f067f5 242 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 63 76 - T 13-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_07985 19e56756dff001c0715fbccbd8f067f5 242 SMART SM00934 11 232 9.7E-89 T 13-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_07985 19e56756dff001c0715fbccbd8f067f5 242 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 10 231 1.0E-43 T 13-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_07985 19e56756dff001c0715fbccbd8f067f5 242 Gene3D G3DSA:3.20.20.70 5 239 2.4E-81 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_07985 19e56756dff001c0715fbccbd8f067f5 242 SUPERFAMILY SSF51366 10 235 5.3E-72 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 THITH_07985 19e56756dff001c0715fbccbd8f067f5 242 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 9 237 36.345 T 13-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_07075 d3fb034678434104edf29ef3b4d619fc 554 SUPERFAMILY SSF52317 288 543 5.0E-88 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_07075 d3fb034678434104edf29ef3b4d619fc 554 TIGRFAM TIGR00337 PyrG: CTP synthase 2 537 6.5E-248 T 13-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 THITH_07075 d3fb034678434104edf29ef3b4d619fc 554 Pfam PF06418 CTP synthase N-terminus 3 265 3.4E-125 T 13-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 THITH_07075 d3fb034678434104edf29ef3b4d619fc 554 Pfam PF00117 Glutamine amidotransferase class-I 300 536 1.6E-57 T 13-10-2018 IPR017926 Glutamine amidotransferase THITH_07075 d3fb034678434104edf29ef3b4d619fc 554 Gene3D G3DSA:3.40.50.880 285 547 4.6E-105 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_07075 d3fb034678434104edf29ef3b4d619fc 554 Gene3D G3DSA:3.40.50.300 1 283 1.8E-131 T 13-10-2018 THITH_07075 d3fb034678434104edf29ef3b4d619fc 554 Hamap MF_01227 CTP synthase [pyrG]. 2 542 51.638 T 13-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 THITH_07075 d3fb034678434104edf29ef3b4d619fc 554 SUPERFAMILY SSF52540 1 268 1.03E-122 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_07780 0c6b5d7baf4695654486a396565c0833 106 Gene3D G3DSA:2.60.120.10 1 106 2.0E-17 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_07780 0c6b5d7baf4695654486a396565c0833 106 Pfam PF12973 ChrR Cupin-like domain 17 99 5.3E-10 T 13-10-2018 IPR025979 ChrR-like cupin domain THITH_07780 0c6b5d7baf4695654486a396565c0833 106 SUPERFAMILY SSF51182 2 99 1.22E-14 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily THITH_15755 01db17c1151670d38f4f6df30ffd2332 343 SUPERFAMILY SSF56112 13 321 3.21E-45 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily THITH_15755 01db17c1151670d38f4f6df30ffd2332 343 Gene3D G3DSA:3.90.1200.10 100 340 2.5E-67 T 13-10-2018 THITH_15755 01db17c1151670d38f4f6df30ffd2332 343 Pfam PF01636 Phosphotransferase enzyme family 33 273 4.5E-26 T 13-10-2018 IPR002575 Aminoglycoside phosphotransferase THITH_15755 01db17c1151670d38f4f6df30ffd2332 343 Gene3D G3DSA:3.30.200.20 11 99 1.1E-22 T 13-10-2018 THITH_16410 3102be8e5e121af523298d9f43098704 402 SUPERFAMILY SSF103473 4 385 7.06E-42 T 13-10-2018 IPR036259 MFS transporter superfamily THITH_16410 3102be8e5e121af523298d9f43098704 402 Pfam PF07690 Major Facilitator Superfamily 19 186 1.4E-17 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THITH_16410 3102be8e5e121af523298d9f43098704 402 Pfam PF07690 Major Facilitator Superfamily 211 394 1.1E-16 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THITH_16410 3102be8e5e121af523298d9f43098704 402 PRINTS PR01035 Tetracycline resistance protein signature 4 20 2.9E-5 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 THITH_16410 3102be8e5e121af523298d9f43098704 402 PRINTS PR01035 Tetracycline resistance protein signature 131 153 2.9E-5 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 THITH_16410 3102be8e5e121af523298d9f43098704 402 PRINTS PR01035 Tetracycline resistance protein signature 361 380 2.9E-5 T 13-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 THITH_16410 3102be8e5e121af523298d9f43098704 402 Gene3D G3DSA:1.20.1250.20 202 390 1.2E-22 T 13-10-2018 THITH_16410 3102be8e5e121af523298d9f43098704 402 Gene3D G3DSA:1.20.1250.20 1 187 3.3E-19 T 13-10-2018 THITH_12700 a8162f1841cdfd9783f813584013174b 219 Gene3D G3DSA:1.10.760.10 62 160 6.6E-10 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_12700 a8162f1841cdfd9783f813584013174b 219 SUPERFAMILY SSF46626 78 152 4.05E-12 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_12700 a8162f1841cdfd9783f813584013174b 219 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 80 150 2.1E-11 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_10240 8aaa50073ec20e3a195bd7288c844161 422 SUPERFAMILY SSF56300 4 279 1.21E-53 T 13-10-2018 THITH_10240 8aaa50073ec20e3a195bd7288c844161 422 Gene3D G3DSA:3.60.21.10 2 242 1.6E-51 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like THITH_10240 8aaa50073ec20e3a195bd7288c844161 422 Pfam PF00149 Calcineurin-like phosphoesterase 4 199 4.3E-12 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THITH_10240 8aaa50073ec20e3a195bd7288c844161 422 PIRSF PIRSF033091 2 418 2.7E-104 T 13-10-2018 IPR014576 Predicted phosphoesterase, YhaO type THITH_15915 538b6001d5169f5f8bcc3c77847f895b 299 ProSitePatterns PS01057 SAICAR synthetase signature 1. 109 123 - T 13-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THITH_15915 538b6001d5169f5f8bcc3c77847f895b 299 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 16 295 7.1E-73 T 13-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 THITH_15915 538b6001d5169f5f8bcc3c77847f895b 299 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 13 296 25.894 T 13-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THITH_15915 538b6001d5169f5f8bcc3c77847f895b 299 Gene3D G3DSA:3.30.200.20 4 107 2.1E-29 T 13-10-2018 THITH_15915 538b6001d5169f5f8bcc3c77847f895b 299 ProSitePatterns PS01058 SAICAR synthetase signature 2. 208 216 - T 13-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THITH_15915 538b6001d5169f5f8bcc3c77847f895b 299 SUPERFAMILY SSF56104 6 296 3.01E-100 T 13-10-2018 THITH_15915 538b6001d5169f5f8bcc3c77847f895b 299 Gene3D G3DSA:3.30.470.20 108 252 8.5E-59 T 13-10-2018 THITH_15915 538b6001d5169f5f8bcc3c77847f895b 299 Pfam PF01259 SAICAR synthetase 16 271 4.0E-97 T 13-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 THITH_10095 91cb1dd465f6b989df5ab88e3c3b8882 474 SUPERFAMILY SSF51735 147 277 1.3E-13 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_10095 91cb1dd465f6b989df5ab88e3c3b8882 474 Pfam PF13727 CoA-binding domain 67 245 6.2E-34 T 13-10-2018 THITH_10095 91cb1dd465f6b989df5ab88e3c3b8882 474 TIGRFAM TIGR03023 WcaJ_sugtrans: undecaprenyl-phosphate glucose phosphotransferase 25 474 2.0E-160 T 13-10-2018 IPR017473 Undecaprenyl-phosphate glucose phosphotransferase, WcaJ MetaCyc: PWY-6655|MetaCyc: PWY-6658 THITH_10095 91cb1dd465f6b989df5ab88e3c3b8882 474 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 24 474 9.0E-147 T 13-10-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase THITH_10095 91cb1dd465f6b989df5ab88e3c3b8882 474 Gene3D G3DSA:3.40.50.720 145 268 3.6E-22 T 13-10-2018 THITH_10095 91cb1dd465f6b989df5ab88e3c3b8882 474 Pfam PF02397 Bacterial sugar transferase 281 465 2.0E-62 T 13-10-2018 IPR003362 Bacterial sugar transferase THITH_13570 81c8a03ad06554ab396059bb29117267 310 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 47 71 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 THITH_13570 81c8a03ad06554ab396059bb29117267 310 Gene3D G3DSA:3.40.1190.20 1 310 1.3E-108 T 13-10-2018 IPR029056 Ribokinase-like THITH_13570 81c8a03ad06554ab396059bb29117267 310 Pfam PF00294 pfkB family carbohydrate kinase 36 290 2.0E-39 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB THITH_13570 81c8a03ad06554ab396059bb29117267 310 SUPERFAMILY SSF53613 2 296 2.03E-64 T 13-10-2018 IPR029056 Ribokinase-like THITH_14930 b55d905d9d08eb40600d214d1ef3252c 393 Gene3D G3DSA:1.10.3210.10 11 388 7.4E-135 T 13-10-2018 THITH_14930 b55d905d9d08eb40600d214d1ef3252c 393 Pfam PF01966 HD domain 75 205 2.2E-14 T 13-10-2018 IPR006674 HD domain THITH_14930 b55d905d9d08eb40600d214d1ef3252c 393 SUPERFAMILY SSF109604 26 388 4.12E-90 T 13-10-2018 THITH_14930 b55d905d9d08eb40600d214d1ef3252c 393 Pfam PF13286 Phosphohydrolase-associated domain 292 385 5.0E-29 T 13-10-2018 IPR026875 Phosphohydrolase-associated domain THITH_14930 b55d905d9d08eb40600d214d1ef3252c 393 SMART SM00471 71 215 4.3E-10 T 13-10-2018 IPR003607 HD/PDEase domain THITH_14930 b55d905d9d08eb40600d214d1ef3252c 393 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 15 387 38.251 T 13-10-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 THITH_14930 b55d905d9d08eb40600d214d1ef3252c 393 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 38 171 4.5E-57 T 13-10-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 THITH_05710 7a3f94e6f46d747e79c465f5891dab73 383 Gene3D G3DSA:3.40.50.2000 3 361 1.4E-152 T 13-10-2018 THITH_05710 7a3f94e6f46d747e79c465f5891dab73 383 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 21 364 2.7E-126 T 13-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 THITH_05710 7a3f94e6f46d747e79c465f5891dab73 383 SUPERFAMILY SSF53756 2 366 5.71E-140 T 13-10-2018 THITH_05710 7a3f94e6f46d747e79c465f5891dab73 383 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 1 366 3.6E-161 T 13-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 THITH_05710 7a3f94e6f46d747e79c465f5891dab73 383 Gene3D G3DSA:3.40.50.2000 187 351 1.4E-152 T 13-10-2018 THITH_04755 b007e1ddcb25aabc604eecf80e24a88c 90 SUPERFAMILY SSF55729 1 72 2.76E-9 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_04755 b007e1ddcb25aabc604eecf80e24a88c 90 Gene3D G3DSA:3.40.630.30 1 87 4.6E-8 T 13-10-2018 THITH_09315 859543809dbee647f6dce9f34412e1cf 284 Gene3D G3DSA:3.100.10.20 29 100 1.8E-8 T 13-10-2018 THITH_09315 859543809dbee647f6dce9f34412e1cf 284 Pfam PF01867 CRISPR associated protein Cas1 30 122 3.3E-10 T 13-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THITH_02780 9cd8a008ff8d52f60a576b5e97eb388a 219 Pfam PF00551 Formyl transferase 1 177 5.1E-55 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THITH_02780 9cd8a008ff8d52f60a576b5e97eb388a 219 Gene3D G3DSA:3.40.50.170 1 203 9.8E-77 T 13-10-2018 THITH_02780 9cd8a008ff8d52f60a576b5e97eb388a 219 SUPERFAMILY SSF53328 1 196 2.62E-61 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THITH_02780 9cd8a008ff8d52f60a576b5e97eb388a 219 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 1 185 3.1E-69 T 13-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 THITH_02780 9cd8a008ff8d52f60a576b5e97eb388a 219 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 1 183 28.559 T 13-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 THITH_14585 d704e80a7195c70d384a109ec3de6548 352 Gene3D G3DSA:3.20.20.70 1 350 5.7E-164 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_14585 d704e80a7195c70d384a109ec3de6548 352 Pfam PF00793 DAHP synthetase I family 42 337 6.9E-100 T 13-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 THITH_14585 d704e80a7195c70d384a109ec3de6548 352 PIRSF PIRSF001361 1 352 9.2E-162 T 13-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 THITH_14585 d704e80a7195c70d384a109ec3de6548 352 SUPERFAMILY SSF51569 7 348 1.36E-136 T 13-10-2018 THITH_14585 d704e80a7195c70d384a109ec3de6548 352 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 6 349 9.6E-159 T 13-10-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 THITH_05060 5df5a9891d3b6af59d06e690cae8a825 231 Pfam PF00535 Glycosyl transferase family 2 11 107 1.4E-17 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THITH_05060 5df5a9891d3b6af59d06e690cae8a825 231 Gene3D G3DSA:3.90.550.10 2 213 2.1E-29 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_05060 5df5a9891d3b6af59d06e690cae8a825 231 SUPERFAMILY SSF53448 6 191 4.41E-32 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_05060 5df5a9891d3b6af59d06e690cae8a825 231 TIGRFAM TIGR04283 glyco_like_mftF: transferase 2, rSAM/selenodomain-associated 10 230 7.3E-79 T 13-10-2018 IPR026461 Transferase 2, rSAM/selenodomain-associated THITH_00360 6863ce674edd7dad58bc2ff4dec1973a 296 Gene3D G3DSA:3.90.550.10 1 221 6.3E-48 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_00360 6863ce674edd7dad58bc2ff4dec1973a 296 Pfam PF00535 Glycosyl transferase family 2 11 159 6.8E-28 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THITH_00360 6863ce674edd7dad58bc2ff4dec1973a 296 SUPERFAMILY SSF53448 6 238 8.81E-42 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_06150 5c04520dd26d3a01c0fec910e98d4359 360 Pfam PF01565 FAD binding domain 16 143 1.5E-20 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THITH_06150 5c04520dd26d3a01c0fec910e98d4359 360 Gene3D G3DSA:3.30.465.10 59 180 9.2E-35 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 THITH_06150 5c04520dd26d3a01c0fec910e98d4359 360 SUPERFAMILY SSF55103 195 359 1.96E-15 T 13-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 THITH_06150 5c04520dd26d3a01c0fec910e98d4359 360 SUPERFAMILY SSF56176 17 181 2.85E-33 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 THITH_10905 def5c7623e2ba752f3e3d1036ee16f48 179 SMART SM00506 10 139 8.0E-40 T 13-10-2018 IPR002589 Macro domain THITH_10905 def5c7623e2ba752f3e3d1036ee16f48 179 Gene3D G3DSA:3.40.220.10 2 173 5.8E-58 T 13-10-2018 THITH_10905 def5c7623e2ba752f3e3d1036ee16f48 179 SUPERFAMILY SSF52949 3 171 1.16E-53 T 13-10-2018 THITH_10905 def5c7623e2ba752f3e3d1036ee16f48 179 Pfam PF01661 Macro domain 28 139 2.7E-36 T 13-10-2018 IPR002589 Macro domain THITH_00695 4c3c558322561587b8e2547139e5a85f 269 SUPERFAMILY SSF53335 21 212 1.66E-19 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_00695 4c3c558322561587b8e2547139e5a85f 269 Pfam PF13649 Methyltransferase domain 52 146 4.9E-9 T 13-10-2018 THITH_00695 4c3c558322561587b8e2547139e5a85f 269 Gene3D G3DSA:3.40.50.150 15 212 9.3E-19 T 13-10-2018 THITH_16750 66f5fc31e0d0965dc6bc42c553f6cc8b 160 Pfam PF00571 CBS domain 93 146 5.6E-13 T 13-10-2018 IPR000644 CBS domain THITH_16750 66f5fc31e0d0965dc6bc42c553f6cc8b 160 Pfam PF00571 CBS domain 3 58 7.8E-16 T 13-10-2018 IPR000644 CBS domain THITH_16750 66f5fc31e0d0965dc6bc42c553f6cc8b 160 SUPERFAMILY SSF54631 1 146 4.04E-34 T 13-10-2018 THITH_16750 66f5fc31e0d0965dc6bc42c553f6cc8b 160 Gene3D G3DSA:3.10.580.10 1 149 1.2E-37 T 13-10-2018 THITH_16750 66f5fc31e0d0965dc6bc42c553f6cc8b 160 SMART SM00116 10 58 1.1E-11 T 13-10-2018 IPR000644 CBS domain THITH_16750 66f5fc31e0d0965dc6bc42c553f6cc8b 160 SMART SM00116 100 147 1.5E-12 T 13-10-2018 IPR000644 CBS domain THITH_16675 999183d165af975de0053255fea334df 305 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 145 264 2.6E-34 T 13-10-2018 IPR028973 PhnB-like THITH_16675 999183d165af975de0053255fea334df 305 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 6 133 2.7E-33 T 13-10-2018 IPR028973 PhnB-like THITH_16675 999183d165af975de0053255fea334df 305 Gene3D G3DSA:3.10.180.70 144 305 1.6E-52 T 13-10-2018 THITH_16675 999183d165af975de0053255fea334df 305 Gene3D G3DSA:3.10.180.10 4 143 5.6E-45 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THITH_16675 999183d165af975de0053255fea334df 305 SUPERFAMILY SSF54593 6 133 4.54E-31 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THITH_16675 999183d165af975de0053255fea334df 305 SUPERFAMILY SSF54593 156 302 2.44E-36 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THITH_14505 f24b10af5ebf0b10bc0804c2423abf43 310 Gene3D G3DSA:1.10.150.170 113 215 6.6E-100 T 13-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 THITH_14505 f24b10af5ebf0b10bc0804c2423abf43 310 SUPERFAMILY SSF81799 115 214 1.57E-36 T 13-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 THITH_14505 f24b10af5ebf0b10bc0804c2423abf43 310 Gene3D G3DSA:3.40.50.150 9 307 6.6E-100 T 13-10-2018 THITH_14505 f24b10af5ebf0b10bc0804c2423abf43 310 SUPERFAMILY SSF53335 6 307 2.58E-41 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_14505 f24b10af5ebf0b10bc0804c2423abf43 310 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 1 307 3.2E-106 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 THITH_14505 f24b10af5ebf0b10bc0804c2423abf43 310 Pfam PF01795 MraW methylase family 5 307 9.3E-105 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 THITH_14505 f24b10af5ebf0b10bc0804c2423abf43 310 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 6 309 37.689 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 THITH_14505 f24b10af5ebf0b10bc0804c2423abf43 310 PIRSF PIRSF004486 1 309 8.4E-100 T 13-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 THITH_15320 b59483912f4f8a18f1bb98be85ff51bb 151 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 1 151 1.4E-53 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 THITH_15320 b59483912f4f8a18f1bb98be85ff51bb 151 Pfam PF00364 Biotin-requiring enzyme 77 150 1.9E-21 T 13-10-2018 IPR000089 Biotin/lipoyl attachment THITH_15320 b59483912f4f8a18f1bb98be85ff51bb 151 SUPERFAMILY SSF51230 76 151 1.28E-24 T 13-10-2018 IPR011053 Single hybrid motif THITH_15320 b59483912f4f8a18f1bb98be85ff51bb 151 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 107 124 - T 13-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THITH_15320 b59483912f4f8a18f1bb98be85ff51bb 151 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 80 93 6.0E-17 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 THITH_15320 b59483912f4f8a18f1bb98be85ff51bb 151 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 112 125 6.0E-17 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 THITH_15320 b59483912f4f8a18f1bb98be85ff51bb 151 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 97 111 6.0E-17 T 13-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 THITH_15320 b59483912f4f8a18f1bb98be85ff51bb 151 Gene3D G3DSA:2.40.50.100 73 151 2.8E-30 T 13-10-2018 THITH_12065 fee418a097c7ce0be07789d835d37d80 257 Hamap MF_00057 8-amino-3,8-dideoxy-manno-octulosonate cytidylyltransferase [kdsB]. 4 252 37.752 T 13-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 THITH_12065 fee418a097c7ce0be07789d835d37d80 257 SUPERFAMILY SSF53448 6 251 1.98E-56 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_12065 fee418a097c7ce0be07789d835d37d80 257 Pfam PF02348 Cytidylyltransferase 7 222 1.6E-49 T 13-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 THITH_12065 fee418a097c7ce0be07789d835d37d80 257 TIGRFAM TIGR00466 kdsB: 3-deoxy-D-manno-octulosonate cytidylyltransferase 6 245 1.7E-73 T 13-10-2018 IPR004528 3-deoxy-D-manno-octulosonate cytidylyltransferase GO:0005737|GO:0008690 KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269 THITH_12065 fee418a097c7ce0be07789d835d37d80 257 Gene3D G3DSA:3.90.550.10 7 255 1.9E-82 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_02985 d08af27215a943d9e4e4202bd47a7c37 117 Pfam PF05717 IS66 Orf2 like protein 9 106 7.1E-40 T 13-10-2018 IPR008878 Transposase IS66, Orf2 THITH_15450 d08af27215a943d9e4e4202bd47a7c37 117 Pfam PF05717 IS66 Orf2 like protein 9 106 7.1E-40 T 13-10-2018 IPR008878 Transposase IS66, Orf2 THITH_04610 d08af27215a943d9e4e4202bd47a7c37 117 Pfam PF05717 IS66 Orf2 like protein 9 106 7.1E-40 T 13-10-2018 IPR008878 Transposase IS66, Orf2 THITH_11200 d08af27215a943d9e4e4202bd47a7c37 117 Pfam PF05717 IS66 Orf2 like protein 9 106 7.1E-40 T 13-10-2018 IPR008878 Transposase IS66, Orf2 THITH_17085 6563ae47c7c0f8aa58cda6c2737bfb82 85 PRINTS PR00160 Glutaredoxin signature 55 68 4.3E-7 T 13-10-2018 IPR014025 Glutaredoxin subgroup THITH_17085 6563ae47c7c0f8aa58cda6c2737bfb82 85 PRINTS PR00160 Glutaredoxin signature 41 54 4.3E-7 T 13-10-2018 IPR014025 Glutaredoxin subgroup THITH_17085 6563ae47c7c0f8aa58cda6c2737bfb82 85 SUPERFAMILY SSF52833 1 81 8.99E-26 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_17085 6563ae47c7c0f8aa58cda6c2737bfb82 85 Gene3D G3DSA:3.40.30.10 1 84 5.3E-23 T 13-10-2018 THITH_17085 6563ae47c7c0f8aa58cda6c2737bfb82 85 ProSitePatterns PS00195 Glutaredoxin active site. 1 17 - T 13-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 THITH_17085 6563ae47c7c0f8aa58cda6c2737bfb82 85 TIGRFAM TIGR02181 GRX_bact: glutaredoxin 3 1 76 2.8E-29 T 13-10-2018 IPR011900 Glutaredoxin, GrxC GO:0045454 THITH_17085 6563ae47c7c0f8aa58cda6c2737bfb82 85 Pfam PF00462 Glutaredoxin 1 58 5.0E-17 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 THITH_09710 5f6008ec08732bec42145cb3d1aaaa6c 225 Gene3D G3DSA:3.40.50.850 6 223 1.6E-47 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 THITH_09710 5f6008ec08732bec42145cb3d1aaaa6c 225 Pfam PF00857 Isochorismatase family 28 215 4.9E-30 T 13-10-2018 IPR000868 Isochorismatase-like GO:0003824 THITH_09710 5f6008ec08732bec42145cb3d1aaaa6c 225 SUPERFAMILY SSF52499 9 221 1.83E-46 T 13-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 THITH_03915 45bad7105c4ab58cb6933bdec08b8857 265 PIRSF PIRSF012318 1 265 1.6E-96 T 13-10-2018 IPR011197 Uncharacterised conserved protein UCP012318 THITH_03915 45bad7105c4ab58cb6933bdec08b8857 265 Pfam PF04305 Protein of unknown function (DUF455) 12 256 1.9E-97 T 13-10-2018 IPR007402 Protein of unknown function DUF455 THITH_03915 45bad7105c4ab58cb6933bdec08b8857 265 SUPERFAMILY SSF47240 73 215 1.06E-16 T 13-10-2018 IPR009078 Ferritin-like superfamily THITH_06165 45bee12c74f1b78a0023a5e81416317d 181 Pfam PF13563 2'-5' RNA ligase superfamily 16 133 8.6E-11 T 13-10-2018 THITH_06165 45bee12c74f1b78a0023a5e81416317d 181 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 8 173 19.105 T 13-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 THITH_06165 45bee12c74f1b78a0023a5e81416317d 181 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 9 173 3.6E-30 T 13-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 THITH_06165 45bee12c74f1b78a0023a5e81416317d 181 SUPERFAMILY SSF55144 9 174 4.53E-38 T 13-10-2018 IPR009097 Cyclic phosphodiesterase THITH_06165 45bee12c74f1b78a0023a5e81416317d 181 Gene3D G3DSA:3.90.1140.10 4 174 2.0E-41 T 13-10-2018 THITH_07070 9be1a5406394b6d048d24c28d61514e7 468 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 30 208 2.6E-48 T 13-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THITH_07070 9be1a5406394b6d048d24c28d61514e7 468 SMART SM00977 370 439 2.6E-12 T 13-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THITH_07070 9be1a5406394b6d048d24c28d61514e7 468 Gene3D G3DSA:3.40.50.620 23 236 7.9E-61 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_07070 9be1a5406394b6d048d24c28d61514e7 468 SUPERFAMILY SSF52402 25 214 1.57E-48 T 13-10-2018 THITH_07070 9be1a5406394b6d048d24c28d61514e7 468 Pfam PF11734 TilS substrate C-terminal domain 370 419 1.2E-14 T 13-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THITH_07070 9be1a5406394b6d048d24c28d61514e7 468 Gene3D G3DSA:1.20.59.20 243 323 1.2E-11 T 13-10-2018 THITH_07070 9be1a5406394b6d048d24c28d61514e7 468 SUPERFAMILY SSF56037 337 420 7.32E-16 T 13-10-2018 THITH_07070 9be1a5406394b6d048d24c28d61514e7 468 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 16 312 21.6 T 13-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THITH_07070 9be1a5406394b6d048d24c28d61514e7 468 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 371 411 3.1E-10 T 13-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THITH_07070 9be1a5406394b6d048d24c28d61514e7 468 SUPERFAMILY SSF82829 250 323 1.12E-14 T 13-10-2018 THITH_07070 9be1a5406394b6d048d24c28d61514e7 468 Pfam PF01171 PP-loop family 30 204 2.4E-51 T 13-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 THITH_07070 9be1a5406394b6d048d24c28d61514e7 468 Pfam PF09179 TilS substrate binding domain 253 320 7.0E-13 T 13-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 THITH_14035 0c5366b212b5ff662f3173063dd8ca2a 128 Gene3D G3DSA:3.30.460.10 1 116 2.2E-39 T 13-10-2018 THITH_14035 0c5366b212b5ff662f3173063dd8ca2a 128 SUPERFAMILY SSF81301 1 105 1.8E-39 T 13-10-2018 THITH_14035 0c5366b212b5ff662f3173063dd8ca2a 128 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 7 104 7.8E-39 T 13-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS THITH_14035 0c5366b212b5ff662f3173063dd8ca2a 128 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 4.8E-28 T 13-10-2018 THITH_14035 0c5366b212b5ff662f3173063dd8ca2a 128 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 3 105 25.078 T 13-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS THITH_10695 4bb0f2e86bee2ec13756a0936521c402 257 Gene3D G3DSA:3.40.50.300 6 257 9.7E-61 T 13-10-2018 THITH_10695 4bb0f2e86bee2ec13756a0936521c402 257 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_10695 4bb0f2e86bee2ec13756a0936521c402 257 Pfam PF00005 ABC transporter 25 173 1.0E-28 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_10695 4bb0f2e86bee2ec13756a0936521c402 257 SUPERFAMILY SSF52540 4 248 1.17E-60 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_10695 4bb0f2e86bee2ec13756a0936521c402 257 SMART SM00382 33 222 2.3E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_11135 eac504f3a35564d0298f66c040d021f5 59 Gene3D G3DSA:1.10.260.40 1 59 5.2E-23 T 13-10-2018 THITH_11135 eac504f3a35564d0298f66c040d021f5 59 SUPERFAMILY SSF47413 2 46 5.63E-12 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 THITH_11135 eac504f3a35564d0298f66c040d021f5 59 Pfam PF13560 Helix-turn-helix domain 1 57 3.2E-10 T 13-10-2018 THITH_11135 eac504f3a35564d0298f66c040d021f5 59 SMART SM00530 1 54 2.5E-6 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_14990 31529f5f23d2f0fa04e9c6306ff52e5e 201 PIRSF PIRSF015617 5 201 8.7E-66 T 13-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 THITH_14990 31529f5f23d2f0fa04e9c6306ff52e5e 201 Pfam PF12557 Cob(I)alamin adenosyltransferase N terminal 1 25 1.5E-6 T 13-10-2018 IPR025826 Cob(I)alamin adenosyltransferase N-terminal domain KEGG: 00860+2.5.1.17 THITH_14990 31529f5f23d2f0fa04e9c6306ff52e5e 201 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 29 200 8.7E-64 T 13-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 THITH_14990 31529f5f23d2f0fa04e9c6306ff52e5e 201 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 32 200 3.4E-57 T 13-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 THITH_14990 31529f5f23d2f0fa04e9c6306ff52e5e 201 SUPERFAMILY SSF52540 11 200 4.3E-68 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14990 31529f5f23d2f0fa04e9c6306ff52e5e 201 Gene3D G3DSA:3.40.50.300 10 201 1.0E-64 T 13-10-2018 THITH_09215 52e647eb7564ab950875973858259883 410 TIGRFAM TIGR02678 TIGR02678: TIGR02678 family protein 16 392 6.0E-99 T 13-10-2018 IPR013494 Conserved hypothetical protein CHP02678 THITH_09215 52e647eb7564ab950875973858259883 410 Pfam PF09661 Protein of unknown function (DUF2398) 17 392 2.4E-109 T 13-10-2018 IPR013494 Conserved hypothetical protein CHP02678 THITH_09285 a53792bfdd895afd5b30029fc57a24c3 293 TIGRFAM TIGR02580 cas_RAMP_Cmr4: CRISPR type III-B/RAMP module RAMP protein Cmr4 5 285 1.2E-57 T 13-10-2018 IPR013410 CRISPR-associated RAMP Cmr4 THITH_09285 a53792bfdd895afd5b30029fc57a24c3 293 Pfam PF03787 RAMP superfamily 8 285 1.0E-19 T 13-10-2018 IPR005537 CRISPR type III-associated RAMP protein THITH_01660 b7423d404695a3f76a7d9fb755e5bc41 327 TIGRFAM TIGR02570 cas7_GSU0053: CRISPR-associated protein GSU0053/csb1, Dpsyc system 1 166 9.0E-31 T 13-10-2018 IPR013403 CRISPR-associated protein GSU0053 THITH_01660 b7423d404695a3f76a7d9fb755e5bc41 327 Pfam PF09617 CRISPR-associated protein GSU0053 (Cas_GSU0053) 3 160 1.5E-31 T 13-10-2018 IPR013403 CRISPR-associated protein GSU0053 THITH_13690 a74cecd2b9d680e773e68e0a46a270df 212 Gene3D G3DSA:3.40.50.1360 1 208 8.3E-71 T 13-10-2018 THITH_13690 a74cecd2b9d680e773e68e0a46a270df 212 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 1 196 3.8E-61 T 13-10-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 THITH_13690 a74cecd2b9d680e773e68e0a46a270df 212 SUPERFAMILY SSF100950 1 206 1.73E-59 T 13-10-2018 IPR037171 NagB/RpiA transferase-like THITH_13690 a74cecd2b9d680e773e68e0a46a270df 212 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 2 204 5.7E-54 T 13-10-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 THITH_03275 10637d1ebd85b584c20e42b424e6bd21 132 Pfam PF02472 Biopolymer transport protein ExbD/TolR 12 129 1.1E-21 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 THITH_03275 10637d1ebd85b584c20e42b424e6bd21 132 Gene3D G3DSA:3.30.420.270 56 126 1.9E-7 T 13-10-2018 THITH_04630 f4f4386fd2ce733eff0fd911c38133ca 244 Pfam PF00589 Phage integrase family 111 208 8.8E-12 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THITH_04630 f4f4386fd2ce733eff0fd911c38133ca 244 Pfam PF13495 Phage integrase, N-terminal SAM-like domain 14 91 3.1E-16 T 13-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 THITH_04630 f4f4386fd2ce733eff0fd911c38133ca 244 Gene3D G3DSA:1.10.150.130 11 94 3.0E-11 T 13-10-2018 IPR010998 Integrase/recombinase, N-terminal THITH_04630 f4f4386fd2ce733eff0fd911c38133ca 244 SUPERFAMILY SSF56349 9 218 6.47E-29 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THITH_04630 f4f4386fd2ce733eff0fd911c38133ca 244 Gene3D G3DSA:1.10.443.10 101 238 1.4E-20 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 THITH_04105 a0abb5aa730ff1730b38cc6eb89b50d2 207 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 85 101 - T 13-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 THITH_04105 a0abb5aa730ff1730b38cc6eb89b50d2 207 Gene3D G3DSA:1.10.286.10 23 75 2.1E-21 T 13-10-2018 THITH_04105 a0abb5aa730ff1730b38cc6eb89b50d2 207 SUPERFAMILY SSF55620 24 206 9.64E-80 T 13-10-2018 THITH_04105 a0abb5aa730ff1730b38cc6eb89b50d2 207 Gene3D G3DSA:3.30.1130.10 76 207 3.5E-61 T 13-10-2018 THITH_04105 a0abb5aa730ff1730b38cc6eb89b50d2 207 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 133 143 - T 13-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 THITH_04105 a0abb5aa730ff1730b38cc6eb89b50d2 207 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 24 206 39.203 T 13-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 THITH_04105 a0abb5aa730ff1730b38cc6eb89b50d2 207 Pfam PF01227 GTP cyclohydrolase I 29 205 3.5E-76 T 13-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 THITH_04105 a0abb5aa730ff1730b38cc6eb89b50d2 207 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 29 207 1.4E-76 T 13-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 THITH_13955 cc7a8cf25c1b951b14650e688c2b0531 557 SUPERFAMILY SSF52540 337 543 3.62E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13955 cc7a8cf25c1b951b14650e688c2b0531 557 Gene3D G3DSA:3.40.50.300 340 547 5.1E-51 T 13-10-2018 THITH_13955 cc7a8cf25c1b951b14650e688c2b0531 557 SMART SM00382 370 556 2.8E-7 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_13955 cc7a8cf25c1b951b14650e688c2b0531 557 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 14 539 1.2E-102 T 13-10-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0016021|GO:0034775|GO:0042626|GO:0045454 THITH_13955 cc7a8cf25c1b951b14650e688c2b0531 557 Pfam PF00005 ABC transporter 363 510 7.3E-23 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_13955 cc7a8cf25c1b951b14650e688c2b0531 557 ProSitePatterns PS00211 ABC transporters family signature. 482 496 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_13955 cc7a8cf25c1b951b14650e688c2b0531 557 SUPERFAMILY SSF90123 8 318 2.09E-33 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THITH_13955 cc7a8cf25c1b951b14650e688c2b0531 557 Gene3D G3DSA:1.20.1560.10 7 318 9.4E-22 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THITH_05540 8b2d9fb5dd4227f3ac274e0ec6e68ed0 771 Gene3D G3DSA:1.10.287.110 79 134 2.7E-5 T 13-10-2018 IPR036869 Chaperone J-domain superfamily THITH_05540 8b2d9fb5dd4227f3ac274e0ec6e68ed0 771 SUPERFAMILY SSF54427 656 770 7.13E-8 T 13-10-2018 IPR032710 NTF2-like domain superfamily THITH_05540 8b2d9fb5dd4227f3ac274e0ec6e68ed0 771 Gene3D G3DSA:3.10.450.50 645 771 4.9E-6 T 13-10-2018 THITH_00075 e82e52149a49dcba6684524fcae6f615 476 Hamap MF_00006 Argininosuccinate lyase [argH]. 16 467 43.923 T 13-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THITH_00075 e82e52149a49dcba6684524fcae6f615 476 Gene3D G3DSA:1.10.275.10 39 243 3.5E-189 T 13-10-2018 IPR024083 Fumarase/histidase, N-terminal THITH_00075 e82e52149a49dcba6684524fcae6f615 476 Gene3D G3DSA:1.10.40.30 374 446 3.5E-189 T 13-10-2018 THITH_00075 e82e52149a49dcba6684524fcae6f615 476 Pfam PF14698 Argininosuccinate lyase C-terminal 377 443 4.0E-23 T 13-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THITH_00075 e82e52149a49dcba6684524fcae6f615 476 SUPERFAMILY SSF48557 17 469 1.41E-154 T 13-10-2018 IPR008948 L-Aspartase-like GO:0003824 THITH_00075 e82e52149a49dcba6684524fcae6f615 476 TIGRFAM TIGR00838 argH: argininosuccinate lyase 17 469 2.5E-190 T 13-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 THITH_00075 e82e52149a49dcba6684524fcae6f615 476 PRINTS PR00145 Argininosuccinate lyase family signature 207 223 7.4E-68 T 13-10-2018 THITH_00075 e82e52149a49dcba6684524fcae6f615 476 PRINTS PR00145 Argininosuccinate lyase family signature 245 269 7.4E-68 T 13-10-2018 THITH_00075 e82e52149a49dcba6684524fcae6f615 476 PRINTS PR00145 Argininosuccinate lyase family signature 324 343 7.4E-68 T 13-10-2018 THITH_00075 e82e52149a49dcba6684524fcae6f615 476 PRINTS PR00145 Argininosuccinate lyase family signature 115 137 7.4E-68 T 13-10-2018 THITH_00075 e82e52149a49dcba6684524fcae6f615 476 PRINTS PR00145 Argininosuccinate lyase family signature 156 176 7.4E-68 T 13-10-2018 THITH_00075 e82e52149a49dcba6684524fcae6f615 476 PRINTS PR00145 Argininosuccinate lyase family signature 289 305 7.4E-68 T 13-10-2018 THITH_00075 e82e52149a49dcba6684524fcae6f615 476 Pfam PF00206 Lyase 20 314 2.5E-82 T 13-10-2018 IPR022761 Fumarate lyase, N-terminal THITH_00075 e82e52149a49dcba6684524fcae6f615 476 PRINTS PR00149 Fumarate lyase superfamily signature 161 179 6.3E-30 T 13-10-2018 IPR000362 Fumarate lyase family THITH_00075 e82e52149a49dcba6684524fcae6f615 476 PRINTS PR00149 Fumarate lyase superfamily signature 116 134 6.3E-30 T 13-10-2018 IPR000362 Fumarate lyase family THITH_00075 e82e52149a49dcba6684524fcae6f615 476 PRINTS PR00149 Fumarate lyase superfamily signature 245 272 6.3E-30 T 13-10-2018 IPR000362 Fumarate lyase family THITH_00075 e82e52149a49dcba6684524fcae6f615 476 PRINTS PR00149 Fumarate lyase superfamily signature 289 305 6.3E-30 T 13-10-2018 IPR000362 Fumarate lyase family THITH_00075 e82e52149a49dcba6684524fcae6f615 476 Gene3D G3DSA:1.20.200.10 133 462 3.5E-189 T 13-10-2018 THITH_00075 e82e52149a49dcba6684524fcae6f615 476 ProSitePatterns PS00163 Fumarate lyases signature. 289 298 - T 13-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 THITH_09695 3c2cbdd300381feb65eaaa8006c8baa2 385 SUPERFAMILY SSF159501 29 288 2.09E-65 T 13-10-2018 THITH_09695 3c2cbdd300381feb65eaaa8006c8baa2 385 SMART SM00228 301 371 1.3E-7 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_09695 3c2cbdd300381feb65eaaa8006c8baa2 385 Gene3D G3DSA:3.40.50.11550 43 257 3.9E-25 T 13-10-2018 THITH_09695 3c2cbdd300381feb65eaaa8006c8baa2 385 Pfam PF04187 Haem-binding uptake, Tiki superfamily, ChaN 48 253 3.0E-63 T 13-10-2018 IPR007314 Haem-binding uptake, Tiki superfamily, ChaN THITH_09695 3c2cbdd300381feb65eaaa8006c8baa2 385 Gene3D G3DSA:1.10.8.760 153 218 3.9E-25 T 13-10-2018 THITH_09695 3c2cbdd300381feb65eaaa8006c8baa2 385 Pfam PF13180 PDZ domain 303 376 1.0E-8 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_09695 3c2cbdd300381feb65eaaa8006c8baa2 385 SUPERFAMILY SSF50156 306 377 2.37E-14 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 THITH_09695 3c2cbdd300381feb65eaaa8006c8baa2 385 Gene3D G3DSA:2.30.42.10 302 385 3.9E-16 T 13-10-2018 THITH_03975 0131bdf1966e0d4c6af9846db65d7c1e 89 Gene3D G3DSA:1.10.760.10 1 89 5.5E-34 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_03975 0131bdf1966e0d4c6af9846db65d7c1e 89 SUPERFAMILY SSF46626 5 89 2.27E-24 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_11430 364753442761a93449101f5fcf57c250 188 Gene3D G3DSA:1.20.120.740 4 183 6.6E-46 T 13-10-2018 THITH_11430 364753442761a93449101f5fcf57c250 188 SUPERFAMILY SSF101327 8 176 4.18E-27 T 13-10-2018 IPR036255 YgfB-like superfamily THITH_11430 364753442761a93449101f5fcf57c250 188 Pfam PF03695 Uncharacterised protein family (UPF0149) 12 177 5.2E-27 T 13-10-2018 IPR011978 Uncharacterised protein family UPF0149 THITH_05045 61d91823fc61d4c7fcb038e9139e8489 365 TIGRFAM TIGR01209 TIGR01209: RNA ligase, Pab1020 family 16 365 3.5E-86 T 13-10-2018 IPR001072 RNA ligase, Pab1020 family THITH_05045 61d91823fc61d4c7fcb038e9139e8489 365 SUPERFAMILY SSF56091 48 219 4.11E-30 T 13-10-2018 THITH_05045 61d91823fc61d4c7fcb038e9139e8489 365 Gene3D G3DSA:3.30.1490.70 56 226 6.5E-60 T 13-10-2018 THITH_05045 61d91823fc61d4c7fcb038e9139e8489 365 PRINTS PR01048 Hypothetical protein Y414 family signature 93 108 4.0E-41 T 13-10-2018 IPR001072 RNA ligase, Pab1020 family THITH_05045 61d91823fc61d4c7fcb038e9139e8489 365 PRINTS PR01048 Hypothetical protein Y414 family signature 149 170 4.0E-41 T 13-10-2018 IPR001072 RNA ligase, Pab1020 family THITH_05045 61d91823fc61d4c7fcb038e9139e8489 365 PRINTS PR01048 Hypothetical protein Y414 family signature 274 288 4.0E-41 T 13-10-2018 IPR001072 RNA ligase, Pab1020 family THITH_05045 61d91823fc61d4c7fcb038e9139e8489 365 PRINTS PR01048 Hypothetical protein Y414 family signature 72 85 4.0E-41 T 13-10-2018 IPR001072 RNA ligase, Pab1020 family THITH_05045 61d91823fc61d4c7fcb038e9139e8489 365 PRINTS PR01048 Hypothetical protein Y414 family signature 204 217 4.0E-41 T 13-10-2018 IPR001072 RNA ligase, Pab1020 family THITH_05045 61d91823fc61d4c7fcb038e9139e8489 365 PRINTS PR01048 Hypothetical protein Y414 family signature 340 360 4.0E-41 T 13-10-2018 IPR001072 RNA ligase, Pab1020 family THITH_05045 61d91823fc61d4c7fcb038e9139e8489 365 PRINTS PR01048 Hypothetical protein Y414 family signature 28 42 4.0E-41 T 13-10-2018 IPR001072 RNA ligase, Pab1020 family THITH_05045 61d91823fc61d4c7fcb038e9139e8489 365 PRINTS PR01048 Hypothetical protein Y414 family signature 245 263 4.0E-41 T 13-10-2018 IPR001072 RNA ligase, Pab1020 family THITH_05045 61d91823fc61d4c7fcb038e9139e8489 365 PRINTS PR01048 Hypothetical protein Y414 family signature 123 138 4.0E-41 T 13-10-2018 IPR001072 RNA ligase, Pab1020 family THITH_05045 61d91823fc61d4c7fcb038e9139e8489 365 PRINTS PR01048 Hypothetical protein Y414 family signature 50 68 4.0E-41 T 13-10-2018 IPR001072 RNA ligase, Pab1020 family THITH_05045 61d91823fc61d4c7fcb038e9139e8489 365 Gene3D G3DSA:3.30.470.30 81 182 6.5E-60 T 13-10-2018 THITH_05045 61d91823fc61d4c7fcb038e9139e8489 365 Gene3D G3DSA:3.30.70.2160 227 365 2.7E-44 T 13-10-2018 THITH_05045 61d91823fc61d4c7fcb038e9139e8489 365 Pfam PF09414 RNA ligase 71 224 1.0E-10 T 13-10-2018 IPR021122 RNA ligase domain, REL/Rln2 THITH_00755 3e1bc04ed742ec0c93110b2f9e18d9ca 204 Gene3D G3DSA:3.40.50.150 47 204 8.4E-44 T 13-10-2018 THITH_00755 3e1bc04ed742ec0c93110b2f9e18d9ca 204 Pfam PF13847 Methyltransferase domain 79 198 1.6E-27 T 13-10-2018 IPR025714 Methyltransferase domain THITH_00755 3e1bc04ed742ec0c93110b2f9e18d9ca 204 SUPERFAMILY SSF53335 75 192 2.05E-33 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_00555 294258b7ecabfbce680f5137b956ec3e 491 Gene3D G3DSA:3.40.50.300 241 491 9.6E-102 T 13-10-2018 THITH_00555 294258b7ecabfbce680f5137b956ec3e 491 Gene3D G3DSA:3.40.50.300 1 236 1.0E-69 T 13-10-2018 THITH_00555 294258b7ecabfbce680f5137b956ec3e 491 SUPERFAMILY SSF52540 299 479 2.92E-24 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00555 294258b7ecabfbce680f5137b956ec3e 491 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 11 231 2.6E-49 T 13-10-2018 IPR022488 Polyphosphate kinase-2-related THITH_00555 294258b7ecabfbce680f5137b956ec3e 491 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 268 489 1.6E-83 T 13-10-2018 IPR022488 Polyphosphate kinase-2-related THITH_00555 294258b7ecabfbce680f5137b956ec3e 491 TIGRFAM TIGR03708 poly_P_AMP_trns: polyphosphate:AMP phosphotransferase 2 491 1.5E-211 T 13-10-2018 IPR022489 Polyphosphate:AMP phosphotransferase GO:0006797|GO:0043751 THITH_00555 294258b7ecabfbce680f5137b956ec3e 491 SUPERFAMILY SSF52540 40 216 1.14E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_10100 c71fdecdc36ce7ae5f1597bd031a0694 267 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 60 235 1.0E-31 T 13-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 THITH_10100 c71fdecdc36ce7ae5f1597bd031a0694 267 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 61 233 1.9E-45 T 13-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 THITH_07980 91ba6e22d3544c1777696057e43c5e47 402 Gene3D G3DSA:1.25.40.10 21 319 1.9E-26 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_07980 91ba6e22d3544c1777696057e43c5e47 402 SUPERFAMILY SSF48452 40 316 1.61E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_07980 91ba6e22d3544c1777696057e43c5e47 402 SMART SM00028 35 68 260.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_07980 91ba6e22d3544c1777696057e43c5e47 402 SMART SM00028 69 101 430.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_07980 91ba6e22d3544c1777696057e43c5e47 402 SMART SM00028 214 247 46.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_07980 91ba6e22d3544c1777696057e43c5e47 402 SMART SM00028 180 213 23.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_07980 91ba6e22d3544c1777696057e43c5e47 402 SMART SM00028 285 318 200.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_07980 91ba6e22d3544c1777696057e43c5e47 402 Hamap MF_00994 Lipopolysaccharide assembly protein B [lapB]. 5 391 30.018 T 13-10-2018 IPR030865 Lipopolysaccharide assembly protein B GO:0008653 THITH_07980 91ba6e22d3544c1777696057e43c5e47 402 Pfam PF13432 Tetratricopeptide repeat 185 245 5.0E-7 T 13-10-2018 THITH_02255 2e055b44aa57376642b8245cd30ff190 80 SUPERFAMILY SSF143120 5 48 4.71E-9 T 13-10-2018 IPR036165 YefM-like superfamily THITH_02255 2e055b44aa57376642b8245cd30ff190 80 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 44 2.9E-9 T 13-10-2018 THITH_02255 2e055b44aa57376642b8245cd30ff190 80 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 48 1.5E-10 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THITH_02255 2e055b44aa57376642b8245cd30ff190 80 Gene3D G3DSA:3.40.1620.10 3 40 2.8E-8 T 13-10-2018 THITH_01625 0c4994057e68d92cce632f8d835a271c 59 Pfam PF02599 Global regulator protein family 1 50 2.7E-23 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 THITH_01625 0c4994057e68d92cce632f8d835a271c 59 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 47 1.0E-13 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 THITH_01625 0c4994057e68d92cce632f8d835a271c 59 Hamap MF_00167 Translational regulator CsrA [csrA]. 1 58 17.025 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 THITH_01625 0c4994057e68d92cce632f8d835a271c 59 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 49 6.4E-22 T 13-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 THITH_01625 0c4994057e68d92cce632f8d835a271c 59 SUPERFAMILY SSF117130 1 50 4.58E-18 T 13-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 THITH_01625 0c4994057e68d92cce632f8d835a271c 59 Gene3D G3DSA:3.30.70.1680 1 57 1.8E-23 T 13-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 THITH_02625 b40cf905d6066b347e9065e3d9d0270c 288 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 207 219 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site THITH_02625 b40cf905d6066b347e9065e3d9d0270c 288 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 75 91 - T 13-10-2018 IPR033749 Polyprenyl synthetase, conserved site THITH_02625 b40cf905d6066b347e9065e3d9d0270c 288 SUPERFAMILY SSF48576 3 281 4.32E-84 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily THITH_02625 b40cf905d6066b347e9065e3d9d0270c 288 Pfam PF00348 Polyprenyl synthetase 25 264 1.4E-56 T 13-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 THITH_02625 b40cf905d6066b347e9065e3d9d0270c 288 Gene3D G3DSA:1.10.600.10 1 288 1.1E-97 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily THITH_10120 d2f1f4db2401e78ecd072e88b77ddbf0 633 Gene3D G3DSA:3.40.50.720 280 604 2.7E-114 T 13-10-2018 THITH_10120 d2f1f4db2401e78ecd072e88b77ddbf0 633 SUPERFAMILY SSF51735 282 546 5.2E-60 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_10120 d2f1f4db2401e78ecd072e88b77ddbf0 633 Pfam PF13727 CoA-binding domain 66 234 1.7E-13 T 13-10-2018 THITH_10120 d2f1f4db2401e78ecd072e88b77ddbf0 633 Pfam PF02719 Polysaccharide biosynthesis protein 285 567 9.3E-119 T 13-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain THITH_10120 d2f1f4db2401e78ecd072e88b77ddbf0 633 SUPERFAMILY SSF51735 145 271 1.97E-21 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_10120 d2f1f4db2401e78ecd072e88b77ddbf0 633 Gene3D G3DSA:3.40.50.720 143 266 2.2E-34 T 13-10-2018 THITH_01735 1b6d643483430ead20d0d4e8ecb20f3b 984 Gene3D G3DSA:3.30.70.270 527 693 3.5E-52 T 13-10-2018 THITH_01735 1b6d643483430ead20d0d4e8ecb20f3b 984 Pfam PF08448 PAS fold 429 525 9.7E-7 T 13-10-2018 IPR013656 PAS fold-4 THITH_01735 1b6d643483430ead20d0d4e8ecb20f3b 984 Pfam PF00990 Diguanylate cyclase, GGDEF domain 535 686 1.2E-43 T 13-10-2018 IPR000160 GGDEF domain THITH_01735 1b6d643483430ead20d0d4e8ecb20f3b 984 SMART SM00091 418 484 3.8E-4 T 13-10-2018 IPR000014 PAS domain THITH_01735 1b6d643483430ead20d0d4e8ecb20f3b 984 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 420 531 9.7E-8 T 13-10-2018 IPR000014 PAS domain THITH_01735 1b6d643483430ead20d0d4e8ecb20f3b 984 SUPERFAMILY SSF55785 431 531 4.19E-11 T 13-10-2018 IPR035965 PAS domain superfamily THITH_01735 1b6d643483430ead20d0d4e8ecb20f3b 984 Pfam PF14827 Double sensory domain of two-component sensor kinase 77 308 5.3E-26 T 13-10-2018 IPR029150 Double Cache domain 3 THITH_01735 1b6d643483430ead20d0d4e8ecb20f3b 984 Gene3D G3DSA:3.20.20.450 694 952 1.3E-84 T 13-10-2018 IPR035919 EAL domain superfamily THITH_01735 1b6d643483430ead20d0d4e8ecb20f3b 984 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 531 688 8.5E-37 T 13-10-2018 IPR000160 GGDEF domain THITH_01735 1b6d643483430ead20d0d4e8ecb20f3b 984 Gene3D G3DSA:3.30.450.20 407 526 4.0E-12 T 13-10-2018 THITH_01735 1b6d643483430ead20d0d4e8ecb20f3b 984 SUPERFAMILY SSF55073 540 692 1.92E-43 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_01735 1b6d643483430ead20d0d4e8ecb20f3b 984 Pfam PF00563 EAL domain 713 945 3.0E-64 T 13-10-2018 IPR001633 EAL domain THITH_01735 1b6d643483430ead20d0d4e8ecb20f3b 984 SMART SM00052 705 950 1.8E-84 T 13-10-2018 IPR001633 EAL domain THITH_01735 1b6d643483430ead20d0d4e8ecb20f3b 984 SMART SM00267 524 693 1.0E-53 T 13-10-2018 IPR000160 GGDEF domain THITH_01735 1b6d643483430ead20d0d4e8ecb20f3b 984 SUPERFAMILY SSF141868 711 952 7.06E-78 T 13-10-2018 IPR035919 EAL domain superfamily THITH_08830 a3c7a1ec0625c865421503c08da222a6 133 Pfam PF01850 PIN domain 4 123 1.3E-13 T 13-10-2018 IPR002716 PIN domain THITH_08830 a3c7a1ec0625c865421503c08da222a6 133 SUPERFAMILY SSF88723 1 131 1.12E-33 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_08830 a3c7a1ec0625c865421503c08da222a6 133 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 4 130 12.32 T 13-10-2018 IPR022907 VapC family GO:0004540 THITH_08830 a3c7a1ec0625c865421503c08da222a6 133 Gene3D G3DSA:3.40.50.1010 1 132 3.1E-40 T 13-10-2018 THITH_13975 3c6c522c1f80fbfe0d2b478b071b0408 244 SUPERFAMILY SSF64438 3 242 1.58E-82 T 13-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic THITH_13975 3c6c522c1f80fbfe0d2b478b071b0408 244 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 29 242 9.8E-58 T 13-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase THITH_13975 3c6c522c1f80fbfe0d2b478b071b0408 244 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 19 241 1.3E-78 T 13-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase THITH_13975 3c6c522c1f80fbfe0d2b478b071b0408 244 Gene3D G3DSA:3.60.140.10 1 243 8.6E-92 T 13-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily THITH_05760 7598e42bdf4580312b61f70a3cdbc26f 197 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 51 75 4.3E-5 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_05760 7598e42bdf4580312b61f70a3cdbc26f 197 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 102 136 4.7E-6 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_05760 7598e42bdf4580312b61f70a3cdbc26f 197 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 14 49 1.9E-6 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_05760 7598e42bdf4580312b61f70a3cdbc26f 197 SUPERFAMILY SSF51161 4 157 2.09E-43 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily THITH_05760 7598e42bdf4580312b61f70a3cdbc26f 197 Gene3D G3DSA:2.20.70.110 153 190 4.9E-13 T 13-10-2018 THITH_05760 7598e42bdf4580312b61f70a3cdbc26f 197 Gene3D G3DSA:2.160.10.10 1 151 1.5E-47 T 13-10-2018 THITH_09240 fd57a6aa10016cabb678c4dbc819741d 246 Gene3D G3DSA:3.100.10.20 3 75 1.3E-5 T 13-10-2018 THITH_09240 fd57a6aa10016cabb678c4dbc819741d 246 Pfam PF01867 CRISPR associated protein Cas1 5 80 8.3E-6 T 13-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THITH_10750 72d5901c142055e4c3ea2e4780cee344 319 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 1 284 6.9E-130 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THITH_10750 72d5901c142055e4c3ea2e4780cee344 319 Gene3D G3DSA:3.90.226.10 26 287 8.1E-85 T 13-10-2018 THITH_10750 72d5901c142055e4c3ea2e4780cee344 319 SUPERFAMILY SSF52096 26 281 4.42E-86 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THITH_10750 72d5901c142055e4c3ea2e4780cee344 319 Pfam PF01039 Carboxyl transferase domain 98 240 1.2E-13 T 13-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 THITH_10750 72d5901c142055e4c3ea2e4780cee344 319 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 1 282 38.447 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THITH_10750 72d5901c142055e4c3ea2e4780cee344 319 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 130 144 2.0E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THITH_10750 72d5901c142055e4c3ea2e4780cee344 319 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 164 182 2.0E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THITH_10750 72d5901c142055e4c3ea2e4780cee344 319 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 230 241 2.0E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THITH_10750 72d5901c142055e4c3ea2e4780cee344 319 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 201 218 2.0E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THITH_10750 72d5901c142055e4c3ea2e4780cee344 319 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 252 261 2.0E-37 T 13-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THITH_04520 be526e459787d518b9cb6b242c4b8238 296 Gene3D G3DSA:3.90.1170.20 27 294 2.2E-104 T 13-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 THITH_04520 be526e459787d518b9cb6b242c4b8238 296 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 131 294 1.6E-54 T 13-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 THITH_04520 be526e459787d518b9cb6b242c4b8238 296 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 32 294 3.3E-94 T 13-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 THITH_04520 be526e459787d518b9cb6b242c4b8238 296 Gene3D G3DSA:3.20.20.70 139 285 2.2E-104 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_04520 be526e459787d518b9cb6b242c4b8238 296 PIRSF PIRSF006250 25 296 2.4E-92 T 13-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 THITH_04520 be526e459787d518b9cb6b242c4b8238 296 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 41 128 1.2E-24 T 13-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 THITH_04520 be526e459787d518b9cb6b242c4b8238 296 SUPERFAMILY SSF54675 27 129 1.18E-28 T 13-10-2018 THITH_04520 be526e459787d518b9cb6b242c4b8238 296 SUPERFAMILY SSF51690 131 294 1.57E-56 T 13-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 THITH_02160 3da818690fbe5f9ae348c7b62332917e 126 SUPERFAMILY SSF81301 6 96 1.85E-9 T 13-10-2018 THITH_02160 3da818690fbe5f9ae348c7b62332917e 126 Gene3D G3DSA:3.30.460.10 1 102 3.7E-10 T 13-10-2018 THITH_10765 f7f50329bdf18ea807b87f8f40fa613e 214 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 3 205 37.799 T 13-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 THITH_10765 f7f50329bdf18ea807b87f8f40fa613e 214 SUPERFAMILY SSF51366 3 203 4.39E-56 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 THITH_10765 f7f50329bdf18ea807b87f8f40fa613e 214 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 200 2.3E-41 T 13-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 THITH_10765 f7f50329bdf18ea807b87f8f40fa613e 214 Gene3D G3DSA:3.20.20.70 3 209 1.1E-62 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_01490 c6c17ce2635c2942d3135d0748ade187 145 SUPERFAMILY SSF54690 8 141 5.1E-41 T 13-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 THITH_01490 c6c17ce2635c2942d3135d0748ade187 145 Gene3D G3DSA:3.90.1170.40 1 144 2.8E-42 T 13-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 THITH_01490 c6c17ce2635c2942d3135d0748ade187 145 Pfam PF02391 MoaE protein 8 121 3.1E-30 T 13-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 THITH_15780 cdfcc6ea976a503e1080f0c55e4650f5 478 PIRSF PIRSF012666 1 478 1.0E-131 T 13-10-2018 IPR016602 Uncharacterised conserved protein UCP012666 THITH_15780 cdfcc6ea976a503e1080f0c55e4650f5 478 Gene3D G3DSA:3.30.590.20 41 468 6.6E-53 T 13-10-2018 THITH_15780 cdfcc6ea976a503e1080f0c55e4650f5 478 SUPERFAMILY SSF55931 42 464 5.3E-39 T 13-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 THITH_12090 2d59f4d57e37dd739678f863235eb074 141 Pfam PF02472 Biopolymer transport protein ExbD/TolR 7 133 4.0E-29 T 13-10-2018 IPR003400 Biopolymer transport protein ExbD/TolR GO:0022857|GO:0055085 THITH_12090 2d59f4d57e37dd739678f863235eb074 141 Gene3D G3DSA:3.30.420.270 60 131 4.4E-6 T 13-10-2018 THITH_15535 0295834cfa072ba827c56c2713626de2 215 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 49 202 5.1E-64 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 THITH_15535 0295834cfa072ba827c56c2713626de2 215 Pfam PF01625 Peptide methionine sulfoxide reductase 50 202 1.9E-65 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 THITH_15535 0295834cfa072ba827c56c2713626de2 215 SUPERFAMILY SSF55068 10 208 5.23E-77 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 THITH_15535 0295834cfa072ba827c56c2713626de2 215 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 47 208 37.205 T 13-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 THITH_15535 0295834cfa072ba827c56c2713626de2 215 Gene3D G3DSA:3.30.1060.10 7 215 1.7E-85 T 13-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 THITH_07065 53b88851dc34df353974ec942cd92111 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 88 99 3.2E-49 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THITH_07065 53b88851dc34df353974ec942cd92111 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 113 131 3.2E-49 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THITH_07065 53b88851dc34df353974ec942cd92111 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 153 166 3.2E-49 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THITH_07065 53b88851dc34df353974ec942cd92111 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 169 182 3.2E-49 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THITH_07065 53b88851dc34df353974ec942cd92111 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 197 206 3.2E-49 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THITH_07065 53b88851dc34df353974ec942cd92111 321 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 134 150 3.2E-49 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THITH_07065 53b88851dc34df353974ec942cd92111 321 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 5 316 51.082 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THITH_07065 53b88851dc34df353974ec942cd92111 321 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 148 1.6E-63 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THITH_07065 53b88851dc34df353974ec942cd92111 321 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 4 318 3.2E-153 T 13-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 THITH_07065 53b88851dc34df353974ec942cd92111 321 Gene3D G3DSA:3.90.226.10 1 318 6.3E-119 T 13-10-2018 THITH_07065 53b88851dc34df353974ec942cd92111 321 SUPERFAMILY SSF52096 6 316 2.13E-102 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THITH_07055 31c1f3a09abac97881596be218947b8f 206 SUPERFAMILY SSF53098 13 198 2.28E-64 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_07055 31c1f3a09abac97881596be218947b8f 206 Hamap MF_00052_B Ribonuclease HII [rnhB]. 14 193 36.287 T 13-10-2018 IPR022898 Ribonuclease HII GO:0004523 THITH_07055 31c1f3a09abac97881596be218947b8f 206 Gene3D G3DSA:3.30.420.10 3 204 8.8E-69 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_07055 31c1f3a09abac97881596be218947b8f 206 Pfam PF01351 Ribonuclease HII 16 190 3.9E-36 T 13-10-2018 IPR024567 Ribonuclease HII/HIII domain THITH_01695 b8b0e85df24fac42e41e1ef36137fd70 357 Gene3D G3DSA:1.10.287.470 91 150 3.5E-51 T 13-10-2018 THITH_01695 b8b0e85df24fac42e41e1ef36137fd70 357 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 32 335 1.1E-50 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THITH_01695 b8b0e85df24fac42e41e1ef36137fd70 357 Gene3D G3DSA:2.40.50.100 56 184 3.5E-51 T 13-10-2018 THITH_01695 b8b0e85df24fac42e41e1ef36137fd70 357 Gene3D G3DSA:2.40.420.20 266 333 3.5E-51 T 13-10-2018 THITH_01695 b8b0e85df24fac42e41e1ef36137fd70 357 Gene3D G3DSA:2.40.30.170 47 265 3.5E-51 T 13-10-2018 THITH_01695 b8b0e85df24fac42e41e1ef36137fd70 357 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 44 253 7.2E-20 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THITH_01695 b8b0e85df24fac42e41e1ef36137fd70 357 SUPERFAMILY SSF111369 48 259 1.05E-31 T 13-10-2018 THITH_01655 c5e891fa72f66944a02af733fb79f374 472 TIGRFAM TIGR02165 cas5_6_GSU0054: CRISPR-associated protein GSU0054/csb2, Dpsyc system 20 469 4.2E-57 T 13-10-2018 IPR019089 CRISPR-associated protein, GSU0054 THITH_01655 c5e891fa72f66944a02af733fb79f374 472 Pfam PF09609 CRISPR-associated protein, GSU0054 family (Cas_GSU0054) 22 468 2.6E-29 T 13-10-2018 IPR019089 CRISPR-associated protein, GSU0054 THITH_14310 b016f060a155983b8a188fd97411e18b 155 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 155 35.435 T 13-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 THITH_14310 b016f060a155983b8a188fd97411e18b 155 Gene3D G3DSA:1.10.455.10 2 154 1.6E-55 T 13-10-2018 IPR036823 Ribosomal protein S7 domain superfamily THITH_14310 b016f060a155983b8a188fd97411e18b 155 SUPERFAMILY SSF47973 1 148 3.01E-56 T 13-10-2018 IPR036823 Ribosomal protein S7 domain superfamily THITH_14310 b016f060a155983b8a188fd97411e18b 155 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 155 5.1E-65 T 13-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 THITH_14310 b016f060a155983b8a188fd97411e18b 155 PIRSF PIRSF002122 1 155 5.3E-55 T 13-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 THITH_14310 b016f060a155983b8a188fd97411e18b 155 Pfam PF00177 Ribosomal protein S7p/S5e 1 148 2.3E-64 T 13-10-2018 IPR023798 Ribosomal protein S7 domain THITH_09025 d976424c0ce1fcb3295bac911a452014 468 PRINTS PR00481 Cytosol aminopeptidase signature 305 325 1.7E-47 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THITH_09025 d976424c0ce1fcb3295bac911a452014 468 PRINTS PR00481 Cytosol aminopeptidase signature 283 304 1.7E-47 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THITH_09025 d976424c0ce1fcb3295bac911a452014 468 PRINTS PR00481 Cytosol aminopeptidase signature 246 267 1.7E-47 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THITH_09025 d976424c0ce1fcb3295bac911a452014 468 PRINTS PR00481 Cytosol aminopeptidase signature 333 348 1.7E-47 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THITH_09025 d976424c0ce1fcb3295bac911a452014 468 PRINTS PR00481 Cytosol aminopeptidase signature 224 241 1.7E-47 T 13-10-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 THITH_09025 d976424c0ce1fcb3295bac911a452014 468 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 309 316 - T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 THITH_09025 d976424c0ce1fcb3295bac911a452014 468 Gene3D G3DSA:3.40.630.10 136 460 3.9E-121 T 13-10-2018 THITH_09025 d976424c0ce1fcb3295bac911a452014 468 Gene3D G3DSA:3.40.220.10 4 133 1.4E-28 T 13-10-2018 THITH_09025 d976424c0ce1fcb3295bac911a452014 468 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 150 451 4.1E-103 T 13-10-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 THITH_09025 d976424c0ce1fcb3295bac911a452014 468 SUPERFAMILY SSF53187 144 458 3.14E-105 T 13-10-2018 THITH_00975 a3ea7711d56b56095b7cbfac97cd9abd 352 Gene3D G3DSA:3.40.50.300 10 205 7.6E-51 T 13-10-2018 THITH_00975 a3ea7711d56b56095b7cbfac97cd9abd 352 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 13 185 3.1E-42 T 13-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain THITH_00975 a3ea7711d56b56095b7cbfac97cd9abd 352 SUPERFAMILY SSF52540 11 183 4.7E-31 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_12980 597afc2ed790a3ab224bfe41a08a80fa 238 Gene3D G3DSA:3.30.460.80 90 170 6.5E-29 T 13-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12980 597afc2ed790a3ab224bfe41a08a80fa 238 Gene3D G3DSA:3.30.460.80 3 78 5.5E-11 T 13-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12980 597afc2ed790a3ab224bfe41a08a80fa 238 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 7 198 34.228 T 13-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12980 597afc2ed790a3ab224bfe41a08a80fa 238 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 30 190 1.8E-42 T 13-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12980 597afc2ed790a3ab224bfe41a08a80fa 238 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 117 178 1.0E-21 T 13-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12980 597afc2ed790a3ab224bfe41a08a80fa 238 SUPERFAMILY SSF143243 19 213 9.29E-52 T 13-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12980 597afc2ed790a3ab224bfe41a08a80fa 238 ProSitePatterns PS00542 Respiratory chain NADH dehydrogenase 30 Kd subunit signature. 151 172 - T 13-10-2018 IPR020396 NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_02695 353139ea160357abf8f04b3e53a40330 199 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 105 189 5.5E-25 T 13-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 THITH_02695 353139ea160357abf8f04b3e53a40330 199 SUPERFAMILY SSF46767 102 188 6.15E-23 T 13-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 THITH_02695 353139ea160357abf8f04b3e53a40330 199 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 151 157 - T 13-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 THITH_02695 353139ea160357abf8f04b3e53a40330 199 Gene3D G3DSA:1.10.10.10 102 193 6.9E-28 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_02695 353139ea160357abf8f04b3e53a40330 199 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 103 188 2.0E-22 T 13-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 THITH_16555 6a82248ef6217082cdc79c540c0e65cc 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 152 3.8E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_16555 6a82248ef6217082cdc79c540c0e65cc 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 3.8E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_16555 6a82248ef6217082cdc79c540c0e65cc 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 3.8E-8 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_16555 6a82248ef6217082cdc79c540c0e65cc 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 3.3E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_16555 6a82248ef6217082cdc79c540c0e65cc 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 184 201 3.3E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_16555 6a82248ef6217082cdc79c540c0e65cc 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 138 154 3.3E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_16555 6a82248ef6217082cdc79c540c0e65cc 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 3.3E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_16555 6a82248ef6217082cdc79c540c0e65cc 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 3.3E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_16555 6a82248ef6217082cdc79c540c0e65cc 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 236 3.3E-29 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_16555 6a82248ef6217082cdc79c540c0e65cc 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 21 250 2.0E-49 T 13-10-2018 THITH_16555 6a82248ef6217082cdc79c540c0e65cc 255 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 151 179 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THITH_16555 6a82248ef6217082cdc79c540c0e65cc 255 SUPERFAMILY SSF51735 15 252 2.05E-68 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_16555 6a82248ef6217082cdc79c540c0e65cc 255 Gene3D G3DSA:3.40.50.720 11 253 2.1E-66 T 13-10-2018 THITH_06415 dd36d00a83312ec48b42d1e06a5a2dbd 460 Pfam PF04055 Radical SAM superfamily 59 232 1.6E-16 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THITH_06415 dd36d00a83312ec48b42d1e06a5a2dbd 460 SUPERFAMILY SSF102114 6 448 2.75E-131 T 13-10-2018 THITH_06415 dd36d00a83312ec48b42d1e06a5a2dbd 460 Gene3D G3DSA:3.80.30.20 3 367 9.1E-118 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe THITH_06415 dd36d00a83312ec48b42d1e06a5a2dbd 460 TIGRFAM TIGR00538 hemN: oxygen-independent coproporphyrinogen III oxidase 7 460 2.3E-178 T 13-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 THITH_06415 dd36d00a83312ec48b42d1e06a5a2dbd 460 SMART SM00729 53 275 1.6E-46 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THITH_06415 dd36d00a83312ec48b42d1e06a5a2dbd 460 Pfam PF06969 HemN C-terminal domain 369 435 1.5E-9 T 13-10-2018 IPR010723 HemN, C-terminal THITH_06415 dd36d00a83312ec48b42d1e06a5a2dbd 460 PIRSF PIRSF000167 5 459 2.0E-157 T 13-10-2018 IPR004558 Oxygen-independent coproporphyrinogen III oxidase HemN GO:0004109|GO:0005737|GO:0006779|GO:0055114 KEGG: 00860+1.3.98.3|MetaCyc: PWY-5531 THITH_06415 dd36d00a83312ec48b42d1e06a5a2dbd 460 Gene3D G3DSA:1.10.10.920 368 460 4.2E-32 T 13-10-2018 THITH_06870 b88bd9f12444506fbeb606d7474b168d 142 Gene3D G3DSA:3.40.50.620 1 139 5.9E-37 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_06870 b88bd9f12444506fbeb606d7474b168d 142 Pfam PF00582 Universal stress protein family 4 140 2.6E-26 T 13-10-2018 IPR006016 UspA THITH_06870 b88bd9f12444506fbeb606d7474b168d 142 SUPERFAMILY SSF52402 3 140 2.09E-33 T 13-10-2018 THITH_06870 b88bd9f12444506fbeb606d7474b168d 142 PRINTS PR01438 Universal stress protein signature 100 112 1.1E-17 T 13-10-2018 IPR006015 Universal stress protein A THITH_06870 b88bd9f12444506fbeb606d7474b168d 142 PRINTS PR01438 Universal stress protein signature 1 18 1.1E-17 T 13-10-2018 IPR006015 Universal stress protein A THITH_06870 b88bd9f12444506fbeb606d7474b168d 142 PRINTS PR01438 Universal stress protein signature 118 140 1.1E-17 T 13-10-2018 IPR006015 Universal stress protein A THITH_09105 7f51effae5be7ae4a5af8b11add1d244 292 SUPERFAMILY SSF48576 10 275 3.02E-62 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily THITH_09105 7f51effae5be7ae4a5af8b11add1d244 292 Pfam PF00494 Squalene/phytoene synthase 20 271 7.0E-60 T 13-10-2018 THITH_09105 7f51effae5be7ae4a5af8b11add1d244 292 Gene3D G3DSA:1.10.600.10 3 264 2.5E-80 T 13-10-2018 IPR008949 Isoprenoid synthase domain superfamily THITH_09105 7f51effae5be7ae4a5af8b11add1d244 292 TIGRFAM TIGR03464 HpnC: squalene synthase HpnC 19 279 4.4E-91 T 13-10-2018 IPR017827 Hydroxysqualene synthase HpnC MetaCyc: PWY-7072 THITH_13935 ec55605854b51a96f735fe15bdcd85a0 158 TIGRFAM TIGR00754 bfr: bacterioferritin 1 155 2.7E-74 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THITH_13935 ec55605854b51a96f735fe15bdcd85a0 158 PRINTS PR00601 Bacterioferritin signature 3 22 6.4E-70 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THITH_13935 ec55605854b51a96f735fe15bdcd85a0 158 PRINTS PR00601 Bacterioferritin signature 86 106 6.4E-70 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THITH_13935 ec55605854b51a96f735fe15bdcd85a0 158 PRINTS PR00601 Bacterioferritin signature 23 43 6.4E-70 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THITH_13935 ec55605854b51a96f735fe15bdcd85a0 158 PRINTS PR00601 Bacterioferritin signature 128 149 6.4E-70 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THITH_13935 ec55605854b51a96f735fe15bdcd85a0 158 PRINTS PR00601 Bacterioferritin signature 65 85 6.4E-70 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THITH_13935 ec55605854b51a96f735fe15bdcd85a0 158 PRINTS PR00601 Bacterioferritin signature 44 64 6.4E-70 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THITH_13935 ec55605854b51a96f735fe15bdcd85a0 158 PRINTS PR00601 Bacterioferritin signature 107 127 6.4E-70 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THITH_13935 ec55605854b51a96f735fe15bdcd85a0 158 ProSitePatterns PS00549 Bacterioferritin signature. 1 19 - T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THITH_13935 ec55605854b51a96f735fe15bdcd85a0 158 Gene3D G3DSA:1.20.1260.10 1 158 2.4E-70 T 13-10-2018 IPR012347 Ferritin-like THITH_13935 ec55605854b51a96f735fe15bdcd85a0 158 SUPERFAMILY SSF47240 1 156 2.03E-55 T 13-10-2018 IPR009078 Ferritin-like superfamily THITH_13935 ec55605854b51a96f735fe15bdcd85a0 158 Pfam PF00210 Ferritin-like domain 10 144 8.2E-41 T 13-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 THITH_13935 ec55605854b51a96f735fe15bdcd85a0 158 PIRSF PIRSF002560 1 157 1.4E-71 T 13-10-2018 IPR002024 Bacterioferritin GO:0006826|GO:0006879|GO:0008199 THITH_09135 d06863be589c222aec55bf9055af1fc7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 211 4.7E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_09135 d06863be589c222aec55bf9055af1fc7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 23 40 4.7E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_09135 d06863be589c222aec55bf9055af1fc7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 100 111 4.7E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_09135 d06863be589c222aec55bf9055af1fc7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 190 4.7E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_09135 d06863be589c222aec55bf9055af1fc7 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 4.7E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_09135 d06863be589c222aec55bf9055af1fc7 259 SUPERFAMILY SSF51735 18 256 3.98E-49 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_09135 d06863be589c222aec55bf9055af1fc7 259 Pfam PF00106 short chain dehydrogenase 23 212 1.1E-33 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_09135 d06863be589c222aec55bf9055af1fc7 259 Gene3D G3DSA:3.40.50.720 10 256 8.1E-55 T 13-10-2018 THITH_10960 71cec1ed4b3521fe5de979011d9082d3 313 SUPERFAMILY SSF54909 17 281 4.94E-50 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel THITH_10960 71cec1ed4b3521fe5de979011d9082d3 313 Pfam PF07682 Sulphur oxygenase reductase 17 307 3.0E-112 T 13-10-2018 IPR011661 Sulphur oxygenase reductase KEGG: 00920+1.13.11.55|MetaCyc: PWY-5302 THITH_03770 22614e0554e67eb0947ad96d4054722b 620 SMART SM00382 381 561 1.2E-16 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_03770 22614e0554e67eb0947ad96d4054722b 620 Gene3D G3DSA:3.40.50.300 346 599 1.9E-98 T 13-10-2018 THITH_03770 22614e0554e67eb0947ad96d4054722b 620 Pfam PF00664 ABC transporter transmembrane region 38 309 6.8E-36 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 THITH_03770 22614e0554e67eb0947ad96d4054722b 620 Pfam PF00005 ABC transporter 372 521 2.6E-33 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_03770 22614e0554e67eb0947ad96d4054722b 620 SUPERFAMILY SSF90123 21 344 1.44E-61 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THITH_03770 22614e0554e67eb0947ad96d4054722b 620 Gene3D G3DSA:1.20.1560.10 27 344 6.3E-112 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THITH_03770 22614e0554e67eb0947ad96d4054722b 620 SUPERFAMILY SSF52540 347 591 3.26E-93 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_03770 22614e0554e67eb0947ad96d4054722b 620 ProSitePatterns PS00211 ABC transporters family signature. 493 507 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_13215 40d06dae3fc9fbff2b740ee6a78c9a9d 139 SUPERFAMILY SSF111038 1 139 4.84E-45 T 13-10-2018 IPR035917 YjbQ-like superfamily THITH_13215 40d06dae3fc9fbff2b740ee6a78c9a9d 139 Gene3D G3DSA:2.60.120.460 1 139 2.5E-41 T 13-10-2018 IPR035917 YjbQ-like superfamily THITH_13215 40d06dae3fc9fbff2b740ee6a78c9a9d 139 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 13 139 1.1E-40 T 13-10-2018 IPR001602 Uncharacterised protein family UPF0047 THITH_13215 40d06dae3fc9fbff2b740ee6a78c9a9d 139 Pfam PF01894 Uncharacterised protein family UPF0047 20 135 4.3E-38 T 13-10-2018 IPR001602 Uncharacterised protein family UPF0047 THITH_13215 40d06dae3fc9fbff2b740ee6a78c9a9d 139 PIRSF PIRSF004681 1 139 8.3E-50 T 13-10-2018 IPR001602 Uncharacterised protein family UPF0047 THITH_15925 3f0bfb22d31b2292d17a71acba7fc82d 216 Pfam PF04366 Las17-binding protein actin regulator 49 163 2.6E-28 T 13-10-2018 IPR007461 Ysc84 actin-binding domain THITH_08895 b9194181748cebeaabd229d196a2ba74 152 Pfam PF13801 Heavy-metal resistance 17 131 6.7E-12 T 13-10-2018 IPR025961 Heavy-metal resistance protein THITH_08895 b9194181748cebeaabd229d196a2ba74 152 Gene3D G3DSA:1.20.120.1490 34 141 4.8E-16 T 13-10-2018 THITH_03500 9c8fd3e823a84ec41011a58d10e4fad6 408 SMART SM00244 88 255 1.0E-29 T 13-10-2018 IPR001107 Band 7 domain THITH_03500 9c8fd3e823a84ec41011a58d10e4fad6 408 Pfam PF12221 Bacterial membrane protein N terminal 1 52 6.2E-15 T 13-10-2018 IPR020980 Menbrane protein HflK, N-terminal THITH_03500 9c8fd3e823a84ec41011a58d10e4fad6 408 SUPERFAMILY SSF117892 134 259 5.49E-19 T 13-10-2018 IPR036013 Band 7/SPFH domain superfamily THITH_03500 9c8fd3e823a84ec41011a58d10e4fad6 408 Pfam PF01145 SPFH domain / Band 7 family 92 269 7.9E-26 T 13-10-2018 IPR001107 Band 7 domain THITH_03500 9c8fd3e823a84ec41011a58d10e4fad6 408 TIGRFAM TIGR01933 hflK: HflK protein 90 357 5.0E-89 T 13-10-2018 IPR010201 HflK GO:0016021 THITH_03500 9c8fd3e823a84ec41011a58d10e4fad6 408 PRINTS PR00721 Stomatin signature 178 195 1.1E-8 T 13-10-2018 IPR001972 Stomatin family GO:0016020 THITH_03500 9c8fd3e823a84ec41011a58d10e4fad6 408 PRINTS PR00721 Stomatin signature 239 260 1.1E-8 T 13-10-2018 IPR001972 Stomatin family GO:0016020 THITH_03500 9c8fd3e823a84ec41011a58d10e4fad6 408 PRINTS PR00721 Stomatin signature 95 117 1.1E-8 T 13-10-2018 IPR001972 Stomatin family GO:0016020 THITH_03500 9c8fd3e823a84ec41011a58d10e4fad6 408 PRINTS PR00721 Stomatin signature 143 164 1.1E-8 T 13-10-2018 IPR001972 Stomatin family GO:0016020 THITH_03500 9c8fd3e823a84ec41011a58d10e4fad6 408 Gene3D G3DSA:3.30.479.30 130 245 8.5E-17 T 13-10-2018 THITH_01335 db448271fc411e44fd09b2af66ffd481 455 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 256 267 - T 13-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 THITH_01335 db448271fc411e44fd09b2af66ffd481 455 Gene3D G3DSA:3.40.605.10 9 447 1.0E-147 T 13-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 THITH_01335 db448271fc411e44fd09b2af66ffd481 455 Pfam PF00171 Aldehyde dehydrogenase family 5 451 5.5E-131 T 13-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 THITH_01335 db448271fc411e44fd09b2af66ffd481 455 SUPERFAMILY SSF53720 6 455 3.67E-134 T 13-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 THITH_01335 db448271fc411e44fd09b2af66ffd481 455 Gene3D G3DSA:3.40.309.10 232 421 1.0E-147 T 13-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 THITH_08145 60f41f74092f48b3cd92f412f293a67a 280 SUPERFAMILY SSF46785 1 109 6.32E-25 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_08145 60f41f74092f48b3cd92f412f293a67a 280 Gene3D G3DSA:1.10.10.10 1 86 1.3E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_08145 60f41f74092f48b3cd92f412f293a67a 280 Pfam PF03466 LysR substrate binding domain 90 277 3.9E-16 T 13-10-2018 IPR005119 LysR, substrate-binding THITH_08145 60f41f74092f48b3cd92f412f293a67a 280 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.7E-21 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_08145 60f41f74092f48b3cd92f412f293a67a 280 Gene3D G3DSA:3.40.190.10 87 180 5.6E-14 T 13-10-2018 THITH_08145 60f41f74092f48b3cd92f412f293a67a 280 SUPERFAMILY SSF53850 90 278 1.16E-21 T 13-10-2018 THITH_08145 60f41f74092f48b3cd92f412f293a67a 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.9E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_08145 60f41f74092f48b3cd92f412f293a67a 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.9E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_08145 60f41f74092f48b3cd92f412f293a67a 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.9E-8 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_09790 777fbd546896c22eefb67d3757c33951 163 Pfam PF01527 Transposase 2 53 1.2E-8 T 13-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 THITH_09790 777fbd546896c22eefb67d3757c33951 163 SUPERFAMILY SSF46689 2 52 4.84E-8 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_13745 81a6aa1fde40016de6f648f3b5d810c6 135 TIGRFAM TIGR03830 CxxCG_CxxCG_HTH: putative zinc finger/helix-turn-helix protein, YgiT family 6 132 2.8E-35 T 13-10-2018 IPR022452 Antitoxin MqsA THITH_13745 81a6aa1fde40016de6f648f3b5d810c6 135 Pfam PF15731 Antitoxin component of bacterial toxin-antitoxin system, MqsA 5 133 5.4E-37 T 13-10-2018 IPR032758 Antitoxin MqsA/HigA-2 THITH_13745 81a6aa1fde40016de6f648f3b5d810c6 135 SMART SM00530 75 129 7.0E-7 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_13745 81a6aa1fde40016de6f648f3b5d810c6 135 Gene3D G3DSA:1.10.260.40 67 133 4.0E-20 T 13-10-2018 THITH_13745 81a6aa1fde40016de6f648f3b5d810c6 135 Gene3D G3DSA:1.20.58.720 3 66 4.8E-7 T 13-10-2018 THITH_13745 81a6aa1fde40016de6f648f3b5d810c6 135 SUPERFAMILY SSF47413 68 129 1.1E-8 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 THITH_13745 81a6aa1fde40016de6f648f3b5d810c6 135 TIGRFAM TIGR03831 YgiT_finger: YgiT-type zinc finger domain 6 49 1.8E-6 T 13-10-2018 IPR022453 Zinc finger, MqsA-type THITH_04315 1a0a8b6c7f4d5aadac17886ab78486a5 358 Pfam PF01734 Patatin-like phospholipase 12 205 1.1E-18 T 13-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 THITH_04315 1a0a8b6c7f4d5aadac17886ab78486a5 358 Gene3D G3DSA:3.40.1090.20 9 93 8.1E-8 T 13-10-2018 THITH_04315 1a0a8b6c7f4d5aadac17886ab78486a5 358 Gene3D G3DSA:3.40.1090.10 94 264 3.1E-13 T 13-10-2018 THITH_04315 1a0a8b6c7f4d5aadac17886ab78486a5 358 SUPERFAMILY SSF52151 9 339 1.67E-51 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase THITH_15140 15f05f31786cc301fc66428b13edd301 444 Gene3D G3DSA:3.30.160.390 9 119 9.0E-9 T 13-10-2018 IPR038488 Integrase, DNA-binding domain superfamily THITH_15140 15f05f31786cc301fc66428b13edd301 444 SUPERFAMILY SSF56349 118 411 2.68E-43 T 13-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 THITH_15140 15f05f31786cc301fc66428b13edd301 444 Pfam PF00589 Phage integrase family 249 407 2.7E-19 T 13-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 THITH_15140 15f05f31786cc301fc66428b13edd301 444 Gene3D G3DSA:1.10.443.10 255 421 9.6E-26 T 13-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 THITH_15140 15f05f31786cc301fc66428b13edd301 444 Pfam PF13356 Arm DNA-binding domain 11 100 8.5E-11 T 13-10-2018 IPR025166 Integrase, DNA-binding domain THITH_14650 33feee40bdc1bc861867d308ae39e9f4 171 TIGRFAM TIGR03002 outer_YhbN_LptA: lipopolysaccharide transport periplasmic protein LptA 32 168 2.9E-31 T 13-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 THITH_14650 33feee40bdc1bc861867d308ae39e9f4 171 Pfam PF03968 OstA-like protein 42 149 2.8E-24 T 13-10-2018 IPR005653 Organic solvent tolerance-like, N-terminal THITH_14650 33feee40bdc1bc861867d308ae39e9f4 171 Hamap MF_01914 Lipopolysaccharide export system protein LptA [lptA]. 14 169 19.615 T 13-10-2018 IPR014340 Lipopolysaccharide export system protein LptA GO:0001530|GO:0015920|GO:0042597 THITH_14650 33feee40bdc1bc861867d308ae39e9f4 171 Gene3D G3DSA:2.60.450.10 36 171 6.6E-31 T 13-10-2018 THITH_10650 c4ef01c03e702fe980de3acaaab30505 415 TIGRFAM TIGR01834 PHA_synth_III_E: poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit 9 323 1.9E-69 T 13-10-2018 IPR010123 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit THITH_10650 c4ef01c03e702fe980de3acaaab30505 415 Pfam PF09712 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) 10 317 6.5E-100 T 13-10-2018 IPR010123 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit THITH_02285 318d5c96618c76f766b3c5cebe95f173 236 SMART SM00448 3 113 4.0E-29 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_02285 318d5c96618c76f766b3c5cebe95f173 236 SMART SM00850 136 233 3.0E-17 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 THITH_02285 318d5c96618c76f766b3c5cebe95f173 236 SUPERFAMILY SSF52172 2 128 3.7E-36 T 13-10-2018 IPR011006 CheY-like superfamily THITH_02285 318d5c96618c76f766b3c5cebe95f173 236 Pfam PF00072 Response regulator receiver domain 5 113 2.6E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_02285 318d5c96618c76f766b3c5cebe95f173 236 Gene3D G3DSA:2.40.50.1020 131 235 1.6E-5 T 13-10-2018 THITH_02285 318d5c96618c76f766b3c5cebe95f173 236 Gene3D G3DSA:3.40.50.2300 1 127 7.8E-35 T 13-10-2018 THITH_02285 318d5c96618c76f766b3c5cebe95f173 236 Pfam PF04397 LytTr DNA-binding domain 140 232 6.5E-18 T 13-10-2018 IPR007492 LytTR DNA-binding domain GO:0003677 THITH_14995 ed4385868dac45640bd95e13e443dc84 596 Pfam PF00593 TonB dependent receptor 179 593 6.9E-49 T 13-10-2018 IPR000531 TonB-dependent receptor-like, beta-barrel THITH_14995 ed4385868dac45640bd95e13e443dc84 596 SUPERFAMILY SSF56935 30 594 2.04E-119 T 13-10-2018 THITH_14995 ed4385868dac45640bd95e13e443dc84 596 Pfam PF07715 TonB-dependent Receptor Plug Domain 44 149 5.0E-26 T 13-10-2018 IPR012910 TonB-dependent receptor, plug domain THITH_14995 ed4385868dac45640bd95e13e443dc84 596 Gene3D G3DSA:2.40.170.20 161 595 5.0E-124 T 13-10-2018 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily THITH_14995 ed4385868dac45640bd95e13e443dc84 596 Gene3D G3DSA:2.170.130.10 29 154 2.3E-35 T 13-10-2018 IPR037066 TonB-dependent receptor, plug domain superfamily THITH_17125 38433d0524847f3bf5aaf30d45a9ccf4 73 Pfam PF11191 Protein of unknown function (DUF2782) 5 73 4.9E-20 T 13-10-2018 IPR021357 Protein of unknown function DUF2782 THITH_17125 38433d0524847f3bf5aaf30d45a9ccf4 73 Gene3D G3DSA:2.20.130.30 2 73 3.2E-20 T 13-10-2018 THITH_07725 c6b08ae024b7042ccca5f63078d33599 530 SUPERFAMILY SSF53649 4 524 4.25E-16 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 THITH_07725 c6b08ae024b7042ccca5f63078d33599 530 Gene3D G3DSA:3.40.720.10 1 278 4.0E-19 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 THITH_07725 c6b08ae024b7042ccca5f63078d33599 530 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 6 289 1.7E-12 T 13-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 THITH_02225 3b3ccb6cba89bdfc94e113b64142d114 86 SUPERFAMILY SSF143120 1 75 1.31E-10 T 13-10-2018 IPR036165 YefM-like superfamily THITH_02225 3b3ccb6cba89bdfc94e113b64142d114 86 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 4 67 3.3E-6 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THITH_08645 8fec1c0b96ef9ae70da69f6c63a7ff9e 172 Pfam PF09601 Protein of unknown function (DUF2459) 23 152 5.4E-5 T 13-10-2018 IPR011727 Conserved hypothetical protein CHP02117 THITH_10315 eab797626eebfdc0e0a04df99779d70a 314 Pfam PF14305 TupA-like ATPgrasp 23 266 1.4E-25 T 13-10-2018 IPR029465 TupA-like ATPgrasp protein THITH_03620 92f988edfd6f3a26700c6e09db883098 346 Gene3D G3DSA:3.30.930.10 13 249 1.5E-27 T 13-10-2018 THITH_03620 92f988edfd6f3a26700c6e09db883098 346 Pfam PF03099 Biotin/lipoate A/B protein ligase family 60 150 1.7E-4 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 THITH_03620 92f988edfd6f3a26700c6e09db883098 346 SUPERFAMILY SSF55681 9 237 2.24E-35 T 13-10-2018 THITH_13855 f860f364d7246803e6446ab22aba2bdc 409 Gene3D G3DSA:1.10.630.10 3 409 3.4E-132 T 13-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 THITH_13855 f860f364d7246803e6446ab22aba2bdc 409 PRINTS PR00359 B-class P450 signature 158 173 1.3E-56 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 THITH_13855 f860f364d7246803e6446ab22aba2bdc 409 PRINTS PR00359 B-class P450 signature 95 106 1.3E-56 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 THITH_13855 f860f364d7246803e6446ab22aba2bdc 409 PRINTS PR00359 B-class P450 signature 327 342 1.3E-56 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 THITH_13855 f860f364d7246803e6446ab22aba2bdc 409 PRINTS PR00359 B-class P450 signature 299 326 1.3E-56 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 THITH_13855 f860f364d7246803e6446ab22aba2bdc 409 PRINTS PR00359 B-class P450 signature 282 293 1.3E-56 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 THITH_13855 f860f364d7246803e6446ab22aba2bdc 409 PRINTS PR00359 B-class P450 signature 348 357 1.3E-56 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 THITH_13855 f860f364d7246803e6446ab22aba2bdc 409 PRINTS PR00359 B-class P450 signature 141 157 1.3E-56 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 THITH_13855 f860f364d7246803e6446ab22aba2bdc 409 PRINTS PR00359 B-class P450 signature 201 223 1.3E-56 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 THITH_13855 f860f364d7246803e6446ab22aba2bdc 409 PRINTS PR00359 B-class P450 signature 357 368 1.3E-56 T 13-10-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 THITH_13855 f860f364d7246803e6446ab22aba2bdc 409 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 350 359 - T 13-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 THITH_13855 f860f364d7246803e6446ab22aba2bdc 409 SUPERFAMILY SSF48264 20 407 2.75E-96 T 13-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 THITH_13855 f860f364d7246803e6446ab22aba2bdc 409 Pfam PF00067 Cytochrome P450 90 376 7.0E-24 T 13-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 THITH_07385 44d6eb268bde16d901c8732094aa78fe 618 Gene3D G3DSA:2.130.10.130 83 247 1.0E-5 T 13-10-2018 IPR028994 Integrin alpha, N-terminal Reactome: R-HSA-216083 THITH_07385 44d6eb268bde16d901c8732094aa78fe 618 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 115 187 5.8E-14 T 13-10-2018 THITH_07385 44d6eb268bde16d901c8732094aa78fe 618 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 274 326 2.3E-9 T 13-10-2018 THITH_07385 44d6eb268bde16d901c8732094aa78fe 618 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 427 507 2.4E-7 T 13-10-2018 THITH_07385 44d6eb268bde16d901c8732094aa78fe 618 Pfam PF07593 ASPIC and UnbV 541 608 1.7E-20 T 13-10-2018 IPR011519 ASPIC/UnbV THITH_07385 44d6eb268bde16d901c8732094aa78fe 618 SUPERFAMILY SSF69318 102 519 5.58E-55 T 13-10-2018 THITH_00535 901d9ac578c30460427b0472c06462a5 121 Gene3D G3DSA:3.30.2020.30 1 99 5.1E-30 T 13-10-2018 IPR038492 GBBH-like, N-terminal domain superfamily Reactome: R-HSA-71262 THITH_00535 901d9ac578c30460427b0472c06462a5 121 Pfam PF06155 Protein of unknown function (DUF971) 10 94 1.5E-29 T 13-10-2018 IPR010376 Gamma-butyrobetaine hydroxylase-like, N-terminal Reactome: R-HSA-71262 THITH_05275 2da745f806ab34b7cdac81b5e85c765c 320 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_05275 2da745f806ab34b7cdac81b5e85c765c 320 Gene3D G3DSA:3.40.50.300 1 244 2.6E-64 T 13-10-2018 THITH_05275 2da745f806ab34b7cdac81b5e85c765c 320 Pfam PF13732 Domain of unknown function (DUF4162) 217 304 3.8E-6 T 13-10-2018 IPR025302 Domain of unknown function DUF4162 THITH_05275 2da745f806ab34b7cdac81b5e85c765c 320 SMART SM00382 29 212 8.1E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_05275 2da745f806ab34b7cdac81b5e85c765c 320 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 14 306 4.2E-105 T 13-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 THITH_05275 2da745f806ab34b7cdac81b5e85c765c 320 SUPERFAMILY SSF52540 4 226 3.76E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_05275 2da745f806ab34b7cdac81b5e85c765c 320 Pfam PF00005 ABC transporter 20 163 1.2E-27 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_03575 8760016a526fbc5f25fca8648500baeb 474 Pfam PF01435 Peptidase family M48 70 254 1.9E-31 T 13-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 THITH_03575 8760016a526fbc5f25fca8648500baeb 474 Gene3D G3DSA:3.30.2010.10 82 147 2.8E-7 T 13-10-2018 THITH_03575 8760016a526fbc5f25fca8648500baeb 474 SUPERFAMILY SSF48452 296 414 4.98E-11 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_03575 8760016a526fbc5f25fca8648500baeb 474 Gene3D G3DSA:1.25.40.10 217 462 2.1E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_12345 69608bde0b99079bc160f16b5292e810 89 Pfam PF03319 Ethanolamine utilisation protein EutN/carboxysome 1 77 2.2E-19 T 13-10-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml THITH_12345 69608bde0b99079bc160f16b5292e810 89 ProDom PD012510 UTILIZATION ETHANOLAMINE CARBOXYSOME CCML PEPTIDE EUTN/CARBOXYSOME STRUCTURAL EUTN A B 10 79 4.0E-21 T 13-10-2018 IPR004992 Ethanolamine utilization protein EutN/carboxysome structural protein Ccml THITH_12345 69608bde0b99079bc160f16b5292e810 89 SUPERFAMILY SSF159133 1 82 5.1E-24 T 13-10-2018 IPR036677 EutN/Ccml superfamily THITH_12345 69608bde0b99079bc160f16b5292e810 89 Gene3D G3DSA:2.40.50.220 1 86 1.3E-28 T 13-10-2018 IPR036677 EutN/Ccml superfamily THITH_12345 69608bde0b99079bc160f16b5292e810 89 TIGRFAM TIGR02704 carboxysome_B: carboxysome peptide B 1 80 2.4E-40 T 13-10-2018 IPR014077 Carboxysome peptide B THITH_16210 9262fdc88fe6bf6c6c222e175e183e6c 201 Gene3D G3DSA:1.10.760.10 106 193 2.5E-16 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_16210 9262fdc88fe6bf6c6c222e175e183e6c 201 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 116 188 2.8E-6 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_16210 9262fdc88fe6bf6c6c222e175e183e6c 201 SUPERFAMILY SSF46626 112 192 9.15E-13 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_16210 9262fdc88fe6bf6c6c222e175e183e6c 201 PIRSF PIRSF000005 1 194 1.3E-32 T 13-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 THITH_16210 9262fdc88fe6bf6c6c222e175e183e6c 201 Gene3D G3DSA:1.10.760.10 29 105 6.6E-20 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_16210 9262fdc88fe6bf6c6c222e175e183e6c 201 SUPERFAMILY SSF46626 37 104 3.04E-15 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_16545 a6b61ef5eeb7fea5df54af0811244a7a 344 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 303 3.0E-112 T 13-10-2018 IPR017861 Kae1/TsaD family THITH_16545 a6b61ef5eeb7fea5df54af0811244a7a 344 Gene3D G3DSA:3.30.420.40 129 290 6.1E-123 T 13-10-2018 THITH_16545 a6b61ef5eeb7fea5df54af0811244a7a 344 Pfam PF00814 Glycoprotease family 24 303 3.1E-96 T 13-10-2018 IPR000905 Gcp-like domain THITH_16545 a6b61ef5eeb7fea5df54af0811244a7a 344 ProSitePatterns PS01016 Glycoprotease family signature. 96 116 - T 13-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 THITH_16545 a6b61ef5eeb7fea5df54af0811244a7a 344 SUPERFAMILY SSF53067 102 305 5.96E-40 T 13-10-2018 THITH_16545 a6b61ef5eeb7fea5df54af0811244a7a 344 Gene3D G3DSA:3.30.420.40 3 312 6.1E-123 T 13-10-2018 THITH_16545 a6b61ef5eeb7fea5df54af0811244a7a 344 SUPERFAMILY SSF53067 3 121 4.27E-29 T 13-10-2018 THITH_16545 a6b61ef5eeb7fea5df54af0811244a7a 344 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 1 329 64.222 T 13-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 THITH_16545 a6b61ef5eeb7fea5df54af0811244a7a 344 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 3 310 3.0E-126 T 13-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 THITH_16545 a6b61ef5eeb7fea5df54af0811244a7a 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 76 96 1.8E-50 T 13-10-2018 IPR017861 Kae1/TsaD family THITH_16545 a6b61ef5eeb7fea5df54af0811244a7a 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 260 269 1.8E-50 T 13-10-2018 IPR017861 Kae1/TsaD family THITH_16545 a6b61ef5eeb7fea5df54af0811244a7a 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 1.8E-50 T 13-10-2018 IPR017861 Kae1/TsaD family THITH_16545 a6b61ef5eeb7fea5df54af0811244a7a 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 97 116 1.8E-50 T 13-10-2018 IPR017861 Kae1/TsaD family THITH_16545 a6b61ef5eeb7fea5df54af0811244a7a 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 131 143 1.8E-50 T 13-10-2018 IPR017861 Kae1/TsaD family THITH_16545 a6b61ef5eeb7fea5df54af0811244a7a 344 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 154 175 1.8E-50 T 13-10-2018 IPR017861 Kae1/TsaD family THITH_10810 7fddba0e5c2d97e9b3f4ee9af362f0d4 168 SUPERFAMILY SSF46785 10 105 1.65E-19 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_10810 7fddba0e5c2d97e9b3f4ee9af362f0d4 168 SMART SM00344 13 123 1.6E-42 T 13-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 THITH_10810 7fddba0e5c2d97e9b3f4ee9af362f0d4 168 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 40 6.5E-16 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 THITH_10810 7fddba0e5c2d97e9b3f4ee9af362f0d4 168 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 40 59 6.5E-16 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 THITH_10810 7fddba0e5c2d97e9b3f4ee9af362f0d4 168 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 13 29 6.5E-16 T 13-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 THITH_10810 7fddba0e5c2d97e9b3f4ee9af362f0d4 168 Pfam PF13412 Winged helix-turn-helix DNA-binding 13 59 4.5E-21 T 13-10-2018 THITH_10810 7fddba0e5c2d97e9b3f4ee9af362f0d4 168 Pfam PF01037 Lrp/AsnC ligand binding domain 79 153 4.9E-24 T 13-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain THITH_10810 7fddba0e5c2d97e9b3f4ee9af362f0d4 168 ProSitePatterns PS00519 AsnC-type HTH domain signature. 31 57 - T 13-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site THITH_10810 7fddba0e5c2d97e9b3f4ee9af362f0d4 168 SUPERFAMILY SSF54909 73 163 2.77E-22 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel THITH_10810 7fddba0e5c2d97e9b3f4ee9af362f0d4 168 Gene3D G3DSA:3.30.70.920 66 151 1.5E-27 T 13-10-2018 THITH_10810 7fddba0e5c2d97e9b3f4ee9af362f0d4 168 Gene3D G3DSA:1.10.10.10 14 65 2.4E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_09610 8344d048dcd3aa0c6edb5483f04c39ff 251 SUPERFAMILY SSF53335 18 245 2.81E-43 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_09610 8344d048dcd3aa0c6edb5483f04c39ff 251 Gene3D G3DSA:3.40.50.150 16 247 1.8E-67 T 13-10-2018 THITH_09610 8344d048dcd3aa0c6edb5483f04c39ff 251 Hamap MF_00472 Ubiquinone biosynthesis O-methyltransferase [ubiG]. 16 248 36.211 T 13-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 THITH_09610 8344d048dcd3aa0c6edb5483f04c39ff 251 Pfam PF13489 Methyltransferase domain 54 218 3.7E-20 T 13-10-2018 THITH_09610 8344d048dcd3aa0c6edb5483f04c39ff 251 TIGRFAM TIGR01983 UbiG: 3-demethylubiquinone-9 3-O-methyltransferase 16 242 1.3E-77 T 13-10-2018 IPR010233 Ubiquinone biosynthesis O-methyltransferase GO:0006744|GO:0008425 KEGG: 00130+2.1.1.222+2.1.1.64|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-5870|MetaCyc: PWY-5871|MetaCyc: PWY-5872|MetaCyc: PWY-5873|MetaCyc: PWY-6708|MetaCyc: PWY-7230|MetaCyc: PWY-7233|Reactome: R-HSA-2142789 THITH_04805 17f9d08aa791a2e1ac727b9597fbb311 252 Gene3D G3DSA:3.40.1210.10 1 248 6.2E-96 T 13-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 THITH_04805 17f9d08aa791a2e1ac727b9597fbb311 252 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 250 42.011 T 13-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 THITH_04805 17f9d08aa791a2e1ac727b9597fbb311 252 SUPERFAMILY SSF64167 1 247 6.93E-87 T 13-10-2018 THITH_04805 17f9d08aa791a2e1ac727b9597fbb311 252 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 233 1.4E-69 T 13-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 THITH_04805 17f9d08aa791a2e1ac727b9597fbb311 252 Pfam PF01975 Survival protein SurE 3 183 6.7E-61 T 13-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 THITH_07200 ec70435cbfd536c9252815ff14bd31e9 827 Pfam PF12161 HsdM N-terminal domain 8 125 1.3E-13 T 13-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THITH_07200 ec70435cbfd536c9252815ff14bd31e9 827 Pfam PF02384 N-6 DNA Methylase 139 451 1.2E-97 T 13-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THITH_07200 ec70435cbfd536c9252815ff14bd31e9 827 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 163 179 5.9E-19 T 13-10-2018 THITH_07200 ec70435cbfd536c9252815ff14bd31e9 827 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 192 206 5.9E-19 T 13-10-2018 THITH_07200 ec70435cbfd536c9252815ff14bd31e9 827 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 263 275 5.9E-19 T 13-10-2018 THITH_07200 ec70435cbfd536c9252815ff14bd31e9 827 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 300 324 5.9E-19 T 13-10-2018 THITH_07200 ec70435cbfd536c9252815ff14bd31e9 827 SUPERFAMILY SSF53335 6 469 1.26E-120 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_07200 ec70435cbfd536c9252815ff14bd31e9 827 Gene3D G3DSA:1.20.1260.30 1 91 2.1E-16 T 13-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily THITH_07200 ec70435cbfd536c9252815ff14bd31e9 827 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 266 272 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THITH_07200 ec70435cbfd536c9252815ff14bd31e9 827 Gene3D G3DSA:3.40.50.150 140 433 5.3E-86 T 13-10-2018 THITH_07200 ec70435cbfd536c9252815ff14bd31e9 827 SUPERFAMILY SSF144292 652 740 1.57E-5 T 13-10-2018 THITH_05965 362f76e0b5456617ee922779f1264346 83 Gene3D G3DSA:1.10.1220.10 39 72 1.3E-6 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THITH_05965 362f76e0b5456617ee922779f1264346 83 SUPERFAMILY SSF47598 33 71 1.04E-10 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 THITH_05965 362f76e0b5456617ee922779f1264346 83 Pfam PF01402 Ribbon-helix-helix protein, copG family 34 71 4.3E-8 T 13-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 THITH_12610 3d67ac3301b9ab2379d0e562d5b267a0 298 SUPERFAMILY SSF56281 13 267 2.8E-49 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_12610 3d67ac3301b9ab2379d0e562d5b267a0 298 SMART SM00849 40 224 1.7E-16 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_12610 3d67ac3301b9ab2379d0e562d5b267a0 298 Pfam PF00753 Metallo-beta-lactamase superfamily 100 224 6.9E-10 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_12610 3d67ac3301b9ab2379d0e562d5b267a0 298 Gene3D G3DSA:3.60.15.10 11 251 3.5E-44 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_07965 700da255d9f5d093b320cb579bd4546f 229 Gene3D G3DSA:3.40.50.300 1 228 9.2E-75 T 13-10-2018 THITH_07965 700da255d9f5d093b320cb579bd4546f 229 TIGRFAM TIGR00017 cmk: cytidylate kinase 3 216 1.8E-69 T 13-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 THITH_07965 700da255d9f5d093b320cb579bd4546f 229 Pfam PF02224 Cytidylate kinase 6 220 1.1E-66 T 13-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 THITH_07965 700da255d9f5d093b320cb579bd4546f 229 SUPERFAMILY SSF52540 3 222 5.55E-45 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_07965 700da255d9f5d093b320cb579bd4546f 229 Hamap MF_00238 Cytidylate kinase [cmk]. 3 223 31.825 T 13-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 THITH_03790 81d427b9f549dd8cfdb237267468c121 476 Gene3D G3DSA:3.40.710.10 284 470 2.4E-55 T 13-10-2018 THITH_03790 81d427b9f549dd8cfdb237267468c121 476 Gene3D G3DSA:3.40.710.10 31 93 1.8E-6 T 13-10-2018 THITH_03790 81d427b9f549dd8cfdb237267468c121 476 Gene3D G3DSA:3.50.80.20 94 170 2.2E-16 T 13-10-2018 THITH_03790 81d427b9f549dd8cfdb237267468c121 476 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 30 458 1.1E-88 T 13-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THITH_03790 81d427b9f549dd8cfdb237267468c121 476 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 55 453 1.3E-65 T 13-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THITH_03790 81d427b9f549dd8cfdb237267468c121 476 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 296 318 8.4E-25 T 13-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THITH_03790 81d427b9f549dd8cfdb237267468c121 476 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 66 85 8.4E-25 T 13-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THITH_03790 81d427b9f549dd8cfdb237267468c121 476 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 431 444 8.4E-25 T 13-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THITH_03790 81d427b9f549dd8cfdb237267468c121 476 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 369 383 8.4E-25 T 13-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THITH_03790 81d427b9f549dd8cfdb237267468c121 476 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 354 368 8.4E-25 T 13-10-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 THITH_03790 81d427b9f549dd8cfdb237267468c121 476 SUPERFAMILY SSF56601 26 475 1.95E-96 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like THITH_15885 ccfad27e74cf4a2166c6fca059321c62 229 Gene3D G3DSA:3.20.20.70 3 218 1.4E-82 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_15885 ccfad27e74cf4a2166c6fca059321c62 229 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 34 48 - T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THITH_15885 ccfad27e74cf4a2166c6fca059321c62 229 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 137 159 - T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THITH_15885 ccfad27e74cf4a2166c6fca059321c62 229 PIRSF PIRSF001461 2 229 6.4E-100 T 13-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THITH_15885 ccfad27e74cf4a2166c6fca059321c62 229 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 6 207 3.1E-95 T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THITH_15885 ccfad27e74cf4a2166c6fca059321c62 229 SUPERFAMILY SSF51366 6 208 1.77E-72 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 THITH_15885 ccfad27e74cf4a2166c6fca059321c62 229 Pfam PF00834 Ribulose-phosphate 3 epimerase family 7 204 7.0E-91 T 13-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 THITH_11960 94c13ea8a017b6e6b2733941a1bb9ef0 113 Pfam PF04358 DsrC like protein 4 106 5.4E-33 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_11960 94c13ea8a017b6e6b2733941a1bb9ef0 113 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 3 106 2.8E-29 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_11960 94c13ea8a017b6e6b2733941a1bb9ef0 113 SUPERFAMILY SSF69721 2 106 6.28E-29 T 13-10-2018 IPR025526 DsrC-like domain superfamily THITH_11960 94c13ea8a017b6e6b2733941a1bb9ef0 113 PIRSF PIRSF006223 3 111 9.4E-33 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_11960 94c13ea8a017b6e6b2733941a1bb9ef0 113 Gene3D G3DSA:3.30.1420.10 1 38 3.6E-13 T 13-10-2018 THITH_11960 94c13ea8a017b6e6b2733941a1bb9ef0 113 Gene3D G3DSA:1.10.10.370 40 109 3.3E-19 T 13-10-2018 THITH_07645 eff2991a543b26d2fe34c19ff553eaca 350 PRINTS PR00111 Alpha/beta hydrolase fold signature 139 152 2.5E-7 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_07645 eff2991a543b26d2fe34c19ff553eaca 350 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 106 2.5E-7 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_07645 eff2991a543b26d2fe34c19ff553eaca 350 PRINTS PR00111 Alpha/beta hydrolase fold signature 255 269 2.5E-7 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_07645 eff2991a543b26d2fe34c19ff553eaca 350 Gene3D G3DSA:3.40.50.1820 37 320 7.9E-49 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_07645 eff2991a543b26d2fe34c19ff553eaca 350 SUPERFAMILY SSF53474 45 318 2.18E-36 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_07645 eff2991a543b26d2fe34c19ff553eaca 350 Pfam PF12146 Serine aminopeptidase, S33 61 299 4.4E-47 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 THITH_11795 a245dd46ab6e21289f676ae73e5c5e95 279 SMART SM00382 57 251 6.0E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_11795 a245dd46ab6e21289f676ae73e5c5e95 279 Pfam PF00005 ABC transporter 48 204 5.3E-31 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_11795 a245dd46ab6e21289f676ae73e5c5e95 279 ProSitePatterns PS00211 ABC transporters family signature. 176 190 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_11795 a245dd46ab6e21289f676ae73e5c5e95 279 SUPERFAMILY SSF52540 32 266 1.06E-58 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_11795 a245dd46ab6e21289f676ae73e5c5e95 279 Gene3D G3DSA:3.40.50.300 28 275 2.0E-64 T 13-10-2018 THITH_11795 a245dd46ab6e21289f676ae73e5c5e95 279 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 33 279 8.7E-125 T 13-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 THITH_17345 fe43258217216648993c22b9d1cded09 82 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 9 20 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_17345 fe43258217216648993c22b9d1cded09 82 Pfam PF00037 4Fe-4S binding domain 6 25 3.5E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_17345 fe43258217216648993c22b9d1cded09 82 Gene3D G3DSA:3.30.70.20 2 82 1.7E-35 T 13-10-2018 THITH_17345 fe43258217216648993c22b9d1cded09 82 SUPERFAMILY SSF54862 4 76 6.63E-20 T 13-10-2018 THITH_05340 20bd2177300155e175fc1f60a5519666 311 Pfam PF00174 Oxidoreductase molybdopterin binding domain 93 249 4.6E-30 T 13-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 THITH_05340 20bd2177300155e175fc1f60a5519666 311 SUPERFAMILY SSF56524 59 307 1.44E-90 T 13-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 THITH_05340 20bd2177300155e175fc1f60a5519666 311 Gene3D G3DSA:3.90.420.10 54 311 6.7E-105 T 13-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 THITH_05340 20bd2177300155e175fc1f60a5519666 311 Hamap MF_01206 Protein-methionine-sulfoxide reductase catalytic subunit MsrP [msrP]. 9 311 56.525 T 13-10-2018 IPR022867 Protein-methionine-sulfoxide reductase subunit MsrP GO:0016667|GO:0030091|GO:0043546|GO:0055114 THITH_11065 247a76ba07b6dd7165ba771beb8291aa 500 Pfam PF12161 HsdM N-terminal domain 6 136 4.9E-17 T 13-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain THITH_11065 247a76ba07b6dd7165ba771beb8291aa 500 SUPERFAMILY SSF53335 5 499 5.43E-129 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_11065 247a76ba07b6dd7165ba771beb8291aa 500 Gene3D G3DSA:1.20.1260.30 2 168 1.1E-29 T 13-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily THITH_11065 247a76ba07b6dd7165ba771beb8291aa 500 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 190 204 1.4E-19 T 13-10-2018 THITH_11065 247a76ba07b6dd7165ba771beb8291aa 500 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 275 287 1.4E-19 T 13-10-2018 THITH_11065 247a76ba07b6dd7165ba771beb8291aa 500 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 305 329 1.4E-19 T 13-10-2018 THITH_11065 247a76ba07b6dd7165ba771beb8291aa 500 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 166 182 1.4E-19 T 13-10-2018 THITH_11065 247a76ba07b6dd7165ba771beb8291aa 500 Pfam PF02384 N-6 DNA Methylase 145 466 3.3E-63 T 13-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 THITH_11065 247a76ba07b6dd7165ba771beb8291aa 500 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 278 284 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THITH_11065 247a76ba07b6dd7165ba771beb8291aa 500 Gene3D G3DSA:3.40.50.150 169 486 9.0E-76 T 13-10-2018 THITH_08775 38f5d21396320eeb69403a840b0b560a 150 Gene3D G3DSA:3.90.79.10 2 148 3.6E-28 T 13-10-2018 THITH_08775 38f5d21396320eeb69403a840b0b560a 150 SUPERFAMILY SSF55811 3 136 5.96E-23 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 THITH_08775 38f5d21396320eeb69403a840b0b560a 150 Pfam PF00293 NUDIX domain 8 115 2.7E-10 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 THITH_08775 38f5d21396320eeb69403a840b0b560a 150 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 13-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 THITH_10640 0a4a24378e56f55bae2eb7404cd4be4c 284 SUPERFAMILY SSF53328 89 284 7.2E-61 T 13-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THITH_10640 0a4a24378e56f55bae2eb7404cd4be4c 284 Gene3D G3DSA:3.30.70.260 2 87 4.3E-23 T 13-10-2018 THITH_10640 0a4a24378e56f55bae2eb7404cd4be4c 284 SUPERFAMILY SSF55021 7 84 1.29E-14 T 13-10-2018 THITH_10640 0a4a24378e56f55bae2eb7404cd4be4c 284 Pfam PF00551 Formyl transferase 89 263 2.5E-37 T 13-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 THITH_10640 0a4a24378e56f55bae2eb7404cd4be4c 284 Gene3D G3DSA:3.40.50.170 88 284 7.3E-71 T 13-10-2018 THITH_10640 0a4a24378e56f55bae2eb7404cd4be4c 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 41 53 5.3E-52 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 THITH_10640 0a4a24378e56f55bae2eb7404cd4be4c 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 111 138 5.3E-52 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 THITH_10640 0a4a24378e56f55bae2eb7404cd4be4c 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 235 257 5.3E-52 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 THITH_10640 0a4a24378e56f55bae2eb7404cd4be4c 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 9 35 5.3E-52 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 THITH_10640 0a4a24378e56f55bae2eb7404cd4be4c 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 257 282 5.3E-52 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 THITH_10640 0a4a24378e56f55bae2eb7404cd4be4c 284 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 89 111 5.3E-52 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 THITH_10640 0a4a24378e56f55bae2eb7404cd4be4c 284 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 8 283 6.4E-103 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 THITH_10640 0a4a24378e56f55bae2eb7404cd4be4c 284 PIRSF PIRSF036480 4 284 2.3E-109 T 13-10-2018 THITH_10640 0a4a24378e56f55bae2eb7404cd4be4c 284 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 4 283 45.632 T 13-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 THITH_11480 a3b9e54bed44c953a8722929597179a0 109 Gene3D G3DSA:3.30.2310.20 3 82 4.7E-8 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_11480 a3b9e54bed44c953a8722929597179a0 109 SUPERFAMILY SSF143011 18 80 5.1E-8 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_15665 9aae127959cddb839136844d187e1e5a 400 Gene3D G3DSA:3.40.50.1970 7 189 1.8E-43 T 13-10-2018 THITH_15665 9aae127959cddb839136844d187e1e5a 400 Pfam PF00465 Iron-containing alcohol dehydrogenase 12 386 1.6E-92 T 13-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 THITH_15665 9aae127959cddb839136844d187e1e5a 400 Gene3D G3DSA:1.20.1090.10 190 393 4.7E-44 T 13-10-2018 THITH_15665 9aae127959cddb839136844d187e1e5a 400 SUPERFAMILY SSF56796 4 391 2.49E-86 T 13-10-2018 THITH_11490 4b95e93d6dbb4a8eacc7bd0b3636c1b3 317 Pfam PF14267 Domain of unknown function (DUF4357) 244 297 1.2E-18 T 13-10-2018 IPR025579 Domain of unknown function DUF4357 THITH_08310 b8fcb766f07babc167ed2f695b2b68be 107 SUPERFAMILY SSF81301 13 104 5.56E-14 T 13-10-2018 THITH_08310 b8fcb766f07babc167ed2f695b2b68be 107 Pfam PF01909 Nucleotidyltransferase domain 26 90 3.4E-9 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THITH_08310 b8fcb766f07babc167ed2f695b2b68be 107 Gene3D G3DSA:3.30.460.10 12 107 3.7E-17 T 13-10-2018 THITH_09005 bc6e485e5e9deb60a363e9a5bc48f3ab 482 SUPERFAMILY SSF48695 46 241 1.28E-23 T 13-10-2018 IPR036280 Multiheme cytochrome superfamily THITH_09005 bc6e485e5e9deb60a363e9a5bc48f3ab 482 Gene3D G3DSA:1.10.1130.10 48 219 1.6E-9 T 13-10-2018 THITH_09005 bc6e485e5e9deb60a363e9a5bc48f3ab 482 Pfam PF13435 Cytochrome c554 and c-prime 50 138 4.3E-9 T 13-10-2018 IPR023155 Cytochrome c-552/4 THITH_00935 f8c67e098453b1d6e020a73cb884cfe5 89 Pfam PF01649 Ribosomal protein S20 2 83 1.5E-26 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_00935 f8c67e098453b1d6e020a73cb884cfe5 89 Gene3D G3DSA:1.20.58.110 1 86 9.0E-28 T 13-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_00935 f8c67e098453b1d6e020a73cb884cfe5 89 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 16.897 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_00935 f8c67e098453b1d6e020a73cb884cfe5 89 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 85 1.6E-25 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_00935 f8c67e098453b1d6e020a73cb884cfe5 89 SUPERFAMILY SSF46992 3 86 2.75E-29 T 13-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_00935 f8c67e098453b1d6e020a73cb884cfe5 89 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 87 3.0E-22 T 13-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_04170 019f02eb48be1a2ef2fca9657e73565a 172 Pfam PF03625 Domain of unknown function DUF302 66 116 1.1E-8 T 13-10-2018 IPR005180 Domain of unknown function DUF302 THITH_04170 019f02eb48be1a2ef2fca9657e73565a 172 SUPERFAMILY SSF103247 34 165 7.98E-16 T 13-10-2018 IPR035923 TT1751-like domain superfamily THITH_04170 019f02eb48be1a2ef2fca9657e73565a 172 Gene3D G3DSA:3.30.310.70 31 169 2.4E-13 T 13-10-2018 IPR035923 TT1751-like domain superfamily THITH_08155 ec9b041f6c5f936c9b0b02adf080d7fc 179 Pfam PF04982 HPP family 53 175 4.2E-46 T 13-10-2018 IPR007065 HPP THITH_13965 ba7beed4f95d1c602f506b2f04b33f8c 253 SMART SM00052 19 247 3.3E-34 T 13-10-2018 IPR001633 EAL domain THITH_13965 ba7beed4f95d1c602f506b2f04b33f8c 253 Gene3D G3DSA:3.20.20.450 15 253 6.5E-69 T 13-10-2018 IPR035919 EAL domain superfamily THITH_13965 ba7beed4f95d1c602f506b2f04b33f8c 253 SUPERFAMILY SSF141868 28 243 2.22E-59 T 13-10-2018 IPR035919 EAL domain superfamily THITH_13965 ba7beed4f95d1c602f506b2f04b33f8c 253 Pfam PF00563 EAL domain 28 242 7.5E-52 T 13-10-2018 IPR001633 EAL domain THITH_10615 b351931d06aad31aa0a1b26413fdefc6 222 Gene3D G3DSA:2.60.120.10 2 145 1.1E-43 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_10615 b351931d06aad31aa0a1b26413fdefc6 222 SUPERFAMILY SSF46785 146 215 7.96E-12 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_10615 b351931d06aad31aa0a1b26413fdefc6 222 Gene3D G3DSA:1.10.10.10 146 219 7.8E-23 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_10615 b351931d06aad31aa0a1b26413fdefc6 222 SMART SM00419 164 212 5.4E-10 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THITH_10615 b351931d06aad31aa0a1b26413fdefc6 222 Pfam PF13545 Crp-like helix-turn-helix domain 152 218 5.7E-14 T 13-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 THITH_10615 b351931d06aad31aa0a1b26413fdefc6 222 SUPERFAMILY SSF51206 6 146 3.01E-34 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like THITH_10615 b351931d06aad31aa0a1b26413fdefc6 222 Pfam PF00027 Cyclic nucleotide-binding domain 32 118 8.6E-20 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain THITH_10615 b351931d06aad31aa0a1b26413fdefc6 222 SMART SM00100 12 131 4.9E-20 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain THITH_11375 aa2407b8dca309573321023aaed0205b 271 Gene3D G3DSA:1.10.3470.10 38 268 1.0E-8 T 13-10-2018 IPR037294 ABC transporter, BtuC-like THITH_11375 aa2407b8dca309573321023aaed0205b 271 SUPERFAMILY SSF81345 3 256 9.94E-40 T 13-10-2018 IPR037294 ABC transporter, BtuC-like THITH_11375 aa2407b8dca309573321023aaed0205b 271 Pfam PF00950 ABC 3 transport family 4 255 4.0E-76 T 13-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 THITH_00280 42eeb88735cbd42e8c3782e391b02903 68 Gene3D G3DSA:3.30.160.250 1 66 1.5E-9 T 13-10-2018 THITH_00280 42eeb88735cbd42e8c3782e391b02903 68 SUPERFAMILY SSF143100 1 62 2.49E-12 T 13-10-2018 IPR035069 TTHA1013/TTHA0281-like THITH_08295 65aaa441536371e59f8de4dc6ccd8342 163 SMART SM00953 14 144 2.2E-14 T 13-10-2018 IPR014914 RES domain THITH_08295 65aaa441536371e59f8de4dc6ccd8342 163 Pfam PF08808 RES domain 2 141 5.1E-20 T 13-10-2018 IPR014914 RES domain THITH_04855 cc4f135dff7eab486972156b12a72a11 393 Gene3D G3DSA:1.10.287.470 172 191 1.4E-18 T 13-10-2018 THITH_04855 cc4f135dff7eab486972156b12a72a11 393 Gene3D G3DSA:2.40.420.20 298 382 1.9E-15 T 13-10-2018 THITH_04855 cc4f135dff7eab486972156b12a72a11 393 SUPERFAMILY SSF111369 160 303 4.97E-6 T 13-10-2018 THITH_04855 cc4f135dff7eab486972156b12a72a11 393 Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion 56 288 2.8E-15 T 13-10-2018 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain THITH_04855 cc4f135dff7eab486972156b12a72a11 393 SUPERFAMILY SSF111369 45 126 8.89E-7 T 13-10-2018 THITH_04855 cc4f135dff7eab486972156b12a72a11 393 Gene3D G3DSA:1.10.287.470 89 119 3.0E-10 T 13-10-2018 THITH_04855 cc4f135dff7eab486972156b12a72a11 393 Gene3D G3DSA:2.40.50.100 54 88 3.0E-10 T 13-10-2018 THITH_04855 cc4f135dff7eab486972156b12a72a11 393 TIGRFAM TIGR01730 RND_mfp: efflux transporter, RND family, MFP subunit 162 380 7.9E-34 T 13-10-2018 IPR006143 RND efflux pump, membrane fusion protein GO:0005215|GO:0016020|GO:0055085 THITH_04855 cc4f135dff7eab486972156b12a72a11 393 Gene3D G3DSA:2.40.30.170 229 289 1.4E-18 T 13-10-2018 THITH_04855 cc4f135dff7eab486972156b12a72a11 393 Gene3D G3DSA:2.40.50.100 192 228 1.4E-18 T 13-10-2018 THITH_05260 c013d0721a376bf8c8716e82e0db8511 129 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 11 123 1.1E-21 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 THITH_05260 c013d0721a376bf8c8716e82e0db8511 129 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 9 128 17.872 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 THITH_05260 c013d0721a376bf8c8716e82e0db8511 129 TIGRFAM TIGR00494 crcB: protein CrcB 11 126 1.0E-23 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 THITH_10385 17a0d959214c7415ad8684a10ea1e307 121 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 19 117 3.4E-23 T 13-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10385 17a0d959214c7415ad8684a10ea1e307 121 Gene3D G3DSA:1.20.58.1610 1 118 2.6E-25 T 13-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_11170 f4c4c5134d672c15b140c96b55063cdc 273 SUPERFAMILY SSF53474 1 270 4.63E-52 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_11170 f4c4c5134d672c15b140c96b55063cdc 273 Pfam PF00561 alpha/beta hydrolase fold 22 256 6.7E-22 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_11170 f4c4c5134d672c15b140c96b55063cdc 273 Gene3D G3DSA:3.40.50.1820 3 271 2.7E-57 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_04495 53af78f07d09900f52e58e8d7110da50 843 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 123 282 1.4E-7 T 13-10-2018 IPR000914 Solute-binding protein family 5 domain THITH_04495 53af78f07d09900f52e58e8d7110da50 843 SUPERFAMILY SSF53850 48 364 1.23E-23 T 13-10-2018 THITH_04495 53af78f07d09900f52e58e8d7110da50 843 Gene3D G3DSA:3.10.105.10 119 352 4.8E-20 T 13-10-2018 THITH_04620 c961083742fc9bab838f484766ab4d42 95 TIGRFAM TIGR02607 antidote_HigA: addiction module antidote protein, HigA family 3 83 1.8E-33 T 13-10-2018 IPR013430 Toxin-antitoxin system, antidote protein, HigA GO:0003677 THITH_04620 c961083742fc9bab838f484766ab4d42 95 SMART SM00530 12 68 2.3E-9 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_04620 c961083742fc9bab838f484766ab4d42 95 Pfam PF01381 Helix-turn-helix 13 66 5.3E-11 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_04620 c961083742fc9bab838f484766ab4d42 95 SUPERFAMILY SSF47413 8 88 4.51E-27 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 THITH_04620 c961083742fc9bab838f484766ab4d42 95 Gene3D G3DSA:1.10.260.40 2 94 1.6E-34 T 13-10-2018 THITH_15525 23ed26cd29a86cf9c6ce92f8671769ad 330 Pfam PF12224 Putative amidoligase enzyme 17 287 6.4E-60 T 13-10-2018 IPR022025 Putative amidoligase enzyme THITH_00230 cbf84b9bd93aefd12b9a23bf5e3939c1 589 Pfam PF00005 ABC transporter 373 525 5.0E-32 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_00230 cbf84b9bd93aefd12b9a23bf5e3939c1 589 Pfam PF00664 ABC transporter transmembrane region 75 250 5.7E-15 T 13-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 THITH_00230 cbf84b9bd93aefd12b9a23bf5e3939c1 589 Gene3D G3DSA:3.40.50.300 350 583 8.2E-77 T 13-10-2018 THITH_00230 cbf84b9bd93aefd12b9a23bf5e3939c1 589 SUPERFAMILY SSF52540 346 574 7.77E-70 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_00230 cbf84b9bd93aefd12b9a23bf5e3939c1 589 ProSitePatterns PS00211 ABC transporters family signature. 497 511 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_00230 cbf84b9bd93aefd12b9a23bf5e3939c1 589 SMART SM00382 382 571 1.3E-17 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_00230 cbf84b9bd93aefd12b9a23bf5e3939c1 589 SUPERFAMILY SSF90123 6 321 1.83E-32 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THITH_00230 cbf84b9bd93aefd12b9a23bf5e3939c1 589 Gene3D G3DSA:1.20.1560.10 5 333 1.4E-23 T 13-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 THITH_14100 03a5aa918029ec42c04a7aab52474a93 612 Pfam PF02687 FtsX-like permease family 510 605 4.5E-9 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THITH_02175 297a8cf9e0e49ce8eb6bc5460956259c 76 SUPERFAMILY SSF143120 4 44 4.05E-11 T 13-10-2018 IPR036165 YefM-like superfamily THITH_02175 297a8cf9e0e49ce8eb6bc5460956259c 76 Gene3D G3DSA:3.40.1620.10 1 40 6.1E-10 T 13-10-2018 THITH_02175 297a8cf9e0e49ce8eb6bc5460956259c 76 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 3 43 2.1E-11 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THITH_02175 297a8cf9e0e49ce8eb6bc5460956259c 76 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 43 2.4E-9 T 13-10-2018 THITH_05595 2c3cca4ff5b8d08d7f3a11c04b026d5a 146 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 7 143 9.865 T 13-10-2018 IPR022907 VapC family GO:0004540 THITH_05595 2c3cca4ff5b8d08d7f3a11c04b026d5a 146 Pfam PF01850 PIN domain 7 136 9.0E-15 T 13-10-2018 IPR002716 PIN domain THITH_05595 2c3cca4ff5b8d08d7f3a11c04b026d5a 146 Gene3D G3DSA:3.40.50.1010 7 136 1.2E-16 T 13-10-2018 THITH_05595 2c3cca4ff5b8d08d7f3a11c04b026d5a 146 SUPERFAMILY SSF88723 6 143 6.45E-18 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_00615 b42b7bee0969f3d0a9a5f06239928251 320 SUPERFAMILY SSF55298 193 315 1.09E-14 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 THITH_00615 b42b7bee0969f3d0a9a5f06239928251 320 Gene3D G3DSA:3.30.1330.40 193 318 2.5E-19 T 13-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 THITH_13630 c3490360842b304cd8624051c603c270 216 PIRSF PIRSF000705 3 205 6.2E-61 T 13-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 THITH_13630 c3490360842b304cd8624051c603c270 216 Gene3D G3DSA:3.40.50.300 8 202 1.5E-46 T 13-10-2018 THITH_13630 c3490360842b304cd8624051c603c270 216 Pfam PF01712 Deoxynucleoside kinase 10 197 8.1E-38 T 13-10-2018 IPR031314 Deoxynucleoside kinase domain THITH_13630 c3490360842b304cd8624051c603c270 216 SUPERFAMILY SSF52540 5 211 1.19E-43 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_12635 197f20a7a442a7beb36a2c91d3bdc4aa 169 SUPERFAMILY SSF75169 34 156 3.34E-20 T 13-10-2018 IPR027396 DsrEFH-like THITH_12635 197f20a7a442a7beb36a2c91d3bdc4aa 169 Pfam PF02635 DsrE/DsrF-like family 37 156 7.7E-17 T 13-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THITH_12635 197f20a7a442a7beb36a2c91d3bdc4aa 169 Gene3D G3DSA:3.40.1260.10 31 156 2.0E-13 T 13-10-2018 IPR027396 DsrEFH-like THITH_05285 59a6f5d6a0d2d3f1fbdd8752b6a9d392 245 Gene3D G3DSA:3.40.250.10 42 229 5.1E-29 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_05285 59a6f5d6a0d2d3f1fbdd8752b6a9d392 245 SUPERFAMILY SSF52821 67 178 6.16E-20 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_05285 59a6f5d6a0d2d3f1fbdd8752b6a9d392 245 SMART SM00450 56 184 2.1E-11 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_05285 59a6f5d6a0d2d3f1fbdd8752b6a9d392 245 Pfam PF00581 Rhodanese-like domain 68 178 4.4E-9 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_13175 d60f95efc55e9f4d9fcb37198169b821 159 Hamap MF_00023 SsrA-binding protein [smpB]. 1 159 75.328 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 THITH_13175 d60f95efc55e9f4d9fcb37198169b821 159 Gene3D G3DSA:2.40.280.10 7 135 1.7E-48 T 13-10-2018 IPR023620 Small protein B THITH_13175 d60f95efc55e9f4d9fcb37198169b821 159 SUPERFAMILY SSF74982 9 139 9.55E-52 T 13-10-2018 IPR023620 Small protein B THITH_13175 d60f95efc55e9f4d9fcb37198169b821 159 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 15 139 2.0E-46 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 THITH_13175 d60f95efc55e9f4d9fcb37198169b821 159 Pfam PF01668 SmpB protein 15 157 5.0E-59 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 THITH_13175 d60f95efc55e9f4d9fcb37198169b821 159 ProSitePatterns PS01317 SsrA-binding protein. 33 45 - T 13-10-2018 IPR020081 SsrA-binding protein, conserved site THITH_13175 d60f95efc55e9f4d9fcb37198169b821 159 TIGRFAM TIGR00086 smpB: SsrA-binding protein 15 157 6.0E-53 T 13-10-2018 IPR000037 SsrA-binding protein GO:0003723 THITH_09515 624baa7f363fe4011704b1dfb337e1c2 221 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 142 176 4.5E-5 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_09515 624baa7f363fe4011704b1dfb337e1c2 221 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 107 141 1.6E-9 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_09515 624baa7f363fe4011704b1dfb337e1c2 221 Gene3D G3DSA:3.40.50.20 1 92 4.2E-5 T 13-10-2018 THITH_09515 624baa7f363fe4011704b1dfb337e1c2 221 Gene3D G3DSA:2.160.10.10 93 213 2.0E-25 T 13-10-2018 THITH_09515 624baa7f363fe4011704b1dfb337e1c2 221 SUPERFAMILY SSF51161 5 203 4.85E-34 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily THITH_09515 624baa7f363fe4011704b1dfb337e1c2 221 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 4 205 1.4E-52 T 13-10-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like THITH_04330 c6bca002827541c3fcdb0830e05160ee 339 SMART SM00422 25 94 6.7E-18 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THITH_04330 c6bca002827541c3fcdb0830e05160ee 339 Gene3D G3DSA:1.10.1660.10 20 94 1.1E-25 T 13-10-2018 THITH_04330 c6bca002827541c3fcdb0830e05160ee 339 Pfam PF13411 MerR HTH family regulatory protein 26 93 1.4E-16 T 13-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 THITH_04330 c6bca002827541c3fcdb0830e05160ee 339 SUPERFAMILY SSF46955 25 93 4.58E-16 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily THITH_06210 f3dcc2d66a7be6fdeb8fef00d20e9496 516 ProSitePatterns PS01303 BCCT family of transporters signature. 318 327 - T 13-10-2018 IPR018093 BCCT transporter, conserved site THITH_06210 f3dcc2d66a7be6fdeb8fef00d20e9496 516 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 18 504 8.8E-195 T 13-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 THITH_06210 f3dcc2d66a7be6fdeb8fef00d20e9496 516 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 56 504 4.9E-162 T 13-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 THITH_03970 2edb61ff58287acf146d172ba3e67315 194 Gene3D G3DSA:3.90.1570.10 4 183 1.7E-19 T 13-10-2018 THITH_03970 2edb61ff58287acf146d172ba3e67315 194 Pfam PF05685 Putative restriction endonuclease 12 170 4.4E-35 T 13-10-2018 IPR008538 Domain of unknown function DUF820 THITH_03970 2edb61ff58287acf146d172ba3e67315 194 SUPERFAMILY SSF52980 4 176 3.65E-25 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_13785 4b1f982b9f3d80906f75de124489862d 1118 TIGRFAM TIGR02562 cas3_yersinia: CRISPR-associated helicase Cas3, subtype I-F/YPEST 2 1112 0.0 T 13-10-2018 IPR013395 Helicase Cas3, CRISPR-associated, Yersinia-type THITH_13785 4b1f982b9f3d80906f75de124489862d 1118 SUPERFAMILY SSF52540 427 868 4.12E-14 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01820 2dfa4475859b48d793d081ca4dc5f7b5 66 Gene3D G3DSA:3.40.50.300 4 65 5.0E-22 T 13-10-2018 THITH_01820 2dfa4475859b48d793d081ca4dc5f7b5 66 SUPERFAMILY SSF52540 5 55 1.32E-15 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01820 2dfa4475859b48d793d081ca4dc5f7b5 66 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 8 56 2.8E-19 T 13-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain THITH_14500 c700c81d81df826a64cce706bfc774cd 94 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 7 87 7.0E-24 T 13-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 THITH_14500 c700c81d81df826a64cce706bfc774cd 94 Pfam PF04999 Cell division protein FtsL 6 87 6.7E-24 T 13-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 THITH_14500 c700c81d81df826a64cce706bfc774cd 94 Hamap MF_00910 Cell division protein FtsL [ftsL]. 2 87 16.544 T 13-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 THITH_16140 293be26bf4768a0fa24ffd63930b1ee7 260 SUPERFAMILY SSF55486 48 242 2.27E-32 T 13-10-2018 THITH_16140 293be26bf4768a0fa24ffd63930b1ee7 260 Gene3D G3DSA:3.40.390.10 143 256 1.0E-31 T 13-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 THITH_16140 293be26bf4768a0fa24ffd63930b1ee7 260 Gene3D G3DSA:1.10.472.150 20 142 3.9E-39 T 13-10-2018 THITH_16140 293be26bf4768a0fa24ffd63930b1ee7 260 Pfam PF06167 Glucose-regulated metallo-peptidase M90 19 240 6.5E-73 T 13-10-2018 IPR010384 MtfA family THITH_04595 af6bb4e5e606a22ae5347b222dc6bd6f 230 SUPERFAMILY SSF56672 7 166 9.45E-13 T 13-10-2018 THITH_04595 af6bb4e5e606a22ae5347b222dc6bd6f 230 Pfam PF08388 Group II intron, maturase-specific domain 100 167 3.4E-15 T 13-10-2018 IPR013597 Group II intron, maturase-specific THITH_04595 af6bb4e5e606a22ae5347b222dc6bd6f 230 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 6 86 6.7E-14 T 13-10-2018 IPR000477 Reverse transcriptase domain THITH_14400 1a6061cf2b7caaf06b6463d9902ae438 201 Pfam PF01121 Dephospho-CoA kinase 4 178 1.0E-56 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 THITH_14400 1a6061cf2b7caaf06b6463d9902ae438 201 SUPERFAMILY SSF52540 3 187 3.91E-35 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14400 1a6061cf2b7caaf06b6463d9902ae438 201 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 189 2.4E-48 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 THITH_14400 1a6061cf2b7caaf06b6463d9902ae438 201 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 195 26.792 T 13-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 THITH_14400 1a6061cf2b7caaf06b6463d9902ae438 201 Gene3D G3DSA:3.40.50.300 1 200 1.7E-65 T 13-10-2018 THITH_03350 70b3a913228e486b1567df623ee63b87 141 Gene3D G3DSA:3.10.450.50 14 135 1.1E-33 T 13-10-2018 THITH_03350 70b3a913228e486b1567df623ee63b87 141 Hamap MF_00612 UPF0225 protein YchJ [ychJ]. 11 134 25.984 T 13-10-2018 IPR023006 Uncharacterised protein family UPF0225 THITH_03350 70b3a913228e486b1567df623ee63b87 141 SUPERFAMILY SSF54427 35 135 5.04E-33 T 13-10-2018 IPR032710 NTF2-like domain superfamily THITH_03115 0e5aa7758336078c79b5bc34f2b46dbf 347 Pfam PF05954 Phage late control gene D protein (GPD) 43 330 1.3E-16 T 13-10-2018 THITH_03115 0e5aa7758336078c79b5bc34f2b46dbf 347 Gene3D G3DSA:3.55.50.10 108 182 2.4E-5 T 13-10-2018 THITH_03115 0e5aa7758336078c79b5bc34f2b46dbf 347 SUPERFAMILY SSF69279 64 177 8.5E-18 T 13-10-2018 THITH_03590 36dd1e5d85b7bfd4dcccebf8fec77b3b 76 Pfam PF01206 Sulfurtransferase TusA 7 75 7.4E-23 T 13-10-2018 IPR001455 TusA-like domain THITH_03590 36dd1e5d85b7bfd4dcccebf8fec77b3b 76 Gene3D G3DSA:3.30.110.40 1 76 3.0E-30 T 13-10-2018 IPR036868 TusA-like domain superfamily THITH_03590 36dd1e5d85b7bfd4dcccebf8fec77b3b 76 SUPERFAMILY SSF64307 4 76 4.45E-24 T 13-10-2018 IPR036868 TusA-like domain superfamily THITH_03590 36dd1e5d85b7bfd4dcccebf8fec77b3b 76 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 8 32 - T 13-10-2018 IPR001455 TusA-like domain THITH_16615 6c1a58cafe0505e51752699d820a7f56 92 Gene3D G3DSA:3.30.2310.20 1 92 7.2E-37 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_16615 6c1a58cafe0505e51752699d820a7f56 92 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 3 92 3.2E-26 T 13-10-2018 IPR007711 Toxin HigB-1 THITH_16615 6c1a58cafe0505e51752699d820a7f56 92 SUPERFAMILY SSF143011 3 92 1.83E-14 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_13455 42ff9333a02f9e72ff260edecfcb8f43 83 Gene3D G3DSA:2.30.30.100 1 80 6.5E-32 T 13-10-2018 THITH_13455 42ff9333a02f9e72ff260edecfcb8f43 83 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 64 27.333 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 THITH_13455 42ff9333a02f9e72ff260edecfcb8f43 83 Pfam PF17209 Hfq protein 7 68 1.1E-30 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 THITH_13455 42ff9333a02f9e72ff260edecfcb8f43 83 SUPERFAMILY SSF50182 7 68 1.93E-23 T 13-10-2018 IPR010920 LSM domain superfamily THITH_13455 42ff9333a02f9e72ff260edecfcb8f43 83 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 64 2.3E-29 T 13-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 THITH_00175 6075ad0115ad36436796fd679b6d1a17 329 Pfam PF01370 NAD dependent epimerase/dehydratase family 1 249 4.1E-59 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 THITH_00175 6075ad0115ad36436796fd679b6d1a17 329 Gene3D G3DSA:3.90.25.10 170 303 6.3E-133 T 13-10-2018 THITH_00175 6075ad0115ad36436796fd679b6d1a17 329 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 1 321 2.3E-135 T 13-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 THITH_00175 6075ad0115ad36436796fd679b6d1a17 329 SUPERFAMILY SSF51735 1 323 1.16E-95 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_00175 6075ad0115ad36436796fd679b6d1a17 329 Gene3D G3DSA:3.40.50.720 1 249 6.3E-133 T 13-10-2018 THITH_15240 4ae41106465e1125ce279111f4e23699 202 Pfam PF00578 AhpC/TSA family 28 142 2.7E-31 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THITH_15240 4ae41106465e1125ce279111f4e23699 202 Gene3D G3DSA:3.40.30.10 16 169 3.3E-44 T 13-10-2018 THITH_15240 4ae41106465e1125ce279111f4e23699 202 SUPERFAMILY SSF52833 25 183 1.52E-42 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_09095 785cc8742348fa5e2469ba916b6a7917 229 Gene3D G3DSA:1.10.150.240 20 86 5.3E-53 T 13-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 THITH_09095 785cc8742348fa5e2469ba916b6a7917 229 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 185 5.1E-33 T 13-10-2018 THITH_09095 785cc8742348fa5e2469ba916b6a7917 229 Gene3D G3DSA:3.40.50.1000 8 193 5.3E-53 T 13-10-2018 IPR023214 HAD superfamily THITH_09095 785cc8742348fa5e2469ba916b6a7917 229 SUPERFAMILY SSF56784 6 204 1.5E-51 T 13-10-2018 IPR036412 HAD-like superfamily THITH_09095 785cc8742348fa5e2469ba916b6a7917 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 149 169 6.1E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_09095 785cc8742348fa5e2469ba916b6a7917 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 5 16 6.1E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_09095 785cc8742348fa5e2469ba916b6a7917 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 100 113 6.1E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_09095 785cc8742348fa5e2469ba916b6a7917 229 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 131 147 6.1E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_09095 785cc8742348fa5e2469ba916b6a7917 229 TIGRFAM TIGR01449 PGP_bact: phosphoglycolate phosphatase, bacterial 8 202 6.5E-55 T 13-10-2018 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic GO:0016791 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 THITH_09095 785cc8742348fa5e2469ba916b6a7917 229 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 88 181 2.6E-8 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_09095 785cc8742348fa5e2469ba916b6a7917 229 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 91 185 2.2E-10 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_10045 7caebccfa3a67684d30858941e6c7493 396 SUPERFAMILY SSF53756 12 385 2.3E-69 T 13-10-2018 THITH_10045 7caebccfa3a67684d30858941e6c7493 396 Gene3D G3DSA:3.40.50.2000 10 202 9.7E-13 T 13-10-2018 THITH_10045 7caebccfa3a67684d30858941e6c7493 396 Pfam PF00534 Glycosyl transferases group 1 214 362 7.2E-35 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 THITH_10045 7caebccfa3a67684d30858941e6c7493 396 Pfam PF13439 Glycosyltransferase Family 4 21 195 1.3E-13 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 THITH_10045 7caebccfa3a67684d30858941e6c7493 396 Gene3D G3DSA:3.40.50.2000 211 365 6.8E-42 T 13-10-2018 THITH_08005 bb24b0b468a28031b6d722918b10e7bf 259 Pfam PF02633 Creatinine amidohydrolase 1 242 2.4E-56 T 13-10-2018 IPR003785 Creatininase/formamide hydrolase KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 THITH_08005 bb24b0b468a28031b6d722918b10e7bf 259 Gene3D G3DSA:3.40.50.10310 1 248 5.1E-59 T 13-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 THITH_08005 bb24b0b468a28031b6d722918b10e7bf 259 SUPERFAMILY SSF102215 1 247 1.83E-59 T 13-10-2018 IPR024087 Creatininase-like superfamily KEGG: 00740+3.5.1.102|MetaCyc: PWY-6167 THITH_14125 dcd4e5dd655a7bcea405872ccf8906d1 291 Gene3D G3DSA:3.10.580.10 45 192 2.2E-51 T 13-10-2018 THITH_14125 dcd4e5dd655a7bcea405872ccf8906d1 291 SUPERFAMILY SSF54631 62 199 3.03E-30 T 13-10-2018 THITH_14125 dcd4e5dd655a7bcea405872ccf8906d1 291 SMART SM01091 203 281 1.4E-26 T 13-10-2018 IPR005170 Transporter-associated domain THITH_14125 dcd4e5dd655a7bcea405872ccf8906d1 291 Pfam PF00571 CBS domain 137 186 4.9E-5 T 13-10-2018 IPR000644 CBS domain THITH_14125 dcd4e5dd655a7bcea405872ccf8906d1 291 Pfam PF00571 CBS domain 65 123 2.0E-6 T 13-10-2018 IPR000644 CBS domain THITH_14125 dcd4e5dd655a7bcea405872ccf8906d1 291 SMART SM00116 74 123 0.064 T 13-10-2018 IPR000644 CBS domain THITH_14125 dcd4e5dd655a7bcea405872ccf8906d1 291 SMART SM00116 138 186 2.7 T 13-10-2018 IPR000644 CBS domain THITH_14125 dcd4e5dd655a7bcea405872ccf8906d1 291 Gene3D G3DSA:3.30.465.10 193 281 1.7E-27 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 THITH_14125 dcd4e5dd655a7bcea405872ccf8906d1 291 Pfam PF03471 Transporter associated domain 206 279 2.7E-20 T 13-10-2018 IPR005170 Transporter-associated domain THITH_14125 dcd4e5dd655a7bcea405872ccf8906d1 291 SUPERFAMILY SSF56176 202 284 1.2E-21 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 THITH_00040 04c2b270460266ac0f8db28c922b1750 263 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 4 246 7.0E-22 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase THITH_00040 04c2b270460266ac0f8db28c922b1750 263 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 27 36 - T 13-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 THITH_00040 04c2b270460266ac0f8db28c922b1750 263 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 253 5.4E-82 T 13-10-2018 THITH_00040 04c2b270460266ac0f8db28c922b1750 263 SUPERFAMILY SSF56219 2 255 4.32E-76 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily THITH_00040 04c2b270460266ac0f8db28c922b1750 263 Gene3D G3DSA:3.60.10.10 1 255 2.9E-73 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily THITH_00040 04c2b270460266ac0f8db28c922b1750 263 ProSitePatterns PS00728 AP endonucleases family 1 signature 3. 210 221 - T 13-10-2018 IPR020848 AP endonuclease 1, conserved site GO:0003677|GO:0004519|GO:0005622|GO:0006281 Reactome: R-HSA-110357|Reactome: R-HSA-110362|Reactome: R-HSA-110373|Reactome: R-HSA-5651801|Reactome: R-HSA-73930|Reactome: R-HSA-73933 THITH_00040 04c2b270460266ac0f8db28c922b1750 263 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 1 254 4.4E-75 T 13-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 THITH_01730 94f992083329cb1d768b4ec0827dfb32 213 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 183 1.1E-47 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal THITH_01730 94f992083329cb1d768b4ec0827dfb32 213 SUPERFAMILY SSF53639 2 211 1.26E-66 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily THITH_01730 94f992083329cb1d768b4ec0827dfb32 213 SMART SM01007 10 184 1.9E-67 T 13-10-2018 IPR001303 Class II aldolase/adducin N-terminal THITH_01730 94f992083329cb1d768b4ec0827dfb32 213 Gene3D G3DSA:3.40.225.10 4 213 1.3E-75 T 13-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily THITH_12750 aef14817f894ded2c5f7770c7649a650 201 Pfam PF13548 Domain of unknown function (DUF4126) 13 186 1.4E-48 T 13-10-2018 IPR025196 Domain of unknown function DUF4126 THITH_12010 c3870aa87e0579ee44e22fb1bbe6d1c0 250 SUPERFAMILY SSF103501 4 232 2.22E-46 T 13-10-2018 IPR036197 NarG-like superfamily THITH_12010 c3870aa87e0579ee44e22fb1bbe6d1c0 250 Gene3D G3DSA:1.20.950.20 46 218 1.3E-17 T 13-10-2018 THITH_12010 c3870aa87e0579ee44e22fb1bbe6d1c0 250 Pfam PF02665 Nitrate reductase gamma subunit 65 211 2.7E-13 T 13-10-2018 IPR023234 NarG-like domain THITH_12125 651122cba31df9f73e314cd89754d34f 220 Gene3D G3DSA:1.20.1440.120 75 220 4.4E-24 T 13-10-2018 THITH_12125 651122cba31df9f73e314cd89754d34f 220 Pfam PF11967 Recombination protein O N terminal 10 70 1.8E-11 T 13-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal THITH_12125 651122cba31df9f73e314cd89754d34f 220 SUPERFAMILY SSF50249 9 70 2.91E-8 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_12125 651122cba31df9f73e314cd89754d34f 220 Gene3D G3DSA:2.40.50.140 6 73 1.2E-15 T 13-10-2018 THITH_11045 4d86308dad56e2e06058d3a642a76156 83 Gene3D G3DSA:1.10.1220.170 41 83 5.5E-15 T 13-10-2018 THITH_11045 4d86308dad56e2e06058d3a642a76156 83 SUPERFAMILY SSF143120 2 80 6.67E-24 T 13-10-2018 IPR036165 YefM-like superfamily THITH_11045 4d86308dad56e2e06058d3a642a76156 83 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 2 74 5.2E-22 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THITH_11045 4d86308dad56e2e06058d3a642a76156 83 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 3 56 8.1E-13 T 13-10-2018 THITH_11045 4d86308dad56e2e06058d3a642a76156 83 Gene3D G3DSA:3.40.1620.10 1 40 8.5E-15 T 13-10-2018 THITH_01880 fd07e90b5f3e337a3b5e293560147e18 233 Gene3D G3DSA:3.30.2010.10 139 232 1.0E-15 T 13-10-2018 THITH_01880 fd07e90b5f3e337a3b5e293560147e18 233 Pfam PF01863 Protein of unknown function DUF45 23 229 5.7E-57 T 13-10-2018 IPR002725 Protein of unknown function DUF45 THITH_08325 22016ff88f337a700d19cb089158c9f4 86 Pfam PF05685 Putative restriction endonuclease 1 60 2.2E-14 T 13-10-2018 IPR008538 Domain of unknown function DUF820 THITH_08325 22016ff88f337a700d19cb089158c9f4 86 Gene3D G3DSA:3.90.1570.10 1 64 1.4E-13 T 13-10-2018 THITH_08325 22016ff88f337a700d19cb089158c9f4 86 SUPERFAMILY SSF52980 1 49 1.5E-13 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_11335 5faa953b09608c3845304004ba095b6d 264 SMART SM00563 68 179 9.6E-29 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 THITH_11335 5faa953b09608c3845304004ba095b6d 264 SUPERFAMILY SSF69593 37 241 2.88E-28 T 13-10-2018 THITH_11335 5faa953b09608c3845304004ba095b6d 264 Pfam PF01553 Acyltransferase 57 176 2.4E-22 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 THITH_05785 0c1571f579e85d10b71a5b5fa37daf6b 532 SUPERFAMILY SSF56235 12 149 2.57E-13 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_05785 0c1571f579e85d10b71a5b5fa37daf6b 532 Pfam PF00733 Asparagine synthase 187 262 1.5E-9 T 13-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 THITH_05785 0c1571f579e85d10b71a5b5fa37daf6b 532 SUPERFAMILY SSF52402 161 433 6.16E-19 T 13-10-2018 THITH_05785 0c1571f579e85d10b71a5b5fa37daf6b 532 Gene3D G3DSA:3.60.20.10 37 162 1.9E-10 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_07705 7acb521c0ccb8bd0a476d1370e5570fa 183 Pfam PF01066 CDP-alcohol phosphatidyltransferase 4 72 4.1E-16 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THITH_07705 7acb521c0ccb8bd0a476d1370e5570fa 183 Gene3D G3DSA:1.20.120.1760 2 182 3.9E-14 T 13-10-2018 THITH_07705 7acb521c0ccb8bd0a476d1370e5570fa 183 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 50 72 - T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THITH_07705 7acb521c0ccb8bd0a476d1370e5570fa 183 PIRSF PIRSF000847 1 183 3.3E-42 T 13-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 THITH_07705 7acb521c0ccb8bd0a476d1370e5570fa 183 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 4 179 1.6E-53 T 13-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 THITH_11120 1e3cf47ddd9bc52079d168453ae72089 119 Pfam PF09722 Protein of unknown function (DUF2384) 69 117 9.1E-13 T 13-10-2018 IPR024467 Domain of unknown function DUF2384 THITH_15680 f885acc1f9c878e8874e00632c7a5697 153 TIGRFAM TIGR00576 dut: dUTP diphosphatase 13 152 3.6E-47 T 13-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 THITH_15680 f885acc1f9c878e8874e00632c7a5697 153 Pfam PF00692 dUTPase 18 151 2.0E-39 T 13-10-2018 IPR029054 dUTPase-like THITH_15680 f885acc1f9c878e8874e00632c7a5697 153 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 8 152 32.979 T 13-10-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 THITH_15680 f885acc1f9c878e8874e00632c7a5697 153 Gene3D G3DSA:2.70.40.10 3 152 3.4E-52 T 13-10-2018 IPR036157 dUTPase-like superfamily THITH_15680 f885acc1f9c878e8874e00632c7a5697 153 SUPERFAMILY SSF51283 7 152 4.84E-53 T 13-10-2018 IPR036157 dUTPase-like superfamily THITH_07155 26b622a13b5d722c695630057c3a591b 483 Pfam PF02386 Cation transport protein 38 477 5.7E-85 T 13-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 THITH_07155 26b622a13b5d722c695630057c3a591b 483 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 84 466 7.0E-110 T 13-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 THITH_07155 26b622a13b5d722c695630057c3a591b 483 PIRSF PIRSF006247 1 483 3.0E-177 T 13-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 THITH_15330 4f35fd95c475ed5f1489772b100ec0e9 297 Gene3D G3DSA:3.40.50.150 106 297 3.6E-55 T 13-10-2018 THITH_15330 4f35fd95c475ed5f1489772b100ec0e9 297 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 5 290 3.2E-65 T 13-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 THITH_15330 4f35fd95c475ed5f1489772b100ec0e9 297 PIRSF PIRSF000401 1 297 3.3E-70 T 13-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 THITH_15330 4f35fd95c475ed5f1489772b100ec0e9 297 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 296 29.852 T 13-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 THITH_15330 4f35fd95c475ed5f1489772b100ec0e9 297 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 4 296 1.9E-74 T 13-10-2018 THITH_15330 4f35fd95c475ed5f1489772b100ec0e9 297 SUPERFAMILY SSF53335 84 289 3.44E-41 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_05330 b4b5088e31a51b3179961e527049397c 392 Gene3D G3DSA:2.40.370.10 249 387 2.6E-40 T 13-10-2018 IPR023374 AttH-like domain superfamily THITH_05330 b4b5088e31a51b3179961e527049397c 392 SUPERFAMILY SSF159245 46 382 2.62E-96 T 13-10-2018 THITH_05330 b4b5088e31a51b3179961e527049397c 392 Pfam PF07143 CrtC N-terminal lipocalin domain 70 245 2.7E-54 T 13-10-2018 IPR010791 AttH domain THITH_05330 b4b5088e31a51b3179961e527049397c 392 Gene3D G3DSA:2.40.370.10 57 248 3.4E-66 T 13-10-2018 IPR023374 AttH-like domain superfamily THITH_05330 b4b5088e31a51b3179961e527049397c 392 Pfam PF17186 Lipocalin-like domain 248 382 2.4E-40 T 13-10-2018 THITH_03290 8a5f5d75c5fb7b9daf1f36b8e2923dc3 96 Gene3D G3DSA:3.40.50.1820 1 90 2.0E-15 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_03290 8a5f5d75c5fb7b9daf1f36b8e2923dc3 96 Pfam PF06500 Alpha/beta hydrolase of unknown function (DUF1100) 2 81 3.5E-4 T 13-10-2018 IPR010520 UPF0255 family THITH_03290 8a5f5d75c5fb7b9daf1f36b8e2923dc3 96 SUPERFAMILY SSF53474 1 84 1.3E-7 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_12760 43e88e00c6c9a2cefe9a371a9dee3999 77 Gene3D G3DSA:3.30.70.100 6 71 5.9E-8 T 13-10-2018 THITH_12760 43e88e00c6c9a2cefe9a371a9dee3999 77 SUPERFAMILY SSF55008 3 75 1.7E-7 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 THITH_05230 c342c312073c7d5ac6e920d0ad24f38a 569 Pfam PF00144 Beta-lactamase 48 363 1.8E-58 T 13-10-2018 IPR001466 Beta-lactamase-related THITH_05230 c342c312073c7d5ac6e920d0ad24f38a 569 Gene3D G3DSA:3.40.710.10 40 373 1.7E-77 T 13-10-2018 THITH_05230 c342c312073c7d5ac6e920d0ad24f38a 569 SUPERFAMILY SSF56601 37 370 1.88E-75 T 13-10-2018 IPR012338 Beta-lactamase/transpeptidase-like THITH_14910 54650acca086587ab339ff23c655b1ca 352 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 7 350 51.594 T 13-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 THITH_14910 54650acca086587ab339ff23c655b1ca 352 SUPERFAMILY SSF51726 4 351 4.01E-120 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 THITH_14910 54650acca086587ab339ff23c655b1ca 352 Gene3D G3DSA:3.20.20.210 1 352 3.2E-158 T 13-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 THITH_14910 54650acca086587ab339ff23c655b1ca 352 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 23 32 - T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 THITH_14910 54650acca086587ab339ff23c655b1ca 352 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 143 159 - T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 THITH_14910 54650acca086587ab339ff23c655b1ca 352 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 6 349 1.4E-141 T 13-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 THITH_14910 54650acca086587ab339ff23c655b1ca 352 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 10 347 4.9E-134 T 13-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 THITH_13625 0d9df6f9deb1da768401a83a515272e6 263 SUPERFAMILY SSF51621 2 255 6.67E-91 T 13-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 THITH_13625 0d9df6f9deb1da768401a83a515272e6 263 Gene3D G3DSA:3.20.20.60 1 263 1.8E-95 T 13-10-2018 THITH_13625 0d9df6f9deb1da768401a83a515272e6 263 Pfam PF02548 Ketopantoate hydroxymethyltransferase 2 255 2.3E-98 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 THITH_13625 0d9df6f9deb1da768401a83a515272e6 263 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 3 262 38.329 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 THITH_13625 0d9df6f9deb1da768401a83a515272e6 263 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 2 257 5.2E-89 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 THITH_13625 0d9df6f9deb1da768401a83a515272e6 263 PIRSF PIRSF000388 1 263 9.8E-89 T 13-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 THITH_12520 65a0916fff8a615258724cf194add63f 352 Gene3D G3DSA:3.20.20.70 106 248 4.7E-8 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_12520 65a0916fff8a615258724cf194add63f 352 SUPERFAMILY SSF102114 113 204 6.02E-6 T 13-10-2018 THITH_12520 65a0916fff8a615258724cf194add63f 352 PIRSF PIRSF004869 23 349 2.9E-73 T 13-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted THITH_12520 65a0916fff8a615258724cf194add63f 352 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 23 5.0E-4 T 13-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THITH_00085 7fdd04a03d32b9a9c7925180e4f65ace 230 Pfam PF13525 Outer membrane lipoprotein 84 224 5.7E-20 T 13-10-2018 IPR039565 Outer membrane lipoprotein BamD-like THITH_00085 7fdd04a03d32b9a9c7925180e4f65ace 230 Gene3D G3DSA:1.25.40.10 57 230 1.3E-16 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_15175 b7e50d62a56a0f3963ce6b8c86291d29 354 Pfam PF00990 Diguanylate cyclase, GGDEF domain 181 337 7.6E-45 T 13-10-2018 IPR000160 GGDEF domain THITH_15175 b7e50d62a56a0f3963ce6b8c86291d29 354 SMART SM00267 169 341 3.6E-53 T 13-10-2018 IPR000160 GGDEF domain THITH_15175 b7e50d62a56a0f3963ce6b8c86291d29 354 SUPERFAMILY SSF55073 185 342 8.63E-47 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_15175 b7e50d62a56a0f3963ce6b8c86291d29 354 Gene3D G3DSA:3.30.70.270 175 343 2.7E-55 T 13-10-2018 THITH_15175 b7e50d62a56a0f3963ce6b8c86291d29 354 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 178 339 2.1E-47 T 13-10-2018 IPR000160 GGDEF domain THITH_12865 cfd3f44295a8335aa1236ed1b4053156 267 Gene3D G3DSA:3.60.20.10 2 234 1.7E-26 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_12865 cfd3f44295a8335aa1236ed1b4053156 267 Pfam PF00227 Proteasome subunit 4 195 1.4E-7 T 13-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 THITH_12865 cfd3f44295a8335aa1236ed1b4053156 267 SUPERFAMILY SSF56235 2 241 1.55E-33 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_12865 cfd3f44295a8335aa1236ed1b4053156 267 PIRSF PIRSF009120 1 250 2.0E-101 T 13-10-2018 IPR016545 Uncharacterised conserved protein UCP009120, proteasome-type protease, Sll0069 THITH_15630 8aa84e5f4a51377427f36fe06f0c9f71 220 Gene3D G3DSA:3.30.1330.60 77 219 2.1E-49 T 13-10-2018 IPR036737 OmpA-like domain superfamily THITH_15630 8aa84e5f4a51377427f36fe06f0c9f71 220 SUPERFAMILY SSF103088 100 217 7.72E-38 T 13-10-2018 IPR036737 OmpA-like domain superfamily THITH_15630 8aa84e5f4a51377427f36fe06f0c9f71 220 Pfam PF13488 Glycine zipper 36 83 1.3E-14 T 13-10-2018 IPR039567 Glycine zipper domain THITH_15630 8aa84e5f4a51377427f36fe06f0c9f71 220 Pfam PF00691 OmpA family 113 208 2.7E-22 T 13-10-2018 IPR006665 OmpA-like domain THITH_15630 8aa84e5f4a51377427f36fe06f0c9f71 220 PRINTS PR01021 OMPA domain signature 144 159 3.8E-16 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THITH_15630 8aa84e5f4a51377427f36fe06f0c9f71 220 PRINTS PR01021 OMPA domain signature 159 175 3.8E-16 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THITH_15630 8aa84e5f4a51377427f36fe06f0c9f71 220 PRINTS PR01021 OMPA domain signature 114 136 3.8E-16 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THITH_04950 405f3c241abc727ae56f9450a868871e 211 TIGRFAM TIGR00547 lolA: outer membrane lipoprotein carrier protein LolA 13 207 5.6E-28 T 13-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 THITH_04950 405f3c241abc727ae56f9450a868871e 211 Hamap MF_00240 Outer-membrane lipoprotein carrier protein [lolA]. 13 211 28.792 T 13-10-2018 IPR018323 Outer membrane lipoprotein carrier protein LolA, Proteobacteria GO:0042597|GO:0042953|GO:0042954 THITH_04950 405f3c241abc727ae56f9450a868871e 211 SUPERFAMILY SSF89392 29 209 8.24E-43 T 13-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX THITH_04950 405f3c241abc727ae56f9450a868871e 211 Pfam PF03548 Outer membrane lipoprotein carrier protein LolA 39 201 1.2E-40 T 13-10-2018 IPR004564 Outer membrane lipoprotein carrier protein LolA-like THITH_04950 405f3c241abc727ae56f9450a868871e 211 Gene3D G3DSA:2.50.20.10 26 210 4.7E-46 T 13-10-2018 THITH_13815 06c59fe219cf00eeeaf42751fd8c4aaf 137 SUPERFAMILY SSF48695 10 101 4.06E-15 T 13-10-2018 IPR036280 Multiheme cytochrome superfamily THITH_13815 06c59fe219cf00eeeaf42751fd8c4aaf 137 Gene3D G3DSA:1.10.1130.10 1 127 2.9E-26 T 13-10-2018 THITH_13815 06c59fe219cf00eeeaf42751fd8c4aaf 137 Pfam PF13435 Cytochrome c554 and c-prime 3 44 9.7E-14 T 13-10-2018 IPR023155 Cytochrome c-552/4 THITH_06905 bf60253a04a2aa575b6df8e1ddbeb9dd 249 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 124 144 4.7E-51 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06905 bf60253a04a2aa575b6df8e1ddbeb9dd 249 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 48 65 4.7E-51 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06905 bf60253a04a2aa575b6df8e1ddbeb9dd 249 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 103 123 4.7E-51 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06905 bf60253a04a2aa575b6df8e1ddbeb9dd 249 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 65 85 4.7E-51 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06905 bf60253a04a2aa575b6df8e1ddbeb9dd 249 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 159 185 4.7E-51 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06905 bf60253a04a2aa575b6df8e1ddbeb9dd 249 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 207 231 4.7E-51 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_06905 bf60253a04a2aa575b6df8e1ddbeb9dd 249 Pfam PF01578 Cytochrome C assembly protein 32 187 3.6E-32 T 13-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 THITH_06905 bf60253a04a2aa575b6df8e1ddbeb9dd 249 TIGRFAM TIGR01191 ccmC: heme exporter protein CcmC 48 230 2.8E-74 T 13-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 THITH_10925 000f46f7409cae9ca6b750a5971441ec 282 SUPERFAMILY SSF53474 2 258 3.07E-34 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_10925 000f46f7409cae9ca6b750a5971441ec 282 ProSitePatterns PS01133 Uncharacterized protein family UPF0017 signature. 182 223 - T 13-10-2018 IPR000952 AB hydrolase 4, conserved site THITH_10925 000f46f7409cae9ca6b750a5971441ec 282 Pfam PF12146 Serine aminopeptidase, S33 19 229 2.7E-10 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 THITH_10925 000f46f7409cae9ca6b750a5971441ec 282 PIRSF PIRSF005211 1 282 6.0E-80 T 13-10-2018 IPR012020 AB hydrolase 4 family THITH_10665 8993f31cff407208efd4bd1c978346dc 129 TIGRFAM TIGR01841 phasin: phasin family protein 28 114 1.4E-8 T 13-10-2018 IPR010127 Phasin, subfamily 1 THITH_10665 8993f31cff407208efd4bd1c978346dc 129 Pfam PF09361 Phasin protein 9 105 2.4E-16 T 13-10-2018 IPR018968 Phasin THITH_17365 861f14dced89417452c1dfff1bed2634 860 Gene3D G3DSA:3.30.1490.20 5 176 7.5E-38 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 THITH_17365 861f14dced89417452c1dfff1bed2634 860 SUPERFAMILY SSF52009 751 855 2.75E-26 T 13-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 THITH_17365 861f14dced89417452c1dfff1bed2634 860 Pfam PF00391 PEP-utilising enzyme, mobile domain 784 853 5.3E-22 T 13-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 THITH_17365 861f14dced89417452c1dfff1bed2634 860 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 251 291 6.6E-7 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 THITH_17365 861f14dced89417452c1dfff1bed2634 860 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 17 234 1.0E-43 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 THITH_17365 861f14dced89417452c1dfff1bed2634 860 Gene3D G3DSA:3.50.30.10 755 858 2.6E-29 T 13-10-2018 THITH_17365 861f14dced89417452c1dfff1bed2634 860 Gene3D G3DSA:3.30.470.20 178 240 7.1E-10 T 13-10-2018 THITH_17365 861f14dced89417452c1dfff1bed2634 860 Gene3D G3DSA:3.30.470.20 247 306 2.9E-10 T 13-10-2018 THITH_17365 861f14dced89417452c1dfff1bed2634 860 SUPERFAMILY SSF56059 11 294 9.77E-60 T 13-10-2018 THITH_04115 ee1614d0853e25dddb55d9666a5e9b77 239 Pfam PF07386 Protein of unknown function (DUF1499) 99 234 7.4E-33 T 13-10-2018 IPR010865 Protein of unknown function DUF1499 THITH_13900 f18d1fac4f52c46896cbd19b72e70bfa 94 Gene3D G3DSA:2.60.120.10 1 92 1.1E-31 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_13900 f18d1fac4f52c46896cbd19b72e70bfa 94 SUPERFAMILY SSF51182 15 90 1.16E-16 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily THITH_13900 f18d1fac4f52c46896cbd19b72e70bfa 94 Pfam PF05899 Protein of unknown function (DUF861) 20 90 1.1E-26 T 13-10-2018 IPR008579 Domain of unknown function DUF861, cupin-3 KEGG: 00230+3.5.3.26|MetaCyc: PWY-5692|MetaCyc: PWY-5698 THITH_12050 13a434e6fa4db427027fe5b515177b59 224 Gene3D G3DSA:2.60.120.620 1 176 1.4E-38 T 13-10-2018 THITH_12050 13a434e6fa4db427027fe5b515177b59 224 Pfam PF13640 2OG-Fe(II) oxygenase superfamily 84 174 3.9E-15 T 13-10-2018 IPR005123 Oxoglutarate/iron-dependent dioxygenase GO:0016491|GO:0055114 THITH_12050 13a434e6fa4db427027fe5b515177b59 224 SUPERFAMILY SSF51197 54 167 7.97E-6 T 13-10-2018 THITH_12050 13a434e6fa4db427027fe5b515177b59 224 SMART SM00702 1 175 2.5E-14 T 13-10-2018 IPR006620 Prolyl 4-hydroxylase, alpha subunit GO:0005506|GO:0016705|GO:0031418|GO:0055114 THITH_12050 13a434e6fa4db427027fe5b515177b59 224 Hamap MF_00657 PKHD-type hydroxylase YbiX [ybiX]. 1 224 37.406 T 13-10-2018 IPR023550 PKHD-type hydroxylase GO:0016706|GO:0055114 THITH_14860 73b722f18ce9c13f6499795b067c9836 136 SUPERFAMILY SSF54427 5 122 6.08E-32 T 13-10-2018 IPR032710 NTF2-like domain superfamily THITH_14860 73b722f18ce9c13f6499795b067c9836 136 Pfam PF13474 SnoaL-like domain 11 120 3.0E-19 T 13-10-2018 IPR037401 SnoaL-like domain THITH_14860 73b722f18ce9c13f6499795b067c9836 136 Gene3D G3DSA:3.10.450.50 2 131 1.2E-38 T 13-10-2018 THITH_17415 b27b05e4b9e338471f885def28b58cb5 105 SUPERFAMILY SSF46626 14 100 9.15E-14 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_17415 b27b05e4b9e338471f885def28b58cb5 105 Gene3D G3DSA:1.10.760.10 26 103 4.3E-19 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_09650 13f3205f6c31cbb3e9d08952fafbd388 260 Gene3D G3DSA:1.20.120.1630 62 256 1.3E-10 T 13-10-2018 THITH_09650 13f3205f6c31cbb3e9d08952fafbd388 260 Pfam PF06966 Protein of unknown function (DUF1295) 24 250 1.9E-57 T 13-10-2018 IPR010721 Protein of unknown function DUF1295 THITH_03025 cf181df363902596bcaa3aaf29d1448f 552 Gene3D G3DSA:1.10.3820.10 53 204 1.9E-7 T 13-10-2018 IPR038266 NapC/NirT cytochrome c superfamily THITH_03025 cf181df363902596bcaa3aaf29d1448f 552 SUPERFAMILY SSF48695 35 425 6.64E-20 T 13-10-2018 IPR036280 Multiheme cytochrome superfamily THITH_14425 0806d3169019f77dfefaa6e8d7ef98f3 162 Pfam PF05258 Protein of unknown function (DUF721) 23 99 5.5E-8 T 13-10-2018 IPR007922 Protein of unknown function DUF721/UPF0232 THITH_06755 f85a5f29693dc689f620d5e646dd8470 453 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 131 142 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_06755 f85a5f29693dc689f620d5e646dd8470 453 SUPERFAMILY SSF54862 58 163 1.8E-14 T 13-10-2018 THITH_06755 f85a5f29693dc689f620d5e646dd8470 453 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 61 72 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_06755 f85a5f29693dc689f620d5e646dd8470 453 Pfam PF13183 4Fe-4S dicluster domain 58 145 9.9E-12 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_06755 f85a5f29693dc689f620d5e646dd8470 453 Gene3D G3DSA:1.10.1060.10 28 162 7.2E-6 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_06755 f85a5f29693dc689f620d5e646dd8470 453 Pfam PF02754 Cysteine-rich domain 337 425 4.3E-11 T 13-10-2018 IPR004017 Cysteine-rich domain THITH_08035 6f92b176f4793258332ac1a8c8e2afe8 258 Pfam PF01066 CDP-alcohol phosphatidyltransferase 82 151 6.3E-10 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THITH_08035 6f92b176f4793258332ac1a8c8e2afe8 258 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 129 151 - T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THITH_08035 6f92b176f4793258332ac1a8c8e2afe8 258 Gene3D G3DSA:1.20.120.1760 74 247 9.2E-9 T 13-10-2018 THITH_04885 5a9596ae16531d662803ddedf958a032 195 Pfam PF03625 Domain of unknown function DUF302 100 156 5.6E-11 T 13-10-2018 IPR005180 Domain of unknown function DUF302 THITH_04885 5a9596ae16531d662803ddedf958a032 195 SUPERFAMILY SSF103247 68 188 5.36E-17 T 13-10-2018 IPR035923 TT1751-like domain superfamily THITH_04885 5a9596ae16531d662803ddedf958a032 195 Gene3D G3DSA:3.30.310.70 62 189 3.3E-8 T 13-10-2018 IPR035923 TT1751-like domain superfamily THITH_08210 cf7f7a1e51ab04398562c4a32b5d5c65 225 Pfam PF02665 Nitrate reductase gamma subunit 5 225 8.3E-85 T 13-10-2018 IPR023234 NarG-like domain THITH_08210 cf7f7a1e51ab04398562c4a32b5d5c65 225 SUPERFAMILY SSF103501 1 224 1.31E-69 T 13-10-2018 IPR036197 NarG-like superfamily THITH_08210 cf7f7a1e51ab04398562c4a32b5d5c65 225 Gene3D G3DSA:1.20.950.20 1 217 2.5E-80 T 13-10-2018 THITH_08210 cf7f7a1e51ab04398562c4a32b5d5c65 225 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 1 225 1.3E-84 T 13-10-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 THITH_07875 cd63e1310354760d40e56bd75155d4b6 219 Pfam PF10972 Peptidoglycan-binding protein, CsiV 77 218 4.4E-17 T 13-10-2018 IPR021241 Peptidoglycan-binding protein, CsiV THITH_17380 85f3e41108f68f92ad111b7c4040f75f 170 Pfam PF03625 Domain of unknown function DUF302 73 133 2.6E-12 T 13-10-2018 IPR005180 Domain of unknown function DUF302 THITH_17380 85f3e41108f68f92ad111b7c4040f75f 170 Gene3D G3DSA:3.30.310.70 40 164 2.0E-13 T 13-10-2018 IPR035923 TT1751-like domain superfamily THITH_17380 85f3e41108f68f92ad111b7c4040f75f 170 SUPERFAMILY SSF103247 44 164 5.23E-24 T 13-10-2018 IPR035923 TT1751-like domain superfamily THITH_04095 068ee969b39f54066bef04069ca41d62 443 Gene3D G3DSA:3.50.50.60 7 279 2.8E-24 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_04095 068ee969b39f54066bef04069ca41d62 443 SUPERFAMILY SSF51905 5 415 7.45E-51 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_04095 068ee969b39f54066bef04069ca41d62 443 Gene3D G3DSA:1.10.3110.10 104 198 2.8E-24 T 13-10-2018 THITH_04095 068ee969b39f54066bef04069ca41d62 443 Gene3D G3DSA:3.90.660.20 35 224 2.8E-24 T 13-10-2018 THITH_04095 068ee969b39f54066bef04069ca41d62 443 Pfam PF13450 NAD(P)-binding Rossmann-like domain 8 77 3.1E-14 T 13-10-2018 THITH_13580 a9a7cc6d911f1441099b0f181404678d 215 Gene3D G3DSA:3.40.50.1110 44 213 2.1E-45 T 13-10-2018 IPR036514 SGNH hydrolase superfamily THITH_13580 a9a7cc6d911f1441099b0f181404678d 215 SUPERFAMILY SSF52266 45 210 4.12E-36 T 13-10-2018 THITH_13580 a9a7cc6d911f1441099b0f181404678d 215 ProSitePatterns PS01098 Lipolytic enzymes "G-D-S-L" family, serine active site. 46 56 - T 13-10-2018 IPR008265 Lipase, GDSL, active site GO:0006629|GO:0016298 Reactome: R-HSA-1482788|Reactome: R-HSA-975634 THITH_13580 a9a7cc6d911f1441099b0f181404678d 215 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 48 200 2.4E-21 T 13-10-2018 IPR013830 SGNH hydrolase-type esterase domain THITH_08060 5550b6e6c4987033a7b1aa69f351e469 338 Pfam PF02885 Glycosyl transferase family, helical bundle domain 23 77 4.2E-13 T 13-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 THITH_08060 5550b6e6c4987033a7b1aa69f351e469 338 Gene3D G3DSA:1.20.970.10 11 80 3.8E-21 T 13-10-2018 THITH_08060 5550b6e6c4987033a7b1aa69f351e469 338 SUPERFAMILY SSF52418 86 329 9.29E-57 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 THITH_08060 5550b6e6c4987033a7b1aa69f351e469 338 Gene3D G3DSA:3.40.1030.10 81 333 5.8E-60 T 13-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 THITH_08060 5550b6e6c4987033a7b1aa69f351e469 338 SUPERFAMILY SSF47648 20 78 1.01E-12 T 13-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 THITH_01380 f1d8dce05b82b65d1f4fa397dce3f710 954 Gene3D G3DSA:2.40.40.20 756 925 1.1E-26 T 13-10-2018 THITH_01380 f1d8dce05b82b65d1f4fa397dce3f710 954 Pfam PF00384 Molybdopterin oxidoreductase 64 616 2.6E-32 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_01380 f1d8dce05b82b65d1f4fa397dce3f710 954 Gene3D G3DSA:2.20.25.90 3 65 3.4E-18 T 13-10-2018 THITH_01380 f1d8dce05b82b65d1f4fa397dce3f710 954 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 9 60 6.6E-16 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_01380 f1d8dce05b82b65d1f4fa397dce3f710 954 SUPERFAMILY SSF50692 775 923 7.25E-33 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily THITH_01380 f1d8dce05b82b65d1f4fa397dce3f710 954 SUPERFAMILY SSF53706 7 711 1.83E-152 T 13-10-2018 THITH_01380 f1d8dce05b82b65d1f4fa397dce3f710 954 Gene3D G3DSA:3.40.50.740 475 641 7.8E-20 T 13-10-2018 THITH_01380 f1d8dce05b82b65d1f4fa397dce3f710 954 Gene3D G3DSA:3.40.50.740 66 155 6.3E-14 T 13-10-2018 THITH_01380 f1d8dce05b82b65d1f4fa397dce3f710 954 SMART SM00926 7 61 2.1E-18 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_01380 f1d8dce05b82b65d1f4fa397dce3f710 954 Pfam PF01568 Molydopterin dinucleotide binding domain 781 883 1.3E-13 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 THITH_14965 faadee2d580a664030e30e5e8ee0073b 343 SUPERFAMILY SSF52733 6 339 8.11E-114 T 13-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 THITH_14965 faadee2d580a664030e30e5e8ee0073b 343 Pfam PF02277 Phosphoribosyltransferase 7 339 1.3E-131 T 13-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 THITH_14965 faadee2d580a664030e30e5e8ee0073b 343 Gene3D G3DSA:1.10.1610.10 17 339 1.6E-126 T 13-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 THITH_14965 faadee2d580a664030e30e5e8ee0073b 343 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 5 341 36.228 T 13-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 THITH_14965 faadee2d580a664030e30e5e8ee0073b 343 Gene3D G3DSA:3.40.50.10210 49 322 1.6E-126 T 13-10-2018 THITH_14965 faadee2d580a664030e30e5e8ee0073b 343 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 7 339 1.5E-131 T 13-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 THITH_16220 90be67de4a5e59362ac85fa41ee79566 443 Pfam PF01966 HD domain 32 147 2.7E-6 T 13-10-2018 IPR006674 HD domain THITH_16220 90be67de4a5e59362ac85fa41ee79566 443 Pfam PF01966 HD domain 239 359 5.1E-18 T 13-10-2018 IPR006674 HD domain THITH_16220 90be67de4a5e59362ac85fa41ee79566 443 SUPERFAMILY SSF109604 12 183 8.9E-18 T 13-10-2018 THITH_16220 90be67de4a5e59362ac85fa41ee79566 443 Gene3D G3DSA:1.10.3210.10 219 412 5.4E-50 T 13-10-2018 THITH_16220 90be67de4a5e59362ac85fa41ee79566 443 Gene3D G3DSA:1.10.3210.10 6 190 4.0E-21 T 13-10-2018 THITH_16220 90be67de4a5e59362ac85fa41ee79566 443 SUPERFAMILY SSF109604 229 396 2.75E-31 T 13-10-2018 THITH_16220 90be67de4a5e59362ac85fa41ee79566 443 SMART SM00471 25 154 0.043 T 13-10-2018 IPR003607 HD/PDEase domain THITH_16220 90be67de4a5e59362ac85fa41ee79566 443 SMART SM00471 234 369 1.3E-13 T 13-10-2018 IPR003607 HD/PDEase domain THITH_14315 ec9b11df3357a4287954d8ec7723207b 125 Gene3D G3DSA:2.40.50.140 1 125 7.3E-62 T 13-10-2018 THITH_14315 ec9b11df3357a4287954d8ec7723207b 125 PIRSF PIRSF002133 1 124 4.2E-53 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14315 ec9b11df3357a4287954d8ec7723207b 125 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 38.86 T 13-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14315 ec9b11df3357a4287954d8ec7723207b 125 Pfam PF00164 Ribosomal protein S12/S23 12 123 9.2E-42 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14315 ec9b11df3357a4287954d8ec7723207b 125 SUPERFAMILY SSF50249 3 124 2.14E-50 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_14315 ec9b11df3357a4287954d8ec7723207b 125 PRINTS PR01034 Ribosomal protein S12 signature 42 57 6.6E-58 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14315 ec9b11df3357a4287954d8ec7723207b 125 PRINTS PR01034 Ribosomal protein S12 signature 94 110 6.6E-58 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14315 ec9b11df3357a4287954d8ec7723207b 125 PRINTS PR01034 Ribosomal protein S12 signature 27 42 6.6E-58 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14315 ec9b11df3357a4287954d8ec7723207b 125 PRINTS PR01034 Ribosomal protein S12 signature 77 94 6.6E-58 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14315 ec9b11df3357a4287954d8ec7723207b 125 PRINTS PR01034 Ribosomal protein S12 signature 58 77 6.6E-58 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14315 ec9b11df3357a4287954d8ec7723207b 125 PRINTS PR01034 Ribosomal protein S12 signature 110 122 6.6E-58 T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14315 ec9b11df3357a4287954d8ec7723207b 125 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 13-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_14315 ec9b11df3357a4287954d8ec7723207b 125 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 124 4.4E-68 T 13-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_03595 0b808032ac9310626a4375f573d06b3b 145 Pfam PF01597 Glycine cleavage H-protein 15 129 2.0E-36 T 13-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate THITH_03595 0b808032ac9310626a4375f573d06b3b 145 SUPERFAMILY SSF51230 14 128 5.05E-30 T 13-10-2018 IPR011053 Single hybrid motif THITH_03595 0b808032ac9310626a4375f573d06b3b 145 Gene3D G3DSA:2.40.50.100 7 135 2.9E-36 T 13-10-2018 THITH_03595 0b808032ac9310626a4375f573d06b3b 145 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 10 138 30.888 T 13-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 THITH_16755 294b2adb0459c955e6550c5988e94a9a 430 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 4 427 3.3E-197 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THITH_16755 294b2adb0459c955e6550c5988e94a9a 430 PRINTS PR00758 Arsenical pump membrane protein signature 398 422 3.1E-106 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THITH_16755 294b2adb0459c955e6550c5988e94a9a 430 PRINTS PR00758 Arsenical pump membrane protein signature 178 201 3.1E-106 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THITH_16755 294b2adb0459c955e6550c5988e94a9a 430 PRINTS PR00758 Arsenical pump membrane protein signature 145 169 3.1E-106 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THITH_16755 294b2adb0459c955e6550c5988e94a9a 430 PRINTS PR00758 Arsenical pump membrane protein signature 218 243 3.1E-106 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THITH_16755 294b2adb0459c955e6550c5988e94a9a 430 PRINTS PR00758 Arsenical pump membrane protein signature 324 346 3.1E-106 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THITH_16755 294b2adb0459c955e6550c5988e94a9a 430 PRINTS PR00758 Arsenical pump membrane protein signature 102 126 3.1E-106 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THITH_16755 294b2adb0459c955e6550c5988e94a9a 430 PRINTS PR00758 Arsenical pump membrane protein signature 279 303 3.1E-106 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THITH_16755 294b2adb0459c955e6550c5988e94a9a 430 PRINTS PR00758 Arsenical pump membrane protein signature 365 390 3.1E-106 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THITH_16755 294b2adb0459c955e6550c5988e94a9a 430 Pfam PF02040 Arsenical pump membrane protein 5 426 1.0E-154 T 13-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 THITH_04260 4e687119823c7213374ae6a431ed2cbb 431 Gene3D G3DSA:3.50.50.60 2 405 2.1E-99 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_04260 4e687119823c7213374ae6a431ed2cbb 431 Pfam PF01494 FAD binding domain 5 337 1.2E-16 T 13-10-2018 IPR002938 FAD-binding domain GO:0071949 THITH_04260 4e687119823c7213374ae6a431ed2cbb 431 SUPERFAMILY SSF51905 5 363 2.97E-44 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_04260 4e687119823c7213374ae6a431ed2cbb 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 152 167 2.5E-9 T 13-10-2018 THITH_04260 4e687119823c7213374ae6a431ed2cbb 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 2.5E-9 T 13-10-2018 THITH_04260 4e687119823c7213374ae6a431ed2cbb 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 312 2.5E-9 T 13-10-2018 THITH_02335 a8b9bdaf9f30e857595396988ae29ef4 193 SUPERFAMILY SSF52833 5 191 5.69E-50 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_02335 a8b9bdaf9f30e857595396988ae29ef4 193 Pfam PF00578 AhpC/TSA family 12 136 5.0E-17 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THITH_02335 a8b9bdaf9f30e857595396988ae29ef4 193 Gene3D G3DSA:3.40.30.10 3 193 2.1E-55 T 13-10-2018 THITH_01050 bc5afbb069f4642859221d7601fdeca9 90 SUPERFAMILY SSF143011 1 88 3.92E-25 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_01050 bc5afbb069f4642859221d7601fdeca9 90 TIGRFAM TIGR00053 TIGR00053: addiction module toxin component, YafQ family 3 88 1.4E-26 T 13-10-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin THITH_01050 bc5afbb069f4642859221d7601fdeca9 90 PIRSF PIRSF006156 1 90 2.2E-24 T 13-10-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin THITH_01050 bc5afbb069f4642859221d7601fdeca9 90 Pfam PF15738 Bacterial toxin of type II toxin-antitoxin system, YafQ 5 89 3.8E-31 T 13-10-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin THITH_01050 bc5afbb069f4642859221d7601fdeca9 90 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 7 88 9.0E-26 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THITH_01050 bc5afbb069f4642859221d7601fdeca9 90 Gene3D G3DSA:3.30.2310.20 1 90 1.1E-30 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_03320 24ad7ba9c1deb95f47697129b95c13af 423 SUPERFAMILY SSF69318 34 406 1.37E-20 T 13-10-2018 THITH_01875 1f14142588fbca1179af2bc8aebb73c9 467 SUPERFAMILY SSF140931 205 374 5.75E-17 T 13-10-2018 IPR036597 Fido-like domain superfamily THITH_01875 1f14142588fbca1179af2bc8aebb73c9 467 Gene3D G3DSA:1.10.3290.10 151 380 5.3E-33 T 13-10-2018 IPR036597 Fido-like domain superfamily THITH_01875 1f14142588fbca1179af2bc8aebb73c9 467 Pfam PF02661 Fic/DOC family 231 321 1.5E-7 T 13-10-2018 IPR003812 Fido domain THITH_01470 ae315789602b107af1aba2cd0290010a 288 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 288 2.9E-84 T 13-10-2018 IPR005229 Conserved hypothetical protein CHP00255 THITH_01470 ae315789602b107af1aba2cd0290010a 288 Pfam PF03755 YicC-like family, N-terminal region 4 154 3.0E-39 T 13-10-2018 IPR013527 YicC-like, N-terminal THITH_01470 ae315789602b107af1aba2cd0290010a 288 Pfam PF08340 Domain of unknown function (DUF1732) 204 288 3.7E-35 T 13-10-2018 IPR013551 Domain of unknown function DUF1732 THITH_07750 4b31af5ee22b00e11c87b98d5ec6a721 257 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 18 254 1.6E-82 T 13-10-2018 THITH_07750 4b31af5ee22b00e11c87b98d5ec6a721 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 4.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_07750 4b31af5ee22b00e11c87b98d5ec6a721 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 4.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_07750 4b31af5ee22b00e11c87b98d5ec6a721 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 4.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_07750 4b31af5ee22b00e11c87b98d5ec6a721 257 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 4.0E-12 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_07750 4b31af5ee22b00e11c87b98d5ec6a721 257 SUPERFAMILY SSF51735 8 255 3.27E-68 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_07750 4b31af5ee22b00e11c87b98d5ec6a721 257 PIRSF PIRSF000094 5 257 6.3E-89 T 13-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 THITH_07750 4b31af5ee22b00e11c87b98d5ec6a721 257 Gene3D G3DSA:3.40.50.720 2 256 2.0E-60 T 13-10-2018 THITH_16045 b04742d8989941970fdc6c1a07dc0746 237 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 1 230 1.2E-68 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 THITH_16045 b04742d8989941970fdc6c1a07dc0746 237 Pfam PF01168 Alanine racemase, N-terminal domain 20 230 1.8E-28 T 13-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 THITH_16045 b04742d8989941970fdc6c1a07dc0746 237 SUPERFAMILY SSF51419 4 228 2.09E-77 T 13-10-2018 IPR029066 PLP-binding barrel THITH_16045 b04742d8989941970fdc6c1a07dc0746 237 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 6 229 31.86 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 THITH_16045 b04742d8989941970fdc6c1a07dc0746 237 PIRSF PIRSF004848 1 236 1.5E-71 T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 THITH_16045 b04742d8989941970fdc6c1a07dc0746 237 Gene3D G3DSA:3.20.20.10 1 236 7.6E-85 T 13-10-2018 IPR029066 PLP-binding barrel THITH_16045 b04742d8989941970fdc6c1a07dc0746 237 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 80 94 - T 13-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 THITH_09210 2fa517f16cab9a354323d760a94f448c 514 TIGRFAM TIGR02677 TIGR02677: TIGR02677 family protein 5 509 5.9E-152 T 13-10-2018 IPR013493 Conserved hypothetical protein CHP02677 THITH_09210 2fa517f16cab9a354323d760a94f448c 514 Pfam PF09660 Protein of unknown function (DUF2397) 6 504 2.4E-157 T 13-10-2018 IPR013493 Conserved hypothetical protein CHP02677 THITH_06810 bda5212b885d324b29d797730612b1e1 182 SUPERFAMILY SSF54197 9 153 3.54E-25 T 13-10-2018 IPR036265 HIT-like superfamily THITH_06810 bda5212b885d324b29d797730612b1e1 182 Pfam PF01230 HIT domain 23 145 1.6E-13 T 13-10-2018 IPR001310 Histidine triad (HIT) protein THITH_10450 9c1d1d758a0c26a4e88d2ebb0227b9f2 244 Gene3D G3DSA:3.40.1160.10 2 242 7.4E-77 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THITH_10450 9c1d1d758a0c26a4e88d2ebb0227b9f2 244 Pfam PF00696 Amino acid kinase family 11 219 5.3E-27 T 13-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 THITH_10450 9c1d1d758a0c26a4e88d2ebb0227b9f2 244 Hamap MF_01220_B Uridylate kinase [pyrH]. 7 240 44.816 T 13-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 THITH_10450 9c1d1d758a0c26a4e88d2ebb0227b9f2 244 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 9 240 1.5E-96 T 13-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 THITH_10450 9c1d1d758a0c26a4e88d2ebb0227b9f2 244 SUPERFAMILY SSF53633 7 239 1.7E-70 T 13-10-2018 IPR036393 Acetylglutamate kinase-like superfamily THITH_10450 9c1d1d758a0c26a4e88d2ebb0227b9f2 244 PIRSF PIRSF005650 5 244 2.9E-90 T 13-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 THITH_08820 c680eac49f46272d0714634b66f06b0b 392 SMART SM00558 91 228 0.0096 T 13-10-2018 IPR003347 JmjC domain THITH_08820 c680eac49f46272d0714634b66f06b0b 392 Pfam PF08007 Cupin superfamily protein 12 292 1.1E-76 T 13-10-2018 IPR003347 JmjC domain THITH_08820 c680eac49f46272d0714634b66f06b0b 392 SUPERFAMILY SSF51197 6 287 1.14E-64 T 13-10-2018 THITH_08820 c680eac49f46272d0714634b66f06b0b 392 Gene3D G3DSA:1.10.10.2510 226 382 4.9E-11 T 13-10-2018 THITH_08820 c680eac49f46272d0714634b66f06b0b 392 Gene3D G3DSA:2.60.120.650 1 213 1.5E-84 T 13-10-2018 THITH_10345 e7fbcb5d0faa88602687030289df6990 190 Gene3D G3DSA:3.30.70.3270 55 183 1.9E-31 T 13-10-2018 THITH_10345 e7fbcb5d0faa88602687030289df6990 190 SUPERFAMILY SSF54862 78 147 5.11E-21 T 13-10-2018 THITH_10345 e7fbcb5d0faa88602687030289df6990 190 Pfam PF12838 4Fe-4S dicluster domain 82 139 3.6E-11 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_10345 e7fbcb5d0faa88602687030289df6990 190 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 125 136 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_10345 e7fbcb5d0faa88602687030289df6990 190 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 19 186 23.88 T 13-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_09940 ca3b024f37ab7ce5343893ac6caca628 187 Pfam PF01292 Prokaryotic cytochrome b561 3 178 6.7E-25 T 13-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 THITH_09940 ca3b024f37ab7ce5343893ac6caca628 187 SUPERFAMILY SSF81342 2 179 2.75E-27 T 13-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 THITH_15260 e4b770f4db02923a891c87d1290518e4 320 SUPERFAMILY SSF46689 219 318 1.36E-12 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_15260 e4b770f4db02923a891c87d1290518e4 320 Gene3D G3DSA:1.10.8.60 177 244 1.1E-19 T 13-10-2018 THITH_15260 e4b770f4db02923a891c87d1290518e4 320 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 219 228 - T 13-10-2018 IPR025944 Sigma-54 interaction domain, conserved site THITH_15260 e4b770f4db02923a891c87d1290518e4 320 SMART SM00382 26 173 1.1E-10 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_15260 e4b770f4db02923a891c87d1290518e4 320 Pfam PF02954 Bacterial regulatory protein, Fis family 277 316 1.9E-13 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_15260 e4b770f4db02923a891c87d1290518e4 320 Pfam PF00158 Sigma-54 interaction domain 6 172 2.0E-63 T 13-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 THITH_15260 e4b770f4db02923a891c87d1290518e4 320 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 30 43 - T 13-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 THITH_15260 e4b770f4db02923a891c87d1290518e4 320 Gene3D G3DSA:1.10.10.60 268 319 1.8E-11 T 13-10-2018 THITH_15260 e4b770f4db02923a891c87d1290518e4 320 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 282 299 1.0E-12 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_15260 e4b770f4db02923a891c87d1290518e4 320 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 299 319 1.0E-12 T 13-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 THITH_15260 e4b770f4db02923a891c87d1290518e4 320 SUPERFAMILY SSF52540 6 247 1.22E-66 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_15260 e4b770f4db02923a891c87d1290518e4 320 Gene3D G3DSA:3.40.50.300 1 176 1.5E-60 T 13-10-2018 THITH_15260 e4b770f4db02923a891c87d1290518e4 320 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 92 107 - T 13-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 THITH_14595 5a63e9a4011e38003631967df9374dd9 419 Gene3D G3DSA:3.65.10.10 6 414 7.1E-170 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 THITH_14595 5a63e9a4011e38003631967df9374dd9 419 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 407 6.6E-113 T 13-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 THITH_14595 5a63e9a4011e38003631967df9374dd9 419 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 416 1.2E-178 T 13-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_14595 5a63e9a4011e38003631967df9374dd9 419 SUPERFAMILY SSF55205 1 417 9.81E-141 T 13-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 THITH_14595 5a63e9a4011e38003631967df9374dd9 419 Gene3D G3DSA:3.65.10.10 21 229 7.1E-170 T 13-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 THITH_14595 5a63e9a4011e38003631967df9374dd9 419 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 44.714 T 13-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 THITH_08770 fed9a60c8d342c9e8272e72a461e8bee 427 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 3 419 3.6E-217 T 13-10-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 THITH_08770 fed9a60c8d342c9e8272e72a461e8bee 427 Gene3D G3DSA:3.40.718.10 1 419 4.8E-179 T 13-10-2018 THITH_08770 fed9a60c8d342c9e8272e72a461e8bee 427 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 31 414 2.2E-111 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 THITH_08770 fed9a60c8d342c9e8272e72a461e8bee 427 SMART SM01329 30 414 7.5E-176 T 13-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 THITH_08770 fed9a60c8d342c9e8272e72a461e8bee 427 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 305 324 - T 13-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 THITH_08770 fed9a60c8d342c9e8272e72a461e8bee 427 SUPERFAMILY SSF53659 8 418 5.95E-144 T 13-10-2018 THITH_16315 5f5cbd8f5226395ef2c2e84a730751e1 236 Pfam PF04376 Arginine-tRNA-protein transferase, N terminus 15 84 4.5E-15 T 13-10-2018 IPR007471 N-end aminoacyl transferase, N-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 THITH_16315 5f5cbd8f5226395ef2c2e84a730751e1 236 Pfam PF04377 Arginine-tRNA-protein transferase, C terminus 104 223 3.6E-33 T 13-10-2018 IPR007472 N-end rule aminoacyl transferase, C-terminal GO:0004057|GO:0016598 MetaCyc: PWY-7802 THITH_16315 5f5cbd8f5226395ef2c2e84a730751e1 236 SUPERFAMILY SSF55729 78 234 3.54E-25 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_16315 5f5cbd8f5226395ef2c2e84a730751e1 236 PIRSF PIRSF037208 1 235 2.1E-78 T 13-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 THITH_16315 5f5cbd8f5226395ef2c2e84a730751e1 236 Hamap MF_00689 Aspartate/glutamate leucyltransferase [bpt]. 4 231 38.24 T 13-10-2018 IPR017138 Aspartate/glutamate leucyltransferase GO:0008914|GO:0071596 MetaCyc: PWY-7802 THITH_02525 2f37182f0b60e220b4f43f42b91f22bb 231 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 3 204 7.7E-38 T 13-10-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like THITH_02525 2f37182f0b60e220b4f43f42b91f22bb 231 Pfam PF12710 haloacid dehalogenase-like hydrolase 4 191 1.3E-39 T 13-10-2018 THITH_02525 2f37182f0b60e220b4f43f42b91f22bb 231 SUPERFAMILY SSF56784 1 212 3.53E-34 T 13-10-2018 IPR036412 HAD-like superfamily THITH_02525 2f37182f0b60e220b4f43f42b91f22bb 231 Gene3D G3DSA:3.40.50.1000 3 215 1.3E-75 T 13-10-2018 IPR023214 HAD superfamily THITH_02525 2f37182f0b60e220b4f43f42b91f22bb 231 Gene3D G3DSA:1.20.1440.100 15 88 1.3E-75 T 13-10-2018 THITH_02525 2f37182f0b60e220b4f43f42b91f22bb 231 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 3 192 4.6E-25 T 13-10-2018 THITH_05930 1cbb8b41a4fbfcafb0aefd4c6ba932e8 104 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 12 92 1.5E-20 T 13-10-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system THITH_05930 1cbb8b41a4fbfcafb0aefd4c6ba932e8 104 Gene3D G3DSA:3.10.450.530 2 95 1.0E-7 T 13-10-2018 IPR038573 Ribonuclease toxin BrnT superfamily THITH_10670 75fa77f6491419ea417cb1f640ac2e10 248 TIGRFAM TIGR01829 AcAcCoA_reduct: acetoacetyl-CoA reductase 4 246 1.6E-116 T 13-10-2018 IPR011283 Acetoacetyl-CoA reductase GO:0005737|GO:0018454|GO:0042619|GO:0055114 KEGG: 00630+1.1.1.36|KEGG: 00650+1.1.1.36|MetaCyc: PWY-5676|MetaCyc: PWY-5741|MetaCyc: PWY-7216|MetaCyc: PWY-7948 THITH_10670 75fa77f6491419ea417cb1f640ac2e10 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 4.7E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_10670 75fa77f6491419ea417cb1f640ac2e10 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 4.7E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_10670 75fa77f6491419ea417cb1f640ac2e10 248 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 4.7E-14 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_10670 75fa77f6491419ea417cb1f640ac2e10 248 Pfam PF00106 short chain dehydrogenase 5 198 1.7E-61 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_10670 75fa77f6491419ea417cb1f640ac2e10 248 SUPERFAMILY SSF51735 4 246 3.88E-78 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_10670 75fa77f6491419ea417cb1f640ac2e10 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 1.3E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_10670 75fa77f6491419ea417cb1f640ac2e10 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.3E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_10670 75fa77f6491419ea417cb1f640ac2e10 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 1.3E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_10670 75fa77f6491419ea417cb1f640ac2e10 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 1.3E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_10670 75fa77f6491419ea417cb1f640ac2e10 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 1.3E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_10670 75fa77f6491419ea417cb1f640ac2e10 248 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 1.3E-41 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_10670 75fa77f6491419ea417cb1f640ac2e10 248 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 190 3.3E-6 T 13-10-2018 THITH_10670 75fa77f6491419ea417cb1f640ac2e10 248 Gene3D G3DSA:3.40.50.720 1 246 2.1E-81 T 13-10-2018 THITH_10670 75fa77f6491419ea417cb1f640ac2e10 248 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THITH_17080 db3ef0580da9480f5c517839daf9228c 142 Pfam PF00581 Rhodanese-like domain 43 135 6.7E-16 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_17080 db3ef0580da9480f5c517839daf9228c 142 SUPERFAMILY SSF52821 21 141 9.17E-34 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_17080 db3ef0580da9480f5c517839daf9228c 142 SMART SM00450 41 138 1.4E-22 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_17080 db3ef0580da9480f5c517839daf9228c 142 Gene3D G3DSA:3.40.250.10 23 142 1.9E-29 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_03785 3570e87862893db73c9f6c6c354fb764 379 Pfam PF00563 EAL domain 102 324 6.0E-35 T 13-10-2018 IPR001633 EAL domain THITH_03785 3570e87862893db73c9f6c6c354fb764 379 Gene3D G3DSA:3.20.20.450 99 338 4.2E-36 T 13-10-2018 IPR035919 EAL domain superfamily THITH_03785 3570e87862893db73c9f6c6c354fb764 379 SMART SM00052 82 331 6.1E-9 T 13-10-2018 IPR001633 EAL domain THITH_03785 3570e87862893db73c9f6c6c354fb764 379 SUPERFAMILY SSF141868 104 333 3.01E-34 T 13-10-2018 IPR035919 EAL domain superfamily THITH_08040 89b6eee4246ab926d54d296b5bc72b77 122 Pfam PF00581 Rhodanese-like domain 21 111 1.9E-11 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_08040 89b6eee4246ab926d54d296b5bc72b77 122 Gene3D G3DSA:3.40.250.10 19 121 3.9E-21 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_08040 89b6eee4246ab926d54d296b5bc72b77 122 SMART SM00450 19 116 2.0E-19 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_08040 89b6eee4246ab926d54d296b5bc72b77 122 SUPERFAMILY SSF52821 10 120 3.54E-26 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_16780 d2257ff89d06cca7cba3e928861ad53c 139 Gene3D G3DSA:3.40.50.1010 1 134 3.4E-36 T 13-10-2018 THITH_16780 d2257ff89d06cca7cba3e928861ad53c 139 SUPERFAMILY SSF88723 2 133 5.61E-30 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_16780 d2257ff89d06cca7cba3e928861ad53c 139 Pfam PF01850 PIN domain 3 126 1.7E-14 T 13-10-2018 IPR002716 PIN domain THITH_16780 d2257ff89d06cca7cba3e928861ad53c 139 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 132 13.116 T 13-10-2018 IPR022907 VapC family GO:0004540 THITH_12595 f3f85389301f6ce879e48fbc5484f8db 887 PIRSF PIRSF035905 4 884 2.1E-88 T 13-10-2018 IPR014600 Uncharacterised conserved protein UCP035905, membrane protein THITH_12595 f3f85389301f6ce879e48fbc5484f8db 887 Pfam PF10101 Predicted membrane protein (DUF2339) 122 874 2.5E-133 T 13-10-2018 IPR019286 Protein of unknown function DUF2339, transmembrane THITH_12175 81ab866c76cfb1d01eda26aeb0279a10 176 SUPERFAMILY SSF89069 9 75 5.89E-15 T 13-10-2018 IPR036147 Anti sigma-E protein RseA, N-terminal domain superfamily GO:0016989 THITH_12175 81ab866c76cfb1d01eda26aeb0279a10 176 Pfam PF03872 Anti sigma-E protein RseA, N-terminal domain 9 76 1.5E-16 T 13-10-2018 IPR005572 Anti sigma-E protein RseA, N-terminal GO:0016989 THITH_12175 81ab866c76cfb1d01eda26aeb0279a10 176 Gene3D G3DSA:1.10.10.880 8 75 2.5E-17 T 13-10-2018 IPR036147 Anti sigma-E protein RseA, N-terminal domain superfamily GO:0016989 THITH_00485 7041f3fe6208e7810dd821fb7b6373b1 101 Gene3D G3DSA:2.60.40.10 1 101 3.2E-34 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_00485 7041f3fe6208e7810dd821fb7b6373b1 101 Pfam PF08770 Sulphur oxidation protein SoxZ 6 98 6.7E-38 T 13-10-2018 IPR014880 Sulphur oxidation protein SoxZ THITH_00485 7041f3fe6208e7810dd821fb7b6373b1 101 TIGRFAM TIGR04490 SoxZ_true: thiosulfate oxidation carrier complex protein SoxZ 5 100 1.2E-39 T 13-10-2018 IPR030995 Thiosulfate oxidation carrier complex protein SoxZ THITH_00485 7041f3fe6208e7810dd821fb7b6373b1 101 SUPERFAMILY SSF81296 1 100 3.92E-31 T 13-10-2018 IPR014756 Immunoglobulin E-set THITH_00475 09d3fe2b39d77cd9a37f280f1867fc0b 197 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 63 76 - T 13-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 THITH_00475 09d3fe2b39d77cd9a37f280f1867fc0b 197 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 33 176 2.3E-65 T 13-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 THITH_00475 09d3fe2b39d77cd9a37f280f1867fc0b 197 Gene3D G3DSA:3.30.230.40 92 197 1.1E-39 T 13-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 THITH_00475 09d3fe2b39d77cd9a37f280f1867fc0b 197 SUPERFAMILY SSF54211 89 181 4.55E-35 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_00475 09d3fe2b39d77cd9a37f280f1867fc0b 197 Gene3D G3DSA:3.30.230.40 1 91 3.6E-36 T 13-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 THITH_00475 09d3fe2b39d77cd9a37f280f1867fc0b 197 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 4 197 42.515 T 13-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 THITH_00475 09d3fe2b39d77cd9a37f280f1867fc0b 197 SUPERFAMILY SSF54211 4 88 5.31E-32 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_00475 09d3fe2b39d77cd9a37f280f1867fc0b 197 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 158 170 - T 13-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 THITH_17160 2f22b7804e2a8c32085cee7c9f8fdf45 205 PRINTS PR00605 Class IC cytochrome C signature 35 46 2.1E-5 T 13-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 THITH_17160 2f22b7804e2a8c32085cee7c9f8fdf45 205 PRINTS PR00605 Class IC cytochrome C signature 177 199 2.1E-5 T 13-10-2018 IPR008168 Cytochrome c, class IC GO:0005506|GO:0009055 THITH_17160 2f22b7804e2a8c32085cee7c9f8fdf45 205 SUPERFAMILY SSF46626 131 202 4.01E-21 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_17160 2f22b7804e2a8c32085cee7c9f8fdf45 205 PIRSF PIRSF000005 2 204 9.5E-61 T 13-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 THITH_17160 2f22b7804e2a8c32085cee7c9f8fdf45 205 Gene3D G3DSA:1.10.760.10 106 203 2.1E-29 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_17160 2f22b7804e2a8c32085cee7c9f8fdf45 205 SUPERFAMILY SSF46626 14 101 3.94E-22 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_17160 2f22b7804e2a8c32085cee7c9f8fdf45 205 Gene3D G3DSA:1.10.760.10 28 103 6.7E-26 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_17160 2f22b7804e2a8c32085cee7c9f8fdf45 205 Pfam PF00034 Cytochrome c 28 98 1.7E-7 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_17160 2f22b7804e2a8c32085cee7c9f8fdf45 205 Pfam PF00034 Cytochrome c 115 201 4.3E-10 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_11810 c962678cee3027f866e804b1c6568710 318 Pfam PF12849 PBP superfamily domain 38 289 4.4E-31 T 13-10-2018 IPR024370 PBP domain THITH_11810 c962678cee3027f866e804b1c6568710 318 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 3 302 3.9E-75 T 13-10-2018 IPR011862 Phosphate binding protein GO:0042301 THITH_11810 c962678cee3027f866e804b1c6568710 318 Gene3D G3DSA:3.40.190.10 124 261 7.4E-97 T 13-10-2018 THITH_11810 c962678cee3027f866e804b1c6568710 318 SUPERFAMILY SSF53850 37 313 1.15E-65 T 13-10-2018 THITH_11810 c962678cee3027f866e804b1c6568710 318 Gene3D G3DSA:3.40.190.10 39 305 7.4E-97 T 13-10-2018 THITH_10395 99253e0a23027e396988746028158e30 220 SUPERFAMILY SSF52833 16 87 2.33E-6 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_10395 99253e0a23027e396988746028158e30 220 Pfam PF13646 HEAT repeats 167 215 2.9E-7 T 13-10-2018 THITH_10395 99253e0a23027e396988746028158e30 220 Gene3D G3DSA:1.25.10.10 102 220 1.5E-10 T 13-10-2018 IPR011989 Armadillo-like helical THITH_10395 99253e0a23027e396988746028158e30 220 SUPERFAMILY SSF48371 120 217 2.73E-10 T 13-10-2018 IPR016024 Armadillo-type fold THITH_10395 99253e0a23027e396988746028158e30 220 Gene3D G3DSA:3.40.30.10 10 89 9.7E-6 T 13-10-2018 THITH_09200 99e3eee3d4cfd6fc13e4215b959eca62 102 Gene3D G3DSA:1.10.1660.10 14 102 1.3E-19 T 13-10-2018 THITH_09200 99e3eee3d4cfd6fc13e4215b959eca62 102 Pfam PF13591 MerR HTH family regulatory protein 17 98 2.7E-10 T 13-10-2018 THITH_13075 9bd568ae19f87086a0d071dd1ce4877b 141 SMART SM00450 10 124 9.7E-13 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_13075 9bd568ae19f87086a0d071dd1ce4877b 141 Pfam PF00581 Rhodanese-like domain 15 116 1.1E-9 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_13075 9bd568ae19f87086a0d071dd1ce4877b 141 SUPERFAMILY SSF52821 4 140 3.01E-20 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_13075 9bd568ae19f87086a0d071dd1ce4877b 141 Gene3D G3DSA:3.40.250.10 5 141 3.0E-30 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_02455 9f32f1c118edeca974d8f3a56c72ca0a 170 SMART SM00731 11 162 1.1E-6 T 13-10-2018 IPR006640 SprT-like THITH_02455 9f32f1c118edeca974d8f3a56c72ca0a 170 Pfam PF10263 SprT-like family 31 108 5.3E-8 T 13-10-2018 IPR006640 SprT-like THITH_11895 bb3a236aa4b0a1f49044d6fc875e2cb9 390 Gene3D G3DSA:2.130.10.10 21 387 4.8E-83 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 THITH_11895 bb3a236aa4b0a1f49044d6fc875e2cb9 390 Pfam PF13360 PQQ-like domain 78 312 6.5E-42 T 13-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat THITH_11895 bb3a236aa4b0a1f49044d6fc875e2cb9 390 TIGRFAM TIGR03300 assembly_YfgL: outer membrane assembly lipoprotein YfgL 7 383 9.0E-115 T 13-10-2018 IPR017687 Outer membrane protein assembly factor BamB THITH_11895 bb3a236aa4b0a1f49044d6fc875e2cb9 390 SUPERFAMILY SSF50998 26 374 3.92E-66 T 13-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily THITH_11895 bb3a236aa4b0a1f49044d6fc875e2cb9 390 Hamap MF_00923 Outer membrane protein assembly factor BamB [bamB]. 3 385 33.914 T 13-10-2018 IPR017687 Outer membrane protein assembly factor BamB THITH_11895 bb3a236aa4b0a1f49044d6fc875e2cb9 390 SMART SM00564 105 137 0.15 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THITH_11895 bb3a236aa4b0a1f49044d6fc875e2cb9 390 SMART SM00564 323 354 0.0064 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THITH_11895 bb3a236aa4b0a1f49044d6fc875e2cb9 390 SMART SM00564 281 313 14.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THITH_11895 bb3a236aa4b0a1f49044d6fc875e2cb9 390 SMART SM00564 146 177 0.0071 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THITH_11895 bb3a236aa4b0a1f49044d6fc875e2cb9 390 SMART SM00564 190 222 430.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THITH_11895 bb3a236aa4b0a1f49044d6fc875e2cb9 390 SMART SM00564 241 273 36.0 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THITH_11895 bb3a236aa4b0a1f49044d6fc875e2cb9 390 SMART SM00564 64 96 0.11 T 13-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat THITH_16280 a4c1fae254a0bf54f327381a8ab1f9b8 284 Gene3D G3DSA:3.40.50.1820 41 280 2.4E-32 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_16280 a4c1fae254a0bf54f327381a8ab1f9b8 284 SUPERFAMILY SSF53474 47 280 5.0E-28 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_16280 a4c1fae254a0bf54f327381a8ab1f9b8 284 Pfam PF01738 Dienelactone hydrolase family 61 278 2.9E-14 T 13-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 THITH_14490 40fa9b2cf1275fe78e4a5832ba56fe50 500 Pfam PF01225 Mur ligase family, catalytic domain 25 94 3.7E-6 T 13-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 THITH_14490 40fa9b2cf1275fe78e4a5832ba56fe50 500 Gene3D G3DSA:3.40.1390.10 10 101 2.7E-15 T 13-10-2018 THITH_14490 40fa9b2cf1275fe78e4a5832ba56fe50 500 Gene3D G3DSA:3.90.190.20 343 495 1.4E-55 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THITH_14490 40fa9b2cf1275fe78e4a5832ba56fe50 500 SUPERFAMILY SSF53623 106 339 2.63E-65 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THITH_14490 40fa9b2cf1275fe78e4a5832ba56fe50 500 SUPERFAMILY SSF53244 340 490 1.05E-50 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THITH_14490 40fa9b2cf1275fe78e4a5832ba56fe50 500 SUPERFAMILY SSF63418 19 100 5.89E-15 T 13-10-2018 IPR035911 MurE/MurF, N-terminal THITH_14490 40fa9b2cf1275fe78e4a5832ba56fe50 500 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 8 492 31.329 T 13-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 THITH_14490 40fa9b2cf1275fe78e4a5832ba56fe50 500 Pfam PF08245 Mur ligase middle domain 111 319 3.2E-41 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 THITH_14490 40fa9b2cf1275fe78e4a5832ba56fe50 500 Pfam PF02875 Mur ligase family, glutamate ligase domain 340 424 5.0E-24 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 THITH_14490 40fa9b2cf1275fe78e4a5832ba56fe50 500 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 23 490 6.7E-134 T 13-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 THITH_14490 40fa9b2cf1275fe78e4a5832ba56fe50 500 Gene3D G3DSA:3.40.1190.10 104 342 6.8E-66 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THITH_08080 9f9c4b43a03e9bd018353ad7e2aed2c4 272 Pfam PF01936 NYN domain 10 153 1.0E-33 T 13-10-2018 IPR021139 NYN domain, limkain-b1-type THITH_08080 9f9c4b43a03e9bd018353ad7e2aed2c4 272 Pfam PF12872 OST-HTH/LOTUS domain 205 249 1.0E-5 T 13-10-2018 IPR025605 OST-HTH/LOTUS domain THITH_08080 9f9c4b43a03e9bd018353ad7e2aed2c4 272 Gene3D G3DSA:3.40.50.1010 4 157 3.0E-36 T 13-10-2018 THITH_13185 e1c4b7d6faf7c1f28df12a5a512450c0 155 Pfam PF00075 RNase H 8 144 1.3E-48 T 13-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 THITH_13185 e1c4b7d6faf7c1f28df12a5a512450c0 155 Hamap MF_00042 Ribonuclease H [rnhA]. 5 153 35.903 T 13-10-2018 IPR022892 Ribonuclease HI GO:0004523 THITH_13185 e1c4b7d6faf7c1f28df12a5a512450c0 155 SUPERFAMILY SSF53098 6 146 4.3E-58 T 13-10-2018 IPR012337 Ribonuclease H-like superfamily THITH_13185 e1c4b7d6faf7c1f28df12a5a512450c0 155 Gene3D G3DSA:3.30.420.10 4 153 4.7E-60 T 13-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 THITH_10815 1507abb3143b6981ea9689ea8e63334a 150 SUPERFAMILY SSF52833 4 146 7.29E-33 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_10815 1507abb3143b6981ea9689ea8e63334a 150 PIRSF PIRSF000239 1 148 4.9E-30 T 13-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THITH_10815 1507abb3143b6981ea9689ea8e63334a 150 Pfam PF00578 AhpC/TSA family 3 86 5.5E-18 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THITH_10815 1507abb3143b6981ea9689ea8e63334a 150 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 107 142 4.8E-5 T 13-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THITH_10815 1507abb3143b6981ea9689ea8e63334a 150 Gene3D G3DSA:3.40.30.10 1 143 9.0E-37 T 13-10-2018 THITH_12990 e34bb6d3ecaad6d04b116d40e794f875 118 Gene3D G3DSA:1.20.58.1610 1 118 5.4E-45 T 13-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12990 e34bb6d3ecaad6d04b116d40e794f875 118 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 118 20.519 T 13-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 THITH_12990 e34bb6d3ecaad6d04b116d40e794f875 118 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 21 117 6.7E-40 T 13-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_15120 48af319e6f16883c0b3e9be812a4367a 326 Pfam PF13362 Toprim domain 228 318 1.3E-9 T 13-10-2018 IPR006171 TOPRIM domain THITH_04090 11832bcf8e2b44686dbdc027f41618e0 254 Pfam PF07103 Protein of unknown function (DUF1365) 7 247 1.2E-66 T 13-10-2018 IPR010775 Protein of unknown function DUF1365 THITH_09225 3d8784b68410579bcef0de266e05a6fa 420 Pfam PF09664 Protein of unknown function C-terminus (DUF2399) 259 408 4.0E-46 T 13-10-2018 IPR024465 Domain of unknown function DUF2399 THITH_09225 3d8784b68410579bcef0de266e05a6fa 420 TIGRFAM TIGR02679 TIGR02679: TIGR02679 family protein 35 408 2.7E-102 T 13-10-2018 IPR013495 Conserved hypothetical protein CHP02679 THITH_09225 3d8784b68410579bcef0de266e05a6fa 420 Pfam PF11796 Protein of unknown function N-terminus (DUF3323) 35 237 1.5E-54 T 13-10-2018 IPR024466 Conserved hypothetical protein CHP02679, N terminus THITH_00805 58dd7a19edfe7d9dc1aa08446d002f47 160 Pfam PF03625 Domain of unknown function DUF302 81 128 1.0E-5 T 13-10-2018 IPR005180 Domain of unknown function DUF302 THITH_00805 58dd7a19edfe7d9dc1aa08446d002f47 160 Gene3D G3DSA:3.30.310.70 72 158 3.8E-9 T 13-10-2018 IPR035923 TT1751-like domain superfamily THITH_00805 58dd7a19edfe7d9dc1aa08446d002f47 160 SUPERFAMILY SSF103247 42 156 3.14E-11 T 13-10-2018 IPR035923 TT1751-like domain superfamily THITH_12615 a2a598f19d3e0c89c05fa63fdd8b74c4 424 Pfam PF04932 O-Antigen ligase 179 337 1.1E-11 T 13-10-2018 IPR007016 O-antigen ligase-related THITH_06140 df941a4018ceecd4f124c35d6c8f8291 730 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 725 0.0 T 13-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 THITH_06140 df941a4018ceecd4f124c35d6c8f8291 730 Gene3D G3DSA:1.20.1220.12 587 730 6.0E-71 T 13-10-2018 THITH_06140 df941a4018ceecd4f124c35d6c8f8291 730 SUPERFAMILY SSF51645 2 725 9.94E-301 T 13-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 THITH_06140 df941a4018ceecd4f124c35d6c8f8291 730 Gene3D G3DSA:2.170.170.11 135 264 3.2E-278 T 13-10-2018 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 THITH_06140 df941a4018ceecd4f124c35d6c8f8291 730 Hamap MF_00641 Malate synthase G [glcB]. 1 730 395.111 T 13-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 THITH_06140 df941a4018ceecd4f124c35d6c8f8291 730 Gene3D G3DSA:3.20.20.360 8 574 3.2E-278 T 13-10-2018 THITH_06140 df941a4018ceecd4f124c35d6c8f8291 730 Pfam PF01274 Malate synthase 19 701 2.0E-170 T 13-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 THITH_05545 99f0729b4cbd3d7c73a6e686e5c85ba9 418 Gene3D G3DSA:1.25.40.10 66 248 1.8E-6 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_05545 99f0729b4cbd3d7c73a6e686e5c85ba9 418 Gene3D G3DSA:2.60.120.260 251 412 1.4E-6 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily THITH_01245 65c822e2da710b39b7bdce22a67e5910 240 Pfam PF01553 Acyltransferase 61 185 2.5E-17 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 THITH_01245 65c822e2da710b39b7bdce22a67e5910 240 SUPERFAMILY SSF69593 35 236 3.92E-37 T 13-10-2018 THITH_01245 65c822e2da710b39b7bdce22a67e5910 240 SMART SM00563 74 188 1.1E-32 T 13-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 THITH_12745 4198d9bd30b9e7db1d72ac4d901c747b 191 Pfam PF02627 Carboxymuconolactone decarboxylase family 57 104 9.4E-8 T 13-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 THITH_12745 4198d9bd30b9e7db1d72ac4d901c747b 191 SUPERFAMILY SSF69118 7 181 1.31E-46 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 THITH_12745 4198d9bd30b9e7db1d72ac4d901c747b 191 Gene3D G3DSA:1.20.1290.10 16 180 5.2E-42 T 13-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 THITH_03410 b843e43bad7b4405480bb772ac9fd4e5 159 Pfam PF07505 Protein of unknown function (DUF5131) 1 153 1.4E-58 T 13-10-2018 IPR011101 Protein of unknown function DUF5131 THITH_11770 d0d150c958f53991faf341149504a05c 265 Pfam PF14355 Abortive infection C-terminus 173 243 3.1E-10 T 13-10-2018 IPR026001 Abortive infection protein-like, C-terminal domain THITH_08000 70117861ad21d737d9a9d0da02b08dc1 261 Gene3D G3DSA:3.40.50.150 34 205 7.4E-25 T 13-10-2018 THITH_08000 70117861ad21d737d9a9d0da02b08dc1 261 Pfam PF05050 Methyltransferase FkbM domain 44 174 5.4E-11 T 13-10-2018 IPR006342 Methyltransferase FkbM THITH_08000 70117861ad21d737d9a9d0da02b08dc1 261 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 42 175 6.0E-27 T 13-10-2018 IPR006342 Methyltransferase FkbM THITH_08000 70117861ad21d737d9a9d0da02b08dc1 261 SUPERFAMILY SSF53335 29 201 2.94E-33 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_08115 d39f920fc59a14f87455e46497f0347d 104 Gene3D G3DSA:3.90.10.10 25 102 4.3E-15 T 13-10-2018 THITH_08115 d39f920fc59a14f87455e46497f0347d 104 Pfam PF14522 Cytochrome c7 and related cytochrome c 39 101 4.2E-8 T 13-10-2018 IPR029467 C-type polyheme cytochrome OmcB THITH_08115 d39f920fc59a14f87455e46497f0347d 104 SUPERFAMILY SSF48695 31 101 7.58E-15 T 13-10-2018 IPR036280 Multiheme cytochrome superfamily THITH_08115 d39f920fc59a14f87455e46497f0347d 104 TIGRFAM TIGR04257 nanowire_3heme: c(7)-type cytochrome triheme domain 31 101 9.8E-16 T 13-10-2018 IPR026352 C(7)-type cytochrome triheme domain THITH_03085 6ab1e683deadb4c5e841ca92061dff87 735 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 462 622 1.7E-24 T 13-10-2018 IPR035089 Tail sheath protein, subtilisin-like domain THITH_03085 6ab1e683deadb4c5e841ca92061dff87 735 Pfam PF17482 Phage tail sheath C-terminal domain 623 729 2.1E-12 T 13-10-2018 IPR020287 Tail sheath protein, C-terminal domain THITH_15210 f117872f6a6ba4bfcd229995c43e2dd5 592 Pfam PF17243 POTRA domain TamA domain 1 42 118 1.7E-15 T 13-10-2018 IPR035243 TamA, POTRA domain 1 THITH_15210 f117872f6a6ba4bfcd229995c43e2dd5 592 Gene3D G3DSA:3.10.20.310 39 119 4.8E-6 T 13-10-2018 THITH_15210 f117872f6a6ba4bfcd229995c43e2dd5 592 Gene3D G3DSA:3.10.20.310 208 283 7.6E-22 T 13-10-2018 THITH_15210 f117872f6a6ba4bfcd229995c43e2dd5 592 Gene3D G3DSA:2.40.160.50 284 592 3.8E-95 T 13-10-2018 THITH_15210 f117872f6a6ba4bfcd229995c43e2dd5 592 Gene3D G3DSA:3.10.20.310 121 207 5.8E-21 T 13-10-2018 THITH_15210 f117872f6a6ba4bfcd229995c43e2dd5 592 Pfam PF01103 Surface antigen 312 589 4.3E-35 T 13-10-2018 IPR000184 Bacterial surface antigen (D15) GO:0019867 Reactome: R-HSA-1268020|Reactome: R-HSA-8949613 THITH_11585 a61e37b9387f64752d72e4bc3cad63d4 461 SUPERFAMILY SSF48208 10 435 7.37E-48 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 THITH_11585 a61e37b9387f64752d72e4bc3cad63d4 461 Pfam PF12899 Alkaline and neutral invertase 9 442 3.5E-195 T 13-10-2018 IPR024746 Glycosyl hydrolase family 100 GO:0033926 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 THITH_11585 a61e37b9387f64752d72e4bc3cad63d4 461 Gene3D G3DSA:1.50.10.10 38 272 5.4E-11 T 13-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 THITH_17430 dc0134e40346dae89d1767ef48d83f73 716 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 147 706 1.9E-191 T 13-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ THITH_17430 dc0134e40346dae89d1767ef48d83f73 716 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 204 634 2.7E-87 T 13-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit THITH_03810 4b0ae2168d96b9c6e2ccda354587ccee 141 SUPERFAMILY SSF102400 1 139 5.1E-39 T 13-10-2018 IPR036768 DNA polymerase III subunit chi superfamily THITH_03810 4b0ae2168d96b9c6e2ccda354587ccee 141 Gene3D G3DSA:3.40.50.10110 1 139 2.0E-41 T 13-10-2018 IPR036768 DNA polymerase III subunit chi superfamily THITH_03810 4b0ae2168d96b9c6e2ccda354587ccee 141 Pfam PF04364 DNA polymerase III chi subunit, HolC 1 134 6.3E-37 T 13-10-2018 IPR007459 DNA polymerase III chi subunit, HolC GO:0003677|GO:0003887|GO:0006260 THITH_05875 47cf15a9b7f0d010277863034a3fe2c6 298 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 36 264 2.0E-34 T 13-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system THITH_05875 47cf15a9b7f0d010277863034a3fe2c6 298 Gene3D G3DSA:3.10.450.620 27 96 1.0E-6 T 13-10-2018 THITH_03385 a800a86a4a2cae79d67ad36b41c0ee56 96 SUPERFAMILY SSF81301 11 96 3.02E-20 T 13-10-2018 THITH_03385 a800a86a4a2cae79d67ad36b41c0ee56 96 Pfam PF01909 Nucleotidyltransferase domain 15 95 1.9E-13 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THITH_03385 a800a86a4a2cae79d67ad36b41c0ee56 96 Gene3D G3DSA:3.30.460.10 1 96 1.1E-24 T 13-10-2018 THITH_02385 e56c9dd87241d2b2f9615905e1f90277 415 Gene3D G3DSA:3.50.50.60 1 73 1.5E-14 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_02385 e56c9dd87241d2b2f9615905e1f90277 415 Pfam PF01266 FAD dependent oxidoreductase 2 396 2.0E-67 T 13-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 THITH_02385 e56c9dd87241d2b2f9615905e1f90277 415 Gene3D G3DSA:3.30.9.10 134 364 5.9E-55 T 13-10-2018 THITH_02385 e56c9dd87241d2b2f9615905e1f90277 415 SUPERFAMILY SSF51905 1 413 6.34E-53 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_02385 e56c9dd87241d2b2f9615905e1f90277 415 SUPERFAMILY SSF54373 270 360 1.19E-14 T 13-10-2018 THITH_02385 e56c9dd87241d2b2f9615905e1f90277 415 Gene3D G3DSA:3.50.50.60 102 406 5.9E-55 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_02730 2ab77796128194bc9a6b85992aa03311 310 Gene3D G3DSA:1.10.10.10 1 90 1.0E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_02730 2ab77796128194bc9a6b85992aa03311 310 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.0E-20 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_02730 2ab77796128194bc9a6b85992aa03311 310 Gene3D G3DSA:3.40.190.290 91 300 7.2E-50 T 13-10-2018 THITH_02730 2ab77796128194bc9a6b85992aa03311 310 SUPERFAMILY SSF53850 90 296 3.02E-48 T 13-10-2018 THITH_02730 2ab77796128194bc9a6b85992aa03311 310 Pfam PF03466 LysR substrate binding domain 88 295 1.4E-51 T 13-10-2018 IPR005119 LysR, substrate-binding THITH_02730 2ab77796128194bc9a6b85992aa03311 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.2E-10 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_02730 2ab77796128194bc9a6b85992aa03311 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.2E-10 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_02730 2ab77796128194bc9a6b85992aa03311 310 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.2E-10 T 13-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 THITH_02730 2ab77796128194bc9a6b85992aa03311 310 SUPERFAMILY SSF46785 2 87 4.05E-24 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_13380 b7450e074a35ac68bdd7ddb60a9a3075 89 Gene3D G3DSA:2.10.260.10 3 48 1.4E-8 T 13-10-2018 THITH_13380 b7450e074a35ac68bdd7ddb60a9a3075 89 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 10 49 3.2E-10 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THITH_13380 b7450e074a35ac68bdd7ddb60a9a3075 89 SMART SM00966 10 55 9.2E-8 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THITH_13380 b7450e074a35ac68bdd7ddb60a9a3075 89 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 11 50 2.2E-7 T 13-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 THITH_13380 b7450e074a35ac68bdd7ddb60a9a3075 89 SUPERFAMILY SSF89447 9 51 1.23E-9 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily THITH_17425 33d0621ae0437d99b0d26a573f649d12 227 Gene3D G3DSA:1.10.760.10 43 131 2.0E-17 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_17425 33d0621ae0437d99b0d26a573f649d12 227 PIRSF PIRSF000005 5 227 9.1E-46 T 13-10-2018 IPR024167 Cytochrome c4-like GO:0005506|GO:0009055|GO:0020037|GO:0042597 THITH_17425 33d0621ae0437d99b0d26a573f649d12 227 Gene3D G3DSA:1.10.760.10 142 227 2.1E-22 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_17425 33d0621ae0437d99b0d26a573f649d12 227 SUPERFAMILY SSF46626 136 226 3.58E-18 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_17425 33d0621ae0437d99b0d26a573f649d12 227 SUPERFAMILY SSF46626 42 127 1.4E-16 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_17425 33d0621ae0437d99b0d26a573f649d12 227 Pfam PF00034 Cytochrome c 158 224 3.5E-6 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_17425 33d0621ae0437d99b0d26a573f649d12 227 Pfam PF00034 Cytochrome c 52 126 3.3E-5 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_04700 3a98e82b65f84e6e7219e6fef2c0c01d 299 SUPERFAMILY SSF51735 5 222 2.48E-34 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_04700 3a98e82b65f84e6e7219e6fef2c0c01d 299 Pfam PF13460 NAD(P)H-binding 11 169 6.2E-7 T 13-10-2018 IPR016040 NAD(P)-binding domain THITH_04700 3a98e82b65f84e6e7219e6fef2c0c01d 299 Gene3D G3DSA:3.90.25.10 121 254 3.6E-47 T 13-10-2018 THITH_04700 3a98e82b65f84e6e7219e6fef2c0c01d 299 Gene3D G3DSA:3.40.50.720 7 252 3.6E-47 T 13-10-2018 THITH_06770 e09f4d1f624e02e2e7b46263baf6aed8 142 Pfam PF04809 HupH hydrogenase expression protein, C-terminal conserved region 23 135 4.3E-32 T 13-10-2018 IPR006894 HupH hydrogenase expression protein, C-terminal THITH_06770 e09f4d1f624e02e2e7b46263baf6aed8 142 Gene3D G3DSA:3.30.1370.140 20 117 1.7E-28 T 13-10-2018 IPR038527 HupH, C-terminal domain superfamily THITH_06770 e09f4d1f624e02e2e7b46263baf6aed8 142 ProDom PD005668 HYDROGENASE HUPH HYDROGENASE-1 EXPRESSION/FORMATION OPERON PROTEIN C-TERMINAL EXPRESSION HYAF HOXQ 23 123 3.0E-13 T 13-10-2018 IPR006894 HupH hydrogenase expression protein, C-terminal THITH_12025 5a063c30fd315b70a16b7b9d32ff0a08 161 SUPERFAMILY SSF48695 36 119 5.2E-10 T 13-10-2018 IPR036280 Multiheme cytochrome superfamily THITH_16715 033febc7c321daddae153dfa09201135 327 Pfam PF03773 Predicted permease 25 315 1.7E-66 T 13-10-2018 IPR005524 Predicted permease DUF318 THITH_00180 8f30cf02ea1b96412a9e3c30a385d1ce 184 SUPERFAMILY SSF52980 9 180 6.43E-24 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_00180 8f30cf02ea1b96412a9e3c30a385d1ce 184 Gene3D G3DSA:3.90.1570.10 3 184 5.8E-20 T 13-10-2018 THITH_00180 8f30cf02ea1b96412a9e3c30a385d1ce 184 Pfam PF05685 Putative restriction endonuclease 14 158 5.2E-29 T 13-10-2018 IPR008538 Domain of unknown function DUF820 THITH_00900 6ba5ad96c2402fdedd63219faff66e7f 251 Gene3D G3DSA:3.40.190.10 129 233 3.8E-6 T 13-10-2018 THITH_00900 6ba5ad96c2402fdedd63219faff66e7f 251 Gene3D G3DSA:3.40.190.10 3 106 3.1E-5 T 13-10-2018 THITH_00900 6ba5ad96c2402fdedd63219faff66e7f 251 Pfam PF12974 ABC transporter, phosphonate, periplasmic substrate-binding protein 24 237 1.3E-29 T 13-10-2018 THITH_00900 6ba5ad96c2402fdedd63219faff66e7f 251 SUPERFAMILY SSF53850 29 223 5.35E-13 T 13-10-2018 THITH_03100 4cdaa856d4e35004a39a1ae7a4edc11f 168 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 5 158 2.8E-22 T 13-10-2018 IPR011747 Conserved hypothetical protein CHP02241 THITH_03100 4cdaa856d4e35004a39a1ae7a4edc11f 168 Pfam PF06841 T4-like virus tail tube protein gp19 6 158 2.8E-26 T 13-10-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 THITH_06975 aa16b7321c245d7156fa8e2c46aae046 178 Gene3D G3DSA:2.20.70.10 11 36 2.3E-8 T 13-10-2018 THITH_06975 aa16b7321c245d7156fa8e2c46aae046 178 Pfam PF14803 Nudix N-terminal 13 36 6.4E-10 T 13-10-2018 IPR029401 Nudix hydrolase, N-terminal KEGG: 00230+3.6.1.13|KEGG: 00740+3.6.1.18 THITH_06975 aa16b7321c245d7156fa8e2c46aae046 178 SUPERFAMILY SSF55811 15 162 5.28E-36 T 13-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 THITH_06975 aa16b7321c245d7156fa8e2c46aae046 178 Pfam PF00293 NUDIX domain 40 143 5.1E-12 T 13-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 THITH_06975 aa16b7321c245d7156fa8e2c46aae046 178 Gene3D G3DSA:3.90.79.10 37 173 2.7E-36 T 13-10-2018 THITH_11775 ffacadd20d12dd2155f8a397266e3812 613 Pfam PF03235 Protein of unknown function DUF262 22 251 3.2E-27 T 13-10-2018 IPR004919 Domain of unknown function DUF262 THITH_01715 5447878bb9d4abd9579beb6cd4da36ca 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 579 595 2.3E-10 T 13-10-2018 THITH_01715 5447878bb9d4abd9579beb6cd4da36ca 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 660 679 2.3E-10 T 13-10-2018 THITH_01715 5447878bb9d4abd9579beb6cd4da36ca 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 720 738 2.3E-10 T 13-10-2018 THITH_01715 5447878bb9d4abd9579beb6cd4da36ca 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 74 93 2.3E-10 T 13-10-2018 THITH_01715 5447878bb9d4abd9579beb6cd4da36ca 816 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 690 709 2.3E-10 T 13-10-2018 THITH_01715 5447878bb9d4abd9579beb6cd4da36ca 816 Gene3D G3DSA:1.10.8.60 464 550 4.6E-10 T 13-10-2018 THITH_01715 5447878bb9d4abd9579beb6cd4da36ca 816 Gene3D G3DSA:3.30.230.10 555 802 2.3E-93 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THITH_01715 5447878bb9d4abd9579beb6cd4da36ca 816 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 663 765 1.1E-9 T 13-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 THITH_01715 5447878bb9d4abd9579beb6cd4da36ca 816 Gene3D G3DSA:3.40.50.300 251 463 2.2E-64 T 13-10-2018 THITH_01715 5447878bb9d4abd9579beb6cd4da36ca 816 Gene3D G3DSA:3.40.50.300 18 182 5.6E-29 T 13-10-2018 THITH_01715 5447878bb9d4abd9579beb6cd4da36ca 816 SUPERFAMILY SSF52540 43 565 2.17E-10 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01715 5447878bb9d4abd9579beb6cd4da36ca 816 Pfam PF13654 AAA domain 38 553 2.9E-197 T 13-10-2018 THITH_01715 5447878bb9d4abd9579beb6cd4da36ca 816 SUPERFAMILY SSF54211 577 771 9.86E-34 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_06620 1e15ce867511102915eca01d02b940d7 226 Pfam PF01027 Inhibitor of apoptosis-promoting Bax1 23 219 7.8E-42 T 13-10-2018 IPR006214 Bax inhibitor 1-related THITH_12440 d7c31204f2d33a12cb61119d9d323d43 675 Gene3D G3DSA:2.60.120.260 351 539 1.7E-39 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily THITH_12440 d7c31204f2d33a12cb61119d9d323d43 675 SUPERFAMILY SSF49785 291 531 2.55E-55 T 13-10-2018 IPR008979 Galactose-binding-like domain superfamily THITH_12440 d7c31204f2d33a12cb61119d9d323d43 675 TIGRFAM TIGR00976 /NonD: hydrolase CocE/NonD family protein 20 506 2.7E-68 T 13-10-2018 IPR005674 CocE/Serine esterase GO:0016787 THITH_12440 d7c31204f2d33a12cb61119d9d323d43 675 Gene3D G3DSA:1.10.3020.10 154 227 2.1E-64 T 13-10-2018 THITH_12440 d7c31204f2d33a12cb61119d9d323d43 675 SMART SM00939 291 542 4.3E-80 T 13-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 THITH_12440 d7c31204f2d33a12cb61119d9d323d43 675 Gene3D G3DSA:3.40.50.1820 17 312 2.1E-64 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_12440 d7c31204f2d33a12cb61119d9d323d43 675 SUPERFAMILY SSF53474 7 338 1.16E-76 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_12440 d7c31204f2d33a12cb61119d9d323d43 675 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 23 274 1.3E-63 T 13-10-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 THITH_12440 d7c31204f2d33a12cb61119d9d323d43 675 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 304 524 7.3E-53 T 13-10-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 THITH_03415 163b14b1e25f9cba96ab8e5ffc460556 156 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 86 132 1.9E-13 T 13-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 THITH_03415 163b14b1e25f9cba96ab8e5ffc460556 156 Pfam PF12728 Helix-turn-helix domain 87 133 5.7E-9 T 13-10-2018 THITH_11695 67fa650c67bdc3c41b75feb8d2082b07 349 Pfam PF03916 Polysulphide reductase, NrfD 41 296 4.5E-6 T 13-10-2018 IPR005614 NrfD family THITH_02855 f6904c4d55a894821a576f131d00acf9 283 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 136 164 - T 13-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 THITH_02855 f6904c4d55a894821a576f131d00acf9 283 SUPERFAMILY SSF51735 6 275 1.64E-60 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_02855 f6904c4d55a894821a576f131d00acf9 283 Pfam PF00106 short chain dehydrogenase 7 189 2.3E-42 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_02855 f6904c4d55a894821a576f131d00acf9 283 Gene3D G3DSA:3.40.50.720 5 274 8.2E-63 T 13-10-2018 THITH_02855 f6904c4d55a894821a576f131d00acf9 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 9.9E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_02855 f6904c4d55a894821a576f131d00acf9 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 9.9E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_02855 f6904c4d55a894821a576f131d00acf9 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 9.9E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_02855 f6904c4d55a894821a576f131d00acf9 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 9.9E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_02855 f6904c4d55a894821a576f131d00acf9 283 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 9.9E-18 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_03495 cc3085895512a8e9cdad762603324cc6 557 Pfam PF00390 Malic enzyme, N-terminal domain 85 265 8.4E-73 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 THITH_03495 cc3085895512a8e9cdad762603324cc6 557 SMART SM00919 275 526 7.9E-106 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 THITH_03495 cc3085895512a8e9cdad762603324cc6 557 Gene3D G3DSA:3.40.50.10380 19 272 2.6E-116 T 13-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 THITH_03495 cc3085895512a8e9cdad762603324cc6 557 Gene3D G3DSA:3.40.50.720 273 557 3.0E-117 T 13-10-2018 THITH_03495 cc3085895512a8e9cdad762603324cc6 557 PRINTS PR00072 Malic enzyme signature 91 115 3.1E-77 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 THITH_03495 cc3085895512a8e9cdad762603324cc6 557 PRINTS PR00072 Malic enzyme signature 302 318 3.1E-77 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 THITH_03495 cc3085895512a8e9cdad762603324cc6 557 PRINTS PR00072 Malic enzyme signature 151 180 3.1E-77 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 THITH_03495 cc3085895512a8e9cdad762603324cc6 557 PRINTS PR00072 Malic enzyme signature 403 419 3.1E-77 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 THITH_03495 cc3085895512a8e9cdad762603324cc6 557 PRINTS PR00072 Malic enzyme signature 187 209 3.1E-77 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 THITH_03495 cc3085895512a8e9cdad762603324cc6 557 PRINTS PR00072 Malic enzyme signature 271 287 3.1E-77 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 THITH_03495 cc3085895512a8e9cdad762603324cc6 557 PRINTS PR00072 Malic enzyme signature 246 264 3.1E-77 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 THITH_03495 cc3085895512a8e9cdad762603324cc6 557 PIRSF PIRSF000106 14 557 9.6E-222 T 13-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 THITH_03495 cc3085895512a8e9cdad762603324cc6 557 SMART SM01274 85 265 6.7E-99 T 13-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 THITH_03495 cc3085895512a8e9cdad762603324cc6 557 SUPERFAMILY SSF53223 13 274 9.35E-104 T 13-10-2018 THITH_03495 cc3085895512a8e9cdad762603324cc6 557 ProSitePatterns PS00331 Malic enzymes signature. 271 287 - T 13-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 THITH_03495 cc3085895512a8e9cdad762603324cc6 557 Pfam PF03949 Malic enzyme, NAD binding domain 275 525 1.2E-97 T 13-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 THITH_03495 cc3085895512a8e9cdad762603324cc6 557 SUPERFAMILY SSF51735 275 556 2.19E-94 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_16195 c68bd51528e21a132558bedfbb67e0f5 172 Pfam PF08534 Redoxin 33 155 5.0E-15 T 13-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 THITH_16195 c68bd51528e21a132558bedfbb67e0f5 172 SUPERFAMILY SSF52833 38 170 4.2E-30 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_16195 c68bd51528e21a132558bedfbb67e0f5 172 Gene3D G3DSA:3.40.30.10 21 172 1.1E-37 T 13-10-2018 THITH_16195 c68bd51528e21a132558bedfbb67e0f5 172 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 24 168 1.1E-40 T 13-10-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 THITH_13850 c5b08a8a3a36c2beb2b92ce79ae84f73 108 SUPERFAMILY SSF51182 36 107 5.75E-19 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily THITH_13850 c5b08a8a3a36c2beb2b92ce79ae84f73 108 Gene3D G3DSA:2.60.120.10 18 107 5.3E-32 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_13850 c5b08a8a3a36c2beb2b92ce79ae84f73 108 Pfam PF07883 Cupin domain 42 102 2.6E-14 T 13-10-2018 IPR013096 Cupin 2, conserved barrel THITH_08995 0ed63514a5409d80a2e22299df42af42 173 Gene3D G3DSA:1.10.287.950 41 163 2.4E-6 T 13-10-2018 THITH_08995 0ed63514a5409d80a2e22299df42af42 173 SUPERFAMILY SSF58104 81 156 5.89E-6 T 13-10-2018 THITH_12015 877a46a66ce5890734c6ec47467704b7 498 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 145 156 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_12015 877a46a66ce5890734c6ec47467704b7 498 Pfam PF13183 4Fe-4S dicluster domain 74 159 9.5E-10 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_12015 877a46a66ce5890734c6ec47467704b7 498 SUPERFAMILY SSF46548 66 173 2.79E-14 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_09245 f70504d69bbfef0fd8d4a925cb3fd721 329 Pfam PF01867 CRISPR associated protein Cas1 6 289 3.6E-71 T 13-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THITH_09245 f70504d69bbfef0fd8d4a925cb3fd721 329 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 1 308 20.116 T 13-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THITH_09245 f70504d69bbfef0fd8d4a925cb3fd721 329 Gene3D G3DSA:1.20.120.920 85 318 4.3E-65 T 13-10-2018 THITH_09245 f70504d69bbfef0fd8d4a925cb3fd721 329 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 13 292 1.9E-55 T 13-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THITH_04010 132375c8650ac152ac6d62cb55c65b4d 172 Gene3D G3DSA:3.10.450.50 134 170 1.1E-9 T 13-10-2018 THITH_04010 132375c8650ac152ac6d62cb55c65b4d 172 SUPERFAMILY SSF103642 150 170 4.41E-8 T 13-10-2018 THITH_04010 132375c8650ac152ac6d62cb55c65b4d 172 Pfam PF02810 SEC-C motif 152 169 2.3E-10 T 13-10-2018 IPR004027 SEC-C motif THITH_08430 0aa609b25896f94e28458f9e5a21ffea 276 Pfam PF12679 ABC-2 family transporter protein 5 275 8.0E-44 T 13-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 THITH_13155 b9424df797c214e548462a09c7c85012 107 Gene3D G3DSA:3.30.1450.10 29 106 1.2E-23 T 13-10-2018 IPR037873 BamE-like THITH_13155 b9424df797c214e548462a09c7c85012 107 Hamap MF_00925 Outer membrane protein assembly factor BamE [bamE]. 5 107 22.999 T 13-10-2018 IPR026592 Outer membrane protein assembly factor BamE THITH_13155 b9424df797c214e548462a09c7c85012 107 Pfam PF04355 SmpA / OmlA family 30 99 5.2E-20 T 13-10-2018 IPR007450 Lipoprotein SmpA/OmlA GO:0019867 THITH_00290 27269b389a66e244d4db11504a5f1338 90 Pfam PF12441 CopG antitoxin of type II toxin-antitoxin system 11 83 1.6E-24 T 13-10-2018 IPR022148 CopG antitoxin THITH_00290 27269b389a66e244d4db11504a5f1338 90 SUPERFAMILY SSF47598 45 89 2.35E-6 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 THITH_07495 8006a6338a857e22ca24aeb0db8a69e7 303 Pfam PF13649 Methyltransferase domain 77 168 6.0E-16 T 13-10-2018 THITH_07495 8006a6338a857e22ca24aeb0db8a69e7 303 SUPERFAMILY SSF53335 14 289 5.43E-36 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_07495 8006a6338a857e22ca24aeb0db8a69e7 303 Gene3D G3DSA:3.40.50.150 4 256 7.3E-41 T 13-10-2018 THITH_14465 957936713722d77172287bcb5b3a4e53 367 Gene3D G3DSA:3.40.50.2000 165 342 1.1E-115 T 13-10-2018 THITH_14465 957936713722d77172287bcb5b3a4e53 367 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 2 353 1.3E-105 T 13-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_14465 957936713722d77172287bcb5b3a4e53 367 SUPERFAMILY SSF53756 7 359 7.46E-124 T 13-10-2018 THITH_14465 957936713722d77172287bcb5b3a4e53 367 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 8 358 36.498 T 13-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_14465 957936713722d77172287bcb5b3a4e53 367 Gene3D G3DSA:3.40.50.2000 9 348 1.1E-115 T 13-10-2018 THITH_14465 957936713722d77172287bcb5b3a4e53 367 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 8 145 7.4E-40 T 13-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_14465 957936713722d77172287bcb5b3a4e53 367 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 349 5.8E-40 T 13-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 THITH_00025 e3ff2af04d06a1d874a6772352f2bbf6 191 Pfam PF04011 LemA family 7 185 2.6E-52 T 13-10-2018 IPR007156 LemA THITH_00025 e3ff2af04d06a1d874a6772352f2bbf6 191 Gene3D G3DSA:1.20.1440.20 16 185 3.6E-45 T 13-10-2018 IPR023353 LemA-like domain superfamily THITH_00025 e3ff2af04d06a1d874a6772352f2bbf6 191 SUPERFAMILY SSF140478 26 176 6.8E-41 T 13-10-2018 IPR023353 LemA-like domain superfamily THITH_00385 61af2280ee3a743bb84975ce3a203c23 194 Gene3D G3DSA:3.90.1570.10 4 185 4.6E-19 T 13-10-2018 THITH_00385 61af2280ee3a743bb84975ce3a203c23 194 SUPERFAMILY SSF52980 6 161 4.08E-23 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_00385 61af2280ee3a743bb84975ce3a203c23 194 Pfam PF05685 Putative restriction endonuclease 13 164 3.3E-26 T 13-10-2018 IPR008538 Domain of unknown function DUF820 THITH_04375 45a7860db2b908866cd093f27ae96dad 524 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 135 282 3.0E-50 T 13-10-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04375 45a7860db2b908866cd093f27ae96dad 524 Pfam PF13237 4Fe-4S dicluster domain 376 426 2.4E-6 T 13-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain THITH_04375 45a7860db2b908866cd093f27ae96dad 524 Hamap MF_00461 Ion-translocating oxidoreductase complex subunit C [rsxC]. 1 524 181.953 T 13-10-2018 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 THITH_04375 45a7860db2b908866cd093f27ae96dad 524 Pfam PF13375 RnfC Barrel sandwich hybrid domain 8 109 7.7E-33 T 13-10-2018 IPR026902 RnfC Barrel sandwich hybrid domain THITH_04375 45a7860db2b908866cd093f27ae96dad 524 Gene3D G3DSA:1.10.1060.10 371 443 5.5E-12 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_04375 45a7860db2b908866cd093f27ae96dad 524 Pfam PF10531 SLBB domain 295 344 1.1E-14 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04375 45a7860db2b908866cd093f27ae96dad 524 Gene3D G3DSA:3.40.50.11540 140 289 9.4E-16 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04375 45a7860db2b908866cd093f27ae96dad 524 SUPERFAMILY SSF46548 325 441 2.09E-18 T 13-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 THITH_04375 45a7860db2b908866cd093f27ae96dad 524 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 415 426 - T 13-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site THITH_04375 45a7860db2b908866cd093f27ae96dad 524 TIGRFAM TIGR01945 rnfC: electron transport complex, RnfABCDGE type, C subunit 6 445 1.8E-176 T 13-10-2018 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC GO:0009055|GO:0016020|GO:0051539 THITH_04375 45a7860db2b908866cd093f27ae96dad 524 SUPERFAMILY SSF142019 89 303 8.24E-60 T 13-10-2018 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10280 01ede3da3ce32c730ee25b6a3a763691 295 SMART SM00267 103 280 5.3E-61 T 13-10-2018 IPR000160 GGDEF domain THITH_10280 01ede3da3ce32c730ee25b6a3a763691 295 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 113 278 1.4E-49 T 13-10-2018 IPR000160 GGDEF domain THITH_10280 01ede3da3ce32c730ee25b6a3a763691 295 Pfam PF00990 Diguanylate cyclase, GGDEF domain 116 276 5.3E-49 T 13-10-2018 IPR000160 GGDEF domain THITH_10280 01ede3da3ce32c730ee25b6a3a763691 295 Gene3D G3DSA:3.30.70.270 109 279 5.6E-57 T 13-10-2018 THITH_10280 01ede3da3ce32c730ee25b6a3a763691 295 SUPERFAMILY SSF55073 121 278 4.97E-48 T 13-10-2018 IPR029787 Nucleotide cyclase THITH_07840 9b826da3e447f6eb4a4fc19ba802fde5 157 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 148 2.6E-42 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I THITH_07840 9b826da3e447f6eb4a4fc19ba802fde5 157 Gene3D G3DSA:3.40.50.2300 1 157 8.3E-59 T 13-10-2018 THITH_07840 9b826da3e447f6eb4a4fc19ba802fde5 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 3 20 4.0E-24 T 13-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THITH_07840 9b826da3e447f6eb4a4fc19ba802fde5 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 122 137 4.0E-24 T 13-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THITH_07840 9b826da3e447f6eb4a4fc19ba802fde5 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 103 116 4.0E-24 T 13-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THITH_07840 9b826da3e447f6eb4a4fc19ba802fde5 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 46 62 4.0E-24 T 13-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THITH_07840 9b826da3e447f6eb4a4fc19ba802fde5 157 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 80 95 4.0E-24 T 13-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 THITH_07840 9b826da3e447f6eb4a4fc19ba802fde5 157 SUPERFAMILY SSF52788 2 151 6.02E-52 T 13-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily THITH_07840 9b826da3e447f6eb4a4fc19ba802fde5 157 SMART SM00226 1 150 2.7E-53 T 13-10-2018 IPR023485 Phosphotyrosine protein phosphatase I THITH_17025 e6087d6e1f2bee32c715c5a88e3a1b46 462 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 4 452 38.493 T 13-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 THITH_17025 e6087d6e1f2bee32c715c5a88e3a1b46 462 Pfam PF12804 MobA-like NTP transferase domain 7 122 2.6E-21 T 13-10-2018 IPR025877 MobA-like NTP transferase THITH_17025 e6087d6e1f2bee32c715c5a88e3a1b46 462 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 269 300 2.7E-6 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_17025 e6087d6e1f2bee32c715c5a88e3a1b46 462 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 317 350 3.5E-4 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_17025 e6087d6e1f2bee32c715c5a88e3a1b46 462 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 396 429 2.8E-7 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_17025 e6087d6e1f2bee32c715c5a88e3a1b46 462 Gene3D G3DSA:2.160.10.10 228 455 4.9E-62 T 13-10-2018 THITH_17025 e6087d6e1f2bee32c715c5a88e3a1b46 462 SUPERFAMILY SSF51161 257 436 4.63E-48 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily THITH_17025 e6087d6e1f2bee32c715c5a88e3a1b46 462 Gene3D G3DSA:3.90.550.10 2 227 4.3E-53 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_17025 e6087d6e1f2bee32c715c5a88e3a1b46 462 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 6 454 1.3E-164 T 13-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 THITH_17025 e6087d6e1f2bee32c715c5a88e3a1b46 462 SUPERFAMILY SSF53448 5 249 1.4E-50 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_09750 fddfcf3d5519ec0ae54e8cf12f5aaeef 147 Pfam PF10066 Uncharacterized conserved protein (DUF2304) 4 107 3.4E-23 T 13-10-2018 IPR019277 Protein of unknown function DUF2304 THITH_14750 4372456a2df56b8aee505423b17229aa 887 Gene3D G3DSA:3.40.50.970 471 705 2.9E-110 T 13-10-2018 THITH_14750 4372456a2df56b8aee505423b17229aa 887 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 8 886 0.0 T 13-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 THITH_14750 4372456a2df56b8aee505423b17229aa 887 SUPERFAMILY SSF52518 472 700 1.17E-97 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold THITH_14750 4372456a2df56b8aee505423b17229aa 887 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 81 293 1.2E-6 T 13-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 THITH_14750 4372456a2df56b8aee505423b17229aa 887 SUPERFAMILY SSF52922 701 885 5.41E-58 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 THITH_14750 4372456a2df56b8aee505423b17229aa 887 SUPERFAMILY SSF52518 58 468 6.88E-139 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold THITH_14750 4372456a2df56b8aee505423b17229aa 887 Gene3D G3DSA:3.40.50.970 57 470 8.3E-131 T 13-10-2018 THITH_14750 4372456a2df56b8aee505423b17229aa 887 PIRSF PIRSF000156 1 887 0.0 T 13-10-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 THITH_14750 4372456a2df56b8aee505423b17229aa 887 Gene3D G3DSA:3.40.50.920 706 887 1.9E-73 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 THITH_07170 a4a0d708a3a7417fe6494fb5fbed312c 122 SUPERFAMILY SSF54913 2 99 1.3E-10 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THITH_07170 a4a0d708a3a7417fe6494fb5fbed312c 122 Gene3D G3DSA:3.30.70.120 1 97 3.8E-8 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THITH_14635 081a1c3622bd21f5016841aa45486a2d 326 Gene3D G3DSA:3.40.50.10490 4 196 4.5E-64 T 13-10-2018 THITH_14635 081a1c3622bd21f5016841aa45486a2d 326 SMART SM00116 276 325 0.015 T 13-10-2018 IPR000644 CBS domain THITH_14635 081a1c3622bd21f5016841aa45486a2d 326 SMART SM00116 211 259 53.0 T 13-10-2018 IPR000644 CBS domain THITH_14635 081a1c3622bd21f5016841aa45486a2d 326 Pfam PF01380 SIS domain 42 173 7.9E-33 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 THITH_14635 081a1c3622bd21f5016841aa45486a2d 326 TIGRFAM TIGR00393 kpsF: sugar isomerase, KpsF/GutQ family 46 316 1.5E-110 T 13-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 THITH_14635 081a1c3622bd21f5016841aa45486a2d 326 PIRSF PIRSF004692 2 326 1.0E-129 T 13-10-2018 IPR004800 Phosphosugar isomerase, KdsD/KpsF-type GO:0005975|GO:0016853 THITH_14635 081a1c3622bd21f5016841aa45486a2d 326 SUPERFAMILY SSF53697 8 326 2.67E-65 T 13-10-2018 THITH_14635 081a1c3622bd21f5016841aa45486a2d 326 Pfam PF00571 CBS domain 202 258 4.3E-5 T 13-10-2018 IPR000644 CBS domain THITH_14635 081a1c3622bd21f5016841aa45486a2d 326 Pfam PF00571 CBS domain 269 323 2.3E-9 T 13-10-2018 IPR000644 CBS domain THITH_14635 081a1c3622bd21f5016841aa45486a2d 326 Gene3D G3DSA:3.10.580.10 197 323 2.7E-44 T 13-10-2018 THITH_16655 aa98ec0f17824d0c505819369a9711ec 114 Pfam PF11074 Domain of unknown function(DUF2779) 2 43 2.2E-7 T 13-10-2018 IPR021301 Domain of unknown functionDUF2779 THITH_09050 3b852a4089fa59072003f81547604e60 718 SUPERFAMILY SSF102114 334 606 2.75E-11 T 13-10-2018 THITH_09050 3b852a4089fa59072003f81547604e60 718 Gene3D G3DSA:3.80.30.20 368 610 2.2E-13 T 13-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe THITH_09050 3b852a4089fa59072003f81547604e60 718 TIGRFAM TIGR03904 SAM_YgiQ: uncharacterized radical SAM protein YgiQ 23 638 6.7E-259 T 13-10-2018 IPR022946 Uncharacterised protein family UPF0313 THITH_09050 3b852a4089fa59072003f81547604e60 718 Pfam PF04055 Radical SAM superfamily 373 578 6.2E-22 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THITH_09050 3b852a4089fa59072003f81547604e60 718 Pfam PF08497 Radical SAM N-terminal 23 372 1.4E-143 T 13-10-2018 IPR013704 Uncharacterised protein family UPF0313, N-terminal THITH_09050 3b852a4089fa59072003f81547604e60 718 SMART SM00729 369 625 2.2E-8 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THITH_09050 3b852a4089fa59072003f81547604e60 718 Hamap MF_01251 UPF0313 protein YgiQ [ygiQ]. 23 640 49.744 T 13-10-2018 IPR022946 Uncharacterised protein family UPF0313 THITH_09050 3b852a4089fa59072003f81547604e60 718 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 373 393 - T 13-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 THITH_09050 3b852a4089fa59072003f81547604e60 718 Pfam PF11842 Domain of unknown function (DUF3362) 587 694 1.3E-44 T 13-10-2018 IPR024560 Uncharacterised protein family UPF0313, C-terminal THITH_05640 c7033ea408ddd6099f50d034d6516429 107 SUPERFAMILY SSF47413 46 98 1.04E-5 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 THITH_17445 985aaa516228ddd4120dddbb4ca44e58 153 Gene3D G3DSA:3.50.80.10 1 145 2.9E-49 T 13-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily THITH_17445 985aaa516228ddd4120dddbb4ca44e58 153 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 31.318 T 13-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 THITH_17445 985aaa516228ddd4120dddbb4ca44e58 153 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 3 143 5.0E-48 T 13-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 THITH_17445 985aaa516228ddd4120dddbb4ca44e58 153 SUPERFAMILY SSF69500 2 144 1.83E-48 T 13-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily THITH_17445 985aaa516228ddd4120dddbb4ca44e58 153 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 2 145 2.7E-49 T 13-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 THITH_10635 8fc44df6323ab59a3712f9325c5d2c6b 109 Pfam PF08850 Domain of unknown function (DUF1820) 7 100 4.3E-40 T 13-10-2018 IPR014949 Protein of unknown function DUF1820 THITH_09530 8069cce6ac63538488ea42287bd9f4d6 273 SUPERFAMILY SSF55174 4 92 4.86E-16 T 13-10-2018 THITH_09530 8069cce6ac63538488ea42287bd9f4d6 273 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 102 116 - T 13-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 THITH_09530 8069cce6ac63538488ea42287bd9f4d6 273 Pfam PF00849 RNA pseudouridylate synthase 64 181 1.5E-13 T 13-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_09530 8069cce6ac63538488ea42287bd9f4d6 273 Pfam PF01479 S4 domain 3 48 4.4E-11 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_09530 8069cce6ac63538488ea42287bd9f4d6 273 Gene3D G3DSA:3.30.70.580 65 225 7.0E-48 T 13-10-2018 THITH_09530 8069cce6ac63538488ea42287bd9f4d6 273 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 68 228 2.2E-50 T 13-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 THITH_09530 8069cce6ac63538488ea42287bd9f4d6 273 SUPERFAMILY SSF55120 62 233 2.37E-40 T 13-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 THITH_09530 8069cce6ac63538488ea42287bd9f4d6 273 Gene3D G3DSA:3.10.290.10 1 57 1.2E-18 T 13-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 THITH_09530 8069cce6ac63538488ea42287bd9f4d6 273 SMART SM00363 3 59 1.3E-8 T 13-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_09530 8069cce6ac63538488ea42287bd9f4d6 273 Gene3D G3DSA:3.30.70.1560 126 216 7.0E-48 T 13-10-2018 THITH_01010 bee3e58338c2c878e9d71f17f9f78cac 287 Gene3D G3DSA:1.10.3720.10 70 283 1.6E-16 T 13-10-2018 IPR035906 MetI-like superfamily THITH_01010 bee3e58338c2c878e9d71f17f9f78cac 287 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 282 7.0E-18 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THITH_01010 bee3e58338c2c878e9d71f17f9f78cac 287 SUPERFAMILY SSF161098 76 261 9.42E-22 T 13-10-2018 IPR035906 MetI-like superfamily THITH_16995 117c2b00073aa13e87dcf036abde3dec 156 Pfam PF00430 ATP synthase B/B' CF(0) 6 136 3.5E-33 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 THITH_16995 117c2b00073aa13e87dcf036abde3dec 156 Hamap MF_01398 ATP synthase subunit b [atpF]. 1 138 12.924 T 13-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 THITH_16995 117c2b00073aa13e87dcf036abde3dec 156 Gene3D G3DSA:1.20.5.620 62 122 2.6E-14 T 13-10-2018 THITH_16995 117c2b00073aa13e87dcf036abde3dec 156 SUPERFAMILY SSF81573 63 121 6.02E-13 T 13-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily THITH_16995 117c2b00073aa13e87dcf036abde3dec 156 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 10 154 6.3E-47 T 13-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 THITH_12505 ba9e29758b106480dc4f7dcaae6cf245 268 Pfam PF08241 Methyltransferase domain 78 169 4.5E-14 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 THITH_12505 ba9e29758b106480dc4f7dcaae6cf245 268 Gene3D G3DSA:3.40.50.150 57 264 1.5E-22 T 13-10-2018 THITH_12505 ba9e29758b106480dc4f7dcaae6cf245 268 SUPERFAMILY SSF53335 51 249 5.93E-26 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_07455 69887b00932097a63fc612dbf661b501 240 SMART SM00382 27 221 1.7E-8 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_07455 69887b00932097a63fc612dbf661b501 240 Pfam PF00005 ABC transporter 19 168 8.4E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_07455 69887b00932097a63fc612dbf661b501 240 Gene3D G3DSA:3.40.50.300 2 224 1.5E-62 T 13-10-2018 THITH_07455 69887b00932097a63fc612dbf661b501 240 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_07455 69887b00932097a63fc612dbf661b501 240 SUPERFAMILY SSF52540 2 219 6.99E-56 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_15760 e1765c3a42c5a4688ee7582037aecb2a 239 SUPERFAMILY SSF53448 2 218 1.8E-47 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_15760 e1765c3a42c5a4688ee7582037aecb2a 239 Pfam PF00483 Nucleotidyl transferase 3 115 5.8E-17 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 THITH_15760 e1765c3a42c5a4688ee7582037aecb2a 239 Gene3D G3DSA:3.90.550.10 1 222 1.6E-50 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_05580 289fec2359759ac50b2e4544368f1d30 74 Pfam PF05509 TraY domain 4 49 4.0E-9 T 13-10-2018 IPR008876 Relaxosome protein TraY GO:0000746|GO:0003677 THITH_05580 289fec2359759ac50b2e4544368f1d30 74 SUPERFAMILY SSF47598 2 41 9.85E-11 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 THITH_06380 5a3d7191826332403d1a6d5d1a0fff29 456 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 50 302 2.5E-40 T 13-10-2018 IPR017039 Virulence factor BrkB THITH_06380 5a3d7191826332403d1a6d5d1a0fff29 456 Gene3D G3DSA:1.10.10.10 315 453 1.5E-7 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_06380 5a3d7191826332403d1a6d5d1a0fff29 456 SUPERFAMILY SSF46785 325 443 2.36E-6 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_06380 5a3d7191826332403d1a6d5d1a0fff29 456 Pfam PF03631 Virulence factor BrkB 54 304 1.4E-48 T 13-10-2018 IPR017039 Virulence factor BrkB THITH_17225 1898a91b4b8b1d4b83fd50eaf04fec32 298 Pfam PF00294 pfkB family carbohydrate kinase 27 284 5.2E-37 T 13-10-2018 IPR011611 Carbohydrate kinase PfkB THITH_17225 1898a91b4b8b1d4b83fd50eaf04fec32 298 Gene3D G3DSA:3.40.1190.20 8 291 1.6E-68 T 13-10-2018 IPR029056 Ribokinase-like THITH_17225 1898a91b4b8b1d4b83fd50eaf04fec32 298 SUPERFAMILY SSF53613 10 286 9.2E-52 T 13-10-2018 IPR029056 Ribokinase-like THITH_17225 1898a91b4b8b1d4b83fd50eaf04fec32 298 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 28 52 - T 13-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 THITH_10050 b549181d0fb3266d1f348037eb007ecb 321 Gene3D G3DSA:3.40.50.10320 23 223 2.5E-45 T 13-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 THITH_10050 b549181d0fb3266d1f348037eb007ecb 321 Pfam PF02585 GlcNAc-PI de-N-acetylase 24 143 2.8E-24 T 13-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 THITH_10050 b549181d0fb3266d1f348037eb007ecb 321 SUPERFAMILY SSF102588 23 219 1.83E-40 T 13-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 THITH_13870 776c07250533e73ecf45dad118c043b2 221 Gene3D G3DSA:2.160.10.10 94 202 1.8E-26 T 13-10-2018 THITH_13870 776c07250533e73ecf45dad118c043b2 221 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 3 203 9.0E-50 T 13-10-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like THITH_13870 776c07250533e73ecf45dad118c043b2 221 SUPERFAMILY SSF51161 4 203 3.88E-34 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily THITH_13870 776c07250533e73ecf45dad118c043b2 221 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 95 120 0.0019 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_13870 776c07250533e73ecf45dad118c043b2 221 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 159 192 1.9E-5 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_13870 776c07250533e73ecf45dad118c043b2 221 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 125 158 2.3E-7 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_02275 6110b004a167746fc82f5d199345c970 192 SUPERFAMILY SSF54523 11 103 9.42E-15 T 13-10-2018 THITH_02275 6110b004a167746fc82f5d199345c970 192 Gene3D G3DSA:3.30.700.10 11 185 1.5E-12 T 13-10-2018 THITH_02275 6110b004a167746fc82f5d199345c970 192 Pfam PF12019 Type II transport protein GspH 45 187 5.1E-6 T 13-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 THITH_02645 68a3745dc4fe453c1b130f1fc821780e 102 TIGRFAM TIGR04535 ferrit_encaps: ferritin-like protein 6 96 3.7E-40 T 13-10-2018 IPR030907 Ferritin-like protein THITH_02645 68a3745dc4fe453c1b130f1fc821780e 102 SUPERFAMILY SSF47240 5 90 1.59E-24 T 13-10-2018 IPR009078 Ferritin-like superfamily THITH_12835 9d7a4128e62489ac44fad6fa8b5ca704 624 SMART SM00116 172 220 4.5E-9 T 13-10-2018 IPR000644 CBS domain THITH_12835 9d7a4128e62489ac44fad6fa8b5ca704 624 SMART SM00116 237 284 1.5 T 13-10-2018 IPR000644 CBS domain THITH_12835 9d7a4128e62489ac44fad6fa8b5ca704 624 SUPERFAMILY SSF54631 166 280 7.07E-26 T 13-10-2018 THITH_12835 9d7a4128e62489ac44fad6fa8b5ca704 624 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 484 622 2.0E-39 T 13-10-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding THITH_12835 9d7a4128e62489ac44fad6fa8b5ca704 624 SUPERFAMILY SSF51206 10 145 9.3E-17 T 13-10-2018 IPR018490 Cyclic nucleotide-binding-like THITH_12835 9d7a4128e62489ac44fad6fa8b5ca704 624 Gene3D G3DSA:3.10.580.10 160 289 2.0E-30 T 13-10-2018 THITH_12835 9d7a4128e62489ac44fad6fa8b5ca704 624 Pfam PF00571 CBS domain 170 218 6.0E-12 T 13-10-2018 IPR000644 CBS domain THITH_12835 9d7a4128e62489ac44fad6fa8b5ca704 624 Pfam PF00571 CBS domain 231 280 4.1E-5 T 13-10-2018 IPR000644 CBS domain THITH_12835 9d7a4128e62489ac44fad6fa8b5ca704 624 Pfam PF03445 Putative nucleotidyltransferase DUF294 309 447 4.2E-43 T 13-10-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 THITH_12835 9d7a4128e62489ac44fad6fa8b5ca704 624 Gene3D G3DSA:2.60.120.10 7 148 2.4E-14 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_12835 9d7a4128e62489ac44fad6fa8b5ca704 624 Pfam PF00027 Cyclic nucleotide-binding domain 36 122 2.9E-8 T 13-10-2018 IPR000595 Cyclic nucleotide-binding domain THITH_13510 0b85b56fd8ad57cbcbf3241e308a1a28 263 SMART SM00244 18 175 1.1E-63 T 13-10-2018 IPR001107 Band 7 domain THITH_13510 0b85b56fd8ad57cbcbf3241e308a1a28 263 PRINTS PR00721 Stomatin signature 127 150 7.1E-65 T 13-10-2018 IPR001972 Stomatin family GO:0016020 THITH_13510 0b85b56fd8ad57cbcbf3241e308a1a28 263 PRINTS PR00721 Stomatin signature 72 93 7.1E-65 T 13-10-2018 IPR001972 Stomatin family GO:0016020 THITH_13510 0b85b56fd8ad57cbcbf3241e308a1a28 263 PRINTS PR00721 Stomatin signature 151 169 7.1E-65 T 13-10-2018 IPR001972 Stomatin family GO:0016020 THITH_13510 0b85b56fd8ad57cbcbf3241e308a1a28 263 PRINTS PR00721 Stomatin signature 170 191 7.1E-65 T 13-10-2018 IPR001972 Stomatin family GO:0016020 THITH_13510 0b85b56fd8ad57cbcbf3241e308a1a28 263 PRINTS PR00721 Stomatin signature 195 218 7.1E-65 T 13-10-2018 IPR001972 Stomatin family GO:0016020 THITH_13510 0b85b56fd8ad57cbcbf3241e308a1a28 263 PRINTS PR00721 Stomatin signature 107 124 7.1E-65 T 13-10-2018 IPR001972 Stomatin family GO:0016020 THITH_13510 0b85b56fd8ad57cbcbf3241e308a1a28 263 PRINTS PR00721 Stomatin signature 25 47 7.1E-65 T 13-10-2018 IPR001972 Stomatin family GO:0016020 THITH_13510 0b85b56fd8ad57cbcbf3241e308a1a28 263 Pfam PF01145 SPFH domain / Band 7 family 23 191 6.2E-34 T 13-10-2018 IPR001107 Band 7 domain THITH_13510 0b85b56fd8ad57cbcbf3241e308a1a28 263 SUPERFAMILY SSF117892 49 182 6.93E-45 T 13-10-2018 IPR036013 Band 7/SPFH domain superfamily THITH_13510 0b85b56fd8ad57cbcbf3241e308a1a28 263 Gene3D G3DSA:3.30.479.30 46 177 4.0E-48 T 13-10-2018 THITH_03130 4d9cf40271226159c03eb28577e991ad 131 Gene3D G3DSA:3.10.450.40 6 129 7.3E-30 T 13-10-2018 THITH_03130 4d9cf40271226159c03eb28577e991ad 131 Pfam PF04965 Gene 25-like lysozyme 27 115 1.4E-19 T 13-10-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD THITH_03130 4d9cf40271226159c03eb28577e991ad 131 SUPERFAMILY SSF160719 25 127 5.49E-27 T 13-10-2018 THITH_07545 ce16a7831e8ca197b1e5da022ac009db 142 Gene3D G3DSA:3.10.580.10 1 131 4.0E-48 T 13-10-2018 THITH_07545 ce16a7831e8ca197b1e5da022ac009db 142 SMART SM00116 79 126 1.1E-10 T 13-10-2018 IPR000644 CBS domain THITH_07545 ce16a7831e8ca197b1e5da022ac009db 142 SMART SM00116 14 61 6.0E-9 T 13-10-2018 IPR000644 CBS domain THITH_07545 ce16a7831e8ca197b1e5da022ac009db 142 SUPERFAMILY SSF54631 3 140 5.68E-36 T 13-10-2018 THITH_07545 ce16a7831e8ca197b1e5da022ac009db 142 Pfam PF00571 CBS domain 13 59 4.5E-12 T 13-10-2018 IPR000644 CBS domain THITH_07545 ce16a7831e8ca197b1e5da022ac009db 142 Pfam PF00571 CBS domain 72 126 3.5E-12 T 13-10-2018 IPR000644 CBS domain THITH_06495 1ae1d74e174ac8875d88ac2b5f9e52ef 358 Pfam PF01075 Glycosyltransferase family 9 (heptosyltransferase) 230 324 1.4E-5 T 13-10-2018 IPR002201 Glycosyl transferase, family 9 GO:0016757 THITH_06495 1ae1d74e174ac8875d88ac2b5f9e52ef 358 Gene3D G3DSA:3.40.50.2000 8 148 9.1E-22 T 13-10-2018 THITH_06495 1ae1d74e174ac8875d88ac2b5f9e52ef 358 SUPERFAMILY SSF53756 8 352 2.83E-56 T 13-10-2018 THITH_06495 1ae1d74e174ac8875d88ac2b5f9e52ef 358 Gene3D G3DSA:3.40.50.2000 172 352 1.7E-16 T 13-10-2018 THITH_10440 f02457daea070a89237b7c96b8f00993 251 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 18 241 37.565 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 THITH_10440 f02457daea070a89237b7c96b8f00993 251 Gene3D G3DSA:3.40.1180.10 5 241 6.1E-86 T 13-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 THITH_10440 f02457daea070a89237b7c96b8f00993 251 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 19 240 7.1E-77 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 THITH_10440 f02457daea070a89237b7c96b8f00993 251 SUPERFAMILY SSF64005 16 236 1.1E-74 T 13-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 THITH_10440 f02457daea070a89237b7c96b8f00993 251 Pfam PF01255 Putative undecaprenyl diphosphate synthase 25 240 8.9E-75 T 13-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 THITH_10440 f02457daea070a89237b7c96b8f00993 251 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 186 203 - T 13-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 THITH_01500 2f0ce5e654f868311838192e9f308095 163 Gene3D G3DSA:3.30.70.640 1 159 3.0E-68 T 13-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_01500 2f0ce5e654f868311838192e9f308095 163 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 150 3.5E-65 T 13-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_01500 2f0ce5e654f868311838192e9f308095 163 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 2 156 35.661 T 13-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_01500 2f0ce5e654f868311838192e9f308095 163 Pfam PF01967 MoaC family 15 148 2.5E-55 T 13-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_01500 2f0ce5e654f868311838192e9f308095 163 SUPERFAMILY SSF55040 11 153 3.01E-59 T 13-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_02635 28553833ddbc778bd0d044504a77626d 139 Pfam PF02915 Rubrerythrin 10 133 1.5E-28 T 13-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 THITH_02635 28553833ddbc778bd0d044504a77626d 139 Gene3D G3DSA:1.20.1260.10 1 138 3.7E-55 T 13-10-2018 IPR012347 Ferritin-like THITH_02635 28553833ddbc778bd0d044504a77626d 139 SUPERFAMILY SSF47240 3 138 3.2E-42 T 13-10-2018 IPR009078 Ferritin-like superfamily THITH_17105 98838a120ff8d5cedf57c8b9a7b9c9fa 154 Pfam PF00588 SpoU rRNA Methylase family 2 141 1.9E-29 T 13-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 THITH_17105 98838a120ff8d5cedf57c8b9a7b9c9fa 154 SUPERFAMILY SSF75217 1 152 7.19E-40 T 13-10-2018 IPR029028 Alpha/beta knot methyltransferases THITH_17105 98838a120ff8d5cedf57c8b9a7b9c9fa 154 PIRSF PIRSF029256 1 154 2.2E-60 T 13-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 THITH_17105 98838a120ff8d5cedf57c8b9a7b9c9fa 154 Gene3D G3DSA:3.40.1280.10 1 154 1.4E-61 T 13-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal THITH_17105 98838a120ff8d5cedf57c8b9a7b9c9fa 154 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 2 151 31.697 T 13-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 THITH_03405 e3f486e09ddfd985f48b3086c18a4639 96 Gene3D G3DSA:3.30.460.10 4 96 1.0E-17 T 13-10-2018 THITH_03405 e3f486e09ddfd985f48b3086c18a4639 96 SUPERFAMILY SSF81301 6 95 1.64E-16 T 13-10-2018 THITH_03405 e3f486e09ddfd985f48b3086c18a4639 96 Pfam PF01909 Nucleotidyltransferase domain 27 92 2.3E-7 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THITH_08020 1b6df98b790a28e432f1b5bf232d8652 348 Gene3D G3DSA:3.40.50.2000 153 325 1.0E-53 T 13-10-2018 THITH_08020 1b6df98b790a28e432f1b5bf232d8652 348 Pfam PF00534 Glycosyl transferases group 1 167 323 9.9E-34 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 THITH_08020 1b6df98b790a28e432f1b5bf232d8652 348 Gene3D G3DSA:3.40.50.2000 73 339 1.0E-53 T 13-10-2018 THITH_08020 1b6df98b790a28e432f1b5bf232d8652 348 SUPERFAMILY SSF53756 8 342 2.47E-64 T 13-10-2018 THITH_15425 3dc7c55da5ddaedd47857a4874845209 219 Pfam PF07883 Cupin domain 139 205 3.2E-12 T 13-10-2018 IPR013096 Cupin 2, conserved barrel THITH_15425 3dc7c55da5ddaedd47857a4874845209 219 SUPERFAMILY SSF51182 104 210 1.76E-19 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily THITH_15425 3dc7c55da5ddaedd47857a4874845209 219 Gene3D G3DSA:2.60.120.10 102 219 7.2E-18 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_04960 c94da6f550c88785ed5f2f911985178b 221 Pfam PF09335 SNARE associated Golgi protein 61 177 1.1E-22 T 13-10-2018 IPR032816 SNARE associated Golgi protein THITH_07285 c2114ede047eeab8b694fac9c02445d2 482 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 15 473 6.3E-195 T 13-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 THITH_07285 c2114ede047eeab8b694fac9c02445d2 482 Pfam PF01458 Uncharacterized protein family (UPF0051) 220 453 1.5E-70 T 13-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 THITH_07285 c2114ede047eeab8b694fac9c02445d2 482 SUPERFAMILY SSF101960 36 479 1.2E-142 T 13-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily THITH_04100 3a7a61e45388cb2f4bdd4642694a98af 247 Pfam PF11911 Protein of unknown function (DUF3429) 103 238 7.9E-28 T 13-10-2018 IPR021836 Protein of unknown function DUF3429 THITH_06265 b2ef3cd8fdf84b9a0016a4ac9c0ef2d4 274 Gene3D G3DSA:3.60.21.10 1 271 4.3E-74 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like THITH_06265 b2ef3cd8fdf84b9a0016a4ac9c0ef2d4 274 SUPERFAMILY SSF56300 1 258 1.58E-50 T 13-10-2018 THITH_06265 b2ef3cd8fdf84b9a0016a4ac9c0ef2d4 274 Hamap MF_00199 Bis(5'-nucleosyl)-tetraphosphatase, symmetrical [apaH]. 1 271 44.706 T 13-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 THITH_06265 b2ef3cd8fdf84b9a0016a4ac9c0ef2d4 274 PIRSF PIRSF000903 1 273 3.9E-103 T 13-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 THITH_06265 b2ef3cd8fdf84b9a0016a4ac9c0ef2d4 274 TIGRFAM TIGR00668 apaH: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) 1 259 2.7E-93 T 13-10-2018 IPR004617 Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) GO:0008803 KEGG: 00230+3.6.1.41 THITH_06265 b2ef3cd8fdf84b9a0016a4ac9c0ef2d4 274 Pfam PF00149 Calcineurin-like phosphoesterase 2 128 2.6E-11 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THITH_10245 d9adb53dab08ee934734fa1ae46dd4af 191 Gene3D G3DSA:3.30.70.260 2 81 3.7E-17 T 13-10-2018 THITH_10245 d9adb53dab08ee934734fa1ae46dd4af 191 Gene3D G3DSA:3.30.70.260 87 176 1.3E-22 T 13-10-2018 THITH_10245 d9adb53dab08ee934734fa1ae46dd4af 191 SUPERFAMILY SSF55021 90 170 1.53E-13 T 13-10-2018 THITH_10245 d9adb53dab08ee934734fa1ae46dd4af 191 SUPERFAMILY SSF55021 3 67 3.13E-9 T 13-10-2018 THITH_10245 d9adb53dab08ee934734fa1ae46dd4af 191 PIRSF PIRSF028103 1 178 3.3E-43 T 13-10-2018 IPR016867 Glycine cleavage system transcriptional repressor GO:0006355 THITH_10245 d9adb53dab08ee934734fa1ae46dd4af 191 Pfam PF13740 ACT domain 5 70 6.8E-15 T 13-10-2018 THITH_08720 6d533bac464ba5171d2a13da23c69aca 342 Pfam PF02618 YceG-like family 43 325 2.0E-79 T 13-10-2018 IPR003770 Endolytic murein transglycosylase THITH_08720 6d533bac464ba5171d2a13da23c69aca 342 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 9 328 2.0E-70 T 13-10-2018 IPR003770 Endolytic murein transglycosylase THITH_08720 6d533bac464ba5171d2a13da23c69aca 342 Gene3D G3DSA:1.10.8.1150 39 111 1.9E-5 T 13-10-2018 THITH_08720 6d533bac464ba5171d2a13da23c69aca 342 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 4 330 32.663 T 13-10-2018 IPR003770 Endolytic murein transglycosylase THITH_08720 6d533bac464ba5171d2a13da23c69aca 342 Gene3D G3DSA:3.30.160.60 302 331 1.9E-5 T 13-10-2018 THITH_06025 733f83c053669ae0cd13bb7a0eac3def 395 Gene3D G3DSA:3.40.50.720 8 369 1.2E-138 T 13-10-2018 THITH_06025 733f83c053669ae0cd13bb7a0eac3def 395 Pfam PF02719 Polysaccharide biosynthesis protein 35 272 2.1E-37 T 13-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain THITH_06025 733f83c053669ae0cd13bb7a0eac3def 395 Gene3D G3DSA:3.90.25.40 200 310 1.2E-138 T 13-10-2018 THITH_06025 733f83c053669ae0cd13bb7a0eac3def 395 SUPERFAMILY SSF51735 32 288 9.95E-28 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_12445 f6f6c9d6bab68abf4d77928cb1519a50 448 Gene3D G3DSA:3.30.470.20 112 437 2.9E-26 T 13-10-2018 THITH_12445 f6f6c9d6bab68abf4d77928cb1519a50 448 SUPERFAMILY SSF56059 142 356 9.03E-28 T 13-10-2018 THITH_12445 f6f6c9d6bab68abf4d77928cb1519a50 448 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 257 332 4.6E-7 T 13-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 THITH_11935 326bef0b96725eabf9545a7f0ede5abc 265 PIRSF PIRSF000441 1 236 2.6E-87 T 13-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 THITH_11935 326bef0b96725eabf9545a7f0ede5abc 265 SUPERFAMILY SSF51161 2 175 3.6E-56 T 13-10-2018 IPR011004 Trimeric LpxA-like superfamily THITH_11935 326bef0b96725eabf9545a7f0ede5abc 265 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 13-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 THITH_11935 326bef0b96725eabf9545a7f0ede5abc 265 Gene3D G3DSA:1.10.3130.10 1 66 1.3E-22 T 13-10-2018 THITH_11935 326bef0b96725eabf9545a7f0ede5abc 265 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 72 108 2.1E-4 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_11935 326bef0b96725eabf9545a7f0ede5abc 265 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 120 151 2.9E-7 T 13-10-2018 IPR001451 Hexapeptide repeat THITH_11935 326bef0b96725eabf9545a7f0ede5abc 265 Gene3D G3DSA:2.160.10.10 67 188 6.6E-38 T 13-10-2018 THITH_11935 326bef0b96725eabf9545a7f0ede5abc 265 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 166 2.4E-76 T 13-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 THITH_12235 b19475a648a984807745b4ad0e5c735a 76 SUPERFAMILY SSF52833 1 69 4.25E-19 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_12235 b19475a648a984807745b4ad0e5c735a 76 TIGRFAM TIGR02190 GlrX-dom: glutaredoxin-family domain 1 67 1.1E-30 T 13-10-2018 IPR011906 Glutaredoxin domain KEGG: 00480+1.11.1.15 THITH_12235 b19475a648a984807745b4ad0e5c735a 76 Pfam PF00462 Glutaredoxin 1 57 4.6E-17 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 THITH_12235 b19475a648a984807745b4ad0e5c735a 76 ProSitePatterns PS00195 Glutaredoxin active site. 1 17 - T 13-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 THITH_12235 b19475a648a984807745b4ad0e5c735a 76 Gene3D G3DSA:3.40.30.10 1 67 4.7E-22 T 13-10-2018 THITH_07765 3cdc0d7ec572c600241021fd10c3f3cb 551 SUPERFAMILY SSF46626 368 414 6.6E-5 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_12075 f02aac56f12605e8e64ba65399fc35e6 334 SUPERFAMILY SSF52540 51 163 8.1E-14 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_12075 f02aac56f12605e8e64ba65399fc35e6 334 Hamap MF_00409 Tetraacyldisaccharide 4'-kinase [lpxK]. 1 329 36.531 T 13-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 THITH_12075 f02aac56f12605e8e64ba65399fc35e6 334 Pfam PF02606 Tetraacyldisaccharide-1-P 4'-kinase 18 324 5.8E-99 T 13-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 THITH_12075 f02aac56f12605e8e64ba65399fc35e6 334 TIGRFAM TIGR00682 lpxK: tetraacyldisaccharide 4'-kinase 23 324 5.0E-70 T 13-10-2018 IPR003758 Tetraacyldisaccharide 4'-kinase GO:0005524|GO:0009029|GO:0009245 KEGG: 00540+2.7.1.130 THITH_06690 6949bae83440a1e3aa63bf5af4f0c9ab 101 Pfam PF08895 Domain of unknown function (DUF1840) 1 99 2.3E-29 T 13-10-2018 IPR014991 Protein of unknown function DUF1840 THITH_01340 9c7a82b4d90c8ad018f1bb35c5a027f3 328 SMART SM00729 15 221 1.0E-12 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THITH_01340 9c7a82b4d90c8ad018f1bb35c5a027f3 328 SUPERFAMILY SSF102114 6 280 9.94E-74 T 13-10-2018 THITH_01340 9c7a82b4d90c8ad018f1bb35c5a027f3 328 Gene3D G3DSA:3.20.20.70 3 328 2.4E-88 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_01340 9c7a82b4d90c8ad018f1bb35c5a027f3 328 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 6 328 3.3E-111 T 13-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_01340 9c7a82b4d90c8ad018f1bb35c5a027f3 328 Pfam PF13353 4Fe-4S single cluster domain 22 85 1.3E-6 T 13-10-2018 THITH_01340 9c7a82b4d90c8ad018f1bb35c5a027f3 328 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 21 32 - T 13-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_01340 9c7a82b4d90c8ad018f1bb35c5a027f3 328 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 6 328 38.409 T 13-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_01340 9c7a82b4d90c8ad018f1bb35c5a027f3 328 Pfam PF06463 Molybdenum Cofactor Synthesis C 186 312 2.1E-35 T 13-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_01340 9c7a82b4d90c8ad018f1bb35c5a027f3 328 Pfam PF04055 Radical SAM superfamily 19 179 3.2E-27 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THITH_12405 ce103b28fe88a6e52f2ad02218d96b75 442 Gene3D G3DSA:1.25.40.10 11 260 2.8E-10 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_12405 ce103b28fe88a6e52f2ad02218d96b75 442 SUPERFAMILY SSF48452 155 256 3.9E-9 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_16225 c722cb5b00bc80d5f25b18543351a870 632 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_16225 c722cb5b00bc80d5f25b18543351a870 632 SUPERFAMILY SSF52540 2 239 3.67E-44 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16225 c722cb5b00bc80d5f25b18543351a870 632 ProSitePatterns PS00211 ABC transporters family signature. 428 442 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_16225 c722cb5b00bc80d5f25b18543351a870 632 SUPERFAMILY SSF52540 294 512 4.24E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16225 c722cb5b00bc80d5f25b18543351a870 632 Pfam PF00005 ABC transporter 20 175 1.7E-22 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_16225 c722cb5b00bc80d5f25b18543351a870 632 SMART SM00382 26 227 3.5E-6 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_16225 c722cb5b00bc80d5f25b18543351a870 632 SMART SM00382 334 500 1.8E-13 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_16225 c722cb5b00bc80d5f25b18543351a870 632 Gene3D G3DSA:3.40.50.300 1 255 8.7E-56 T 13-10-2018 THITH_16225 c722cb5b00bc80d5f25b18543351a870 632 Gene3D G3DSA:3.40.50.300 272 525 3.3E-54 T 13-10-2018 THITH_16225 c722cb5b00bc80d5f25b18543351a870 632 Pfam PF00005 ABC transporter 327 456 2.4E-20 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_16225 c722cb5b00bc80d5f25b18543351a870 632 Pfam PF12848 ABC transporter 214 289 5.4E-20 T 13-10-2018 IPR032781 ABC-transporter extension domain THITH_01595 391a8d6fff30ff3a375c66c9531b5df6 257 Gene3D G3DSA:1.10.10.10 8 40 7.3E-7 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_05255 98dce1924507b791cbf4baa39f268378 140 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 13 133 17.194 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 THITH_05255 98dce1924507b791cbf4baa39f268378 140 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 15 128 1.1E-20 T 13-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 THITH_01770 3a69035024401605e4f1cf5476b740a0 1076 SUPERFAMILY SSF51998 103 1020 9.84E-129 T 13-10-2018 THITH_01770 3a69035024401605e4f1cf5476b740a0 1076 Gene3D G3DSA:2.170.16.10 331 439 1.5E-14 T 13-10-2018 THITH_01770 3a69035024401605e4f1cf5476b740a0 1076 Gene3D G3DSA:3.20.70.20 6 330 2.9E-69 T 13-10-2018 THITH_01770 3a69035024401605e4f1cf5476b740a0 1076 TIGRFAM TIGR01445 intein_Nterm: intein N-terminal splicing region 326 406 7.7E-10 T 13-10-2018 IPR006141 Intein N-terminal splicing region GO:0016539 Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THITH_01770 3a69035024401605e4f1cf5476b740a0 1076 PRINTS PR00379 Intein signature 545 557 4.4E-11 T 13-10-2018 IPR006142 Intein GO:0016539 THITH_01770 3a69035024401605e4f1cf5476b740a0 1076 PRINTS PR00379 Intein signature 660 677 4.4E-11 T 13-10-2018 IPR006142 Intein GO:0016539 THITH_01770 3a69035024401605e4f1cf5476b740a0 1076 PRINTS PR00379 Intein signature 393 406 4.4E-11 T 13-10-2018 IPR006142 Intein GO:0016539 THITH_01770 3a69035024401605e4f1cf5476b740a0 1076 PRINTS PR00379 Intein signature 577 592 4.4E-11 T 13-10-2018 IPR006142 Intein GO:0016539 THITH_01770 3a69035024401605e4f1cf5476b740a0 1076 PRINTS PR00379 Intein signature 439 451 4.4E-11 T 13-10-2018 IPR006142 Intein GO:0016539 THITH_01770 3a69035024401605e4f1cf5476b740a0 1076 Gene3D G3DSA:3.20.70.20 674 1027 3.3E-88 T 13-10-2018 THITH_01770 3a69035024401605e4f1cf5476b740a0 1076 SMART SM00306 324 426 4.6E-12 T 13-10-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THITH_01770 3a69035024401605e4f1cf5476b740a0 1076 SUPERFAMILY SSF51294 325 681 2.94E-24 T 13-10-2018 IPR036844 Hint domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 THITH_01770 3a69035024401605e4f1cf5476b740a0 1076 Pfam PF14528 LAGLIDADG-like domain 545 623 2.9E-13 T 13-10-2018 IPR004860 Homing endonuclease, LAGLIDADG GO:0004519 THITH_01770 3a69035024401605e4f1cf5476b740a0 1076 SUPERFAMILY SSF55608 531 631 1.76E-10 T 13-10-2018 IPR027434 Homing endonuclease THITH_01770 3a69035024401605e4f1cf5476b740a0 1076 Pfam PF02867 Ribonucleotide reductase, barrel domain 104 1012 7.1E-137 T 13-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 THITH_01770 3a69035024401605e4f1cf5476b740a0 1076 Gene3D G3DSA:3.10.28.10 440 613 3.4E-17 T 13-10-2018 IPR027434 Homing endonuclease THITH_06355 a027aeec4cbc3e68f606d8d31b5fbb7c 79 SUPERFAMILY SSF82657 3 77 7.19E-21 T 13-10-2018 IPR036065 BolA-like superfamily THITH_06355 a027aeec4cbc3e68f606d8d31b5fbb7c 79 PIRSF PIRSF003113 1 79 5.6E-19 T 13-10-2018 IPR002634 BolA protein THITH_06355 a027aeec4cbc3e68f606d8d31b5fbb7c 79 Gene3D G3DSA:3.30.300.90 1 79 2.0E-24 T 13-10-2018 THITH_06355 a027aeec4cbc3e68f606d8d31b5fbb7c 79 Pfam PF01722 BolA-like protein 22 75 7.2E-16 T 13-10-2018 IPR002634 BolA protein THITH_00130 d1e6c02addc639d061e934e903a99bbd 403 Gene3D G3DSA:1.20.81.30 54 171 4.4E-29 T 13-10-2018 THITH_00130 d1e6c02addc639d061e934e903a99bbd 403 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 164 192 - T 13-10-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 THITH_00130 d1e6c02addc639d061e934e903a99bbd 403 Pfam PF00482 Type II secretion system (T2SS), protein F 70 192 7.5E-31 T 13-10-2018 IPR018076 Type II secretion system F domain THITH_00130 d1e6c02addc639d061e934e903a99bbd 403 Pfam PF00482 Type II secretion system (T2SS), protein F 272 394 1.0E-27 T 13-10-2018 IPR018076 Type II secretion system F domain THITH_00130 d1e6c02addc639d061e934e903a99bbd 403 Gene3D G3DSA:1.20.81.30 255 366 2.1E-28 T 13-10-2018 THITH_00130 d1e6c02addc639d061e934e903a99bbd 403 TIGRFAM TIGR02120 GspF: type II secretion system protein F 4 402 6.9E-156 T 13-10-2018 IPR011850 General secretion pathway protein F GO:0008565|GO:0015627|GO:0015628 THITH_00130 d1e6c02addc639d061e934e903a99bbd 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 65 77 1.3E-33 T 13-10-2018 IPR003004 GspF/PilC family THITH_00130 d1e6c02addc639d061e934e903a99bbd 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 164 192 1.3E-33 T 13-10-2018 IPR003004 GspF/PilC family THITH_00130 d1e6c02addc639d061e934e903a99bbd 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 367 381 1.3E-33 T 13-10-2018 IPR003004 GspF/PilC family THITH_00130 d1e6c02addc639d061e934e903a99bbd 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 383 402 1.3E-33 T 13-10-2018 IPR003004 GspF/PilC family THITH_09255 5d2f08643bd56d4cae8781d501f377bf 318 Pfam PF10040 CRISPR-associated endoribonuclease Cas6 189 312 2.5E-13 T 13-10-2018 IPR019267 CRISPR-associated protein Cas6, C-terminal THITH_09255 5d2f08643bd56d4cae8781d501f377bf 318 Gene3D G3DSA:3.30.70.1900 180 315 2.0E-8 T 13-10-2018 THITH_14835 ee054308c0c5e508cd2db6649cddb61b 273 Pfam PF01026 TatD related DNase 4 260 4.1E-64 T 13-10-2018 IPR001130 TatD family GO:0016788 THITH_14835 ee054308c0c5e508cd2db6649cddb61b 273 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 192 208 - T 13-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 THITH_14835 ee054308c0c5e508cd2db6649cddb61b 273 Gene3D G3DSA:3.20.20.140 3 264 2.0E-90 T 13-10-2018 THITH_14835 ee054308c0c5e508cd2db6649cddb61b 273 PIRSF PIRSF005902 1 264 5.7E-70 T 13-10-2018 IPR001130 TatD family GO:0016788 THITH_14835 ee054308c0c5e508cd2db6649cddb61b 273 SUPERFAMILY SSF51556 3 262 4.54E-78 T 13-10-2018 IPR032466 Metal-dependent hydrolase THITH_03885 afe76639750492945c32a96edb53d348 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 13-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 THITH_03885 afe76639750492945c32a96edb53d348 130 SUPERFAMILY SSF54211 6 130 4.55E-46 T 13-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold THITH_03885 afe76639750492945c32a96edb53d348 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 32.446 T 13-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid THITH_03885 afe76639750492945c32a96edb53d348 130 Gene3D G3DSA:3.30.230.10 1 130 7.0E-51 T 13-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup THITH_03885 afe76639750492945c32a96edb53d348 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 1.5E-44 T 13-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 THITH_15040 29756ac2697df1f6bb0d1c23d4050656 74 ProDom PD028561 MEMBRANE IMMUNITY SUPERINFECTION GP66 PROTEIN IMM GP75 IMM RB69 INTEGRAL 14 53 2.0E-6 T 13-10-2018 IPR016410 Bacteriophage-associated immunity protein THITH_15040 29756ac2697df1f6bb0d1c23d4050656 74 Pfam PF14373 Superinfection immunity protein 13 54 8.9E-17 T 13-10-2018 IPR016410 Bacteriophage-associated immunity protein THITH_07485 b56f492012b1338c6342660f8b4e1558 69 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 1 67 7.2E-20 T 13-10-2018 IPR003746 Protein of unknown function DUF167 THITH_07485 b56f492012b1338c6342660f8b4e1558 69 SUPERFAMILY SSF69786 1 69 5.1E-19 T 13-10-2018 IPR036591 YggU-like superfamily THITH_07485 b56f492012b1338c6342660f8b4e1558 69 Gene3D G3DSA:3.30.1200.10 1 69 1.6E-19 T 13-10-2018 IPR036591 YggU-like superfamily THITH_07485 b56f492012b1338c6342660f8b4e1558 69 SMART SM01152 1 69 1.2E-15 T 13-10-2018 IPR003746 Protein of unknown function DUF167 THITH_15635 a187bdf6b9e567c103457ea529698880 290 Hamap MF_01635 4-hydroxybenzoate octaprenyltransferase [ubiA]. 2 286 28.573 T 13-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 THITH_15635 a187bdf6b9e567c103457ea529698880 290 Pfam PF01040 UbiA prenyltransferase family 25 267 1.9E-61 T 13-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 THITH_15635 a187bdf6b9e567c103457ea529698880 290 TIGRFAM TIGR01474 ubiA_proteo: 4-hydroxybenzoate polyprenyl transferase 8 285 1.4E-97 T 13-10-2018 IPR006370 4-hydroxybenzoate polyprenyltransferase-like GO:0004659|GO:0016021 Reactome: R-HSA-1268020|Reactome: R-HSA-2142789 THITH_15635 a187bdf6b9e567c103457ea529698880 290 Gene3D G3DSA:1.10.357.140 22 168 1.9E-41 T 13-10-2018 THITH_15635 a187bdf6b9e567c103457ea529698880 290 Gene3D G3DSA:1.20.120.1780 169 288 6.4E-13 T 13-10-2018 THITH_15635 a187bdf6b9e567c103457ea529698880 290 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 64 86 - T 13-10-2018 IPR030470 UbiA prenyltransferase conserved site THITH_07090 334bc52eb52abe3e1c4062de3406437a 103 Pfam PF04977 Septum formation initiator 12 88 8.3E-23 T 13-10-2018 IPR007060 Septum formation initiator FtsL/DivIC THITH_07090 334bc52eb52abe3e1c4062de3406437a 103 Hamap MF_00599 Cell division protein FtsB [ftsB]. 1 90 31.853 T 13-10-2018 IPR023081 Cell division protein FtsB THITH_02725 157eb92222575a7f61b8a3889081126b 331 Gene3D G3DSA:3.90.226.10 97 293 8.2E-36 T 13-10-2018 THITH_02725 157eb92222575a7f61b8a3889081126b 331 Pfam PF08496 Peptidase family S49 N-terminal 2 150 1.4E-43 T 13-10-2018 IPR013703 Peptidase S49, N-terminal proteobacteria GO:0004252|GO:0005886 THITH_02725 157eb92222575a7f61b8a3889081126b 331 SUPERFAMILY SSF52096 90 291 5.18E-27 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THITH_02725 157eb92222575a7f61b8a3889081126b 331 Gene3D G3DSA:3.40.1750.20 194 258 8.2E-36 T 13-10-2018 THITH_02725 157eb92222575a7f61b8a3889081126b 331 Pfam PF01343 Peptidase family S49 154 301 6.8E-41 T 13-10-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 THITH_10080 dc10d5cce2592f7f04067c5f685b78c8 286 Pfam PF13852 Protein of unknown function (DUF4197) 84 283 6.5E-72 T 13-10-2018 IPR025245 Protein of unknown function DUF4197 THITH_14415 4eb1dc9b689b1b5dd0a84cd7e79f59c0 403 Gene3D G3DSA:3.60.70.12 9 273 8.0E-92 T 13-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 THITH_14415 4eb1dc9b689b1b5dd0a84cd7e79f59c0 403 Gene3D G3DSA:3.10.20.340 274 403 6.2E-40 T 13-10-2018 THITH_14415 4eb1dc9b689b1b5dd0a84cd7e79f59c0 403 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 14 403 1.9E-114 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 THITH_14415 4eb1dc9b689b1b5dd0a84cd7e79f59c0 403 Pfam PF01960 ArgJ family 20 403 6.0E-138 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 THITH_14415 4eb1dc9b689b1b5dd0a84cd7e79f59c0 403 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 403 143.843 T 13-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 THITH_14415 4eb1dc9b689b1b5dd0a84cd7e79f59c0 403 SUPERFAMILY SSF56266 14 400 2.88E-133 T 13-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 THITH_14415 4eb1dc9b689b1b5dd0a84cd7e79f59c0 403 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 26 403 2.0E-111 T 13-10-2018 THITH_00895 6895687483f0d71f6d56c1a4da24acf5 164 Pfam PF08447 PAS fold 55 136 2.5E-13 T 13-10-2018 IPR013655 PAS fold-3 GO:0005515 THITH_00895 6895687483f0d71f6d56c1a4da24acf5 164 Gene3D G3DSA:3.30.450.20 38 163 5.0E-24 T 13-10-2018 THITH_00895 6895687483f0d71f6d56c1a4da24acf5 164 SUPERFAMILY SSF55785 44 139 3.32E-25 T 13-10-2018 IPR035965 PAS domain superfamily THITH_00895 6895687483f0d71f6d56c1a4da24acf5 164 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 48 138 4.3E-13 T 13-10-2018 IPR000014 PAS domain THITH_11825 b92745a42d9afa87126330ff95a00f28 290 Pfam PF08238 Sel1 repeat 224 256 8.9E-4 T 13-10-2018 IPR006597 Sel1-like repeat THITH_11825 b92745a42d9afa87126330ff95a00f28 290 Pfam PF08238 Sel1 repeat 74 107 3.9E-8 T 13-10-2018 IPR006597 Sel1-like repeat THITH_11825 b92745a42d9afa87126330ff95a00f28 290 Pfam PF08238 Sel1 repeat 185 220 0.0024 T 13-10-2018 IPR006597 Sel1-like repeat THITH_11825 b92745a42d9afa87126330ff95a00f28 290 Pfam PF08238 Sel1 repeat 113 143 1.6E-5 T 13-10-2018 IPR006597 Sel1-like repeat THITH_11825 b92745a42d9afa87126330ff95a00f28 290 SMART SM00671 221 256 0.0016 T 13-10-2018 IPR006597 Sel1-like repeat THITH_11825 b92745a42d9afa87126330ff95a00f28 290 SMART SM00671 184 220 7.5E-4 T 13-10-2018 IPR006597 Sel1-like repeat THITH_11825 b92745a42d9afa87126330ff95a00f28 290 SMART SM00671 109 144 0.25 T 13-10-2018 IPR006597 Sel1-like repeat THITH_11825 b92745a42d9afa87126330ff95a00f28 290 SMART SM00671 73 108 1.2E-9 T 13-10-2018 IPR006597 Sel1-like repeat THITH_11825 b92745a42d9afa87126330ff95a00f28 290 Gene3D G3DSA:1.25.40.10 23 161 3.2E-26 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_11825 b92745a42d9afa87126330ff95a00f28 290 Gene3D G3DSA:1.25.40.10 162 289 5.2E-24 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_11825 b92745a42d9afa87126330ff95a00f28 290 SUPERFAMILY SSF81901 150 257 1.83E-14 T 13-10-2018 THITH_11825 b92745a42d9afa87126330ff95a00f28 290 SUPERFAMILY SSF81901 36 147 2.88E-22 T 13-10-2018 THITH_07270 337a013671f5a5ad286e9cbd7b3ce7b6 397 SUPERFAMILY SSF53383 2 395 2.04E-92 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_07270 337a013671f5a5ad286e9cbd7b3ce7b6 397 TIGRFAM TIGR03538 DapC_gpp: succinyldiaminopimelate transaminase 1 393 1.1E-178 T 13-10-2018 IPR019878 Succinyldiaminopimelate transaminase, DapC, beta/gammaproteobacteria GO:0009016|GO:0009089 THITH_07270 337a013671f5a5ad286e9cbd7b3ce7b6 397 Gene3D G3DSA:3.90.1150.10 13 382 6.2E-117 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_07270 337a013671f5a5ad286e9cbd7b3ce7b6 397 Gene3D G3DSA:3.40.640.10 43 290 6.2E-117 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_07270 337a013671f5a5ad286e9cbd7b3ce7b6 397 Pfam PF00155 Aminotransferase class I and II 32 374 6.2E-44 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THITH_00195 1b4092456c642b7920684b3d6c4e735c 136 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 2 120 1.8E-16 T 13-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component THITH_00195 1b4092456c642b7920684b3d6c4e735c 136 Pfam PF13470 PIN domain 2 115 1.2E-15 T 13-10-2018 IPR002716 PIN domain THITH_00195 1b4092456c642b7920684b3d6c4e735c 136 SUPERFAMILY SSF88723 2 121 2.35E-10 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_16330 f9b3e095c956d3d0bec8e969e5cea43c 271 Pfam PF13649 Methyltransferase domain 63 160 1.1E-14 T 13-10-2018 THITH_16330 f9b3e095c956d3d0bec8e969e5cea43c 271 Gene3D G3DSA:3.30.46.10 34 218 2.2E-62 T 13-10-2018 THITH_16330 f9b3e095c956d3d0bec8e969e5cea43c 271 PIRSF PIRSF000385 21 197 1.1E-30 T 13-10-2018 IPR014369 Glycine/Sarcosine N-methyltransferase GO:0017174 Reactome: R-HSA-2408508|Reactome: R-HSA-389661 THITH_16330 f9b3e095c956d3d0bec8e969e5cea43c 271 PIRSF PIRSF000385 204 264 0.32 T 13-10-2018 IPR014369 Glycine/Sarcosine N-methyltransferase GO:0017174 Reactome: R-HSA-2408508|Reactome: R-HSA-389661 THITH_16330 f9b3e095c956d3d0bec8e969e5cea43c 271 SUPERFAMILY SSF53335 19 262 6.23E-40 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_16330 f9b3e095c956d3d0bec8e969e5cea43c 271 Gene3D G3DSA:3.40.50.150 42 260 2.2E-62 T 13-10-2018 THITH_15485 e81cfbb7f415f856b2e8557dcae8835e 114 SMART SM00938 6 103 0.0012 T 13-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 THITH_15485 e81cfbb7f415f856b2e8557dcae8835e 114 SUPERFAMILY SSF54913 1 101 4.45E-15 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THITH_15485 e81cfbb7f415f856b2e8557dcae8835e 114 Gene3D G3DSA:3.30.70.120 1 99 4.1E-10 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THITH_13595 b1d47fa420bc395631dfaaf5c5c88dfb 198 Gene3D G3DSA:3.40.50.150 1 194 1.1E-19 T 13-10-2018 THITH_13595 b1d47fa420bc395631dfaaf5c5c88dfb 198 Pfam PF06080 Protein of unknown function (DUF938) 3 196 4.4E-63 T 13-10-2018 IPR010342 Protein of unknown function DUF938 THITH_13595 b1d47fa420bc395631dfaaf5c5c88dfb 198 SUPERFAMILY SSF53335 15 195 1.42E-25 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 30 174 3.8E-41 T 13-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 Gene3D G3DSA:3.40.50.1370 162 309 3.7E-90 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 29 332 40.368 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 76 83 - T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 183 328 2.3E-22 T 13-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 PRINTS PR00101 Aspartate carbamoyltransferase signature 104 113 8.1E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 PRINTS PR00101 Aspartate carbamoyltransferase signature 66 88 8.1E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 PRINTS PR00101 Aspartate carbamoyltransferase signature 161 178 8.1E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 PRINTS PR00101 Aspartate carbamoyltransferase signature 246 255 8.1E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 PRINTS PR00101 Aspartate carbamoyltransferase signature 311 325 8.1E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 PRINTS PR00101 Aspartate carbamoyltransferase signature 287 292 8.1E-31 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 SUPERFAMILY SSF53671 28 331 7.46E-93 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 162 173 2.0E-17 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 76 95 2.0E-17 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 283 292 2.0E-17 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 295 318 2.0E-17 T 13-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 30 330 2.2E-92 T 13-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_16020 3e81e6634c6f500b31a7f90815eef9fd 335 Gene3D G3DSA:3.40.50.1370 34 325 3.7E-90 T 13-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 THITH_16725 1b36af3ec2ef0df94c3eb45cc811a601 875 SMART SM00926 54 108 3.4E-5 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_16725 1b36af3ec2ef0df94c3eb45cc811a601 875 SUPERFAMILY SSF50692 733 874 5.65E-24 T 13-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily THITH_16725 1b36af3ec2ef0df94c3eb45cc811a601 875 Gene3D G3DSA:2.20.25.90 51 112 5.0E-12 T 13-10-2018 THITH_16725 1b36af3ec2ef0df94c3eb45cc811a601 875 SUPERFAMILY SSF53706 55 740 3.53E-119 T 13-10-2018 THITH_16725 1b36af3ec2ef0df94c3eb45cc811a601 875 Pfam PF00384 Molybdopterin oxidoreductase 111 549 7.0E-35 T 13-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_16725 1b36af3ec2ef0df94c3eb45cc811a601 875 Gene3D G3DSA:2.40.40.20 718 875 2.2E-25 T 13-10-2018 THITH_16725 1b36af3ec2ef0df94c3eb45cc811a601 875 Gene3D G3DSA:3.40.228.10 200 304 1.3E-45 T 13-10-2018 THITH_16725 1b36af3ec2ef0df94c3eb45cc811a601 875 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 56 101 2.3E-6 T 13-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_16725 1b36af3ec2ef0df94c3eb45cc811a601 875 Gene3D G3DSA:3.40.50.740 113 199 1.3E-45 T 13-10-2018 THITH_16725 1b36af3ec2ef0df94c3eb45cc811a601 875 Pfam PF01568 Molydopterin dinucleotide binding domain 764 862 1.7E-12 T 13-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 THITH_12770 fa3d1d10af7db8131567e76f6a289fb7 415 Pfam PF00266 Aminotransferase class-V 36 403 3.1E-146 T 13-10-2018 IPR000192 Aminotransferase class V domain THITH_12770 fa3d1d10af7db8131567e76f6a289fb7 415 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 17 414 3.1E-174 T 13-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 THITH_12770 fa3d1d10af7db8131567e76f6a289fb7 415 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 226 245 - T 13-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site THITH_12770 fa3d1d10af7db8131567e76f6a289fb7 415 Gene3D G3DSA:3.40.640.10 46 305 1.2E-172 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_12770 fa3d1d10af7db8131567e76f6a289fb7 415 SUPERFAMILY SSF53383 14 409 3.5E-123 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_12770 fa3d1d10af7db8131567e76f6a289fb7 415 Gene3D G3DSA:3.90.1150.10 18 407 1.2E-172 T 13-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 THITH_10320 3032d4ace8e2c2087926bb34d096472e 460 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 8 456 4.6E-102 T 13-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 THITH_10320 3032d4ace8e2c2087926bb34d096472e 460 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 5 457 15.696 T 13-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 THITH_10320 3032d4ace8e2c2087926bb34d096472e 460 Pfam PF00361 Proton-conducting membrane transporter 118 405 8.9E-62 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_15195 e3b8b1da3362058b662716f226b2c7e5 343 SUPERFAMILY SSF53850 29 339 2.47E-81 T 13-10-2018 THITH_15195 e3b8b1da3362058b662716f226b2c7e5 343 Gene3D G3DSA:3.40.190.10 31 306 5.9E-131 T 13-10-2018 THITH_15195 e3b8b1da3362058b662716f226b2c7e5 343 Gene3D G3DSA:3.40.190.10 129 340 5.9E-131 T 13-10-2018 THITH_15195 e3b8b1da3362058b662716f226b2c7e5 343 PIRSF PIRSF002825 1 343 9.6E-92 T 13-10-2018 IPR026045 Ferric binding protein THITH_15195 e3b8b1da3362058b662716f226b2c7e5 343 Pfam PF13343 Bacterial extracellular solute-binding protein 76 304 5.1E-22 T 13-10-2018 THITH_04180 cc817155b695b1333ed2360786c9af2f 188 Gene3D G3DSA:1.20.58.320 4 86 3.7E-26 T 13-10-2018 THITH_04180 cc817155b695b1333ed2360786c9af2f 188 Pfam PF06041 Bacterial protein of unknown function (DUF924) 14 182 6.1E-57 T 13-10-2018 IPR010323 Protein of unknown function DUF924 THITH_04180 cc817155b695b1333ed2360786c9af2f 188 Gene3D G3DSA:1.25.40.10 87 187 3.9E-33 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_04180 cc817155b695b1333ed2360786c9af2f 188 SUPERFAMILY SSF48452 9 181 7.21E-60 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_06865 b711c65c543f39b1d0a4923e9e2d912a 202 PIRSF PIRSF000013 7 200 8.5E-58 T 13-10-2018 IPR024717 Denitrification system component NapC/NirT/NrfH GO:0016021|GO:0019333|GO:0020037 THITH_06865 b711c65c543f39b1d0a4923e9e2d912a 202 Gene3D G3DSA:1.10.3820.10 22 201 7.8E-32 T 13-10-2018 IPR038266 NapC/NirT cytochrome c superfamily THITH_06865 b711c65c543f39b1d0a4923e9e2d912a 202 SUPERFAMILY SSF48695 17 188 1.31E-33 T 13-10-2018 IPR036280 Multiheme cytochrome superfamily THITH_06865 b711c65c543f39b1d0a4923e9e2d912a 202 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 25 191 6.0E-56 T 13-10-2018 IPR005126 NapC/NirT cytochrome c, N-terminal THITH_10895 ef9b055ecc3e88358a8e5495d617ba69 298 Gene3D G3DSA:1.10.3720.10 51 296 1.9E-70 T 13-10-2018 IPR035906 MetI-like superfamily THITH_10895 ef9b055ecc3e88358a8e5495d617ba69 298 SUPERFAMILY SSF161098 55 286 1.83E-58 T 13-10-2018 IPR035906 MetI-like superfamily THITH_10895 ef9b055ecc3e88358a8e5495d617ba69 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 289 5.8E-18 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THITH_01255 f46fb66790fbadc2c1f936e9908aeb88 304 Gene3D G3DSA:3.30.930.10 1 214 1.1E-110 T 13-10-2018 THITH_01255 f46fb66790fbadc2c1f936e9908aeb88 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 251 267 1.5E-69 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THITH_01255 f46fb66790fbadc2c1f936e9908aeb88 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 161 176 1.5E-69 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THITH_01255 f46fb66790fbadc2c1f936e9908aeb88 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 112 136 1.5E-69 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THITH_01255 f46fb66790fbadc2c1f936e9908aeb88 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 81 101 1.5E-69 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THITH_01255 f46fb66790fbadc2c1f936e9908aeb88 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 60 75 1.5E-69 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THITH_01255 f46fb66790fbadc2c1f936e9908aeb88 304 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 138 158 1.5E-69 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THITH_01255 f46fb66790fbadc2c1f936e9908aeb88 304 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 8 290 6.9E-150 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THITH_01255 f46fb66790fbadc2c1f936e9908aeb88 304 SUPERFAMILY SSF55681 7 290 9.57E-134 T 13-10-2018 THITH_01255 f46fb66790fbadc2c1f936e9908aeb88 304 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 7 297 7.4E-161 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THITH_01255 f46fb66790fbadc2c1f936e9908aeb88 304 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 6 291 60.885 T 13-10-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 THITH_01255 f46fb66790fbadc2c1f936e9908aeb88 304 Gene3D G3DSA:1.20.58.180 215 295 1.1E-33 T 13-10-2018 THITH_09420 d414da4bebb8dd961b4c064ccb2bf74e 314 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 254 311 1.0E-9 T 13-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 THITH_09420 d414da4bebb8dd961b4c064ccb2bf74e 314 SUPERFAMILY SSF117916 244 312 2.4E-16 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily THITH_09420 d414da4bebb8dd961b4c064ccb2bf74e 314 Gene3D G3DSA:3.30.300.130 240 314 2.5E-20 T 13-10-2018 IPR034904 Fe-S cluster assembly domain superfamily THITH_09420 d414da4bebb8dd961b4c064ccb2bf74e 314 Pfam PF01106 NifU-like domain 246 311 1.6E-19 T 13-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 THITH_08170 78d6ce83b76ed3ce5e3d13a3f3378960 209 SUPERFAMILY SSF52172 1 168 1.57E-36 T 13-10-2018 IPR011006 CheY-like superfamily THITH_08170 78d6ce83b76ed3ce5e3d13a3f3378960 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 1.5E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_08170 78d6ce83b76ed3ce5e3d13a3f3378960 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 1.5E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_08170 78d6ce83b76ed3ce5e3d13a3f3378960 209 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 1.5E-14 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_08170 78d6ce83b76ed3ce5e3d13a3f3378960 209 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_08170 78d6ce83b76ed3ce5e3d13a3f3378960 209 Pfam PF00196 Bacterial regulatory proteins, luxR family 148 201 6.1E-22 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_08170 78d6ce83b76ed3ce5e3d13a3f3378960 209 Gene3D G3DSA:3.40.50.12740 1 206 3.4E-70 T 13-10-2018 THITH_08170 78d6ce83b76ed3ce5e3d13a3f3378960 209 SMART SM00448 1 112 6.4E-30 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_08170 78d6ce83b76ed3ce5e3d13a3f3378960 209 SMART SM00421 145 202 1.1E-25 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_08170 78d6ce83b76ed3ce5e3d13a3f3378960 209 Pfam PF00072 Response regulator receiver domain 1 112 1.4E-31 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_02935 e7001e93d0661c95ae43d0a646b49cec 262 Hamap MF_02066 Cell division coordinator CpoB [cpoB]. 17 259 18.986 T 13-10-2018 IPR034706 Cell division coordinator CpoB GO:0051301 THITH_02935 e7001e93d0661c95ae43d0a646b49cec 262 SMART SM00028 176 209 8.1 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_02935 e7001e93d0661c95ae43d0a646b49cec 262 SMART SM00028 213 246 25.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_02935 e7001e93d0661c95ae43d0a646b49cec 262 SUPERFAMILY SSF48452 143 245 1.27E-14 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_02935 e7001e93d0661c95ae43d0a646b49cec 262 Pfam PF13525 Outer membrane lipoprotein 135 196 6.6E-8 T 13-10-2018 IPR039565 Outer membrane lipoprotein BamD-like THITH_02935 e7001e93d0661c95ae43d0a646b49cec 262 Pfam PF13174 Tetratricopeptide repeat 214 244 3.5E-7 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_02935 e7001e93d0661c95ae43d0a646b49cec 262 TIGRFAM TIGR02795 tol_pal_ybgF: tol-pal system protein YbgF 139 256 1.3E-31 T 13-10-2018 IPR014162 Cell division coordinator CpoB, C-terminal THITH_02935 e7001e93d0661c95ae43d0a646b49cec 262 Gene3D G3DSA:1.25.40.10 140 260 4.4E-30 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_02935 e7001e93d0661c95ae43d0a646b49cec 262 Pfam PF16331 TolA binding protein trimerisation 49 117 6.4E-15 T 13-10-2018 IPR032519 YbgF, trimerisation domain GO:0070206 THITH_16160 e32ba23952d42fd285b491c821abfb38 179 TIGRFAM TIGR00385 dsbE: periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily 29 172 1.4E-45 T 13-10-2018 IPR004799 Periplasmic protein thiol:disulphide oxidoreductase DsbE GO:0015036|GO:0017004|GO:0030288 THITH_16160 e32ba23952d42fd285b491c821abfb38 179 ProSitePatterns PS00194 Thioredoxin family active site. 68 86 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 THITH_16160 e32ba23952d42fd285b491c821abfb38 179 SUPERFAMILY SSF52833 43 174 2.4E-32 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_16160 e32ba23952d42fd285b491c821abfb38 179 Pfam PF08534 Redoxin 38 162 4.0E-16 T 13-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 THITH_16160 e32ba23952d42fd285b491c821abfb38 179 Gene3D G3DSA:3.40.30.10 28 179 2.3E-37 T 13-10-2018 THITH_09120 707365a2db7ef194a850570b91bec00d 218 Gene3D G3DSA:3.40.50.2300 2 131 3.6E-42 T 13-10-2018 THITH_09120 707365a2db7ef194a850570b91bec00d 218 SMART SM00421 140 197 5.1E-20 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_09120 707365a2db7ef194a850570b91bec00d 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 157 184 - T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_09120 707365a2db7ef194a850570b91bec00d 218 SUPERFAMILY SSF46894 129 197 4.42E-19 T 13-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 THITH_09120 707365a2db7ef194a850570b91bec00d 218 SMART SM00448 5 116 1.2E-32 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_09120 707365a2db7ef194a850570b91bec00d 218 SUPERFAMILY SSF52172 6 142 3.7E-34 T 13-10-2018 IPR011006 CheY-like superfamily THITH_09120 707365a2db7ef194a850570b91bec00d 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 185 1.9E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_09120 707365a2db7ef194a850570b91bec00d 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 157 173 1.9E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_09120 707365a2db7ef194a850570b91bec00d 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 143 157 1.9E-12 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_09120 707365a2db7ef194a850570b91bec00d 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 197 2.2E-19 T 13-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 THITH_09120 707365a2db7ef194a850570b91bec00d 218 Gene3D G3DSA:1.10.10.10 134 199 1.1E-20 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_09120 707365a2db7ef194a850570b91bec00d 218 Pfam PF00072 Response regulator receiver domain 7 117 3.6E-28 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_13695 491e01924f398e1438d6b96fd68fc29e 94 Gene3D G3DSA:3.30.70.2330 1 91 9.2E-15 T 13-10-2018 THITH_13695 491e01924f398e1438d6b96fd68fc29e 94 SMART SM00910 1 92 7.2E-7 T 13-10-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 THITH_13695 491e01924f398e1438d6b96fd68fc29e 94 Pfam PF08797 HIRAN domain 9 91 2.9E-9 T 13-10-2018 IPR014905 HIRAN domain GO:0003676|GO:0008270|GO:0016818 Reactome: R-HSA-8866654 THITH_13395 35bf9f087955b4544652de7cbd22be5a 182 SUPERFAMILY SSF101478 12 158 7.85E-24 T 13-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily THITH_13395 35bf9f087955b4544652de7cbd22be5a 182 Gene3D G3DSA:1.10.4080.10 6 169 2.2E-28 T 13-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily THITH_13395 35bf9f087955b4544652de7cbd22be5a 182 Pfam PF03747 ADP-ribosylglycohydrolase 11 134 5.8E-22 T 13-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 THITH_13810 1aecbb3f4e1e2b80129009bf7a54f4a1 480 SUPERFAMILY SSF56935 324 469 3.43E-6 T 13-10-2018 THITH_03855 7277f2be8ce847162b2f76143ba0bfed 296 Pfam PF01435 Peptidase family M48 81 294 1.8E-40 T 13-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 THITH_03855 7277f2be8ce847162b2f76143ba0bfed 296 Hamap MF_00188 Protease HtpX [htpX]. 1 294 24.992 T 13-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 THITH_03855 7277f2be8ce847162b2f76143ba0bfed 296 Gene3D G3DSA:3.30.2010.10 72 165 6.8E-34 T 13-10-2018 THITH_12880 18cd965b1614ea4763c5f214a55fe90e 206 SUPERFAMILY SSF53335 6 190 1.7E-37 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_12880 18cd965b1614ea4763c5f214a55fe90e 206 Pfam PF08241 Methyltransferase domain 45 140 1.6E-21 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 THITH_12880 18cd965b1614ea4763c5f214a55fe90e 206 Gene3D G3DSA:3.40.50.150 4 190 2.7E-35 T 13-10-2018 THITH_09195 096c627e517ff1689894028246cc068d 317 SUPERFAMILY SSF46565 1 110 1.31E-32 T 13-10-2018 IPR036869 Chaperone J-domain superfamily THITH_09195 096c627e517ff1689894028246cc068d 317 PRINTS PR00625 DnaJ domain signature 25 40 7.4E-24 T 13-10-2018 IPR001623 DnaJ domain THITH_09195 096c627e517ff1689894028246cc068d 317 PRINTS PR00625 DnaJ domain signature 7 25 7.4E-24 T 13-10-2018 IPR001623 DnaJ domain THITH_09195 096c627e517ff1689894028246cc068d 317 PRINTS PR00625 DnaJ domain signature 41 61 7.4E-24 T 13-10-2018 IPR001623 DnaJ domain THITH_09195 096c627e517ff1689894028246cc068d 317 PRINTS PR00625 DnaJ domain signature 61 80 7.4E-24 T 13-10-2018 IPR001623 DnaJ domain THITH_09195 096c627e517ff1689894028246cc068d 317 Pfam PF01556 DnaJ C terminal domain 137 289 3.7E-28 T 13-10-2018 IPR002939 Chaperone DnaJ, C-terminal THITH_09195 096c627e517ff1689894028246cc068d 317 Gene3D G3DSA:2.60.260.20 212 289 6.8E-22 T 13-10-2018 THITH_09195 096c627e517ff1689894028246cc068d 317 SUPERFAMILY SSF49493 128 225 2.09E-17 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THITH_09195 096c627e517ff1689894028246cc068d 317 SUPERFAMILY SSF49493 219 294 3.53E-15 T 13-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 THITH_09195 096c627e517ff1689894028246cc068d 317 Pfam PF00226 DnaJ domain 5 66 4.3E-25 T 13-10-2018 IPR001623 DnaJ domain THITH_09195 096c627e517ff1689894028246cc068d 317 Gene3D G3DSA:1.10.287.110 2 124 2.3E-36 T 13-10-2018 IPR036869 Chaperone J-domain superfamily THITH_09195 096c627e517ff1689894028246cc068d 317 Gene3D G3DSA:2.60.260.20 130 211 3.1E-20 T 13-10-2018 THITH_09195 096c627e517ff1689894028246cc068d 317 SMART SM00271 4 61 2.9E-29 T 13-10-2018 IPR001623 DnaJ domain THITH_00275 e471cb9600ff425af06cbc5f791eeeaf 73 Pfam PF07927 HicA toxin of bacterial toxin-antitoxin, 10 62 2.3E-17 T 13-10-2018 IPR012933 HicA mRNA interferase family GO:0003729 THITH_00275 e471cb9600ff425af06cbc5f791eeeaf 73 Gene3D G3DSA:3.30.920.30 6 69 7.9E-16 T 13-10-2018 IPR038570 HicA superfamily THITH_00275 e471cb9600ff425af06cbc5f791eeeaf 73 SUPERFAMILY SSF54786 4 69 3.41E-16 T 13-10-2018 THITH_04900 172f407b3a130ce4d4a255dba67f9c00 156 Gene3D G3DSA:3.40.1260.10 2 156 1.7E-40 T 13-10-2018 IPR027396 DsrEFH-like THITH_04900 172f407b3a130ce4d4a255dba67f9c00 156 Pfam PF13686 DsrE/DsrF/DrsH-like family 4 155 1.3E-54 T 13-10-2018 IPR032836 DsrE2-like family THITH_04900 172f407b3a130ce4d4a255dba67f9c00 156 SUPERFAMILY SSF75169 5 155 3.09E-21 T 13-10-2018 IPR027396 DsrEFH-like THITH_03135 685eaf32d467e181fa634dc0914d0c24 721 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 341 654 2.5E-53 T 13-10-2018 IPR011749 Conserved hypothetical protein CHP02243 THITH_03135 685eaf32d467e181fa634dc0914d0c24 721 Pfam PF04865 Baseplate J-like protein 435 615 2.6E-11 T 13-10-2018 IPR006949 Baseplate protein J-like THITH_11820 cd0641f336415907bb1a595a17ab0e05 183 Gene3D G3DSA:3.10.50.40 29 176 9.3E-37 T 13-10-2018 THITH_11820 cd0641f336415907bb1a595a17ab0e05 183 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 75 161 5.7E-19 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain THITH_11820 cd0641f336415907bb1a595a17ab0e05 183 SUPERFAMILY SSF54534 34 163 8.05E-37 T 13-10-2018 THITH_04450 d1fd3849d4e4ec4f990b720d5a91cb7a 157 Pfam PF01899 Na+/H+ ion antiporter subunit 7 154 8.6E-44 T 13-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 THITH_04450 d1fd3849d4e4ec4f990b720d5a91cb7a 157 PIRSF PIRSF019239 1 157 3.8E-46 T 13-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 THITH_13790 7f51c94b9e94a5342978698802917df1 325 Gene3D G3DSA:3.100.10.20 11 113 1.0E-48 T 13-10-2018 THITH_13790 7f51c94b9e94a5342978698802917df1 325 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 19 313 1.1E-62 T 13-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THITH_13790 7f51c94b9e94a5342978698802917df1 325 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 16 320 15.644 T 13-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THITH_13790 7f51c94b9e94a5342978698802917df1 325 Pfam PF01867 CRISPR associated protein Cas1 27 272 1.3E-10 T 13-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 THITH_13790 7f51c94b9e94a5342978698802917df1 325 TIGRFAM TIGR03637 cas1_YPEST: CRISPR-associated endonuclease Cas1, subtype I-F/YPEST 12 317 1.1E-152 T 13-10-2018 IPR019857 CRISPR-associated protein Cas1, YPEST subtype GO:0004520|GO:0043571|GO:0046872 THITH_13790 7f51c94b9e94a5342978698802917df1 325 Gene3D G3DSA:1.20.120.920 114 324 1.0E-61 T 13-10-2018 THITH_03765 8e84fe6854eb4ef6e5d6e7f28a08b9ff 118 Pfam PF01844 HNH endonuclease 39 87 1.3E-11 T 13-10-2018 IPR002711 HNH endonuclease GO:0003676|GO:0004519 THITH_03765 8e84fe6854eb4ef6e5d6e7f28a08b9ff 118 SMART SM00507 27 82 2.0E-4 T 13-10-2018 IPR003615 HNH nuclease THITH_01195 f1637fcae4c801e9a43c39723ac0ba92 284 Gene3D G3DSA:3.40.50.620 5 146 2.5E-30 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_01195 f1637fcae4c801e9a43c39723ac0ba92 284 PRINTS PR01438 Universal stress protein signature 11 29 4.4E-20 T 13-10-2018 IPR006015 Universal stress protein A THITH_01195 f1637fcae4c801e9a43c39723ac0ba92 284 PRINTS PR01438 Universal stress protein signature 259 281 4.4E-20 T 13-10-2018 IPR006015 Universal stress protein A THITH_01195 f1637fcae4c801e9a43c39723ac0ba92 284 PRINTS PR01438 Universal stress protein signature 241 253 4.4E-20 T 13-10-2018 IPR006015 Universal stress protein A THITH_01195 f1637fcae4c801e9a43c39723ac0ba92 284 SUPERFAMILY SSF52402 11 149 1.42E-31 T 13-10-2018 THITH_01195 f1637fcae4c801e9a43c39723ac0ba92 284 SUPERFAMILY SSF52402 157 281 1.42E-32 T 13-10-2018 THITH_01195 f1637fcae4c801e9a43c39723ac0ba92 284 Gene3D G3DSA:3.40.50.620 149 281 9.6E-33 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_01195 f1637fcae4c801e9a43c39723ac0ba92 284 Pfam PF00582 Universal stress protein family 156 281 2.6E-26 T 13-10-2018 IPR006016 UspA THITH_01195 f1637fcae4c801e9a43c39723ac0ba92 284 Pfam PF00582 Universal stress protein family 11 147 1.4E-26 T 13-10-2018 IPR006016 UspA THITH_07895 ed004314f6831bad393ed90fabf7b780 344 SUPERFAMILY SSF55909 3 339 8.57E-120 T 13-10-2018 THITH_07895 ed004314f6831bad393ed90fabf7b780 344 Pfam PF04371 Porphyromonas-type peptidyl-arginine deiminase 4 338 2.6E-113 T 13-10-2018 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type GO:0004668|GO:0009446 KEGG: 00330+3.5.3.12|MetaCyc: PWY-43 THITH_07895 ed004314f6831bad393ed90fabf7b780 344 Gene3D G3DSA:3.75.10.10 1 343 2.3E-124 T 13-10-2018 THITH_10310 8be3c92ee108310b49fdb9e8d3d33ff4 267 SUPERFAMILY SSF56059 71 238 2.23E-11 T 13-10-2018 THITH_13260 2dd397aa69c0fd0a528960be0617dc9f 290 PRINTS PR01374 Gram-negative bacterial tonB protein signature 205 226 1.4E-9 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 THITH_13260 2dd397aa69c0fd0a528960be0617dc9f 290 PRINTS PR01374 Gram-negative bacterial tonB protein signature 148 158 1.4E-9 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 THITH_13260 2dd397aa69c0fd0a528960be0617dc9f 290 PRINTS PR01374 Gram-negative bacterial tonB protein signature 226 244 1.4E-9 T 13-10-2018 IPR003538 Gram-negative bacterial TonB protein GO:0015343|GO:0015891|GO:0030288|GO:0031992 THITH_13260 2dd397aa69c0fd0a528960be0617dc9f 290 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 211 287 5.2E-22 T 13-10-2018 IPR006260 TonB/TolA, C-terminal THITH_13260 2dd397aa69c0fd0a528960be0617dc9f 290 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 209 287 3.4E-25 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 THITH_13260 2dd397aa69c0fd0a528960be0617dc9f 290 SUPERFAMILY SSF74653 203 285 6.28E-25 T 13-10-2018 THITH_13260 2dd397aa69c0fd0a528960be0617dc9f 290 Gene3D G3DSA:3.30.1150.10 195 288 6.6E-28 T 13-10-2018 THITH_09870 972b525a53adef28f02ff9ffa883fd27 856 Gene3D G3DSA:3.40.50.2000 199 383 4.3E-49 T 13-10-2018 THITH_09870 972b525a53adef28f02ff9ffa883fd27 856 Gene3D G3DSA:3.40.50.2000 64 397 4.3E-49 T 13-10-2018 THITH_09870 972b525a53adef28f02ff9ffa883fd27 856 Gene3D G3DSA:3.40.50.2000 661 815 3.4E-27 T 13-10-2018 THITH_09870 972b525a53adef28f02ff9ffa883fd27 856 SUPERFAMILY SSF53756 16 402 1.18E-60 T 13-10-2018 THITH_09870 972b525a53adef28f02ff9ffa883fd27 856 Pfam PF00534 Glycosyl transferases group 1 665 807 2.1E-25 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 THITH_09870 972b525a53adef28f02ff9ffa883fd27 856 Pfam PF00534 Glycosyl transferases group 1 223 378 3.7E-27 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 THITH_09870 972b525a53adef28f02ff9ffa883fd27 856 SUPERFAMILY SSF53756 474 808 1.12E-45 T 13-10-2018 THITH_15255 5f9420ac820c6d29698da5923f483962 174 SUPERFAMILY SSF160387 59 170 4.71E-28 T 13-10-2018 THITH_15255 5f9420ac820c6d29698da5923f483962 174 Pfam PF05573 NosL 37 165 8.2E-33 T 13-10-2018 IPR008719 Nitrous oxide reductase accessory protein NosL THITH_15255 5f9420ac820c6d29698da5923f483962 174 Gene3D G3DSA:3.30.70.2050 118 172 4.7E-11 T 13-10-2018 THITH_00830 090f73bc352f39c6f1155511052cad79 190 Pfam PF13463 Winged helix DNA-binding domain 46 98 1.6E-9 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THITH_00830 090f73bc352f39c6f1155511052cad79 190 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 13-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site THITH_00830 090f73bc352f39c6f1155511052cad79 190 SUPERFAMILY SSF46785 5 137 4.5E-23 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_00830 090f73bc352f39c6f1155511052cad79 190 Gene3D G3DSA:1.10.10.10 2 135 1.3E-24 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_00830 090f73bc352f39c6f1155511052cad79 190 SMART SM00347 19 123 6.2E-4 T 13-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 THITH_13750 b082313ec98585463bdc73fc697010e1 91 Gene3D G3DSA:3.40.50.300 10 50 1.2E-31 T 13-10-2018 THITH_13750 b082313ec98585463bdc73fc697010e1 91 SUPERFAMILY SSF52540 8 82 1.77E-25 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13750 b082313ec98585463bdc73fc697010e1 91 Gene3D G3DSA:1.20.120.850 51 79 1.2E-31 T 13-10-2018 THITH_09570 d9c61de5efa83dab11c31fbac9d2d1b4 99 Pfam PF03795 YCII-related domain 1 95 8.4E-30 T 13-10-2018 IPR005545 YCII-related THITH_09570 d9c61de5efa83dab11c31fbac9d2d1b4 99 Gene3D G3DSA:3.30.70.1060 1 98 3.0E-35 T 13-10-2018 THITH_09570 d9c61de5efa83dab11c31fbac9d2d1b4 99 SUPERFAMILY SSF54909 1 97 3.86E-32 T 13-10-2018 IPR011008 Dimeric alpha-beta barrel THITH_00990 04f703522817ce4c393f9003e40b02e9 254 SMART SM00471 79 214 4.0E-8 T 13-10-2018 IPR003607 HD/PDEase domain THITH_00990 04f703522817ce4c393f9003e40b02e9 254 Pfam PF13487 HD domain 134 196 2.3E-19 T 13-10-2018 THITH_00990 04f703522817ce4c393f9003e40b02e9 254 SUPERFAMILY SSF109604 71 245 8.11E-35 T 13-10-2018 THITH_00990 04f703522817ce4c393f9003e40b02e9 254 Gene3D G3DSA:1.10.3210.10 58 248 1.2E-66 T 13-10-2018 THITH_00990 04f703522817ce4c393f9003e40b02e9 254 TIGRFAM TIGR00277 HDIG: HDIG domain 83 173 3.3E-8 T 13-10-2018 IPR006675 HDIG domain THITH_15775 75ff234401b9b202243233a1c4fd4ff6 182 Pfam PF04542 Sigma-70 region 2 17 79 3.6E-14 T 13-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 THITH_15775 75ff234401b9b202243233a1c4fd4ff6 182 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 10 163 6.2E-27 T 13-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 THITH_15775 75ff234401b9b202243233a1c4fd4ff6 182 SUPERFAMILY SSF88659 103 164 4.11E-16 T 13-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like THITH_15775 75ff234401b9b202243233a1c4fd4ff6 182 Gene3D G3DSA:1.10.10.10 107 166 6.2E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_15775 75ff234401b9b202243233a1c4fd4ff6 182 Gene3D G3DSA:1.10.1740.10 2 81 1.9E-19 T 13-10-2018 THITH_15775 75ff234401b9b202243233a1c4fd4ff6 182 SUPERFAMILY SSF88946 9 93 4.71E-18 T 13-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 THITH_15775 75ff234401b9b202243233a1c4fd4ff6 182 Pfam PF08281 Sigma-70, region 4 109 159 6.0E-14 T 13-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 THITH_01240 99d21a9089b59030e2847e224dff8b68 246 Gene3D G3DSA:3.40.50.720 5 245 2.9E-74 T 13-10-2018 THITH_01240 99d21a9089b59030e2847e224dff8b68 246 Pfam PF00899 ThiF family 11 176 2.0E-37 T 13-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 THITH_01240 99d21a9089b59030e2847e224dff8b68 246 SUPERFAMILY SSF69572 11 245 2.88E-54 T 13-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 THITH_09740 3923a6f9682d99c5ac9dd87c6203010f 186 SUPERFAMILY SSF52980 3 184 7.51E-35 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_09740 3923a6f9682d99c5ac9dd87c6203010f 186 Pfam PF05685 Putative restriction endonuclease 11 173 1.1E-23 T 13-10-2018 IPR008538 Domain of unknown function DUF820 THITH_09740 3923a6f9682d99c5ac9dd87c6203010f 186 Gene3D G3DSA:3.90.1570.10 3 181 6.5E-36 T 13-10-2018 THITH_07035 b9fc7b2dfec2ed39b674e99f13b7d02f 131 PIRSF PIRSF029543 1 131 8.0E-33 T 13-10-2018 IPR016924 Uncharacterised conserved protein UCP029543 THITH_09070 3c18e67fbb7308bce9faf9f6fa06ae07 87 Gene3D G3DSA:3.30.460.10 2 85 2.4E-18 T 13-10-2018 THITH_09070 3c18e67fbb7308bce9faf9f6fa06ae07 87 SUPERFAMILY SSF81301 3 87 8.56E-20 T 13-10-2018 THITH_09070 3c18e67fbb7308bce9faf9f6fa06ae07 87 Pfam PF01909 Nucleotidyltransferase domain 1 86 6.1E-11 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THITH_10870 2929a8c6e8a6daec5bd59ed227db5f62 877 SUPERFAMILY SSF56059 292 684 4.0E-33 T 13-10-2018 THITH_10870 2929a8c6e8a6daec5bd59ed227db5f62 877 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 298 672 2.0E-43 T 13-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 THITH_10870 2929a8c6e8a6daec5bd59ed227db5f62 877 Gene3D G3DSA:3.30.1490.20 329 473 2.8E-16 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 THITH_07165 0c2e0e3a7de2da92f0e1fdb22ff0c1a1 499 Pfam PF07556 Protein of unknown function (DUF1538) 21 231 1.5E-58 T 13-10-2018 IPR011435 Protein of unknown function DUF1538 THITH_07165 0c2e0e3a7de2da92f0e1fdb22ff0c1a1 499 Pfam PF07556 Protein of unknown function (DUF1538) 280 489 7.2E-55 T 13-10-2018 IPR011435 Protein of unknown function DUF1538 THITH_04040 0866e44c418aee6c760fc169abad2fa8 153 SMART SM00671 75 110 3.0E-10 T 13-10-2018 IPR006597 Sel1-like repeat THITH_04040 0866e44c418aee6c760fc169abad2fa8 153 SMART SM00671 39 74 9.0E-6 T 13-10-2018 IPR006597 Sel1-like repeat THITH_04040 0866e44c418aee6c760fc169abad2fa8 153 SMART SM00671 111 146 0.0063 T 13-10-2018 IPR006597 Sel1-like repeat THITH_04040 0866e44c418aee6c760fc169abad2fa8 153 Pfam PF08238 Sel1 repeat 75 109 1.0E-10 T 13-10-2018 IPR006597 Sel1-like repeat THITH_04040 0866e44c418aee6c760fc169abad2fa8 153 Pfam PF08238 Sel1 repeat 39 74 4.8E-4 T 13-10-2018 IPR006597 Sel1-like repeat THITH_04040 0866e44c418aee6c760fc169abad2fa8 153 Pfam PF08238 Sel1 repeat 117 141 1.2E-4 T 13-10-2018 IPR006597 Sel1-like repeat THITH_04040 0866e44c418aee6c760fc169abad2fa8 153 Gene3D G3DSA:1.25.40.10 5 151 7.3E-41 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_04040 0866e44c418aee6c760fc169abad2fa8 153 SUPERFAMILY SSF81901 11 141 1.96E-33 T 13-10-2018 THITH_05555 54a973344910f381b7cdeda541ac7d06 335 Gene3D G3DSA:3.30.1950.10 66 131 2.1E-10 T 13-10-2018 THITH_05555 54a973344910f381b7cdeda541ac7d06 335 Pfam PF02563 Polysaccharide biosynthesis/export protein 62 132 2.4E-20 T 13-10-2018 IPR003715 Polysaccharide export protein GO:0015159|GO:0015774|GO:0016020 THITH_05555 54a973344910f381b7cdeda541ac7d06 335 Gene3D G3DSA:3.10.560.10 132 225 6.0E-11 T 13-10-2018 THITH_05555 54a973344910f381b7cdeda541ac7d06 335 Gene3D G3DSA:3.10.560.10 227 310 6.6E-14 T 13-10-2018 THITH_05555 54a973344910f381b7cdeda541ac7d06 335 Pfam PF10531 SLBB domain 140 182 1.2E-10 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_05555 54a973344910f381b7cdeda541ac7d06 335 Pfam PF10531 SLBB domain 228 275 8.4E-9 T 13-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_16245 f5009abd156f34e3f0df8e2354848192 118 Pfam PF11743 Protein of unknown function (DUF3301) 5 96 1.0E-24 T 13-10-2018 IPR021732 Protein of unknown function DUF3301 THITH_02005 3c422553da0f8e6cf3487425d659ed53 200 Pfam PF14279 HNH endonuclease 96 150 1.7E-14 T 13-10-2018 IPR029471 HNH endonuclease 5 THITH_02005 3c422553da0f8e6cf3487425d659ed53 200 SMART SM00507 83 136 1.1E-7 T 13-10-2018 IPR003615 HNH nuclease THITH_02005 3c422553da0f8e6cf3487425d659ed53 200 Gene3D G3DSA:3.30.40.60 79 167 1.2E-20 T 13-10-2018 THITH_15350 d4497855a95ecae71c402842c9b7578e 198 SUPERFAMILY SSF53254 2 195 3.85E-45 T 13-10-2018 IPR029033 Histidine phosphatase superfamily THITH_15350 d4497855a95ecae71c402842c9b7578e 198 Gene3D G3DSA:3.40.50.1240 1 192 1.1E-42 T 13-10-2018 IPR029033 Histidine phosphatase superfamily THITH_15350 d4497855a95ecae71c402842c9b7578e 198 SMART SM00855 2 156 1.7E-11 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THITH_15350 d4497855a95ecae71c402842c9b7578e 198 PIRSF PIRSF000709 2 187 1.8E-11 T 13-10-2018 THITH_15350 d4497855a95ecae71c402842c9b7578e 198 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 5 190 1.4E-41 T 13-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 THITH_06160 33c6f06e7d2bfe3abcf8eaa8ca73e161 217 Gene3D G3DSA:2.40.70.10 97 216 3.9E-28 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily THITH_06160 33c6f06e7d2bfe3abcf8eaa8ca73e161 217 Pfam PF13975 gag-polyprotein putative aspartyl protease 111 202 2.5E-25 T 13-10-2018 THITH_06160 33c6f06e7d2bfe3abcf8eaa8ca73e161 217 TIGRFAM TIGR02281 clan_AA_DTGA: clan AA aspartic protease, TIGR02281 family 104 215 4.7E-28 T 13-10-2018 IPR011969 Clan AA aspartic peptidase, C-terminal THITH_06160 33c6f06e7d2bfe3abcf8eaa8ca73e161 217 SUPERFAMILY SSF50630 109 205 7.88E-16 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily THITH_06160 33c6f06e7d2bfe3abcf8eaa8ca73e161 217 ProSitePatterns PS00141 Eukaryotic and viral aspartyl proteases active site. 122 133 - T 13-10-2018 IPR001969 Aspartic peptidase, active site GO:0004190|GO:0006508 THITH_05845 d9d7acf2e91b0966b35619cb74488d68 95 Gene3D G3DSA:3.30.2310.40 1 93 3.3E-6 T 13-10-2018 IPR038493 Toxin MqsR superfamily THITH_05845 d9d7acf2e91b0966b35619cb74488d68 95 Pfam PF15723 Motility quorum-sensing regulator, toxin of MqsA 1 93 3.2E-21 T 13-10-2018 IPR031451 mRNA interferase toxin MqsR GO:0009372|GO:0017148|GO:0044010 THITH_08225 b8c61a4322c63548ec94adf562036fc7 214 Gene3D G3DSA:3.40.50.150 2 155 2.0E-27 T 13-10-2018 THITH_08225 b8c61a4322c63548ec94adf562036fc7 214 SUPERFAMILY SSF53335 1 175 8.97E-26 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_08225 b8c61a4322c63548ec94adf562036fc7 214 Pfam PF13649 Methyltransferase domain 44 140 2.0E-12 T 13-10-2018 THITH_16810 38daf93efeff9c8307e1f424756ab809 222 SUPERFAMILY SSF52540 7 202 2.15E-47 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16810 38daf93efeff9c8307e1f424756ab809 222 Gene3D G3DSA:3.40.50.300 2 220 1.1E-53 T 13-10-2018 THITH_16810 38daf93efeff9c8307e1f424756ab809 222 SMART SM00382 11 207 9.6E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_16810 38daf93efeff9c8307e1f424756ab809 222 Pfam PF00005 ABC transporter 6 159 2.0E-27 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_02065 54104829e6c32374ea90c41b23523c81 274 Pfam PF12849 PBP superfamily domain 34 251 6.4E-18 T 13-10-2018 IPR024370 PBP domain THITH_02065 54104829e6c32374ea90c41b23523c81 274 Gene3D G3DSA:3.40.190.10 109 221 4.2E-87 T 13-10-2018 THITH_02065 54104829e6c32374ea90c41b23523c81 274 Gene3D G3DSA:3.40.190.10 34 258 4.2E-87 T 13-10-2018 THITH_02065 54104829e6c32374ea90c41b23523c81 274 SUPERFAMILY SSF53850 38 260 3.32E-25 T 13-10-2018 THITH_11195 6fab10c9ca340c615a70ff14482c6f7b 189 Pfam PF13007 Transposase C of IS166 homeodomain 61 136 4.6E-14 T 13-10-2018 IPR024463 Transposase TnpC, homeodomain THITH_03835 c75a9e9936ed7e94094c50eb43c5561d 104 SUPERFAMILY SSF46626 1 88 9.73E-19 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_03835 c75a9e9936ed7e94094c50eb43c5561d 104 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 1 81 2.2E-12 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_03835 c75a9e9936ed7e94094c50eb43c5561d 104 Gene3D G3DSA:1.10.760.10 1 89 1.9E-16 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_06315 6aaff864ea897ad05c5f03109db43161 344 SUPERFAMILY SSF53955 53 343 3.66E-88 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily THITH_06315 6aaff864ea897ad05c5f03109db43161 344 Gene3D G3DSA:1.10.8.350 62 224 3.5E-107 T 13-10-2018 THITH_06315 6aaff864ea897ad05c5f03109db43161 344 Gene3D G3DSA:1.10.530.10 91 339 3.5E-107 T 13-10-2018 THITH_06315 6aaff864ea897ad05c5f03109db43161 344 Pfam PF13406 Transglycosylase SLT domain 52 340 2.2E-94 T 13-10-2018 IPR031304 Transglycosylase SLT domain 2 THITH_06315 6aaff864ea897ad05c5f03109db43161 344 TIGRFAM TIGR02282 MltB: lytic murein transglycosylase B 55 342 1.9E-104 T 13-10-2018 IPR011757 Lytic transglycosylase MltB THITH_01170 0830f0a90e3fa819fc84ffc129fd8aaf 146 Pfam PF01475 Ferric uptake regulator family 24 117 7.7E-20 T 13-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 THITH_01170 0830f0a90e3fa819fc84ffc129fd8aaf 146 Gene3D G3DSA:1.10.10.10 10 93 3.5E-22 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_01170 0830f0a90e3fa819fc84ffc129fd8aaf 146 SUPERFAMILY SSF46785 14 139 8.36E-26 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_15415 75b4512f8aaf2c28ce2357438f872876 119 SUPERFAMILY SSF69721 23 111 2.62E-24 T 13-10-2018 IPR025526 DsrC-like domain superfamily THITH_15415 75b4512f8aaf2c28ce2357438f872876 119 Gene3D G3DSA:1.10.10.370 53 112 4.9E-13 T 13-10-2018 THITH_15415 75b4512f8aaf2c28ce2357438f872876 119 PIRSF PIRSF006223 17 114 1.2E-15 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_15415 75b4512f8aaf2c28ce2357438f872876 119 Gene3D G3DSA:3.30.1420.10 21 51 2.4E-7 T 13-10-2018 THITH_15415 75b4512f8aaf2c28ce2357438f872876 119 Pfam PF04358 DsrC like protein 24 110 4.9E-19 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_10890 5b8c3f659ebdbb89ea5a984fc3503424 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 270 7.3E-19 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THITH_10890 5b8c3f659ebdbb89ea5a984fc3503424 277 Gene3D G3DSA:1.10.3720.10 2 268 1.8E-55 T 13-10-2018 IPR035906 MetI-like superfamily THITH_10890 5b8c3f659ebdbb89ea5a984fc3503424 277 SUPERFAMILY SSF161098 4 277 1.12E-62 T 13-10-2018 IPR035906 MetI-like superfamily THITH_00965 b8ed53cebf861b8981138fa6192d9720 153 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 4 70 2.8E-12 T 13-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain THITH_00965 b8ed53cebf861b8981138fa6192d9720 153 Gene3D G3DSA:3.10.50.40 2 152 5.1E-37 T 13-10-2018 THITH_00965 b8ed53cebf861b8981138fa6192d9720 153 SUPERFAMILY SSF54534 4 140 1.65E-30 T 13-10-2018 THITH_09665 0a86c2cee4e738430258463470900390 237 Pfam PF05875 Ceramidase 22 160 2.4E-9 T 13-10-2018 IPR008901 Ceramidase GO:0006672|GO:0016021|GO:0016811 Reactome: R-HSA-1660661 THITH_12690 d50330a264fad17aa0030e700af63b00 296 Pfam PF12833 Helix-turn-helix domain 213 291 1.3E-20 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THITH_12690 d50330a264fad17aa0030e700af63b00 296 Gene3D G3DSA:1.10.10.60 194 238 3.9E-12 T 13-10-2018 THITH_12690 d50330a264fad17aa0030e700af63b00 296 SUPERFAMILY SSF46689 243 291 5.82E-10 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_12690 d50330a264fad17aa0030e700af63b00 296 Gene3D G3DSA:1.10.10.60 239 295 1.8E-14 T 13-10-2018 THITH_12690 d50330a264fad17aa0030e700af63b00 296 SMART SM00342 207 289 2.0E-26 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THITH_12690 d50330a264fad17aa0030e700af63b00 296 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 244 285 - T 13-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 THITH_12690 d50330a264fad17aa0030e700af63b00 296 SUPERFAMILY SSF46689 193 241 7.62E-11 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_05130 32eb5c81e5b980aa124550eb00565ca4 413 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 5 399 30.712 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 THITH_05130 32eb5c81e5b980aa124550eb00565ca4 413 Pfam PF04551 GcpE protein 10 397 4.6E-114 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 THITH_05130 32eb5c81e5b980aa124550eb00565ca4 413 SUPERFAMILY SSF56014 292 405 2.22E-6 T 13-10-2018 THITH_05130 32eb5c81e5b980aa124550eb00565ca4 413 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 7 394 7.1E-120 T 13-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 THITH_05130 32eb5c81e5b980aa124550eb00565ca4 413 Gene3D G3DSA:3.20.20.20 4 290 6.6E-97 T 13-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 THITH_05130 32eb5c81e5b980aa124550eb00565ca4 413 PIRSF PIRSF004640 1 407 1.8E-131 T 13-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 THITH_05130 32eb5c81e5b980aa124550eb00565ca4 413 Gene3D G3DSA:3.30.413.10 291 408 1.1E-37 T 13-10-2018 THITH_01065 de0c265acd1aaa3522785041a1db4f39 77 Pfam PF04255 Protein of unknown function (DUF433) 8 62 3.3E-18 T 13-10-2018 IPR007367 Protein of unknown function DUF433 THITH_01065 de0c265acd1aaa3522785041a1db4f39 77 SUPERFAMILY SSF46689 3 72 2.51E-17 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_01065 de0c265acd1aaa3522785041a1db4f39 77 Gene3D G3DSA:1.10.10.10 7 74 5.4E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_05975 c91499b52c2e5ee8b6f4e036803e9f61 144 SUPERFAMILY SSF88723 1 125 3.64E-21 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_05975 c91499b52c2e5ee8b6f4e036803e9f61 144 Pfam PF01850 PIN domain 5 122 2.0E-11 T 13-10-2018 IPR002716 PIN domain THITH_05975 c91499b52c2e5ee8b6f4e036803e9f61 144 Gene3D G3DSA:3.40.50.1010 5 135 3.5E-8 T 13-10-2018 THITH_02805 154346387d0dadc535f6c07ed08140fb 200 SUPERFAMILY SSF52218 1 194 1.11E-57 T 13-10-2018 IPR029039 Flavoprotein-like superfamily THITH_02805 154346387d0dadc535f6c07ed08140fb 200 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 13-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 THITH_02805 154346387d0dadc535f6c07ed08140fb 200 Gene3D G3DSA:3.40.50.360 1 196 2.2E-64 T 13-10-2018 IPR029039 Flavoprotein-like superfamily THITH_02805 154346387d0dadc535f6c07ed08140fb 200 Pfam PF03358 NADPH-dependent FMN reductase 11 127 1.2E-8 T 13-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 THITH_02805 154346387d0dadc535f6c07ed08140fb 200 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 3 194 7.5E-47 T 13-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 THITH_07890 3b486d884f142b92a383ba82c1e2f5ad 291 Gene3D G3DSA:3.60.110.10 1 288 4.7E-97 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily THITH_07890 3b486d884f142b92a383ba82c1e2f5ad 291 Pfam PF00795 Carbon-nitrogen hydrolase 2 269 8.3E-60 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 THITH_07890 3b486d884f142b92a383ba82c1e2f5ad 291 SUPERFAMILY SSF56317 1 286 1.03E-86 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily THITH_13540 ed894a0a151231cbc1d5a133309d44a6 400 Gene3D G3DSA:2.40.420.20 40 381 1.6E-52 T 13-10-2018 THITH_13540 ed894a0a151231cbc1d5a133309d44a6 400 Gene3D G3DSA:2.40.50.100 55 238 1.6E-52 T 13-10-2018 THITH_13540 ed894a0a151231cbc1d5a133309d44a6 400 Pfam PF13437 HlyD family secretion protein 204 303 3.8E-6 T 13-10-2018 THITH_13540 ed894a0a151231cbc1d5a133309d44a6 400 Gene3D G3DSA:2.40.30.170 44 323 1.6E-52 T 13-10-2018 THITH_13540 ed894a0a151231cbc1d5a133309d44a6 400 SUPERFAMILY SSF111369 45 174 7.72E-8 T 13-10-2018 THITH_13540 ed894a0a151231cbc1d5a133309d44a6 400 Gene3D G3DSA:1.10.287.470 89 191 1.6E-52 T 13-10-2018 THITH_01415 fcfa20581ee69e999c7efa3c3455bcc4 622 SUPERFAMILY SSF46977 486 618 4.32E-40 T 13-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_01415 fcfa20581ee69e999c7efa3c3455bcc4 622 SUPERFAMILY SSF51905 5 477 1.9E-62 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_01415 fcfa20581ee69e999c7efa3c3455bcc4 622 Gene3D G3DSA:3.50.50.90 10 617 4.6E-260 T 13-10-2018 THITH_01415 fcfa20581ee69e999c7efa3c3455bcc4 622 TIGRFAM TIGR02061 aprA: adenylylsulfate reductase, alpha subunit 12 618 0.0 T 13-10-2018 IPR011803 Adenylylsulphate reductase, alpha subunit KEGG: 00920+1.8.99.2|MetaCyc: PWY-5278|MetaCyc: PWY-5279 THITH_01415 fcfa20581ee69e999c7efa3c3455bcc4 622 SUPERFAMILY SSF56425 239 382 2.41E-55 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_01415 fcfa20581ee69e999c7efa3c3455bcc4 622 PIRSF PIRSF000171 1 622 2.4E-237 T 13-10-2018 THITH_01415 fcfa20581ee69e999c7efa3c3455bcc4 622 Pfam PF00890 FAD binding domain 12 241 5.8E-18 T 13-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_01415 fcfa20581ee69e999c7efa3c3455bcc4 622 Pfam PF02910 Fumarate reductase flavoprotein C-term 499 613 2.5E-8 T 13-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_01415 fcfa20581ee69e999c7efa3c3455bcc4 622 Gene3D G3DSA:3.90.700.10 264 393 4.6E-260 T 13-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_10485 64a96b6edb11495b14964aef9026ed77 198 Pfam PF13511 Domain of unknown function (DUF4124) 20 69 2.7E-12 T 13-10-2018 IPR025392 Domain of unknown function DUF4124 THITH_08355 066c4013455b24468e950c96b11dd177 91 SUPERFAMILY SSF89447 12 77 1.1E-7 T 13-10-2018 IPR037914 SpoVT-AbrB domain superfamily THITH_08355 066c4013455b24468e950c96b11dd177 91 Gene3D G3DSA:2.10.260.10 7 84 6.3E-12 T 13-10-2018 THITH_16430 02a76a74587061f9a09ba9b020d42d1b 145 Gene3D G3DSA:2.60.40.10 8 112 2.8E-7 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_16950 3a28a71ef6fc1c44c63cc7174bd772fa 289 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 5 276 8.1E-42 T 13-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 THITH_16950 3a28a71ef6fc1c44c63cc7174bd772fa 289 PIRSF PIRSF026649 1 287 6.1E-71 T 13-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 THITH_05520 0b1e62133f12f027e480f4fd0768096b 331 Pfam PF00535 Glycosyl transferase family 2 7 168 3.5E-34 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THITH_05520 0b1e62133f12f027e480f4fd0768096b 331 Gene3D G3DSA:3.90.550.10 2 185 2.4E-39 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_05520 0b1e62133f12f027e480f4fd0768096b 331 SUPERFAMILY SSF53448 6 240 9.64E-41 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_17285 5df9c7b97d14c41b67df2d0786d2a685 214 Gene3D G3DSA:3.40.50.2020 2 211 4.6E-74 T 13-10-2018 THITH_17285 5df9c7b97d14c41b67df2d0786d2a685 214 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 10 185 3.7E-59 T 13-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_17285 5df9c7b97d14c41b67df2d0786d2a685 214 SUPERFAMILY SSF53271 2 207 1.66E-48 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like THITH_17285 5df9c7b97d14c41b67df2d0786d2a685 214 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 214 32.184 T 13-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 THITH_17285 5df9c7b97d14c41b67df2d0786d2a685 214 Pfam PF00156 Phosphoribosyl transferase domain 44 160 2.9E-15 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 THITH_00790 e6b97de388be1064a232e7e1da6f82d5 409 Gene3D G3DSA:3.40.50.150 46 259 2.4E-48 T 13-10-2018 THITH_00790 e6b97de388be1064a232e7e1da6f82d5 409 Pfam PF03203 MerC mercury resistance protein 289 390 6.8E-9 T 13-10-2018 IPR004891 Mercury transport protein MerC GO:0015097|GO:0015694|GO:0016020 THITH_00790 e6b97de388be1064a232e7e1da6f82d5 409 Pfam PF13847 Methyltransferase domain 76 218 7.4E-20 T 13-10-2018 IPR025714 Methyltransferase domain THITH_00790 e6b97de388be1064a232e7e1da6f82d5 409 SUPERFAMILY SSF53335 72 260 4.34E-36 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_02145 524d9a438055726a4b7249fd7b925368 302 Pfam PF12727 PBP superfamily domain 96 273 9.0E-33 T 13-10-2018 IPR024370 PBP domain THITH_02145 524d9a438055726a4b7249fd7b925368 302 Pfam PF12728 Helix-turn-helix domain 10 57 6.2E-14 T 13-10-2018 THITH_02145 524d9a438055726a4b7249fd7b925368 302 Gene3D G3DSA:1.10.1660.10 5 58 3.2E-8 T 13-10-2018 THITH_02145 524d9a438055726a4b7249fd7b925368 302 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 10 56 1.3E-15 T 13-10-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 THITH_02145 524d9a438055726a4b7249fd7b925368 302 SUPERFAMILY SSF46955 9 58 2.56E-5 T 13-10-2018 IPR009061 Putative DNA-binding domain superfamily THITH_09840 58610d5c2634efb6d770823f4bc6fa30 158 Pfam PF13884 Chaperone of endosialidase 24 73 3.9E-11 T 13-10-2018 IPR030392 Intramolecular chaperone auto-processing domain THITH_14475 cabb1ac5d2eb34b275ee6c1b541de4f5 446 Pfam PF08245 Mur ligase middle domain 116 287 2.9E-28 T 13-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 THITH_14475 cabb1ac5d2eb34b275ee6c1b541de4f5 446 Gene3D G3DSA:3.90.190.20 308 441 4.7E-43 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THITH_14475 cabb1ac5d2eb34b275ee6c1b541de4f5 446 Pfam PF02875 Mur ligase family, glutamate ligase domain 309 385 2.3E-8 T 13-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 THITH_14475 cabb1ac5d2eb34b275ee6c1b541de4f5 446 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 10 445 32.299 T 13-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THITH_14475 cabb1ac5d2eb34b275ee6c1b541de4f5 446 SUPERFAMILY SSF53244 307 445 2.41E-44 T 13-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 THITH_14475 cabb1ac5d2eb34b275ee6c1b541de4f5 446 Gene3D G3DSA:3.40.50.720 7 99 5.8E-16 T 13-10-2018 THITH_14475 cabb1ac5d2eb34b275ee6c1b541de4f5 446 SUPERFAMILY SSF53623 102 305 4.84E-49 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THITH_14475 cabb1ac5d2eb34b275ee6c1b541de4f5 446 Gene3D G3DSA:3.40.1190.10 100 307 1.5E-59 T 13-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 THITH_14475 cabb1ac5d2eb34b275ee6c1b541de4f5 446 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 12 443 1.1E-123 T 13-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 THITH_14475 cabb1ac5d2eb34b275ee6c1b541de4f5 446 SUPERFAMILY SSF51984 9 100 3.92E-13 T 13-10-2018 THITH_00995 7c1352f54ac4cba1e1722fd513b5c37a 751 Pfam PF00512 His Kinase A (phospho-acceptor) domain 292 357 5.4E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_00995 7c1352f54ac4cba1e1722fd513b5c37a 751 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 405 518 1.2E-27 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_00995 7c1352f54ac4cba1e1722fd513b5c37a 751 SUPERFAMILY SSF52172 542 667 8.68E-34 T 13-10-2018 IPR011006 CheY-like superfamily THITH_00995 7c1352f54ac4cba1e1722fd513b5c37a 751 Gene3D G3DSA:3.30.565.10 356 520 7.3E-52 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_00995 7c1352f54ac4cba1e1722fd513b5c37a 751 SMART SM00388 291 357 1.1E-19 T 13-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 THITH_00995 7c1352f54ac4cba1e1722fd513b5c37a 751 Gene3D G3DSA:3.40.50.12740 543 728 6.5E-37 T 13-10-2018 THITH_00995 7c1352f54ac4cba1e1722fd513b5c37a 751 Pfam PF11845 Protein of unknown function (DUF3365) 29 209 1.4E-27 T 13-10-2018 IPR021796 Protein of unknown function DUF3365 THITH_00995 7c1352f54ac4cba1e1722fd513b5c37a 751 SMART SM00448 543 656 1.1E-27 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_00995 7c1352f54ac4cba1e1722fd513b5c37a 751 Gene3D G3DSA:1.10.287.130 255 355 9.6E-28 T 13-10-2018 THITH_00995 7c1352f54ac4cba1e1722fd513b5c37a 751 SUPERFAMILY SSF55874 346 516 3.8E-47 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_00995 7c1352f54ac4cba1e1722fd513b5c37a 751 PRINTS PR00344 Bacterial sensor protein C-terminal signature 463 473 2.3E-20 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_00995 7c1352f54ac4cba1e1722fd513b5c37a 751 PRINTS PR00344 Bacterial sensor protein C-terminal signature 445 459 2.3E-20 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_00995 7c1352f54ac4cba1e1722fd513b5c37a 751 PRINTS PR00344 Bacterial sensor protein C-terminal signature 478 496 2.3E-20 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_00995 7c1352f54ac4cba1e1722fd513b5c37a 751 PRINTS PR00344 Bacterial sensor protein C-terminal signature 502 515 2.3E-20 T 13-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 THITH_00995 7c1352f54ac4cba1e1722fd513b5c37a 751 SUPERFAMILY SSF47384 277 358 1.9E-22 T 13-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 THITH_00995 7c1352f54ac4cba1e1722fd513b5c37a 751 SMART SM00387 404 518 8.2E-41 T 13-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase THITH_00995 7c1352f54ac4cba1e1722fd513b5c37a 751 Pfam PF00072 Response regulator receiver domain 545 655 1.5E-20 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_08190 bb3e15eb44b7966f4189416ad8e7d690 450 Gene3D G3DSA:1.20.1250.20 235 448 1.6E-61 T 13-10-2018 THITH_08190 bb3e15eb44b7966f4189416ad8e7d690 450 Pfam PF07690 Major Facilitator Superfamily 37 406 1.3E-19 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THITH_08190 bb3e15eb44b7966f4189416ad8e7d690 450 SUPERFAMILY SSF103473 26 446 4.32E-42 T 13-10-2018 IPR036259 MFS transporter superfamily THITH_08190 bb3e15eb44b7966f4189416ad8e7d690 450 Gene3D G3DSA:1.20.1250.20 1 231 2.0E-68 T 13-10-2018 THITH_07040 e23f2ae7a12cd6f14d3001dfec1c0851 386 Hamap MF_00392 Lipid-A-disaccharide synthase [lpxB]. 3 377 33.733 T 13-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 THITH_07040 e23f2ae7a12cd6f14d3001dfec1c0851 386 TIGRFAM TIGR00215 lpxB: lipid-A-disaccharide synthase 5 375 6.0E-92 T 13-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 THITH_07040 e23f2ae7a12cd6f14d3001dfec1c0851 386 SUPERFAMILY SSF53756 5 377 2.97E-31 T 13-10-2018 THITH_07040 e23f2ae7a12cd6f14d3001dfec1c0851 386 Pfam PF02684 Lipid-A-disaccharide synthetase 7 355 1.2E-96 T 13-10-2018 IPR003835 Glycosyl transferase, family 19 GO:0008915|GO:0009245 KEGG: 00540+2.4.1.182 THITH_02015 9583d1c9503b0a9120f6590c2b81dcea 262 SMART SM00852 7 167 8.0E-29 T 13-10-2018 IPR001453 MoaB/Mog domain THITH_02015 9583d1c9503b0a9120f6590c2b81dcea 262 Pfam PF00994 Probable molybdopterin binding domain 8 164 2.5E-27 T 13-10-2018 IPR001453 MoaB/Mog domain THITH_02015 9583d1c9503b0a9120f6590c2b81dcea 262 SUPERFAMILY SSF53218 6 201 1.83E-32 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily THITH_02015 9583d1c9503b0a9120f6590c2b81dcea 262 Gene3D G3DSA:3.40.980.10 5 166 3.6E-39 T 13-10-2018 IPR036425 MoaB/Mog-like domain superfamily THITH_03660 f7ec8f515188ede45dc42e652619e1c3 155 Pfam PF00583 Acetyltransferase (GNAT) family 20 127 5.4E-14 T 13-10-2018 IPR000182 GNAT domain THITH_03660 f7ec8f515188ede45dc42e652619e1c3 155 SUPERFAMILY SSF55729 9 151 1.46E-31 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_03660 f7ec8f515188ede45dc42e652619e1c3 155 Gene3D G3DSA:3.40.630.30 10 154 5.2E-41 T 13-10-2018 THITH_03660 f7ec8f515188ede45dc42e652619e1c3 155 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 18 148 5.1E-35 T 13-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 THITH_07185 096c2ec2aa88d990ef881b95ab4581f9 137 SMART SM00116 77 124 3.5E-4 T 13-10-2018 IPR000644 CBS domain THITH_07185 096c2ec2aa88d990ef881b95ab4581f9 137 SMART SM00116 10 59 9.1E-7 T 13-10-2018 IPR000644 CBS domain THITH_07185 096c2ec2aa88d990ef881b95ab4581f9 137 Gene3D G3DSA:3.10.580.10 1 135 3.8E-29 T 13-10-2018 THITH_07185 096c2ec2aa88d990ef881b95ab4581f9 137 Pfam PF00571 CBS domain 3 59 9.6E-11 T 13-10-2018 IPR000644 CBS domain THITH_07185 096c2ec2aa88d990ef881b95ab4581f9 137 Pfam PF00571 CBS domain 70 122 6.6E-7 T 13-10-2018 IPR000644 CBS domain THITH_07185 096c2ec2aa88d990ef881b95ab4581f9 137 SUPERFAMILY SSF54631 1 124 2.27E-26 T 13-10-2018 THITH_07435 2d6f2ef70f1b5b83b895ba0b7c366899 246 Pfam PF10670 Domain of unknown function (DUF4198) 17 222 6.9E-30 T 13-10-2018 IPR019613 Protein of unknown function DUF4198 THITH_10575 949446ce7393bef0508cc1aa7f2691ea 373 Pfam PF07995 Glucose / Sorbosone dehydrogenase 38 365 9.3E-129 T 13-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase THITH_10575 949446ce7393bef0508cc1aa7f2691ea 373 SUPERFAMILY SSF50952 27 368 1.44E-49 T 13-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 THITH_10575 949446ce7393bef0508cc1aa7f2691ea 373 Gene3D G3DSA:2.120.10.30 23 368 3.8E-118 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like THITH_12655 9635dca8f7d3d449fddf923a19bed831 252 Gene3D G3DSA:3.40.50.150 33 248 5.8E-16 T 13-10-2018 THITH_12655 9635dca8f7d3d449fddf923a19bed831 252 Pfam PF08241 Methyltransferase domain 86 137 1.3E-7 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 THITH_12655 9635dca8f7d3d449fddf923a19bed831 252 SUPERFAMILY SSF53335 24 235 7.74E-20 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_02195 955d15f137e7f6d90d749e97851801a7 66 Pfam PF10049 Protein of unknown function (DUF2283) 2 49 4.4E-12 T 13-10-2018 IPR019270 Protein of unknown function DUF2283 THITH_03020 adc5b59aac0745a26d5d0aafe174aeb1 312 SUPERFAMILY SSF52821 61 149 4.19E-19 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_03020 adc5b59aac0745a26d5d0aafe174aeb1 312 Pfam PF00581 Rhodanese-like domain 60 145 2.5E-12 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_03020 adc5b59aac0745a26d5d0aafe174aeb1 312 Gene3D G3DSA:3.40.250.10 46 148 4.6E-18 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_03020 adc5b59aac0745a26d5d0aafe174aeb1 312 SMART SM00450 54 150 1.3E-12 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_00455 4ab4b4a5867b00f0452353cb2f3808b0 112 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 7 92 1.6E-17 T 13-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 THITH_00455 4ab4b4a5867b00f0452353cb2f3808b0 112 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 6 89 1.2E-31 T 13-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 THITH_00455 4ab4b4a5867b00f0452353cb2f3808b0 112 Gene3D G3DSA:1.10.287.1080 2 95 1.9E-31 T 13-10-2018 THITH_00455 4ab4b4a5867b00f0452353cb2f3808b0 112 SUPERFAMILY SSF101386 4 93 3.92E-26 T 13-10-2018 THITH_00455 4ab4b4a5867b00f0452353cb2f3808b0 112 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 3 89 21.668 T 13-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 THITH_04425 40a84db63e6bb45667fa27ca3c7462fe 225 SMART SM00287 26 91 3.1E-7 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type THITH_04425 40a84db63e6bb45667fa27ca3c7462fe 225 TIGRFAM TIGR04211 SH3_and_anchor: SH3 domain protein 30 225 4.4E-58 T 13-10-2018 IPR016476 SH3 domain protein THITH_04425 40a84db63e6bb45667fa27ca3c7462fe 225 Pfam PF08239 Bacterial SH3 domain 38 87 9.8E-9 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type THITH_04425 40a84db63e6bb45667fa27ca3c7462fe 225 Gene3D G3DSA:2.30.30.40 25 89 3.4E-11 T 13-10-2018 THITH_02295 d44b06a3f2c9b2d253acc8f1a87bbb9a 70 Pfam PF11455 Protein of unknown function (DUF3018) 10 70 5.5E-21 T 13-10-2018 IPR021558 Protein of unknown function DUF3018 THITH_16360 8dbf5e16d68c0cd62b7b9892ddbd9555 287 Pfam PF01435 Peptidase family M48 80 264 2.4E-31 T 13-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 THITH_08400 42e41f1bd754cb3c0c20fce73e0d9093 642 SMART SM00327 451 640 3.1E-18 T 13-10-2018 IPR002035 von Willebrand factor, type A THITH_08400 42e41f1bd754cb3c0c20fce73e0d9093 642 SUPERFAMILY SSF53300 451 638 2.63E-20 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily THITH_08400 42e41f1bd754cb3c0c20fce73e0d9093 642 Gene3D G3DSA:3.40.50.410 448 627 1.1E-15 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily THITH_08400 42e41f1bd754cb3c0c20fce73e0d9093 642 Pfam PF00092 von Willebrand factor type A domain 454 608 4.3E-6 T 13-10-2018 IPR002035 von Willebrand factor, type A THITH_15380 318a3591aaa55fcfe06498c7b146fb90 695 Pfam PF07793 Protein of unknown function (DUF1631) 379 690 4.4E-15 T 13-10-2018 IPR012434 Protein of unknown function DUF1631 THITH_08140 effd37421d4ab0a4cbf7793f008bb672 81 Gene3D G3DSA:1.20.1640.10 1 59 2.7E-12 T 13-10-2018 THITH_08140 effd37421d4ab0a4cbf7793f008bb672 81 SUPERFAMILY SSF82866 1 49 9.68E-8 T 13-10-2018 THITH_08140 effd37421d4ab0a4cbf7793f008bb672 81 Pfam PF00873 AcrB/AcrD/AcrF family 1 44 2.8E-9 T 13-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 THITH_17290 1c6bb56f54d6e021bc48f1cee2b320f1 629 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 138 594 6.1E-214 T 13-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 THITH_17290 1c6bb56f54d6e021bc48f1cee2b320f1 629 Gene3D G3DSA:3.20.20.540 214 526 4.6E-152 T 13-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 THITH_17290 1c6bb56f54d6e021bc48f1cee2b320f1 629 Pfam PF13667 ThiC-associated domain 22 99 3.2E-32 T 13-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 THITH_17290 1c6bb56f54d6e021bc48f1cee2b320f1 629 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 138 595 98.702 T 13-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 THITH_17290 1c6bb56f54d6e021bc48f1cee2b320f1 629 Pfam PF01964 Radical SAM ThiC family 139 590 3.9E-199 T 13-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 THITH_00120 07f983a48a7febfd3c8b1b05654a48c7 168 Gene3D G3DSA:3.55.40.10 38 168 1.8E-20 T 13-10-2018 THITH_00120 07f983a48a7febfd3c8b1b05654a48c7 168 TIGRFAM TIGR01708 typeII_sec_gspH: type II secretion system protein H 6 150 3.3E-19 T 13-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 THITH_00120 07f983a48a7febfd3c8b1b05654a48c7 168 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 28 3.2E-6 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_00120 07f983a48a7febfd3c8b1b05654a48c7 168 PRINTS PR00885 Bacterial general secretion pathway protein H signature 126 141 2.1E-11 T 13-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 THITH_00120 07f983a48a7febfd3c8b1b05654a48c7 168 PRINTS PR00885 Bacterial general secretion pathway protein H signature 18 32 2.1E-11 T 13-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 THITH_00120 07f983a48a7febfd3c8b1b05654a48c7 168 PRINTS PR00885 Bacterial general secretion pathway protein H signature 3 17 2.1E-11 T 13-10-2018 IPR002416 Type II secretion system protein H GO:0008565|GO:0015627|GO:0015628 THITH_00120 07f983a48a7febfd3c8b1b05654a48c7 168 Pfam PF12019 Type II transport protein GspH 42 158 1.3E-7 T 13-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 THITH_00120 07f983a48a7febfd3c8b1b05654a48c7 168 SUPERFAMILY SSF54523 8 76 3.06E-11 T 13-10-2018 THITH_00120 07f983a48a7febfd3c8b1b05654a48c7 168 Pfam PF07963 Prokaryotic N-terminal methylation motif 5 27 6.7E-6 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_06725 dcb9838cdc6779fa3a4f48c3f5885bde 141 Gene3D G3DSA:3.30.530.20 3 139 3.9E-32 T 13-10-2018 IPR023393 START-like domain superfamily THITH_06725 dcb9838cdc6779fa3a4f48c3f5885bde 141 SUPERFAMILY SSF55961 1 134 3.73E-25 T 13-10-2018 THITH_06725 dcb9838cdc6779fa3a4f48c3f5885bde 141 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 136 1.5E-14 T 13-10-2018 IPR019587 Polyketide cyclase/dehydrase THITH_15065 00f2464293135a6d9b3640a4b48a0590 98 Pfam PF05973 Phage derived protein Gp49-like (DUF891) 13 90 4.2E-7 T 13-10-2018 IPR009241 Toxin HigB-like THITH_15065 00f2464293135a6d9b3640a4b48a0590 98 PIRSF PIRSF028744 1 98 1.4E-39 T 13-10-2018 IPR014056 Addiction module killer protein, predicted THITH_15065 00f2464293135a6d9b3640a4b48a0590 98 TIGRFAM TIGR02683 upstrm_HI1419: putative addiction module killer protein 3 95 2.4E-39 T 13-10-2018 IPR014056 Addiction module killer protein, predicted THITH_05030 e9d07489fa76d34551d89be235a00c3d 200 SUPERFAMILY SSF53335 2 180 6.66E-30 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_05030 e9d07489fa76d34551d89be235a00c3d 200 Pfam PF13649 Methyltransferase domain 39 130 3.2E-12 T 13-10-2018 THITH_05030 e9d07489fa76d34551d89be235a00c3d 200 Gene3D G3DSA:3.40.50.150 1 200 8.1E-50 T 13-10-2018 THITH_06875 bf71880f6e23e1afaf83d7f0d6939b53 304 Gene3D G3DSA:1.25.40.10 150 291 2.3E-22 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_06875 bf71880f6e23e1afaf83d7f0d6939b53 304 TIGRFAM TIGR03142 cytochro_ccmI: cytochrome c-type biogenesis protein CcmI 4 123 2.1E-27 T 13-10-2018 IPR017560 Cytochrome c-type biogenesis protein CcmI THITH_06875 bf71880f6e23e1afaf83d7f0d6939b53 304 SUPERFAMILY SSF48452 147 264 4.75E-12 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_07500 6322adfbe3b7182c6e6d1375f7dc44df 150 SUPERFAMILY SSF48695 50 150 9.11E-20 T 13-10-2018 IPR036280 Multiheme cytochrome superfamily THITH_07500 6322adfbe3b7182c6e6d1375f7dc44df 150 Pfam PF03892 Nitrate reductase cytochrome c-type subunit (NapB) 55 150 7.1E-20 T 13-10-2018 IPR005591 Nitrate reductase cytochrome c-type subunit NapB THITH_07500 6322adfbe3b7182c6e6d1375f7dc44df 150 Gene3D G3DSA:1.10.1130.10 67 138 9.1E-15 T 13-10-2018 THITH_03260 ade78ec4872c893e98714ab29ffd07d6 316 SMART SM00849 25 230 5.8E-29 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_03260 ade78ec4872c893e98714ab29ffd07d6 316 Pfam PF00753 Metallo-beta-lactamase superfamily 23 199 2.2E-21 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_03260 ade78ec4872c893e98714ab29ffd07d6 316 SUPERFAMILY SSF56281 9 263 5.11E-52 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_03260 ade78ec4872c893e98714ab29ffd07d6 316 Gene3D G3DSA:3.60.15.10 10 268 6.9E-63 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_11800 2d0aae48ea1d786a7b9aa764b72f7887 550 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 318 546 2.8E-18 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THITH_11800 2d0aae48ea1d786a7b9aa764b72f7887 550 Gene3D G3DSA:1.10.3720.10 296 543 3.5E-30 T 13-10-2018 IPR035906 MetI-like superfamily THITH_11800 2d0aae48ea1d786a7b9aa764b72f7887 550 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 283 542 1.4E-72 T 13-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 THITH_11800 2d0aae48ea1d786a7b9aa764b72f7887 550 SUPERFAMILY SSF161098 280 532 4.97E-35 T 13-10-2018 IPR035906 MetI-like superfamily THITH_08655 538ae1f958108b21617008a1ea436c93 159 Gene3D G3DSA:3.40.250.10 1 130 1.9E-26 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_08655 538ae1f958108b21617008a1ea436c93 159 SMART SM00450 19 124 7.1E-22 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_08655 538ae1f958108b21617008a1ea436c93 159 SUPERFAMILY SSF52821 8 131 3.14E-29 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_08655 538ae1f958108b21617008a1ea436c93 159 Pfam PF00581 Rhodanese-like domain 23 119 8.4E-15 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_05870 3d3b4480a3ae74a4824291a3c5dcd22c 178 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 9 61 5.5E-7 T 13-10-2018 IPR025159 Transcriptional regulator, AbiEi antitoxin THITH_14075 5b4a5bf82706062f9d281e552dfba728 374 SUPERFAMILY SSF52096 58 349 1.59E-33 T 13-10-2018 IPR029045 ClpP/crotonase-like domain superfamily THITH_14075 5b4a5bf82706062f9d281e552dfba728 374 SUPERFAMILY SSF50156 105 173 1.21E-9 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 THITH_14075 5b4a5bf82706062f9d281e552dfba728 374 SMART SM00245 158 345 7.1E-22 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 THITH_14075 5b4a5bf82706062f9d281e552dfba728 374 Pfam PF03572 Peptidase family S41 184 343 9.1E-29 T 13-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 THITH_14075 5b4a5bf82706062f9d281e552dfba728 374 Gene3D G3DSA:3.90.226.10 171 342 3.1E-45 T 13-10-2018 THITH_14075 5b4a5bf82706062f9d281e552dfba728 374 Gene3D G3DSA:2.30.42.10 86 170 3.1E-45 T 13-10-2018 THITH_14075 5b4a5bf82706062f9d281e552dfba728 374 Gene3D G3DSA:3.30.750.44 306 320 3.1E-45 T 13-10-2018 THITH_13160 917a64ab05283bbd185152f15e9c79d6 116 Pfam PF03658 RnfH family Ubiquitin 13 95 5.5E-35 T 13-10-2018 IPR005346 RnfH protein THITH_13160 917a64ab05283bbd185152f15e9c79d6 116 SUPERFAMILY SSF54285 12 87 9.16E-26 T 13-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp THITH_13160 917a64ab05283bbd185152f15e9c79d6 116 Hamap MF_00460 Protein RnfH [rnfH]. 13 103 25.95 T 13-10-2018 IPR005346 RnfH protein THITH_13160 917a64ab05283bbd185152f15e9c79d6 116 Gene3D G3DSA:3.10.20.280 1 97 1.6E-34 T 13-10-2018 IPR037021 RnfH superfamily THITH_09345 f57afa13ad19f3ce24b7fb1554ea5dec 236 TIGRFAM TIGR02582 cas7_TM1809: CRISPR type III-A/MTUBE-associated RAMP protein Csm3 8 217 3.8E-63 T 13-10-2018 IPR013412 CRISPR-associated RAMP Csm3 THITH_09345 f57afa13ad19f3ce24b7fb1554ea5dec 236 Pfam PF03787 RAMP superfamily 13 216 2.6E-10 T 13-10-2018 IPR005537 CRISPR type III-associated RAMP protein THITH_07355 a07c2ba48bfd61fa99f0e08b96c8b415 467 SUPERFAMILY SSF52540 3 167 6.55E-18 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_07355 a07c2ba48bfd61fa99f0e08b96c8b415 467 Gene3D G3DSA:3.40.50.300 2 197 1.6E-23 T 13-10-2018 THITH_07355 a07c2ba48bfd61fa99f0e08b96c8b415 467 Pfam PF01926 50S ribosome-binding GTPase 6 137 1.0E-13 T 13-10-2018 IPR006073 GTP binding domain GO:0005525 THITH_07355 a07c2ba48bfd61fa99f0e08b96c8b415 467 Pfam PF11981 Domain of unknown function (DUF3482) 165 454 6.1E-92 T 13-10-2018 IPR021871 Protein of unknown function DUF3482 THITH_00460 78fe0e644b8d08fae63c1940cb7f76ca 262 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 255 48.395 T 13-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 THITH_00460 78fe0e644b8d08fae63c1940cb7f76ca 262 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 255 1.4E-114 T 13-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 THITH_00460 78fe0e644b8d08fae63c1940cb7f76ca 262 Pfam PF00977 Histidine biosynthesis protein 5 238 9.9E-90 T 13-10-2018 IPR006062 Histidine biosynthesis GO:0000105 THITH_00460 78fe0e644b8d08fae63c1940cb7f76ca 262 Gene3D G3DSA:3.20.20.70 1 260 6.7E-109 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_00460 78fe0e644b8d08fae63c1940cb7f76ca 262 SUPERFAMILY SSF51366 1 255 7.46E-82 T 13-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 THITH_14700 aecf11282290dd7e2e70c11adea90e68 312 Gene3D G3DSA:1.20.1530.20 164 309 5.1E-8 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily THITH_14700 aecf11282290dd7e2e70c11adea90e68 312 Pfam PF03547 Membrane transport protein 161 302 4.6E-19 T 13-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 THITH_14700 aecf11282290dd7e2e70c11adea90e68 312 Pfam PF03547 Membrane transport protein 12 137 1.8E-8 T 13-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 THITH_09395 1761e1bb22d98aa9a064208b90798e3b 164 Gene3D G3DSA:3.90.950.20 1 160 1.1E-57 T 13-10-2018 IPR036653 CinA-like, C-terminal THITH_09395 1761e1bb22d98aa9a064208b90798e3b 164 Pfam PF02464 Competence-damaged protein 8 158 1.1E-53 T 13-10-2018 IPR008136 CinA, C-terminal THITH_09395 1761e1bb22d98aa9a064208b90798e3b 164 SUPERFAMILY SSF142433 7 159 5.36E-53 T 13-10-2018 IPR036653 CinA-like, C-terminal THITH_09395 1761e1bb22d98aa9a064208b90798e3b 164 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 12 157 2.3E-46 T 13-10-2018 IPR008136 CinA, C-terminal THITH_12295 ab6b431b1d322459b987f0d2183aa721 142 Pfam PF02657 Fe-S metabolism associated domain 8 132 4.6E-41 T 13-10-2018 IPR003808 Fe-S metabolism associated domain, SufE-like THITH_12295 ab6b431b1d322459b987f0d2183aa721 142 Gene3D G3DSA:3.90.1010.10 1 141 3.9E-47 T 13-10-2018 THITH_12295 ab6b431b1d322459b987f0d2183aa721 142 SUPERFAMILY SSF82649 2 137 4.87E-40 T 13-10-2018 THITH_02055 8ccd57e341cdbeb8bc2beaad549fe7ee 233 SUPERFAMILY SSF161098 7 223 2.88E-33 T 13-10-2018 IPR035906 MetI-like superfamily THITH_02055 8ccd57e341cdbeb8bc2beaad549fe7ee 233 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 219 2.9E-8 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THITH_02055 8ccd57e341cdbeb8bc2beaad549fe7ee 233 Gene3D G3DSA:1.10.3720.10 3 228 6.0E-27 T 13-10-2018 IPR035906 MetI-like superfamily THITH_09275 cdbec2b8dad953d4561c0d5d585b577d 376 Pfam PF03787 RAMP superfamily 80 247 5.2E-7 T 13-10-2018 IPR005537 CRISPR type III-associated RAMP protein THITH_11640 0896a58b8523b2f8eb28208bd7322074 177 Pfam PF01569 PAP2 superfamily 62 170 3.7E-21 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THITH_11640 0896a58b8523b2f8eb28208bd7322074 177 SMART SM00014 58 167 8.1E-16 T 13-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase THITH_11640 0896a58b8523b2f8eb28208bd7322074 177 Gene3D G3DSA:1.20.144.10 57 168 1.8E-19 T 13-10-2018 THITH_11640 0896a58b8523b2f8eb28208bd7322074 177 SUPERFAMILY SSF48317 4 171 1.44E-38 T 13-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily THITH_03715 c004608af6a3162fcda74d780c3896eb 74 Pfam PF04255 Protein of unknown function (DUF433) 7 62 1.3E-27 T 13-10-2018 IPR007367 Protein of unknown function DUF433 THITH_03715 c004608af6a3162fcda74d780c3896eb 74 Gene3D G3DSA:1.10.10.10 6 69 3.7E-21 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_03715 c004608af6a3162fcda74d780c3896eb 74 SUPERFAMILY SSF46689 4 67 1.49E-23 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_16425 4820beb1ea5e8b40b1a811a1ea31720d 482 Pfam PF00474 Sodium:solute symporter family 42 427 5.3E-26 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 THITH_16425 4820beb1ea5e8b40b1a811a1ea31720d 482 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 409 429 - T 13-10-2018 IPR018212 Sodium/solute symporter, conserved site THITH_16425 4820beb1ea5e8b40b1a811a1ea31720d 482 Gene3D G3DSA:1.20.1730.10 32 470 1.7E-55 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily THITH_16425 4820beb1ea5e8b40b1a811a1ea31720d 482 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 157 182 - T 13-10-2018 IPR018212 Sodium/solute symporter, conserved site THITH_10015 a7d59c9df828c03dadfc1a3b32a362eb 242 Pfam PF04402 Protein of unknown function (DUF541) 31 226 2.9E-25 T 13-10-2018 IPR007497 Protein of unknown function DUF541 THITH_10015 a7d59c9df828c03dadfc1a3b32a362eb 242 Gene3D G3DSA:3.30.70.2970 42 147 4.2E-19 T 13-10-2018 THITH_10015 a7d59c9df828c03dadfc1a3b32a362eb 242 Gene3D G3DSA:3.30.110.170 32 225 4.2E-19 T 13-10-2018 THITH_15430 11cc329c127fc60f399ac61fdb824385 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 54 2.0E-11 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THITH_15430 11cc329c127fc60f399ac61fdb824385 192 Pfam PF16925 Bacterial transcriptional repressor C-terminal 77 188 5.2E-33 T 13-10-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal THITH_15430 11cc329c127fc60f399ac61fdb824385 192 SUPERFAMILY SSF46689 4 71 1.74E-15 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_15430 11cc329c127fc60f399ac61fdb824385 192 SUPERFAMILY SSF48498 77 186 2.88E-25 T 13-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily THITH_15430 11cc329c127fc60f399ac61fdb824385 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 4.3E-5 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THITH_15430 11cc329c127fc60f399ac61fdb824385 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 4.3E-5 T 13-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 THITH_15430 11cc329c127fc60f399ac61fdb824385 192 Gene3D G3DSA:1.10.357.10 3 192 6.7E-58 T 13-10-2018 THITH_04480 28582f46764c73062a1146c1c65bc653 324 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_04480 28582f46764c73062a1146c1c65bc653 324 Gene3D G3DSA:3.40.50.300 4 323 1.5E-90 T 13-10-2018 THITH_04480 28582f46764c73062a1146c1c65bc653 324 Pfam PF00005 ABC transporter 27 184 2.2E-25 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_04480 28582f46764c73062a1146c1c65bc653 324 SUPERFAMILY SSF52540 6 254 2.72E-61 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_04480 28582f46764c73062a1146c1c65bc653 324 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 317 7.5E-25 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THITH_04480 28582f46764c73062a1146c1c65bc653 324 SMART SM00382 35 241 1.3E-15 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_04480 28582f46764c73062a1146c1c65bc653 324 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 298 2.2E-19 T 13-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 THITH_08685 c68ba9f533066d2f1ff82f41fbc931da 284 Gene3D G3DSA:1.10.3720.10 85 280 4.3E-38 T 13-10-2018 IPR035906 MetI-like superfamily THITH_08685 c68ba9f533066d2f1ff82f41fbc931da 284 SUPERFAMILY SSF161098 89 275 6.93E-42 T 13-10-2018 IPR035906 MetI-like superfamily THITH_08685 c68ba9f533066d2f1ff82f41fbc931da 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 269 2.8E-23 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THITH_08185 5148ec81e14295f3485d2070ee28f832 533 SUPERFAMILY SSF103473 22 527 1.96E-27 T 13-10-2018 IPR036259 MFS transporter superfamily THITH_08185 5148ec81e14295f3485d2070ee28f832 533 Gene3D G3DSA:1.20.1250.20 308 532 3.4E-62 T 13-10-2018 THITH_08185 5148ec81e14295f3485d2070ee28f832 533 Gene3D G3DSA:1.20.1250.20 1 238 1.1E-76 T 13-10-2018 THITH_08185 5148ec81e14295f3485d2070ee28f832 533 Pfam PF07690 Major Facilitator Superfamily 36 489 2.0E-10 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THITH_10530 2277a9133982567a7d8023512fe70bf9 831 Pfam PF02687 FtsX-like permease family 734 822 3.2E-6 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THITH_09865 1ee9002db1929e8b5e6ca17a23293796 317 SMART SM01126 137 283 5.1E-37 T 13-10-2018 IPR024445 ISXO2-like transposase domain THITH_09865 1ee9002db1929e8b5e6ca17a23293796 317 Pfam PF12760 Transposase zinc-ribbon domain 23 69 5.8E-15 T 13-10-2018 IPR024442 Transposase, zinc-ribbon THITH_09865 1ee9002db1929e8b5e6ca17a23293796 317 Pfam PF12762 ISXO2-like transposase domain 138 283 5.9E-30 T 13-10-2018 IPR024445 ISXO2-like transposase domain THITH_01090 0ee7ebeaaea1e71d510cf8ddb5b20d03 297 SUPERFAMILY SSF56235 1 212 3.94E-64 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_01090 0ee7ebeaaea1e71d510cf8ddb5b20d03 297 Gene3D G3DSA:3.60.20.10 1 218 1.5E-74 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_01090 0ee7ebeaaea1e71d510cf8ddb5b20d03 297 Pfam PF06267 Family of unknown function (DUF1028) 2 196 8.5E-67 T 13-10-2018 IPR010430 Protein of unknown function DUF1028 THITH_15570 af70b43fa66c0ceacd14b0449ca033aa 193 Pfam PF14334 Domain of unknown function (DUF4390) 30 191 1.1E-33 T 13-10-2018 IPR025500 Protein of unknown function DUF4390 THITH_10370 793b48c64ec402994f2a7b2aa6ed392c 410 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 22 410 42.517 T 13-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10370 793b48c64ec402994f2a7b2aa6ed392c 410 SUPERFAMILY SSF56762 36 410 5.36E-116 T 13-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10370 793b48c64ec402994f2a7b2aa6ed392c 410 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 27 410 1.5E-145 T 13-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10370 793b48c64ec402994f2a7b2aa6ed392c 410 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 141 410 4.8E-106 T 13-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10370 793b48c64ec402994f2a7b2aa6ed392c 410 Gene3D G3DSA:1.10.645.20 25 410 4.1E-153 T 13-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_09680 9d21c3b951e34cb91a300e15899b914b 427 Gene3D G3DSA:1.20.1250.20 6 204 3.3E-12 T 13-10-2018 THITH_09680 9d21c3b951e34cb91a300e15899b914b 427 Gene3D G3DSA:1.20.1250.20 226 425 4.8E-19 T 13-10-2018 THITH_09680 9d21c3b951e34cb91a300e15899b914b 427 Pfam PF07690 Major Facilitator Superfamily 45 316 3.9E-19 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THITH_09680 9d21c3b951e34cb91a300e15899b914b 427 SUPERFAMILY SSF103473 7 423 2.22E-39 T 13-10-2018 IPR036259 MFS transporter superfamily THITH_02925 f2e1c9059b9b31355f63f027a3ad7e34 431 Hamap MF_00671 Tol-Pal system protein TolB [tolB]. 6 428 42.492 T 13-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 THITH_02925 f2e1c9059b9b31355f63f027a3ad7e34 431 Gene3D G3DSA:3.40.50.10070 24 165 1.9E-38 T 13-10-2018 IPR036752 TolB, N-terminal domain superfamily GO:0015031|GO:0042597 THITH_02925 f2e1c9059b9b31355f63f027a3ad7e34 431 TIGRFAM TIGR02800 propeller_TolB: Tol-Pal system beta propeller repeat protein TolB 16 429 1.5E-140 T 13-10-2018 IPR014167 Tol-Pal system protein TolB GO:0017038|GO:0042597 THITH_02925 f2e1c9059b9b31355f63f027a3ad7e34 431 Pfam PF07676 WD40-like Beta Propeller Repeat 330 351 0.0023 T 13-10-2018 IPR011659 WD40-like Beta Propeller THITH_02925 f2e1c9059b9b31355f63f027a3ad7e34 431 Pfam PF07676 WD40-like Beta Propeller Repeat 376 396 0.29 T 13-10-2018 IPR011659 WD40-like Beta Propeller THITH_02925 f2e1c9059b9b31355f63f027a3ad7e34 431 Pfam PF07676 WD40-like Beta Propeller Repeat 282 318 2.1E-13 T 13-10-2018 IPR011659 WD40-like Beta Propeller THITH_02925 f2e1c9059b9b31355f63f027a3ad7e34 431 Pfam PF07676 WD40-like Beta Propeller Repeat 197 229 0.0021 T 13-10-2018 IPR011659 WD40-like Beta Propeller THITH_02925 f2e1c9059b9b31355f63f027a3ad7e34 431 Pfam PF07676 WD40-like Beta Propeller Repeat 240 274 1.4E-7 T 13-10-2018 IPR011659 WD40-like Beta Propeller THITH_02925 f2e1c9059b9b31355f63f027a3ad7e34 431 SUPERFAMILY SSF52964 30 162 1.22E-33 T 13-10-2018 THITH_02925 f2e1c9059b9b31355f63f027a3ad7e34 431 Pfam PF04052 TolB amino-terminal domain 25 130 1.2E-25 T 13-10-2018 IPR007195 TolB, N-terminal GO:0015031|GO:0042597 THITH_02925 f2e1c9059b9b31355f63f027a3ad7e34 431 Gene3D G3DSA:2.120.10.30 166 431 3.0E-88 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like THITH_02925 f2e1c9059b9b31355f63f027a3ad7e34 431 SUPERFAMILY SSF69304 155 430 8.63E-57 T 13-10-2018 THITH_05100 1a893a5dab9ce88a3befae6713f9ce8d 328 Pfam PF16868 NMT1-like family 35 322 4.4E-88 T 13-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family THITH_05100 1a893a5dab9ce88a3befae6713f9ce8d 328 Gene3D G3DSA:3.40.190.10 122 260 5.7E-101 T 13-10-2018 THITH_05100 1a893a5dab9ce88a3befae6713f9ce8d 328 Gene3D G3DSA:3.40.190.10 35 322 5.7E-101 T 13-10-2018 THITH_05100 1a893a5dab9ce88a3befae6713f9ce8d 328 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 15 323 1.3E-97 T 13-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family THITH_05100 1a893a5dab9ce88a3befae6713f9ce8d 328 SUPERFAMILY SSF53850 30 322 4.97E-82 T 13-10-2018 THITH_15900 762cd3737156397ddfc764dbeca8bdd2 208 SUPERFAMILY SSF53335 25 195 8.44E-34 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_15900 762cd3737156397ddfc764dbeca8bdd2 208 Pfam PF05175 Methyltransferase small domain 36 200 3.2E-33 T 13-10-2018 IPR007848 Methyltransferase small domain GO:0008168 THITH_15900 762cd3737156397ddfc764dbeca8bdd2 208 Gene3D G3DSA:3.40.50.150 26 206 3.1E-41 T 13-10-2018 THITH_07905 28481b76ee1709aad88f07e5378ad74f 416 Pfam PF12704 MacB-like periplasmic core domain 27 213 4.8E-15 T 13-10-2018 IPR025857 MacB-like periplasmic core domain THITH_07905 28481b76ee1709aad88f07e5378ad74f 416 Pfam PF02687 FtsX-like permease family 302 409 6.0E-13 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THITH_07905 28481b76ee1709aad88f07e5378ad74f 416 TIGRFAM TIGR02212 lolCE: lipoprotein releasing system, transmembrane protein, LolC/E family 4 416 1.4E-153 T 13-10-2018 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E GO:0016021|GO:0042953|GO:0042954 THITH_06125 7d62e863935c221acadf45dd6794d936 233 Gene3D G3DSA:3.40.50.150 67 223 7.2E-16 T 13-10-2018 THITH_06125 7d62e863935c221acadf45dd6794d936 233 Pfam PF13489 Methyltransferase domain 80 217 4.7E-22 T 13-10-2018 THITH_06125 7d62e863935c221acadf45dd6794d936 233 SUPERFAMILY SSF53335 78 220 3.27E-22 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_05065 0649b7d6f5ed32f5e8a9e5098c8ef631 196 Pfam PF09837 Uncharacterized protein conserved in bacteria (DUF2064) 40 155 1.3E-24 T 13-10-2018 IPR018641 Transferase 1, rSAM/selenodomain-associated THITH_05065 0649b7d6f5ed32f5e8a9e5098c8ef631 196 TIGRFAM TIGR04282 glyco_like_cofC: transferase 1, rSAM/selenodomain-associated 3 188 4.1E-55 T 13-10-2018 IPR018641 Transferase 1, rSAM/selenodomain-associated THITH_05065 0649b7d6f5ed32f5e8a9e5098c8ef631 196 SUPERFAMILY SSF53448 5 192 2.22E-31 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_05065 0649b7d6f5ed32f5e8a9e5098c8ef631 196 Gene3D G3DSA:3.90.550.10 1 195 5.8E-56 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_02995 acff5df00972e60bb0db0ca45466feb6 494 SUPERFAMILY SSF52025 128 200 8.11E-11 T 13-10-2018 THITH_02995 acff5df00972e60bb0db0ca45466feb6 494 Pfam PF02225 PA domain 386 474 3.7E-13 T 13-10-2018 IPR003137 PA domain THITH_02995 acff5df00972e60bb0db0ca45466feb6 494 Pfam PF02225 PA domain 127 191 1.0E-11 T 13-10-2018 IPR003137 PA domain THITH_02995 acff5df00972e60bb0db0ca45466feb6 494 Pfam PF02225 PA domain 243 331 3.8E-14 T 13-10-2018 IPR003137 PA domain THITH_02995 acff5df00972e60bb0db0ca45466feb6 494 Gene3D G3DSA:3.50.30.30 353 489 1.3E-30 T 13-10-2018 THITH_02995 acff5df00972e60bb0db0ca45466feb6 494 Gene3D G3DSA:3.50.30.30 208 352 6.9E-33 T 13-10-2018 THITH_02995 acff5df00972e60bb0db0ca45466feb6 494 Gene3D G3DSA:3.50.30.30 71 205 5.4E-29 T 13-10-2018 THITH_02995 acff5df00972e60bb0db0ca45466feb6 494 SUPERFAMILY SSF52025 384 486 4.97E-12 T 13-10-2018 THITH_02995 acff5df00972e60bb0db0ca45466feb6 494 SUPERFAMILY SSF52025 239 338 6.02E-13 T 13-10-2018 THITH_09925 260c9887bcb393a133bc40ff6b7c8bf5 329 TIGRFAM TIGR04267 mod_HExxH: HEXXH motif domain 137 316 1.3E-16 T 13-10-2018 IPR026337 HEXXH motif domain THITH_04915 80de03b5a1c562da8952040ef5014a98 359 Gene3D G3DSA:3.30.470.20 104 354 4.1E-10 T 13-10-2018 THITH_04915 80de03b5a1c562da8952040ef5014a98 359 SUPERFAMILY SSF56059 107 297 6.3E-17 T 13-10-2018 THITH_14680 30e334897d60ffe41a68d26e15daca27 293 PIRSF PIRSF005052 1 288 6.7E-105 T 13-10-2018 IPR005337 RapZ-like family GO:0005524 THITH_14680 30e334897d60ffe41a68d26e15daca27 293 Pfam PF03668 P-loop ATPase protein family 1 286 1.7E-88 T 13-10-2018 IPR005337 RapZ-like family GO:0005524 THITH_14680 30e334897d60ffe41a68d26e15daca27 293 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 287 38.674 T 13-10-2018 IPR005337 RapZ-like family GO:0005524 THITH_14680 30e334897d60ffe41a68d26e15daca27 293 SUPERFAMILY SSF52540 1 156 2.92E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_05345 ceba759f0d3787c12689b52007394ca7 219 Pfam PF01794 Ferric reductase like transmembrane component 57 170 6.6E-13 T 13-10-2018 IPR013130 Ferric reductase transmembrane component-like domain THITH_05345 ceba759f0d3787c12689b52007394ca7 219 Hamap MF_01207 Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ [msrQ]. 10 209 19.722 T 13-10-2018 IPR022837 Protein-methionine-sulfoxide reductase subunit MsrQ GO:0005887|GO:0030091 THITH_06800 3f5c21a3d3394075608b4bfbe4c5243c 455 Gene3D G3DSA:3.40.50.300 219 429 7.6E-62 T 13-10-2018 THITH_06800 3f5c21a3d3394075608b4bfbe4c5243c 455 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 211 421 1.4E-90 T 13-10-2018 IPR004392 Hydrogenase maturation factor HypB GO:0016151|GO:0051604 THITH_06800 3f5c21a3d3394075608b4bfbe4c5243c 455 SUPERFAMILY SSF52540 216 422 3.42E-36 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_06800 3f5c21a3d3394075608b4bfbe4c5243c 455 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 239 401 8.1E-36 T 13-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain THITH_03480 aa1fc9aa03e1e22e7370a68acf46670d 344 PIRSF PIRSF038991 1 340 2.8E-73 T 13-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 THITH_03480 aa1fc9aa03e1e22e7370a68acf46670d 344 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 2 151 3.5E-32 T 13-10-2018 IPR017516 AbrB duplication THITH_03480 aa1fc9aa03e1e22e7370a68acf46670d 344 TIGRFAM TIGR03082 Gneg_AbrB_dup: membrane protein AbrB duplication 176 328 2.1E-28 T 13-10-2018 IPR017516 AbrB duplication THITH_03480 aa1fc9aa03e1e22e7370a68acf46670d 344 Pfam PF05145 Transition state regulatory protein AbrB 20 328 5.1E-80 T 13-10-2018 IPR007820 AbrB family GO:0010468|GO:0016021 THITH_10135 fb4861d8e222d4304e82b570d65c18c2 294 Pfam PF13632 Glycosyl transferase family group 2 178 286 1.4E-6 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THITH_10135 fb4861d8e222d4304e82b570d65c18c2 294 Gene3D G3DSA:3.90.550.10 1 241 2.7E-45 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_10135 fb4861d8e222d4304e82b570d65c18c2 294 SUPERFAMILY SSF53448 2 273 6.0E-55 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_10135 fb4861d8e222d4304e82b570d65c18c2 294 Pfam PF00535 Glycosyl transferase family 2 7 139 7.3E-22 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THITH_04165 69af91d8ca5cc92c4540c864c5626cfd 252 Pfam PF01925 Sulfite exporter TauE/SafE 13 243 4.4E-23 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 THITH_11700 92a5e474516da9137c005b7d27c5c546 119 Gene3D G3DSA:3.40.250.10 1 109 2.9E-20 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_11700 92a5e474516da9137c005b7d27c5c546 119 SMART SM00450 1 106 9.2E-9 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_11700 92a5e474516da9137c005b7d27c5c546 119 Pfam PF00581 Rhodanese-like domain 4 102 1.9E-13 T 13-10-2018 IPR001763 Rhodanese-like domain THITH_11700 92a5e474516da9137c005b7d27c5c546 119 SUPERFAMILY SSF52821 2 110 2.49E-20 T 13-10-2018 IPR036873 Rhodanese-like domain superfamily THITH_14250 21ed86b16180a2c0c925617b7ad409aa 64 Gene3D G3DSA:1.10.287.310 1 63 1.1E-23 T 13-10-2018 THITH_14250 21ed86b16180a2c0c925617b7ad409aa 64 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 16.208 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14250 21ed86b16180a2c0c925617b7ad409aa 64 Pfam PF00831 Ribosomal L29 protein 5 60 8.4E-22 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14250 21ed86b16180a2c0c925617b7ad409aa 64 SUPERFAMILY SSF46561 1 62 1.96E-19 T 13-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14250 21ed86b16180a2c0c925617b7ad409aa 64 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 1.1E-19 T 13-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_10540 c8e7de871141145cf785a3b0327ff7cb 662 Gene3D G3DSA:2.160.20.80 61 184 1.5E-27 T 13-10-2018 THITH_10540 c8e7de871141145cf785a3b0327ff7cb 662 SUPERFAMILY SSF141571 63 166 1.22E-26 T 13-10-2018 THITH_10540 c8e7de871141145cf785a3b0327ff7cb 662 Pfam PF00805 Pentapeptide repeats (8 copies) 64 103 6.9E-13 T 13-10-2018 IPR001646 Pentapeptide repeat THITH_10540 c8e7de871141145cf785a3b0327ff7cb 662 Pfam PF00805 Pentapeptide repeats (8 copies) 124 161 5.6E-5 T 13-10-2018 IPR001646 Pentapeptide repeat THITH_10215 7dd94f2bc1179841abc9c8bb5fbf474f 358 SUPERFAMILY SSF51735 1 350 6.33E-92 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_10215 7dd94f2bc1179841abc9c8bb5fbf474f 358 Gene3D G3DSA:3.90.25.10 202 338 1.5E-127 T 13-10-2018 THITH_10215 7dd94f2bc1179841abc9c8bb5fbf474f 358 Pfam PF16363 GDP-mannose 4,6 dehydratase 6 330 7.3E-92 T 13-10-2018 IPR016040 NAD(P)-binding domain THITH_10215 7dd94f2bc1179841abc9c8bb5fbf474f 358 Gene3D G3DSA:3.40.50.720 5 330 1.5E-127 T 13-10-2018 THITH_10215 7dd94f2bc1179841abc9c8bb5fbf474f 358 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 5 345 1.7E-146 T 13-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 THITH_13025 e75a54fadf2b1f990da4f6a032956685 208 Pfam PF01728 FtsJ-like methyltransferase 29 204 2.1E-57 T 13-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 THITH_13025 e75a54fadf2b1f990da4f6a032956685 208 PIRSF PIRSF005461 1 208 3.6E-77 T 13-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 THITH_13025 e75a54fadf2b1f990da4f6a032956685 208 Gene3D G3DSA:3.40.50.150 28 208 2.7E-60 T 13-10-2018 THITH_13025 e75a54fadf2b1f990da4f6a032956685 208 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 13 206 29.728 T 13-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 THITH_13025 e75a54fadf2b1f990da4f6a032956685 208 SUPERFAMILY SSF53335 28 205 1.75E-42 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_04510 be442db0dbc756ec67f34f14d16f5c56 266 Gene3D G3DSA:1.10.287.1080 132 264 2.4E-44 T 13-10-2018 THITH_04510 be442db0dbc756ec67f34f14d16f5c56 266 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 30 103 1.3E-25 T 13-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core THITH_04510 be442db0dbc756ec67f34f14d16f5c56 266 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 165 228 4.5E-7 T 13-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core THITH_04510 be442db0dbc756ec67f34f14d16f5c56 266 TIGRFAM TIGR00444 mazG: MazG family protein 13 259 1.2E-91 T 13-10-2018 IPR011551 NTP pyrophosphohydrolase MazG THITH_04510 be442db0dbc756ec67f34f14d16f5c56 266 SUPERFAMILY SSF101386 139 238 5.05E-24 T 13-10-2018 THITH_04510 be442db0dbc756ec67f34f14d16f5c56 266 Gene3D G3DSA:1.10.287.1080 5 127 4.1E-44 T 13-10-2018 THITH_04510 be442db0dbc756ec67f34f14d16f5c56 266 SUPERFAMILY SSF101386 7 106 5.98E-23 T 13-10-2018 THITH_04455 93f4db4da4138e602c4ff14656622175 91 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 31 83 1.2E-17 T 13-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 THITH_04455 93f4db4da4138e602c4ff14656622175 91 PIRSF PIRSF028784 1 91 4.4E-27 T 13-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 THITH_16030 89564962128a641c4eb6d4aa1fcb5637 376 Pfam PF00437 Type II/IV secretion system protein 11 256 2.1E-33 T 13-10-2018 IPR001482 Type II/IV secretion system protein THITH_16030 89564962128a641c4eb6d4aa1fcb5637 376 Gene3D G3DSA:3.40.50.300 105 352 4.0E-86 T 13-10-2018 THITH_16030 89564962128a641c4eb6d4aa1fcb5637 376 Gene3D G3DSA:3.30.450.90 1 102 4.0E-28 T 13-10-2018 THITH_16030 89564962128a641c4eb6d4aa1fcb5637 376 SUPERFAMILY SSF52540 4 338 3.34E-65 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_16030 89564962128a641c4eb6d4aa1fcb5637 376 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 6 345 4.0E-127 T 13-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 THITH_16075 8b9ca1548d5d6ebbd12d3ddc1472f061 227 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 9 183 1.7E-7 T 13-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 THITH_16075 8b9ca1548d5d6ebbd12d3ddc1472f061 227 Gene3D G3DSA:3.40.50.1000 5 195 2.1E-20 T 13-10-2018 IPR023214 HAD superfamily THITH_16075 8b9ca1548d5d6ebbd12d3ddc1472f061 227 Pfam PF12710 haloacid dehalogenase-like hydrolase 9 149 1.3E-7 T 13-10-2018 THITH_16075 8b9ca1548d5d6ebbd12d3ddc1472f061 227 SUPERFAMILY SSF56784 3 213 7.74E-34 T 13-10-2018 IPR036412 HAD-like superfamily THITH_06295 cd7db13f984977c9818dee49d2f9b01c 733 Pfam PF04453 Organic solvent tolerance protein 291 649 1.1E-86 T 13-10-2018 IPR007543 Organic solvent tolerance protein, C-terminal GO:0010033|GO:0019867|GO:0061024 THITH_06295 cd7db13f984977c9818dee49d2f9b01c 733 Hamap MF_01411 LPS-assembly protein LptD [lptD]. 7 711 18.74 T 13-10-2018 IPR020889 LPS-assembly protein LptD GO:0009279|GO:0010033|GO:0015920|GO:0043165 THITH_14645 4cc9b1a5217e5f06a67d3e6b1151c046 186 TIGRFAM TIGR04409 LptC_YrbK: LPS export ABC transporter periplasmic protein LptC 37 181 1.3E-23 T 13-10-2018 IPR026265 Lipopolysaccharide export system protein LptC GO:0005887|GO:0015221|GO:0015920 THITH_14645 4cc9b1a5217e5f06a67d3e6b1151c046 186 Gene3D G3DSA:2.60.450.10 57 186 2.8E-6 T 13-10-2018 THITH_14645 4cc9b1a5217e5f06a67d3e6b1151c046 186 Pfam PF06835 Lipopolysaccharide-assembly, LptC-related 40 182 1.4E-19 T 13-10-2018 IPR010664 Lipopolysaccharide assembly, LptC-related THITH_00940 56a0a175b40d7cdb7c95e883117fc945 175 Pfam PF02635 DsrE/DsrF-like family 71 173 1.7E-8 T 13-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein THITH_00940 56a0a175b40d7cdb7c95e883117fc945 175 SUPERFAMILY SSF75169 42 172 1.1E-16 T 13-10-2018 IPR027396 DsrEFH-like THITH_00940 56a0a175b40d7cdb7c95e883117fc945 175 Gene3D G3DSA:3.40.1260.10 40 173 1.7E-18 T 13-10-2018 IPR027396 DsrEFH-like THITH_17120 c0bca6df7735c3ef4e7b14c7a5616f96 108 Pfam PF13511 Domain of unknown function (DUF4124) 15 60 4.1E-11 T 13-10-2018 IPR025392 Domain of unknown function DUF4124 THITH_12410 7d766b8083f68c31835a472ec4ddcfac 181 Pfam PF07152 YaeQ protein 1 172 2.5E-71 T 13-10-2018 IPR009822 YaeQ THITH_12410 7d766b8083f68c31835a472ec4ddcfac 181 Gene3D G3DSA:3.10.640.10 1 180 9.1E-70 T 13-10-2018 IPR038590 YaeQ superfamily THITH_12410 7d766b8083f68c31835a472ec4ddcfac 181 SMART SM01322 1 175 3.6E-108 T 13-10-2018 IPR009822 YaeQ THITH_12410 7d766b8083f68c31835a472ec4ddcfac 181 PIRSF PIRSF011484 1 180 3.9E-66 T 13-10-2018 IPR009822 YaeQ THITH_12410 7d766b8083f68c31835a472ec4ddcfac 181 SUPERFAMILY SSF52980 2 176 2.41E-65 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_10990 ef89874c5eb1612b65c61db15c6922b0 351 Pfam PF01595 Domain of unknown function DUF21 9 166 2.5E-38 T 13-10-2018 IPR002550 CNNM, transmembrane domain THITH_09075 61e8ea19b28ca0b31d627d638f1383cd 159 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 26 154 2.0E-28 T 13-10-2018 IPR005247 YbhB/YbcL THITH_09075 61e8ea19b28ca0b31d627d638f1383cd 159 Pfam PF01161 Phosphatidylethanolamine-binding protein 21 156 3.4E-36 T 13-10-2018 IPR008914 Phosphatidylethanolamine-binding protein THITH_09075 61e8ea19b28ca0b31d627d638f1383cd 159 SUPERFAMILY SSF49777 7 147 8.5E-44 T 13-10-2018 IPR036610 PEBP-like superfamily THITH_09075 61e8ea19b28ca0b31d627d638f1383cd 159 Gene3D G3DSA:3.90.280.10 3 159 3.1E-50 T 13-10-2018 IPR036610 PEBP-like superfamily THITH_14230 801134a249201f998393835ea70ce8ac 179 SUPERFAMILY SSF55282 3 178 3.53E-77 T 13-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14230 801134a249201f998393835ea70ce8ac 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 13-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14230 801134a249201f998393835ea70ce8ac 179 Pfam PF00281 Ribosomal protein L5 24 80 3.9E-27 T 13-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14230 801134a249201f998393835ea70ce8ac 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 1.7E-42 T 13-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14230 801134a249201f998393835ea70ce8ac 179 PIRSF PIRSF002161 1 179 2.5E-65 T 13-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14230 801134a249201f998393835ea70ce8ac 179 Gene3D G3DSA:3.30.1440.10 1 179 8.2E-80 T 13-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 THITH_14230 801134a249201f998393835ea70ce8ac 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 44.917 T 13-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_15275 c3827e79e21327c4ed473b371a566947 96 PRINTS PR00297 10kDa chaperonin signature 60 72 1.8E-33 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THITH_15275 c3827e79e21327c4ed473b371a566947 96 PRINTS PR00297 10kDa chaperonin signature 81 94 1.8E-33 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THITH_15275 c3827e79e21327c4ed473b371a566947 96 PRINTS PR00297 10kDa chaperonin signature 25 46 1.8E-33 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THITH_15275 c3827e79e21327c4ed473b371a566947 96 PRINTS PR00297 10kDa chaperonin signature 3 18 1.8E-33 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THITH_15275 c3827e79e21327c4ed473b371a566947 96 SMART SM00883 2 94 1.1E-58 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THITH_15275 c3827e79e21327c4ed473b371a566947 96 Pfam PF00166 Chaperonin 10 Kd subunit 2 94 1.2E-34 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THITH_15275 c3827e79e21327c4ed473b371a566947 96 Gene3D G3DSA:2.30.33.40 1 96 3.4E-37 T 13-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 THITH_15275 c3827e79e21327c4ed473b371a566947 96 Hamap MF_00580 10 kDa chaperonin [groS]. 2 95 27.461 T 13-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 THITH_15275 c3827e79e21327c4ed473b371a566947 96 ProSitePatterns PS00681 Chaperonins cpn10 signature. 3 27 - T 13-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 THITH_15275 c3827e79e21327c4ed473b371a566947 96 SUPERFAMILY SSF50129 1 95 1.22E-35 T 13-10-2018 IPR011032 GroES-like superfamily THITH_11910 f740af133b05f6308b3fe4bbc9642b46 456 Gene3D G3DSA:1.10.260.40 88 170 1.9E-17 T 13-10-2018 THITH_11910 f740af133b05f6308b3fe4bbc9642b46 456 Pfam PF13464 Domain of unknown function (DUF4115) 379 453 5.8E-16 T 13-10-2018 IPR025194 Domain of unknown function DUF4115 THITH_11910 f740af133b05f6308b3fe4bbc9642b46 456 Pfam PF13413 Helix-turn-helix domain 99 157 3.8E-17 T 13-10-2018 THITH_04230 83a9ac44871a6a257ac824c9e8dfac92 430 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 334 427 1.9E-8 T 13-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain THITH_04230 83a9ac44871a6a257ac824c9e8dfac92 430 Pfam PF01943 Polysaccharide biosynthesis protein 6 279 2.3E-12 T 13-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 THITH_08485 d10c1ea6ad1889cba4ca1fca53e7d3da 154 Pfam PF01814 Hemerythrin HHE cation binding domain 10 127 2.1E-10 T 13-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 THITH_08485 d10c1ea6ad1889cba4ca1fca53e7d3da 154 Gene3D G3DSA:1.20.120.520 2 142 6.7E-16 T 13-10-2018 THITH_12845 b6cc1d46c030fd240a17cf107886948e 591 Pfam PF00474 Sodium:solute symporter family 33 304 1.6E-36 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 THITH_12845 b6cc1d46c030fd240a17cf107886948e 591 Pfam PF00474 Sodium:solute symporter family 395 510 2.8E-14 T 13-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 THITH_12845 b6cc1d46c030fd240a17cf107886948e 591 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 8 585 1.3E-252 T 13-10-2018 IPR019899 Sodium/solute symporter, VC2705 subfamily THITH_12845 b6cc1d46c030fd240a17cf107886948e 591 Gene3D G3DSA:1.20.1730.10 21 330 1.8E-40 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily THITH_12845 b6cc1d46c030fd240a17cf107886948e 591 Gene3D G3DSA:1.20.1730.10 376 571 1.8E-22 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily THITH_06200 4b65a403415bf5789b5a4cf35b414765 475 Gene3D G3DSA:3.40.50.1820 5 256 8.0E-14 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_06200 4b65a403415bf5789b5a4cf35b414765 475 SUPERFAMILY SSF53474 7 182 8.01E-17 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_03360 44c52b11b8ad8fafde7288a4ea89ce2f 122 SUPERFAMILY SSF88723 1 116 6.17E-17 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_03360 44c52b11b8ad8fafde7288a4ea89ce2f 122 Pfam PF01850 PIN domain 2 113 5.4E-7 T 13-10-2018 IPR002716 PIN domain THITH_03360 44c52b11b8ad8fafde7288a4ea89ce2f 122 Gene3D G3DSA:3.40.50.1010 1 119 3.0E-10 T 13-10-2018 THITH_07135 de48dce265f2a74c1391f351c12751f1 210 SUPERFAMILY SSF46785 1 68 5.9E-18 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_07135 de48dce265f2a74c1391f351c12751f1 210 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 123 134 1.2E-12 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 THITH_07135 de48dce265f2a74c1391f351c12751f1 210 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 112 122 1.2E-12 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 THITH_07135 de48dce265f2a74c1391f351c12751f1 210 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 151 163 1.2E-12 T 13-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 THITH_07135 de48dce265f2a74c1391f351c12751f1 210 Gene3D G3DSA:2.10.109.10 81 201 6.8E-44 T 13-10-2018 THITH_07135 de48dce265f2a74c1391f351c12751f1 210 Pfam PF00717 Peptidase S24-like 115 182 1.4E-16 T 13-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C THITH_07135 de48dce265f2a74c1391f351c12751f1 210 Pfam PF01726 LexA DNA binding domain 2 64 3.1E-23 T 13-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 THITH_07135 de48dce265f2a74c1391f351c12751f1 210 Hamap MF_00015 LexA repressor [lexA]. 2 200 32.647 T 13-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 THITH_07135 de48dce265f2a74c1391f351c12751f1 210 Gene3D G3DSA:1.10.10.10 1 68 3.0E-25 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_07135 de48dce265f2a74c1391f351c12751f1 210 SUPERFAMILY SSF51306 76 198 2.44E-38 T 13-10-2018 IPR036286 LexA/Signal peptidase-like superfamily THITH_07135 de48dce265f2a74c1391f351c12751f1 210 TIGRFAM TIGR00498 lexA: repressor LexA 2 200 7.8E-69 T 13-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 THITH_16680 37e925df05d949f25607c56082e5ec37 184 Gene3D G3DSA:3.40.630.30 11 161 3.1E-40 T 13-10-2018 THITH_16680 37e925df05d949f25607c56082e5ec37 184 SUPERFAMILY SSF55729 8 148 5.32E-22 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_16680 37e925df05d949f25607c56082e5ec37 184 Pfam PF00583 Acetyltransferase (GNAT) family 53 148 1.7E-9 T 13-10-2018 IPR000182 GNAT domain THITH_03285 695cbf20a32b2d243074e1a55894efd7 240 Pfam PF01618 MotA/TolQ/ExbB proton channel family 82 204 1.3E-31 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel THITH_15575 9f2f46fca1aa3d4392d6b4a94410fda9 439 Pfam PF01029 NusB family 11 130 4.9E-17 T 13-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 THITH_15575 9f2f46fca1aa3d4392d6b4a94410fda9 439 Gene3D G3DSA:3.40.50.150 235 438 5.3E-59 T 13-10-2018 THITH_15575 9f2f46fca1aa3d4392d6b4a94410fda9 439 Pfam PF01189 16S rRNA methyltransferase RsmB/F 245 435 5.4E-55 T 13-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 THITH_15575 9f2f46fca1aa3d4392d6b4a94410fda9 439 Gene3D G3DSA:1.10.940.10 6 148 2.0E-30 T 13-10-2018 IPR035926 NusB-like superfamily THITH_15575 9f2f46fca1aa3d4392d6b4a94410fda9 439 Gene3D G3DSA:3.30.70.1170 177 234 1.5E-17 T 13-10-2018 THITH_15575 9f2f46fca1aa3d4392d6b4a94410fda9 439 SUPERFAMILY SSF48013 11 153 1.28E-27 T 13-10-2018 IPR035926 NusB-like superfamily THITH_15575 9f2f46fca1aa3d4392d6b4a94410fda9 439 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 18 436 9.0E-102 T 13-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 THITH_15575 9f2f46fca1aa3d4392d6b4a94410fda9 439 SUPERFAMILY SSF53335 142 437 3.07E-65 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_15575 9f2f46fca1aa3d4392d6b4a94410fda9 439 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 322 334 2.1E-26 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase THITH_15575 9f2f46fca1aa3d4392d6b4a94410fda9 439 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 226 240 2.1E-26 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase THITH_15575 9f2f46fca1aa3d4392d6b4a94410fda9 439 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 255 265 2.1E-26 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase THITH_15575 9f2f46fca1aa3d4392d6b4a94410fda9 439 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 420 437 2.1E-26 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase THITH_15575 9f2f46fca1aa3d4392d6b4a94410fda9 439 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 372 388 2.1E-26 T 13-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase THITH_15575 9f2f46fca1aa3d4392d6b4a94410fda9 439 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 321 332 - T 13-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 THITH_16285 11ae3a4e2b9946c366aec123e63b0f3b 266 Pfam PF01738 Dienelactone hydrolase family 43 263 5.0E-40 T 13-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 THITH_16285 11ae3a4e2b9946c366aec123e63b0f3b 266 Gene3D G3DSA:3.40.50.1820 17 266 5.3E-55 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_16285 11ae3a4e2b9946c366aec123e63b0f3b 266 SUPERFAMILY SSF53474 28 265 4.9E-39 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_00145 f4e1de58cfc415dc63f19f30cafb1ba3 283 Gene3D G3DSA:2.30.30.830 89 155 3.7E-20 T 13-10-2018 THITH_00145 f4e1de58cfc415dc63f19f30cafb1ba3 283 Pfam PF11356 Type II secretion system protein C 18 155 2.7E-35 T 13-10-2018 IPR024961 Type II secretion system protein C, N-terminal THITH_00145 f4e1de58cfc415dc63f19f30cafb1ba3 283 TIGRFAM TIGR01713 typeII_sec_gspC: type II secretion system protein C 14 275 2.9E-37 T 13-10-2018 IPR001639 Type II secretion system protein C GO:0008565|GO:0015627|GO:0015628 THITH_00145 f4e1de58cfc415dc63f19f30cafb1ba3 283 Gene3D G3DSA:2.30.42.10 180 280 9.7E-24 T 13-10-2018 THITH_00145 f4e1de58cfc415dc63f19f30cafb1ba3 283 Pfam PF13180 PDZ domain 213 280 1.2E-8 T 13-10-2018 IPR001478 PDZ domain GO:0005515 THITH_00145 f4e1de58cfc415dc63f19f30cafb1ba3 283 SUPERFAMILY SSF50156 188 280 1.01E-15 T 13-10-2018 IPR036034 PDZ superfamily GO:0005515 THITH_06320 43b88848f12b2235067c26fcf5bd1f09 280 Pfam PF05036 Sporulation related domain 207 270 1.5E-8 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 THITH_06320 43b88848f12b2235067c26fcf5bd1f09 280 SUPERFAMILY SSF50685 71 172 9.77E-11 T 13-10-2018 IPR036908 RlpA-like domain superfamily THITH_06320 43b88848f12b2235067c26fcf5bd1f09 280 Gene3D G3DSA:3.30.70.1070 199 278 1.5E-8 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 THITH_06320 43b88848f12b2235067c26fcf5bd1f09 280 TIGRFAM TIGR00413 rlpA: rare lipoprotein A 83 174 1.4E-43 T 13-10-2018 IPR012997 Rare lipoprotein A THITH_06320 43b88848f12b2235067c26fcf5bd1f09 280 Gene3D G3DSA:2.40.40.10 80 173 1.6E-36 T 13-10-2018 IPR036908 RlpA-like domain superfamily THITH_06320 43b88848f12b2235067c26fcf5bd1f09 280 Pfam PF03330 Lytic transglycolase 81 169 4.5E-25 T 13-10-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain THITH_06320 43b88848f12b2235067c26fcf5bd1f09 280 Hamap MF_02071 Endolytic peptidoglycan transglycosylase RlpA [rlpA]. 10 173 24.962 T 13-10-2018 IPR034718 Endolytic peptidoglycan transglycosylase RlpA GO:0016829 THITH_06320 43b88848f12b2235067c26fcf5bd1f09 280 SUPERFAMILY SSF110997 204 278 5.75E-11 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 THITH_11475 2526be473f35b24d55fe0399ac266d5b 364 Pfam PF06114 IrrE N-terminal-like domain 246 306 2.5E-5 T 13-10-2018 IPR010359 IrrE N-terminal-like domain THITH_11475 2526be473f35b24d55fe0399ac266d5b 364 SMART SM00530 19 74 1.8E-8 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_11475 2526be473f35b24d55fe0399ac266d5b 364 SUPERFAMILY SSF47413 15 89 2.55E-20 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 THITH_11475 2526be473f35b24d55fe0399ac266d5b 364 Gene3D G3DSA:1.10.260.40 13 104 1.6E-23 T 13-10-2018 THITH_11475 2526be473f35b24d55fe0399ac266d5b 364 Pfam PF01381 Helix-turn-helix 20 69 1.8E-8 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_02755 4e4d59278d53f1f800e3a6e6f858b6aa 1306 Pfam PF13116 Protein of unknown function 530 808 2.0E-51 T 13-10-2018 IPR025263 Domain of unknown function DUF3971 THITH_02755 4e4d59278d53f1f800e3a6e6f858b6aa 1306 TIGRFAM TIGR02099 TIGR02099: TIGR02099 family protein 41 1303 3.1E-175 T 13-10-2018 IPR011836 Conserved hypothetical protein CHP02099 THITH_02755 4e4d59278d53f1f800e3a6e6f858b6aa 1306 Pfam PF13502 AsmA-like C-terminal region 1051 1295 4.5E-45 T 13-10-2018 IPR032712 AsmA-like, C-terminal THITH_01005 24f6326d54b604649d7f844fe987dda8 323 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 317 9.3E-33 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THITH_01005 24f6326d54b604649d7f844fe987dda8 323 SUPERFAMILY SSF161098 88 306 1.19E-13 T 13-10-2018 IPR035906 MetI-like superfamily THITH_01005 24f6326d54b604649d7f844fe987dda8 323 Gene3D G3DSA:1.10.3720.10 84 313 5.4E-15 T 13-10-2018 IPR035906 MetI-like superfamily THITH_13255 922056eb8e5acc9a6f4bbe1867efbfce 224 Pfam PF01618 MotA/TolQ/ExbB proton channel family 84 191 3.9E-34 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel THITH_07260 a3fb8caa46a5df81ef25d4350b3f7a9a 120 Gene3D G3DSA:3.40.30.10 6 116 1.2E-37 T 13-10-2018 THITH_07260 a3fb8caa46a5df81ef25d4350b3f7a9a 120 Pfam PF03960 ArsC family 9 112 1.7E-12 T 13-10-2018 IPR006660 Arsenate reductase-like THITH_07260 a3fb8caa46a5df81ef25d4350b3f7a9a 120 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 8 111 1.2E-22 T 13-10-2018 IPR006504 Transcriptional regulator Spx/MgsR THITH_07260 a3fb8caa46a5df81ef25d4350b3f7a9a 120 SUPERFAMILY SSF52833 7 113 1.72E-29 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_10090 7fae8bc45e688d3a66ace671c3d7e0d4 370 Pfam PF13692 Glycosyl transferases group 1 180 325 3.2E-17 T 13-10-2018 THITH_10090 7fae8bc45e688d3a66ace671c3d7e0d4 370 SUPERFAMILY SSF53756 3 357 1.54E-45 T 13-10-2018 THITH_10090 7fae8bc45e688d3a66ace671c3d7e0d4 370 Gene3D G3DSA:3.40.50.2000 177 345 5.9E-29 T 13-10-2018 THITH_10090 7fae8bc45e688d3a66ace671c3d7e0d4 370 Pfam PF13439 Glycosyltransferase Family 4 48 165 2.7E-13 T 13-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 THITH_10090 7fae8bc45e688d3a66ace671c3d7e0d4 370 Gene3D G3DSA:3.40.50.2000 7 175 2.4E-15 T 13-10-2018 THITH_10660 9aeb5bce09a7dbe4564a2cdfe2ddabc2 162 TIGRFAM TIGR01848 PHA_reg_PhaR: polyhydroxyalkanoate synthesis repressor PhaR 5 110 3.2E-42 T 13-10-2018 IPR010134 Polyhydroxyalkanoate synthesis repressor PhaR GO:0006355 THITH_10660 9aeb5bce09a7dbe4564a2cdfe2ddabc2 162 Pfam PF07879 PHB/PHA accumulation regulator DNA-binding domain 6 65 1.4E-29 T 13-10-2018 IPR012909 PHA accumulation regulator DNA-binding, N-terminal THITH_10660 9aeb5bce09a7dbe4564a2cdfe2ddabc2 162 Pfam PF05233 PHB accumulation regulatory domain 70 109 4.7E-15 T 13-10-2018 IPR007897 PHB accumulation regulatory THITH_06485 f0ae4d83c7f2bb47301e2b650b786425 157 SUPERFAMILY SSF53163 16 133 7.06E-20 T 13-10-2018 IPR023430 Peptidase HybD-like domain superfamily THITH_06485 f0ae4d83c7f2bb47301e2b650b786425 157 Gene3D G3DSA:3.40.50.1450 16 156 1.4E-25 T 13-10-2018 IPR023430 Peptidase HybD-like domain superfamily THITH_06485 f0ae4d83c7f2bb47301e2b650b786425 157 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 19 132 4.8E-21 T 13-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THITH_06485 f0ae4d83c7f2bb47301e2b650b786425 157 Pfam PF01750 Hydrogenase maturation protease 57 130 4.2E-12 T 13-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 THITH_03390 cba345019b604fdeb1f6eff769758b22 101 Gene3D G3DSA:3.30.460.10 1 97 3.1E-8 T 13-10-2018 THITH_03390 cba345019b604fdeb1f6eff769758b22 101 Pfam PF01909 Nucleotidyltransferase domain 19 82 1.5E-5 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THITH_03390 cba345019b604fdeb1f6eff769758b22 101 SUPERFAMILY SSF81301 9 51 3.82E-6 T 13-10-2018 THITH_00410 7c8ef93f0e5c4381b54c7364ea738b5e 162 SMART SM00738 1 100 6.2E-19 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THITH_00410 7c8ef93f0e5c4381b54c7364ea738b5e 162 Pfam PF02357 Transcription termination factor nusG 2 95 2.0E-20 T 13-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THITH_00410 7c8ef93f0e5c4381b54c7364ea738b5e 162 Gene3D G3DSA:3.30.70.940 1 161 6.3E-51 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THITH_00410 7c8ef93f0e5c4381b54c7364ea738b5e 162 SUPERFAMILY SSF82679 2 103 4.32E-28 T 13-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 THITH_02405 cfe0c831a82c6da6549c020ed186538a 184 Gene3D G3DSA:2.40.70.10 30 158 4.0E-35 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily THITH_02405 cfe0c831a82c6da6549c020ed186538a 184 Pfam PF05618 Putative ATP-dependant zinc protease 33 166 2.3E-33 T 13-10-2018 THITH_02405 cfe0c831a82c6da6549c020ed186538a 184 SUPERFAMILY SSF50630 33 165 3.21E-35 T 13-10-2018 IPR021109 Aspartic peptidase domain superfamily THITH_05565 154498b3475c3bb52db6224954cece78 265 PIRSF PIRSF016557 1 251 3.8E-68 T 13-10-2018 IPR016667 Capsular polysaccharide synthesis, CpsB/CapC GO:0004725|GO:0030145 THITH_05565 154498b3475c3bb52db6224954cece78 265 Gene3D G3DSA:3.20.20.140 1 252 1.9E-77 T 13-10-2018 THITH_05565 154498b3475c3bb52db6224954cece78 265 SUPERFAMILY SSF89550 1 203 2.12E-12 T 13-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 THITH_00685 171ae2ca92b7213d5b653cd4b1682431 332 SUPERFAMILY SSF51430 2 320 1.02E-34 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily THITH_00685 171ae2ca92b7213d5b653cd4b1682431 332 Pfam PF00248 Aldo/keto reductase family 6 184 1.8E-27 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain THITH_00685 171ae2ca92b7213d5b653cd4b1682431 332 Gene3D G3DSA:3.20.20.100 1 328 8.9E-30 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily THITH_00435 ae6639dbb08cd718ccca85a5a37017ef 245 Pfam PF09955 Predicted integral membrane protein (DUF2189) 47 166 1.9E-5 T 13-10-2018 IPR018692 Predicted integral membrane protein DUF2189 THITH_02070 5d3655654527154191ee654a10376f97 337 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 12 337 1.7E-110 T 13-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_02070 5d3655654527154191ee654a10376f97 337 SUPERFAMILY SSF102114 12 283 3.79E-69 T 13-10-2018 THITH_02070 5d3655654527154191ee654a10376f97 337 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 12 337 39.004 T 13-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_02070 5d3655654527154191ee654a10376f97 337 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 27 38 - T 13-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_02070 5d3655654527154191ee654a10376f97 337 Pfam PF06463 Molybdenum Cofactor Synthesis C 191 318 1.9E-35 T 13-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 THITH_02070 5d3655654527154191ee654a10376f97 337 SMART SM00729 21 224 1.4E-11 T 13-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 THITH_02070 5d3655654527154191ee654a10376f97 337 Gene3D G3DSA:3.20.20.70 9 337 9.5E-83 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_02070 5d3655654527154191ee654a10376f97 337 Pfam PF04055 Radical SAM superfamily 26 186 1.6E-25 T 13-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 THITH_02070 5d3655654527154191ee654a10376f97 337 Pfam PF13353 4Fe-4S single cluster domain 28 129 3.4E-7 T 13-10-2018 THITH_02200 b92e3657eaafbdd68b50a6e35dc19708 86 Pfam PF14076 Domain of unknown function (DUF4258) 12 78 3.5E-12 T 13-10-2018 IPR025354 Protein of unknown function DUF4258 THITH_14915 3f63cbcf4af904f2634365bb0713a59a 152 Gene3D G3DSA:1.10.10.410 91 147 1.2E-16 T 13-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal THITH_14915 3f63cbcf4af904f2634365bb0713a59a 152 Gene3D G3DSA:1.10.1510.10 1 90 2.3E-26 T 13-10-2018 THITH_14915 3f63cbcf4af904f2634365bb0713a59a 152 Pfam PF09424 Yqey-like protein 4 146 5.0E-49 T 13-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 THITH_14915 3f63cbcf4af904f2634365bb0713a59a 152 SUPERFAMILY SSF89095 1 146 1.78E-37 T 13-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 THITH_08130 cc21f524dbca0b539eed6028989c3ab5 135 SUPERFAMILY SSF46626 41 132 4.0E-7 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_08130 cc21f524dbca0b539eed6028989c3ab5 135 Pfam PF07635 Planctomycete cytochrome C 51 110 5.1E-7 T 13-10-2018 IPR011429 Cytochrome C, Planctomycete-type THITH_17035 a446679c5cc139917f147f3c8b3efb51 100 Pfam PF11373 Protein of unknown function (DUF3175) 8 93 1.3E-44 T 13-10-2018 IPR021513 Ralstonia phage RSL1, Orf186 THITH_15995 59ba455f3af5a7683db2b107191f5780 181 Gene3D G3DSA:1.10.1760.20 12 165 2.9E-8 T 13-10-2018 THITH_15995 59ba455f3af5a7683db2b107191f5780 181 PIRSF PIRSF027391 9 176 5.4E-31 T 13-10-2018 IPR014535 Predicted heptaprenyl diphosphate synthase, component I THITH_15995 59ba455f3af5a7683db2b107191f5780 181 Pfam PF07456 Heptaprenyl diphosphate synthase component I 16 159 7.9E-38 T 13-10-2018 IPR010898 Heptaprenyl diphosphate synthase component I THITH_15395 a3244b6b48e391425f1808ea64f72c2e 90 SUPERFAMILY SSF55008 2 61 3.14E-11 T 13-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 THITH_15395 a3244b6b48e391425f1808ea64f72c2e 90 Gene3D G3DSA:3.30.70.100 1 67 6.4E-13 T 13-10-2018 THITH_15395 a3244b6b48e391425f1808ea64f72c2e 90 Pfam PF00403 Heavy-metal-associated domain 3 60 3.0E-11 T 13-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 THITH_16055 8260cf273a74ca40fbf2c28e2640c8fc 185 Pfam PF02325 YGGT family 110 181 3.8E-15 T 13-10-2018 IPR003425 CCB3/YggT GO:0016020 THITH_16055 8260cf273a74ca40fbf2c28e2640c8fc 185 Pfam PF02325 YGGT family 15 82 1.2E-14 T 13-10-2018 IPR003425 CCB3/YggT GO:0016020 THITH_00715 0e7ca4a8c8ede9aa96d9e4f6c689d2c7 301 SUPERFAMILY SSF46626 35 161 1.01E-22 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_00715 0e7ca4a8c8ede9aa96d9e4f6c689d2c7 301 SUPERFAMILY SSF46626 174 291 8.09E-14 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_00715 0e7ca4a8c8ede9aa96d9e4f6c689d2c7 301 PIRSF PIRSF000018 4 299 6.2E-94 T 13-10-2018 IPR014353 Membrane-bound alcohol dehydrogenase, cytochrome c subunit GO:0005506|GO:0016020|GO:0016614|GO:0020037 THITH_00715 0e7ca4a8c8ede9aa96d9e4f6c689d2c7 301 Gene3D G3DSA:1.10.760.10 4 149 4.1E-11 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_00715 0e7ca4a8c8ede9aa96d9e4f6c689d2c7 301 Gene3D G3DSA:1.10.760.10 159 298 7.9E-7 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_00715 0e7ca4a8c8ede9aa96d9e4f6c689d2c7 301 Pfam PF00034 Cytochrome c 38 138 2.6E-5 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_02140 15ab59dc8ae3f6da4f5c290a179d73c1 291 Hamap MF_00187 Sulfur carrier protein FdhD [fdhD]. 17 273 26.939 T 13-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 THITH_02140 15ab59dc8ae3f6da4f5c290a179d73c1 291 Gene3D G3DSA:3.10.20.10 42 124 3.0E-9 T 13-10-2018 THITH_02140 15ab59dc8ae3f6da4f5c290a179d73c1 291 Gene3D G3DSA:3.40.140.10 131 277 1.1E-40 T 13-10-2018 THITH_02140 15ab59dc8ae3f6da4f5c290a179d73c1 291 SUPERFAMILY SSF53927 25 273 2.86E-71 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 THITH_02140 15ab59dc8ae3f6da4f5c290a179d73c1 291 Pfam PF02634 FdhD/NarQ family 41 272 1.1E-72 T 13-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 THITH_02140 15ab59dc8ae3f6da4f5c290a179d73c1 291 PIRSF PIRSF015626 2 276 5.5E-79 T 13-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 THITH_04800 cb7aee656a1e18b93d4e13b53ecb068a 181 SMART SM00463 92 176 5.0E-15 T 13-10-2018 IPR002625 Smr domain THITH_04800 cb7aee656a1e18b93d4e13b53ecb068a 181 SUPERFAMILY SSF160443 93 176 4.58E-17 T 13-10-2018 IPR036063 Smr domain superfamily THITH_04800 cb7aee656a1e18b93d4e13b53ecb068a 181 Pfam PF01713 Smr domain 95 176 4.4E-21 T 13-10-2018 IPR002625 Smr domain THITH_04800 cb7aee656a1e18b93d4e13b53ecb068a 181 Gene3D G3DSA:3.30.1370.110 46 180 1.4E-43 T 13-10-2018 THITH_06790 5da5ff0d443f742d71272054ea1ccdf4 365 Gene3D G3DSA:1.10.645.10 194 358 1.3E-20 T 13-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_06790 5da5ff0d443f742d71272054ea1ccdf4 365 Pfam PF00374 Nickel-dependent hydrogenase 269 325 1.2E-9 T 13-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 THITH_06790 5da5ff0d443f742d71272054ea1ccdf4 365 SUPERFAMILY SSF56762 6 356 4.71E-36 T 13-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_08205 cf7444d7bae7f526eb4d095acb45d716 237 Gene3D G3DSA:1.10.3480.10 2 181 2.0E-10 T 13-10-2018 THITH_08205 cf7444d7bae7f526eb4d095acb45d716 237 SUPERFAMILY SSF89155 2 164 9.81E-32 T 13-10-2018 IPR036411 TorD-like superfamily THITH_08205 cf7444d7bae7f526eb4d095acb45d716 237 Pfam PF02613 Nitrate reductase delta subunit 35 130 2.4E-12 T 13-10-2018 IPR020945 DMSO/Nitrate reductase chaperone THITH_08205 cf7444d7bae7f526eb4d095acb45d716 237 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 8 161 8.6E-36 T 13-10-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 THITH_06340 50e8a53342fc30d7ddddcf9575b9f40f 226 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 31 201 8.6E-54 T 13-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 THITH_06340 50e8a53342fc30d7ddddcf9575b9f40f 226 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 71 86 - T 13-10-2018 IPR020605 Octanoyltransferase, conserved site GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 THITH_06340 50e8a53342fc30d7ddddcf9575b9f40f 226 Gene3D G3DSA:3.30.930.10 2 204 1.2E-58 T 13-10-2018 THITH_06340 50e8a53342fc30d7ddddcf9575b9f40f 226 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 75 128 6.0E-6 T 13-10-2018 THITH_06340 50e8a53342fc30d7ddddcf9575b9f40f 226 Hamap MF_00013 Octanoyltransferase [lipB]. 5 206 34.421 T 13-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 THITH_06340 50e8a53342fc30d7ddddcf9575b9f40f 226 Pfam PF03099 Biotin/lipoate A/B protein ligase family 59 156 2.4E-5 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 THITH_06340 50e8a53342fc30d7ddddcf9575b9f40f 226 PIRSF PIRSF016262 2 212 5.0E-52 T 13-10-2018 IPR000544 Octanoyltransferase GO:0009249|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 THITH_06340 50e8a53342fc30d7ddddcf9575b9f40f 226 SUPERFAMILY SSF55681 8 206 2.4E-61 T 13-10-2018 THITH_02080 32a0b690b42d5fed366248d5eec260d8 195 Pfam PF12804 MobA-like NTP transferase domain 1 153 3.4E-35 T 13-10-2018 IPR025877 MobA-like NTP transferase THITH_02080 32a0b690b42d5fed366248d5eec260d8 195 TIGRFAM TIGR02665 molyb_mobA: molybdenum cofactor guanylyltransferase 1 181 8.7E-72 T 13-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 THITH_02080 32a0b690b42d5fed366248d5eec260d8 195 Gene3D G3DSA:3.90.550.10 1 187 3.5E-57 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_02080 32a0b690b42d5fed366248d5eec260d8 195 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 183 27.129 T 13-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 THITH_02080 32a0b690b42d5fed366248d5eec260d8 195 SUPERFAMILY SSF53448 1 180 6.26E-38 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_09735 f1f8d6cbecfd7a13cde4acc4dd298e59 89 Gene3D G3DSA:3.30.460.10 4 87 1.8E-16 T 13-10-2018 THITH_09735 f1f8d6cbecfd7a13cde4acc4dd298e59 89 SUPERFAMILY SSF81301 6 82 7.01E-13 T 13-10-2018 THITH_04445 a76a0bbb3b46ebd27eff96c8f26180d9 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 162 186 2.4E-13 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04445 a76a0bbb3b46ebd27eff96c8f26180d9 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 234 258 2.4E-13 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04445 a76a0bbb3b46ebd27eff96c8f26180d9 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 322 341 2.4E-13 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04445 a76a0bbb3b46ebd27eff96c8f26180d9 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 374 400 2.4E-13 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04445 a76a0bbb3b46ebd27eff96c8f26180d9 510 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 132 151 2.4E-13 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04445 a76a0bbb3b46ebd27eff96c8f26180d9 510 Pfam PF00361 Proton-conducting membrane transporter 128 417 4.0E-56 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_03185 6b9799d2a4cc20803a35982b73118864 2520 Pfam PF00801 PKD domain 1813 1879 4.0E-7 T 13-10-2018 IPR000601 PKD domain THITH_03185 6b9799d2a4cc20803a35982b73118864 2520 SUPERFAMILY SSF89260 2277 2384 2.35E-9 T 13-10-2018 THITH_03185 6b9799d2a4cc20803a35982b73118864 2520 SUPERFAMILY SSF49299 1815 1889 3.27E-5 T 13-10-2018 IPR035986 PKD domain superfamily THITH_03185 6b9799d2a4cc20803a35982b73118864 2520 SUPERFAMILY SSF89260 2156 2263 5.23E-10 T 13-10-2018 THITH_03185 6b9799d2a4cc20803a35982b73118864 2520 SUPERFAMILY SSF89260 2398 2508 5.89E-8 T 13-10-2018 THITH_03185 6b9799d2a4cc20803a35982b73118864 2520 Gene3D G3DSA:2.60.40.10 1808 1890 6.6E-5 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_03185 6b9799d2a4cc20803a35982b73118864 2520 Gene3D G3DSA:2.60.120.380 2394 2508 8.1E-16 T 13-10-2018 THITH_03185 6b9799d2a4cc20803a35982b73118864 2520 Gene3D G3DSA:2.60.120.380 1923 2021 5.0E-9 T 13-10-2018 THITH_03185 6b9799d2a4cc20803a35982b73118864 2520 Gene3D G3DSA:2.60.120.380 2027 2145 2.8E-14 T 13-10-2018 THITH_03185 6b9799d2a4cc20803a35982b73118864 2520 Gene3D G3DSA:2.60.120.380 2152 2266 2.8E-18 T 13-10-2018 THITH_03185 6b9799d2a4cc20803a35982b73118864 2520 Gene3D G3DSA:2.60.120.380 2273 2387 1.4E-17 T 13-10-2018 THITH_03185 6b9799d2a4cc20803a35982b73118864 2520 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 2311 2376 1.9E-5 T 13-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial THITH_03185 6b9799d2a4cc20803a35982b73118864 2520 SUPERFAMILY SSF89260 2031 2142 2.09E-10 T 13-10-2018 THITH_15180 80b6b6b9018d4fd387fa780e913b0b10 72 Gene3D G3DSA:2.60.260.40 15 71 7.2E-11 T 13-10-2018 THITH_15180 80b6b6b9018d4fd387fa780e913b0b10 72 Pfam PF10276 Zinc-finger domain 33 68 5.3E-8 T 13-10-2018 IPR019401 Zinc finger, CHCC-type Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_11610 439e803fbf43457f22388803fe64c72d 317 PRINTS PR00184 Neisseria sp. porin signature 143 160 1.4E-8 T 13-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 THITH_11610 439e803fbf43457f22388803fe64c72d 317 PRINTS PR00184 Neisseria sp. porin signature 269 293 1.4E-8 T 13-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 THITH_11610 439e803fbf43457f22388803fe64c72d 317 PRINTS PR00184 Neisseria sp. porin signature 49 74 1.4E-8 T 13-10-2018 IPR002299 Porin, Neisseria sp. type GO:0015288|GO:0016020|GO:0055085 THITH_11610 439e803fbf43457f22388803fe64c72d 317 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 272 289 4.9E-9 T 13-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 THITH_11610 439e803fbf43457f22388803fe64c72d 317 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 144 155 4.9E-9 T 13-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 THITH_11610 439e803fbf43457f22388803fe64c72d 317 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 91 101 4.9E-9 T 13-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 THITH_11610 439e803fbf43457f22388803fe64c72d 317 PRINTS PR00182 E.coli/Neisseria porin superfamily signature 47 58 4.9E-9 T 13-10-2018 IPR001702 Porin, Gram-negative type GO:0015288|GO:0016020|GO:0055085 THITH_11610 439e803fbf43457f22388803fe64c72d 317 Pfam PF13609 Gram-negative porin 7 294 5.7E-41 T 13-10-2018 THITH_11610 439e803fbf43457f22388803fe64c72d 317 SUPERFAMILY SSF56935 25 317 9.42E-49 T 13-10-2018 THITH_11610 439e803fbf43457f22388803fe64c72d 317 Gene3D G3DSA:2.40.160.10 22 317 1.6E-54 T 13-10-2018 IPR023614 Porin domain superfamily THITH_02790 7eb89341bf45c72345448847f2c7d438 191 PIRSF PIRSF000847 1 176 4.7E-38 T 13-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 THITH_02790 7eb89341bf45c72345448847f2c7d438 191 Gene3D G3DSA:1.20.120.1760 1 172 2.3E-11 T 13-10-2018 THITH_02790 7eb89341bf45c72345448847f2c7d438 191 Pfam PF01066 CDP-alcohol phosphatidyltransferase 6 69 1.2E-13 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THITH_13135 771f1a8adc211721840a7a7b06de70c3 351 SUPERFAMILY SSF46785 6 85 1.27E-22 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_13135 771f1a8adc211721840a7a7b06de70c3 351 Gene3D G3DSA:3.30.390.60 131 232 4.5E-39 T 13-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily THITH_13135 771f1a8adc211721840a7a7b06de70c3 351 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 8 340 7.3E-98 T 13-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 THITH_13135 771f1a8adc211721840a7a7b06de70c3 351 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 5 334 27.936 T 13-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 THITH_13135 771f1a8adc211721840a7a7b06de70c3 351 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 7 77 2.1E-7 T 13-10-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 THITH_13135 771f1a8adc211721840a7a7b06de70c3 351 Gene3D G3DSA:1.10.10.10 1 88 1.4E-31 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_13135 771f1a8adc211721840a7a7b06de70c3 351 PIRSF PIRSF005485 3 345 7.5E-107 T 13-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 THITH_13135 771f1a8adc211721840a7a7b06de70c3 351 Gene3D G3DSA:3.30.450.40 109 337 4.5E-39 T 13-10-2018 IPR029016 GAF-like domain superfamily THITH_13135 771f1a8adc211721840a7a7b06de70c3 351 Pfam PF01628 HrcA protein C terminal domain 107 327 1.6E-56 T 13-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 THITH_13135 771f1a8adc211721840a7a7b06de70c3 351 SUPERFAMILY SSF55781 75 343 2.9E-60 T 13-10-2018 THITH_08550 d4b33b55e39fe7a582b4f7d69eededc1 209 Pfam PF06736 Protein of unknown function (DUF1211) 23 111 1.5E-21 T 13-10-2018 IPR010617 Endosomal/lysomomal potassium channel TMEM175 GO:0005267 THITH_02840 0cdb4537f54708e62669d51cd39f03e9 294 Gene3D G3DSA:3.40.50.1820 25 255 8.5E-33 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_02840 0cdb4537f54708e62669d51cd39f03e9 294 SUPERFAMILY SSF53474 6 269 4.02E-37 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_02840 0cdb4537f54708e62669d51cd39f03e9 294 Pfam PF12146 Serine aminopeptidase, S33 71 181 5.0E-9 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 THITH_09335 6a71b7a89d120483b99915dbdb8afe4f 547 Pfam PF03787 RAMP superfamily 12 201 5.6E-7 T 13-10-2018 IPR005537 CRISPR type III-associated RAMP protein THITH_04810 f10b4e22428a23ec2d608370e621b7e7 221 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 13 220 2.3E-61 T 13-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 THITH_04810 f10b4e22428a23ec2d608370e621b7e7 221 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 16 218 3.8E-56 T 13-10-2018 THITH_04810 f10b4e22428a23ec2d608370e621b7e7 221 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 11 221 35.547 T 13-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 THITH_04810 f10b4e22428a23ec2d608370e621b7e7 221 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 141 156 - T 13-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 THITH_04810 f10b4e22428a23ec2d608370e621b7e7 221 Gene3D G3DSA:3.40.50.150 5 220 3.2E-70 T 13-10-2018 THITH_04810 f10b4e22428a23ec2d608370e621b7e7 221 SUPERFAMILY SSF53335 22 219 9.43E-43 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_15550 877de3bc59309dbf869ed0231672e144 113 SUPERFAMILY SSF48452 6 84 1.84E-15 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_15550 877de3bc59309dbf869ed0231672e144 113 SMART SM00028 19 52 3.0E-4 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_15550 877de3bc59309dbf869ed0231672e144 113 SMART SM00028 53 86 10.0 T 13-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 THITH_15550 877de3bc59309dbf869ed0231672e144 113 Gene3D G3DSA:1.25.40.10 1 110 7.1E-24 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_15550 877de3bc59309dbf869ed0231672e144 113 Pfam PF14559 Tetratricopeptide repeat 29 85 5.7E-11 T 13-10-2018 THITH_02550 f011927adbe31211c8028926d6ad8a88 379 Hamap MF_01270 Anhydro-N-acetylmuramic acid kinase [anmK]. 3 370 37.919 T 13-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 THITH_02550 f011927adbe31211c8028926d6ad8a88 379 Gene3D G3DSA:3.30.420.40 145 330 5.7E-120 T 13-10-2018 THITH_02550 f011927adbe31211c8028926d6ad8a88 379 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 3 369 2.6E-130 T 13-10-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 MetaCyc: PWY-7883 THITH_02550 f011927adbe31211c8028926d6ad8a88 379 Gene3D G3DSA:3.30.420.40 10 365 5.7E-120 T 13-10-2018 THITH_02550 f011927adbe31211c8028926d6ad8a88 379 SUPERFAMILY SSF53067 66 342 8.2E-23 T 13-10-2018 THITH_08025 3b559c4deeb038d74c8f166ee64cf184 132 Gene3D G3DSA:3.30.479.10 1 131 1.1E-26 T 13-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 THITH_08025 3b559c4deeb038d74c8f166ee64cf184 132 SUPERFAMILY SSF55620 1 129 1.89E-27 T 13-10-2018 THITH_08025 3b559c4deeb038d74c8f166ee64cf184 132 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 4 129 8.1E-22 T 13-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 THITH_05825 25dc4c48861f4bdbd04b1c8433eb7df8 257 Pfam PF02698 DUF218 domain 83 246 2.9E-22 T 13-10-2018 IPR003848 Domain of unknown function DUF218 THITH_11760 66b5685d2991ae829859693dfa0f1fe7 188 Pfam PF02687 FtsX-like permease family 86 178 2.4E-9 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THITH_07530 f7946b6aa3d0e5872fe7673ed71736b4 278 Pfam PF12697 Alpha/beta hydrolase family 13 260 1.1E-17 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_07530 f7946b6aa3d0e5872fe7673ed71736b4 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 38 53 9.2E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_07530 f7946b6aa3d0e5872fe7673ed71736b4 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 94 9.2E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_07530 f7946b6aa3d0e5872fe7673ed71736b4 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 9.2E-5 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_07530 f7946b6aa3d0e5872fe7673ed71736b4 278 SUPERFAMILY SSF53474 1 269 1.65E-37 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_07530 f7946b6aa3d0e5872fe7673ed71736b4 278 Gene3D G3DSA:3.40.50.1820 1 271 1.4E-41 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_15990 b5c78357884caac820a7308036eb35ca 127 Pfam PF07009 NusG domain II 30 118 3.9E-15 T 13-10-2018 IPR024045 NusG, domain 2 THITH_15990 b5c78357884caac820a7308036eb35ca 127 Gene3D G3DSA:2.60.320.10 34 124 6.3E-15 T 13-10-2018 IPR038690 NusG, domain 2 superfamily THITH_05375 2eb940b507275bc3cdd9a57f629b12e9 167 Gene3D G3DSA:3.40.630.30 1 161 2.1E-43 T 13-10-2018 THITH_05375 2eb940b507275bc3cdd9a57f629b12e9 167 Pfam PF13508 Acetyltransferase (GNAT) domain 43 146 3.1E-8 T 13-10-2018 IPR000182 GNAT domain THITH_05375 2eb940b507275bc3cdd9a57f629b12e9 167 SUPERFAMILY SSF55729 23 152 1.12E-14 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_15280 5647480d161ce68a430830c924c938a9 157 Pfam PF04186 FxsA cytoplasmic membrane protein 10 116 2.0E-29 T 13-10-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 THITH_07205 8a3b4fe8f237cdd32539b558a199eab7 444 Pfam PF01420 Type I restriction modification DNA specificity domain 241 410 3.0E-8 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THITH_07205 8a3b4fe8f237cdd32539b558a199eab7 444 Pfam PF01420 Type I restriction modification DNA specificity domain 67 208 3.3E-4 T 13-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 THITH_07205 8a3b4fe8f237cdd32539b558a199eab7 444 SUPERFAMILY SSF116734 24 242 1.8E-32 T 13-10-2018 THITH_07205 8a3b4fe8f237cdd32539b558a199eab7 444 Gene3D G3DSA:3.90.220.20 411 430 5.4E-40 T 13-10-2018 THITH_07205 8a3b4fe8f237cdd32539b558a199eab7 444 Gene3D G3DSA:3.90.220.20 21 232 4.3E-22 T 13-10-2018 THITH_07205 8a3b4fe8f237cdd32539b558a199eab7 444 Gene3D G3DSA:3.90.220.20 241 410 5.4E-40 T 13-10-2018 THITH_07205 8a3b4fe8f237cdd32539b558a199eab7 444 SUPERFAMILY SSF116734 233 435 2.78E-32 T 13-10-2018 THITH_03825 8bd88f83f1c4901ec1e062ecf678d335 355 Pfam PF03739 Predicted permease YjgP/YjgQ family 7 351 6.2E-63 T 13-10-2018 IPR005495 Permease LptG/LptF-related GO:0016021 THITH_03825 8bd88f83f1c4901ec1e062ecf678d335 355 TIGRFAM TIGR04408 LptG_lptG: LPS export ABC transporter permease LptG 5 352 9.8E-109 T 13-10-2018 IPR030923 LPS export ABC transporter permease LptG GO:0043190|GO:0055085 THITH_17470 1976ed42a48eee69ef38c67ceecf1caf 119 Gene3D G3DSA:3.40.50.10580 12 78 3.8E-5 T 13-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_17470 1976ed42a48eee69ef38c67ceecf1caf 119 SUPERFAMILY SSF159468 14 104 1.44E-8 T 13-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_07570 b24b861b14635cf816a714a2e254e87e 122 SUPERFAMILY SSF69721 18 112 5.89E-18 T 13-10-2018 IPR025526 DsrC-like domain superfamily THITH_07570 b24b861b14635cf816a714a2e254e87e 122 Pfam PF04358 DsrC like protein 23 112 3.6E-20 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_07570 b24b861b14635cf816a714a2e254e87e 122 Gene3D G3DSA:1.10.10.370 43 114 1.4E-15 T 13-10-2018 THITH_07570 b24b861b14635cf816a714a2e254e87e 122 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 23 112 3.1E-17 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_07570 b24b861b14635cf816a714a2e254e87e 122 PIRSF PIRSF006223 7 114 5.8E-25 T 13-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE THITH_12395 d589905c87dc2bd2260f561cd2c242c0 102 Pfam PF12321 Protein of unknown function (DUF3634) 4 90 1.8E-15 T 13-10-2018 IPR022090 Protein of unknown function DUF3634 THITH_01495 50135764998b9ee5d475026782a32368 77 Pfam PF02597 ThiS family 5 77 1.2E-15 T 13-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 THITH_01495 50135764998b9ee5d475026782a32368 77 Gene3D G3DSA:3.10.20.30 2 77 1.9E-18 T 13-10-2018 IPR012675 Beta-grasp domain superfamily THITH_01495 50135764998b9ee5d475026782a32368 77 SUPERFAMILY SSF54285 2 75 1.85E-17 T 13-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp THITH_05475 8d69d50a738ab29e66d9b5d3ab9effcd 240 SUPERFAMILY SSF54001 53 132 1.49E-10 T 13-10-2018 IPR038765 Papain-like cysteine peptidase superfamily THITH_05475 8d69d50a738ab29e66d9b5d3ab9effcd 240 Gene3D G3DSA:3.10.620.30 34 232 7.6E-76 T 13-10-2018 THITH_05475 8d69d50a738ab29e66d9b5d3ab9effcd 240 Pfam PF06035 Bacterial transglutaminase-like cysteine proteinase BTLCP 66 183 1.7E-16 T 13-10-2018 IPR010319 Transglutaminase-like cysteine peptidase, predicted THITH_16540 2578c622436d7059130ad69353b1deff 205 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 4 196 1.0E-59 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 THITH_16540 2578c622436d7059130ad69353b1deff 205 Pfam PF02660 Glycerol-3-phosphate acyltransferase 10 186 7.4E-49 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 THITH_16540 2578c622436d7059130ad69353b1deff 205 SMART SM01207 9 187 2.2E-83 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 THITH_16540 2578c622436d7059130ad69353b1deff 205 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 6 195 20.452 T 13-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 THITH_13705 566d984d4eb1ca58c28950e06a611d09 258 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 5 164 6.3E-16 T 13-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase THITH_06475 171bcf9d41865932a0f33309d028e9f9 280 Gene3D G3DSA:3.40.50.700 22 187 8.8E-40 T 13-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily THITH_06475 171bcf9d41865932a0f33309d028e9f9 280 SUPERFAMILY SSF56770 22 238 2.75E-45 T 13-10-2018 THITH_06475 171bcf9d41865932a0f33309d028e9f9 280 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 34 173 1.7E-25 T 13-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_16840 710a8731b2f137e756891d2eb3725711 317 Pfam PF12849 PBP superfamily domain 71 286 2.2E-12 T 13-10-2018 IPR024370 PBP domain THITH_16840 710a8731b2f137e756891d2eb3725711 317 Gene3D G3DSA:3.40.190.10 73 293 6.5E-39 T 13-10-2018 THITH_16840 710a8731b2f137e756891d2eb3725711 317 SUPERFAMILY SSF53850 71 302 9.9E-37 T 13-10-2018 THITH_16840 710a8731b2f137e756891d2eb3725711 317 Gene3D G3DSA:3.40.190.10 132 263 6.5E-39 T 13-10-2018 THITH_15670 b6a6c2b1d8983f3060ce025b231e8147 223 Pfam PF04002 RadC-like JAB domain 103 222 2.4E-42 T 13-10-2018 IPR025657 RadC-like JAB domain THITH_15670 b6a6c2b1d8983f3060ce025b231e8147 223 SUPERFAMILY SSF47781 18 90 6.23E-10 T 13-10-2018 IPR010994 RuvA domain 2-like THITH_15670 b6a6c2b1d8983f3060ce025b231e8147 223 SUPERFAMILY SSF102712 109 191 8.5E-6 T 13-10-2018 THITH_15670 b6a6c2b1d8983f3060ce025b231e8147 223 Gene3D G3DSA:3.40.140.10 101 223 1.3E-40 T 13-10-2018 THITH_15670 b6a6c2b1d8983f3060ce025b231e8147 223 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 223 7.6E-70 T 13-10-2018 IPR001405 Uncharacterised protein family UPF0758 THITH_15670 b6a6c2b1d8983f3060ce025b231e8147 223 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 13-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site THITH_03460 777f2e2f19c2f4261be9fdf2d17b1346 195 SUPERFAMILY SSF53955 14 155 1.55E-17 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily THITH_03460 777f2e2f19c2f4261be9fdf2d17b1346 195 Gene3D G3DSA:1.10.530.10 23 183 4.0E-12 T 13-10-2018 THITH_08370 cbec066e260f1bf874d5fb5daec27e77 195 SUPERFAMILY SSF51604 1 172 3.98E-37 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily THITH_08370 cbec066e260f1bf874d5fb5daec27e77 195 Pfam PF13378 Enolase C-terminal domain-like 1 148 2.0E-17 T 13-10-2018 IPR029065 Enolase C-terminal domain-like THITH_08370 cbec066e260f1bf874d5fb5daec27e77 195 SMART SM00922 10 78 5.6E-6 T 13-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal THITH_08370 cbec066e260f1bf874d5fb5daec27e77 195 Gene3D G3DSA:3.20.20.120 1 161 4.0E-43 T 13-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily THITH_08370 cbec066e260f1bf874d5fb5daec27e77 195 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 30 61 - T 13-10-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 THITH_08495 5fd1b671324f9d6a106bb39d477faebd 381 SUPERFAMILY SSF56059 159 349 5.63E-11 T 13-10-2018 THITH_08495 5fd1b671324f9d6a106bb39d477faebd 381 Pfam PF14397 Sugar-transfer associated ATP-grasp 159 352 4.4E-32 T 13-10-2018 IPR039523 Alpha-L-glutamate ligase-related protein, ATP-grasp domain KEGG: 00270+6.3.2.2+6.3.2.3|KEGG: 00480+6.3.2.2+6.3.2.3|MetaCyc: PWY-6840|MetaCyc: PWY-7255 THITH_16435 abc5c6540450775ab05f1cae456777f8 199 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 134 140 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THITH_16435 abc5c6540450775ab05f1cae456777f8 199 Pfam PF03602 Conserved hypothetical protein 95 17 189 1.5E-48 T 13-10-2018 THITH_16435 abc5c6540450775ab05f1cae456777f8 199 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 16 190 3.3E-45 T 13-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 THITH_16435 abc5c6540450775ab05f1cae456777f8 199 Gene3D G3DSA:3.40.50.150 10 198 3.3E-54 T 13-10-2018 THITH_16435 abc5c6540450775ab05f1cae456777f8 199 SUPERFAMILY SSF53335 17 188 1.75E-43 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_16435 abc5c6540450775ab05f1cae456777f8 199 PIRSF PIRSF004553 16 197 1.2E-42 T 13-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 THITH_09850 071e86bbe606789b9abf8d7c6048deaa 186 Gene3D G3DSA:3.40.50.150 8 177 1.8E-22 T 13-10-2018 THITH_09850 071e86bbe606789b9abf8d7c6048deaa 186 SUPERFAMILY SSF53335 13 174 9.83E-23 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_09850 071e86bbe606789b9abf8d7c6048deaa 186 Pfam PF13489 Methyltransferase domain 24 164 4.0E-11 T 13-10-2018 THITH_13330 c914c8c3de400d4a3f7acff4930a66dc 395 Pfam PF02687 FtsX-like permease family 287 371 1.3E-10 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THITH_13330 c914c8c3de400d4a3f7acff4930a66dc 395 Pfam PF12704 MacB-like periplasmic core domain 13 232 9.9E-12 T 13-10-2018 IPR025857 MacB-like periplasmic core domain THITH_00855 788b417c1f803aa8e7317aaa3282b103 219 SUPERFAMILY SSF55729 3 124 4.77E-11 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_00855 788b417c1f803aa8e7317aaa3282b103 219 Gene3D G3DSA:3.40.630.30 1 215 1.8E-35 T 13-10-2018 THITH_07650 1b269bed9b14c9ef6b7b5cfc5b65be30 123 Pfam PF17228 Sulphur globule protein 26 122 6.5E-18 T 13-10-2018 IPR035173 Sulphur globule protein THITH_07540 581566e5dc51a70bc42b18e88f06e22d 290 SUPERFAMILY SSF51695 14 256 3.66E-35 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 THITH_07540 581566e5dc51a70bc42b18e88f06e22d 290 Gene3D G3DSA:3.20.20.190 10 261 5.0E-38 T 13-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 THITH_07540 581566e5dc51a70bc42b18e88f06e22d 290 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 20 91 6.1E-23 T 13-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 THITH_10610 6df0bbfe3c65e22f9ece017ba5f27b67 88 SUPERFAMILY SSF64307 3 68 3.4E-8 T 13-10-2018 IPR036868 TusA-like domain superfamily THITH_10610 6df0bbfe3c65e22f9ece017ba5f27b67 88 Pfam PF10006 Uncharacterized conserved protein (DUF2249) 5 70 5.0E-16 T 13-10-2018 IPR018720 Domain of unknown function DUF2249 THITH_00885 3d0551095507547c2dab08f943ae2079 212 SUPERFAMILY SSF103196 94 152 3.14E-6 T 13-10-2018 THITH_13710 e540ea220d027c4c756208d8e37cbaf2 146 PRINTS PR01021 OMPA domain signature 85 101 3.5E-13 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THITH_13710 e540ea220d027c4c756208d8e37cbaf2 146 PRINTS PR01021 OMPA domain signature 40 62 3.5E-13 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THITH_13710 e540ea220d027c4c756208d8e37cbaf2 146 PRINTS PR01021 OMPA domain signature 70 85 3.5E-13 T 13-10-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 THITH_13710 e540ea220d027c4c756208d8e37cbaf2 146 Pfam PF00691 OmpA family 39 134 3.1E-21 T 13-10-2018 IPR006665 OmpA-like domain THITH_13710 e540ea220d027c4c756208d8e37cbaf2 146 Gene3D G3DSA:3.30.1330.60 3 145 5.5E-43 T 13-10-2018 IPR036737 OmpA-like domain superfamily THITH_13710 e540ea220d027c4c756208d8e37cbaf2 146 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 56 82 3.3E-10 T 13-10-2018 THITH_13710 e540ea220d027c4c756208d8e37cbaf2 146 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 85 102 3.3E-10 T 13-10-2018 THITH_13710 e540ea220d027c4c756208d8e37cbaf2 146 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 103 122 3.3E-10 T 13-10-2018 THITH_13710 e540ea220d027c4c756208d8e37cbaf2 146 PRINTS PR01023 Sodium-type flagellar protein MotY precursor signature 123 143 3.3E-10 T 13-10-2018 THITH_13710 e540ea220d027c4c756208d8e37cbaf2 146 SUPERFAMILY SSF103088 27 142 9.94E-37 T 13-10-2018 IPR036737 OmpA-like domain superfamily THITH_13230 b09f0b03fdf9f810f34f9a8070249d62 236 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 27 236 37.713 T 13-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 THITH_13230 b09f0b03fdf9f810f34f9a8070249d62 236 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 30 234 3.8E-66 T 13-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 THITH_13230 b09f0b03fdf9f810f34f9a8070249d62 236 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 157 172 - T 13-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 THITH_13230 b09f0b03fdf9f810f34f9a8070249d62 236 SUPERFAMILY SSF53335 28 232 1.22E-53 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_13230 b09f0b03fdf9f810f34f9a8070249d62 236 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 33 234 4.8E-64 T 13-10-2018 THITH_13230 b09f0b03fdf9f810f34f9a8070249d62 236 Gene3D G3DSA:3.40.50.150 17 235 6.6E-86 T 13-10-2018 THITH_09015 bbe45d468f5587ce904b1bf80a98e4f8 109 Pfam PF14110 Domain of unknown function (DUF4282) 13 104 1.0E-10 T 13-10-2018 IPR025557 Protein of unknown function DUF4282 THITH_09815 12704f43fe7eac603e63b6cfc5e355b8 423 SUPERFAMILY SSF49265 160 251 3.77E-9 T 13-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 THITH_09815 12704f43fe7eac603e63b6cfc5e355b8 423 Pfam PF07603 Protein of unknown function (DUF1566) 273 415 5.8E-17 T 13-10-2018 IPR011460 Protein of unknown function DUF1566 THITH_09815 12704f43fe7eac603e63b6cfc5e355b8 423 Gene3D G3DSA:2.60.40.10 161 255 2.6E-13 T 13-10-2018 IPR013783 Immunoglobulin-like fold THITH_15695 b801d31e83756088fe1be1357970782d 253 Pfam PF01925 Sulfite exporter TauE/SafE 9 247 1.1E-36 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 THITH_02130 f9e9fc990a69a1ad27262a54df7a5948 256 Pfam PF11748 Protein of unknown function (DUF3306) 18 134 1.0E-27 T 13-10-2018 IPR021735 Protein of unknown function DUF3306 THITH_01725 418aec23fb15cd1d043679bfaa294d58 287 Pfam PF13230 Glutamine amidotransferases class-II 1 272 1.6E-65 T 13-10-2018 IPR026869 Putative glutamine amidotransferase type 2 THITH_01725 418aec23fb15cd1d043679bfaa294d58 287 Gene3D G3DSA:3.60.20.10 1 274 3.7E-77 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_01725 418aec23fb15cd1d043679bfaa294d58 287 SUPERFAMILY SSF56235 2 190 4.05E-29 T 13-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal THITH_09425 b30c1bb135076eaa4d8ea906cb477fc2 84 Pfam PF03937 Flavinator of succinate dehydrogenase 5 64 3.9E-21 T 13-10-2018 IPR005631 Flavinator of succinate dehydrogenase THITH_09425 b30c1bb135076eaa4d8ea906cb477fc2 84 SUPERFAMILY SSF109910 5 75 1.44E-18 T 13-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily THITH_09425 b30c1bb135076eaa4d8ea906cb477fc2 84 Gene3D G3DSA:1.10.150.250 1 82 1.0E-24 T 13-10-2018 IPR036714 Flavinator of succinate dehydrogenase superfamily THITH_08365 4ba3cc6b66a73b76b970acaccf495201 453 Pfam PF13193 AMP-binding enzyme C-terminal domain 369 429 2.4E-10 T 13-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain THITH_08365 4ba3cc6b66a73b76b970acaccf495201 453 Gene3D G3DSA:3.40.50.12780 2 356 2.2E-64 T 13-10-2018 THITH_08365 4ba3cc6b66a73b76b970acaccf495201 453 Pfam PF00501 AMP-binding enzyme 12 358 5.1E-42 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 THITH_08365 4ba3cc6b66a73b76b970acaccf495201 453 SUPERFAMILY SSF56801 9 450 1.31E-90 T 13-10-2018 THITH_08365 4ba3cc6b66a73b76b970acaccf495201 453 Gene3D G3DSA:3.30.300.30 358 451 1.2E-19 T 13-10-2018 THITH_13795 5dfc40dd9bf42e6d933588aa3b759c98 149 Pfam PF02517 CAAX protease self-immunity 47 141 7.1E-22 T 13-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 THITH_00065 e446fdb6e1dc77bab54085abea456e52 279 Gene3D G3DSA:3.40.50.10090 17 254 7.1E-69 T 13-10-2018 THITH_00065 e446fdb6e1dc77bab54085abea456e52 279 SUPERFAMILY SSF69618 14 261 1.26E-57 T 13-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THITH_00065 e446fdb6e1dc77bab54085abea456e52 279 Pfam PF02602 Uroporphyrinogen-III synthase HemD 31 255 5.0E-45 T 13-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 THITH_00065 e446fdb6e1dc77bab54085abea456e52 279 Gene3D G3DSA:3.40.50.10090 46 178 7.1E-69 T 13-10-2018 THITH_13225 0ac401da5cde359808a6de6f53ccca05 799 Gene3D G3DSA:3.40.50.150 303 499 8.1E-16 T 13-10-2018 THITH_13225 0ac401da5cde359808a6de6f53ccca05 799 SUPERFAMILY SSF53335 227 442 4.72E-12 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_14940 326db97e842f0db5de8e7fd076afeea4 265 Pfam PF00005 ABC transporter 26 171 3.2E-30 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_14940 326db97e842f0db5de8e7fd076afeea4 265 Gene3D G3DSA:3.40.50.300 11 248 7.2E-56 T 13-10-2018 THITH_14940 326db97e842f0db5de8e7fd076afeea4 265 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_14940 326db97e842f0db5de8e7fd076afeea4 265 SUPERFAMILY SSF52540 5 214 5.87E-51 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14940 326db97e842f0db5de8e7fd076afeea4 265 SMART SM00382 31 218 2.3E-14 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_12955 3b5778aeb262d90501085eb5bf7da197 350 Pfam PF00146 NADH dehydrogenase 17 336 4.9E-131 T 13-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12955 3b5778aeb262d90501085eb5bf7da197 350 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 10 344 26.086 T 13-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12955 3b5778aeb262d90501085eb5bf7da197 350 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 214 227 - T 13-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_02400 5672293bbd90c73812e69c07d9e9217c 509 Pfam PF14400 Inactive transglutaminase fused to 7 transmembrane helices 23 181 4.8E-46 T 13-10-2018 IPR025838 Inactive transglutaminase fused to 7 transmembrane helices THITH_02400 5672293bbd90c73812e69c07d9e9217c 509 Pfam PF14402 7 transmembrane helices usually fused to an inactive transglutaminase 259 503 2.4E-105 T 13-10-2018 IPR025840 7 transmembrane helices usually fused to an inactive transglutaminase THITH_02190 5000e31a2d861ac2c9a703673862f08f 71 Gene3D G3DSA:3.30.2310.20 1 71 4.0E-15 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_02190 5000e31a2d861ac2c9a703673862f08f 71 SUPERFAMILY SSF143011 2 69 6.41E-14 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_02190 5000e31a2d861ac2c9a703673862f08f 71 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 7 65 1.3E-5 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THITH_05185 ada20f276c4a13056a574d1a77fba3ee 236 Pfam PF01881 CRISPR associated protein Cas6 110 231 1.0E-8 T 13-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 THITH_03920 a49abf621f9df5c140c4e8222848d69a 254 Gene3D G3DSA:3.60.21.10 7 232 9.6E-10 T 13-10-2018 IPR029052 Metallo-dependent phosphatase-like THITH_03920 a49abf621f9df5c140c4e8222848d69a 254 TIGRFAM TIGR01854 lipid_A_lpxH: UDP-2,3-diacylglucosamine diphosphatase 8 233 4.6E-69 T 13-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 THITH_03920 a49abf621f9df5c140c4e8222848d69a 254 SUPERFAMILY SSF56300 7 221 1.49E-24 T 13-10-2018 THITH_03920 a49abf621f9df5c140c4e8222848d69a 254 Pfam PF00149 Calcineurin-like phosphoesterase 6 200 1.1E-6 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THITH_03920 a49abf621f9df5c140c4e8222848d69a 254 Hamap MF_00575 UDP-2,3-diacylglucosamine hydrolase [lpxH]. 1 242 88.414 T 13-10-2018 IPR010138 UDP-2,3-diacylglucosamine hydrolase GO:0005737|GO:0009245|GO:0016462 KEGG: 00540+3.6.1.54 THITH_03875 cbda793f4752ef58f5c052c5ef5b3c4b 134 Pfam PF13767 Domain of unknown function (DUF4168) 51 126 1.9E-17 T 13-10-2018 IPR025433 Domain of unknown function DUF4168 THITH_14845 adebe30fd5ac0dd44d56a772de59f088 352 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 16 334 3.1E-22 T 13-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 THITH_14845 adebe30fd5ac0dd44d56a772de59f088 352 Gene3D G3DSA:3.40.720.10 4 345 8.1E-30 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 THITH_14845 adebe30fd5ac0dd44d56a772de59f088 352 SUPERFAMILY SSF53649 9 348 4.8E-37 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 THITH_00550 467f6cee26fd4b1a75d9aa61edcf4106 569 TIGRFAM TIGR01982 UbiB: 2-polyprenylphenol 6-hydroxylase 10 445 1.0E-171 T 13-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 THITH_00550 467f6cee26fd4b1a75d9aa61edcf4106 569 Hamap MF_00414 Probable protein kinase UbiB [ubiB]. 5 550 50.864 T 13-10-2018 IPR010232 Probable protein kinase UbiB GO:0006744 THITH_00550 467f6cee26fd4b1a75d9aa61edcf4106 569 Pfam PF03109 ABC1 family 114 231 4.4E-33 T 13-10-2018 IPR004147 UbiB domain THITH_00550 467f6cee26fd4b1a75d9aa61edcf4106 569 SUPERFAMILY SSF56112 96 437 1.33E-47 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily THITH_00720 36d718d9ff8178cdcfac672f325e1d64 253 Pfam PF01694 Rhomboid family 59 195 1.4E-16 T 13-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 THITH_00720 36d718d9ff8178cdcfac672f325e1d64 253 Gene3D G3DSA:1.20.1540.10 21 199 2.7E-10 T 13-10-2018 IPR035952 Rhomboid-like superfamily THITH_00720 36d718d9ff8178cdcfac672f325e1d64 253 SUPERFAMILY SSF144091 22 197 1.03E-20 T 13-10-2018 THITH_13940 2e6f316afbf2936bed68a3f481959296 466 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 8 434 1.0E-162 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 THITH_13940 2e6f316afbf2936bed68a3f481959296 466 PIRSF PIRSF006446 1 458 4.6E-186 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 THITH_13940 2e6f316afbf2936bed68a3f481959296 466 SUPERFAMILY SSF161098 317 439 2.29E-5 T 13-10-2018 IPR035906 MetI-like superfamily THITH_10900 9617203322cd34031976ff58bed516c5 428 Gene3D G3DSA:3.40.190.10 23 420 2.8E-64 T 13-10-2018 THITH_10900 9617203322cd34031976ff58bed516c5 428 SUPERFAMILY SSF53850 29 410 3.26E-58 T 13-10-2018 THITH_10900 9617203322cd34031976ff58bed516c5 428 Pfam PF13416 Bacterial extracellular solute-binding protein 48 348 2.7E-22 T 13-10-2018 IPR006059 Bacterial extracellular solute-binding protein THITH_16685 7e8a4a7a8fa9db44dd41372a8388f517 154 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 17 146 3.9E-28 T 13-10-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like THITH_16685 7e8a4a7a8fa9db44dd41372a8388f517 154 SUPERFAMILY SSF55961 4 148 3.81E-43 T 13-10-2018 THITH_16685 7e8a4a7a8fa9db44dd41372a8388f517 154 Gene3D G3DSA:3.30.530.20 7 151 5.7E-39 T 13-10-2018 IPR023393 START-like domain superfamily THITH_01740 6aa6daec45fd9d4a3069ba72a5441233 403 SUPERFAMILY SSF56935 35 380 9.16E-22 T 13-10-2018 THITH_16695 560ed9a40a017b3e6499416844ecf185 127 Gene3D G3DSA:3.10.180.10 6 126 1.5E-26 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THITH_16695 560ed9a40a017b3e6499416844ecf185 127 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 9 121 4.5E-6 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain THITH_16695 560ed9a40a017b3e6499416844ecf185 127 SUPERFAMILY SSF54593 6 126 2.61E-21 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THITH_11880 9d032a1dd0143485a10a50e55996cd94 604 Pfam PF00501 AMP-binding enzyme 18 470 5.9E-100 T 13-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 THITH_11880 9d032a1dd0143485a10a50e55996cd94 604 Gene3D G3DSA:3.40.50.12780 8 303 4.6E-58 T 13-10-2018 THITH_11880 9d032a1dd0143485a10a50e55996cd94 604 SUPERFAMILY SSF56801 9 599 8.63E-126 T 13-10-2018 THITH_11880 9d032a1dd0143485a10a50e55996cd94 604 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 13-10-2018 IPR020845 AMP-binding, conserved site THITH_11880 9d032a1dd0143485a10a50e55996cd94 604 Gene3D G3DSA:3.40.50.12780 325 463 1.3E-41 T 13-10-2018 THITH_15215 07c7f13231cad8a0b3460bfb623cfcfe 1373 Pfam PF04357 TamB, inner membrane protein subunit of TAM complex 1041 1372 1.5E-58 T 13-10-2018 IPR007452 Translocation and assembly module TamB THITH_05040 10b8a56573077ea72487ee574de97946 201 Pfam PF08745 PINc domain ribonuclease 3 188 7.6E-61 T 13-10-2018 IPR014856 PIN-domain ribonuclease THITH_05040 10b8a56573077ea72487ee574de97946 201 Hamap MF_01078 UPF0278 protein . 1 192 29.581 T 13-10-2018 IPR014856 PIN-domain ribonuclease THITH_05040 10b8a56573077ea72487ee574de97946 201 TIGRFAM TIGR03875 RNA_lig_partner: RNA ligase partner, MJ_0950 family 3 188 2.2E-66 T 13-10-2018 IPR014856 PIN-domain ribonuclease THITH_15660 a3b491ff71a1f525c80a5f0ccc6cdd91 153 Pfam PF13686 DsrE/DsrF/DrsH-like family 4 152 2.6E-45 T 13-10-2018 IPR032836 DsrE2-like family THITH_15660 a3b491ff71a1f525c80a5f0ccc6cdd91 153 SUPERFAMILY SSF75169 5 152 3.53E-18 T 13-10-2018 IPR027396 DsrEFH-like THITH_15660 a3b491ff71a1f525c80a5f0ccc6cdd91 153 Gene3D G3DSA:3.40.1260.10 2 153 1.2E-36 T 13-10-2018 IPR027396 DsrEFH-like THITH_15225 19b8f530aec485d105e0fd176bbd458d 374 Pfam PF02687 FtsX-like permease family 266 366 1.3E-13 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THITH_13245 1274955d2c19ce3b9b0fb3130e56e5c6 422 SUPERFAMILY SSF56935 95 397 3.92E-11 T 13-10-2018 THITH_01370 1d39d083b5269efd8166eef15ef117c0 327 Pfam PF04976 DMSO reductase anchor subunit (DmsC) 1 320 1.9E-30 T 13-10-2018 IPR007059 DMSO reductase anchor subunit (DmsC) GO:0016021|GO:0019645 THITH_09300 c189f0c740924a5de90d8f8498f71ca4 418 Pfam PF03787 RAMP superfamily 35 210 1.2E-10 T 13-10-2018 IPR005537 CRISPR type III-associated RAMP protein THITH_09300 c189f0c740924a5de90d8f8498f71ca4 418 TIGRFAM TIGR01894 cas_TM1795_cmr1: CRISPR type III-B/RAMP module RAMP protein Cmr1 35 114 5.8E-8 T 13-10-2018 IPR007522 CRISPR-associated protein TM1795 THITH_10325 24a088fe41de58687b6fec7ab7bf5ac9 515 Pfam PF00361 Proton-conducting membrane transporter 131 415 4.2E-77 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10325 24a088fe41de58687b6fec7ab7bf5ac9 515 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 7 503 2.9E-170 T 13-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10325 24a088fe41de58687b6fec7ab7bf5ac9 515 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 382 408 1.3E-43 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10325 24a088fe41de58687b6fec7ab7bf5ac9 515 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 242 266 1.3E-43 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10325 24a088fe41de58687b6fec7ab7bf5ac9 515 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 137 156 1.3E-43 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10325 24a088fe41de58687b6fec7ab7bf5ac9 515 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 330 349 1.3E-43 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_10325 24a088fe41de58687b6fec7ab7bf5ac9 515 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 167 191 1.3E-43 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_01840 8c5f25982dcab70305d55a132fcd4762 204 Gene3D G3DSA:3.40.50.300 2 102 2.5E-12 T 13-10-2018 THITH_01840 8c5f25982dcab70305d55a132fcd4762 204 SUPERFAMILY SSF52540 18 188 1.81E-29 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_01840 8c5f25982dcab70305d55a132fcd4762 204 SMART SM00382 31 202 9.3E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_01840 8c5f25982dcab70305d55a132fcd4762 204 Gene3D G3DSA:3.40.50.300 103 195 4.7E-18 T 13-10-2018 THITH_01840 8c5f25982dcab70305d55a132fcd4762 204 Pfam PF00005 ABC transporter 25 67 1.8E-8 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_01840 8c5f25982dcab70305d55a132fcd4762 204 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 111 188 5.9E-9 T 13-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 THITH_11325 01d3b46a940a0391429cfffab309c3a5 575 Pfam PF07885 Ion channel 26 100 4.7E-7 T 13-10-2018 IPR013099 Potassium channel domain THITH_11325 01d3b46a940a0391429cfffab309c3a5 575 SUPERFAMILY SSF51735 286 418 6.06E-24 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_11325 01d3b46a940a0391429cfffab309c3a5 575 Gene3D G3DSA:3.40.50.720 286 416 1.0E-22 T 13-10-2018 THITH_11325 01d3b46a940a0391429cfffab309c3a5 575 Gene3D G3DSA:3.40.50.720 121 265 9.7E-31 T 13-10-2018 THITH_11325 01d3b46a940a0391429cfffab309c3a5 575 SUPERFAMILY SSF81324 10 145 1.05E-11 T 13-10-2018 THITH_11325 01d3b46a940a0391429cfffab309c3a5 575 SUPERFAMILY SSF51735 125 263 8.49E-26 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_11325 01d3b46a940a0391429cfffab309c3a5 575 Pfam PF02254 TrkA-N domain 291 398 1.0E-16 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 THITH_11325 01d3b46a940a0391429cfffab309c3a5 575 Pfam PF02254 TrkA-N domain 126 247 3.9E-23 T 13-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 THITH_11325 01d3b46a940a0391429cfffab309c3a5 575 Gene3D G3DSA:1.10.287.70 2 103 1.4E-5 T 13-10-2018 THITH_00225 b4d97029b859bf30f2127b7f5152f75d 80 SUPERFAMILY SSF143011 9 75 4.32E-16 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_00225 b4d97029b859bf30f2127b7f5152f75d 80 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 16 75 8.2E-11 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THITH_00225 b4d97029b859bf30f2127b7f5152f75d 80 Gene3D G3DSA:3.30.2310.20 2 79 8.9E-17 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_15310 b7a3f553af361dbd7baa77a115521aa6 130 Gene3D G3DSA:3.40.30.10 2 129 9.9E-37 T 13-10-2018 THITH_15310 b7a3f553af361dbd7baa77a115521aa6 130 Pfam PF00578 AhpC/TSA family 1 111 4.4E-22 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THITH_15310 b7a3f553af361dbd7baa77a115521aa6 130 ProSitePatterns PS00194 Thioredoxin family active site. 20 38 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 THITH_15310 b7a3f553af361dbd7baa77a115521aa6 130 SUPERFAMILY SSF52833 1 130 5.41E-32 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_15070 bacad8421631830fb149e3bfcb72c44b 108 SUPERFAMILY SSF47413 37 93 1.35E-7 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 THITH_15070 bacad8421631830fb149e3bfcb72c44b 108 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 5 94 1.6E-35 T 13-10-2018 IPR014057 Uncharacterized protein HI1420 THITH_04575 4903855efc99511efe7be9e87c2c4d1e 30 Gene3D G3DSA:3.30.2310.20 1 29 2.2E-6 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_09895 b560f1679b8a9dd23fc3880903dc44c6 299 SUPERFAMILY SSF51735 3 294 1.59E-67 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_09895 b560f1679b8a9dd23fc3880903dc44c6 299 Gene3D G3DSA:3.40.50.720 6 282 1.8E-90 T 13-10-2018 THITH_09895 b560f1679b8a9dd23fc3880903dc44c6 299 Pfam PF16363 GDP-mannose 4,6 dehydratase 7 288 8.4E-41 T 13-10-2018 IPR016040 NAD(P)-binding domain THITH_09895 b560f1679b8a9dd23fc3880903dc44c6 299 Gene3D G3DSA:3.90.25.10 171 289 1.8E-90 T 13-10-2018 THITH_11030 63a60005c6bf65a6160f2b1abe1178ae 81 Pfam PF06305 Lipopolysaccharide assembly protein A domain 22 65 6.1E-6 T 13-10-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 THITH_04140 c2c79651bc7f26e74773f5e4885be2e4 99 Pfam PF03334 Na+/H+ antiporter subunit 11 89 1.4E-23 T 13-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 THITH_04140 c2c79651bc7f26e74773f5e4885be2e4 99 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 11 97 7.1E-20 T 13-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 THITH_00780 c4522af4bc1ef82e1c1ff28daee52e18 217 Pfam PF02589 LUD domain 126 216 7.2E-20 T 13-10-2018 IPR003741 LUD domain THITH_00780 c4522af4bc1ef82e1c1ff28daee52e18 217 Gene3D G3DSA:3.40.50.10420 46 217 1.2E-38 T 13-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily THITH_00780 c4522af4bc1ef82e1c1ff28daee52e18 217 SUPERFAMILY SSF100950 45 217 1.34E-35 T 13-10-2018 IPR037171 NagB/RpiA transferase-like THITH_00710 cc555d9d951af5c3572312a3f44a5d01 157 Gene3D G3DSA:1.20.120.10 31 155 8.0E-31 T 13-10-2018 THITH_00710 cc555d9d951af5c3572312a3f44a5d01 157 PIRSF PIRSF000027 12 156 3.8E-25 T 13-10-2018 IPR012127 Cytochrome c prime GO:0005506|GO:0009055|GO:0020037|GO:0042597 THITH_00710 cc555d9d951af5c3572312a3f44a5d01 157 SUPERFAMILY SSF47175 33 155 1.77E-27 T 13-10-2018 IPR010980 Cytochrome c/b562 GO:0005506|GO:0009055|GO:0020037|GO:0022900 THITH_00710 cc555d9d951af5c3572312a3f44a5d01 157 Pfam PF01322 Cytochrome C' 37 154 9.5E-29 T 13-10-2018 IPR002321 Cytochrome c, class II GO:0005506|GO:0009055|GO:0020037 THITH_00710 cc555d9d951af5c3572312a3f44a5d01 157 PRINTS PR00608 Class II cytochrome C signature 143 154 3.2E-5 T 13-10-2018 IPR015984 Cytochrome c prime, subgroup THITH_00710 cc555d9d951af5c3572312a3f44a5d01 157 PRINTS PR00608 Class II cytochrome C signature 120 143 3.2E-5 T 13-10-2018 IPR015984 Cytochrome c prime, subgroup THITH_10935 e8eae85d4035c56a2bb918201096b9b5 375 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 303 2.1E-14 T 13-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 THITH_10935 e8eae85d4035c56a2bb918201096b9b5 375 SUPERFAMILY SSF51905 1 328 8.2E-23 T 13-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily THITH_10935 e8eae85d4035c56a2bb918201096b9b5 375 Gene3D G3DSA:3.50.50.100 1 375 5.8E-78 T 13-10-2018 THITH_08270 f7a98a64f0e704bf74411297dbb2f1ac 306 SUPERFAMILY SSF52540 180 261 8.57E-8 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_08270 f7a98a64f0e704bf74411297dbb2f1ac 306 Pfam PF13271 Domain of unknown function (DUF4062) 3 86 1.6E-21 T 13-10-2018 IPR025139 Domain of unknown function DUF4062 THITH_16885 8b43aea008bb57c8ce718af6689061ec 183 Gene3D G3DSA:2.30.30.40 119 174 6.7E-8 T 13-10-2018 THITH_16885 8b43aea008bb57c8ce718af6689061ec 183 Pfam PF08239 Bacterial SH3 domain 123 172 1.2E-9 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type THITH_05000 74d847d4fdf28d140e68188f0ad52726 404 SUPERFAMILY SSF103473 16 397 8.11E-23 T 13-10-2018 IPR036259 MFS transporter superfamily THITH_05000 74d847d4fdf28d140e68188f0ad52726 404 Gene3D G3DSA:1.20.1250.20 11 394 8.0E-19 T 13-10-2018 THITH_05000 74d847d4fdf28d140e68188f0ad52726 404 Pfam PF07690 Major Facilitator Superfamily 24 328 2.7E-8 T 13-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 THITH_06275 6decd0f3b80e96440525d55063b66970 335 SUPERFAMILY SSF53067 4 327 1.36E-45 T 13-10-2018 THITH_06275 6decd0f3b80e96440525d55063b66970 335 Gene3D G3DSA:3.30.420.40 3 321 6.0E-87 T 13-10-2018 THITH_06275 6decd0f3b80e96440525d55063b66970 335 Pfam PF02685 Glucokinase 5 326 9.3E-79 T 13-10-2018 IPR003836 Glucokinase GO:0004340|GO:0005524|GO:0005536|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 THITH_06275 6decd0f3b80e96440525d55063b66970 335 Gene3D G3DSA:3.40.367.20 107 310 6.0E-87 T 13-10-2018 THITH_03645 8b238bd72c2f50b4b35e2401947a546e 255 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 63 85 - T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THITH_03645 8b238bd72c2f50b4b35e2401947a546e 255 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 30 192 6.1E-34 T 13-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 THITH_03645 8b238bd72c2f50b4b35e2401947a546e 255 Pfam PF01066 CDP-alcohol phosphatidyltransferase 22 85 1.3E-12 T 13-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 THITH_03645 8b238bd72c2f50b4b35e2401947a546e 255 Gene3D G3DSA:1.20.120.1760 16 193 5.8E-14 T 13-10-2018 THITH_05665 350d67676a4b964fe8646d6864271eae 100 SUPERFAMILY SSF46785 2 94 5.47E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_05665 350d67676a4b964fe8646d6864271eae 100 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 40 2.4E-11 T 13-10-2018 THITH_05665 350d67676a4b964fe8646d6864271eae 100 TIGRFAM TIGR04176 MarR_EPS: EPS-associated transcriptional regulator, MarR family 1 95 4.8E-43 T 13-10-2018 IPR026433 EPS-associated transcriptional regulator, MarR family THITH_05665 350d67676a4b964fe8646d6864271eae 100 Gene3D G3DSA:1.10.10.10 1 98 2.2E-14 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_14445 cd61e47baf46eef2cc557acf5e176e59 265 Gene3D G3DSA:3.10.20.310 54 122 1.8E-17 T 13-10-2018 THITH_14445 cd61e47baf46eef2cc557acf5e176e59 265 Gene3D G3DSA:3.40.50.11690 124 253 3.3E-31 T 13-10-2018 THITH_14445 cd61e47baf46eef2cc557acf5e176e59 265 Pfam PF03799 Cell division protein FtsQ 127 240 1.1E-16 T 13-10-2018 IPR005548 Cell division protein FtsQ/DivIB THITH_14445 cd61e47baf46eef2cc557acf5e176e59 265 Pfam PF08478 POTRA domain, FtsQ-type 57 122 7.3E-14 T 13-10-2018 IPR013685 POTRA domain, FtsQ-type THITH_14445 cd61e47baf46eef2cc557acf5e176e59 265 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 26 248 21.137 T 13-10-2018 IPR026579 Cell division protein FtsQ GO:0090529 THITH_14615 afd34321b4fcb4556463847c68ed7967 260 TIGRFAM TIGR00056 TIGR00056: ABC transport permease subunit 16 257 5.9E-85 T 13-10-2018 IPR003453 ABC transport permease subunit MlaE, Proteobacteria THITH_14615 afd34321b4fcb4556463847c68ed7967 260 Pfam PF02405 Permease MlaE 44 253 2.8E-74 T 13-10-2018 IPR030802 ABC transporter permease MalE GO:0043190 THITH_06310 12412370caebb0c69fdc2f02f0e491b5 372 TIGRFAM TIGR02210 rodA_shape: rod shape-determining protein RodA 22 367 9.1E-136 T 13-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_06310 12412370caebb0c69fdc2f02f0e491b5 372 Hamap MF_02079 Peptidoglycan glycosyltransferase MrdB [mrdB]. 17 370 28.233 T 13-10-2018 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB GO:0008360|GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_06310 12412370caebb0c69fdc2f02f0e491b5 372 Pfam PF01098 Cell cycle protein 25 368 5.9E-110 T 13-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_06310 12412370caebb0c69fdc2f02f0e491b5 372 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 325 349 - T 13-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_10880 0d3d5afa2aa9f4b5ce99799473865758 289 Gene3D G3DSA:2.60.120.10 17 280 6.9E-81 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_10880 0d3d5afa2aa9f4b5ce99799473865758 289 PIRSF PIRSF006232 2 289 1.7E-85 T 13-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 THITH_10880 0d3d5afa2aa9f4b5ce99799473865758 289 SUPERFAMILY SSF51182 2 288 8.26E-78 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily THITH_10880 0d3d5afa2aa9f4b5ce99799473865758 289 Pfam PF05726 Pirin C-terminal cupin domain 183 285 2.2E-26 T 13-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 THITH_10880 0d3d5afa2aa9f4b5ce99799473865758 289 Pfam PF02678 Pirin 20 127 2.4E-33 T 13-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 THITH_10880 0d3d5afa2aa9f4b5ce99799473865758 289 Gene3D G3DSA:2.60.120.10 149 254 6.9E-81 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_12455 7548fd9a371b4df71a1409822d800651 153 Pfam PF16998 17 kDa outer membrane surface antigen 48 151 3.8E-7 T 13-10-2018 IPR032635 Surface antigen domain THITH_12455 7548fd9a371b4df71a1409822d800651 153 PIRSF PIRSF002721 4 153 1.2E-39 T 13-10-2018 IPR016364 Surface antigen, Rickettsia type THITH_00785 c0cc3b2aa8aa3e780d519ce5419cbe4d 590 Pfam PF02652 L-lactate permease 7 551 1.0E-113 T 13-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 THITH_00785 c0cc3b2aa8aa3e780d519ce5419cbe4d 590 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 7 556 1.8E-112 T 13-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 THITH_03310 0f4d61e3586a45ff4ab49aefe1d4171a 903 SUPERFAMILY SSF48208 430 899 4.9E-40 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 THITH_05780 f1c118f0ad4963d16dc5bab7981e54c1 472 Pfam PF13440 Polysaccharide biosynthesis protein 32 327 1.5E-30 T 13-10-2018 THITH_06705 31b36bb9ec55b52d94ff625bfeb704f3 265 Pfam PF02237 Biotin protein ligase C terminal domain 217 260 6.3E-5 T 13-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THITH_06705 31b36bb9ec55b52d94ff625bfeb704f3 265 SUPERFAMILY SSF55681 21 212 3.98E-36 T 13-10-2018 THITH_06705 31b36bb9ec55b52d94ff625bfeb704f3 265 Pfam PF03099 Biotin/lipoate A/B protein ligase family 27 152 4.1E-11 T 13-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 THITH_06705 31b36bb9ec55b52d94ff625bfeb704f3 265 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 22 259 3.8E-41 T 13-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 THITH_06705 31b36bb9ec55b52d94ff625bfeb704f3 265 Gene3D G3DSA:2.30.30.100 216 263 2.6E-5 T 13-10-2018 THITH_06705 31b36bb9ec55b52d94ff625bfeb704f3 265 Gene3D G3DSA:3.30.930.10 12 214 2.8E-45 T 13-10-2018 THITH_17060 5ed14d13023d2341259435488e31d632 178 TIGRFAM TIGR01383 not_thiJ: DJ-1 family protein 2 174 1.5E-50 T 13-10-2018 IPR006287 Protein/nucleic acid deglycase DJ-1 Reactome: R-HSA-3899300 THITH_17060 5ed14d13023d2341259435488e31d632 178 Pfam PF01965 DJ-1/PfpI family 2 161 2.5E-45 T 13-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 THITH_17060 5ed14d13023d2341259435488e31d632 178 Gene3D G3DSA:3.40.50.880 1 178 4.8E-53 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_17060 5ed14d13023d2341259435488e31d632 178 SUPERFAMILY SSF52317 2 174 1.44E-51 T 13-10-2018 IPR029062 Class I glutamine amidotransferase-like THITH_11885 ad31eeeaa0968eb121df3abf4e09adc3 386 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 13-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 THITH_11885 ad31eeeaa0968eb121df3abf4e09adc3 386 Pfam PF00155 Aminotransferase class I and II 31 379 1.6E-59 T 13-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 THITH_11885 ad31eeeaa0968eb121df3abf4e09adc3 386 SUPERFAMILY SSF53383 2 385 5.24E-105 T 13-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase THITH_11885 ad31eeeaa0968eb121df3abf4e09adc3 386 Gene3D G3DSA:3.40.640.10 4 386 1.1E-123 T 13-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 THITH_13995 377fa4ea5aa835e8921ed1517f6e23ce 570 Gene3D G3DSA:3.40.50.620 291 569 1.4E-109 T 13-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold THITH_13995 377fa4ea5aa835e8921ed1517f6e23ce 570 Hamap MF_02090 Glutamine-dependent NAD(+) synthetase [nadE]. 7 569 28.878 T 13-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 THITH_13995 377fa4ea5aa835e8921ed1517f6e23ce 570 SUPERFAMILY SSF56317 6 244 9.81E-65 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily THITH_13995 377fa4ea5aa835e8921ed1517f6e23ce 570 Gene3D G3DSA:3.60.110.10 2 250 3.4E-89 T 13-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily THITH_13995 377fa4ea5aa835e8921ed1517f6e23ce 570 Pfam PF00795 Carbon-nitrogen hydrolase 8 243 1.8E-33 T 13-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 THITH_13995 377fa4ea5aa835e8921ed1517f6e23ce 570 PIRSF PIRSF006630 4 570 4.0E-188 T 13-10-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 THITH_13995 377fa4ea5aa835e8921ed1517f6e23ce 570 SUPERFAMILY SSF52402 286 551 4.19E-73 T 13-10-2018 THITH_13995 377fa4ea5aa835e8921ed1517f6e23ce 570 Pfam PF02540 NAD synthase 293 544 6.7E-72 T 13-10-2018 IPR022310 NAD/GMP synthase THITH_13995 377fa4ea5aa835e8921ed1517f6e23ce 570 TIGRFAM TIGR00552 nadE: NAD+ synthetase 300 546 6.8E-59 T 13-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 THITH_13995 377fa4ea5aa835e8921ed1517f6e23ce 570 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 39 54 - T 13-10-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 THITH_16805 49923375612c29182040d275040d6f2d 420 Pfam PF12704 MacB-like periplasmic core domain 20 206 9.7E-11 T 13-10-2018 IPR025857 MacB-like periplasmic core domain THITH_16805 49923375612c29182040d275040d6f2d 420 Pfam PF02687 FtsX-like permease family 318 409 2.4E-10 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THITH_03340 5017771156b34d580206fc58c357f7f6 122 Gene3D G3DSA:2.60.120.10 9 119 2.8E-18 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_03340 5017771156b34d580206fc58c357f7f6 122 Pfam PF07883 Cupin domain 36 105 7.3E-10 T 13-10-2018 IPR013096 Cupin 2, conserved barrel THITH_03340 5017771156b34d580206fc58c357f7f6 122 SUPERFAMILY SSF51182 15 110 8.92E-22 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily THITH_10060 a73f04ac5b89a0d097f36e4da9ae1483 580 Pfam PF03065 Glycosyl hydrolase family 57 24 483 2.4E-68 T 13-10-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 THITH_10060 a73f04ac5b89a0d097f36e4da9ae1483 580 Gene3D G3DSA:3.20.110.20 204 501 1.4E-15 T 13-10-2018 THITH_10060 a73f04ac5b89a0d097f36e4da9ae1483 580 SUPERFAMILY SSF88713 20 470 8.01E-85 T 13-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 THITH_10290 4d32322500ab962524c1d64f9f43ee04 114 SUPERFAMILY SSF52091 36 107 4.32E-6 T 13-10-2018 IPR036513 STAS domain superfamily THITH_10290 4d32322500ab962524c1d64f9f43ee04 114 Gene3D G3DSA:3.30.750.24 10 109 1.9E-6 T 13-10-2018 IPR036513 STAS domain superfamily THITH_10195 3f0414c346ccb93457af95a78e45194b 166 Pfam PF07963 Prokaryotic N-terminal methylation motif 20 40 6.6E-7 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_10195 3f0414c346ccb93457af95a78e45194b 166 SUPERFAMILY SSF54523 22 145 2.59E-9 T 13-10-2018 THITH_10195 3f0414c346ccb93457af95a78e45194b 166 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 20 40 6.1E-7 T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_10195 3f0414c346ccb93457af95a78e45194b 166 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 20 40 - T 13-10-2018 IPR012902 Prokaryotic N-terminal methylation site THITH_10195 3f0414c346ccb93457af95a78e45194b 166 Pfam PF12019 Type II transport protein GspH 63 152 7.5E-7 T 13-10-2018 IPR022346 General secretion pathway, GspH GO:0008565|GO:0015627|GO:0015628 THITH_09035 7e18a437d94ddb84b9a123ac7f04c59a 260 Pfam PF01061 ABC-2 type transporter 12 222 8.9E-34 T 13-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 THITH_09035 7e18a437d94ddb84b9a123ac7f04c59a 260 PRINTS PR00164 ABC-2 type transport system membrane protein signature 180 199 1.6E-9 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 THITH_09035 7e18a437d94ddb84b9a123ac7f04c59a 260 PRINTS PR00164 ABC-2 type transport system membrane protein signature 143 167 1.6E-9 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 THITH_09035 7e18a437d94ddb84b9a123ac7f04c59a 260 PRINTS PR00164 ABC-2 type transport system membrane protein signature 200 219 1.6E-9 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 THITH_09035 7e18a437d94ddb84b9a123ac7f04c59a 260 PRINTS PR00164 ABC-2 type transport system membrane protein signature 62 84 1.6E-9 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 THITH_09035 7e18a437d94ddb84b9a123ac7f04c59a 260 PIRSF PIRSF006648 2 257 2.1E-22 T 13-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 THITH_08730 9080ca9368c14858f276e6e7d556ce32 435 SUPERFAMILY SSF56322 13 433 5.23E-125 T 13-10-2018 IPR005801 ADC synthase GO:0009058 THITH_08730 9080ca9368c14858f276e6e7d556ce32 435 Gene3D G3DSA:3.60.120.10 1 435 4.5E-149 T 13-10-2018 IPR005801 ADC synthase GO:0009058 THITH_08730 9080ca9368c14858f276e6e7d556ce32 435 PRINTS PR00095 Anthranilate synthase component I signature 367 381 1.8E-18 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THITH_08730 9080ca9368c14858f276e6e7d556ce32 435 PRINTS PR00095 Anthranilate synthase component I signature 382 396 1.8E-18 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THITH_08730 9080ca9368c14858f276e6e7d556ce32 435 PRINTS PR00095 Anthranilate synthase component I signature 286 299 1.8E-18 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THITH_08730 9080ca9368c14858f276e6e7d556ce32 435 PRINTS PR00095 Anthranilate synthase component I signature 272 285 1.8E-18 T 13-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 THITH_08730 9080ca9368c14858f276e6e7d556ce32 435 Pfam PF00425 chorismate binding enzyme 169 425 2.7E-95 T 13-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal THITH_05505 520430c7218e734fed6c8721a16f3bf3 162 Pfam PF02639 Uncharacterized BCR, YaiI/YqxD family COG1671 17 145 2.6E-49 T 13-10-2018 IPR003791 Protein of unknown function UPF0178 THITH_05505 520430c7218e734fed6c8721a16f3bf3 162 Hamap MF_00489 UPF0178 protein YaiI [yaiI]. 1 147 31.731 T 13-10-2018 IPR003791 Protein of unknown function UPF0178 THITH_09525 045029979638882c6f11a5d467c3bfe8 145 Pfam PF06146 Phosphate-starvation-inducible E 46 112 1.9E-18 T 13-10-2018 IPR020948 Phosphate-starvation-induced PsiE-like THITH_09525 045029979638882c6f11a5d467c3bfe8 145 PIRSF PIRSF029598 2 130 9.6E-31 T 13-10-2018 IPR009315 Phosphate-starvation-induced PsiE GO:0016021|GO:0016036 THITH_01505 78cf3b7e6dc19d850c8c80d688762a4c 743 Pfam PF05170 AsmA family 7 607 2.6E-62 T 13-10-2018 IPR007844 AsmA THITH_01425 44159be62af4dc2424ee4597b2d636eb 170 SUPERFAMILY SSF54534 6 141 3.93E-16 T 13-10-2018 THITH_01425 44159be62af4dc2424ee4597b2d636eb 170 Gene3D G3DSA:2.40.10.330 74 124 2.2E-31 T 13-10-2018 THITH_01425 44159be62af4dc2424ee4597b2d636eb 170 Gene3D G3DSA:3.10.50.40 6 153 2.2E-31 T 13-10-2018 THITH_14540 7f6c5dabe23b98c0b718c9c39972b33d 142 SUPERFAMILY SSF101738 1 111 4.58E-44 T 13-10-2018 IPR036760 SspB-like superfamily THITH_14540 7f6c5dabe23b98c0b718c9c39972b33d 142 PIRSF PIRSF005276 1 142 2.7E-52 T 13-10-2018 IPR007481 Stringent starvation protein B THITH_14540 7f6c5dabe23b98c0b718c9c39972b33d 142 Gene3D G3DSA:2.30.30.220 1 124 1.5E-47 T 13-10-2018 IPR036760 SspB-like superfamily THITH_14540 7f6c5dabe23b98c0b718c9c39972b33d 142 Pfam PF04386 Stringent starvation protein B 4 142 1.9E-33 T 13-10-2018 IPR007481 Stringent starvation protein B THITH_12300 54accf6ca8edc862f13481cb2bc38e00 195 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 33 131 1.3E-10 T 13-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain THITH_12300 54accf6ca8edc862f13481cb2bc38e00 195 SUPERFAMILY SSF53927 8 186 7.53E-31 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 THITH_12300 54accf6ca8edc862f13481cb2bc38e00 195 Gene3D G3DSA:3.40.140.10 12 181 5.5E-32 T 13-10-2018 THITH_12300 54accf6ca8edc862f13481cb2bc38e00 195 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 81 120 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 THITH_05815 6ff03aa3f32c8eef303d763f4c215b80 399 Gene3D G3DSA:3.40.50.20 49 103 9.9E-16 T 13-10-2018 THITH_05815 6ff03aa3f32c8eef303d763f4c215b80 399 Gene3D G3DSA:3.30.470.20 201 299 9.9E-16 T 13-10-2018 THITH_05815 6ff03aa3f32c8eef303d763f4c215b80 399 SUPERFAMILY SSF56059 113 306 4.65E-22 T 13-10-2018 THITH_05815 6ff03aa3f32c8eef303d763f4c215b80 399 Gene3D G3DSA:3.30.1490.20 104 200 9.9E-16 T 13-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 THITH_07770 3012fd0fc96fc6840e7eb00f9dbe4c84 175 Gene3D G3DSA:2.60.120.10 43 163 3.9E-21 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_07770 3012fd0fc96fc6840e7eb00f9dbe4c84 175 SUPERFAMILY SSF51182 60 152 2.58E-20 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily THITH_07770 3012fd0fc96fc6840e7eb00f9dbe4c84 175 Pfam PF12973 ChrR Cupin-like domain 62 149 2.5E-14 T 13-10-2018 IPR025979 ChrR-like cupin domain THITH_04685 0b99051967e62709cfb44456b6ccaa0e 178 Pfam PF08463 EcoEI R protein C-terminal 78 165 1.5E-10 T 13-10-2018 IPR013670 EcoEI R protein C-terminal domain GO:0003677|GO:0003824|GO:0006304 THITH_16600 8c388187a6b45835527bc6a61626a42d 297 Pfam PF04116 Fatty acid hydroxylase superfamily 92 228 1.3E-25 T 13-10-2018 IPR006694 Fatty acid hydroxylase GO:0005506|GO:0008610|GO:0016491|GO:0055114 THITH_02865 e8fe3703772c4f4e5bd3853061d6f9d9 96 SMART SM00834 1 42 3.1E-19 T 13-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain THITH_02865 e8fe3703772c4f4e5bd3853061d6f9d9 96 Pfam PF09723 Zinc ribbon domain 1 41 5.7E-17 T 13-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain THITH_02865 e8fe3703772c4f4e5bd3853061d6f9d9 96 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 1 52 2.5E-22 T 13-10-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain THITH_12510 fa475396501ce519cd0f7dbf30584679 812 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 192 544 18.306 T 13-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 THITH_12510 fa475396501ce519cd0f7dbf30584679 812 Pfam PF01564 Spermine/spermidine synthase domain 297 451 1.2E-21 T 13-10-2018 THITH_12510 fa475396501ce519cd0f7dbf30584679 812 SUPERFAMILY SSF53335 237 488 3.18E-39 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_12510 fa475396501ce519cd0f7dbf30584679 812 SUPERFAMILY SSF103473 594 807 6.02E-7 T 13-10-2018 IPR036259 MFS transporter superfamily THITH_12510 fa475396501ce519cd0f7dbf30584679 812 Gene3D G3DSA:3.40.50.150 291 508 1.0E-48 T 13-10-2018 THITH_03680 2599ce78889e6601e20386ce69e91506 131 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 121 9.8E-10 T 13-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain THITH_03680 2599ce78889e6601e20386ce69e91506 131 SUPERFAMILY SSF54593 2 126 5.5E-25 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THITH_03680 2599ce78889e6601e20386ce69e91506 131 Gene3D G3DSA:3.10.180.10 1 127 1.8E-23 T 13-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase THITH_16760 6f9c3ce0de56aa57bf3f43b424a340c3 320 Pfam PF01758 Sodium Bile acid symporter family 42 217 4.7E-19 T 13-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 THITH_16760 6f9c3ce0de56aa57bf3f43b424a340c3 320 Gene3D G3DSA:1.20.1530.20 3 315 2.7E-28 T 13-10-2018 IPR038770 Sodium/solute symporter superfamily THITH_02595 c7394ab4f294435d01de938660358788 380 Pfam PF06804 NlpB/DapX lipoprotein 38 315 1.6E-28 T 13-10-2018 IPR010653 NlpB/DapX lipoprotein THITH_03240 e9bd93079a43cccec2adffbfa139882f 345 Gene3D G3DSA:3.40.190.10 36 330 7.3E-20 T 13-10-2018 THITH_03240 e9bd93079a43cccec2adffbfa139882f 345 Gene3D G3DSA:3.40.190.10 123 261 7.3E-20 T 13-10-2018 THITH_03240 e9bd93079a43cccec2adffbfa139882f 345 SUPERFAMILY SSF53850 31 334 2.93E-19 T 13-10-2018 THITH_13780 f850363e46bd800f0b5f04019abf736b 427 TIGRFAM TIGR02564 cas_Csy1: CRISPR type I-F/YPEST-associated protein Csy1 40 421 5.9E-112 T 13-10-2018 IPR013397 CRISPR-associated protein Csy1 THITH_13780 f850363e46bd800f0b5f04019abf736b 427 Pfam PF09611 CRISPR-associated protein (Cas_Csy1) 41 417 3.4E-136 T 13-10-2018 IPR013397 CRISPR-associated protein Csy1 THITH_08015 68b2c83c324ed187b2c61f79e66a25fb 269 SUPERFAMILY SSF53335 20 199 7.1E-12 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_08015 68b2c83c324ed187b2c61f79e66a25fb 269 Gene3D G3DSA:3.40.50.150 23 256 2.6E-8 T 13-10-2018 THITH_16770 b6f2575b501a940dc733791035211023 85 Gene3D G3DSA:1.10.1220.10 3 52 1.8E-17 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THITH_16770 b6f2575b501a940dc733791035211023 85 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 1 83 2.6E-23 T 13-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ THITH_16770 b6f2575b501a940dc733791035211023 85 PIRSF PIRSF003108 1 85 1.2E-29 T 13-10-2018 IPR026262 Antitoxin DinJ GO:0000986|GO:0015643|GO:0044010 THITH_16770 b6f2575b501a940dc733791035211023 85 Pfam PF04221 RelB antitoxin 6 79 2.0E-21 T 13-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ THITH_05140 30da33087c812cd1ee3365824079d2b6 73 TIGRFAM TIGR02574 stabl_TIGR02574: putative addiction module component, TIGR02574 family 9 71 5.0E-9 T 13-10-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module THITH_05140 30da33087c812cd1ee3365824079d2b6 73 Pfam PF09720 Putative addiction module component 12 64 1.1E-16 T 13-10-2018 IPR013406 Conserved hypothetical protein CHP02574, addiction module THITH_07445 12db6478cf4ac9f1a21ba4addd3a742e 220 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 205 4.8E-48 T 13-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 THITH_07445 12db6478cf4ac9f1a21ba4addd3a742e 220 Gene3D G3DSA:1.10.1760.20 1 211 1.2E-53 T 13-10-2018 THITH_16395 a2f524e2f7dc1302c00696dca199d679 295 SUPERFAMILY SSF56112 9 287 5.1E-38 T 13-10-2018 IPR011009 Protein kinase-like domain superfamily THITH_16395 a2f524e2f7dc1302c00696dca199d679 295 Gene3D G3DSA:3.30.200.20 5 97 8.0E-12 T 13-10-2018 THITH_16395 a2f524e2f7dc1302c00696dca199d679 295 Pfam PF03881 Fructosamine kinase 6 291 5.3E-90 T 13-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 THITH_16395 a2f524e2f7dc1302c00696dca199d679 295 Gene3D G3DSA:3.90.1200.10 103 294 6.2E-61 T 13-10-2018 THITH_16395 a2f524e2f7dc1302c00696dca199d679 295 PIRSF PIRSF006221 4 295 3.4E-79 T 13-10-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 THITH_04875 f3980ad224c9107e54dd4575a841ed65 211 SUPERFAMILY SSF52540 4 208 6.73E-32 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_04875 f3980ad224c9107e54dd4575a841ed65 211 Gene3D G3DSA:3.40.50.300 2 207 1.0E-39 T 13-10-2018 THITH_04875 f3980ad224c9107e54dd4575a841ed65 211 PIRSF PIRSF009320 1 211 1.9E-30 T 13-10-2018 THITH_04875 f3980ad224c9107e54dd4575a841ed65 211 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 113 8.0E-11 T 13-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain THITH_12935 7b6334203f220e2019c93605aa335f50 666 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 65 122 7.4E-28 T 13-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12935 7b6334203f220e2019c93605aa335f50 666 Pfam PF00361 Proton-conducting membrane transporter 134 415 3.5E-84 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12935 7b6334203f220e2019c93605aa335f50 666 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 83 108 1.2E-64 T 13-10-2018 THITH_12935 7b6334203f220e2019c93605aa335f50 666 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 158 179 1.2E-64 T 13-10-2018 THITH_12935 7b6334203f220e2019c93605aa335f50 666 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 111 131 1.2E-64 T 13-10-2018 THITH_12935 7b6334203f220e2019c93605aa335f50 666 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 234 255 1.2E-64 T 13-10-2018 THITH_12935 7b6334203f220e2019c93605aa335f50 666 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 256 282 1.2E-64 T 13-10-2018 THITH_12935 7b6334203f220e2019c93605aa335f50 666 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 324 336 1.2E-64 T 13-10-2018 THITH_12935 7b6334203f220e2019c93605aa335f50 666 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 429 448 1.2E-64 T 13-10-2018 THITH_12935 7b6334203f220e2019c93605aa335f50 666 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 4 664 3.6E-240 T 13-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_07800 fdf9027373bc20abc58853f10fa6f18b 235 Gene3D G3DSA:1.10.10.10 5 123 1.9E-26 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_07800 fdf9027373bc20abc58853f10fa6f18b 235 SUPERFAMILY SSF55718 113 213 5.0E-5 T 13-10-2018 IPR036527 SCP2 sterol-binding domain superfamily THITH_07800 fdf9027373bc20abc58853f10fa6f18b 235 SUPERFAMILY SSF46785 7 104 1.25E-21 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_07800 fdf9027373bc20abc58853f10fa6f18b 235 Pfam PF01638 HxlR-like helix-turn-helix 19 101 2.5E-17 T 13-10-2018 IPR002577 Helix-turn-helix, HxlR type THITH_13315 23593774e04d7ee92472e8f5db66c788 222 SUPERFAMILY SSF52540 1 219 3.34E-63 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_13315 23593774e04d7ee92472e8f5db66c788 222 SMART SM00382 30 218 1.4E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_13315 23593774e04d7ee92472e8f5db66c788 222 Gene3D G3DSA:3.40.50.300 1 222 6.4E-65 T 13-10-2018 THITH_13315 23593774e04d7ee92472e8f5db66c788 222 Pfam PF00005 ABC transporter 21 168 6.1E-35 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_13315 23593774e04d7ee92472e8f5db66c788 222 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_04225 2195db09f733dc154add6552fed2c60d 506 Pfam PF04932 O-Antigen ligase 197 426 5.7E-9 T 13-10-2018 IPR007016 O-antigen ligase-related THITH_05740 2d6e800e2d1f174c4a679d031cc95ac4 100 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 40 2.5E-13 T 13-10-2018 THITH_05740 2d6e800e2d1f174c4a679d031cc95ac4 100 TIGRFAM TIGR04176 MarR_EPS: EPS-associated transcriptional regulator, MarR family 1 95 7.5E-44 T 13-10-2018 IPR026433 EPS-associated transcriptional regulator, MarR family THITH_05740 2d6e800e2d1f174c4a679d031cc95ac4 100 Gene3D G3DSA:1.10.10.10 1 98 2.8E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_05740 2d6e800e2d1f174c4a679d031cc95ac4 100 SUPERFAMILY SSF46785 2 94 1.06E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_02150 08d4c0a729baa09bf8d62c64693e1001 403 SUPERFAMILY SSF50952 38 399 1.09E-29 T 13-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 THITH_02150 08d4c0a729baa09bf8d62c64693e1001 403 Pfam PF07995 Glucose / Sorbosone dehydrogenase 50 395 4.1E-103 T 13-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase THITH_02150 08d4c0a729baa09bf8d62c64693e1001 403 Gene3D G3DSA:2.120.10.30 36 399 8.9E-97 T 13-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like THITH_05320 f7d949de9c01e9c372560e3308152e14 240 SUPERFAMILY SSF52540 8 230 1.46E-64 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_05320 f7d949de9c01e9c372560e3308152e14 240 Gene3D G3DSA:3.40.50.300 6 237 1.2E-67 T 13-10-2018 THITH_05320 f7d949de9c01e9c372560e3308152e14 240 ProSitePatterns PS00211 ABC transporters family signature. 150 164 - T 13-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 THITH_05320 f7d949de9c01e9c372560e3308152e14 240 Pfam PF00005 ABC transporter 28 177 1.9E-34 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_05320 f7d949de9c01e9c372560e3308152e14 240 SMART SM00382 37 226 2.3E-18 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_00770 b9b2272c2631cf5996fbddd813a63846 271 Pfam PF02754 Cysteine-rich domain 20 100 8.1E-13 T 13-10-2018 IPR004017 Cysteine-rich domain THITH_00770 b9b2272c2631cf5996fbddd813a63846 271 Pfam PF02754 Cysteine-rich domain 148 231 1.0E-12 T 13-10-2018 IPR004017 Cysteine-rich domain THITH_05900 bac6f66eeb3a8c4e56cbafa1c6729dca 171 Gene3D G3DSA:3.40.630.30 3 161 4.9E-34 T 13-10-2018 THITH_05900 bac6f66eeb3a8c4e56cbafa1c6729dca 171 SUPERFAMILY SSF55729 45 157 1.19E-8 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_05900 bac6f66eeb3a8c4e56cbafa1c6729dca 171 Pfam PF00583 Acetyltransferase (GNAT) family 84 145 1.9E-4 T 13-10-2018 IPR000182 GNAT domain THITH_15785 ff215063d5cc86fe46827a9a55c54da7 343 SUPERFAMILY SSF53187 24 277 1.32E-37 T 13-10-2018 THITH_15785 ff215063d5cc86fe46827a9a55c54da7 343 Pfam PF04952 Succinylglutamate desuccinylase / Aspartoacylase family 50 211 5.9E-11 T 13-10-2018 IPR007036 Succinylglutamate desuccinylase/aspartoacylase GO:0016788 THITH_15785 ff215063d5cc86fe46827a9a55c54da7 343 Gene3D G3DSA:3.40.630.10 10 287 5.1E-26 T 13-10-2018 THITH_16520 e46c42f47fa850c16451acd651025474 244 TIGRFAM TIGR00781 ccoO: cytochrome c oxidase, cbb3-type, subunit II 4 236 8.6E-98 T 13-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO THITH_16520 e46c42f47fa850c16451acd651025474 244 Pfam PF02433 Cytochrome C oxidase, mono-heme subunit/FixO 3 230 4.4E-94 T 13-10-2018 IPR003468 Cytochrome c oxidase, monohaem subunit/FixO THITH_16520 e46c42f47fa850c16451acd651025474 244 SUPERFAMILY SSF46626 14 224 6.9E-26 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_15160 83c4c6dd97e3519b27d17c932f8c0188 128 Pfam PF00072 Response regulator receiver domain 1 113 7.7E-13 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_15160 83c4c6dd97e3519b27d17c932f8c0188 128 Gene3D G3DSA:3.40.50.2300 1 127 1.4E-17 T 13-10-2018 THITH_15160 83c4c6dd97e3519b27d17c932f8c0188 128 SMART SM00448 1 114 0.0027 T 13-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 THITH_15160 83c4c6dd97e3519b27d17c932f8c0188 128 SUPERFAMILY SSF52172 1 118 2.42E-16 T 13-10-2018 IPR011006 CheY-like superfamily THITH_16550 6aedb45b6feb569a4472ddac7ca346cf 404 Gene3D G3DSA:3.40.50.12710 16 404 1.5E-108 T 13-10-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 THITH_16550 6aedb45b6feb569a4472ddac7ca346cf 404 SUPERFAMILY SSF53335 34 390 3.04E-83 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_16550 6aedb45b6feb569a4472ddac7ca346cf 404 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 100 329 2.9E-46 T 13-10-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 THITH_05715 166dc314c3b81832887c9aab935445dc 89 Gene3D G3DSA:3.10.450.530 1 83 6.0E-13 T 13-10-2018 IPR038573 Ribonuclease toxin BrnT superfamily THITH_05715 166dc314c3b81832887c9aab935445dc 89 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 5 81 2.5E-21 T 13-10-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system THITH_14135 049fcd8c2b243a20ec4093c607b909ff 324 Gene3D G3DSA:3.40.50.300 106 312 3.6E-68 T 13-10-2018 THITH_14135 049fcd8c2b243a20ec4093c607b909ff 324 SUPERFAMILY SSF52540 110 284 1.31E-34 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_14135 049fcd8c2b243a20ec4093c607b909ff 324 Pfam PF02562 PhoH-like protein 109 312 7.5E-90 T 13-10-2018 IPR003714 PhoH-like protein GO:0005524 THITH_13370 c4acb2469c0d6bfcdd483dc0d682810d 150 Pfam PF16998 17 kDa outer membrane surface antigen 68 147 1.2E-7 T 13-10-2018 IPR032635 Surface antigen domain THITH_13370 c4acb2469c0d6bfcdd483dc0d682810d 150 PIRSF PIRSF002721 1 150 1.4E-35 T 13-10-2018 IPR016364 Surface antigen, Rickettsia type THITH_01225 bab4b6ed868e8c630ae445e9d3c081a9 135 Pfam PF07635 Planctomycete cytochrome C 51 110 6.0E-7 T 13-10-2018 IPR011429 Cytochrome C, Planctomycete-type THITH_01225 bab4b6ed868e8c630ae445e9d3c081a9 135 SUPERFAMILY SSF46626 41 132 1.16E-6 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_06540 70dd07376eb42532ecafbfcae17ddf51 97 Pfam PF11839 Alanine-zipper, major outer membrane lipoprotein 30 97 4.8E-14 T 13-10-2018 IPR021793 Major outer membrane lipoprotein Oprl THITH_05645 27f0b759d2f299dc49c61829b5f426ce 100 TIGRFAM TIGR04176 MarR_EPS: EPS-associated transcriptional regulator, MarR family 1 95 2.2E-43 T 13-10-2018 IPR026433 EPS-associated transcriptional regulator, MarR family THITH_05645 27f0b759d2f299dc49c61829b5f426ce 100 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 40 8.6E-14 T 13-10-2018 THITH_05645 27f0b759d2f299dc49c61829b5f426ce 100 SUPERFAMILY SSF46785 2 93 1.13E-14 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_05645 27f0b759d2f299dc49c61829b5f426ce 100 Gene3D G3DSA:1.10.10.10 1 98 4.1E-15 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_03685 77fbc1130e8c224861366bcd3357521f 220 SUPERFAMILY SSF46689 150 199 5.38E-9 T 13-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 THITH_03685 77fbc1130e8c224861366bcd3357521f 220 SMART SM00342 113 195 4.0E-10 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THITH_03685 77fbc1130e8c224861366bcd3357521f 220 Gene3D G3DSA:1.10.10.60 101 200 8.3E-17 T 13-10-2018 THITH_03685 77fbc1130e8c224861366bcd3357521f 220 Pfam PF12833 Helix-turn-helix domain 120 197 6.0E-15 T 13-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 THITH_10740 78f03b3bd91fb9362a939dc8bef203fa 196 Pfam PF05036 Sporulation related domain 120 193 5.2E-15 T 13-10-2018 IPR007730 Sporulation-like domain GO:0042834 THITH_10740 78f03b3bd91fb9362a939dc8bef203fa 196 Gene3D G3DSA:3.30.70.1070 121 194 2.0E-12 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 THITH_10740 78f03b3bd91fb9362a939dc8bef203fa 196 SUPERFAMILY SSF110997 120 193 1.7E-15 T 13-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 THITH_13565 4de7dc149da496a08e71ec1f291f8f79 143 Pfam PF00472 RF-1 domain 8 133 3.7E-24 T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THITH_13565 4de7dc149da496a08e71ec1f291f8f79 143 Gene3D G3DSA:3.30.160.20 1 138 1.5E-40 T 13-10-2018 THITH_13565 4de7dc149da496a08e71ec1f291f8f79 143 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 21 37 - T 13-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 THITH_13565 4de7dc149da496a08e71ec1f291f8f79 143 SUPERFAMILY SSF75620 7 101 4.32E-14 T 13-10-2018 THITH_15870 90f69b537e56a23bc59cdf7ad6a4f95a 271 Pfam PF07819 PGAP1-like protein 102 154 4.8E-8 T 13-10-2018 IPR012908 GPI inositol-deacylase PGAP1-like GO:0016788 Reactome: R-HSA-162791 THITH_15870 90f69b537e56a23bc59cdf7ad6a4f95a 271 SUPERFAMILY SSF53474 88 230 1.98E-13 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_12140 538851d872e2735e1d16c4e0bc3d6fff 125 Pfam PF16137 Domain of unknown function (DUF4845) 37 117 5.5E-21 T 13-10-2018 IPR032314 Protein of unknown function DUF4845 THITH_00515 ed9c3b8c1418364def555cd0f9bec357 233 Gene3D G3DSA:3.30.450.40 48 228 5.1E-45 T 13-10-2018 IPR029016 GAF-like domain superfamily THITH_00515 ed9c3b8c1418364def555cd0f9bec357 233 SUPERFAMILY SSF55781 82 215 2.45E-7 T 13-10-2018 THITH_00515 ed9c3b8c1418364def555cd0f9bec357 233 Pfam PF04340 Protein of unknown function, DUF484 15 222 9.9E-46 T 13-10-2018 IPR007435 Protein of unknown function DUF484 THITH_08300 e2ee055b17b441a730ffc7cefe3e02e9 198 Pfam PF05685 Putative restriction endonuclease 13 173 1.6E-26 T 13-10-2018 IPR008538 Domain of unknown function DUF820 THITH_08300 e2ee055b17b441a730ffc7cefe3e02e9 198 Gene3D G3DSA:3.90.1570.10 3 153 3.7E-15 T 13-10-2018 THITH_08300 e2ee055b17b441a730ffc7cefe3e02e9 198 SUPERFAMILY SSF52980 6 180 9.65E-22 T 13-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 THITH_13170 cbfbc7adf4fdd5aef09291d2c06d25f8 452 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 32 46 - T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 THITH_13170 cbfbc7adf4fdd5aef09291d2c06d25f8 452 Pfam PF00209 Sodium:neurotransmitter symporter family 155 448 1.5E-23 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 THITH_13170 cbfbc7adf4fdd5aef09291d2c06d25f8 452 Pfam PF00209 Sodium:neurotransmitter symporter family 9 125 8.0E-27 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 THITH_13170 cbfbc7adf4fdd5aef09291d2c06d25f8 452 SUPERFAMILY SSF161070 9 449 3.14E-132 T 13-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 THITH_13170 cbfbc7adf4fdd5aef09291d2c06d25f8 452 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 45 64 5.0E-14 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 THITH_13170 cbfbc7adf4fdd5aef09291d2c06d25f8 452 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 16 37 5.0E-14 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 THITH_13170 cbfbc7adf4fdd5aef09291d2c06d25f8 452 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 305 324 5.0E-14 T 13-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 THITH_14685 6f5a848d8cb4864ef0fb6dc611c9929d 141 Gene3D G3DSA:3.40.50.510 2 138 1.5E-34 T 13-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 THITH_14685 6f5a848d8cb4864ef0fb6dc611c9929d 141 SUPERFAMILY SSF53062 2 130 1.23E-31 T 13-10-2018 IPR036662 Phosphotransferase system, mannose-type IIA component superfamily GO:0009401|GO:0016021 THITH_14685 6f5a848d8cb4864ef0fb6dc611c9929d 141 Pfam PF03610 PTS system fructose IIA component 4 106 3.1E-19 T 13-10-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 THITH_03395 825d3c2de7c4d37dc6eb25972a2784e0 157 SUPERFAMILY SSF81593 18 125 4.32E-14 T 13-10-2018 THITH_02300 ebfde8829b021f598ea6b996083dbde2 109 Gene3D G3DSA:2.30.30.110 1 108 2.3E-17 T 13-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor THITH_02300 ebfde8829b021f598ea6b996083dbde2 109 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 2 105 1.7E-17 T 13-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 THITH_02300 ebfde8829b021f598ea6b996083dbde2 109 SUPERFAMILY SSF50118 1 108 4.14E-22 T 13-10-2018 THITH_11110 d3ad86a58e40c6f8035463c99fc1ce2b 138 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 6 133 9.645 T 13-10-2018 IPR022907 VapC family GO:0004540 THITH_11110 d3ad86a58e40c6f8035463c99fc1ce2b 138 SUPERFAMILY SSF88723 4 135 6.45E-29 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_11110 d3ad86a58e40c6f8035463c99fc1ce2b 138 Pfam PF01850 PIN domain 8 127 5.9E-12 T 13-10-2018 IPR002716 PIN domain THITH_11110 d3ad86a58e40c6f8035463c99fc1ce2b 138 Gene3D G3DSA:3.40.50.1010 3 135 2.2E-30 T 13-10-2018 THITH_01935 0adc28fd9c072ef35760fc3c06c58f68 96 Gene3D G3DSA:3.30.2310.20 1 96 5.9E-22 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_01935 0adc28fd9c072ef35760fc3c06c58f68 96 Pfam PF05015 RelE-like toxin of type II toxin-antitoxin system HigB 4 96 2.0E-15 T 13-10-2018 IPR007711 Toxin HigB-1 THITH_01935 0adc28fd9c072ef35760fc3c06c58f68 96 SUPERFAMILY SSF143011 3 96 1.96E-14 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_11650 ff64bb6d01467392b106c1b71c3a5042 259 Pfam PF13444 Acetyltransferase (GNAT) domain 36 136 3.1E-31 T 13-10-2018 THITH_11650 ff64bb6d01467392b106c1b71c3a5042 259 Gene3D G3DSA:3.40.630.30 20 162 9.7E-22 T 13-10-2018 THITH_11650 ff64bb6d01467392b106c1b71c3a5042 259 SUPERFAMILY SSF55729 21 227 3.8E-38 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_11975 f91c70d6ae4ee1ea66d3efad81982ce6 307 Gene3D G3DSA:3.60.130.10 24 306 3.3E-30 T 13-10-2018 THITH_11975 f91c70d6ae4ee1ea66d3efad81982ce6 307 SUPERFAMILY SSF51197 22 301 1.19E-38 T 13-10-2018 THITH_11975 f91c70d6ae4ee1ea66d3efad81982ce6 307 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 41 297 6.1E-21 T 13-10-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 THITH_01835 7c8c5ad5e1a102ea7fbed9a6ce1a1313 307 SUPERFAMILY SSF53807 23 305 1.77E-47 T 13-10-2018 THITH_01835 7c8c5ad5e1a102ea7fbed9a6ce1a1313 307 Gene3D G3DSA:3.40.50.1980 202 306 2.7E-5 T 13-10-2018 THITH_01835 7c8c5ad5e1a102ea7fbed9a6ce1a1313 307 Gene3D G3DSA:3.40.50.1980 35 201 4.9E-30 T 13-10-2018 THITH_01835 7c8c5ad5e1a102ea7fbed9a6ce1a1313 307 Pfam PF01297 Zinc-uptake complex component A periplasmic 38 305 2.5E-33 T 13-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 THITH_05445 475e27ade78f3c2a747caf14c848ead3 317 TIGRFAM TIGR04348 TIGR04348: putative glycosyltransferase, TIGR04348 family 3 313 1.1E-135 T 13-10-2018 IPR027627 Putative glycosyltransferase THITH_05445 475e27ade78f3c2a747caf14c848ead3 317 Gene3D G3DSA:3.40.50.2000 132 293 2.7E-17 T 13-10-2018 THITH_05445 475e27ade78f3c2a747caf14c848ead3 317 SUPERFAMILY SSF53756 2 314 4.85E-31 T 13-10-2018 THITH_05445 475e27ade78f3c2a747caf14c848ead3 317 Pfam PF00534 Glycosyl transferases group 1 144 279 1.3E-10 T 13-10-2018 IPR001296 Glycosyl transferase, family 1 THITH_03195 821fcb9438abaf53fc61c1a44f6bdd26 99 Pfam PF01909 Nucleotidyltransferase domain 11 79 4.7E-6 T 13-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 THITH_03195 821fcb9438abaf53fc61c1a44f6bdd26 99 Gene3D G3DSA:3.30.460.10 1 99 6.2E-10 T 13-10-2018 THITH_03195 821fcb9438abaf53fc61c1a44f6bdd26 99 SUPERFAMILY SSF81301 9 86 3.27E-8 T 13-10-2018 THITH_15510 b31134fa3a6c14f669f3fc666c8a4878 192 Gene3D G3DSA:2.40.50.140 122 190 5.7E-7 T 13-10-2018 THITH_15510 b31134fa3a6c14f669f3fc666c8a4878 192 Pfam PF00313 'Cold-shock' DNA-binding domain 130 183 5.2E-5 T 13-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 THITH_15510 b31134fa3a6c14f669f3fc666c8a4878 192 SUPERFAMILY SSF69754 9 117 5.62E-19 T 13-10-2018 IPR036567 Ribosome hibernation promotion factor-like THITH_15510 b31134fa3a6c14f669f3fc666c8a4878 192 Gene3D G3DSA:3.30.160.100 7 115 2.1E-13 T 13-10-2018 IPR036567 Ribosome hibernation promotion factor-like THITH_15510 b31134fa3a6c14f669f3fc666c8a4878 192 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 9 110 4.0E-14 T 13-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 THITH_15510 b31134fa3a6c14f669f3fc666c8a4878 192 SUPERFAMILY SSF50249 122 184 1.13E-6 T 13-10-2018 IPR012340 Nucleic acid-binding, OB-fold THITH_02475 5a0767d58389855e8cfd782029393216 273 Pfam PF04085 rod shape-determining protein MreC 109 252 1.2E-30 T 13-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 THITH_02475 5a0767d58389855e8cfd782029393216 273 PIRSF PIRSF038471 1 267 1.7E-68 T 13-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 THITH_02475 5a0767d58389855e8cfd782029393216 273 Gene3D G3DSA:2.40.10.340 104 250 1.5E-26 T 13-10-2018 THITH_02475 5a0767d58389855e8cfd782029393216 273 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 1 258 1.6E-52 T 13-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 THITH_02475 5a0767d58389855e8cfd782029393216 273 Gene3D G3DSA:2.40.10.350 163 240 1.5E-26 T 13-10-2018 THITH_13845 f4e9a566c2db705c745be50e80fb8844 452 ProSitePatterns PS00194 Thioredoxin family active site. 319 337 - T 13-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 THITH_13845 f4e9a566c2db705c745be50e80fb8844 452 Gene3D G3DSA:3.40.30.10 272 431 1.0E-39 T 13-10-2018 THITH_13845 f4e9a566c2db705c745be50e80fb8844 452 Pfam PF00578 AhpC/TSA family 294 407 8.7E-23 T 13-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 THITH_13845 f4e9a566c2db705c745be50e80fb8844 452 SUPERFAMILY SSF52833 292 431 7.43E-42 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_00850 e12ae7db0771a72b60b77cdbffd82def 409 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 348 357 - T 13-10-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 THITH_00850 e12ae7db0771a72b60b77cdbffd82def 409 SUPERFAMILY SSF48264 3 403 4.32E-57 T 13-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 THITH_00850 e12ae7db0771a72b60b77cdbffd82def 409 Pfam PF00067 Cytochrome P450 282 375 1.3E-16 T 13-10-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 THITH_00850 e12ae7db0771a72b60b77cdbffd82def 409 Gene3D G3DSA:1.10.630.10 2 408 2.1E-77 T 13-10-2018 IPR036396 Cytochrome P450 superfamily GO:0005506|GO:0016705|GO:0020037|GO:0055114 THITH_16630 7610edf5065d6af3fb7153b470a73d57 361 Pfam PF14350 Beta protein 8 351 6.8E-74 T 13-10-2018 IPR025683 Protein beta THITH_04675 70f713df2e90ece0f8855a21b434e9e7 153 Pfam PF03682 Uncharacterised protein family (UPF0158) 9 150 8.9E-7 T 13-10-2018 IPR005361 Uncharacterised protein family UPF0158 THITH_01185 67ba62111789c4002372ab59f110ab78 268 SUPERFAMILY SSF110399 11 251 6.02E-89 T 13-10-2018 THITH_01185 67ba62111789c4002372ab59f110ab78 268 Hamap MF_00443 Thiazole synthase [thiG]. 12 267 43.469 T 13-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 THITH_01185 67ba62111789c4002372ab59f110ab78 268 Pfam PF05690 Thiazole biosynthesis protein ThiG 15 261 4.7E-112 T 13-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 THITH_01185 67ba62111789c4002372ab59f110ab78 268 Gene3D G3DSA:3.20.20.70 3 266 9.0E-121 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_06035 405e9fd235a7ebba42fba4115df506e1 90 Pfam PF03693 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH 7 55 1.3E-6 T 13-10-2018 IPR022789 Antitoxin ParD THITH_06035 405e9fd235a7ebba42fba4115df506e1 90 SUPERFAMILY SSF47598 4 50 1.05E-9 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 THITH_06035 405e9fd235a7ebba42fba4115df506e1 90 Gene3D G3DSA:1.10.8.1250 14 89 1.0E-10 T 13-10-2018 IPR038296 Antitoxin ParD superfamily THITH_06180 882acd8c4cab4c423116a2c24ccbaacf 171 SUPERFAMILY SSF158682 27 161 4.84E-26 T 13-10-2018 IPR029024 TerB-like THITH_06180 882acd8c4cab4c423116a2c24ccbaacf 171 Pfam PF05099 Tellurite resistance protein TerB 28 156 1.6E-30 T 13-10-2018 IPR007791 Co-chaperone DjlA, N-terminal THITH_06180 882acd8c4cab4c423116a2c24ccbaacf 171 Gene3D G3DSA:1.10.3680.10 28 153 1.7E-16 T 13-10-2018 IPR029024 TerB-like THITH_04410 98d83419dc0e5bd453d8f941319494de 188 SUPERFAMILY SSF51283 3 187 1.57E-52 T 13-10-2018 IPR036157 dUTPase-like superfamily THITH_04410 98d83419dc0e5bd453d8f941319494de 188 Gene3D G3DSA:2.70.40.10 1 159 4.1E-52 T 13-10-2018 IPR036157 dUTPase-like superfamily THITH_04410 98d83419dc0e5bd453d8f941319494de 188 Hamap MF_00146 dCTP deaminase [dcd]. 1 188 28.697 T 13-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 THITH_04410 98d83419dc0e5bd453d8f941319494de 188 Pfam PF00692 dUTPase 74 184 3.4E-8 T 13-10-2018 IPR029054 dUTPase-like THITH_04410 98d83419dc0e5bd453d8f941319494de 188 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 6 187 2.2E-49 T 13-10-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 THITH_05830 ce6ecb131d3e05f8561a298e8e62765e 385 Pfam PF13173 AAA domain 18 133 1.6E-20 T 13-10-2018 THITH_05830 ce6ecb131d3e05f8561a298e8e62765e 385 SUPERFAMILY SSF52540 16 139 1.33E-8 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_05830 ce6ecb131d3e05f8561a298e8e62765e 385 Pfam PF13635 Domain of unknown function (DUF4143) 175 334 4.4E-30 T 13-10-2018 IPR025420 Domain of unknown function DUF4143 THITH_13400 49218ce2c8e4241f8c1796fc15d8d735 276 Gene3D G3DSA:1.10.4080.10 1 233 1.8E-49 T 13-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily THITH_13400 49218ce2c8e4241f8c1796fc15d8d735 276 Pfam PF03747 ADP-ribosylglycohydrolase 1 224 6.1E-34 T 13-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 THITH_13400 49218ce2c8e4241f8c1796fc15d8d735 276 SUPERFAMILY SSF101478 1 232 2.48E-51 T 13-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily THITH_06955 bbd211acf6555b9e63f7a75934dbc99e 391 Gene3D G3DSA:3.40.50.970 2 247 1.2E-95 T 13-10-2018 THITH_06955 bbd211acf6555b9e63f7a75934dbc99e 391 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 262 357 2.1E-15 T 13-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II THITH_06955 bbd211acf6555b9e63f7a75934dbc99e 391 Gene3D G3DSA:3.40.50.920 250 374 8.9E-23 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 THITH_06955 bbd211acf6555b9e63f7a75934dbc99e 391 SUPERFAMILY SSF52922 249 367 3.45E-17 T 13-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 THITH_06955 bbd211acf6555b9e63f7a75934dbc99e 391 SUPERFAMILY SSF52518 4 244 1.0E-66 T 13-10-2018 IPR029061 Thiamin diphosphate-binding fold THITH_06955 bbd211acf6555b9e63f7a75934dbc99e 391 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 14 233 1.6E-69 T 13-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 THITH_12355 4e4a980806cf21e94dd65cc1032edaf7 504 Gene3D G3DSA:3.30.1330.140 379 495 4.0E-48 T 13-10-2018 THITH_12355 4e4a980806cf21e94dd65cc1032edaf7 504 Gene3D G3DSA:1.20.120.1310 32 137 2.0E-35 T 13-10-2018 THITH_12355 4e4a980806cf21e94dd65cc1032edaf7 504 Pfam PF08936 Carboxysome Shell Carbonic Anhydrase 44 492 1.6E-221 T 13-10-2018 IPR014074 Carboxysome shell carbonic anhydrase THITH_12355 4e4a980806cf21e94dd65cc1032edaf7 504 TIGRFAM TIGR02701 shell_carb_anhy: carboxysome shell carbonic anhydrase 44 482 1.5E-196 T 13-10-2018 IPR014074 Carboxysome shell carbonic anhydrase THITH_04920 517b3820aaee8220c1b0e99ad0464051 252 Gene3D G3DSA:3.40.50.720 4 249 8.0E-37 T 13-10-2018 THITH_04920 517b3820aaee8220c1b0e99ad0464051 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 178 195 1.8E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_04920 517b3820aaee8220c1b0e99ad0464051 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 131 147 1.8E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_04920 517b3820aaee8220c1b0e99ad0464051 252 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 1.8E-5 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_04920 517b3820aaee8220c1b0e99ad0464051 252 Pfam PF00106 short chain dehydrogenase 8 200 5.1E-25 T 13-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR THITH_04920 517b3820aaee8220c1b0e99ad0464051 252 SUPERFAMILY SSF51735 4 249 1.97E-39 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_16235 80db6648dca33bd5646d3b11efde0777 287 SUPERFAMILY SSF53474 28 215 1.79E-22 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_16235 80db6648dca33bd5646d3b11efde0777 287 Pfam PF07819 PGAP1-like protein 110 154 6.4E-8 T 13-10-2018 IPR012908 GPI inositol-deacylase PGAP1-like GO:0016788 Reactome: R-HSA-162791 THITH_05720 2a7e21cf07386be8a52c9b951578ca3d 99 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 31 90 4.1E-15 T 13-10-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system THITH_12250 0e46ad934140766d32ce13de7b2d22b3 236 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 4 217 5.9E-52 T 13-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 THITH_12250 0e46ad934140766d32ce13de7b2d22b3 236 SUPERFAMILY SSF53067 109 215 2.07E-14 T 13-10-2018 THITH_12250 0e46ad934140766d32ce13de7b2d22b3 236 Pfam PF00814 Glycoprotease family 31 148 2.8E-28 T 13-10-2018 IPR000905 Gcp-like domain THITH_12250 0e46ad934140766d32ce13de7b2d22b3 236 SUPERFAMILY SSF53067 1 102 2.2E-25 T 13-10-2018 THITH_12250 0e46ad934140766d32ce13de7b2d22b3 236 Gene3D G3DSA:3.30.420.40 95 186 1.1E-64 T 13-10-2018 THITH_12250 0e46ad934140766d32ce13de7b2d22b3 236 Gene3D G3DSA:3.30.420.40 3 217 1.1E-64 T 13-10-2018 THITH_00540 df61217e1e017770cadae25332653785 250 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 158 172 - T 13-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 THITH_00540 df61217e1e017770cadae25332653785 250 SUPERFAMILY SSF53335 17 248 9.76E-50 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_00540 df61217e1e017770cadae25332653785 250 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 25 248 6.6E-82 T 13-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 THITH_00540 df61217e1e017770cadae25332653785 250 Pfam PF01209 ubiE/COQ5 methyltransferase family 20 248 6.9E-94 T 13-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 THITH_00540 df61217e1e017770cadae25332653785 250 Gene3D G3DSA:3.40.50.150 31 250 3.7E-76 T 13-10-2018 THITH_00540 df61217e1e017770cadae25332653785 250 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 16 249 38.986 T 13-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 THITH_00540 df61217e1e017770cadae25332653785 250 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 36 51 - T 13-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 THITH_03355 01dcf72a57e6f6946db6bb8a4d44d174 65 Pfam PF09957 Bacterial antitoxin of type II TA system, VapB 1 46 3.7E-18 T 13-10-2018 IPR019239 Bacterial antitoxin of type II TA system, VapB THITH_03270 a67c4f8d6a525249acadb8d86cb8e6d4 607 SUPERFAMILY SSF74653 452 606 2.75E-22 T 13-10-2018 THITH_03270 a67c4f8d6a525249acadb8d86cb8e6d4 607 TIGRFAM TIGR01352 tonB_Cterm: TonB family C-terminal domain 529 605 8.7E-18 T 13-10-2018 IPR006260 TonB/TolA, C-terminal THITH_03270 a67c4f8d6a525249acadb8d86cb8e6d4 607 Pfam PF03544 Gram-negative bacterial TonB protein C-terminal 527 605 1.9E-15 T 13-10-2018 IPR037682 TonB, C-terminal GO:0055085 THITH_17450 73fc829ff8a8cf629929287a6c17bca2 208 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 5 208 18.099 T 13-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_17450 73fc829ff8a8cf629929287a6c17bca2 208 Pfam PF01813 ATP synthase subunit D 14 202 1.7E-41 T 13-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_17450 73fc829ff8a8cf629929287a6c17bca2 208 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 7 206 3.7E-30 T 13-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 THITH_10680 5ab14850124616eea87e0a9f7b09b72e 161 Gene3D G3DSA:3.40.140.10 8 161 3.0E-59 T 13-10-2018 THITH_10680 5ab14850124616eea87e0a9f7b09b72e 161 SUPERFAMILY SSF53927 11 159 5.85E-55 T 13-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 THITH_10680 5ab14850124616eea87e0a9f7b09b72e 161 Pfam PF14437 MafB19-like deaminase 14 159 3.7E-29 T 13-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 THITH_10680 5ab14850124616eea87e0a9f7b09b72e 161 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 63 100 - T 13-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 THITH_10680 5ab14850124616eea87e0a9f7b09b72e 161 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 18 159 44.989 T 13-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 THITH_04625 09a2af6016273b3883550d7d146218c4 112 Pfam PF04986 Putative transposase 1 49 1.2E-12 T 13-10-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THITH_04815 1d11d47605acaab33fd2b42faf63185f 194 Pfam PF09335 SNARE associated Golgi protein 57 156 1.0E-10 T 13-10-2018 IPR032816 SNARE associated Golgi protein THITH_14225 7063e8ad1a0f1963f403d8ca26f6114a 101 Gene3D G3DSA:4.10.830.10 39 101 1.0E-22 T 13-10-2018 THITH_14225 7063e8ad1a0f1963f403d8ca26f6114a 101 SUPERFAMILY SSF57716 2 101 2.57E-37 T 13-10-2018 THITH_14225 7063e8ad1a0f1963f403d8ca26f6114a 101 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 101 27.362 T 13-10-2018 IPR023036 Ribosomal protein S14, bacterial/plastid THITH_14225 7063e8ad1a0f1963f403d8ca26f6114a 101 Pfam PF00253 Ribosomal protein S14p/S29e 48 100 1.0E-25 T 13-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 THITH_06175 64aea0e15d02bb2b43d078fa5a3ea571 126 Pfam PF17228 Sulphur globule protein 32 123 3.9E-15 T 13-10-2018 IPR035173 Sulphur globule protein THITH_09625 254ca4786395f4c7bc456c6f170aa078 226 Pfam PF04298 Putative neutral zinc metallopeptidase 3 223 4.3E-70 T 13-10-2018 IPR007395 Putative neutral zinc metallopeptidase THITH_02345 8a19b74162bc86f08c37a002d8df370b 258 Gene3D G3DSA:3.40.50.1820 4 255 8.5E-52 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_02345 8a19b74162bc86f08c37a002d8df370b 258 Pfam PF12146 Serine aminopeptidase, S33 50 139 1.4E-11 T 13-10-2018 IPR022742 Serine aminopeptidase, S33 THITH_02345 8a19b74162bc86f08c37a002d8df370b 258 SUPERFAMILY SSF53474 7 255 6.71E-39 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_07565 d110feefb7fb7dfd152614c53b674afa 149 Pfam PF10116 Protein required for attachment to host cells 5 143 1.7E-40 T 13-10-2018 IPR019291 Host attachment protein THITH_10270 263e881429dfa232514e6c377d33405d 136 Gene3D G3DSA:3.40.30.10 44 136 7.3E-16 T 13-10-2018 THITH_10270 263e881429dfa232514e6c377d33405d 136 Pfam PF13417 Glutathione S-transferase, N-terminal domain 51 130 5.5E-13 T 13-10-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 THITH_10270 263e881429dfa232514e6c377d33405d 136 ProSitePatterns PS00195 Glutaredoxin active site. 51 67 - T 13-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 THITH_10270 263e881429dfa232514e6c377d33405d 136 SUPERFAMILY SSF52833 49 131 2.44E-20 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_07180 6c5e6d221f2a32c48707ef715e6abf24 115 Gene3D G3DSA:3.30.70.120 2 99 1.3E-11 T 13-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal THITH_07180 6c5e6d221f2a32c48707ef715e6abf24 115 SUPERFAMILY SSF54913 1 101 1.49E-14 T 13-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta THITH_07560 ceb9339f0dd17431ab05a6de7827d732 226 Pfam PF01694 Rhomboid family 62 213 1.5E-30 T 13-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 THITH_07560 ceb9339f0dd17431ab05a6de7827d732 226 SUPERFAMILY SSF144091 11 218 1.06E-41 T 13-10-2018 THITH_07560 ceb9339f0dd17431ab05a6de7827d732 226 Gene3D G3DSA:1.20.1540.10 10 215 1.4E-29 T 13-10-2018 IPR035952 Rhomboid-like superfamily THITH_07560 ceb9339f0dd17431ab05a6de7827d732 226 SMART SM01160 55 151 0.0015 T 13-10-2018 THITH_07310 43372c87f5c834f65a6a47f4ce4d0569 106 SUPERFAMILY SSF50022 1 103 2.88E-32 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THITH_07310 43372c87f5c834f65a6a47f4ce4d0569 106 Gene3D G3DSA:2.102.10.10 1 105 9.2E-34 T 13-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 THITH_07310 43372c87f5c834f65a6a47f4ce4d0569 106 Pfam PF00355 Rieske [2Fe-2S] domain 4 90 3.6E-19 T 13-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 THITH_02910 b98d2e79bb1c20a642e8a139ab87b568 227 Pfam PF01618 MotA/TolQ/ExbB proton channel family 77 203 1.5E-42 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel THITH_02910 b98d2e79bb1c20a642e8a139ab87b568 227 TIGRFAM TIGR02796 tolQ: protein TolQ 7 215 1.9E-85 T 13-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 THITH_02910 b98d2e79bb1c20a642e8a139ab87b568 227 Hamap MF_02202 Tol-Pal system protein TolQ [tolQ]. 5 220 43.381 T 13-10-2018 IPR014163 Tol-Pal system, TolQ GO:0016021|GO:0043213 THITH_14760 eea54a8a16ddb9dc89e4c0678ebfc610 108 PIRSF PIRSF005894 1 107 2.5E-47 T 13-10-2018 IPR014434 Monothiol glutaredoxin GO:0015036 Reactome: R-HSA-1362409 THITH_14760 eea54a8a16ddb9dc89e4c0678ebfc610 108 SUPERFAMILY SSF52833 1 103 1.97E-35 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_14760 eea54a8a16ddb9dc89e4c0678ebfc610 108 Pfam PF00462 Glutaredoxin 16 80 3.1E-18 T 13-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 THITH_14760 eea54a8a16ddb9dc89e4c0678ebfc610 108 Gene3D G3DSA:3.40.30.10 6 102 1.2E-31 T 13-10-2018 THITH_14760 eea54a8a16ddb9dc89e4c0678ebfc610 108 TIGRFAM TIGR00365 TIGR00365: monothiol glutaredoxin, Grx4 family 4 100 1.5E-44 T 13-10-2018 IPR004480 Monothiol glutaredoxin-related THITH_11315 fd17189b221e07598229ba3fbc2971b5 676 PIRSF PIRSF015380 2 673 1.2E-207 T 13-10-2018 IPR011385 Putative site-specific recombinase Gcr THITH_11315 fd17189b221e07598229ba3fbc2971b5 676 Pfam PF10136 Site-specific recombinase 22 659 8.5E-244 T 13-10-2018 IPR011385 Putative site-specific recombinase Gcr THITH_16650 cbaf15959dd3c5a392d2947385912b2f 341 Pfam PF13280 WYL domain 157 330 1.2E-33 T 13-10-2018 IPR026881 WYL domain THITH_03380 40ba9033930e23ae637a51a9b2f0378c 116 Pfam PF01934 Protein of unknown function DUF86 14 105 2.7E-19 T 13-10-2018 IPR008201 Protein of unknown function DUF86 THITH_05920 d617b45083c2f400ff3628314f93bc0c 80 Pfam PF14384 BrnA antitoxin of type II toxin-antitoxin system 20 78 1.5E-15 T 13-10-2018 IPR025528 BrnA antitoxin of type II toxin-antitoxin system THITH_13200 c8f3ee9caedcd3bed68717860fa639b8 129 Gene3D G3DSA:3.10.450.160 35 129 3.4E-30 T 13-10-2018 THITH_13200 c8f3ee9caedcd3bed68717860fa639b8 129 Pfam PF11776 Nickel/cobalt transporter regulator 76 122 5.2E-7 T 13-10-2018 IPR024572 Nickel/cobalt homeostasis protein RcnB THITH_14525 3d97637a6e9dc90ab7deceadefff2627 621 Gene3D G3DSA:3.40.50.2300 348 502 2.7E-53 T 13-10-2018 THITH_14525 3d97637a6e9dc90ab7deceadefff2627 621 Pfam PF04348 LppC putative lipoprotein 92 606 2.2E-67 T 13-10-2018 IPR007443 Penicillin-binding protein activator LpoA THITH_14525 3d97637a6e9dc90ab7deceadefff2627 621 Gene3D G3DSA:3.40.50.2300 247 584 2.7E-53 T 13-10-2018 THITH_14525 3d97637a6e9dc90ab7deceadefff2627 621 SUPERFAMILY SSF53822 244 609 3.1E-54 T 13-10-2018 IPR028082 Periplasmic binding protein-like I THITH_14525 3d97637a6e9dc90ab7deceadefff2627 621 Gene3D G3DSA:1.25.40.650 134 239 1.1E-11 T 13-10-2018 THITH_02665 68fa2c84261b5c8f1547ce2fd6f7b25d 266 Pfam PF01578 Cytochrome C assembly protein 44 262 2.7E-23 T 13-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 THITH_16065 fac9ecb86ffb59b6d3dcace599c5f3ab 220 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 8 213 1.1E-55 T 13-10-2018 IPR039447 Urease accessory protein UreH-like, transmembrane domain THITH_04265 f3a4a03ed6ce27bf663adf9f50b045a2 48 Gene3D G3DSA:1.10.1200.10 1 48 5.7E-16 T 13-10-2018 IPR036736 ACP-like superfamily THITH_04265 f3a4a03ed6ce27bf663adf9f50b045a2 48 SUPERFAMILY SSF47336 2 45 6.15E-10 T 13-10-2018 IPR036736 ACP-like superfamily THITH_04265 f3a4a03ed6ce27bf663adf9f50b045a2 48 Pfam PF00550 Phosphopantetheine attachment site 2 42 4.9E-5 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain THITH_16515 049c68b8ab2d66aa06590e0198e7c748 73 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 15 54 1.5E-9 T 13-10-2018 IPR008621 Cbb3-type cytochrome oxidase component THITH_03455 62c17582bef386be71645012805ec117 96 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 9 74 4.5E-6 T 13-10-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system THITH_05960 571dceae756869f7238a71332b16a029 128 PIRSF PIRSF018634 2 125 8.9E-42 T 13-10-2018 IPR009387 Toxin HigB-2 THITH_05960 571dceae756869f7238a71332b16a029 128 Pfam PF06296 RelE toxin of RelE / RelB toxin-antitoxin system 3 120 1.2E-44 T 13-10-2018 IPR009387 Toxin HigB-2 THITH_15730 336de5b5793cc918b7504ed5552c7d48 78 ProDom PD030374 YCGL UNCHARACTERIZED SIMILAR BACTERIA HI1446 Y2231 HYDROLASE CYTOPLASMIC YPO2080 SO2575 3 78 4.0E-16 T 13-10-2018 IPR027354 YcgL domain THITH_15730 336de5b5793cc918b7504ed5552c7d48 78 Hamap MF_01866 Protein YcgL [ycgL]. 1 78 20.806 T 13-10-2018 IPR027354 YcgL domain THITH_15730 336de5b5793cc918b7504ed5552c7d48 78 SUPERFAMILY SSF160191 2 78 9.94E-28 T 13-10-2018 IPR038068 YcgL-like superfamily THITH_15730 336de5b5793cc918b7504ed5552c7d48 78 Pfam PF05166 YcgL domain 3 75 5.1E-27 T 13-10-2018 IPR027354 YcgL domain THITH_15730 336de5b5793cc918b7504ed5552c7d48 78 Gene3D G3DSA:3.10.510.20 1 74 1.1E-25 T 13-10-2018 IPR038068 YcgL-like superfamily THITH_16015 de6907507bdc28fec571289742279bab 168 SUPERFAMILY SSF53271 4 151 5.51E-34 T 13-10-2018 IPR029057 Phosphoribosyltransferase-like THITH_16015 de6907507bdc28fec571289742279bab 168 Gene3D G3DSA:3.40.50.2020 1 166 9.0E-41 T 13-10-2018 THITH_16015 de6907507bdc28fec571289742279bab 168 Pfam PF00156 Phosphoribosyl transferase domain 7 134 2.0E-18 T 13-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 THITH_01590 7f0b70c702003c1f79f8136a12af86dd 827 SUPERFAMILY SSF53955 652 757 2.59E-29 T 13-10-2018 IPR023346 Lysozyme-like domain superfamily THITH_01590 7f0b70c702003c1f79f8136a12af86dd 827 Gene3D G3DSA:1.10.530.10 654 780 2.2E-26 T 13-10-2018 THITH_01590 7f0b70c702003c1f79f8136a12af86dd 827 Pfam PF01464 Transglycosylase SLT domain 662 756 8.6E-19 T 13-10-2018 IPR008258 Transglycosylase SLT domain 1 THITH_06525 a5b066dbae1a4687931a649ee18d3c63 819 SUPERFAMILY SSF53300 28 178 1.06E-19 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily THITH_06525 a5b066dbae1a4687931a649ee18d3c63 819 SMART SM00327 27 200 1.5E-7 T 13-10-2018 IPR002035 von Willebrand factor, type A THITH_06525 a5b066dbae1a4687931a649ee18d3c63 819 Gene3D G3DSA:3.40.50.410 25 208 7.2E-28 T 13-10-2018 IPR036465 von Willebrand factor A-like domain superfamily THITH_06525 a5b066dbae1a4687931a649ee18d3c63 819 Pfam PF13519 von Willebrand factor type A domain 29 141 2.2E-10 T 13-10-2018 IPR002035 von Willebrand factor, type A THITH_06560 1fdf05e29545c5c0350ba76978ffbd2b 985 Gene3D G3DSA:3.40.1090.10 37 136 1.4E-8 T 13-10-2018 THITH_06560 1fdf05e29545c5c0350ba76978ffbd2b 985 SUPERFAMILY SSF52151 31 957 5.23E-25 T 13-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase THITH_13365 ebc89762f6834df010122c188a35b832 232 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 7 218 4.9E-49 T 13-10-2018 IPR039447 Urease accessory protein UreH-like, transmembrane domain THITH_01450 9c05b8a3afd0b11591307421a56f3185 65 Pfam PF14255 Cysteine-rich CPXCG 12 58 2.1E-17 T 13-10-2018 IPR025990 Cysteine-rich CPXCG protein THITH_00690 99e00edabc7108da55fc02adf1ef39f5 304 SUPERFAMILY SSF53448 14 212 7.03E-11 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_10035 4940888a2767de911818d1ff41aff0f9 395 Pfam PF00005 ABC transporter 38 168 6.3E-17 T 13-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 THITH_10035 4940888a2767de911818d1ff41aff0f9 395 SMART SM00382 45 217 5.6E-11 T 13-10-2018 IPR003593 AAA+ ATPase domain THITH_10035 4940888a2767de911818d1ff41aff0f9 395 SUPERFAMILY SSF52540 12 233 1.81E-46 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_10035 4940888a2767de911818d1ff41aff0f9 395 Gene3D G3DSA:3.40.50.300 21 257 7.0E-43 T 13-10-2018 THITH_02245 c701fe763451e901ecfcf3ad6da66118 391 SMART SM01321 13 189 3.7E-4 T 13-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 THITH_02245 c701fe763451e901ecfcf3ad6da66118 391 SUPERFAMILY SSF143422 16 194 2.55E-16 T 13-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 THITH_06080 90c57d1305b41412065ed63064b344b7 109 PRINTS PR01853 Bacterial YajC preprotein translocase signature 21 41 1.5E-14 T 13-10-2018 IPR003849 Preprotein translocase YajC THITH_06080 90c57d1305b41412065ed63064b344b7 109 PRINTS PR01853 Bacterial YajC preprotein translocase signature 59 77 1.5E-14 T 13-10-2018 IPR003849 Preprotein translocase YajC THITH_06080 90c57d1305b41412065ed63064b344b7 109 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 22 101 2.4E-26 T 13-10-2018 IPR003849 Preprotein translocase YajC THITH_06080 90c57d1305b41412065ed63064b344b7 109 SMART SM01323 19 101 5.5E-41 T 13-10-2018 IPR003849 Preprotein translocase YajC THITH_06080 90c57d1305b41412065ed63064b344b7 109 Pfam PF02699 Preprotein translocase subunit 24 98 1.5E-27 T 13-10-2018 IPR003849 Preprotein translocase YajC THITH_05500 6cc2ccc06f2c6123a3bc26762c9810c6 323 Pfam PF11199 Protein of unknown function (DUF2891) 1 312 3.3E-124 T 13-10-2018 IPR021365 Protein of unknown function DUF2891 THITH_08105 7d19befcfc8993a1298cf108bd599edb 307 Pfam PF01136 Peptidase family U32 97 246 8.3E-16 T 13-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 THITH_16710 ce72ca65d607fc4c8267520f1237f811 77 Pfam PF13192 Thioredoxin domain 3 76 2.2E-25 T 13-10-2018 IPR012336 Thioredoxin-like fold THITH_16710 ce72ca65d607fc4c8267520f1237f811 77 SUPERFAMILY SSF52833 3 76 2.95E-19 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_16710 ce72ca65d607fc4c8267520f1237f811 77 PIRSF PIRSF037031 1 77 9.8E-28 T 13-10-2018 IPR005243 Redox-active disulphide protein 2 THITH_16710 ce72ca65d607fc4c8267520f1237f811 77 Gene3D G3DSA:3.40.30.10 1 76 4.0E-25 T 13-10-2018 THITH_07580 f2a7b5509c1872f2ac524c2010c70334 144 Pfam PF14347 Domain of unknown function (DUF4399) 52 144 5.9E-35 T 13-10-2018 IPR025512 Domain of unknown function DUF4399 THITH_05370 ca33184c0d2dab98ecb36d700412f22e 92 SUPERFAMILY SSF47598 8 85 2.67E-18 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 THITH_05370 ca33184c0d2dab98ecb36d700412f22e 92 Pfam PF08681 Protein of unknown function (DUF1778) 11 86 5.3E-24 T 13-10-2018 IPR014795 Vibrio phage ICP1, Orf50 THITH_05370 ca33184c0d2dab98ecb36d700412f22e 92 Gene3D G3DSA:1.20.5.780 6 87 9.8E-16 T 13-10-2018 THITH_09100 3b7dbf9368da451e1b08f0b687431501 442 Pfam PF02646 RmuC family 118 408 7.6E-91 T 13-10-2018 IPR003798 DNA recombination RmuC THITH_09945 b87128fc1a6f89fe97e57396d6e3dc3d 581 Gene3D G3DSA:3.90.550.10 54 283 9.3E-19 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_09945 b87128fc1a6f89fe97e57396d6e3dc3d 581 Pfam PF00535 Glycosyl transferase family 2 60 242 3.2E-15 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THITH_09945 b87128fc1a6f89fe97e57396d6e3dc3d 581 SUPERFAMILY SSF53448 58 345 3.25E-28 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_11595 fca7c7f6d4353085004deefafc81abf4 222 Gene3D G3DSA:3.20.20.70 18 160 1.5E-29 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_11595 fca7c7f6d4353085004deefafc81abf4 222 SUPERFAMILY SSF51395 31 162 9.52E-32 T 13-10-2018 THITH_11595 fca7c7f6d4353085004deefafc81abf4 222 Pfam PF01645 Conserved region in glutamate synthase 32 133 1.1E-22 T 13-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 THITH_09930 24a40d317402e91ba6993c0d5b3caad3 323 SUPERFAMILY SSF56059 106 257 2.3E-6 T 13-10-2018 THITH_05915 3107f768834d00b4f9940f002e0c2421 91 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 5 81 6.2E-17 T 13-10-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system THITH_05915 3107f768834d00b4f9940f002e0c2421 91 Gene3D G3DSA:3.10.450.530 1 84 9.5E-11 T 13-10-2018 IPR038573 Ribonuclease toxin BrnT superfamily THITH_08050 7d083957295dec298de8a3d7cf35b473 307 Pfam PF04381 Putative exonuclease, RdgC 1 298 6.3E-113 T 13-10-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 THITH_08050 7d083957295dec298de8a3d7cf35b473 307 Hamap MF_00194 Recombination-associated protein RdgC [rdgC]. 1 301 37.606 T 13-10-2018 IPR007476 Putative exonuclease, RdgC GO:0006310 THITH_16105 85ebc58eda11b18c690bbec1bcedebf4 175 Pfam PF06271 RDD family 12 136 1.5E-13 T 13-10-2018 IPR010432 RDD THITH_10860 7926776367f63e0b4743befcbbdb2223 124 Pfam PF07603 Protein of unknown function (DUF1566) 1 121 2.2E-31 T 13-10-2018 IPR011460 Protein of unknown function DUF1566 THITH_01710 2fd6e66299f21bd9eae6d7a01878135d 462 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 151 176 - T 13-10-2018 IPR018212 Sodium/solute symporter, conserved site THITH_01710 2fd6e66299f21bd9eae6d7a01878135d 462 Gene3D G3DSA:1.20.1730.10 28 447 6.1E-18 T 13-10-2018 IPR038377 Sodium/glucose symporter superfamily THITH_13545 2da5ea334090d0c1306990311977c389 787 Pfam PF02687 FtsX-like permease family 294 387 2.3E-10 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THITH_13545 2da5ea334090d0c1306990311977c389 787 Pfam PF02687 FtsX-like permease family 687 775 1.5E-11 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THITH_12870 eddfe2cd7157cf18b53ed3c1f32b5ef3 312 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 306 8.6E-80 T 13-10-2018 IPR007296 Domain of unknown function DUF403 THITH_09230 4f9da2f1b9db55f3c30bbcaec0b21006 304 Gene3D G3DSA:3.40.50.1820 12 302 3.9E-41 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_09230 4f9da2f1b9db55f3c30bbcaec0b21006 304 Pfam PF01764 Lipase (class 3) 139 223 7.0E-12 T 13-10-2018 IPR002921 Fungal lipase-like domain GO:0006629 Reactome: R-HSA-426048 THITH_09230 4f9da2f1b9db55f3c30bbcaec0b21006 304 SUPERFAMILY SSF53474 54 227 6.12E-16 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_09355 9573749bdf92986035b7cefc6294db32 898 TIGRFAM TIGR02578 cas_TM1811_Csm1: CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE 17 766 6.0E-142 T 13-10-2018 IPR013408 CRISPR-associated protein Csm1 THITH_09355 9573749bdf92986035b7cefc6294db32 898 Gene3D G3DSA:3.30.70.2230 623 772 2.4E-33 T 13-10-2018 THITH_02265 2db8df940a66ac9c60ed0b7788e16454 431 Pfam PF14341 PilX N-terminal 16 66 5.7E-6 T 13-10-2018 IPR025746 Type 4 fimbrial biogenesis protein PilX, N-terminal domain THITH_07810 eeebf3a40ed6de0e8ffc7eb6714145bc 449 Gene3D G3DSA:3.40.50.11380 38 383 1.8E-110 T 13-10-2018 THITH_07810 eeebf3a40ed6de0e8ffc7eb6714145bc 449 Pfam PF13844 Glycosyl transferase family 41 47 190 2.3E-19 T 13-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 THITH_07810 eeebf3a40ed6de0e8ffc7eb6714145bc 449 Pfam PF13844 Glycosyl transferase family 41 217 393 8.4E-16 T 13-10-2018 IPR029489 O-GlcNAc transferase, C-terminal KEGG: 00514+2.4.1.255|MetaCyc: PWY-7437|Reactome: R-HSA-3214847|Reactome: R-HSA-5689603 THITH_07810 eeebf3a40ed6de0e8ffc7eb6714145bc 449 SUPERFAMILY SSF53756 225 394 2.2E-6 T 13-10-2018 THITH_07810 eeebf3a40ed6de0e8ffc7eb6714145bc 449 Gene3D G3DSA:3.40.50.2000 206 380 1.8E-110 T 13-10-2018 THITH_07790 9b5d91f43a8939b9675e73619832f049 185 SUPERFAMILY SSF51182 70 165 2.45E-16 T 13-10-2018 IPR011051 RmlC-like cupin domain superfamily THITH_07790 9b5d91f43a8939b9675e73619832f049 185 Gene3D G3DSA:2.60.120.10 41 175 2.6E-16 T 13-10-2018 IPR014710 RmlC-like jelly roll fold THITH_07790 9b5d91f43a8939b9675e73619832f049 185 Pfam PF07883 Cupin domain 80 148 1.1E-7 T 13-10-2018 IPR013096 Cupin 2, conserved barrel THITH_16500 cb8afd1a5007c0d8b4dbf50e8f05bfbf 274 Pfam PF05751 FixH 164 263 1.0E-10 T 13-10-2018 IPR008620 Nitrogen fixation protein FixH THITH_16260 127aea00bbfd58d7bbcf80cf3cd8df6a 319 SUPERFAMILY SSF48452 37 303 6.4E-5 T 13-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 THITH_17170 56b656799702319abd0f3312bb81a6c7 291 SUPERFAMILY SSF56219 22 271 5.63E-36 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily THITH_17170 56b656799702319abd0f3312bb81a6c7 291 Gene3D G3DSA:3.60.10.10 27 273 6.0E-39 T 13-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily THITH_17170 56b656799702319abd0f3312bb81a6c7 291 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 62 261 2.4E-17 T 13-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase THITH_03670 91658f9c80eb10a75f2986cc3950649b 399 SUPERFAMILY SSF50939 84 220 3.01E-14 T 13-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 THITH_03670 91658f9c80eb10a75f2986cc3950649b 399 Gene3D G3DSA:2.120.10.10 24 255 2.8E-9 T 13-10-2018 THITH_02460 316a3523adc7ff88975045ccadc375e8 147 Gene3D G3DSA:1.10.10.10 89 146 4.1E-6 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_10435 647cb28b468d0e03fe2c62a46998fef0 278 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 229 255 - T 13-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 THITH_10435 647cb28b468d0e03fe2c62a46998fef0 278 Pfam PF01148 Cytidylyltransferase family 3 266 5.3E-51 T 13-10-2018 THITH_15865 6f88b1ceaaa4ac32b8048fc512f1504d 159 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 129 7.9E-34 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type THITH_15865 6f88b1ceaaa4ac32b8048fc512f1504d 159 SUPERFAMILY SSF46785 2 132 9.74E-30 T 13-10-2018 IPR036390 Winged helix DNA-binding domain superfamily THITH_15865 6f88b1ceaaa4ac32b8048fc512f1504d 159 Pfam PF02082 Transcriptional regulator 1 83 9.7E-27 T 13-10-2018 IPR000944 Transcription regulator Rrf2-type THITH_15865 6f88b1ceaaa4ac32b8048fc512f1504d 159 Gene3D G3DSA:1.10.10.10 1 143 2.4E-43 T 13-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily THITH_16325 e0ffc1b4f43aa34bb01cf4ce6cf591ef 279 Pfam PF08241 Methyltransferase domain 70 168 9.2E-21 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 THITH_16325 e0ffc1b4f43aa34bb01cf4ce6cf591ef 279 Gene3D G3DSA:3.40.50.150 18 277 1.9E-66 T 13-10-2018 THITH_16325 e0ffc1b4f43aa34bb01cf4ce6cf591ef 279 SUPERFAMILY SSF53335 10 277 4.45E-58 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_05515 75361250e4098dc7181d6fc3f3fc0670 510 Pfam PF14264 Glucosyl transferase GtrII 38 340 1.2E-31 T 13-10-2018 IPR025686 Glucosyl transferase II THITH_05290 ba013ccf1d0ff9ae858d06e7242f26b7 124 SUPERFAMILY SSF158791 26 118 7.19E-6 T 13-10-2018 THITH_13775 fc6cb6127b3e0117bf2ad5f920f8b416 328 Pfam PF09614 CRISPR-associated protein (Cas_Csy2) 11 317 1.1E-106 T 13-10-2018 IPR013398 CRISPR-associated protein Csy2 THITH_13775 fc6cb6127b3e0117bf2ad5f920f8b416 328 TIGRFAM TIGR02565 cas_Csy2: CRISPR type I-F/YPEST-associated protein Csy2 11 319 5.7E-85 T 13-10-2018 IPR013398 CRISPR-associated protein Csy2 THITH_11530 4e2060095bbe45464b34fd659705f4c3 202 Pfam PF07681 DoxX 23 111 3.8E-20 T 13-10-2018 IPR032808 DoxX family THITH_06855 0eac7a546a9e785257d63846cd0644a7 616 Pfam PF02690 Na+/Pi-cotransporter 199 276 5.3E-8 T 13-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 THITH_06855 0eac7a546a9e785257d63846cd0644a7 616 Pfam PF02690 Na+/Pi-cotransporter 32 171 2.1E-34 T 13-10-2018 IPR003841 Sodium-dependent phosphate transport protein GO:0015321|GO:0016020|GO:0044341 Reactome: R-HSA-427589 THITH_05145 231f3ca3df31d75c241231d8fa2db762 98 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 87 2.2E-10 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THITH_05145 231f3ca3df31d75c241231d8fa2db762 98 Gene3D G3DSA:3.30.2310.20 1 91 2.6E-9 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_08695 ff6e20251d92bb55fa96e9e3308bc98c 454 Gene3D G3DSA:3.20.20.70 92 387 9.9E-74 T 13-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 THITH_08695 ff6e20251d92bb55fa96e9e3308bc98c 454 SUPERFAMILY SSF102114 160 382 3.01E-10 T 13-10-2018 THITH_01540 083c9536ec5522fa4faaa7a9664414e7 273 Pfam PF08273 Zinc-binding domain of primase-helicase 35 72 5.5E-7 T 13-10-2018 IPR013237 Bacteriophage T7, Gp4, DNA primase/helicase, N-terminal GO:0003896|GO:0004386|GO:0008270 THITH_01540 083c9536ec5522fa4faaa7a9664414e7 273 SUPERFAMILY SSF57783 15 100 8.5E-12 T 13-10-2018 THITH_01540 083c9536ec5522fa4faaa7a9664414e7 273 SMART SM00778 35 73 2.9E-5 T 13-10-2018 IPR013237 Bacteriophage T7, Gp4, DNA primase/helicase, N-terminal GO:0003896|GO:0004386|GO:0008270 THITH_04795 a4a5290916d19123a65249c2db134205 192 Pfam PF11845 Protein of unknown function (DUF3365) 13 189 2.7E-30 T 13-10-2018 IPR021796 Protein of unknown function DUF3365 THITH_10605 4c0264a6f36e69f75af2d9669afc4ec5 264 Gene3D G3DSA:1.20.1300.10 9 250 2.0E-75 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_10605 4c0264a6f36e69f75af2d9669afc4ec5 264 PIRSF PIRSF000177 6 251 9.0E-83 T 13-10-2018 IPR004224 Fumarate reductase type B, transmembrane subunit GO:0006099 THITH_10605 4c0264a6f36e69f75af2d9669afc4ec5 264 SUPERFAMILY SSF81343 20 241 6.28E-66 T 13-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_10605 4c0264a6f36e69f75af2d9669afc4ec5 264 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 108 221 3.1E-13 T 13-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 THITH_01705 1ee0bb812f9058bc25fdfc65b292e1ce 349 SUPERFAMILY SSF56300 34 272 1.42E-12 T 13-10-2018 THITH_14600 3fde7aabf64d42835d05366ddb2fb16d 59 SUPERFAMILY SSF52091 1 54 4.91E-10 T 13-10-2018 IPR036513 STAS domain superfamily THITH_14600 3fde7aabf64d42835d05366ddb2fb16d 59 Gene3D G3DSA:3.30.750.24 1 57 1.8E-9 T 13-10-2018 IPR036513 STAS domain superfamily THITH_14600 3fde7aabf64d42835d05366ddb2fb16d 59 Pfam PF13466 STAS domain 1 49 5.4E-11 T 13-10-2018 IPR002645 STAS domain THITH_01060 25fa603e67d340799b8d7012428fe0fc 108 TIGRFAM TIGR02684 dnstrm_HI1420: probable addiction module antidote protein 6 94 3.3E-36 T 13-10-2018 IPR014057 Uncharacterized protein HI1420 THITH_01060 25fa603e67d340799b8d7012428fe0fc 108 SUPERFAMILY SSF47413 36 92 6.65E-9 T 13-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 THITH_01060 25fa603e67d340799b8d7012428fe0fc 108 Pfam PF01381 Helix-turn-helix 49 92 5.0E-5 T 13-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 THITH_06030 38f6d4a87850d19b5cacaa19daf16491 227 Pfam PF02397 Bacterial sugar transferase 3 196 1.7E-48 T 13-10-2018 IPR003362 Bacterial sugar transferase THITH_05660 7be56407e0eb64357948ab4d46f7521b 201 Pfam PF13707 RloB-like protein 19 191 9.2E-29 T 13-10-2018 IPR025591 RloB-like protein THITH_08260 cd047391ec5d9c1b0e5c8cf8ee542d7c 722 SUPERFAMILY SSF52540 33 267 6.82E-10 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_09560 a0488846e3cb90988e7f48fefee89f70 223 Pfam PF02163 Peptidase family M50 134 193 2.3E-7 T 13-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 THITH_03055 aec5f02a4303bc88ac58a122b0407910 228 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 31 217 2.5E-14 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THITH_03055 aec5f02a4303bc88ac58a122b0407910 228 Gene3D G3DSA:1.10.3720.10 4 225 9.1E-50 T 13-10-2018 IPR035906 MetI-like superfamily THITH_03055 aec5f02a4303bc88ac58a122b0407910 228 SUPERFAMILY SSF161098 6 218 1.31E-42 T 13-10-2018 IPR035906 MetI-like superfamily THITH_03055 aec5f02a4303bc88ac58a122b0407910 228 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 14 222 4.9E-65 T 13-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 THITH_04305 572ce369a15eb1b09b19526d07c638a4 320 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 90 238 9.5E-5 T 13-10-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 THITH_08510 6c97479298b73fd9af48ae23dad8388a 414 Pfam PF02687 FtsX-like permease family 310 407 1.0E-12 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THITH_08510 6c97479298b73fd9af48ae23dad8388a 414 Pfam PF12704 MacB-like periplasmic core domain 19 246 1.7E-17 T 13-10-2018 IPR025857 MacB-like periplasmic core domain THITH_00160 efe172a14e17b6b5dd0d6703689b37c3 246 Gene3D G3DSA:1.10.357.10 107 236 3.5E-5 T 13-10-2018 THITH_04645 c88fe6d36e6c04faf7f872d1b45cee2d 308 SUPERFAMILY SSF51430 42 292 5.37E-43 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily THITH_04645 c88fe6d36e6c04faf7f872d1b45cee2d 308 Pfam PF00248 Aldo/keto reductase family 48 291 1.5E-24 T 13-10-2018 IPR023210 NADP-dependent oxidoreductase domain THITH_04645 c88fe6d36e6c04faf7f872d1b45cee2d 308 Gene3D G3DSA:3.20.20.100 41 306 5.1E-37 T 13-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily THITH_05325 12ad7dcb9be19bbfe062a6da54aa1cb2 834 Pfam PF02687 FtsX-like permease family 272 364 1.7E-7 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THITH_05325 12ad7dcb9be19bbfe062a6da54aa1cb2 834 Pfam PF02687 FtsX-like permease family 732 825 4.3E-11 T 13-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 THITH_05325 12ad7dcb9be19bbfe062a6da54aa1cb2 834 Pfam PF12704 MacB-like periplasmic core domain 470 671 6.0E-10 T 13-10-2018 IPR025857 MacB-like periplasmic core domain THITH_03465 72752beafefa760bee09ff5859172240 415 Gene3D G3DSA:1.20.1440.110 19 129 1.6E-26 T 13-10-2018 THITH_03465 72752beafefa760bee09ff5859172240 415 Pfam PF06500 Alpha/beta hydrolase of unknown function (DUF1100) 78 265 8.0E-7 T 13-10-2018 IPR010520 UPF0255 family THITH_03465 72752beafefa760bee09ff5859172240 415 SUPERFAMILY SSF53474 22 407 1.23E-54 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_03465 72752beafefa760bee09ff5859172240 415 Gene3D G3DSA:3.40.50.1820 133 409 2.4E-61 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_04135 6518575c19b42f245b6b1212db297189 314 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 187 293 4.6E-16 T 13-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein THITH_04135 6518575c19b42f245b6b1212db297189 314 Pfam PF13244 Domain of unknown function (DUF4040) 15 78 4.0E-18 T 13-10-2018 IPR025383 Domain of unknown function DUF4040 THITH_03485 3c3856b2904db5c068be395912b956f7 131 Gene3D G3DSA:3.30.56.110 9 131 1.5E-54 T 13-10-2018 THITH_03485 3c3856b2904db5c068be395912b956f7 131 Pfam PF09996 Uncharacterized protein conserved in bacteria (DUF2237) 13 127 7.9E-54 T 13-10-2018 IPR018714 Protein of unknown function DUF2237 THITH_12095 c7c4a21ecb57d62bf8b1eaf5c8a798d2 210 Pfam PF01618 MotA/TolQ/ExbB proton channel family 68 189 6.7E-35 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel THITH_01105 572d0f43e14278b318e4095feb02bc37 1666 SUPERFAMILY SSF53335 318 1121 8.11E-41 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_01105 572d0f43e14278b318e4095feb02bc37 1666 Gene3D G3DSA:3.40.50.150 545 724 9.3E-20 T 13-10-2018 THITH_01105 572d0f43e14278b318e4095feb02bc37 1666 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 983 989 - T 13-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 THITH_09955 db56537fea87f31c39625cc72efd7888 526 Gene3D G3DSA:3.40.720.10 220 499 2.3E-12 T 13-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 THITH_09955 db56537fea87f31c39625cc72efd7888 526 SUPERFAMILY SSF53649 244 483 2.88E-8 T 13-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 THITH_15285 5e8fe2cf385cce018428e5f3a3543f1f 179 Gene3D G3DSA:3.40.30.10 37 179 1.5E-27 T 13-10-2018 THITH_15285 5e8fe2cf385cce018428e5f3a3543f1f 179 Pfam PF13098 Thioredoxin-like domain 56 156 3.6E-16 T 13-10-2018 IPR012336 Thioredoxin-like fold THITH_15285 5e8fe2cf385cce018428e5f3a3543f1f 179 SUPERFAMILY SSF52833 28 173 3.7E-20 T 13-10-2018 IPR036249 Thioredoxin-like superfamily THITH_04005 04e6c93643f429d1d6a51229c33fe2f9 185 PIRSF PIRSF028288 7 184 1.5E-72 T 13-10-2018 IPR016878 Uncharacterised conserved protein UCP028288 THITH_04005 04e6c93643f429d1d6a51229c33fe2f9 185 Gene3D G3DSA:3.10.450.50 19 184 1.2E-19 T 13-10-2018 THITH_16825 6813e4ccb79f1338f756e4eb421fd7fb 144 Pfam PF11736 Protein of unknown function (DUF3299) 3 142 5.9E-41 T 13-10-2018 IPR021727 Protein of unknown function DUF3299 THITH_16825 6813e4ccb79f1338f756e4eb421fd7fb 144 Gene3D G3DSA:2.40.50.870 1 144 3.4E-45 T 13-10-2018 THITH_01510 a8baf04a24e2d71e27a8e03c842bd3ba 196 Gene3D G3DSA:3.30.530.20 36 194 8.2E-9 T 13-10-2018 IPR023393 START-like domain superfamily THITH_01510 a8baf04a24e2d71e27a8e03c842bd3ba 196 SUPERFAMILY SSF55961 38 183 5.75E-10 T 13-10-2018 THITH_01510 a8baf04a24e2d71e27a8e03c842bd3ba 196 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 44 139 4.4E-5 T 13-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 THITH_13190 1b192614d38737f4a38e8fd6de4d58d4 240 SUPERFAMILY SSF53335 86 191 2.36E-11 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_13190 1b192614d38737f4a38e8fd6de4d58d4 240 Gene3D G3DSA:3.40.50.150 38 176 3.5E-10 T 13-10-2018 THITH_13190 1b192614d38737f4a38e8fd6de4d58d4 240 Pfam PF08241 Methyltransferase domain 81 129 5.9E-5 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 THITH_01405 c6b04f7faa29cea0eb832b0852736f67 277 SUPERFAMILY SSF103501 80 225 1.7E-5 T 13-10-2018 IPR036197 NarG-like superfamily THITH_06795 622625d80983d325c8cf3bfd119a198f 119 Gene3D G3DSA:3.30.2320.80 1 114 7.1E-30 T 13-10-2018 THITH_06795 622625d80983d325c8cf3bfd119a198f 119 TIGRFAM TIGR00100 hypA: hydrogenase nickel insertion protein HypA 1 112 9.6E-30 T 13-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 THITH_06795 622625d80983d325c8cf3bfd119a198f 119 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 13-10-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site THITH_06795 622625d80983d325c8cf3bfd119a198f 119 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 113 20.343 T 13-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 THITH_06795 622625d80983d325c8cf3bfd119a198f 119 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 112 8.8E-30 T 13-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 THITH_06795 622625d80983d325c8cf3bfd119a198f 119 PIRSF PIRSF004761 1 116 2.7E-34 T 13-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 THITH_09185 2c05bba39c8a4311be0483295a1c058d 131 SUPERFAMILY SSF49764 19 130 3.84E-29 T 13-10-2018 IPR008978 HSP20-like chaperone THITH_09185 2c05bba39c8a4311be0483295a1c058d 131 Gene3D G3DSA:2.60.40.790 1 129 4.7E-28 T 13-10-2018 IPR008978 HSP20-like chaperone THITH_09185 2c05bba39c8a4311be0483295a1c058d 131 Pfam PF00011 Hsp20/alpha crystallin family 31 129 1.8E-18 T 13-10-2018 IPR002068 Alpha crystallin/Hsp20 domain THITH_02180 b1315f034ef11aefbecb10e6a01d3335 87 Gene3D G3DSA:1.10.1220.10 5 79 2.6E-15 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THITH_02180 b1315f034ef11aefbecb10e6a01d3335 87 Pfam PF04221 RelB antitoxin 4 76 3.3E-26 T 13-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ THITH_02180 b1315f034ef11aefbecb10e6a01d3335 87 TIGRFAM TIGR02384 RelB_DinJ: addiction module antitoxin, RelB/DinJ family 4 83 5.8E-25 T 13-10-2018 IPR007337 RelB antitoxin/Antitoxin DinJ THITH_02180 b1315f034ef11aefbecb10e6a01d3335 87 PIRSF PIRSF003108 1 87 2.3E-32 T 13-10-2018 IPR026262 Antitoxin DinJ GO:0000986|GO:0015643|GO:0044010 THITH_14470 254a7f50888e27f17c021a1f0463eabd 390 Pfam PF01098 Cell cycle protein 23 378 4.8E-102 T 13-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_14470 254a7f50888e27f17c021a1f0463eabd 390 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 21 377 3.9E-125 T 13-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_14470 254a7f50888e27f17c021a1f0463eabd 390 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 336 360 - T 13-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_14470 254a7f50888e27f17c021a1f0463eabd 390 Hamap MF_00913 Probable peptidoglycan glycosyltransferase FtsW [ftsW]. 18 387 40.013 T 13-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 THITH_13165 6c00ed654c159e63773d8887627ea393 147 Gene3D G3DSA:3.30.530.20 4 144 1.5E-41 T 13-10-2018 IPR023393 START-like domain superfamily THITH_13165 6c00ed654c159e63773d8887627ea393 147 SUPERFAMILY SSF55961 1 145 1.61E-39 T 13-10-2018 THITH_13165 6c00ed654c159e63773d8887627ea393 147 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 11 134 3.2E-35 T 13-10-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 THITH_02425 73054f6f313c32d5702ce736f87381de 204 Gene3D G3DSA:3.40.50.10490 2 193 6.4E-72 T 13-10-2018 THITH_02425 73054f6f313c32d5702ce736f87381de 204 SUPERFAMILY SSF53697 4 186 1.07E-54 T 13-10-2018 THITH_02425 73054f6f313c32d5702ce736f87381de 204 Hamap MF_00067 Phosphoheptose isomerase [gmhA]. 1 188 36.389 T 13-10-2018 IPR004515 Phosphoheptose isomerase GO:0005737|GO:0008968 KEGG: 00540+5.3.1.28|MetaCyc: PWY-6478 THITH_02425 73054f6f313c32d5702ce736f87381de 204 Pfam PF13580 SIS domain 12 145 9.1E-32 T 13-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 THITH_00570 714870953dbe1ded059736d113343b30 486 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 163 187 1.7E-11 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_00570 714870953dbe1ded059736d113343b30 486 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 380 406 1.7E-11 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_00570 714870953dbe1ded059736d113343b30 486 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 328 347 1.7E-11 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_00570 714870953dbe1ded059736d113343b30 486 Pfam PF00361 Proton-conducting membrane transporter 127 423 1.0E-52 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_04080 8c89bac2016d411e8529728f060c9207 149 Gene3D G3DSA:3.40.630.30 2 142 1.8E-39 T 13-10-2018 THITH_04080 8c89bac2016d411e8529728f060c9207 149 SUPERFAMILY SSF55729 2 143 3.88E-39 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_04080 8c89bac2016d411e8529728f060c9207 149 Pfam PF13673 Acetyltransferase (GNAT) domain 23 140 4.5E-21 T 13-10-2018 IPR000182 GNAT domain THITH_07240 c9afbeada30c1fe0c497e62281f79dc2 406 Gene3D G3DSA:3.40.50.300 26 186 4.3E-12 T 13-10-2018 THITH_07240 c9afbeada30c1fe0c497e62281f79dc2 406 Pfam PF05128 Domain of unknown function (DUF697) 272 384 2.3E-6 T 13-10-2018 IPR021147 Protein of unknown function DUF697 THITH_07240 c9afbeada30c1fe0c497e62281f79dc2 406 SUPERFAMILY SSF52540 36 157 1.6E-13 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_09545 8b1235ec2f259bbadf58d784072b0502 275 Hamap MF_01805 Segregation and condensation protein A [scpA]. 40 270 21.431 T 13-10-2018 IPR003768 Segregation and condensation protein A THITH_09545 8b1235ec2f259bbadf58d784072b0502 275 Pfam PF02616 Segregation and condensation protein ScpA 57 266 4.6E-26 T 13-10-2018 IPR003768 Segregation and condensation protein A THITH_02290 a2395275d3bedf5a0053dc74aeb240a2 357 Pfam PF06580 Histidine kinase 158 232 2.7E-21 T 13-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 THITH_02290 a2395275d3bedf5a0053dc74aeb240a2 357 SUPERFAMILY SSF55874 209 292 3.72E-6 T 13-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily THITH_05890 aecf8430b3e37d23996babfae2b04494 76 SUPERFAMILY SSF47598 1 45 6.67E-5 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 THITH_12930 6b1b23364746fe6bdd5c7d558d1f4a15 508 Pfam PF00361 Proton-conducting membrane transporter 133 431 1.6E-73 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12930 6b1b23364746fe6bdd5c7d558d1f4a15 508 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 8 498 1.7E-181 T 13-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12930 6b1b23364746fe6bdd5c7d558d1f4a15 508 Pfam PF01059 NADH-ubiquinone oxidoreductase chain 4, amino terminus 71 126 1.2E-5 T 13-10-2018 IPR000260 NADH:ubiquinone oxidoreductase chain 4, N-terminal GO:0006120|GO:0055114 KEGG: 00190+1.6.5.3|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-5083|MetaCyc: PWY-6692|Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12930 6b1b23364746fe6bdd5c7d558d1f4a15 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 168 192 3.2E-40 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12930 6b1b23364746fe6bdd5c7d558d1f4a15 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 390 416 3.2E-40 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12930 6b1b23364746fe6bdd5c7d558d1f4a15 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 238 262 3.2E-40 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_12930 6b1b23364746fe6bdd5c7d558d1f4a15 508 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 138 157 3.2E-40 T 13-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_00405 bf815df39513106fe7c8bcb3f2aaa4c8 335 Gene3D G3DSA:3.90.25.10 180 328 5.9E-95 T 13-10-2018 THITH_00405 bf815df39513106fe7c8bcb3f2aaa4c8 335 PRINTS PR01713 Nucleotide sugar epimerase signature 295 312 5.5E-29 T 13-10-2018 THITH_00405 bf815df39513106fe7c8bcb3f2aaa4c8 335 PRINTS PR01713 Nucleotide sugar epimerase signature 29 45 5.5E-29 T 13-10-2018 THITH_00405 bf815df39513106fe7c8bcb3f2aaa4c8 335 PRINTS PR01713 Nucleotide sugar epimerase signature 216 231 5.5E-29 T 13-10-2018 THITH_00405 bf815df39513106fe7c8bcb3f2aaa4c8 335 PRINTS PR01713 Nucleotide sugar epimerase signature 256 271 5.5E-29 T 13-10-2018 THITH_00405 bf815df39513106fe7c8bcb3f2aaa4c8 335 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 239 7.5E-58 T 13-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 THITH_00405 bf815df39513106fe7c8bcb3f2aaa4c8 335 Gene3D G3DSA:3.40.50.720 4 316 5.9E-95 T 13-10-2018 THITH_00405 bf815df39513106fe7c8bcb3f2aaa4c8 335 SUPERFAMILY SSF51735 2 333 2.01E-91 T 13-10-2018 IPR036291 NAD(P)-binding domain superfamily THITH_05590 93c75f0cdd1192d508bc63c29e35560f 75 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 51 1.1E-7 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THITH_05590 93c75f0cdd1192d508bc63c29e35560f 75 SUPERFAMILY SSF143120 1 47 3.14E-6 T 13-10-2018 IPR036165 YefM-like superfamily THITH_07995 9c39b4cf80647609aa39aa3fbdb7c09f 295 SUPERFAMILY SSF53448 8 275 1.33E-61 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_07995 9c39b4cf80647609aa39aa3fbdb7c09f 295 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 8 271 5.6E-111 T 13-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 THITH_07995 9c39b4cf80647609aa39aa3fbdb7c09f 295 Gene3D G3DSA:3.90.550.10 1 294 9.6E-87 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_07995 9c39b4cf80647609aa39aa3fbdb7c09f 295 Pfam PF00483 Nucleotidyl transferase 16 271 7.2E-27 T 13-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 THITH_04435 706f42e09f0f8f7ef1ea10e02598300d 141 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 7 131 3.8E-34 T 13-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein THITH_04985 1a0e83cac2e8b95ab3b6fd9a41277971 118 Pfam PF01934 Protein of unknown function DUF86 14 108 7.6E-23 T 13-10-2018 IPR008201 Protein of unknown function DUF86 THITH_00565 d3d3559ae417c1c1ddf17bf2d7f7ad81 498 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 106 126 1.5E-15 T 13-10-2018 THITH_00565 d3d3559ae417c1c1ddf17bf2d7f7ad81 498 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 241 267 1.5E-15 T 13-10-2018 THITH_00565 d3d3559ae417c1c1ddf17bf2d7f7ad81 498 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 219 240 1.5E-15 T 13-10-2018 THITH_00565 d3d3559ae417c1c1ddf17bf2d7f7ad81 498 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 78 103 1.5E-15 T 13-10-2018 THITH_00565 d3d3559ae417c1c1ddf17bf2d7f7ad81 498 Pfam PF00361 Proton-conducting membrane transporter 129 422 3.3E-56 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_17295 48403f2a0654b92561a0de3eb9b6821c 315 Gene3D G3DSA:3.30.450.20 1 136 1.6E-11 T 13-10-2018 THITH_17295 48403f2a0654b92561a0de3eb9b6821c 315 SUPERFAMILY SSF103190 20 142 3.14E-13 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily THITH_16100 0fcfdeb9cff937160a23cf7c2e8b425d 486 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 70 232 2.3E-9 T 13-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like THITH_09875 386560c95aabebe25adf27eebe72e33d 507 Gene3D G3DSA:3.40.50.150 1 216 1.3E-49 T 13-10-2018 THITH_09875 386560c95aabebe25adf27eebe72e33d 507 Pfam PF08241 Methyltransferase domain 44 137 1.6E-12 T 13-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 THITH_09875 386560c95aabebe25adf27eebe72e33d 507 SUPERFAMILY SSF53335 4 192 3.16E-27 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_05210 043deee422abf1b6fbec1cbc1e5f3ccb 188 Pfam PF01930 Domain of unknown function DUF83 30 185 7.2E-21 T 13-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 THITH_11175 69cebd3c83331533bf143b33b2c12cb6 377 Pfam PF14319 Transposase zinc-binding domain 15 111 2.0E-33 T 13-10-2018 IPR026889 Transposase zinc-binding domain THITH_11175 69cebd3c83331533bf143b33b2c12cb6 377 Pfam PF04986 Putative transposase 137 317 2.1E-57 T 13-10-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THITH_12475 11a209f463ac703f9561648b9fa02325 283 Pfam PF09955 Predicted integral membrane protein (DUF2189) 81 209 1.8E-28 T 13-10-2018 IPR018692 Predicted integral membrane protein DUF2189 THITH_13270 b97ab21e861c8086f42e636236c4e57e 415 SUPERFAMILY SSF50939 49 354 1.61E-19 T 13-10-2018 IPR036278 Sialidase superfamily KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18|Reactome: R-HSA-1660662|Reactome: R-HSA-4085001 THITH_09080 405ab051e4de70d4c0bb3f1daaa76f9c 131 Pfam PF07681 DoxX 11 90 3.1E-14 T 13-10-2018 IPR032808 DoxX family THITH_08900 cf840e66cb70d6c8b938661bcb75283a 82 Pfam PF09851 Short C-terminal domain 50 75 3.0E-11 T 13-10-2018 IPR018649 SHOCT domain THITH_08765 3a81b08c3f93e5bae546854de62b8773 107 Gene3D G3DSA:3.30.1390.10 5 107 4.2E-44 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like THITH_08765 3a81b08c3f93e5bae546854de62b8773 107 SUPERFAMILY SSF54736 22 106 2.14E-32 T 13-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like THITH_08765 3a81b08c3f93e5bae546854de62b8773 107 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 15 102 29.005 T 13-10-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS THITH_08765 3a81b08c3f93e5bae546854de62b8773 107 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 24 103 2.2E-34 T 13-10-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 THITH_06680 fe37aa936222b8b84d2e5034bc5324a5 238 SUPERFAMILY SSF58104 113 224 6.54E-5 T 13-10-2018 THITH_06680 fe37aa936222b8b84d2e5034bc5324a5 238 Gene3D G3DSA:1.20.5.170 118 229 3.5E-6 T 13-10-2018 THITH_02040 54ee86448e663ac8586a885d2921bc4a 531 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 70 229 5.0E-19 T 13-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like THITH_12495 55368fc542c80841ea9540579ffd722b 300 Pfam PF00535 Glycosyl transferase family 2 2 100 2.0E-16 T 13-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 THITH_12495 55368fc542c80841ea9540579ffd722b 300 Gene3D G3DSA:3.90.550.10 1 204 9.6E-35 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_12495 55368fc542c80841ea9540579ffd722b 300 SUPERFAMILY SSF53448 2 194 1.08E-37 T 13-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases THITH_08290 af38ee48c4d3a82af608dcd2e0d0e412 142 Pfam PF09722 Protein of unknown function (DUF2384) 90 139 4.0E-15 T 13-10-2018 IPR024467 Domain of unknown function DUF2384 THITH_02165 f19428eb3baf545c7feaa205150bd47f 144 Gene3D G3DSA:1.20.120.580 5 130 6.0E-7 T 13-10-2018 IPR037038 Bsu32300-like superfamily THITH_02165 f19428eb3baf545c7feaa205150bd47f 144 Pfam PF01934 Protein of unknown function DUF86 30 121 5.9E-18 T 13-10-2018 IPR008201 Protein of unknown function DUF86 THITH_07315 f35046cd4d302e5095d27f1edf0df01c 162 Pfam PF01521 Iron-sulphur cluster biosynthesis 58 157 9.4E-16 T 13-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 THITH_07315 f35046cd4d302e5095d27f1edf0df01c 162 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 57 160 2.4E-28 T 13-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 THITH_07315 f35046cd4d302e5095d27f1edf0df01c 162 SUPERFAMILY SSF89360 56 150 1.02E-22 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 THITH_07315 f35046cd4d302e5095d27f1edf0df01c 162 Gene3D G3DSA:2.60.300.12 55 161 1.7E-31 T 13-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 THITH_16270 5555e5688153bd7a5d896b84adfe475f 163 Pfam PF03843 Outer membrane lipoprotein Slp family 18 149 1.8E-29 T 13-10-2018 IPR004658 Outer membrane lipoprotein Slp GO:0019867 THITH_00310 bd50fef63ed4bafbf8d53ef43f60a20e 114 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 44 6.3E-8 T 13-10-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM THITH_00310 bd50fef63ed4bafbf8d53ef43f60a20e 114 SUPERFAMILY SSF143120 1 48 4.84E-8 T 13-10-2018 IPR036165 YefM-like superfamily THITH_00310 bd50fef63ed4bafbf8d53ef43f60a20e 114 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 4 47 1.6E-5 T 13-10-2018 THITH_00310 bd50fef63ed4bafbf8d53ef43f60a20e 114 Pfam PF03683 Uncharacterised protein family (UPF0175) 33 106 8.8E-15 T 13-10-2018 IPR005368 Uncharacterised protein family UPF0175 THITH_06400 b6a26237e0d8d89aa65f8a73f58c50cd 242 Pfam PF09694 Bacterial protein of unknown function (Gcw_chp) 27 218 3.0E-33 T 13-10-2018 IPR010239 Conserved hypothetical protein CHP02001 THITH_06400 b6a26237e0d8d89aa65f8a73f58c50cd 242 TIGRFAM TIGR02001 gcw_chp: conserved hypothetical protein 1 242 1.1E-56 T 13-10-2018 IPR010239 Conserved hypothetical protein CHP02001 THITH_11300 dde3c44725e83a4af5564d03bec25aa5 120 Pfam PF07784 Protein of unknown function (DUF1622) 26 105 7.6E-23 T 13-10-2018 IPR012427 Protein of unknown function DUF1622 THITH_03800 53049a820302eb1ddd6c416144adbcda 142 Pfam PF06295 Protein of unknown function (DUF1043) 16 104 9.7E-19 T 13-10-2018 IPR009386 Protein of unknown function DUF1043 THITH_16405 3fd65e330723525e5e7ec25a765e3575 127 ProDom PD075772 YGBA ECS3588 CYTOPLASMIC UVRA STM2860 AMIDOPHOSPHORIBOSYLTRANSFERASE VVA0912 SO0324 VPA0976 CPE0229 14 106 3.0E-27 T 13-10-2018 IPR020483 Uncharacterised protein family YgbA THITH_16405 3fd65e330723525e5e7ec25a765e3575 127 Pfam PF11756 Nitrous oxide-stimulated promoter 10 113 3.2E-40 T 13-10-2018 IPR020483 Uncharacterised protein family YgbA THITH_15245 e497a81d6196f705913320b145a924da 229 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 9 210 5.6E-40 T 13-10-2018 IPR039447 Urease accessory protein UreH-like, transmembrane domain THITH_00670 ddf0232eaa976ded1a4ab5477730fbe1 554 SUPERFAMILY SSF48208 216 417 1.22E-19 T 13-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 THITH_01395 f3cdd293a833ea44d7aa76566faff3ec 201 Gene3D G3DSA:3.10.580.10 31 182 1.8E-12 T 13-10-2018 THITH_01395 f3cdd293a833ea44d7aa76566faff3ec 201 Pfam PF00571 CBS domain 43 90 9.4E-8 T 13-10-2018 IPR000644 CBS domain THITH_01395 f3cdd293a833ea44d7aa76566faff3ec 201 SUPERFAMILY SSF54631 42 173 1.08E-11 T 13-10-2018 THITH_01395 f3cdd293a833ea44d7aa76566faff3ec 201 SMART SM00116 48 96 6.0E-5 T 13-10-2018 IPR000644 CBS domain THITH_08850 3c3c1cb50f9373ed9d54fcf5772a9d8f 173 SUPERFAMILY SSF52540 6 168 1.13E-14 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_08850 3c3c1cb50f9373ed9d54fcf5772a9d8f 173 Gene3D G3DSA:3.40.50.300 1 172 1.0E-27 T 13-10-2018 THITH_08850 3c3c1cb50f9373ed9d54fcf5772a9d8f 173 Pfam PF06414 Zeta toxin 5 160 3.8E-9 T 13-10-2018 IPR010488 Zeta toxin domain GO:0005524|GO:0016301 THITH_05460 1ac5ad60ff5ab990fb99249bb39ff396 316 SUPERFAMILY SSF103190 47 143 5.49E-11 T 13-10-2018 IPR029151 Periplasmic sensor-like domain superfamily THITH_05460 1ac5ad60ff5ab990fb99249bb39ff396 316 Gene3D G3DSA:3.30.450.20 36 138 5.0E-6 T 13-10-2018 THITH_11385 f6abc510bb238c6668f2d3d1eaa9cc3d 395 Gene3D G3DSA:3.40.50.1980 29 151 1.5E-30 T 13-10-2018 THITH_11385 f6abc510bb238c6668f2d3d1eaa9cc3d 395 Gene3D G3DSA:3.40.50.1980 194 279 3.4E-17 T 13-10-2018 THITH_11385 f6abc510bb238c6668f2d3d1eaa9cc3d 395 Pfam PF01297 Zinc-uptake complex component A periplasmic 30 387 1.4E-57 T 13-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 THITH_11385 f6abc510bb238c6668f2d3d1eaa9cc3d 395 SUPERFAMILY SSF53807 28 390 9.42E-55 T 13-10-2018 THITH_11385 f6abc510bb238c6668f2d3d1eaa9cc3d 395 Gene3D G3DSA:3.40.50.1980 280 392 2.0E-39 T 13-10-2018 THITH_00260 d2e6f48c034c34888bbb8292b3aa940e 112 SUPERFAMILY SSF50118 6 108 2.4E-5 T 13-10-2018 THITH_17405 ec39f60b8d658d9035b089ddae4107da 471 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 19 234 1.4E-7 T 13-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 THITH_17405 ec39f60b8d658d9035b089ddae4107da 471 Gene3D G3DSA:1.10.760.10 347 448 5.6E-7 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_17405 ec39f60b8d658d9035b089ddae4107da 471 SUPERFAMILY SSF46626 363 448 1.23E-10 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_07030 a9f98dcbbf04737a0a9b3552d32d7675 50 Pfam PF11295 Protein of unknown function (DUF3096) 9 44 5.8E-20 T 13-10-2018 IPR021446 Protein of unknown function DUF3096 THITH_04925 65994a7895cb80a0409bdbe8e90fbfac 433 Pfam PF01565 FAD binding domain 30 143 5.6E-18 T 13-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 THITH_04925 65994a7895cb80a0409bdbe8e90fbfac 433 Gene3D G3DSA:3.30.465.10 62 189 1.2E-20 T 13-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 THITH_04925 65994a7895cb80a0409bdbe8e90fbfac 433 SUPERFAMILY SSF56176 30 175 7.94E-30 T 13-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 THITH_07885 bbb78ffbe1719897c8420dcc85621065 69 Pfam PF11127 Protein of unknown function (DUF2892) 6 65 4.3E-22 T 13-10-2018 IPR021309 Protein of unknown function DUF2892 THITH_15690 de175742894eb4fdd580f5300860f630 221 Pfam PF13511 Domain of unknown function (DUF4124) 17 52 2.9E-11 T 13-10-2018 IPR025392 Domain of unknown function DUF4124 THITH_09860 2053e4c2b8048e7cdea9b28c43adb768 788 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 190 297 1.8E-9 T 13-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like THITH_10180 10f8626492e359f5d389bcff44a48536 288 SUPERFAMILY SSF158544 97 178 1.46E-7 T 13-10-2018 IPR038072 GspK, central domain superfamily THITH_10180 10f8626492e359f5d389bcff44a48536 288 Pfam PF03934 Type II secretion system (T2SS), protein K 114 259 1.0E-7 T 13-10-2018 IPR005628 General secretion pathway protein K GO:0009306|GO:0016021 THITH_12360 9aea7133e814610590e91b6f3077a148 683 Pfam PF12288 Carboxysome shell peptide mid-region 81 496 1.6E-166 T 13-10-2018 IPR020990 Carboxysome shell protein THITH_12285 51c00e4220236654f15e40d0a7f2c0c8 164 SUPERFAMILY SSF103247 35 161 6.67E-13 T 13-10-2018 IPR035923 TT1751-like domain superfamily THITH_12285 51c00e4220236654f15e40d0a7f2c0c8 164 Pfam PF03625 Domain of unknown function DUF302 90 134 7.1E-7 T 13-10-2018 IPR005180 Domain of unknown function DUF302 THITH_02775 c7d42ab0376099c4d52e2f800067c007 249 Pfam PF11306 Protein of unknown function (DUF3108) 15 234 2.8E-32 T 13-10-2018 IPR021457 Protein of unknown function DUF3108 THITH_10030 b5fcb742d80b6af3b7430c82f1bfae7b 60 Pfam PF13396 Phospholipase_D-nuclease N-terminal 14 56 1.1E-12 T 13-10-2018 IPR027379 Cardiolipin synthase N-terminal THITH_12940 ab6b3724391a57f51892f4a8a45ff6ed 101 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 2 101 20.566 T 13-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 THITH_12940 ab6b3724391a57f51892f4a8a45ff6ed 101 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 7 96 1.5E-23 T 13-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like THITH_13925 94648e0ff4668753d6b7b28716cc55d9 247 Pfam PF01618 MotA/TolQ/ExbB proton channel family 103 207 2.0E-32 T 13-10-2018 IPR002898 MotA/TolQ/ExbB proton channel THITH_04525 24bd515b61298811faede6f55c7e4dd2 301 Pfam PF02535 ZIP Zinc transporter 158 296 6.8E-21 T 13-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 THITH_11870 5547ed1cdd69237b0b2b6104a6a34c3f 224 Pfam PF06226 Protein of unknown function (DUF1007) 19 222 4.5E-54 T 13-10-2018 IPR010412 Protein of unknown function DUF1007 THITH_01960 d690c89eaab11eb090698ecad893c040 344 Pfam PF14321 Domain of unknown function (DUF4382) 33 199 3.8E-25 T 13-10-2018 IPR025491 Domain of unknown function DUF4382 THITH_05755 c1171bbf391b03e5affe18b17d1ec440 120 TIGRFAM TIGR04256 GxxExxY: GxxExxY protein 5 119 4.7E-43 T 13-10-2018 IPR026350 GxxExxY protein THITH_05755 c1171bbf391b03e5affe18b17d1ec440 120 Pfam PF13366 PD-(D/E)XK nuclease superfamily 5 117 4.5E-39 T 13-10-2018 IPR026350 GxxExxY protein THITH_15895 5d1de3cb13110edb07624c64c3c8cf08 221 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 9 208 3.1E-9 T 13-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 THITH_05485 27129a1cd1ce4c701759fff7ee0ec3c2 508 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 214 477 6.8E-57 T 13-10-2018 IPR003846 Uncharacterised protein family UPF0061 THITH_05485 27129a1cd1ce4c701759fff7ee0ec3c2 508 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 4 185 1.6E-49 T 13-10-2018 IPR003846 Uncharacterised protein family UPF0061 THITH_05485 27129a1cd1ce4c701759fff7ee0ec3c2 508 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 1 494 44.247 T 13-10-2018 IPR003846 Uncharacterised protein family UPF0061 THITH_10140 6c6933b036b04403501687faacc5db9d 263 Pfam PF01061 ABC-2 type transporter 9 223 8.1E-22 T 13-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 THITH_06375 1ceb92ec4c4d682a7a9bb8d1823014d7 205 Pfam PF07027 Protein of unknown function (DUF1318) 107 205 3.9E-22 T 13-10-2018 IPR008309 Uncharacterised conserved protein UCP025560 THITH_13335 5db41e31904e43cce97174f31c0c5be2 548 SUPERFAMILY SSF51004 202 521 1.39E-16 T 13-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily THITH_13335 5db41e31904e43cce97174f31c0c5be2 548 Gene3D G3DSA:2.130.10.10 354 537 6.0E-14 T 13-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 THITH_13335 5db41e31904e43cce97174f31c0c5be2 548 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 34 58 3.7E-4 T 13-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal THITH_00320 115684287148f7de88dea957cb5194f2 82 Pfam PF07362 Post-segregation antitoxin CcdA 12 82 7.3E-26 T 13-10-2018 IPR009956 Post-segregation antitoxin CcdA THITH_07220 da882ed54b4f2735e685c521e96ec67c 75 Pfam PF06250 Protein of unknown function (DUF1016) 13 52 2.7E-7 T 13-10-2018 IPR009362 Protein of unknown function DUF1016 THITH_16490 e11b70c2980bc1b920e6f8c8d80f741c 75 Pfam PF03597 Cytochrome oxidase maturation protein cbb3-type 2 45 2.1E-22 T 13-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type THITH_16490 e11b70c2980bc1b920e6f8c8d80f741c 75 TIGRFAM TIGR00847 ccoS: cytochrome oxidase maturation protein, cbb3-type 1 46 1.4E-16 T 13-10-2018 IPR004714 Cytochrome oxidase maturation protein cbb3-type THITH_06455 952406b005e1dc0d0d3375204082eb65 129 Pfam PF09523 Protein of unknown function (DUF2390) 2 85 7.9E-13 T 13-10-2018 IPR012659 Conserved hypothetical protein CHP02444 THITH_08840 4223d155b825572359368704b215c90a 147 Pfam PF13115 YtkA-like 66 132 9.3E-6 T 13-10-2018 IPR032693 YtkA-like domain THITH_08950 828802e0297f2b38aaf4348d2b1d9fd6 152 SUPERFAMILY SSF46626 55 147 6.76E-17 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_08950 828802e0297f2b38aaf4348d2b1d9fd6 152 Gene3D G3DSA:1.10.760.10 35 148 1.5E-13 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_08950 828802e0297f2b38aaf4348d2b1d9fd6 152 Pfam PF00034 Cytochrome c 64 145 2.0E-10 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_02030 9560d84de419e483ff16bdbdace6fe0f 315 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 19 295 1.1E-24 T 13-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD THITH_00030 62d4eb790aa6009b16da7ef8cf3f198b 305 ProSitePatterns PS00018 EF-hand calcium-binding domain. 215 227 - T 13-10-2018 IPR018247 EF-Hand 1, calcium-binding site THITH_06695 53764b8be0875c913dfb7d5427b78099 84 Pfam PF04226 Transglycosylase associated protein 35 83 6.0E-11 T 13-10-2018 IPR007341 Transglycosylase-associated protein GO:0016021 THITH_16110 15f67f5510e3801e7f5ee286bc73024d 125 Pfam PF11154 Protein of unknown function (DUF2934) 85 120 7.5E-13 T 13-10-2018 IPR021327 Protein of unknown function DUF2934 THITH_10265 b587498ae7857220168e40e4771c7823 233 Pfam PF13645 L,D-transpeptidase catalytic domain 40 207 1.9E-64 T 13-10-2018 IPR032676 Putative L,D-transpeptidase tautomerase THITH_04715 c3afa0f10544bd3dd80e97c2a96a4064 148 SUPERFAMILY SSF54197 4 80 9.74E-17 T 13-10-2018 IPR036265 HIT-like superfamily THITH_04715 c3afa0f10544bd3dd80e97c2a96a4064 148 Pfam PF01230 HIT domain 23 88 1.0E-7 T 13-10-2018 IPR001310 Histidine triad (HIT) protein THITH_04715 c3afa0f10544bd3dd80e97c2a96a4064 148 Gene3D G3DSA:3.30.428.10 1 107 5.3E-19 T 13-10-2018 IPR036265 HIT-like superfamily THITH_10985 b3eb953ea2be010b2a427e0059efd8fa 225 Pfam PF09335 SNARE associated Golgi protein 67 182 8.3E-23 T 13-10-2018 IPR032816 SNARE associated Golgi protein THITH_05990 2bd2c705bb9e1eed688a435634f790b5 113 Pfam PF02698 DUF218 domain 2 82 4.3E-12 T 13-10-2018 IPR003848 Domain of unknown function DUF218 THITH_12315 0c9df4066958a22c1e39c040d5f53639 335 Pfam PF05982 Na+-dependent bicarbonate transporter superfamily 10 329 1.1E-116 T 13-10-2018 IPR010293 Na+-dependent bicarbonate transporter superfamily THITH_05280 3082b68d2d5af6107a0a2ea03f5e983d 208 Pfam PF01169 Uncharacterized protein family UPF0016 6 80 3.1E-15 T 13-10-2018 IPR001727 Gdt1 family THITH_05280 3082b68d2d5af6107a0a2ea03f5e983d 208 Pfam PF01169 Uncharacterized protein family UPF0016 103 177 4.9E-14 T 13-10-2018 IPR001727 Gdt1 family THITH_07105 ada253dcbb27b820c7bdf7512bdf68a8 220 Pfam PF05875 Ceramidase 12 201 1.4E-10 T 13-10-2018 IPR008901 Ceramidase GO:0006672|GO:0016021|GO:0016811 Reactome: R-HSA-1660661 THITH_17300 88bc4d6a124577c80c1836ec5c94a385 70 Pfam PF09834 Predicted membrane protein (DUF2061) 1 52 9.7E-22 T 13-10-2018 IPR018638 Domain of unknown function DUF2061, membrane THITH_04190 e177a3d475b66fc790c04d3125a1adc9 159 Pfam PF04306 Protein of unknown function (DUF456) 21 155 7.2E-36 T 13-10-2018 IPR007403 Protein of unknown function DUF456 THITH_02880 159a95c5dbf4c4a073e6897d1641f519 205 SUPERFAMILY SSF53474 5 186 7.56E-22 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_02880 159a95c5dbf4c4a073e6897d1641f519 205 Pfam PF12697 Alpha/beta hydrolase family 5 143 7.1E-9 T 13-10-2018 IPR000073 Alpha/beta hydrolase fold-1 THITH_06820 c6e090c5c7d49871dec462b5922b1db8 305 SMART SM00849 43 232 1.4E-25 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_06820 c6e090c5c7d49871dec462b5922b1db8 305 Pfam PF00753 Metallo-beta-lactamase superfamily 43 232 3.3E-21 T 13-10-2018 IPR001279 Metallo-beta-lactamase THITH_06820 c6e090c5c7d49871dec462b5922b1db8 305 SUPERFAMILY SSF56281 24 283 3.11E-51 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_06820 c6e090c5c7d49871dec462b5922b1db8 305 Gene3D G3DSA:3.60.15.10 16 257 7.4E-46 T 13-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like THITH_02365 efa8d5a5f70207618b45af05562dd7fb 129 Pfam PF12616 Protein of unknown function (DUF3775) 54 125 1.7E-22 T 13-10-2018 IPR022254 Protein of unknown function DUF3775 THITH_00815 c41bee5e75f04b63899ac5112a63b592 305 SUPERFAMILY SSF103247 54 146 6.28E-5 T 13-10-2018 IPR035923 TT1751-like domain superfamily THITH_03330 ba76b33bd14fd6e122ad33f4c415d87f 362 Pfam PF12902 Ferritin-like 16 244 1.4E-66 T 13-10-2018 THITH_03330 ba76b33bd14fd6e122ad33f4c415d87f 362 Gene3D G3DSA:1.20.1260.10 3 251 5.7E-60 T 13-10-2018 IPR012347 Ferritin-like THITH_03330 ba76b33bd14fd6e122ad33f4c415d87f 362 SUPERFAMILY SSF47240 11 91 4.48E-5 T 13-10-2018 IPR009078 Ferritin-like superfamily THITH_11240 20a7b6e69d6e10a568250f1c6c043f88 237 Pfam PF05598 Transposase domain (DUF772) 95 157 2.3E-13 T 13-10-2018 IPR008490 Transposase InsH, N-terminal THITH_16590 d91fc6bfcb57ac909d96c4deccde9b27 84 Gene3D G3DSA:1.10.1220.10 10 59 5.2E-22 T 13-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 THITH_16590 d91fc6bfcb57ac909d96c4deccde9b27 84 SUPERFAMILY SSF47598 2 69 4.89E-21 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 THITH_00505 d4b03e6bf64adc9e230b902654a6063f 219 SUPERFAMILY SSF53335 21 210 8.13E-30 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_00505 d4b03e6bf64adc9e230b902654a6063f 219 Gene3D G3DSA:3.40.50.150 9 218 6.0E-29 T 13-10-2018 THITH_00505 d4b03e6bf64adc9e230b902654a6063f 219 Pfam PF13649 Methyltransferase domain 47 129 6.5E-13 T 13-10-2018 THITH_09555 c2f410dd52960535de52761cd8f025db 451 Pfam PF06097 Bacterial protein of unknown function (DUF945) 3 434 3.9E-41 T 13-10-2018 IPR010352 Protein of unknown function DUF945 THITH_00600 56a58e54afe940419f6b2c87baa7ba25 115 Pfam PF01899 Na+/H+ ion antiporter subunit 3 88 8.6E-19 T 13-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 THITH_04485 cdd4455c7ea07abc37f4ddd803810d94 443 Gene3D G3DSA:1.10.3720.10 228 441 1.8E-10 T 13-10-2018 IPR035906 MetI-like superfamily THITH_04485 cdd4455c7ea07abc37f4ddd803810d94 443 SUPERFAMILY SSF161098 233 420 7.19E-12 T 13-10-2018 IPR035906 MetI-like superfamily THITH_04485 cdd4455c7ea07abc37f4ddd803810d94 443 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 258 441 8.6E-16 T 13-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 THITH_08045 887b45ff0a52123c8d6252fe4b473065 131 Pfam PF17228 Sulphur globule protein 44 128 3.1E-8 T 13-10-2018 IPR035173 Sulphur globule protein THITH_00585 04e23db44a594968064dce204a808d3a 90 Pfam PF13244 Domain of unknown function (DUF4040) 12 77 2.3E-20 T 13-10-2018 IPR025383 Domain of unknown function DUF4040 THITH_04150 baeb1b158910644d5c790235a88beeee 142 Pfam PF01899 Na+/H+ ion antiporter subunit 1 118 1.7E-21 T 13-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 THITH_06505 6298a9882abe68b79efea1a191d1cd01 243 SUPERFAMILY SSF53335 37 187 2.57E-16 T 13-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase THITH_06505 6298a9882abe68b79efea1a191d1cd01 243 Pfam PF05050 Methyltransferase FkbM domain 19 181 5.0E-12 T 13-10-2018 IPR006342 Methyltransferase FkbM THITH_06505 6298a9882abe68b79efea1a191d1cd01 243 Gene3D G3DSA:3.40.50.150 6 193 1.5E-13 T 13-10-2018 THITH_08415 d20043c1585a265a46e75b70886b0bc2 150 SUPERFAMILY SSF46626 26 146 6.72E-19 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_08415 d20043c1585a265a46e75b70886b0bc2 150 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 50 132 4.1E-6 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_08415 d20043c1585a265a46e75b70886b0bc2 150 Gene3D G3DSA:1.10.760.10 1 150 2.1E-38 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_02870 724e4ec70140989c00ecc620f1f6db2a 217 Pfam PF04367 Protein of unknown function (DUF502) 60 165 3.1E-38 T 13-10-2018 IPR007462 Protein of unknown function DUF502 THITH_00575 2e13d2d645fdf3217f4aedb71aa8e0aa 98 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 11 94 8.0E-19 T 13-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like THITH_17175 9e27eb0e5fb3cb740dce6a040549546c 117 SUPERFAMILY SSF46626 10 117 1.83E-9 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_17175 9e27eb0e5fb3cb740dce6a040549546c 117 Pfam PF00034 Cytochrome c 32 117 1.0E-5 T 13-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 THITH_17175 9e27eb0e5fb3cb740dce6a040549546c 117 Gene3D G3DSA:1.10.760.10 31 116 1.9E-9 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_00750 e22fa644394baf2be2eeca141a73c5c0 157 Pfam PF11697 Protein of unknown function (DUF3293) 55 127 3.9E-16 T 13-10-2018 IPR021710 Protein of unknown function DUF3293 THITH_01890 c896a2e3391110c65fea51968dc38a93 289 SUPERFAMILY SSF140931 86 279 7.19E-35 T 13-10-2018 IPR036597 Fido-like domain superfamily THITH_01890 c896a2e3391110c65fea51968dc38a93 289 Gene3D G3DSA:1.10.3290.10 20 279 4.9E-73 T 13-10-2018 IPR036597 Fido-like domain superfamily THITH_01890 c896a2e3391110c65fea51968dc38a93 289 Pfam PF02661 Fic/DOC family 112 226 4.6E-19 T 13-10-2018 IPR003812 Fido domain THITH_08345 dab455c951ce2d8503ee515cda1d48a9 310 Pfam PF08239 Bacterial SH3 domain 12 68 3.2E-6 T 13-10-2018 IPR003646 SH3-like domain, bacterial-type THITH_08345 dab455c951ce2d8503ee515cda1d48a9 310 Gene3D G3DSA:2.30.30.40 8 73 1.1E-5 T 13-10-2018 THITH_14185 2ebc00da2eadd1d10fd4b138f2e47df9 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 2.3E-23 T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14185 2ebc00da2eadd1d10fd4b138f2e47df9 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.355 T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14185 2ebc00da2eadd1d10fd4b138f2e47df9 37 Pfam PF00444 Ribosomal protein L36 1 37 5.1E-19 T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14185 2ebc00da2eadd1d10fd4b138f2e47df9 37 SUPERFAMILY SSF57840 1 37 6.02E-17 T 13-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14185 2ebc00da2eadd1d10fd4b138f2e47df9 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 13-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 THITH_14185 2ebc00da2eadd1d10fd4b138f2e47df9 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 4.0E-8 T 13-10-2018 THITH_01300 87159337e3002402f5016515f38cd600 283 SUPERFAMILY SSF52540 13 224 3.74E-8 T 13-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase THITH_06610 1a46a8eea8279ddd25e823fab84c6c84 74 Pfam PF04102 SlyX 10 74 2.9E-17 T 13-10-2018 IPR007236 SlyX THITH_07670 63e8eb9bae7b63a38d15369641ec3a5b 168 Pfam PF02620 Uncharacterized ACR, COG1399 59 164 2.0E-11 T 13-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD THITH_04145 c275f73c6101b87e73e2c8f74ee7029b 102 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 30 77 3.5E-9 T 13-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 THITH_04300 9d4484d3f58f36f8d3891b987c0523ce 84 Gene3D G3DSA:1.10.1200.10 3 75 2.9E-14 T 13-10-2018 IPR036736 ACP-like superfamily THITH_04300 9d4484d3f58f36f8d3891b987c0523ce 84 Pfam PF00550 Phosphopantetheine attachment site 8 72 4.3E-9 T 13-10-2018 IPR009081 Phosphopantetheine binding ACP domain THITH_04300 9d4484d3f58f36f8d3891b987c0523ce 84 SUPERFAMILY SSF47336 1 79 1.83E-13 T 13-10-2018 IPR036736 ACP-like superfamily THITH_11330 44c14e8333d06580835756b855f0287b 151 Pfam PF05425 Copper resistance protein D 46 146 1.4E-14 T 13-10-2018 IPR008457 Copper resistance protein D GO:0016021 THITH_16980 4a0100013d3c0c05db9933e02beb209e 127 Pfam PF03899 ATP synthase I chain 14 107 2.3E-8 T 13-10-2018 IPR005598 ATP synthase protein I THITH_01920 ecb08b7dda9e148f1269bccbb80190a0 178 Pfam PF07670 Nucleoside recognition 8 101 1.6E-17 T 13-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 THITH_06055 2cb2316523194dd82ac8f6fa24f6051e 99 Pfam PF04365 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system 7 84 9.8E-18 T 13-10-2018 IPR007460 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system THITH_06055 2cb2316523194dd82ac8f6fa24f6051e 99 Gene3D G3DSA:3.10.450.530 1 86 1.0E-23 T 13-10-2018 IPR038573 Ribonuclease toxin BrnT superfamily THITH_00595 4cae3cdf87b5b624c22cd1377340f253 94 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 30 78 1.2E-11 T 13-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 THITH_13355 c830a02db025b0ec2361141f28313d94 208 Pfam PF01914 MarC family integral membrane protein 5 202 5.9E-49 T 13-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 THITH_13355 c830a02db025b0ec2361141f28313d94 208 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 3 201 9.2E-48 T 13-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 THITH_10170 1f2d31034412f9e531e95310a197fceb 180 Pfam PF10741 Type II secretion system (T2SS), protein M subtype b 80 174 2.3E-8 T 13-10-2018 IPR034756 Type II secretion system (T2SS), protein M subtype b THITH_05570 2d844879d00a6e5745cd94b8d7e96f32 345 Pfam PF00953 Glycosyl transferase family 4 54 214 5.7E-31 T 13-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 THITH_00390 9d8659bbd70de62ba0363b2627bb64c4 73 Pfam PF11455 Protein of unknown function (DUF3018) 6 71 4.8E-27 T 13-10-2018 IPR021558 Protein of unknown function DUF3018 THITH_02505 2f09d3bbc01c230f02e416157b54c86b 263 Pfam PF01925 Sulfite exporter TauE/SafE 8 260 6.4E-41 T 13-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 THITH_03170 0d54ee0365e202f2010291b44b9f5a28 1210 Pfam PF13699 Domain of unknown function (DUF4157) 218 295 5.9E-29 T 13-10-2018 IPR025295 Domain of unknown function DUF4157 THITH_10710 5a51bc9d0973de1d696978baee24c38d 335 Pfam PF01882 Protein of unknown function DUF58 227 300 1.6E-15 T 13-10-2018 IPR002881 Domain of unknown function DUF58 THITH_12665 af0ecfaf76624f1b1696d54638917359 336 Pfam PF01040 UbiA prenyltransferase family 56 306 1.5E-23 T 13-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 THITH_01945 02b97fe522c72e8debfed5326bbf9bfa 190 Gene3D G3DSA:1.20.120.1490 87 188 1.1E-15 T 13-10-2018 THITH_14890 df6583e6e56c9cc9af841988129675b2 191 Pfam PF05137 Fimbrial assembly protein (PilN) 100 176 2.4E-16 T 13-10-2018 IPR007813 Fimbrial assembly PilN THITH_00495 24f693d699728a4ded210c9eff2faf11 42 Pfam PF13627 Prokaryotic lipoprotein-attachment site 13 34 4.8E-9 T 13-10-2018 IPR032831 Prokaryotic lipoprotein-attachment site THITH_10040 87b3686f321149903304612aa16bfc23 280 SUPERFAMILY SSF55729 6 222 1.45E-5 T 13-10-2018 IPR016181 Acyl-CoA N-acyltransferase THITH_01135 8a8acb25399e69754a9a323050452807 84 Pfam PF07704 Rv0623-like transcription factor 1 83 6.1E-29 T 13-10-2018 IPR011660 Antitoxin VapB-like THITH_16735 81a8a3b9886800b8a0350dafd6fcc5af 347 Pfam PF03916 Polysulphide reductase, NrfD 41 296 1.0E-5 T 13-10-2018 IPR005614 NrfD family THITH_05530 a82da329a9904b0a0d6b131f07a514d5 86 Gene3D G3DSA:3.40.50.1820 1 84 3.8E-19 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_05530 a82da329a9904b0a0d6b131f07a514d5 86 Pfam PF08386 TAP-like protein 23 83 3.1E-8 T 13-10-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal THITH_05530 a82da329a9904b0a0d6b131f07a514d5 86 SUPERFAMILY SSF53474 10 84 6.93E-19 T 13-10-2018 IPR029058 Alpha/Beta hydrolase fold THITH_08490 16a6ea967af1affd346d381a1d27f128 380 Pfam PF14397 Sugar-transfer associated ATP-grasp 158 352 2.6E-16 T 13-10-2018 IPR039523 Alpha-L-glutamate ligase-related protein, ATP-grasp domain KEGG: 00270+6.3.2.2+6.3.2.3|KEGG: 00480+6.3.2.2+6.3.2.3|MetaCyc: PWY-6840|MetaCyc: PWY-7255 THITH_00635 3b09cba81b0b9435ded7a8c1fdc1b8bd 147 Pfam PF06695 Putative small multi-drug export protein 20 127 1.5E-12 T 13-10-2018 IPR009577 Putative small multi-drug export THITH_01855 a39bcd4e720aabfa4760831622f2d7cc 491 SUPERFAMILY SSF56300 4 332 8.68E-17 T 13-10-2018 THITH_01855 a39bcd4e720aabfa4760831622f2d7cc 491 Pfam PF00149 Calcineurin-like phosphoesterase 4 140 2.0E-8 T 13-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 THITH_05925 0273c6efe7ff54feb423d62edc1c745b 88 Pfam PF12441 CopG antitoxin of type II toxin-antitoxin system 7 83 1.9E-34 T 13-10-2018 IPR022148 CopG antitoxin THITH_07350 09c067f0c457c6995136061f9fc515b5 489 Pfam PF11067 Protein of unknown function (DUF2868) 168 458 1.3E-57 T 13-10-2018 IPR021296 Protein of unknown function DUF2868 THITH_13575 b6d30f180dd2edd545657362dc7c1f7e 127 Pfam PF12276 Protein of unknown function (DUF3617) 7 127 1.7E-18 T 13-10-2018 IPR022061 Protein of unknown function DUF3617 THITH_13945 4a9e40d5d50911750681cf6b110c5f9a 332 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 5 321 1.0E-94 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 THITH_13945 4a9e40d5d50911750681cf6b110c5f9a 332 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 5 247 3.0E-42 T 13-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 THITH_05575 3b7749cfaa15d7d0922978a067d5c616 92 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 3 89 1.2E-15 T 13-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family THITH_05575 3b7749cfaa15d7d0922978a067d5c616 92 Gene3D G3DSA:3.30.2310.20 1 90 4.4E-23 T 13-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily THITH_12550 979969e58f0f22f057b9435e2ea9b6d4 517 Pfam PF04293 SpoVR like protein 17 454 4.4E-161 T 13-10-2018 IPR007390 Sporulation stage V, protein R THITH_07235 6bceb763284ccaa187d746eb31c02f3e 236 Gene3D G3DSA:3.30.2010.10 137 229 1.4E-13 T 13-10-2018 THITH_07235 6bceb763284ccaa187d746eb31c02f3e 236 Pfam PF01863 Protein of unknown function DUF45 24 228 1.2E-55 T 13-10-2018 IPR002725 Protein of unknown function DUF45 THITH_11875 e4b3750cc9cffc0805c3bb22ff063cfb 380 Pfam PF03824 High-affinity nickel-transport protein 88 368 1.7E-40 T 13-10-2018 IPR011541 Nickel/cobalt transporter, high-affinity GO:0015099|GO:0016021|GO:0035444|GO:0046872 THITH_04130 d3f8ef59cdf4884397db41a595125daf 102 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 4 93 9.2E-20 T 13-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like THITH_14090 ad000d4cebf09897367a1c6c6fb772f0 213 Pfam PF13441 YMGG-like Gly-zipper 29 69 4.0E-8 T 13-10-2018 IPR027367 YMGG-like Gly-zipper THITH_06435 422144a6cde85cdd6437a1737e8a6a0d 60 Pfam PF05545 Cbb3-type cytochrome oxidase component FixQ 5 45 1.0E-14 T 13-10-2018 IPR008621 Cbb3-type cytochrome oxidase component THITH_04580 e64adc03a0ba9748c1f6d8722aa1865a 153 Pfam PF03682 Uncharacterised protein family (UPF0158) 9 150 7.2E-9 T 13-10-2018 IPR005361 Uncharacterised protein family UPF0158 THITH_08245 4c0d7187e429c146d3d907e9ddbfa478 448 Pfam PF13281 Domain of unknown function (DUF4071) 84 426 3.2E-42 T 13-10-2018 IPR025136 Domain of unknown function DUF4071 THITH_13345 9b12586be1e61996c4270079506ef29d 389 Pfam PF05425 Copper resistance protein D 176 272 5.1E-17 T 13-10-2018 IPR008457 Copper resistance protein D GO:0016021 THITH_11245 02b4ca2104094cf6a441dc9fdceb0252 326 Pfam PF01609 Transposase DDE domain 11 253 2.4E-18 T 13-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 THITH_15170 c67516bba32569487f9bd13c8bb74885 59 Pfam PF04986 Putative transposase 17 56 4.9E-6 T 13-10-2018 IPR007069 Transposase, IS801/IS1294 GO:0003677|GO:0004803|GO:0006313 THITH_13530 d94973b8ce86422f5e5e5071a897e63c 173 Pfam PF06271 RDD family 13 156 6.3E-19 T 13-10-2018 IPR010432 RDD THITH_10175 7817563c868497f5f74f3409c8d89991 336 Pfam PF05137 Fimbrial assembly protein (PilN) 257 329 9.1E-10 T 13-10-2018 IPR007813 Fimbrial assembly PilN THITH_01830 4fd5ae7532b3c4c4eb66c0f3a1f4188b 434 Gene3D G3DSA:2.40.160.10 62 389 5.4E-7 T 13-10-2018 IPR023614 Porin domain superfamily THITH_01830 4fd5ae7532b3c4c4eb66c0f3a1f4188b 434 SUPERFAMILY SSF56935 87 412 2.84E-10 T 13-10-2018 THITH_05880 21e9bbcb1112f11a550e83e1b08514d2 132 Pfam PF02698 DUF218 domain 1 121 1.3E-17 T 13-10-2018 IPR003848 Domain of unknown function DUF218 THITH_09410 dd84462b4e2cc1226754d4d841608604 166 Pfam PF06853 Protein of unknown function (DUF1249) 31 148 5.4E-33 T 13-10-2018 IPR009659 Protein of unknown function DUF1249 THITH_08905 0a68a47eb7745a0e91e93eb0d1412202 210 Pfam PF09851 Short C-terminal domain 183 208 2.3E-7 T 13-10-2018 IPR018649 SHOCT domain THITH_06010 df6cc6ae7403dad0f3d2c696959624e7 333 Pfam PF02698 DUF218 domain 83 246 1.4E-23 T 13-10-2018 IPR003848 Domain of unknown function DUF218 THITH_03190 f9c938e8bdaa7d9e7ff081c2f4d4bde6 172 SUPERFAMILY SSF81593 56 151 8.63E-13 T 13-10-2018 THITH_07175 63416a079beda102e0e318d87307944f 504 Pfam PF07556 Protein of unknown function (DUF1538) 282 491 1.8E-68 T 13-10-2018 IPR011435 Protein of unknown function DUF1538 THITH_07175 63416a079beda102e0e318d87307944f 504 Pfam PF07556 Protein of unknown function (DUF1538) 21 231 1.1E-66 T 13-10-2018 IPR011435 Protein of unknown function DUF1538 THITH_05195 14dcd4219bbd3d4376a4ac29eafcb0c0 335 TIGRFAM TIGR03157 cas_Csc2: CRISPR type I-D/CYANO-associated protein Csc2 119 276 2.9E-12 T 13-10-2018 IPR017574 CRISPR-associated protein Csc2 THITH_05865 c264cc776bb6a60a83836075a6e4b8ae 257 Pfam PF02698 DUF218 domain 83 245 1.2E-21 T 13-10-2018 IPR003848 Domain of unknown function DUF218 THITH_03510 064b83211bbab28e36a4202ad490647c 62 Pfam PF09838 Uncharacterized protein conserved in bacteria (DUF2065) 5 60 8.3E-20 T 13-10-2018 IPR019201 Protein of unknown function DUF2065 THITH_15335 b3d20cc95ccd5cefe1dbbab88ab060dd 250 Pfam PF11906 Protein of unknown function (DUF3426) 109 247 1.6E-23 T 13-10-2018 IPR021834 Protein of unknown function DUF3426 THITH_16305 2a41ebfd9e250c663bf3f8db3f96d203 157 Pfam PF03703 Bacterial PH domain 74 148 7.1E-14 T 13-10-2018 IPR005182 Domain of unknown function DUF304 THITH_00400 130720e476f46614475c25fca3796ee3 572 Pfam PF00361 Proton-conducting membrane transporter 123 349 6.8E-28 T 13-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 THITH_15375 e994f1251ca81ca2a5504c2e2fecabe3 198 Pfam PF04367 Protein of unknown function (DUF502) 56 161 3.3E-28 T 13-10-2018 IPR007462 Protein of unknown function DUF502 THITH_11765 f54caec1061b19d518160c492ef895ca 145 Pfam PF10899 Putative abortive phage resistance protein AbiGi, antitoxin 2 104 4.3E-5 T 13-10-2018 IPR021223 Abortive phage resistance protein AbiGi THITH_00090 7c7dd0593475be2ae7260b544ea426ff 267 Pfam PF01203 Type II secretion system (T2SS), protein N 47 252 3.0E-37 T 13-10-2018 IPR022792 Type II secretion system, protein N THITH_04350 9a9a5566b880c492c4fda7f025cca249 140 Pfam PF08897 Domain of unknown function (DUF1841) 4 137 3.0E-56 T 13-10-2018 IPR014993 Protein of unknown function DUF1841 THITH_05935 b4af98970000d2da1ba0d7aa7a543d54 257 Pfam PF02698 DUF218 domain 83 246 2.1E-27 T 13-10-2018 IPR003848 Domain of unknown function DUF218 THITH_05535 6fbc4642270a6d46419853e3013ddefe 425 Pfam PF04932 O-Antigen ligase 218 359 1.6E-6 T 13-10-2018 IPR007016 O-antigen ligase-related THITH_04255 ea4806a6ffc4943237971f17c694f532 315 Pfam PF11376 Protein of unknown function (DUF3179) 10 231 2.5E-39 T 13-10-2018 IPR021516 Protein of unknown function DUF3179 THITH_04255 ea4806a6ffc4943237971f17c694f532 315 Pfam PF11376 Protein of unknown function (DUF3179) 225 301 1.1E-7 T 13-10-2018 IPR021516 Protein of unknown function DUF3179 THITH_01815 2af75cba8b54633f2878652cec8b48a7 263 Pfam PF03618 Kinase/pyrophosphorylase 5 258 6.6E-67 T 13-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 THITH_04075 3d3016b9df954fa421df49079479ac8f 163 SUPERFAMILY SSF56024 16 105 3.14E-5 T 13-10-2018 THITH_08835 3d151a8514a3267311309446f49f34b2 259 Pfam PF09335 SNARE associated Golgi protein 98 214 1.3E-15 T 13-10-2018 IPR032816 SNARE associated Golgi protein THITH_08095 fc51c2e0f3094f4d290e49cd9f7607ed 393 Pfam PF05940 NnrS protein 18 391 1.4E-104 T 13-10-2018 IPR010266 NnrS THITH_15360 21f001bba1c4c1bf30698eaa9f9afd78 49 Pfam PF08085 Entericidin EcnA/B family 24 43 4.6E-11 T 13-10-2018 IPR012556 Entericidin A/B GO:0009636|GO:0016020 THITH_08885 e0043f19228852e19221bdc3e9eee771 76 SUPERFAMILY SSF46626 10 68 3.94E-5 T 13-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 THITH_14115 eef1465547ac8fcab4722abbc1faa842 178 Pfam PF07295 Zinc-ribbon containing domain 26 170 9.4E-48 T 13-10-2018 IPR009912 Zinc-ribbon containing domain THITH_10690 e5607dc768f63bf19053e64a77e20a0e 338 Pfam PF02470 MlaD protein 37 141 4.7E-9 T 13-10-2018 IPR003399 Mce/MlaD THITH_00335 1293d77628e89ab975a1709726b5334f 79 SUPERFAMILY SSF47598 3 47 8.89E-10 T 13-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 THITH_05525 6e3d3e9090e5b5e3b53dda7655784c85 133 Pfam PF04138 GtrA-like protein 10 123 2.9E-24 T 13-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 THITH_16380 27fa2aca1cc3f69f18e43b4a96c53273 201 Pfam PF06226 Protein of unknown function (DUF1007) 3 195 1.4E-51 T 13-10-2018 IPR010412 Protein of unknown function DUF1007 THITH_11100 ea4caef2f0bb19ac419bea7c2fee35d8 91 SUPERFAMILY SSF88723 1 89 5.56E-8 T 13-10-2018 IPR029060 PIN-like domain superfamily THITH_03075 957c269657707aa69b23c025dee7f8f3 195 Pfam PF14065 Protein of unknown function (DUF4255) 13 187 3.0E-28 T 13-10-2018 IPR025351 Protein of unknown function DUF4255