locus-tag	class	description
Tgr7_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Tgr7_0002	COG0592	DNA-directed DNA polymerase activity
Tgr7_0003	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Tgr7_0004	COG0187	DNA topoisomerase II activity
Tgr7_0005	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Tgr7_0006	COG0339	signal peptide processing
Tgr7_0007	COG0708	Exodeoxyribonuclease III
Tgr7_0008	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
Tgr7_0011	COG1942	4-Oxalocrotonate Tautomerase
Tgr7_0015	COG3123	guanosine phosphorylase activity
Tgr7_0020	COG1238	metal cluster binding
Tgr7_0022	COG2204	response regulator
Tgr7_0025	COG0543	2 iron, 2 sulfur cluster binding
Tgr7_0025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Tgr7_0028	COG1587	Uroporphyrinogen-III synthase
Tgr7_0029	COG0181	hydroxymethylbilane synthase activity
Tgr7_0032	COG2972	Histidine kinase
Tgr7_0032	COG0745	RESPONSE REGULATOR receiver
Tgr7_0033	COG0165	Argininosuccinate lyase
Tgr7_0034	COG5001	Diguanylate cyclase
Tgr7_0034	COG5002	protein histidine kinase activity
Tgr7_0035	COG0400	carboxylic ester hydrolase activity
Tgr7_0039	COG3852	Histidine kinase
Tgr7_0041	COG0019	diaminopimelate decarboxylase activity
Tgr7_0042	COG4106	trans-aconitate 2-methyltransferase activity
Tgr7_0045	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Tgr7_0047	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
Tgr7_0048	COG0714	Associated with various cellular activities
Tgr7_0052	COG2304	oxidoreductase activity
Tgr7_0056	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
Tgr7_0057	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
Tgr7_0059	COG2226	methyltransferase
Tgr7_0061	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Tgr7_0062	COG0425	Belongs to the sulfur carrier protein TusA family
Tgr7_0063	COG2391	methyltransferase activity
Tgr7_0074	COG2204	response regulator
Tgr7_0076	COG3706	GGDEF domain
Tgr7_0078	COG0508	dehydrogenase complex catalyzes the overall conversion of
Tgr7_0080	COG0210	DNA helicase
Tgr7_0082	COG2198	Histidine kinase
Tgr7_0082	COG2205	protein histidine kinase activity
Tgr7_0082	COG0784	Response regulator, receiver
Tgr7_0083	COG1024	Enoyl-CoA hydratase
Tgr7_0084	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Tgr7_0086	COG1611	Belongs to the LOG family
Tgr7_0088	COG0218	Necessary for normal cell division and for the maintenance of normal septation
Tgr7_0090	COG1333	cytochrome c biogenesis protein
Tgr7_0091	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Tgr7_0094	COG2203	Gaf domain
Tgr7_0094	COG3706	GGDEF domain
Tgr7_0094	COG4251	negative regulation of phosphorylation
Tgr7_0094	COG5001	Diguanylate cyclase
Tgr7_0098	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Tgr7_0100	COG2003	Belongs to the UPF0758 family
Tgr7_0102	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
Tgr7_0103	COG0756	dUTP diphosphatase activity
Tgr7_0104	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Tgr7_0108	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
Tgr7_0109	COG0708	Exodeoxyribonuclease III
Tgr7_0110	COG2211	Major facilitator Superfamily
Tgr7_0116	COG0408	coproporphyrinogen oxidase activity
Tgr7_0117	COG5001	Diguanylate cyclase
Tgr7_0117	COG5002	protein histidine kinase activity
Tgr7_0119	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
Tgr7_0120	COG2885	chlorophyll binding
Tgr7_0121	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Tgr7_0123	COG1335	isochorismatase
Tgr7_0125	COG0784	Response regulator, receiver
Tgr7_0125	COG5002	protein histidine kinase activity
Tgr7_0126	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
Tgr7_0128	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
Tgr7_0129	COG1040	competence protein
Tgr7_0131	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Tgr7_0133	COG0156	8-amino-7-oxononanoate synthase activity
Tgr7_0136	COG1649	PFAM Uncharacterised BCR, COG1649
Tgr7_0136	COG0726	polysaccharide deacetylase
Tgr7_0144	COG0697	spore germination
Tgr7_0152	COG3153	acetyltransferase
Tgr7_0156	COG1201	RNA secondary structure unwinding
Tgr7_0166	COG0745	RESPONSE REGULATOR receiver
Tgr7_0167	COG2205	protein histidine kinase activity
Tgr7_0171	COG5002	protein histidine kinase activity
Tgr7_0171	COG5001	Diguanylate cyclase
Tgr7_0172	COG1278	Cold shock
Tgr7_0174	COG2719	SpoVR family
Tgr7_0175	COG2718	Belongs to the UPF0229 family
Tgr7_0176	COG2766	serine protein kinase
Tgr7_0177	COG0438	transferase activity, transferring glycosyl groups
Tgr7_0181	COG1335	isochorismatase
Tgr7_0184	COG0540	Belongs to the ATCase OTCase family
Tgr7_0185	COG0367	asparagine synthase
Tgr7_0186	COG0668	transmembrane transport
Tgr7_0188	COG3360	Dodecin
Tgr7_0190	COG0009	L-threonylcarbamoyladenylate synthase
Tgr7_0192	COG2922	Belongs to the Smg family
Tgr7_0193	COG0758	DNA mediated transformation
Tgr7_0195	COG0242	peptide deformylase activity
Tgr7_0196	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Tgr7_0199	COG5000	phosphorelay sensor kinase activity
Tgr7_0200	COG2204	response regulator
Tgr7_0201	COG0569	domain protein
Tgr7_0202	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Tgr7_0207	COG0037	tRNA processing
Tgr7_0209	COG1490	D-aminoacyl-tRNA deacylase activity
Tgr7_0210	COG0004	ammonium transporteR
Tgr7_0212	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Tgr7_0213	COG0131	Imidazoleglycerol-phosphate dehydratase
Tgr7_0215	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Tgr7_0216	COG0107	imidazoleglycerol-phosphate synthase activity
Tgr7_0217	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Tgr7_0218	COG0140	phosphoribosyl-ATP diphosphatase activity
Tgr7_0219	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Tgr7_0220	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Tgr7_0222	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
Tgr7_0224	COG3031	protein transport across the cell outer membrane
Tgr7_0241	COG4772	TonB-dependent receptor
Tgr7_0245	COG5001	Diguanylate cyclase
Tgr7_0245	COG5002	protein histidine kinase activity
Tgr7_0250	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Tgr7_0251	COG2226	methyltransferase
Tgr7_0254	COG1643	Atp-dependent helicase
Tgr7_0258	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Tgr7_0259	COG1067	ATP-dependent peptidase activity
Tgr7_0261	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Tgr7_0263	COG0018	arginyl-trna synthetase
Tgr7_0265	COG1058	Belongs to the CinA family
Tgr7_0265	COG1546	Belongs to the CinA family
Tgr7_0266	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Tgr7_0268	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Tgr7_0269	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Tgr7_0270	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Tgr7_0272	COG2197	response regulator
Tgr7_0275	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
Tgr7_0279	COG1752	Esterase of the alpha-beta hydrolase superfamily
Tgr7_0281	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Tgr7_0282	COG0205	6-phosphofructokinase activity
Tgr7_0286	COG1741	Belongs to the pirin family
Tgr7_0287	COG0583	DNA-binding transcription factor activity
Tgr7_0288	COG1741	Belongs to the pirin family
Tgr7_0290	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Tgr7_0291	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
Tgr7_0298	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Tgr7_0299	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
Tgr7_0300	COG0405	Gamma-glutamyltransferase
Tgr7_0301	COG1309	transcriptional regulator
Tgr7_0305	COG0583	DNA-binding transcription factor activity
Tgr7_0306	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Tgr7_0310	COG4191	Histidine kinase
Tgr7_0313	COG3258	Cytochrome c
Tgr7_0318	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Tgr7_0319	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Tgr7_0322	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
Tgr7_0324	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Tgr7_0325	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Tgr7_0326	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Tgr7_0327	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Tgr7_0328	COG1028	Short-chain dehydrogenase reductase Sdr
Tgr7_0330	COG1968	undecaprenyl-diphosphatase activity
Tgr7_0331	COG0617	tRNA 3'-terminal CCA addition
Tgr7_0332	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Tgr7_0333	COG1012	belongs to the aldehyde dehydrogenase family
Tgr7_0334	COG0586	Pfam SNARE associated Golgi protein
Tgr7_0335	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Tgr7_0336	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Tgr7_0338	COG3302	dmso reductase anchor subunit
Tgr7_0339	COG0437	4 iron, 4 sulfur cluster binding
Tgr7_0340	COG0243	molybdopterin cofactor binding
Tgr7_0348	COG1047	Peptidyl-prolyl cis-trans
Tgr7_0353	COG2046	Belongs to the sulfate adenylyltransferase family
Tgr7_0354	COG0563	adenylate kinase activity
Tgr7_0355	COG0205	6-phosphofructokinase activity
Tgr7_0358	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
Tgr7_0359	COG0058	SHG alpha-glucan phosphorylase activity
Tgr7_0360	COG0151	Belongs to the GarS family
Tgr7_0361	COG0138	bifunctional purine biosynthesis protein purh
Tgr7_0365	COG2920	part of a sulfur-relay system
Tgr7_0366	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Tgr7_0368	COG0439	Biotin carboxylase
Tgr7_0369	COG0511	ligase activity, forming carbon-carbon bonds
Tgr7_0370	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Tgr7_0372	COG4232	protein-disulfide reductase activity
Tgr7_0373	COG1324	tolerance protein
Tgr7_0374	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Tgr7_0398	COG1555	photosystem II stabilization
Tgr7_0412	COG2842	Transposition protein
Tgr7_0417	COG4396	Host-nuclease inhibitor protein Gam
Tgr7_0434	COG2369	cell adhesion
Tgr7_0436	COG3039	Transposase
Tgr7_0438	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Tgr7_0439	COG0459	protein refolding
Tgr7_0443	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
Tgr7_0445	COG0840	transmembrane signaling receptor activity
Tgr7_0446	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Tgr7_0449	COG0189	ligase activity
Tgr7_0452	COG0189	ligase activity
Tgr7_0452	COG4067	protein conserved in archaea
Tgr7_0453	COG3842	ATPase activity
Tgr7_0454	COG1178	ABC-type Fe3 transport system permease component
Tgr7_0455	COG1840	ABC-type Fe3 transport system, periplasmic component
Tgr7_0458	COG0515	serine threonine protein kinase
Tgr7_0458	COG2815	serine threonine protein kinase
Tgr7_0462	COG1595	DNA-templated transcription, initiation
Tgr7_0463	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Tgr7_0468	COG2226	methyltransferase
Tgr7_0470	COG0789	Transcriptional regulator
Tgr7_0478	COG3660	Nucleoside-diphosphate-sugar epimerase
Tgr7_0480	COG1560	Kdo2-lipid A biosynthetic process
Tgr7_0481	COG1519	Transferase
Tgr7_0483	COG1538	Outer membrane efflux protein
Tgr7_0487	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
Tgr7_0489	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Tgr7_0489	COG0069	glutamate synthase activity
Tgr7_0492	COG1278	Cold shock
Tgr7_0495	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
Tgr7_0497	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Tgr7_0498	COG5001	Diguanylate cyclase
Tgr7_0498	COG5002	protein histidine kinase activity
Tgr7_0498	COG3447	MASE1 domain protein
Tgr7_0507	COG1278	Cold shock
Tgr7_0509	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
Tgr7_0512	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
Tgr7_0513	COG1792	Involved in formation and maintenance of cell shape
Tgr7_0514	COG1077	Cell shape determining protein MreB Mrl
Tgr7_0515	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Tgr7_0516	COG0154	amidase activity
Tgr7_0517	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Tgr7_0518	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
Tgr7_0519	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
Tgr7_0522	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Tgr7_0523	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Tgr7_0525	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
Tgr7_0526	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Tgr7_0527	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Tgr7_0528	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Tgr7_0529	COG0193	aminoacyl-tRNA hydrolase activity
Tgr7_0530	COG0012	GTP binding
Tgr7_0547	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Tgr7_0552	COG1477	protein flavinylation
Tgr7_0555	COG1446	asparaginase
Tgr7_0566	COG3178	'Phosphotransferase
Tgr7_0571	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Tgr7_0572	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
Tgr7_0572	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Tgr7_0575	COG0569	domain protein
Tgr7_0575	COG0189	ligase activity
Tgr7_0578	COG0129	dihydroxy-acid dehydratase activity
Tgr7_0580	COG0840	transmembrane signaling receptor activity
Tgr7_0583	COG3263	regulation of cellular component size
Tgr7_0588	COG0745	RESPONSE REGULATOR receiver
Tgr7_0589	COG2205	protein histidine kinase activity
Tgr7_0596	COG2205	protein histidine kinase activity
Tgr7_0601	COG3586	endonuclease activity
Tgr7_0604	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
Tgr7_0608	COG0659	secondary active sulfate transmembrane transporter activity
Tgr7_0616	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
Tgr7_0617	COG0583	DNA-binding transcription factor activity
Tgr7_0618	COG3039	Transposase
Tgr7_0623	COG3177	Filamentation induced by cAMP protein fic
Tgr7_0624	COG0531	amino acid
Tgr7_0626	COG0210	DNA helicase
Tgr7_0628	COG2026	Addiction module toxin, RelE StbE family
Tgr7_0630	COG3023	N-Acetylmuramoyl-L-alanine amidase
Tgr7_0631	COG3278	Belongs to the heme-copper respiratory oxidase family
Tgr7_0634	COG2010	Cytochrome c
Tgr7_0638	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Tgr7_0642	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Tgr7_0643	COG0432	Pfam Uncharacterised protein family UPF0047
Tgr7_0645	COG3300	MHYT domain
Tgr7_0645	COG5001	Diguanylate cyclase
Tgr7_0647	COG0483	inositol monophosphate 1-phosphatase activity
Tgr7_0648	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
Tgr7_0650	COG0646	methionine synthase
Tgr7_0650	COG1410	methionine synthase
Tgr7_0654	COG2831	hemolysin activation secretion protein
Tgr7_0656	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Tgr7_0656	COG3153	acetyltransferase
Tgr7_0661	COG0412	Dienelactone hydrolase
Tgr7_0665	COG1643	Atp-dependent helicase
Tgr7_0673	COG0483	inositol monophosphate 1-phosphatase activity
Tgr7_0678	COG0583	DNA-binding transcription factor activity
Tgr7_0685	COG2863	cytochrome
Tgr7_0686	COG0446	pyridine nucleotide-disulphide oxidoreductase
Tgr7_0689	COG3706	GGDEF domain
Tgr7_0690	COG0488	(ABC) transporter
Tgr7_0692	COG3415	Transposase
Tgr7_0692	COG2801	Transposase and inactivated derivatives
Tgr7_0693	COG2095	MarC family integral membrane protein
Tgr7_0694	COG1580	Controls the rotational direction of flagella during chemotaxis
Tgr7_0696	COG2918	glutathione biosynthetic process
Tgr7_0697	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Tgr7_0697	COG4797	methyltransferase
Tgr7_0699	COG2815	serine threonine protein kinase
Tgr7_0699	COG0515	serine threonine protein kinase
Tgr7_0701	COG2259	Doxx family
Tgr7_0702	COG0435	Glutathione S-transferase
Tgr7_0704	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Tgr7_0705	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Tgr7_0706	COG2203	Gaf domain
Tgr7_0706	COG4251	negative regulation of phosphorylation
Tgr7_0706	COG3706	GGDEF domain
Tgr7_0706	COG5001	Diguanylate cyclase
Tgr7_0708	COG0438	transferase activity, transferring glycosyl groups
Tgr7_0710	COG0271	Belongs to the BolA IbaG family
Tgr7_0714	COG0308	aminopeptidase N
Tgr7_0718	COG1262	PFAM Formylglycine-generating sulfatase enzyme
Tgr7_0719	COG3706	GGDEF domain
Tgr7_0720	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
Tgr7_0721	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
Tgr7_0721	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
Tgr7_0722	COG1660	Displays ATPase and GTPase activities
Tgr7_0723	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
Tgr7_0726	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
Tgr7_0727	COG1137	ATPase activity
Tgr7_0730	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
Tgr7_0737	COG1127	ABC transporter
Tgr7_0738	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Tgr7_0739	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Tgr7_0742	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
Tgr7_0743	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Tgr7_0744	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
Tgr7_0746	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Tgr7_0747	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Tgr7_0748	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Tgr7_0749	COG0723	plastoquinol--plastocyanin reductase activity
Tgr7_0750	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Tgr7_0751	COG2857	Cytochrome c1
Tgr7_0752	COG0625	glutathione transferase activity
Tgr7_0753	COG2969	positive regulation of protein catabolic process
Tgr7_0755	COG0277	FAD linked oxidase domain protein
Tgr7_0756	COG0792	nuclease activity
Tgr7_0757	COG3107	peptidoglycan biosynthetic process
Tgr7_0760	COG2001	Belongs to the MraZ family
Tgr7_0761	COG0275	rRNA processing
Tgr7_0762	COG3116	cell division
Tgr7_0764	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Tgr7_0765	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Tgr7_0766	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Tgr7_0767	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Tgr7_0768	COG0772	Belongs to the SEDS family
Tgr7_0769	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Tgr7_0770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Tgr7_0771	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Tgr7_0772	COG1181	Belongs to the D-alanine--D-alanine ligase family
Tgr7_0773	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
Tgr7_0775	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Tgr7_0776	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
Tgr7_0778	COG0739	heme binding
Tgr7_0779	COG0653	protein targeting
Tgr7_0780	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Tgr7_0781	COG0494	nUDIX hydrolase
Tgr7_0783	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
Tgr7_0784	COG0237	dephospho-CoA kinase activity
Tgr7_0788	COG1132	(ABC) transporter
Tgr7_0799	COG1115	amino acid carrier protein
Tgr7_0804	COG0517	IMP dehydrogenase activity
Tgr7_0808	COG0045	succinate-CoA ligase (ADP-forming) activity
Tgr7_0810	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
Tgr7_0811	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Tgr7_0811	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Tgr7_0812	COG0347	Belongs to the P(II) protein family
Tgr7_0813	COG0778	Nitroreductase
Tgr7_0817	COG0542	response to heat
Tgr7_0824	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Tgr7_0825	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Tgr7_0826	COG2716	regulation of RNA biosynthetic process
Tgr7_0827	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Tgr7_0828	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
Tgr7_0829	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
Tgr7_0830	COG1469	GTP cyclohydrolase I activity
Tgr7_0832	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Tgr7_0833	COG0142	geranyltranstransferase activity
Tgr7_0834	COG1722	exodeoxyribonuclease VII activity
Tgr7_0835	COG1592	Rubrerythrin
Tgr7_0842	COG4536	flavin adenine dinucleotide binding
Tgr7_0843	COG4137	Cytochrome C assembly protein
Tgr7_0844	COG1234	tRNA 3'-trailer cleavage
Tgr7_0845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Tgr7_0846	COG0228	four-way junction DNA binding
Tgr7_0847	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Tgr7_0848	COG0336	Belongs to the RNA methyltransferase TrmD family
Tgr7_0849	COG0335	large ribosomal subunit rRNA binding
Tgr7_0851	COG0840	transmembrane signaling receptor activity
Tgr7_0852	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Tgr7_0853	COG3258	Cytochrome c
Tgr7_0854	COG2010	Cytochrome c
Tgr7_0855	COG3258	Cytochrome c
Tgr7_0856	COG2010	Cytochrome c
Tgr7_0857	COG3258	Cytochrome c
Tgr7_0859	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
Tgr7_0860	COG0326	Molecular chaperone. Has ATPase activity
Tgr7_0865	COG4772	TonB-dependent receptor
Tgr7_0866	COG0589	response to stress
Tgr7_0867	COG0490	domain, Protein
Tgr7_0867	COG0471	metal ion transport
Tgr7_0871	COG0166	Belongs to the GPI family
Tgr7_0872	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Tgr7_0873	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Tgr7_0874	COG0297	glycogen (starch) synthase activity
Tgr7_0875	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Tgr7_0877	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Tgr7_0878	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Tgr7_0879	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Tgr7_0880	COG1428	Deoxynucleoside kinase
Tgr7_0883	COG2816	NAD+ diphosphatase activity
Tgr7_0886	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
Tgr7_0887	COG2983	Belongs to the UPF0260 family
Tgr7_0892	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
Tgr7_0892	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
Tgr7_0893	COG0802	atpase or kinase
Tgr7_0894	COG0860	N-Acetylmuramoyl-L-alanine amidase
Tgr7_0895	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
Tgr7_0896	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Tgr7_0897	COG1923	regulation of RNA biosynthetic process
Tgr7_0898	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Tgr7_0899	COG0330	HflC and HflK could
Tgr7_0900	COG0330	HflC and HflK could
Tgr7_0902	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
Tgr7_0903	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Tgr7_0904	COG1028	Short-chain dehydrogenase reductase Sdr
Tgr7_0909	COG3039	Transposase
Tgr7_0920	COG0537	adenosine 5'-monophosphoramidase activity
Tgr7_0923	COG0360	Binds together with S18 to 16S ribosomal RNA
Tgr7_0924	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Tgr7_0926	COG0359	binds to the 23S rRNA
Tgr7_0927	COG0305	Participates in initiation and elongation during chromosome replication
Tgr7_0928	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Tgr7_0931	COG2379	hydroxypyruvate reductase
Tgr7_0932	COG2833	Protein of unknown function (DUF455)
Tgr7_0933	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Tgr7_0934	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Tgr7_0935	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Tgr7_0936	COG0215	cysteine-tRNA ligase activity
Tgr7_0937	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Tgr7_0938	COG0544	peptidyl-prolyl cis-trans isomerase activity
Tgr7_0939	COG0740	serine-type endopeptidase activity
Tgr7_0940	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Tgr7_0941	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
Tgr7_0945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Tgr7_0948	COG0601	transmembrane transport
Tgr7_0949	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Tgr7_0952	COG0631	protein serine/threonine phosphatase activity
Tgr7_0953	COG1388	LysM domain
Tgr7_0953	COG0741	lytic transglycosylase activity
Tgr7_0956	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
Tgr7_0962	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Tgr7_0963	COG0733	neurotransmitter:sodium symporter activity
Tgr7_0964	COG2867	negative regulation of translational initiation
Tgr7_0965	COG2914	Belongs to the UPF0125 (RnfH) family
Tgr7_0966	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Tgr7_0967	COG0735	belongs to the Fur family
Tgr7_0968	COG0497	DNA recombination
Tgr7_0969	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Tgr7_0970	COG1420	regulation of RNA biosynthetic process
Tgr7_0971	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Tgr7_0972	COG0443	Heat shock 70 kDa protein
Tgr7_0973	COG0484	heat shock protein binding
Tgr7_0974	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Tgr7_0975	COG0505	Belongs to the CarA family
Tgr7_0978	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Tgr7_0980	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
Tgr7_0981	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Tgr7_0982	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Tgr7_0983	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Tgr7_0984	COG0149	triose-phosphate isomerase activity
Tgr7_0986	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Tgr7_0987	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Tgr7_0988	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Tgr7_0989	COG0649	NAD binding
Tgr7_0992	COG1034	ATP synthesis coupled electron transport
Tgr7_0993	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Tgr7_0994	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Tgr7_0996	COG0713	ATP synthesis coupled electron transport
Tgr7_0999	COG1007	ATP synthesis coupled electron transport
Tgr7_1001	COG0779	Required for maturation of 30S ribosomal subunits
Tgr7_1002	COG0195	Participates in both transcription termination and antitermination
Tgr7_1002	COG2251	uridine kinase activity
Tgr7_1003	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Tgr7_1004	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Tgr7_1005	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Tgr7_1006	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Tgr7_1007	COG1185	polyribonucleotide nucleotidyltransferase activity
Tgr7_1008	COG0429	hydrolase of the alpha beta-hydrolase fold
Tgr7_1012	COG2308	Evidence 4 Homologs of previously reported genes of
Tgr7_1015	COG2308	Evidence 4 Homologs of previously reported genes of
Tgr7_1015	COG2307	Protein conserved in bacteria
Tgr7_1019	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Tgr7_1022	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Tgr7_1024	COG2176	DNA-directed DNA polymerase activity
Tgr7_1029	COG3852	Histidine kinase
Tgr7_1031	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Tgr7_1032	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Tgr7_1033	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Tgr7_1034	COG1570	exodeoxyribonuclease VII activity
Tgr7_1036	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Tgr7_1036	COG0519	Catalyzes the synthesis of GMP from XMP
Tgr7_1037	COG0590	tRNA wobble adenosine to inosine editing
Tgr7_1042	COG3039	Transposase
Tgr7_1043	COG0326	Molecular chaperone. Has ATPase activity
Tgr7_1046	COG5001	Diguanylate cyclase
Tgr7_1046	COG3300	MHYT domain
Tgr7_1049	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
Tgr7_1050	COG2267	carboxylic ester hydrolase activity
Tgr7_1053	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Tgr7_1053	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Tgr7_1054	COG0564	pseudouridine synthase activity
Tgr7_1055	COG0330	HflC and HflK could
Tgr7_1057	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Tgr7_1059	COG4681	YaeQ
Tgr7_1060	COG0700	Nucleoside recognition
Tgr7_1061	COG1403	HNH endonuclease
Tgr7_1063	COG0784	Response regulator, receiver
Tgr7_1063	COG0835	chemotaxis
Tgr7_1070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Tgr7_1073	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
Tgr7_1074	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
Tgr7_1075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Tgr7_1076	COG0537	adenosine 5'-monophosphoramidase activity
Tgr7_1080	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
Tgr7_1085	COG3026	antisigma factor binding
Tgr7_1087	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Tgr7_1089	COG0481	GTPase activity
Tgr7_1090	COG0681	Belongs to the peptidase S26 family
Tgr7_1092	COG0571	ribonuclease III activity
Tgr7_1093	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Tgr7_1094	COG1381	Involved in DNA repair and RecF pathway recombination
Tgr7_1095	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
Tgr7_1096	COG0736	holo-[acyl-carrier-protein] synthase activity
Tgr7_1097	COG0784	Response regulator, receiver
Tgr7_1097	COG2205	protein histidine kinase activity
Tgr7_1097	COG5002	protein histidine kinase activity
Tgr7_1102	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Tgr7_1105	COG3093	addiction module antidote protein HigA
Tgr7_1107	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
Tgr7_1109	COG0501	Belongs to the peptidase M48B family
Tgr7_1114	COG5002	protein histidine kinase activity
Tgr7_1114	COG5001	Diguanylate cyclase
Tgr7_1115	COG0784	Response regulator, receiver
Tgr7_1116	COG4251	negative regulation of phosphorylation
Tgr7_1119	COG4269	membrane
Tgr7_1120	COG0501	Belongs to the peptidase M48B family
Tgr7_1125	COG0442	prolyl-tRNA aminoacylation
Tgr7_1128	COG1566	PFAM secretion protein HlyD family protein
Tgr7_1136	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Tgr7_1140	COG0300	oxidoreductase activity
Tgr7_1144	COG5001	Diguanylate cyclase
Tgr7_1144	COG5002	protein histidine kinase activity
Tgr7_1145	COG4251	negative regulation of phosphorylation
Tgr7_1147	COG3064	Membrane
Tgr7_1150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Tgr7_1151	COG1393	Belongs to the ArsC family
Tgr7_1152	COG2171	N-acyltransferase activity
Tgr7_1153	COG0436	Aminotransferase
Tgr7_1156	COG3039	Transposase
Tgr7_1157	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Tgr7_1158	COG0024	Methionine aminopeptidase
Tgr7_1159	COG0052	Belongs to the universal ribosomal protein uS2 family
Tgr7_1160	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Tgr7_1161	COG0528	UMP kinase activity
Tgr7_1162	COG0233	cytoplasmic translational termination
Tgr7_1163	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Tgr7_1164	COG0575	Belongs to the CDS family
Tgr7_1165	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
Tgr7_1166	COG0750	zinc metalloprotease
Tgr7_1167	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Tgr7_1170	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Tgr7_1171	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Tgr7_1172	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
Tgr7_1174	COG0673	inositol 2-dehydrogenase activity
Tgr7_1175	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Tgr7_1177	COG0825	malonyl-CoA metabolic process
Tgr7_1178	COG0037	tRNA processing
Tgr7_1182	COG0504	CTP synthase activity
Tgr7_1183	COG2877	3-deoxy-8-phosphooctulonate synthase activity
Tgr7_1184	COG0148	phosphopyruvate hydratase activity
Tgr7_1185	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
Tgr7_1186	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Tgr7_1187	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Tgr7_1189	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Tgr7_1192	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
Tgr7_1194	COG1965	Belongs to the frataxin family
Tgr7_1195	COG2363	Small membrane protein
Tgr7_1196	COG1666	GTP binding
Tgr7_1199	COG0742	ribosomal rna small subunit methyltransferase
Tgr7_1200	COG2900	Belongs to the SlyX family
Tgr7_1201	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Tgr7_1204	COG2132	Multicopper oxidase
Tgr7_1211	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
Tgr7_1215	COG0784	Response regulator, receiver
Tgr7_1215	COG0835	chemotaxis
Tgr7_1217	COG1815	bacterial-type flagellum-dependent cell motility
Tgr7_1218	COG1558	bacterial-type flagellum-dependent cell motility
Tgr7_1219	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
Tgr7_1220	COG1749	Flagellar hook protein flgE
Tgr7_1221	COG4787	bacterial-type flagellum-dependent cell motility
Tgr7_1222	COG4786	Flagellar basal body rod
Tgr7_1223	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
Tgr7_1225	COG1705	Flagellar rod assembly protein muramidase FlgJ
Tgr7_1225	COG3951	Flagellar rod assembly protein muramidase FlgJ
Tgr7_1228	COG0235	Class ii aldolase
Tgr7_1231	COG1509	lysine 2,3-aminomutase activity
Tgr7_1232	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Tgr7_1233	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
Tgr7_1234	COG0688	phosphatidylethanolamine metabolic process
Tgr7_1239	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Tgr7_1241	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Tgr7_1245	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Tgr7_1246	COG0066	3-isopropylmalate dehydratase activity
Tgr7_1248	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
Tgr7_1251	COG0101	tRNA pseudouridine synthase activity
Tgr7_1252	COG0135	phosphoribosylanthranilate isomerase activity
Tgr7_1253	COG0133	tryptophan synthase activity
Tgr7_1254	COG0159	tryptophan synthase activity
Tgr7_1255	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
Tgr7_1256	COG0285	dihydrofolate synthase activity
Tgr7_1258	COG1286	toxin biosynthetic process
Tgr7_1260	COG1376	ErfK ybiS ycfS ynhG family protein
Tgr7_1261	COG1177	transmembrane transport
Tgr7_1262	COG1176	ABC-type spermidine putrescine transport system, permease component I
Tgr7_1263	COG3842	ATPase activity
Tgr7_1267	COG0247	lactate metabolic process
Tgr7_1267	COG2181	nitrate reductase activity
Tgr7_1273	COG0375	protein maturation
Tgr7_1276	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
Tgr7_1281	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
Tgr7_1282	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
Tgr7_1285	COG1546	Belongs to the CinA family
Tgr7_1286	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
Tgr7_1287	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Tgr7_1288	COG2137	regulation of response to DNA damage stimulus
Tgr7_1289	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Tgr7_1290	COG0527	aspartate kinase activity
Tgr7_1291	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
Tgr7_1295	COG2010	Cytochrome c
Tgr7_1295	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Tgr7_1299	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Tgr7_1301	COG0372	Belongs to the citrate synthase family
Tgr7_1308	COG3039	Transposase
Tgr7_1317	COG1943	Transposase
Tgr7_1326	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Tgr7_1332	COG1987	bacterial-type flagellum assembly
Tgr7_1334	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Tgr7_1335	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
Tgr7_1337	COG0455	bacterial-type flagellum organization
Tgr7_1340	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
Tgr7_1341	COG2198	Histidine kinase
Tgr7_1341	COG0643	Histidine kinase
Tgr7_1342	COG2201	protein-glutamate methylesterase activity
Tgr7_1343	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
Tgr7_1344	COG1360	Flagellar Motor Protein
Tgr7_1345	COG1192	Involved in chromosome partitioning
Tgr7_1347	COG0835	chemotaxis
Tgr7_1352	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Tgr7_1353	COG1530	ribonuclease E activity
Tgr7_1356	COG0616	signal peptide processing
Tgr7_1356	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Tgr7_1358	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
Tgr7_1361	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Tgr7_1362	COG2957	Belongs to the agmatine deiminase family
Tgr7_1364	COG1489	DNA binding
Tgr7_1365	COG4591	ABC-type transport system involved in lipoprotein release permease component
Tgr7_1366	COG1136	(ABC) transporter
Tgr7_1368	COG2333	competence protein COMEC
Tgr7_1368	COG0658	competence protein
Tgr7_1369	COG0811	peptide transport
Tgr7_1371	COG1132	(ABC) transporter
Tgr7_1373	COG1663	tetraacyldisaccharide 4'-kinase activity
Tgr7_1374	COG2835	tetraacyldisaccharide 4'-kinase activity
Tgr7_1375	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
Tgr7_1377	COG0494	nUDIX hydrolase
Tgr7_1379	COG3437	response regulator, receiver
Tgr7_1380	COG3706	GGDEF domain
Tgr7_1383	COG2153	protein acetylation
Tgr7_1387	COG2211	Major facilitator Superfamily
Tgr7_1388	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Tgr7_1391	COG0386	Belongs to the glutathione peroxidase family
Tgr7_1392	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Tgr7_1393	COG0302	gtp cyclohydrolase
Tgr7_1394	COG0415	Belongs to the DNA photolyase family
Tgr7_1395	COG1028	Short-chain dehydrogenase reductase Sdr
Tgr7_1396	COG3046	protein related to deoxyribodipyrimidine photolyase
Tgr7_1398	COG4221	oxidoreductase activity
Tgr7_1400	COG1331	Highly conserved protein containing a thioredoxin domain
Tgr7_1402	COG1388	LysM domain
Tgr7_1402	COG0791	NLP P60 protein
Tgr7_1405	COG0745	RESPONSE REGULATOR receiver
Tgr7_1405	COG3706	GGDEF domain
Tgr7_1407	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Tgr7_1409	COG1199	ATP-dependent helicase activity
Tgr7_1411	COG0585	pseudouridine synthase activity
Tgr7_1412	COG1278	Cold shock
Tgr7_1420	COG2203	Gaf domain
Tgr7_1420	COG3706	GGDEF domain
Tgr7_1420	COG4251	negative regulation of phosphorylation
Tgr7_1420	COG5001	Diguanylate cyclase
Tgr7_1425	COG0840	transmembrane signaling receptor activity
Tgr7_1429	COG1366	Belongs to the anti-sigma-factor antagonist family
Tgr7_1431	COG2840	Smr protein MutS2
Tgr7_1432	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
Tgr7_1433	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
Tgr7_1438	COG0436	Aminotransferase
Tgr7_1440	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Tgr7_1444	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Tgr7_1445	COG3706	GGDEF domain
Tgr7_1445	COG0745	RESPONSE REGULATOR receiver
Tgr7_1448	COG0488	(ABC) transporter
Tgr7_1450	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Tgr7_1452	COG0291	Belongs to the bacterial ribosomal protein bL35 family
Tgr7_1453	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Tgr7_1454	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Tgr7_1455	COG0072	phenylalanine-tRNA ligase activity
Tgr7_1456	COG0776	regulation of translation
Tgr7_1460	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
Tgr7_1462	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Tgr7_1465	COG2009	succinate dehydrogenase
Tgr7_1466	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
Tgr7_1467	COG1053	succinate dehydrogenase
Tgr7_1471	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
Tgr7_1472	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
Tgr7_1473	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
Tgr7_1479	COG1136	(ABC) transporter
Tgr7_1482	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
Tgr7_1484	COG0033	Phosphoglucomutase
Tgr7_1486	COG1959	2 iron, 2 sulfur cluster binding
Tgr7_1487	COG1104	cysteine desulfurase activity
Tgr7_1491	COG0714	Associated with various cellular activities
Tgr7_1492	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Tgr7_1494	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Tgr7_1495	COG1127	ABC transporter
Tgr7_1504	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
Tgr7_1505	COG0604	alcohol dehydrogenase
Tgr7_1507	COG2079	MmgE PrpD family protein
Tgr7_1512	COG3243	poly(R)-hydroxyalkanoic acid synthase
Tgr7_1515	COG1028	Short-chain dehydrogenase reductase Sdr
Tgr7_1516	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
Tgr7_1519	COG1028	Short-chain dehydrogenase reductase Sdr
Tgr7_1522	COG1028	Short-chain dehydrogenase reductase Sdr
Tgr7_1523	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Tgr7_1524	COG1562	ergosterol biosynthetic process
Tgr7_1528	COG1322	Protein conserved in bacteria
Tgr7_1531	COG0402	S-adenosylhomocysteine deaminase activity
Tgr7_1533	COG0668	transmembrane transport
Tgr7_1534	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
Tgr7_1536	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Tgr7_1537	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Tgr7_1538	COG0077	Prephenate dehydratase
Tgr7_1538	COG1605	Chorismate mutase
Tgr7_1540	COG0287	Prephenate dehydrogenase
Tgr7_1541	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Tgr7_1542	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Tgr7_1543	COG0539	negative regulation of cytoplasmic translation
Tgr7_1544	COG0776	regulation of translation
Tgr7_1546	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
Tgr7_1547	COG0284	orotidine-5'-phosphate decarboxylase activity
Tgr7_1548	COG1555	photosystem II stabilization
Tgr7_1548	COG1596	polysaccharide export
Tgr7_1551	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Tgr7_1552	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Tgr7_1557	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Tgr7_1558	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Tgr7_1559	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Tgr7_1559	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Tgr7_1562	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Tgr7_1565	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
Tgr7_1569	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Tgr7_1574	COG2249	NAD(P)H dehydrogenase (quinone) activity
Tgr7_1575	COG2027	D-alanyl-D-alanine carboxypeptidase
Tgr7_1576	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Tgr7_1577	COG4139	cobalamin transport
Tgr7_1578	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Tgr7_1579	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Tgr7_1588	COG4243	Vitamin k epoxide reductase
Tgr7_1591	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
Tgr7_1594	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
Tgr7_1596	COG2208	phosphoserine phosphatase activity
Tgr7_1599	COG2203	Gaf domain
Tgr7_1599	COG3706	GGDEF domain
Tgr7_1599	COG4251	negative regulation of phosphorylation
Tgr7_1599	COG5001	Diguanylate cyclase
Tgr7_1603	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Tgr7_1605	COG0616	signal peptide processing
Tgr7_1607	COG1704	LemA family
Tgr7_1608	COG0501	Belongs to the peptidase M48B family
Tgr7_1610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Tgr7_1611	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
Tgr7_1613	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
Tgr7_1637	COG4397	Mu-like prophage major head subunit gpT
Tgr7_1641	COG4383	Mu-like prophage protein gp29
Tgr7_1642	COG4373	Mu-like prophage FluMu protein gp28
Tgr7_1664	COG2842	Transposition protein
Tgr7_1665	COG2801	Transposase and inactivated derivatives
Tgr7_1673	COG0596	Alpha beta hydrolase
Tgr7_1675	COG5002	protein histidine kinase activity
Tgr7_1675	COG5001	Diguanylate cyclase
Tgr7_1675	COG3447	MASE1 domain protein
Tgr7_1678	COG0513	Belongs to the DEAD box helicase family
Tgr7_1679	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Tgr7_1682	COG0583	DNA-binding transcription factor activity
Tgr7_1683	COG0655	NAD(P)H dehydrogenase (quinone) activity
Tgr7_1685	COG5265	(ABC) transporter
Tgr7_1686	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Tgr7_1692	COG0430	RNA-3'-phosphate cyclase activity
Tgr7_1693	COG0788	formyltetrahydrofolate deformylase activity
Tgr7_1696	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Tgr7_1696	COG0446	pyridine nucleotide-disulphide oxidoreductase
Tgr7_1699	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Tgr7_1701	COG0069	glutamate synthase activity
Tgr7_1708	COG2944	sequence-specific DNA binding
Tgr7_1710	COG2226	methyltransferase
Tgr7_1712	COG1595	DNA-templated transcription, initiation
Tgr7_1714	COG3039	Transposase
Tgr7_1715	COG2226	methyltransferase
Tgr7_1718	COG2129	metallophosphoesterase
Tgr7_1721	COG1509	lysine 2,3-aminomutase activity
Tgr7_1725	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Tgr7_1726	COG0745	RESPONSE REGULATOR receiver
Tgr7_1726	COG3706	GGDEF domain
Tgr7_1727	COG1228	amidohydrolase
Tgr7_1729	COG0281	malic enzyme
Tgr7_1729	COG0280	phosphate acetyltransferase
Tgr7_1731	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
Tgr7_1737	COG0446	pyridine nucleotide-disulphide oxidoreductase
Tgr7_1739	COG2204	response regulator
Tgr7_1749	COG2188	Transcriptional regulator
Tgr7_1754	COG1472	Belongs to the glycosyl hydrolase 3 family
Tgr7_1758	COG1376	ErfK ybiS ycfS ynhG family protein
Tgr7_1759	COG0556	nucleotide-excision repair
Tgr7_1764	COG0420	3'-5' exonuclease activity
Tgr7_1772	COG1074	ATP-dependent DNA helicase activity
Tgr7_1775	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
Tgr7_1800	COG1518	maintenance of DNA repeat elements
Tgr7_1800	COG1468	defense response to virus
Tgr7_1815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Tgr7_1822	COG2199	diguanylate cyclase activity
Tgr7_1822	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
Tgr7_1826	COG0084	hydrolase, TatD family'
Tgr7_1829	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
Tgr7_1830	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Tgr7_1832	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
Tgr7_1833	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
Tgr7_1834	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Tgr7_1835	COG1028	Short-chain dehydrogenase reductase Sdr
Tgr7_1838	COG0542	response to heat
Tgr7_1839	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Tgr7_1842	COG0482	sulfurtransferase activity
Tgr7_1843	COG2915	High frequency lysogenization protein hflD homolog
Tgr7_1849	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Tgr7_1850	COG2850	peptidyl-arginine hydroxylation
Tgr7_1852	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
Tgr7_1853	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Tgr7_1855	COG2205	protein histidine kinase activity
Tgr7_1858	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Tgr7_1859	COG1131	(ABC) transporter
Tgr7_1860	COG0842	Transport permease protein
Tgr7_1866	COG4804	nuclease activity
Tgr7_1867	COG2003	Belongs to the UPF0758 family
Tgr7_1870	COG1475	DNA binding
Tgr7_1873	COG5489	Protein of unknown function (DUF736)
Tgr7_1879	COG1192	Involved in chromosome partitioning
Tgr7_1882	COG4959	Type IV secretory pathway protease TraF
Tgr7_1884	COG0745	RESPONSE REGULATOR receiver
Tgr7_1885	COG2205	protein histidine kinase activity
Tgr7_1888	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Tgr7_1889	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Tgr7_1891	COG0583	DNA-binding transcription factor activity
Tgr7_1895	COG4962	Type ii secretion system protein e
Tgr7_1896	COG3838	Conjugal transfer protein Trbc
Tgr7_1898	COG3451	type IV secretory pathway VirB4
Tgr7_1907	COG0322	excinuclease ABC activity
Tgr7_1908	COG1573	uracil-dna glycosylase
Tgr7_1909	COG2197	response regulator
Tgr7_1911	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
Tgr7_1912	COG0416	fatty acid biosynthetic process
Tgr7_1913	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Tgr7_1914	COG1399	metal-binding, possibly nucleic acid-binding protein
Tgr7_1915	COG0439	Biotin carboxylase
Tgr7_1917	COG0424	maF-like protein
Tgr7_1919	COG0039	L-malate dehydrogenase activity
Tgr7_1925	COG0640	Transcriptional regulator
Tgr7_1931	COG0514	ATP-dependent DNA helicase (RecQ)
Tgr7_1933	COG2084	Dehydrogenase
Tgr7_1934	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
Tgr7_1935	COG2894	cell division
Tgr7_1936	COG0850	regulation of cytokinetic process
Tgr7_1939	COG2161	toxin-antitoxin pair type II binding
Tgr7_1940	COG4115	mRNA cleavage
Tgr7_1955	COG3023	N-Acetylmuramoyl-L-alanine amidase
Tgr7_1958	COG1215	transferase activity, transferring glycosyl groups
Tgr7_1959	COG0398	Pfam SNARE associated Golgi protein
Tgr7_1961	COG0640	Transcriptional regulator
Tgr7_1962	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Tgr7_1972	COG2204	response regulator
Tgr7_1973	COG2204	response regulator
Tgr7_1988	COG2944	sequence-specific DNA binding
Tgr7_1990	COG5002	protein histidine kinase activity
Tgr7_1990	COG5001	Diguanylate cyclase
Tgr7_1992	COG0598	Magnesium transport protein CorA
Tgr7_1999	COG0438	transferase activity, transferring glycosyl groups
Tgr7_2000	COG2239	Acts as a magnesium transporter
Tgr7_2001	COG2239	Acts as a magnesium transporter
Tgr7_2002	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
Tgr7_2003	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
Tgr7_2004	COG1674	ftsk spoiiie
Tgr7_2005	COG0686	Belongs to the AlaDH PNT family
Tgr7_2006	COG0492	ferredoxin-NADP+ reductase activity
Tgr7_2008	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Tgr7_2011	COG0521	Mo-molybdopterin cofactor biosynthetic process
Tgr7_2012	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Tgr7_2013	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
Tgr7_2014	COG0180	Tryptophanyl-tRNA synthetase
Tgr7_2016	COG1994	Peptidase M50
Tgr7_2017	COG0009	L-threonylcarbamoyladenylate synthase
Tgr7_2018	COG2917	probably involved in intracellular septation
Tgr7_2019	COG2350	Protein conserved in bacteria
Tgr7_2020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Tgr7_2022	COG1360	Flagellar Motor Protein
Tgr7_2024	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Tgr7_2027	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Tgr7_2028	COG1070	Carbohydrate kinase
Tgr7_2029	COG1073	alpha beta
Tgr7_2031	COG1414	Transcriptional regulator
Tgr7_2032	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Tgr7_2037	COG0277	FAD linked oxidase domain protein
Tgr7_2038	COG0277	FAD linked oxidase domain protein
Tgr7_2039	COG0247	lactate metabolic process
Tgr7_2041	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
Tgr7_2042	COG1970	mechanosensitive ion channel activity
Tgr7_2043	COG0436	Aminotransferase
Tgr7_2044	COG0739	heme binding
Tgr7_2045	COG1160	GTP binding
Tgr7_2047	COG2976	Protein conserved in bacteria
Tgr7_2048	COG0124	histidyl-tRNA synthetase
Tgr7_2051	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Tgr7_2052	COG0105	UTP biosynthetic process
Tgr7_2057	COG0316	Belongs to the HesB IscA family
Tgr7_2059	COG1104	cysteine desulfurase activity
Tgr7_2060	COG1959	2 iron, 2 sulfur cluster binding
Tgr7_2065	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Tgr7_2066	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Tgr7_2067	COG1862	Preprotein translocase
Tgr7_2068	COG0343	queuine tRNA-ribosyltransferase activity
Tgr7_2069	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
Tgr7_2073	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
Tgr7_2074	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Tgr7_2076	COG1598	PFAM Uncharacterised protein family UPF0150
Tgr7_2092	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Tgr7_2093	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Tgr7_2094	COG0297	glycogen (starch) synthase activity
Tgr7_2096	COG0438	transferase activity, transferring glycosyl groups
Tgr7_2099	COG0463	Glycosyl transferase, family 2
Tgr7_2101	COG3039	Transposase
Tgr7_2109	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Tgr7_2113	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Tgr7_2114	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
Tgr7_2115	COG4181	ATPase activity
Tgr7_2118	COG0501	Belongs to the peptidase M48B family
Tgr7_2122	COG3657	addiction module killer protein
Tgr7_2124	COG1074	ATP-dependent DNA helicase activity
Tgr7_2125	COG3118	belongs to the thioredoxin family
Tgr7_2126	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
Tgr7_2131	COG1763	Mo-molybdopterin cofactor biosynthetic process
Tgr7_2132	COG0303	'Molybdopterin
Tgr7_2138	COG0795	lipopolysaccharide-transporting ATPase activity
Tgr7_2139	COG0795	lipopolysaccharide-transporting ATPase activity
Tgr7_2140	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Tgr7_2144	COG0525	valine-tRNA ligase activity
Tgr7_2146	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Tgr7_2149	COG1595	DNA-templated transcription, initiation
Tgr7_2151	COG0456	acetyltransferase
Tgr7_2152	COG1573	uracil-dna glycosylase
Tgr7_2153	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Tgr7_2154	COG1183	phosphatidylcholine synthase activity
Tgr7_2155	COG0688	phosphatidylethanolamine metabolic process
Tgr7_2156	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Tgr7_2158	COG0028	Belongs to the TPP enzyme family
Tgr7_2159	COG1193	negative regulation of DNA recombination
Tgr7_2162	COG0123	including yeast histone deacetylase and acetoin utilization protein
Tgr7_2170	COG3850	Histidine kinase
Tgr7_2171	COG2197	response regulator
Tgr7_2173	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Tgr7_2173	COG1648	precorrin-2 dehydrogenase activity
Tgr7_2176	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Tgr7_2185	COG2221	Nitrite and sulphite reductase 4Fe-4S
Tgr7_2186	COG2221	Nitrite and sulphite reductase 4Fe-4S
Tgr7_2187	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
Tgr7_2188	COG2923	Belongs to the DsrF TusC family
Tgr7_2190	COG2920	part of a sulfur-relay system
Tgr7_2193	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
Tgr7_2193	COG0493	'glutamate synthase
Tgr7_2197	COG1797	cobyrinic acid a,c-diamide synthase activity
Tgr7_2198	COG0316	Belongs to the HesB IscA family
Tgr7_2199	COG3128	pkhd-type hydroxylase
Tgr7_2206	COG0095	Lipoate-protein ligase
Tgr7_2208	COG0509	glycine decarboxylation via glycine cleavage system
Tgr7_2210	COG0509	glycine decarboxylation via glycine cleavage system
Tgr7_2211	COG2048	Heterodisulfide reductase, subunit B
Tgr7_2217	COG0425	Belongs to the sulfur carrier protein TusA family
Tgr7_2218	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Tgr7_2220	COG4783	chaperone-mediated protein folding
Tgr7_2225	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Tgr7_2226	COG0602	queuosine metabolic process
Tgr7_2229	COG0823	Involved in the tonB-independent uptake of proteins
Tgr7_2232	COG0811	peptide transport
Tgr7_2233	COG0824	Thioesterase
Tgr7_2234	COG2255	four-way junction helicase activity
Tgr7_2235	COG0632	four-way junction helicase activity
Tgr7_2236	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Tgr7_2237	COG0217	transcriptional regulatory protein
Tgr7_2239	COG0494	nUDIX hydrolase
Tgr7_2240	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Tgr7_2243	COG1254	Belongs to the acylphosphatase family
Tgr7_2246	COG1393	Belongs to the ArsC family
Tgr7_2250	COG0628	permease
Tgr7_2251	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Tgr7_2253	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Tgr7_2254	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
Tgr7_2256	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Tgr7_2260	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Tgr7_2263	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Tgr7_2264	COG0312	modulator of DNA gyrase
Tgr7_2265	COG3028	Belongs to the UPF0307 family
Tgr7_2267	COG0312	modulator of DNA gyrase
Tgr7_2268	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Tgr7_2271	COG1530	ribonuclease E activity
Tgr7_2272	COG0424	maF-like protein
Tgr7_2273	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
Tgr7_2275	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Tgr7_2276	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Tgr7_2277	COG1466	dna polymerase III delta subunit
Tgr7_2279	COG0495	leucyl-tRNA aminoacylation
Tgr7_2281	COG5002	protein histidine kinase activity
Tgr7_2281	COG5001	Diguanylate cyclase
Tgr7_2281	COG3447	MASE1 domain protein
Tgr7_2287	COG0840	transmembrane signaling receptor activity
Tgr7_2288	COG0815	Transfers the fatty acyl group on membrane lipoproteins
Tgr7_2289	COG4535	Mg2 and Co2 transporter CorC
Tgr7_2290	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Tgr7_2291	COG1702	phosphate starvation-inducible protein PhoH
Tgr7_2292	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Tgr7_2294	COG2814	Major facilitator Superfamily
Tgr7_2298	COG0203	ribosomal protein L17
Tgr7_2299	COG0202	RNA polymerase activity
Tgr7_2300	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Tgr7_2301	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Tgr7_2302	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Tgr7_2303	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Tgr7_2304	COG0201	protein transport
Tgr7_2305	COG0200	Binds to the 23S rRNA
Tgr7_2306	COG1841	ribosomal large subunit assembly
Tgr7_2307	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Tgr7_2308	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Tgr7_2309	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Tgr7_2310	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Tgr7_2311	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Tgr7_2312	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Tgr7_2313	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Tgr7_2314	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Tgr7_2315	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Tgr7_2316	COG0255	Belongs to the universal ribosomal protein uL29 family
Tgr7_2317	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Tgr7_2319	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Tgr7_2320	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Tgr7_2321	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Tgr7_2322	COG0089	rRNA binding
Tgr7_2323	COG0088	Forms part of the polypeptide exit tunnel
Tgr7_2324	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Tgr7_2325	COG0051	transcription antitermination factor activity, RNA binding
Tgr7_2326	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Tgr7_2327	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Tgr7_2328	COG0049	tRNA binding
Tgr7_2329	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Tgr7_2330	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Tgr7_2331	COG0085	RNA polymerase activity
Tgr7_2332	COG0222	ribosome binding
Tgr7_2333	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Tgr7_2334	COG0081	regulation of translation
Tgr7_2335	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Tgr7_2338	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Tgr7_2344	COG1091	dTDP-4-dehydrorhamnose reductase activity
Tgr7_2348	COG2852	Protein conserved in bacteria
Tgr7_2349	COG2204	response regulator
Tgr7_2355	COG1216	Glycosyl transferase, family 2
Tgr7_2356	COG1132	(ABC) transporter
Tgr7_2357	COG0438	transferase activity, transferring glycosyl groups
Tgr7_2359	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Tgr7_2360	COG0367	asparagine synthase
Tgr7_2365	COG1216	Glycosyl transferase, family 2
Tgr7_2368	COG0463	Glycosyl transferase, family 2
Tgr7_2372	COG1216	Glycosyl transferase, family 2
Tgr7_2377	COG1045	serine acetyltransferase
Tgr7_2379	COG2755	lipolytic protein G-D-S-L family
Tgr7_2379	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
Tgr7_2380	COG0438	transferase activity, transferring glycosyl groups
Tgr7_2381	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Tgr7_2382	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Tgr7_2383	COG2890	protein-(glutamine-N5) methyltransferase activity
Tgr7_2384	COG0318	PFAM AMP-dependent synthetase and ligase
Tgr7_2387	COG0367	asparagine synthase
Tgr7_2390	COG0489	protein tyrosine kinase activity
Tgr7_2395	COG2204	response regulator
Tgr7_2396	COG3267	Type II secretory pathway component ExeA
Tgr7_2396	COG3409	Peptidoglycan-binding domain 1 protein
Tgr7_2400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
Tgr7_2402	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Tgr7_2404	COG1196	nuclear chromosome segregation
Tgr7_2404	COG0739	heme binding
Tgr7_2404	COG0741	lytic transglycosylase activity
Tgr7_2405	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Tgr7_2406	COG0739	heme binding
Tgr7_2408	COG0316	Belongs to the HesB IscA family
Tgr7_2411	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Tgr7_2415	COG0494	nUDIX hydrolase
Tgr7_2418	COG1773	rubredoxin
Tgr7_2419	COG0351	phosphomethylpyrimidine kinase
Tgr7_2420	COG0352	thiamine-phosphate diphosphorylase activity
Tgr7_2421	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Tgr7_2422	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Tgr7_2423	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Tgr7_2424	COG0730	response to heat
Tgr7_2426	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Tgr7_2431	COG0737	Belongs to the 5'-nucleotidase family
Tgr7_2432	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
Tgr7_2433	COG1518	maintenance of DNA repeat elements
Tgr7_2433	COG1468	defense response to virus
Tgr7_2445	COG0653	protein targeting
Tgr7_2447	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Tgr7_2450	COG2853	Lipoprotein
Tgr7_2451	COG5002	protein histidine kinase activity
Tgr7_2451	COG5001	Diguanylate cyclase
Tgr7_2451	COG3447	MASE1 domain protein
Tgr7_2452	COG0137	argininosuccinate synthase activity
Tgr7_2454	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Tgr7_2455	COG0508	dehydrogenase complex catalyzes the overall conversion of
Tgr7_2456	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Tgr7_2457	COG0418	dihydroorotase activity
Tgr7_2459	COG3706	GGDEF domain
Tgr7_2459	COG0745	RESPONSE REGULATOR receiver
Tgr7_2460	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
Tgr7_2461	COG0367	asparagine synthase
Tgr7_2463	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
Tgr7_2464	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Tgr7_2465	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Tgr7_2466	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Tgr7_2467	COG0248	Ppx GppA phosphatase
Tgr7_2469	COG0306	phosphate transporter
Tgr7_2470	COG1392	Phosphate transport regulator
Tgr7_2473	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
Tgr7_2476	COG2095	MarC family integral membrane protein
Tgr7_2479	COG5001	Diguanylate cyclase
Tgr7_2479	COG3300	MHYT domain
Tgr7_2480	COG3423	Transcriptional regulator
Tgr7_2483	COG3706	GGDEF domain
Tgr7_2494	COG2204	response regulator
Tgr7_2496	COG2205	protein histidine kinase activity
Tgr7_2503	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Tgr7_2503	COG1017	nitric oxide dioxygenase activity
Tgr7_2504	COG3956	TIGRFAM MazG family protein
Tgr7_2508	COG2010	Cytochrome c
Tgr7_2511	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Tgr7_2518	COG2814	Major facilitator Superfamily
Tgr7_2520	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
Tgr7_2521	COG0517	IMP dehydrogenase activity
Tgr7_2522	COG1320	monovalent cation:proton antiporter activity
Tgr7_2523	COG2212	antiporter activity
Tgr7_2528	COG2111	Na H antiporter
Tgr7_2538	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
Tgr7_2543	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Tgr7_2548	COG0842	Transport permease protein
Tgr7_2548	COG1716	ATPase activity
Tgr7_2548	COG1131	(ABC) transporter
Tgr7_2549	COG0583	DNA-binding transcription factor activity
Tgr7_2550	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Tgr7_2551	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Tgr7_2553	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
Tgr7_2557	COG0426	domain, Protein
Tgr7_2557	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Tgr7_2563	COG3901	Regulator of nitric oxide reductase transcription
Tgr7_2563	COG0348	domain, Protein
Tgr7_2564	COG4263	nitrous-oxide reductase activity
Tgr7_2567	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
Tgr7_2569	COG3604	Transcriptional regulator
Tgr7_2582	COG2154	pterin-4-alpha-carbinolamine dehydratase
Tgr7_2584	COG1671	Belongs to the UPF0178 family
Tgr7_2588	COG3706	GGDEF domain
Tgr7_2590	COG2391	methyltransferase activity
Tgr7_2594	COG0668	transmembrane transport
Tgr7_2598	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Tgr7_2600	COG1993	acr, cog1993
Tgr7_2603	COG0579	oxidoreductase
Tgr7_2609	COG1227	inorganic diphosphatase activity
Tgr7_2611	COG0676	glucose-6-phosphate 1-epimerase activity
Tgr7_2614	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Tgr7_2615	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Tgr7_2615	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Tgr7_2619	COG0519	Catalyzes the synthesis of GMP from XMP
Tgr7_2620	COG0717	Belongs to the dCTP deaminase family
Tgr7_2621	COG0489	protein tyrosine kinase activity
Tgr7_2622	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Tgr7_2622	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Tgr7_2623	COG0235	Class ii aldolase
Tgr7_2624	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
Tgr7_2625	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
Tgr7_2626	COG4657	Part of a membrane complex involved in electron transport
Tgr7_2627	COG2878	Part of a membrane complex involved in electron transport
Tgr7_2629	COG4658	electron transport chain
Tgr7_2630	COG4659	FMN binding
Tgr7_2631	COG4660	Part of a membrane complex involved in electron transport
Tgr7_2633	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
Tgr7_2634	COG1595	DNA-templated transcription, initiation
Tgr7_2637	COG2259	Doxx family
Tgr7_2639	COG0659	secondary active sulfate transmembrane transporter activity
Tgr7_2641	COG3220	belongs to the UPF0276 family
Tgr7_2645	COG2210	Belongs to the sulfur carrier protein TusA family
Tgr7_2646	COG1940	carbohydrate kinase activity
Tgr7_2647	COG2096	Adenosyltransferase
Tgr7_2648	COG4206	TonB-dependent receptor
Tgr7_2650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Tgr7_2651	COG0581	inorganic phosphate transmembrane transporter activity
Tgr7_2657	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
Tgr7_2660	COG0730	response to heat
Tgr7_2661	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Tgr7_2661	COG2111	Na H antiporter
Tgr7_2662	COG0651	ATP synthesis coupled electron transport
Tgr7_2663	COG0651	ATP synthesis coupled electron transport
Tgr7_2667	COG1320	monovalent cation:proton antiporter activity
Tgr7_2668	COG2212	antiporter activity
Tgr7_2671	COG2361	Protein of unknown function DUF86
Tgr7_2676	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
Tgr7_2677	COG1628	Protein of unknown function DUF99
Tgr7_2683	COG1355	regulation of microtubule-based process
Tgr7_2688	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Tgr7_2691	COG0189	ligase activity
Tgr7_2696	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Tgr7_2698	COG1280	lysine exporter protein (LysE YggA)
Tgr7_2699	COG4106	trans-aconitate 2-methyltransferase activity
Tgr7_2704	COG0321	lipoyl(octanoyl) transferase activity
Tgr7_2707	COG1686	Belongs to the peptidase S11 family
Tgr7_2709	COG2951	lytic endotransglycosylase activity
Tgr7_2710	COG0772	Belongs to the SEDS family
Tgr7_2711	COG0768	penicillin binding
Tgr7_2712	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Tgr7_2713	COG0563	adenylate kinase activity
Tgr7_2714	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
Tgr7_2715	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
Tgr7_2716	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
Tgr7_2718	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Tgr7_2719	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Tgr7_2720	COG0363	glucosamine-6-phosphate deaminase activity
Tgr7_2721	COG0837	glucose binding
Tgr7_2722	COG2967	ApaG domain
Tgr7_2728	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
Tgr7_2730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Tgr7_2733	COG0671	phosphoesterase, PA-phosphatase related
Tgr7_2738	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Tgr7_2738	COG0426	domain, Protein
Tgr7_2740	COG2860	membrane
Tgr7_2741	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Tgr7_2744	COG1331	Highly conserved protein containing a thioredoxin domain
Tgr7_2745	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
Tgr7_2746	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Tgr7_2747	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Tgr7_2749	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Tgr7_2751	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
Tgr7_2754	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
Tgr7_2755	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Tgr7_2756	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
Tgr7_2757	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Tgr7_2758	COG0509	glycine decarboxylation via glycine cleavage system
Tgr7_2759	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Tgr7_2762	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Tgr7_2763	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
Tgr7_2764	COG0006	proline dipeptidase activity
Tgr7_2769	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Tgr7_2774	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Tgr7_2775	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
Tgr7_2778	COG0247	lactate metabolic process
Tgr7_2788	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Tgr7_2789	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Tgr7_2792	COG0247	lactate metabolic process
Tgr7_2793	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
Tgr7_2794	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
Tgr7_2796	COG1765	OsmC-like protein
Tgr7_2798	COG0134	indole-3-glycerol-phosphate synthase activity
Tgr7_2799	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Tgr7_2800	COG2814	Major facilitator Superfamily
Tgr7_2807	COG0583	DNA-binding transcription factor activity
Tgr7_2809	COG0789	Transcriptional regulator
Tgr7_2811	COG2226	methyltransferase
Tgr7_2813	COG1192	Involved in chromosome partitioning
Tgr7_2823	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Tgr7_2827	COG0798	PFAM Bile acid sodium symporter
Tgr7_2829	COG0346	lactoylglutathione lyase activity
Tgr7_2830	COG0640	Transcriptional regulator
Tgr7_2847	COG3039	Transposase
Tgr7_2850	COG1074	ATP-dependent DNA helicase activity
Tgr7_2861	COG2003	Belongs to the UPF0758 family
Tgr7_2875	COG0582	viral genome integration into host DNA
Tgr7_2878	COG0546	phosphoglycolate phosphatase activity
Tgr7_2879	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Tgr7_2883	COG2813	Specifically methylates the guanine in position
Tgr7_2884	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Tgr7_2885	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
Tgr7_2886	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Tgr7_2887	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
Tgr7_2889	COG0191	fructose-bisphosphate aldolase activity
Tgr7_2890	COG0469	pyruvate kinase activity
Tgr7_2891	COG0126	phosphoglycerate kinase activity
Tgr7_2892	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Tgr7_2894	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Tgr7_2895	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Tgr7_2898	COG1385	rRNA (uridine-N3-)-methyltransferase activity
Tgr7_2901	COG0840	transmembrane signaling receptor activity
Tgr7_2905	COG0189	ligase activity
Tgr7_2910	COG1678	Uncharacterized ACR, COG1678
Tgr7_2911	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Tgr7_2912	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Tgr7_2913	COG0540	Belongs to the ATCase OTCase family
Tgr7_2915	COG0543	2 iron, 2 sulfur cluster binding
Tgr7_2924	COG0776	regulation of translation
Tgr7_2926	COG3785	DNA binding
Tgr7_2927	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
Tgr7_2930	COG1011	Hydrolase
Tgr7_2931	COG0494	nUDIX hydrolase
Tgr7_2932	COG1218	3'(2'),5'-bisphosphate nucleotidase
Tgr7_2933	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
Tgr7_2935	COG4067	protein conserved in archaea
Tgr7_2935	COG0189	ligase activity
Tgr7_2939	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Tgr7_2944	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
Tgr7_2945	COG1194	a g-specific adenine glycosylase
Tgr7_2950	COG0315	cyclic pyranopterin monophosphate synthase activity
Tgr7_2951	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Tgr7_2957	COG0071	Belongs to the small heat shock protein (HSP20) family
Tgr7_2959	COG1561	YicC-like family, N-terminal region
Tgr7_2960	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Tgr7_2961	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Tgr7_2963	COG0635	Involved in the biosynthesis of porphyrin-containing compound
Tgr7_2966	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Tgr7_2967	COG0254	rRNA binding
Tgr7_2969	COG0501	Belongs to the peptidase M48B family
Tgr7_2970	COG0281	malic enzyme
Tgr7_2971	COG0039	L-malate dehydrogenase activity
Tgr7_2983	COG3264	Mechanosensitive ion channel
Tgr7_2983	COG1511	domain protein
Tgr7_2984	COG2084	Dehydrogenase
Tgr7_2985	COG0742	ribosomal rna small subunit methyltransferase
Tgr7_2986	COG0612	Peptidase, M16
Tgr7_2987	COG0612	Peptidase, M16
Tgr7_2988	COG0552	protein localization to endoplasmic reticulum
Tgr7_2989	COG2884	Cell division ATP-binding protein ftsE
Tgr7_2990	COG2177	Part of the ABC transporter FtsEX involved in
Tgr7_2994	COG2217	Heavy metal translocating P-type atpase
Tgr7_2996	COG0348	domain, Protein
Tgr7_2997	COG2010	Cytochrome c
Tgr7_3000	COG3278	Belongs to the heme-copper respiratory oxidase family
Tgr7_3001	COG1612	heme a metabolic process
Tgr7_3002	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Tgr7_3003	COG0109	protoheme IX farnesyltransferase activity
Tgr7_3008	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
Tgr7_3010	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Tgr7_3011	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Tgr7_3013	COG2226	methyltransferase
Tgr7_3014	COG2267	carboxylic ester hydrolase activity
Tgr7_3015	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
Tgr7_3016	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Tgr7_3017	COG0828	Belongs to the bacterial ribosomal protein bS21 family
Tgr7_3018	COG1610	YqeY-like protein
Tgr7_3019	COG0493	'glutamate synthase
Tgr7_3020	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Tgr7_3025	COG3039	Transposase
Tgr7_3029	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Tgr7_3030	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Tgr7_3031	COG0232	Belongs to the dGTPase family. Type 2 subfamily
Tgr7_3033	COG0069	glutamate synthase activity
Tgr7_3033	COG0070	glutamate synthase
Tgr7_3033	COG0067	glutamate synthase
Tgr7_3035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Tgr7_3040	COG2267	carboxylic ester hydrolase activity
Tgr7_3042	COG3706	GGDEF domain
Tgr7_3048	COG0446	pyridine nucleotide-disulphide oxidoreductase
Tgr7_3051	COG1121	(ABC) transporter
Tgr7_3054	COG0735	belongs to the Fur family
Tgr7_3056	COG1192	Involved in chromosome partitioning
Tgr7_3057	COG1022	Amp-dependent synthetase and ligase
Tgr7_3058	COG1607	acyl-coa hydrolase
Tgr7_3059	COG2067	long-chain fatty acid transport protein
Tgr7_3061	COG0604	alcohol dehydrogenase
Tgr7_3063	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Tgr7_3063	COG1042	CoA-binding domain protein
Tgr7_3063	COG0045	succinate-CoA ligase (ADP-forming) activity
Tgr7_3068	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Tgr7_3069	COG2738	Putative neutral zinc metallopeptidase
Tgr7_3071	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Tgr7_3073	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Tgr7_3074	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Tgr7_3076	COG0583	DNA-binding transcription factor activity
Tgr7_3081	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
Tgr7_3083	COG1116	anion transmembrane transporter activity
Tgr7_3088	COG3665	Urea carboxylase-associated protein
Tgr7_3089	COG0439	Biotin carboxylase
Tgr7_3093	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Tgr7_3095	COG0463	Glycosyl transferase, family 2
Tgr7_3096	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Tgr7_3101	COG0829	nickel cation binding
Tgr7_3102	COG0831	urea catabolic process
Tgr7_3103	COG0832	Belongs to the urease beta subunit family
Tgr7_3104	COG0804	urea catabolic process
Tgr7_3105	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
Tgr7_3106	COG0830	nickel cation binding
Tgr7_3107	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
Tgr7_3117	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Tgr7_3119	COG0347	Belongs to the P(II) protein family
Tgr7_3120	COG0004	ammonium transporteR
Tgr7_3122	COG0390	transport system, permease component
Tgr7_3123	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
Tgr7_3124	COG1166	arginine decarboxylase activity
Tgr7_3126	COG3100	YcgL domain-containing protein
Tgr7_3129	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Tgr7_3134	COG0509	glycine decarboxylation via glycine cleavage system
Tgr7_3144	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
Tgr7_3147	COG2346	COG2346, Truncated hemoglobins
Tgr7_3156	COG2133	pyrroloquinoline quinone binding
Tgr7_3159	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
Tgr7_3164	COG0247	lactate metabolic process
Tgr7_3165	COG1139	Iron-sulfur cluster binding protein
Tgr7_3170	COG3384	dioxygenase
Tgr7_3174	COG1620	l-lactate permease
Tgr7_3176	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Tgr7_3178	COG0469	pyruvate kinase activity
Tgr7_3179	COG1515	deoxyribonuclease V activity
Tgr7_3180	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Tgr7_3183	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Tgr7_3185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Tgr7_3186	COG1758	RNA polymerase activity
Tgr7_3192	COG1192	Involved in chromosome partitioning
Tgr7_3194	COG2193	ferroxidase activity
Tgr7_3203	COG1850	ribulose-bisphosphate carboxylase activity
Tgr7_3205	COG0142	geranyltranstransferase activity
Tgr7_3206	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Tgr7_3207	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Tgr7_3208	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Tgr7_3209	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Tgr7_3210	COG0268	Binds directly to 16S ribosomal RNA
Tgr7_3215	COG0196	riboflavin kinase activity
Tgr7_3216	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Tgr7_3218	COG1047	Peptidyl-prolyl cis-trans
Tgr7_3219	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Tgr7_3236	COG2022	thiamine diphosphate biosynthetic process
Tgr7_3237	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Tgr7_3239	COG0471	metal ion transport
Tgr7_3239	COG3273	potassium ion transport
Tgr7_3243	COG0667	Aldo Keto reductase
Tgr7_3248	COG0084	hydrolase, TatD family'
Tgr7_3250	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
Tgr7_3251	COG5002	protein histidine kinase activity
Tgr7_3251	COG5001	Diguanylate cyclase
Tgr7_3255	COG0751	glycine-tRNA ligase activity
Tgr7_3258	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
Tgr7_3259	COG0174	glutamine synthetase
Tgr7_3261	COG3852	Histidine kinase
Tgr7_3262	COG2204	response regulator
Tgr7_3270	COG1459	type II secretion system
Tgr7_3271	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
Tgr7_3273	COG3267	Type II secretory pathway component ExeA
Tgr7_3273	COG3409	Peptidoglycan-binding domain 1 protein
Tgr7_3280	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Tgr7_3281	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Tgr7_3282	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
Tgr7_3285	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Tgr7_3286	COG0640	Transcriptional regulator
Tgr7_3287	COG4942	peptidase
Tgr7_3288	COG0793	Belongs to the peptidase S41A family
Tgr7_3289	COG2861	carbohydrate metabolic process
Tgr7_3290	COG0693	protein deglycase activity
Tgr7_3291	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
Tgr7_3302	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Tgr7_3303	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Tgr7_3304	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Tgr7_3305	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Tgr7_3306	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Tgr7_3307	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Tgr7_3308	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Tgr7_3309	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Tgr7_3311	COG0356	it plays a direct role in the translocation of protons across the membrane
Tgr7_3312	COG3312	ion transport
Tgr7_3313	COG1475	DNA binding
Tgr7_3314	COG1192	Involved in chromosome partitioning
Tgr7_3315	COG0357	Ribosomal RNA small subunit methyltransferase G
Tgr7_3316	COG0445	tRNA wobble uridine modification
Tgr7_3317	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
Tgr7_3318	COG0706	membrane insertase activity
Tgr7_3319	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
Tgr7_3320	COG0594	ribonuclease P activity
Tgr7_3321	COG0230	Belongs to the bacterial ribosomal protein bL34 family