locus-tag	class	description
LT988_00010	COG3258	Cytochrome c
LT988_00015	COG4716	Myosin-crossreactive antigen
LT988_00020	COG1858	cytochrome C peroxidase
LT988_00065	COG3344	reverse transcriptase
LT988_00090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LT988_00095	COG1129	ABC transporter
LT988_00095	COG0842	Transport permease protein
LT988_00100	COG0842	Transport permease protein
LT988_00110	COG0071	Belongs to the small heat shock protein (HSP20) family
LT988_00120	COG0406	alpha-ribazole phosphatase activity
LT988_00125	COG4716	Myosin-crossreactive antigen
LT988_00190	COG1047	Peptidyl-prolyl cis-trans
LT988_00200	COG1047	Peptidyl-prolyl cis-trans
LT988_00230	COG0398	Pfam SNARE associated Golgi protein
LT988_00250	COG1331	Highly conserved protein containing a thioredoxin domain
LT988_00255	COG3220	belongs to the UPF0276 family
LT988_00270	COG3527	Alpha-acetolactate decarboxylase
LT988_00305	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LT988_00325	COG3954	Phosphoribulokinase
LT988_00350	COG0310	cobalt ion transport
LT988_00360	COG1122	ATPase activity
LT988_00385	COG4372	Transposase
LT988_00390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LT988_00400	COG3258	Cytochrome c
LT988_00415	COG1763	Mo-molybdopterin cofactor biosynthetic process
LT988_00420	COG0488	(ABC) transporter
LT988_00425	COG5002	protein histidine kinase activity
LT988_00425	COG5001	Diguanylate cyclase
LT988_00445	COG0668	transmembrane transport
LT988_00455	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LT988_00465	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LT988_00475	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LT988_00485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LT988_00490	COG3909	cytochrome
LT988_00520	COG2066	Belongs to the glutaminase family
LT988_00520	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LT988_00525	COG2226	methyltransferase
LT988_00530	COG1040	competence protein
LT988_00535	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LT988_00550	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LT988_00605	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LT988_00610	COG3005	denitrification pathway
LT988_00620	COG2863	cytochrome
LT988_00625	COG0446	pyridine nucleotide-disulphide oxidoreductase
LT988_00650	COG1320	monovalent cation:proton antiporter activity
LT988_00670	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LT988_00675	COG0651	ATP synthesis coupled electron transport
LT988_00745	COG0542	response to heat
LT988_00770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LT988_00780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LT988_00800	COG0628	permease
LT988_00820	COG2205	protein histidine kinase activity
LT988_00820	COG2198	Histidine kinase
LT988_00820	COG0784	Response regulator, receiver
LT988_00825	COG1546	Belongs to the CinA family
LT988_00825	COG1058	Belongs to the CinA family
LT988_00830	COG1185	polyribonucleotide nucleotidyltransferase activity
LT988_00835	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LT988_00840	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LT988_00845	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LT988_00850	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LT988_00855	COG0195	Participates in both transcription termination and antitermination
LT988_00885	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
LT988_00890	COG1472	Belongs to the glycosyl hydrolase 3 family
LT988_00905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LT988_00910	COG0424	maF-like protein
LT988_00915	COG0741	lytic transglycosylase activity
LT988_00915	COG0739	heme binding
LT988_00915	COG1196	nuclear chromosome segregation
LT988_00925	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LT988_00925	COG1042	CoA-binding domain protein
LT988_00925	COG0045	succinate-CoA ligase (ADP-forming) activity
LT988_00930	COG0123	including yeast histone deacetylase and acetoin utilization protein
LT988_00940	COG0415	Belongs to the DNA photolyase family
LT988_00945	COG0084	hydrolase, TatD family'
LT988_00955	COG3122	Protein conserved in bacteria
LT988_00970	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LT988_00985	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LT988_00995	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LT988_01025	COG0469	pyruvate kinase activity
LT988_01060	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LT988_01090	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
LT988_01130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LT988_01135	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LT988_01140	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LT988_01165	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LT988_01175	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LT988_01180	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LT988_01195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LT988_01200	COG1444	tRNA N-acetyltransferase activity
LT988_01210	COG3132	Protein of unknown function, DUF480
LT988_01220	COG0670	Belongs to the BI1 family
LT988_01240	COG1301	dicarboxylic acid transport
LT988_01250	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LT988_01255	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LT988_01265	COG1272	protein, Hemolysin III
LT988_01270	COG1902	pentaerythritol trinitrate reductase activity
LT988_01285	COG2814	Major facilitator Superfamily
LT988_01330	COG0617	tRNA 3'-terminal CCA addition
LT988_01360	COG0589	response to stress
LT988_01365	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LT988_01375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LT988_01395	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LT988_01395	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LT988_01400	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LT988_01405	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LT988_01415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LT988_01425	COG1028	Short-chain dehydrogenase reductase Sdr
LT988_01430	COG0156	8-amino-7-oxononanoate synthase activity
LT988_01435	COG0596	Alpha beta hydrolase
LT988_01440	COG2226	methyltransferase
LT988_01450	COG2027	D-alanyl-D-alanine carboxypeptidase
LT988_01455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LT988_01460	COG1131	(ABC) transporter
LT988_01485	COG0359	binds to the 23S rRNA
LT988_01500	COG0360	Binds together with S18 to 16S ribosomal RNA
LT988_01510	COG2755	lipolytic protein G-D-S-L family
LT988_01510	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
LT988_01525	COG1199	ATP-dependent helicase activity
LT988_01535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LT988_01540	COG0842	Transport permease protein
LT988_01545	COG1131	(ABC) transporter
LT988_01550	COG0730	response to heat
LT988_01560	COG3453	Protein conserved in bacteria
LT988_01560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LT988_01570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LT988_01585	COG1666	GTP binding
LT988_01590	COG4974	Belongs to the 'phage' integrase family
LT988_01600	COG2983	Belongs to the UPF0260 family
LT988_01605	COG0189	ligase activity
LT988_01610	COG0826	peptidase U32
LT988_01625	COG1874	Beta-galactosidase
LT988_01625	COG0366	Alpha amylase catalytic
LT988_01630	COG0628	permease
LT988_01635	COG3128	pkhd-type hydroxylase
LT988_01650	COG0471	metal ion transport
LT988_01650	COG3273	potassium ion transport
LT988_01690	COG4133	protoheme IX ABC transporter activity
LT988_01695	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LT988_01700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LT988_01710	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LT988_01720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LT988_01725	COG3088	subunit of a heme lyase
LT988_01735	COG1881	PFAM PEBP family protein
LT988_01740	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LT988_01755	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LT988_01815	COG2010	Cytochrome c
LT988_01825	COG4783	chaperone-mediated protein folding
LT988_01835	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LT988_01840	COG0484	heat shock protein binding
LT988_01845	COG0443	Heat shock 70 kDa protein
LT988_01850	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LT988_01855	COG1420	regulation of RNA biosynthetic process
LT988_01860	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LT988_01865	COG0497	DNA recombination
LT988_01870	COG3547	Transposase (IS116 IS110 IS902 family)
LT988_01885	COG2974	May be involved in recombination
LT988_01890	COG4536	flavin adenine dinucleotide binding
LT988_01900	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LT988_01905	COG0644	oxidoreductase
LT988_01910	COG2354	Protein conserved in bacteria
LT988_01935	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LT988_01940	COG0589	response to stress
LT988_01955	COG1346	cytolysis
LT988_01965	COG1363	Peptidase, m42
LT988_01970	COG0189	ligase activity
LT988_01970	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LT988_01975	COG0367	asparagine synthase
LT988_01980	COG0302	gtp cyclohydrolase
LT988_02020	COG2026	Addiction module toxin, RelE StbE family
LT988_02065	COG4969	Belongs to the N-Me-Phe pilin family
LT988_02090	COG0438	transferase activity, transferring glycosyl groups
LT988_02105	COG2226	methyltransferase
LT988_02110	COG0438	transferase activity, transferring glycosyl groups
LT988_02135	COG3267	Type II secretory pathway component ExeA
LT988_02135	COG3409	Peptidoglycan-binding domain 1 protein
LT988_02155	COG0438	transferase activity, transferring glycosyl groups
LT988_02185	COG3550	peptidyl-serine autophosphorylation
LT988_02200	COG3549	Plasmid maintenance system killer
LT988_02250	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
LT988_02275	COG1394	ATPase activity, coupled to movement of substances
LT988_02280	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
LT988_02285	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
LT988_02305	COG1269	ATP hydrolysis coupled proton transport
LT988_02330	COG1269	ATP hydrolysis coupled proton transport
LT988_02345	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
LT988_02350	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
LT988_02355	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
LT988_02375	COG0602	queuosine metabolic process
LT988_02380	COG0720	synthase
LT988_02385	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LT988_02415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LT988_02420	COG0297	glycogen (starch) synthase activity
LT988_02425	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LT988_02430	COG3737	Protein of unknown function (DUF498/DUF598)
LT988_02450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LT988_02480	COG0142	geranyltranstransferase activity
LT988_02485	COG1469	GTP cyclohydrolase I activity
LT988_02510	COG1394	ATPase activity, coupled to movement of substances
LT988_02525	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LT988_02530	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LT988_02560	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LT988_02565	COG0321	lipoyl(octanoyl) transferase activity
LT988_02565	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LT988_02570	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LT988_02575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LT988_02580	COG1007	ATP synthesis coupled electron transport
LT988_02595	COG0713	ATP synthesis coupled electron transport
LT988_02605	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LT988_02610	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LT988_02620	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LT988_02630	COG0649	NAD binding
LT988_02635	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LT988_02640	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LT988_02645	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LT988_02660	COG0149	triose-phosphate isomerase activity
LT988_02665	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LT988_02705	COG4942	peptidase
LT988_02735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LT988_02835	COG0628	permease
LT988_02840	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LT988_02880	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
LT988_02890	COG4117	Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein)
LT988_02915	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
LT988_02930	COG1773	rubredoxin
LT988_02940	COG2204	response regulator
LT988_02970	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LT988_03010	COG2862	Uncharacterized protein family, UPF0114
LT988_03020	COG2833	Protein of unknown function (DUF455)
LT988_03025	COG2379	hydroxypyruvate reductase
LT988_03035	COG1214	PFAM Peptidase M22, glycoprotease
LT988_03060	COG3409	Peptidoglycan-binding domain 1 protein
LT988_03060	COG3267	Type II secretory pathway component ExeA
LT988_03075	COG2333	competence protein COMEC
LT988_03075	COG0658	competence protein
LT988_03085	COG1136	(ABC) transporter
LT988_03090	COG4591	ABC-type transport system involved in lipoprotein release permease component
LT988_03120	COG2957	Belongs to the agmatine deiminase family
LT988_03145	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
LT988_03150	COG1162	GTPase activity
LT988_03155	COG1690	Belongs to the RtcB family
LT988_03180	COG3956	TIGRFAM MazG family protein
LT988_03190	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LT988_03220	COG1301	dicarboxylic acid transport
LT988_03250	COG0277	FAD linked oxidase domain protein
LT988_03255	COG1242	4 iron, 4 sulfur cluster binding
LT988_03260	COG0826	peptidase U32
LT988_03265	COG0826	peptidase U32
LT988_03270	COG3154	lipid carrier protein
LT988_03275	COG0741	lytic transglycosylase activity
LT988_03285	COG3409	Peptidoglycan-binding domain 1 protein
LT988_03285	COG3267	Type II secretory pathway component ExeA
LT988_03290	COG0463	Glycosyl transferase, family 2
LT988_03290	COG1216	Glycosyl transferase, family 2
LT988_03310	COG0579	oxidoreductase
LT988_03335	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LT988_03340	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LT988_03345	COG1132	(ABC) transporter
LT988_03375	COG0438	transferase activity, transferring glycosyl groups
LT988_03410	COG0438	transferase activity, transferring glycosyl groups
LT988_03420	COG1216	Glycosyl transferase, family 2
LT988_03450	COG0438	transferase activity, transferring glycosyl groups
LT988_03500	COG0438	transferase activity, transferring glycosyl groups
LT988_03505	COG2226	methyltransferase
LT988_03525	COG3409	Peptidoglycan-binding domain 1 protein
LT988_03525	COG3267	Type II secretory pathway component ExeA
LT988_03550	COG1132	(ABC) transporter
LT988_03575	COG1215	transferase activity, transferring glycosyl groups
LT988_03610	COG1610	YqeY-like protein
LT988_03615	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LT988_03635	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LT988_03650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LT988_03665	COG0583	DNA-binding transcription factor activity
LT988_03675	COG2210	Belongs to the sulfur carrier protein TusA family
LT988_03680	COG0425	Belongs to the sulfur carrier protein TusA family
LT988_03685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LT988_03690	COG1648	precorrin-2 dehydrogenase activity
LT988_03690	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LT988_03695	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LT988_03700	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LT988_03745	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LT988_03755	COG0531	amino acid
LT988_03760	COG5654	RES domain protein
LT988_03765	COG5642	Protein of unknown function (DUF2384)
LT988_03770	COG1187	pseudouridine synthase activity
LT988_03775	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LT988_03780	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LT988_03785	COG0180	Tryptophanyl-tRNA synthetase
LT988_03790	COG1994	Peptidase M50
LT988_03795	COG0009	L-threonylcarbamoyladenylate synthase
LT988_03800	COG0613	PHP domain protein
LT988_03835	COG1918	ferrous iron import across plasma membrane
LT988_03840	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
LT988_03850	COG1230	cation diffusion facilitator family transporter
LT988_03860	COG3008	intermembrane lipid transfer
LT988_03865	COG2995	paraquat-inducible protein a
LT988_03875	COG2920	part of a sulfur-relay system
LT988_03890	COG1720	tRNA m6t6A37 methyltransferase activity
LT988_03895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LT988_03900	COG0557	exoribonuclease II activity
LT988_03920	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
LT988_03925	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
LT988_03940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LT988_03955	COG0730	response to heat
LT988_03980	COG1342	Belongs to the UPF0251 family
LT988_03990	COG1234	tRNA 3'-trailer cleavage
LT988_04005	COG1511	domain protein
LT988_04005	COG3264	Mechanosensitive ion channel
LT988_04025	COG1301	dicarboxylic acid transport
LT988_04030	COG1028	Short-chain dehydrogenase reductase Sdr
LT988_04050	COG2925	Exonuclease
LT988_04060	COG0336	Belongs to the RNA methyltransferase TrmD family
LT988_04065	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LT988_04070	COG0228	four-way junction DNA binding
LT988_04090	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LT988_04110	COG0038	chloride channel
LT988_04120	COG1388	LysM domain
LT988_04120	COG1705	Flagellar rod assembly protein muramidase FlgJ
LT988_04135	COG1511	domain protein
LT988_04135	COG3264	Mechanosensitive ion channel
LT988_04170	COG4932	domain protein
LT988_04170	COG1388	LysM domain
LT988_04190	COG0786	glutamate:sodium symporter activity
LT988_04200	COG2995	paraquat-inducible protein a
LT988_04205	COG3008	intermembrane lipid transfer
LT988_04205	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LT988_04215	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
LT988_04220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LT988_04270	COG2166	iron-sulfur cluster assembly
LT988_04275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LT988_04280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LT988_04285	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LT988_04295	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LT988_04300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LT988_04305	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LT988_04315	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LT988_04335	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LT988_04340	COG0233	cytoplasmic translational termination
LT988_04345	COG0528	UMP kinase activity
LT988_04350	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LT988_04355	COG0052	Belongs to the universal ribosomal protein uS2 family
LT988_04360	COG0024	Methionine aminopeptidase
LT988_04365	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LT988_04380	COG0436	Aminotransferase
LT988_04385	COG2171	N-acyltransferase activity
LT988_04390	COG1393	Belongs to the ArsC family
LT988_04395	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LT988_04400	COG1942	4-Oxalocrotonate Tautomerase
LT988_04410	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
LT988_04415	COG0402	S-adenosylhomocysteine deaminase activity
LT988_04420	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LT988_04425	COG3409	Peptidoglycan-binding domain 1 protein
LT988_04425	COG0860	N-Acetylmuramoyl-L-alanine amidase
LT988_04430	COG2719	SpoVR family
LT988_04435	COG2718	Belongs to the UPF0229 family
LT988_04440	COG2766	serine protein kinase
LT988_04445	COG0166	Belongs to the GPI family
LT988_04450	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LT988_04455	COG0297	glycogen (starch) synthase activity
LT988_04460	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
LT988_04465	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LT988_04470	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LT988_04475	COG0617	tRNA 3'-terminal CCA addition
LT988_04485	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LT988_04490	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LT988_04525	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LT988_04545	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LT988_04550	COG4974	Belongs to the 'phage' integrase family
LT988_04585	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
LT988_04610	COG1858	cytochrome C peroxidase
LT988_04615	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LT988_04620	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LT988_04625	COG1053	succinate dehydrogenase
LT988_04630	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LT988_04645	COG1560	Kdo2-lipid A biosynthetic process
LT988_04670	COG0837	glucose binding
LT988_04695	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LT988_04715	COG0864	Transcriptional regulator
LT988_04730	COG2308	Evidence 4 Homologs of previously reported genes of
LT988_04740	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LT988_04745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LT988_04765	COG1960	acyl-CoA dehydrogenase activity
LT988_04770	COG0183	Belongs to the thiolase family
LT988_04775	COG1024	Enoyl-CoA hydratase
LT988_04775	COG1250	3-hydroxyacyl-CoA dehydrogenase
LT988_04810	COG0012	GTP binding
LT988_04815	COG0662	Cupin 2, conserved barrel domain protein
LT988_04815	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LT988_04820	COG0483	inositol monophosphate 1-phosphatase activity
LT988_04835	COG0582	viral genome integration into host DNA
LT988_04855	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LT988_04960	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LT988_04975	COG5001	Diguanylate cyclase
LT988_04975	COG5002	protein histidine kinase activity
LT988_04980	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LT988_04990	COG0584	glycerophosphoryl diester phosphodiesterase
LT988_05030	COG3344	reverse transcriptase
LT988_05040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LT988_05040	COG4191	Histidine kinase
LT988_05055	COG1192	Involved in chromosome partitioning
LT988_05080	COG0038	chloride channel
LT988_05110	COG1857	crispr-associated protein
LT988_05130	COG1518	maintenance of DNA repeat elements
LT988_05135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LT988_05155	COG2716	regulation of RNA biosynthetic process
LT988_05160	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LT988_05165	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LT988_05210	COG0347	Belongs to the P(II) protein family
LT988_05220	COG0659	secondary active sulfate transmembrane transporter activity
LT988_05250	COG2373	Large extracellular alpha-helical protein
LT988_05265	COG0686	Belongs to the AlaDH PNT family
LT988_05280	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
LT988_05285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LT988_05315	COG4453	Protein conserved in bacteria
LT988_05350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LT988_05355	COG1074	ATP-dependent DNA helicase activity
LT988_05360	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LT988_05380	COG0735	belongs to the Fur family
LT988_05385	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LT988_05395	COG0803	Belongs to the bacterial solute-binding protein 9 family
LT988_05395	COG3443	Belongs to the bacterial solute-binding protein 9 family
LT988_05405	COG2119	membrane
LT988_05430	COG0477	Major facilitator Superfamily
LT988_05440	COG0511	ligase activity, forming carbon-carbon bonds
LT988_05440	COG5016	pyruvate
LT988_05445	COG0439	Biotin carboxylase
LT988_05470	COG0700	Nucleoside recognition
LT988_05485	COG4115	mRNA cleavage
LT988_05490	COG2161	toxin-antitoxin pair type II binding
LT988_05500	COG3549	Plasmid maintenance system killer
LT988_05595	COG1414	Transcriptional regulator
LT988_05600	COG0714	Associated with various cellular activities
LT988_05620	COG2304	oxidoreductase activity
LT988_05635	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LT988_05640	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LT988_05650	COG0651	ATP synthesis coupled electron transport
LT988_05665	COG1320	monovalent cation:proton antiporter activity
LT988_05700	COG4566	intracellular signal transduction
LT988_05710	COG1487	ribonuclease activity
LT988_05725	COG2235	arginine
LT988_05740	COG0628	permease
LT988_05760	COG4413	Urea transporter
LT988_05765	COG2235	arginine
LT988_05795	COG0577	efflux transmembrane transporter activity
LT988_05795	COG1136	(ABC) transporter
LT988_05820	COG1269	ATP hydrolysis coupled proton transport
LT988_05840	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
LT988_05860	COG1295	ribonuclease BN
LT988_05905	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LT988_05920	COG4191	Histidine kinase
LT988_05925	COG4566	intracellular signal transduction
LT988_05940	COG3119	arylsulfatase activity
LT988_05945	COG0791	NLP P60 protein
LT988_05945	COG1388	LysM domain
LT988_05975	COG3119	arylsulfatase activity
LT988_05985	COG0741	lytic transglycosylase activity
LT988_05985	COG1388	LysM domain
LT988_06010	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LT988_06010	COG2010	Cytochrome c
LT988_06045	COG1566	PFAM secretion protein HlyD family protein
LT988_06070	COG0475	glutathione-regulated potassium exporter activity
LT988_06085	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LT988_06090	COG2326	polyphosphate kinase activity
LT988_06115	COG0668	transmembrane transport
LT988_06125	COG0598	Magnesium transport protein CorA
LT988_06145	COG0500	methyltransferase
LT988_06150	COG3852	Histidine kinase
LT988_06155	COG2204	response regulator
LT988_06165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LT988_06180	COG3177	Filamentation induced by cAMP protein fic
LT988_06185	COG1566	PFAM secretion protein HlyD family protein
LT988_06190	COG2814	Major facilitator Superfamily
LT988_06200	COG0475	glutathione-regulated potassium exporter activity
LT988_06205	COG3158	transport of potassium into the cell
LT988_06215	COG0500	methyltransferase
LT988_06225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LT988_06250	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LT988_06275	COG0446	pyridine nucleotide-disulphide oxidoreductase
LT988_06285	COG0446	pyridine nucleotide-disulphide oxidoreductase
LT988_06290	COG0589	response to stress
LT988_06320	COG0028	Belongs to the TPP enzyme family
LT988_06350	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LT988_06375	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LT988_06390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LT988_06400	COG0471	metal ion transport
LT988_06400	COG3273	potassium ion transport
LT988_06405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LT988_06460	COG1643	Atp-dependent helicase
LT988_06490	COG0616	signal peptide processing
LT988_06495	COG0546	phosphoglycolate phosphatase activity
LT988_06500	COG0564	pseudouridine synthase activity
LT988_06505	COG1530	ribonuclease E activity
LT988_06525	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LT988_06535	COG0438	transferase activity, transferring glycosyl groups
LT988_06540	COG0561	phosphatase activity
LT988_06540	COG3100	YcgL domain-containing protein
LT988_06545	COG1105	Belongs to the carbohydrate kinase PfkB family
LT988_06555	COG0616	signal peptide processing
LT988_06570	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LT988_06575	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LT988_06580	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LT988_06605	COG1797	cobyrinic acid a,c-diamide synthase activity
LT988_06640	COG2920	part of a sulfur-relay system
LT988_06645	COG2168	tRNA wobble position uridine thiolation
LT988_06650	COG2923	Belongs to the DsrF TusC family
LT988_06655	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LT988_06660	COG2221	Nitrite and sulphite reductase 4Fe-4S
LT988_06665	COG2221	Nitrite and sulphite reductase 4Fe-4S
LT988_06690	COG2920	part of a sulfur-relay system
LT988_06700	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LT988_06715	COG2204	response regulator
LT988_06740	COG2814	Major facilitator Superfamily
LT988_06790	COG2193	ferroxidase activity
LT988_06825	COG1131	(ABC) transporter
LT988_06845	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LT988_06905	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LT988_06910	COG0058	SHG alpha-glucan phosphorylase activity
LT988_06925	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
LT988_06935	COG5002	protein histidine kinase activity
LT988_06940	COG0745	RESPONSE REGULATOR receiver
LT988_06960	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LT988_06980	COG4206	TonB-dependent receptor
LT988_06995	COG2095	MarC family integral membrane protein
LT988_07015	COG2326	polyphosphate kinase activity
LT988_07030	COG3706	GGDEF domain
LT988_07035	COG1607	acyl-coa hydrolase
LT988_07045	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
LT988_07055	COG0009	L-threonylcarbamoyladenylate synthase
LT988_07065	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LT988_07070	COG0659	secondary active sulfate transmembrane transporter activity
LT988_07075	COG1850	ribulose-bisphosphate carboxylase activity
LT988_07080	COG4451	ribulose bisphosphate carboxylase, small
LT988_07105	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
LT988_07110	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
LT988_07130	COG0583	DNA-binding transcription factor activity
LT988_07135	COG0406	alpha-ribazole phosphatase activity
LT988_07140	COG0435	Glutathione S-transferase
LT988_07175	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LT988_07195	COG4372	Transposase
LT988_07215	COG4372	Transposase
LT988_07300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LT988_07325	COG0668	transmembrane transport
LT988_07385	COG4372	Transposase
LT988_07400	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LT988_07410	COG4636	protein conserved in cyanobacteria
LT988_07420	COG1205	dead DEAH box helicase
LT988_07420	COG1111	helicase
LT988_07425	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LT988_07455	COG2135	peptidase activity
LT988_07465	COG1012	belongs to the aldehyde dehydrogenase family
LT988_07485	COG3012	SEC-C Motif Domain Protein
LT988_07490	COG2205	protein histidine kinase activity
LT988_07490	COG0784	Response regulator, receiver
LT988_07505	COG1902	pentaerythritol trinitrate reductase activity
LT988_07600	COG4969	Belongs to the N-Me-Phe pilin family
LT988_07635	COG1063	alcohol dehydrogenase
LT988_07695	COG0348	domain, Protein
LT988_07700	COG0437	4 iron, 4 sulfur cluster binding
LT988_07705	COG0243	molybdopterin cofactor binding
LT988_07730	COG1116	anion transmembrane transporter activity
LT988_07730	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LT988_07755	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LT988_07775	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LT988_07790	COG0668	transmembrane transport
LT988_07845	COG0076	glutamate decarboxylase activity
LT988_07855	COG3609	addiction module antidote protein, CC2985 family
LT988_07920	COG4974	Belongs to the 'phage' integrase family
LT988_07925	COG0582	viral genome integration into host DNA
LT988_07930	COG4974	Belongs to the 'phage' integrase family
LT988_07935	COG4372	Transposase
LT988_07990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LT988_08010	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LT988_08025	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LT988_08030	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LT988_08035	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LT988_08045	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LT988_08050	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LT988_08060	COG0126	phosphoglycerate kinase activity
LT988_08065	COG0469	pyruvate kinase activity
LT988_08085	COG0259	pyridoxamine-phosphate oxidase activity
LT988_08120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LT988_08125	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
LT988_08145	COG4907	membrane protein (DUF2207)
LT988_08150	COG1704	LemA family
LT988_08155	COG0741	lytic transglycosylase activity
LT988_08165	COG0688	phosphatidylethanolamine metabolic process
LT988_08190	COG4067	protein conserved in archaea
LT988_08190	COG0189	ligase activity
LT988_08200	COG2308	Evidence 4 Homologs of previously reported genes of
LT988_08215	COG5002	protein histidine kinase activity
LT988_08215	COG2205	protein histidine kinase activity
LT988_08215	COG0784	Response regulator, receiver
LT988_08220	COG1295	ribonuclease BN
LT988_08225	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LT988_08230	COG0513	Belongs to the DEAD box helicase family
LT988_08255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LT988_08410	COG2918	glutathione biosynthetic process
LT988_08415	COG0793	Belongs to the peptidase S41A family
LT988_08420	COG0242	peptide deformylase activity
LT988_08425	COG3830	Belongs to the UPF0237 family
LT988_08445	COG0347	Belongs to the P(II) protein family
LT988_08455	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LT988_08460	COG0045	succinate-CoA ligase (ADP-forming) activity
LT988_08475	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LT988_08475	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LT988_08480	COG3264	Mechanosensitive ion channel
LT988_08480	COG1511	domain protein
LT988_08495	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LT988_08505	COG4681	YaeQ
LT988_08515	COG0284	orotidine-5'-phosphate decarboxylase activity
LT988_08520	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LT988_08545	COG1283	sodium-dependent phosphate transmembrane transporter activity
LT988_08550	COG1022	Amp-dependent synthetase and ligase
LT988_08590	COG1132	(ABC) transporter
LT988_08595	COG0517	IMP dehydrogenase activity
LT988_08600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LT988_08605	COG4279	zinc finger
LT988_08635	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LT988_08655	COG0300	oxidoreductase activity
LT988_08660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LT988_08665	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LT988_08670	COG0505	Belongs to the CarA family
LT988_08680	COG3118	belongs to the thioredoxin family
LT988_08685	COG0037	tRNA processing
LT988_08690	COG0825	malonyl-CoA metabolic process
LT988_08705	COG0577	efflux transmembrane transporter activity
LT988_08705	COG1136	(ABC) transporter
LT988_08730	COG1570	exodeoxyribonuclease VII activity
LT988_08735	COG0517	IMP dehydrogenase activity
LT988_08735	COG0516	GMP reductase activity
LT988_08740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LT988_08740	COG0519	Catalyzes the synthesis of GMP from XMP
LT988_08795	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LT988_08805	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LT988_08815	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LT988_08830	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LT988_08835	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LT988_08840	COG1850	ribulose-bisphosphate carboxylase activity
LT988_08895	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
LT988_08900	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
LT988_08905	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
LT988_08910	COG1063	alcohol dehydrogenase
LT988_08915	COG0500	methyltransferase
LT988_08920	COG0142	geranyltranstransferase activity
LT988_08940	COG1719	4-vinyl reductase, 4VR
LT988_08945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LT988_08980	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
LT988_08985	COG1429	ligase activity, forming nitrogen-metal bonds
LT988_08990	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
LT988_08995	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
LT988_09010	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LT988_09015	COG0644	oxidoreductase
LT988_09025	COG4251	negative regulation of phosphorylation
LT988_09040	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
LT988_09045	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
LT988_09045	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
LT988_09055	COG0724	RNA recognition motif
LT988_09060	COG0513	Belongs to the DEAD box helicase family
LT988_09075	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LT988_09080	COG3876	Protein conserved in bacteria
LT988_09085	COG2205	protein histidine kinase activity
LT988_09090	COG0745	RESPONSE REGULATOR receiver
LT988_09095	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LT988_09135	COG2084	Dehydrogenase
LT988_09140	COG0247	lactate metabolic process
LT988_09145	COG0277	FAD linked oxidase domain protein
LT988_09150	COG0632	four-way junction helicase activity
LT988_09155	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LT988_09160	COG0217	transcriptional regulatory protein
LT988_09175	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
LT988_09185	COG0494	nUDIX hydrolase
LT988_09190	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LT988_09195	COG0653	protein targeting
LT988_09200	COG0739	heme binding
LT988_09210	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LT988_09225	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LT988_09230	COG1181	Belongs to the D-alanine--D-alanine ligase family
LT988_09235	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LT988_09240	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LT988_09245	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LT988_09250	COG0772	Belongs to the SEDS family
LT988_09255	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LT988_09260	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LT988_09265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LT988_09280	COG3116	cell division
LT988_09285	COG0275	rRNA processing
LT988_09290	COG2001	Belongs to the MraZ family
LT988_09300	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LT988_09310	COG0792	nuclease activity
LT988_09315	COG2823	Periplasmic or secreted lipoprotein
LT988_09320	COG0277	FAD linked oxidase domain protein
LT988_09325	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
LT988_09330	COG0494	nUDIX hydrolase
LT988_09365	COG1573	uracil-dna glycosylase
LT988_09370	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LT988_09415	COG1183	phosphatidylcholine synthase activity
LT988_09420	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LT988_09435	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
LT988_09445	COG3259	Nickel-dependent hydrogenase
LT988_09470	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LT988_09480	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LT988_09510	COG2814	Major facilitator Superfamily
LT988_09520	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LT988_09535	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
LT988_09540	COG1116	anion transmembrane transporter activity
LT988_09545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LT988_09550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LT988_09585	COG0514	ATP-dependent DNA helicase (RecQ)
LT988_09590	COG0248	Ppx GppA phosphatase
LT988_09600	COG1028	Short-chain dehydrogenase reductase Sdr
LT988_09635	COG2154	pterin-4-alpha-carbinolamine dehydratase
LT988_09645	COG0704	Plays a role in the regulation of phosphate uptake
LT988_09650	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LT988_09660	COG0573	inorganic phosphate transmembrane transporter activity
LT988_09675	COG0438	transferase activity, transferring glycosyl groups
LT988_09680	COG0717	Belongs to the dCTP deaminase family
LT988_09690	COG0489	protein tyrosine kinase activity
LT988_09695	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LT988_09695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LT988_09700	COG4657	Part of a membrane complex involved in electron transport
LT988_09705	COG2878	Part of a membrane complex involved in electron transport
LT988_09715	COG4658	electron transport chain
LT988_09725	COG4660	Part of a membrane complex involved in electron transport
LT988_09735	COG3954	Phosphoribulokinase
LT988_09740	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LT988_09750	COG4535	Mg2 and Co2 transporter CorC
LT988_09755	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LT988_09775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LT988_09815	COG4263	nitrous-oxide reductase activity
LT988_09840	COG0437	4 iron, 4 sulfur cluster binding
LT988_09845	COG0348	domain, Protein
LT988_09850	COG1121	(ABC) transporter
LT988_09880	COG0732	type I restriction modification DNA specificity domain
LT988_09900	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LT988_09910	COG0436	Aminotransferase
LT988_09930	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LT988_09935	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LT988_09960	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LT988_09965	COG1053	succinate dehydrogenase
LT988_09970	COG2009	succinate dehydrogenase
LT988_09975	COG0037	tRNA processing
LT988_09985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LT988_09985	COG4221	oxidoreductase activity
LT988_09985	COG0604	alcohol dehydrogenase
LT988_09985	COG3321	synthase
LT988_09990	COG3153	acetyltransferase
LT988_09990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LT988_10010	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LT988_10010	COG0512	Glutamine amidotransferase of anthranilate synthase
LT988_10015	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LT988_10020	COG0071	Belongs to the small heat shock protein (HSP20) family
LT988_10025	COG0318	PFAM AMP-dependent synthetase and ligase
LT988_10025	COG0204	Acyl-transferase
LT988_10030	COG2814	Major facilitator Superfamily
LT988_10050	COG0824	Thioesterase
LT988_10060	COG4145	pantothenate transmembrane transporter activity
LT988_10115	COG0298	carbon dioxide binding
LT988_10120	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LT988_10135	COG4991	sh3 domain protein
LT988_10145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LT988_10245	COG0367	asparagine synthase
LT988_10255	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LT988_10270	COG0418	dihydroorotase activity
LT988_10285	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LT988_10290	COG0676	glucose-6-phosphate 1-epimerase activity
LT988_10305	COG0415	Belongs to the DNA photolyase family
LT988_10320	COG0071	Belongs to the small heat shock protein (HSP20) family
LT988_10325	COG0071	Belongs to the small heat shock protein (HSP20) family
LT988_10335	COG4191	Histidine kinase
LT988_10350	COG0589	response to stress
LT988_10355	COG0347	Belongs to the P(II) protein family
LT988_10370	COG3030	protein affecting phage T7 exclusion by the F plasmid
LT988_10375	COG1324	tolerance protein
LT988_10380	COG4232	protein-disulfide reductase activity
LT988_10385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LT988_10400	COG0439	Biotin carboxylase
LT988_10410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LT988_10420	COG0138	bifunctional purine biosynthesis protein purh
LT988_10425	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LT988_10430	COG0151	Belongs to the GarS family
LT988_10435	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LT988_10525	COG2801	Transposase and inactivated derivatives
LT988_10545	COG1028	Short-chain dehydrogenase reductase Sdr
LT988_10570	COG3243	poly(R)-hydroxyalkanoic acid synthase
LT988_10590	COG0714	Associated with various cellular activities
LT988_10605	COG0321	lipoyl(octanoyl) transferase activity
LT988_10610	COG2921	Belongs to the UPF0250 family
LT988_10615	COG1686	Belongs to the peptidase S11 family
LT988_10620	COG2951	lytic endotransglycosylase activity
LT988_10625	COG0772	Belongs to the SEDS family
LT988_10630	COG0768	penicillin binding
LT988_10640	COG1792	Involved in formation and maintenance of cell shape
LT988_10645	COG1077	Cell shape determining protein MreB Mrl
LT988_10650	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LT988_10660	COG3344	reverse transcriptase
LT988_10725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LT988_10760	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LT988_10795	COG3604	Transcriptional regulator
LT988_10805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LT988_10805	COG1017	nitric oxide dioxygenase activity
LT988_10815	COG1335	isochorismatase
LT988_10850	COG0596	Alpha beta hydrolase
LT988_10880	COG0589	response to stress
LT988_10925	COG1858	cytochrome C peroxidase
LT988_10955	COG2249	NAD(P)H dehydrogenase (quinone) activity
LT988_10965	COG2363	Small membrane protein
LT988_10970	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LT988_10985	COG0189	ligase activity
LT988_10995	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LT988_11000	COG1678	Uncharacterized ACR, COG1678
LT988_11005	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LT988_11015	COG0540	Belongs to the ATCase OTCase family
LT988_11030	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LT988_11030	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LT988_11035	COG1519	Transferase
LT988_11050	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LT988_11070	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LT988_11075	COG0513	Belongs to the DEAD box helicase family
LT988_11085	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LT988_11090	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LT988_11105	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LT988_11105	COG2111	Na H antiporter
LT988_11110	COG1006	Multisubunit Na H antiporter MnhC subunit
LT988_11115	COG0651	ATP synthesis coupled electron transport
LT988_11120	COG1863	multisubunit Na H antiporter MnhE subunit
LT988_11125	COG2212	antiporter activity
LT988_11130	COG1320	monovalent cation:proton antiporter activity
LT988_11165	COG0411	ABC transporter
LT988_11195	COG0583	DNA-binding transcription factor activity
LT988_11205	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LT988_11215	COG0140	phosphoribosyl-ATP diphosphatase activity
LT988_11220	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LT988_11225	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LT988_11230	COG0131	Imidazoleglycerol-phosphate dehydratase
LT988_11235	COG0167	dihydroorotate dehydrogenase activity
LT988_11250	COG0463	Glycosyl transferase, family 2
LT988_11260	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LT988_11265	COG0154	amidase activity
LT988_11270	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LT988_11280	COG0582	viral genome integration into host DNA
LT988_11365	COG1175	transmembrane transport
LT988_11370	COG0395	ABC-type sugar transport system, permease component
LT988_11375	COG3842	ATPase activity
LT988_11380	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
LT988_11400	COG0569	domain protein
LT988_11400	COG0189	ligase activity
LT988_11415	COG2321	neutral zinc metallopeptidase
LT988_11430	COG0165	Argininosuccinate lyase
LT988_11445	COG0367	asparagine synthase
LT988_11450	COG0438	transferase activity, transferring glycosyl groups
LT988_11460	COG5001	Diguanylate cyclase
LT988_11465	COG0438	transferase activity, transferring glycosyl groups
LT988_11480	COG0438	transferase activity, transferring glycosyl groups
LT988_11490	COG2914	Belongs to the UPF0125 (RnfH) family
LT988_11505	COG4658	electron transport chain
LT988_11510	COG4656	Part of a membrane complex involved in electron transport
LT988_11515	COG2878	Part of a membrane complex involved in electron transport
LT988_11520	COG4657	Part of a membrane complex involved in electron transport
LT988_11565	COG1201	RNA secondary structure unwinding
LT988_11575	COG5001	Diguanylate cyclase
LT988_11580	COG4175	Glycine betaine
LT988_11580	COG0517	IMP dehydrogenase activity
LT988_11590	COG2113	Glycine betaine
LT988_11600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LT988_11635	COG1652	LysM domain
LT988_11710	COG2442	InterPro IPR007367
LT988_11765	COG2197	response regulator
LT988_11770	COG0668	transmembrane transport
LT988_11775	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LT988_11835	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
LT988_11840	COG2813	Specifically methylates the guanine in position
LT988_11865	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LT988_11905	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
LT988_11910	COG0004	ammonium transporteR
LT988_11915	COG0004	ammonium transporteR
LT988_11935	COG0606	chelatase, subunit chli
LT988_11940	COG0488	(ABC) transporter
LT988_11945	COG0058	SHG alpha-glucan phosphorylase activity
LT988_11960	COG1366	Belongs to the anti-sigma-factor antagonist family
LT988_11965	COG1596	polysaccharide export
LT988_12035	COG0438	transferase activity, transferring glycosyl groups
LT988_12040	COG0438	transferase activity, transferring glycosyl groups
LT988_12060	COG1045	serine acetyltransferase
LT988_12065	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
LT988_12070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LT988_12125	COG0633	Ferredoxin
LT988_12130	COG0426	domain, Protein
LT988_12155	COG1999	signal sequence binding
LT988_12160	COG2847	Copper chaperone PCu(A)C
LT988_12185	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LT988_12190	COG0561	phosphatase activity
LT988_12195	COG1217	gtp-binding protein TYPA
LT988_12200	COG0596	Alpha beta hydrolase
LT988_12225	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LT988_12270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LT988_12285	COG0471	metal ion transport
LT988_12290	COG2177	Part of the ABC transporter FtsEX involved in
LT988_12295	COG2884	Cell division ATP-binding protein ftsE
LT988_12300	COG0552	protein localization to endoplasmic reticulum
LT988_12305	COG0612	Peptidase, M16
LT988_12310	COG0612	Peptidase, M16
LT988_12315	COG0742	ribosomal rna small subunit methyltransferase
LT988_12320	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LT988_12325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LT988_12330	COG0405	Gamma-glutamyltransferase
LT988_12345	COG1215	transferase activity, transferring glycosyl groups
LT988_12350	COG1253	flavin adenine dinucleotide binding
LT988_12355	COG1253	flavin adenine dinucleotide binding
LT988_12375	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
LT988_12380	COG0830	nickel cation binding
LT988_12385	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LT988_12390	COG0314	molybdopterin synthase activity
LT988_12410	COG1671	Belongs to the UPF0178 family
LT988_12415	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LT988_12420	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LT988_12430	COG2022	thiamine diphosphate biosynthetic process
LT988_12435	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LT988_12440	COG3842	ATPase activity
LT988_12445	COG0390	transport system, permease component
LT988_12485	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LT988_12505	COG1166	arginine decarboxylase activity
LT988_12510	COG0375	protein maturation
LT988_12530	COG1215	transferase activity, transferring glycosyl groups
LT988_12625	COG3258	Cytochrome c
LT988_12630	COG2010	Cytochrome c
LT988_12635	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LT988_12640	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LT988_12645	COG1047	Peptidyl-prolyl cis-trans
LT988_12650	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LT988_12655	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LT988_12665	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LT988_12670	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LT988_12675	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LT988_12685	COG0356	it plays a direct role in the translocation of protons across the membrane
LT988_12690	COG3312	ion transport
LT988_12695	COG1475	DNA binding
LT988_12700	COG1192	Involved in chromosome partitioning
LT988_12705	COG0357	Ribosomal RNA small subunit methyltransferase G
LT988_12710	COG0445	tRNA wobble uridine modification
LT988_12715	COG0714	Associated with various cellular activities
LT988_12730	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LT988_12735	COG0706	membrane insertase activity
LT988_12745	COG0594	ribonuclease P activity
LT988_12750	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LT988_12755	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LT988_12760	COG0592	DNA-directed DNA polymerase activity
LT988_12765	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LT988_12770	COG0187	DNA topoisomerase II activity
LT988_12785	COG0751	glycine-tRNA ligase activity
LT988_12790	COG0752	glycyl-tRNA synthetase alpha subunit
LT988_12795	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LT988_12800	COG0174	glutamine synthetase
LT988_12810	COG3852	Histidine kinase
LT988_12815	COG2204	response regulator
LT988_12830	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LT988_12835	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LT988_12840	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LT988_12845	COG1054	Belongs to the UPF0176 family
LT988_12850	COG0640	Transcriptional regulator
LT988_12855	COG4942	peptidase
LT988_12860	COG0793	Belongs to the peptidase S41A family
LT988_12865	COG0693	protein deglycase activity
LT988_12870	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LT988_12880	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LT988_12885	COG1459	type II secretion system
LT988_12895	COG4970	Tfp pilus assembly protein FimT
LT988_12900	COG2165	general secretion pathway protein
LT988_12910	COG3156	type II secretion system protein K
LT988_12930	COG1450	Type ii and iii secretion system protein
LT988_12960	COG0067	glutamate synthase
LT988_12960	COG0069	glutamate synthase activity
LT988_12960	COG0070	glutamate synthase
LT988_12965	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LT988_12970	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LT988_13005	COG0372	Belongs to the citrate synthase family
LT988_13010	COG0039	L-malate dehydrogenase activity
LT988_13015	COG0254	rRNA binding
LT988_13020	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LT988_13025	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LT988_13030	COG0539	negative regulation of cytoplasmic translation
LT988_13035	COG0210	DNA helicase
LT988_13040	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LT988_13045	COG0579	oxidoreductase
LT988_13050	COG1793	dna ligase
LT988_13110	COG4680	protein conserved in bacteria
LT988_13210	COG0386	Belongs to the glutathione peroxidase family
LT988_13235	COG2911	Protein conserved in bacteria
LT988_13245	COG3263	regulation of cellular component size
LT988_13260	COG2003	Belongs to the UPF0758 family
LT988_13265	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LT988_13270	COG0756	dUTP diphosphatase activity
LT988_13280	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LT988_13285	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LT988_13300	COG1872	DUF167
LT988_13320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LT988_13325	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LT988_13335	COG1561	YicC-like family, N-terminal region
LT988_13345	COG3604	Transcriptional regulator
LT988_13350	COG0194	GDP metabolic process
LT988_13360	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LT988_13370	COG0408	coproporphyrinogen oxidase activity
LT988_13385	COG1490	D-aminoacyl-tRNA deacylase activity
LT988_13405	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LT988_13415	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LT988_13420	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LT988_13425	COG0019	diaminopimelate decarboxylase activity
LT988_13450	COG1487	ribonuclease activity
LT988_13480	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LT988_13490	COG3001	Fructosamine kinase
LT988_13500	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LT988_13505	COG1376	ErfK ybiS ycfS ynhG family protein
LT988_13545	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LT988_13555	COG0674	pyruvate-flavodoxin oxidoreductase activity
LT988_13560	COG1013	pyruvate-flavodoxin oxidoreductase activity
LT988_13565	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LT988_13565	COG1042	CoA-binding domain protein
LT988_13565	COG0045	succinate-CoA ligase (ADP-forming) activity
LT988_13570	COG5001	Diguanylate cyclase
LT988_13570	COG2203	Gaf domain
LT988_13570	COG3706	GGDEF domain
LT988_13570	COG4251	negative regulation of phosphorylation
LT988_13600	COG0247	lactate metabolic process
LT988_13620	COG4772	TonB-dependent receptor
LT988_13640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LT988_13645	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
LT988_13660	COG0786	glutamate:sodium symporter activity
LT988_13670	COG0471	metal ion transport
LT988_13670	COG0490	domain, Protein
LT988_13700	COG1263	PTS System
LT988_13700	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LT988_13705	COG4636	protein conserved in cyanobacteria
LT988_13715	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LT988_13730	COG1011	Hydrolase
LT988_13735	COG0494	nUDIX hydrolase
LT988_13745	COG0857	belongs to the CobB CobQ family
LT988_13745	COG0280	phosphate acetyltransferase
LT988_13750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LT988_13755	COG3047	cAMP biosynthetic process
LT988_13755	COG2885	chlorophyll binding
LT988_13760	COG0829	nickel cation binding
LT988_13765	COG0831	urea catabolic process
LT988_13770	COG0832	Belongs to the urease beta subunit family
LT988_13775	COG0804	urea catabolic process
LT988_13780	COG0018	arginyl-trna synthetase
LT988_13790	COG0704	Plays a role in the regulation of phosphate uptake
LT988_13795	COG0588	phosphoglycerate mutase activity
LT988_13810	COG3920	Histidine kinase
LT988_13820	COG0651	ATP synthesis coupled electron transport
LT988_13825	COG0651	ATP synthesis coupled electron transport
LT988_13845	COG1320	monovalent cation:proton antiporter activity
LT988_13875	COG0443	Heat shock 70 kDa protein
LT988_13885	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LT988_13890	COG1652	LysM domain
LT988_13935	COG4636	protein conserved in cyanobacteria
LT988_13940	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LT988_13945	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LT988_13950	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LT988_13955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LT988_13970	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LT988_13975	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LT988_13980	COG1127	ABC transporter
LT988_13995	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LT988_14010	COG1137	ATPase activity
LT988_14030	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LT988_14035	COG1660	Displays ATPase and GTPase activities
LT988_14045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LT988_14050	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LT988_14055	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LT988_14065	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LT988_14075	COG0315	cyclic pyranopterin monophosphate synthase activity
LT988_14080	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LT988_14085	COG0205	6-phosphofructokinase activity
LT988_14090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LT988_14095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LT988_14100	COG0006	proline dipeptidase activity
LT988_14125	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LT988_14130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LT988_14135	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LT988_14155	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LT988_14160	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LT988_14175	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
LT988_14180	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LT988_14190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LT988_14195	COG0134	indole-3-glycerol-phosphate synthase activity
LT988_14200	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LT988_14220	COG0546	phosphoglycolate phosphatase activity
LT988_14225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LT988_14230	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LT988_14260	COG2205	protein histidine kinase activity
LT988_14265	COG0745	RESPONSE REGULATOR receiver
LT988_14275	COG0667	Aldo Keto reductase
LT988_14290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LT988_14295	COG0405	Gamma-glutamyltransferase
LT988_14305	COG3577	Aspartyl protease
LT988_14325	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LT988_14330	COG0668	transmembrane transport
LT988_14335	COG3038	cytochrome b561
LT988_14340	COG0446	pyridine nucleotide-disulphide oxidoreductase
LT988_14390	COG1842	Phage shock protein A
LT988_14400	COG5002	protein histidine kinase activity
LT988_14410	COG1404	Belongs to the peptidase S8 family
LT988_14420	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LT988_14520	COG0438	transferase activity, transferring glycosyl groups
LT988_14530	COG1216	Glycosyl transferase, family 2
LT988_14550	COG1132	(ABC) transporter
LT988_14600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LT988_14630	COG0604	alcohol dehydrogenase
LT988_14630	COG3321	synthase
LT988_14645	COG0673	inositol 2-dehydrogenase activity
LT988_14680	COG3321	synthase
LT988_14680	COG0604	alcohol dehydrogenase
LT988_14695	COG2091	lysine biosynthetic process via aminoadipic acid
LT988_14715	COG1216	Glycosyl transferase, family 2
LT988_14715	COG0463	Glycosyl transferase, family 2
LT988_14735	COG1216	Glycosyl transferase, family 2
LT988_14770	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LT988_14780	COG2226	methyltransferase
LT988_14790	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LT988_14795	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LT988_14800	COG0438	transferase activity, transferring glycosyl groups
LT988_14845	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LT988_14850	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LT988_14855	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
LT988_14860	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LT988_14865	COG0509	glycine decarboxylation via glycine cleavage system
LT988_14870	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LT988_14885	COG0495	leucyl-tRNA aminoacylation
LT988_14900	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LT988_14905	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LT988_14930	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LT988_14935	COG2967	ApaG domain
LT988_14955	COG4974	Belongs to the 'phage' integrase family
LT988_14960	COG0582	viral genome integration into host DNA
LT988_14965	COG0582	viral genome integration into host DNA
LT988_14985	COG3081	Nucleoid-associated protein
LT988_15020	COG0582	viral genome integration into host DNA
LT988_15025	COG0582	viral genome integration into host DNA
LT988_15030	COG4974	Belongs to the 'phage' integrase family
LT988_15100	COG2823	Periplasmic or secreted lipoprotein
LT988_15110	COG3237	CsbD-like
LT988_15115	COG5001	Diguanylate cyclase
LT988_15130	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LT988_15135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LT988_15140	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LT988_15145	COG3178	'Phosphotransferase
LT988_15150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LT988_15155	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LT988_15160	COG0723	plastoquinol--plastocyanin reductase activity
LT988_15165	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LT988_15170	COG2857	Cytochrome c1
LT988_15175	COG0625	glutathione transferase activity
LT988_15180	COG2969	positive regulation of protein catabolic process
LT988_15200	COG0628	permease
LT988_15240	COG2852	Protein conserved in bacteria
LT988_15260	COG1802	Transcriptional regulator
LT988_15270	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LT988_15275	COG0352	thiamine-phosphate diphosphorylase activity
LT988_15280	COG0352	thiamine-phosphate diphosphorylase activity
LT988_15280	COG0351	phosphomethylpyrimidine kinase
LT988_15285	COG1773	rubredoxin
LT988_15300	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LT988_15310	COG0316	Belongs to the HesB IscA family
LT988_15320	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LT988_15355	COG0768	penicillin binding
LT988_15365	COG1575	Belongs to the MenA family. Type 1 subfamily
LT988_15375	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LT988_15380	COG1169	isochorismate synthase
LT988_15390	COG0702	epimerase
LT988_15405	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LT988_15410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LT988_15415	COG0842	Transport permease protein
LT988_15415	COG1129	ABC transporter
LT988_15420	COG0842	Transport permease protein
LT988_15425	COG0488	(ABC) transporter
LT988_15460	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
LT988_15465	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LT988_15475	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
LT988_15485	COG1233	COG1233 Phytoene dehydrogenase and related
LT988_15490	COG1562	ergosterol biosynthetic process
LT988_15500	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LT988_15510	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LT988_15535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LT988_15555	COG1477	protein flavinylation
LT988_15570	COG2255	four-way junction helicase activity
LT988_15575	COG0277	FAD linked oxidase domain protein
LT988_15610	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LT988_15620	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LT988_15630	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LT988_15660	COG0584	glycerophosphoryl diester phosphodiesterase
LT988_15705	COG2358	TRAP transporter, solute receptor (TAXI family
LT988_15715	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LT988_15730	COG0433	COG0433 Predicted ATPase
LT988_15740	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LT988_15745	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LT988_15820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LT988_15845	COG0366	Alpha amylase catalytic
LT988_15850	COG0297	glycogen (starch) synthase activity
LT988_15855	COG2723	6-phospho-beta-galactosidase activity
LT988_15860	COG4178	(ABC) transporter
LT988_15870	COG3459	Glycosyltransferase 36 associated
LT988_15875	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
LT988_15885	COG2943	transferase activity, transferring hexosyl groups
LT988_15885	COG3416	Protein conserved in bacteria
LT988_15900	COG0443	Heat shock 70 kDa protein
LT988_15940	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LT988_15950	COG0343	queuine tRNA-ribosyltransferase activity
LT988_15955	COG1862	Preprotein translocase
LT988_15960	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LT988_15965	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LT988_15990	COG4181	ATPase activity
LT988_15995	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LT988_16000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LT988_16030	COG4783	chaperone-mediated protein folding
LT988_16045	COG1560	Kdo2-lipid A biosynthetic process
LT988_16090	COG1408	metallophosphoesterase
LT988_16095	COG2723	6-phospho-beta-galactosidase activity
LT988_16100	COG1216	Glycosyl transferase, family 2
LT988_16110	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
LT988_16115	COG5001	Diguanylate cyclase
LT988_16130	COG4251	negative regulation of phosphorylation
LT988_16135	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
LT988_16155	COG0745	RESPONSE REGULATOR receiver
LT988_16165	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LT988_16175	COG0840	transmembrane signaling receptor activity
LT988_16185	COG2920	part of a sulfur-relay system
LT988_16190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LT988_16195	COG0071	Belongs to the small heat shock protein (HSP20) family
LT988_16200	COG3012	SEC-C Motif Domain Protein
LT988_16210	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LT988_16220	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
LT988_16225	COG3259	Nickel-dependent hydrogenase
LT988_16235	COG1674	ftsk spoiiie
LT988_16240	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LT988_16245	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LT988_16260	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LT988_16265	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LT988_16270	COG1652	LysM domain
LT988_16275	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
LT988_16290	COG1160	GTP binding
LT988_16295	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LT988_16300	COG2976	Protein conserved in bacteria
LT988_16305	COG0124	histidyl-tRNA synthetase
LT988_16320	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LT988_16325	COG0105	UTP biosynthetic process
LT988_16345	COG0737	Belongs to the 5'-nucleotidase family
LT988_16360	COG0848	biopolymer transport protein
LT988_16390	COG0280	phosphate acetyltransferase
LT988_16390	COG0281	malic enzyme
LT988_16405	COG1999	signal sequence binding
LT988_16420	COG0583	DNA-binding transcription factor activity
LT988_16455	COG3002	Belongs to the UPF0753 family
LT988_16460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LT988_16460	COG2111	Na H antiporter
LT988_16495	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LT988_16500	COG0424	maF-like protein
LT988_16520	COG0312	modulator of DNA gyrase
LT988_16525	COG0312	modulator of DNA gyrase
LT988_16545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LT988_16550	COG0560	Phosphoserine phosphatase
LT988_16550	COG3830	Belongs to the UPF0237 family
LT988_16560	COG2211	Major facilitator Superfamily
LT988_16570	COG0142	geranyltranstransferase activity
LT988_16575	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LT988_16585	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LT988_16625	COG0237	dephospho-CoA kinase activity
LT988_16650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LT988_16660	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
LT988_16665	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LT988_16715	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LT988_16725	COG2133	pyrroloquinoline quinone binding
LT988_16730	COG0137	argininosuccinate synthase activity
LT988_16755	COG0463	Glycosyl transferase, family 2
LT988_16770	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LT988_16795	COG0583	DNA-binding transcription factor activity
LT988_16805	COG0546	phosphoglycolate phosphatase activity
LT988_16810	COG0714	Associated with various cellular activities
LT988_16830	COG2304	oxidoreductase activity
LT988_16845	COG0583	DNA-binding transcription factor activity
LT988_16885	COG1534	Rna-binding protein
LT988_16890	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LT988_16895	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LT988_16905	COG0776	regulation of translation
LT988_16910	COG0156	8-amino-7-oxononanoate synthase activity
LT988_16915	COG4999	Histidine kinase
LT988_16915	COG3850	Histidine kinase
LT988_16915	COG2205	protein histidine kinase activity
LT988_16915	COG3437	response regulator, receiver
LT988_16920	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LT988_16950	COG0488	(ABC) transporter
LT988_16955	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LT988_16980	COG3045	CreA protein
LT988_17010	COG0651	ATP synthesis coupled electron transport
LT988_17015	COG0650	Formate hydrogenlyase subunit 4
LT988_17025	COG0651	ATP synthesis coupled electron transport
LT988_17030	COG0649	NAD binding
LT988_17035	COG3260	NADH ubiquinone oxidoreductase 20
LT988_17040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LT988_17065	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LT988_17070	COG0795	lipopolysaccharide-transporting ATPase activity
LT988_17080	COG4191	Histidine kinase
LT988_17085	COG4566	intracellular signal transduction
LT988_17090	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LT988_17105	COG2885	chlorophyll binding
LT988_17120	COG2915	High frequency lysogenization protein hflD homolog
LT988_17125	COG0482	sulfurtransferase activity
LT988_17135	COG1278	Cold shock
LT988_17140	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LT988_17145	COG0542	response to heat
LT988_17150	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LT988_17155	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LT988_17160	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LT988_17170	COG0492	ferredoxin-NADP+ reductase activity
LT988_17180	COG0791	NLP P60 protein
LT988_17195	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LT988_17205	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LT988_17210	COG0733	neurotransmitter:sodium symporter activity
LT988_17215	COG2867	negative regulation of translational initiation
LT988_17220	COG2914	Belongs to the UPF0125 (RnfH) family
LT988_17230	COG0735	belongs to the Fur family
LT988_17235	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LT988_17255	COG3710	Transcriptional regulator
LT988_17325	COG1484	DNA-dependent DNA replication
LT988_17380	COG4372	Transposase
LT988_17395	COG2124	cytochrome p450
LT988_17400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LT988_17425	COG4453	Protein conserved in bacteria
LT988_17520	COG1201	RNA secondary structure unwinding
LT988_17530	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LT988_17635	COG3344	reverse transcriptase
LT988_17695	COG4974	Belongs to the 'phage' integrase family
LT988_17715	COG0501	Belongs to the peptidase M48B family
LT988_17720	COG3038	cytochrome b561
LT988_17750	COG0386	Belongs to the glutathione peroxidase family
LT988_17760	COG1793	dna ligase
LT988_17765	COG3046	protein related to deoxyribodipyrimidine photolyase
LT988_17795	COG0463	Glycosyl transferase, family 2
LT988_17810	COG0501	Belongs to the peptidase M48B family
LT988_17815	COG1704	LemA family
LT988_17820	COG0811	peptide transport
LT988_17830	COG1132	(ABC) transporter
LT988_17835	COG1663	tetraacyldisaccharide 4'-kinase activity
LT988_17840	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LT988_17860	COG4890	Cyd operon protein YbgT
LT988_17865	COG1294	oxidase, subunit
LT988_17885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LT988_17890	COG0488	(ABC) transporter
LT988_17900	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LT988_17910	COG0243	molybdopterin cofactor binding
LT988_17915	COG0437	4 iron, 4 sulfur cluster binding
LT988_17920	COG3302	dmso reductase anchor subunit
LT988_17925	COG0598	Magnesium transport protein CorA
LT988_17940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LT988_17975	COG2204	response regulator
LT988_17990	COG4251	negative regulation of phosphorylation
LT988_18005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LT988_18010	COG3065	identical protein binding
LT988_18020	COG2835	tetraacyldisaccharide 4'-kinase activity
LT988_18060	COG0674	pyruvate-flavodoxin oxidoreductase activity
LT988_18060	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LT988_18065	COG1013	pyruvate-flavodoxin oxidoreductase activity
LT988_18085	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LT988_18095	COG4636	protein conserved in cyanobacteria
LT988_18160	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LT988_18185	COG3409	Peptidoglycan-binding domain 1 protein
LT988_18185	COG3267	Type II secretory pathway component ExeA
LT988_18195	COG2239	Acts as a magnesium transporter
LT988_18220	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LT988_18250	COG0640	Transcriptional regulator
LT988_18255	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LT988_18270	COG1752	Esterase of the alpha-beta hydrolase superfamily
LT988_18275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LT988_18300	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LT988_18315	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LT988_18325	COG2307	Protein conserved in bacteria
LT988_18325	COG2308	Evidence 4 Homologs of previously reported genes of
LT988_18335	COG0318	PFAM AMP-dependent synthetase and ligase
LT988_18350	COG1067	ATP-dependent peptidase activity
LT988_18360	COG1355	regulation of microtubule-based process
LT988_18435	COG3344	reverse transcriptase
LT988_18465	COG3119	arylsulfatase activity
LT988_18475	COG3119	arylsulfatase activity
LT988_18485	COG0076	glutamate decarboxylase activity
LT988_18500	COG0525	valine-tRNA ligase activity
LT988_18510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LT988_18560	COG3086	response to oxidative stress
LT988_18575	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
LT988_18605	COG4988	ABC transporter
LT988_18610	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LT988_18615	COG4636	protein conserved in cyanobacteria
LT988_18705	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LT988_18715	COG0693	protein deglycase activity
LT988_18720	COG2105	PFAM AIG2 family protein
LT988_18750	COG1116	anion transmembrane transporter activity
LT988_18760	COG3665	Urea carboxylase-associated protein
LT988_18775	COG0574	Belongs to the PEP-utilizing enzyme family
LT988_18775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LT988_18805	COG0189	ligase activity
LT988_18810	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LT988_18815	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LT988_18820	COG0196	riboflavin kinase activity
LT988_18825	COG0728	peptidoglycan biosynthetic process
LT988_18830	COG0268	Binds directly to 16S ribosomal RNA
LT988_18835	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LT988_18860	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LT988_18865	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LT988_18880	COG3278	Belongs to the heme-copper respiratory oxidase family
LT988_18920	COG2217	Heavy metal translocating P-type atpase
LT988_18935	COG0033	Phosphoglucomutase
LT988_18940	COG0326	Molecular chaperone. Has ATPase activity
LT988_18945	COG0563	adenylate kinase activity
LT988_18950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LT988_18960	COG1959	2 iron, 2 sulfur cluster binding
LT988_18965	COG2890	protein-(glutamine-N5) methyltransferase activity
LT988_18975	COG0318	PFAM AMP-dependent synthetase and ligase
LT988_18980	COG0544	peptidyl-prolyl cis-trans isomerase activity
LT988_18985	COG0740	serine-type endopeptidase activity
LT988_18990	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LT988_18995	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LT988_19015	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LT988_19030	COG0601	transmembrane transport
LT988_19035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LT988_19050	COG1278	Cold shock
LT988_19055	COG0746	molybdenum cofactor guanylyltransferase activity
LT988_19065	COG3034	peptidoglycan biosynthetic process
LT988_19075	COG0741	lytic transglycosylase activity
LT988_19075	COG1388	LysM domain
LT988_19085	COG0328	RNA-DNA hybrid ribonuclease activity
LT988_19090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LT988_19095	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LT988_19105	COG0504	CTP synthase activity
LT988_19110	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LT988_19115	COG0148	phosphopyruvate hydratase activity
LT988_19120	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LT988_19125	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LT988_19130	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LT988_19135	COG0585	pseudouridine synthase activity
LT988_19140	COG3174	membrane
LT988_19180	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LT988_19190	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LT988_19210	COG0567	Dehydrogenase, E1 component
LT988_19235	COG2205	protein histidine kinase activity
LT988_19235	COG0784	Response regulator, receiver
LT988_19235	COG5002	protein histidine kinase activity
LT988_19250	COG4771	TonB-dependent receptor
LT988_19260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LT988_19260	COG0543	2 iron, 2 sulfur cluster binding
LT988_19280	COG0724	RNA recognition motif
LT988_19285	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LT988_19290	COG0339	signal peptide processing
LT988_19300	COG1196	nuclear chromosome segregation
LT988_19305	COG3115	cell septum assembly
LT988_19310	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LT988_19335	COG3005	denitrification pathway
LT988_19345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LT988_19350	COG2350	Protein conserved in bacteria
LT988_19355	COG2917	probably involved in intracellular septation
LT988_19360	COG1115	amino acid carrier protein
LT988_19365	COG0271	Belongs to the BolA IbaG family
LT988_19375	COG0569	domain protein
LT988_19380	COG2204	response regulator
LT988_19385	COG5000	phosphorelay sensor kinase activity
LT988_19400	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LT988_19405	COG0242	peptide deformylase activity
LT988_19415	COG0758	DNA mediated transformation
LT988_19420	COG2922	Belongs to the Smg family
LT988_19430	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LT988_19435	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LT988_19445	COG0701	Predicted permease
LT988_19460	COG3850	Histidine kinase
LT988_19465	COG2197	response regulator
LT988_19470	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LT988_19485	COG2951	lytic endotransglycosylase activity
LT988_19490	COG0432	Pfam Uncharacterised protein family UPF0047
LT988_19495	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LT988_19520	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LT988_19525	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LT988_19545	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LT988_19700	COG0438	transferase activity, transferring glycosyl groups
LT988_19705	COG0110	maltose O-acetyltransferase activity
LT988_19710	COG0297	glycogen (starch) synthase activity
LT988_19725	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LT988_19750	COG3267	Type II secretory pathway component ExeA
LT988_19750	COG3409	Peptidoglycan-binding domain 1 protein
LT988_19780	COG2337	Toxic component of a toxin-antitoxin (TA) module
LT988_19805	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LT988_19810	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LT988_19815	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LT988_19880	COG4464	protein tyrosine phosphatase activity
LT988_19895	COG0484	heat shock protein binding
LT988_19925	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
LT988_19930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LT988_19930	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LT988_19935	COG0516	GMP reductase activity
LT988_19935	COG0517	IMP dehydrogenase activity
LT988_19970	COG5265	(ABC) transporter
LT988_19975	COG3850	Histidine kinase
LT988_19980	COG2197	response regulator
LT988_19985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LT988_20005	COG0215	cysteine-tRNA ligase activity
LT988_20045	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LT988_20050	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LT988_20055	COG0537	adenosine 5'-monophosphoramidase activity
LT988_20060	COG0850	regulation of cytokinetic process
LT988_20065	COG2894	cell division
LT988_20070	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LT988_20080	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LT988_20085	COG1331	Highly conserved protein containing a thioredoxin domain
LT988_20090	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LT988_20100	COG0824	Thioesterase
LT988_20120	COG0823	Involved in the tonB-independent uptake of proteins
LT988_20125	COG2885	chlorophyll binding
LT988_20130	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LT988_20150	COG1940	carbohydrate kinase activity
LT988_20155	COG0702	epimerase
LT988_20175	COG1028	Short-chain dehydrogenase reductase Sdr
LT988_20180	COG0647	UMP catabolic process
LT988_20205	COG1674	ftsk spoiiie
LT988_20235	COG4115	mRNA cleavage
LT988_20260	COG2239	Acts as a magnesium transporter
LT988_20265	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LT988_20265	COG0515	serine threonine protein kinase
LT988_20270	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LT988_20280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LT988_20310	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LT988_20315	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LT988_20325	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LT988_20335	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LT988_20340	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LT988_20345	COG0193	aminoacyl-tRNA hydrolase activity
LT988_20395	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LT988_20400	COG0081	regulation of translation
LT988_20405	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LT988_20410	COG0222	ribosome binding
LT988_20415	COG0085	RNA polymerase activity
LT988_20420	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LT988_20425	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LT988_20430	COG0049	tRNA binding
LT988_20435	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LT988_20445	COG0051	transcription antitermination factor activity, RNA binding
LT988_20450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LT988_20455	COG0088	Forms part of the polypeptide exit tunnel
LT988_20460	COG0089	rRNA binding
LT988_20465	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LT988_20470	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LT988_20475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LT988_20480	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LT988_20485	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LT988_20490	COG0255	Belongs to the universal ribosomal protein uL29 family
LT988_20495	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LT988_20500	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LT988_20505	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LT988_20510	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LT988_20515	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LT988_20520	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LT988_20525	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LT988_20535	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LT988_20540	COG1841	ribosomal large subunit assembly
LT988_20545	COG0200	Binds to the 23S rRNA
LT988_20550	COG0201	protein transport
LT988_20555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LT988_20560	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LT988_20565	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LT988_20570	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LT988_20575	COG0202	RNA polymerase activity
LT988_20580	COG0203	ribosomal protein L17
LT988_20595	COG0513	Belongs to the DEAD box helicase family
LT988_20605	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LT988_20610	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LT988_20615	COG0077	Prephenate dehydratase
LT988_20615	COG1605	Chorismate mutase
LT988_20620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LT988_20630	COG5001	Diguanylate cyclase
LT988_20630	COG3300	MHYT domain
LT988_20635	COG1070	Carbohydrate kinase
LT988_20640	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LT988_20655	COG2197	response regulator
LT988_20720	COG1566	PFAM secretion protein HlyD family protein
LT988_20790	COG0406	alpha-ribazole phosphatase activity
LT988_20800	COG0668	transmembrane transport
LT988_20815	COG2985	domain, Protein
LT988_20825	COG0076	glutamate decarboxylase activity
LT988_20830	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LT988_20835	COG2326	polyphosphate kinase activity
LT988_20865	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LT988_20870	COG1127	ABC transporter
LT988_20905	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LT988_20910	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
LT988_20960	COG3119	arylsulfatase activity
LT988_20970	COG3064	Membrane
LT988_20980	COG0475	glutathione-regulated potassium exporter activity
LT988_20995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LT988_21000	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LT988_21005	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LT988_21010	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LT988_21015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LT988_21020	COG0587	DNA-directed DNA polymerase activity
LT988_21025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LT988_21135	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LT988_21165	COG1151	hydroxylamine reductase activity
LT988_21175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LT988_21175	COG4797	methyltransferase
LT988_21180	COG4953	penicillin-binding protein 1C
LT988_21200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LT988_21225	COG1131	(ABC) transporter
LT988_21230	COG0842	Transport permease protein
LT988_21235	COG0842	Transport permease protein
LT988_21250	COG1492	cobalamin metabolic process
LT988_21260	COG5522	Integral membrane protein (intg_mem_TP0381)
LT988_21300	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LT988_21300	COG0116	Belongs to the methyltransferase superfamily
LT988_21305	COG1643	Atp-dependent helicase
LT988_21325	COG1073	alpha beta
LT988_21330	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LT988_21345	COG3609	addiction module antidote protein, CC2985 family
LT988_21350	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LT988_21355	COG0066	3-isopropylmalate dehydratase activity
LT988_21360	COG0473	3-isopropylmalate dehydrogenase activity
LT988_21375	COG0101	tRNA pseudouridine synthase activity
LT988_21380	COG0135	phosphoribosylanthranilate isomerase activity
LT988_21385	COG0133	tryptophan synthase activity
LT988_21390	COG0159	tryptophan synthase activity
LT988_21395	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LT988_21400	COG0285	dihydrofolate synthase activity
LT988_21410	COG1286	toxin biosynthetic process
LT988_21435	COG1943	Transposase
LT988_21470	COG1487	ribonuclease activity
LT988_21475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LT988_21490	COG1487	ribonuclease activity
LT988_21535	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LT988_21550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LT988_21555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LT988_21565	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LT988_21575	COG1979	alcohol dehydrogenase
LT988_21580	COG0481	GTPase activity
LT988_21585	COG0681	Belongs to the peptidase S26 family
LT988_21595	COG0571	ribonuclease III activity
LT988_21605	COG1381	Involved in DNA repair and RecF pathway recombination
LT988_21610	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LT988_21615	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LT988_21625	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
LT988_21635	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LT988_21640	COG1993	acr, cog1993
LT988_21645	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LT988_21650	COG3264	Mechanosensitive ion channel
LT988_21650	COG1511	domain protein
LT988_21705	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LT988_21715	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LT988_21735	COG0659	secondary active sulfate transmembrane transporter activity
LT988_21810	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LT988_21815	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LT988_21885	COG0577	efflux transmembrane transporter activity
LT988_21885	COG1136	(ABC) transporter
LT988_21920	COG0557	exoribonuclease II activity
LT988_21925	COG3108	Peptidase M15
LT988_21940	COG2046	Belongs to the sulfate adenylyltransferase family
LT988_21965	COG4467	Involved in initiation control of chromosome replication
LT988_22000	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
LT988_22045	COG2944	sequence-specific DNA binding
LT988_22085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LT988_22090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LT988_22110	COG0529	Catalyzes the synthesis of activated sulfate
LT988_22125	COG3842	ATPase activity
LT988_22130	COG1178	ABC-type Fe3 transport system permease component
LT988_22135	COG1840	ABC-type Fe3 transport system, periplasmic component
LT988_22140	COG0719	Fe-S assembly protein
LT988_22145	COG0396	ATPase activity
LT988_22150	COG0719	Fe-S assembly protein
LT988_22155	COG2151	metal-sulfur cluster biosynthetic enzyme
LT988_22165	COG1968	undecaprenyl-diphosphatase activity
LT988_22180	COG2183	response to ionizing radiation
LT988_22230	COG1863	multisubunit Na H antiporter MnhE subunit
LT988_22235	COG2212	antiporter activity
LT988_22240	COG1320	monovalent cation:proton antiporter activity
LT988_22250	COG2111	Na H antiporter
LT988_22250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LT988_22255	COG1006	Multisubunit Na H antiporter MnhC subunit
LT988_22260	COG0651	ATP synthesis coupled electron transport
LT988_22265	COG1007	ATP synthesis coupled electron transport
LT988_22270	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LT988_22275	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LT988_22280	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LT988_22285	COG0649	NAD binding
LT988_22290	COG0493	'glutamate synthase
LT988_22305	COG0577	efflux transmembrane transporter activity
LT988_22355	COG1546	Belongs to the CinA family
LT988_22370	COG2137	regulation of response to DNA damage stimulus
LT988_22375	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LT988_22385	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LT988_22400	COG0590	tRNA wobble adenosine to inosine editing
LT988_22420	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LT988_22450	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LT988_22470	COG2943	transferase activity, transferring hexosyl groups
LT988_22490	COG0438	transferase activity, transferring glycosyl groups
LT988_22505	COG0420	3'-5' exonuclease activity
LT988_22525	COG0604	alcohol dehydrogenase
LT988_22540	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LT988_22545	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LT988_22550	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LT988_22560	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LT988_22565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LT988_22565	COG0072	phenylalanine-tRNA ligase activity
LT988_22570	COG0776	regulation of translation
LT988_22625	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LT988_22630	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LT988_22635	COG3409	Peptidoglycan-binding domain 1 protein
LT988_22635	COG3429	Glucose-6-phosphate dehydrogenase subunit
LT988_22650	COG1073	alpha beta
LT988_22655	COG4302	ethanolamine ammonia-lyase activity
LT988_22660	COG4303	Ethanolamine ammonia lyase large subunit
LT988_22665	COG0531	amino acid
LT988_22680	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LT988_22695	COG1254	Belongs to the acylphosphatase family
LT988_22700	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LT988_22705	COG1592	Rubrerythrin
LT988_22720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LT988_22745	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
LT988_22790	COG0704	Plays a role in the regulation of phosphate uptake
LT988_22810	COG2239	Acts as a magnesium transporter
LT988_22820	COG0737	Belongs to the 5'-nucleotidase family
LT988_22870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LT988_22875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LT988_22880	COG0581	inorganic phosphate transmembrane transporter activity
LT988_22890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LT988_22900	COG1785	Belongs to the alkaline phosphatase family
LT988_22915	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LT988_22920	COG0442	prolyl-tRNA aminoacylation
LT988_22930	COG0028	Belongs to the TPP enzyme family
LT988_22940	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LT988_22945	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LT988_22950	COG0303	'Molybdopterin
LT988_22955	COG0521	Mo-molybdopterin cofactor biosynthetic process
LT988_22965	COG0516	GMP reductase activity
LT988_22965	COG0517	IMP dehydrogenase activity
LT988_22990	COG0322	excinuclease ABC activity
LT988_23015	COG0281	malic enzyme
LT988_23020	COG0114	fumarate hydratase activity
LT988_23035	COG0842	Transport permease protein
LT988_23035	COG1716	ATPase activity
LT988_23035	COG1131	(ABC) transporter
LT988_23060	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LT988_23080	COG1360	Flagellar Motor Protein
LT988_23150	COG3344	reverse transcriptase
LT988_23255	COG1174	glycine betaine transport
LT988_23260	COG1125	glycine betaine transport
LT988_23260	COG0517	IMP dehydrogenase activity
LT988_23275	COG0429	hydrolase of the alpha beta-hydrolase fold
LT988_23280	COG1538	Outer membrane efflux protein
LT988_23285	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LT988_23290	COG2814	Major facilitator Superfamily
LT988_23340	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LT988_23365	COG2860	membrane
LT988_23370	COG0129	dihydroxy-acid dehydratase activity
LT988_23460	COG0436	Aminotransferase
LT988_23490	COG1131	(ABC) transporter
LT988_23500	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LT988_23505	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
LT988_23530	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LT988_23530	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LT988_23560	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LT988_23565	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LT988_23565	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LT988_23570	COG0802	atpase or kinase
LT988_23575	COG0860	N-Acetylmuramoyl-L-alanine amidase
LT988_23585	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LT988_23590	COG1923	regulation of RNA biosynthetic process
LT988_23595	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LT988_23600	COG0330	HflC and HflK could
LT988_23605	COG0330	HflC and HflK could
LT988_23615	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
LT988_23620	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LT988_23630	COG5016	pyruvate
LT988_23630	COG0511	ligase activity, forming carbon-carbon bonds
LT988_23635	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
LT988_23640	COG1399	metal-binding, possibly nucleic acid-binding protein
LT988_23650	COG0416	fatty acid biosynthetic process
LT988_23655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LT988_23670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LT988_23675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LT988_23685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LT988_23690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LT988_23705	COG0084	hydrolase, TatD family'
LT988_23720	COG0330	HflC and HflK could
LT988_23725	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LT988_23755	COG2204	response regulator
LT988_23765	COG0489	protein tyrosine kinase activity
LT988_23825	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LT988_23890	COG1215	transferase activity, transferring glycosyl groups
LT988_23915	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LT988_23925	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LT988_23965	COG3609	addiction module antidote protein, CC2985 family
LT988_23975	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LT988_23980	COG2954	triphosphatase activity
LT988_23995	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LT988_24000	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LT988_24005	COG0308	aminopeptidase N
LT988_24020	COG1177	transmembrane transport
LT988_24025	COG1176	ABC-type spermidine putrescine transport system, permease component I
LT988_24030	COG3842	ATPase activity
LT988_24035	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LT988_24050	COG0107	imidazoleglycerol-phosphate synthase activity
LT988_24060	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
LT988_24060	COG2878	Part of a membrane complex involved in electron transport
LT988_24065	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LT988_24065	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LT988_24065	COG1013	pyruvate-flavodoxin oxidoreductase activity
LT988_24065	COG0674	pyruvate-flavodoxin oxidoreductase activity
LT988_24070	COG4656	Part of a membrane complex involved in electron transport
LT988_24075	COG4658	electron transport chain
LT988_24085	COG4660	Part of a membrane complex involved in electron transport
LT988_24090	COG4657	Part of a membrane complex involved in electron transport
LT988_24135	COG3220	belongs to the UPF0276 family
LT988_24150	COG4944	Protein of unknown function (DUF1109)
LT988_24165	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LT988_24170	COG0456	acetyltransferase
LT988_24175	COG0306	phosphate transporter
LT988_24180	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LT988_24180	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LT988_24180	COG1013	pyruvate-flavodoxin oxidoreductase activity
LT988_24180	COG0674	pyruvate-flavodoxin oxidoreductase activity
LT988_24185	COG0167	dihydroorotate dehydrogenase activity
LT988_24210	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
LT988_24225	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LT988_24230	COG3162	membrane
LT988_24265	COG4974	Belongs to the 'phage' integrase family
LT988_24315	COG0681	Belongs to the peptidase S26 family
LT988_24435	COG2003	Belongs to the UPF0758 family
LT988_24495	COG3591	Belongs to the peptidase S1B family
LT988_24525	COG3591	Belongs to the peptidase S1B family
LT988_24525	COG1864	DNA RNA non-specific endonuclease
LT988_24560	COG1404	Belongs to the peptidase S8 family
LT988_24565	COG1404	Belongs to the peptidase S8 family
LT988_24590	COG1238	metal cluster binding
LT988_24675	COG4453	Protein conserved in bacteria
LT988_24705	COG0668	transmembrane transport
LT988_24710	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
LT988_24755	COG1272	protein, Hemolysin III
LT988_24770	COG3459	Glycosyltransferase 36 associated
LT988_24815	COG3409	Peptidoglycan-binding domain 1 protein
LT988_24815	COG3267	Type II secretory pathway component ExeA
LT988_24830	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LT988_24835	COG2823	Periplasmic or secreted lipoprotein
LT988_24850	COG3344	reverse transcriptase
LT988_24870	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LT988_24910	COG2130	NADP-dependent
LT988_24945	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LT988_24955	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LT988_24965	COG0356	it plays a direct role in the translocation of protons across the membrane
LT988_24985	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LT988_24995	COG0789	Transcriptional regulator
LT988_25045	COG0702	epimerase
LT988_25050	COG1525	nuclease
LT988_25130	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LT988_25160	COG4804	nuclease activity
LT988_25180	COG0166	Belongs to the GPI family