locus-tag	class	description
KFB96_00010	COG0402	S-adenosylhomocysteine deaminase activity
KFB96_00015	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
KFB96_00020	COG1942	4-Oxalocrotonate Tautomerase
KFB96_00025	COG0456	acetyltransferase
KFB96_00030	COG0745	RESPONSE REGULATOR receiver
KFB96_00040	COG2200	EAL domain
KFB96_00055	COG3852	Histidine kinase
KFB96_00120	COG4453	Protein conserved in bacteria
KFB96_00175	COG2995	paraquat-inducible protein a
KFB96_00180	COG3008	intermembrane lipid transfer
KFB96_00200	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KFB96_00205	COG1918	ferrous iron import across plasma membrane
KFB96_00220	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KFB96_00220	COG4797	methyltransferase
KFB96_00225	COG4953	penicillin-binding protein 1C
KFB96_00245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFB96_00270	COG1492	cobalamin metabolic process
KFB96_00275	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KFB96_00280	COG5522	Integral membrane protein (intg_mem_TP0381)
KFB96_00285	COG0116	Belongs to the methyltransferase superfamily
KFB96_00285	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KFB96_00290	COG1643	Atp-dependent helicase
KFB96_00310	COG1073	alpha beta
KFB96_00315	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KFB96_00325	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
KFB96_00330	COG0066	3-isopropylmalate dehydratase activity
KFB96_00335	COG0473	3-isopropylmalate dehydrogenase activity
KFB96_00350	COG0101	tRNA pseudouridine synthase activity
KFB96_00355	COG0135	phosphoribosylanthranilate isomerase activity
KFB96_00360	COG0133	tryptophan synthase activity
KFB96_00365	COG0159	tryptophan synthase activity
KFB96_00370	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
KFB96_00375	COG0285	dihydrofolate synthase activity
KFB96_00385	COG1286	toxin biosynthetic process
KFB96_00415	COG4969	Belongs to the N-Me-Phe pilin family
KFB96_00430	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KFB96_00445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFB96_00450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFB96_00455	COG1741	Belongs to the pirin family
KFB96_00460	COG1979	alcohol dehydrogenase
KFB96_00465	COG0481	GTPase activity
KFB96_00470	COG0681	Belongs to the peptidase S26 family
KFB96_00480	COG0571	ribonuclease III activity
KFB96_00495	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KFB96_00500	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KFB96_00510	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
KFB96_00545	COG3077	Addiction module antitoxin, RelB DinJ family
KFB96_00555	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KFB96_00685	COG0483	inositol monophosphate 1-phosphatase activity
KFB96_00690	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
KFB96_00690	COG0662	Cupin 2, conserved barrel domain protein
KFB96_00695	COG0012	GTP binding
KFB96_00720	COG0028	Belongs to the TPP enzyme family
KFB96_00730	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
KFB96_00750	COG1272	protein, Hemolysin III
KFB96_00755	COG1686	Belongs to the peptidase S11 family
KFB96_00760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KFB96_00765	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KFB96_00775	COG1301	dicarboxylic acid transport
KFB96_00795	COG0670	Belongs to the BI1 family
KFB96_00805	COG3132	Protein of unknown function, DUF480
KFB96_00820	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KFB96_00840	COG0129	dihydroxy-acid dehydratase activity
KFB96_00885	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KFB96_00900	COG1254	Belongs to the acylphosphatase family
KFB96_00910	COG1592	Rubrerythrin
KFB96_00925	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFB96_00930	COG0508	dehydrogenase complex catalyzes the overall conversion of
KFB96_00950	COG1797	cobyrinic acid a,c-diamide synthase activity
KFB96_01020	COG3209	COG3209 Rhs family protein
KFB96_01060	COG2885	chlorophyll binding
KFB96_01110	COG1360	Flagellar Motor Protein
KFB96_01125	COG0631	protein serine/threonine phosphatase activity
KFB96_01140	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
KFB96_01200	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KFB96_01205	COG0302	gtp cyclohydrolase
KFB96_01210	COG0367	asparagine synthase
KFB96_01215	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KFB96_01215	COG0189	ligase activity
KFB96_01220	COG1363	Peptidase, m42
KFB96_01230	COG1346	cytolysis
KFB96_01250	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KFB96_01275	COG4536	flavin adenine dinucleotide binding
KFB96_01280	COG2974	May be involved in recombination
KFB96_01300	COG0497	DNA recombination
KFB96_01305	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KFB96_01310	COG1420	regulation of RNA biosynthetic process
KFB96_01315	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
KFB96_01320	COG0443	Heat shock 70 kDa protein
KFB96_01325	COG0484	heat shock protein binding
KFB96_01330	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
KFB96_01345	COG4783	chaperone-mediated protein folding
KFB96_01355	COG1858	cytochrome C peroxidase
KFB96_01375	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KFB96_01385	COG1106	Psort location Cytoplasmic, score
KFB96_01435	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KFB96_01440	COG1881	PFAM PEBP family protein
KFB96_01450	COG3088	subunit of a heme lyase
KFB96_01455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFB96_01465	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
KFB96_01475	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KFB96_01480	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
KFB96_01485	COG4133	protoheme IX ABC transporter activity
KFB96_01525	COG0471	metal ion transport
KFB96_01525	COG3273	potassium ion transport
KFB96_01535	COG3128	pkhd-type hydroxylase
KFB96_01540	COG0628	permease
KFB96_01545	COG1874	Beta-galactosidase
KFB96_01545	COG0366	Alpha amylase catalytic
KFB96_01560	COG0826	peptidase U32
KFB96_01565	COG2983	Belongs to the UPF0260 family
KFB96_01570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KFB96_01575	COG4974	Belongs to the 'phage' integrase family
KFB96_01580	COG1666	GTP binding
KFB96_01640	COG1943	Transposase
KFB96_01660	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
KFB96_01670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFB96_01670	COG3453	Protein conserved in bacteria
KFB96_01685	COG0730	response to heat
KFB96_01690	COG1131	(ABC) transporter
KFB96_01695	COG0842	Transport permease protein
KFB96_01700	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFB96_01710	COG1199	ATP-dependent helicase activity
KFB96_01740	COG0360	Binds together with S18 to 16S ribosomal RNA
KFB96_01755	COG0359	binds to the 23S rRNA
KFB96_01765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFB96_01770	COG2027	D-alanyl-D-alanine carboxypeptidase
KFB96_01780	COG2226	methyltransferase
KFB96_01785	COG0596	Alpha beta hydrolase
KFB96_01790	COG0156	8-amino-7-oxononanoate synthase activity
KFB96_01795	COG1028	Short-chain dehydrogenase reductase Sdr
KFB96_01805	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KFB96_01820	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
KFB96_01825	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KFB96_01830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFB96_01830	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KFB96_01845	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
KFB96_01850	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
KFB96_01855	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KFB96_01860	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KFB96_01865	COG0589	response to stress
KFB96_01895	COG0617	tRNA 3'-terminal CCA addition
KFB96_01930	COG2814	Major facilitator Superfamily
KFB96_01940	COG1902	pentaerythritol trinitrate reductase activity
KFB96_01950	COG3344	reverse transcriptase
KFB96_01965	COG1598	PFAM Uncharacterised protein family UPF0150
KFB96_02035	COG4969	Belongs to the N-Me-Phe pilin family
KFB96_02060	COG1943	Transposase
KFB96_02085	COG2258	MOSC domain
KFB96_02100	COG0436	Aminotransferase
KFB96_02130	COG1131	(ABC) transporter
KFB96_02140	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFB96_02145	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KFB96_02205	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KFB96_02215	COG0802	atpase or kinase
KFB96_02220	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFB96_02235	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
KFB96_02240	COG1923	regulation of RNA biosynthetic process
KFB96_02245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KFB96_02250	COG0330	HflC and HflK could
KFB96_02255	COG0330	HflC and HflK could
KFB96_02265	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
KFB96_02270	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KFB96_02280	COG0511	ligase activity, forming carbon-carbon bonds
KFB96_02280	COG5016	pyruvate
KFB96_02285	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
KFB96_02300	COG0416	fatty acid biosynthetic process
KFB96_02305	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFB96_02320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFB96_02325	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KFB96_02335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KFB96_02340	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
KFB96_02355	COG0084	hydrolase, TatD family'
KFB96_02365	COG0704	Plays a role in the regulation of phosphate uptake
KFB96_02375	COG0330	HflC and HflK could
KFB96_02395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
KFB96_02400	COG2954	triphosphatase activity
KFB96_02415	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KFB96_02425	COG0308	aminopeptidase N
KFB96_02445	COG1177	transmembrane transport
KFB96_02455	COG3842	ATPase activity
KFB96_02470	COG0107	imidazoleglycerol-phosphate synthase activity
KFB96_02480	COG2878	Part of a membrane complex involved in electron transport
KFB96_02480	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
KFB96_02485	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KFB96_02485	COG1013	pyruvate-flavodoxin oxidoreductase activity
KFB96_02485	COG0674	pyruvate-flavodoxin oxidoreductase activity
KFB96_02485	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KFB96_02490	COG4656	Part of a membrane complex involved in electron transport
KFB96_02495	COG4658	electron transport chain
KFB96_02505	COG4660	Part of a membrane complex involved in electron transport
KFB96_02510	COG4657	Part of a membrane complex involved in electron transport
KFB96_02520	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KFB96_02550	COG3093	addiction module antidote protein HigA
KFB96_02620	COG3243	poly(R)-hydroxyalkanoic acid synthase
KFB96_02660	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KFB96_02665	COG0581	inorganic phosphate transmembrane transporter activity
KFB96_02695	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KFB96_02700	COG0442	prolyl-tRNA aminoacylation
KFB96_02710	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
KFB96_02720	COG5001	Diguanylate cyclase
KFB96_02720	COG5002	protein histidine kinase activity
KFB96_02725	COG0488	(ABC) transporter
KFB96_02730	COG1763	Mo-molybdopterin cofactor biosynthetic process
KFB96_02785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KFB96_02790	COG0860	N-Acetylmuramoyl-L-alanine amidase
KFB96_02795	COG0515	serine threonine protein kinase
KFB96_02795	COG2815	serine threonine protein kinase
KFB96_02805	COG2815	serine threonine protein kinase
KFB96_02805	COG0515	serine threonine protein kinase
KFB96_02810	COG0515	serine threonine protein kinase
KFB96_02810	COG2815	serine threonine protein kinase
KFB96_02825	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFB96_02955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KFB96_03060	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFB96_03095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KFB96_03125	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFB96_03130	COG1487	ribonuclease activity
KFB96_03165	COG2003	Belongs to the UPF0758 family
KFB96_03220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFB96_03225	COG0629	single-stranded DNA binding
KFB96_03235	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFB96_03270	COG3344	reverse transcriptase
KFB96_03275	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KFB96_03365	COG0582	viral genome integration into host DNA
KFB96_03405	COG1125	glycine betaine transport
KFB96_03405	COG0517	IMP dehydrogenase activity
KFB96_03420	COG0429	hydrolase of the alpha beta-hydrolase fold
KFB96_03425	COG1538	Outer membrane efflux protein
KFB96_03430	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
KFB96_03435	COG2814	Major facilitator Superfamily
KFB96_03495	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
KFB96_03500	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
KFB96_03505	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KFB96_03515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KFB96_03540	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KFB96_03545	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
KFB96_03570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KFB96_03615	COG1136	(ABC) transporter
KFB96_03615	COG0577	efflux transmembrane transporter activity
KFB96_03650	COG0557	exoribonuclease II activity
KFB96_03655	COG3108	Peptidase M15
KFB96_03660	COG0741	lytic transglycosylase activity
KFB96_03670	COG2046	Belongs to the sulfate adenylyltransferase family
KFB96_03700	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
KFB96_03705	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
KFB96_03710	COG3437	response regulator, receiver
KFB96_03760	COG2944	sequence-specific DNA binding
KFB96_03780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFB96_03785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFB96_03805	COG0529	Catalyzes the synthesis of activated sulfate
KFB96_03820	COG3842	ATPase activity
KFB96_03825	COG1178	ABC-type Fe3 transport system permease component
KFB96_03830	COG1840	ABC-type Fe3 transport system, periplasmic component
KFB96_03835	COG0719	Fe-S assembly protein
KFB96_03840	COG0396	ATPase activity
KFB96_03845	COG0719	Fe-S assembly protein
KFB96_03850	COG2151	metal-sulfur cluster biosynthetic enzyme
KFB96_03860	COG0586	Pfam SNARE associated Golgi protein
KFB96_03865	COG1968	undecaprenyl-diphosphatase activity
KFB96_03880	COG2183	response to ionizing radiation
KFB96_03890	COG2203	Gaf domain
KFB96_03890	COG5001	Diguanylate cyclase
KFB96_03890	COG4251	negative regulation of phosphorylation
KFB96_03890	COG3706	GGDEF domain
KFB96_03915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFB96_04060	COG1546	Belongs to the CinA family
KFB96_04065	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
KFB96_04075	COG2137	regulation of response to DNA damage stimulus
KFB96_04080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
KFB96_04090	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
KFB96_04100	COG3609	addiction module antidote protein, CC2985 family
KFB96_04105	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KFB96_04135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KFB96_04150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFB96_04260	COG1047	Peptidyl-prolyl cis-trans
KFB96_04275	COG1047	Peptidyl-prolyl cis-trans
KFB96_04280	COG4191	Histidine kinase
KFB96_04290	COG3220	belongs to the UPF0276 family
KFB96_04330	COG1132	(ABC) transporter
KFB96_04340	COG0438	transferase activity, transferring glycosyl groups
KFB96_04350	COG5002	protein histidine kinase activity
KFB96_04355	COG0745	RESPONSE REGULATOR receiver
KFB96_04360	COG1331	Highly conserved protein containing a thioredoxin domain
KFB96_04365	COG4636	protein conserved in cyanobacteria
KFB96_04380	COG0069	glutamate synthase activity
KFB96_04390	COG2204	response regulator
KFB96_04430	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFB96_04455	COG0398	Pfam SNARE associated Golgi protein
KFB96_04490	COG3162	membrane
KFB96_04495	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KFB96_04535	COG0519	Catalyzes the synthesis of GMP from XMP
KFB96_04600	COG0167	dihydroorotate dehydrogenase activity
KFB96_04605	COG0674	pyruvate-flavodoxin oxidoreductase activity
KFB96_04605	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KFB96_04605	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KFB96_04605	COG1013	pyruvate-flavodoxin oxidoreductase activity
KFB96_04615	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KFB96_04755	COG0438	transferase activity, transferring glycosyl groups
KFB96_04930	COG3549	Plasmid maintenance system killer
KFB96_04940	COG3344	reverse transcriptase
KFB96_04980	COG1720	tRNA m6t6A37 methyltransferase activity
KFB96_04985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KFB96_04990	COG0557	exoribonuclease II activity
KFB96_05005	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
KFB96_05010	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
KFB96_05020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFB96_05035	COG0730	response to heat
KFB96_05060	COG1342	Belongs to the UPF0251 family
KFB96_05070	COG0489	protein tyrosine kinase activity
KFB96_05085	COG1234	tRNA 3'-trailer cleavage
KFB96_05100	COG2925	Exonuclease
KFB96_05115	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KFB96_05120	COG0228	four-way junction DNA binding
KFB96_05140	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KFB96_05150	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
KFB96_05155	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFB96_05170	COG2166	iron-sulfur cluster assembly
KFB96_05175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFB96_05190	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFB96_05195	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFB96_05200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KFB96_05205	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFB96_05210	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
KFB96_05215	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KFB96_05220	COG0750	zinc metalloprotease
KFB96_05225	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
KFB96_05235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KFB96_05240	COG0233	cytoplasmic translational termination
KFB96_05245	COG0528	UMP kinase activity
KFB96_05250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
KFB96_05255	COG0052	Belongs to the universal ribosomal protein uS2 family
KFB96_05260	COG0024	Methionine aminopeptidase
KFB96_05265	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KFB96_05280	COG0436	Aminotransferase
KFB96_05285	COG2171	N-acyltransferase activity
KFB96_05290	COG1393	Belongs to the ArsC family
KFB96_05295	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KFB96_05385	COG2204	response regulator
KFB96_05405	COG2204	response regulator
KFB96_05410	COG4191	Histidine kinase
KFB96_05430	COG0243	molybdopterin cofactor binding
KFB96_05435	COG0437	4 iron, 4 sulfur cluster binding
KFB96_05470	COG0243	molybdopterin cofactor binding
KFB96_05485	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KFB96_05490	COG1185	polyribonucleotide nucleotidyltransferase activity
KFB96_05495	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
KFB96_05500	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KFB96_05505	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
KFB96_05510	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
KFB96_05515	COG0195	Participates in both transcription termination and antitermination
KFB96_05525	COG3091	SprT-like family
KFB96_05545	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KFB96_05550	COG1472	Belongs to the glycosyl hydrolase 3 family
KFB96_05560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFB96_05565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFB96_05570	COG0424	maF-like protein
KFB96_05575	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KFB96_05590	COG0045	succinate-CoA ligase (ADP-forming) activity
KFB96_05590	COG1042	CoA-binding domain protein
KFB96_05590	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
KFB96_05595	COG0123	including yeast histone deacetylase and acetoin utilization protein
KFB96_05605	COG0415	Belongs to the DNA photolyase family
KFB96_05610	COG0659	secondary active sulfate transmembrane transporter activity
KFB96_05615	COG0084	hydrolase, TatD family'
KFB96_05625	COG3122	Protein conserved in bacteria
KFB96_05640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFB96_05660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KFB96_05710	COG5654	RES domain protein
KFB96_05715	COG5642	Protein of unknown function (DUF2384)
KFB96_05755	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KFB96_05760	COG2226	methyltransferase
KFB96_05765	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KFB96_05805	COG2161	toxin-antitoxin pair type II binding
KFB96_05810	COG2026	Addiction module toxin, RelE StbE family
KFB96_05855	COG2801	Transposase and inactivated derivatives
KFB96_05855	COG3415	Transposase
KFB96_05860	COG3267	Type II secretory pathway component ExeA
KFB96_05860	COG3409	Peptidoglycan-binding domain 1 protein
KFB96_05875	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KFB96_05905	COG2801	Transposase and inactivated derivatives
KFB96_05905	COG3415	Transposase
KFB96_05910	COG3267	Type II secretory pathway component ExeA
KFB96_05910	COG3409	Peptidoglycan-binding domain 1 protein
KFB96_05935	COG2944	sequence-specific DNA binding
KFB96_06075	COG2944	sequence-specific DNA binding
KFB96_06150	COG2944	sequence-specific DNA binding
KFB96_06170	COG3657	addiction module killer protein
KFB96_06180	COG3344	reverse transcriptase
KFB96_06190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFB96_06195	COG4464	protein tyrosine phosphatase activity
KFB96_06235	COG0489	protein tyrosine kinase activity
KFB96_06250	COG1434	Gram-negative-bacterium-type cell wall biogenesis
KFB96_06295	COG1063	alcohol dehydrogenase
KFB96_06315	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KFB96_06320	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KFB96_06330	COG0454	-acetyltransferase
KFB96_06330	COG0456	acetyltransferase
KFB96_06335	COG0463	Glycosyl transferase, family 2
KFB96_06390	COG0297	glycogen (starch) synthase activity
KFB96_06390	COG0438	transferase activity, transferring glycosyl groups
KFB96_06395	COG0438	transferase activity, transferring glycosyl groups
KFB96_06410	COG0438	transferase activity, transferring glycosyl groups
KFB96_06415	COG1216	Glycosyl transferase, family 2
KFB96_06460	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
KFB96_06480	COG0673	inositol 2-dehydrogenase activity
KFB96_06485	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
KFB96_06495	COG1083	cytidylyl-transferase
KFB96_06500	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KFB96_06505	COG1028	Short-chain dehydrogenase reductase Sdr
KFB96_06580	COG0318	PFAM AMP-dependent synthetase and ligase
KFB96_06590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KFB96_06610	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KFB96_06640	COG4133	protoheme IX ABC transporter activity
KFB96_06670	COG3311	Transcriptional regulator
KFB96_06700	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KFB96_06715	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFB96_06720	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KFB96_06740	COG1598	PFAM Uncharacterised protein family UPF0150
KFB96_06770	COG2089	acid synthase
KFB96_06775	COG2089	acid synthase
KFB96_06785	COG2089	acid synthase
KFB96_06790	COG2089	acid synthase
KFB96_06800	COG2089	acid synthase
KFB96_06805	COG2089	acid synthase
KFB96_06820	COG2089	acid synthase
KFB96_06975	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KFB96_06975	COG0517	IMP dehydrogenase activity
KFB96_07000	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KFB96_07020	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KFB96_07135	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KFB96_07155	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFB96_07220	COG3093	addiction module antidote protein HigA
KFB96_07275	COG5654	RES domain protein
KFB96_07325	COG3335	DDE superfamily endonuclease
KFB96_07355	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KFB96_07410	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFB96_07420	COG1136	(ABC) transporter
KFB96_07450	COG3956	TIGRFAM MazG family protein
KFB96_07460	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
KFB96_07490	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KFB96_07495	COG1301	dicarboxylic acid transport
KFB96_07530	COG0277	FAD linked oxidase domain protein
KFB96_07535	COG1242	4 iron, 4 sulfur cluster binding
KFB96_07540	COG0826	peptidase U32
KFB96_07545	COG0826	peptidase U32
KFB96_07550	COG3154	lipid carrier protein
KFB96_07555	COG0741	lytic transglycosylase activity
KFB96_07565	COG3409	Peptidoglycan-binding domain 1 protein
KFB96_07565	COG3267	Type II secretory pathway component ExeA
KFB96_07570	COG1132	(ABC) transporter
KFB96_07580	COG1216	Glycosyl transferase, family 2
KFB96_07580	COG1442	glycosyl transferase family 8
KFB96_07585	COG1215	transferase activity, transferring glycosyl groups
KFB96_07605	COG0367	asparagine synthase
KFB96_07620	COG2226	methyltransferase
KFB96_07725	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
KFB96_07735	COG1088	dTDP-glucose 4,6-dehydratase activity
KFB96_07740	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
KFB96_07765	COG2133	pyrroloquinoline quinone binding
KFB96_07795	COG1216	Glycosyl transferase, family 2
KFB96_07795	COG0463	Glycosyl transferase, family 2
KFB96_07815	COG1215	transferase activity, transferring glycosyl groups
KFB96_07820	COG1215	transferase activity, transferring glycosyl groups
KFB96_07855	COG1610	YqeY-like protein
KFB96_07860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
KFB96_07880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KFB96_07895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFB96_07920	COG2210	Belongs to the sulfur carrier protein TusA family
KFB96_07925	COG0425	Belongs to the sulfur carrier protein TusA family
KFB96_07930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KFB96_07935	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KFB96_07935	COG1648	precorrin-2 dehydrogenase activity
KFB96_07940	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
KFB96_07945	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KFB96_07980	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
KFB96_08000	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
KFB96_08020	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
KFB96_08025	COG1993	acr, cog1993
KFB96_08030	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
KFB96_08070	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KFB96_08085	COG0584	glycerophosphoryl diester phosphodiesterase
KFB96_08090	COG3263	regulation of cellular component size
KFB96_08095	COG0589	response to stress
KFB96_08125	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
KFB96_08140	COG4191	Histidine kinase
KFB96_08145	COG1192	Involved in chromosome partitioning
KFB96_08160	COG0038	chloride channel
KFB96_08195	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KFB96_08215	COG4804	nuclease activity
KFB96_08240	COG2716	regulation of RNA biosynthetic process
KFB96_08245	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KFB96_08250	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
KFB96_08310	COG2223	nitrite transmembrane transporter activity
KFB96_08315	COG0659	secondary active sulfate transmembrane transporter activity
KFB96_08320	COG3447	MASE1 domain protein
KFB96_08320	COG5001	Diguanylate cyclase
KFB96_08320	COG5002	protein histidine kinase activity
KFB96_08365	COG0776	regulation of translation
KFB96_08375	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
KFB96_08385	COG0291	Belongs to the bacterial ribosomal protein bL35 family
KFB96_08395	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
KFB96_08410	COG0604	alcohol dehydrogenase
KFB96_08430	COG0420	3'-5' exonuclease activity
KFB96_08445	COG0438	transferase activity, transferring glycosyl groups
KFB96_08470	COG2943	transferase activity, transferring hexosyl groups
KFB96_08490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KFB96_08495	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KFB96_08505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KFB96_08510	COG3909	cytochrome
KFB96_08555	COG2066	Belongs to the glutaminase family
KFB96_08555	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
KFB96_08560	COG1040	competence protein
KFB96_08565	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
KFB96_08575	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KFB96_08580	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
KFB96_08585	COG1509	lysine 2,3-aminomutase activity
KFB96_08605	COG0489	protein tyrosine kinase activity
KFB96_08635	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KFB96_08640	COG3005	denitrification pathway
KFB96_08650	COG2863	cytochrome
KFB96_08655	COG0446	pyridine nucleotide-disulphide oxidoreductase
KFB96_08690	COG1320	monovalent cation:proton antiporter activity
KFB96_08715	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFB96_08720	COG0651	ATP synthesis coupled electron transport
KFB96_08745	COG4946	Tricorn protease homolog
KFB96_08745	COG1506	peptidase
KFB96_08745	COG0823	Involved in the tonB-independent uptake of proteins
KFB96_08770	COG0542	response to heat
KFB96_08795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KFB96_08800	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KFB96_08865	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KFB96_08880	COG2205	protein histidine kinase activity
KFB96_08880	COG0784	Response regulator, receiver
KFB96_08880	COG5002	protein histidine kinase activity
KFB96_08900	COG0450	alkyl hydroperoxide reductase
KFB96_08925	COG3335	DDE superfamily endonuclease
KFB96_08935	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KFB96_08950	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KFB96_09010	COG0628	permease
KFB96_09015	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFB96_09080	COG2226	methyltransferase
KFB96_09105	COG3263	regulation of cellular component size
KFB96_09120	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KFB96_09140	COG4636	protein conserved in cyanobacteria
KFB96_09155	COG1196	nuclear chromosome segregation
KFB96_09200	COG1858	cytochrome C peroxidase
KFB96_09210	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KFB96_09215	COG1053	succinate dehydrogenase
KFB96_09220	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KFB96_09235	COG1560	Kdo2-lipid A biosynthetic process
KFB96_09255	COG0837	glucose binding
KFB96_09280	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KFB96_09285	COG0310	cobalt ion transport
KFB96_09295	COG0864	Transcriptional regulator
KFB96_09310	COG2308	Evidence 4 Homologs of previously reported genes of
KFB96_09325	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KFB96_09330	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KFB96_09360	COG2337	Toxic component of a toxin-antitoxin (TA) module
KFB96_09365	COG2336	PFAM SpoVT AbrB
KFB96_09430	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KFB96_09440	COG3344	reverse transcriptase
KFB96_09455	COG3344	reverse transcriptase
KFB96_09485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFB96_09495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFB96_09510	COG1136	(ABC) transporter
KFB96_09600	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
KFB96_09605	COG1070	Carbohydrate kinase
KFB96_09610	COG5001	Diguanylate cyclase
KFB96_09610	COG3300	MHYT domain
KFB96_09615	COG0287	Prephenate dehydrogenase
KFB96_09620	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KFB96_09635	COG0077	Prephenate dehydratase
KFB96_09635	COG1605	Chorismate mutase
KFB96_09640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KFB96_09645	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KFB96_09660	COG0513	Belongs to the DEAD box helicase family
KFB96_09675	COG0203	ribosomal protein L17
KFB96_09680	COG0202	RNA polymerase activity
KFB96_09685	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
KFB96_09690	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
KFB96_09695	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
KFB96_09700	COG0257	Belongs to the bacterial ribosomal protein bL36 family
KFB96_09705	COG0201	protein transport
KFB96_09710	COG0200	Binds to the 23S rRNA
KFB96_09715	COG1841	ribosomal large subunit assembly
KFB96_09720	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
KFB96_09725	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
KFB96_09735	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
KFB96_09740	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
KFB96_09745	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
KFB96_09750	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
KFB96_09755	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
KFB96_09760	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
KFB96_09765	COG0255	Belongs to the universal ribosomal protein uL29 family
KFB96_09770	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
KFB96_09775	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
KFB96_09780	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
KFB96_09785	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
KFB96_09790	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
KFB96_09795	COG0089	rRNA binding
KFB96_09805	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
KFB96_09810	COG0051	transcription antitermination factor activity, RNA binding
KFB96_09820	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KFB96_09825	COG0049	tRNA binding
KFB96_09830	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
KFB96_09835	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
KFB96_09840	COG0085	RNA polymerase activity
KFB96_09845	COG0222	ribosome binding
KFB96_09850	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
KFB96_09855	COG0081	regulation of translation
KFB96_09860	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
KFB96_09910	COG0193	aminoacyl-tRNA hydrolase activity
KFB96_09915	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
KFB96_09920	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KFB96_09930	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
KFB96_09945	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
KFB96_09950	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
KFB96_09975	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
KFB96_09985	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KFB96_10030	COG3609	addiction module antidote protein, CC2985 family
KFB96_10040	COG1104	cysteine desulfurase activity
KFB96_10050	COG1598	PFAM Uncharacterised protein family UPF0150
KFB96_10060	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KFB96_10105	COG0598	Magnesium transport protein CorA
KFB96_10110	COG3302	dmso reductase anchor subunit
KFB96_10115	COG0437	4 iron, 4 sulfur cluster binding
KFB96_10130	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
KFB96_10140	COG0488	(ABC) transporter
KFB96_10165	COG1294	oxidase, subunit
KFB96_10170	COG4890	Cyd operon protein YbgT
KFB96_10190	COG2336	PFAM SpoVT AbrB
KFB96_10245	COG0772	Belongs to the SEDS family
KFB96_10250	COG2944	sequence-specific DNA binding
KFB96_10285	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
KFB96_10290	COG1663	tetraacyldisaccharide 4'-kinase activity
KFB96_10295	COG1132	(ABC) transporter
KFB96_10300	COG0848	biopolymer transport protein
KFB96_10305	COG0811	peptide transport
KFB96_10310	COG1704	LemA family
KFB96_10315	COG0501	Belongs to the peptidase M48B family
KFB96_10330	COG0463	Glycosyl transferase, family 2
KFB96_10335	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
KFB96_10360	COG3046	protein related to deoxyribodipyrimidine photolyase
KFB96_10370	COG0386	Belongs to the glutathione peroxidase family
KFB96_10390	COG0501	Belongs to the peptidase M48B family
KFB96_10495	COG0616	signal peptide processing
KFB96_10500	COG0546	phosphoglycolate phosphatase activity
KFB96_10505	COG0564	pseudouridine synthase activity
KFB96_10510	COG1530	ribonuclease E activity
KFB96_10530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KFB96_10540	COG0438	transferase activity, transferring glycosyl groups
KFB96_10545	COG0561	phosphatase activity
KFB96_10545	COG3100	YcgL domain-containing protein
KFB96_10580	COG0616	signal peptide processing
KFB96_10585	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
KFB96_10590	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KFB96_10595	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KFB96_10620	COG1797	cobyrinic acid a,c-diamide synthase activity
KFB96_10655	COG2920	part of a sulfur-relay system
KFB96_10660	COG2168	tRNA wobble position uridine thiolation
KFB96_10665	COG2923	Belongs to the DsrF TusC family
KFB96_10670	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KFB96_10675	COG2221	Nitrite and sulphite reductase 4Fe-4S
KFB96_10680	COG2221	Nitrite and sulphite reductase 4Fe-4S
KFB96_10705	COG2920	part of a sulfur-relay system
KFB96_10715	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KFB96_10730	COG3604	Transcriptional regulator
KFB96_10740	COG0310	cobalt ion transport
KFB96_10770	COG2814	Major facilitator Superfamily
KFB96_10775	COG2193	ferroxidase activity
KFB96_10815	COG1131	(ABC) transporter
KFB96_10840	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KFB96_10865	COG2161	toxin-antitoxin pair type II binding
KFB96_10905	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
KFB96_10970	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KFB96_10990	COG1690	Belongs to the RtcB family
KFB96_11015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFB96_11030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFB96_11035	COG0471	metal ion transport
KFB96_11035	COG0490	domain, Protein
KFB96_11040	COG0471	metal ion transport
KFB96_11040	COG0490	domain, Protein
KFB96_11065	COG0446	pyridine nucleotide-disulphide oxidoreductase
KFB96_11070	COG0446	pyridine nucleotide-disulphide oxidoreductase
KFB96_11110	COG0028	Belongs to the TPP enzyme family
KFB96_11135	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KFB96_11160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KFB96_11190	COG3273	potassium ion transport
KFB96_11190	COG0471	metal ion transport
KFB96_11195	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFB96_11295	COG1643	Atp-dependent helicase
KFB96_11335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KFB96_11365	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KFB96_11380	COG0735	belongs to the Fur family
KFB96_11390	COG2914	Belongs to the UPF0125 (RnfH) family
KFB96_11395	COG2867	negative regulation of translational initiation
KFB96_11400	COG0733	neurotransmitter:sodium symporter activity
KFB96_11405	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFB96_11410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KFB96_11415	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KFB96_11430	COG0791	NLP P60 protein
KFB96_11440	COG0492	ferredoxin-NADP+ reductase activity
KFB96_11450	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KFB96_11455	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
KFB96_11460	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
KFB96_11465	COG0542	response to heat
KFB96_11470	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KFB96_11475	COG1278	Cold shock
KFB96_11485	COG0482	sulfurtransferase activity
KFB96_11490	COG2915	High frequency lysogenization protein hflD homolog
KFB96_11520	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KFB96_11525	COG4566	intracellular signal transduction
KFB96_11530	COG4191	Histidine kinase
KFB96_11540	COG0795	lipopolysaccharide-transporting ATPase activity
KFB96_11545	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
KFB96_11570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KFB96_11645	COG0745	RESPONSE REGULATOR receiver
KFB96_11655	COG3260	NADH ubiquinone oxidoreductase 20
KFB96_11670	COG0649	NAD binding
KFB96_11675	COG0651	ATP synthesis coupled electron transport
KFB96_11685	COG0650	Formate hydrogenlyase subunit 4
KFB96_11690	COG0651	ATP synthesis coupled electron transport
KFB96_11720	COG3045	CreA protein
KFB96_11740	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
KFB96_11745	COG1120	ATPase activity
KFB96_11775	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
KFB96_11780	COG2205	protein histidine kinase activity
KFB96_11780	COG5002	protein histidine kinase activity
KFB96_11780	COG0784	Response regulator, receiver
KFB96_11785	COG0776	regulation of translation
KFB96_11795	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
KFB96_11800	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KFB96_11840	COG0583	DNA-binding transcription factor activity
KFB96_11880	COG0714	Associated with various cellular activities
KFB96_11885	COG0546	phosphoglycolate phosphatase activity
KFB96_11895	COG0583	DNA-binding transcription factor activity
KFB96_11925	COG0137	argininosuccinate synthase activity
KFB96_11940	COG2133	pyrroloquinoline quinone binding
KFB96_11950	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
KFB96_11985	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KFB96_11990	COG3620	sequence-specific DNA binding
KFB96_11990	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
KFB96_11990	COG0617	tRNA 3'-terminal CCA addition
KFB96_12000	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KFB96_12025	COG0237	dephospho-CoA kinase activity
KFB96_12065	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
KFB96_12075	COG0261	This protein binds to 23S rRNA in the presence of protein L20
KFB96_12080	COG0142	geranyltranstransferase activity
KFB96_12090	COG2211	Major facilitator Superfamily
KFB96_12095	COG5001	Diguanylate cyclase
KFB96_12095	COG3300	MHYT domain
KFB96_12100	COG3830	Belongs to the UPF0237 family
KFB96_12100	COG0560	Phosphoserine phosphatase
KFB96_12105	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KFB96_12125	COG0312	modulator of DNA gyrase
KFB96_12130	COG0312	modulator of DNA gyrase
KFB96_12155	COG0424	maF-like protein
KFB96_12160	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
KFB96_12165	COG1410	methionine synthase
KFB96_12165	COG0646	methionine synthase
KFB96_12180	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KFB96_12195	COG4115	mRNA cleavage
KFB96_12220	COG2337	Toxic component of a toxin-antitoxin (TA) module
KFB96_12250	COG3609	addiction module antidote protein, CC2985 family
KFB96_12295	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
KFB96_12315	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KFB96_12335	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KFB96_12350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KFB96_12355	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KFB96_12360	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
KFB96_12370	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KFB96_12375	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KFB96_12385	COG0126	phosphoglycerate kinase activity
KFB96_12390	COG0469	pyruvate kinase activity
KFB96_12410	COG0259	pyridoxamine-phosphate oxidase activity
KFB96_12450	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KFB96_12455	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
KFB96_12465	COG4907	membrane protein (DUF2207)
KFB96_12470	COG1704	LemA family
KFB96_12475	COG0741	lytic transglycosylase activity
KFB96_12485	COG0688	phosphatidylethanolamine metabolic process
KFB96_12495	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFB96_12505	COG4067	protein conserved in archaea
KFB96_12505	COG0189	ligase activity
KFB96_12515	COG2308	Evidence 4 Homologs of previously reported genes of
KFB96_12530	COG0784	Response regulator, receiver
KFB96_12530	COG2205	protein histidine kinase activity
KFB96_12530	COG5002	protein histidine kinase activity
KFB96_12535	COG1295	ribonuclease BN
KFB96_12540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFB96_12545	COG0784	Response regulator, receiver
KFB96_12545	COG2205	protein histidine kinase activity
KFB96_12545	COG5002	protein histidine kinase activity
KFB96_12550	COG4999	Histidine kinase
KFB96_12550	COG3850	Histidine kinase
KFB96_12550	COG3437	response regulator, receiver
KFB96_12550	COG2205	protein histidine kinase activity
KFB96_12555	COG3437	response regulator, receiver
KFB96_12565	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KFB96_12570	COG2161	toxin-antitoxin pair type II binding
KFB96_12580	COG1943	Transposase
KFB96_12630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KFB96_12645	COG2918	glutathione biosynthetic process
KFB96_12650	COG0793	Belongs to the peptidase S41A family
KFB96_12655	COG0242	peptide deformylase activity
KFB96_12660	COG3830	Belongs to the UPF0237 family
KFB96_12680	COG0347	Belongs to the P(II) protein family
KFB96_12690	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
KFB96_12695	COG0045	succinate-CoA ligase (ADP-forming) activity
KFB96_12710	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KFB96_12710	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KFB96_12715	COG1511	domain protein
KFB96_12715	COG3264	Mechanosensitive ion channel
KFB96_12730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KFB96_12735	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KFB96_12750	COG0284	orotidine-5'-phosphate decarboxylase activity
KFB96_12755	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
KFB96_12760	COG1028	Short-chain dehydrogenase reductase Sdr
KFB96_12780	COG1283	sodium-dependent phosphate transmembrane transporter activity
KFB96_12795	COG1132	(ABC) transporter
KFB96_12815	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
KFB96_12835	COG0300	oxidoreductase activity
KFB96_12840	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFB96_12845	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
KFB96_12850	COG0505	Belongs to the CarA family
KFB96_12860	COG3118	belongs to the thioredoxin family
KFB96_12865	COG0037	tRNA processing
KFB96_12870	COG0825	malonyl-CoA metabolic process
KFB96_12885	COG1136	(ABC) transporter
KFB96_12900	COG1570	exodeoxyribonuclease VII activity
KFB96_12910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KFB96_12910	COG0519	Catalyzes the synthesis of GMP from XMP
KFB96_12915	COG1106	Psort location Cytoplasmic, score
KFB96_12990	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFB96_13000	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KFB96_13005	COG0708	Exodeoxyribonuclease III
KFB96_13025	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KFB96_13030	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
KFB96_13035	COG1850	ribulose-bisphosphate carboxylase activity
KFB96_13090	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KFB96_13095	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KFB96_13100	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
KFB96_13105	COG1063	alcohol dehydrogenase
KFB96_13110	COG0500	methyltransferase
KFB96_13115	COG0142	geranyltranstransferase activity
KFB96_13145	COG2814	Major facilitator Superfamily
KFB96_13150	COG0500	methyltransferase
KFB96_13195	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KFB96_13200	COG2124	cytochrome p450
KFB96_13215	COG0318	PFAM AMP-dependent synthetase and ligase
KFB96_13220	COG1719	4-vinyl reductase, 4VR
KFB96_13225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFB96_13260	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
KFB96_13265	COG1429	ligase activity, forming nitrogen-metal bonds
KFB96_13270	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KFB96_13275	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
KFB96_13290	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KFB96_13295	COG0644	oxidoreductase
KFB96_13320	COG0582	viral genome integration into host DNA
KFB96_13400	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
KFB96_13405	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
KFB96_13405	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
KFB96_13415	COG0724	RNA recognition motif
KFB96_13420	COG0513	Belongs to the DEAD box helicase family
KFB96_13430	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
KFB96_13435	COG3876	Protein conserved in bacteria
KFB96_13445	COG0745	RESPONSE REGULATOR receiver
KFB96_13495	COG2084	Dehydrogenase
KFB96_13500	COG0247	lactate metabolic process
KFB96_13505	COG0277	FAD linked oxidase domain protein
KFB96_13510	COG0632	four-way junction helicase activity
KFB96_13515	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
KFB96_13520	COG0217	transcriptional regulatory protein
KFB96_13535	COG2226	methyltransferase
KFB96_13545	COG2226	methyltransferase
KFB96_13550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFB96_13565	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KFB96_13585	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KFB96_13600	COG1028	Short-chain dehydrogenase reductase Sdr
KFB96_13605	COG0463	Glycosyl transferase, family 2
KFB96_13620	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFB96_13630	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
KFB96_13640	COG0494	nUDIX hydrolase
KFB96_13645	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KFB96_13650	COG0653	protein targeting
KFB96_13655	COG0739	heme binding
KFB96_13665	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
KFB96_13680	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KFB96_13685	COG1181	Belongs to the D-alanine--D-alanine ligase family
KFB96_13690	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KFB96_13695	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFB96_13700	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
KFB96_13710	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
KFB96_13715	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFB96_13720	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KFB96_13725	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KFB96_13735	COG3116	cell division
KFB96_13740	COG0275	rRNA processing
KFB96_13745	COG2001	Belongs to the MraZ family
KFB96_13755	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
KFB96_13765	COG0792	nuclease activity
KFB96_13770	COG2823	Periplasmic or secreted lipoprotein
KFB96_13775	COG0277	FAD linked oxidase domain protein
KFB96_13780	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
KFB96_13785	COG0494	nUDIX hydrolase
KFB96_13810	COG0671	phosphoesterase, PA-phosphatase related
KFB96_13825	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KFB96_13855	COG3023	N-Acetylmuramoyl-L-alanine amidase
KFB96_13875	COG1183	phosphatidylcholine synthase activity
KFB96_13880	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
KFB96_13895	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
KFB96_13905	COG3259	Nickel-dependent hydrogenase
KFB96_13935	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KFB96_13945	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KFB96_13975	COG2814	Major facilitator Superfamily
KFB96_13985	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KFB96_13990	COG1785	Belongs to the alkaline phosphatase family
KFB96_14060	COG0514	ATP-dependent DNA helicase (RecQ)
KFB96_14065	COG0248	Ppx GppA phosphatase
KFB96_14075	COG1028	Short-chain dehydrogenase reductase Sdr
KFB96_14100	COG2154	pterin-4-alpha-carbinolamine dehydratase
KFB96_14130	COG0704	Plays a role in the regulation of phosphate uptake
KFB96_14135	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KFB96_14145	COG0573	inorganic phosphate transmembrane transporter activity
KFB96_14160	COG0438	transferase activity, transferring glycosyl groups
KFB96_14165	COG0717	Belongs to the dCTP deaminase family
KFB96_14170	COG0489	protein tyrosine kinase activity
KFB96_14175	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFB96_14175	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KFB96_14180	COG4657	Part of a membrane complex involved in electron transport
KFB96_14185	COG2878	Part of a membrane complex involved in electron transport
KFB96_14195	COG4658	electron transport chain
KFB96_14200	COG4659	FMN binding
KFB96_14205	COG4660	Part of a membrane complex involved in electron transport
KFB96_14215	COG3954	Phosphoribulokinase
KFB96_14220	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KFB96_14230	COG4535	Mg2 and Co2 transporter CorC
KFB96_14235	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
KFB96_14240	COG1702	phosphate starvation-inducible protein PhoH
KFB96_14245	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFB96_14295	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
KFB96_14300	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFB96_14315	COG0189	ligase activity
KFB96_14315	COG0569	domain protein
KFB96_14375	COG0165	Argininosuccinate lyase
KFB96_14395	COG0367	asparagine synthase
KFB96_14400	COG0438	transferase activity, transferring glycosyl groups
KFB96_14435	COG4772	TonB-dependent receptor
KFB96_14455	COG0247	lactate metabolic process
KFB96_14460	COG3657	addiction module killer protein
KFB96_14485	COG2203	Gaf domain
KFB96_14485	COG3706	GGDEF domain
KFB96_14485	COG4251	negative regulation of phosphorylation
KFB96_14485	COG5001	Diguanylate cyclase
KFB96_14490	COG0514	ATP-dependent DNA helicase (RecQ)
KFB96_14530	COG1376	ErfK ybiS ycfS ynhG family protein
KFB96_14535	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
KFB96_14545	COG3001	Fructosamine kinase
KFB96_14560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KFB96_14565	COG2197	response regulator
KFB96_14580	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KFB96_14645	COG0019	diaminopimelate decarboxylase activity
KFB96_14655	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KFB96_14665	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KFB96_14750	COG0210	DNA helicase
KFB96_14780	COG0629	single-stranded DNA binding
KFB96_14785	COG0653	protein targeting
KFB96_14850	COG0436	Aminotransferase
KFB96_14855	COG0556	nucleotide-excision repair
KFB96_14875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KFB96_14880	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KFB96_14905	COG2703	oxygen carrier activity
KFB96_14910	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KFB96_14915	COG1053	succinate dehydrogenase
KFB96_14920	COG2009	succinate dehydrogenase
KFB96_14925	COG0037	tRNA processing
KFB96_14940	COG3153	acetyltransferase
KFB96_14940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFB96_14945	COG4942	peptidase
KFB96_14995	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KFB96_15000	COG0071	Belongs to the small heat shock protein (HSP20) family
KFB96_15010	COG0204	Acyl-transferase
KFB96_15010	COG0318	PFAM AMP-dependent synthetase and ligase
KFB96_15025	COG0824	Thioesterase
KFB96_15035	COG4145	pantothenate transmembrane transporter activity
KFB96_15075	COG0298	carbon dioxide binding
KFB96_15080	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
KFB96_15095	COG4991	sh3 domain protein
KFB96_15105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KFB96_15110	COG3038	cytochrome b561
KFB96_15120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KFB96_15140	COG1652	LysM domain
KFB96_15145	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KFB96_15155	COG0443	Heat shock 70 kDa protein
KFB96_15195	COG1320	monovalent cation:proton antiporter activity
KFB96_15215	COG1007	ATP synthesis coupled electron transport
KFB96_15220	COG0651	ATP synthesis coupled electron transport
KFB96_15230	COG3920	Histidine kinase
KFB96_15255	COG0588	phosphoglycerate mutase activity
KFB96_15260	COG0704	Plays a role in the regulation of phosphate uptake
KFB96_15270	COG0018	arginyl-trna synthetase
KFB96_15275	COG0804	urea catabolic process
KFB96_15280	COG0832	Belongs to the urease beta subunit family
KFB96_15285	COG0831	urea catabolic process
KFB96_15290	COG0829	nickel cation binding
KFB96_15295	COG2885	chlorophyll binding
KFB96_15300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KFB96_15305	COG0280	phosphate acetyltransferase
KFB96_15305	COG0857	belongs to the CobB CobQ family
KFB96_15365	COG1201	RNA secondary structure unwinding
KFB96_15375	COG0494	nUDIX hydrolase
KFB96_15380	COG1011	Hydrolase
KFB96_15395	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
KFB96_15415	COG4636	protein conserved in cyanobacteria
KFB96_15420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
KFB96_15425	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KFB96_15430	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KFB96_15435	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KFB96_15450	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KFB96_15455	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KFB96_15460	COG1127	ABC transporter
KFB96_15480	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KFB96_15495	COG1137	ATPase activity
KFB96_15515	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
KFB96_15520	COG1660	Displays ATPase and GTPase activities
KFB96_15530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KFB96_15535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFB96_15540	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KFB96_15560	COG0315	cyclic pyranopterin monophosphate synthase activity
KFB96_15565	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KFB96_15570	COG0205	6-phosphofructokinase activity
KFB96_15575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFB96_15580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KFB96_15585	COG0006	proline dipeptidase activity
KFB96_15610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KFB96_15615	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KFB96_15620	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
KFB96_15640	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KFB96_15645	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
KFB96_15650	COG3411	Ferredoxin
KFB96_15660	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
KFB96_15665	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
KFB96_15680	COG0134	indole-3-glycerol-phosphate synthase activity
KFB96_15685	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KFB96_15705	COG4691	Plasmid stability protein
KFB96_15715	COG0546	phosphoglycolate phosphatase activity
KFB96_15720	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KFB96_15725	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
KFB96_15745	COG2205	protein histidine kinase activity
KFB96_15750	COG0745	RESPONSE REGULATOR receiver
KFB96_15760	COG0667	Aldo Keto reductase
KFB96_15775	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFB96_15780	COG0405	Gamma-glutamyltransferase
KFB96_15815	COG0668	transmembrane transport
KFB96_15820	COG0446	pyridine nucleotide-disulphide oxidoreductase
KFB96_15860	COG4636	protein conserved in cyanobacteria
KFB96_15885	COG0651	ATP synthesis coupled electron transport
KFB96_15900	COG1320	monovalent cation:proton antiporter activity
KFB96_15925	COG4566	intracellular signal transduction
KFB96_15980	COG2610	gluconate transmembrane transporter activity
KFB96_16005	COG0471	metal ion transport
KFB96_16005	COG0490	domain, Protein
KFB96_16010	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KFB96_16025	COG0786	glutamate:sodium symporter activity
KFB96_16030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFB96_16035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFB96_16055	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
KFB96_16095	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFB96_16135	COG1192	Involved in chromosome partitioning
KFB96_16170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KFB96_16175	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KFB96_16180	COG1047	Peptidyl-prolyl cis-trans
KFB96_16185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KFB96_16190	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
KFB96_16200	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
KFB96_16205	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
KFB96_16210	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
KFB96_16220	COG0356	it plays a direct role in the translocation of protons across the membrane
KFB96_16225	COG3312	ion transport
KFB96_16230	COG1475	DNA binding
KFB96_16235	COG1192	Involved in chromosome partitioning
KFB96_16245	COG0445	tRNA wobble uridine modification
KFB96_16250	COG0714	Associated with various cellular activities
KFB96_16345	COG3344	reverse transcriptase
KFB96_16370	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KFB96_16390	COG2084	Dehydrogenase
KFB96_16395	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KFB96_16425	COG1022	Amp-dependent synthetase and ligase
KFB96_16440	COG1194	a g-specific adenine glycosylase
KFB96_16445	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
KFB96_16450	COG1077	Cell shape determining protein MreB Mrl
KFB96_16455	COG1792	Involved in formation and maintenance of cell shape
KFB96_16465	COG0768	penicillin binding
KFB96_16470	COG0772	Belongs to the SEDS family
KFB96_16475	COG2951	lytic endotransglycosylase activity
KFB96_16595	COG1793	dna ligase
KFB96_16600	COG0579	oxidoreductase
KFB96_16605	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
KFB96_16610	COG0210	DNA helicase
KFB96_16615	COG0539	negative regulation of cytoplasmic translation
KFB96_16620	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
KFB96_16625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFB96_16630	COG0254	rRNA binding
KFB96_16635	COG0039	L-malate dehydrogenase activity
KFB96_16640	COG0372	Belongs to the citrate synthase family
KFB96_16675	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
KFB96_16680	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
KFB96_16685	COG0070	glutamate synthase
KFB96_16685	COG0067	glutamate synthase
KFB96_16685	COG0069	glutamate synthase activity
KFB96_16705	COG1450	Type ii and iii secretion system protein
KFB96_16725	COG3156	type II secretion system protein K
KFB96_16735	COG2165	general secretion pathway protein
KFB96_16740	COG4970	Tfp pilus assembly protein FimT
KFB96_16750	COG1459	type II secretion system
KFB96_16755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KFB96_16765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFB96_16770	COG0693	protein deglycase activity
KFB96_16775	COG0793	Belongs to the peptidase S41A family
KFB96_16780	COG4942	peptidase
KFB96_16790	COG1054	Belongs to the UPF0176 family
KFB96_16795	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
KFB96_16800	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
KFB96_16805	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KFB96_16820	COG2204	response regulator
KFB96_16825	COG3852	Histidine kinase
KFB96_16835	COG0174	glutamine synthetase
KFB96_16840	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
KFB96_16845	COG0752	glycyl-tRNA synthetase alpha subunit
KFB96_16850	COG0751	glycine-tRNA ligase activity
KFB96_16865	COG0187	DNA topoisomerase II activity
KFB96_16870	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFB96_16875	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFB96_16880	COG0592	DNA-directed DNA polymerase activity
KFB96_16885	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
KFB96_16895	COG0594	ribonuclease P activity
KFB96_16900	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
KFB96_16905	COG0706	membrane insertase activity
KFB96_16910	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
KFB96_16945	COG0589	response to stress
KFB96_16950	COG1253	flavin adenine dinucleotide binding
KFB96_16955	COG1253	flavin adenine dinucleotide binding
KFB96_16960	COG1253	flavin adenine dinucleotide binding
KFB96_16965	COG1215	transferase activity, transferring glycosyl groups
KFB96_16980	COG0405	Gamma-glutamyltransferase
KFB96_16985	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KFB96_16990	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
KFB96_16995	COG0742	ribosomal rna small subunit methyltransferase
KFB96_17000	COG0612	Peptidase, M16
KFB96_17005	COG0612	Peptidase, M16
KFB96_17010	COG0552	protein localization to endoplasmic reticulum
KFB96_17015	COG2884	Cell division ATP-binding protein ftsE
KFB96_17020	COG2177	Part of the ABC transporter FtsEX involved in
KFB96_17025	COG0471	metal ion transport
KFB96_17040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KFB96_17075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFB96_17085	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KFB96_17135	COG2914	Belongs to the UPF0125 (RnfH) family
KFB96_17145	COG4659	FMN binding
KFB96_17150	COG4658	electron transport chain
KFB96_17155	COG4656	Part of a membrane complex involved in electron transport
KFB96_17160	COG2878	Part of a membrane complex involved in electron transport
KFB96_17165	COG4657	Part of a membrane complex involved in electron transport
KFB96_17205	COG5001	Diguanylate cyclase
KFB96_17210	COG0517	IMP dehydrogenase activity
KFB96_17210	COG4175	Glycine betaine
KFB96_17240	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KFB96_17245	COG0668	transmembrane transport
KFB96_17250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
KFB96_17300	COG0298	carbon dioxide binding
KFB96_17305	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
KFB96_17310	COG2813	Specifically methylates the guanine in position
KFB96_17335	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KFB96_17355	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
KFB96_17360	COG0004	ammonium transporteR
KFB96_17370	COG0347	Belongs to the P(II) protein family
KFB96_17390	COG0488	(ABC) transporter
KFB96_17395	COG0058	SHG alpha-glucan phosphorylase activity
KFB96_17400	COG0745	RESPONSE REGULATOR receiver
KFB96_17410	COG1366	Belongs to the anti-sigma-factor antagonist family
KFB96_17435	COG3291	Pkd domain containing protein
KFB96_17515	COG0572	uridine kinase
KFB96_17525	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
KFB96_17530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KFB96_17590	COG0633	Ferredoxin
KFB96_17595	COG0426	domain, Protein
KFB96_17615	COG3228	Belongs to the MtfA family
KFB96_17620	COG1999	signal sequence binding
KFB96_17625	COG2847	Copper chaperone PCu(A)C
KFB96_17650	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
KFB96_17655	COG1217	gtp-binding protein TYPA
KFB96_17660	COG0596	Alpha beta hydrolase
KFB96_17665	COG1490	D-aminoacyl-tRNA deacylase activity
KFB96_17680	COG0408	coproporphyrinogen oxidase activity
KFB96_17690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KFB96_17700	COG0194	GDP metabolic process
KFB96_17790	COG3409	Peptidoglycan-binding domain 1 protein
KFB96_17790	COG3267	Type II secretory pathway component ExeA
KFB96_17795	COG3415	Transposase
KFB96_17795	COG2801	Transposase and inactivated derivatives
KFB96_17820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KFB96_17850	COG3119	arylsulfatase activity
KFB96_17870	COG1561	YicC-like family, N-terminal region
KFB96_17875	COG0515	serine threonine protein kinase
KFB96_17875	COG2815	serine threonine protein kinase
KFB96_17880	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
KFB96_17885	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
KFB96_17890	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KFB96_17905	COG1872	DUF167
KFB96_17920	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KFB96_17925	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
KFB96_17935	COG0756	dUTP diphosphatase activity
KFB96_17960	COG4456	Virulence-associated protein
KFB96_17970	COG1192	Involved in chromosome partitioning
KFB96_18010	COG0386	Belongs to the glutathione peroxidase family
KFB96_18040	COG0456	acetyltransferase
KFB96_18185	COG0745	RESPONSE REGULATOR receiver
KFB96_18195	COG0456	acetyltransferase
KFB96_18250	COG3311	Transcriptional regulator
KFB96_18255	COG1569	PIN domain
KFB96_18275	COG1902	pentaerythritol trinitrate reductase activity
KFB96_18315	COG1686	Belongs to the peptidase S11 family
KFB96_18325	COG0321	lipoyl(octanoyl) transferase activity
KFB96_18345	COG0714	Associated with various cellular activities
KFB96_18365	COG3243	poly(R)-hydroxyalkanoic acid synthase
KFB96_18390	COG1028	Short-chain dehydrogenase reductase Sdr
KFB96_18405	COG0151	Belongs to the GarS family
KFB96_18410	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KFB96_18415	COG0138	bifunctional purine biosynthesis protein purh
KFB96_18425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFB96_18435	COG0439	Biotin carboxylase
KFB96_18450	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFB96_18455	COG4232	protein-disulfide reductase activity
KFB96_18460	COG1324	tolerance protein
KFB96_18470	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KFB96_18480	COG3706	GGDEF domain
KFB96_18505	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KFB96_18590	COG0415	Belongs to the DNA photolyase family
KFB96_18600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFB96_18635	COG0676	glucose-6-phosphate 1-epimerase activity
KFB96_18640	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KFB96_18655	COG0418	dihydroorotase activity
KFB96_18660	COG2853	Lipoprotein
KFB96_18670	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFB96_18680	COG0367	asparagine synthase
KFB96_18690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KFB96_18695	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KFB96_18790	COG0830	nickel cation binding
KFB96_18800	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
KFB96_18805	COG0314	molybdopterin synthase activity
KFB96_18825	COG1671	Belongs to the UPF0178 family
KFB96_18835	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
KFB96_18845	COG2022	thiamine diphosphate biosynthetic process
KFB96_18850	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KFB96_18855	COG3842	ATPase activity
KFB96_18860	COG0390	transport system, permease component
KFB96_18865	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
KFB96_18885	COG1166	arginine decarboxylase activity
KFB96_18890	COG0375	protein maturation
KFB96_18900	COG4245	von Willebrand factor, type A
KFB96_18945	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KFB96_18965	COG1358	cellular component organization or biogenesis
KFB96_19000	COG1215	transferase activity, transferring glycosyl groups
KFB96_19005	COG1216	Glycosyl transferase, family 2
KFB96_19040	COG0675	Transposase, IS605 OrfB family
KFB96_19050	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KFB96_19055	COG0154	amidase activity
KFB96_19060	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KFB96_19080	COG0463	Glycosyl transferase, family 2
KFB96_19105	COG0167	dihydroorotate dehydrogenase activity
KFB96_19110	COG0131	Imidazoleglycerol-phosphate dehydratase
KFB96_19115	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
KFB96_19120	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KFB96_19125	COG0140	phosphoribosyl-ATP diphosphatase activity
KFB96_19135	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
KFB96_19145	COG0583	DNA-binding transcription factor activity
KFB96_19170	COG0411	ABC transporter
KFB96_19205	COG1320	monovalent cation:proton antiporter activity
KFB96_19210	COG2212	antiporter activity
KFB96_19215	COG1863	multisubunit Na H antiporter MnhE subunit
KFB96_19220	COG0651	ATP synthesis coupled electron transport
KFB96_19225	COG1006	Multisubunit Na H antiporter MnhC subunit
KFB96_19230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KFB96_19230	COG2111	Na H antiporter
KFB96_19245	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KFB96_19250	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KFB96_19260	COG0513	Belongs to the DEAD box helicase family
KFB96_19275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KFB96_19280	COG0702	epimerase
KFB96_19290	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KFB96_19305	COG1519	Transferase
KFB96_19310	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KFB96_19310	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KFB96_19330	COG0540	Belongs to the ATCase OTCase family
KFB96_19345	COG1678	Uncharacterized ACR, COG1678
KFB96_19355	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KFB96_19365	COG0189	ligase activity
KFB96_19435	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KFB96_19440	COG2363	Small membrane protein
KFB96_19445	COG5433	transposase activity
KFB96_19455	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
KFB96_19470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KFB96_19475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KFB96_19480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
KFB96_19485	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
KFB96_19490	COG1566	PFAM secretion protein HlyD family protein
KFB96_19495	COG1136	(ABC) transporter
KFB96_19495	COG0577	efflux transmembrane transporter activity
KFB96_19500	COG1136	(ABC) transporter
KFB96_19500	COG0577	efflux transmembrane transporter activity
KFB96_19505	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KFB96_19510	COG1028	Short-chain dehydrogenase reductase Sdr
KFB96_19540	COG2226	methyltransferase
KFB96_19545	COG1819	glycosyl
KFB96_19595	COG3119	arylsulfatase activity
KFB96_19600	COG0438	transferase activity, transferring glycosyl groups
KFB96_19600	COG1216	Glycosyl transferase, family 2
KFB96_19650	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KFB96_19660	COG2226	methyltransferase
KFB96_19670	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
KFB96_19680	COG0297	glycogen (starch) synthase activity
KFB96_19690	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
KFB96_19700	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
KFB96_19705	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
KFB96_19710	COG0509	glycine decarboxylation via glycine cleavage system
KFB96_19780	COG0495	leucyl-tRNA aminoacylation
KFB96_19795	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
KFB96_19800	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KFB96_19815	COG0675	Transposase, IS605 OrfB family
KFB96_19830	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KFB96_19835	COG2967	ApaG domain
KFB96_19860	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KFB96_19865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFB96_19870	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
KFB96_19875	COG3178	'Phosphotransferase
KFB96_19880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KFB96_19885	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KFB96_19890	COG0723	plastoquinol--plastocyanin reductase activity
KFB96_19895	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
KFB96_19900	COG2857	Cytochrome c1
KFB96_19905	COG0625	glutathione transferase activity
KFB96_19910	COG2969	positive regulation of protein catabolic process
KFB96_19930	COG0628	permease
KFB96_19985	COG1802	Transcriptional regulator
KFB96_20000	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
KFB96_20005	COG0352	thiamine-phosphate diphosphorylase activity
KFB96_20010	COG0351	phosphomethylpyrimidine kinase
KFB96_20010	COG0352	thiamine-phosphate diphosphorylase activity
KFB96_20015	COG1773	rubredoxin
KFB96_20030	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
KFB96_20040	COG0316	Belongs to the HesB IscA family
KFB96_20045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KFB96_20080	COG0768	penicillin binding
KFB96_20085	COG4948	Mandelate Racemase Muconate Lactonizing
KFB96_20090	COG1575	Belongs to the MenA family. Type 1 subfamily
KFB96_20100	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
KFB96_20115	COG0702	epimerase
KFB96_20140	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KFB96_20180	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
KFB96_20195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KFB96_20200	COG1129	ABC transporter
KFB96_20200	COG0842	Transport permease protein
KFB96_20205	COG0842	Transport permease protein
KFB96_20210	COG0488	(ABC) transporter
KFB96_20300	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
KFB96_20305	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KFB96_20315	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
KFB96_20325	COG1233	COG1233 Phytoene dehydrogenase and related
KFB96_20330	COG1562	ergosterol biosynthetic process
KFB96_20340	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KFB96_20350	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KFB96_20380	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KFB96_20395	COG1477	protein flavinylation
KFB96_20405	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KFB96_20420	COG2255	four-way junction helicase activity
KFB96_20425	COG0277	FAD linked oxidase domain protein
KFB96_20460	COG4974	Belongs to the 'phage' integrase family
KFB96_20465	COG0582	viral genome integration into host DNA
KFB96_20470	COG0582	viral genome integration into host DNA
KFB96_20480	COG3409	Peptidoglycan-binding domain 1 protein
KFB96_20480	COG3267	Type II secretory pathway component ExeA
KFB96_20490	COG0514	ATP-dependent DNA helicase (RecQ)
KFB96_20525	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KFB96_20530	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
KFB96_20545	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KFB96_20575	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KFB96_20595	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KFB96_20615	COG0433	COG0433 Predicted ATPase
KFB96_20630	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
KFB96_20635	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
KFB96_20670	COG0366	Alpha amylase catalytic
KFB96_20675	COG0297	glycogen (starch) synthase activity
KFB96_20680	COG2723	6-phospho-beta-galactosidase activity
KFB96_20685	COG4178	(ABC) transporter
KFB96_20700	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
KFB96_20735	COG0443	Heat shock 70 kDa protein
KFB96_20755	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
KFB96_20765	COG0343	queuine tRNA-ribosyltransferase activity
KFB96_20770	COG1862	Preprotein translocase
KFB96_20775	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFB96_20780	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KFB96_20795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KFB96_20810	COG4181	ATPase activity
KFB96_20835	COG4783	chaperone-mediated protein folding
KFB96_20850	COG1560	Kdo2-lipid A biosynthetic process
KFB96_20900	COG1408	metallophosphoesterase
KFB96_20905	COG2723	6-phospho-beta-galactosidase activity
KFB96_20910	COG1216	Glycosyl transferase, family 2
KFB96_20955	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
KFB96_20965	COG0840	transmembrane signaling receptor activity
KFB96_20975	COG2920	part of a sulfur-relay system
KFB96_20985	COG0071	Belongs to the small heat shock protein (HSP20) family
KFB96_20990	COG3012	SEC-C Motif Domain Protein
KFB96_21000	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KFB96_21010	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
KFB96_21015	COG3259	Nickel-dependent hydrogenase
KFB96_21020	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KFB96_21030	COG1674	ftsk spoiiie
KFB96_21035	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KFB96_21040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KFB96_21055	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KFB96_21060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KFB96_21070	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
KFB96_21085	COG1160	GTP binding
KFB96_21095	COG2976	Protein conserved in bacteria
KFB96_21100	COG0124	histidyl-tRNA synthetase
KFB96_21115	COG0820	rRNA (adenine-C2-)-methyltransferase activity
KFB96_21120	COG0105	UTP biosynthetic process
KFB96_21130	COG0737	Belongs to the 5'-nucleotidase family
KFB96_21155	COG0811	peptide transport
KFB96_21180	COG0280	phosphate acetyltransferase
KFB96_21180	COG0281	malic enzyme
KFB96_21250	COG3409	Peptidoglycan-binding domain 1 protein
KFB96_21250	COG3267	Type II secretory pathway component ExeA
KFB96_21255	COG2801	Transposase and inactivated derivatives
KFB96_21255	COG3415	Transposase
KFB96_21290	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KFB96_21305	COG3447	MASE1 domain protein
KFB96_21305	COG5002	protein histidine kinase activity
KFB96_21305	COG5001	Diguanylate cyclase
KFB96_21325	COG1012	belongs to the aldehyde dehydrogenase family
KFB96_21330	COG2135	peptidase activity
KFB96_21340	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
KFB96_21345	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
KFB96_21365	COG4636	protein conserved in cyanobacteria
KFB96_21395	COG0668	transmembrane transport
KFB96_21410	COG1566	PFAM secretion protein HlyD family protein
KFB96_21445	COG0330	HflC and HflK could
KFB96_21450	COG0330	HflC and HflK could
KFB96_21455	COG0435	Glutathione S-transferase
KFB96_21460	COG4636	protein conserved in cyanobacteria
KFB96_21470	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
KFB96_21475	COG3639	organic phosphonate transmembrane transporter activity
KFB96_21495	COG0583	DNA-binding transcription factor activity
KFB96_21510	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
KFB96_21515	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
KFB96_21540	COG4451	ribulose bisphosphate carboxylase, small
KFB96_21545	COG1850	ribulose-bisphosphate carboxylase activity
KFB96_21550	COG0659	secondary active sulfate transmembrane transporter activity
KFB96_21555	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KFB96_21565	COG0009	L-threonylcarbamoyladenylate synthase
KFB96_21575	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
KFB96_21580	COG1607	acyl-coa hydrolase
KFB96_21605	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KFB96_21650	COG3842	ATPase activity
KFB96_21655	COG1918	ferrous iron import across plasma membrane
KFB96_21655	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
KFB96_21705	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
KFB96_21750	COG4988	ABC transporter
KFB96_21755	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
KFB96_21760	COG4636	protein conserved in cyanobacteria
KFB96_21775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KFB96_21780	COG0438	transferase activity, transferring glycosyl groups
KFB96_21785	COG0693	protein deglycase activity
KFB96_21810	COG0702	epimerase
KFB96_21815	COG1028	Short-chain dehydrogenase reductase Sdr
KFB96_21835	COG2835	tetraacyldisaccharide 4'-kinase activity
KFB96_21880	COG0674	pyruvate-flavodoxin oxidoreductase activity
KFB96_21880	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
KFB96_21885	COG1013	pyruvate-flavodoxin oxidoreductase activity
KFB96_21920	COG3344	reverse transcriptase
KFB96_22075	COG0515	serine threonine protein kinase
KFB96_22075	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KFB96_22085	COG3437	response regulator, receiver
KFB96_22100	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KFB96_22110	COG5002	protein histidine kinase activity
KFB96_22110	COG2205	protein histidine kinase activity
KFB96_22110	COG0784	Response regulator, receiver
KFB96_22120	COG3344	reverse transcriptase
KFB96_22150	COG3119	arylsulfatase activity
KFB96_22170	COG3119	arylsulfatase activity
KFB96_22220	COG3527	Alpha-acetolactate decarboxylase
KFB96_22255	COG4771	TonB-dependent receptor
KFB96_22300	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
KFB96_22305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
KFB96_22330	COG3267	Type II secretory pathway component ExeA
KFB96_22330	COG3409	Peptidoglycan-binding domain 1 protein
KFB96_22340	COG2239	Acts as a magnesium transporter
KFB96_22375	COG0640	Transcriptional regulator
KFB96_22385	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KFB96_22400	COG1752	Esterase of the alpha-beta hydrolase superfamily
KFB96_22420	COG3264	Mechanosensitive ion channel
KFB96_22420	COG1511	domain protein
KFB96_22440	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KFB96_22450	COG0456	acetyltransferase
KFB96_22455	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KFB96_22465	COG2308	Evidence 4 Homologs of previously reported genes of
KFB96_22465	COG2307	Protein conserved in bacteria
KFB96_22475	COG0318	PFAM AMP-dependent synthetase and ligase
KFB96_22490	COG1355	regulation of microtubule-based process
KFB96_22565	COG3706	GGDEF domain
KFB96_22590	COG0443	Heat shock 70 kDa protein
KFB96_22610	COG2095	MarC family integral membrane protein
KFB96_22645	COG4206	TonB-dependent receptor
KFB96_22665	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KFB96_22675	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
KFB96_22700	COG0745	RESPONSE REGULATOR receiver
KFB96_22705	COG5002	protein histidine kinase activity
KFB96_22715	COG5002	protein histidine kinase activity
KFB96_22715	COG2205	protein histidine kinase activity
KFB96_22715	COG0784	Response regulator, receiver
KFB96_22725	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
KFB96_22740	COG0058	SHG alpha-glucan phosphorylase activity
KFB96_22750	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
KFB96_22760	COG0363	glucosamine-6-phosphate deaminase activity
KFB96_22765	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KFB96_22785	COG1487	ribonuclease activity
KFB96_22820	COG2957	Belongs to the agmatine deiminase family
KFB96_22830	COG4566	intracellular signal transduction
KFB96_22855	COG4591	ABC-type transport system involved in lipoprotein release permease component
KFB96_22860	COG1136	(ABC) transporter
KFB96_22870	COG0658	competence protein
KFB96_22870	COG2333	competence protein COMEC
KFB96_22875	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KFB96_22885	COG1214	PFAM Peptidase M22, glycoprotease
KFB96_22900	COG2833	Protein of unknown function (DUF455)
KFB96_22910	COG2862	Uncharacterized protein family, UPF0114
KFB96_22960	COG1131	(ABC) transporter
KFB96_22995	COG0500	methyltransferase
KFB96_23000	COG0267	Belongs to the bacterial ribosomal protein bL33 family
KFB96_23005	COG0227	Belongs to the bacterial ribosomal protein bL28 family
KFB96_23025	COG0577	efflux transmembrane transporter activity
KFB96_23025	COG1136	(ABC) transporter
KFB96_23030	COG1136	(ABC) transporter
KFB96_23030	COG0577	efflux transmembrane transporter activity
KFB96_23050	COG1269	ATP hydrolysis coupled proton transport
KFB96_23070	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
KFB96_23080	COG1136	(ABC) transporter
KFB96_23105	COG2304	oxidoreductase activity
KFB96_23125	COG0714	Associated with various cellular activities
KFB96_23155	COG0700	Nucleoside recognition
KFB96_23175	COG0439	Biotin carboxylase
KFB96_23185	COG5016	pyruvate
KFB96_23185	COG0511	ligase activity, forming carbon-carbon bonds
KFB96_23195	COG0477	Major facilitator Superfamily
KFB96_23220	COG2119	membrane
KFB96_23230	COG3443	Belongs to the bacterial solute-binding protein 9 family
KFB96_23230	COG0803	Belongs to the bacterial solute-binding protein 9 family
KFB96_23240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KFB96_23245	COG0735	belongs to the Fur family
KFB96_23270	COG4181	ATPase activity
KFB96_23280	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KFB96_23285	COG1074	ATP-dependent DNA helicase activity
KFB96_23290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KFB96_23315	COG2373	Large extracellular alpha-helical protein
KFB96_23325	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KFB96_23325	COG0574	Belongs to the PEP-utilizing enzyme family
KFB96_23335	COG2205	protein histidine kinase activity
KFB96_23345	COG2204	response regulator
KFB96_23360	COG0189	ligase activity
KFB96_23365	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
KFB96_23370	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KFB96_23375	COG0196	riboflavin kinase activity
KFB96_23380	COG0728	peptidoglycan biosynthetic process
KFB96_23390	COG0268	Binds directly to 16S ribosomal RNA
KFB96_23395	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
KFB96_23405	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KFB96_23410	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KFB96_23425	COG3278	Belongs to the heme-copper respiratory oxidase family
KFB96_23460	COG2217	Heavy metal translocating P-type atpase
KFB96_23475	COG0033	Phosphoglucomutase
KFB96_23480	COG0326	Molecular chaperone. Has ATPase activity
KFB96_23485	COG0563	adenylate kinase activity
KFB96_23490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KFB96_23500	COG1959	2 iron, 2 sulfur cluster binding
KFB96_23505	COG2890	protein-(glutamine-N5) methyltransferase activity
KFB96_23525	COG0544	peptidyl-prolyl cis-trans isomerase activity
KFB96_23530	COG0740	serine-type endopeptidase activity
KFB96_23535	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
KFB96_23540	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
KFB96_23560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFB96_23575	COG0601	transmembrane transport
KFB96_23580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KFB96_23595	COG1278	Cold shock
KFB96_23610	COG3034	peptidoglycan biosynthetic process
KFB96_23620	COG1388	LysM domain
KFB96_23620	COG0741	lytic transglycosylase activity
KFB96_23630	COG0328	RNA-DNA hybrid ribonuclease activity
KFB96_23635	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KFB96_23640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KFB96_23645	COG0504	CTP synthase activity
KFB96_23650	COG2877	3-deoxy-8-phosphooctulonate synthase activity
KFB96_23655	COG0148	phosphopyruvate hydratase activity
KFB96_23660	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KFB96_23665	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
KFB96_23670	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
KFB96_23675	COG0585	pseudouridine synthase activity
KFB96_23680	COG3174	membrane
KFB96_23710	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KFB96_23715	COG0076	glutamate decarboxylase activity
KFB96_23740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KFB96_23745	COG0815	Transfers the fatty acyl group on membrane lipoproteins
KFB96_23755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KFB96_23780	COG0567	Dehydrogenase, E1 component
KFB96_23805	COG5002	protein histidine kinase activity
KFB96_23805	COG2205	protein histidine kinase activity
KFB96_23805	COG0784	Response regulator, receiver
KFB96_23820	COG4771	TonB-dependent receptor
KFB96_23830	COG0543	2 iron, 2 sulfur cluster binding
KFB96_23830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KFB96_23855	COG0724	RNA recognition motif
KFB96_23860	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
KFB96_23865	COG0339	signal peptide processing
KFB96_23880	COG1196	nuclear chromosome segregation
KFB96_23890	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
KFB96_23915	COG3005	denitrification pathway
KFB96_23925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KFB96_23930	COG2350	Protein conserved in bacteria
KFB96_23935	COG2917	probably involved in intracellular septation
KFB96_23970	COG0271	Belongs to the BolA IbaG family
KFB96_23980	COG0569	domain protein
KFB96_23985	COG2204	response regulator
KFB96_23990	COG5000	phosphorelay sensor kinase activity
KFB96_24010	COG0242	peptide deformylase activity
KFB96_24020	COG0758	DNA mediated transformation
KFB96_24025	COG2922	Belongs to the Smg family
KFB96_24040	COG0701	Predicted permease
KFB96_24055	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
KFB96_24065	COG2951	lytic endotransglycosylase activity
KFB96_24070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KFB96_24085	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KFB96_24090	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
KFB96_24095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KFB96_24100	COG0250	Participates in transcription elongation, termination and antitermination
KFB96_24110	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
KFB96_24120	COG0517	IMP dehydrogenase activity
KFB96_24120	COG0516	GMP reductase activity
KFB96_24150	COG5265	(ABC) transporter
KFB96_24155	COG3850	Histidine kinase
KFB96_24160	COG2197	response regulator
KFB96_24165	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
KFB96_24185	COG0215	cysteine-tRNA ligase activity
KFB96_24225	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KFB96_24230	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
KFB96_24235	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KFB96_24240	COG0537	adenosine 5'-monophosphoramidase activity
KFB96_24245	COG0850	regulation of cytokinetic process
KFB96_24250	COG2894	cell division
KFB96_24255	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
KFB96_24265	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
KFB96_24270	COG1331	Highly conserved protein containing a thioredoxin domain
KFB96_24285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
KFB96_24295	COG0824	Thioesterase
KFB96_24315	COG0823	Involved in the tonB-independent uptake of proteins
KFB96_24320	COG2885	chlorophyll binding
KFB96_24335	COG0582	viral genome integration into host DNA
KFB96_24380	COG0583	DNA-binding transcription factor activity
KFB96_24450	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KFB96_24460	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KFB96_24620	COG3077	Addiction module antitoxin, RelB DinJ family
KFB96_24640	COG2337	Toxic component of a toxin-antitoxin (TA) module
KFB96_24665	COG3344	reverse transcriptase
KFB96_24685	COG0297	glycogen (starch) synthase activity
KFB96_24700	COG0297	glycogen (starch) synthase activity
KFB96_24710	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KFB96_24715	COG0297	glycogen (starch) synthase activity
KFB96_24735	COG1598	PFAM Uncharacterised protein family UPF0150
KFB96_24830	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KFB96_24855	COG4464	protein tyrosine phosphatase activity
KFB96_24945	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KFB96_24960	COG4636	protein conserved in cyanobacteria
KFB96_25000	COG1201	RNA secondary structure unwinding
KFB96_25040	COG1484	DNA-dependent DNA replication
KFB96_25065	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
KFB96_25070	COG0149	triose-phosphate isomerase activity
KFB96_25085	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFB96_25090	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFB96_25095	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFB96_25100	COG0649	NAD binding
KFB96_25120	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
KFB96_25125	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KFB96_25135	COG0713	ATP synthesis coupled electron transport
KFB96_25150	COG1007	ATP synthesis coupled electron transport
KFB96_25155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KFB96_25160	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
KFB96_25165	COG0321	lipoyl(octanoyl) transferase activity
KFB96_25165	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
KFB96_25170	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KFB96_25205	COG3657	addiction module killer protein
KFB96_25210	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KFB96_25220	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
KFB96_25240	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KFB96_25255	COG1394	ATPase activity, coupled to movement of substances
KFB96_25290	COG1469	GTP cyclohydrolase I activity
KFB96_25295	COG0142	geranyltranstransferase activity
KFB96_25370	COG3706	GGDEF domain
KFB96_25400	COG3737	Protein of unknown function (DUF498/DUF598)
KFB96_25405	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KFB96_25410	COG0297	glycogen (starch) synthase activity
KFB96_25415	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KFB96_25430	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KFB96_25435	COG0720	synthase
KFB96_25440	COG0602	queuosine metabolic process
KFB96_25460	COG0784	Response regulator, receiver
KFB96_25460	COG2205	protein histidine kinase activity
KFB96_25460	COG5002	protein histidine kinase activity
KFB96_25470	COG0270	DNA (cytosine-5-)-methyltransferase activity
KFB96_25475	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
KFB96_25480	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
KFB96_25485	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
KFB96_25520	COG0310	cobalt ion transport
KFB96_25525	COG0310	cobalt ion transport
KFB96_25550	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
KFB96_25555	COG0644	oxidoreductase
KFB96_25595	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
KFB96_25605	COG0521	Mo-molybdopterin cofactor biosynthetic process
KFB96_25620	COG3093	addiction module antidote protein HigA
KFB96_25640	COG0322	excinuclease ABC activity
KFB96_25725	COG0210	DNA helicase
KFB96_25735	COG3118	belongs to the thioredoxin family
KFB96_25760	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KFB96_25780	COG0437	4 iron, 4 sulfur cluster binding
KFB96_25785	COG0243	molybdopterin cofactor binding
KFB96_25805	COG4191	Histidine kinase
KFB96_25830	COG0798	PFAM Bile acid sodium symporter
KFB96_25835	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
KFB96_25855	COG0659	secondary active sulfate transmembrane transporter activity
KFB96_25890	COG1151	hydroxylamine reductase activity
KFB96_25920	COG0613	PHP domain protein
KFB96_25925	COG0009	L-threonylcarbamoyladenylate synthase
KFB96_25930	COG1994	Peptidase M50
KFB96_25935	COG0180	Tryptophanyl-tRNA synthetase
KFB96_25940	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KFB96_25945	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KFB96_25950	COG1187	pseudouridine synthase activity
KFB96_25955	COG5642	Protein of unknown function (DUF2384)
KFB96_25960	COG5654	RES domain protein
KFB96_25965	COG0531	amino acid
KFB96_26005	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
KFB96_26025	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KFB96_26090	COG4453	Protein conserved in bacteria
KFB96_26130	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KFB96_26140	COG0617	tRNA 3'-terminal CCA addition
KFB96_26145	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
KFB96_26155	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
KFB96_26160	COG0297	glycogen (starch) synthase activity
KFB96_26165	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
KFB96_26170	COG0166	Belongs to the GPI family
KFB96_26175	COG2766	serine protein kinase
KFB96_26180	COG2718	Belongs to the UPF0229 family
KFB96_26185	COG2719	SpoVR family
KFB96_26190	COG2989	Protein conserved in bacteria
KFB96_26195	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides