locus-tag	class	description
FOKN1_0010	ENOG41066VF	YeeE YedE family protein
FOKN1_0011	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
FOKN1_0012	ENOG4105D3R	alkyl hydroperoxide reductase
FOKN1_0019	ENOG4105C59	p-type ATPase
FOKN1_0021	ENOG4105C58	cytochrome c oxidase accessory protein ccog
FOKN1_0022	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
FOKN1_0025	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
FOKN1_0026	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
FOKN1_0032	ENOG4105BZ9	Cytochrome C oxidase, subunit I
FOKN1_0033	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
FOKN1_0036	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
FOKN1_0037	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
FOKN1_0038	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FOKN1_0039	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
FOKN1_0041	ENOG4105MJ2	Competence protein
FOKN1_0045	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
FOKN1_0046	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
FOKN1_0047	ENOG4105CB5	ATP-dependent DNA helicase recG
FOKN1_0048	ENOG4105KME	endoribonuclease L-psp
FOKN1_0049	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FOKN1_0050	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
FOKN1_0051	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FOKN1_0052	ENOG4105DSJ	YicC domain protein
FOKN1_0054	ENOG4108ZF3	Phosphatase
FOKN1_0055	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
FOKN1_0056	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FOKN1_0057	ENOG4105CSA	Coproporphyrinogen iii oxidase
FOKN1_0060	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
FOKN1_0062	ENOG4105VFB	Binds the 23S rRNA (By similarity)
FOKN1_0065	ENOG4105C6K	Malic enzyme
FOKN1_0067	ENOG4108JQC	penicillin-binding protein 1A
FOKN1_0072	ENOG4105E4G	Type IV pilus
FOKN1_0073	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
FOKN1_0074	ENOG4105D49	3-dehydroquinate synthase
FOKN1_0075	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
FOKN1_0080	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
FOKN1_0081	ENOG4105BZU	Histidine kinase
FOKN1_0085	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FOKN1_0086	ENOG4105W8H	transhydrogenase (subunit alpha
FOKN1_0087	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FOKN1_0088	ENOG4105HDD	phospholipase
FOKN1_0089	ENOG4105C25	Primosomal protein n'
FOKN1_0090	ENOG4105C75	arginyL-tRNA synthetase
FOKN1_0092	ENOG4105CHB	tonB-dependent Receptor
FOKN1_0095	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
FOKN1_0096	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
FOKN1_0097	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
FOKN1_0099	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FOKN1_0100	ENOG4105CH5	extracellular solute-binding protein, family 7
FOKN1_0101	ENOG4105BZU	Histidine kinase
FOKN1_0103	ENOG4105C4R	Atp-dependent dna helicase
FOKN1_0106	ENOG4105CMI	transporter
FOKN1_0107	ENOG4105CJ1	ABC, transporter
FOKN1_0108	ENOG4105D0S	secretion protein (HlyD
FOKN1_0109	ENOG4105CMM	transposase
FOKN1_0112	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
FOKN1_0113	ENOG41080VW	acetyltransferase
FOKN1_0114	ENOG4105CBC	glutamate synthase
FOKN1_0115	ENOG4105KAV	tspo and mbr like protein
FOKN1_0116	ENOG4105NXH	GreA GreB family elongation factor
FOKN1_0119	ENOG4108UPT	UPF0178 protein
FOKN1_0123	ENOG4105DJ9	glucan biosynthesis protein
FOKN1_0125	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
FOKN1_0127	ENOG4105VAV	hemerythrin-like, metal-binding protein
FOKN1_0129	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
FOKN1_0130	ENOG4105K4H	Nlp p60 protein
FOKN1_0131	ENOG4108IJ8	ABC transporter
FOKN1_0134	ENOG4105CD5	CoA-binding domain protein
FOKN1_0137	ENOG4107SJW	iron permease, FTR1
FOKN1_0139	ENOG4108EX3	reductase
FOKN1_0142	ENOG4108YY7	Invasion gene expression up-regulator SirB
FOKN1_0143	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FOKN1_0145	ENOG4105MQ2	17 kDa surface antigen
FOKN1_0149	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FOKN1_0153	ENOG4105NI8	Cytosine-specific methyltransferase
FOKN1_0158	ENOG4105MPD	Cytochrome
FOKN1_0160	ENOG4105C4R	Atp-dependent dna helicase
FOKN1_0163	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
FOKN1_0164	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
FOKN1_0171	ENOG4107QHF	type ii secretion system protein e
FOKN1_0172	ENOG4105D7Q	type ii secretion system
FOKN1_0179	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FOKN1_0180	ENOG4105CUX	Signal transduction histidine kinase
FOKN1_0182	ENOG4105C5F	glutamine synthetase
FOKN1_0185	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FOKN1_0188	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
FOKN1_0189	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
FOKN1_0191	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
FOKN1_0193	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FOKN1_0194	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FOKN1_0195	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FOKN1_0196	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FOKN1_0197	ENOG4105VG0	50S ribosomal protein l34
FOKN1_0198	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
FOKN1_0199	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
FOKN1_0200	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FOKN1_0201	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FOKN1_0202	ENOG4105DFP	Integrase
FOKN1_0207	ENOG4105CVR	type I restriction-modification system
FOKN1_0214	ENOG4108YZY	peptidylprolyl cis-trans isomerase
FOKN1_0215	ENOG4105F8C	transglutaminase domain-containing protein
FOKN1_0217	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FOKN1_0219	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
FOKN1_0220	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
FOKN1_0221	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
FOKN1_0222	ENOG4107QJE	Chromosome Partitioning Protein
FOKN1_0223	ENOG4105FA0	parb-like partition protein
FOKN1_0225	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
FOKN1_0226	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FOKN1_0227	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FOKN1_0228	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FOKN1_0229	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FOKN1_0230	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
FOKN1_0231	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FOKN1_0232	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FOKN1_0233	ENOG4108YZY	peptidylprolyl cis-trans isomerase
FOKN1_0234	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
FOKN1_0235	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FOKN1_0236	ENOG4105CVR	type I restriction-modification system
FOKN1_0247	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FOKN1_0253	ENOG41067TZ	transcriptional regulator, MarR family
FOKN1_0255	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
FOKN1_0256	ENOG4105D7K	pfkb domain protein
FOKN1_0257	ENOG4105Q84	sucrose synthase
FOKN1_0258	ENOG4105Q84	sucrose synthase
FOKN1_0263	ENOG4105C5H	ABC transporter
FOKN1_0264	ENOG4108Z0R	Transferase
FOKN1_0266	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
FOKN1_0269	ENOG4105E2X	shikimate dehydrogenase
FOKN1_0270	ENOG4105D52	delta-aminolevulinic acid dehydratase
FOKN1_0273	ENOG4105VCQ	rubredoxin
FOKN1_0274	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
FOKN1_0275	ENOG4105BZU	Histidine kinase
FOKN1_0276	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FOKN1_0279	ENOG4108YZA	Nitrogen regulatory protein pii
FOKN1_0280	ENOG4105W0Z	cytoplasmic protein
FOKN1_0281	ENOG4105C0P	Mg chelatase subunit ChlI
FOKN1_0283	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FOKN1_0284	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
FOKN1_0285	ENOG4105VW4	glutaredoxin 3
FOKN1_0286	ENOG41085GJ	domain protein
FOKN1_0287	ENOG41080HT	Transcriptional regulator, arsr family
FOKN1_0289	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FOKN1_0290	ENOG41063SB	peptidase
FOKN1_0291	ENOG4105CN1	protease
FOKN1_0292	ENOG4105PXI	polysaccharide deacetylase
FOKN1_0293	ENOG4107S0N	DJ-1 family
FOKN1_0294	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
FOKN1_0300	ENOG4105CVI	Transcriptional regulator
FOKN1_0302	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
FOKN1_0303	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
FOKN1_0304	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FOKN1_0306	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
FOKN1_0307	ENOG4105BZU	Histidine kinase
FOKN1_0308	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
FOKN1_0313	ENOG4108UK5	Transposase
FOKN1_0316	ENOG4107T0K	Adenylate cyclase
FOKN1_0320	ENOG4105BZU	Histidine kinase
FOKN1_0321	ENOG4105CH7	arginosuccinase
FOKN1_0323	ENOG4108NEV	two component transcriptional regulator, LytTR family
FOKN1_0325	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FOKN1_0326	ENOG41076E6	Uroporphyrinogen-III Synthase
FOKN1_0329	ENOG4108EX3	reductase
FOKN1_0331	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
FOKN1_0332	ENOG4105DGW	oligopeptidase A
FOKN1_0336	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
FOKN1_0338	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
FOKN1_0340	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
FOKN1_0342	ENOG4105K78	MarR family Transcriptional regulator
FOKN1_0347	ENOG4105WAP	TPR repeat-containing protein
FOKN1_0348	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
FOKN1_0349	ENOG4105C1A	potassium transporter peripheral membrane
FOKN1_0350	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FOKN1_0351	ENOG4105ES5	Histidine kinase
FOKN1_0353	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FOKN1_0354	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FOKN1_0355	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FOKN1_0357	ENOG4105C79	DNA protecting protein DprA
FOKN1_0358	ENOG4108RPN	Protein smg homolog
FOKN1_0360	ENOG4105BZU	Histidine kinase
FOKN1_0361	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FOKN1_0365	ENOG4105C2M	dna polymerase I
FOKN1_0366	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
FOKN1_0368	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
FOKN1_0369	ENOG4105CRE	cytochrome C
FOKN1_0371	ENOG4105C7K	acetolactate synthase
FOKN1_0373	ENOG4105BZU	Histidine kinase
FOKN1_0374	ENOG4105CHF	Glutathione S-transferase
FOKN1_0378	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
FOKN1_0379	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FOKN1_0380	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
FOKN1_0381	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
FOKN1_0382	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
FOKN1_0383	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
FOKN1_0384	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
FOKN1_0385	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
FOKN1_0387	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
FOKN1_0390	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
FOKN1_0394	ENOG4105E3A	(ABC) transporter
FOKN1_0395	ENOG4105DA5	(ABC) transporter
FOKN1_0397	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
FOKN1_0401	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
FOKN1_0402	ENOG4108VYJ	response regulator receiver protein
FOKN1_0404	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
FOKN1_0406	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FOKN1_0411	ENOG4105BZU	Histidine kinase
FOKN1_0414	ENOG41082IR	Excinuclease ABC C subunit domain protein
FOKN1_0419	ENOG4105VEQ	Cold shock protein
FOKN1_0423	ENOG4105C3R	Methionine synthase
FOKN1_0426	ENOG4105DH4	Periplasmic copper-binding protein
FOKN1_0427	ENOG4105CIG	ABC transporter
FOKN1_0428	ENOG4108T0W	nitrous oxide maturation protein NosY
FOKN1_0431	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
FOKN1_0435	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FOKN1_0436	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FOKN1_0437	ENOG4105KTH	gatB Yqey
FOKN1_0438	ENOG4105VCC	30S ribosomal protein S21
FOKN1_0439	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FOKN1_0440	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
FOKN1_0444	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FOKN1_0446	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FOKN1_0448	ENOG4107R4Z	monovalent cation h antiporter subunit d
FOKN1_0449	ENOG4108JPZ	Monovalent cation H antiporter subunit D
FOKN1_0450	ENOG4108JPZ	Monovalent cation H antiporter subunit D
FOKN1_0453	ENOG4105KJM	monovalent cation h antiporter subunit g
FOKN1_0456	ENOG4105E4C	Lytic transglycosylase catalytic
FOKN1_0457	ENOG4105C26	Dehydrogenase
FOKN1_0458	ENOG4105HF0	Membrane
FOKN1_0459	ENOG4105F64	nitrite reductase
FOKN1_0460	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FOKN1_0461	ENOG4105Y7H	Cytochrome
FOKN1_0462	ENOG4106P6N	cytochrome d1 heme region
FOKN1_0463	ENOG4108ZGY	Transcriptional regulator (AsnC family)
FOKN1_0466	ENOG4108UMR	transcriptional regulator AsnC family
FOKN1_0471	ENOG4108VKQ	nitriC oxide reductase
FOKN1_0472	ENOG4105DSQ	Nitric oxide reductase
FOKN1_0475	ENOG4105GMT	ATPase associated with various cellular activities aaa_5
FOKN1_0480	ENOG4105N5T	Radical SAM Protein
FOKN1_0481	ENOG4105CFP	Peptidase U32
FOKN1_0482	ENOG4106RZ4	Peptidase U32
FOKN1_0486	ENOG4105XPQ	lipid carrier protein
FOKN1_0487	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
FOKN1_0488	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
FOKN1_0489	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FOKN1_0490	ENOG4108KDI	dmso reductase anchor subunit
FOKN1_0491	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FOKN1_0492	ENOG4105DB1	molybdopterin oxidoreductase
FOKN1_0493	ENOG4105CVA	phosphate
FOKN1_0494	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
FOKN1_0497	ENOG4105FAE	von Willebrand factor, type A
FOKN1_0498	ENOG4107Y49	methyltransferase
FOKN1_0499	ENOG4105BZU	Histidine kinase
FOKN1_0500	ENOG4105DUM	transcriptional regulator, lysR family
FOKN1_0503	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
FOKN1_0504	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FOKN1_0505	ENOG4105C8V	SAICAR synthetase
FOKN1_0509	ENOG4108IJF	Heavy metal efflux pump, CzcA
FOKN1_0516	ENOG4107RT3	EamA-like transporter family
FOKN1_0520	ENOG4105PGM	cation diffusion facilitator family transporter
FOKN1_0521	ENOG4105E3B	Multicopper oxidase
FOKN1_0526	ENOG4105CJW	magnesium transporter
FOKN1_0528	ENOG4108RPX	mosc domain containing protein
FOKN1_0529	ENOG4105C59	p-type ATPase
FOKN1_0538	ENOG4105BZU	Histidine kinase
FOKN1_0539	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FOKN1_0546	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
FOKN1_0548	ENOG4105CPC	Aldo Keto reductase
FOKN1_0550	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
FOKN1_0551	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
FOKN1_0552	ENOG4105EGS	Mechanosensitive ion channel
FOKN1_0553	ENOG4105D7N	magnesium and cobalt transport protein CorA
FOKN1_0554	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
FOKN1_0556	ENOG4108IQE	Amp-dependent synthetase and ligase
FOKN1_0562	ENOG4107QHF	type ii secretion system protein e
FOKN1_0564	ENOG4108GAE	asmA family
FOKN1_0565	ENOG4105CEN	a g-specific adenine glycosylase
FOKN1_0566	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
FOKN1_0573	ENOG4107RIQ	Sulfate adenylate transferase
FOKN1_0585	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
FOKN1_0587	ENOG4106WTF	Glycosyl transferase, family 2
FOKN1_0588	ENOG4106CD9	glycosyl transferase group 1
FOKN1_0590	ENOG4105ESV	Glycosyl transferase, family 4
FOKN1_0595	ENOG4105BZU	Histidine kinase
FOKN1_0596	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FOKN1_0597	ENOG41082IR	Excinuclease ABC C subunit domain protein
FOKN1_0598	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
FOKN1_0599	ENOG4105VF7	tolerance protein
FOKN1_0601	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FOKN1_0602	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FOKN1_0604	ENOG4105EMN	RNA polymerase sigma factor
FOKN1_0605	ENOG4105CZX	twitching motility protein
FOKN1_0606	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
FOKN1_0607	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FOKN1_0616	ENOG4105D1S	lipid A biosynthesis
FOKN1_0617	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
FOKN1_0619	ENOG4105DFG	type I secretion outer membrane protein
FOKN1_0620	ENOG41082J7	Rhodanese domain protein
FOKN1_0621	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
FOKN1_0624	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
FOKN1_0627	ENOG4107QJE	Chromosome Partitioning Protein
FOKN1_0630	ENOG4105NXH	GreA GreB family elongation factor
FOKN1_0632	ENOG4107YHV	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FOKN1_0639	ENOG4105VFE	sira family
FOKN1_0642	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
FOKN1_0644	ENOG4105C09	Bile acid
FOKN1_0648	ENOG4107SDU	Methyl-accepting chemotaxis
FOKN1_0652	ENOG4105BZU	Histidine kinase
FOKN1_0653	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
FOKN1_0659	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
FOKN1_0660	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FOKN1_0664	ENOG4105MPD	Cytochrome
FOKN1_0665	ENOG4105D7A	ATP-binding protein
FOKN1_0673	ENOG4105BZU	Histidine kinase
FOKN1_0674	ENOG4105BZU	Histidine kinase
FOKN1_0688	ENOG4108IJ7	Glycine betaine
FOKN1_0689	ENOG4108HQS	Glycine betaine
FOKN1_0694	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FOKN1_0697	ENOG4105C7K	acetolactate synthase
FOKN1_0698	ENOG4105D0C	transport protein
FOKN1_0701	ENOG4105BZS	acriflavin resistance protein
FOKN1_0702	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FOKN1_0706	ENOG4105C1J	atp-dependent rna helicase
FOKN1_0708	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
FOKN1_0709	ENOG4108VFZ	ribulose bisphosphate carboxylase, small
FOKN1_0713	ENOG4105WVM	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FOKN1_0714	ENOG4105KNY	Microcompartments protein
FOKN1_0715	ENOG4108WT6	Carbon dioxide concentrating mechanism protein
FOKN1_0716	ENOG4105KNY	Microcompartments protein
FOKN1_0717	ENOG4108UQY	Iron-storage protein
FOKN1_0721	ENOG4105CHH	sulfate transporter
FOKN1_0722	ENOG4105DUM	transcriptional regulator, lysR family
FOKN1_0725	ENOG410692J	cytochrome C, class I
FOKN1_0726	ENOG4107S7U	Sulfide dehydrogenase
FOKN1_0727	ENOG4105WS7	Cation transport regulator
FOKN1_0728	ENOG4105WKW	Pfam:DUF1458
FOKN1_0729	ENOG4105N1F	Hnh endonuclease
FOKN1_0731	ENOG4105C5H	ABC transporter
FOKN1_0736	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
FOKN1_0738	ENOG4105I08	Pseudouridine synthase
FOKN1_0740	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
FOKN1_0741	ENOG4105CVG	Homoserine O-transsuccinylase
FOKN1_0747	ENOG4108HU6	Metal dependent phosphohydrolase
FOKN1_0753	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FOKN1_0754	ENOG4105M00	molybdopterin converting factor, subunit 1
FOKN1_0755	ENOG4108ZAF	Molybdopterin
FOKN1_0756	ENOG4105F0N	pyrophosphate phospho-hydrolase
FOKN1_0757	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FOKN1_0758	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
FOKN1_0759	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FOKN1_0760	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
FOKN1_0762	ENOG4105DFU	Cell wall formation (By similarity)
FOKN1_0763	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
FOKN1_0765	ENOG4108KF1	Membrane
FOKN1_0766	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
FOKN1_0767	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FOKN1_0770	ENOG4108VAU	general secretion pathway protein G
FOKN1_0773	ENOG4108WWZ	General secretion pathway protein J
FOKN1_0774	ENOG4108RTD	type II secretion system protein K
FOKN1_0775	ENOG4108ADH	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
FOKN1_0779	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
FOKN1_0780	ENOG4107RK2	ADP-ribose diphosphatase NudE
FOKN1_0781	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
FOKN1_0784	ENOG4108QV3	biosynthesis protein
FOKN1_0791	ENOG4107RDJ	Sulfotransferase
FOKN1_0792	ENOG4107RBS	Methyltransferase
FOKN1_0795	ENOG4107RDJ	Sulfotransferase
FOKN1_0797	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
FOKN1_0798	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
FOKN1_0799	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
FOKN1_0801	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FOKN1_0802	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FOKN1_0804	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FOKN1_0805	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
FOKN1_0806	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FOKN1_0807	ENOG4105C12	Phosphoribosylglycinamide synthetase
FOKN1_0808	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
FOKN1_0809	ENOG4105K63	Thioredoxin
FOKN1_0810	ENOG4105C1J	atp-dependent rna helicase
FOKN1_0812	ENOG4105GVR	general secretion pathway protein D
FOKN1_0813	ENOG4107QHF	type ii secretion system protein e
FOKN1_0814	ENOG4105D7Q	type ii secretion system
FOKN1_0817	ENOG4105C9Q	fumarate hydratase class II
FOKN1_0818	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
FOKN1_0819	ENOG4107QZM	n-acetylglutamate synthase
FOKN1_0820	ENOG4105CWC	Acetylornithine deacetylase
FOKN1_0821	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
FOKN1_0822	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FOKN1_0823	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
FOKN1_0824	ENOG4105C01	Dihydroxy-acid dehydratase
FOKN1_0827	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
FOKN1_0828	ENOG4105CVJ	phosphoglycerate mutase
FOKN1_0830	ENOG4105CGK	Exodeoxyribonuclease III
FOKN1_0836	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
FOKN1_0838	ENOG4105C5I	Dehydrogenase
FOKN1_0839	ENOG4108NVR	Methyl-accepting chemotaxis
FOKN1_0840	ENOG4108UYB	regulatoR
FOKN1_0841	ENOG4105BZU	Histidine kinase
FOKN1_0842	ENOG4105CHB	tonB-dependent Receptor
FOKN1_0846	ENOG4108YZ4	nudix hydrolase
FOKN1_0848	ENOG4105IH7	synthase
FOKN1_0849	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
FOKN1_0851	ENOG4107VUZ	
FOKN1_0852	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FOKN1_0854	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FOKN1_0855	ENOG4105D6Z	AFG1 family ATPase
FOKN1_0861	ENOG4105ECY	inositol monophosphatase
FOKN1_0863	ENOG4105CNG	UPF0061 protein
FOKN1_0865	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
FOKN1_0866	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FOKN1_0867	ENOG4108YZY	peptidylprolyl cis-trans isomerase
FOKN1_0868	ENOG4105E0X	reductase
FOKN1_0873	ENOG4107QK7	reductase
FOKN1_0876	ENOG4105CCT	upf0313 protein
FOKN1_0878	ENOG41085GJ	domain protein
FOKN1_0882	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FOKN1_0888	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
FOKN1_0889	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
FOKN1_0890	ENOG4105KPV	Transcriptional regulator
FOKN1_0892	ENOG4105KHC	sulfurtransferase
FOKN1_0894	ENOG4108V0P	LemA family
FOKN1_0896	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
FOKN1_0897	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FOKN1_0899	ENOG4105EAH	synthase
FOKN1_0900	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FOKN1_0902	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOKN1_0903	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
FOKN1_0904	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
FOKN1_0905	ENOG4105CJR	Integral membrane protein (MviN
FOKN1_0906	ENOG4105DTN	riboflavin biosynthesis protein ribF
FOKN1_0907	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FOKN1_0908	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
FOKN1_0910	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
FOKN1_0911	ENOG4108ZUW	Major pilin subunit
FOKN1_0923	ENOG4108DN8	FAD dependent oxidoreductase
FOKN1_0924	ENOG41090R7	Ferric uptake
FOKN1_0927	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
FOKN1_0929	ENOG4105CXT	aspartate transcarbamylase
FOKN1_0930	ENOG4105CAQ	asparagine synthetase
FOKN1_0934	ENOG4108JUA	Transcriptional regulator
FOKN1_0935	ENOG4105I5W	Transporter
FOKN1_0937	ENOG4105D7T	ABC transporter
FOKN1_0938	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
FOKN1_0941	ENOG4108JUA	Transcriptional regulator
FOKN1_0945	ENOG4105BZU	Histidine kinase
FOKN1_0947	ENOG4105CY0	Metallo-Beta-Lactamase
FOKN1_0948	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
FOKN1_0949	ENOG4105BZG	amino acid carrier protein
FOKN1_0950	ENOG4108WIW	Aspartyl protease
FOKN1_0955	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FOKN1_0956	ENOG4105BZU	Histidine kinase
FOKN1_0959	ENOG4105C9X	ppx gppa phosphatase
FOKN1_0962	ENOG4105E18	UPF0276 protein
FOKN1_0964	ENOG4105CSM	endonuclease III
FOKN1_0965	ENOG4105BZU	Histidine kinase
FOKN1_0966	ENOG4105DZB	Electron transport complex
FOKN1_0967	ENOG4108UQQ	Electron transport complex
FOKN1_0968	ENOG4105D6A	Electron transport complex
FOKN1_0970	ENOG4108R3D	Electron transport complex
FOKN1_0971	ENOG4105DGN	Electron transport complex
FOKN1_0972	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FOKN1_0973	ENOG4105D1F	ATP-binding protein
FOKN1_0974	ENOG4105DHP	deoxycytidine triphosphate deaminase
FOKN1_0976	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
FOKN1_0977	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
FOKN1_0978	ENOG4108J5G	6-phosphogluconate dehydrogenase
FOKN1_0980	ENOG4107QP8	phosphohexose isomerase
FOKN1_0982	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FOKN1_0983	ENOG4105C9A	Phoh family
FOKN1_0984	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
FOKN1_0985	ENOG4108JU5	Magnesium and cobalt efflux protein
FOKN1_0986	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
FOKN1_0989	ENOG4105C8T	Leucyl-tRNA synthetase
FOKN1_0991	ENOG4105DJF	DNA polymerase III, delta' subunit
FOKN1_0992	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
FOKN1_0993	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
FOKN1_0995	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
FOKN1_0996	ENOG4108Z03	MAF-like protein
FOKN1_0997	ENOG4105C03	ribonuclease
FOKN1_0998	ENOG4105QD6	exported protein
FOKN1_1001	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
FOKN1_1008	ENOG4105N42	UPF0307 protein
FOKN1_1010	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
FOKN1_1012	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FOKN1_1013	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FOKN1_1015	ENOG4105CJW	magnesium transporter
FOKN1_1016	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
FOKN1_1017	ENOG41080Z8	PHOSPHOCARRIER protein
FOKN1_1019	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
FOKN1_1021	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
FOKN1_1022	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
FOKN1_1023	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FOKN1_1024	ENOG4108IUZ	ABC transporter
FOKN1_1025	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
FOKN1_1027	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
FOKN1_1028	ENOG4105C2X	Arabinose 5-phosphate isomerase
FOKN1_1032	ENOG4105DHJ	ABC, transporter
FOKN1_1033	ENOG4105CY3	ABC transporter, permease
FOKN1_1034	ENOG4107PE3	Mammalian cell entry related domain protein
FOKN1_1037	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FOKN1_1038	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
FOKN1_1039	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
FOKN1_1040	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FOKN1_1042	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
FOKN1_1043	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FOKN1_1045	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
FOKN1_1046	ENOG4105C02	permease
FOKN1_1049	ENOG4105CS1	NAD(P)H quinone oxidoreductase
FOKN1_1050	ENOG4105K89	arsenate reductase
FOKN1_1054	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOKN1_1057	ENOG4105Y49	secretion protein, HlyD family
FOKN1_1058	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
FOKN1_1059	ENOG4108IYU	L-aspartate oxidase
FOKN1_1060	ENOG4105EMN	RNA polymerase sigma factor
FOKN1_1062	ENOG4105VQK	sigma E regulatory protein, MucB RseB
FOKN1_1064	ENOG4105C0H	protease
FOKN1_1066	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
FOKN1_1067	ENOG4105C3F	Signal peptidase i
FOKN1_1069	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FOKN1_1070	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FOKN1_1071	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
FOKN1_1072	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
FOKN1_1073	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
FOKN1_1074	ENOG4105BZU	Histidine kinase
FOKN1_1077	ENOG4105C6T	cysteine synthase
FOKN1_1081	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FOKN1_1083	ENOG4105EVH	UPF0753 protein
FOKN1_1086	ENOG4105E4C	Lytic transglycosylase catalytic
FOKN1_1087	ENOG4108TIT	dATP pyrophosphohydrolase
FOKN1_1089	ENOG4105CDY	transcriptional regulatory protein
FOKN1_1090	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
FOKN1_1091	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FOKN1_1092	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
FOKN1_1093	ENOG4107YD3	Thioesterase
FOKN1_1094	ENOG4105E02	MotA TolQ exbB proton channel
FOKN1_1095	ENOG4105M8F	Biopolymer transport protein exbD tolR
FOKN1_1097	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
FOKN1_1098	ENOG4105KCK	Peptidoglycan-associated lipoprotein
FOKN1_1100	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
FOKN1_1101	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
FOKN1_1105	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FOKN1_1109	ENOG4105C4M	(Ubiquinol oxidase) subunit I
FOKN1_1110	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
FOKN1_1119	ENOG4105C5Q	Transcriptional regulator
FOKN1_1120	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FOKN1_1127	ENOG4107ENK	receptor
FOKN1_1129	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
FOKN1_1130	ENOG4107R4I	Periplasmic binding protein
FOKN1_1131	ENOG4105EHG	Permease protein
FOKN1_1132	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
FOKN1_1135	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FOKN1_1136	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FOKN1_1137	ENOG4105DZ2	Transcriptional regulator
FOKN1_1138	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
FOKN1_1141	ENOG4105GAV	receptor
FOKN1_1145	ENOG4107ENK	receptor
FOKN1_1148	ENOG4105CGH	5'-nucleotidase
FOKN1_1149	ENOG41088H4	Diheme cytochrome SoxA (Sulfur oxidation)
FOKN1_1153	ENOG4105ERG	peptidase m48, ste24p
FOKN1_1154	ENOG41082J7	Rhodanese domain protein
FOKN1_1155	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
FOKN1_1156	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
FOKN1_1160	ENOG4105C8Q	Methyl-accepting chemotaxis
FOKN1_1161	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FOKN1_1166	ENOG4108IAB	Phoh family
FOKN1_1167	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOKN1_1168	ENOG4105RH4	Glycine cleavage system transcriptional repressor
FOKN1_1170	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FOKN1_1171	ENOG4105GJM	(LipO)protein
FOKN1_1172	ENOG4105Q2H	domain protein
FOKN1_1173	ENOG4108ETH	Formylglycinamide ribotide synthetase
FOKN1_1174	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
FOKN1_1176	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
FOKN1_1179	ENOG4105C5H	ABC transporter
FOKN1_1181	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FOKN1_1182	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
FOKN1_1183	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
FOKN1_1185	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FOKN1_1186	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
FOKN1_1187	ENOG4107YIM	Involved in the transcription termination process (By similarity)
FOKN1_1188	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
FOKN1_1189	ENOG4108ZAI	phosphatidylglycerophosphatase a
FOKN1_1191	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
FOKN1_1193	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FOKN1_1194	ENOG4105CTB	Polyprenyl synthetase
FOKN1_1195	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FOKN1_1197	ENOG4108JJA	ABC, transporter
FOKN1_1200	ENOG4105DDI	hemolysin-type calcium-binding region
FOKN1_1201	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
FOKN1_1202	ENOG4108RAC	Rubrerythrin
FOKN1_1206	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FOKN1_1207	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FOKN1_1209	ENOG4105CNA	YD repeat protein
FOKN1_1210	ENOG4105BZU	Histidine kinase
FOKN1_1212	ENOG4105F8J	Adenylate Guanylate cyclase
FOKN1_1213	ENOG4105D0M	Protease HtpX homolog
FOKN1_1215	ENOG4105BZU	Histidine kinase
FOKN1_1218	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
FOKN1_1219	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FOKN1_1220	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
FOKN1_1222	ENOG4105DHJ	ABC, transporter
FOKN1_1225	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
FOKN1_1227	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
FOKN1_1228	ENOG4105WVQ	Fe-S assembly protein IscX
FOKN1_1229	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
FOKN1_1230	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FOKN1_1232	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
FOKN1_1233	ENOG4105CUT	histidyl-tRNA synthetase
FOKN1_1235	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
FOKN1_1236	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FOKN1_1237	ENOG4105CHH	sulfate transporter
FOKN1_1239	ENOG4108I0Y	(ABC) transporter
FOKN1_1240	ENOG4108UJV	acyl-CoA thioesterase i
FOKN1_1242	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
FOKN1_1243	ENOG4105BZU	Histidine kinase
FOKN1_1245	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FOKN1_1246	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FOKN1_1247	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FOKN1_1248	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
FOKN1_1253	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FOKN1_1255	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FOKN1_1258	ENOG4108Z6B	deaminase
FOKN1_1259	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
FOKN1_1261	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FOKN1_1262	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
FOKN1_1263	ENOG4105CN8	Transcriptional regulator
FOKN1_1269	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FOKN1_1273	ENOG4105BZ1	(ABC) transporter
FOKN1_1286	ENOG4107TE5	Lipid kinase
FOKN1_1292	ENOG4109015	Biopolymer transport protein exbD tolR
FOKN1_1293	ENOG4109015	Biopolymer transport protein exbD tolR
FOKN1_1302	ENOG4105NQN	cytochrome C
FOKN1_1305	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FOKN1_1306	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
FOKN1_1307	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
FOKN1_1308	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
FOKN1_1325	ENOG4105M6W	Crispr-associated protein, Csy3 family
FOKN1_1338	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FOKN1_1345	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FOKN1_1346	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
FOKN1_1348	ENOG4105CGY	Dna recombination protein
FOKN1_1349	ENOG4105CVR	type I restriction-modification system
FOKN1_1350	ENOG41082EK	Restriction modification system DNA (Specificity
FOKN1_1356	ENOG4105C0D	helicase
FOKN1_1360	ENOG4108K8S	endonuclease I
FOKN1_1406	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FOKN1_1408	ENOG4105CJ1	ABC, transporter
FOKN1_1410	ENOG4108RRZ	Transcription elongation factor GreB
FOKN1_1414	ENOG4105CUZ	uba thif-type nad fad binding protein
FOKN1_1416	ENOG4105DP0	ferredoxin-NADP reductase
FOKN1_1417	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
FOKN1_1424	ENOG4105BZU	Histidine kinase
FOKN1_1428	ENOG4107RGJ	metallophosphoesterase
FOKN1_1432	ENOG4105WN5	stage II sporulation protein
FOKN1_1434	ENOG4105DHJ	ABC, transporter
FOKN1_1438	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FOKN1_1440	ENOG4105BZU	Histidine kinase
FOKN1_1441	ENOG4108UXN	response regulator
FOKN1_1447	ENOG4105XZC	flagellar basal body P-ring biosynthesis protein FlgA
FOKN1_1448	ENOG4107R88	Chemotaxis protein (CheV)
FOKN1_1449	ENOG4105BZU	Histidine kinase
FOKN1_1450	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
FOKN1_1451	ENOG4108ZC9	flagellar basal-body rod protein flgc
FOKN1_1452	ENOG4105W00	Flagellar hook capping protein
FOKN1_1453	ENOG4105BZE	flagellar hook protein, FlgE
FOKN1_1454	ENOG4108KPB	Flagellar basal-body rod protein FlgF
FOKN1_1455	ENOG4105CGA	flagellar basal-body rod protein FlgG
FOKN1_1456	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FOKN1_1457	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
FOKN1_1458	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
FOKN1_1459	ENOG4105E1Q	flagellar hook-associated protein
FOKN1_1461	ENOG4105BZU	Histidine kinase
FOKN1_1462	ENOG4105I03	Flagellin
FOKN1_1464	ENOG4105DTS	flagellar hook-associated
FOKN1_1465	ENOG4105MQ3	flagellar protein FliS
FOKN1_1468	ENOG4108JUA	Transcriptional regulator
FOKN1_1469	ENOG4105BZU	Histidine kinase
FOKN1_1470	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FOKN1_1471	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
FOKN1_1472	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
FOKN1_1473	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
FOKN1_1474	ENOG4108CG0	Flagellar assembly protein
FOKN1_1475	ENOG4108JIR	Flagellum-specific ATP synthase
FOKN1_1478	ENOG4105BZU	Histidine kinase
FOKN1_1482	ENOG4105C1J	atp-dependent rna helicase
FOKN1_1484	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
FOKN1_1486	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
FOKN1_1487	ENOG4105DD5	Flagellar motor switch protein
FOKN1_1488	ENOG4105VTB	flagellar biosynthesis protein fliO
FOKN1_1489	ENOG4105CN7	Flagellar biosynthetic protein FliP
FOKN1_1490	ENOG4105VS8	Flagellar biosynthetic protein fliq
FOKN1_1491	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
FOKN1_1492	ENOG4105D00	flagellar biosynthetic protein flhB
FOKN1_1493	ENOG4105D7B	Flagellar biosynthesis protein flha
FOKN1_1494	ENOG4105FZW	flagellar biosynthesis regulator FlhF
FOKN1_1496	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FOKN1_1497	ENOG4108VYJ	response regulator receiver protein
FOKN1_1498	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
FOKN1_1499	ENOG4105CBS	Chea signal transduction histidine kinase
FOKN1_1500	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FOKN1_1501	ENOG4107QJE	Chromosome Partitioning Protein
FOKN1_1504	ENOG4108V3W	Chemotaxis protein, CheW
FOKN1_1508	ENOG4105D00	flagellar biosynthetic protein flhB
FOKN1_1514	ENOG4105NBF	ammecr1 domain protein
FOKN1_1515	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
FOKN1_1519	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
FOKN1_1520	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
FOKN1_1522	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
FOKN1_1525	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
FOKN1_1526	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
FOKN1_1527	ENOG4105VIE	preprotein translocase, subunit YajC
FOKN1_1528	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FOKN1_1529	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FOKN1_1533	ENOG4105ECY	inositol monophosphatase
FOKN1_1534	ENOG4105DJ4	phosphatidylserine decarboxylase
FOKN1_1537	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
FOKN1_1538	ENOG4105D4P	Coproporphyrinogen iii oxidase
FOKN1_1540	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FOKN1_1541	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FOKN1_1543	ENOG4105EIE	fructose-bisphosphate aldolase
FOKN1_1544	ENOG4105BZU	Histidine kinase
FOKN1_1546	ENOG4108MP6	LysR family Transcriptional regulator
FOKN1_1547	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FOKN1_1549	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FOKN1_1550	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FOKN1_1556	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FOKN1_1557	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
FOKN1_1558	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FOKN1_1559	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
FOKN1_1560	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
FOKN1_1561	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FOKN1_1564	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
FOKN1_1565	ENOG4105C28	cystathionine
FOKN1_1567	ENOG4105D1Z	hydroxypyruvate reductase
FOKN1_1568	ENOG4105ED9	Protein of unknown function (DUF455)
FOKN1_1571	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
FOKN1_1572	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
FOKN1_1573	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FOKN1_1574	ENOG4105C8N	cysteinyl-tRNA synthetase
FOKN1_1576	ENOG4105BZU	Histidine kinase
FOKN1_1577	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FOKN1_1583	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FOKN1_1584	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FOKN1_1585	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
FOKN1_1586	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FOKN1_1590	ENOG4105EIN	peptidylprolyl cis-trans isomerase
FOKN1_1591	ENOG4105CK2	sodium dicarboxylate symporter
FOKN1_1592	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
FOKN1_1594	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FOKN1_1595	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FOKN1_1596	ENOG4108JQ6	ABC transporter
FOKN1_1597	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
FOKN1_1598	ENOG4105C5R	Aminotransferase
FOKN1_1600	ENOG4105DNZ	Alpha Beta Hydrolase
FOKN1_1605	ENOG4105VEQ	Cold shock protein
FOKN1_1608	ENOG4108YZN	class I peptide chain release factor
FOKN1_1610	ENOG41067HS	methyltransferase
FOKN1_1611	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FOKN1_1612	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FOKN1_1614	ENOG4106RE7	Cytochrome
FOKN1_1620	ENOG4107QRS	glycosyltransferase group 2 family protein
FOKN1_1623	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
FOKN1_1624	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
FOKN1_1625	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
FOKN1_1629	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FOKN1_1633	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
FOKN1_1640	ENOG41080HT	Transcriptional regulator, arsr family
FOKN1_1646	ENOG41089UC	methyltransferase, type 11
FOKN1_1648	ENOG4105BZU	Histidine kinase
FOKN1_1649	ENOG4105CJ3	phosphate transporter
FOKN1_1653	ENOG4105D3R	alkyl hydroperoxide reductase
FOKN1_1658	ENOG4105E9K	Isocitrate dehydrogenase
FOKN1_1659	ENOG4105BZU	Histidine kinase
FOKN1_1660	ENOG4105CJB	Exodeoxyribonuclease I
FOKN1_1665	ENOG4108YZY	peptidylprolyl cis-trans isomerase
FOKN1_1682	ENOG4105DFP	Integrase
FOKN1_1683	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
FOKN1_1684	ENOG4105C8J	)-transporter
FOKN1_1685	ENOG4108Z1B	Cyclase dehydrase
FOKN1_1686	ENOG4105VDB	UPF0125 protein
FOKN1_1687	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
FOKN1_1688	ENOG41090R7	Ferric uptake
FOKN1_1689	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FOKN1_1690	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FOKN1_1691	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
FOKN1_1692	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOKN1_1693	ENOG4105CFG	Acts as a chaperone (By similarity)
FOKN1_1694	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FOKN1_1695	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FOKN1_1696	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FOKN1_1697	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FOKN1_1698	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FOKN1_1701	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
FOKN1_1702	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FOKN1_1703	ENOG4105EEI	dihydropteroate synthase
FOKN1_1704	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FOKN1_1705	ENOG4105CP7	Triose-phosphate isomerase
FOKN1_1706	ENOG4107EJC	Preprotein translocase subunit SecG
FOKN1_1708	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FOKN1_1709	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FOKN1_1710	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FOKN1_1711	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FOKN1_1713	ENOG4107QIZ	NADH dehydrogenase
FOKN1_1715	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
FOKN1_1716	ENOG41081XG	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FOKN1_1717	ENOG4105DF2	NADH dehydrogenase subunit j
FOKN1_1718	ENOG41080FQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FOKN1_1720	ENOG4105C8S	subunit m
FOKN1_1721	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FOKN1_1726	ENOG4107QRI	Phosphoketolase
FOKN1_1727	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
FOKN1_1730	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FOKN1_1731	ENOG4105CFU	surface antigen
FOKN1_1732	ENOG4105MA0	exported protein
FOKN1_1736	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
FOKN1_1739	ENOG4108XDN	Transcriptional regulator
FOKN1_1740	ENOG4107GJV	short-chain dehydrogenase reductase
FOKN1_1746	ENOG4105BZS	acriflavin resistance protein
FOKN1_1748	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
FOKN1_1749	ENOG4105CHV	Transcription elongation factor NusA
FOKN1_1750	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FOKN1_1751	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FOKN1_1752	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FOKN1_1753	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FOKN1_1754	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FOKN1_1758	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FOKN1_1760	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
FOKN1_1761	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOKN1_1763	ENOG4105CHM	Aminotransferase
FOKN1_1765	ENOG4107S5T	Carbohydrate kinase
FOKN1_1766	ENOG4107YRI	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
FOKN1_1767	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
FOKN1_1769	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FOKN1_1772	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
FOKN1_1775	ENOG4107RSR	Malate quinone oxidoreductase
FOKN1_1776	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
FOKN1_1777	ENOG4105EU8	FAD linked oxidase domain protein
FOKN1_1778	ENOG4105CQB	FAD linked oxidase domain protein
FOKN1_1779	ENOG4105FQ6	thiopurine methyltransferase
FOKN1_1782	ENOG4105BZ4	penicillin-binding protein
FOKN1_1785	ENOG4105DVT	helicase
FOKN1_1786	ENOG41072GX	Peptidase M22 Glycoprotease
FOKN1_1790	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
FOKN1_1794	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
FOKN1_1795	ENOG4108JUA	Transcriptional regulator
FOKN1_1798	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
FOKN1_1799	ENOG4105C8Y	Acetylornithine aminotransferase
FOKN1_1801	ENOG4105DWY	Agmatine deiminase
FOKN1_1804	ENOG4105D60	lipoprotein releasing system transmembrane protein
FOKN1_1805	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FOKN1_1807	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
FOKN1_1809	ENOG4109015	Biopolymer transport protein exbD tolR
FOKN1_1810	ENOG4105BZ1	(ABC) transporter
FOKN1_1811	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
FOKN1_1812	ENOG4105W49	UPF0434 protein
FOKN1_1813	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
FOKN1_1822	ENOG4105C03	ribonuclease
FOKN1_1823	ENOG4105EI2	Pseudouridine synthase
FOKN1_1824	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FOKN1_1827	ENOG4108UHJ	MAF-like protein
FOKN1_1828	ENOG4107QSA	Oxaloacetate decarboxylase
FOKN1_1830	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FOKN1_1832	ENOG4105VGS	50s ribosomal protein l32
FOKN1_1833	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
FOKN1_1834	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FOKN1_1835	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
FOKN1_1836	ENOG4105CHR	reductase
FOKN1_1837	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FOKN1_1838	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FOKN1_1840	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
FOKN1_1841	ENOG4105HHA	aminodeoxychorismate lyase
FOKN1_1843	ENOG4105BZN	citrate synthase
FOKN1_1845	ENOG4105MPD	Cytochrome
FOKN1_1846	ENOG4108R99	pseudouridine synthase
FOKN1_1847	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
FOKN1_1848	ENOG4107QRG	dna polymerase iii
FOKN1_1850	ENOG4105F8V	Hydrolase, tatD family
FOKN1_1852	ENOG4105NAU	thioesterase Superfamily protein
FOKN1_1853	ENOG4108IQE	Amp-dependent synthetase and ligase
FOKN1_1854	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
FOKN1_1855	ENOG4105CHU	acetyl-coa acetyltransferase
FOKN1_1856	ENOG4107QPN	acyl-Coa dehydrogenase
FOKN1_1858	ENOG4105C9B	Cysteine desulfurase
FOKN1_1862	ENOG4105EM7	Selenocysteine-specific translation elongation factor
FOKN1_1868	ENOG4108UVJ	appr-1-p processing domain protein
FOKN1_1870	ENOG4105DS1	cytochrome b561
FOKN1_1872	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FOKN1_1873	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FOKN1_1877	ENOG4107RIQ	Sulfate adenylate transferase
FOKN1_1879	ENOG4107PU6	Membrane
FOKN1_1880	ENOG4107QN2	dihydrolipoyl dehydrogenase
FOKN1_1881	ENOG4105C7S	Dehydrogenase
FOKN1_1882	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
FOKN1_1883	ENOG4105D8X	mechanosensitive ion channel
FOKN1_1887	ENOG4108SVW	integral membrane protein
FOKN1_1891	ENOG4107R1Y	fructose-bisphosphate aldolase
FOKN1_1896	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
FOKN1_1897	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FOKN1_1898	ENOG4105E50	uracil-dna glycosylase
FOKN1_1899	ENOG4105WH1	Two component transcriptional regulator luxr family
FOKN1_1906	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FOKN1_1922	ENOG4108MN8	Membrane
FOKN1_1934	ENOG4105SUU	thioesterase domain
FOKN1_1935	ENOG4105P69	integral membrane protein
FOKN1_1936	ENOG4106TD9	Diguanylate cyclase
FOKN1_1939	ENOG4107E2E	PKHD-type hydroxylase
FOKN1_1945	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
FOKN1_1946	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
FOKN1_1947	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
FOKN1_1948	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
FOKN1_1950	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
FOKN1_1955	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
FOKN1_1958	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FOKN1_1960	ENOG4105BZU	Histidine kinase
FOKN1_1961	ENOG4105WH1	Two component transcriptional regulator luxr family
FOKN1_1963	ENOG4107QW3	Sucrose phosphorylase
FOKN1_1964	ENOG4105CEP	NADH dehydrogenase
FOKN1_1967	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
FOKN1_1969	ENOG4105CD8	aminopeptidase N
FOKN1_1973	ENOG4105BZU	Histidine kinase
FOKN1_1975	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
FOKN1_1977	ENOG4105WMR	Protein CrcB homolog
FOKN1_1978	ENOG4105D1H	recombination factor protein RarA
FOKN1_1979	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
FOKN1_1980	ENOG4105CNU	cell division protein FtsK
FOKN1_1981	ENOG4105DCF	alanine dehydrogenase
FOKN1_1982	ENOG4105C3M	thioredoxin reductase
FOKN1_1984	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
FOKN1_1985	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
FOKN1_1986	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
FOKN1_1987	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FOKN1_1988	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
FOKN1_1989	ENOG4105VEQ	Cold shock protein
FOKN1_1994	ENOG41075W9	High frequency lysogenization protein HflD homolog
FOKN1_1995	ENOG4105BZU	Histidine kinase
FOKN1_1996	ENOG4107QM5	aconitate hydratase
FOKN1_1997	ENOG4107QTF	adenylosuccinate lyase
FOKN1_2003	ENOG4105X7T	Ni Fe-hydrogenase, b-type cytochrome subunit
FOKN1_2010	ENOG4105CJW	magnesium transporter
FOKN1_2013	ENOG4105Q9Y	Universal stress protein
FOKN1_2017	ENOG4107WUB	V-type ATPase 116 kDa subunit
FOKN1_2021	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
FOKN1_2022	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
FOKN1_2027	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
FOKN1_2029	ENOG4105EAQ	(twin-arginine translocation) pathway signal
FOKN1_2031	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FOKN1_2034	ENOG4105D6E	homoserine dehydrogenase
FOKN1_2035	ENOG4105CHM	Aminotransferase
FOKN1_2037	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FOKN1_2038	ENOG4108K5P	(LipO)protein
FOKN1_2039	ENOG4108UM1	dedA family
FOKN1_2040	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
FOKN1_2041	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
FOKN1_2042	ENOG4105C98	muts2 protein
FOKN1_2043	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
FOKN1_2049	ENOG4108F3G	Type I restriction-modification system, R subunit
FOKN1_2050	ENOG4108UK5	Transposase
FOKN1_2051	ENOG4107XZC	Restriction modification system DNA (Specificity
FOKN1_2052	ENOG4105CVR	type I restriction-modification system
FOKN1_2053	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
FOKN1_2054	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
FOKN1_2055	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
FOKN1_2056	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FOKN1_2057	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
FOKN1_2058	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FOKN1_2059	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FOKN1_2060	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
FOKN1_2061	ENOG4105C0B	DNA polymerase III (alpha subunit)
FOKN1_2062	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FOKN1_2063	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FOKN1_2064	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
FOKN1_2067	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FOKN1_2068	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FOKN1_2069	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FOKN1_2070	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FOKN1_2073	ENOG4105DZP	Membrane-associated zinc metalloprotease
FOKN1_2074	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
FOKN1_2075	ENOG4105KNE	Phosphatidate cytidylyltransferase
FOKN1_2076	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FOKN1_2077	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
FOKN1_2078	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FOKN1_2079	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FOKN1_2080	ENOG4105CE9	30S ribosomal protein S2
FOKN1_2081	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
FOKN1_2082	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
FOKN1_2088	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
FOKN1_2089	ENOG4105D65	subunit l
FOKN1_2090	ENOG4108ZE9	Monovalent cation H antiporter subunit C
FOKN1_2091	ENOG4107R4Z	monovalent cation h antiporter subunit d
FOKN1_2093	ENOG4105W4C	monovalent cation H antiporter subunit F
FOKN1_2094	ENOG4105KJM	monovalent cation h antiporter subunit g
FOKN1_2098	ENOG4105EYW	Ion transport protein
FOKN1_2102	ENOG4105D6J	arsenicaL-resistance protein
FOKN1_2103	ENOG4108UXE	Protein tyrosine phosphatase
FOKN1_2104	ENOG41082YX	Transcriptional regulator, arsr family
FOKN1_2105	ENOG4105BZU	Histidine kinase
FOKN1_2106	ENOG4105KUZ	arsenate reductase
FOKN1_2107	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FOKN1_2111	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
FOKN1_2112	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
FOKN1_2114	ENOG4108ZZ3	UPF0260 protein
FOKN1_2115	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
FOKN1_2116	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
FOKN1_2117	ENOG4108JA2	transcriptioN-repair coupling factor
FOKN1_2119	ENOG41065DM	this blockage is overcome by subsequent expression of antitoxin YafN. Overexpression causes cleavage of a number of mRNAs in a ribosome-dependent fashion. YafO binding to the 50S ribosomal subunit in the translation complex induces mRNA cleavage 3' to the region protected by the ribosome
FOKN1_2120	ENOG4105UG9	Antitoxin of the YafO-YafN toxin-antitoxin system
FOKN1_2124	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
FOKN1_2125	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOKN1_2126	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
FOKN1_2127	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
FOKN1_2128	ENOG4105D78	K07001 NTE family protein
FOKN1_2129	ENOG4105D64	Mechanosensitive ion channel
FOKN1_2130	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
FOKN1_2131	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
FOKN1_2132	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
FOKN1_2135	ENOG41080ZE	Adenylate cyclase
FOKN1_2136	ENOG4105Y75	tpr repeat protein
FOKN1_2137	ENOG4105E33	succinate dehydrogenase
FOKN1_2139	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
FOKN1_2141	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
FOKN1_2142	ENOG4105BZU	Histidine kinase
FOKN1_2143	ENOG4105CRK	lysyL-tRNA synthetase
FOKN1_2144	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
FOKN1_2145	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
FOKN1_2148	ENOG4105WJX	transcriptional regulator MERR family
FOKN1_2149	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FOKN1_2150	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
FOKN1_2151	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FOKN1_2152	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FOKN1_2153	ENOG41082NX	50s ribosomal protein l35
FOKN1_2154	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
FOKN1_2155	ENOG4105C22	threonyL-tRNA synthetase
FOKN1_2157	ENOG4105CA0	peroxidase
FOKN1_2158	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
FOKN1_2161	ENOG4105CHM	Aminotransferase
FOKN1_2163	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
FOKN1_2165	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
FOKN1_2166	ENOG4105D3Q	Sugar transferase
FOKN1_2173	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
FOKN1_2174	ENOG4105KQC	Competence protein
FOKN1_2175	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
FOKN1_2176	ENOG4105CFV	Tetratricopeptide repeat protein
FOKN1_2178	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
FOKN1_2179	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FOKN1_2180	ENOG4105CAT	Cytidine monophosphate kinase
FOKN1_2181	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
FOKN1_2183	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FOKN1_2186	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
FOKN1_2187	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FOKN1_2188	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
FOKN1_2192	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
FOKN1_2193	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
FOKN1_2194	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FOKN1_2196	ENOG4105FBD	synthase
FOKN1_2197	ENOG4105FE1	phytoene synthase
FOKN1_2199	ENOG4105UBK	short-chain dehydrogenase reductase
FOKN1_2201	ENOG4105BZU	Histidine kinase
FOKN1_2203	ENOG4105FE9	pseudouridine synthase
FOKN1_2204	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
FOKN1_2206	ENOG4105C31	Tryptophanyl-tRNA synthetase
FOKN1_2207	ENOG4108Z4T	Peptidase M50
FOKN1_2208	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
FOKN1_2209	ENOG4105DB7	PHP domain protein
FOKN1_2210	ENOG4107835	probably involved in intracellular septation (By similarity)
FOKN1_2211	ENOG4105K9H	YciI-like protein
FOKN1_2213	ENOG4107TF3	peptidylprolyl cis-trans isomerase
FOKN1_2217	ENOG4105EYA	deoxyribonuclease
FOKN1_2218	ENOG4106N16	had-superfamily hydrolase, subfamily iib
FOKN1_2222	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FOKN1_2227	ENOG4105W08	virulence gene repressor rsal
FOKN1_2228	ENOG4105W2W	Cytotoxic translational repressor of toxin-antitoxin stability system
FOKN1_2234	ENOG4107QTH	restriction modification system DNA specificity domain
FOKN1_2244	ENOG4105CMM	transposase
FOKN1_2249	ENOG4105DAN	ATP-dependent protease
FOKN1_2250	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
FOKN1_2253	ENOG4105DCG	PHP domain protein
FOKN1_2254	ENOG4105D2N	Aldolase
FOKN1_2256	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FOKN1_2260	ENOG4105C94	Transporter
FOKN1_2262	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
FOKN1_2269	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOKN1_2272	ENOG4105C45	hydrogenase expression formation protein (HypE)
FOKN1_2276	ENOG4105D78	K07001 NTE family protein
FOKN1_2279	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
FOKN1_2280	ENOG4105D5B	Sulfite reductase, subunit A
FOKN1_2282	ENOG4105DPX	Hydrogenase, large subunit
FOKN1_2285	ENOG4105E3S	small subunit
FOKN1_2289	ENOG41083WG	hydrogenase assembly chaperone
FOKN1_2290	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
FOKN1_2291	ENOG4107RSS	Hydrogenase accessory protein HypB
FOKN1_2292	ENOG4105CQS	hydrogenase expression formation protein HypD
FOKN1_2297	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
FOKN1_2300	ENOG4105C0H	protease
FOKN1_2303	ENOG4107RDJ	Sulfotransferase
FOKN1_2307	ENOG4105C3K	feS assembly ATPase SufC
FOKN1_2309	ENOG4105VG1	fes assembly suf system protein
FOKN1_2310	ENOG4108Z4V	iron-sulfur cluster assembly
FOKN1_2311	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
FOKN1_2313	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
FOKN1_2320	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
FOKN1_2321	ENOG4105CPK	Glycosyl transferase (Group 1
FOKN1_2322	ENOG4105CAQ	asparagine synthetase
FOKN1_2323	ENOG4108KMV	Glycosyl transferase (Group 1
FOKN1_2328	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
FOKN1_2331	ENOG4108QV3	biosynthesis protein
FOKN1_2333	ENOG4107V1M	polysaccharide export protein
FOKN1_2335	ENOG4105D06	uba thif-type nad fad binding protein
FOKN1_2340	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FOKN1_2341	ENOG4105BZU	Histidine kinase
FOKN1_2345	ENOG4107QQG	Dehydrogenase
FOKN1_2346	ENOG4107QQG	Dehydrogenase
FOKN1_2347	ENOG4108JDX	DNA polymerase iii, epsilon subunit
FOKN1_2348	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FOKN1_2350	ENOG4105E9H	Lytic Murein transglycosylase
FOKN1_2352	ENOG41082CS	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
FOKN1_2353	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
FOKN1_2357	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
FOKN1_2360	ENOG4107YU2	histidine triad (hIT) protein
FOKN1_2368	ENOG4107QN1	sodium solute
FOKN1_2371	ENOG4105BZU	Histidine kinase
FOKN1_2372	ENOG4105BZU	Histidine kinase
FOKN1_2374	ENOG4105K34	Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the cleavage of phosphorylated 4,5- dihydroxy-2,3-pentanedione (P-DPD) to 2-phosphoglycolic acid (PG) and another three-carbon compound
FOKN1_2375	ENOG4105C0A	alcohol dehydrogenase
FOKN1_2377	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
FOKN1_2379	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
FOKN1_2381	ENOG4105D82	Glutamate dehydrogenase
FOKN1_2383	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
FOKN1_2384	ENOG4105D0M	Protease HtpX homolog
FOKN1_2386	ENOG41090A4	Pterin carbinolamine dehydratase
FOKN1_2387	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
FOKN1_2388	ENOG4107YU2	histidine triad (hIT) protein
FOKN1_2391	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
FOKN1_2392	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
FOKN1_2393	ENOG4107QMP	dna polymerase iii subunits gamma and tau
FOKN1_2397	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FOKN1_2399	ENOG4105EUB	pirin domain protein
FOKN1_2400	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
FOKN1_2405	ENOG4105EVH	UPF0753 protein
FOKN1_2406	ENOG4105D65	subunit l
FOKN1_2408	ENOG4105CA0	peroxidase
FOKN1_2410	ENOG4105CBX	hi0933 family
FOKN1_2411	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FOKN1_2412	ENOG4105BZU	Histidine kinase
FOKN1_2413	ENOG4105E39	Enoyl-CoA hydratase
FOKN1_2414	ENOG4105BZU	Histidine kinase
FOKN1_2415	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
FOKN1_2420	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
FOKN1_2422	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
FOKN1_2423	ENOG4105CFH	Aspartokinase
FOKN1_2424	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FOKN1_2425	ENOG4105Y3E	Modulates RecA activity (By similarity)
FOKN1_2426	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FOKN1_2428	ENOG4107TH8	cina domain protein
FOKN1_2430	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FOKN1_2431	ENOG4108W2P	Methyl-accepting chemotaxis
FOKN1_2433	ENOG4108KTQ	Methyltransferase
FOKN1_2435	ENOG4105CBS	Chea signal transduction histidine kinase
FOKN1_2438	ENOG4108Z4U	Ferredoxin
FOKN1_2440	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
FOKN1_2441	ENOG4107QR8	Thioredoxin
FOKN1_2442	ENOG4105T95	Thiol disulfide interChange protein
FOKN1_2443	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FOKN1_2444	ENOG4107RCI	amp-dependent synthetase and ligase
FOKN1_2448	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
FOKN1_2449	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
FOKN1_2450	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FOKN1_2451	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FOKN1_2452	ENOG41080RH	Thioredoxin
FOKN1_2453	ENOG4105BZU	Histidine kinase
FOKN1_2459	ENOG4105CHH	sulfate transporter
FOKN1_2461	ENOG4105VEJ	Heat shock protein
FOKN1_2462	ENOG4107ZXU	DSBA oxidoreductase
FOKN1_2463	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
FOKN1_2464	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FOKN1_2466	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FOKN1_2467	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FOKN1_2468	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
FOKN1_2469	ENOG4105K5M	30s ribosomal protein S16
FOKN1_2470	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOKN1_2472	ENOG4106KVJ	cytochrome C assembly protein
FOKN1_2473	ENOG4108JU6	CBS domain protein
FOKN1_2475	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
FOKN1_2477	ENOG4105F8J	Adenylate Guanylate cyclase
FOKN1_2480	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FOKN1_2481	ENOG4105CDU	Replicative dna helicase
FOKN1_2482	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FOKN1_2484	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
FOKN1_2485	ENOG4108VDV	Binds single-stranded DNA at the primosome assembly site (PAS) (By similarity)
FOKN1_2486	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
FOKN1_2487	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FOKN1_2488	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
FOKN1_2489	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FOKN1_2492	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FOKN1_2493	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
FOKN1_2495	ENOG4105EPW	hflc protein
FOKN1_2496	ENOG4107QJR	hflk protein
FOKN1_2497	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
FOKN1_2498	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
FOKN1_2499	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FOKN1_2500	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FOKN1_2501	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FOKN1_2502	ENOG4105K8N	protein family UPF0079, ATPase
FOKN1_2503	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FOKN1_2504	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
FOKN1_2505	ENOG4105CFP	Peptidase U32
FOKN1_2506	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
FOKN1_2508	ENOG41082RQ	UPF0102 protein
FOKN1_2509	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
FOKN1_2510	ENOG4105W4M	Transport-associated protein
FOKN1_2512	ENOG4105BZU	Histidine kinase
FOKN1_2513	ENOG4105BZU	Histidine kinase
FOKN1_2522	ENOG4105KPY	Small multidrug resistance protein
FOKN1_2523	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
FOKN1_2524	ENOG41080ET	plasmid maintenance system killer protein
FOKN1_2526	ENOG4105DQ6	Transposase
FOKN1_2540	ENOG4105KB2	stringent starvation protein b
FOKN1_2541	ENOG4107MKT	Stringent starvation protein a
FOKN1_2542	ENOG4105EIX	cytochrome c1
FOKN1_2543	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FOKN1_2544	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
FOKN1_2545	ENOG4107QNR	UPF0135 protein
FOKN1_2546	ENOG4105C0H	protease
FOKN1_2547	ENOG4105M2J	Glutaredoxin
FOKN1_2548	ENOG4105CAQ	asparagine synthetase
FOKN1_2552	ENOG4105C8Y	Acetylornithine aminotransferase
FOKN1_2553	ENOG4105DBV	ornithine carbamoyltransferase
FOKN1_2554	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
FOKN1_2555	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FOKN1_2556	ENOG4105E2Z	phosphate ABC transporter (Permease
FOKN1_2557	ENOG4105C8U	phosphate abc transporter
FOKN1_2559	ENOG4105CDH	Citrulline--aspartate ligase
FOKN1_2563	ENOG4108JYK	Dehydrogenase
FOKN1_2564	ENOG4105EKE	dihydroorotase
FOKN1_2566	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
FOKN1_2569	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
FOKN1_2572	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
FOKN1_2573	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
FOKN1_2574	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
FOKN1_2575	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
FOKN1_2576	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FOKN1_2577	ENOG4105DJ0	Poly(A) Polymerase
FOKN1_2583	ENOG4108K5H	permease YjgP YjgQ family protein
FOKN1_2584	ENOG4108M8S	permease YjgP YjgQ family protein
FOKN1_2585	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
FOKN1_2587	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
FOKN1_2588	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FOKN1_2589	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
FOKN1_2594	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
FOKN1_2595	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
FOKN1_2597	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
FOKN1_2598	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FOKN1_2603	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FOKN1_2604	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
FOKN1_2605	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
FOKN1_2606	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
FOKN1_2607	ENOG4108ZP8	Acetolactate synthase small subunit
FOKN1_2608	ENOG4105C7K	acetolactate synthase
FOKN1_2610	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FOKN1_2611	ENOG4105C9M	aspartyl-trna synthetase
FOKN1_2614	ENOG4108JJ7	ABC transporter
FOKN1_2620	ENOG4105ER2	Ompa motb domain protein
FOKN1_2621	ENOG4105E14	MotA TolQ exbB proton channel
FOKN1_2622	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
FOKN1_2623	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FOKN1_2625	ENOG4105E1F	short-chain dehydrogenase reductase
FOKN1_2628	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FOKN1_2630	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FOKN1_2631	ENOG4105VUC	UPF0237 protein
FOKN1_2633	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
FOKN1_2634	ENOG4105C34	Pseudouridine synthase
FOKN1_2636	ENOG4108YZA	Nitrogen regulatory protein pii
FOKN1_2638	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
FOKN1_2639	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
FOKN1_2641	ENOG4107TUY	Histidine kinase
FOKN1_2642	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FOKN1_2647	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
FOKN1_2648	ENOG4107QHF	type ii secretion system protein e
FOKN1_2651	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
FOKN1_2652	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
FOKN1_2653	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
FOKN1_2656	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
FOKN1_2657	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FOKN1_2658	ENOG4105DR5	peptidase
FOKN1_2660	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FOKN1_2661	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FOKN1_2662	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
FOKN1_2663	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
FOKN1_2664	ENOG4105CPF	Cell wall formation (By similarity)
FOKN1_2665	ENOG4105D4A	Cell wall formation (By similarity)
FOKN1_2667	ENOG4105DFU	Cell wall formation (By similarity)
FOKN1_2668	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
FOKN1_2669	ENOG4105CNI	cell division protein FtsW
FOKN1_2670	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FOKN1_2671	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FOKN1_2672	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
FOKN1_2673	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FOKN1_2674	ENOG4105CJN	penicillin-binding protein
FOKN1_2675	ENOG41063Y6	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
FOKN1_2676	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
FOKN1_2677	ENOG4108V6E	Cell division protein mraZ
FOKN1_2679	ENOG4108UUM	single-stranded DNA-binding protein
FOKN1_2680	ENOG4107RDB	Major Facilitator
FOKN1_2683	ENOG4108ZT0	50S ribosomal protein l17
FOKN1_2684	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FOKN1_2685	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FOKN1_2686	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FOKN1_2687	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOKN1_2688	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
FOKN1_2689	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FOKN1_2690	ENOG4105VPB	50S ribosomal protein L30
FOKN1_2691	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FOKN1_2692	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
FOKN1_2693	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FOKN1_2694	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
FOKN1_2695	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FOKN1_2696	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FOKN1_2697	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FOKN1_2698	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FOKN1_2699	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FOKN1_2700	ENOG41083MP	50s ribosomal protein l29
FOKN1_2701	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FOKN1_2702	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FOKN1_2703	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FOKN1_2704	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FOKN1_2705	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOKN1_2706	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FOKN1_2707	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FOKN1_2708	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FOKN1_2709	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FOKN1_2710	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FOKN1_2711	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FOKN1_2712	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FOKN1_2713	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FOKN1_2714	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FOKN1_2715	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FOKN1_2716	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FOKN1_2717	ENOG4108VZM	50s ribosomal protein L10
FOKN1_2718	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FOKN1_2719	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FOKN1_2720	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
FOKN1_2721	ENOG4105PM1	preprotein translocase subunit SecE
FOKN1_2723	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FOKN1_2727	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
FOKN1_2729	ENOG4105E09	nadh pyrophosphatase
FOKN1_2733	ENOG4108Q5Y	Membrane
FOKN1_2737	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
FOKN1_2738	ENOG4108M1M	outer membrane lipoprotein-sorting protein
FOKN1_2742	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
FOKN1_2743	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
FOKN1_2752	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FOKN1_2753	ENOG4105DR5	peptidase
FOKN1_2755	ENOG4105BZN	citrate synthase
FOKN1_2756	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
FOKN1_2759	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
FOKN1_2762	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOKN1_2766	ENOG4108UQY	Iron-storage protein
FOKN1_2768	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
FOKN1_2769	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FOKN1_2772	ENOG4105E0A	ABC, transporter
FOKN1_2776	ENOG410822N	TonB family
FOKN1_2777	ENOG4108WBT	adenosyltransferase
FOKN1_2778	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
FOKN1_2779	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
FOKN1_2783	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOKN1_2792	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
FOKN1_2796	ENOG4105CQ7	ATP-dependent helicase
FOKN1_2798	ENOG4105DEU	major facilitator superfamily
FOKN1_2800	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
FOKN1_2803	ENOG4105C7Z	Conserved Protein
FOKN1_2808	ENOG4107RQ2	Cytochrome c oxidase, subunit I
FOKN1_2810	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FOKN1_2811	ENOG4105PWE	CRISPR-associated protein cas2
FOKN1_2812	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
FOKN1_2815	ENOG41060M0	Crispr-associated protein, cse4 family
FOKN1_2818	ENOG4105DTT	CRISPR-associated helicase, cas3
FOKN1_2822	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
FOKN1_2824	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FOKN1_2825	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
FOKN1_2827	ENOG4107QI6	Cysteine desulfurase
FOKN1_2829	ENOG4105C3G	gtp-binding protein
FOKN1_2830	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FOKN1_2831	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
FOKN1_2832	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FOKN1_2834	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
FOKN1_2835	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
FOKN1_2836	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
FOKN1_2837	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
FOKN1_2838	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FOKN1_2839	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FOKN1_2841	ENOG4105D06	uba thif-type nad fad binding protein
FOKN1_2843	ENOG4108R5S	membrane
FOKN1_2844	ENOG4106N16	had-superfamily hydrolase, subfamily iib
FOKN1_2846	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FOKN1_2847	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
FOKN1_2848	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FOKN1_2849	ENOG4105DFF	Rod shape-determining protein mreb
FOKN1_2850	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
FOKN1_2851	ENOG4105VQ7	Rod shape-determining protein MreD
FOKN1_2852	ENOG4105CJN	penicillin-binding protein
FOKN1_2853	ENOG4105CNI	cell division protein FtsW
FOKN1_2854	ENOG4105CVE	Lytic murein transglycosylase
FOKN1_2855	ENOG4105K6T	rare lipoprotein A
FOKN1_2856	ENOG4105DZ1	carboxypeptidase
FOKN1_2857	ENOG4105F0I	Aminotransferase
FOKN1_2862	ENOG4108Z43	UPF0250 protein
FOKN1_2863	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
FOKN1_2864	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
FOKN1_2870	ENOG4108S0S	Nucleotidyl transferase
FOKN1_2871	ENOG4105EHM	Aminoglycoside phosphotransferase
FOKN1_2874	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
FOKN1_2875	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
FOKN1_2876	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
FOKN1_2877	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FOKN1_2879	ENOG41081QV	Universal stress protein
FOKN1_2884	ENOG4105NWN	ApaG protein
FOKN1_2888	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
FOKN1_2890	ENOG4105DR4	Methyltransferase
FOKN1_2894	ENOG4105CKK	Glycosyl transferase, family 2
FOKN1_2895	ENOG4105C7Z	Conserved Protein
FOKN1_2896	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
FOKN1_2897	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
FOKN1_2898	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
FOKN1_2900	ENOG4105BZU	Histidine kinase
FOKN1_2902	ENOG41080IJ	Diacylglycerol kinase
FOKN1_2903	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOKN1_2904	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
FOKN1_2905	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOKN1_2906	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
FOKN1_2907	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
FOKN1_2909	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
FOKN1_2910	ENOG4105D0A	hydroxylase
FOKN1_2911	ENOG4107RAQ	aminopeptidase
FOKN1_2914	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
FOKN1_2916	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
FOKN1_2919	ENOG4105C7B	Threonine dehydratase
FOKN1_2920	ENOG4105E66	phosphoriboisomerase A
FOKN1_2921	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
FOKN1_2922	ENOG4108Z9W	Outer membrane porin
FOKN1_2923	ENOG4105EIF	outer membrane protein W
FOKN1_2925	ENOG4108UJD	30S ribosomal protein S9
FOKN1_2926	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FOKN1_2929	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
FOKN1_2930	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
FOKN1_2932	ENOG4108UKZ	OsmC family
FOKN1_2933	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
FOKN1_2934	ENOG4105DK0	Indole-3-glycerol phosphate synthase
FOKN1_2935	ENOG4108I0Q	anthranilate phosphoribosyltransferase
FOKN1_2936	ENOG4105DDQ	anthranilate synthase
FOKN1_2938	ENOG4105CRQ	synthase (Component I)
FOKN1_2939	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
FOKN1_2943	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
FOKN1_2945	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
FOKN1_2948	ENOG4108KPW	sugar kinase
FOKN1_2958	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FOKN1_2960	ENOG4105VN1	Heat shock protein
FOKN1_2967	ENOG4105CPI	Metal Dependent Phosphohydrolase
FOKN1_2971	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
FOKN1_2972	ENOG4105E0C	molybdate abc transporter
FOKN1_2973	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
FOKN1_2976	ENOG4107W2M	Sodium hydrogen exchanger
FOKN1_2979	ENOG4105D2N	Aldolase
FOKN1_2980	ENOG4105CA9	Pyruvate kinase
FOKN1_2981	ENOG4105BZA	Phosphoglycerate kinase
FOKN1_2982	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FOKN1_2983	ENOG4105CV1	Transketolase (EC 2.2.1.1)
FOKN1_2986	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FOKN1_2987	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
FOKN1_2988	ENOG4105SYT	Methylenetetrahydrofolate reductase
FOKN1_2989	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
FOKN1_2991	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FOKN1_2994	ENOG4105C8P	)-transporter
FOKN1_2997	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FOKN1_2998	ENOG4105CBS	Chea signal transduction histidine kinase
FOKN1_2999	ENOG4105BZU	Histidine kinase
FOKN1_3000	ENOG4105C8Q	Methyl-accepting chemotaxis
FOKN1_3001	ENOG4108ZGA	chew protein
FOKN1_3002	ENOG4105M3Z	response regulator
FOKN1_3003	ENOG4108UNF	response regulator
FOKN1_3005	ENOG4105D7Z	glutathione synthase
FOKN1_3006	ENOG41081YB	ApbE family
FOKN1_3011	ENOG4108UJU	UPF0301 protein
FOKN1_3012	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
FOKN1_3014	ENOG4105CXT	aspartate transcarbamylase
FOKN1_3015	ENOG4105CD3	dihydroorotase
FOKN1_3018	ENOG4105CZX	twitching motility protein
FOKN1_3019	ENOG4105CZX	twitching motility protein
FOKN1_3020	ENOG4105DFA	alanine racemase domain protein
FOKN1_3021	ENOG4105II7	pyrroline-5-carboxylate reductase
FOKN1_3022	ENOG4108VIA	integral membrane protein
FOKN1_3023	ENOG4105VZ9	UPF0235 protein
FOKN1_3027	ENOG4105CGK	Exodeoxyribonuclease III
FOKN1_3028	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FOKN1_3031	ENOG4105CAS	nag kinase
FOKN1_3033	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
FOKN1_3034	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
FOKN1_3035	ENOG4105W5Q	DNA repair protein (RadC
FOKN1_3036	ENOG4105KDC	50s ribosomal protein l28
FOKN1_3037	ENOG4105W0E	50S ribosomal protein L33
FOKN1_3040	ENOG4105D58	Diguanylate phosphodiesterase
FOKN1_3042	ENOG4105DA5	(ABC) transporter
FOKN1_3046	ENOG4107QN2	dihydrolipoyl dehydrogenase
FOKN1_3047	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
FOKN1_3050	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
FOKN1_3051	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FOKN1_3052	ENOG4106H78	methyltransferase
FOKN1_3054	ENOG4105C1V	Peptidase, M16
FOKN1_3056	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FOKN1_3057	ENOG4105CAK	Cell division ATP-binding protein ftsE
FOKN1_3058	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
FOKN1_3059	ENOG4105BZU	Histidine kinase
FOKN1_3060	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FOKN1_3063	ENOG4107R50	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FOKN1_3068	ENOG4105VEQ	Cold shock protein
FOKN1_3072	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FOKN1_3073	ENOG4105BZU	Histidine kinase