locus-tag	class	description
FOKN1_0010	COG2391	methyltransferase activity
FOKN1_0011	COG0425	Belongs to the sulfur carrier protein TusA family
FOKN1_0012	COG0450	alkyl hydroperoxide reductase
FOKN1_0019	COG2217	Heavy metal translocating P-type atpase
FOKN1_0021	COG0348	domain, Protein
FOKN1_0022	COG2010	Cytochrome c
FOKN1_0025	COG3278	Belongs to the heme-copper respiratory oxidase family
FOKN1_0026	COG0109	protoheme IX farnesyltransferase activity
FOKN1_0028	COG3346	SURF1 family
FOKN1_0032	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOKN1_0036	COG2226	methyltransferase
FOKN1_0037	COG0596	Alpha beta hydrolase
FOKN1_0038	COG0156	8-amino-7-oxononanoate synthase activity
FOKN1_0039	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOKN1_0041	COG1040	competence protein
FOKN1_0045	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FOKN1_0046	COG3161	chorismate lyase activity
FOKN1_0047	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FOKN1_0049	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOKN1_0050	COG1758	RNA polymerase activity
FOKN1_0051	COG0194	GDP metabolic process
FOKN1_0052	COG1561	YicC-like family, N-terminal region
FOKN1_0053	COG2815	serine threonine protein kinase
FOKN1_0053	COG0515	serine threonine protein kinase
FOKN1_0054	COG0631	protein serine/threonine phosphatase activity
FOKN1_0055	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
FOKN1_0056	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
FOKN1_0057	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FOKN1_0060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOKN1_0062	COG0254	rRNA binding
FOKN1_0065	COG0281	malic enzyme
FOKN1_0073	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
FOKN1_0074	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
FOKN1_0075	COG0232	Belongs to the dGTPase family. Type 2 subfamily
FOKN1_0078	COG0069	glutamate synthase activity
FOKN1_0078	COG0067	glutamate synthase
FOKN1_0078	COG0070	glutamate synthase
FOKN1_0080	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
FOKN1_0085	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FOKN1_0086	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FOKN1_0087	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
FOKN1_0089	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FOKN1_0090	COG0018	arginyl-trna synthetase
FOKN1_0092	COG4772	TonB-dependent receptor
FOKN1_0095	COG2084	Dehydrogenase
FOKN1_0096	COG1166	arginine decarboxylase activity
FOKN1_0097	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
FOKN1_0098	COG0390	transport system, permease component
FOKN1_0099	COG1136	(ABC) transporter
FOKN1_0100	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
FOKN1_0101	COG5001	Diguanylate cyclase
FOKN1_0101	COG5002	protein histidine kinase activity
FOKN1_0103	COG0210	DNA helicase
FOKN1_0106	COG0842	Transport permease protein
FOKN1_0107	COG1129	ABC transporter
FOKN1_0107	COG0842	Transport permease protein
FOKN1_0108	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOKN1_0112	COG3384	dioxygenase
FOKN1_0113	COG3153	acetyltransferase
FOKN1_0114	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FOKN1_0114	COG0069	glutamate synthase activity
FOKN1_0115	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
FOKN1_0116	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOKN1_0119	COG1671	Belongs to the UPF0178 family
FOKN1_0123	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
FOKN1_0127	COG2703	oxygen carrier activity
FOKN1_0130	COG1388	LysM domain
FOKN1_0130	COG0791	NLP P60 protein
FOKN1_0131	COG0517	IMP dehydrogenase activity
FOKN1_0131	COG1125	glycine betaine transport
FOKN1_0134	COG0045	succinate-CoA ligase (ADP-forming) activity
FOKN1_0134	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FOKN1_0134	COG1042	CoA-binding domain protein
FOKN1_0135	COG0123	including yeast histone deacetylase and acetoin utilization protein
FOKN1_0137	COG0672	)-iron permease
FOKN1_0139	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOKN1_0139	COG0543	2 iron, 2 sulfur cluster binding
FOKN1_0142	COG3094	Invasion gene expression up-regulator, SirB
FOKN1_0149	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOKN1_0160	COG0210	DNA helicase
FOKN1_0163	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FOKN1_0164	COG0167	dihydroorotate dehydrogenase activity
FOKN1_0168	COG1450	Type ii and iii secretion system protein
FOKN1_0171	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FOKN1_0172	COG1459	type II secretion system
FOKN1_0179	COG2204	response regulator
FOKN1_0180	COG3852	Histidine kinase
FOKN1_0182	COG0174	glutamine synthetase
FOKN1_0185	COG0482	sulfurtransferase activity
FOKN1_0188	COG0752	glycyl-tRNA synthetase alpha subunit
FOKN1_0189	COG0751	glycine-tRNA ligase activity
FOKN1_0191	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
FOKN1_0193	COG0187	DNA topoisomerase II activity
FOKN1_0194	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
FOKN1_0196	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
FOKN1_0197	COG0230	Belongs to the bacterial ribosomal protein bL34 family
FOKN1_0198	COG0594	ribonuclease P activity
FOKN1_0199	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
FOKN1_0200	COG0706	membrane insertase activity
FOKN1_0201	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
FOKN1_0202	COG0582	viral genome integration into host DNA
FOKN1_0207	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FOKN1_0217	COG0714	Associated with various cellular activities
FOKN1_0220	COG0445	tRNA wobble uridine modification
FOKN1_0221	COG0357	Ribosomal RNA small subunit methyltransferase G
FOKN1_0222	COG1192	Involved in chromosome partitioning
FOKN1_0223	COG1475	DNA binding
FOKN1_0225	COG0356	it plays a direct role in the translocation of protons across the membrane
FOKN1_0227	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
FOKN1_0228	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
FOKN1_0229	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
FOKN1_0230	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
FOKN1_0231	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
FOKN1_0232	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FOKN1_0233	COG1047	Peptidyl-prolyl cis-trans
FOKN1_0234	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
FOKN1_0235	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOKN1_0236	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FOKN1_0247	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FOKN1_0253	COG1846	Transcriptional regulator
FOKN1_0255	COG1509	lysine 2,3-aminomutase activity
FOKN1_0256	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOKN1_0257	COG0438	transferase activity, transferring glycosyl groups
FOKN1_0258	COG0438	transferase activity, transferring glycosyl groups
FOKN1_0263	COG0488	(ABC) transporter
FOKN1_0264	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FOKN1_0266	COG4206	TonB-dependent receptor
FOKN1_0269	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FOKN1_0273	COG1773	rubredoxin
FOKN1_0275	COG3706	GGDEF domain
FOKN1_0276	COG0009	L-threonylcarbamoyladenylate synthase
FOKN1_0278	COG0004	ammonium transporteR
FOKN1_0279	COG0347	Belongs to the P(II) protein family
FOKN1_0281	COG0606	chelatase, subunit chli
FOKN1_0283	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
FOKN1_0284	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
FOKN1_0285	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FOKN1_0286	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOKN1_0287	COG0640	Transcriptional regulator
FOKN1_0289	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FOKN1_0290	COG4942	peptidase
FOKN1_0291	COG0793	Belongs to the peptidase S41A family
FOKN1_0292	COG2861	carbohydrate metabolic process
FOKN1_0294	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FOKN1_0298	COG0730	response to heat
FOKN1_0300	COG0583	DNA-binding transcription factor activity
FOKN1_0302	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
FOKN1_0306	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FOKN1_0307	COG3706	GGDEF domain
FOKN1_0313	COG1943	Transposase
FOKN1_0316	COG3072	Adenylate cyclase
FOKN1_0320	COG5001	Diguanylate cyclase
FOKN1_0320	COG5002	protein histidine kinase activity
FOKN1_0321	COG0165	Argininosuccinate lyase
FOKN1_0322	COG2972	Histidine kinase
FOKN1_0322	COG0745	RESPONSE REGULATOR receiver
FOKN1_0325	COG0181	hydroxymethylbilane synthase activity
FOKN1_0329	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FOKN1_0329	COG0543	2 iron, 2 sulfur cluster binding
FOKN1_0331	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
FOKN1_0336	COG1490	D-aminoacyl-tRNA deacylase activity
FOKN1_0338	COG2210	Belongs to the sulfur carrier protein TusA family
FOKN1_0340	COG0037	tRNA processing
FOKN1_0342	COG3189	MarR family transcriptional regulator
FOKN1_0348	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FOKN1_0349	COG0569	domain protein
FOKN1_0350	COG2204	response regulator
FOKN1_0351	COG5000	phosphorelay sensor kinase activity
FOKN1_0354	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
FOKN1_0355	COG0242	peptide deformylase activity
FOKN1_0357	COG0758	DNA mediated transformation
FOKN1_0358	COG2922	Belongs to the Smg family
FOKN1_0364	COG1611	Belongs to the LOG family
FOKN1_0366	COG0218	Necessary for normal cell division and for the maintenance of normal septation
FOKN1_0368	COG1333	cytochrome c biogenesis protein
FOKN1_0369	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
FOKN1_0373	COG3706	GGDEF domain
FOKN1_0374	COG0435	Glutathione S-transferase
FOKN1_0378	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOKN1_0379	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
FOKN1_0380	COG0140	phosphoribosyl-ATP diphosphatase activity
FOKN1_0381	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FOKN1_0382	COG0107	imidazoleglycerol-phosphate synthase activity
FOKN1_0383	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
FOKN1_0384	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FOKN1_0385	COG0131	Imidazoleglycerol-phosphate dehydratase
FOKN1_0386	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOKN1_0387	COG3278	Belongs to the heme-copper respiratory oxidase family
FOKN1_0390	COG2010	Cytochrome c
FOKN1_0394	COG0842	Transport permease protein
FOKN1_0395	COG1131	(ABC) transporter
FOKN1_0397	COG0745	RESPONSE REGULATOR receiver
FOKN1_0402	COG0745	RESPONSE REGULATOR receiver
FOKN1_0404	COG0521	Mo-molybdopterin cofactor biosynthetic process
FOKN1_0406	COG0189	ligase activity
FOKN1_0411	COG3706	GGDEF domain
FOKN1_0414	COG2827	Endonuclease containing a URI domain
FOKN1_0416	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOKN1_0419	COG1278	Cold shock
FOKN1_0424	COG3901	Regulator of nitric oxide reductase transcription
FOKN1_0424	COG0348	domain, Protein
FOKN1_0425	COG4263	nitrous-oxide reductase activity
FOKN1_0431	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
FOKN1_0432	COG5642	Protein of unknown function (DUF2384)
FOKN1_0434	COG1280	lysine exporter protein (LysE YggA)
FOKN1_0435	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FOKN1_0436	COG0358	DNA primase activity
FOKN1_0437	COG1610	YqeY-like protein
FOKN1_0438	COG0828	Belongs to the bacterial ribosomal protein bS21 family
FOKN1_0440	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
FOKN1_0441	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FOKN1_0444	COG1968	undecaprenyl-diphosphatase activity
FOKN1_0446	COG0617	tRNA 3'-terminal CCA addition
FOKN1_0448	COG0651	ATP synthesis coupled electron transport
FOKN1_0449	COG0651	ATP synthesis coupled electron transport
FOKN1_0450	COG0651	ATP synthesis coupled electron transport
FOKN1_0453	COG1320	monovalent cation:proton antiporter activity
FOKN1_0456	COG1196	nuclear chromosome segregation
FOKN1_0456	COG0741	lytic transglycosylase activity
FOKN1_0456	COG0739	heme binding
FOKN1_0457	COG1012	belongs to the aldehyde dehydrogenase family
FOKN1_0458	COG0730	response to heat
FOKN1_0460	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOKN1_0460	COG1648	precorrin-2 dehydrogenase activity
FOKN1_0471	COG2010	Cytochrome c
FOKN1_0473	COG1845	cytochrome c oxidase, subunit III
FOKN1_0480	COG1242	4 iron, 4 sulfur cluster binding
FOKN1_0487	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
FOKN1_0488	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
FOKN1_0489	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FOKN1_0490	COG3302	dmso reductase anchor subunit
FOKN1_0491	COG0437	4 iron, 4 sulfur cluster binding
FOKN1_0492	COG0243	molybdopterin cofactor binding
FOKN1_0493	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FOKN1_0498	COG2813	Specifically methylates the guanine in position
FOKN1_0503	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FOKN1_0504	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FOKN1_0505	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
FOKN1_0509	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOKN1_0515	COG2217	Heavy metal translocating P-type atpase
FOKN1_0516	COG0697	spore germination
FOKN1_0521	COG2132	Multicopper oxidase
FOKN1_0526	COG2239	Acts as a magnesium transporter
FOKN1_0528	COG2258	MOSC domain
FOKN1_0529	COG2217	Heavy metal translocating P-type atpase
FOKN1_0538	COG3852	Histidine kinase
FOKN1_0539	COG2204	response regulator
FOKN1_0546	COG1612	heme a metabolic process
FOKN1_0548	COG0667	Aldo Keto reductase
FOKN1_0550	COG3954	Phosphoribulokinase
FOKN1_0551	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FOKN1_0552	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
FOKN1_0552	COG3264	Mechanosensitive ion channel
FOKN1_0553	COG0598	Magnesium transport protein CorA
FOKN1_0554	COG2022	thiamine diphosphate biosynthetic process
FOKN1_0556	COG1022	Amp-dependent synthetase and ligase
FOKN1_0564	COG2982	Protein involved in outer membrane biogenesis
FOKN1_0565	COG1194	a g-specific adenine glycosylase
FOKN1_0566	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
FOKN1_0573	COG2046	Belongs to the sulfate adenylyltransferase family
FOKN1_0573	COG0529	Catalyzes the synthesis of activated sulfate
FOKN1_0585	COG0297	glycogen (starch) synthase activity
FOKN1_0588	COG0297	glycogen (starch) synthase activity
FOKN1_0590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOKN1_0592	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FOKN1_0595	COG2205	protein histidine kinase activity
FOKN1_0595	COG2198	Histidine kinase
FOKN1_0595	COG0784	Response regulator, receiver
FOKN1_0596	COG2204	response regulator
FOKN1_0597	COG2827	Endonuclease containing a URI domain
FOKN1_0598	COG4232	protein-disulfide reductase activity
FOKN1_0599	COG1324	tolerance protein
FOKN1_0601	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
FOKN1_0602	COG0459	protein refolding
FOKN1_0604	COG1595	DNA-templated transcription, initiation
FOKN1_0606	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FOKN1_0616	COG1560	Kdo2-lipid A biosynthetic process
FOKN1_0617	COG1519	Transferase
FOKN1_0619	COG1538	Outer membrane efflux protein
FOKN1_0620	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOKN1_0621	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOKN1_0624	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
FOKN1_0627	COG1192	Involved in chromosome partitioning
FOKN1_0630	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOKN1_0632	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOKN1_0639	COG0425	Belongs to the sulfur carrier protein TusA family
FOKN1_0642	COG1970	mechanosensitive ion channel activity
FOKN1_0653	COG2329	Antibiotic biosynthesis monooxygenase
FOKN1_0659	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOKN1_0665	COG0433	COG0433 Predicted ATPase
FOKN1_0686	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOKN1_0688	COG4175	Glycine betaine
FOKN1_0689	COG4176	ABC-type proline glycine betaine transport system permease component
FOKN1_0694	COG1902	pentaerythritol trinitrate reductase activity
FOKN1_0698	COG2985	domain, Protein
FOKN1_0698	COG0490	domain, Protein
FOKN1_0701	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOKN1_0702	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOKN1_0702	COG1136	(ABC) transporter
FOKN1_0706	COG0513	Belongs to the DEAD box helicase family
FOKN1_0707	COG2010	Cytochrome c
FOKN1_0708	COG1850	ribulose-bisphosphate carboxylase activity
FOKN1_0709	COG4451	ribulose bisphosphate carboxylase, small
FOKN1_0713	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
FOKN1_0721	COG0659	secondary active sulfate transmembrane transporter activity
FOKN1_0722	COG0583	DNA-binding transcription factor activity
FOKN1_0725	COG2863	cytochrome
FOKN1_0726	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOKN1_0727	COG4572	Cation transport regulator
FOKN1_0728	COG3360	Dodecin
FOKN1_0729	COG1403	HNH endonuclease
FOKN1_0736	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FOKN1_0738	COG1187	pseudouridine synthase activity
FOKN1_0740	COG3706	GGDEF domain
FOKN1_0741	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
FOKN1_0747	COG1639	'signal transduction protein
FOKN1_0753	COG0315	cyclic pyranopterin monophosphate synthase activity
FOKN1_0754	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
FOKN1_0756	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FOKN1_0757	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
FOKN1_0758	COG0205	6-phosphofructokinase activity
FOKN1_0759	COG0563	adenylate kinase activity
FOKN1_0760	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FOKN1_0762	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOKN1_0765	COG0586	Pfam SNARE associated Golgi protein
FOKN1_0766	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
FOKN1_0767	COG0352	thiamine-phosphate diphosphorylase activity
FOKN1_0779	COG1011	Hydrolase
FOKN1_0780	COG0494	nUDIX hydrolase
FOKN1_0781	COG1218	3'(2'),5'-bisphosphate nucleotidase
FOKN1_0783	COG3267	Type II secretory pathway component ExeA
FOKN1_0783	COG3409	Peptidoglycan-binding domain 1 protein
FOKN1_0784	COG0489	protein tyrosine kinase activity
FOKN1_0791	COG0457	Tetratricopeptide repeat
FOKN1_0795	COG0457	Tetratricopeptide repeat
FOKN1_0797	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOKN1_0798	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FOKN1_0799	COG0511	ligase activity, forming carbon-carbon bonds
FOKN1_0801	COG0439	Biotin carboxylase
FOKN1_0802	COG2264	protein methyltransferase activity
FOKN1_0805	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FOKN1_0806	COG0138	bifunctional purine biosynthesis protein purh
FOKN1_0807	COG0151	Belongs to the GarS family
FOKN1_0811	COG3031	protein transport across the cell outer membrane
FOKN1_0818	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOKN1_0819	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOKN1_0819	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
FOKN1_0822	COG0189	ligase activity
FOKN1_0823	COG0840	transmembrane signaling receptor activity
FOKN1_0824	COG0129	dihydroxy-acid dehydratase activity
FOKN1_0828	COG0406	alpha-ribazole phosphatase activity
FOKN1_0830	COG0708	Exodeoxyribonuclease III
FOKN1_0836	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOKN1_0838	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FOKN1_0841	COG4191	Histidine kinase
FOKN1_0841	COG2205	protein histidine kinase activity
FOKN1_0841	COG0745	RESPONSE REGULATOR receiver
FOKN1_0842	COG4772	TonB-dependent receptor
FOKN1_0846	COG0494	nUDIX hydrolase
FOKN1_0849	COG1959	2 iron, 2 sulfur cluster binding
FOKN1_0851	COG2020	methyltransferase activity
FOKN1_0852	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FOKN1_0854	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOKN1_0855	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FOKN1_0863	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FOKN1_0864	COG1840	ABC-type Fe3 transport system, periplasmic component
FOKN1_0865	COG1178	ABC-type Fe3 transport system permease component
FOKN1_0866	COG3842	ATPase activity
FOKN1_0867	COG1047	Peptidyl-prolyl cis-trans
FOKN1_0868	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOKN1_0878	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOKN1_0882	COG0484	heat shock protein binding
FOKN1_0888	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FOKN1_0889	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
FOKN1_0890	COG1959	2 iron, 2 sulfur cluster binding
FOKN1_0894	COG1704	LemA family
FOKN1_0896	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOKN1_0897	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FOKN1_0899	COG0142	geranyltranstransferase activity
FOKN1_0900	COG0261	This protein binds to 23S rRNA in the presence of protein L20
FOKN1_0902	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FOKN1_0903	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
FOKN1_0904	COG0268	Binds directly to 16S ribosomal RNA
FOKN1_0906	COG0196	riboflavin kinase activity
FOKN1_0907	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FOKN1_0908	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
FOKN1_0910	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
FOKN1_0923	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FOKN1_0927	COG1335	isochorismatase
FOKN1_0929	COG0540	Belongs to the ATCase OTCase family
FOKN1_0930	COG0367	asparagine synthase
FOKN1_0934	COG3604	Transcriptional regulator
FOKN1_0935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FOKN1_0936	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FOKN1_0937	COG1116	anion transmembrane transporter activity
FOKN1_0938	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
FOKN1_0945	COG3706	GGDEF domain
FOKN1_0945	COG0745	RESPONSE REGULATOR receiver
FOKN1_0947	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
FOKN1_0949	COG1115	amino acid carrier protein
FOKN1_0950	COG3577	Aspartyl protease
FOKN1_0955	COG0745	RESPONSE REGULATOR receiver
FOKN1_0959	COG0248	Ppx GppA phosphatase
FOKN1_0960	COG2259	Doxx family
FOKN1_0962	COG3220	belongs to the UPF0276 family
FOKN1_0964	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FOKN1_0965	COG5002	protein histidine kinase activity
FOKN1_0965	COG5001	Diguanylate cyclase
FOKN1_0966	COG4660	Part of a membrane complex involved in electron transport
FOKN1_0967	COG4659	FMN binding
FOKN1_0968	COG4658	electron transport chain
FOKN1_0970	COG2878	Part of a membrane complex involved in electron transport
FOKN1_0971	COG4657	Part of a membrane complex involved in electron transport
FOKN1_0972	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOKN1_0972	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FOKN1_0973	COG0489	protein tyrosine kinase activity
FOKN1_0974	COG0717	Belongs to the dCTP deaminase family
FOKN1_0976	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FOKN1_0977	COG0297	glycogen (starch) synthase activity
FOKN1_0978	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
FOKN1_0979	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
FOKN1_0980	COG0166	Belongs to the GPI family
FOKN1_0982	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
FOKN1_0983	COG1702	phosphate starvation-inducible protein PhoH
FOKN1_0984	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
FOKN1_0985	COG4535	Mg2 and Co2 transporter CorC
FOKN1_0986	COG0815	Transfers the fatty acyl group on membrane lipoproteins
FOKN1_0989	COG0495	leucyl-tRNA aminoacylation
FOKN1_0991	COG1466	dna polymerase III delta subunit
FOKN1_0992	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
FOKN1_0993	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FOKN1_0995	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
FOKN1_0997	COG1530	ribonuclease E activity
FOKN1_0998	COG3164	Protein of unknown function
FOKN1_1000	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOKN1_1001	COG0312	modulator of DNA gyrase
FOKN1_1008	COG3028	Belongs to the UPF0307 family
FOKN1_1010	COG0312	modulator of DNA gyrase
FOKN1_1012	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
FOKN1_1013	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOKN1_1015	COG2239	Acts as a magnesium transporter
FOKN1_1016	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FOKN1_1017	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FOKN1_1019	COG1660	Displays ATPase and GTPase activities
FOKN1_1023	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
FOKN1_1024	COG1137	ATPase activity
FOKN1_1025	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FOKN1_1027	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FOKN1_1032	COG1127	ABC transporter
FOKN1_1033	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOKN1_1034	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FOKN1_1035	COG3113	response to antibiotic
FOKN1_1036	COG0271	Belongs to the BolA IbaG family
FOKN1_1037	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FOKN1_1038	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FOKN1_1039	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FOKN1_1040	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOKN1_1042	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FOKN1_1043	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
FOKN1_1045	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOKN1_1046	COG0628	permease
FOKN1_1050	COG1393	Belongs to the ArsC family
FOKN1_1054	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOKN1_1057	COG1566	PFAM secretion protein HlyD family protein
FOKN1_1058	COG1254	Belongs to the acylphosphatase family
FOKN1_1062	COG3026	antisigma factor binding
FOKN1_1064	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOKN1_1066	COG0481	GTPase activity
FOKN1_1067	COG0681	Belongs to the peptidase S26 family
FOKN1_1069	COG0571	ribonuclease III activity
FOKN1_1070	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FOKN1_1071	COG1381	Involved in DNA repair and RecF pathway recombination
FOKN1_1072	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FOKN1_1073	COG0736	holo-[acyl-carrier-protein] synthase activity
FOKN1_1074	COG5002	protein histidine kinase activity
FOKN1_1074	COG2205	protein histidine kinase activity
FOKN1_1074	COG0784	Response regulator, receiver
FOKN1_1081	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
FOKN1_1083	COG3002	Belongs to the UPF0753 family
FOKN1_1085	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOKN1_1086	COG0741	lytic transglycosylase activity
FOKN1_1086	COG1196	nuclear chromosome segregation
FOKN1_1086	COG0739	heme binding
FOKN1_1087	COG0494	nUDIX hydrolase
FOKN1_1089	COG0217	transcriptional regulatory protein
FOKN1_1090	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
FOKN1_1091	COG0632	four-way junction helicase activity
FOKN1_1092	COG2255	four-way junction helicase activity
FOKN1_1093	COG0824	Thioesterase
FOKN1_1097	COG0823	Involved in the tonB-independent uptake of proteins
FOKN1_1099	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
FOKN1_1100	COG0602	queuosine metabolic process
FOKN1_1101	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FOKN1_1105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOKN1_1110	COG1294	oxidase, subunit
FOKN1_1120	COG0588	phosphoglycerate mutase activity
FOKN1_1121	COG0783	Belongs to the Dps family
FOKN1_1127	COG4771	TonB-dependent receptor
FOKN1_1129	COG0748	coenzyme F420 binding
FOKN1_1130	COG4558	Periplasmic binding protein
FOKN1_1131	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FOKN1_1132	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
FOKN1_1135	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOKN1_1137	COG0583	DNA-binding transcription factor activity
FOKN1_1138	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
FOKN1_1141	COG4772	TonB-dependent receptor
FOKN1_1145	COG4771	TonB-dependent receptor
FOKN1_1147	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOKN1_1148	COG0737	Belongs to the 5'-nucleotidase family
FOKN1_1149	COG3258	Cytochrome c
FOKN1_1153	COG4783	chaperone-mediated protein folding
FOKN1_1154	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FOKN1_1155	COG0425	Belongs to the sulfur carrier protein TusA family
FOKN1_1156	COG2067	long-chain fatty acid transport protein
FOKN1_1160	COG0840	transmembrane signaling receptor activity
FOKN1_1163	COG0583	DNA-binding transcription factor activity
FOKN1_1166	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
FOKN1_1167	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOKN1_1168	COG2716	regulation of RNA biosynthetic process
FOKN1_1170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FOKN1_1171	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
FOKN1_1172	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
FOKN1_1174	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
FOKN1_1176	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
FOKN1_1179	COG0488	(ABC) transporter
FOKN1_1181	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
FOKN1_1182	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FOKN1_1183	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOKN1_1183	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FOKN1_1186	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
FOKN1_1189	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FOKN1_1191	COG1469	GTP cyclohydrolase I activity
FOKN1_1192	COG0720	synthase
FOKN1_1193	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FOKN1_1194	COG0142	geranyltranstransferase activity
FOKN1_1195	COG1722	exodeoxyribonuclease VII activity
FOKN1_1201	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FOKN1_1202	COG1592	Rubrerythrin
FOKN1_1209	COG3209	COG3209 Rhs family protein
FOKN1_1213	COG0501	Belongs to the peptidase M48B family
FOKN1_1215	COG5002	protein histidine kinase activity
FOKN1_1215	COG5001	Diguanylate cyclase
FOKN1_1218	COG1509	lysine 2,3-aminomutase activity
FOKN1_1219	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
FOKN1_1220	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FOKN1_1221	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FOKN1_1222	COG1127	ABC transporter
FOKN1_1227	COG1959	2 iron, 2 sulfur cluster binding
FOKN1_1229	COG0105	UTP biosynthetic process
FOKN1_1230	COG0820	rRNA (adenine-C2-)-methyltransferase activity
FOKN1_1233	COG0124	histidyl-tRNA synthetase
FOKN1_1236	COG1160	GTP binding
FOKN1_1237	COG0659	secondary active sulfate transmembrane transporter activity
FOKN1_1239	COG4181	ATPase activity
FOKN1_1241	COG0674	pyruvate-flavodoxin oxidoreductase activity
FOKN1_1241	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FOKN1_1241	COG1013	pyruvate-flavodoxin oxidoreductase activity
FOKN1_1241	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
FOKN1_1242	COG0167	dihydroorotate dehydrogenase activity
FOKN1_1245	COG1570	exodeoxyribonuclease VII activity
FOKN1_1247	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FOKN1_1247	COG0519	Catalyzes the synthesis of GMP from XMP
FOKN1_1248	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOKN1_1253	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOKN1_1255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FOKN1_1258	COG0590	tRNA wobble adenosine to inosine editing
FOKN1_1259	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOKN1_1261	COG0516	GMP reductase activity
FOKN1_1261	COG0517	IMP dehydrogenase activity
FOKN1_1262	COG2920	part of a sulfur-relay system
FOKN1_1263	COG0583	DNA-binding transcription factor activity
FOKN1_1268	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOKN1_1269	COG0156	8-amino-7-oxononanoate synthase activity
FOKN1_1273	COG1132	(ABC) transporter
FOKN1_1278	COG0456	acetyltransferase
FOKN1_1286	COG1597	lipid kinase activity
FOKN1_1292	COG0848	biopolymer transport protein
FOKN1_1293	COG0848	biopolymer transport protein
FOKN1_1294	COG0811	peptide transport
FOKN1_1302	COG3258	Cytochrome c
FOKN1_1303	COG2863	cytochrome
FOKN1_1305	COG0516	GMP reductase activity
FOKN1_1305	COG0517	IMP dehydrogenase activity
FOKN1_1306	COG2221	Nitrite and sulphite reductase 4Fe-4S
FOKN1_1307	COG2221	Nitrite and sulphite reductase 4Fe-4S
FOKN1_1308	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOKN1_1338	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOKN1_1345	COG2204	response regulator
FOKN1_1346	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
FOKN1_1348	COG1322	Protein conserved in bacteria
FOKN1_1349	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FOKN1_1350	COG0732	type I restriction modification DNA specificity domain
FOKN1_1356	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
FOKN1_1360	COG2356	endonuclease I
FOKN1_1404	COG2308	Evidence 4 Homologs of previously reported genes of
FOKN1_1406	COG1051	belongs to the nudix hydrolase family
FOKN1_1408	COG1131	(ABC) transporter
FOKN1_1410	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOKN1_1414	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FOKN1_1417	COG0415	Belongs to the DNA photolyase family
FOKN1_1419	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOKN1_1424	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FOKN1_1424	COG2198	Histidine kinase
FOKN1_1424	COG2205	protein histidine kinase activity
FOKN1_1424	COG0784	Response regulator, receiver
FOKN1_1428	COG1408	metallophosphoesterase
FOKN1_1432	COG1366	Belongs to the anti-sigma-factor antagonist family
FOKN1_1434	COG1127	ABC transporter
FOKN1_1438	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FOKN1_1447	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
FOKN1_1448	COG0784	Response regulator, receiver
FOKN1_1448	COG0835	chemotaxis
FOKN1_1449	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
FOKN1_1451	COG1558	bacterial-type flagellum-dependent cell motility
FOKN1_1452	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
FOKN1_1455	COG4786	Flagellar basal body rod
FOKN1_1456	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
FOKN1_1457	COG1706	bacterial-type flagellum-dependent cell motility
FOKN1_1458	COG3951	Flagellar rod assembly protein muramidase FlgJ
FOKN1_1458	COG1705	Flagellar rod assembly protein muramidase FlgJ
FOKN1_1459	COG1256	bacterial-type flagellum assembly
FOKN1_1461	COG5001	Diguanylate cyclase
FOKN1_1461	COG5002	protein histidine kinase activity
FOKN1_1464	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
FOKN1_1468	COG3604	Transcriptional regulator
FOKN1_1469	COG3852	Histidine kinase
FOKN1_1470	COG2204	response regulator
FOKN1_1471	COG1677	Flagellar hook-basal body complex protein FliE
FOKN1_1474	COG1317	bacterial-type flagellum organization
FOKN1_1482	COG0513	Belongs to the DEAD box helicase family
FOKN1_1484	COG3122	Protein conserved in bacteria
FOKN1_1490	COG1987	bacterial-type flagellum assembly
FOKN1_1493	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOKN1_1495	COG0455	bacterial-type flagellum organization
FOKN1_1498	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
FOKN1_1499	COG2198	Histidine kinase
FOKN1_1499	COG0643	Histidine kinase
FOKN1_1500	COG2201	protein-glutamate methylesterase activity
FOKN1_1501	COG1192	Involved in chromosome partitioning
FOKN1_1504	COG0835	chemotaxis
FOKN1_1508	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
FOKN1_1514	COG2078	PFAM AMMECR1 domain protein
FOKN1_1514	COG3885	ferrous iron binding
FOKN1_1515	COG1355	regulation of microtubule-based process
FOKN1_1519	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
FOKN1_1520	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOKN1_1525	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
FOKN1_1526	COG0343	queuine tRNA-ribosyltransferase activity
FOKN1_1527	COG1862	Preprotein translocase
FOKN1_1528	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOKN1_1529	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FOKN1_1534	COG0688	phosphatidylethanolamine metabolic process
FOKN1_1540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
FOKN1_1543	COG1830	Aldolase
FOKN1_1544	COG5001	Diguanylate cyclase
FOKN1_1544	COG5002	protein histidine kinase activity
FOKN1_1547	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
FOKN1_1549	COG0473	3-isopropylmalate dehydrogenase activity
FOKN1_1550	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
FOKN1_1556	COG0101	tRNA pseudouridine synthase activity
FOKN1_1557	COG0135	phosphoribosylanthranilate isomerase activity
FOKN1_1558	COG0133	tryptophan synthase activity
FOKN1_1559	COG0159	tryptophan synthase activity
FOKN1_1560	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
FOKN1_1561	COG0285	dihydrofolate synthase activity
FOKN1_1567	COG2379	hydroxypyruvate reductase
FOKN1_1568	COG2833	Protein of unknown function (DUF455)
FOKN1_1571	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOKN1_1572	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FOKN1_1573	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOKN1_1574	COG0215	cysteine-tRNA ligase activity
FOKN1_1576	COG5002	protein histidine kinase activity
FOKN1_1576	COG5001	Diguanylate cyclase
FOKN1_1577	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
FOKN1_1583	COG0544	peptidyl-prolyl cis-trans isomerase activity
FOKN1_1584	COG0740	serine-type endopeptidase activity
FOKN1_1585	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
FOKN1_1586	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOKN1_1590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOKN1_1591	COG1301	dicarboxylic acid transport
FOKN1_1594	COG0601	transmembrane transport
FOKN1_1595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FOKN1_1596	COG4172	Belongs to the ABC transporter superfamily
FOKN1_1597	COG1404	Belongs to the peptidase S8 family
FOKN1_1598	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FOKN1_1600	COG0429	hydrolase of the alpha beta-hydrolase fold
FOKN1_1605	COG1278	Cold shock
FOKN1_1609	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FOKN1_1610	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
FOKN1_1611	COG0514	ATP-dependent DNA helicase (RecQ)
FOKN1_1612	COG0514	ATP-dependent DNA helicase (RecQ)
FOKN1_1620	COG1216	Glycosyl transferase, family 2
FOKN1_1623	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FOKN1_1625	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOKN1_1629	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FOKN1_1633	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
FOKN1_1640	COG0640	Transcriptional regulator
FOKN1_1642	COG0398	Pfam SNARE associated Golgi protein
FOKN1_1646	COG2226	methyltransferase
FOKN1_1649	COG0306	phosphate transporter
FOKN1_1653	COG0450	alkyl hydroperoxide reductase
FOKN1_1659	COG3706	GGDEF domain
FOKN1_1660	COG2925	Exonuclease
FOKN1_1665	COG1047	Peptidyl-prolyl cis-trans
FOKN1_1682	COG0582	viral genome integration into host DNA
FOKN1_1683	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
FOKN1_1684	COG0733	neurotransmitter:sodium symporter activity
FOKN1_1686	COG2914	Belongs to the UPF0125 (RnfH) family
FOKN1_1688	COG0735	belongs to the Fur family
FOKN1_1689	COG0497	DNA recombination
FOKN1_1690	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FOKN1_1691	COG1420	regulation of RNA biosynthetic process
FOKN1_1692	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FOKN1_1693	COG0443	Heat shock 70 kDa protein
FOKN1_1694	COG0484	heat shock protein binding
FOKN1_1695	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FOKN1_1696	COG0505	Belongs to the CarA family
FOKN1_1697	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
FOKN1_1698	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FOKN1_1701	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
FOKN1_1702	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FOKN1_1703	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FOKN1_1704	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FOKN1_1705	COG0149	triose-phosphate isomerase activity
FOKN1_1708	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOKN1_1709	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOKN1_1710	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOKN1_1711	COG0649	NAD binding
FOKN1_1714	COG1034	ATP synthesis coupled electron transport
FOKN1_1715	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
FOKN1_1716	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FOKN1_1718	COG0713	ATP synthesis coupled electron transport
FOKN1_1721	COG1007	ATP synthesis coupled electron transport
FOKN1_1726	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
FOKN1_1727	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FOKN1_1730	COG0563	adenylate kinase activity
FOKN1_1731	COG0729	surface antigen
FOKN1_1732	COG2911	Protein conserved in bacteria
FOKN1_1736	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FOKN1_1739	COG0789	Transcriptional regulator
FOKN1_1740	COG4221	oxidoreductase activity
FOKN1_1743	COG0471	metal ion transport
FOKN1_1743	COG3273	potassium ion transport
FOKN1_1746	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FOKN1_1748	COG0779	Required for maturation of 30S ribosomal subunits
FOKN1_1749	COG2251	uridine kinase activity
FOKN1_1749	COG0195	Participates in both transcription termination and antitermination
FOKN1_1750	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
FOKN1_1751	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
FOKN1_1752	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FOKN1_1753	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
FOKN1_1754	COG1185	polyribonucleotide nucleotidyltransferase activity
FOKN1_1758	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FOKN1_1760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOKN1_1761	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FOKN1_1763	COG0436	Aminotransferase
FOKN1_1765	COG1070	Carbohydrate kinase
FOKN1_1766	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
FOKN1_1767	COG1196	nuclear chromosome segregation
FOKN1_1769	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FOKN1_1772	COG1376	ErfK ybiS ycfS ynhG family protein
FOKN1_1775	COG0579	oxidoreductase
FOKN1_1776	COG0247	lactate metabolic process
FOKN1_1777	COG0277	FAD linked oxidase domain protein
FOKN1_1778	COG0277	FAD linked oxidase domain protein
FOKN1_1779	COG0500	methyltransferase
FOKN1_1782	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FOKN1_1785	COG1199	ATP-dependent helicase activity
FOKN1_1790	COG2210	Belongs to the sulfur carrier protein TusA family
FOKN1_1794	COG0446	pyridine nucleotide-disulphide oxidoreductase
FOKN1_1798	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
FOKN1_1799	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FOKN1_1799	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
FOKN1_1800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOKN1_1801	COG2957	Belongs to the agmatine deiminase family
FOKN1_1804	COG4591	ABC-type transport system involved in lipoprotein release permease component
FOKN1_1805	COG1136	(ABC) transporter
FOKN1_1807	COG0658	competence protein
FOKN1_1807	COG2333	competence protein COMEC
FOKN1_1808	COG0811	peptide transport
FOKN1_1809	COG0848	biopolymer transport protein
FOKN1_1810	COG1132	(ABC) transporter
FOKN1_1811	COG1663	tetraacyldisaccharide 4'-kinase activity
FOKN1_1812	COG2835	tetraacyldisaccharide 4'-kinase activity
FOKN1_1813	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
FOKN1_1818	COG2203	Gaf domain
FOKN1_1818	COG4251	negative regulation of phosphorylation
FOKN1_1818	COG5001	Diguanylate cyclase
FOKN1_1818	COG3706	GGDEF domain
FOKN1_1821	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOKN1_1822	COG1530	ribonuclease E activity
FOKN1_1823	COG0564	pseudouridine synthase activity
FOKN1_1824	COG0546	phosphoglycolate phosphatase activity
FOKN1_1827	COG0424	maF-like protein
FOKN1_1828	COG5016	pyruvate
FOKN1_1828	COG0511	ligase activity, forming carbon-carbon bonds
FOKN1_1830	COG0439	Biotin carboxylase
FOKN1_1832	COG0333	Belongs to the bacterial ribosomal protein bL32 family
FOKN1_1833	COG0416	fatty acid biosynthetic process
FOKN1_1834	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
FOKN1_1835	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FOKN1_1836	COG1028	Short-chain dehydrogenase reductase Sdr
FOKN1_1837	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FOKN1_1838	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FOKN1_1839	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FOKN1_1840	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FOKN1_1841	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FOKN1_1843	COG0372	Belongs to the citrate synthase family
FOKN1_1845	COG3245	cytochrome
FOKN1_1846	COG1187	pseudouridine synthase activity
FOKN1_1847	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
FOKN1_1850	COG0084	hydrolase, TatD family'
FOKN1_1852	COG1607	acyl-coa hydrolase
FOKN1_1853	COG1022	Amp-dependent synthetase and ligase
FOKN1_1854	COG1024	Enoyl-CoA hydratase
FOKN1_1854	COG1250	3-hydroxyacyl-CoA dehydrogenase
FOKN1_1862	COG3276	selenocysteine insertion sequence binding
FOKN1_1870	COG3038	cytochrome b561
FOKN1_1872	COG4067	protein conserved in archaea
FOKN1_1872	COG0189	ligase activity
FOKN1_1873	COG0189	ligase activity
FOKN1_1877	COG2046	Belongs to the sulfate adenylyltransferase family
FOKN1_1879	COG3174	membrane
FOKN1_1881	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOKN1_1883	COG0668	transmembrane transport
FOKN1_1887	COG2020	methyltransferase activity
FOKN1_1891	COG3588	fructose-bisphosphate aldolase
FOKN1_1896	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FOKN1_1897	COG0322	excinuclease ABC activity
FOKN1_1898	COG1573	uracil-dna glycosylase
FOKN1_1906	COG2204	response regulator
FOKN1_1922	COG0670	Belongs to the BI1 family
FOKN1_1929	COG1404	Belongs to the peptidase S8 family
FOKN1_1934	COG0456	acetyltransferase
FOKN1_1935	COG0730	response to heat
FOKN1_1936	COG3706	GGDEF domain
FOKN1_1939	COG3128	pkhd-type hydroxylase
FOKN1_1945	COG2221	Nitrite and sulphite reductase 4Fe-4S
FOKN1_1946	COG2221	Nitrite and sulphite reductase 4Fe-4S
FOKN1_1947	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FOKN1_1948	COG2923	Belongs to the DsrF TusC family
FOKN1_1950	COG2920	part of a sulfur-relay system
FOKN1_1958	COG1797	cobyrinic acid a,c-diamide synthase activity
FOKN1_1960	COG3850	Histidine kinase
FOKN1_1961	COG2197	response regulator
FOKN1_1964	COG1252	NADH dehydrogenase
FOKN1_1967	COG1648	precorrin-2 dehydrogenase activity
FOKN1_1967	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FOKN1_1969	COG0308	aminopeptidase N
FOKN1_1973	COG3706	GGDEF domain
FOKN1_1975	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
FOKN1_1977	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FOKN1_1978	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FOKN1_1979	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOKN1_1980	COG1674	ftsk spoiiie
FOKN1_1981	COG0686	Belongs to the AlaDH PNT family
FOKN1_1982	COG0492	ferredoxin-NADP+ reductase activity
FOKN1_1984	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FOKN1_1985	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
FOKN1_1986	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
FOKN1_1987	COG0542	response to heat
FOKN1_1988	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FOKN1_1989	COG1278	Cold shock
FOKN1_1994	COG2915	High frequency lysogenization protein hflD homolog
FOKN1_1995	COG0745	RESPONSE REGULATOR receiver
FOKN1_1995	COG3706	GGDEF domain
FOKN1_1996	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FOKN1_2003	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
FOKN1_2010	COG2239	Acts as a magnesium transporter
FOKN1_2013	COG0589	response to stress
FOKN1_2017	COG1269	ATP hydrolysis coupled proton transport
FOKN1_2021	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
FOKN1_2022	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
FOKN1_2027	COG3263	regulation of cellular component size
FOKN1_2029	COG3108	Peptidase M15
FOKN1_2031	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FOKN1_2033	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FOKN1_2035	COG0436	Aminotransferase
FOKN1_2039	COG1238	metal cluster binding
FOKN1_2040	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOKN1_2041	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FOKN1_2042	COG1193	negative regulation of DNA recombination
FOKN1_2043	COG0585	pseudouridine synthase activity
FOKN1_2050	COG1943	Transposase
FOKN1_2052	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
FOKN1_2053	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
FOKN1_2054	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
FOKN1_2055	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FOKN1_2056	COG0148	phosphopyruvate hydratase activity
FOKN1_2057	COG2877	3-deoxy-8-phosphooctulonate synthase activity
FOKN1_2058	COG0504	CTP synthase activity
FOKN1_2059	COG0037	tRNA processing
FOKN1_2060	COG0825	malonyl-CoA metabolic process
FOKN1_2062	COG1136	(ABC) transporter
FOKN1_2062	COG0577	efflux transmembrane transporter activity
FOKN1_2063	COG0577	efflux transmembrane transporter activity
FOKN1_2063	COG1136	(ABC) transporter
FOKN1_2064	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOKN1_2067	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOKN1_2068	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOKN1_2069	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOKN1_2070	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FOKN1_2074	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
FOKN1_2075	COG0575	Belongs to the CDS family
FOKN1_2076	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FOKN1_2077	COG0233	cytoplasmic translational termination
FOKN1_2078	COG0528	UMP kinase activity
FOKN1_2079	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
FOKN1_2080	COG0052	Belongs to the universal ribosomal protein uS2 family
FOKN1_2081	COG0024	Methionine aminopeptidase
FOKN1_2082	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FOKN1_2088	COG2171	N-acyltransferase activity
FOKN1_2089	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOKN1_2089	COG2111	Na H antiporter
FOKN1_2090	COG1006	Multisubunit Na H antiporter MnhC subunit
FOKN1_2091	COG0651	ATP synthesis coupled electron transport
FOKN1_2093	COG2212	antiporter activity
FOKN1_2094	COG1320	monovalent cation:proton antiporter activity
FOKN1_2098	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FOKN1_2099	COG2133	pyrroloquinoline quinone binding
FOKN1_2102	COG0798	PFAM Bile acid sodium symporter
FOKN1_2103	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FOKN1_2104	COG0640	Transcriptional regulator
FOKN1_2106	COG1393	Belongs to the ArsC family
FOKN1_2107	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FOKN1_2114	COG2983	Belongs to the UPF0260 family
FOKN1_2115	COG4106	trans-aconitate 2-methyltransferase activity
FOKN1_2116	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FOKN1_2117	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FOKN1_2120	COG2161	toxin-antitoxin pair type II binding
FOKN1_2124	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FOKN1_2124	COG3153	acetyltransferase
FOKN1_2125	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FOKN1_2126	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
FOKN1_2128	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOKN1_2129	COG0668	transmembrane transport
FOKN1_2130	COG1472	Belongs to the glycosyl hydrolase 3 family
FOKN1_2132	COG0601	transmembrane transport
FOKN1_2137	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FOKN1_2138	COG1053	succinate dehydrogenase
FOKN1_2139	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FOKN1_2143	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FOKN1_2144	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FOKN1_2145	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FOKN1_2149	COG0776	regulation of translation
FOKN1_2151	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
FOKN1_2152	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
FOKN1_2153	COG0291	Belongs to the bacterial ribosomal protein bL35 family
FOKN1_2154	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FOKN1_2155	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FOKN1_2157	COG1858	cytochrome C peroxidase
FOKN1_2158	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FOKN1_2165	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FOKN1_2166	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOKN1_2173	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
FOKN1_2173	COG0662	Cupin 2, conserved barrel domain protein
FOKN1_2174	COG1596	polysaccharide export
FOKN1_2174	COG1555	photosystem II stabilization
FOKN1_2175	COG0284	orotidine-5'-phosphate decarboxylase activity
FOKN1_2176	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
FOKN1_2178	COG0776	regulation of translation
FOKN1_2180	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
FOKN1_2181	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FOKN1_2182	COG0287	Prephenate dehydrogenase
FOKN1_2183	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FOKN1_2184	COG1605	Chorismate mutase
FOKN1_2184	COG0077	Prephenate dehydratase
FOKN1_2185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FOKN1_2186	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FOKN1_2188	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
FOKN1_2190	COG2885	chlorophyll binding
FOKN1_2190	COG3047	cAMP biosynthetic process
FOKN1_2191	COG0668	transmembrane transport
FOKN1_2192	COG0402	S-adenosylhomocysteine deaminase activity
FOKN1_2194	COG0546	phosphoglycolate phosphatase activity
FOKN1_2195	COG1322	Protein conserved in bacteria
FOKN1_2196	COG1562	ergosterol biosynthetic process
FOKN1_2198	COG1233	COG1233 Phytoene dehydrogenase and related
FOKN1_2199	COG1028	Short-chain dehydrogenase reductase Sdr
FOKN1_2201	COG3706	GGDEF domain
FOKN1_2203	COG1187	pseudouridine synthase activity
FOKN1_2204	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FOKN1_2206	COG0180	Tryptophanyl-tRNA synthetase
FOKN1_2207	COG1994	Peptidase M50
FOKN1_2208	COG0009	L-threonylcarbamoyladenylate synthase
FOKN1_2209	COG0613	PHP domain protein
FOKN1_2210	COG2917	probably involved in intracellular septation
FOKN1_2211	COG2350	Protein conserved in bacteria
FOKN1_2213	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOKN1_2214	COG0455	bacterial-type flagellum organization
FOKN1_2217	COG0084	hydrolase, TatD family'
FOKN1_2218	COG3100	YcgL domain-containing protein
FOKN1_2218	COG0561	phosphatase activity
FOKN1_2221	COG0589	response to stress
FOKN1_2227	COG2944	sequence-specific DNA binding
FOKN1_2228	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
FOKN1_2234	COG0732	type I restriction modification DNA specificity domain
FOKN1_2243	COG2963	transposase activity
FOKN1_2244	COG2801	Transposase and inactivated derivatives
FOKN1_2249	COG1067	ATP-dependent peptidase activity
FOKN1_2250	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FOKN1_2253	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
FOKN1_2253	COG1796	DNA polymerase
FOKN1_2254	COG0191	fructose-bisphosphate aldolase activity
FOKN1_2256	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FOKN1_2260	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FOKN1_2267	COG4251	negative regulation of phosphorylation
FOKN1_2267	COG2203	Gaf domain
FOKN1_2267	COG3706	GGDEF domain
FOKN1_2267	COG5001	Diguanylate cyclase
FOKN1_2269	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOKN1_2271	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
FOKN1_2273	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FOKN1_2276	COG1752	Esterase of the alpha-beta hydrolase superfamily
FOKN1_2279	COG0543	2 iron, 2 sulfur cluster binding
FOKN1_2282	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
FOKN1_2289	COG0298	carbon dioxide binding
FOKN1_2290	COG0375	protein maturation
FOKN1_2292	COG0409	Hydrogenase expression formation protein
FOKN1_2297	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
FOKN1_2300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOKN1_2303	COG0457	Tetratricopeptide repeat
FOKN1_2306	COG0719	Fe-S assembly protein
FOKN1_2307	COG0396	ATPase activity
FOKN1_2308	COG0719	Fe-S assembly protein
FOKN1_2309	COG2151	metal-sulfur cluster biosynthetic enzyme
FOKN1_2310	COG0316	Belongs to the HesB IscA family
FOKN1_2311	COG2166	iron-sulfur cluster assembly
FOKN1_2313	COG0438	transferase activity, transferring glycosyl groups
FOKN1_2320	COG0438	transferase activity, transferring glycosyl groups
FOKN1_2321	COG0438	transferase activity, transferring glycosyl groups
FOKN1_2322	COG0367	asparagine synthase
FOKN1_2323	COG0438	transferase activity, transferring glycosyl groups
FOKN1_2329	COG3267	Type II secretory pathway component ExeA
FOKN1_2329	COG3409	Peptidoglycan-binding domain 1 protein
FOKN1_2331	COG0489	protein tyrosine kinase activity
FOKN1_2335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOKN1_2340	COG2204	response regulator
FOKN1_2341	COG2205	protein histidine kinase activity
FOKN1_2342	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FOKN1_2345	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOKN1_2346	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FOKN1_2347	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOKN1_2348	COG0328	RNA-DNA hybrid ribonuclease activity
FOKN1_2350	COG1388	LysM domain
FOKN1_2350	COG0741	lytic transglycosylase activity
FOKN1_2352	COG0746	molybdenum cofactor guanylyltransferase activity
FOKN1_2353	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
FOKN1_2353	COG3608	succinylglutamate desuccinylase aspartoacylase
FOKN1_2357	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FOKN1_2360	COG0537	adenosine 5'-monophosphoramidase activity
FOKN1_2361	COG0058	SHG alpha-glucan phosphorylase activity
FOKN1_2368	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FOKN1_2372	COG3300	MHYT domain
FOKN1_2372	COG5001	Diguanylate cyclase
FOKN1_2375	COG1454	alcohol dehydrogenase
FOKN1_2377	COG1959	2 iron, 2 sulfur cluster binding
FOKN1_2379	COG0033	Phosphoglucomutase
FOKN1_2381	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FOKN1_2383	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FOKN1_2384	COG0501	Belongs to the peptidase M48B family
FOKN1_2386	COG2154	pterin-4-alpha-carbinolamine dehydratase
FOKN1_2387	COG1162	GTPase activity
FOKN1_2388	COG0537	adenosine 5'-monophosphoramidase activity
FOKN1_2391	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FOKN1_2392	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
FOKN1_2393	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FOKN1_2397	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOKN1_2400	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FOKN1_2405	COG3002	Belongs to the UPF0753 family
FOKN1_2406	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FOKN1_2410	COG2081	HI0933 family
FOKN1_2412	COG0784	Response regulator, receiver
FOKN1_2412	COG2205	protein histidine kinase activity
FOKN1_2412	COG2198	Histidine kinase
FOKN1_2413	COG1024	Enoyl-CoA hydratase
FOKN1_2414	COG3706	GGDEF domain
FOKN1_2420	COG0058	SHG alpha-glucan phosphorylase activity
FOKN1_2422	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
FOKN1_2423	COG0527	aspartate kinase activity
FOKN1_2424	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
FOKN1_2425	COG2137	regulation of response to DNA damage stimulus
FOKN1_2426	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FOKN1_2428	COG1546	Belongs to the CinA family
FOKN1_2430	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
FOKN1_2437	COG5001	Diguanylate cyclase
FOKN1_2437	COG4251	negative regulation of phosphorylation
FOKN1_2437	COG3706	GGDEF domain
FOKN1_2437	COG2203	Gaf domain
FOKN1_2438	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FOKN1_2440	COG1074	ATP-dependent DNA helicase activity
FOKN1_2441	COG3118	belongs to the thioredoxin family
FOKN1_2442	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FOKN1_2444	COG0318	PFAM AMP-dependent synthetase and ligase
FOKN1_2448	COG0746	molybdenum cofactor guanylyltransferase activity
FOKN1_2449	COG1763	Mo-molybdopterin cofactor biosynthetic process
FOKN1_2451	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
FOKN1_2452	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOKN1_2453	COG3706	GGDEF domain
FOKN1_2459	COG0659	secondary active sulfate transmembrane transporter activity
FOKN1_2460	COG0589	response to stress
FOKN1_2461	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FOKN1_2462	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FOKN1_2463	COG0326	Molecular chaperone. Has ATPase activity
FOKN1_2464	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FOKN1_2466	COG0335	large ribosomal subunit rRNA binding
FOKN1_2467	COG0336	Belongs to the RNA methyltransferase TrmD family
FOKN1_2468	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FOKN1_2469	COG0228	four-way junction DNA binding
FOKN1_2470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FOKN1_2472	COG4137	Cytochrome C assembly protein
FOKN1_2473	COG4536	flavin adenine dinucleotide binding
FOKN1_2480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FOKN1_2481	COG0305	Participates in initiation and elongation during chromosome replication
FOKN1_2482	COG0359	binds to the 23S rRNA
FOKN1_2484	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
FOKN1_2485	COG2965	DNA replication, synthesis of RNA primer
FOKN1_2486	COG0360	Binds together with S18 to 16S ribosomal RNA
FOKN1_2487	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FOKN1_2488	COG2885	chlorophyll binding
FOKN1_2489	COG0557	exoribonuclease II activity
FOKN1_2492	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FOKN1_2493	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
FOKN1_2495	COG0330	HflC and HflK could
FOKN1_2496	COG0330	HflC and HflK could
FOKN1_2497	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FOKN1_2498	COG1923	regulation of RNA biosynthetic process
FOKN1_2499	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
FOKN1_2500	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FOKN1_2501	COG0860	N-Acetylmuramoyl-L-alanine amidase
FOKN1_2502	COG0802	atpase or kinase
FOKN1_2503	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FOKN1_2503	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FOKN1_2508	COG0792	nuclease activity
FOKN1_2509	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
FOKN1_2510	COG2823	Periplasmic or secreted lipoprotein
FOKN1_2512	COG2200	EAL domain
FOKN1_2512	COG3287	FIST C domain
FOKN1_2512	COG2199	diguanylate cyclase activity
FOKN1_2513	COG5002	protein histidine kinase activity
FOKN1_2522	COG2076	Multidrug Resistance protein
FOKN1_2524	COG3549	Plasmid maintenance system killer
FOKN1_2526	COG2801	Transposase and inactivated derivatives
FOKN1_2540	COG2969	positive regulation of protein catabolic process
FOKN1_2541	COG0625	glutathione transferase activity
FOKN1_2542	COG2857	Cytochrome c1
FOKN1_2543	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
FOKN1_2544	COG0723	plastoquinol--plastocyanin reductase activity
FOKN1_2546	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FOKN1_2547	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FOKN1_2548	COG0367	asparagine synthase
FOKN1_2552	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FOKN1_2553	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
FOKN1_2555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FOKN1_2556	COG0581	inorganic phosphate transmembrane transporter activity
FOKN1_2559	COG0137	argininosuccinate synthase activity
FOKN1_2561	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOKN1_2562	COG0508	dehydrogenase complex catalyzes the overall conversion of
FOKN1_2562	COG0022	dehydrogenase e1 component
FOKN1_2563	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FOKN1_2564	COG0418	dihydroorotase activity
FOKN1_2566	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOKN1_2569	COG0745	RESPONSE REGULATOR receiver
FOKN1_2572	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
FOKN1_2573	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
FOKN1_2574	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
FOKN1_2575	COG2255	four-way junction helicase activity
FOKN1_2577	COG0617	tRNA 3'-terminal CCA addition
FOKN1_2582	COG1714	RDD family
FOKN1_2583	COG0795	lipopolysaccharide-transporting ATPase activity
FOKN1_2584	COG0795	lipopolysaccharide-transporting ATPase activity
FOKN1_2585	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
FOKN1_2587	COG0525	valine-tRNA ligase activity
FOKN1_2589	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
FOKN1_2594	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
FOKN1_2595	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FOKN1_2597	COG1573	uracil-dna glycosylase
FOKN1_2598	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FOKN1_2603	COG3437	response regulator, receiver
FOKN1_2604	COG1183	phosphatidylcholine synthase activity
FOKN1_2605	COG0688	phosphatidylethanolamine metabolic process
FOKN1_2606	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
FOKN1_2607	COG0440	acetolactate synthase activity
FOKN1_2608	COG0028	Belongs to the TPP enzyme family
FOKN1_2610	COG0442	prolyl-tRNA aminoacylation
FOKN1_2611	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
FOKN1_2614	COG5265	(ABC) transporter
FOKN1_2620	COG1360	Flagellar Motor Protein
FOKN1_2621	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
FOKN1_2622	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
FOKN1_2623	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOKN1_2625	COG0300	oxidoreductase activity
FOKN1_2628	COG0542	response to heat
FOKN1_2630	COG0242	peptide deformylase activity
FOKN1_2631	COG3830	Belongs to the UPF0237 family
FOKN1_2634	COG0564	pseudouridine synthase activity
FOKN1_2638	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
FOKN1_2639	COG0045	succinate-CoA ligase (ADP-forming) activity
FOKN1_2647	COG1216	Glycosyl transferase, family 2
FOKN1_2650	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
FOKN1_2651	COG0237	dephospho-CoA kinase activity
FOKN1_2652	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
FOKN1_2655	COG0494	nUDIX hydrolase
FOKN1_2657	COG0653	protein targeting
FOKN1_2658	COG0739	heme binding
FOKN1_2660	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
FOKN1_2661	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FOKN1_2665	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FOKN1_2667	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FOKN1_2668	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
FOKN1_2669	COG0772	Belongs to the SEDS family
FOKN1_2670	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
FOKN1_2671	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FOKN1_2672	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FOKN1_2675	COG3116	cell division
FOKN1_2676	COG0275	rRNA processing
FOKN1_2677	COG2001	Belongs to the MraZ family
FOKN1_2679	COG0629	single-stranded DNA binding
FOKN1_2680	COG2814	Major facilitator Superfamily
FOKN1_2683	COG0203	ribosomal protein L17
FOKN1_2684	COG0202	RNA polymerase activity
FOKN1_2685	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
FOKN1_2686	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
FOKN1_2687	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FOKN1_2688	COG0201	protein transport
FOKN1_2689	COG0200	Binds to the 23S rRNA
FOKN1_2690	COG1841	ribosomal large subunit assembly
FOKN1_2691	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
FOKN1_2692	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
FOKN1_2693	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
FOKN1_2694	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
FOKN1_2695	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
FOKN1_2696	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FOKN1_2697	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
FOKN1_2698	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
FOKN1_2699	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
FOKN1_2700	COG0255	Belongs to the universal ribosomal protein uL29 family
FOKN1_2701	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
FOKN1_2702	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
FOKN1_2703	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
FOKN1_2704	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
FOKN1_2705	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FOKN1_2706	COG0089	rRNA binding
FOKN1_2707	COG0088	Forms part of the polypeptide exit tunnel
FOKN1_2708	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
FOKN1_2709	COG0051	transcription antitermination factor activity, RNA binding
FOKN1_2710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOKN1_2711	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FOKN1_2712	COG0049	tRNA binding
FOKN1_2713	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
FOKN1_2714	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
FOKN1_2715	COG0085	RNA polymerase activity
FOKN1_2716	COG0222	ribosome binding
FOKN1_2717	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
FOKN1_2718	COG0081	regulation of translation
FOKN1_2719	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
FOKN1_2723	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
FOKN1_2730	COG2738	Putative neutral zinc metallopeptidase
FOKN1_2733	COG0697	spore germination
FOKN1_2734	COG0004	ammonium transporteR
FOKN1_2737	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FOKN1_2738	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FOKN1_2742	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
FOKN1_2743	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FOKN1_2743	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FOKN1_2752	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FOKN1_2753	COG0739	heme binding
FOKN1_2756	COG0316	Belongs to the HesB IscA family
FOKN1_2759	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
FOKN1_2762	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOKN1_2768	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
FOKN1_2769	COG0494	nUDIX hydrolase
FOKN1_2772	COG1120	ATPase activity
FOKN1_2775	COG4206	TonB-dependent receptor
FOKN1_2777	COG2096	Adenosyltransferase
FOKN1_2778	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
FOKN1_2779	COG1492	cobalamin metabolic process
FOKN1_2780	COG0432	Pfam Uncharacterised protein family UPF0047
FOKN1_2783	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FOKN1_2792	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
FOKN1_2796	COG1643	Atp-dependent helicase
FOKN1_2798	COG2270	Major facilitator Superfamily
FOKN1_2800	COG1444	tRNA N-acetyltransferase activity
FOKN1_2803	COG1331	Highly conserved protein containing a thioredoxin domain
FOKN1_2808	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FOKN1_2810	COG2204	response regulator
FOKN1_2811	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FOKN1_2812	COG1518	maintenance of DNA repeat elements
FOKN1_2815	COG1857	crispr-associated protein
FOKN1_2818	COG1203	CRISPR-associated helicase, Cas3
FOKN1_2822	COG0647	UMP catabolic process
FOKN1_2824	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FOKN1_2825	COG2226	methyltransferase
FOKN1_2827	COG1104	cysteine desulfurase activity
FOKN1_2829	COG0012	GTP binding
FOKN1_2830	COG0193	aminoacyl-tRNA hydrolase activity
FOKN1_2831	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
FOKN1_2832	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FOKN1_2834	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
FOKN1_2835	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FOKN1_2837	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
FOKN1_2838	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
FOKN1_2839	COG2890	protein-(glutamine-N5) methyltransferase activity
FOKN1_2841	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FOKN1_2843	COG3647	Membrane
FOKN1_2844	COG0561	phosphatase activity
FOKN1_2844	COG3100	YcgL domain-containing protein
FOKN1_2846	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOKN1_2847	COG0154	amidase activity
FOKN1_2848	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FOKN1_2849	COG1077	Cell shape determining protein MreB Mrl
FOKN1_2850	COG1792	Involved in formation and maintenance of cell shape
FOKN1_2851	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FOKN1_2852	COG0768	penicillin binding
FOKN1_2853	COG0772	Belongs to the SEDS family
FOKN1_2854	COG2951	lytic endotransglycosylase activity
FOKN1_2856	COG1686	Belongs to the peptidase S11 family
FOKN1_2862	COG2921	Belongs to the UPF0250 family
FOKN1_2863	COG0321	lipoyl(octanoyl) transferase activity
FOKN1_2864	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FOKN1_2871	COG3178	'Phosphotransferase
FOKN1_2874	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
FOKN1_2875	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FOKN1_2876	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FOKN1_2877	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FOKN1_2879	COG0589	response to stress
FOKN1_2882	COG0363	glucosamine-6-phosphate deaminase activity
FOKN1_2883	COG0837	glucose binding
FOKN1_2884	COG2967	ApaG domain
FOKN1_2888	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
FOKN1_2890	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
FOKN1_2894	COG0463	Glycosyl transferase, family 2
FOKN1_2895	COG1331	Highly conserved protein containing a thioredoxin domain
FOKN1_2896	COG2824	Alkylphosphonate utilization operon protein PhnA
FOKN1_2897	COG0425	Belongs to the sulfur carrier protein TusA family
FOKN1_2898	COG1309	transcriptional regulator
FOKN1_2902	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
FOKN1_2903	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOKN1_2904	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
FOKN1_2905	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FOKN1_2906	COG0509	glycine decarboxylation via glycine cleavage system
FOKN1_2907	COG0404	The glycine cleavage system catalyzes the degradation of glycine
FOKN1_2909	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOKN1_2910	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FOKN1_2911	COG0006	proline dipeptidase activity
FOKN1_2916	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FOKN1_2919	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FOKN1_2920	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
FOKN1_2921	COG0247	lactate metabolic process
FOKN1_2923	COG3047	cAMP biosynthetic process
FOKN1_2925	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FOKN1_2926	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
FOKN1_2929	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
FOKN1_2930	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
FOKN1_2932	COG1765	OsmC-like protein
FOKN1_2934	COG0134	indole-3-glycerol-phosphate synthase activity
FOKN1_2935	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FOKN1_2936	COG0512	Glutamine amidotransferase of anthranilate synthase
FOKN1_2939	COG0546	phosphoglycolate phosphatase activity
FOKN1_2943	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
FOKN1_2945	COG1515	deoxyribonuclease V activity
FOKN1_2948	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FOKN1_2953	COG3267	Type II secretory pathway component ExeA
FOKN1_2953	COG3409	Peptidoglycan-binding domain 1 protein
FOKN1_2958	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FOKN1_2960	COG0071	Belongs to the small heat shock protein (HSP20) family
FOKN1_2973	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FOKN1_2979	COG0191	fructose-bisphosphate aldolase activity
FOKN1_2980	COG0469	pyruvate kinase activity
FOKN1_2981	COG0126	phosphoglycerate kinase activity
FOKN1_2982	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FOKN1_2983	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FOKN1_2986	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
FOKN1_2987	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FOKN1_2988	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FOKN1_2989	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FOKN1_2991	COG2204	response regulator
FOKN1_2994	COG0471	metal ion transport
FOKN1_2997	COG2201	protein-glutamate methylesterase activity
FOKN1_2998	COG0643	Histidine kinase
FOKN1_2998	COG2198	Histidine kinase
FOKN1_3000	COG0840	transmembrane signaling receptor activity
FOKN1_3005	COG0189	ligase activity
FOKN1_3011	COG1678	Uncharacterized ACR, COG1678
FOKN1_3012	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FOKN1_3014	COG0540	Belongs to the ATCase OTCase family
FOKN1_3023	COG1872	DUF167
FOKN1_3027	COG0708	Exodeoxyribonuclease III
FOKN1_3028	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
FOKN1_3031	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
FOKN1_3033	COG0756	dUTP diphosphatase activity
FOKN1_3035	COG2003	Belongs to the UPF0758 family
FOKN1_3036	COG0227	Belongs to the bacterial ribosomal protein bL28 family
FOKN1_3037	COG0267	Belongs to the bacterial ribosomal protein bL33 family
FOKN1_3040	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
FOKN1_3042	COG1131	(ABC) transporter
FOKN1_3046	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FOKN1_3047	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
FOKN1_3050	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FOKN1_3051	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
FOKN1_3052	COG0742	ribosomal rna small subunit methyltransferase
FOKN1_3054	COG0612	Peptidase, M16
FOKN1_3055	COG0612	Peptidase, M16
FOKN1_3056	COG0552	protein localization to endoplasmic reticulum
FOKN1_3057	COG2884	Cell division ATP-binding protein ftsE
FOKN1_3058	COG2177	Part of the ABC transporter FtsEX involved in
FOKN1_3059	COG0745	RESPONSE REGULATOR receiver
FOKN1_3059	COG3706	GGDEF domain
FOKN1_3063	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
FOKN1_3067	COG0724	RNA recognition motif
FOKN1_3068	COG1278	Cold shock
FOKN1_3072	COG2204	response regulator
FOKN1_3073	COG3852	Histidine kinase