locus-tag	class	description
THMIRHAT_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
THMIRHAT_00020	COG0592	DNA-directed DNA polymerase activity
THMIRHAT_00030	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
THMIRHAT_00040	COG0187	DNA topoisomerase II activity
THMIRHAT_00050	COG3954	Phosphoribulokinase
THMIRHAT_00110	COG4783	chaperone-mediated protein folding
THMIRHAT_00120	COG0009	L-threonylcarbamoyladenylate synthase
THMIRHAT_00170	COG0840	transmembrane signaling receptor activity
THMIRHAT_00190	COG0415	Belongs to the DNA photolyase family
THMIRHAT_00210	COG3046	protein related to deoxyribodipyrimidine photolyase
THMIRHAT_00240	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
THMIRHAT_00250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
THMIRHAT_00260	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
THMIRHAT_00260	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
THMIRHAT_00340	COG0778	Nitroreductase
THMIRHAT_00350	COG0432	Pfam Uncharacterised protein family UPF0047
THMIRHAT_00360	COG0840	transmembrane signaling receptor activity
THMIRHAT_00370	COG0840	transmembrane signaling receptor activity
THMIRHAT_00430	COG1283	sodium-dependent phosphate transmembrane transporter activity
THMIRHAT_00440	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
THMIRHAT_00450	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
THMIRHAT_00460	COG0784	Response regulator, receiver
THMIRHAT_00460	COG5002	protein histidine kinase activity
THMIRHAT_00460	COG2198	Histidine kinase
THMIRHAT_00500	COG2853	Lipoprotein
THMIRHAT_00570	COG1858	cytochrome C peroxidase
THMIRHAT_00590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
THMIRHAT_00600	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
THMIRHAT_00610	COG1333	cytochrome c biogenesis protein
THMIRHAT_00620	COG0218	Necessary for normal cell division and for the maintenance of normal septation
THMIRHAT_00650	COG0514	ATP-dependent DNA helicase (RecQ)
THMIRHAT_00680	COG1252	NADH dehydrogenase
THMIRHAT_00700	COG2837	iron assimilation
THMIRHAT_00730	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
THMIRHAT_00740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
THMIRHAT_00750	COG5001	Diguanylate cyclase
THMIRHAT_00750	COG3706	GGDEF domain
THMIRHAT_00750	COG2203	Gaf domain
THMIRHAT_00750	COG4251	negative regulation of phosphorylation
THMIRHAT_00770	COG0330	HflC and HflK could
THMIRHAT_00790	COG2731	YhcH YjgK YiaL family protein
THMIRHAT_00810	COG0167	dihydroorotate dehydrogenase activity
THMIRHAT_00820	COG2095	MarC family integral membrane protein
THMIRHAT_00870	COG0450	alkyl hydroperoxide reductase
THMIRHAT_00940	COG0714	Associated with various cellular activities
THMIRHAT_00960	COG0784	Response regulator, receiver
THMIRHAT_00960	COG2205	protein histidine kinase activity
THMIRHAT_00980	COG0500	methyltransferase
THMIRHAT_00990	COG2226	methyltransferase
THMIRHAT_01010	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
THMIRHAT_01020	COG0714	Associated with various cellular activities
THMIRHAT_01130	COG0515	serine threonine protein kinase
THMIRHAT_01150	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
THMIRHAT_01160	COG3706	GGDEF domain
THMIRHAT_01170	COG0165	Argininosuccinate lyase
THMIRHAT_01190	COG0181	hydroxymethylbilane synthase activity
THMIRHAT_01250	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
THMIRHAT_01260	COG0857	belongs to the CobB CobQ family
THMIRHAT_01260	COG0280	phosphate acetyltransferase
THMIRHAT_01270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
THMIRHAT_01300	COG0220	tRNA (guanine-N7-)-methyltransferase activity
THMIRHAT_01310	COG1194	a g-specific adenine glycosylase
THMIRHAT_01320	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
THMIRHAT_01330	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
THMIRHAT_01350	COG0445	tRNA wobble uridine modification
THMIRHAT_01360	COG0357	Ribosomal RNA small subunit methyltransferase G
THMIRHAT_01370	COG1192	Involved in chromosome partitioning
THMIRHAT_01410	COG0356	it plays a direct role in the translocation of protons across the membrane
THMIRHAT_01420	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
THMIRHAT_01430	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
THMIRHAT_01440	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
THMIRHAT_01450	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
THMIRHAT_01470	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
THMIRHAT_01480	COG0355	proton-transporting ATP synthase activity, rotational mechanism
THMIRHAT_01490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
THMIRHAT_01500	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
THMIRHAT_01540	COG3161	chorismate lyase activity
THMIRHAT_01550	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
THMIRHAT_01560	COG0004	ammonium transporteR
THMIRHAT_01580	COG0803	Belongs to the bacterial solute-binding protein 9 family
THMIRHAT_01590	COG1121	(ABC) transporter
THMIRHAT_01600	COG1321	iron dependent repressor
THMIRHAT_01600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
THMIRHAT_01610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
THMIRHAT_01630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
THMIRHAT_01640	COG1758	RNA polymerase activity
THMIRHAT_01660	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
THMIRHAT_01670	COG1454	alcohol dehydrogenase
THMIRHAT_01680	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
THMIRHAT_01690	COG0194	GDP metabolic process
THMIRHAT_01700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
THMIRHAT_01710	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
THMIRHAT_01720	COG0676	glucose-6-phosphate 1-epimerase activity
THMIRHAT_01740	COG3706	GGDEF domain
THMIRHAT_01750	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
THMIRHAT_01780	COG0840	transmembrane signaling receptor activity
THMIRHAT_01790	COG5002	protein histidine kinase activity
THMIRHAT_01790	COG2205	protein histidine kinase activity
THMIRHAT_01790	COG0784	Response regulator, receiver
THMIRHAT_01820	COG0784	Response regulator, receiver
THMIRHAT_01820	COG2205	protein histidine kinase activity
THMIRHAT_01840	COG0840	transmembrane signaling receptor activity
THMIRHAT_01850	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
THMIRHAT_01900	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
THMIRHAT_01930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
THMIRHAT_01970	COG0840	transmembrane signaling receptor activity
THMIRHAT_02000	COG0156	8-amino-7-oxononanoate synthase activity
THMIRHAT_02010	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
THMIRHAT_02020	COG1040	competence protein
THMIRHAT_02040	COG4783	chaperone-mediated protein folding
THMIRHAT_02090	COG2201	protein-glutamate methylesterase activity
THMIRHAT_02120	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
THMIRHAT_02130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
THMIRHAT_02140	COG0537	adenosine 5'-monophosphoramidase activity
THMIRHAT_02150	COG0140	phosphoribosyl-ATP diphosphatase activity
THMIRHAT_02160	COG0107	imidazoleglycerol-phosphate synthase activity
THMIRHAT_02170	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
THMIRHAT_02180	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
THMIRHAT_02190	COG0131	Imidazoleglycerol-phosphate dehydratase
THMIRHAT_02200	COG3278	Belongs to the heme-copper respiratory oxidase family
THMIRHAT_02250	COG0348	domain, Protein
THMIRHAT_02270	COG2217	Heavy metal translocating P-type atpase
THMIRHAT_02290	COG0513	Belongs to the DEAD box helicase family
THMIRHAT_02300	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
THMIRHAT_02310	COG0842	Transport permease protein
THMIRHAT_02310	COG1129	ABC transporter
THMIRHAT_02320	COG1129	ABC transporter
THMIRHAT_02320	COG0842	Transport permease protein
THMIRHAT_02330	COG0842	Transport permease protein
THMIRHAT_02340	COG0840	transmembrane signaling receptor activity
THMIRHAT_02340	COG0840	transmembrane signaling receptor activity
THMIRHAT_02360	COG3300	MHYT domain
THMIRHAT_02360	COG5001	Diguanylate cyclase
THMIRHAT_02370	COG2801	Transposase and inactivated derivatives
THMIRHAT_02390	COG0493	'glutamate synthase
THMIRHAT_02400	COG0069	glutamate synthase activity
THMIRHAT_02400	COG0067	glutamate synthase
THMIRHAT_02400	COG0070	glutamate synthase
THMIRHAT_02410	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
THMIRHAT_02440	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
THMIRHAT_02450	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
THMIRHAT_02460	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
THMIRHAT_02470	COG0167	dihydroorotate dehydrogenase activity
THMIRHAT_02480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
THMIRHAT_02510	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
THMIRHAT_02520	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
THMIRHAT_02560	COG0552	protein localization to endoplasmic reticulum
THMIRHAT_02570	COG0612	Peptidase, M16
THMIRHAT_02580	COG0612	Peptidase, M16
THMIRHAT_02590	COG0840	transmembrane signaling receptor activity
THMIRHAT_02630	COG0742	ribosomal rna small subunit methyltransferase
THMIRHAT_02660	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
THMIRHAT_02720	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
THMIRHAT_02750	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
THMIRHAT_02760	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
THMIRHAT_02780	COG3706	GGDEF domain
THMIRHAT_02800	COG0227	Belongs to the bacterial ribosomal protein bL28 family
THMIRHAT_02820	COG2003	Belongs to the UPF0758 family
THMIRHAT_02850	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
THMIRHAT_02860	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
THMIRHAT_02900	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
THMIRHAT_02950	COG2200	EAL domain
THMIRHAT_02950	COG2199	diguanylate cyclase activity
THMIRHAT_02950	COG3287	FIST C domain
THMIRHAT_02970	COG0756	dUTP diphosphatase activity
THMIRHAT_03010	COG1028	Short-chain dehydrogenase reductase Sdr
THMIRHAT_03010	COG3347	Dehydrogenase
THMIRHAT_03060	COG0745	RESPONSE REGULATOR receiver
THMIRHAT_03070	COG1666	GTP binding
THMIRHAT_03080	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
THMIRHAT_03100	COG0840	transmembrane signaling receptor activity
THMIRHAT_03100	COG0840	transmembrane signaling receptor activity
THMIRHAT_03130	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
THMIRHAT_03160	COG0248	Ppx GppA phosphatase
THMIRHAT_03180	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
THMIRHAT_03210	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
THMIRHAT_03230	COG1012	belongs to the aldehyde dehydrogenase family
THMIRHAT_03250	COG0513	Belongs to the DEAD box helicase family
THMIRHAT_03260	COG1611	Belongs to the LOG family
THMIRHAT_03270	COG0628	permease
THMIRHAT_03290	COG1469	GTP cyclohydrolase I activity
THMIRHAT_03300	COG0523	cobalamin synthesis protein
THMIRHAT_03310	COG0579	oxidoreductase
THMIRHAT_03320	COG0640	Transcriptional regulator
THMIRHAT_03330	COG0701	Predicted permease
THMIRHAT_03350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
THMIRHAT_03380	COG1187	pseudouridine synthase activity
THMIRHAT_03390	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
THMIRHAT_03410	COG1253	flavin adenine dinucleotide binding
THMIRHAT_03420	COG4804	nuclease activity
THMIRHAT_03450	COG0742	ribosomal rna small subunit methyltransferase
THMIRHAT_03470	COG0509	glycine decarboxylation via glycine cleavage system
THMIRHAT_03510	COG0019	diaminopimelate decarboxylase activity
THMIRHAT_03530	COG0400	carboxylic ester hydrolase activity
THMIRHAT_03590	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
THMIRHAT_03620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
THMIRHAT_03650	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
THMIRHAT_03660	COG0840	transmembrane signaling receptor activity
THMIRHAT_03670	COG0746	molybdenum cofactor guanylyltransferase activity
THMIRHAT_03690	COG2814	Major facilitator Superfamily
THMIRHAT_03700	COG0784	Response regulator, receiver
THMIRHAT_03700	COG2205	protein histidine kinase activity
THMIRHAT_03720	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
THMIRHAT_03720	COG4651	solute:proton antiporter activity
THMIRHAT_03730	COG0589	response to stress
THMIRHAT_03740	COG1620	l-lactate permease
THMIRHAT_03780	COG0142	geranyltranstransferase activity
THMIRHAT_03790	COG0261	This protein binds to 23S rRNA in the presence of protein L20
THMIRHAT_03800	COG0211	Belongs to the bacterial ribosomal protein bL27 family
THMIRHAT_03810	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
THMIRHAT_03820	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
THMIRHAT_03830	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
THMIRHAT_03840	COG0459	protein refolding
THMIRHAT_03850	COG3706	GGDEF domain
THMIRHAT_03860	COG0210	DNA helicase
THMIRHAT_03880	COG2813	Specifically methylates the guanine in position
THMIRHAT_03910	COG0585	pseudouridine synthase activity
THMIRHAT_03920	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
THMIRHAT_03940	COG0791	NLP P60 protein
THMIRHAT_03970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
THMIRHAT_03980	COG3100	YcgL domain-containing protein
THMIRHAT_04000	COG0617	tRNA 3'-terminal CCA addition
THMIRHAT_04040	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
THMIRHAT_04050	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
THMIRHAT_04060	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
THMIRHAT_04070	COG0126	phosphoglycerate kinase activity
THMIRHAT_04080	COG0469	pyruvate kinase activity
THMIRHAT_04140	COG1459	type II secretion system
THMIRHAT_04240	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
THMIRHAT_04250	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
THMIRHAT_04270	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
THMIRHAT_04280	COG0546	phosphoglycolate phosphatase activity
THMIRHAT_04310	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
THMIRHAT_04320	COG0134	indole-3-glycerol-phosphate synthase activity
THMIRHAT_04330	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
THMIRHAT_04340	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
THMIRHAT_04360	COG1765	OsmC-like protein
THMIRHAT_04380	COG0513	Belongs to the DEAD box helicase family
THMIRHAT_04390	COG1278	Cold shock
THMIRHAT_04400	COG0564	pseudouridine synthase activity
THMIRHAT_04410	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
THMIRHAT_04420	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
THMIRHAT_04440	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
THMIRHAT_04450	COG0081	regulation of translation
THMIRHAT_04460	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
THMIRHAT_04480	COG0085	RNA polymerase activity
THMIRHAT_04490	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
THMIRHAT_04500	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
THMIRHAT_04510	COG0049	tRNA binding
THMIRHAT_04520	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
THMIRHAT_04530	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
THMIRHAT_04540	COG0051	transcription antitermination factor activity, RNA binding
THMIRHAT_04550	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
THMIRHAT_04560	COG0088	Forms part of the polypeptide exit tunnel
THMIRHAT_04570	COG0089	rRNA binding
THMIRHAT_04580	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
THMIRHAT_04590	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
THMIRHAT_04600	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
THMIRHAT_04610	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
THMIRHAT_04620	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
THMIRHAT_04630	COG0255	Belongs to the universal ribosomal protein uL29 family
THMIRHAT_04640	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
THMIRHAT_04650	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
THMIRHAT_04660	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
THMIRHAT_04670	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
THMIRHAT_04680	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
THMIRHAT_04690	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
THMIRHAT_04700	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
THMIRHAT_04710	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
THMIRHAT_04720	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
THMIRHAT_04730	COG1841	ribosomal large subunit assembly
THMIRHAT_04740	COG0200	Binds to the 23S rRNA
THMIRHAT_04750	COG0201	protein transport
THMIRHAT_04760	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
THMIRHAT_04770	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
THMIRHAT_04780	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
THMIRHAT_04790	COG0202	RNA polymerase activity
THMIRHAT_04800	COG0203	ribosomal protein L17
THMIRHAT_04830	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
THMIRHAT_04910	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
THMIRHAT_04920	COG0540	Belongs to the ATCase OTCase family
THMIRHAT_04930	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
THMIRHAT_04940	COG1678	Uncharacterized ACR, COG1678
THMIRHAT_04950	COG1477	protein flavinylation
THMIRHAT_04980	COG1760	l-serine dehydratase
THMIRHAT_04990	COG0564	pseudouridine synthase activity
THMIRHAT_05020	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
THMIRHAT_05020	COG0674	pyruvate-flavodoxin oxidoreductase activity
THMIRHAT_05030	COG1013	pyruvate-flavodoxin oxidoreductase activity
THMIRHAT_05060	COG1714	RDD family
THMIRHAT_05080	COG1074	ATP-dependent DNA helicase activity
THMIRHAT_05100	COG0840	transmembrane signaling receptor activity
THMIRHAT_05120	COG0792	nuclease activity
THMIRHAT_05140	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
THMIRHAT_05150	COG1793	dna ligase
THMIRHAT_05160	COG0436	Aminotransferase
THMIRHAT_05170	COG0556	nucleotide-excision repair
THMIRHAT_05240	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
THMIRHAT_05250	COG0795	lipopolysaccharide-transporting ATPase activity
THMIRHAT_05260	COG0795	lipopolysaccharide-transporting ATPase activity
THMIRHAT_05300	COG0625	glutathione transferase activity
THMIRHAT_05310	COG2969	positive regulation of protein catabolic process
THMIRHAT_05350	COG3425	synthase
THMIRHAT_05360	COG1304	FMN binding
THMIRHAT_05380	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
THMIRHAT_05390	COG0189	ligase activity
THMIRHAT_05410	COG3706	GGDEF domain
THMIRHAT_05420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
THMIRHAT_05430	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
THMIRHAT_05440	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
THMIRHAT_05450	COG2199	diguanylate cyclase activity
THMIRHAT_05450	COG2200	EAL domain
THMIRHAT_05460	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
THMIRHAT_05480	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
THMIRHAT_05480	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
THMIRHAT_05490	COG1968	undecaprenyl-diphosphatase activity
THMIRHAT_05530	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
THMIRHAT_05540	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
THMIRHAT_05550	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
THMIRHAT_05560	COG0828	Belongs to the bacterial ribosomal protein bS21 family
THMIRHAT_05570	COG1610	YqeY-like protein
THMIRHAT_05580	COG0358	DNA primase activity
THMIRHAT_05690	COG2204	response regulator
THMIRHAT_05700	COG5002	protein histidine kinase activity
THMIRHAT_05730	COG0196	riboflavin kinase activity
THMIRHAT_05760	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
THMIRHAT_05770	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
THMIRHAT_05790	COG2951	lytic endotransglycosylase activity
THMIRHAT_05800	COG0116	Belongs to the methyltransferase superfamily
THMIRHAT_05800	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
THMIRHAT_05810	COG2199	diguanylate cyclase activity
THMIRHAT_05850	COG1519	Transferase
THMIRHAT_05860	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
THMIRHAT_05860	COG0517	IMP dehydrogenase activity
THMIRHAT_05880	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
THMIRHAT_05880	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
THMIRHAT_05890	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
THMIRHAT_05910	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
THMIRHAT_05940	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
THMIRHAT_05950	COG0297	glycogen (starch) synthase activity
THMIRHAT_05960	COG0058	SHG alpha-glucan phosphorylase activity
THMIRHAT_06010	COG0745	RESPONSE REGULATOR receiver
THMIRHAT_06020	COG0745	RESPONSE REGULATOR receiver
THMIRHAT_06030	COG0217	transcriptional regulatory protein
THMIRHAT_06070	COG0151	Belongs to the GarS family
THMIRHAT_06080	COG0138	bifunctional purine biosynthesis protein purh
THMIRHAT_06090	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
THMIRHAT_06100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
THMIRHAT_06110	COG2264	protein methyltransferase activity
THMIRHAT_06120	COG0439	Biotin carboxylase
THMIRHAT_06130	COG0511	ligase activity, forming carbon-carbon bonds
THMIRHAT_06140	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
THMIRHAT_06150	COG4232	protein-disulfide reductase activity
THMIRHAT_06160	COG3030	protein affecting phage T7 exclusion by the F plasmid
THMIRHAT_06200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
THMIRHAT_06250	COG0174	glutamine synthetase
THMIRHAT_06270	COG0581	inorganic phosphate transmembrane transporter activity
THMIRHAT_06280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
THMIRHAT_06290	COG0704	Plays a role in the regulation of phosphate uptake
THMIRHAT_06300	COG0745	RESPONSE REGULATOR receiver
THMIRHAT_06320	COG0306	phosphate transporter
THMIRHAT_06340	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
THMIRHAT_06350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
THMIRHAT_06380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
THMIRHAT_06390	COG0523	cobalamin synthesis protein
THMIRHAT_06410	COG1858	cytochrome C peroxidase
THMIRHAT_06450	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
THMIRHAT_06460	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
THMIRHAT_06470	COG2001	Belongs to the MraZ family
THMIRHAT_06480	COG0275	rRNA processing
THMIRHAT_06490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
THMIRHAT_06530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
THMIRHAT_06540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
THMIRHAT_06550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
THMIRHAT_06560	COG0772	Belongs to the SEDS family
THMIRHAT_06570	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
THMIRHAT_06600	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
THMIRHAT_06610	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
THMIRHAT_06630	COG0840	transmembrane signaling receptor activity
THMIRHAT_06650	COG3437	response regulator, receiver
THMIRHAT_06660	COG1108	ABC-type Mn2 Zn2 transport systems permease components
THMIRHAT_06670	COG1121	(ABC) transporter
THMIRHAT_06700	COG0719	Fe-S assembly protein
THMIRHAT_06710	COG0396	ATPase activity
THMIRHAT_06720	COG0719	Fe-S assembly protein
THMIRHAT_06730	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
THMIRHAT_06770	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
THMIRHAT_06780	COG1181	Belongs to the D-alanine--D-alanine ligase family
THMIRHAT_06810	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
THMIRHAT_06830	COG0653	protein targeting
THMIRHAT_06850	COG0352	thiamine-phosphate diphosphorylase activity
THMIRHAT_06860	COG0237	dephospho-CoA kinase activity
THMIRHAT_06890	COG0367	asparagine synthase
THMIRHAT_06900	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
THMIRHAT_06910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
THMIRHAT_06920	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
THMIRHAT_06920	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
THMIRHAT_06930	COG0129	dihydroxy-acid dehydratase activity
THMIRHAT_06950	COG3258	Cytochrome c
THMIRHAT_06990	COG4783	chaperone-mediated protein folding
THMIRHAT_07000	COG0425	Belongs to the sulfur carrier protein TusA family
THMIRHAT_07010	COG2210	Belongs to the sulfur carrier protein TusA family
THMIRHAT_07020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
THMIRHAT_07030	COG0166	Belongs to the GPI family
THMIRHAT_07050	COG1183	phosphatidylcholine synthase activity
THMIRHAT_07060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
THMIRHAT_07080	COG0456	acetyltransferase
THMIRHAT_07090	COG1522	sequence-specific DNA binding
THMIRHAT_07100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
THMIRHAT_07140	COG1959	2 iron, 2 sulfur cluster binding
THMIRHAT_07150	COG0316	Belongs to the HesB IscA family
THMIRHAT_07160	COG0105	UTP biosynthetic process
THMIRHAT_07170	COG0820	rRNA (adenine-C2-)-methyltransferase activity
THMIRHAT_07190	COG0124	histidyl-tRNA synthetase
THMIRHAT_07210	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
THMIRHAT_07220	COG1160	GTP binding
THMIRHAT_07270	COG0446	pyridine nucleotide-disulphide oxidoreductase
THMIRHAT_07310	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
THMIRHAT_07400	COG4774	siderophore transport
THMIRHAT_07420	COG1418	mRNA catabolic process
THMIRHAT_07430	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
THMIRHAT_07440	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
THMIRHAT_07450	COG0291	Belongs to the bacterial ribosomal protein bL35 family
THMIRHAT_07460	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
THMIRHAT_07470	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
THMIRHAT_07480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
THMIRHAT_07480	COG0072	phenylalanine-tRNA ligase activity
THMIRHAT_07490	COG0776	regulation of translation
THMIRHAT_07530	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
THMIRHAT_07540	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
THMIRHAT_07550	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
THMIRHAT_07560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
THMIRHAT_07570	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
THMIRHAT_07580	COG3178	'Phosphotransferase
THMIRHAT_07590	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
THMIRHAT_07610	COG3022	response to hydroperoxide
THMIRHAT_07620	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
THMIRHAT_07630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
THMIRHAT_07640	COG0321	lipoyl(octanoyl) transferase activity
THMIRHAT_07650	COG2921	Belongs to the UPF0250 family
THMIRHAT_07670	COG1686	Belongs to the peptidase S11 family
THMIRHAT_07680	COG0772	Belongs to the SEDS family
THMIRHAT_07690	COG0768	penicillin binding
THMIRHAT_07710	COG1792	Involved in formation and maintenance of cell shape
THMIRHAT_07720	COG1077	Cell shape determining protein MreB Mrl
THMIRHAT_07730	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
THMIRHAT_07740	COG0154	amidase activity
THMIRHAT_07750	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
THMIRHAT_07760	COG2363	Small membrane protein
THMIRHAT_07770	COG0501	Belongs to the peptidase M48B family
THMIRHAT_07780	COG2166	iron-sulfur cluster assembly
THMIRHAT_07790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
THMIRHAT_07800	COG0560	Phosphoserine phosphatase
THMIRHAT_07840	COG0517	IMP dehydrogenase activity
THMIRHAT_07840	COG0516	GMP reductase activity
THMIRHAT_07850	COG0518	GMP synthase (glutamine-hydrolyzing) activity
THMIRHAT_07850	COG0519	Catalyzes the synthesis of GMP from XMP
THMIRHAT_07880	COG2801	Transposase and inactivated derivatives
THMIRHAT_07890	COG0582	viral genome integration into host DNA
THMIRHAT_07910	COG2801	Transposase and inactivated derivatives
THMIRHAT_07920	COG2801	Transposase and inactivated derivatives
THMIRHAT_07980	COG0590	tRNA wobble adenosine to inosine editing
THMIRHAT_07990	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
THMIRHAT_08000	COG0643	Histidine kinase
THMIRHAT_08000	COG2198	Histidine kinase
THMIRHAT_08030	COG0326	Molecular chaperone. Has ATPase activity
THMIRHAT_08080	COG0835	chemotaxis
THMIRHAT_08080	COG0784	Response regulator, receiver
THMIRHAT_08100	COG1815	bacterial-type flagellum-dependent cell motility
THMIRHAT_08110	COG1558	bacterial-type flagellum-dependent cell motility
THMIRHAT_08120	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
THMIRHAT_08130	COG1749	Flagellar hook protein flgE
THMIRHAT_08140	COG4786	Flagellar basal body rod
THMIRHAT_08150	COG4786	Flagellar basal body rod
THMIRHAT_08160	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
THMIRHAT_08180	COG1706	bacterial-type flagellum-dependent cell motility
THMIRHAT_08250	COG2801	Transposase and inactivated derivatives
THMIRHAT_08260	COG2801	Transposase and inactivated derivatives
THMIRHAT_08270	COG1086	Polysaccharide biosynthesis protein
THMIRHAT_08310	COG1083	cytidylyl-transferase
THMIRHAT_08360	COG1028	Short-chain dehydrogenase reductase Sdr
THMIRHAT_08380	COG2089	acid synthase
THMIRHAT_08390	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
THMIRHAT_08410	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
THMIRHAT_08480	COG4372	Transposase
THMIRHAT_08500	COG3328	transposase activity
THMIRHAT_08520	COG2244	polysaccharide biosynthetic process
THMIRHAT_08540	COG3848	Pyruvate phosphate dikinase
THMIRHAT_08540	COG0574	Belongs to the PEP-utilizing enzyme family
THMIRHAT_08550	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
THMIRHAT_08570	COG1213	nucleotidyl transferase
THMIRHAT_08610	COG1215	transferase activity, transferring glycosyl groups
THMIRHAT_08650	COG2604	Protein of unknown function DUF115
THMIRHAT_08660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
THMIRHAT_08670	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
THMIRHAT_08680	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
THMIRHAT_08690	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
THMIRHAT_08720	COG1516	flagellar protein fliS
THMIRHAT_08750	COG3852	Histidine kinase
THMIRHAT_08770	COG1677	Flagellar hook-basal body complex protein FliE
THMIRHAT_08790	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
THMIRHAT_08850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
THMIRHAT_08860	COG1360	Flagellar Motor Protein
THMIRHAT_08910	COG1338	Plays a role in the flagellum-specific transport system
THMIRHAT_08950	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
THMIRHAT_09000	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
THMIRHAT_09010	COG2198	Histidine kinase
THMIRHAT_09010	COG0643	Histidine kinase
THMIRHAT_09010	COG0784	Response regulator, receiver
THMIRHAT_09020	COG0835	chemotaxis
THMIRHAT_09030	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
THMIRHAT_09060	COG1090	epimerase
THMIRHAT_09070	COG0415	Belongs to the DNA photolyase family
THMIRHAT_09120	COG0259	pyridoxamine-phosphate oxidase activity
THMIRHAT_09150	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THMIRHAT_09160	COG1366	Belongs to the anti-sigma-factor antagonist family
THMIRHAT_09160	COG2202	Pas domain
THMIRHAT_09170	COG0789	Transcriptional regulator
THMIRHAT_09180	COG0415	Belongs to the DNA photolyase family
THMIRHAT_09210	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
THMIRHAT_09230	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
THMIRHAT_09240	COG1028	Short-chain dehydrogenase reductase Sdr
THMIRHAT_09280	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
THMIRHAT_09310	COG3118	belongs to the thioredoxin family
THMIRHAT_09330	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
THMIRHAT_09380	COG1346	cytolysis
THMIRHAT_09390	COG0205	6-phosphofructokinase activity
THMIRHAT_09400	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
THMIRHAT_09410	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
THMIRHAT_09430	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
THMIRHAT_09440	COG0343	queuine tRNA-ribosyltransferase activity
THMIRHAT_09450	COG1862	Preprotein translocase
THMIRHAT_09460	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
THMIRHAT_09470	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
THMIRHAT_09480	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
THMIRHAT_09490	COG0668	transmembrane transport
THMIRHAT_09510	COG2239	Acts as a magnesium transporter
THMIRHAT_09530	COG1137	ATPase activity
THMIRHAT_09560	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
THMIRHAT_09590	COG1127	ABC transporter
THMIRHAT_09600	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
THMIRHAT_09610	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
THMIRHAT_09640	COG1131	(ABC) transporter
THMIRHAT_09650	COG0842	Transport permease protein
THMIRHAT_09670	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
THMIRHAT_09680	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
THMIRHAT_09690	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
THMIRHAT_09700	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
THMIRHAT_09710	COG0723	plastoquinol--plastocyanin reductase activity
THMIRHAT_09720	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
THMIRHAT_09730	COG2857	Cytochrome c1
THMIRHAT_09740	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
THMIRHAT_09750	COG0784	Response regulator, receiver
THMIRHAT_09750	COG5002	protein histidine kinase activity
THMIRHAT_09750	COG2198	Histidine kinase
THMIRHAT_09770	COG4536	flavin adenine dinucleotide binding
THMIRHAT_09800	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
THMIRHAT_09820	COG1051	belongs to the nudix hydrolase family
THMIRHAT_09840	COG0508	dehydrogenase complex catalyzes the overall conversion of
THMIRHAT_09850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
THMIRHAT_09870	COG0513	Belongs to the DEAD box helicase family
THMIRHAT_09880	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
THMIRHAT_09890	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
THMIRHAT_09900	COG0513	Belongs to the DEAD box helicase family
THMIRHAT_09950	COG0564	pseudouridine synthase activity
THMIRHAT_09990	COG4095	Psort location CytoplasmicMembrane, score
THMIRHAT_10000	COG1280	lysine exporter protein (LysE YggA)
THMIRHAT_10010	COG1902	pentaerythritol trinitrate reductase activity
THMIRHAT_10030	COG1720	tRNA m6t6A37 methyltransferase activity
THMIRHAT_10050	COG1741	Belongs to the pirin family
THMIRHAT_10060	COG0583	DNA-binding transcription factor activity
THMIRHAT_10090	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
THMIRHAT_10100	COG0420	3'-5' exonuclease activity
THMIRHAT_10110	COG0419	ATPase involved in DNA repair
THMIRHAT_10190	COG3300	MHYT domain
THMIRHAT_10190	COG5001	Diguanylate cyclase
THMIRHAT_10200	COG0488	(ABC) transporter
THMIRHAT_10210	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
THMIRHAT_10220	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
THMIRHAT_10230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
THMIRHAT_10230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
THMIRHAT_10260	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
THMIRHAT_10270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
THMIRHAT_10280	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
THMIRHAT_10290	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
THMIRHAT_10310	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
THMIRHAT_10330	COG0720	synthase
THMIRHAT_10340	COG0142	geranyltranstransferase activity
THMIRHAT_10350	COG0450	alkyl hydroperoxide reductase
THMIRHAT_10380	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
THMIRHAT_10400	COG0784	Response regulator, receiver
THMIRHAT_10400	COG2205	protein histidine kinase activity
THMIRHAT_10420	COG2801	Transposase and inactivated derivatives
THMIRHAT_10430	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
THMIRHAT_10470	COG0745	RESPONSE REGULATOR receiver
THMIRHAT_10480	COG0835	chemotaxis
THMIRHAT_10510	COG2201	protein-glutamate methylesterase activity
THMIRHAT_10560	COG0492	ferredoxin-NADP+ reductase activity
THMIRHAT_10570	COG1674	ftsk spoiiie
THMIRHAT_10580	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
THMIRHAT_10590	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
THMIRHAT_10600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
THMIRHAT_10610	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
THMIRHAT_10630	COG1546	Belongs to the CinA family
THMIRHAT_10640	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
THMIRHAT_10660	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
THMIRHAT_10700	COG4221	oxidoreductase activity
THMIRHAT_10730	COG0564	pseudouridine synthase activity
THMIRHAT_10740	COG2983	Belongs to the UPF0260 family
THMIRHAT_10760	COG0243	molybdopterin cofactor binding
THMIRHAT_10830	COG0489	protein tyrosine kinase activity
THMIRHAT_10850	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
THMIRHAT_10950	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
THMIRHAT_10970	COG2205	protein histidine kinase activity
THMIRHAT_10980	COG0745	RESPONSE REGULATOR receiver
THMIRHAT_11010	COG3300	MHYT domain
THMIRHAT_11010	COG5001	Diguanylate cyclase
THMIRHAT_11030	COG0848	biopolymer transport protein
THMIRHAT_11040	COG0811	peptide transport
THMIRHAT_11060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THMIRHAT_11110	COG0446	pyridine nucleotide-disulphide oxidoreductase
THMIRHAT_11140	COG0574	Belongs to the PEP-utilizing enzyme family
THMIRHAT_11140	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
THMIRHAT_11150	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
THMIRHAT_11160	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THMIRHAT_11200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
THMIRHAT_11210	COG4660	Part of a membrane complex involved in electron transport
THMIRHAT_11220	COG4659	FMN binding
THMIRHAT_11240	COG4656	Part of a membrane complex involved in electron transport
THMIRHAT_11250	COG2878	Part of a membrane complex involved in electron transport
THMIRHAT_11260	COG4657	Part of a membrane complex involved in electron transport
THMIRHAT_11270	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
THMIRHAT_11270	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
THMIRHAT_11300	COG0564	pseudouridine synthase activity
THMIRHAT_11320	COG0489	protein tyrosine kinase activity
THMIRHAT_11330	COG0717	Belongs to the dCTP deaminase family
THMIRHAT_11350	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
THMIRHAT_11360	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
THMIRHAT_11380	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
THMIRHAT_11390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
THMIRHAT_11460	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
THMIRHAT_11470	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
THMIRHAT_11500	COG1115	amino acid carrier protein
THMIRHAT_11520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
THMIRHAT_11540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
THMIRHAT_11560	COG0545	Peptidyl-prolyl cis-trans isomerase
THMIRHAT_11580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
THMIRHAT_11590	COG0442	prolyl-tRNA aminoacylation
THMIRHAT_11620	COG0232	Belongs to the dGTPase family. Type 2 subfamily
THMIRHAT_11630	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
THMIRHAT_11650	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
THMIRHAT_11660	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
THMIRHAT_11700	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
THMIRHAT_11710	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
THMIRHAT_11740	COG0006	proline dipeptidase activity
THMIRHAT_11750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
THMIRHAT_11760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
THMIRHAT_11770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
THMIRHAT_11780	COG0583	DNA-binding transcription factor activity
THMIRHAT_11790	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
THMIRHAT_11800	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THMIRHAT_11810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
THMIRHAT_11830	COG0047	phosphoribosylformylglycinamidine synthase activity
THMIRHAT_11830	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
THMIRHAT_11850	COG0322	excinuclease ABC activity
THMIRHAT_11860	COG0667	Aldo Keto reductase
THMIRHAT_11910	COG0837	glucose binding
THMIRHAT_11930	COG3657	addiction module killer protein
THMIRHAT_11980	COG3604	Transcriptional regulator
THMIRHAT_11990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
THMIRHAT_12000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
THMIRHAT_12010	COG1116	anion transmembrane transporter activity
THMIRHAT_12020	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
THMIRHAT_12060	COG2199	diguanylate cyclase activity
THMIRHAT_12060	COG2202	Pas domain
THMIRHAT_12060	COG2200	EAL domain
THMIRHAT_12090	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
THMIRHAT_12110	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
THMIRHAT_12120	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
THMIRHAT_12130	COG0354	folic acid binding
THMIRHAT_12140	COG0835	chemotaxis
THMIRHAT_12170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
THMIRHAT_12180	COG0481	GTPase activity
THMIRHAT_12200	COG0571	ribonuclease III activity
THMIRHAT_12220	COG1381	Involved in DNA repair and RecF pathway recombination
THMIRHAT_12230	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
THMIRHAT_12240	COG0736	holo-[acyl-carrier-protein] synthase activity
THMIRHAT_12310	COG3706	GGDEF domain
THMIRHAT_12320	COG1047	Peptidyl-prolyl cis-trans
THMIRHAT_12340	COG0045	succinate-CoA ligase (ADP-forming) activity
THMIRHAT_12360	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
THMIRHAT_12360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
THMIRHAT_12390	COG3023	N-Acetylmuramoyl-L-alanine amidase
THMIRHAT_12400	COG0716	FMN binding
THMIRHAT_12410	COG2161	toxin-antitoxin pair type II binding
THMIRHAT_12420	COG4115	mRNA cleavage
THMIRHAT_12430	COG1643	Atp-dependent helicase
THMIRHAT_12470	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
THMIRHAT_12480	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
THMIRHAT_12500	COG1376	ErfK ybiS ycfS ynhG family protein
THMIRHAT_12510	COG0601	transmembrane transport
THMIRHAT_12540	COG1472	Belongs to the glycosyl hydrolase 3 family
THMIRHAT_12550	COG0668	transmembrane transport
THMIRHAT_12570	COG0733	neurotransmitter:sodium symporter activity
THMIRHAT_12600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
THMIRHAT_12610	COG1393	Belongs to the ArsC family
THMIRHAT_12620	COG2171	N-acyltransferase activity
THMIRHAT_12630	COG0346	lactoylglutathione lyase activity
THMIRHAT_12680	COG3706	GGDEF domain
THMIRHAT_12710	COG1403	HNH endonuclease
THMIRHAT_12720	COG1525	nuclease
THMIRHAT_12830	COG0322	excinuclease ABC activity
THMIRHAT_12840	COG0616	signal peptide processing
THMIRHAT_12860	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
THMIRHAT_12880	COG0446	pyridine nucleotide-disulphide oxidoreductase
THMIRHAT_12910	COG1136	(ABC) transporter
THMIRHAT_12920	COG0488	(ABC) transporter
THMIRHAT_12930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
THMIRHAT_12940	COG0544	peptidyl-prolyl cis-trans isomerase activity
THMIRHAT_12950	COG0740	serine-type endopeptidase activity
THMIRHAT_12960	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
THMIRHAT_12970	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
THMIRHAT_13010	COG0601	transmembrane transport
THMIRHAT_13020	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
THMIRHAT_13040	COG2827	Endonuclease containing a URI domain
THMIRHAT_13060	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
THMIRHAT_13070	COG1570	exodeoxyribonuclease VII activity
THMIRHAT_13090	COG1393	Belongs to the ArsC family
THMIRHAT_13120	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
THMIRHAT_13140	COG0745	RESPONSE REGULATOR receiver
THMIRHAT_13180	COG3012	SEC-C Motif Domain Protein
THMIRHAT_13210	COG0494	nUDIX hydrolase
THMIRHAT_13220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
THMIRHAT_13240	COG0359	binds to the 23S rRNA
THMIRHAT_13260	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
THMIRHAT_13270	COG0360	Binds together with S18 to 16S ribosomal RNA
THMIRHAT_13280	COG0284	orotidine-5'-phosphate decarboxylase activity
THMIRHAT_13300	COG0776	regulation of translation
THMIRHAT_13330	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
THMIRHAT_13340	COG0287	Prephenate dehydrogenase
THMIRHAT_13350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
THMIRHAT_13360	COG0077	Prephenate dehydratase
THMIRHAT_13360	COG1605	Chorismate mutase
THMIRHAT_13370	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
THMIRHAT_13390	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
THMIRHAT_13410	COG1028	Short-chain dehydrogenase reductase Sdr
THMIRHAT_13430	COG1185	polyribonucleotide nucleotidyltransferase activity
THMIRHAT_13440	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
THMIRHAT_13460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
THMIRHAT_13470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
THMIRHAT_13480	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
THMIRHAT_13490	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
THMIRHAT_13500	COG0195	Participates in both transcription termination and antitermination
THMIRHAT_13500	COG2251	uridine kinase activity
THMIRHAT_13510	COG0779	Required for maturation of 30S ribosomal subunits
THMIRHAT_13550	COG3162	membrane
THMIRHAT_13560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
THMIRHAT_13580	COG0747	negative chemotaxis
THMIRHAT_13600	COG2954	triphosphatase activity
THMIRHAT_13660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
THMIRHAT_13700	COG4206	TonB-dependent receptor
THMIRHAT_13710	COG1492	cobalamin metabolic process
THMIRHAT_13780	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
THMIRHAT_13790	COG2835	tetraacyldisaccharide 4'-kinase activity
THMIRHAT_13800	COG1663	tetraacyldisaccharide 4'-kinase activity
THMIRHAT_13810	COG2333	competence protein COMEC
THMIRHAT_13810	COG0658	competence protein
THMIRHAT_13830	COG1067	ATP-dependent peptidase activity
THMIRHAT_13840	COG0004	ammonium transporteR
THMIRHAT_13870	COG0037	tRNA processing
THMIRHAT_13870	COG0590	tRNA wobble adenosine to inosine editing
THMIRHAT_13880	COG0835	chemotaxis
THMIRHAT_13880	COG0784	Response regulator, receiver
THMIRHAT_13890	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
THMIRHAT_13900	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
THMIRHAT_13910	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
THMIRHAT_13920	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
THMIRHAT_13930	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
THMIRHAT_13950	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
THMIRHAT_13960	COG0750	zinc metalloprotease
THMIRHAT_13970	COG0575	Belongs to the CDS family
THMIRHAT_13990	COG0233	cytoplasmic translational termination
THMIRHAT_14000	COG0528	UMP kinase activity
THMIRHAT_14010	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
THMIRHAT_14020	COG0052	Belongs to the universal ribosomal protein uS2 family
THMIRHAT_14030	COG0024	Methionine aminopeptidase
THMIRHAT_14040	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
THMIRHAT_14060	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
THMIRHAT_14070	COG2894	cell division
THMIRHAT_14090	COG1049	propionate catabolic process, 2-methylcitrate cycle
THMIRHAT_14140	COG2850	peptidyl-arginine hydroxylation
THMIRHAT_14150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
THMIRHAT_14160	COG0363	glucosamine-6-phosphate deaminase activity
THMIRHAT_14170	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
THMIRHAT_14180	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
THMIRHAT_14190	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
THMIRHAT_14220	COG2900	Belongs to the SlyX family
THMIRHAT_14230	COG0840	transmembrane signaling receptor activity
THMIRHAT_14250	COG1994	Peptidase M50
THMIRHAT_14260	COG0009	L-threonylcarbamoyladenylate synthase
THMIRHAT_14280	COG2205	protein histidine kinase activity
THMIRHAT_14280	COG0784	Response regulator, receiver
THMIRHAT_14290	COG0613	PHP domain protein
THMIRHAT_14300	COG2917	probably involved in intracellular septation
THMIRHAT_14310	COG2350	Protein conserved in bacteria
THMIRHAT_14320	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
THMIRHAT_14340	COG0697	spore germination
THMIRHAT_14360	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
THMIRHAT_14370	COG3115	cell septum assembly
THMIRHAT_14380	COG1070	Carbohydrate kinase
THMIRHAT_14390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
THMIRHAT_14400	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
THMIRHAT_14470	COG1643	Atp-dependent helicase
THMIRHAT_14500	COG2204	response regulator
THMIRHAT_14510	COG3852	Histidine kinase
THMIRHAT_14550	COG1929	Belongs to the glycerate kinase type-1 family
THMIRHAT_14580	COG2308	Evidence 4 Homologs of previously reported genes of
THMIRHAT_14600	COG1215	transferase activity, transferring glycosyl groups
THMIRHAT_14620	COG0477	Major facilitator Superfamily
THMIRHAT_14630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
THMIRHAT_14650	COG0456	acetyltransferase
THMIRHAT_14660	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
THMIRHAT_14670	COG1917	Cupin 2, conserved barrel domain protein
THMIRHAT_14700	COG0840	transmembrane signaling receptor activity
THMIRHAT_14700	COG0840	transmembrane signaling receptor activity
THMIRHAT_14710	COG2199	diguanylate cyclase activity
THMIRHAT_14710	COG2200	EAL domain
THMIRHAT_14720	COG1116	anion transmembrane transporter activity
THMIRHAT_14740	COG1116	anion transmembrane transporter activity
THMIRHAT_14740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
THMIRHAT_14750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
THMIRHAT_14750	COG1116	anion transmembrane transporter activity
THMIRHAT_14770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
THMIRHAT_14780	COG1648	precorrin-2 dehydrogenase activity
THMIRHAT_14780	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
THMIRHAT_14790	COG0243	molybdopterin cofactor binding
THMIRHAT_14800	COG0840	transmembrane signaling receptor activity
THMIRHAT_14800	COG0840	transmembrane signaling receptor activity
THMIRHAT_14810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
THMIRHAT_14810	COG2146	nitrite reductase [NAD(P)H] activity
THMIRHAT_14820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
THMIRHAT_14830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
THMIRHAT_14850	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
THMIRHAT_14860	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
THMIRHAT_14880	COG0823	Involved in the tonB-independent uptake of proteins
THMIRHAT_14920	COG2255	four-way junction helicase activity
THMIRHAT_14930	COG0632	four-way junction helicase activity
THMIRHAT_14940	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
THMIRHAT_14950	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
THMIRHAT_14960	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
THMIRHAT_14980	COG0300	oxidoreductase activity
THMIRHAT_14990	COG1752	Esterase of the alpha-beta hydrolase superfamily
THMIRHAT_15010	COG1116	anion transmembrane transporter activity
THMIRHAT_15010	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
THMIRHAT_15030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
THMIRHAT_15060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
THMIRHAT_15090	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
THMIRHAT_15110	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
THMIRHAT_15130	COG0436	Aminotransferase
THMIRHAT_15160	COG1238	metal cluster binding
THMIRHAT_15170	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
THMIRHAT_15180	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
THMIRHAT_15190	COG2840	Smr protein MutS2
THMIRHAT_15200	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
THMIRHAT_15210	COG0148	phosphopyruvate hydratase activity
THMIRHAT_15220	COG2877	3-deoxy-8-phosphooctulonate synthase activity
THMIRHAT_15230	COG0504	CTP synthase activity
THMIRHAT_15240	COG0037	tRNA processing
THMIRHAT_15250	COG0825	malonyl-CoA metabolic process
THMIRHAT_15260	COG1944	ATP diphosphatase activity
THMIRHAT_15300	COG1199	ATP-dependent helicase activity
THMIRHAT_15310	COG0542	response to heat
THMIRHAT_15320	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
THMIRHAT_15330	COG0484	heat shock protein binding
THMIRHAT_15340	COG2824	Alkylphosphonate utilization operon protein PhnA
THMIRHAT_15370	COG2996	Protein conserved in bacteria
THMIRHAT_15400	COG1187	pseudouridine synthase activity
THMIRHAT_15410	COG0482	sulfurtransferase activity
THMIRHAT_15420	COG2915	High frequency lysogenization protein hflD homolog
THMIRHAT_15440	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
THMIRHAT_15450	COG0745	RESPONSE REGULATOR receiver
THMIRHAT_15460	COG0840	transmembrane signaling receptor activity
THMIRHAT_15480	COG1132	(ABC) transporter
THMIRHAT_15490	COG0084	hydrolase, TatD family'
THMIRHAT_15500	COG0470	DNA polymerase III
THMIRHAT_15510	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
THMIRHAT_15520	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
THMIRHAT_15530	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
THMIRHAT_15540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
THMIRHAT_15550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
THMIRHAT_15560	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
THMIRHAT_15580	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
THMIRHAT_15590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
THMIRHAT_15600	COG0416	fatty acid biosynthetic process
THMIRHAT_15610	COG0333	Belongs to the bacterial ribosomal protein bL32 family
THMIRHAT_15630	COG0424	maF-like protein
THMIRHAT_15650	COG0564	pseudouridine synthase activity
THMIRHAT_15660	COG1530	ribonuclease E activity
THMIRHAT_15670	COG0215	cysteine-tRNA ligase activity
THMIRHAT_15690	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
THMIRHAT_15710	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
THMIRHAT_15740	COG1301	dicarboxylic acid transport
THMIRHAT_15750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
THMIRHAT_15760	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
THMIRHAT_15770	COG0137	argininosuccinate synthase activity
THMIRHAT_15780	COG0688	phosphatidylethanolamine metabolic process
THMIRHAT_15790	COG0347	Belongs to the P(II) protein family
THMIRHAT_15800	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
THMIRHAT_15810	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
THMIRHAT_15820	COG0330	HflC and HflK could
THMIRHAT_15830	COG0330	HflC and HflK could
THMIRHAT_15840	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
THMIRHAT_15850	COG1923	regulation of RNA biosynthetic process
THMIRHAT_15860	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
THMIRHAT_15870	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
THMIRHAT_15890	COG0802	atpase or kinase
THMIRHAT_15990	COG1940	carbohydrate kinase activity
THMIRHAT_16010	COG2833	Protein of unknown function (DUF455)
THMIRHAT_16030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
THMIRHAT_16050	COG0505	Belongs to the CarA family
THMIRHAT_16080	COG4628	conserved protein (DUF2132)
THMIRHAT_16100	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
THMIRHAT_16110	COG0484	heat shock protein binding
THMIRHAT_16120	COG0443	Heat shock 70 kDa protein
THMIRHAT_16130	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
THMIRHAT_16140	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
THMIRHAT_16150	COG0497	DNA recombination
THMIRHAT_16180	COG0735	belongs to the Fur family
THMIRHAT_16200	COG2914	Belongs to the UPF0125 (RnfH) family
THMIRHAT_16210	COG2867	negative regulation of translational initiation
THMIRHAT_16220	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
THMIRHAT_16230	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
THMIRHAT_16250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
THMIRHAT_16270	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
THMIRHAT_16300	COG2186	Transcriptional regulator
THMIRHAT_16310	COG2351	hydroxyisourate hydrolase activity
THMIRHAT_16320	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
THMIRHAT_16330	COG1529	Aldehyde oxidase and xanthine dehydrogenase
THMIRHAT_16340	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
THMIRHAT_16340	COG3608	succinylglutamate desuccinylase aspartoacylase
THMIRHAT_16350	COG0590	tRNA wobble adenosine to inosine editing
THMIRHAT_16410	COG1116	anion transmembrane transporter activity
THMIRHAT_16420	COG0864	Transcriptional regulator
THMIRHAT_16440	COG3665	Urea carboxylase-associated protein
THMIRHAT_16450	COG0439	Biotin carboxylase
THMIRHAT_16510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
THMIRHAT_16550	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
THMIRHAT_16570	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
THMIRHAT_16580	COG0730	response to heat
THMIRHAT_16600	COG0154	amidase activity
THMIRHAT_16610	COG1047	Peptidyl-prolyl cis-trans
THMIRHAT_16620	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
THMIRHAT_16630	COG3706	GGDEF domain
THMIRHAT_16640	COG2801	Transposase and inactivated derivatives
THMIRHAT_16650	COG0328	RNA-DNA hybrid ribonuclease activity
THMIRHAT_16660	COG2226	methyltransferase
THMIRHAT_16670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
THMIRHAT_16680	COG0741	lytic transglycosylase activity
THMIRHAT_16680	COG1388	LysM domain
THMIRHAT_16700	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
THMIRHAT_16710	COG0564	pseudouridine synthase activity
THMIRHAT_16750	COG1007	ATP synthesis coupled electron transport
THMIRHAT_16780	COG0713	ATP synthesis coupled electron transport
THMIRHAT_16800	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THMIRHAT_16810	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
THMIRHAT_16820	COG1034	ATP synthesis coupled electron transport
THMIRHAT_16840	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
THMIRHAT_16850	COG0649	NAD binding
THMIRHAT_16860	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THMIRHAT_16870	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THMIRHAT_16880	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
THMIRHAT_16900	COG0149	triose-phosphate isomerase activity
THMIRHAT_16910	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
THMIRHAT_16920	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
THMIRHAT_16940	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
THMIRHAT_16950	COG1534	Rna-binding protein
THMIRHAT_16990	COG0285	dihydrofolate synthase activity
THMIRHAT_17000	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
THMIRHAT_17010	COG0159	tryptophan synthase activity
THMIRHAT_17030	COG0135	phosphoribosylanthranilate isomerase activity
THMIRHAT_17040	COG0101	tRNA pseudouridine synthase activity
THMIRHAT_17050	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
THMIRHAT_17070	COG0739	heme binding
THMIRHAT_17080	COG0473	3-isopropylmalate dehydrogenase activity
THMIRHAT_17100	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
THMIRHAT_17110	COG0602	queuosine metabolic process
THMIRHAT_17120	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
THMIRHAT_17150	COG0189	ligase activity
THMIRHAT_17180	COG2239	Acts as a magnesium transporter
THMIRHAT_17190	COG1253	flavin adenine dinucleotide binding
THMIRHAT_17230	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
THMIRHAT_17230	COG3264	Mechanosensitive ion channel
THMIRHAT_17240	COG0189	ligase activity
THMIRHAT_17260	COG0189	ligase activity
THMIRHAT_17260	COG4067	protein conserved in archaea
THMIRHAT_17280	COG0668	transmembrane transport
THMIRHAT_17310	COG0488	(ABC) transporter
THMIRHAT_17320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
THMIRHAT_17390	COG0308	aminopeptidase N
THMIRHAT_17400	COG2885	chlorophyll binding
THMIRHAT_17410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
THMIRHAT_17450	COG0557	exoribonuclease II activity
THMIRHAT_17460	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
THMIRHAT_17470	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
THMIRHAT_17490	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
THMIRHAT_17500	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
THMIRHAT_17510	COG2814	Major facilitator Superfamily
THMIRHAT_17520	COG0659	secondary active sulfate transmembrane transporter activity
THMIRHAT_17540	COG3123	guanosine phosphorylase activity
THMIRHAT_17570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
THMIRHAT_17590	COG2353	YceI-like domain
THMIRHAT_17600	COG3038	cytochrome b561
THMIRHAT_17620	COG2873	o-acetylhomoserine
THMIRHAT_17640	COG2814	Major facilitator Superfamily
THMIRHAT_17660	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
THMIRHAT_17680	COG0268	Binds directly to 16S ribosomal RNA
THMIRHAT_17700	COG1671	Belongs to the UPF0178 family
THMIRHAT_17710	COG0247	lactate metabolic process
THMIRHAT_17710	COG0277	FAD linked oxidase domain protein
THMIRHAT_17720	COG0463	Glycosyl transferase, family 2
THMIRHAT_17750	COG2990	Protein conserved in bacteria
THMIRHAT_17770	COG0859	PFAM glycosyl transferase family 9
THMIRHAT_17780	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
THMIRHAT_17800	COG1132	(ABC) transporter
THMIRHAT_17810	COG1560	Kdo2-lipid A biosynthetic process
THMIRHAT_17820	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
THMIRHAT_17830	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
THMIRHAT_17840	COG1360	Flagellar Motor Protein
THMIRHAT_17850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
THMIRHAT_17860	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
THMIRHAT_17870	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
THMIRHAT_17880	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
THMIRHAT_17890	COG0617	tRNA 3'-terminal CCA addition
THMIRHAT_17950	COG0004	ammonium transporteR
THMIRHAT_17970	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
THMIRHAT_17980	COG0525	valine-tRNA ligase activity
THMIRHAT_17990	COG4991	sh3 domain protein
THMIRHAT_18000	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
THMIRHAT_18020	COG0335	large ribosomal subunit rRNA binding
THMIRHAT_18030	COG0336	Belongs to the RNA methyltransferase TrmD family
THMIRHAT_18040	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
THMIRHAT_18050	COG0228	four-way junction DNA binding
THMIRHAT_18060	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
THMIRHAT_18080	COG0028	Belongs to the TPP enzyme family
THMIRHAT_18090	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
THMIRHAT_18100	COG0501	Belongs to the peptidase M48B family
THMIRHAT_18110	COG2154	pterin-4-alpha-carbinolamine dehydratase
THMIRHAT_18120	COG1162	GTPase activity
THMIRHAT_18240	COG3267	Type II secretory pathway component ExeA
THMIRHAT_18240	COG3409	Peptidoglycan-binding domain 1 protein
THMIRHAT_18270	COG1530	ribonuclease E activity
THMIRHAT_18280	COG0424	maF-like protein
THMIRHAT_18290	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THMIRHAT_18310	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
THMIRHAT_18320	COG0799	negative regulation of ribosome biogenesis
THMIRHAT_18330	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
THMIRHAT_18350	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
THMIRHAT_18380	COG0495	leucyl-tRNA aminoacylation
THMIRHAT_18400	COG0815	Transfers the fatty acyl group on membrane lipoproteins
THMIRHAT_18410	COG4535	Mg2 and Co2 transporter CorC
THMIRHAT_18420	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
THMIRHAT_18430	COG1702	phosphate starvation-inducible protein PhoH
THMIRHAT_18440	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
THMIRHAT_18450	COG0840	transmembrane signaling receptor activity
THMIRHAT_18460	COG3338	carbonate dehydratase activity
THMIRHAT_18480	COG0521	Mo-molybdopterin cofactor biosynthetic process
THMIRHAT_18490	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
THMIRHAT_18520	COG4251	negative regulation of phosphorylation
THMIRHAT_18550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
THMIRHAT_18560	COG0271	Belongs to the BolA IbaG family
THMIRHAT_18590	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
THMIRHAT_18600	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
THMIRHAT_18610	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
THMIRHAT_18620	COG0583	DNA-binding transcription factor activity
THMIRHAT_18640	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
THMIRHAT_18780	COG2239	Acts as a magnesium transporter
THMIRHAT_18800	COG3002	Belongs to the UPF0753 family
THMIRHAT_18810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
THMIRHAT_18840	COG0494	nUDIX hydrolase
THMIRHAT_18850	COG1011	Hydrolase
THMIRHAT_18920	COG0500	methyltransferase
THMIRHAT_18940	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
THMIRHAT_18960	COG1178	ABC-type Fe3 transport system permease component
THMIRHAT_18980	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
THMIRHAT_18990	COG0433	COG0433 Predicted ATPase
THMIRHAT_19010	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
THMIRHAT_19020	COG0588	phosphoglycerate mutase activity
THMIRHAT_19080	COG1120	ATPase activity
THMIRHAT_19090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
THMIRHAT_19100	COG1295	ribonuclease BN
THMIRHAT_19130	COG0693	protein deglycase activity
THMIRHAT_19140	COG0793	Belongs to the peptidase S41A family
THMIRHAT_19150	COG0640	Transcriptional regulator
THMIRHAT_19180	COG1850	ribulose-bisphosphate carboxylase activity
THMIRHAT_19210	COG0288	reversible hydration of carbon dioxide
THMIRHAT_19240	COG2391	methyltransferase activity
THMIRHAT_19250	COG0446	pyridine nucleotide-disulphide oxidoreductase
THMIRHAT_19270	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
THMIRHAT_19300	COG1131	(ABC) transporter
THMIRHAT_19310	COG2223	nitrite transmembrane transporter activity
THMIRHAT_19320	COG0542	response to heat
THMIRHAT_19350	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
THMIRHAT_19360	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
THMIRHAT_19400	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
THMIRHAT_19430	COG3328	transposase activity
THMIRHAT_19440	COG0659	secondary active sulfate transmembrane transporter activity
THMIRHAT_19450	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
THMIRHAT_19470	COG2226	methyltransferase
THMIRHAT_19490	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
THMIRHAT_19510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
THMIRHAT_19530	COG0840	transmembrane signaling receptor activity
THMIRHAT_19570	COG0012	GTP binding
THMIRHAT_19580	COG0193	aminoacyl-tRNA hydrolase activity
THMIRHAT_19590	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
THMIRHAT_19600	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
THMIRHAT_19620	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
THMIRHAT_19630	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
THMIRHAT_19640	COG2890	protein-(glutamine-N5) methyltransferase activity
THMIRHAT_19650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
THMIRHAT_19670	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
THMIRHAT_19730	COG0259	pyridoxamine-phosphate oxidase activity
THMIRHAT_19750	COG0840	transmembrane signaling receptor activity
THMIRHAT_19810	COG0751	glycine-tRNA ligase activity
THMIRHAT_19830	COG0425	Belongs to the sulfur carrier protein TusA family
THMIRHAT_19830	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
THMIRHAT_19840	COG0739	heme binding
THMIRHAT_19850	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
THMIRHAT_19870	COG0316	Belongs to the HesB IscA family
THMIRHAT_19880	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
THMIRHAT_19980	COG2197	response regulator
THMIRHAT_20000	COG0606	chelatase, subunit chli
THMIRHAT_20020	COG3706	GGDEF domain
THMIRHAT_20040	COG0018	arginyl-trna synthetase
THMIRHAT_20060	COG4566	intracellular signal transduction
THMIRHAT_20070	COG0758	DNA mediated transformation
THMIRHAT_20080	COG0242	peptide deformylase activity
THMIRHAT_20090	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
THMIRHAT_20120	COG5000	phosphorelay sensor kinase activity
THMIRHAT_20130	COG2204	response regulator
THMIRHAT_20140	COG0569	domain protein
THMIRHAT_20150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
THMIRHAT_20230	COG0037	tRNA processing
THMIRHAT_20260	COG1555	photosystem II stabilization
THMIRHAT_20260	COG1596	polysaccharide export
THMIRHAT_20270	COG2258	MOSC domain
THMIRHAT_20290	COG0730	response to heat
THMIRHAT_20300	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
THMIRHAT_20310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
THMIRHAT_20420	COG0582	viral genome integration into host DNA
THMIRHAT_20440	COG3328	transposase activity
THMIRHAT_20490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
THMIRHAT_20490	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
THMIRHAT_20550	COG0438	transferase activity, transferring glycosyl groups
THMIRHAT_20550	COG1216	Glycosyl transferase, family 2
THMIRHAT_20560	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
THMIRHAT_20640	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
THMIRHAT_20650	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
THMIRHAT_20660	COG1410	methionine synthase
THMIRHAT_20660	COG0646	methionine synthase
THMIRHAT_20680	COG1708	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity
THMIRHAT_20790	COG0315	cyclic pyranopterin monophosphate synthase activity
THMIRHAT_20800	COG0303	'Molybdopterin
THMIRHAT_20810	COG0314	molybdopterin synthase activity
THMIRHAT_20820	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
THMIRHAT_20830	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
THMIRHAT_20860	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
THMIRHAT_20890	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
THMIRHAT_20900	COG2203	Gaf domain
THMIRHAT_20900	COG3706	GGDEF domain
THMIRHAT_20900	COG4251	negative regulation of phosphorylation
THMIRHAT_20900	COG5001	Diguanylate cyclase
THMIRHAT_20910	COG0543	2 iron, 2 sulfur cluster binding
THMIRHAT_20910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
THMIRHAT_20920	COG0708	Exodeoxyribonuclease III
THMIRHAT_20950	COG1136	(ABC) transporter
THMIRHAT_20960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
THMIRHAT_20960	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
THMIRHAT_20980	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
THMIRHAT_21000	COG5002	protein histidine kinase activity
THMIRHAT_21000	COG2205	protein histidine kinase activity
THMIRHAT_21000	COG0784	Response regulator, receiver
THMIRHAT_21020	COG2081	HI0933 family
THMIRHAT_21040	COG0678	peroxiredoxin activity
THMIRHAT_21040	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
THMIRHAT_21060	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
THMIRHAT_21100	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
THMIRHAT_21110	COG1561	YicC-like family, N-terminal region
THMIRHAT_21140	COG3001	Fructosamine kinase
THMIRHAT_21150	COG0563	adenylate kinase activity
THMIRHAT_21160	COG3706	GGDEF domain
THMIRHAT_21190	COG4181	ATPase activity
THMIRHAT_21200	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
THMIRHAT_21290	COG2200	EAL domain
THMIRHAT_21320	COG0596	Alpha beta hydrolase
THMIRHAT_21380	COG1850	ribulose-bisphosphate carboxylase activity
THMIRHAT_21390	COG0583	DNA-binding transcription factor activity
THMIRHAT_21400	COG0840	transmembrane signaling receptor activity
THMIRHAT_21420	COG2205	protein histidine kinase activity
THMIRHAT_21420	COG0784	Response regulator, receiver
THMIRHAT_21440	COG2199	diguanylate cyclase activity
THMIRHAT_21440	COG2200	EAL domain
THMIRHAT_21440	COG3287	FIST C domain
THMIRHAT_21450	COG4251	negative regulation of phosphorylation
THMIRHAT_21450	COG3706	GGDEF domain
THMIRHAT_21450	COG5001	Diguanylate cyclase
THMIRHAT_21450	COG2203	Gaf domain
THMIRHAT_21470	COG2814	Major facilitator Superfamily
THMIRHAT_21540	COG4206	TonB-dependent receptor
THMIRHAT_21570	COG0840	transmembrane signaling receptor activity
THMIRHAT_21650	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
THMIRHAT_21660	COG0697	spore germination
THMIRHAT_21670	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
THMIRHAT_21740	COG0390	transport system, permease component
THMIRHAT_21760	COG3040	lipid binding
THMIRHAT_21770	COG4335	DNA alkylation repair
THMIRHAT_21780	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
THMIRHAT_21790	COG0277	FAD linked oxidase domain protein
THMIRHAT_21800	COG0277	FAD linked oxidase domain protein
THMIRHAT_21810	COG0247	lactate metabolic process
THMIRHAT_21820	COG2759	Belongs to the formate--tetrahydrofolate ligase family
THMIRHAT_21830	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
THMIRHAT_21880	COG1262	PFAM Formylglycine-generating sulfatase enzyme
THMIRHAT_21890	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
THMIRHAT_21900	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
THMIRHAT_21910	COG3842	ATPase activity
THMIRHAT_21920	COG1176	ABC-type spermidine putrescine transport system, permease component I
THMIRHAT_21930	COG1177	transmembrane transport
THMIRHAT_21970	COG3437	response regulator, receiver
THMIRHAT_21970	COG0784	Response regulator, receiver
THMIRHAT_22020	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
THMIRHAT_22080	COG1854	S-ribosylhomocysteine lyase activity
THMIRHAT_22090	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
THMIRHAT_22100	COG0840	transmembrane signaling receptor activity
THMIRHAT_22110	COG5001	Diguanylate cyclase
THMIRHAT_22110	COG3300	MHYT domain
THMIRHAT_22130	COG5002	protein histidine kinase activity
THMIRHAT_22130	COG5001	Diguanylate cyclase
THMIRHAT_22150	COG1444	tRNA N-acetyltransferase activity
THMIRHAT_22160	COG0788	formyltetrahydrofolate deformylase activity
THMIRHAT_22180	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
THMIRHAT_22190	COG0254	rRNA binding
THMIRHAT_22210	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
THMIRHAT_22220	COG0328	RNA-DNA hybrid ribonuclease activity
THMIRHAT_22250	COG0561	phosphatase activity
THMIRHAT_22250	COG3100	YcgL domain-containing protein
THMIRHAT_22260	COG0438	transferase activity, transferring glycosyl groups
THMIRHAT_22300	COG0489	protein tyrosine kinase activity
THMIRHAT_22350	COG0463	Glycosyl transferase, family 2
THMIRHAT_22380	COG0297	glycogen (starch) synthase activity
THMIRHAT_22400	COG2161	toxin-antitoxin pair type II binding
THMIRHAT_22420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
THMIRHAT_22430	COG1051	belongs to the nudix hydrolase family
THMIRHAT_22440	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
THMIRHAT_22440	COG0662	Cupin 2, conserved barrel domain protein
THMIRHAT_22460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
THMIRHAT_22530	COG0784	Response regulator, receiver
THMIRHAT_22530	COG2205	protein histidine kinase activity
THMIRHAT_22530	COG5002	protein histidine kinase activity
THMIRHAT_22540	COG2801	Transposase and inactivated derivatives
THMIRHAT_22850	COG0582	viral genome integration into host DNA
THMIRHAT_23050	COG0582	viral genome integration into host DNA
THMIRHAT_23070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
THMIRHAT_23120	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
THMIRHAT_23150	COG5001	Diguanylate cyclase
THMIRHAT_23150	COG4251	negative regulation of phosphorylation
THMIRHAT_23150	COG3706	GGDEF domain
THMIRHAT_23150	COG2203	Gaf domain
THMIRHAT_23230	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
THMIRHAT_23230	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
THMIRHAT_23270	COG3220	belongs to the UPF0276 family
THMIRHAT_23280	COG2337	Toxic component of a toxin-antitoxin (TA) module
THMIRHAT_23320	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
THMIRHAT_23330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
THMIRHAT_23400	COG1487	ribonuclease activity
THMIRHAT_23470	COG0840	transmembrane signaling receptor activity
THMIRHAT_23500	COG1739	Uncharacterized protein family UPF0029
THMIRHAT_23520	COG0840	transmembrane signaling receptor activity
THMIRHAT_23520	COG0840	transmembrane signaling receptor activity
THMIRHAT_23530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
THMIRHAT_23540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
THMIRHAT_23550	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
THMIRHAT_23560	COG2199	diguanylate cyclase activity
THMIRHAT_23560	COG2203	Gaf domain
THMIRHAT_23580	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
THMIRHAT_23600	COG0706	membrane insertase activity
THMIRHAT_23610	COG0594	ribonuclease P activity
THMIRHAT_23620	COG0230	Belongs to the bacterial ribosomal protein bL34 family
THMIRHAT_23730	COG0730	response to heat