locus-tag	class	description
THMIRHAS_00010	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
THMIRHAS_00020	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
THMIRHAS_00030	ENOG41076HS	cation diffusion facilitator family transporter
THMIRHAS_00040	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
THMIRHAS_00060	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
THMIRHAS_00170	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
THMIRHAS_00190	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
THMIRHAS_00210	ENOG4105EMN	RNA polymerase sigma factor
THMIRHAS_00300	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
THMIRHAS_00310	ENOG4105J0Q	Transcriptional regulator
THMIRHAS_00320	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
THMIRHAS_00330	ENOG410903C	(LipO)protein
THMIRHAS_00340	ENOG4105C5Q	Transcriptional regulator
THMIRHAS_00350	ENOG4107Y03	Nitroreductase
THMIRHAS_00370	ENOG4105C7K	acetolactate synthase
THMIRHAS_00390	ENOG4105CRE	cytochrome C
THMIRHAS_00400	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
THMIRHAS_00410	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
THMIRHAS_00430	ENOG4105C2M	dna polymerase I
THMIRHAS_00440	ENOG4105CUV	Homoserine Kinase
THMIRHAS_00450	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
THMIRHAS_00480	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
THMIRHAS_00490	ENOG4108IJ6	ABC transporter
THMIRHAS_00500	ENOG4107QKW	extracellular solute-binding protein family 1
THMIRHAS_00510	ENOG4107RCV	ABC transporter, permease
THMIRHAS_00520	ENOG4105VEJ	Heat shock protein
THMIRHAS_00530	ENOG4105KJM	monovalent cation h antiporter subunit g
THMIRHAS_00540	ENOG4105W4C	monovalent cation H antiporter subunit F
THMIRHAS_00560	ENOG4107R4Z	monovalent cation h antiporter subunit d
THMIRHAS_00570	ENOG4108ZE9	Monovalent cation H antiporter subunit C
THMIRHAS_00580	ENOG4105D65	subunit l
THMIRHAS_00590	ENOG4105BZU	Histidine kinase
THMIRHAS_00600	ENOG4105BZU	Histidine kinase
THMIRHAS_00720	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
THMIRHAS_00770	ENOG4105DGW	oligopeptidase A
THMIRHAS_00780	ENOG4107G9V	glycosyl transferase, family 39
THMIRHAS_00820	ENOG4105BZU	Histidine kinase
THMIRHAS_00850	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
THMIRHAS_00880	ENOG4105DS1	cytochrome b561
THMIRHAS_00890	ENOG4105EXG	Transcriptional regulator
THMIRHAS_00910	ENOG4105CEY	Amp-dependent synthetase and ligase
THMIRHAS_00920	ENOG4105CD5	CoA-binding domain protein
THMIRHAS_01000	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
THMIRHAS_01030	ENOG4106371	Methyltransferase
THMIRHAS_01050	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
THMIRHAS_01060	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
THMIRHAS_01080	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
THMIRHAS_01140	ENOG4105K63	Thioredoxin
THMIRHAS_01200	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
THMIRHAS_01210	ENOG4105CH7	arginosuccinase
THMIRHAS_01230	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
THMIRHAS_01280	ENOG4105HDD	phospholipase
THMIRHAS_01300	ENOG4105CGK	Exodeoxyribonuclease III
THMIRHAS_01320	ENOG4105CIY	formyltetrahydrofolate deformylase
THMIRHAS_01340	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
THMIRHAS_01350	ENOG4105E0X	reductase
THMIRHAS_01360	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
THMIRHAS_01380	ENOG4105DWF	phosphomethylpyrimidine kinase
THMIRHAS_01400	ENOG4105CBX	hi0933 family
THMIRHAS_01460	ENOG4108Z0R	Transferase
THMIRHAS_01490	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
THMIRHAS_01500	ENOG4105E2X	shikimate dehydrogenase
THMIRHAS_01520	ENOG4105D52	delta-aminolevulinic acid dehydratase
THMIRHAS_01560	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
THMIRHAS_01570	ENOG4105M00	molybdopterin converting factor, subunit 1
THMIRHAS_01580	ENOG4108ZAF	Molybdopterin
THMIRHAS_01590	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
THMIRHAS_01610	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
THMIRHAS_01620	ENOG4105BZU	Histidine kinase
THMIRHAS_01650	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
THMIRHAS_01690	ENOG4105C25	Primosomal protein n'
THMIRHAS_01700	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
THMIRHAS_01710	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
THMIRHAS_01730	ENOG4105BZG	amino acid carrier protein
THMIRHAS_01780	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
THMIRHAS_01790	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
THMIRHAS_01800	ENOG4105MJ2	Competence protein
THMIRHAS_01810	ENOG4105PGM	cation diffusion facilitator family transporter
THMIRHAS_01830	ENOG4105C7Z	Conserved Protein
THMIRHAS_01850	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
THMIRHAS_01860	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
THMIRHAS_01880	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
THMIRHAS_01890	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
THMIRHAS_01900	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
THMIRHAS_01910	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
THMIRHAS_01920	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
THMIRHAS_01930	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
THMIRHAS_01960	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
THMIRHAS_01980	ENOG4105C58	cytochrome c oxidase accessory protein ccog
THMIRHAS_02000	ENOG4105C59	p-type ATPase
THMIRHAS_02050	ENOG4105BZU	Histidine kinase
THMIRHAS_02060	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
THMIRHAS_02080	ENOG4105CI3	gtp-binding protein typa
THMIRHAS_02100	ENOG4105CUC	YeeE YedE family protein
THMIRHAS_02130	ENOG41083KI	ribonuclease, T2
THMIRHAS_02160	ENOG4105BZU	Histidine kinase
THMIRHAS_02210	ENOG4108VWS	Yaeq family
THMIRHAS_02220	ENOG4105C1J	atp-dependent rna helicase
THMIRHAS_02230	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
THMIRHAS_02240	ENOG4108MGY	Histidine kinase
THMIRHAS_02250	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
THMIRHAS_02250	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
THMIRHAS_02260	ENOG4107TPY	serine threonine protein kinase
THMIRHAS_02270	ENOG41060A7	DNA polymerase beta domain protein region
THMIRHAS_02280	ENOG4105C3R	Methionine synthase
THMIRHAS_02330	ENOG4105BZU	Histidine kinase
THMIRHAS_02340	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
THMIRHAS_02350	ENOG4108VCT	Sulfite exporter TauE/SafE
THMIRHAS_02390	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
THMIRHAS_02410	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
THMIRHAS_02440	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
THMIRHAS_02450	ENOG4105C1A	potassium transporter peripheral membrane
THMIRHAS_02460	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THMIRHAS_02470	ENOG4105ES5	Histidine kinase
THMIRHAS_02490	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
THMIRHAS_02500	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
THMIRHAS_02510	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
THMIRHAS_02520	ENOG4105C79	DNA protecting protein DprA
THMIRHAS_02540	ENOG4105C75	arginyL-tRNA synthetase
THMIRHAS_02570	ENOG4105W0Z	cytoplasmic protein
THMIRHAS_02580	ENOG4105C0P	Mg chelatase subunit ChlI
THMIRHAS_02610	ENOG4105WH1	Two component transcriptional regulator luxr family
THMIRHAS_02640	ENOG4105CDV	Ompa motb domain protein
THMIRHAS_02650	ENOG4105C0A	alcohol dehydrogenase
THMIRHAS_02660	ENOG4105C4R	Atp-dependent dna helicase
THMIRHAS_02670	ENOG4107Y49	methyltransferase
THMIRHAS_02700	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
THMIRHAS_02710	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
THMIRHAS_02730	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
THMIRHAS_02740	ENOG4105C3Q	Glycosyl transferase, family 2
THMIRHAS_02760	ENOG4105BZW	Glycerate kinase
THMIRHAS_02800	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
THMIRHAS_02810	ENOG4105VNG	YcgL domain-containing protein
THMIRHAS_02830	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
THMIRHAS_02880	ENOG4105BZS	acriflavin resistance protein
THMIRHAS_02890	ENOG4105CV1	Transketolase (EC 2.2.1.1)
THMIRHAS_02900	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
THMIRHAS_02910	ENOG4105BZA	Phosphoglycerate kinase
THMIRHAS_02920	ENOG4105CA9	Pyruvate kinase
THMIRHAS_02930	ENOG4105D2N	Aldolase
THMIRHAS_02940	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
THMIRHAS_03000	ENOG4105KNY	Microcompartments protein
THMIRHAS_03010	ENOG4105KNY	Microcompartments protein
THMIRHAS_03020	ENOG4105KNY	Microcompartments protein
THMIRHAS_03140	ENOG4105C8V	SAICAR synthetase
THMIRHAS_03160	ENOG4105DJV	ribulose-phosphate 3-epimerase
THMIRHAS_03170	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
THMIRHAS_03180	ENOG4105CRQ	synthase (Component I)
THMIRHAS_03190	ENOG4105DDQ	anthranilate synthase
THMIRHAS_03200	ENOG4107QYG	anthranilate phosphoribosyltransferase
THMIRHAS_03210	ENOG4105WD1	Membrane
THMIRHAS_03220	ENOG4105EUP	HipA domain protein
THMIRHAS_03270	ENOG4105DK0	Indole-3-glycerol phosphate synthase
THMIRHAS_03290	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
THMIRHAS_03300	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
THMIRHAS_03320	ENOG4108UKZ	OsmC family
THMIRHAS_03340	ENOG4105C1J	atp-dependent rna helicase
THMIRHAS_03350	ENOG4105EWT	decarboxylase family
THMIRHAS_03360	ENOG4105IPI	Membrane
THMIRHAS_03420	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
THMIRHAS_03430	ENOG4105CKI	cobalamin synthesis protein
THMIRHAS_03440	ENOG4107RSR	Malate quinone oxidoreductase
THMIRHAS_03460	ENOG410642E	Short chain dehydrogenase
THMIRHAS_03480	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
THMIRHAS_03490	ENOG4105DR5	peptidase
THMIRHAS_03500	ENOG4105VFE	sira family
THMIRHAS_03510	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
THMIRHAS_03520	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
THMIRHAS_03530	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
THMIRHAS_03550	ENOG4105E14	MotA TolQ exbB proton channel
THMIRHAS_03590	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
THMIRHAS_03600	ENOG4105BZU	Histidine kinase
THMIRHAS_03620	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
THMIRHAS_03620	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
THMIRHAS_03640	ENOG4105CNG	UPF0061 protein
THMIRHAS_03660	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
THMIRHAS_03670	ENOG4107RD7	Flagellar Motor Protein, MotA
THMIRHAS_03680	ENOG4106VK6	Flagellar motor protein
THMIRHAS_03690	ENOG4105D06	uba thif-type nad fad binding protein
THMIRHAS_03700	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
THMIRHAS_03710	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
THMIRHAS_03720	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
THMIRHAS_03750	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
THMIRHAS_03760	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
THMIRHAS_03770	ENOG4105C3G	gtp-binding protein
THMIRHAS_04030	ENOG4105BZU	Histidine kinase
THMIRHAS_04040	ENOG4108IY8	ABC, transporter
THMIRHAS_04060	ENOG4105DG7	nitrate ABC transporter
THMIRHAS_04100	ENOG4107QZF	nitrite reductase NADPH large subunit
THMIRHAS_04130	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
THMIRHAS_04150	ENOG4105C8Q	Methyl-accepting chemotaxis
THMIRHAS_04160	ENOG4105BZU	Histidine kinase
THMIRHAS_04200	ENOG4105GVR	general secretion pathway protein D
THMIRHAS_04210	ENOG4107QHF	type ii secretion system protein e
THMIRHAS_04220	ENOG4105D7Q	type ii secretion system
THMIRHAS_04230	ENOG4108VAU	general secretion pathway protein G
THMIRHAS_04240	ENOG4105VWV	general secretion pathway protein h
THMIRHAS_04260	ENOG4108WWZ	General secretion pathway protein J
THMIRHAS_04270	ENOG4108RTD	type II secretion system protein K
THMIRHAS_04280	ENOG4108ADH	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins (By similarity)
THMIRHAS_04350	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
THMIRHAS_04370	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
THMIRHAS_04390	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
THMIRHAS_04400	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
THMIRHAS_04430	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
THMIRHAS_04460	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
THMIRHAS_04470	ENOG4105C2X	Arabinose 5-phosphate isomerase
THMIRHAS_04490	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
THMIRHAS_04510	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
THMIRHAS_04520	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
THMIRHAS_04530	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
THMIRHAS_04550	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
THMIRHAS_04570	ENOG41090SZ	ABC-2 type transporter
THMIRHAS_04580	ENOG4105EY8	ABC transporter
THMIRHAS_04620	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
THMIRHAS_04630	ENOG4107TXM	Nad-dependent epimerase dehydratase
THMIRHAS_04650	ENOG4105F8J	Adenylate Guanylate cyclase
THMIRHAS_04670	ENOG4108W63	CRP FNR family transcriptional regulator
THMIRHAS_04780	ENOG4108YGG	dna repair protein
THMIRHAS_04800	ENOG4108KU3	Integrase
THMIRHAS_04820	ENOG4105VUH	addiction module killer protein
THMIRHAS_04960	ENOG4108KU3	Integrase
THMIRHAS_05080	ENOG4105DFG	type I secretion outer membrane protein
THMIRHAS_05090	ENOG4108JJ6	Type I secretion system ATPase
THMIRHAS_05130	ENOG41080HT	Transcriptional regulator, arsr family
THMIRHAS_05140	ENOG4105CN1	protease
THMIRHAS_05150	ENOG4107S0N	DJ-1 family
THMIRHAS_05170	ENOG4107S2Z	UPF0761 membrane protein
THMIRHAS_05180	ENOG4105EHG	Permease protein
THMIRHAS_05190	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
THMIRHAS_05230	ENOG4105K4U	addiction module toxin, RelE StbE family
THMIRHAS_05300	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
THMIRHAS_05310	ENOG4105CHH	sulfate transporter
THMIRHAS_05320	ENOG4105CZK	Aspartate kinase
THMIRHAS_05330	ENOG4105CAH	Chromate
THMIRHAS_05340	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
THMIRHAS_05350	ENOG4108JPW	Aminotransferase
THMIRHAS_05360	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
THMIRHAS_05380	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
THMIRHAS_05410	ENOG4105C5H	ABC transporter
THMIRHAS_05420	ENOG4105BZU	Histidine kinase
THMIRHAS_05430	ENOG4105ETX	regulatoR
THMIRHAS_05440	ENOG4105GR3	Histidine kinase
THMIRHAS_05460	ENOG4107QX9	Thiol disulfide interChange protein
THMIRHAS_05470	ENOG4105FQ6	thiopurine methyltransferase
THMIRHAS_05480	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
THMIRHAS_05500	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
THMIRHAS_05520	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
THMIRHAS_05530	ENOG4108YZ9	Urea amidohydrolase subunit gamma
THMIRHAS_05540	ENOG4105KI2	Urea amidohydrolase subunit beta
THMIRHAS_05550	ENOG4105CQM	Urea amidohydrolase subunit alpha
THMIRHAS_05560	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
THMIRHAS_05570	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
THMIRHAS_05580	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
THMIRHAS_05610	ENOG4108IV0	ABC, transporter
THMIRHAS_05620	ENOG4105C0Z	ABC transporter
THMIRHAS_05640	ENOG4105C32	Amino acid ABC transporter (Permease)
THMIRHAS_05660	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
THMIRHAS_05670	ENOG4105CKI	cobalamin synthesis protein
THMIRHAS_05690	ENOG4105F4R	Transcriptional regulator mode
THMIRHAS_05780	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
THMIRHAS_05810	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
THMIRHAS_05840	ENOG4105KXI	murein peptide amidase A
THMIRHAS_05850	ENOG4105CZX	twitching motility protein
THMIRHAS_05860	ENOG4105CZX	twitching motility protein
THMIRHAS_05880	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
THMIRHAS_05890	ENOG4108M8S	permease YjgP YjgQ family protein
THMIRHAS_05900	ENOG4108K5H	permease YjgP YjgQ family protein
THMIRHAS_05910	ENOG4105D6S	protein involved in catabolism of external DNA
THMIRHAS_05920	ENOG4107QKV	phosphomannomutase
THMIRHAS_05930	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
THMIRHAS_05950	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
THMIRHAS_05960	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THMIRHAS_05970	ENOG4105KT5	UmuD protein
THMIRHAS_06040	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
THMIRHAS_06060	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
THMIRHAS_06090	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
THMIRHAS_06100	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
THMIRHAS_06110	ENOG4105VIE	preprotein translocase, subunit YajC
THMIRHAS_06120	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
THMIRHAS_06130	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
THMIRHAS_06240	ENOG4108C33	Resolvase
THMIRHAS_06320	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
THMIRHAS_06340	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
THMIRHAS_06380	ENOG4105DFS	Conserved Protein
THMIRHAS_06400	ENOG4105PSV	Polysaccharide Biosynthesis Protein
THMIRHAS_06420	ENOG4105K64	Glycosyl transferase, family 2
THMIRHAS_06440	ENOG4105CG5	Glycosyl transferase (Group 1
THMIRHAS_06460	ENOG4105CPK	Glycosyl transferase (Group 1
THMIRHAS_06480	ENOG4105EXC	Acyl-transferase
THMIRHAS_06500	ENOG4105D3Q	Sugar transferase
THMIRHAS_06530	ENOG4105CMR	udp-glucose 4-epimerase
THMIRHAS_06560	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
THMIRHAS_06580	ENOG4105D3Q	Sugar transferase
THMIRHAS_06640	ENOG4105CDV	Ompa motb domain protein
THMIRHAS_06650	ENOG4105CJW	magnesium transporter
THMIRHAS_06660	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
THMIRHAS_06670	ENOG4108IUZ	ABC transporter
THMIRHAS_06700	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
THMIRHAS_06730	ENOG4105DHJ	ABC, transporter
THMIRHAS_06740	ENOG4105CY3	ABC transporter, permease
THMIRHAS_06750	ENOG4107PE3	Mammalian cell entry related domain protein
THMIRHAS_06780	ENOG4105DA5	(ABC) transporter
THMIRHAS_06790	ENOG4105E3A	(ABC) transporter
THMIRHAS_06810	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
THMIRHAS_06820	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
THMIRHAS_06830	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
THMIRHAS_06840	ENOG4107QNR	UPF0135 protein
THMIRHAS_06850	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
THMIRHAS_06860	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
THMIRHAS_06870	ENOG4105EIX	cytochrome c1
THMIRHAS_06880	ENOG4105CBC	glutamate synthase
THMIRHAS_06890	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
THMIRHAS_06900	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
THMIRHAS_06920	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
THMIRHAS_06930	ENOG4105ECY	inositol monophosphatase
THMIRHAS_06940	ENOG4108JU6	CBS domain protein
THMIRHAS_06960	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
THMIRHAS_06970	ENOG4105K5M	30s ribosomal protein S16
THMIRHAS_06980	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
THMIRHAS_06990	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
THMIRHAS_07000	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
THMIRHAS_07010	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
THMIRHAS_07040	ENOG4105T95	Thiol disulfide interChange protein
THMIRHAS_07100	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
THMIRHAS_07110	ENOG4105I03	Flagellin
THMIRHAS_07150	ENOG4108YZA	Nitrogen regulatory protein pii
THMIRHAS_07170	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
THMIRHAS_07180	ENOG4105C5F	glutamine synthetase
THMIRHAS_07200	ENOG4105C8U	phosphate abc transporter
THMIRHAS_07210	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
THMIRHAS_07220	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
THMIRHAS_07230	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
THMIRHAS_07240	ENOG4105BZU	Histidine kinase
THMIRHAS_07250	ENOG4108UYB	regulatoR
THMIRHAS_07300	ENOG4105CJ3	phosphate transporter
THMIRHAS_07310	ENOG4105DJH	phosphate
THMIRHAS_07350	ENOG4105M85	Bola protein
THMIRHAS_07370	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
THMIRHAS_07380	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
THMIRHAS_07390	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
THMIRHAS_07400	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
THMIRHAS_07410	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
THMIRHAS_07420	ENOG4105EHM	Aminoglycoside phosphotransferase
THMIRHAS_07430	ENOG4108S0S	Nucleotidyl transferase
THMIRHAS_07440	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
THMIRHAS_07450	ENOG4107QMS	site-determining protein
THMIRHAS_07460	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
THMIRHAS_07470	ENOG4105D1Q	UPF0246 protein
THMIRHAS_07480	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
THMIRHAS_07550	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
THMIRHAS_07580	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
THMIRHAS_07590	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
THMIRHAS_07600	ENOG4108Z43	UPF0250 protein
THMIRHAS_07610	ENOG4105DZ1	carboxypeptidase
THMIRHAS_07620	ENOG4105CNI	cell division protein FtsW
THMIRHAS_07630	ENOG4105CJN	penicillin-binding protein
THMIRHAS_07650	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
THMIRHAS_07670	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
THMIRHAS_07680	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
THMIRHAS_07690	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
THMIRHAS_07720	ENOG4105D0M	Protease HtpX homolog
THMIRHAS_07730	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
THMIRHAS_07740	ENOG41067XB	TonB family
THMIRHAS_07750	ENOG4105M15	transport protein ExbD
THMIRHAS_07760	ENOG4105M8K	biopolymer transport protein
THMIRHAS_07790	ENOG4105GAV	receptor
THMIRHAS_07800	ENOG4105EAC	phosphoserine phosphatase
THMIRHAS_07840	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
THMIRHAS_07850	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
THMIRHAS_07860	ENOG4108Z6B	deaminase
THMIRHAS_07870	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
THMIRHAS_07880	ENOG4105CBS	Chea signal transduction histidine kinase
THMIRHAS_07910	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
THMIRHAS_07920	ENOG4105BZU	Histidine kinase
THMIRHAS_07940	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
THMIRHAS_07980	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
THMIRHAS_08020	ENOG4105E7D	Protein of unknown function (DUF3375)
THMIRHAS_08120	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
THMIRHAS_08130	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
THMIRHAS_08150	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
THMIRHAS_08160	ENOG4107TH8	cina domain protein
THMIRHAS_08170	ENOG4105CQZ	Histidine kinase
THMIRHAS_08180	ENOG4105BZU	Histidine kinase
THMIRHAS_08270	ENOG4105E5H	Transposase
THMIRHAS_08370	ENOG4105BZU	Histidine kinase
THMIRHAS_08390	ENOG4105F5W	AtP-binding protein
THMIRHAS_08420	ENOG410600T	transposase
THMIRHAS_08430	ENOG4105BZU	Histidine kinase
THMIRHAS_08450	ENOG4105C8Q	Methyl-accepting chemotaxis
THMIRHAS_08460	ENOG4105C31	Tryptophanyl-tRNA synthetase
THMIRHAS_08480	ENOG4105DJ0	Poly(A) Polymerase
THMIRHAS_08490	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
THMIRHAS_08500	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
THMIRHAS_08510	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
THMIRHAS_08520	ENOG4105E14	MotA TolQ exbB proton channel
THMIRHAS_08530	ENOG4106VK6	Flagellar motor protein
THMIRHAS_08540	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
THMIRHAS_08550	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
THMIRHAS_08570	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
THMIRHAS_08580	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
THMIRHAS_08590	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
THMIRHAS_08600	ENOG4107QN2	dihydrolipoyl dehydrogenase
THMIRHAS_08610	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
THMIRHAS_08620	ENOG4105C2N	RNA methyltransferase TrmH family group 3
THMIRHAS_08630	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
THMIRHAS_08640	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
THMIRHAS_08650	ENOG4105KCK	Peptidoglycan-associated lipoprotein
THMIRHAS_08660	ENOG4105CD8	aminopeptidase N
THMIRHAS_08780	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
THMIRHAS_08790	ENOG4108ZC9	flagellar basal-body rod protein flgc
THMIRHAS_08800	ENOG410822I	Flagellar hook capping protein
THMIRHAS_08810	ENOG4105BZE	flagellar hook protein, FlgE
THMIRHAS_08820	ENOG4105CGA	flagellar basal-body rod protein FlgG
THMIRHAS_08830	ENOG4105CGA	flagellar basal-body rod protein FlgG
THMIRHAS_08840	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
THMIRHAS_08850	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
THMIRHAS_08860	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
THMIRHAS_08880	ENOG4105DTJ	flagellar hook-associated protein
THMIRHAS_08890	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
THMIRHAS_08900	ENOG4108IAJ	Nad-dependent epimerase dehydratase
THMIRHAS_08910	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
THMIRHAS_08930	ENOG4105D2T	synthase
THMIRHAS_08940	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
THMIRHAS_08980	ENOG4105F0R	Cytidylyltransferase
THMIRHAS_09000	ENOG4105I03	Flagellin
THMIRHAS_09010	ENOG4105I03	Flagellin
THMIRHAS_09050	ENOG4105MQ3	flagellar protein FliS
THMIRHAS_09080	ENOG4105BZU	Histidine kinase
THMIRHAS_09100	ENOG4105X6K	flagellar hook-basal body complex protein fliE
THMIRHAS_09110	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
THMIRHAS_09120	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
THMIRHAS_09140	ENOG4108JIR	Flagellum-specific ATP synthase
THMIRHAS_09170	ENOG4108NVR	Methyl-accepting chemotaxis
THMIRHAS_09180	ENOG4107RD7	Flagellar Motor Protein, MotA
THMIRHAS_09190	ENOG4105ER2	Ompa motb domain protein
THMIRHAS_09210	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
THMIRHAS_09220	ENOG4105DD5	Flagellar motor switch protein
THMIRHAS_09230	ENOG4105VTB	flagellar biosynthesis protein fliO
THMIRHAS_09240	ENOG4105CN7	Flagellar biosynthetic protein FliP
THMIRHAS_09250	ENOG4105VS8	Flagellar biosynthetic protein fliq
THMIRHAS_09260	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
THMIRHAS_09270	ENOG4105D00	flagellar biosynthetic protein flhB
THMIRHAS_09280	ENOG4105D7B	Flagellar biosynthesis protein flha
THMIRHAS_09290	ENOG4105FZW	flagellar biosynthesis regulator FlhF
THMIRHAS_09310	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THMIRHAS_09320	ENOG4108VYJ	response regulator receiver protein
THMIRHAS_09330	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
THMIRHAS_09350	ENOG4105YFD	chemotaxis, protein
THMIRHAS_09360	ENOG4105VM1	flagellar
THMIRHAS_09380	ENOG4108VYJ	response regulator receiver protein
THMIRHAS_09390	ENOG4108V3W	Chemotaxis protein, CheW
THMIRHAS_09410	ENOG4105BZU	Histidine kinase
THMIRHAS_09420	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
THMIRHAS_09430	ENOG4105C8Q	Methyl-accepting chemotaxis
THMIRHAS_09450	ENOG4105EGD	dinuclear metal center protein, YbgI family
THMIRHAS_09460	ENOG4108V1T	peptidylprolyl cis-trans isomerase
THMIRHAS_09470	ENOG4105C3M	thioredoxin reductase
THMIRHAS_09480	ENOG4105CNU	cell division protein FtsK
THMIRHAS_09500	ENOG4105D1H	recombination factor protein RarA
THMIRHAS_09510	ENOG4105WMR	Protein CrcB homolog
THMIRHAS_09520	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
THMIRHAS_09540	ENOG4105DFP	Integrase
THMIRHAS_09570	ENOG4105EB3	Histidine kinase
THMIRHAS_09580	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
THMIRHAS_09610	ENOG4107SDU	Methyl-accepting chemotaxis
THMIRHAS_09620	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THMIRHAS_09640	ENOG4105BZU	Histidine kinase
THMIRHAS_09660	ENOG4105CM6	amino acid regulated cytosolic protein
THMIRHAS_09680	ENOG4105D05	Receptor
THMIRHAS_09720	ENOG4105EHG	Permease protein
THMIRHAS_09730	ENOG4105E0A	ABC, transporter
THMIRHAS_09740	ENOG4107USA	Thioredoxin
THMIRHAS_09790	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
THMIRHAS_09810	ENOG4105BZU	Histidine kinase
THMIRHAS_09820	ENOG4105WH1	Two component transcriptional regulator luxr family
THMIRHAS_09840	ENOG4108JJA	ABC, transporter
THMIRHAS_09850	ENOG4105CDV	Ompa motb domain protein
THMIRHAS_10000	ENOG4105E5H	Transposase
THMIRHAS_10120	ENOG4105E5H	Transposase
THMIRHAS_10190	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
THMIRHAS_10200	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
THMIRHAS_10210	ENOG4105DFU	Cell wall formation (By similarity)
THMIRHAS_10270	ENOG4108BPE	-transporting atpase
THMIRHAS_10300	ENOG4105CQ7	ATP-dependent helicase
THMIRHAS_10320	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
THMIRHAS_10330	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
THMIRHAS_10340	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THMIRHAS_10350	ENOG4105E66	phosphoriboisomerase A
THMIRHAS_10390	ENOG4105C7B	Threonine dehydratase
THMIRHAS_10410	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
THMIRHAS_10420	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
THMIRHAS_10430	ENOG4105K8N	protein family UPF0079, ATPase
THMIRHAS_10440	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
THMIRHAS_10450	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
THMIRHAS_10480	ENOG4107RAQ	aminopeptidase
THMIRHAS_10500	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
THMIRHAS_10530	ENOG4108IAB	Phoh family
THMIRHAS_10550	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THMIRHAS_10560	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
THMIRHAS_10580	ENOG4108ETH	Formylglycinamide ribotide synthetase
THMIRHAS_10610	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
THMIRHAS_10630	ENOG4105D38	putrescine abc transporter
THMIRHAS_10640	ENOG4105F38	ABC transporter, permease
THMIRHAS_10650	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
THMIRHAS_10660	ENOG4107RUE	extracellular solute-binding protein family 1
THMIRHAS_10670	ENOG4105BZ8	glutamate synthase
THMIRHAS_10700	ENOG4105C5H	ABC transporter
THMIRHAS_10710	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
THMIRHAS_10720	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
THMIRHAS_10730	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
THMIRHAS_10760	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
THMIRHAS_10770	ENOG4107YIM	Involved in the transcription termination process (By similarity)
THMIRHAS_10780	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
THMIRHAS_10790	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
THMIRHAS_10830	ENOG4107XVI	synthase
THMIRHAS_10840	ENOG4105CTB	Polyprenyl synthetase
THMIRHAS_10870	ENOG4105C9M	aspartyl-trna synthetase
THMIRHAS_10880	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
THMIRHAS_10890	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
THMIRHAS_10900	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
THMIRHAS_10910	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
THMIRHAS_10920	ENOG4105E02	MotA TolQ exbB proton channel
THMIRHAS_10930	ENOG4105M8F	Biopolymer transport protein exbD tolR
THMIRHAS_10950	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
THMIRHAS_10960	ENOG4105KCK	Peptidoglycan-associated lipoprotein
THMIRHAS_10980	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
THMIRHAS_11010	ENOG4105CUX	Signal transduction histidine kinase
THMIRHAS_11020	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THMIRHAS_11040	ENOG4105W39	Membrane
THMIRHAS_11050	ENOG4108YZA	Nitrogen regulatory protein pii
THMIRHAS_11060	ENOG4105DJ4	phosphatidylserine decarboxylase
THMIRHAS_11070	ENOG4105CDH	Citrulline--aspartate ligase
THMIRHAS_11080	ENOG4105VEQ	Cold shock protein
THMIRHAS_11100	ENOG4108ZAI	phosphatidylglycerophosphatase a
THMIRHAS_11120	ENOG4105CK2	sodium dicarboxylate symporter
THMIRHAS_11130	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
THMIRHAS_11160	ENOG4105C8N	cysteinyl-tRNA synthetase
THMIRHAS_11170	ENOG4107SC1	transglycosylase
THMIRHAS_11180	ENOG4105E9H	Lytic Murein transglycosylase
THMIRHAS_11190	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
THMIRHAS_11200	ENOG4105D1A	Methyltransferase
THMIRHAS_11210	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
THMIRHAS_11220	ENOG4107RZZ	dna polymerase iii epsilon subunit
THMIRHAS_11230	ENOG4108YZY	peptidylprolyl cis-trans isomerase
THMIRHAS_11250	ENOG4105CQ7	ATP-dependent helicase
THMIRHAS_11260	ENOG4105Z6S	cytochrome C, class I
THMIRHAS_11320	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
THMIRHAS_11330	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
THMIRHAS_11340	ENOG4105C4K	Nad synthetase
THMIRHAS_11350	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
THMIRHAS_11360	ENOG4105C34	Pseudouridine synthase
THMIRHAS_11370	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
THMIRHAS_11390	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
THMIRHAS_11420	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
THMIRHAS_11440	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
THMIRHAS_11450	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
THMIRHAS_11460	ENOG4107QSN	dihydrolipoamide acetyltransferase
THMIRHAS_11470	ENOG4107QN2	dihydrolipoyl dehydrogenase
THMIRHAS_11510	ENOG4105VRT	cytoplasmic protein
THMIRHAS_11520	ENOG4105DCF	alanine dehydrogenase
THMIRHAS_11550	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
THMIRHAS_11560	ENOG4105D58	Diguanylate phosphodiesterase
THMIRHAS_11580	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
THMIRHAS_11600	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
THMIRHAS_11610	ENOG4105C1J	atp-dependent rna helicase
THMIRHAS_11630	ENOG4105IUQ	nucleoprotein polynucleotide-associated enzyme
THMIRHAS_11650	ENOG4105C1J	atp-dependent rna helicase
THMIRHAS_11660	ENOG4105C5H	ABC transporter
THMIRHAS_11670	ENOG4108UPT	UPF0178 protein
THMIRHAS_11680	ENOG4108RCM	Nitroreductase
THMIRHAS_11700	ENOG4107QJE	Chromosome Partitioning Protein
THMIRHAS_11730	ENOG4108V1T	peptidylprolyl cis-trans isomerase
THMIRHAS_11740	ENOG4105BZU	Histidine kinase
THMIRHAS_11800	ENOG4108W1A	pseudouridine synthase
THMIRHAS_11810	ENOG4108ZZ3	UPF0260 protein
THMIRHAS_11830	ENOG4108YZY	peptidylprolyl cis-trans isomerase
THMIRHAS_11840	ENOG4108YXA	Membrane
THMIRHAS_11890	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
THMIRHAS_11930	ENOG4105CFP	Peptidase U32
THMIRHAS_11940	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
THMIRHAS_11990	ENOG4105C8Q	Methyl-accepting chemotaxis
THMIRHAS_12010	ENOG4105C6T	cysteine synthase
THMIRHAS_12050	ENOG4105DEF	Extracellular solute-binding protein, family 5
THMIRHAS_12070	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
THMIRHAS_12080	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
THMIRHAS_12100	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
THMIRHAS_12110	ENOG4105D64	Mechanosensitive ion channel
THMIRHAS_12120	ENOG4105VV6	START domain-containing protein
THMIRHAS_12130	ENOG4107R0I	Cell wall formation (By similarity)
THMIRHAS_12140	ENOG4105C8J	)-transporter
THMIRHAS_12190	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
THMIRHAS_12220	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
THMIRHAS_12240	ENOG4105BZU	Histidine kinase
THMIRHAS_12270	ENOG4108JA2	transcriptioN-repair coupling factor
THMIRHAS_12290	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
THMIRHAS_12310	ENOG4105EN6	Membrane
THMIRHAS_12330	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
THMIRHAS_12340	ENOG4105C5H	ABC transporter
THMIRHAS_12360	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
THMIRHAS_12570	ENOG4107SDU	Methyl-accepting chemotaxis
THMIRHAS_12590	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
THMIRHAS_12600	ENOG4105KUZ	arsenate reductase
THMIRHAS_12610	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
THMIRHAS_12630	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
THMIRHAS_12640	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
THMIRHAS_12650	ENOG4105CE9	30S ribosomal protein S2
THMIRHAS_12660	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
THMIRHAS_12670	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
THMIRHAS_12680	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
THMIRHAS_12690	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
THMIRHAS_12700	ENOG4105KNE	Phosphatidate cytidylyltransferase
THMIRHAS_12710	ENOG4105DZP	Membrane-associated zinc metalloprotease
THMIRHAS_12720	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
THMIRHAS_12740	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
THMIRHAS_12750	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
THMIRHAS_12760	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
THMIRHAS_12770	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
THMIRHAS_12780	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
THMIRHAS_12790	ENOG4107R88	Chemotaxis protein (CheV)
THMIRHAS_12830	ENOG4105DVT	helicase
THMIRHAS_12840	ENOG41072GX	Peptidase M22 Glycoprotease
THMIRHAS_12880	ENOG4105DDY	UPF0142 protein ycaO
THMIRHAS_12900	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
THMIRHAS_12910	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
THMIRHAS_12920	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
THMIRHAS_12930	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
THMIRHAS_12940	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
THMIRHAS_12950	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
THMIRHAS_12970	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
THMIRHAS_12980	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
THMIRHAS_12990	ENOG4108UM1	dedA family
THMIRHAS_13000	ENOG4108K5P	(LipO)protein
THMIRHAS_13020	ENOG4105CHM	Aminotransferase
THMIRHAS_13030	ENOG4105D6E	homoserine dehydrogenase
THMIRHAS_13050	ENOG4107QID	Threonine synthase
THMIRHAS_13110	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
THMIRHAS_13120	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
THMIRHAS_13140	ENOG4107S5T	Carbohydrate kinase
THMIRHAS_13160	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
THMIRHAS_13170	ENOG4105N42	UPF0307 protein
THMIRHAS_13200	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
THMIRHAS_13210	ENOG4105K9H	YciI-like protein
THMIRHAS_13220	ENOG4107835	probably involved in intracellular septation (By similarity)
THMIRHAS_13230	ENOG4105DB7	PHP domain protein
THMIRHAS_13240	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
THMIRHAS_13250	ENOG4108Z4T	Peptidase M50
THMIRHAS_13260	ENOG4105FE9	pseudouridine synthase
THMIRHAS_13270	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THMIRHAS_13330	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
THMIRHAS_13340	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
THMIRHAS_13350	ENOG4105BZU	Histidine kinase
THMIRHAS_13370	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
THMIRHAS_13380	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
THMIRHAS_13470	ENOG4105K5B	UPF0225 protein
THMIRHAS_13480	ENOG4107QI1	Mate efflux family protein
THMIRHAS_13500	ENOG41087AY	ADP-Ribose pyrophosphatase
THMIRHAS_13510	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
THMIRHAS_13520	ENOG4105CDU	Replicative dna helicase
THMIRHAS_13530	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
THMIRHAS_13550	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
THMIRHAS_13560	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
THMIRHAS_13570	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
THMIRHAS_13590	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
THMIRHAS_13600	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
THMIRHAS_13610	ENOG4105CAT	Cytidine monophosphate kinase
THMIRHAS_13620	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
THMIRHAS_13630	ENOG4105EVN	Prephenate dehydrogenase
THMIRHAS_13640	ENOG4105CIH	Imidazole acetol-phosphate transaminase
THMIRHAS_13660	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
THMIRHAS_13670	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
THMIRHAS_13680	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
THMIRHAS_13690	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
THMIRHAS_13700	ENOG4105CHR	reductase
THMIRHAS_13710	ENOG4108JQ6	ABC transporter
THMIRHAS_13730	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
THMIRHAS_13740	ENOG4105DEF	Extracellular solute-binding protein, family 5
THMIRHAS_13750	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
THMIRHAS_13770	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
THMIRHAS_13780	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
THMIRHAS_13790	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
THMIRHAS_13800	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
THMIRHAS_13860	ENOG4107QIJ	Aconitate hydratase 2
THMIRHAS_13880	ENOG4107QTF	adenylosuccinate lyase
THMIRHAS_13900	ENOG4105CJ1	ABC, transporter
THMIRHAS_13910	ENOG4107QWP	ABC-2 type transporter
THMIRHAS_13920	ENOG4105EZE	Cupin 4 family protein
THMIRHAS_13930	ENOG4105K63	Thioredoxin
THMIRHAS_13950	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
THMIRHAS_13960	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
THMIRHAS_13980	ENOG41088CC	tellurite resistance protein tehB
THMIRHAS_13990	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
THMIRHAS_14000	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
THMIRHAS_14010	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
THMIRHAS_14020	ENOG4105CHV	Transcription elongation factor NusA
THMIRHAS_14030	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
THMIRHAS_14040	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
THMIRHAS_14080	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
THMIRHAS_14090	ENOG4105C0B	DNA polymerase III (alpha subunit)
THMIRHAS_14100	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
THMIRHAS_14110	ENOG4108UTY	succinate dehydrogenase, cytochrome b556 subunit
THMIRHAS_14130	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
THMIRHAS_14140	ENOG4105E33	succinate dehydrogenase
THMIRHAS_14160	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
THMIRHAS_14180	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
THMIRHAS_14190	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
THMIRHAS_14210	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
THMIRHAS_14220	ENOG4105CDY	transcriptional regulatory protein
THMIRHAS_14260	ENOG4108R99	pseudouridine synthase
THMIRHAS_14270	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
THMIRHAS_14280	ENOG41075W9	High frequency lysogenization protein HflD homolog
THMIRHAS_14300	ENOG4105EIN	peptidylprolyl cis-trans isomerase
THMIRHAS_14320	ENOG4108VYJ	response regulator receiver protein
THMIRHAS_14360	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
THMIRHAS_14370	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
THMIRHAS_14390	ENOG4105EPW	hflc protein
THMIRHAS_14400	ENOG4107QJR	hflk protein
THMIRHAS_14410	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
THMIRHAS_14420	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
THMIRHAS_14430	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
THMIRHAS_14450	ENOG4105D1F	ATP-binding protein
THMIRHAS_14460	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
THMIRHAS_14470	ENOG4105DGN	Electron transport complex
THMIRHAS_14480	ENOG4108R3D	Electron transport complex
THMIRHAS_14520	ENOG4105DZB	Electron transport complex
THMIRHAS_14540	ENOG4105CSM	endonuclease III
THMIRHAS_14590	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THMIRHAS_14610	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
THMIRHAS_14640	ENOG4105CX6	glutaminyL-tRNA synthetase
THMIRHAS_14660	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
THMIRHAS_14670	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
THMIRHAS_14700	ENOG4105EVH	UPF0753 protein
THMIRHAS_14720	ENOG4105EGS	Mechanosensitive ion channel
THMIRHAS_14730	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
THMIRHAS_14740	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
THMIRHAS_14750	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
THMIRHAS_14760	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
THMIRHAS_14770	ENOG4105VCH	membrane
THMIRHAS_14790	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
THMIRHAS_14800	ENOG4105W49	UPF0434 protein
THMIRHAS_14810	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
THMIRHAS_14820	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
THMIRHAS_14840	ENOG4105DAN	ATP-dependent protease
THMIRHAS_14900	ENOG4108YZT	Adenosylcobinamide kinase
THMIRHAS_14930	ENOG4108RRZ	Transcription elongation factor GreB
THMIRHAS_14950	ENOG4105C09	Bile acid
THMIRHAS_14960	ENOG4105BZU	Histidine kinase
THMIRHAS_14980	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
THMIRHAS_14990	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
THMIRHAS_15010	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
THMIRHAS_15020	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
THMIRHAS_15030	ENOG4105C3F	Signal peptidase i
THMIRHAS_15040	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
THMIRHAS_15050	ENOG4105C0H	protease
THMIRHAS_15070	ENOG4108IYU	L-aspartate oxidase
THMIRHAS_15080	ENOG4108V3W	Chemotaxis protein, CheW
THMIRHAS_15090	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
THMIRHAS_15240	ENOG4105E5H	Transposase
THMIRHAS_15330	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
THMIRHAS_15360	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
THMIRHAS_15370	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
THMIRHAS_15450	ENOG4105ECX	polysaccharide export
THMIRHAS_15470	ENOG41090SZ	ABC-2 type transporter
THMIRHAS_15480	ENOG4107V1M	polysaccharide export protein
THMIRHAS_15500	ENOG41084CK	capsule polysaccharide
THMIRHAS_15530	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
THMIRHAS_15550	ENOG4105CRK	lysyL-tRNA synthetase
THMIRHAS_15580	ENOG4105WH1	Two component transcriptional regulator luxr family
THMIRHAS_15600	ENOG41080RH	Thioredoxin
THMIRHAS_15610	ENOG4105E1F	short-chain dehydrogenase reductase
THMIRHAS_15620	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
THMIRHAS_15630	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
THMIRHAS_15640	ENOG4108I0Q	anthranilate phosphoribosyltransferase
THMIRHAS_15650	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
THMIRHAS_15670	ENOG4105WZK	nitrite reductase NADPH small subunit
THMIRHAS_15690	ENOG4107RNU	major facilitator superfamily MFS_1
THMIRHAS_15720	ENOG4108WQI	RNA Polymerase
THMIRHAS_15740	ENOG4105FE9	pseudouridine synthase
THMIRHAS_15760	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
THMIRHAS_15780	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
THMIRHAS_15800	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
THMIRHAS_15830	ENOG4105E8R	UPF0173 metal-dependent hydrolase
THMIRHAS_15870	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
THMIRHAS_15900	ENOG4107ZT5	Thiol disulfide interchange protein
THMIRHAS_15910	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
THMIRHAS_15930	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
THMIRHAS_15940	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
THMIRHAS_15960	ENOG4105DHP	deoxycytidine triphosphate deaminase
THMIRHAS_15980	ENOG4107QZF	nitrite reductase NADPH large subunit
THMIRHAS_15990	ENOG4108IFG	nitrite reductase, (NAD(P)H)
THMIRHAS_16000	ENOG4105D7T	ABC transporter
THMIRHAS_16050	ENOG4105DKQ	ROK family
THMIRHAS_16060	ENOG4105ED9	Protein of unknown function (DUF455)
THMIRHAS_16090	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
THMIRHAS_16100	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
THMIRHAS_16110	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
THMIRHAS_16120	ENOG4107TT5	NLP P60 protein
THMIRHAS_16130	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
THMIRHAS_16140	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
THMIRHAS_16150	ENOG4105CFG	Acts as a chaperone (By similarity)
THMIRHAS_16160	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
THMIRHAS_16170	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
THMIRHAS_16180	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
THMIRHAS_16190	ENOG41090R7	Ferric uptake
THMIRHAS_16220	ENOG4108Z1B	Cyclase dehydrase
THMIRHAS_16240	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
THMIRHAS_16250	ENOG4105BZU	Histidine kinase
THMIRHAS_16260	ENOG4105BZU	Histidine kinase
THMIRHAS_16300	ENOG4105F8V	Hydrolase, tatD family
THMIRHAS_16310	ENOG4107QRG	dna polymerase iii
THMIRHAS_16320	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
THMIRHAS_16330	ENOG4105HHA	aminodeoxychorismate lyase
THMIRHAS_16340	ENOG4105YAZ	4-amino-4-deoxychorismate lyase
THMIRHAS_16360	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
THMIRHAS_16370	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
THMIRHAS_16380	ENOG4105CHR	reductase
THMIRHAS_16390	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
THMIRHAS_16400	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
THMIRHAS_16410	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
THMIRHAS_16420	ENOG4105VGS	50s ribosomal protein l32
THMIRHAS_16440	ENOG4108UHJ	MAF-like protein
THMIRHAS_16450	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
THMIRHAS_16460	ENOG4105EI2	Pseudouridine synthase
THMIRHAS_16470	ENOG4105C03	ribonuclease
THMIRHAS_16480	ENOG4105KJF	protein tyrosine phosphatase
THMIRHAS_16490	ENOG4105D3G	Pseudouridine synthase
THMIRHAS_16520	ENOG4108KU3	Integrase
THMIRHAS_17060	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
THMIRHAS_17200	ENOG4107U53	septum site-determining protein minD
THMIRHAS_17210	ENOG4107SDU	Methyl-accepting chemotaxis
THMIRHAS_17240	ENOG41088T4	Helicase IV
THMIRHAS_17260	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THMIRHAS_17270	ENOG4105C8S	subunit m
THMIRHAS_17290	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THMIRHAS_17300	ENOG4105DF2	NADH dehydrogenase subunit j
THMIRHAS_17310	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THMIRHAS_17320	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
THMIRHAS_17330	ENOG4108IEH	NADH dehydrogenase subunit g
THMIRHAS_17340	ENOG4107QIZ	NADH dehydrogenase
THMIRHAS_17360	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THMIRHAS_17370	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
THMIRHAS_17380	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THMIRHAS_17390	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
THMIRHAS_17400	ENOG4107EJC	Preprotein translocase subunit SecG
THMIRHAS_17410	ENOG4105CP7	Triose-phosphate isomerase
THMIRHAS_17420	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
THMIRHAS_17430	ENOG4105EEI	dihydropteroate synthase
THMIRHAS_17440	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
THMIRHAS_17450	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
THMIRHAS_17460	ENOG4105HBR	Rna-binding protein
THMIRHAS_17470	ENOG4105C28	cystathionine
THMIRHAS_17480	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
THMIRHAS_17500	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
THMIRHAS_17510	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
THMIRHAS_17520	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
THMIRHAS_17540	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
THMIRHAS_17550	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
THMIRHAS_17560	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
THMIRHAS_17580	ENOG4105DR5	peptidase
THMIRHAS_17590	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
THMIRHAS_17600	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
THMIRHAS_17610	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
THMIRHAS_17630	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
THMIRHAS_17650	ENOG4105DZ2	Transcriptional regulator
THMIRHAS_17680	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
THMIRHAS_17700	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
THMIRHAS_17710	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
THMIRHAS_17750	ENOG4105DSE	periplasmic solute binding protein
THMIRHAS_17760	ENOG4105DIK	(ABC) transporter
THMIRHAS_17770	ENOG4105CC5	ABC transporter
THMIRHAS_17780	ENOG4105CC5	ABC transporter
THMIRHAS_17790	ENOG4107RPQ	ABC transporter
THMIRHAS_17810	ENOG4105CHH	sulfate transporter
THMIRHAS_17830	ENOG4105PWE	CRISPR-associated protein cas2
THMIRHAS_17840	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
THMIRHAS_17850	ENOG4108VWQ	crispr-associated protein
THMIRHAS_17860	ENOG41060M0	Crispr-associated protein, cse4 family
THMIRHAS_17930	ENOG4105NBK	UPF0345 protein
THMIRHAS_17960	ENOG4105MYN	Zinc uptake regulation protein
THMIRHAS_17970	ENOG4105D8G	Major Facilitator superfamily
THMIRHAS_17980	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
THMIRHAS_18000	ENOG4108UHE	carbonic anhydrase
THMIRHAS_18010	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
THMIRHAS_18020	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
THMIRHAS_18030	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
THMIRHAS_18050	ENOG4108UJV	acyl-CoA thioesterase i
THMIRHAS_18060	ENOG4108I0Y	(ABC) transporter
THMIRHAS_18070	ENOG4105CV6	ABC transporter, permease
THMIRHAS_18130	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
THMIRHAS_18140	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
THMIRHAS_18150	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
THMIRHAS_18160	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
THMIRHAS_18170	ENOG41082NX	50s ribosomal protein l35
THMIRHAS_18190	ENOG4105C22	threonyL-tRNA synthetase
THMIRHAS_18210	ENOG4107ZSV	Receptor
THMIRHAS_18250	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
THMIRHAS_18290	ENOG4107S7U	Sulfide dehydrogenase
THMIRHAS_18300	ENOG41090Y2	cytochrome C
THMIRHAS_18320	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
THMIRHAS_18330	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
THMIRHAS_18350	ENOG4108KMM	Diguanylate cyclase
THMIRHAS_18360	ENOG4105RK9	auxin efflux carrier
THMIRHAS_18440	ENOG4105EXC	Acyl-transferase
THMIRHAS_18450	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
THMIRHAS_18460	ENOG4108ZP8	Acetolactate synthase small subunit
THMIRHAS_18470	ENOG4105C7K	acetolactate synthase
THMIRHAS_18480	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
THMIRHAS_18490	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
THMIRHAS_18500	ENOG41090A4	Pterin carbinolamine dehydratase
THMIRHAS_18530	ENOG4105Z6S	cytochrome C, class I
THMIRHAS_18540	ENOG4106RE7	Cytochrome
THMIRHAS_18560	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
THMIRHAS_18570	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
THMIRHAS_18590	ENOG4105CUT	histidyl-tRNA synthetase
THMIRHAS_18610	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
THMIRHAS_18620	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
THMIRHAS_18630	ENOG4108Z4V	iron-sulfur cluster assembly
THMIRHAS_18640	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
THMIRHAS_18670	ENOG4105ECY	inositol monophosphatase
THMIRHAS_18680	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
THMIRHAS_18700	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
THMIRHAS_18710	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
THMIRHAS_18720	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
THMIRHAS_18740	ENOG4105ERG	peptidase m48, ste24p
THMIRHAS_18780	ENOG41088H4	Diheme cytochrome SoxA (Sulfur oxidation)
THMIRHAS_18800	ENOG4105C01	Dihydroxy-acid dehydratase
THMIRHAS_18810	ENOG4107QZM	n-acetylglutamate synthase
THMIRHAS_18830	ENOG4105M2J	Glutaredoxin
THMIRHAS_18840	ENOG4105CAQ	asparagine synthetase
THMIRHAS_18860	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
THMIRHAS_18870	ENOG4105EU8	FAD linked oxidase domain protein
THMIRHAS_18880	ENOG4105CQB	FAD linked oxidase domain protein
THMIRHAS_18890	ENOG4105C5R	Aminotransferase
THMIRHAS_18900	ENOG4105EMU	Dehydrogenase
THMIRHAS_18910	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
THMIRHAS_18920	ENOG4108UB3	Thiamine monophosphate
THMIRHAS_18930	ENOG4105CIH	Imidazole acetol-phosphate transaminase
THMIRHAS_18940	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
THMIRHAS_18950	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
THMIRHAS_18970	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
THMIRHAS_18980	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
THMIRHAS_18990	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
THMIRHAS_19000	ENOG4105CPF	Cell wall formation (By similarity)
THMIRHAS_19010	ENOG4105DFU	Cell wall formation (By similarity)
THMIRHAS_19030	ENOG4105C9B	Cysteine desulfurase
THMIRHAS_19040	ENOG4105JRK	feS assembly protein SufD
THMIRHAS_19050	ENOG4105C3K	feS assembly ATPase SufC
THMIRHAS_19060	ENOG4105DIW	FeS assembly protein SUFB
THMIRHAS_19080	ENOG4105NXV	High-affinity zinc uptake system protein
THMIRHAS_19090	ENOG4105FDK	ABC transporter
THMIRHAS_19100	ENOG4105FAV	ABC, transporter
THMIRHAS_19110	ENOG4105C8Q	Methyl-accepting chemotaxis
THMIRHAS_19120	ENOG4108IJ6	ABC transporter
THMIRHAS_19130	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
THMIRHAS_19140	ENOG4105E0C	molybdate abc transporter
THMIRHAS_19170	ENOG4105X1Q	TOBE domain protein
THMIRHAS_19190	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
THMIRHAS_19230	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
THMIRHAS_19250	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
THMIRHAS_19260	ENOG4105CNI	cell division protein FtsW
THMIRHAS_19270	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
THMIRHAS_19280	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
THMIRHAS_19290	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
THMIRHAS_19300	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
THMIRHAS_19330	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
THMIRHAS_19340	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
THMIRHAS_19390	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
THMIRHAS_19410	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
THMIRHAS_19420	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
THMIRHAS_19430	ENOG41082RQ	UPF0102 protein
THMIRHAS_19450	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
THMIRHAS_19460	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
THMIRHAS_19500	ENOG4105VEQ	Cold shock protein
THMIRHAS_19530	ENOG4105C34	Pseudouridine synthase
THMIRHAS_19560	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
THMIRHAS_19570	ENOG4105CPW	cytochrome b561
THMIRHAS_19580	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
THMIRHAS_19590	ENOG4105D0M	Protease HtpX homolog
THMIRHAS_19600	ENOG4108V0P	LemA family
THMIRHAS_19620	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
THMIRHAS_19640	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
THMIRHAS_19650	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
THMIRHAS_19690	ENOG4105KB2	stringent starvation protein b
THMIRHAS_19700	ENOG4107MKT	Stringent starvation protein a
THMIRHAS_19710	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
THMIRHAS_19720	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
THMIRHAS_19730	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
THMIRHAS_19760	ENOG4105CGY	Dna recombination protein
THMIRHAS_19810	ENOG4107QHF	type ii secretion system protein e
THMIRHAS_19860	ENOG4105C03	ribonuclease
THMIRHAS_19870	ENOG4108Z03	MAF-like protein
THMIRHAS_19900	ENOG4105CKK	Glycosyl transferase, family 2
THMIRHAS_19960	ENOG4105D16	lipopolysaccharide heptosyltransferase i
THMIRHAS_19980	ENOG4105BZ1	(ABC) transporter
THMIRHAS_19990	ENOG4105D1S	lipid A biosynthesis
THMIRHAS_20000	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
THMIRHAS_20010	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
THMIRHAS_20030	ENOG4105CM2	brancheD-chain amino acid aminotransferase
THMIRHAS_20050	ENOG4105C8Y	Acetylornithine aminotransferase
THMIRHAS_20060	ENOG4105DBV	ornithine carbamoyltransferase
THMIRHAS_20160	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
THMIRHAS_20170	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
THMIRHAS_20180	ENOG4107QMP	dna polymerase iii subunits gamma and tau
THMIRHAS_20300	ENOG4105BZS	acriflavin resistance protein
THMIRHAS_20330	ENOG4105DHZ	alpha beta
THMIRHAS_20340	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
THMIRHAS_20400	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
THMIRHAS_20410	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
THMIRHAS_20420	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
THMIRHAS_20430	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
THMIRHAS_20440	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
THMIRHAS_20450	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
THMIRHAS_20460	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
THMIRHAS_20470	ENOG4105DC1	bifunctional purine biosynthesis protein purh
THMIRHAS_20520	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
THMIRHAS_20530	ENOG41060IM	Heme exporter protein
THMIRHAS_20540	ENOG4105X3C	heme exporter protein
THMIRHAS_20550	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
THMIRHAS_20560	ENOG4105DA4	cytochrome c-type biogenesis protein
THMIRHAS_20570	ENOG4107QX9	Thiol disulfide interChange protein
THMIRHAS_20580	ENOG4105KWW	Biogenesis protein
THMIRHAS_20590	ENOG4108M1T	Cytochrome c-type biogenesis protein
THMIRHAS_20600	ENOG4105CUW	cytochrome C-TYPE protein
THMIRHAS_20610	ENOG4105MW3	Cytochrome
THMIRHAS_20620	ENOG4107S7U	Sulfide dehydrogenase
THMIRHAS_20630	ENOG4107S7U	Sulfide dehydrogenase
THMIRHAS_20660	ENOG4107S7U	Sulfide dehydrogenase
THMIRHAS_20670	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
THMIRHAS_20690	ENOG4105D4P	Coproporphyrinogen iii oxidase
THMIRHAS_20700	ENOG4105BZU	Histidine kinase
THMIRHAS_20710	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
THMIRHAS_20720	ENOG4105CVE	Lytic murein transglycosylase
THMIRHAS_20750	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
THMIRHAS_20760	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
THMIRHAS_20770	ENOG4105DTN	riboflavin biosynthesis protein ribF
THMIRHAS_20780	ENOG4105CJR	Integral membrane protein (MviN
THMIRHAS_20810	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
THMIRHAS_20820	ENOG4107R0U	MotA TolQ exbB proton channel
THMIRHAS_20830	ENOG4106VK6	Flagellar motor protein
THMIRHAS_20840	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
THMIRHAS_20850	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
THMIRHAS_20860	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
THMIRHAS_20870	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
THMIRHAS_20900	ENOG4105C8T	Leucyl-tRNA synthetase
THMIRHAS_20920	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
THMIRHAS_20930	ENOG4108JU5	Magnesium and cobalt efflux protein
THMIRHAS_20940	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
THMIRHAS_20950	ENOG4105C9A	Phoh family
THMIRHAS_20960	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
THMIRHAS_20980	ENOG4105BZU	Histidine kinase
THMIRHAS_20990	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
THMIRHAS_21030	ENOG4108VAU	general secretion pathway protein G
THMIRHAS_21050	ENOG4108Z9W	Outer membrane porin
THMIRHAS_21060	ENOG4108UJD	30S ribosomal protein S9
THMIRHAS_21070	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
THMIRHAS_21080	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THMIRHAS_21090	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
THMIRHAS_21100	ENOG4105KTH	gatB Yqey
THMIRHAS_21110	ENOG4105VCC	30S ribosomal protein S21
THMIRHAS_21120	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
THMIRHAS_21130	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
THMIRHAS_21140	ENOG4107ZVW	dihydroneopterin aldolase
THMIRHAS_21180	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
THMIRHAS_21200	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
THMIRHAS_21210	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
THMIRHAS_21220	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
THMIRHAS_21240	ENOG4105BZU	Histidine kinase
THMIRHAS_21250	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
THMIRHAS_21260	ENOG4105SYT	Methylenetetrahydrofolate reductase
THMIRHAS_21270	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
THMIRHAS_21290	ENOG4105D7Z	glutathione synthase
THMIRHAS_21300	ENOG41081YB	ApbE family
THMIRHAS_21310	ENOG4108UJU	UPF0301 protein
THMIRHAS_21320	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
THMIRHAS_21330	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
THMIRHAS_21340	ENOG4105CXT	aspartate transcarbamylase
THMIRHAS_21350	ENOG4105CD3	dihydroorotase
THMIRHAS_21390	ENOG4105CSR	polyphosphate kinase 2
THMIRHAS_21400	ENOG4105DFA	alanine racemase domain protein
THMIRHAS_21420	ENOG4105II7	pyrroline-5-carboxylate reductase
THMIRHAS_21430	ENOG4108VIA	integral membrane protein
THMIRHAS_21440	ENOG4105DWV	Homoserine O-trans-acetylase
THMIRHAS_21470	ENOG4105CE1	Ferrous iron transport protein b
THMIRHAS_21500	ENOG4105PYN	Pyridoxamine 5-phosphate oxidase-related
THMIRHAS_21510	ENOG4106CJB	Phospholipase Carboxylesterase
THMIRHAS_21530	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
THMIRHAS_21560	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
THMIRHAS_21580	ENOG4105BZU	Histidine kinase
THMIRHAS_21590	ENOG4108XDN	Transcriptional regulator
THMIRHAS_21600	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
THMIRHAS_21660	ENOG4107FW0	short-chain dehydrogenase reductase
THMIRHAS_21680	ENOG4105CT4	transporter
THMIRHAS_21690	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THMIRHAS_21700	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
THMIRHAS_21710	ENOG4105BZU	Histidine kinase
THMIRHAS_21790	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
THMIRHAS_21800	ENOG4105BZN	citrate synthase
THMIRHAS_21810	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
THMIRHAS_21820	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
THMIRHAS_21830	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
THMIRHAS_21840	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
THMIRHAS_21860	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
THMIRHAS_21870	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
THMIRHAS_21890	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
THMIRHAS_21900	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
THMIRHAS_21910	ENOG4105K46	50S ribosomal protein l27
THMIRHAS_21920	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
THMIRHAS_21930	ENOG4105EAH	synthase
THMIRHAS_21950	ENOG4108UUM	single-stranded DNA-binding protein
THMIRHAS_21960	ENOG4107RDB	Major Facilitator
THMIRHAS_21980	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
THMIRHAS_22000	ENOG4105CHC	glucokinase (EC 2.7.1.2)
THMIRHAS_22010	ENOG4105CUZ	uba thif-type nad fad binding protein
THMIRHAS_22030	ENOG4108ZT0	50S ribosomal protein l17
THMIRHAS_22040	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
THMIRHAS_22050	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
THMIRHAS_22060	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
THMIRHAS_22070	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
THMIRHAS_22080	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
THMIRHAS_22090	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
THMIRHAS_22100	ENOG4105VPB	50S ribosomal protein L30
THMIRHAS_22110	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
THMIRHAS_22120	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
THMIRHAS_22130	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
THMIRHAS_22140	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
THMIRHAS_22150	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
THMIRHAS_22160	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
THMIRHAS_22170	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
THMIRHAS_22180	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
THMIRHAS_22190	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
THMIRHAS_22200	ENOG41083MP	50s ribosomal protein l29
THMIRHAS_22210	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
THMIRHAS_22220	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
THMIRHAS_22230	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
THMIRHAS_22240	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
THMIRHAS_22250	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
THMIRHAS_22260	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
THMIRHAS_22270	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
THMIRHAS_22280	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
THMIRHAS_22290	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
THMIRHAS_22300	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
THMIRHAS_22310	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
THMIRHAS_22320	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
THMIRHAS_22330	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
THMIRHAS_22340	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
THMIRHAS_22350	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
THMIRHAS_22360	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
THMIRHAS_22370	ENOG4108VZM	50s ribosomal protein L10
THMIRHAS_22380	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
THMIRHAS_22390	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
THMIRHAS_22400	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
THMIRHAS_22410	ENOG4105PM1	preprotein translocase subunit SecE
THMIRHAS_22420	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
THMIRHAS_22440	ENOG4105DR9	pseudouridine synthase
THMIRHAS_22450	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
THMIRHAS_22520	ENOG4105CD3	dihydroorotase
THMIRHAS_22530	ENOG4105BZU	Histidine kinase
THMIRHAS_22540	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
THMIRHAS_22560	ENOG4105C9X	ppx gppa phosphatase
THMIRHAS_22570	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
THMIRHAS_22600	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
THMIRHAS_22610	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
THMIRHAS_22620	ENOG4105CDV	Ompa motb domain protein
THMIRHAS_22640	ENOG4105D64	Mechanosensitive ion channel
THMIRHAS_22650	ENOG4105CAS	nag kinase
THMIRHAS_22660	ENOG4108VPT	UPF0234 protein
THMIRHAS_22720	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
THMIRHAS_22730	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
THMIRHAS_22750	ENOG4107T8V	it plays a direct role in the translocation of protons across the membrane (By similarity)
THMIRHAS_22770	ENOG4108Q71	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
THMIRHAS_22800	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
THMIRHAS_22820	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
THMIRHAS_22830	ENOG4105BZU	Histidine kinase
THMIRHAS_22850	ENOG4105EW6	flavin reductase domain protein, FMN-binding
THMIRHAS_22860	ENOG4107Y2X	deaminase
THMIRHAS_22880	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
THMIRHAS_22900	ENOG4105C8Q	Methyl-accepting chemotaxis
THMIRHAS_22910	ENOG4107S7U	Sulfide dehydrogenase
THMIRHAS_22940	ENOG4105W5Q	DNA repair protein (RadC
THMIRHAS_22980	ENOG4105KDC	50s ribosomal protein l28
THMIRHAS_22990	ENOG4105W0E	50S ribosomal protein L33
THMIRHAS_23020	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
THMIRHAS_23040	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
THMIRHAS_23050	ENOG4105E0C	molybdate abc transporter
THMIRHAS_23060	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
THMIRHAS_23070	ENOG4105F4R	Transcriptional regulator mode
THMIRHAS_23100	ENOG4105D3R	alkyl hydroperoxide reductase
THMIRHAS_23110	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
THMIRHAS_23120	ENOG4106H78	methyltransferase
THMIRHAS_23140	ENOG4105BZU	Histidine kinase
THMIRHAS_23180	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
THMIRHAS_23220	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
THMIRHAS_23230	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
THMIRHAS_23250	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
THMIRHAS_23260	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
THMIRHAS_23270	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
THMIRHAS_23280	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
THMIRHAS_23290	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
THMIRHAS_23300	ENOG4105VW4	glutaredoxin 3
THMIRHAS_23320	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
THMIRHAS_23330	ENOG4105CBC	glutamate synthase
THMIRHAS_23340	ENOG4105BZ8	glutamate synthase
THMIRHAS_23370	ENOG4105C5I	Dehydrogenase
THMIRHAS_23390	ENOG4105CH5	extracellular solute-binding protein, family 7
THMIRHAS_23400	ENOG4105C8Q	Methyl-accepting chemotaxis
THMIRHAS_23430	ENOG4105D05	Receptor
THMIRHAS_23450	ENOG4107QX9	Thiol disulfide interChange protein
THMIRHAS_23460	ENOG4105C4B	ABC transporter, permease
THMIRHAS_23480	ENOG41083J0	(ABC) transporter
THMIRHAS_23490	ENOG4105C4R	Atp-dependent dna helicase
THMIRHAS_23500	ENOG4105K63	Thioredoxin
THMIRHAS_23510	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
THMIRHAS_23520	ENOG4105NRA	50s ribosomal protein l31 type b
THMIRHAS_23540	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
THMIRHAS_23560	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
THMIRHAS_23570	ENOG4105CEN	a g-specific adenine glycosylase
THMIRHAS_23580	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
THMIRHAS_23600	ENOG4105CSA	Coproporphyrinogen iii oxidase
THMIRHAS_23610	ENOG4105C2C	drug resistance transporter, Bcr CflA
THMIRHAS_23620	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
THMIRHAS_23630	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
THMIRHAS_23640	ENOG4105DSJ	YicC domain protein
THMIRHAS_23770	ENOG4108JQC	penicillin-binding protein 1A
THMIRHAS_23790	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
THMIRHAS_23840	ENOG4105EB3	Histidine kinase
THMIRHAS_23850	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
THMIRHAS_23860	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
THMIRHAS_23870	ENOG4105BZS	acriflavin resistance protein
THMIRHAS_23880	ENOG4105BZU	Histidine kinase
THMIRHAS_23930	ENOG4105E5H	Transposase
THMIRHAS_24010	ENOG4105CTK	cobaltochelatase, cobn subunit
THMIRHAS_24020	ENOG4105D05	Receptor
THMIRHAS_24030	ENOG4105CTK	cobaltochelatase, cobn subunit
THMIRHAS_24060	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
THMIRHAS_24070	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
THMIRHAS_24090	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
THMIRHAS_24100	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
THMIRHAS_24110	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
THMIRHAS_24140	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
THMIRHAS_24150	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
THMIRHAS_24160	ENOG4105BZU	Histidine kinase
THMIRHAS_24180	ENOG4105EUB	pirin domain protein
THMIRHAS_24190	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
THMIRHAS_24200	ENOG4105EXG	Transcriptional regulator
THMIRHAS_24210	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
THMIRHAS_24210	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
THMIRHAS_24270	ENOG4105C8Q	Methyl-accepting chemotaxis
THMIRHAS_24310	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
THMIRHAS_24360	ENOG4105KNY	Microcompartments protein
THMIRHAS_24370	ENOG4105KNY	Microcompartments protein
THMIRHAS_24380	ENOG4105KNY	Microcompartments protein
THMIRHAS_24440	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
THMIRHAS_24480	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
THMIRHAS_24500	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THMIRHAS_24510	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
THMIRHAS_24520	ENOG4105C87	Aminotransferase class I and II
THMIRHAS_24550	ENOG4105DSB	aldose 1-epimerase
THMIRHAS_24560	ENOG4105D49	3-dehydroquinate synthase
THMIRHAS_24570	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
THMIRHAS_24580	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
THMIRHAS_24590	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
THMIRHAS_24600	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
THMIRHAS_24610	ENOG4105KME	endoribonuclease L-psp
THMIRHAS_24620	ENOG4105DQF	Hydrolase
THMIRHAS_24630	ENOG4105CB5	ATP-dependent DNA helicase recG
THMIRHAS_24640	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
THMIRHAS_24670	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
THMIRHAS_24690	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
THMIRHAS_24700	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
THMIRHAS_24710	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
THMIRHAS_24720	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
THMIRHAS_24730	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
THMIRHAS_24740	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
THMIRHAS_24750	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
THMIRHAS_24760	ENOG41081A3	ATP synthase f0, c subunit
THMIRHAS_24770	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
THMIRHAS_24810	ENOG4107QJE	Chromosome Partitioning Protein
THMIRHAS_24820	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
THMIRHAS_24830	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
THMIRHAS_24860	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
THMIRHAS_24880	ENOG4105DGU	Histone deacetylase
THMIRHAS_24890	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
THMIRHAS_24900	ENOG4105BZS	acriflavin resistance protein
THMIRHAS_24930	ENOG4105C8Q	Methyl-accepting chemotaxis
THMIRHAS_24950	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
THMIRHAS_24960	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
THMIRHAS_24980	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
THMIRHAS_24990	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
THMIRHAS_25000	ENOG4105VG0	50S ribosomal protein l34