locus-tag	class	description
HQN79_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HQN79_00010	COG0592	DNA-directed DNA polymerase activity
HQN79_00015	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
HQN79_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HQN79_00030	COG0187	DNA topoisomerase II activity
HQN79_00040	COG2111	Na H antiporter
HQN79_00040	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HQN79_00045	COG1006	Multisubunit Na H antiporter MnhC subunit
HQN79_00050	COG0651	ATP synthesis coupled electron transport
HQN79_00060	COG2212	antiporter activity
HQN79_00065	COG1320	monovalent cation:proton antiporter activity
HQN79_00075	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HQN79_00080	COG0408	coproporphyrinogen oxidase activity
HQN79_00095	COG0009	L-threonylcarbamoyladenylate synthase
HQN79_00100	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HQN79_00105	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HQN79_00105	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HQN79_00120	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HQN79_00125	COG1333	cytochrome c biogenesis protein
HQN79_00130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HQN79_00135	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HQN79_00150	COG0778	Nitroreductase
HQN79_00170	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HQN79_00175	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HQN79_00180	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HQN79_00185	COG0363	glucosamine-6-phosphate deaminase activity
HQN79_00205	COG1136	(ABC) transporter
HQN79_00230	COG0432	Pfam Uncharacterised protein family UPF0047
HQN79_00240	COG0339	signal peptide processing
HQN79_00260	COG1595	DNA-templated transcription, initiation
HQN79_00305	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HQN79_00310	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HQN79_00340	COG3038	cytochrome b561
HQN79_00345	COG0583	DNA-binding transcription factor activity
HQN79_00365	COG0123	including yeast histone deacetylase and acetoin utilization protein
HQN79_00395	COG0714	Associated with various cellular activities
HQN79_00415	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HQN79_00430	COG2226	methyltransferase
HQN79_00440	COG0500	methyltransferase
HQN79_00510	COG2363	Small membrane protein
HQN79_00520	COG2354	Protein conserved in bacteria
HQN79_00545	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HQN79_00550	COG2814	Major facilitator Superfamily
HQN79_00555	COG0714	Associated with various cellular activities
HQN79_00590	COG3118	belongs to the thioredoxin family
HQN79_00615	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HQN79_00620	COG0165	Argininosuccinate lyase
HQN79_00630	COG0181	hydroxymethylbilane synthase activity
HQN79_00670	COG0708	Exodeoxyribonuclease III
HQN79_00680	COG0788	formyltetrahydrofolate deformylase activity
HQN79_00685	COG1444	tRNA N-acetyltransferase activity
HQN79_00690	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HQN79_00695	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HQN79_00695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HQN79_00705	COG0351	phosphomethylpyrimidine kinase
HQN79_00715	COG2081	HI0933 family
HQN79_00725	COG0678	peroxiredoxin activity
HQN79_00725	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HQN79_00745	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HQN79_00750	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HQN79_00780	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HQN79_00785	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HQN79_00790	COG0314	molybdopterin synthase activity
HQN79_00795	COG0303	'Molybdopterin
HQN79_00800	COG0450	alkyl hydroperoxide reductase
HQN79_00805	COG3128	pkhd-type hydroxylase
HQN79_00810	COG1304	FMN binding
HQN79_00815	COG4774	siderophore transport
HQN79_00820	COG0315	cyclic pyranopterin monophosphate synthase activity
HQN79_00825	COG5001	Diguanylate cyclase
HQN79_00825	COG5002	protein histidine kinase activity
HQN79_00860	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HQN79_00865	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
HQN79_00885	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HQN79_00890	COG2226	methyltransferase
HQN79_00905	COG1115	amino acid carrier protein
HQN79_00920	COG2308	Evidence 4 Homologs of previously reported genes of
HQN79_00930	COG0156	8-amino-7-oxononanoate synthase activity
HQN79_00935	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HQN79_00940	COG1040	competence protein
HQN79_00945	COG1230	cation diffusion facilitator family transporter
HQN79_00955	COG1331	Highly conserved protein containing a thioredoxin domain
HQN79_00965	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HQN79_00970	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HQN79_00975	COG0537	adenosine 5'-monophosphoramidase activity
HQN79_00980	COG0140	phosphoribosyl-ATP diphosphatase activity
HQN79_00985	COG0107	imidazoleglycerol-phosphate synthase activity
HQN79_00990	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HQN79_00995	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HQN79_01000	COG0131	Imidazoleglycerol-phosphate dehydratase
HQN79_01005	COG3278	Belongs to the heme-copper respiratory oxidase family
HQN79_01020	COG2010	Cytochrome c
HQN79_01030	COG0348	domain, Protein
HQN79_01040	COG2217	Heavy metal translocating P-type atpase
HQN79_01075	COG5001	Diguanylate cyclase
HQN79_01075	COG3300	MHYT domain
HQN79_01080	COG1490	D-aminoacyl-tRNA deacylase activity
HQN79_01090	COG1217	gtp-binding protein TYPA
HQN79_01100	COG2391	methyltransferase activity
HQN79_01175	COG0281	malic enzyme
HQN79_01185	COG0840	transmembrane signaling receptor activity
HQN79_01185	COG0840	transmembrane signaling receptor activity
HQN79_01190	COG0513	Belongs to the DEAD box helicase family
HQN79_01200	COG4628	conserved protein (DUF2132)
HQN79_01220	COG0646	methionine synthase
HQN79_01220	COG1410	methionine synthase
HQN79_01230	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HQN79_01245	COG0840	transmembrane signaling receptor activity
HQN79_01265	COG0037	tRNA processing
HQN79_01280	COG0330	HflC and HflK could
HQN79_01290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HQN79_01295	COG0569	domain protein
HQN79_01300	COG2204	response regulator
HQN79_01305	COG5000	phosphorelay sensor kinase activity
HQN79_01315	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HQN79_01315	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HQN79_01320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HQN79_01325	COG0242	peptide deformylase activity
HQN79_01330	COG0758	DNA mediated transformation
HQN79_01335	COG1754	DNA topoisomerase type I activity
HQN79_01335	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HQN79_01340	COG0018	arginyl-trna synthetase
HQN79_01350	COG2199	diguanylate cyclase activity
HQN79_01360	COG0606	chelatase, subunit chli
HQN79_01375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HQN79_01390	COG1028	Short-chain dehydrogenase reductase Sdr
HQN79_01410	COG0778	Nitroreductase
HQN79_01410	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
HQN79_01415	COG2239	Acts as a magnesium transporter
HQN79_01430	COG0306	phosphate transporter
HQN79_01435	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
HQN79_01455	COG0493	'glutamate synthase
HQN79_01460	COG0070	glutamate synthase
HQN79_01460	COG0069	glutamate synthase activity
HQN79_01460	COG0067	glutamate synthase
HQN79_01465	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HQN79_01480	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HQN79_01485	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HQN79_01490	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HQN79_01495	COG0167	dihydroorotate dehydrogenase activity
HQN79_01500	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HQN79_01535	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HQN79_01545	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HQN79_01565	COG0552	protein localization to endoplasmic reticulum
HQN79_01570	COG0612	Peptidase, M16
HQN79_01575	COG0612	Peptidase, M16
HQN79_01585	COG0583	DNA-binding transcription factor activity
HQN79_01590	COG0742	ribosomal rna small subunit methyltransferase
HQN79_01600	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HQN79_01605	COG0450	alkyl hydroperoxide reductase
HQN79_01640	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HQN79_01655	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HQN79_01660	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HQN79_01675	COG2003	Belongs to the UPF0758 family
HQN79_01690	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQN79_01700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HQN79_01705	COG1760	l-serine dehydratase
HQN79_01710	COG0438	transferase activity, transferring glycosyl groups
HQN79_01730	COG0033	Phosphoglucomutase
HQN79_01740	COG0756	dUTP diphosphatase activity
HQN79_01750	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HQN79_01760	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQN79_01765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQN79_01775	COG0436	Aminotransferase
HQN79_01780	COG1666	GTP binding
HQN79_01785	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HQN79_01790	COG0668	transmembrane transport
HQN79_01815	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
HQN79_01825	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HQN79_01840	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HQN79_01860	COG1012	belongs to the aldehyde dehydrogenase family
HQN79_01880	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HQN79_01885	COG0564	pseudouridine synthase activity
HQN79_01910	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HQN79_01920	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HQN79_01930	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HQN79_01935	COG0081	regulation of translation
HQN79_01940	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HQN79_01945	COG0222	ribosome binding
HQN79_01950	COG0085	RNA polymerase activity
HQN79_01955	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HQN79_01960	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HQN79_01965	COG0049	tRNA binding
HQN79_01970	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HQN79_01975	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HQN79_01980	COG0051	transcription antitermination factor activity, RNA binding
HQN79_01985	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HQN79_01990	COG0088	Forms part of the polypeptide exit tunnel
HQN79_01995	COG0089	rRNA binding
HQN79_02000	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HQN79_02005	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HQN79_02010	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HQN79_02015	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HQN79_02020	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HQN79_02025	COG0255	Belongs to the universal ribosomal protein uL29 family
HQN79_02030	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HQN79_02035	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HQN79_02040	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HQN79_02045	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HQN79_02050	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HQN79_02055	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HQN79_02060	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HQN79_02065	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HQN79_02070	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HQN79_02075	COG1841	ribosomal large subunit assembly
HQN79_02080	COG0200	Binds to the 23S rRNA
HQN79_02085	COG0201	protein transport
HQN79_02090	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HQN79_02095	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HQN79_02100	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HQN79_02105	COG0202	RNA polymerase activity
HQN79_02110	COG0203	ribosomal protein L17
HQN79_02115	COG0084	hydrolase, TatD family'
HQN79_02120	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HQN79_02150	COG2814	Major facilitator Superfamily
HQN79_02155	COG0629	single-stranded DNA binding
HQN79_02165	COG0142	geranyltranstransferase activity
HQN79_02170	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HQN79_02175	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HQN79_02180	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HQN79_02185	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HQN79_02190	COG3706	GGDEF domain
HQN79_02195	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HQN79_02200	COG0459	protein refolding
HQN79_02215	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HQN79_02220	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HQN79_02225	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HQN79_02230	COG0316	Belongs to the HesB IscA family
HQN79_02240	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HQN79_02265	COG2205	protein histidine kinase activity
HQN79_02265	COG3437	response regulator, receiver
HQN79_02265	COG3850	Histidine kinase
HQN79_02265	COG4999	Histidine kinase
HQN79_02275	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HQN79_02285	COG4221	oxidoreductase activity
HQN79_02290	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
HQN79_02300	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HQN79_02305	COG0415	Belongs to the DNA photolyase family
HQN79_02315	COG1366	Belongs to the anti-sigma-factor antagonist family
HQN79_02320	COG0509	glycine decarboxylation via glycine cleavage system
HQN79_02325	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HQN79_02335	COG0019	diaminopimelate decarboxylase activity
HQN79_02340	COG0400	carboxylic ester hydrolase activity
HQN79_02345	COG0748	coenzyme F420 binding
HQN79_02360	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
HQN79_02370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HQN79_02370	COG2813	Specifically methylates the guanine in position
HQN79_02375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HQN79_02400	COG2326	polyphosphate kinase activity
HQN79_02420	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HQN79_02425	COG0540	Belongs to the ATCase OTCase family
HQN79_02430	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HQN79_02435	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HQN79_02440	COG1678	Uncharacterized ACR, COG1678
HQN79_02450	COG0189	ligase activity
HQN79_02460	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HQN79_02465	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HQN79_02470	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HQN79_02475	COG5001	Diguanylate cyclase
HQN79_02475	COG5002	protein histidine kinase activity
HQN79_02485	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HQN79_02495	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HQN79_02495	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HQN79_02505	COG1968	undecaprenyl-diphosphatase activity
HQN79_02525	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HQN79_02530	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HQN79_02535	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HQN79_02540	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HQN79_02545	COG1610	YqeY-like protein
HQN79_02550	COG0358	DNA primase activity
HQN79_02605	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HQN79_02610	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HQN79_02650	COG0745	RESPONSE REGULATOR receiver
HQN79_02665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HQN79_02670	COG1702	phosphate starvation-inducible protein PhoH
HQN79_02675	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HQN79_02680	COG4535	Mg2 and Co2 transporter CorC
HQN79_02685	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HQN79_02695	COG0495	leucyl-tRNA aminoacylation
HQN79_02710	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HQN79_02715	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HQN79_02720	COG0799	negative regulation of ribosome biogenesis
HQN79_02725	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HQN79_02735	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQN79_02740	COG0268	Binds directly to 16S ribosomal RNA
HQN79_02745	COG0028	Belongs to the TPP enzyme family
HQN79_02755	COG0196	riboflavin kinase activity
HQN79_02760	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HQN79_02765	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HQN79_02780	COG2951	lytic endotransglycosylase activity
HQN79_02785	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HQN79_02785	COG0116	Belongs to the methyltransferase superfamily
HQN79_02800	COG0542	response to heat
HQN79_02805	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQN79_02820	COG0151	Belongs to the GarS family
HQN79_02825	COG0138	bifunctional purine biosynthesis protein purh
HQN79_02830	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HQN79_02835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HQN79_02840	COG2264	protein methyltransferase activity
HQN79_02845	COG0439	Biotin carboxylase
HQN79_02850	COG0511	ligase activity, forming carbon-carbon bonds
HQN79_02855	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HQN79_02860	COG4232	protein-disulfide reductase activity
HQN79_02885	COG3439	Domain of unknown function DUF302
HQN79_02890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HQN79_02935	COG4964	Belongs to the GSP D family
HQN79_02975	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HQN79_02980	COG1116	anion transmembrane transporter activity
HQN79_02985	COG0864	Transcriptional regulator
HQN79_02995	COG3665	Urea carboxylase-associated protein
HQN79_03000	COG0439	Biotin carboxylase
HQN79_03015	COG0837	glucose binding
HQN79_03025	COG0174	glutamine synthetase
HQN79_03055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQN79_03065	COG0531	amino acid
HQN79_03075	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HQN79_03080	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HQN79_03085	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HQN79_03095	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HQN79_03100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HQN79_03115	COG1560	Kdo2-lipid A biosynthetic process
HQN79_03120	COG1132	(ABC) transporter
HQN79_03130	COG3562	capsule polysaccharide
HQN79_03150	COG1442	glycosyl transferase family 8
HQN79_03165	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HQN79_03170	COG0463	Glycosyl transferase, family 2
HQN79_03175	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HQN79_03190	COG0424	maF-like protein
HQN79_03230	COG3409	Peptidoglycan-binding domain 1 protein
HQN79_03230	COG3267	Type II secretory pathway component ExeA
HQN79_03235	COG1450	Type ii and iii secretion system protein
HQN79_03245	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HQN79_03285	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HQN79_03290	COG1509	lysine 2,3-aminomutase activity
HQN79_03295	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HQN79_03305	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HQN79_03310	COG0625	glutathione transferase activity
HQN79_03315	COG2969	positive regulation of protein catabolic process
HQN79_03330	COG0083	homoserine kinase activity
HQN79_03335	COG3425	synthase
HQN79_03340	COG1304	FMN binding
HQN79_03350	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HQN79_03360	COG1704	LemA family
HQN79_03365	COG0501	Belongs to the peptidase M48B family
HQN79_03375	COG0438	transferase activity, transferring glycosyl groups
HQN79_03385	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HQN79_03390	COG3038	cytochrome b561
HQN79_03405	COG0564	pseudouridine synthase activity
HQN79_03425	COG1074	ATP-dependent DNA helicase activity
HQN79_03430	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HQN79_03435	COG0574	Belongs to the PEP-utilizing enzyme family
HQN79_03435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HQN79_03440	COG0792	nuclease activity
HQN79_03445	COG3107	peptidoglycan biosynthetic process
HQN79_03450	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HQN79_03460	COG0742	ribosomal rna small subunit methyltransferase
HQN79_03475	COG2001	Belongs to the MraZ family
HQN79_03480	COG0275	rRNA processing
HQN79_03485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HQN79_03495	COG0768	penicillin binding
HQN79_03500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HQN79_03505	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HQN79_03510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HQN79_03515	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HQN79_03520	COG0772	Belongs to the SEDS family
HQN79_03525	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HQN79_03530	COG1028	Short-chain dehydrogenase reductase Sdr
HQN79_03540	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HQN79_03545	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HQN79_03555	COG0840	transmembrane signaling receptor activity
HQN79_03560	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HQN79_03565	COG1121	(ABC) transporter
HQN79_03580	COG0719	Fe-S assembly protein
HQN79_03585	COG0396	ATPase activity
HQN79_03590	COG0719	Fe-S assembly protein
HQN79_03595	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HQN79_03605	COG1538	Outer membrane efflux protein
HQN79_03615	COG0577	efflux transmembrane transporter activity
HQN79_03615	COG1136	(ABC) transporter
HQN79_03620	COG0577	efflux transmembrane transporter activity
HQN79_03620	COG1136	(ABC) transporter
HQN79_03625	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HQN79_03630	COG1181	Belongs to the D-alanine--D-alanine ligase family
HQN79_03635	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HQN79_03645	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HQN79_03655	COG0653	protein targeting
HQN79_03660	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HQN79_03665	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HQN79_03670	COG0352	thiamine-phosphate diphosphorylase activity
HQN79_03710	COG4221	oxidoreductase activity
HQN79_03720	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HQN79_03725	COG0277	FAD linked oxidase domain protein
HQN79_03730	COG0277	FAD linked oxidase domain protein
HQN79_03735	COG0247	lactate metabolic process
HQN79_03740	COG2759	Belongs to the formate--tetrahydrofolate ligase family
HQN79_03750	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
HQN79_03765	COG0237	dephospho-CoA kinase activity
HQN79_03765	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HQN79_03770	COG0367	asparagine synthase
HQN79_03775	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HQN79_03780	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HQN79_03785	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HQN79_03785	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HQN79_03790	COG0129	dihydroxy-acid dehydratase activity
HQN79_03800	COG3258	Cytochrome c
HQN79_03820	COG4783	chaperone-mediated protein folding
HQN79_03830	COG2210	Belongs to the sulfur carrier protein TusA family
HQN79_03835	COG1183	phosphatidylcholine synthase activity
HQN79_03840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HQN79_03870	COG1959	2 iron, 2 sulfur cluster binding
HQN79_03875	COG0316	Belongs to the HesB IscA family
HQN79_03880	COG0105	UTP biosynthetic process
HQN79_03885	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HQN79_03895	COG0124	histidyl-tRNA synthetase
HQN79_03905	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HQN79_03910	COG1160	GTP binding
HQN79_03935	COG1162	GTPase activity
HQN79_03940	COG2154	pterin-4-alpha-carbinolamine dehydratase
HQN79_03950	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HQN79_03955	COG0028	Belongs to the TPP enzyme family
HQN79_03965	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HQN79_04000	COG0840	transmembrane signaling receptor activity
HQN79_04035	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQN79_04035	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQN79_04060	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HQN79_04065	COG1741	Belongs to the pirin family
HQN79_04070	COG2863	cytochrome
HQN79_04075	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQN79_04095	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HQN79_04105	COG3201	nicotinamide mononucleotide transporter
HQN79_04135	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HQN79_04140	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HQN79_04145	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HQN79_04150	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HQN79_04155	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HQN79_04160	COG0072	phenylalanine-tRNA ligase activity
HQN79_04160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQN79_04165	COG0776	regulation of translation
HQN79_04200	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HQN79_04205	COG4181	ATPase activity
HQN79_04220	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HQN79_04225	COG0521	Mo-molybdopterin cofactor biosynthetic process
HQN79_04230	COG2890	protein-(glutamine-N5) methyltransferase activity
HQN79_04235	COG3338	carbonate dehydratase activity
HQN79_04245	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HQN79_04250	COG2814	Major facilitator Superfamily
HQN79_04260	COG3123	guanosine phosphorylase activity
HQN79_04265	COG0659	secondary active sulfate transmembrane transporter activity
HQN79_04290	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HQN79_04295	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HQN79_04295	COG1321	iron dependent repressor
HQN79_04300	COG1121	(ABC) transporter
HQN79_04305	COG0803	Belongs to the bacterial solute-binding protein 9 family
HQN79_04310	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HQN79_04320	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HQN79_04325	COG0583	DNA-binding transcription factor activity
HQN79_04330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HQN79_04335	COG0602	queuosine metabolic process
HQN79_04340	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HQN79_04345	COG0066	3-isopropylmalate dehydratase activity
HQN79_04350	COG0473	3-isopropylmalate dehydrogenase activity
HQN79_04355	COG0739	heme binding
HQN79_04365	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HQN79_04370	COG0101	tRNA pseudouridine synthase activity
HQN79_04375	COG0135	phosphoribosylanthranilate isomerase activity
HQN79_04385	COG0159	tryptophan synthase activity
HQN79_04390	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HQN79_04395	COG0285	dihydrofolate synthase activity
HQN79_04415	COG1534	Rna-binding protein
HQN79_04420	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HQN79_04425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HQN79_04430	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HQN79_04435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HQN79_04440	COG0149	triose-phosphate isomerase activity
HQN79_04455	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQN79_04460	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQN79_04465	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQN79_04470	COG0649	NAD binding
HQN79_04485	COG1034	ATP synthesis coupled electron transport
HQN79_04490	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HQN79_04495	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HQN79_04505	COG0713	ATP synthesis coupled electron transport
HQN79_04520	COG1007	ATP synthesis coupled electron transport
HQN79_04530	COG0210	DNA helicase
HQN79_04545	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HQN79_04560	COG3706	GGDEF domain
HQN79_04590	COG1696	Membrane protein involved in D-alanine export
HQN79_04630	COG0582	viral genome integration into host DNA
HQN79_04665	COG0582	viral genome integration into host DNA
HQN79_04685	COG0564	pseudouridine synthase activity
HQN79_04690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HQN79_04695	COG1530	ribonuclease E activity
HQN79_04700	COG0564	pseudouridine synthase activity
HQN79_04705	COG0546	phosphoglycolate phosphatase activity
HQN79_04710	COG0424	maF-like protein
HQN79_04715	COG1399	metal-binding, possibly nucleic acid-binding protein
HQN79_04720	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HQN79_04725	COG0416	fatty acid biosynthetic process
HQN79_04730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HQN79_04735	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HQN79_04745	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HQN79_04750	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HQN79_04755	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HQN79_04765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HQN79_04770	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HQN79_04780	COG0084	hydrolase, TatD family'
HQN79_04810	COG0840	transmembrane signaling receptor activity
HQN79_04810	COG0840	transmembrane signaling receptor activity
HQN79_04850	COG1304	FMN binding
HQN79_04880	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
HQN79_04900	COG1269	ATP hydrolysis coupled proton transport
HQN79_04905	COG1394	ATPase activity, coupled to movement of substances
HQN79_04965	COG0582	viral genome integration into host DNA
HQN79_04975	COG3706	GGDEF domain
HQN79_04980	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HQN79_05010	COG0497	DNA recombination
HQN79_05015	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HQN79_05020	COG1420	regulation of RNA biosynthetic process
HQN79_05025	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HQN79_05030	COG0443	Heat shock 70 kDa protein
HQN79_05035	COG0484	heat shock protein binding
HQN79_05040	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HQN79_05045	COG0791	NLP P60 protein
HQN79_05050	COG0505	Belongs to the CarA family
HQN79_05060	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HQN79_05070	COG2833	Protein of unknown function (DUF455)
HQN79_05075	COG1940	carbohydrate kinase activity
HQN79_05085	COG0300	oxidoreductase activity
HQN79_05090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HQN79_05100	COG2197	response regulator
HQN79_05115	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HQN79_05125	COG0835	chemotaxis
HQN79_05140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HQN79_05145	COG0481	GTPase activity
HQN79_05155	COG0571	ribonuclease III activity
HQN79_05160	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HQN79_05170	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HQN79_05175	COG0736	holo-[acyl-carrier-protein] synthase activity
HQN79_05205	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HQN79_05210	COG2755	lipolytic protein G-D-S-L family
HQN79_05220	COG1252	NADH dehydrogenase
HQN79_05230	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HQN79_05245	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HQN79_05250	COG0004	ammonium transporteR
HQN79_05255	COG1067	ATP-dependent peptidase activity
HQN79_05265	COG2333	competence protein COMEC
HQN79_05265	COG0658	competence protein
HQN79_05270	COG1663	tetraacyldisaccharide 4'-kinase activity
HQN79_05275	COG2835	tetraacyldisaccharide 4'-kinase activity
HQN79_05280	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HQN79_05290	COG2814	Major facilitator Superfamily
HQN79_05295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HQN79_05300	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HQN79_05305	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HQN79_05305	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HQN79_05315	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HQN79_05315	COG3264	Mechanosensitive ion channel
HQN79_05325	COG3706	GGDEF domain
HQN79_05330	COG1492	cobalamin metabolic process
HQN79_05335	COG4772	TonB-dependent receptor
HQN79_05345	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HQN79_05350	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HQN79_05360	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HQN79_05365	COG2255	four-way junction helicase activity
HQN79_05375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HQN79_05390	COG1280	lysine exporter protein (LysE YggA)
HQN79_05405	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HQN79_05415	COG1131	(ABC) transporter
HQN79_05420	COG0842	Transport permease protein
HQN79_05425	COG0842	Transport permease protein
HQN79_05450	COG1404	Belongs to the peptidase S8 family
HQN79_05455	COG0328	RNA-DNA hybrid ribonuclease activity
HQN79_05465	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HQN79_05475	COG4660	Part of a membrane complex involved in electron transport
HQN79_05480	COG4659	FMN binding
HQN79_05485	COG4658	electron transport chain
HQN79_05490	COG4656	Part of a membrane complex involved in electron transport
HQN79_05495	COG2878	Part of a membrane complex involved in electron transport
HQN79_05500	COG4657	Part of a membrane complex involved in electron transport
HQN79_05505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQN79_05505	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HQN79_05510	COG0489	protein tyrosine kinase activity
HQN79_05520	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HQN79_05525	COG1923	regulation of RNA biosynthetic process
HQN79_05530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HQN79_05535	COG0330	HflC and HflK could
HQN79_05540	COG0330	HflC and HflK could
HQN79_05550	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HQN79_05555	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HQN79_05560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HQN79_05570	COG2915	High frequency lysogenization protein hflD homolog
HQN79_05575	COG0482	sulfurtransferase activity
HQN79_05580	COG1187	pseudouridine synthase activity
HQN79_05595	COG0217	transcriptional regulatory protein
HQN79_05600	COG2824	Alkylphosphonate utilization operon protein PhnA
HQN79_05610	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HQN79_05615	COG0542	response to heat
HQN79_05620	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HQN79_05630	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HQN79_05635	COG1053	succinate dehydrogenase
HQN79_05650	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HQN79_05660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HQN79_05680	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HQN79_05685	COG0779	Required for maturation of 30S ribosomal subunits
HQN79_05690	COG0195	Participates in both transcription termination and antitermination
HQN79_05695	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HQN79_05700	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HQN79_05705	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HQN79_05710	COG0500	methyltransferase
HQN79_05720	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HQN79_05730	COG1185	polyribonucleotide nucleotidyltransferase activity
HQN79_05740	COG4943	cyclic-guanylate-specific phosphodiesterase activity
HQN79_05760	COG2850	peptidyl-arginine hydroxylation
HQN79_05770	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HQN79_05785	COG1049	propionate catabolic process, 2-methylcitrate cycle
HQN79_05795	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HQN79_05800	COG0544	peptidyl-prolyl cis-trans isomerase activity
HQN79_05805	COG0740	serine-type endopeptidase activity
HQN79_05810	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HQN79_05815	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HQN79_05860	COG0747	negative chemotaxis
HQN79_05865	COG0601	transmembrane transport
HQN79_05870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQN79_05880	COG4221	oxidoreductase activity
HQN79_05890	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HQN79_05900	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HQN79_05910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HQN79_05915	COG0287	Prephenate dehydrogenase
HQN79_05920	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HQN79_05925	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HQN79_05935	COG0776	regulation of translation
HQN79_05940	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HQN79_05950	COG0284	orotidine-5'-phosphate decarboxylase activity
HQN79_05955	COG0360	Binds together with S18 to 16S ribosomal RNA
HQN79_05960	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HQN79_05970	COG0359	binds to the 23S rRNA
HQN79_05975	COG0305	Participates in initiation and elongation during chromosome replication
HQN79_05980	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HQN79_05995	COG0534	Mate efflux family protein
HQN79_06000	COG3012	SEC-C Motif Domain Protein
HQN79_06015	COG0745	RESPONSE REGULATOR receiver
HQN79_06025	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
HQN79_06070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQN79_06090	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HQN79_06100	COG0697	spore germination
HQN79_06110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HQN79_06115	COG2350	Protein conserved in bacteria
HQN79_06120	COG2917	probably involved in intracellular septation
HQN79_06125	COG0613	PHP domain protein
HQN79_06130	COG0009	L-threonylcarbamoyladenylate synthase
HQN79_06135	COG1994	Peptidase M50
HQN79_06140	COG1187	pseudouridine synthase activity
HQN79_06165	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HQN79_06200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HQN79_06215	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HQN79_06220	COG1570	exodeoxyribonuclease VII activity
HQN79_06230	COG1393	Belongs to the ArsC family
HQN79_06240	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HQN79_06255	COG0436	Aminotransferase
HQN79_06270	COG1238	metal cluster binding
HQN79_06275	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HQN79_06280	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HQN79_06285	COG2840	Smr protein MutS2
HQN79_06295	COG0148	phosphopyruvate hydratase activity
HQN79_06300	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HQN79_06305	COG0504	CTP synthase activity
HQN79_06310	COG0037	tRNA processing
HQN79_06315	COG0825	malonyl-CoA metabolic process
HQN79_06325	COG1944	ATP diphosphatase activity
HQN79_06345	COG1214	PFAM Peptidase M22, glycoprotease
HQN79_06350	COG1199	ATP-dependent helicase activity
HQN79_06355	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HQN79_06430	COG0582	viral genome integration into host DNA
HQN79_06435	COG0835	chemotaxis
HQN79_06435	COG0784	Response regulator, receiver
HQN79_06440	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HQN79_06445	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQN79_06450	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQN79_06455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HQN79_06460	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQN79_06470	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HQN79_06480	COG0575	Belongs to the CDS family
HQN79_06490	COG0233	cytoplasmic translational termination
HQN79_06495	COG0528	UMP kinase activity
HQN79_06500	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HQN79_06505	COG0052	Belongs to the universal ribosomal protein uS2 family
HQN79_06510	COG0024	Methionine aminopeptidase
HQN79_06515	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HQN79_06525	COG2171	N-acyltransferase activity
HQN79_06530	COG1393	Belongs to the ArsC family
HQN79_06535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HQN79_06545	COG3706	GGDEF domain
HQN79_06545	COG2203	Gaf domain
HQN79_06545	COG4251	negative regulation of phosphorylation
HQN79_06545	COG5001	Diguanylate cyclase
HQN79_06580	COG0322	excinuclease ABC activity
HQN79_06585	COG0616	signal peptide processing
HQN79_06590	COG0488	(ABC) transporter
HQN79_06595	COG1136	(ABC) transporter
HQN79_06610	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQN79_06620	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HQN79_06640	COG2022	thiamine diphosphate biosynthetic process
HQN79_06655	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HQN79_06670	COG0733	neurotransmitter:sodium symporter activity
HQN79_06685	COG0668	transmembrane transport
HQN79_06690	COG1472	Belongs to the glycosyl hydrolase 3 family
HQN79_06700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQN79_06705	COG0601	transmembrane transport
HQN79_06720	COG1355	regulation of microtubule-based process
HQN79_06735	COG1538	Outer membrane efflux protein
HQN79_06740	COG2954	triphosphatase activity
HQN79_06755	COG0840	transmembrane signaling receptor activity
HQN79_06765	COG3585	molybdate ion transport
HQN79_06785	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HQN79_06790	COG0826	peptidase U32
HQN79_06805	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HQN79_06815	COG4206	TonB-dependent receptor
HQN79_06820	COG1981	membrane
HQN79_06825	COG1047	Peptidyl-prolyl cis-trans
HQN79_06835	COG2983	Belongs to the UPF0260 family
HQN79_06840	COG0564	pseudouridine synthase activity
HQN79_06895	COG0545	Peptidyl-prolyl cis-trans isomerase
HQN79_06900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HQN79_06905	COG1671	Belongs to the UPF0178 family
HQN79_06910	COG2133	pyrroloquinoline quinone binding
HQN79_06915	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQN79_06940	COG1280	lysine exporter protein (LysE YggA)
HQN79_06945	COG2873	o-acetylhomoserine
HQN79_06960	COG0513	Belongs to the DEAD box helicase family
HQN79_06985	COG0778	Nitroreductase
HQN79_06995	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQN79_07010	COG3384	dioxygenase
HQN79_07020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HQN79_07055	COG1902	pentaerythritol trinitrate reductase activity
HQN79_07060	COG3122	Protein conserved in bacteria
HQN79_07065	COG0513	Belongs to the DEAD box helicase family
HQN79_07085	COG3530	Putative quorum-sensing-regulated virulence factor
HQN79_07090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HQN79_07095	COG0508	dehydrogenase complex catalyzes the overall conversion of
HQN79_07105	COG0840	transmembrane signaling receptor activity
HQN79_07110	COG1051	belongs to the nudix hydrolase family
HQN79_07120	COG0716	FMN binding
HQN79_07150	COG0564	pseudouridine synthase activity
HQN79_07160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HQN79_07160	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HQN79_07170	COG0045	succinate-CoA ligase (ADP-forming) activity
HQN79_07180	COG1047	Peptidyl-prolyl cis-trans
HQN79_07205	COG1643	Atp-dependent helicase
HQN79_07215	COG1047	Peptidyl-prolyl cis-trans
HQN79_07220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HQN79_07225	COG0328	RNA-DNA hybrid ribonuclease activity
HQN79_07230	COG2226	methyltransferase
HQN79_07235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HQN79_07240	COG0741	lytic transglycosylase activity
HQN79_07240	COG1388	LysM domain
HQN79_07245	COG0741	lytic transglycosylase activity
HQN79_07250	COG0215	cysteine-tRNA ligase activity
HQN79_07260	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HQN79_07265	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HQN79_07270	COG1301	dicarboxylic acid transport
HQN79_07280	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HQN79_07305	COG1595	DNA-templated transcription, initiation
HQN79_07315	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
HQN79_07320	COG0137	argininosuccinate synthase activity
HQN79_07325	COG0688	phosphatidylethanolamine metabolic process
HQN79_07330	COG0347	Belongs to the P(II) protein family
HQN79_07335	COG1238	metal cluster binding
HQN79_07340	COG1067	ATP-dependent peptidase activity
HQN79_07350	COG2204	response regulator
HQN79_07355	COG3852	Histidine kinase
HQN79_07370	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HQN79_07375	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
HQN79_07375	COG2199	diguanylate cyclase activity
HQN79_07390	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HQN79_07400	COG2885	chlorophyll binding
HQN79_07405	COG0823	Involved in the tonB-independent uptake of proteins
HQN79_07415	COG0848	biopolymer transport protein
HQN79_07420	COG0811	peptide transport
HQN79_07425	COG2255	four-way junction helicase activity
HQN79_07430	COG0632	four-way junction helicase activity
HQN79_07435	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HQN79_07440	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HQN79_07445	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HQN79_07460	COG0142	geranyltranstransferase activity
HQN79_07465	COG0720	synthase
HQN79_07470	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HQN79_07480	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQN79_07485	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HQN79_07490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HQN79_07495	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HQN79_07510	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HQN79_07510	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HQN79_07515	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HQN79_07520	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HQN79_07525	COG0488	(ABC) transporter
HQN79_07540	COG0840	transmembrane signaling receptor activity
HQN79_07560	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HQN79_07560	COG0047	phosphoribosylformylglycinamidine synthase activity
HQN79_07570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HQN79_07575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HQN79_07580	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HQN79_07585	COG0583	DNA-binding transcription factor activity
HQN79_07590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HQN79_07595	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HQN79_07600	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HQN79_07605	COG0006	proline dipeptidase activity
HQN79_07620	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HQN79_07625	COG0860	N-Acetylmuramoyl-L-alanine amidase
HQN79_07630	COG0802	atpase or kinase
HQN79_07640	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HQN79_07655	COG0442	prolyl-tRNA aminoacylation
HQN79_07665	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HQN79_07705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HQN79_07720	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HQN79_07725	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HQN79_07735	COG0717	Belongs to the dCTP deaminase family
HQN79_07740	COG0189	ligase activity
HQN79_07745	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HQN79_07765	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HQN79_07770	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HQN79_07775	COG0352	thiamine-phosphate diphosphorylase activity
HQN79_07780	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HQN79_07790	COG1643	Atp-dependent helicase
HQN79_07800	COG3101	peptidyl-lysine hydroxylation
HQN79_07820	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HQN79_07830	COG0205	6-phosphofructokinase activity
HQN79_07845	COG3647	Membrane
HQN79_07850	COG0531	amino acid
HQN79_07860	COG4303	Ethanolamine ammonia lyase large subunit
HQN79_07865	COG2207	Transcriptional regulator
HQN79_07870	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HQN79_07870	COG1473	amidohydrolase
HQN79_07880	COG0590	tRNA wobble adenosine to inosine editing
HQN79_07900	COG1538	Outer membrane efflux protein
HQN79_07910	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQN79_07915	COG2197	response regulator
HQN79_07925	COG1132	(ABC) transporter
HQN79_07930	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HQN79_07950	COG0438	transferase activity, transferring glycosyl groups
HQN79_07955	COG3100	YcgL domain-containing protein
HQN79_07955	COG0561	phosphatase activity
HQN79_07960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQN79_08015	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HQN79_08020	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HQN79_08025	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HQN79_08030	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HQN79_08035	COG1674	ftsk spoiiie
HQN79_08045	COG0492	ferredoxin-NADP+ reductase activity
HQN79_08070	COG2201	protein-glutamate methylesterase activity
HQN79_08085	COG0835	chemotaxis
HQN79_08090	COG0745	RESPONSE REGULATOR receiver
HQN79_08100	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HQN79_08105	COG0835	chemotaxis
HQN79_08110	COG0643	Histidine kinase
HQN79_08110	COG0784	Response regulator, receiver
HQN79_08110	COG2198	Histidine kinase
HQN79_08115	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
HQN79_08140	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HQN79_08145	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
HQN79_08155	COG1987	bacterial-type flagellum assembly
HQN79_08185	COG1360	Flagellar Motor Protein
HQN79_08190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQN79_08220	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
HQN79_08230	COG1677	Flagellar hook-basal body complex protein FliE
HQN79_08255	COG1516	flagellar protein fliS
HQN79_08275	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HQN79_08280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HQN79_08290	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HQN79_08300	COG2089	acid synthase
HQN79_08310	COG1083	cytidylyl-transferase
HQN79_08315	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HQN79_08320	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HQN79_08320	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HQN79_08330	COG2089	acid synthase
HQN79_08345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HQN79_08350	COG0741	lytic transglycosylase activity
HQN79_08355	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HQN79_08370	COG1706	bacterial-type flagellum-dependent cell motility
HQN79_08380	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
HQN79_08385	COG4786	Flagellar basal body rod
HQN79_08390	COG4786	Flagellar basal body rod
HQN79_08400	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
HQN79_08410	COG1815	bacterial-type flagellum-dependent cell motility
HQN79_08420	COG0784	Response regulator, receiver
HQN79_08420	COG0835	chemotaxis
HQN79_08470	COG0308	aminopeptidase N
HQN79_08475	COG2885	chlorophyll binding
HQN79_08480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HQN79_08485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQN79_08495	COG0557	exoribonuclease II activity
HQN79_08510	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HQN79_08510	COG0301	tRNA thio-modification
HQN79_08515	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HQN79_08520	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HQN79_08525	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HQN79_08530	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HQN79_08540	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQN79_08545	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HQN79_08550	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HQN79_08555	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HQN79_08560	COG0617	tRNA 3'-terminal CCA addition
HQN79_08570	COG0180	Tryptophanyl-tRNA synthetase
HQN79_08575	COG0840	transmembrane signaling receptor activity
HQN79_08600	COG2205	protein histidine kinase activity
HQN79_08600	COG5002	protein histidine kinase activity
HQN79_08600	COG0784	Response regulator, receiver
HQN79_08605	COG5001	Diguanylate cyclase
HQN79_08605	COG5002	protein histidine kinase activity
HQN79_08615	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HQN79_08620	COG0732	type I restriction modification DNA specificity domain
HQN79_08635	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HQN79_08650	COG5377	YqaJ viral recombinase family
HQN79_08690	COG0582	viral genome integration into host DNA
HQN79_08700	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HQN79_08705	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HQN79_08715	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HQN79_08720	COG1546	Belongs to the CinA family
HQN79_08725	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HQN79_08730	COG3118	belongs to the thioredoxin family
HQN79_08745	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HQN79_08750	COG0488	(ABC) transporter
HQN79_08765	COG0326	Molecular chaperone. Has ATPase activity
HQN79_08780	COG2198	Histidine kinase
HQN79_08780	COG0643	Histidine kinase
HQN79_08785	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
HQN79_08795	COG0519	Catalyzes the synthesis of GMP from XMP
HQN79_08795	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HQN79_08820	COG0560	Phosphoserine phosphatase
HQN79_08830	COG0811	peptide transport
HQN79_08835	COG0848	biopolymer transport protein
HQN79_08840	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HQN79_08845	COG2166	iron-sulfur cluster assembly
HQN79_08860	COG0501	Belongs to the peptidase M48B family
HQN79_08865	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HQN79_08870	COG0154	amidase activity
HQN79_08875	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HQN79_08880	COG1077	Cell shape determining protein MreB Mrl
HQN79_08885	COG1792	Involved in formation and maintenance of cell shape
HQN79_08895	COG0768	penicillin binding
HQN79_08900	COG0772	Belongs to the SEDS family
HQN79_08905	COG1686	Belongs to the peptidase S11 family
HQN79_08910	COG2921	Belongs to the UPF0250 family
HQN79_08915	COG0321	lipoyl(octanoyl) transferase activity
HQN79_08920	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HQN79_08925	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HQN79_08930	COG3022	response to hydroperoxide
HQN79_08935	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HQN79_08940	COG2894	cell division
HQN79_08945	COG0850	regulation of cytokinetic process
HQN79_08955	COG1187	pseudouridine synthase activity
HQN79_08960	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HQN79_08970	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HQN79_08975	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HQN79_08980	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HQN79_08985	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HQN79_08990	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HQN79_09000	COG0271	Belongs to the BolA IbaG family
HQN79_09025	COG0306	phosphate transporter
HQN79_09040	COG0704	Plays a role in the regulation of phosphate uptake
HQN79_09045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HQN79_09060	COG0174	glutamine synthetase
HQN79_09065	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HQN79_09075	COG0347	Belongs to the P(II) protein family
HQN79_09080	COG0004	ammonium transporteR
HQN79_09095	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
HQN79_09100	COG0525	valine-tRNA ligase activity
HQN79_09105	COG4991	sh3 domain protein
HQN79_09115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HQN79_09125	COG0784	Response regulator, receiver
HQN79_09125	COG2205	protein histidine kinase activity
HQN79_09135	COG0335	large ribosomal subunit rRNA binding
HQN79_09140	COG0336	Belongs to the RNA methyltransferase TrmD family
HQN79_09145	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HQN79_09150	COG0228	four-way junction DNA binding
HQN79_09155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HQN79_09165	COG4536	flavin adenine dinucleotide binding
HQN79_09180	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HQN79_09185	COG0069	glutamate synthase activity
HQN79_09190	COG2857	Cytochrome c1
HQN79_09195	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HQN79_09200	COG0723	plastoquinol--plastocyanin reductase activity
HQN79_09205	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HQN79_09210	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HQN79_09215	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HQN79_09220	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HQN79_09230	COG0842	Transport permease protein
HQN79_09235	COG1131	(ABC) transporter
HQN79_09250	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HQN79_09255	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HQN79_09260	COG1127	ABC transporter
HQN79_09275	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HQN79_09290	COG1137	ATPase activity
HQN79_09300	COG2239	Acts as a magnesium transporter
HQN79_09310	COG0300	oxidoreductase activity
HQN79_09315	COG0277	FAD linked oxidase domain protein
HQN79_09325	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HQN79_09345	COG0489	protein tyrosine kinase activity
HQN79_09345	COG3206	protein involved in exopolysaccharide biosynthesis
HQN79_09365	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HQN79_09390	COG1086	Polysaccharide biosynthesis protein
HQN79_09405	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HQN79_09470	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HQN79_09475	COG0343	queuine tRNA-ribosyltransferase activity
HQN79_09485	COG1862	Preprotein translocase
HQN79_09490	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQN79_09495	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HQN79_09510	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HQN79_09525	COG2199	diguanylate cyclase activity
HQN79_09535	COG3021	interspecies interaction between organisms
HQN79_09540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HQN79_09550	COG4206	TonB-dependent receptor
HQN79_09550	COG4206	TonB-dependent receptor
HQN79_09565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HQN79_09570	COG1120	ATPase activity
HQN79_09595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HQN79_09605	COG3437	response regulator, receiver
HQN79_09610	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HQN79_09625	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HQN79_09630	COG0795	lipopolysaccharide-transporting ATPase activity
HQN79_09640	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HQN79_09675	COG0556	nucleotide-excision repair
HQN79_09680	COG0436	Aminotransferase
HQN79_09685	COG1793	dna ligase
HQN79_09715	COG0523	cobalamin synthesis protein
HQN79_09720	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HQN79_09725	COG0683	leucine binding
HQN79_09735	COG0559	Belongs to the binding-protein-dependent transport system permease family
HQN79_09770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HQN79_09780	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HQN79_09785	COG0830	nickel cation binding
HQN79_09790	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HQN79_09795	COG0804	urea catabolic process
HQN79_09800	COG0832	Belongs to the urease beta subunit family
HQN79_09810	COG0829	nickel cation binding
HQN79_09825	COG0494	nUDIX hydrolase
HQN79_09830	COG1011	Hydrolase
HQN79_09835	COG0500	methyltransferase
HQN79_09845	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HQN79_09850	COG3038	cytochrome b561
HQN79_09860	COG0745	RESPONSE REGULATOR receiver
HQN79_09865	COG2205	protein histidine kinase activity
HQN79_09885	COG0488	(ABC) transporter
HQN79_09890	COG0456	acetyltransferase
HQN79_09895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HQN79_09900	COG1917	Cupin 2, conserved barrel domain protein
HQN79_09905	COG0527	aspartate kinase activity
HQN79_09910	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HQN79_09945	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HQN79_09950	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HQN79_09955	COG1295	ribonuclease BN
HQN79_09970	COG0693	protein deglycase activity
HQN79_09975	COG0793	Belongs to the peptidase S41A family
HQN79_09980	COG0640	Transcriptional regulator
HQN79_10000	COG0058	SHG alpha-glucan phosphorylase activity
HQN79_10005	COG0297	glycogen (starch) synthase activity
HQN79_10010	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HQN79_10025	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HQN79_10030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HQN79_10030	COG0517	IMP dehydrogenase activity
HQN79_10035	COG1519	Transferase
HQN79_10050	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HQN79_10065	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HQN79_10070	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HQN79_10080	COG2226	methyltransferase
HQN79_10090	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HQN79_10110	COG1404	Belongs to the peptidase S8 family
HQN79_10140	COG2165	general secretion pathway protein
HQN79_10155	COG1459	type II secretion system
HQN79_10235	COG0582	viral genome integration into host DNA
HQN79_10260	COG0193	aminoacyl-tRNA hydrolase activity
HQN79_10265	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HQN79_10285	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HQN79_10290	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HQN79_10295	COG2890	protein-(glutamine-N5) methyltransferase activity
HQN79_10300	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HQN79_10310	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
HQN79_10325	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HQN79_10340	COG0840	transmembrane signaling receptor activity
HQN79_10340	COG0840	transmembrane signaling receptor activity
HQN79_10370	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HQN79_10400	COG0751	glycine-tRNA ligase activity
HQN79_10415	COG0739	heme binding
HQN79_10420	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HQN79_10435	COG1090	epimerase
HQN79_10445	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HQN79_10460	COG0701	Predicted permease
HQN79_10475	COG0579	oxidoreductase
HQN79_10480	COG0523	cobalamin synthesis protein
HQN79_10485	COG1469	GTP cyclohydrolase I activity
HQN79_10515	COG2827	Endonuclease containing a URI domain
HQN79_10525	COG0628	permease
HQN79_10530	COG1611	Belongs to the LOG family
HQN79_10535	COG0513	Belongs to the DEAD box helicase family
HQN79_10560	COG1765	OsmC-like protein
HQN79_10570	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HQN79_10575	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HQN79_10590	COG0134	indole-3-glycerol-phosphate synthase activity
HQN79_10600	COG1192	Involved in chromosome partitioning
HQN79_10620	COG3002	Belongs to the UPF0753 family
HQN79_10625	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HQN79_10630	COG0583	DNA-binding transcription factor activity
HQN79_10635	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HQN79_10640	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HQN79_10665	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HQN79_10670	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HQN79_10675	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HQN79_10710	COG2832	Protein of unknown function (DUF454)
HQN79_10720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HQN79_10725	COG0512	Glutamine amidotransferase of anthranilate synthase
HQN79_10735	COG0546	phosphoglycolate phosphatase activity
HQN79_10750	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HQN79_10755	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HQN79_10760	COG0288	reversible hydration of carbon dioxide
HQN79_10790	COG0583	DNA-binding transcription factor activity
HQN79_10795	COG0583	DNA-binding transcription factor activity
HQN79_10800	COG1850	ribulose-bisphosphate carboxylase activity
HQN79_10830	COG3437	response regulator, receiver
HQN79_10835	COG0840	transmembrane signaling receptor activity
HQN79_10840	COG0191	fructose-bisphosphate aldolase activity
HQN79_10850	COG0126	phosphoglycerate kinase activity
HQN79_10855	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HQN79_10860	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HQN79_10865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQN79_10880	COG0577	efflux transmembrane transporter activity
HQN79_10880	COG1136	(ABC) transporter
HQN79_10885	COG1136	(ABC) transporter
HQN79_10885	COG0577	efflux transmembrane transporter activity
HQN79_10910	COG0617	tRNA 3'-terminal CCA addition
HQN79_10920	COG3100	YcgL domain-containing protein
HQN79_10925	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HQN79_10935	COG1280	lysine exporter protein (LysE YggA)
HQN79_10990	COG1929	Belongs to the glycerate kinase type-1 family
HQN79_11000	COG1215	transferase activity, transferring glycosyl groups
HQN79_11020	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HQN79_11025	COG0585	pseudouridine synthase activity
HQN79_11060	COG2813	Specifically methylates the guanine in position
HQN79_11070	COG1454	alcohol dehydrogenase
HQN79_11085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HQN79_11095	COG1538	Outer membrane efflux protein
HQN79_11100	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HQN79_11105	COG0840	transmembrane signaling receptor activity
HQN79_11120	COG4771	TonB-dependent receptor
HQN79_11140	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HQN79_11145	COG0390	transport system, permease component
HQN79_11155	COG0210	DNA helicase
HQN79_11170	COG0254	rRNA binding
HQN79_11180	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HQN79_11185	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
HQN79_11190	COG1194	a g-specific adenine glycosylase
HQN79_11195	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HQN79_11210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HQN79_11215	COG2814	Major facilitator Superfamily
HQN79_11220	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HQN79_11230	COG1561	YicC-like family, N-terminal region
HQN79_11245	COG3001	Fructosamine kinase
HQN79_11250	COG0563	adenylate kinase activity
HQN79_11275	COG2205	protein histidine kinase activity
HQN79_11275	COG2770	Histidine kinase
HQN79_11290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQN79_11295	COG3437	response regulator, receiver
HQN79_11295	COG0784	Response regulator, receiver
HQN79_11300	COG3706	GGDEF domain
HQN79_11325	COG0189	ligase activity
HQN79_11350	COG1429	ligase activity, forming nitrogen-metal bonds
HQN79_11355	COG4771	TonB-dependent receptor
HQN79_11365	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HQN79_11370	COG1854	S-ribosylhomocysteine lyase activity
HQN79_11385	COG0259	pyridoxamine-phosphate oxidase activity
HQN79_11405	COG0667	Aldo Keto reductase
HQN79_11450	COG4999	Histidine kinase
HQN79_11450	COG3850	Histidine kinase
HQN79_11450	COG2205	protein histidine kinase activity
HQN79_11450	COG3437	response regulator, receiver
HQN79_11460	COG0347	Belongs to the P(II) protein family
HQN79_11465	COG0004	ammonium transporteR
HQN79_11475	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HQN79_11475	COG0519	Catalyzes the synthesis of GMP from XMP
HQN79_11480	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HQN79_11485	COG0069	glutamate synthase activity
HQN79_11490	COG2218	PFAM glutamate synthase alpha subunit domain protein
HQN79_11495	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HQN79_11510	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQN79_11510	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HQN79_11525	COG0788	formyltetrahydrofolate deformylase activity
HQN79_11530	COG3842	ATPase activity
HQN79_11535	COG4149	molybdate abc transporter
HQN79_11540	COG1840	ABC-type Fe3 transport system, periplasmic component
HQN79_11545	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
HQN79_11560	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HQN79_11580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HQN79_11585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HQN79_11590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HQN79_11590	COG1116	anion transmembrane transporter activity
HQN79_11595	COG3604	Transcriptional regulator
HQN79_11600	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HQN79_11605	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HQN79_11610	COG1116	anion transmembrane transporter activity
HQN79_11630	COG0469	pyruvate kinase activity
HQN79_11640	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HQN79_11660	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HQN79_11665	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HQN79_11680	COG0676	glucose-6-phosphate 1-epimerase activity
HQN79_11685	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HQN79_11690	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HQN79_11695	COG0194	GDP metabolic process
HQN79_11700	COG1758	RNA polymerase activity
HQN79_11705	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HQN79_11740	COG1528	Iron-storage protein
HQN79_11760	COG3161	chorismate lyase activity
HQN79_11775	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HQN79_11785	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HQN79_11790	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HQN79_11795	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HQN79_11805	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HQN79_11810	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HQN79_11815	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HQN79_11820	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HQN79_11825	COG0356	it plays a direct role in the translocation of protons across the membrane
HQN79_11845	COG1192	Involved in chromosome partitioning
HQN79_11855	COG0445	tRNA wobble uridine modification
HQN79_11875	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HQN79_11880	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HQN79_11880	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HQN79_11925	COG1739	Uncharacterized protein family UPF0029
HQN79_11930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HQN79_11945	COG2095	MarC family integral membrane protein
HQN79_11955	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HQN79_11965	COG0706	membrane insertase activity
HQN79_11970	COG0594	ribonuclease P activity
HQN79_11975	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HQN79_11985	COG0730	response to heat