locus-tag	class	description
THIAE_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
THIAE_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
THIAE_00020	ENOG4107S7U	Sulfide dehydrogenase
THIAE_00025	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
THIAE_00030	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
THIAE_00035	ENOG4105M00	molybdopterin converting factor, subunit 1
THIAE_00040	ENOG4108ZAF	Molybdopterin
THIAE_00045	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
THIAE_00050	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
THIAE_00060	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
THIAE_00065	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
THIAE_00070	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
THIAE_00090	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THIAE_00100	ENOG4105BZU	Histidine kinase
THIAE_00110	ENOG4105CGY	Dna recombination protein
THIAE_00115	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THIAE_00120	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THIAE_00125	ENOG4105BZU	Histidine kinase
THIAE_00145	ENOG4105WH1	Two component transcriptional regulator luxr family
THIAE_00150	ENOG4107QZV	Type I secretion membrane fusion protein
THIAE_00160	ENOG4105CDV	Ompa motb domain protein
THIAE_00180	ENOG4105C87	Aminotransferase class I and II
THIAE_00185	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
THIAE_00190	ENOG4105C8Q	Methyl-accepting chemotaxis
THIAE_00195	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
THIAE_00200	ENOG4108JQC	penicillin-binding protein 1A
THIAE_00210	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
THIAE_00215	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
THIAE_00220	ENOG4105CSA	Coproporphyrinogen iii oxidase
THIAE_00230	ENOG4105C1J	atp-dependent rna helicase
THIAE_00270	ENOG4105CUC	YeeE YedE family protein
THIAE_00275	ENOG4105CHH	sulfate transporter
THIAE_00305	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
THIAE_00310	ENOG4105CB5	ATP-dependent DNA helicase recG
THIAE_00315	ENOG4105KME	endoribonuclease L-psp
THIAE_00320	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
THIAE_00325	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
THIAE_00330	ENOG4105D64	Mechanosensitive ion channel
THIAE_00335	ENOG4108Z0R	Transferase
THIAE_00340	ENOG4105E2X	shikimate dehydrogenase
THIAE_00345	ENOG4105D52	delta-aminolevulinic acid dehydratase
THIAE_00350	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
THIAE_00360	ENOG4105CUV	Homoserine Kinase
THIAE_00370	ENOG4105E9K	Isocitrate dehydrogenase
THIAE_00380	ENOG4108EX3	reductase
THIAE_00385	ENOG4105CGK	Exodeoxyribonuclease III
THIAE_00390	ENOG4105CIY	formyltetrahydrofolate deformylase
THIAE_00395	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
THIAE_00400	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
THIAE_00425	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
THIAE_00440	ENOG4105CBX	hi0933 family
THIAE_00450	ENOG4105KCK	Peptidoglycan-associated lipoprotein
THIAE_00455	ENOG4105EHV	domain protein
THIAE_00465	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
THIAE_00470	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
THIAE_00475	ENOG4107RJC	Iron-containing alcohol dehydrogenase
THIAE_00480	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
THIAE_00485	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
THIAE_00490	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
THIAE_00495	ENOG4105D49	3-dehydroquinate synthase
THIAE_00500	ENOG4105DSB	aldose 1-epimerase
THIAE_00515	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
THIAE_00520	ENOG4105VNG	YcgL domain-containing protein
THIAE_00525	ENOG4105CGD	Nad-dependent epimerase dehydratase
THIAE_00530	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
THIAE_00550	ENOG4105CV1	Transketolase (EC 2.2.1.1)
THIAE_00555	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
THIAE_00560	ENOG4105BZA	Phosphoglycerate kinase
THIAE_00565	ENOG4105CA9	Pyruvate kinase
THIAE_00570	ENOG4105D2N	Aldolase
THIAE_00575	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
THIAE_00595	ENOG4108IQK	o-acetylhomoserine
THIAE_00600	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
THIAE_00605	ENOG4105C8V	SAICAR synthetase
THIAE_00615	ENOG4105DJV	ribulose-phosphate 3-epimerase
THIAE_00620	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
THIAE_00625	ENOG4105CRQ	synthase (Component I)
THIAE_00630	ENOG4105DDQ	anthranilate synthase
THIAE_00635	ENOG4107QYG	anthranilate phosphoribosyltransferase
THIAE_00640	ENOG4105DK0	Indole-3-glycerol phosphate synthase
THIAE_00645	ENOG4108UKZ	OsmC family
THIAE_00650	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
THIAE_00655	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
THIAE_00660	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
THIAE_00680	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
THIAE_00690	ENOG4105PM1	preprotein translocase subunit SecE
THIAE_00695	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
THIAE_00700	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
THIAE_00705	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
THIAE_00710	ENOG4108VZM	50s ribosomal protein L10
THIAE_00715	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
THIAE_00720	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
THIAE_00725	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
THIAE_00730	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
THIAE_00735	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
THIAE_00740	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
THIAE_00745	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
THIAE_00750	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
THIAE_00755	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
THIAE_00760	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
THIAE_00765	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
THIAE_00770	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
THIAE_00775	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
THIAE_00780	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
THIAE_00785	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
THIAE_00790	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
THIAE_00795	ENOG41083MP	50s ribosomal protein l29
THIAE_00800	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
THIAE_00805	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
THIAE_00810	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
THIAE_00815	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
THIAE_00820	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
THIAE_00825	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
THIAE_00830	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
THIAE_00835	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
THIAE_00840	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
THIAE_00845	ENOG4105VPB	50S ribosomal protein L30
THIAE_00850	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
THIAE_00855	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
THIAE_00860	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
THIAE_00865	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
THIAE_00870	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
THIAE_00875	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
THIAE_00880	ENOG4108ZT0	50S ribosomal protein l17
THIAE_00885	ENOG4105F8V	Hydrolase, tatD family
THIAE_00890	ENOG4105CUZ	uba thif-type nad fad binding protein
THIAE_00900	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
THIAE_00920	ENOG4108JUA	Transcriptional regulator
THIAE_00925	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
THIAE_00940	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
THIAE_00950	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
THIAE_00970	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
THIAE_00980	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
THIAE_00990	ENOG4107RDB	Major Facilitator
THIAE_00995	ENOG4108UUM	single-stranded DNA-binding protein
THIAE_01005	ENOG4105EAH	synthase
THIAE_01010	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
THIAE_01015	ENOG4105K46	50S ribosomal protein l27
THIAE_01020	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
THIAE_01025	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
THIAE_01030	ENOG4108ISG	Major Facilitator
THIAE_01040	ENOG4105C94	Transporter
THIAE_01045	ENOG4108M8H	domain protein
THIAE_01050	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
THIAE_01055	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
THIAE_01060	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
THIAE_01065	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
THIAE_01070	ENOG4105BZN	citrate synthase
THIAE_01075	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
THIAE_01080	ENOG4108UJD	30S ribosomal protein S9
THIAE_01085	ENOG4105BZU	Histidine kinase
THIAE_01090	ENOG4108XDN	Transcriptional regulator
THIAE_01095	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
THIAE_01110	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
THIAE_01125	ENOG4107FW0	short-chain dehydrogenase reductase
THIAE_01140	ENOG4105FAV	ABC, transporter
THIAE_01145	ENOG4105FDK	ABC transporter
THIAE_01160	ENOG4105DIW	FeS assembly protein SUFB
THIAE_01165	ENOG4105C3K	feS assembly ATPase SufC
THIAE_01170	ENOG4105JRK	feS assembly protein SufD
THIAE_01180	ENOG4105DFU	Cell wall formation (By similarity)
THIAE_01185	ENOG4105CPF	Cell wall formation (By similarity)
THIAE_01190	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
THIAE_01195	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
THIAE_01200	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
THIAE_01210	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
THIAE_01215	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
THIAE_01220	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
THIAE_01225	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
THIAE_01235	ENOG4105CAQ	asparagine synthetase
THIAE_01240	ENOG4105M2J	Glutaredoxin
THIAE_01245	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
THIAE_01250	ENOG4107QZM	n-acetylglutamate synthase
THIAE_01255	ENOG4105C01	Dihydroxy-acid dehydratase
THIAE_01265	ENOG41088H4	Diheme cytochrome SoxA (Sulfur oxidation)
THIAE_01285	ENOG4105ERG	peptidase m48, ste24p
THIAE_01290	ENOG4105VFE	sira family
THIAE_01295	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
THIAE_01300	ENOG4107QP8	phosphohexose isomerase
THIAE_01305	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
THIAE_01310	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
THIAE_01315	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
THIAE_01325	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
THIAE_01330	ENOG4105ECY	inositol monophosphatase
THIAE_01345	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
THIAE_01350	ENOG4108Z4V	iron-sulfur cluster assembly
THIAE_01355	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
THIAE_01360	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
THIAE_01370	ENOG4105CUT	histidyl-tRNA synthetase
THIAE_01380	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
THIAE_01385	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
THIAE_01390	ENOG4105CQB	FAD linked oxidase domain protein
THIAE_01395	ENOG4106RE7	Cytochrome
THIAE_01410	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
THIAE_01415	ENOG41090A4	Pterin carbinolamine dehydratase
THIAE_01420	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
THIAE_01425	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
THIAE_01430	ENOG4105C7K	acetolactate synthase
THIAE_01435	ENOG4108ZP8	Acetolactate synthase small subunit
THIAE_01440	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
THIAE_01445	ENOG4105BZ8	glutamate synthase
THIAE_01450	ENOG4105CBC	glutamate synthase
THIAE_01455	ENOG4107R37	Glutamate dehydrogenase
THIAE_01460	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
THIAE_01465	ENOG41082J7	Rhodanese domain protein
THIAE_01470	ENOG4105VW4	glutaredoxin 3
THIAE_01475	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
THIAE_01480	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
THIAE_01485	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
THIAE_01490	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
THIAE_01495	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
THIAE_01525	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
THIAE_01530	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
THIAE_01540	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
THIAE_01560	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
THIAE_01575	ENOG4106H78	methyltransferase
THIAE_01580	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
THIAE_01595	ENOG4108VPT	UPF0234 protein
THIAE_01600	ENOG4105CAS	nag kinase
THIAE_01615	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
THIAE_01625	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
THIAE_01630	ENOG4105C9X	ppx gppa phosphatase
THIAE_01640	ENOG4105DSF	transport protein
THIAE_01645	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
THIAE_01660	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
THIAE_01670	ENOG410642E	Short chain dehydrogenase
THIAE_01675	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
THIAE_01680	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
THIAE_01695	ENOG4105CD3	dihydroorotase
THIAE_01700	ENOG4105DZR	Type I site-specific deoxyribonuclease
THIAE_01705	ENOG4105K4U	addiction module toxin, RelE StbE family
THIAE_01720	ENOG4105EKX	Restriction modification system DNA (Specificity
THIAE_01730	ENOG4105CB5	ATP-dependent DNA helicase recG
THIAE_01735	ENOG4105CVR	type I restriction-modification system
THIAE_01740	ENOG4105DFA	alanine racemase domain protein
THIAE_01745	ENOG4105CSR	polyphosphate kinase 2
THIAE_01755	ENOG4105C8Q	Methyl-accepting chemotaxis
THIAE_01765	ENOG4105CD3	dihydroorotase
THIAE_01770	ENOG4105CXT	aspartate transcarbamylase
THIAE_01775	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
THIAE_01780	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
THIAE_01785	ENOG4108UJU	UPF0301 protein
THIAE_01790	ENOG4105CJ2	(LipO)protein
THIAE_01795	ENOG4105D7Z	glutathione synthase
THIAE_01815	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
THIAE_01820	ENOG4105W0E	50S ribosomal protein L33
THIAE_01825	ENOG4105KDC	50s ribosomal protein l28
THIAE_01830	ENOG4105W5Q	DNA repair protein (RadC
THIAE_01845	ENOG4105DWV	Homoserine O-trans-acetylase
THIAE_01850	ENOG4105DWV	Homoserine O-trans-acetylase
THIAE_01855	ENOG4108VIA	integral membrane protein
THIAE_01860	ENOG4105II7	pyrroline-5-carboxylate reductase
THIAE_01865	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
THIAE_01875	ENOG4105C8Q	Methyl-accepting chemotaxis
THIAE_01880	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
THIAE_01885	ENOG4105CKI	cobalamin synthesis protein
THIAE_01890	ENOG4107RSR	Malate quinone oxidoreductase
THIAE_01900	ENOG4105CPC	Aldo Keto reductase
THIAE_01910	ENOG4107QX9	Thiol disulfide interChange protein
THIAE_01930	ENOG4105CD8	aminopeptidase N
THIAE_01965	ENOG4105DFU	Cell wall formation (By similarity)
THIAE_01975	ENOG4105D05	Receptor
THIAE_01980	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
THIAE_01990	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
THIAE_02010	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
THIAE_02015	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
THIAE_02020	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
THIAE_02025	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
THIAE_02035	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
THIAE_02040	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
THIAE_02055	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
THIAE_02060	ENOG4105BZU	Histidine kinase
THIAE_02070	ENOG4108GAE	asmA family
THIAE_02075	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
THIAE_02090	ENOG4105BZU	Histidine kinase
THIAE_02100	ENOG4105CQB	FAD linked oxidase domain protein
THIAE_02105	ENOG4108JQ1	Dehydrogenase
THIAE_02110	ENOG4105DWF	phosphomethylpyrimidine kinase
THIAE_02115	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
THIAE_02160	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
THIAE_02160	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
THIAE_02165	ENOG4108MGY	Histidine kinase
THIAE_02175	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THIAE_02185	ENOG4105CUY	Mechanosensitive ion channel
THIAE_02190	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
THIAE_02195	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
THIAE_02200	ENOG4105C9A	Phoh family
THIAE_02205	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
THIAE_02210	ENOG4108JU5	Magnesium and cobalt efflux protein
THIAE_02215	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
THIAE_02220	ENOG4105C5F	glutamine synthetase
THIAE_02225	ENOG4105C8U	phosphate abc transporter
THIAE_02230	ENOG4105E2Z	phosphate ABC transporter (Permease
THIAE_02235	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
THIAE_02240	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
THIAE_02245	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
THIAE_02250	ENOG4105BZU	Histidine kinase
THIAE_02270	ENOG4105C8Q	Methyl-accepting chemotaxis
THIAE_02300	ENOG410811Q	Ferredoxin
THIAE_02305	ENOG4105M85	Bola protein
THIAE_02320	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
THIAE_02325	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
THIAE_02330	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
THIAE_02335	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
THIAE_02335	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
THIAE_02340	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
THIAE_02345	ENOG4105EHM	Aminoglycoside phosphotransferase
THIAE_02350	ENOG4108S0S	Nucleotidyl transferase
THIAE_02360	ENOG4105D1Q	UPF0246 protein
THIAE_02365	ENOG4105BZU	Histidine kinase
THIAE_02370	ENOG4105BZU	Histidine kinase
THIAE_02390	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
THIAE_02395	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
THIAE_02400	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
THIAE_02405	ENOG4108Z43	UPF0250 protein
THIAE_02410	ENOG4105F0I	Aminotransferase
THIAE_02415	ENOG4105DZ1	carboxypeptidase
THIAE_02420	ENOG4105CNI	cell division protein FtsW
THIAE_02425	ENOG4105CJN	penicillin-binding protein
THIAE_02435	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
THIAE_02440	ENOG4105DFF	Rod shape-determining protein mreb
THIAE_02445	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
THIAE_02450	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
THIAE_02455	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
THIAE_02460	ENOG4105D0M	Protease HtpX homolog
THIAE_02465	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
THIAE_02470	ENOG4105DJ0	Poly(A) Polymerase
THIAE_02475	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
THIAE_02480	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
THIAE_02485	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
THIAE_02490	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
THIAE_02495	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
THIAE_02500	ENOG4105F0N	pyrophosphate phospho-hydrolase
THIAE_02505	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
THIAE_02510	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
THIAE_02515	ENOG4107QN2	dihydrolipoyl dehydrogenase
THIAE_02520	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
THIAE_02525	ENOG4105C2N	RNA methyltransferase TrmH family group 3
THIAE_02530	ENOG4108KPW	sugar kinase
THIAE_02535	ENOG4105CJ3	phosphate transporter
THIAE_02540	ENOG4105D6S	protein involved in catabolism of external DNA
THIAE_02565	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THIAE_02570	ENOG4108JPZ	Monovalent cation H antiporter subunit D
THIAE_02575	ENOG4108JPZ	Monovalent cation H antiporter subunit D
THIAE_02580	ENOG4108F3G	Type I restriction-modification system, R subunit
THIAE_02585	ENOG4105DFS	Conserved Protein
THIAE_02595	ENOG4105CVR	type I restriction-modification system
THIAE_02650	ENOG4107TPS	domain protein
THIAE_02665	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
THIAE_02695	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THIAE_02700	ENOG4108JPZ	Monovalent cation H antiporter subunit D
THIAE_02715	ENOG4107QX8	SPFH domain, Band 7 family protein
THIAE_02740	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
THIAE_02740	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
THIAE_02745	ENOG4105BZU	Histidine kinase
THIAE_02750	ENOG4105C8Q	Methyl-accepting chemotaxis
THIAE_02760	ENOG4105BZU	Histidine kinase
THIAE_02775	ENOG4105BZU	Histidine kinase
THIAE_02780	ENOG4105BZU	Histidine kinase
THIAE_02815	ENOG4107S7U	Sulfide dehydrogenase
THIAE_02840	ENOG4105CD3	dihydroorotase
THIAE_02845	ENOG4105DUM	transcriptional regulator, lysR family
THIAE_02875	ENOG4105EMN	RNA polymerase sigma factor
THIAE_02880	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
THIAE_02885	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
THIAE_02895	ENOG4105BZU	Histidine kinase
THIAE_02910	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
THIAE_02915	ENOG4105DR5	peptidase
THIAE_02920	ENOG4105VFE	sira family
THIAE_02925	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
THIAE_02930	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
THIAE_02935	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
THIAE_02945	ENOG4105E14	MotA TolQ exbB proton channel
THIAE_02955	ENOG4106VK6	Flagellar motor protein
THIAE_02960	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
THIAE_02970	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
THIAE_02985	ENOG4105CJR	Integral membrane protein (MviN
THIAE_02990	ENOG4105DTN	riboflavin biosynthesis protein ribF
THIAE_02995	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
THIAE_03000	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
THIAE_03005	ENOG410620I	Diguanylate cyclase
THIAE_03020	ENOG4105CVE	Lytic murein transglycosylase
THIAE_03025	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
THIAE_03030	ENOG4105BZU	Histidine kinase
THIAE_03035	ENOG4105D4P	Coproporphyrinogen iii oxidase
THIAE_03045	ENOG4107QHF	type ii secretion system protein e
THIAE_03050	ENOG4105D7Q	type ii secretion system
THIAE_03070	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
THIAE_03095	ENOG4107RAQ	aminopeptidase
THIAE_03100	ENOG4105D0A	hydroxylase
THIAE_03105	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
THIAE_03125	ENOG4105C03	ribonuclease
THIAE_03130	ENOG4105EI2	Pseudouridine synthase
THIAE_03135	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
THIAE_03140	ENOG4108UHJ	MAF-like protein
THIAE_03145	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
THIAE_03150	ENOG4105VGS	50s ribosomal protein l32
THIAE_03155	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
THIAE_03160	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
THIAE_03165	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
THIAE_03170	ENOG4105CHR	reductase
THIAE_03175	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
THIAE_03180	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
THIAE_03195	ENOG4105HHA	aminodeoxychorismate lyase
THIAE_03200	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
THIAE_03205	ENOG4107QRG	dna polymerase iii
THIAE_03210	ENOG4105F8V	Hydrolase, tatD family
THIAE_03215	ENOG4105BZ1	(ABC) transporter
THIAE_03240	ENOG4108YZY	peptidylprolyl cis-trans isomerase
THIAE_03250	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
THIAE_03255	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
THIAE_03260	ENOG4105C4K	Nad synthetase
THIAE_03275	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
THIAE_03280	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
THIAE_03290	ENOG4105C8J	)-transporter
THIAE_03305	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
THIAE_03310	ENOG4105KUZ	arsenate reductase
THIAE_03315	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
THIAE_03330	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
THIAE_03345	ENOG4105CFP	Peptidase U32
THIAE_03350	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
THIAE_03355	ENOG4108K3A	Glutathione S-transferase
THIAE_03360	ENOG41075W9	High frequency lysogenization protein HflD homolog
THIAE_03365	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
THIAE_03370	ENOG4108R99	pseudouridine synthase
THIAE_03380	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
THIAE_03385	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
THIAE_03395	ENOG4105K6H	D-cysteine desulfhydrase
THIAE_03400	ENOG4105DAN	ATP-dependent protease
THIAE_03410	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
THIAE_03440	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
THIAE_03445	ENOG4105W49	UPF0434 protein
THIAE_03450	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
THIAE_03460	ENOG4105IPS	esterase
THIAE_03465	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
THIAE_03470	ENOG4107QMS	site-determining protein
THIAE_03475	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
THIAE_03485	ENOG4108JA2	transcriptioN-repair coupling factor
THIAE_03490	ENOG4105EN6	Membrane
THIAE_03500	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
THIAE_03505	ENOG4105C5H	ABC transporter
THIAE_03520	ENOG4105BZU	Histidine kinase
THIAE_03525	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
THIAE_03530	ENOG4105C8Q	Methyl-accepting chemotaxis
THIAE_03535	ENOG4105C1J	atp-dependent rna helicase
THIAE_03565	ENOG4105C7B	Threonine dehydratase
THIAE_03570	ENOG4105CV6	ABC transporter, permease
THIAE_03575	ENOG4108I0Y	(ABC) transporter
THIAE_03580	ENOG4108UJV	acyl-CoA thioesterase i
THIAE_03585	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
THIAE_03590	ENOG4108Z1B	Cyclase dehydrase
THIAE_03595	ENOG4105VDB	UPF0125 protein
THIAE_03600	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
THIAE_03605	ENOG41090R7	Ferric uptake
THIAE_03610	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
THIAE_03615	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
THIAE_03620	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
THIAE_03625	ENOG4105CFG	Acts as a chaperone (By similarity)
THIAE_03630	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
THIAE_03635	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
THIAE_03640	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
THIAE_03645	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
THIAE_03650	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
THIAE_03660	ENOG4105ED9	Protein of unknown function (DUF455)
THIAE_03665	ENOG4105DKQ	ROK family
THIAE_03675	ENOG41080RH	Thioredoxin
THIAE_03685	ENOG4105WH1	Two component transcriptional regulator luxr family
THIAE_03695	ENOG4105BZU	Histidine kinase
THIAE_03700	ENOG4105C5H	ABC transporter
THIAE_03705	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
THIAE_03710	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
THIAE_03715	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
THIAE_03730	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
THIAE_03735	ENOG4107YIM	Involved in the transcription termination process (By similarity)
THIAE_03740	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
THIAE_03745	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
THIAE_03755	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
THIAE_03760	ENOG4107XVI	synthase
THIAE_03765	ENOG4105CTB	Polyprenyl synthetase
THIAE_03770	ENOG4105E1F	short-chain dehydrogenase reductase
THIAE_03780	ENOG4105C9M	aspartyl-trna synthetase
THIAE_03785	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
THIAE_03790	ENOG4105CDY	transcriptional regulatory protein
THIAE_03795	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
THIAE_03800	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
THIAE_03805	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
THIAE_03810	ENOG4105E02	MotA TolQ exbB proton channel
THIAE_03815	ENOG4105M8F	Biopolymer transport protein exbD tolR
THIAE_03825	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
THIAE_03830	ENOG4105KCK	Peptidoglycan-associated lipoprotein
THIAE_03840	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
THIAE_03860	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
THIAE_03865	ENOG4108V3W	Chemotaxis protein, CheW
THIAE_03870	ENOG4105CNG	UPF0061 protein
THIAE_03880	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
THIAE_03885	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
THIAE_03890	ENOG4108ZC9	flagellar basal-body rod protein flgc
THIAE_03900	ENOG4105BZE	flagellar hook protein, FlgE
THIAE_03910	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
THIAE_03915	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
THIAE_03920	ENOG4105VIE	preprotein translocase, subunit YajC
THIAE_03925	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
THIAE_03930	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
THIAE_03935	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
THIAE_03945	ENOG4105C3M	thioredoxin reductase
THIAE_03950	ENOG4105CNU	cell division protein FtsK
THIAE_03955	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
THIAE_03960	ENOG4105D1H	recombination factor protein RarA
THIAE_03965	ENOG4105WMR	Protein CrcB homolog
THIAE_03970	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
THIAE_03980	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
THIAE_04005	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
THIAE_04010	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
THIAE_04015	ENOG4105CE9	30S ribosomal protein S2
THIAE_04020	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
THIAE_04025	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
THIAE_04030	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
THIAE_04035	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
THIAE_04040	ENOG4105KNE	Phosphatidate cytidylyltransferase
THIAE_04045	ENOG4105DZP	Membrane-associated zinc metalloprotease
THIAE_04050	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
THIAE_04055	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
THIAE_04060	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
THIAE_04065	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
THIAE_04070	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
THIAE_04075	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
THIAE_04080	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
THIAE_04085	ENOG4107R88	Chemotaxis protein (CheV)
THIAE_04090	ENOG4105YK5	50S ribosomal protein L36
THIAE_04095	ENOG4105DVT	helicase
THIAE_04100	ENOG41072GX	Peptidase M22 Glycoprotease
THIAE_04105	ENOG41081QV	Universal stress protein
THIAE_04120	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
THIAE_04130	ENOG4105BZ1	(ABC) transporter
THIAE_04145	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
THIAE_04160	ENOG4105D16	lipopolysaccharide heptosyltransferase i
THIAE_04175	ENOG4105D16	lipopolysaccharide heptosyltransferase i
THIAE_04240	ENOG4105CB5	ATP-dependent DNA helicase recG
THIAE_04245	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
THIAE_04255	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
THIAE_04310	ENOG4105CMM	transposase
THIAE_04370	ENOG4105CG5	Glycosyl transferase (Group 1
THIAE_04390	ENOG4105CMR	udp-glucose 4-epimerase
THIAE_04455	ENOG4105BZU	Histidine kinase
THIAE_04460	ENOG4108IYU	L-aspartate oxidase
THIAE_04470	ENOG4105C0H	protease
THIAE_04475	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
THIAE_04480	ENOG4105C3F	Signal peptidase i
THIAE_04500	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
THIAE_04505	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
THIAE_04510	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
THIAE_04520	ENOG4105E33	succinate dehydrogenase
THIAE_04525	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
THIAE_04540	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
THIAE_04545	ENOG4105C0B	DNA polymerase III (alpha subunit)
THIAE_04550	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
THIAE_04565	ENOG4107QN1	sodium solute
THIAE_04580	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
THIAE_04585	ENOG4105CHV	Transcription elongation factor NusA
THIAE_04590	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
THIAE_04595	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
THIAE_04600	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
THIAE_04605	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
THIAE_04615	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
THIAE_04620	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
THIAE_04630	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
THIAE_04645	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
THIAE_04690	ENOG4105VRT	cytoplasmic protein
THIAE_04730	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
THIAE_04740	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
THIAE_04760	ENOG4108IAB	Phoh family
THIAE_04765	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THIAE_04770	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
THIAE_04780	ENOG4108ETH	Formylglycinamide ribotide synthetase
THIAE_04790	ENOG4105CHH	sulfate transporter
THIAE_04805	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
THIAE_04810	ENOG4105CRK	lysyL-tRNA synthetase
THIAE_04815	ENOG4105BZM	domain protein
THIAE_04850	ENOG4108R85	Short chain dehydrogenase
THIAE_04855	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
THIAE_04860	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
THIAE_04865	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
THIAE_04870	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
THIAE_04875	ENOG4105CQC	Prephenate dehydratase
THIAE_04880	ENOG4105CIH	Imidazole acetol-phosphate transaminase
THIAE_04885	ENOG4105EVN	Prephenate dehydrogenase
THIAE_04890	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
THIAE_04895	ENOG4105CAT	Cytidine monophosphate kinase
THIAE_04900	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
THIAE_04905	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
THIAE_04915	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
THIAE_04920	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
THIAE_04925	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
THIAE_04935	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
THIAE_04940	ENOG4105CDU	Replicative dna helicase
THIAE_04945	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
THIAE_04950	ENOG4107VIJ	nudix hydrolase
THIAE_04980	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THIAE_04990	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THIAE_05005	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
THIAE_05005	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
THIAE_05010	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
THIAE_05025	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
THIAE_05030	ENOG4108KMM	Diguanylate cyclase
THIAE_05035	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
THIAE_05040	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
THIAE_05050	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
THIAE_05065	ENOG4107QZF	nitrite reductase NADPH large subunit
THIAE_05070	ENOG4108IFG	nitrite reductase, (NAD(P)H)
THIAE_05075	ENOG4105D7T	ABC transporter
THIAE_05095	ENOG4105EYH	Exonuclease
THIAE_05100	ENOG4107RFY	SbcCD D subunit
THIAE_05120	ENOG4105K5B	UPF0225 protein
THIAE_05125	ENOG4105MZG	transcriptional modulator of maze toxin, mazf
THIAE_05165	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
THIAE_05170	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
THIAE_05175	ENOG4105KQ5	peptidylprolyl cis-trans isomerase
THIAE_05180	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
THIAE_05190	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
THIAE_05200	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
THIAE_05235	ENOG41080ZE	Adenylate cyclase
THIAE_05245	ENOG4105C6T	cysteine synthase
THIAE_05260	ENOG4105FE9	pseudouridine synthase
THIAE_05265	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
THIAE_05270	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
THIAE_05275	ENOG4108Z4T	Peptidase M50
THIAE_05280	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
THIAE_05285	ENOG4105DB7	PHP domain protein
THIAE_05290	ENOG4107835	probably involved in intracellular septation (By similarity)
THIAE_05295	ENOG4105K9H	YciI-like protein
THIAE_05300	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
THIAE_05320	ENOG4105N42	UPF0307 protein
THIAE_05325	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
THIAE_05335	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
THIAE_05340	ENOG4107S5T	Carbohydrate kinase
THIAE_05350	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
THIAE_05355	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
THIAE_05360	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
THIAE_05365	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
THIAE_05375	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
THIAE_05380	ENOG4107QID	Threonine synthase
THIAE_05390	ENOG4105D6E	homoserine dehydrogenase
THIAE_05395	ENOG4105CHM	Aminotransferase
THIAE_05405	ENOG4108K5P	(LipO)protein
THIAE_05410	ENOG4108UM1	dedA family
THIAE_05415	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
THIAE_05425	ENOG4108DG9	Smr protein MutS2
THIAE_05430	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
THIAE_05435	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
THIAE_05440	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
THIAE_05445	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
THIAE_05450	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
THIAE_05455	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
THIAE_05465	ENOG4105DDY	UPF0142 protein ycaO
THIAE_05480	ENOG4108W1A	pseudouridine synthase
THIAE_05490	ENOG4107QN2	dihydrolipoyl dehydrogenase
THIAE_05495	ENOG4107QSN	dihydrolipoamide acetyltransferase
THIAE_05500	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
THIAE_05505	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
THIAE_05515	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
THIAE_05525	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
THIAE_05530	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
THIAE_05535	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
THIAE_05540	ENOG4105C34	Pseudouridine synthase
THIAE_05555	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
THIAE_05565	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
THIAE_05570	ENOG4105E9H	Lytic Murein transglycosylase
THIAE_05575	ENOG4107SC1	transglycosylase
THIAE_05580	ENOG4105C8N	cysteinyl-tRNA synthetase
THIAE_05585	ENOG4105CX6	glutaminyL-tRNA synthetase
THIAE_05595	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
THIAE_05600	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
THIAE_05605	ENOG4105CK2	sodium dicarboxylate symporter
THIAE_05615	ENOG4108ZAI	phosphatidylglycerophosphatase a
THIAE_05620	ENOG4105CDH	Citrulline--aspartate ligase
THIAE_05625	ENOG4105DJ4	phosphatidylserine decarboxylase
THIAE_05630	ENOG4108YZA	Nitrogen regulatory protein pii
THIAE_05635	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THIAE_05640	ENOG4105CUX	Signal transduction histidine kinase
THIAE_05650	ENOG4105DSE	periplasmic solute binding protein
THIAE_05655	ENOG4105DIK	(ABC) transporter
THIAE_05660	ENOG4105CC5	ABC transporter
THIAE_05665	ENOG4105CC5	ABC transporter
THIAE_05680	ENOG4107QTF	adenylosuccinate lyase
THIAE_05685	ENOG4105EZE	Cupin 4 family protein
THIAE_05695	ENOG4105BZU	Histidine kinase
THIAE_05700	ENOG4105BZU	Histidine kinase
THIAE_05725	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
THIAE_05730	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
THIAE_05735	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
THIAE_05740	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
THIAE_05745	ENOG4105M08	Membrane
THIAE_05840	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
THIAE_05850	ENOG4105CMM	transposase
THIAE_05865	ENOG4105CFI	type iii restriction protein res subunit
THIAE_05895	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
THIAE_05925	ENOG4105C5H	ABC transporter
THIAE_05930	ENOG4108YXA	Membrane
THIAE_05935	ENOG4108YZY	peptidylprolyl cis-trans isomerase
THIAE_05945	ENOG4107QKV	phosphomannomutase
THIAE_06055	ENOG4105W5Q	DNA repair protein (RadC
THIAE_06200	ENOG4108C33	Resolvase
THIAE_06205	ENOG410645W	Thiamin biosynthesis protein ThiH
THIAE_06230	ENOG4108ZXE	
THIAE_06285	ENOG4108KU3	Integrase
THIAE_06300	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THIAE_06305	ENOG4105C8S	subunit m
THIAE_06310	ENOG4105D65	subunit l
THIAE_06315	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THIAE_06320	ENOG4105DF2	NADH dehydrogenase subunit j
THIAE_06325	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THIAE_06330	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
THIAE_06335	ENOG4108IEH	NADH dehydrogenase subunit g
THIAE_06340	ENOG4107QIZ	NADH dehydrogenase
THIAE_06350	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THIAE_06355	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
THIAE_06360	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THIAE_06365	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
THIAE_06375	ENOG4107EJC	Preprotein translocase subunit SecG
THIAE_06380	ENOG4105CP7	Triose-phosphate isomerase
THIAE_06385	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
THIAE_06390	ENOG4105EEI	dihydropteroate synthase
THIAE_06395	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
THIAE_06400	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
THIAE_06405	ENOG4105HBR	Rna-binding protein
THIAE_06410	ENOG4105C28	cystathionine
THIAE_06415	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
THIAE_06425	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
THIAE_06430	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
THIAE_06435	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
THIAE_06440	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
THIAE_06445	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
THIAE_06450	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
THIAE_06455	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
THIAE_06465	ENOG4105DR5	peptidase
THIAE_06470	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
THIAE_06475	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
THIAE_06480	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
THIAE_06485	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
THIAE_06495	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
THIAE_06505	ENOG4105BZU	Histidine kinase
THIAE_06510	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
THIAE_06515	ENOG4108JPW	Aminotransferase
THIAE_06520	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
THIAE_06525	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
THIAE_06530	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
THIAE_06535	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
THIAE_06540	ENOG4105D06	uba thif-type nad fad binding protein
THIAE_06570	ENOG4105C03	ribonuclease
THIAE_06575	ENOG4108Z03	MAF-like protein
THIAE_06580	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
THIAE_06605	ENOG4107ZT5	Thiol disulfide interchange protein
THIAE_06610	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
THIAE_06620	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
THIAE_06625	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
THIAE_06635	ENOG4105DHP	deoxycytidine triphosphate deaminase
THIAE_06640	ENOG4105D1F	ATP-binding protein
THIAE_06645	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
THIAE_06650	ENOG4105DGN	Electron transport complex
THIAE_06655	ENOG4108R3D	Electron transport complex
THIAE_06665	ENOG4105D6A	Electron transport complex
THIAE_06670	ENOG4108UQQ	Electron transport complex
THIAE_06680	ENOG4105CSM	endonuclease III
THIAE_06695	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
THIAE_06720	ENOG4105DAE	Methylenetetrahydrofolate reductase
THIAE_06725	ENOG4108VWS	Yaeq family
THIAE_06730	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
THIAE_06735	ENOG4105EXZ	Involved in the regulation of ptsG expression by binding and inactivating Mlc (By similarity)
THIAE_06740	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
THIAE_06745	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
THIAE_06765	ENOG4105BZU	Histidine kinase
THIAE_06775	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
THIAE_06805	ENOG4105M6W	Crispr-associated protein, Csy3 family
THIAE_06815	ENOG4105ENG	CRISPR-associated protein, Csy1 family
THIAE_06840	ENOG4105GR3	Histidine kinase
THIAE_06855	ENOG4105CQ7	ATP-dependent helicase
THIAE_06860	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
THIAE_06865	ENOG4105VTW	prevent-host-death family
THIAE_06875	ENOG4108YZY	peptidylprolyl cis-trans isomerase
THIAE_06880	ENOG4107RZZ	dna polymerase iii epsilon subunit
THIAE_06885	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
THIAE_06905	ENOG4105BZU	Histidine kinase
THIAE_06910	ENOG4105DSY	exodeoxyribonuclease V, gamma
THIAE_06915	ENOG4107QKA	exodeoxyribonuclease V beta
THIAE_06920	ENOG4107QYX	exodeoxyribonuclease v alpha
THIAE_06925	ENOG4108UPT	UPF0178 protein
THIAE_06930	ENOG4105K5B	UPF0225 protein
THIAE_06985	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
THIAE_06990	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
THIAE_07010	ENOG4105DG7	nitrate ABC transporter
THIAE_07015	ENOG4108JUA	Transcriptional regulator
THIAE_07040	ENOG4105D64	Mechanosensitive ion channel
THIAE_07055	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
THIAE_07060	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
THIAE_07070	ENOG4105EPW	hflc protein
THIAE_07075	ENOG4107QJR	hflk protein
THIAE_07080	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
THIAE_07085	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
THIAE_07090	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
THIAE_07095	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
THIAE_07100	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
THIAE_07105	ENOG4105K8N	protein family UPF0079, ATPase
THIAE_07110	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
THIAE_07120	ENOG4105CBS	Chea signal transduction histidine kinase
THIAE_07130	ENOG4108VYJ	response regulator receiver protein
THIAE_07135	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THIAE_07140	ENOG4107R21	site-determining protein
THIAE_07145	ENOG4105FZW	flagellar biosynthesis regulator FlhF
THIAE_07150	ENOG4105D7B	Flagellar biosynthesis protein flha
THIAE_07160	ENOG4105D00	flagellar biosynthetic protein flhB
THIAE_07165	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
THIAE_07170	ENOG4105VS8	Flagellar biosynthetic protein fliq
THIAE_07175	ENOG4105CN7	Flagellar biosynthetic protein FliP
THIAE_07180	ENOG4105VTB	flagellar biosynthesis protein fliO
THIAE_07185	ENOG4105DD5	Flagellar motor switch protein
THIAE_07190	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
THIAE_07200	ENOG4105ER2	Ompa motb domain protein
THIAE_07205	ENOG4107RD7	Flagellar Motor Protein, MotA
THIAE_07210	ENOG4108NVR	Methyl-accepting chemotaxis
THIAE_07225	ENOG4108JIR	Flagellum-specific ATP synthase
THIAE_07235	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
THIAE_07240	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
THIAE_07245	ENOG4105X6K	flagellar hook-basal body complex protein fliE
THIAE_07250	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THIAE_07255	ENOG4105BZU	Histidine kinase
THIAE_07265	ENOG4105MQ3	flagellar protein FliS
THIAE_07270	ENOG410801E	Flagellar hook-associated 2 domain-containing protein
THIAE_07275	ENOG41063QE	flagellar protein FlaG
THIAE_07285	ENOG4105I03	Flagellin
THIAE_07325	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
THIAE_07345	ENOG4105DFS	Conserved Protein
THIAE_07350	ENOG4105D2T	synthase
THIAE_07360	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
THIAE_07365	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
THIAE_07370	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
THIAE_07375	ENOG4105I03	Flagellin
THIAE_07385	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
THIAE_07390	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
THIAE_07395	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
THIAE_07400	ENOG4105CGA	flagellar basal-body rod protein FlgG
THIAE_07420	ENOG4105CFH	Aspartokinase
THIAE_07425	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
THIAE_07430	ENOG4105Y3E	Modulates RecA activity (By similarity)
THIAE_07435	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
THIAE_07440	ENOG4107TH8	cina domain protein
THIAE_07445	ENOG4105BZU	Histidine kinase
THIAE_07455	ENOG4105BZU	Histidine kinase
THIAE_07465	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
THIAE_07470	ENOG4107QR8	Thioredoxin
THIAE_07485	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
THIAE_07500	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
THIAE_07505	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
THIAE_07510	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
THIAE_07515	ENOG4105K5M	30s ribosomal protein S16
THIAE_07520	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
THIAE_07530	ENOG4108JU6	CBS domain protein
THIAE_07535	ENOG4105ECY	inositol monophosphatase
THIAE_07540	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
THIAE_07545	ENOG4105EIX	cytochrome c1
THIAE_07550	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
THIAE_07555	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
THIAE_07560	ENOG4107QNR	UPF0135 protein
THIAE_07565	ENOG4105CIH	Imidazole acetol-phosphate transaminase
THIAE_07570	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
THIAE_07575	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
THIAE_07580	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
THIAE_07590	ENOG4105E3A	(ABC) transporter
THIAE_07595	ENOG4105DA5	(ABC) transporter
THIAE_07610	ENOG4107PE3	Mammalian cell entry related domain protein
THIAE_07615	ENOG4105CY3	ABC transporter, permease
THIAE_07620	ENOG4105DHJ	ABC, transporter
THIAE_07635	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
THIAE_07650	ENOG4108IUZ	ABC transporter
THIAE_07655	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
THIAE_07665	ENOG4105D3G	Pseudouridine synthase
THIAE_07680	ENOG4108V1T	peptidylprolyl cis-trans isomerase
THIAE_07685	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
THIAE_07695	ENOG4105CBS	Chea signal transduction histidine kinase
THIAE_07700	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
THIAE_07705	ENOG4108Z6B	deaminase
THIAE_07710	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
THIAE_07715	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
THIAE_07735	ENOG4105EAC	phosphoserine phosphatase
THIAE_07745	ENOG4105M8K	biopolymer transport protein
THIAE_07750	ENOG4105M15	transport protein ExbD
THIAE_07755	ENOG41067XB	TonB family
THIAE_07760	ENOG4105C31	Tryptophanyl-tRNA synthetase
THIAE_07770	ENOG4105NBK	UPF0345 protein
THIAE_07780	ENOG4105D8G	Major Facilitator superfamily
THIAE_07785	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
THIAE_07795	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
THIAE_07800	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
THIAE_07805	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
THIAE_07815	ENOG4105E66	phosphoriboisomerase A
THIAE_07820	ENOG4107QX9	Thiol disulfide interChange protein
THIAE_07825	ENOG41085GJ	domain protein
THIAE_07830	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
THIAE_07840	ENOG4107R88	Chemotaxis protein (CheV)
THIAE_07865	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
THIAE_07870	ENOG4107RK2	ADP-ribose diphosphatase NudE
THIAE_07875	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
THIAE_07880	ENOG4105N2G	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THIAE_07885	ENOG4105C5H	ABC transporter
THIAE_07905	ENOG4108Z9W	Outer membrane porin
THIAE_07915	ENOG4105BZU	Histidine kinase
THIAE_07920	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THIAE_07925	ENOG4105D6J	arsenicaL-resistance protein
THIAE_07930	ENOG4105CAF	HipA N-terminal domain protein
THIAE_07935	ENOG41061P8	Persistence to inhibition of murein or DNA biosynthesis regulatory protein
THIAE_07940	ENOG4105F4R	Transcriptional regulator mode
THIAE_07945	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
THIAE_07950	ENOG4105E0C	molybdate abc transporter
THIAE_07955	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
THIAE_07970	ENOG4105VUH	addiction module killer protein
THIAE_07985	ENOG4105BZU	Histidine kinase
THIAE_07995	ENOG4108RCM	Nitroreductase
THIAE_08000	ENOG4105GR3	Histidine kinase
THIAE_08015	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
THIAE_08020	ENOG4105E3B	Multicopper oxidase
THIAE_08070	ENOG4105FS0	cytoplasmic membrane protein
THIAE_08075	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
THIAE_08085	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
THIAE_08090	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
THIAE_08095	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
THIAE_08100	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
THIAE_08105	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
THIAE_08110	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
THIAE_08115	ENOG4105DC1	bifunctional purine biosynthesis protein purh
THIAE_08120	ENOG4105C12	Phosphoribosylglycinamide synthetase
THIAE_08125	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
THIAE_08130	ENOG4105EHG	Permease protein
THIAE_08140	ENOG4106QJH	hemin transport protein
THIAE_08155	ENOG4105D05	Receptor
THIAE_08165	ENOG4105BZU	Histidine kinase
THIAE_08245	ENOG4105DZ2	Transcriptional regulator
THIAE_08275	ENOG4107RBR	Receptor
THIAE_08300	ENOG4105CM2	brancheD-chain amino acid aminotransferase
THIAE_08305	ENOG4105C8Y	Acetylornithine aminotransferase
THIAE_08310	ENOG4105DBV	ornithine carbamoyltransferase
THIAE_08315	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
THIAE_08325	ENOG4107QMP	dna polymerase iii subunits gamma and tau
THIAE_08335	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
THIAE_08340	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
THIAE_08345	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
THIAE_08355	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
THIAE_08360	ENOG4105CHC	glucokinase (EC 2.7.1.2)
THIAE_08365	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
THIAE_08370	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
THIAE_08380	ENOG4105C2X	Arabinose 5-phosphate isomerase
THIAE_08385	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
THIAE_08405	ENOG4105DAA	L-lactate
THIAE_08410	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
THIAE_08415	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
THIAE_08430	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
THIAE_08435	ENOG4105SYT	Methylenetetrahydrofolate reductase
THIAE_08440	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
THIAE_08480	ENOG4105BZU	Histidine kinase
THIAE_08490	ENOG4107S2Z	UPF0761 membrane protein
THIAE_08495	ENOG4105CN1	protease
THIAE_08500	ENOG41080HT	Transcriptional regulator, arsr family
THIAE_08510	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
THIAE_08515	ENOG4105CNI	cell division protein FtsW
THIAE_08520	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
THIAE_08525	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
THIAE_08530	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
THIAE_08535	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
THIAE_08540	ENOG4105CJN	penicillin-binding protein
THIAE_08550	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
THIAE_08555	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
THIAE_08560	ENOG4108V6E	Cell division protein mraZ
THIAE_08570	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
THIAE_08580	ENOG41082RQ	UPF0102 protein
THIAE_08590	ENOG41067MG	lrgb family
THIAE_08610	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THIAE_08615	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
THIAE_08625	ENOG4105VCC	30S ribosomal protein S21
THIAE_08630	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
THIAE_08635	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
THIAE_08650	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
THIAE_08660	ENOG4105CJW	magnesium transporter
THIAE_08670	ENOG4105CJW	magnesium transporter
THIAE_08675	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
THIAE_08685	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
THIAE_08690	ENOG4105CB5	ATP-dependent DNA helicase recG
THIAE_08695	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
THIAE_08725	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
THIAE_08740	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
THIAE_08785	ENOG4105C3G	gtp-binding protein
THIAE_08790	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
THIAE_08795	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
THIAE_08800	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
THIAE_08810	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
THIAE_08815	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
THIAE_08820	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
THIAE_08825	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
THIAE_08830	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
THIAE_08840	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
THIAE_08865	ENOG4105C8T	Leucyl-tRNA synthetase
THIAE_08900	ENOG4105EXC	Acyl-transferase
THIAE_08925	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
THIAE_08940	ENOG4108YZA	Nitrogen regulatory protein pii
THIAE_08955	ENOG4105I03	Flagellin
THIAE_08965	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
THIAE_08980	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
THIAE_08985	ENOG4105BZS	acriflavin resistance protein
THIAE_09000	ENOG4105DHZ	alpha beta
THIAE_09005	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
THIAE_09035	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
THIAE_09040	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
THIAE_09060	ENOG4105KB2	stringent starvation protein b
THIAE_09065	ENOG4107MKT	Stringent starvation protein a
THIAE_09085	ENOG4105WJX	transcriptional regulator MERR family
THIAE_09090	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
THIAE_09095	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
THIAE_09100	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
THIAE_09105	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
THIAE_09110	ENOG41082NX	50s ribosomal protein l35
THIAE_09115	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
THIAE_09120	ENOG4105C22	threonyL-tRNA synthetase
THIAE_09125	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
THIAE_09135	ENOG4107S7U	Sulfide dehydrogenase
THIAE_09145	ENOG4108K5H	permease YjgP YjgQ family protein
THIAE_09155	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
THIAE_09165	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
THIAE_09185	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
THIAE_09215	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
THIAE_09220	ENOG4105C8Q	Methyl-accepting chemotaxis
THIAE_09230	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
THIAE_09235	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
THIAE_09250	ENOG4105C25	Primosomal protein n'
THIAE_09260	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
THIAE_09275	ENOG4105CXN	decarboxylase
THIAE_09280	ENOG4105EB3	Histidine kinase
THIAE_09285	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
THIAE_09315	ENOG4105D5G	Transposase
THIAE_09325	ENOG4105C5I	Dehydrogenase
THIAE_09330	ENOG4105CH5	extracellular solute-binding protein, family 7
THIAE_09350	ENOG4105UGU	tonB-dependent Receptor
THIAE_09355	ENOG4105D65	subunit l
THIAE_09360	ENOG4108ZE9	Monovalent cation H antiporter subunit C
THIAE_09365	ENOG4107R4Z	monovalent cation h antiporter subunit d
THIAE_09375	ENOG4105W4C	monovalent cation H antiporter subunit F
THIAE_09380	ENOG4105KJM	monovalent cation h antiporter subunit g
THIAE_09390	ENOG4105BZF	Glycosyl transferase (Group 1
THIAE_09400	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
THIAE_09415	ENOG4105EWT	decarboxylase family
THIAE_09420	ENOG4105C1J	atp-dependent rna helicase
THIAE_09425	ENOG4105C8Q	Methyl-accepting chemotaxis
THIAE_09435	ENOG4108V3W	Chemotaxis protein, CheW
THIAE_09440	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
THIAE_09455	ENOG4105C0A	alcohol dehydrogenase
THIAE_09460	ENOG4108YZM	Toxic component of a toxin-antitoxin (TA) module (By similarity)
THIAE_09470	ENOG4105C4R	Atp-dependent dna helicase
THIAE_09490	ENOG4107Y49	methyltransferase
THIAE_09535	ENOG4108AZI	Catalyzes the hydrolysis of 4-amino-2-methyl-5- hydroxymethylpyrimidine pyrophosphate (HMP-PP) to 4-amino-2- methyl-5-hydroxymethylpyrimidine phosphate (HMP-P) (By similarity)
THIAE_09540	ENOG4105XEA	Tetr family transcriptional regulator
THIAE_09555	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
THIAE_09565	ENOG4105PI0	Ferredoxin
THIAE_09595	ENOG4105C0P	Mg chelatase subunit ChlI
THIAE_09660	ENOG4107QMH	DNA methylase
THIAE_09695	ENOG4105C0P	Mg chelatase subunit ChlI
THIAE_09700	ENOG4105W0Z	cytoplasmic protein
THIAE_09710	ENOG4105C75	arginyL-tRNA synthetase
THIAE_09730	ENOG4105C79	DNA protecting protein DprA
THIAE_09735	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
THIAE_09740	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
THIAE_09745	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
THIAE_09755	ENOG4105ES5	Histidine kinase
THIAE_09760	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THIAE_09765	ENOG4105C1A	potassium transporter peripheral membrane
THIAE_09770	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
THIAE_09815	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
THIAE_09820	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
THIAE_09825	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
THIAE_09830	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
THIAE_09835	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
THIAE_09840	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
THIAE_09845	ENOG4107YU2	histidine triad (hIT) protein
THIAE_09850	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
THIAE_09855	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
THIAE_09875	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THIAE_09890	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
THIAE_09930	ENOG4105KNY	Microcompartments protein
THIAE_09935	ENOG4108WT6	Carbon dioxide concentrating mechanism protein
THIAE_09965	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
THIAE_09970	ENOG4108YY7	Invasion gene expression up-regulator SirB
THIAE_09975	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
THIAE_09980	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
THIAE_09985	ENOG4105VEQ	Cold shock protein
THIAE_09995	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
THIAE_10000	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
THIAE_10005	ENOG4105MJ2	Competence protein
THIAE_10010	ENOG4105BZW	Glycerate kinase
THIAE_10020	ENOG4105C3Q	Glycosyl transferase, family 2
THIAE_10030	ENOG4105C4R	Atp-dependent dna helicase
THIAE_10035	ENOG4105K63	Thioredoxin
THIAE_10045	ENOG4105NRA	50s ribosomal protein l31 type b
THIAE_10055	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
THIAE_10060	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
THIAE_10065	ENOG4105CEN	a g-specific adenine glycosylase
THIAE_10070	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
THIAE_10080	ENOG4105BZU	Histidine kinase
THIAE_10085	ENOG4105C2M	dna polymerase I
THIAE_10090	ENOG4105BZU	Histidine kinase
THIAE_10105	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
THIAE_10110	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
THIAE_10115	ENOG4105BZU	Histidine kinase
THIAE_10120	ENOG4108VYJ	response regulator receiver protein
THIAE_10125	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THIAE_10130	ENOG4105BZU	Histidine kinase
THIAE_10140	ENOG4105BZU	Histidine kinase
THIAE_10145	ENOG4105BZU	Histidine kinase
THIAE_10150	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
THIAE_10160	ENOG4105WHD	thiamine biosynthesis protein ThiS
THIAE_10165	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
THIAE_10170	ENOG4105EZN	Cobyrinic acid ac-diamide synthase
THIAE_10180	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
THIAE_10185	ENOG4108YYC	ycei family
THIAE_10190	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
THIAE_10200	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
THIAE_10205	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
THIAE_10210	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
THIAE_10215	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
THIAE_10220	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
THIAE_10225	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
THIAE_10230	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
THIAE_10235	ENOG41081A3	ATP synthase f0, c subunit
THIAE_10240	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
THIAE_10260	ENOG4107QJE	Chromosome Partitioning Protein
THIAE_10265	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
THIAE_10270	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
THIAE_10290	ENOG4107XWI	flavin reductase domain protein, FMN-binding
THIAE_10295	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
THIAE_10305	ENOG41090A1	ferritin
THIAE_10310	ENOG4105GAV	receptor
THIAE_10335	ENOG41076E6	Uroporphyrinogen-III Synthase
THIAE_10340	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
THIAE_10350	ENOG4105CH7	arginosuccinase
THIAE_10365	ENOG4105CEY	Amp-dependent synthetase and ligase
THIAE_10370	ENOG4107SFI	Major Facilitator superfamily
THIAE_10375	ENOG4105BZU	Histidine kinase
THIAE_10380	ENOG4108RRZ	Transcription elongation factor GreB
THIAE_10395	ENOG4106VK6	Flagellar motor protein
THIAE_10400	ENOG4105E14	MotA TolQ exbB proton channel
THIAE_10405	ENOG4105DGW	oligopeptidase A
THIAE_10415	ENOG4105BZU	Histidine kinase
THIAE_10420	ENOG4105BZU	Histidine kinase
THIAE_10425	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
THIAE_10440	ENOG4105HF0	Membrane
THIAE_10445	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
THIAE_10450	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
THIAE_10455	ENOG4105VG0	50S ribosomal protein l34
THIAE_10460	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
THIAE_10465	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
THIAE_10485	ENOG4105VEJ	Heat shock protein
THIAE_10490	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
THIAE_10495	ENOG4105ERG	peptidase m48, ste24p
THIAE_10500	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
THIAE_10505	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
THIAE_10510	ENOG4105CRE	cytochrome C
THIAE_10515	ENOG4108Z33	Thiol disulfide Interchange Protein
THIAE_10520	ENOG4105C7K	acetolactate synthase
THIAE_10525	ENOG4107Y03	Nitroreductase
THIAE_10530	ENOG4105C5Q	Transcriptional regulator
THIAE_10540	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
THIAE_10545	ENOG4105C94	Transporter
THIAE_10550	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
THIAE_10555	ENOG4105ECW	sulfate abc transporter
THIAE_10560	ENOG4107QKW	extracellular solute-binding protein family 1
THIAE_10565	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
THIAE_10595	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
THIAE_10600	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
THIAE_10605	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
THIAE_10610	ENOG4105CC0	LysR family Transcriptional regulator
THIAE_10615	ENOG4105C2I	pirin domain protein
THIAE_10620	ENOG4108YYH	Nadph-dependent fmn reductase
THIAE_10625	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
THIAE_10640	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
THIAE_10650	ENOG4106371	Methyltransferase