locus-tag	class	description
AYJ59_00020	ENOG4105K63	Thioredoxin
AYJ59_00055	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AYJ59_00060	ENOG4107RDB	Major Facilitator
AYJ59_00075	ENOG4105BZU	Histidine kinase
AYJ59_00080	ENOG4106371	Methyltransferase
AYJ59_00090	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
AYJ59_00100	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
AYJ59_00105	ENOG4105PFA	Catalyzes the conversion of 5-hydroxyuridine (ho5U) to 5-methoxyuridine (mo5U) at position 34 in tRNA (By similarity)
AYJ59_00120	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AYJ59_00155	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
AYJ59_00165	ENOG4105ENH	Sulfatase
AYJ59_00170	ENOG4105C4X	radical SAM domain protein
AYJ59_00175	ENOG41062D9	Histidine kinase
AYJ59_00180	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AYJ59_00200	ENOG41061AI	Protein of unknown function (DUF2905)
AYJ59_00205	ENOG4105DGW	oligopeptidase A
AYJ59_00230	ENOG4105D65	subunit l
AYJ59_00235	ENOG4108ZE9	Monovalent cation H antiporter subunit C
AYJ59_00240	ENOG4107R4Z	monovalent cation h antiporter subunit d
AYJ59_00245	ENOG4105SC1	monovalent cation H antiporter subunit E
AYJ59_00250	ENOG4105W4C	monovalent cation H antiporter subunit F
AYJ59_00255	ENOG4105KJM	monovalent cation h antiporter subunit g
AYJ59_00265	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AYJ59_00275	ENOG4105C5Q	Transcriptional regulator
AYJ59_00280	ENOG4107Y03	Nitroreductase
AYJ59_00295	ENOG4108Z33	Thiol disulfide Interchange Protein
AYJ59_00300	ENOG4105CRE	cytochrome C
AYJ59_00305	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
AYJ59_00310	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AYJ59_00325	ENOG4105C8Q	Methyl-accepting chemotaxis
AYJ59_00330	ENOG4105C2M	dna polymerase I
AYJ59_00335	ENOG4105CUV	Homoserine Kinase
AYJ59_00350	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
AYJ59_00365	ENOG4107QZF	nitrite reductase NADPH large subunit
AYJ59_00375	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AYJ59_00390	ENOG4108JUA	Transcriptional regulator
AYJ59_00400	ENOG4105DG7	nitrate ABC transporter
AYJ59_00420	ENOG4105C8P	)-transporter
AYJ59_00425	ENOG4105C8Q	Methyl-accepting chemotaxis
AYJ59_00430	ENOG4105BZU	Histidine kinase
AYJ59_00460	ENOG4105CY0	Metallo-Beta-Lactamase
AYJ59_00470	ENOG4105BZU	Histidine kinase
AYJ59_00480	ENOG4107QWP	ABC-2 type transporter
AYJ59_00485	ENOG4107QWP	ABC-2 type transporter
AYJ59_00490	ENOG4105CJ1	ABC, transporter
AYJ59_00500	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AYJ59_00505	ENOG4105ERG	peptidase m48, ste24p
AYJ59_00510	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
AYJ59_00515	ENOG4105VEJ	Heat shock protein
AYJ59_00525	ENOG4105CEY	Amp-dependent synthetase and ligase
AYJ59_00530	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AYJ59_00555	ENOG4105CJ1	ABC, transporter
AYJ59_00565	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
AYJ59_00585	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AYJ59_00610	ENOG4105C2D	reductase
AYJ59_00650	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AYJ59_00695	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AYJ59_00700	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AYJ59_00705	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
AYJ59_00710	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
AYJ59_00720	ENOG4105HF0	Membrane
AYJ59_00725	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
AYJ59_00730	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
AYJ59_00740	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
AYJ59_00750	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
AYJ59_00765	ENOG4107R1K	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
AYJ59_00770	ENOG4105BZU	Histidine kinase
AYJ59_00780	ENOG4107WP9	Histidine kinase
AYJ59_00790	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AYJ59_00805	ENOG4105DZ2	Transcriptional regulator
AYJ59_00810	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
AYJ59_00830	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
AYJ59_00840	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
AYJ59_00850	ENOG4106TD9	Diguanylate cyclase
AYJ59_00855	ENOG4105C4M	(Ubiquinol oxidase) subunit I
AYJ59_00860	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
AYJ59_00865	ENOG4105CMI	transporter
AYJ59_00870	ENOG4105CJ1	ABC, transporter
AYJ59_00875	ENOG4105D0S	secretion protein (HlyD
AYJ59_00890	ENOG4105EVH	UPF0753 protein
AYJ59_00895	ENOG4108TWJ	NADH dehydrogenase subunit 5
AYJ59_00900	ENOG4105BZU	Histidine kinase
AYJ59_00905	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AYJ59_00915	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
AYJ59_00920	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
AYJ59_00925	ENOG4107QJE	Chromosome Partitioning Protein
AYJ59_00930	ENOG4105FA0	parb-like partition protein
AYJ59_00945	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
AYJ59_00950	ENOG41081A3	ATP synthase f0, c subunit
AYJ59_00955	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AYJ59_00960	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
AYJ59_00965	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
AYJ59_00975	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
AYJ59_00980	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AYJ59_00985	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
AYJ59_00995	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
AYJ59_01035	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
AYJ59_01040	ENOG4105CB5	ATP-dependent DNA helicase recG
AYJ59_01055	ENOG4108I0Y	(ABC) transporter
AYJ59_01090	ENOG4105KME	endoribonuclease L-psp
AYJ59_01095	ENOG4105DSE	periplasmic solute binding protein
AYJ59_01100	ENOG4105DIK	(ABC) transporter
AYJ59_01105	ENOG4105CC5	ABC transporter
AYJ59_01110	ENOG4105CC5	ABC transporter
AYJ59_01120	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AYJ59_01125	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
AYJ59_01135	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AYJ59_01140	ENOG4107RJC	Iron-containing alcohol dehydrogenase
AYJ59_01145	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AYJ59_01150	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AYJ59_01155	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
AYJ59_01160	ENOG4105D49	3-dehydroquinate synthase
AYJ59_01165	ENOG4105DSB	aldose 1-epimerase
AYJ59_01170	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AYJ59_01180	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
AYJ59_01185	ENOG4105BZU	Histidine kinase
AYJ59_01190	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
AYJ59_01195	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
AYJ59_01205	ENOG4105NQN	cytochrome C
AYJ59_01210	ENOG4105BZU	Histidine kinase
AYJ59_01215	ENOG4108XDN	Transcriptional regulator
AYJ59_01220	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
AYJ59_01235	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AYJ59_01290	ENOG4105VTR	Integrase
AYJ59_01345	ENOG4107R11	Transcriptional regulator
AYJ59_01350	ENOG41066VF	YeeE YedE family protein
AYJ59_01380	ENOG4105X9Y	Hydrogenase assembly chaperone hypC hupF
AYJ59_01385	ENOG4105YYZ	Hydrogenase expression formation protein
AYJ59_01395	ENOG4107UY0	rubredoxin
AYJ59_01410	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
AYJ59_01415	ENOG4107RSS	Hydrogenase accessory protein HypB
AYJ59_01420	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AYJ59_01425	ENOG41082MF	Hydrogenase assembly chaperone hypC hupF
AYJ59_01430	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AYJ59_01435	ENOG4105CQS	hydrogenase expression formation protein HypD
AYJ59_01440	ENOG4105C45	hydrogenase expression formation protein (HypE)
AYJ59_01455	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AYJ59_01460	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AYJ59_01465	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AYJ59_01470	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AYJ59_01475	ENOG4105C11	sulfate adenylyltransferase), subunit 2
AYJ59_01480	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
AYJ59_01490	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AYJ59_01495	ENOG4105DPX	Hydrogenase, large subunit
AYJ59_01510	ENOG4105C8H	hydrogenase maturation protein Hypf
AYJ59_01535	ENOG4105VTR	Integrase
AYJ59_01545	ENOG4105E3B	Multicopper oxidase
AYJ59_01560	ENOG4107STQ	Multicopper oxidase
AYJ59_01575	ENOG4108JUA	Transcriptional regulator
AYJ59_01580	ENOG4105I5W	Transporter
AYJ59_01590	ENOG4105D7T	ABC transporter
AYJ59_01595	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
AYJ59_01600	ENOG4105C8Q	Methyl-accepting chemotaxis
AYJ59_01680	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
AYJ59_01685	ENOG4105CJW	magnesium transporter
AYJ59_01690	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
AYJ59_01695	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AYJ59_01705	ENOG4108JQC	penicillin-binding protein 1A
AYJ59_01715	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AYJ59_01720	ENOG4105DSJ	YicC domain protein
AYJ59_01725	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AYJ59_01730	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AYJ59_01740	ENOG4108IJ8	ABC transporter
AYJ59_01765	ENOG4108EX3	reductase
AYJ59_01770	ENOG4105CGK	Exodeoxyribonuclease III
AYJ59_01775	ENOG4105CIY	formyltetrahydrofolate deformylase
AYJ59_01785	ENOG4105M15	transport protein ExbD
AYJ59_01790	ENOG4105M8K	biopolymer transport protein
AYJ59_01795	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
AYJ59_01805	ENOG4105BZU	Histidine kinase
AYJ59_01810	ENOG4107QX9	Thiol disulfide interChange protein
AYJ59_01825	ENOG4105F4I	Transcriptional regulator
AYJ59_01830	ENOG4105C8Q	Methyl-accepting chemotaxis
AYJ59_01835	ENOG4105C7K	acetolactate synthase
AYJ59_01850	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
AYJ59_01860	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
AYJ59_01865	ENOG4105E33	succinate dehydrogenase
AYJ59_01875	ENOG41075H3	AraC family transcriptional regulator
AYJ59_01890	ENOG4105BZU	Histidine kinase
AYJ59_01920	ENOG4105CNG	UPF0061 protein
AYJ59_01945	ENOG4105UGU	tonB-dependent Receptor
AYJ59_01970	ENOG4105CH5	extracellular solute-binding protein, family 7
AYJ59_01980	ENOG4105D07	Signal peptide peptidase, SppA
AYJ59_01985	ENOG4105C8Q	Methyl-accepting chemotaxis
AYJ59_01995	ENOG4105BZU	Histidine kinase
AYJ59_02000	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
AYJ59_02020	ENOG4105EUB	pirin domain protein
AYJ59_02025	ENOG4105CC0	LysR family Transcriptional regulator
AYJ59_02030	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AYJ59_02035	ENOG4105BZS	acriflavin resistance protein
AYJ59_02040	ENOG4108N3W	hemolysin secretion protein
AYJ59_02050	ENOG4107S21	permease
AYJ59_02060	ENOG4105C9U	ATP-dependent DNA helicase RecQ
AYJ59_02085	ENOG4108UPT	UPF0178 protein
AYJ59_02090	ENOG4105BZU	Histidine kinase
AYJ59_02100	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
AYJ59_02105	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AYJ59_02110	ENOG4108RG0	uracil-dna glycosylase
AYJ59_02115	ENOG4105CSW	GntR family transcriptional regulator
AYJ59_02120	ENOG4108RPX	mosc domain containing protein
AYJ59_02135	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AYJ59_02150	ENOG4105EHG	Permease protein
AYJ59_02155	ENOG4105X1Q	TOBE domain protein
AYJ59_02160	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AYJ59_02165	ENOG4105E0A	ABC, transporter
AYJ59_02190	ENOG4105E5H	Transposase
AYJ59_02200	ENOG4105C25	Primosomal protein n'
AYJ59_02230	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
AYJ59_02235	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AYJ59_02240	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
AYJ59_02245	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
AYJ59_02250	ENOG4105MJ2	Competence protein
AYJ59_02260	ENOG4105C7Z	Conserved Protein
AYJ59_02270	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AYJ59_02275	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
AYJ59_02280	ENOG4107YU2	histidine triad (hIT) protein
AYJ59_02285	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
AYJ59_02290	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AYJ59_02295	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AYJ59_02300	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AYJ59_02305	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AYJ59_02310	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
AYJ59_02330	ENOG4105C58	cytochrome c oxidase accessory protein ccog
AYJ59_02355	ENOG4105BZ8	glutamate synthase
AYJ59_02360	ENOG4105CBC	glutamate synthase
AYJ59_02365	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
AYJ59_02375	ENOG4105VW4	glutaredoxin 3
AYJ59_02380	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
AYJ59_02385	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AYJ59_02390	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
AYJ59_02395	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
AYJ59_02400	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AYJ59_02430	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AYJ59_02435	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AYJ59_02445	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AYJ59_02465	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AYJ59_02480	ENOG4105VAW	lrga family
AYJ59_02485	ENOG41067MG	lrgb family
AYJ59_02490	ENOG4105BZU	Histidine kinase
AYJ59_02505	ENOG4106H78	methyltransferase
AYJ59_02510	ENOG4105BZU	Histidine kinase
AYJ59_02515	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AYJ59_02525	ENOG4105F4R	Transcriptional regulator mode
AYJ59_02530	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AYJ59_02535	ENOG4105E0C	molybdate abc transporter
AYJ59_02540	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AYJ59_02555	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AYJ59_02565	ENOG4105BZU	Histidine kinase
AYJ59_02570	ENOG4105W0E	50S ribosomal protein L33
AYJ59_02580	ENOG4105W5Q	DNA repair protein (RadC
AYJ59_02590	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AYJ59_02600	ENOG4105BZU	Histidine kinase
AYJ59_02605	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AYJ59_02615	ENOG4105C94	Transporter
AYJ59_02625	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AYJ59_02640	ENOG4105CHM	Aminotransferase
AYJ59_02645	ENOG4108VPT	UPF0234 protein
AYJ59_02660	ENOG4105CAS	nag kinase
AYJ59_02670	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AYJ59_02670	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AYJ59_02680	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AYJ59_02690	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AYJ59_02695	ENOG4105C9X	ppx gppa phosphatase
AYJ59_02705	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AYJ59_02710	ENOG4105CD3	dihydroorotase
AYJ59_02720	ENOG4105D58	Diguanylate phosphodiesterase
AYJ59_02740	ENOG4108IG5	Transcriptional regulator
AYJ59_02750	ENOG4105EFX	secretion protein, HlyD family
AYJ59_02755	ENOG4105C1J	atp-dependent rna helicase
AYJ59_02760	ENOG4105EWT	decarboxylase family
AYJ59_02765	ENOG4105F4G	Membrane
AYJ59_02775	ENOG4105BZU	Histidine kinase
AYJ59_02785	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AYJ59_02790	ENOG4105EW9	transcriptional regulator AsnC family
AYJ59_02795	ENOG4105C94	Transporter
AYJ59_02800	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
AYJ59_02805	ENOG4105CKI	cobalamin synthesis protein
AYJ59_02810	ENOG4107RSR	Malate quinone oxidoreductase
AYJ59_02815	ENOG4105KTU	Transcriptional regulator, arsr family
AYJ59_02830	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AYJ59_02840	ENOG410642E	Short chain dehydrogenase
AYJ59_02845	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AYJ59_02855	ENOG4105VEQ	Cold shock protein
AYJ59_02860	ENOG4105CIY	formyltetrahydrofolate deformylase
AYJ59_02875	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AYJ59_02890	ENOG4105EYU	Glutamine amido-transferase
AYJ59_02895	ENOG4105M90	Glutamate synthase alpha subunit domain protein
AYJ59_02900	ENOG4105CBC	glutamate synthase
AYJ59_02905	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AYJ59_02910	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AYJ59_02915	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AYJ59_02925	ENOG4108YZA	Nitrogen regulatory protein pii
AYJ59_02945	ENOG4105BZU	Histidine kinase
AYJ59_02950	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AYJ59_02965	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AYJ59_03000	ENOG4105CE1	Ferrous iron transport protein b
AYJ59_03010	ENOG4105DWV	Homoserine O-trans-acetylase
AYJ59_03015	ENOG4105DWV	Homoserine O-trans-acetylase
AYJ59_03020	ENOG4108VIA	integral membrane protein
AYJ59_03025	ENOG4105II7	pyrroline-5-carboxylate reductase
AYJ59_03035	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AYJ59_03035	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AYJ59_03045	ENOG4105DFA	alanine racemase domain protein
AYJ59_03050	ENOG4105CSR	polyphosphate kinase 2
AYJ59_03065	ENOG4105CD3	dihydroorotase
AYJ59_03070	ENOG4105CXT	aspartate transcarbamylase
AYJ59_03075	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AYJ59_03080	ENOG4108UJU	UPF0301 protein
AYJ59_03085	ENOG4105CJ2	(LipO)protein
AYJ59_03090	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AYJ59_03090	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AYJ59_03095	ENOG4105D7Z	glutathione synthase
AYJ59_03105	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AYJ59_03110	ENOG4105SYT	Methylenetetrahydrofolate reductase
AYJ59_03115	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AYJ59_03125	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AYJ59_03130	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AYJ59_03135	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AYJ59_03140	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AYJ59_03150	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AYJ59_03160	ENOG4107ZVW	dihydroneopterin aldolase
AYJ59_03165	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AYJ59_03170	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AYJ59_03175	ENOG4105KTH	gatB Yqey
AYJ59_03180	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AYJ59_03185	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AYJ59_03200	ENOG4105BZU	Histidine kinase
AYJ59_03225	ENOG4107Z6I	Thiamine biosynthesis protein
AYJ59_03240	ENOG4105E98	transcriptional regulator DeoR family
AYJ59_03250	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ59_03255	ENOG4105F38	ABC transporter, permease
AYJ59_03260	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
AYJ59_03270	ENOG4105C8Y	Acetylornithine aminotransferase
AYJ59_03275	ENOG4105CHR	reductase
AYJ59_03285	ENOG4105CPD	ethanolamine ammonia-lyase
AYJ59_03290	ENOG4107FQ9	ethanolamine ammonia-lyase
AYJ59_03295	ENOG4107QW3	Sucrose phosphorylase
AYJ59_03300	ENOG4107Y7Q	pfkb domain protein
AYJ59_03305	ENOG4106N16	had-superfamily hydrolase, subfamily iib
AYJ59_03310	ENOG4107STW	synthase
AYJ59_03330	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AYJ59_03335	ENOG4105EIG	urea carboxylase-associated protein 1
AYJ59_03355	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AYJ59_03400	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AYJ59_03405	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
AYJ59_03415	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
AYJ59_03435	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AYJ59_03450	ENOG4105VAW	lrga family
AYJ59_03455	ENOG41067MG	lrgb family
AYJ59_03460	ENOG4105BZU	Histidine kinase
AYJ59_03475	ENOG4106H78	methyltransferase
AYJ59_03480	ENOG4105BZU	Histidine kinase
AYJ59_03485	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
AYJ59_03495	ENOG4105F4R	Transcriptional regulator mode
AYJ59_03500	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
AYJ59_03505	ENOG4105E0C	molybdate abc transporter
AYJ59_03510	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
AYJ59_03525	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
AYJ59_03535	ENOG4105BZU	Histidine kinase
AYJ59_03540	ENOG4105W0E	50S ribosomal protein L33
AYJ59_03550	ENOG4105W5Q	DNA repair protein (RadC
AYJ59_03560	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AYJ59_03570	ENOG4105BZU	Histidine kinase
AYJ59_03575	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AYJ59_03585	ENOG4105C94	Transporter
AYJ59_03595	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
AYJ59_03610	ENOG4105CHM	Aminotransferase
AYJ59_03615	ENOG4108VPT	UPF0234 protein
AYJ59_03630	ENOG4105CAS	nag kinase
AYJ59_03640	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AYJ59_03640	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AYJ59_03650	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AYJ59_03660	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
AYJ59_03665	ENOG4105C9X	ppx gppa phosphatase
AYJ59_03675	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
AYJ59_03680	ENOG4105CD3	dihydroorotase
AYJ59_03690	ENOG4105D58	Diguanylate phosphodiesterase
AYJ59_03710	ENOG4108IG5	Transcriptional regulator
AYJ59_03720	ENOG4105EFX	secretion protein, HlyD family
AYJ59_03725	ENOG4105C1J	atp-dependent rna helicase
AYJ59_03730	ENOG4105EWT	decarboxylase family
AYJ59_03735	ENOG4105F4G	Membrane
AYJ59_03745	ENOG4105BZU	Histidine kinase
AYJ59_03755	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AYJ59_03760	ENOG4105EW9	transcriptional regulator AsnC family
AYJ59_03765	ENOG4105C94	Transporter
AYJ59_03770	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
AYJ59_03775	ENOG4105CKI	cobalamin synthesis protein
AYJ59_03780	ENOG4107RSR	Malate quinone oxidoreductase
AYJ59_03785	ENOG4105KTU	Transcriptional regulator, arsr family
AYJ59_03800	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AYJ59_03810	ENOG410642E	Short chain dehydrogenase
AYJ59_03815	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
AYJ59_03825	ENOG4105VEQ	Cold shock protein
AYJ59_03830	ENOG4105CIY	formyltetrahydrofolate deformylase
AYJ59_03845	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
AYJ59_03860	ENOG4105EYU	Glutamine amido-transferase
AYJ59_03865	ENOG4105M90	Glutamate synthase alpha subunit domain protein
AYJ59_03870	ENOG4105CBC	glutamate synthase
AYJ59_03875	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AYJ59_03880	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AYJ59_03885	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
AYJ59_03895	ENOG4108YZA	Nitrogen regulatory protein pii
AYJ59_03915	ENOG4105BZU	Histidine kinase
AYJ59_03920	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
AYJ59_03935	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AYJ59_03970	ENOG4105CE1	Ferrous iron transport protein b
AYJ59_03980	ENOG4105DWV	Homoserine O-trans-acetylase
AYJ59_03985	ENOG4105DWV	Homoserine O-trans-acetylase
AYJ59_03990	ENOG4108VIA	integral membrane protein
AYJ59_03995	ENOG4105II7	pyrroline-5-carboxylate reductase
AYJ59_04005	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AYJ59_04005	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AYJ59_04015	ENOG4105DFA	alanine racemase domain protein
AYJ59_04020	ENOG4105CSR	polyphosphate kinase 2
AYJ59_04035	ENOG4105CD3	dihydroorotase
AYJ59_04040	ENOG4105CXT	aspartate transcarbamylase
AYJ59_04045	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
AYJ59_04050	ENOG4108UJU	UPF0301 protein
AYJ59_04055	ENOG4105CJ2	(LipO)protein
AYJ59_04060	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AYJ59_04060	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AYJ59_04065	ENOG4105D7Z	glutathione synthase
AYJ59_04075	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
AYJ59_04080	ENOG4105SYT	Methylenetetrahydrofolate reductase
AYJ59_04085	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
AYJ59_04095	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AYJ59_04100	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
AYJ59_04105	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
AYJ59_04110	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
AYJ59_04120	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AYJ59_04130	ENOG4107ZVW	dihydroneopterin aldolase
AYJ59_04135	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
AYJ59_04140	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AYJ59_04145	ENOG4105KTH	gatB Yqey
AYJ59_04150	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AYJ59_04155	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AYJ59_04170	ENOG4105BZU	Histidine kinase
AYJ59_04195	ENOG4107Z6I	Thiamine biosynthesis protein
AYJ59_04210	ENOG4105E98	transcriptional regulator DeoR family
AYJ59_04220	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ59_04225	ENOG4105F38	ABC transporter, permease
AYJ59_04230	ENOG4105NRK	Binding-protein-dependent transport systems, inner membrane component
AYJ59_04240	ENOG4105C8Y	Acetylornithine aminotransferase
AYJ59_04245	ENOG4105CHR	reductase
AYJ59_04255	ENOG4105CPD	ethanolamine ammonia-lyase
AYJ59_04260	ENOG4107FQ9	ethanolamine ammonia-lyase
AYJ59_04265	ENOG4107QW3	Sucrose phosphorylase
AYJ59_04270	ENOG4107Y7Q	pfkb domain protein
AYJ59_04275	ENOG4106N16	had-superfamily hydrolase, subfamily iib
AYJ59_04280	ENOG4107STW	synthase
AYJ59_04300	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AYJ59_04305	ENOG4105EIG	urea carboxylase-associated protein 1
AYJ59_04325	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AYJ59_04380	ENOG41080HT	Transcriptional regulator, arsr family
AYJ59_04385	ENOG4105CN1	protease
AYJ59_04390	ENOG4108Z0Z	intracellular protease Pfpi family
AYJ59_04400	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
AYJ59_04405	ENOG4108IJF	Heavy metal efflux pump, CzcA
AYJ59_04420	ENOG4105E18	UPF0276 protein
AYJ59_04430	ENOG4105BZU	Histidine kinase
AYJ59_04440	ENOG4105EMN	RNA polymerase sigma factor
AYJ59_04480	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AYJ59_04490	ENOG4105C5H	ABC transporter
AYJ59_04500	ENOG4105IH7	synthase
AYJ59_04505	ENOG4107QX9	Thiol disulfide interChange protein
AYJ59_04510	ENOG4105FQ6	thiopurine methyltransferase
AYJ59_04515	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
AYJ59_04520	ENOG4107RK2	ADP-ribose diphosphatase NudE
AYJ59_04530	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
AYJ59_04545	ENOG4105KXI	murein peptide amidase A
AYJ59_04555	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
AYJ59_04565	ENOG4108K5H	permease YjgP YjgQ family protein
AYJ59_04585	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
AYJ59_04590	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AYJ59_04595	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
AYJ59_04600	ENOG4107MKT	Stringent starvation protein a
AYJ59_04605	ENOG4105KB2	stringent starvation protein b
AYJ59_04640	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
AYJ59_04645	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
AYJ59_04655	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
AYJ59_04665	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
AYJ59_04670	ENOG41082IR	Excinuclease ABC C subunit domain protein
AYJ59_04720	ENOG4105DQU	oxidoreductase, subunit beta
AYJ59_04725	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
AYJ59_04730	ENOG4105C34	Pseudouridine synthase
AYJ59_04745	ENOG4105C2C	drug resistance transporter, Bcr CflA
AYJ59_04755	ENOG4106RE7	Cytochrome
AYJ59_04760	ENOG4107S7U	Sulfide dehydrogenase
AYJ59_04825	ENOG4105KNY	Microcompartments protein
AYJ59_04830	ENOG4108WT6	Carbon dioxide concentrating mechanism protein
AYJ59_04835	ENOG4105KNY	Microcompartments protein
AYJ59_04860	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AYJ59_04870	ENOG4105DUM	transcriptional regulator, lysR family
AYJ59_04885	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
AYJ59_04900	ENOG41082RQ	UPF0102 protein
AYJ59_04910	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
AYJ59_04915	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
AYJ59_04920	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
AYJ59_04925	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
AYJ59_04935	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AYJ59_04940	ENOG4107QK7	reductase
AYJ59_04945	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
AYJ59_04950	ENOG4105FAW	cDP-glucose 4,6-dehydratase
AYJ59_04955	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AYJ59_04960	ENOG4108HHA	Transketolase
AYJ59_04965	ENOG4108IUS	Transketolase
AYJ59_04970	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AYJ59_04995	ENOG4108TJN	glycosyl transferase group 1
AYJ59_05000	ENOG4108TJN	glycosyl transferase group 1
AYJ59_05005	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AYJ59_05010	ENOG4108DMA	Nad-dependent epimerase dehydratase
AYJ59_05020	ENOG4107QKV	phosphomannomutase
AYJ59_05025	ENOG4105D3Q	Sugar transferase
AYJ59_05045	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AYJ59_05055	ENOG4105C22	threonyL-tRNA synthetase
AYJ59_05060	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
AYJ59_05065	ENOG41082NX	50s ribosomal protein l35
AYJ59_05070	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
AYJ59_05075	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AYJ59_05080	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
AYJ59_05085	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AYJ59_05105	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
AYJ59_05110	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AYJ59_05115	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
AYJ59_05120	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
AYJ59_05130	ENOG4105EHM	Aminoglycoside phosphotransferase
AYJ59_05135	ENOG4108S0S	Nucleotidyl transferase
AYJ59_05145	ENOG4105D1Q	UPF0246 protein
AYJ59_05150	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
AYJ59_05155	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
AYJ59_05160	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
AYJ59_05165	ENOG4108Z43	UPF0250 protein
AYJ59_05175	ENOG4105DZ1	carboxypeptidase
AYJ59_05180	ENOG4105CNI	cell division protein FtsW
AYJ59_05185	ENOG4105CJN	penicillin-binding protein
AYJ59_05195	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
AYJ59_05200	ENOG4105DFF	Rod shape-determining protein mreb
AYJ59_05205	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AYJ59_05210	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AYJ59_05215	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AYJ59_05220	ENOG4105D0M	Protease HtpX homolog
AYJ59_05230	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
AYJ59_05240	ENOG4105M15	transport protein ExbD
AYJ59_05245	ENOG4105M8K	biopolymer transport protein
AYJ59_05255	ENOG4105EAC	phosphoserine phosphatase
AYJ59_05275	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AYJ59_05280	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AYJ59_05285	ENOG4108Z6B	deaminase
AYJ59_05290	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AYJ59_05295	ENOG4105CBS	Chea signal transduction histidine kinase
AYJ59_05310	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
AYJ59_05315	ENOG4105C5I	Dehydrogenase
AYJ59_05320	ENOG4105C5H	ABC transporter
AYJ59_05335	ENOG4108KMV	Glycosyl transferase (Group 1
AYJ59_05345	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AYJ59_05355	ENOG41080IJ	Diacylglycerol kinase
AYJ59_05360	ENOG4105D7Z	glutathione synthase
AYJ59_05370	ENOG4107QR8	Thioredoxin
AYJ59_05375	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
AYJ59_05385	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
AYJ59_05390	ENOG4105Y3E	Modulates RecA activity (By similarity)
AYJ59_05395	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AYJ59_05400	ENOG4105CFH	Aspartokinase
AYJ59_05405	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
AYJ59_05415	ENOG4105BZU	Histidine kinase
AYJ59_05430	ENOG4105CTQ	phosphohexokinase
AYJ59_05435	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
AYJ59_05440	ENOG4105DFU	Cell wall formation (By similarity)
AYJ59_05450	ENOG4108BPE	-transporting atpase
AYJ59_05455	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AYJ59_05465	ENOG4105E66	phosphoriboisomerase A
AYJ59_05490	ENOG4105C7B	Threonine dehydratase
AYJ59_05495	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
AYJ59_05505	ENOG4105E07	UPF0149 protein
AYJ59_05510	ENOG4107RAQ	aminopeptidase
AYJ59_05515	ENOG4105D0A	hydroxylase
AYJ59_05520	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
AYJ59_05535	ENOG4108IAB	Phoh family
AYJ59_05540	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AYJ59_05545	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AYJ59_05555	ENOG4108ETH	Formylglycinamide ribotide synthetase
AYJ59_05565	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AYJ59_05570	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
AYJ59_05575	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
AYJ59_05595	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
AYJ59_05600	ENOG4105C87	Aminotransferase class I and II
AYJ59_05605	ENOG4107QHE	Choloylglycine hydrolase
AYJ59_05615	ENOG4105CPC	Aldo Keto reductase
AYJ59_05635	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AYJ59_05665	ENOG4105NBK	UPF0345 protein
AYJ59_05670	ENOG4105CHH	sulfate transporter
AYJ59_05675	ENOG4105BZS	acriflavin resistance protein
AYJ59_05680	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
AYJ59_05685	ENOG4105C31	Tryptophanyl-tRNA synthetase
AYJ59_05690	ENOG4105DJ0	Poly(A) Polymerase
AYJ59_05695	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AYJ59_05700	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
AYJ59_05705	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
AYJ59_05710	ENOG4105E14	MotA TolQ exbB proton channel
AYJ59_05715	ENOG4106VK6	Flagellar motor protein
AYJ59_05720	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
AYJ59_05725	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AYJ59_05735	ENOG4105BZ1	(ABC) transporter
AYJ59_05745	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
AYJ59_05750	ENOG4105D16	lipopolysaccharide heptosyltransferase i
AYJ59_05775	ENOG4105CG5	Glycosyl transferase (Group 1
AYJ59_05785	ENOG4105D16	lipopolysaccharide heptosyltransferase i
AYJ59_05805	ENOG4108Z03	MAF-like protein
AYJ59_05810	ENOG4105C03	ribonuclease
AYJ59_05855	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AYJ59_05860	ENOG4105I03	Flagellin
AYJ59_05875	ENOG4108YZA	Nitrogen regulatory protein pii
AYJ59_05885	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
AYJ59_05890	ENOG4105F0N	pyrophosphate phospho-hydrolase
AYJ59_05895	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AYJ59_05905	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AYJ59_05910	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
AYJ59_05915	ENOG4107QN2	dihydrolipoyl dehydrogenase
AYJ59_05920	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
AYJ59_05925	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AYJ59_05940	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AYJ59_05945	ENOG4105CD8	aminopeptidase N
AYJ59_05990	ENOG4107R88	Chemotaxis protein (CheV)
AYJ59_06000	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
AYJ59_06005	ENOG4108ZC9	flagellar basal-body rod protein flgc
AYJ59_06010	ENOG410822I	Flagellar hook capping protein
AYJ59_06015	ENOG4105BZE	flagellar hook protein, FlgE
AYJ59_06020	ENOG4108KPB	Flagellar basal-body rod protein FlgF
AYJ59_06025	ENOG4105CGA	flagellar basal-body rod protein FlgG
AYJ59_06030	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AYJ59_06035	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
AYJ59_06040	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
AYJ59_06045	ENOG4105E1Q	flagellar hook-associated protein
AYJ59_06050	ENOG4105I03	Flagellin
AYJ59_06055	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
AYJ59_06060	ENOG4108IAJ	Nad-dependent epimerase dehydratase
AYJ59_06065	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
AYJ59_06075	ENOG4105D2T	synthase
AYJ59_06080	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
AYJ59_06100	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AYJ59_06125	ENOG4105F0R	Cytidylyltransferase
AYJ59_06140	ENOG4105I03	Flagellin
AYJ59_06145	ENOG41063QE	flagellar protein FlaG
AYJ59_06150	ENOG4105I03	Flagellin
AYJ59_06160	ENOG4105I03	Flagellin
AYJ59_06165	ENOG4105I03	Flagellin
AYJ59_06170	ENOG4105DTS	flagellar hook-associated
AYJ59_06175	ENOG4105MQ3	flagellar protein FliS
AYJ59_06190	ENOG4105BZU	Histidine kinase
AYJ59_06195	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AYJ59_06200	ENOG4105X6K	flagellar hook-basal body complex protein fliE
AYJ59_06205	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
AYJ59_06210	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AYJ59_06220	ENOG4108JIR	Flagellum-specific ATP synthase
AYJ59_06235	ENOG4108W2P	Methyl-accepting chemotaxis
AYJ59_06240	ENOG4107RD7	Flagellar Motor Protein, MotA
AYJ59_06245	ENOG4105ER2	Ompa motb domain protein
AYJ59_06255	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
AYJ59_06260	ENOG4105DD5	Flagellar motor switch protein
AYJ59_06275	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
AYJ59_06280	ENOG4108Z1B	Cyclase dehydrase
AYJ59_06295	ENOG41090R7	Ferric uptake
AYJ59_06300	ENOG4105BZU	Histidine kinase
AYJ59_06305	ENOG4105C5H	ABC transporter
AYJ59_06310	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AYJ59_06315	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
AYJ59_06320	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AYJ59_06335	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AYJ59_06340	ENOG4107YIM	Involved in the transcription termination process (By similarity)
AYJ59_06345	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AYJ59_06350	ENOG4105C8Q	Methyl-accepting chemotaxis
AYJ59_06355	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
AYJ59_06375	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AYJ59_06380	ENOG4105CTB	Polyprenyl synthetase
AYJ59_06385	ENOG4105D3R	alkyl hydroperoxide reductase
AYJ59_06400	ENOG41080RH	Thioredoxin
AYJ59_06410	ENOG4105BZU	Histidine kinase
AYJ59_06415	ENOG4105WH1	Two component transcriptional regulator luxr family
AYJ59_06445	ENOG4105BZU	Histidine kinase
AYJ59_06450	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
AYJ59_06460	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AYJ59_06465	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AYJ59_06480	ENOG4105C34	Pseudouridine synthase
AYJ59_06485	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
AYJ59_06495	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AYJ59_06500	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
AYJ59_06510	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
AYJ59_06515	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
AYJ59_06520	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
AYJ59_06530	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
AYJ59_06535	ENOG4105CDU	Replicative dna helicase
AYJ59_06545	ENOG41087AY	ADP-Ribose pyrophosphatase
AYJ59_06555	ENOG4107QI1	Mate efflux family protein
AYJ59_06560	ENOG4105K5B	UPF0225 protein
AYJ59_06590	ENOG4105C8Q	Methyl-accepting chemotaxis
AYJ59_06610	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
AYJ59_06615	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AYJ59_06620	ENOG4105VIE	preprotein translocase, subunit YajC
AYJ59_06625	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AYJ59_06630	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
AYJ59_06640	ENOG4108W1A	pseudouridine synthase
AYJ59_06645	ENOG4108ZZ3	UPF0260 protein
AYJ59_06650	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AYJ59_06655	ENOG4108YXA	Membrane
AYJ59_06665	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
AYJ59_06670	ENOG4105D3R	alkyl hydroperoxide reductase
AYJ59_06685	ENOG4105CFP	Peptidase U32
AYJ59_06690	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
AYJ59_06715	ENOG4105C6T	cysteine synthase
AYJ59_06720	ENOG41080ZE	Adenylate cyclase
AYJ59_06735	ENOG4108R5S	membrane
AYJ59_06750	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AYJ59_06755	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ59_06760	ENOG4105BZU	Histidine kinase
AYJ59_06765	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
AYJ59_06770	ENOG4105D64	Mechanosensitive ion channel
AYJ59_06775	ENOG4105D4A	Cell wall formation (By similarity)
AYJ59_06780	ENOG4105C8J	)-transporter
AYJ59_06795	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AYJ59_06800	ENOG4105KUZ	arsenate reductase
AYJ59_06805	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
AYJ59_06815	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
AYJ59_06820	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AYJ59_06825	ENOG4105CE9	30S ribosomal protein S2
AYJ59_06830	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
AYJ59_06835	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AYJ59_06840	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
AYJ59_06850	ENOG4105KNE	Phosphatidate cytidylyltransferase
AYJ59_06855	ENOG4105DZP	Membrane-associated zinc metalloprotease
AYJ59_06870	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AYJ59_06875	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
AYJ59_06880	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AYJ59_06885	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AYJ59_06890	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AYJ59_06895	ENOG4107R88	Chemotaxis protein (CheV)
AYJ59_06900	ENOG4105DVT	helicase
AYJ59_06905	ENOG41072GX	Peptidase M22 Glycoprotease
AYJ59_06920	ENOG4105DDY	UPF0142 protein ycaO
AYJ59_06925	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
AYJ59_06930	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
AYJ59_06935	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AYJ59_06940	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
AYJ59_06945	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AYJ59_06955	ENOG4108DG9	Smr protein MutS2
AYJ59_06960	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AYJ59_06965	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AYJ59_06970	ENOG4108UM1	dedA family
AYJ59_06975	ENOG4108K5P	(LipO)protein
AYJ59_06985	ENOG4105CHM	Aminotransferase
AYJ59_06990	ENOG4105D6E	homoserine dehydrogenase
AYJ59_07000	ENOG4107QID	Threonine synthase
AYJ59_07010	ENOG4105IPS	esterase
AYJ59_07030	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AYJ59_07035	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
AYJ59_07040	ENOG4107S5T	Carbohydrate kinase
AYJ59_07045	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
AYJ59_07050	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
AYJ59_07055	ENOG4105N42	UPF0307 protein
AYJ59_07060	ENOG4108IPJ	Membrane
AYJ59_07065	ENOG4105HDK	L-asparaginase
AYJ59_07070	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
AYJ59_07075	ENOG4105K9H	YciI-like protein
AYJ59_07080	ENOG4107835	probably involved in intracellular septation (By similarity)
AYJ59_07085	ENOG4105DB7	PHP domain protein
AYJ59_07090	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
AYJ59_07095	ENOG4108Z4T	Peptidase M50
AYJ59_07100	ENOG4105FE9	pseudouridine synthase
AYJ59_07120	ENOG4107QX8	SPFH domain, Band 7 family protein
AYJ59_07150	ENOG4105C09	Bile acid
AYJ59_07170	ENOG4105CBC	glutamate synthase
AYJ59_07175	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
AYJ59_07205	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
AYJ59_07210	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
AYJ59_07215	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
AYJ59_07225	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AYJ59_07230	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
AYJ59_07240	ENOG4105K89	arsenate reductase
AYJ59_07250	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AYJ59_07265	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AYJ59_07275	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AYJ59_07285	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
AYJ59_07290	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
AYJ59_07295	ENOG4105CAT	Cytidine monophosphate kinase
AYJ59_07300	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
AYJ59_07310	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AYJ59_07320	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
AYJ59_07325	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AYJ59_07330	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AYJ59_07335	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AYJ59_07340	ENOG4107SEV	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
AYJ59_07355	ENOG4108JQ5	ABC transporter
AYJ59_07360	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AYJ59_07365	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AYJ59_07370	ENOG4105DEF	Extracellular solute-binding protein, family 5
AYJ59_07375	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
AYJ59_07405	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
AYJ59_07410	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
AYJ59_07415	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
AYJ59_07420	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
AYJ59_07430	ENOG4105C5H	ABC transporter
AYJ59_07435	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AYJ59_07440	ENOG4105D60	lipoprotein releasing system transmembrane protein
AYJ59_07445	ENOG4105EN6	Membrane
AYJ59_07450	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
AYJ59_07460	ENOG4108JA2	transcriptioN-repair coupling factor
AYJ59_07470	ENOG4105VCH	membrane
AYJ59_07475	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
AYJ59_07480	ENOG4107QMS	site-determining protein
AYJ59_07485	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
AYJ59_07505	ENOG4107QTH	restriction modification system DNA specificity domain
AYJ59_07515	ENOG4108F3G	Type I restriction-modification system, R subunit
AYJ59_07535	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AYJ59_07540	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
AYJ59_07550	ENOG4105BZU	Histidine kinase
AYJ59_07555	ENOG4107QIJ	Aconitate hydratase 2
AYJ59_07580	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
AYJ59_07590	ENOG4107QJE	Chromosome Partitioning Protein
AYJ59_07605	ENOG4108ESY	Metal dependent phosphohydrolase
AYJ59_07635	ENOG4105C4W	S-formylglutathione hydrolase
AYJ59_07655	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
AYJ59_07680	ENOG4107QTF	adenylosuccinate lyase
AYJ59_07685	ENOG4105EZE	Cupin 4 family protein
AYJ59_07705	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AYJ59_07710	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
AYJ59_07720	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
AYJ59_07725	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AYJ59_07730	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
AYJ59_07735	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AYJ59_07740	ENOG4105CHV	Transcription elongation factor NusA
AYJ59_07745	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
AYJ59_07760	ENOG4107QN1	sodium solute
AYJ59_07765	ENOG41062QD	Membrane
AYJ59_07770	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AYJ59_07775	ENOG4105C0B	DNA polymerase III (alpha subunit)
AYJ59_07780	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
AYJ59_07785	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
AYJ59_07790	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AYJ59_07795	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
AYJ59_07805	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
AYJ59_07810	ENOG4105BZU	Histidine kinase
AYJ59_07815	ENOG4105CDY	transcriptional regulatory protein
AYJ59_07830	ENOG4108R99	pseudouridine synthase
AYJ59_07835	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AYJ59_07840	ENOG41075W9	High frequency lysogenization protein HflD homolog
AYJ59_07850	ENOG4105EIN	peptidylprolyl cis-trans isomerase
AYJ59_07855	ENOG4108VYJ	response regulator receiver protein
AYJ59_07860	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AYJ59_07865	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
AYJ59_07875	ENOG4105EPW	hflc protein
AYJ59_07880	ENOG4107QJR	hflk protein
AYJ59_07885	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
AYJ59_07890	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
AYJ59_07895	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
AYJ59_07900	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
AYJ59_07905	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
AYJ59_07910	ENOG4105K8N	protein family UPF0079, ATPase
AYJ59_07915	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AYJ59_07920	ENOG4105BZU	Histidine kinase
AYJ59_07925	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
AYJ59_07945	ENOG4108UT2	hemolysin iii
AYJ59_07950	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AYJ59_07955	ENOG410829K	Lysine exporter protein (Lyse ygga)
AYJ59_07960	ENOG4105DIJ	Phosphoethanolamine transferase
AYJ59_07965	ENOG41080IJ	Diacylglycerol kinase
AYJ59_07975	ENOG4108RCM	Nitroreductase
AYJ59_07980	ENOG4105VEQ	Cold shock protein
AYJ59_08000	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
AYJ59_08005	ENOG4105D6S	protein involved in catabolism of external DNA
AYJ59_08025	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AYJ59_08030	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
AYJ59_08040	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AYJ59_08045	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
AYJ59_08055	ENOG4105DHP	deoxycytidine triphosphate deaminase
AYJ59_08060	ENOG4105D1F	ATP-binding protein
AYJ59_08065	ENOG4105BZU	Histidine kinase
AYJ59_08070	ENOG410812K	response regulator receiver protein
AYJ59_08075	ENOG4108MGY	Histidine kinase
AYJ59_08085	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AYJ59_08090	ENOG4105DGN	Electron transport complex
AYJ59_08095	ENOG4108R3D	Electron transport complex
AYJ59_08105	ENOG4105D6A	Electron transport complex
AYJ59_08115	ENOG4105DZB	Electron transport complex
AYJ59_08120	ENOG4105CSM	endonuclease III
AYJ59_08150	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AYJ59_08180	ENOG4108RCM	Nitroreductase
AYJ59_08200	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AYJ59_08210	ENOG4105VRT	cytoplasmic protein
AYJ59_08220	ENOG4107QN2	dihydrolipoyl dehydrogenase
AYJ59_08225	ENOG4107QSN	dihydrolipoamide acetyltransferase
AYJ59_08230	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
AYJ59_08235	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
AYJ59_08245	ENOG4105BZU	Histidine kinase
AYJ59_08250	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AYJ59_08255	ENOG4105CRE	cytochrome C
AYJ59_08260	ENOG4108JU6	CBS domain protein
AYJ59_08265	ENOG4105ECY	inositol monophosphatase
AYJ59_08270	ENOG4105BZU	Histidine kinase
AYJ59_08275	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AYJ59_08280	ENOG4105EIX	cytochrome c1
AYJ59_08285	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AYJ59_08290	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
AYJ59_08295	ENOG4107QNR	UPF0135 protein
AYJ59_08300	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AYJ59_08305	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AYJ59_08310	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
AYJ59_08320	ENOG4105E3A	(ABC) transporter
AYJ59_08325	ENOG4105DA5	(ABC) transporter
AYJ59_08340	ENOG4107PE3	Mammalian cell entry related domain protein
AYJ59_08345	ENOG4105CY3	ABC transporter, permease
AYJ59_08350	ENOG4105DHJ	ABC, transporter
AYJ59_08365	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
AYJ59_08375	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
AYJ59_08380	ENOG4108IUZ	ABC transporter
AYJ59_08385	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
AYJ59_08390	ENOG4105CJW	magnesium transporter
AYJ59_08395	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
AYJ59_08400	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
AYJ59_08405	ENOG4105EB3	Histidine kinase
AYJ59_08410	ENOG4105DS1	cytochrome b561
AYJ59_08425	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
AYJ59_08430	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AYJ59_08435	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AYJ59_08440	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
AYJ59_08445	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AYJ59_08455	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
AYJ59_08460	ENOG4105W49	UPF0434 protein
AYJ59_08465	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
AYJ59_08470	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
AYJ59_08480	ENOG4105DAN	ATP-dependent protease
AYJ59_08515	ENOG4105CQ7	ATP-dependent helicase
AYJ59_08525	ENOG4105VMP	Transcriptional regulator
AYJ59_08535	ENOG4105BZU	Histidine kinase
AYJ59_08545	ENOG4107QX8	SPFH domain, Band 7 family protein
AYJ59_08570	ENOG4105CHR	reductase
AYJ59_08600	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
AYJ59_08655	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
AYJ59_08660	ENOG4105CMQ	Chloride channel
AYJ59_08665	ENOG4105C54	Major Facilitator superfamily
AYJ59_08685	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AYJ59_08690	ENOG4108JDX	DNA polymerase iii, epsilon subunit
AYJ59_08700	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AYJ59_08710	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AYJ59_08715	ENOG4105E9H	Lytic Murein transglycosylase
AYJ59_08720	ENOG4107SC1	transglycosylase
AYJ59_08725	ENOG4105C8N	cysteinyl-tRNA synthetase
AYJ59_08730	ENOG4105CX6	glutaminyL-tRNA synthetase
AYJ59_08740	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
AYJ59_08745	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
AYJ59_08755	ENOG4105CK2	sodium dicarboxylate symporter
AYJ59_08765	ENOG4108ZAI	phosphatidylglycerophosphatase a
AYJ59_08770	ENOG4105CDH	Citrulline--aspartate ligase
AYJ59_08775	ENOG4105DJ4	phosphatidylserine decarboxylase
AYJ59_08780	ENOG4108YZA	Nitrogen regulatory protein pii
AYJ59_08790	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AYJ59_08795	ENOG4105CUX	Signal transduction histidine kinase
AYJ59_08825	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AYJ59_08835	ENOG4105KCK	Peptidoglycan-associated lipoprotein
AYJ59_08840	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
AYJ59_08850	ENOG4105M8F	Biopolymer transport protein exbD tolR
AYJ59_08855	ENOG4105E02	MotA TolQ exbB proton channel
AYJ59_08860	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
AYJ59_08870	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
AYJ59_08875	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
AYJ59_08880	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AYJ59_08885	ENOG4105C9M	aspartyl-trna synthetase
AYJ59_08895	ENOG4105E1F	short-chain dehydrogenase reductase
AYJ59_08900	ENOG4105D78	K07001 NTE family protein
AYJ59_08910	ENOG4105DKQ	ROK family
AYJ59_08920	ENOG4105ED9	Protein of unknown function (DUF455)
AYJ59_08935	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
AYJ59_08940	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AYJ59_08945	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AYJ59_08955	ENOG4105C2C	drug resistance transporter, Bcr CflA
AYJ59_08960	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AYJ59_08970	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
AYJ59_08980	ENOG4108YZN	class I peptide chain release factor
AYJ59_08985	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AYJ59_08985	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AYJ59_08995	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AYJ59_09000	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
AYJ59_09005	ENOG4105CFG	Acts as a chaperone (By similarity)
AYJ59_09010	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AYJ59_09015	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
AYJ59_09020	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AYJ59_09025	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
AYJ59_09040	ENOG4105BZU	Histidine kinase
AYJ59_09045	ENOG4105D58	Diguanylate phosphodiesterase
AYJ59_09055	ENOG4105KT5	UmuD protein
AYJ59_09065	ENOG4105BZU	Histidine kinase
AYJ59_09070	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
AYJ59_09085	ENOG4105BZU	Histidine kinase
AYJ59_09095	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AYJ59_09100	ENOG4105C8S	subunit m
AYJ59_09110	ENOG41080FQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AYJ59_09115	ENOG4105DF2	NADH dehydrogenase subunit j
AYJ59_09120	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AYJ59_09125	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
AYJ59_09130	ENOG4108IEH	NADH dehydrogenase subunit g
AYJ59_09135	ENOG4107QIZ	NADH dehydrogenase
AYJ59_09145	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AYJ59_09150	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AYJ59_09155	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AYJ59_09160	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AYJ59_09170	ENOG4107EJC	Preprotein translocase subunit SecG
AYJ59_09175	ENOG4105CP7	Triose-phosphate isomerase
AYJ59_09180	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AYJ59_09185	ENOG4105EEI	dihydropteroate synthase
AYJ59_09190	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AYJ59_09195	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AYJ59_09200	ENOG4105HBR	Rna-binding protein
AYJ59_09205	ENOG4105C28	cystathionine
AYJ59_09210	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
AYJ59_09220	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
AYJ59_09225	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
AYJ59_09230	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AYJ59_09235	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AYJ59_09240	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AYJ59_09245	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AYJ59_09250	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
AYJ59_09260	ENOG4105DR5	peptidase
AYJ59_09265	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AYJ59_09270	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AYJ59_09275	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AYJ59_09280	ENOG4107RJX	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AYJ59_09300	ENOG4107S7U	Sulfide dehydrogenase
AYJ59_09305	ENOG4105FUQ	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
AYJ59_09310	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
AYJ59_09325	ENOG4105BZU	Histidine kinase
AYJ59_09330	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AYJ59_09340	ENOG4105ECP	epimerase
AYJ59_09345	ENOG4105CR8	Transcriptional regulator
AYJ59_09350	ENOG4105DS1	cytochrome b561
AYJ59_09360	ENOG4105C1J	atp-dependent rna helicase
AYJ59_09365	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
AYJ59_09370	ENOG4105C8Q	Methyl-accepting chemotaxis
AYJ59_09380	ENOG4105BZU	Histidine kinase
AYJ59_09385	ENOG4105BZU	Histidine kinase
AYJ59_09390	ENOG4108ZXC	Two component transcriptional regulator, luxr family
AYJ59_09400	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AYJ59_09405	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AYJ59_09410	ENOG4105CW7	secretion protein, HlyD family
AYJ59_09420	ENOG4105GR3	Histidine kinase
AYJ59_09425	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
AYJ59_09430	ENOG4105BZW	Glycerate kinase
AYJ59_09455	ENOG4105C3Q	Glycosyl transferase, family 2
AYJ59_09460	ENOG4108ZFX	Mannosyl-3-phosphoglycerate phosphatase
AYJ59_09470	ENOG4108KMM	Diguanylate cyclase
AYJ59_09495	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AYJ59_09500	ENOG4105WMR	Protein CrcB homolog
AYJ59_09505	ENOG4105D1H	recombination factor protein RarA
AYJ59_09510	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
AYJ59_09515	ENOG4105CNU	cell division protein FtsK
AYJ59_09520	ENOG4105C3M	thioredoxin reductase
AYJ59_09525	ENOG4108V1T	peptidylprolyl cis-trans isomerase
AYJ59_09530	ENOG4105EGD	dinuclear metal center protein, YbgI family
AYJ59_09540	ENOG4105C8Q	Methyl-accepting chemotaxis
AYJ59_09545	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AYJ59_09550	ENOG4105BZU	Histidine kinase
AYJ59_09560	ENOG4108V3W	Chemotaxis protein, CheW
AYJ59_09565	ENOG4108VYJ	response regulator receiver protein
AYJ59_09580	ENOG4108V3W	Chemotaxis protein, CheW
AYJ59_09585	ENOG4105CBS	Chea signal transduction histidine kinase
AYJ59_09590	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
AYJ59_09595	ENOG4108VYJ	response regulator receiver protein
AYJ59_09600	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
AYJ59_09605	ENOG4107R21	site-determining protein
AYJ59_09610	ENOG4105FZW	flagellar biosynthesis regulator FlhF
AYJ59_09615	ENOG4105D7B	Flagellar biosynthesis protein flha
AYJ59_09620	ENOG4105D00	flagellar biosynthetic protein flhB
AYJ59_09625	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
AYJ59_09630	ENOG4105VS8	Flagellar biosynthetic protein fliq
AYJ59_09635	ENOG4105CN7	Flagellar biosynthetic protein FliP
AYJ59_09640	ENOG4105VTB	flagellar biosynthesis protein fliO
AYJ59_09645	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
AYJ59_09650	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
AYJ59_09655	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
AYJ59_09660	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
AYJ59_09665	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
AYJ59_09670	ENOG4105C3F	Signal peptidase i
AYJ59_09675	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
AYJ59_09680	ENOG4105C0H	protease
AYJ59_09690	ENOG4108IYU	L-aspartate oxidase
AYJ59_09695	ENOG4108V3W	Chemotaxis protein, CheW
AYJ59_09700	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
AYJ59_09705	ENOG4105CRK	lysyL-tRNA synthetase
AYJ59_09715	ENOG4105DQ4	alcohol dehydrogenase
AYJ59_09730	ENOG4105CF7	AraC family transcriptional regulator
AYJ59_09735	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
AYJ59_09755	ENOG4105C8Q	Methyl-accepting chemotaxis
AYJ59_09760	ENOG4105BZ1	(ABC) transporter
AYJ59_09765	ENOG4105F8V	Hydrolase, tatD family
AYJ59_09770	ENOG4107QRG	dna polymerase iii
AYJ59_09775	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AYJ59_09780	ENOG4105HHA	aminodeoxychorismate lyase
AYJ59_09790	ENOG4105CRQ	synthase (Component I)
AYJ59_09795	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
AYJ59_09800	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
AYJ59_09805	ENOG4105CHR	reductase
AYJ59_09810	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
AYJ59_09815	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AYJ59_09820	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
AYJ59_09825	ENOG4105VGS	50s ribosomal protein l32
AYJ59_09835	ENOG4108UHJ	MAF-like protein
AYJ59_09840	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AYJ59_09845	ENOG4105EI2	Pseudouridine synthase
AYJ59_09850	ENOG4105C03	ribonuclease
AYJ59_09855	ENOG4105KJF	protein tyrosine phosphatase
AYJ59_09860	ENOG4105D3G	Pseudouridine synthase
AYJ59_09875	ENOG4105T95	Thiol disulfide interChange protein
AYJ59_09880	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AYJ59_09885	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
AYJ59_09890	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
AYJ59_09895	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
AYJ59_09900	ENOG4105K5M	30s ribosomal protein S16
AYJ59_09905	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AYJ59_09910	ENOG4105CGY	Dna recombination protein
AYJ59_09930	ENOG4105D7Q	type ii secretion system
AYJ59_09935	ENOG4107QHF	type ii secretion system protein e
AYJ59_09960	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AYJ59_09965	ENOG4108ZP8	Acetolactate synthase small subunit
AYJ59_09970	ENOG4105C7K	acetolactate synthase
AYJ59_09975	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
AYJ59_09980	ENOG4105D0M	Protease HtpX homolog
AYJ59_09985	ENOG41090A4	Pterin carbinolamine dehydratase
AYJ59_09990	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
AYJ59_09995	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AYJ59_10000	ENOG4107QKW	extracellular solute-binding protein family 1
AYJ59_10015	ENOG4106RE7	Cytochrome
AYJ59_10020	ENOG4108JQ1	Dehydrogenase
AYJ59_10025	ENOG4105CQB	FAD linked oxidase domain protein
AYJ59_10030	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AYJ59_10035	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AYJ59_10045	ENOG4105CUT	histidyl-tRNA synthetase
AYJ59_10055	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
AYJ59_10060	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AYJ59_10065	ENOG4108Z4V	iron-sulfur cluster assembly
AYJ59_10070	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
AYJ59_10085	ENOG4105ECY	inositol monophosphatase
AYJ59_10100	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AYJ59_10105	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AYJ59_10110	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AYJ59_10115	ENOG4107QP8	phosphohexose isomerase
AYJ59_10120	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
AYJ59_10125	ENOG4105VFE	sira family
AYJ59_10130	ENOG4105ERG	peptidase m48, ste24p
AYJ59_10150	ENOG41088H4	Diheme cytochrome SoxA (Sulfur oxidation)
AYJ59_10160	ENOG4105C01	Dihydroxy-acid dehydratase
AYJ59_10165	ENOG4107QZM	n-acetylglutamate synthase
AYJ59_10170	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
AYJ59_10175	ENOG4105M2J	Glutaredoxin
AYJ59_10180	ENOG4105CAQ	asparagine synthetase
AYJ59_10185	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
AYJ59_10195	ENOG4108UB3	Thiamine monophosphate
AYJ59_10200	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AYJ59_10205	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AYJ59_10210	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
AYJ59_10215	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
AYJ59_10220	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
AYJ59_10225	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
AYJ59_10230	ENOG4105CPF	Cell wall formation (By similarity)
AYJ59_10235	ENOG4105DFU	Cell wall formation (By similarity)
AYJ59_10250	ENOG4105JRK	feS assembly protein SufD
AYJ59_10255	ENOG4105C3K	feS assembly ATPase SufC
AYJ59_10260	ENOG4105DIW	FeS assembly protein SUFB
AYJ59_10275	ENOG4105FDK	ABC transporter
AYJ59_10280	ENOG4105FAV	ABC, transporter
AYJ59_10285	ENOG4105C8Q	Methyl-accepting chemotaxis
AYJ59_10295	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AYJ59_10300	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
AYJ59_10305	ENOG4105C8Q	Methyl-accepting chemotaxis
AYJ59_10310	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
AYJ59_10315	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
AYJ59_10320	ENOG4105CNI	cell division protein FtsW
AYJ59_10325	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
AYJ59_10330	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
AYJ59_10335	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
AYJ59_10340	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
AYJ59_10345	ENOG4105CJN	penicillin-binding protein
AYJ59_10355	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AYJ59_10360	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
AYJ59_10365	ENOG4108V6E	Cell division protein mraZ
AYJ59_10385	ENOG4107SDU	Methyl-accepting chemotaxis
AYJ59_10395	ENOG4105CQ7	ATP-dependent helicase
AYJ59_10400	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
AYJ59_10415	ENOG4105BZU	Histidine kinase
AYJ59_10425	ENOG4105CV6	ABC transporter, permease
AYJ59_10430	ENOG4108I0Y	(ABC) transporter
AYJ59_10435	ENOG4108UJV	acyl-CoA thioesterase i
AYJ59_10470	ENOG4105CJ3	phosphate transporter
AYJ59_10475	ENOG4105BZU	Histidine kinase
AYJ59_10480	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
AYJ59_10485	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AYJ59_10490	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AYJ59_10495	ENOG4105C8U	phosphate abc transporter
AYJ59_10505	ENOG4105C5F	glutamine synthetase
AYJ59_10515	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AYJ59_10520	ENOG4105C8Y	Acetylornithine aminotransferase
AYJ59_10525	ENOG4105DBV	ornithine carbamoyltransferase
AYJ59_10530	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
AYJ59_10535	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
AYJ59_10540	ENOG4107QMP	dna polymerase iii subunits gamma and tau
AYJ59_10555	ENOG4105CEP	NADH dehydrogenase
AYJ59_10565	ENOG4105Y49	secretion protein, HlyD family
AYJ59_10585	ENOG4105CZK	Aspartate kinase
AYJ59_10590	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
AYJ59_10595	ENOG4108JPW	Aminotransferase
AYJ59_10615	ENOG4108RRZ	Transcription elongation factor GreB
AYJ59_10630	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
AYJ59_10635	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
AYJ59_10640	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
AYJ59_10650	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AYJ59_10655	ENOG4105CHC	glucokinase (EC 2.7.1.2)
AYJ59_10660	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
AYJ59_10665	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AYJ59_10675	ENOG4105C2X	Arabinose 5-phosphate isomerase
AYJ59_10680	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
AYJ59_10690	ENOG4105D4P	Coproporphyrinogen iii oxidase
AYJ59_10695	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AYJ59_10700	ENOG4105CVE	Lytic murein transglycosylase
AYJ59_10705	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
AYJ59_10710	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AYJ59_10715	ENOG4105DTN	riboflavin biosynthesis protein ribF
AYJ59_10720	ENOG4105CJR	Integral membrane protein (MviN
AYJ59_10725	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
AYJ59_10750	ENOG4105HDD	phospholipase
AYJ59_10770	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
AYJ59_10775	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
AYJ59_10780	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
AYJ59_10790	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
AYJ59_10805	ENOG4105C8T	Leucyl-tRNA synthetase
AYJ59_10815	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
AYJ59_10820	ENOG4108JU5	Magnesium and cobalt efflux protein
AYJ59_10825	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
AYJ59_10830	ENOG4105C9A	Phoh family
AYJ59_10835	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AYJ59_10845	ENOG4105BZU	Histidine kinase
AYJ59_10850	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AYJ59_10855	ENOG4108VAU	general secretion pathway protein G
AYJ59_10885	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
AYJ59_10890	ENOG4108UJD	30S ribosomal protein S9
AYJ59_10895	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AYJ59_10915	ENOG4105BZU	Histidine kinase
AYJ59_10920	ENOG4105CKI	cobalamin synthesis protein
AYJ59_10945	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
AYJ59_10950	ENOG4105UUH	Domain of unknown function DUF302 
AYJ59_10970	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
AYJ59_10975	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
AYJ59_10980	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
AYJ59_10985	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AYJ59_10990	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AYJ59_10995	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
AYJ59_11000	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
AYJ59_11005	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AYJ59_11010	ENOG4105C12	Phosphoribosylglycinamide synthetase
AYJ59_11025	ENOG4105FAE	von Willebrand factor, type A
AYJ59_11040	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
AYJ59_11045	ENOG4105DUM	transcriptional regulator, lysR family
AYJ59_11075	ENOG41077A9	carbonic anhydrase
AYJ59_11090	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
AYJ59_11095	ENOG4105BZU	Histidine kinase
AYJ59_11105	ENOG4107XWI	flavin reductase domain protein, FMN-binding
AYJ59_11115	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
AYJ59_11120	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
AYJ59_11125	ENOG4105BZU	Histidine kinase
AYJ59_11135	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AYJ59_11140	ENOG4105BZU	Histidine kinase
AYJ59_11145	ENOG4105M7P	phage repressor
AYJ59_11155	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AYJ59_11160	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
AYJ59_11170	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AYJ59_11180	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
AYJ59_11185	ENOG4105C7N	Xanthine uracil vitamin C permease
AYJ59_11200	ENOG4108W0P	ABC transporter
AYJ59_11205	ENOG4105EHG	Permease protein
AYJ59_11210	ENOG4105S10	periplasmic binding protein
AYJ59_11215	ENOG4105D05	Receptor
AYJ59_11235	ENOG4105EUP	HipA domain protein
AYJ59_11270	ENOG4108C33	Resolvase
AYJ59_11305	ENOG4105C3G	gtp-binding protein
AYJ59_11310	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
AYJ59_11315	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
AYJ59_11320	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AYJ59_11335	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AYJ59_11340	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
AYJ59_11345	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
AYJ59_11350	ENOG4105D06	uba thif-type nad fad binding protein
AYJ59_11355	ENOG4106VK6	Flagellar motor protein
AYJ59_11360	ENOG4107RD7	Flagellar Motor Protein, MotA
AYJ59_11365	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AYJ59_11370	ENOG410681U	heavy metal transport detoxification protein
AYJ59_11390	ENOG4105BZU	Histidine kinase
AYJ59_11395	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AYJ59_11400	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
AYJ59_11405	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
AYJ59_11420	ENOG4105E14	MotA TolQ exbB proton channel
AYJ59_11430	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
AYJ59_11435	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
AYJ59_11440	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
AYJ59_11445	ENOG4105VFE	sira family
AYJ59_11450	ENOG4105DR5	peptidase
AYJ59_11455	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
AYJ59_11460	ENOG4105BZN	citrate synthase
AYJ59_11465	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
AYJ59_11470	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AYJ59_11475	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AYJ59_11480	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
AYJ59_11485	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
AYJ59_11490	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AYJ59_11495	ENOG4105K46	50S ribosomal protein l27
AYJ59_11500	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
AYJ59_11505	ENOG4105EAH	synthase
AYJ59_11545	ENOG4108FPN	Integrase
AYJ59_11550	ENOG4108UUM	single-stranded DNA-binding protein
AYJ59_11555	ENOG4107RDB	Major Facilitator
AYJ59_11565	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
AYJ59_11575	ENOG4105CUZ	uba thif-type nad fad binding protein
AYJ59_11585	ENOG4108ZT0	50S ribosomal protein l17
AYJ59_11590	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AYJ59_11595	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AYJ59_11600	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AYJ59_11605	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AYJ59_11610	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AYJ59_11615	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AYJ59_11620	ENOG4105VPB	50S ribosomal protein L30
AYJ59_11625	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AYJ59_11630	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AYJ59_11635	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AYJ59_11640	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AYJ59_11645	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
AYJ59_11650	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AYJ59_11655	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AYJ59_11660	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AYJ59_11665	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AYJ59_11670	ENOG41083MP	50s ribosomal protein l29
AYJ59_11675	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AYJ59_11680	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AYJ59_11685	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AYJ59_11690	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AYJ59_11695	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AYJ59_11700	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AYJ59_11705	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
AYJ59_11710	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AYJ59_11715	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AYJ59_11720	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AYJ59_11725	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AYJ59_11730	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
AYJ59_11735	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
AYJ59_11740	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AYJ59_11745	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AYJ59_11750	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
AYJ59_11755	ENOG4108VZM	50s ribosomal protein L10
AYJ59_11760	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AYJ59_11765	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AYJ59_11770	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
AYJ59_11775	ENOG4105PM1	preprotein translocase subunit SecE
AYJ59_11785	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AYJ59_11820	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
AYJ59_11830	ENOG4108UKZ	OsmC family
AYJ59_11840	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AYJ59_11845	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AYJ59_11850	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AYJ59_11855	ENOG4107QYG	anthranilate phosphoribosyltransferase
AYJ59_11860	ENOG4105DDQ	anthranilate synthase
AYJ59_11865	ENOG4105CRQ	synthase (Component I)
AYJ59_11870	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AYJ59_11875	ENOG4105DJV	ribulose-phosphate 3-epimerase
AYJ59_11885	ENOG4105C8V	SAICAR synthetase
AYJ59_11890	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
AYJ59_11900	ENOG4105D2N	Aldolase
AYJ59_11905	ENOG4105CA9	Pyruvate kinase
AYJ59_11910	ENOG4105BZA	Phosphoglycerate kinase
AYJ59_11915	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
AYJ59_11920	ENOG4105CV1	Transketolase (EC 2.2.1.1)
AYJ59_11945	ENOG41076HS	cation diffusion facilitator family transporter
AYJ59_11950	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
AYJ59_11960	ENOG4105VNG	YcgL domain-containing protein
AYJ59_11965	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
AYJ59_11995	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AYJ59_12025	ENOG4105W39	Membrane
AYJ59_12050	ENOG4105DC7	peptidase M24
AYJ59_12055	ENOG4108JPW	Aminotransferase
AYJ59_12060	ENOG4105CH2	amidohydrolase
AYJ59_12070	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AYJ59_12075	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AYJ59_12090	ENOG4107Y49	methyltransferase
AYJ59_12095	ENOG4105C4R	Atp-dependent dna helicase
AYJ59_12100	ENOG4105C0A	alcohol dehydrogenase
AYJ59_12105	ENOG4105UYK	outer membrane protein a
AYJ59_12115	ENOG4105BZU	Histidine kinase
AYJ59_12145	ENOG4105C0P	Mg chelatase subunit ChlI
AYJ59_12205	ENOG4105W0Z	cytoplasmic protein
AYJ59_12210	ENOG4105BZU	Histidine kinase
AYJ59_12220	ENOG4105C75	arginyL-tRNA synthetase
AYJ59_12225	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
AYJ59_12230	ENOG4108VYJ	response regulator receiver protein
AYJ59_12235	ENOG4105C79	DNA protecting protein DprA
AYJ59_12240	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
AYJ59_12245	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
AYJ59_12250	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AYJ59_12260	ENOG4105ES5	Histidine kinase
AYJ59_12265	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AYJ59_12270	ENOG4105C1A	potassium transporter peripheral membrane
AYJ59_12275	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AYJ59_12295	ENOG4107F58	2'-5' rna ligase
AYJ59_12300	ENOG4105D1S	lipid A biosynthesis
AYJ59_12305	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AYJ59_12310	ENOG4105BZU	Histidine kinase
AYJ59_12330	ENOG4105D05	Receptor
AYJ59_12335	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AYJ59_12350	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AYJ59_12355	ENOG4105EHG	Permease protein
AYJ59_12360	ENOG4107R4I	Periplasmic binding protein
AYJ59_12365	ENOG4106QJH	hemin transport protein
AYJ59_12370	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
AYJ59_12380	ENOG41090A1	ferritin
AYJ59_12405	ENOG4107R9T	Catalyzes the formation of 5-methyl-uridine at position 54 (m5U54) in all tRNAs (By similarity)
AYJ59_12410	ENOG4105BZU	Histidine kinase
AYJ59_12415	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
AYJ59_12440	ENOG4105CJW	magnesium transporter
AYJ59_12460	ENOG4105DS1	cytochrome b561
AYJ59_12465	ENOG4108R3E	Dna-3-methyladenine glycosylase i
AYJ59_12490	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
AYJ59_12495	ENOG4105BZU	Histidine kinase
AYJ59_12515	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AYJ59_12520	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AYJ59_12525	ENOG4108ZAF	Molybdopterin
AYJ59_12530	ENOG4105M00	molybdopterin converting factor, subunit 1
AYJ59_12535	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AYJ59_12555	ENOG4105D52	delta-aminolevulinic acid dehydratase
AYJ59_12560	ENOG4105E2X	shikimate dehydrogenase
AYJ59_12565	ENOG4105BZU	Histidine kinase
AYJ59_12570	ENOG4108Z0R	Transferase
AYJ59_12580	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AYJ59_12590	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AYJ59_12595	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
AYJ59_12600	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AYJ59_12610	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
AYJ59_12635	ENOG4108ESX	Receptor
AYJ59_12660	ENOG4105EHV	domain protein
AYJ59_12665	ENOG4105UYK	outer membrane protein a
AYJ59_12675	ENOG4105CBX	hi0933 family
AYJ59_12685	ENOG4105BZU	Histidine kinase
AYJ59_12705	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
AYJ59_12715	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
AYJ59_12720	ENOG4105C4R	Atp-dependent dna helicase
AYJ59_12725	ENOG4105K63	Thioredoxin
AYJ59_12740	ENOG4105NRA	50s ribosomal protein l31 type b
AYJ59_12750	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
AYJ59_12760	ENOG4105D58	Diguanylate phosphodiesterase
AYJ59_12765	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
AYJ59_12770	ENOG4105CEN	a g-specific adenine glycosylase
AYJ59_12775	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
AYJ59_12785	ENOG4105CSA	Coproporphyrinogen iii oxidase
AYJ59_12790	ENOG4105C6K	Malic enzyme
AYJ59_12800	ENOG4105KK7	inner membrane protein YiaW
AYJ59_12805	ENOG4105EFX	secretion protein, HlyD family
AYJ59_12840	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AYJ59_12850	ENOG4105CH7	arginosuccinase
AYJ59_12855	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)