locus-tag	class	description
AYJ59_00020	COG3118	belongs to the thioredoxin family
AYJ59_00055	COG0714	Associated with various cellular activities
AYJ59_00060	COG2814	Major facilitator Superfamily
AYJ59_00075	COG0745	RESPONSE REGULATOR receiver
AYJ59_00075	COG3706	GGDEF domain
AYJ59_00080	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AYJ59_00090	COG0741	lytic transglycosylase activity
AYJ59_00100	COG2226	methyltransferase
AYJ59_00105	COG0500	methyltransferase
AYJ59_00115	COG2205	protein histidine kinase activity
AYJ59_00115	COG0784	Response regulator, receiver
AYJ59_00120	COG0714	Associated with various cellular activities
AYJ59_00140	COG2304	oxidoreductase activity
AYJ59_00155	COG2814	Major facilitator Superfamily
AYJ59_00165	COG3119	arylsulfatase activity
AYJ59_00170	COG0641	radical SAM
AYJ59_00175	COG2205	protein histidine kinase activity
AYJ59_00180	COG2204	response regulator
AYJ59_00205	COG0339	signal peptide processing
AYJ59_00210	COG0432	Pfam Uncharacterised protein family UPF0047
AYJ59_00225	COG1283	sodium-dependent phosphate transmembrane transporter activity
AYJ59_00230	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AYJ59_00230	COG2111	Na H antiporter
AYJ59_00235	COG1006	Multisubunit Na H antiporter MnhC subunit
AYJ59_00240	COG0651	ATP synthesis coupled electron transport
AYJ59_00250	COG2212	antiporter activity
AYJ59_00255	COG1320	monovalent cation:proton antiporter activity
AYJ59_00265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYJ59_00275	COG0583	DNA-binding transcription factor activity
AYJ59_00280	COG0778	Nitroreductase
AYJ59_00290	COG0028	Belongs to the TPP enzyme family
AYJ59_00295	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYJ59_00300	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AYJ59_00305	COG1333	cytochrome c biogenesis protein
AYJ59_00310	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AYJ59_00325	COG0840	transmembrane signaling receptor activity
AYJ59_00330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AYJ59_00330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AYJ59_00335	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AYJ59_00350	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AYJ59_00365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYJ59_00375	COG1162	GTPase activity
AYJ59_00400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ59_00420	COG0471	metal ion transport
AYJ59_00425	COG0840	transmembrane signaling receptor activity
AYJ59_00460	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AYJ59_00470	COG3706	GGDEF domain
AYJ59_00480	COG0842	Transport permease protein
AYJ59_00485	COG0842	Transport permease protein
AYJ59_00490	COG1131	(ABC) transporter
AYJ59_00500	COG0009	L-threonylcarbamoyladenylate synthase
AYJ59_00505	COG4783	chaperone-mediated protein folding
AYJ59_00510	COG0408	coproporphyrinogen oxidase activity
AYJ59_00525	COG0318	PFAM AMP-dependent synthetase and ligase
AYJ59_00530	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AYJ59_00555	COG1131	(ABC) transporter
AYJ59_00565	COG2813	Specifically methylates the guanine in position
AYJ59_00570	COG1280	lysine exporter protein (LysE YggA)
AYJ59_00585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AYJ59_00610	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ59_00650	COG0187	DNA topoisomerase II activity
AYJ59_00695	COG0745	RESPONSE REGULATOR receiver
AYJ59_00700	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AYJ59_00710	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AYJ59_00720	COG0730	response to heat
AYJ59_00725	COG0594	ribonuclease P activity
AYJ59_00730	COG0706	membrane insertase activity
AYJ59_00740	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AYJ59_00750	COG1739	Uncharacterized protein family UPF0029
AYJ59_00765	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AYJ59_00765	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AYJ59_00770	COG5001	Diguanylate cyclase
AYJ59_00770	COG3300	MHYT domain
AYJ59_00780	COG2205	protein histidine kinase activity
AYJ59_00790	COG2204	response regulator
AYJ59_00805	COG0583	DNA-binding transcription factor activity
AYJ59_00810	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
AYJ59_00830	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AYJ59_00840	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AYJ59_00850	COG3706	GGDEF domain
AYJ59_00855	COG1271	oxidase subunit
AYJ59_00860	COG1294	oxidase, subunit
AYJ59_00865	COG0842	Transport permease protein
AYJ59_00870	COG0842	Transport permease protein
AYJ59_00870	COG1129	ABC transporter
AYJ59_00875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYJ59_00890	COG3002	Belongs to the UPF0753 family
AYJ59_00895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AYJ59_00900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AYJ59_00900	COG2205	protein histidine kinase activity
AYJ59_00905	COG3437	response regulator, receiver
AYJ59_00915	COG0445	tRNA wobble uridine modification
AYJ59_00920	COG0357	Ribosomal RNA small subunit methyltransferase G
AYJ59_00925	COG1192	Involved in chromosome partitioning
AYJ59_00930	COG1475	DNA binding
AYJ59_00945	COG0356	it plays a direct role in the translocation of protons across the membrane
AYJ59_00950	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AYJ59_00955	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AYJ59_00960	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AYJ59_00965	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AYJ59_00975	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AYJ59_00980	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AYJ59_00985	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AYJ59_00995	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AYJ59_01035	COG3161	chorismate lyase activity
AYJ59_01040	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AYJ59_01055	COG4181	ATPase activity
AYJ59_01085	COG0004	ammonium transporteR
AYJ59_01095	COG0803	Belongs to the bacterial solute-binding protein 9 family
AYJ59_01100	COG1121	(ABC) transporter
AYJ59_01105	COG1321	iron dependent repressor
AYJ59_01105	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AYJ59_01110	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AYJ59_01120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AYJ59_01125	COG1758	RNA polymerase activity
AYJ59_01135	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AYJ59_01140	COG1454	alcohol dehydrogenase
AYJ59_01145	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AYJ59_01150	COG0194	GDP metabolic process
AYJ59_01155	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AYJ59_01160	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AYJ59_01165	COG0676	glucose-6-phosphate 1-epimerase activity
AYJ59_01180	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AYJ59_01185	COG5001	Diguanylate cyclase
AYJ59_01185	COG3300	MHYT domain
AYJ59_01190	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AYJ59_01195	COG1854	S-ribosylhomocysteine lyase activity
AYJ59_01205	COG3258	Cytochrome c
AYJ59_01210	COG1366	Belongs to the anti-sigma-factor antagonist family
AYJ59_01215	COG0789	Transcriptional regulator
AYJ59_01220	COG0415	Belongs to the DNA photolyase family
AYJ59_01235	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AYJ59_01290	COG0582	viral genome integration into host DNA
AYJ59_01345	COG0583	DNA-binding transcription factor activity
AYJ59_01350	COG2391	methyltransferase activity
AYJ59_01370	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AYJ59_01380	COG0298	carbon dioxide binding
AYJ59_01390	COG1773	rubredoxin
AYJ59_01410	COG0375	protein maturation
AYJ59_01420	COG2204	response regulator
AYJ59_01430	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AYJ59_01460	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AYJ59_01465	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AYJ59_01475	COG0175	sulfate reduction
AYJ59_01480	COG2895	sulfate adenylyltransferase (ATP) activity
AYJ59_01485	COG0471	metal ion transport
AYJ59_01485	COG3273	potassium ion transport
AYJ59_01490	COG0175	sulfate reduction
AYJ59_01505	COG4191	Histidine kinase
AYJ59_01535	COG0582	viral genome integration into host DNA
AYJ59_01540	COG3328	transposase activity
AYJ59_01545	COG2132	Multicopper oxidase
AYJ59_01560	COG2132	Multicopper oxidase
AYJ59_01575	COG3604	Transcriptional regulator
AYJ59_01580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYJ59_01585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ59_01590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYJ59_01590	COG1116	anion transmembrane transporter activity
AYJ59_01595	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
AYJ59_01600	COG0840	transmembrane signaling receptor activity
AYJ59_01620	COG4964	Belongs to the GSP D family
AYJ59_01680	COG0189	ligase activity
AYJ59_01685	COG2239	Acts as a magnesium transporter
AYJ59_01690	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AYJ59_01695	COG0563	adenylate kinase activity
AYJ59_01715	COG2095	MarC family integral membrane protein
AYJ59_01720	COG1561	YicC-like family, N-terminal region
AYJ59_01725	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AYJ59_01730	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AYJ59_01740	COG0517	IMP dehydrogenase activity
AYJ59_01740	COG1125	glycine betaine transport
AYJ59_01765	COG0543	2 iron, 2 sulfur cluster binding
AYJ59_01765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AYJ59_01770	COG0708	Exodeoxyribonuclease III
AYJ59_01775	COG0788	formyltetrahydrofolate deformylase activity
AYJ59_01785	COG0848	biopolymer transport protein
AYJ59_01790	COG0811	peptide transport
AYJ59_01795	COG1444	tRNA N-acetyltransferase activity
AYJ59_01805	COG5001	Diguanylate cyclase
AYJ59_01805	COG5002	protein histidine kinase activity
AYJ59_01810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AYJ59_01825	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AYJ59_01830	COG0840	transmembrane signaling receptor activity
AYJ59_01860	COG1053	succinate dehydrogenase
AYJ59_01875	COG2207	Transcriptional regulator
AYJ59_01915	COG0390	transport system, permease component
AYJ59_01920	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AYJ59_01970	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AYJ59_01980	COG0616	signal peptide processing
AYJ59_01985	COG0840	transmembrane signaling receptor activity
AYJ59_02000	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AYJ59_02020	COG1741	Belongs to the pirin family
AYJ59_02025	COG0583	DNA-binding transcription factor activity
AYJ59_02035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYJ59_02040	COG0840	transmembrane signaling receptor activity
AYJ59_02050	COG0701	Predicted permease
AYJ59_02060	COG0514	ATP-dependent DNA helicase (RecQ)
AYJ59_02085	COG1671	Belongs to the UPF0178 family
AYJ59_02100	COG0742	ribosomal rna small subunit methyltransferase
AYJ59_02105	COG0133	tryptophan synthase activity
AYJ59_02110	COG1573	uracil-dna glycosylase
AYJ59_02120	COG2258	MOSC domain
AYJ59_02135	COG4206	TonB-dependent receptor
AYJ59_02155	COG3585	molybdate ion transport
AYJ59_02165	COG1120	ATPase activity
AYJ59_02190	COG4372	Transposase
AYJ59_02200	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AYJ59_02230	COG2226	methyltransferase
AYJ59_02235	COG0596	Alpha beta hydrolase
AYJ59_02240	COG0156	8-amino-7-oxononanoate synthase activity
AYJ59_02245	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AYJ59_02250	COG1040	competence protein
AYJ59_02260	COG1331	Highly conserved protein containing a thioredoxin domain
AYJ59_02270	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AYJ59_02275	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AYJ59_02280	COG0537	adenosine 5'-monophosphoramidase activity
AYJ59_02285	COG0140	phosphoribosyl-ATP diphosphatase activity
AYJ59_02290	COG0107	imidazoleglycerol-phosphate synthase activity
AYJ59_02295	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AYJ59_02300	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AYJ59_02305	COG0131	Imidazoleglycerol-phosphate dehydratase
AYJ59_02310	COG3278	Belongs to the heme-copper respiratory oxidase family
AYJ59_02330	COG0348	domain, Protein
AYJ59_02340	COG2217	Heavy metal translocating P-type atpase
AYJ59_02355	COG0493	'glutamate synthase
AYJ59_02360	COG0070	glutamate synthase
AYJ59_02360	COG0067	glutamate synthase
AYJ59_02360	COG0069	glutamate synthase activity
AYJ59_02365	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AYJ59_02370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AYJ59_02380	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AYJ59_02385	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AYJ59_02390	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AYJ59_02395	COG0167	dihydroorotate dehydrogenase activity
AYJ59_02400	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AYJ59_02430	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AYJ59_02430	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AYJ59_02435	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AYJ59_02445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AYJ59_02465	COG0552	protein localization to endoplasmic reticulum
AYJ59_02470	COG0612	Peptidase, M16
AYJ59_02475	COG0612	Peptidase, M16
AYJ59_02480	COG1380	Effector of murein hydrolase LrgA
AYJ59_02485	COG1346	cytolysis
AYJ59_02490	COG3706	GGDEF domain
AYJ59_02505	COG0742	ribosomal rna small subunit methyltransferase
AYJ59_02515	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AYJ59_02540	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AYJ59_02545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AYJ59_02555	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AYJ59_02565	COG3706	GGDEF domain
AYJ59_02570	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AYJ59_02580	COG2003	Belongs to the UPF0758 family
AYJ59_02590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AYJ59_02600	COG0784	Response regulator, receiver
AYJ59_02600	COG2205	protein histidine kinase activity
AYJ59_02615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYJ59_02625	COG0756	dUTP diphosphatase activity
AYJ59_02640	COG0436	Aminotransferase
AYJ59_02645	COG1666	GTP binding
AYJ59_02660	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AYJ59_02670	COG0840	transmembrane signaling receptor activity
AYJ59_02670	COG0840	transmembrane signaling receptor activity
AYJ59_02695	COG0248	Ppx GppA phosphatase
AYJ59_02705	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AYJ59_02710	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AYJ59_02720	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AYJ59_02725	COG1012	belongs to the aldehyde dehydrogenase family
AYJ59_02740	COG1309	transcriptional regulator
AYJ59_02750	COG1566	PFAM secretion protein HlyD family protein
AYJ59_02755	COG0513	Belongs to the DEAD box helicase family
AYJ59_02760	COG1611	Belongs to the LOG family
AYJ59_02765	COG0628	permease
AYJ59_02785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AYJ59_02790	COG1522	sequence-specific DNA binding
AYJ59_02795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYJ59_02800	COG1469	GTP cyclohydrolase I activity
AYJ59_02805	COG0523	cobalamin synthesis protein
AYJ59_02810	COG0579	oxidoreductase
AYJ59_02815	COG0640	Transcriptional regulator
AYJ59_02830	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AYJ59_02845	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AYJ59_02855	COG1278	Cold shock
AYJ59_02860	COG0788	formyltetrahydrofolate deformylase activity
AYJ59_02875	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AYJ59_02875	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYJ59_02890	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AYJ59_02895	COG2218	PFAM glutamate synthase alpha subunit domain protein
AYJ59_02900	COG0069	glutamate synthase activity
AYJ59_02905	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AYJ59_02910	COG0519	Catalyzes the synthesis of GMP from XMP
AYJ59_02910	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AYJ59_02915	COG0456	acetyltransferase
AYJ59_02920	COG0004	ammonium transporteR
AYJ59_02925	COG0347	Belongs to the P(II) protein family
AYJ59_02940	COG0469	pyruvate kinase activity
AYJ59_02945	COG3706	GGDEF domain
AYJ59_02950	COG0509	glycine decarboxylation via glycine cleavage system
AYJ59_02965	COG0019	diaminopimelate decarboxylase activity
AYJ59_03000	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AYJ59_03010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AYJ59_03010	COG2813	Specifically methylates the guanine in position
AYJ59_03015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AYJ59_03020	COG0762	integral membrane protein
AYJ59_03030	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AYJ59_03035	COG0840	transmembrane signaling receptor activity
AYJ59_03035	COG0840	transmembrane signaling receptor activity
AYJ59_03065	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AYJ59_03070	COG0540	Belongs to the ATCase OTCase family
AYJ59_03075	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AYJ59_03080	COG1678	Uncharacterized ACR, COG1678
AYJ59_03085	COG1477	protein flavinylation
AYJ59_03090	COG0840	transmembrane signaling receptor activity
AYJ59_03090	COG0840	transmembrane signaling receptor activity
AYJ59_03095	COG0189	ligase activity
AYJ59_03105	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AYJ59_03110	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AYJ59_03115	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AYJ59_03120	COG5001	Diguanylate cyclase
AYJ59_03120	COG2203	Gaf domain
AYJ59_03120	COG3706	GGDEF domain
AYJ59_03120	COG4251	negative regulation of phosphorylation
AYJ59_03125	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AYJ59_03135	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AYJ59_03135	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AYJ59_03140	COG1968	undecaprenyl-diphosphatase activity
AYJ59_03150	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AYJ59_03160	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AYJ59_03165	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AYJ59_03170	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AYJ59_03175	COG1610	YqeY-like protein
AYJ59_03200	COG3706	GGDEF domain
AYJ59_03225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYJ59_03240	COG1349	DNA-binding transcription factor activity
AYJ59_03250	COG3842	ATPase activity
AYJ59_03255	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYJ59_03260	COG1177	transmembrane transport
AYJ59_03275	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ59_03285	COG4303	Ethanolamine ammonia lyase large subunit
AYJ59_03290	COG4302	ethanolamine ammonia-lyase activity
AYJ59_03300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYJ59_03305	COG3100	YcgL domain-containing protein
AYJ59_03305	COG0561	phosphatase activity
AYJ59_03310	COG0438	transferase activity, transferring glycosyl groups
AYJ59_03330	COG0439	Biotin carboxylase
AYJ59_03335	COG3665	Urea carboxylase-associated protein
AYJ59_03355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ59_03400	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AYJ59_03400	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AYJ59_03405	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AYJ59_03415	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AYJ59_03435	COG0552	protein localization to endoplasmic reticulum
AYJ59_03440	COG0612	Peptidase, M16
AYJ59_03445	COG0612	Peptidase, M16
AYJ59_03450	COG1380	Effector of murein hydrolase LrgA
AYJ59_03455	COG1346	cytolysis
AYJ59_03460	COG3706	GGDEF domain
AYJ59_03475	COG0742	ribosomal rna small subunit methyltransferase
AYJ59_03485	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AYJ59_03510	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AYJ59_03515	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AYJ59_03525	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AYJ59_03535	COG3706	GGDEF domain
AYJ59_03540	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AYJ59_03550	COG2003	Belongs to the UPF0758 family
AYJ59_03560	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AYJ59_03570	COG2205	protein histidine kinase activity
AYJ59_03570	COG0784	Response regulator, receiver
AYJ59_03585	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYJ59_03595	COG0756	dUTP diphosphatase activity
AYJ59_03610	COG0436	Aminotransferase
AYJ59_03615	COG1666	GTP binding
AYJ59_03630	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AYJ59_03640	COG0840	transmembrane signaling receptor activity
AYJ59_03640	COG0840	transmembrane signaling receptor activity
AYJ59_03665	COG0248	Ppx GppA phosphatase
AYJ59_03675	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AYJ59_03680	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AYJ59_03690	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AYJ59_03695	COG1012	belongs to the aldehyde dehydrogenase family
AYJ59_03710	COG1309	transcriptional regulator
AYJ59_03720	COG1566	PFAM secretion protein HlyD family protein
AYJ59_03725	COG0513	Belongs to the DEAD box helicase family
AYJ59_03730	COG1611	Belongs to the LOG family
AYJ59_03735	COG0628	permease
AYJ59_03755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AYJ59_03760	COG1522	sequence-specific DNA binding
AYJ59_03765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AYJ59_03770	COG1469	GTP cyclohydrolase I activity
AYJ59_03775	COG0523	cobalamin synthesis protein
AYJ59_03780	COG0579	oxidoreductase
AYJ59_03785	COG0640	Transcriptional regulator
AYJ59_03800	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AYJ59_03815	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AYJ59_03825	COG1278	Cold shock
AYJ59_03830	COG0788	formyltetrahydrofolate deformylase activity
AYJ59_03845	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AYJ59_03845	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYJ59_03860	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AYJ59_03865	COG2218	PFAM glutamate synthase alpha subunit domain protein
AYJ59_03870	COG0069	glutamate synthase activity
AYJ59_03875	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AYJ59_03880	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AYJ59_03880	COG0519	Catalyzes the synthesis of GMP from XMP
AYJ59_03885	COG0456	acetyltransferase
AYJ59_03890	COG0004	ammonium transporteR
AYJ59_03895	COG0347	Belongs to the P(II) protein family
AYJ59_03910	COG0469	pyruvate kinase activity
AYJ59_03915	COG3706	GGDEF domain
AYJ59_03920	COG0509	glycine decarboxylation via glycine cleavage system
AYJ59_03935	COG0019	diaminopimelate decarboxylase activity
AYJ59_03970	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AYJ59_03980	COG2813	Specifically methylates the guanine in position
AYJ59_03980	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AYJ59_03985	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AYJ59_03990	COG0762	integral membrane protein
AYJ59_04000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AYJ59_04005	COG0840	transmembrane signaling receptor activity
AYJ59_04005	COG0840	transmembrane signaling receptor activity
AYJ59_04035	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AYJ59_04040	COG0540	Belongs to the ATCase OTCase family
AYJ59_04045	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AYJ59_04050	COG1678	Uncharacterized ACR, COG1678
AYJ59_04055	COG1477	protein flavinylation
AYJ59_04060	COG0840	transmembrane signaling receptor activity
AYJ59_04060	COG0840	transmembrane signaling receptor activity
AYJ59_04065	COG0189	ligase activity
AYJ59_04075	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AYJ59_04080	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AYJ59_04085	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AYJ59_04090	COG5001	Diguanylate cyclase
AYJ59_04090	COG4251	negative regulation of phosphorylation
AYJ59_04090	COG3706	GGDEF domain
AYJ59_04090	COG2203	Gaf domain
AYJ59_04095	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AYJ59_04105	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AYJ59_04105	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AYJ59_04110	COG1968	undecaprenyl-diphosphatase activity
AYJ59_04120	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AYJ59_04130	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AYJ59_04135	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AYJ59_04140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AYJ59_04145	COG1610	YqeY-like protein
AYJ59_04170	COG3706	GGDEF domain
AYJ59_04195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AYJ59_04210	COG1349	DNA-binding transcription factor activity
AYJ59_04220	COG3842	ATPase activity
AYJ59_04225	COG1176	ABC-type spermidine putrescine transport system, permease component I
AYJ59_04230	COG1177	transmembrane transport
AYJ59_04245	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ59_04255	COG4303	Ethanolamine ammonia lyase large subunit
AYJ59_04260	COG4302	ethanolamine ammonia-lyase activity
AYJ59_04270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AYJ59_04275	COG3100	YcgL domain-containing protein
AYJ59_04275	COG0561	phosphatase activity
AYJ59_04280	COG0438	transferase activity, transferring glycosyl groups
AYJ59_04300	COG0439	Biotin carboxylase
AYJ59_04305	COG3665	Urea carboxylase-associated protein
AYJ59_04325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ59_04380	COG0640	Transcriptional regulator
AYJ59_04385	COG0793	Belongs to the peptidase S41A family
AYJ59_04390	COG0693	protein deglycase activity
AYJ59_04400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYJ59_04405	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AYJ59_04420	COG3220	belongs to the UPF0276 family
AYJ59_04430	COG5001	Diguanylate cyclase
AYJ59_04430	COG3300	MHYT domain
AYJ59_04440	COG1595	DNA-templated transcription, initiation
AYJ59_04480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYJ59_04505	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AYJ59_04510	COG0500	methyltransferase
AYJ59_04515	COG1011	Hydrolase
AYJ59_04520	COG0494	nUDIX hydrolase
AYJ59_04530	COG0556	nucleotide-excision repair
AYJ59_04545	COG2866	Carboxypeptidase
AYJ59_04555	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AYJ59_04565	COG0795	lipopolysaccharide-transporting ATPase activity
AYJ59_04600	COG0625	glutathione transferase activity
AYJ59_04605	COG2969	positive regulation of protein catabolic process
AYJ59_04640	COG3425	synthase
AYJ59_04645	COG1304	FMN binding
AYJ59_04655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYJ59_04670	COG2827	Endonuclease containing a URI domain
AYJ59_04680	COG1959	2 iron, 2 sulfur cluster binding
AYJ59_04700	COG1959	2 iron, 2 sulfur cluster binding
AYJ59_04720	COG1013	pyruvate-flavodoxin oxidoreductase activity
AYJ59_04725	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AYJ59_04725	COG0674	pyruvate-flavodoxin oxidoreductase activity
AYJ59_04730	COG0564	pseudouridine synthase activity
AYJ59_04740	COG1714	RDD family
AYJ59_04745	COG2814	Major facilitator Superfamily
AYJ59_04760	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYJ59_04860	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AYJ59_04870	COG0583	DNA-binding transcription factor activity
AYJ59_04885	COG1074	ATP-dependent DNA helicase activity
AYJ59_04900	COG0792	nuclease activity
AYJ59_04910	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AYJ59_04945	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AYJ59_04960	COG3959	Transketolase, thiamine diphosphate binding domain
AYJ59_04965	COG3958	Transketolase
AYJ59_04970	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AYJ59_05005	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AYJ59_05020	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AYJ59_05025	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AYJ59_05040	COG1793	dna ligase
AYJ59_05045	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AYJ59_05055	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AYJ59_05060	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AYJ59_05065	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AYJ59_05070	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AYJ59_05075	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AYJ59_05080	COG0072	phenylalanine-tRNA ligase activity
AYJ59_05080	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYJ59_05085	COG0776	regulation of translation
AYJ59_05105	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AYJ59_05110	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AYJ59_05115	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AYJ59_05120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYJ59_05135	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AYJ59_05145	COG3022	response to hydroperoxide
AYJ59_05150	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AYJ59_05155	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AYJ59_05160	COG0321	lipoyl(octanoyl) transferase activity
AYJ59_05165	COG2921	Belongs to the UPF0250 family
AYJ59_05175	COG1686	Belongs to the peptidase S11 family
AYJ59_05180	COG0772	Belongs to the SEDS family
AYJ59_05185	COG0768	penicillin binding
AYJ59_05200	COG1077	Cell shape determining protein MreB Mrl
AYJ59_05205	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AYJ59_05210	COG0154	amidase activity
AYJ59_05215	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AYJ59_05220	COG0501	Belongs to the peptidase M48B family
AYJ59_05230	COG2166	iron-sulfur cluster assembly
AYJ59_05240	COG0848	biopolymer transport protein
AYJ59_05245	COG0811	peptide transport
AYJ59_05250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYJ59_05255	COG0560	Phosphoserine phosphatase
AYJ59_05275	COG0517	IMP dehydrogenase activity
AYJ59_05275	COG0516	GMP reductase activity
AYJ59_05280	COG0519	Catalyzes the synthesis of GMP from XMP
AYJ59_05280	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AYJ59_05285	COG0590	tRNA wobble adenosine to inosine editing
AYJ59_05290	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AYJ59_05295	COG2198	Histidine kinase
AYJ59_05295	COG0643	Histidine kinase
AYJ59_05310	COG0326	Molecular chaperone. Has ATPase activity
AYJ59_05315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AYJ59_05320	COG0488	(ABC) transporter
AYJ59_05335	COG0438	transferase activity, transferring glycosyl groups
AYJ59_05345	COG0438	transferase activity, transferring glycosyl groups
AYJ59_05355	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AYJ59_05360	COG0189	ligase activity
AYJ59_05370	COG3118	belongs to the thioredoxin family
AYJ59_05375	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AYJ59_05385	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AYJ59_05390	COG2137	regulation of response to DNA damage stimulus
AYJ59_05395	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AYJ59_05405	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AYJ59_05425	COG0668	transmembrane transport
AYJ59_05430	COG0205	6-phosphofructokinase activity
AYJ59_05435	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AYJ59_05440	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AYJ59_05450	COG3101	peptidyl-lysine hydroxylation
AYJ59_05455	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AYJ59_05465	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AYJ59_05495	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AYJ59_05505	COG3079	Belongs to the UPF0149 family
AYJ59_05510	COG0006	proline dipeptidase activity
AYJ59_05515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYJ59_05520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AYJ59_05525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AYJ59_05530	COG0583	DNA-binding transcription factor activity
AYJ59_05535	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AYJ59_05540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AYJ59_05545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AYJ59_05555	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AYJ59_05555	COG0047	phosphoribosylformylglycinamidine synthase activity
AYJ59_05565	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AYJ59_05570	COG0521	Mo-molybdopterin cofactor biosynthetic process
AYJ59_05595	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AYJ59_05600	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AYJ59_05605	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
AYJ59_05615	COG0667	Aldo Keto reductase
AYJ59_05635	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AYJ59_05665	COG3123	guanosine phosphorylase activity
AYJ59_05670	COG0659	secondary active sulfate transmembrane transporter activity
AYJ59_05680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AYJ59_05685	COG0180	Tryptophanyl-tRNA synthetase
AYJ59_05690	COG0617	tRNA 3'-terminal CCA addition
AYJ59_05700	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AYJ59_05705	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AYJ59_05710	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AYJ59_05720	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AYJ59_05725	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AYJ59_05735	COG1132	(ABC) transporter
AYJ59_05745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYJ59_05750	COG0859	PFAM glycosyl transferase family 9
AYJ59_05775	COG0438	transferase activity, transferring glycosyl groups
AYJ59_05785	COG0859	PFAM glycosyl transferase family 9
AYJ59_05805	COG0424	maF-like protein
AYJ59_05810	COG1530	ribonuclease E activity
AYJ59_05855	COG0525	valine-tRNA ligase activity
AYJ59_05860	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AYJ59_05870	COG0004	ammonium transporteR
AYJ59_05885	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AYJ59_05890	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AYJ59_05895	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AYJ59_05905	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AYJ59_05905	COG0301	tRNA thio-modification
AYJ59_05910	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AYJ59_05915	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYJ59_05920	COG0557	exoribonuclease II activity
AYJ59_05925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AYJ59_05940	COG2885	chlorophyll binding
AYJ59_05945	COG0308	aminopeptidase N
AYJ59_05990	COG0784	Response regulator, receiver
AYJ59_05990	COG0835	chemotaxis
AYJ59_06000	COG1815	bacterial-type flagellum-dependent cell motility
AYJ59_06005	COG1558	bacterial-type flagellum-dependent cell motility
AYJ59_06010	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
AYJ59_06015	COG1749	Flagellar hook protein flgE
AYJ59_06020	COG4787	bacterial-type flagellum-dependent cell motility
AYJ59_06025	COG4786	Flagellar basal body rod
AYJ59_06030	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AYJ59_06035	COG1706	bacterial-type flagellum-dependent cell motility
AYJ59_06045	COG1256	bacterial-type flagellum assembly
AYJ59_06060	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AYJ59_06075	COG2089	acid synthase
AYJ59_06080	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AYJ59_06100	COG0107	imidazoleglycerol-phosphate synthase activity
AYJ59_06125	COG1083	cytidylyl-transferase
AYJ59_06130	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AYJ59_06145	COG1334	flagellar protein FlaG
AYJ59_06150	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AYJ59_06160	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AYJ59_06165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AYJ59_06175	COG1516	flagellar protein fliS
AYJ59_06190	COG3852	Histidine kinase
AYJ59_06195	COG2204	response regulator
AYJ59_06200	COG1677	Flagellar hook-basal body complex protein FliE
AYJ59_06210	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AYJ59_06240	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AYJ59_06245	COG1360	Flagellar Motor Protein
AYJ59_06275	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AYJ59_06295	COG0735	belongs to the Fur family
AYJ59_06300	COG3300	MHYT domain
AYJ59_06300	COG5001	Diguanylate cyclase
AYJ59_06305	COG0488	(ABC) transporter
AYJ59_06310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AYJ59_06315	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AYJ59_06320	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYJ59_06320	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AYJ59_06335	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AYJ59_06340	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AYJ59_06345	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AYJ59_06350	COG0840	transmembrane signaling receptor activity
AYJ59_06355	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AYJ59_06365	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AYJ59_06375	COG0720	synthase
AYJ59_06380	COG0142	geranyltranstransferase activity
AYJ59_06385	COG0450	alkyl hydroperoxide reductase
AYJ59_06400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AYJ59_06415	COG2197	response regulator
AYJ59_06445	COG3706	GGDEF domain
AYJ59_06450	COG1047	Peptidyl-prolyl cis-trans
AYJ59_06460	COG0045	succinate-CoA ligase (ADP-forming) activity
AYJ59_06465	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AYJ59_06480	COG0564	pseudouridine synthase activity
AYJ59_06500	COG3023	N-Acetylmuramoyl-L-alanine amidase
AYJ59_06510	COG0716	FMN binding
AYJ59_06515	COG0360	Binds together with S18 to 16S ribosomal RNA
AYJ59_06520	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AYJ59_06530	COG0359	binds to the 23S rRNA
AYJ59_06535	COG0305	Participates in initiation and elongation during chromosome replication
AYJ59_06545	COG0494	nUDIX hydrolase
AYJ59_06555	COG0534	Mate efflux family protein
AYJ59_06560	COG3012	SEC-C Motif Domain Protein
AYJ59_06595	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AYJ59_06610	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AYJ59_06615	COG0343	queuine tRNA-ribosyltransferase activity
AYJ59_06620	COG1862	Preprotein translocase
AYJ59_06625	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AYJ59_06630	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AYJ59_06640	COG0564	pseudouridine synthase activity
AYJ59_06645	COG2983	Belongs to the UPF0260 family
AYJ59_06650	COG1047	Peptidyl-prolyl cis-trans
AYJ59_06665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AYJ59_06670	COG0450	alkyl hydroperoxide reductase
AYJ59_06690	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AYJ59_06735	COG3647	Membrane
AYJ59_06750	COG0601	transmembrane transport
AYJ59_06765	COG1472	Belongs to the glycosyl hydrolase 3 family
AYJ59_06770	COG0668	transmembrane transport
AYJ59_06775	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AYJ59_06780	COG0733	neurotransmitter:sodium symporter activity
AYJ59_06795	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AYJ59_06800	COG1393	Belongs to the ArsC family
AYJ59_06805	COG2171	N-acyltransferase activity
AYJ59_06810	COG0346	lactoylglutathione lyase activity
AYJ59_06815	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AYJ59_06820	COG0024	Methionine aminopeptidase
AYJ59_06825	COG0052	Belongs to the universal ribosomal protein uS2 family
AYJ59_06830	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AYJ59_06835	COG0528	UMP kinase activity
AYJ59_06840	COG0233	cytoplasmic translational termination
AYJ59_06850	COG0575	Belongs to the CDS family
AYJ59_06855	COG0750	zinc metalloprotease
AYJ59_06870	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYJ59_06875	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AYJ59_06880	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYJ59_06885	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYJ59_06890	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AYJ59_06895	COG0835	chemotaxis
AYJ59_06895	COG0784	Response regulator, receiver
AYJ59_06900	COG1199	ATP-dependent helicase activity
AYJ59_06905	COG1214	PFAM Peptidase M22, glycoprotease
AYJ59_06920	COG1944	ATP diphosphatase activity
AYJ59_06925	COG0825	malonyl-CoA metabolic process
AYJ59_06930	COG0037	tRNA processing
AYJ59_06935	COG0504	CTP synthase activity
AYJ59_06940	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AYJ59_06945	COG0148	phosphopyruvate hydratase activity
AYJ59_06955	COG2840	Smr protein MutS2
AYJ59_06960	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AYJ59_06965	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AYJ59_06970	COG1238	metal cluster binding
AYJ59_06975	COG4942	peptidase
AYJ59_06985	COG0436	Aminotransferase
AYJ59_07000	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AYJ59_07010	COG3150	esterase
AYJ59_07030	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AYJ59_07035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AYJ59_07040	COG1070	Carbohydrate kinase
AYJ59_07050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AYJ59_07055	COG3028	Belongs to the UPF0307 family
AYJ59_07060	COG0697	spore germination
AYJ59_07065	COG0252	asparaginase activity
AYJ59_07070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AYJ59_07075	COG2350	Protein conserved in bacteria
AYJ59_07080	COG2917	probably involved in intracellular septation
AYJ59_07085	COG0613	PHP domain protein
AYJ59_07090	COG0009	L-threonylcarbamoyladenylate synthase
AYJ59_07095	COG1994	Peptidase M50
AYJ59_07100	COG1187	pseudouridine synthase activity
AYJ59_07120	COG0330	HflC and HflK could
AYJ59_07170	COG0069	glutamate synthase activity
AYJ59_07175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AYJ59_07205	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AYJ59_07210	COG0363	glucosamine-6-phosphate deaminase activity
AYJ59_07215	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AYJ59_07225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYJ59_07230	COG1570	exodeoxyribonuclease VII activity
AYJ59_07240	COG1393	Belongs to the ArsC family
AYJ59_07250	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AYJ59_07275	COG0284	orotidine-5'-phosphate decarboxylase activity
AYJ59_07285	COG0776	regulation of translation
AYJ59_07290	COG0539	negative regulation of cytoplasmic translation
AYJ59_07295	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AYJ59_07300	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AYJ59_07305	COG0287	Prephenate dehydrogenase
AYJ59_07310	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AYJ59_07320	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AYJ59_07330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AYJ59_07340	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ59_07350	COG0574	Belongs to the PEP-utilizing enzyme family
AYJ59_07350	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AYJ59_07355	COG4172	Belongs to the ABC transporter superfamily
AYJ59_07360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AYJ59_07365	COG0601	transmembrane transport
AYJ59_07370	COG0747	negative chemotaxis
AYJ59_07405	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AYJ59_07410	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AYJ59_07415	COG0740	serine-type endopeptidase activity
AYJ59_07420	COG0544	peptidyl-prolyl cis-trans isomerase activity
AYJ59_07430	COG0488	(ABC) transporter
AYJ59_07435	COG1136	(ABC) transporter
AYJ59_07440	COG4591	ABC-type transport system involved in lipoprotein release permease component
AYJ59_07450	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYJ59_07460	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AYJ59_07470	COG2814	Major facilitator Superfamily
AYJ59_07475	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AYJ59_07480	COG2894	cell division
AYJ59_07485	COG0850	regulation of cytokinetic process
AYJ59_07505	COG0732	type I restriction modification DNA specificity domain
AYJ59_07535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AYJ59_07540	COG0322	excinuclease ABC activity
AYJ59_07550	COG3706	GGDEF domain
AYJ59_07550	COG0745	RESPONSE REGULATOR receiver
AYJ59_07580	COG1970	mechanosensitive ion channel activity
AYJ59_07590	COG1192	Involved in chromosome partitioning
AYJ59_07605	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AYJ59_07635	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AYJ59_07655	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AYJ59_07685	COG2850	peptidyl-arginine hydroxylation
AYJ59_07705	COG1185	polyribonucleotide nucleotidyltransferase activity
AYJ59_07710	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AYJ59_07720	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AYJ59_07725	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AYJ59_07730	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AYJ59_07735	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AYJ59_07740	COG2251	uridine kinase activity
AYJ59_07740	COG0195	Participates in both transcription termination and antitermination
AYJ59_07745	COG0779	Required for maturation of 30S ribosomal subunits
AYJ59_07760	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AYJ59_07765	COG3162	membrane
AYJ59_07770	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AYJ59_07775	COG0587	DNA-directed DNA polymerase activity
AYJ59_07780	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AYJ59_07785	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AYJ59_07790	COG0542	response to heat
AYJ59_07795	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AYJ59_07805	COG2824	Alkylphosphonate utilization operon protein PhnA
AYJ59_07810	COG3706	GGDEF domain
AYJ59_07810	COG0745	RESPONSE REGULATOR receiver
AYJ59_07815	COG0217	transcriptional regulatory protein
AYJ59_07830	COG1187	pseudouridine synthase activity
AYJ59_07835	COG0482	sulfurtransferase activity
AYJ59_07840	COG2915	High frequency lysogenization protein hflD homolog
AYJ59_07850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AYJ59_07860	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AYJ59_07865	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AYJ59_07875	COG0330	HflC and HflK could
AYJ59_07880	COG0330	HflC and HflK could
AYJ59_07885	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AYJ59_07890	COG1923	regulation of RNA biosynthetic process
AYJ59_07895	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AYJ59_07900	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AYJ59_07905	COG0860	N-Acetylmuramoyl-L-alanine amidase
AYJ59_07910	COG0802	atpase or kinase
AYJ59_07925	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AYJ59_07950	COG0442	prolyl-tRNA aminoacylation
AYJ59_07955	COG1280	lysine exporter protein (LysE YggA)
AYJ59_07960	COG2194	sulfuric ester hydrolase activity
AYJ59_07965	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AYJ59_07970	COG1733	regulation of RNA biosynthetic process
AYJ59_07975	COG0778	Nitroreductase
AYJ59_07980	COG1278	Cold shock
AYJ59_08000	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
AYJ59_08005	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AYJ59_08025	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AYJ59_08030	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AYJ59_08040	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AYJ59_08045	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AYJ59_08055	COG0717	Belongs to the dCTP deaminase family
AYJ59_08060	COG0489	protein tyrosine kinase activity
AYJ59_08065	COG4191	Histidine kinase
AYJ59_08070	COG2204	response regulator
AYJ59_08085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYJ59_08085	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AYJ59_08090	COG4657	Part of a membrane complex involved in electron transport
AYJ59_08095	COG2878	Part of a membrane complex involved in electron transport
AYJ59_08105	COG4658	electron transport chain
AYJ59_08115	COG4660	Part of a membrane complex involved in electron transport
AYJ59_08120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AYJ59_08150	COG0545	Peptidyl-prolyl cis-trans isomerase
AYJ59_08180	COG0778	Nitroreductase
AYJ59_08200	COG1902	pentaerythritol trinitrate reductase activity
AYJ59_08210	COG3530	Putative quorum-sensing-regulated virulence factor
AYJ59_08220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AYJ59_08225	COG0508	dehydrogenase complex catalyzes the overall conversion of
AYJ59_08230	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AYJ59_08235	COG1051	belongs to the nudix hydrolase family
AYJ59_08250	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AYJ59_08255	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AYJ59_08260	COG4536	flavin adenine dinucleotide binding
AYJ59_08270	COG2198	Histidine kinase
AYJ59_08270	COG5002	protein histidine kinase activity
AYJ59_08270	COG0784	Response regulator, receiver
AYJ59_08275	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AYJ59_08280	COG2857	Cytochrome c1
AYJ59_08285	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AYJ59_08290	COG0723	plastoquinol--plastocyanin reductase activity
AYJ59_08295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AYJ59_08300	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AYJ59_08305	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AYJ59_08310	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AYJ59_08320	COG0842	Transport permease protein
AYJ59_08325	COG1131	(ABC) transporter
AYJ59_08340	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AYJ59_08345	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AYJ59_08350	COG1127	ABC transporter
AYJ59_08375	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AYJ59_08380	COG1137	ATPase activity
AYJ59_08390	COG2239	Acts as a magnesium transporter
AYJ59_08395	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AYJ59_08400	COG0745	RESPONSE REGULATOR receiver
AYJ59_08405	COG2205	protein histidine kinase activity
AYJ59_08410	COG3038	cytochrome b561
AYJ59_08425	COG2210	Belongs to the sulfur carrier protein TusA family
AYJ59_08430	COG4206	TonB-dependent receptor
AYJ59_08435	COG1492	cobalamin metabolic process
AYJ59_08445	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AYJ59_08455	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AYJ59_08460	COG2835	tetraacyldisaccharide 4'-kinase activity
AYJ59_08465	COG1663	tetraacyldisaccharide 4'-kinase activity
AYJ59_08470	COG0658	competence protein
AYJ59_08470	COG2333	competence protein COMEC
AYJ59_08480	COG1067	ATP-dependent peptidase activity
AYJ59_08485	COG0004	ammonium transporteR
AYJ59_08505	COG4251	negative regulation of phosphorylation
AYJ59_08505	COG5001	Diguanylate cyclase
AYJ59_08505	COG2203	Gaf domain
AYJ59_08505	COG3706	GGDEF domain
AYJ59_08515	COG1643	Atp-dependent helicase
AYJ59_08525	COG3655	Transcriptional regulator
AYJ59_08545	COG0330	HflC and HflK could
AYJ59_08570	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ59_08600	COG2249	NAD(P)H dehydrogenase (quinone) activity
AYJ59_08655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AYJ59_08660	COG0038	chloride channel
AYJ59_08665	COG2271	Major facilitator Superfamily
AYJ59_08685	COG1047	Peptidyl-prolyl cis-trans
AYJ59_08690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYJ59_08700	COG0328	RNA-DNA hybrid ribonuclease activity
AYJ59_08710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AYJ59_08715	COG1388	LysM domain
AYJ59_08715	COG0741	lytic transglycosylase activity
AYJ59_08725	COG0215	cysteine-tRNA ligase activity
AYJ59_08730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AYJ59_08740	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AYJ59_08745	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AYJ59_08755	COG1301	dicarboxylic acid transport
AYJ59_08765	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AYJ59_08770	COG0137	argininosuccinate synthase activity
AYJ59_08775	COG0688	phosphatidylethanolamine metabolic process
AYJ59_08790	COG2204	response regulator
AYJ59_08795	COG3852	Histidine kinase
AYJ59_08825	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AYJ59_08840	COG0823	Involved in the tonB-independent uptake of proteins
AYJ59_08850	COG0848	biopolymer transport protein
AYJ59_08860	COG2255	four-way junction helicase activity
AYJ59_08870	COG0632	four-way junction helicase activity
AYJ59_08875	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AYJ59_08880	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AYJ59_08885	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AYJ59_08895	COG0300	oxidoreductase activity
AYJ59_08900	COG1752	Esterase of the alpha-beta hydrolase superfamily
AYJ59_08910	COG1940	carbohydrate kinase activity
AYJ59_08920	COG2833	Protein of unknown function (DUF455)
AYJ59_08935	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AYJ59_08945	COG0505	Belongs to the CarA family
AYJ59_08955	COG2814	Major facilitator Superfamily
AYJ59_08970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AYJ59_08985	COG0840	transmembrane signaling receptor activity
AYJ59_08985	COG0840	transmembrane signaling receptor activity
AYJ59_08995	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AYJ59_09000	COG0484	heat shock protein binding
AYJ59_09005	COG0443	Heat shock 70 kDa protein
AYJ59_09010	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AYJ59_09015	COG1420	regulation of RNA biosynthetic process
AYJ59_09020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AYJ59_09025	COG0497	DNA recombination
AYJ59_09045	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AYJ59_09065	COG5002	protein histidine kinase activity
AYJ59_09065	COG2205	protein histidine kinase activity
AYJ59_09065	COG0784	Response regulator, receiver
AYJ59_09070	COG3437	response regulator, receiver
AYJ59_09085	COG2771	luxR family
AYJ59_09085	COG2200	EAL domain
AYJ59_09095	COG1007	ATP synthesis coupled electron transport
AYJ59_09110	COG0713	ATP synthesis coupled electron transport
AYJ59_09120	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYJ59_09125	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AYJ59_09130	COG1034	ATP synthesis coupled electron transport
AYJ59_09145	COG0649	NAD binding
AYJ59_09150	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYJ59_09155	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYJ59_09160	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AYJ59_09175	COG0149	triose-phosphate isomerase activity
AYJ59_09180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AYJ59_09185	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AYJ59_09190	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AYJ59_09195	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AYJ59_09200	COG1534	Rna-binding protein
AYJ59_09220	COG0285	dihydrofolate synthase activity
AYJ59_09225	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AYJ59_09230	COG0159	tryptophan synthase activity
AYJ59_09235	COG0133	tryptophan synthase activity
AYJ59_09240	COG0135	phosphoribosylanthranilate isomerase activity
AYJ59_09245	COG0101	tRNA pseudouridine synthase activity
AYJ59_09250	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AYJ59_09260	COG0739	heme binding
AYJ59_09265	COG0473	3-isopropylmalate dehydrogenase activity
AYJ59_09270	COG0066	3-isopropylmalate dehydratase activity
AYJ59_09275	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AYJ59_09280	COG0602	queuosine metabolic process
AYJ59_09300	COG0446	pyridine nucleotide-disulphide oxidoreductase
AYJ59_09305	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AYJ59_09310	COG3384	dioxygenase
AYJ59_09325	COG3706	GGDEF domain
AYJ59_09330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AYJ59_09335	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AYJ59_09340	COG1090	epimerase
AYJ59_09345	COG0583	DNA-binding transcription factor activity
AYJ59_09350	COG3038	cytochrome b561
AYJ59_09360	COG0513	Belongs to the DEAD box helicase family
AYJ59_09365	COG0840	transmembrane signaling receptor activity
AYJ59_09370	COG0840	transmembrane signaling receptor activity
AYJ59_09380	COG5002	protein histidine kinase activity
AYJ59_09380	COG5001	Diguanylate cyclase
AYJ59_09385	COG4191	Histidine kinase
AYJ59_09390	COG4566	intracellular signal transduction
AYJ59_09400	COG0577	efflux transmembrane transporter activity
AYJ59_09400	COG1136	(ABC) transporter
AYJ59_09405	COG1136	(ABC) transporter
AYJ59_09405	COG0577	efflux transmembrane transporter activity
AYJ59_09410	COG1566	PFAM secretion protein HlyD family protein
AYJ59_09420	COG5002	protein histidine kinase activity
AYJ59_09430	COG1929	Belongs to the glycerate kinase type-1 family
AYJ59_09445	COG2308	Evidence 4 Homologs of previously reported genes of
AYJ59_09455	COG1215	transferase activity, transferring glycosyl groups
AYJ59_09460	COG3769	mannosylglycerate metabolic process
AYJ59_09470	COG2200	EAL domain
AYJ59_09470	COG2199	diguanylate cyclase activity
AYJ59_09495	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AYJ59_09500	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AYJ59_09505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AYJ59_09510	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AYJ59_09515	COG1674	ftsk spoiiie
AYJ59_09520	COG0492	ferredoxin-NADP+ reductase activity
AYJ59_09525	COG0545	Peptidyl-prolyl cis-trans isomerase
AYJ59_09530	COG3323	Protein of unknown function (DUF1653)
AYJ59_09530	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AYJ59_09545	COG2201	protein-glutamate methylesterase activity
AYJ59_09560	COG0835	chemotaxis
AYJ59_09565	COG0745	RESPONSE REGULATOR receiver
AYJ59_09580	COG0835	chemotaxis
AYJ59_09585	COG2198	Histidine kinase
AYJ59_09585	COG0643	Histidine kinase
AYJ59_09590	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
AYJ59_09605	COG0455	bacterial-type flagellum organization
AYJ59_09630	COG1987	bacterial-type flagellum assembly
AYJ59_09645	COG0736	holo-[acyl-carrier-protein] synthase activity
AYJ59_09650	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AYJ59_09655	COG1381	Involved in DNA repair and RecF pathway recombination
AYJ59_09660	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AYJ59_09675	COG0481	GTPase activity
AYJ59_09680	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AYJ59_09690	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AYJ59_09695	COG0835	chemotaxis
AYJ59_09700	COG0354	folic acid binding
AYJ59_09705	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AYJ59_09715	COG1064	alcohol dehydrogenase
AYJ59_09730	COG2207	Transcriptional regulator
AYJ59_09735	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AYJ59_09755	COG0840	transmembrane signaling receptor activity
AYJ59_09760	COG1132	(ABC) transporter
AYJ59_09765	COG0084	hydrolase, TatD family'
AYJ59_09770	COG0470	DNA polymerase III
AYJ59_09775	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AYJ59_09780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AYJ59_09790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AYJ59_09800	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AYJ59_09810	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AYJ59_09815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AYJ59_09820	COG0416	fatty acid biosynthetic process
AYJ59_09825	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AYJ59_09835	COG0424	maF-like protein
AYJ59_09840	COG0546	phosphoglycolate phosphatase activity
AYJ59_09845	COG0564	pseudouridine synthase activity
AYJ59_09850	COG1530	ribonuclease E activity
AYJ59_09855	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AYJ59_09860	COG0564	pseudouridine synthase activity
AYJ59_09875	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AYJ59_09880	COG4974	Belongs to the 'phage' integrase family
AYJ59_09885	COG0335	large ribosomal subunit rRNA binding
AYJ59_09890	COG0336	Belongs to the RNA methyltransferase TrmD family
AYJ59_09895	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AYJ59_09900	COG0228	four-way junction DNA binding
AYJ59_09905	COG0745	RESPONSE REGULATOR receiver
AYJ59_09910	COG1322	Protein conserved in bacteria
AYJ59_09930	COG1459	type II secretion system
AYJ59_09935	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AYJ59_09950	COG3409	Peptidoglycan-binding domain 1 protein
AYJ59_09950	COG3267	Type II secretory pathway component ExeA
AYJ59_09960	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AYJ59_09965	COG0440	acetolactate synthase activity
AYJ59_09970	COG0028	Belongs to the TPP enzyme family
AYJ59_09975	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AYJ59_09980	COG0501	Belongs to the peptidase M48B family
AYJ59_09985	COG2154	pterin-4-alpha-carbinolamine dehydratase
AYJ59_09990	COG1162	GTPase activity
AYJ59_09995	COG3842	ATPase activity
AYJ59_10005	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AYJ59_10020	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYJ59_10025	COG0247	lactate metabolic process
AYJ59_10025	COG0277	FAD linked oxidase domain protein
AYJ59_10030	COG1160	GTP binding
AYJ59_10035	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AYJ59_10045	COG0124	histidyl-tRNA synthetase
AYJ59_10055	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AYJ59_10060	COG0105	UTP biosynthetic process
AYJ59_10065	COG0316	Belongs to the HesB IscA family
AYJ59_10100	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AYJ59_10105	COG1183	phosphatidylcholine synthase activity
AYJ59_10115	COG0166	Belongs to the GPI family
AYJ59_10120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AYJ59_10130	COG4783	chaperone-mediated protein folding
AYJ59_10150	COG3258	Cytochrome c
AYJ59_10160	COG0129	dihydroxy-acid dehydratase activity
AYJ59_10165	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AYJ59_10165	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AYJ59_10170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AYJ59_10175	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AYJ59_10180	COG0367	asparagine synthase
AYJ59_10185	COG0237	dephospho-CoA kinase activity
AYJ59_10195	COG0352	thiamine-phosphate diphosphorylase activity
AYJ59_10200	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AYJ59_10205	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AYJ59_10210	COG0653	protein targeting
AYJ59_10215	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AYJ59_10230	COG1181	Belongs to the D-alanine--D-alanine ligase family
AYJ59_10235	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AYJ59_10245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AYJ59_10250	COG0719	Fe-S assembly protein
AYJ59_10255	COG0396	ATPase activity
AYJ59_10260	COG0719	Fe-S assembly protein
AYJ59_10275	COG1121	(ABC) transporter
AYJ59_10280	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AYJ59_10285	COG0840	transmembrane signaling receptor activity
AYJ59_10295	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AYJ59_10300	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AYJ59_10310	COG1028	Short-chain dehydrogenase reductase Sdr
AYJ59_10315	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AYJ59_10320	COG0772	Belongs to the SEDS family
AYJ59_10325	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AYJ59_10330	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AYJ59_10335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AYJ59_10340	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AYJ59_10360	COG0275	rRNA processing
AYJ59_10365	COG2001	Belongs to the MraZ family
AYJ59_10395	COG1643	Atp-dependent helicase
AYJ59_10400	COG0840	transmembrane signaling receptor activity
AYJ59_10415	COG3706	GGDEF domain
AYJ59_10425	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AYJ59_10430	COG4181	ATPase activity
AYJ59_10435	COG2755	lipolytic protein G-D-S-L family
AYJ59_10470	COG0306	phosphate transporter
AYJ59_10490	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AYJ59_10495	COG0573	inorganic phosphate transmembrane transporter activity
AYJ59_10505	COG0174	glutamine synthetase
AYJ59_10520	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AYJ59_10525	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AYJ59_10530	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AYJ59_10535	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AYJ59_10540	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AYJ59_10555	COG1252	NADH dehydrogenase
AYJ59_10565	COG1566	PFAM secretion protein HlyD family protein
AYJ59_10585	COG0527	aspartate kinase activity
AYJ59_10590	COG1917	Cupin 2, conserved barrel domain protein
AYJ59_10595	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AYJ59_10625	COG0058	SHG alpha-glucan phosphorylase activity
AYJ59_10630	COG0297	glycogen (starch) synthase activity
AYJ59_10635	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AYJ59_10650	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AYJ59_10655	COG0837	glucose binding
AYJ59_10660	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AYJ59_10665	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AYJ59_10665	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AYJ59_10675	COG0517	IMP dehydrogenase activity
AYJ59_10675	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AYJ59_10680	COG1519	Transferase
AYJ59_10695	COG0116	Belongs to the methyltransferase superfamily
AYJ59_10695	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AYJ59_10700	COG2951	lytic endotransglycosylase activity
AYJ59_10705	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AYJ59_10710	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AYJ59_10715	COG0196	riboflavin kinase activity
AYJ59_10725	COG0268	Binds directly to 16S ribosomal RNA
AYJ59_10770	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AYJ59_10775	COG0799	negative regulation of ribosome biogenesis
AYJ59_10780	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AYJ59_10790	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AYJ59_10805	COG0495	leucyl-tRNA aminoacylation
AYJ59_10815	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AYJ59_10820	COG4535	Mg2 and Co2 transporter CorC
AYJ59_10825	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AYJ59_10830	COG1702	phosphate starvation-inducible protein PhoH
AYJ59_10835	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AYJ59_10845	COG4191	Histidine kinase
AYJ59_10850	COG2204	response regulator
AYJ59_10855	COG2165	general secretion pathway protein
AYJ59_10885	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AYJ59_10890	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AYJ59_10895	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AYJ59_10915	COG0745	RESPONSE REGULATOR receiver
AYJ59_10915	COG3706	GGDEF domain
AYJ59_10920	COG0523	cobalamin synthesis protein
AYJ59_10945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AYJ59_10950	COG3439	Domain of unknown function DUF302
AYJ59_10955	COG2067	long-chain fatty acid transport protein
AYJ59_10970	COG4232	protein-disulfide reductase activity
AYJ59_10975	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AYJ59_10980	COG0511	ligase activity, forming carbon-carbon bonds
AYJ59_10985	COG0439	Biotin carboxylase
AYJ59_10990	COG2264	protein methyltransferase activity
AYJ59_10995	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AYJ59_11000	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AYJ59_11005	COG0138	bifunctional purine biosynthesis protein purh
AYJ59_11025	COG4548	von Willebrand factor, type A
AYJ59_11040	COG1850	ribulose-bisphosphate carboxylase activity
AYJ59_11045	COG0583	DNA-binding transcription factor activity
AYJ59_11050	COG0583	DNA-binding transcription factor activity
AYJ59_11075	COG0288	reversible hydration of carbon dioxide
AYJ59_11090	COG0542	response to heat
AYJ59_11095	COG3706	GGDEF domain
AYJ59_11105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AYJ59_11115	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AYJ59_11120	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AYJ59_11125	COG3706	GGDEF domain
AYJ59_11135	COG2095	MarC family integral membrane protein
AYJ59_11140	COG3447	MASE1 domain protein
AYJ59_11140	COG5002	protein histidine kinase activity
AYJ59_11140	COG5001	Diguanylate cyclase
AYJ59_11145	COG2932	Transcriptional regulator
AYJ59_11155	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AYJ59_11160	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AYJ59_11170	COG2226	methyltransferase
AYJ59_11180	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AYJ59_11185	COG2252	PERMEase
AYJ59_11215	COG4771	TonB-dependent receptor
AYJ59_11235	COG3550	peptidyl-serine autophosphorylation
AYJ59_11270	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AYJ59_11305	COG0012	GTP binding
AYJ59_11310	COG0193	aminoacyl-tRNA hydrolase activity
AYJ59_11315	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AYJ59_11320	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AYJ59_11335	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AYJ59_11340	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AYJ59_11345	COG2890	protein-(glutamine-N5) methyltransferase activity
AYJ59_11350	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AYJ59_11360	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AYJ59_11370	COG2608	mercury ion transmembrane transporter activity
AYJ59_11390	COG3706	GGDEF domain
AYJ59_11400	COG0259	pyridoxamine-phosphate oxidase activity
AYJ59_11405	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AYJ59_11435	COG0751	glycine-tRNA ligase activity
AYJ59_11445	COG0425	Belongs to the sulfur carrier protein TusA family
AYJ59_11450	COG0739	heme binding
AYJ59_11455	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AYJ59_11465	COG0316	Belongs to the HesB IscA family
AYJ59_11470	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AYJ59_11475	COG0459	protein refolding
AYJ59_11480	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AYJ59_11485	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AYJ59_11490	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AYJ59_11495	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AYJ59_11500	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AYJ59_11505	COG0142	geranyltranstransferase activity
AYJ59_11555	COG2814	Major facilitator Superfamily
AYJ59_11575	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AYJ59_11585	COG0203	ribosomal protein L17
AYJ59_11590	COG0202	RNA polymerase activity
AYJ59_11595	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AYJ59_11600	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AYJ59_11605	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AYJ59_11610	COG0201	protein transport
AYJ59_11615	COG0200	Binds to the 23S rRNA
AYJ59_11620	COG1841	ribosomal large subunit assembly
AYJ59_11625	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AYJ59_11630	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AYJ59_11635	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AYJ59_11640	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AYJ59_11645	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AYJ59_11650	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AYJ59_11655	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AYJ59_11660	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AYJ59_11665	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AYJ59_11670	COG0255	Belongs to the universal ribosomal protein uL29 family
AYJ59_11675	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AYJ59_11680	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AYJ59_11685	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AYJ59_11690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AYJ59_11695	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AYJ59_11700	COG0089	rRNA binding
AYJ59_11705	COG0088	Forms part of the polypeptide exit tunnel
AYJ59_11710	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AYJ59_11715	COG0051	transcription antitermination factor activity, RNA binding
AYJ59_11720	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AYJ59_11725	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AYJ59_11730	COG0049	tRNA binding
AYJ59_11735	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AYJ59_11740	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AYJ59_11745	COG0085	RNA polymerase activity
AYJ59_11750	COG0222	ribosome binding
AYJ59_11755	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AYJ59_11760	COG0081	regulation of translation
AYJ59_11765	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AYJ59_11775	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AYJ59_11785	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AYJ59_11815	COG0564	pseudouridine synthase activity
AYJ59_11820	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AYJ59_11830	COG1765	OsmC-like protein
AYJ59_11840	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AYJ59_11845	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AYJ59_11850	COG0134	indole-3-glycerol-phosphate synthase activity
AYJ59_11855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AYJ59_11860	COG0512	Glutamine amidotransferase of anthranilate synthase
AYJ59_11870	COG0546	phosphoglycolate phosphatase activity
AYJ59_11875	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AYJ59_11885	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AYJ59_11890	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
AYJ59_11910	COG0126	phosphoglycerate kinase activity
AYJ59_11915	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AYJ59_11920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AYJ59_11945	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AYJ59_11950	COG0617	tRNA 3'-terminal CCA addition
AYJ59_11960	COG3100	YcgL domain-containing protein
AYJ59_11995	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AYJ59_12015	COG2020	methyltransferase activity
AYJ59_12020	COG2133	pyrroloquinoline quinone binding
AYJ59_12025	COG1238	metal cluster binding
AYJ59_12045	COG1012	belongs to the aldehyde dehydrogenase family
AYJ59_12050	COG0006	proline dipeptidase activity
AYJ59_12055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AYJ59_12060	COG1473	amidohydrolase
AYJ59_12070	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AYJ59_12075	COG0585	pseudouridine synthase activity
AYJ59_12090	COG2813	Specifically methylates the guanine in position
AYJ59_12100	COG1454	alcohol dehydrogenase
AYJ59_12115	COG2199	diguanylate cyclase activity
AYJ59_12115	COG3287	FIST C domain
AYJ59_12115	COG2200	EAL domain
AYJ59_12130	COG2197	response regulator
AYJ59_12145	COG0606	chelatase, subunit chli
AYJ59_12210	COG0745	RESPONSE REGULATOR receiver
AYJ59_12210	COG3706	GGDEF domain
AYJ59_12220	COG0018	arginyl-trna synthetase
AYJ59_12225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AYJ59_12225	COG1754	DNA topoisomerase type I activity
AYJ59_12230	COG0745	RESPONSE REGULATOR receiver
AYJ59_12235	COG0758	DNA mediated transformation
AYJ59_12240	COG0242	peptide deformylase activity
AYJ59_12245	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AYJ59_12260	COG5000	phosphorelay sensor kinase activity
AYJ59_12265	COG2204	response regulator
AYJ59_12270	COG0569	domain protein
AYJ59_12275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AYJ59_12295	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AYJ59_12300	COG1560	Kdo2-lipid A biosynthetic process
AYJ59_12305	COG0037	tRNA processing
AYJ59_12310	COG2199	diguanylate cyclase activity
AYJ59_12310	COG2200	EAL domain
AYJ59_12310	COG3287	FIST C domain
AYJ59_12330	COG4771	TonB-dependent receptor
AYJ59_12335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AYJ59_12350	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AYJ59_12355	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AYJ59_12360	COG4558	Periplasmic binding protein
AYJ59_12365	COG3720	iron ion transport
AYJ59_12370	COG4206	TonB-dependent receptor
AYJ59_12380	COG1528	Iron-storage protein
AYJ59_12405	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AYJ59_12410	COG0745	RESPONSE REGULATOR receiver
AYJ59_12410	COG3706	GGDEF domain
AYJ59_12415	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AYJ59_12420	COG1410	methionine synthase
AYJ59_12420	COG0646	methionine synthase
AYJ59_12440	COG2239	Acts as a magnesium transporter
AYJ59_12460	COG3038	cytochrome b561
AYJ59_12465	COG2818	Glycosylase
AYJ59_12490	COG1490	D-aminoacyl-tRNA deacylase activity
AYJ59_12515	COG0315	cyclic pyranopterin monophosphate synthase activity
AYJ59_12520	COG0303	'Molybdopterin
AYJ59_12525	COG0314	molybdopterin synthase activity
AYJ59_12530	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AYJ59_12535	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AYJ59_12560	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AYJ59_12570	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AYJ59_12580	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AYJ59_12595	COG2022	thiamine diphosphate biosynthetic process
AYJ59_12600	COG0352	thiamine-phosphate diphosphorylase activity
AYJ59_12610	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AYJ59_12635	COG4774	siderophore transport
AYJ59_12660	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AYJ59_12660	COG0678	peroxiredoxin activity
AYJ59_12675	COG2081	HI0933 family
AYJ59_12685	COG0784	Response regulator, receiver
AYJ59_12685	COG5002	protein histidine kinase activity
AYJ59_12685	COG2205	protein histidine kinase activity
AYJ59_12705	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AYJ59_12705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AYJ59_12715	COG1136	(ABC) transporter
AYJ59_12720	COG0210	DNA helicase
AYJ59_12730	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AYJ59_12740	COG0254	rRNA binding
AYJ59_12750	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AYJ59_12760	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
AYJ59_12765	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AYJ59_12770	COG1194	a g-specific adenine glycosylase
AYJ59_12775	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AYJ59_12785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AYJ59_12790	COG0857	belongs to the CobB CobQ family
AYJ59_12790	COG0280	phosphate acetyltransferase
AYJ59_12805	COG1566	PFAM secretion protein HlyD family protein
AYJ59_12840	COG0181	hydroxymethylbilane synthase activity
AYJ59_12850	COG0165	Argininosuccinate lyase
AYJ59_12855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis