locus-tag	class	description
Tint_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Tint_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Tint_0003	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Tint_0005	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Tint_0006	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Tint_0007	ENOG4105CHC	glucokinase (EC 2.7.1.2)
Tint_0008	ENOG4105C01	Dihydroxy-acid dehydratase
Tint_0009	ENOG4108UHU	Aldolase
Tint_0012	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Tint_0013	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Tint_0015	ENOG4105PGM	cation diffusion facilitator family transporter
Tint_0020	ENOG4108JQC	penicillin-binding protein 1A
Tint_0021	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
Tint_0022	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
Tint_0023	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
Tint_0026	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Tint_0027	ENOG4108UYE	Lactoylglutathione lyase
Tint_0031	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
Tint_0032	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
Tint_0034	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
Tint_0036	ENOG41090R7	Ferric uptake
Tint_0037	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
Tint_0040	ENOG4105SG9	biopolymer transport protein, ExbD
Tint_0042	ENOG4105BZU	Histidine kinase
Tint_0043	ENOG4105C5X	domain protein
Tint_0048	ENOG4105KFG	YeeE YedE family protein
Tint_0049	ENOG4105MD1	YeeE YedE family protein
Tint_0051	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Tint_0053	ENOG4107WP9	Histidine kinase
Tint_0054	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Tint_0055	ENOG4105D6S	protein involved in catabolism of external DNA
Tint_0056	ENOG4105KWI	UPF0339 protein
Tint_0057	ENOG4107QN2	dihydrolipoyl dehydrogenase
Tint_0059	ENOG4108JJ8	(ABC) transporter
Tint_0060	ENOG4108JJ9	ABC, transporter
Tint_0065	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
Tint_0066	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
Tint_0067	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
Tint_0068	ENOG4105C08	Histidine kinase
Tint_0069	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
Tint_0071	ENOG4108UUM	single-stranded DNA-binding protein
Tint_0072	ENOG4107RDB	Major Facilitator
Tint_0075	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Tint_0076	ENOG4105DR5	peptidase
Tint_0077	ENOG4105DR5	peptidase
Tint_0078	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
Tint_0080	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Tint_0081	ENOG4105VIE	preprotein translocase, subunit YajC
Tint_0082	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Tint_0083	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Tint_0085	ENOG4108RPN	Protein smg homolog
Tint_0086	ENOG4105C79	DNA protecting protein DprA
Tint_0088	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Tint_0089	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Tint_0090	ENOG4105D0M	Protease HtpX homolog
Tint_0091	ENOG41086DT	Membrane protein of unknown function
Tint_0092	ENOG4107QTF	adenylosuccinate lyase
Tint_0093	ENOG4108U78	Glutathione S-transferase
Tint_0095	ENOG4108ZAI	phosphatidylglycerophosphatase a
Tint_0096	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
Tint_0097	ENOG4105C6K	Malic enzyme
Tint_0100	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Tint_0101	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
Tint_0102	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
Tint_0103	ENOG4105EHM	Aminoglycoside phosphotransferase
Tint_0104	ENOG4108S0S	Nucleotidyl transferase
Tint_0105	ENOG4107RAQ	aminopeptidase
Tint_0110	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
Tint_0121	ENOG4105KNY	Microcompartments protein
Tint_0122	ENOG4105KNY	Microcompartments protein
Tint_0123	ENOG4105KNY	Microcompartments protein
Tint_0124	ENOG4108UQY	Iron-storage protein
Tint_0126	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
Tint_0129	ENOG4105FAE	von Willebrand factor, type A
Tint_0133	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Tint_0134	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
Tint_0135	ENOG4105DUM	transcriptional regulator, lysR family
Tint_0136	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Tint_0137	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
Tint_0138	ENOG4105CV1	Transketolase (EC 2.2.1.1)
Tint_0139	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Tint_0140	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Tint_0141	ENOG4105BZA	Phosphoglycerate kinase
Tint_0142	ENOG4105D2N	Aldolase
Tint_0144	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
Tint_0146	ENOG4105DJF	DNA polymerase III, delta' subunit
Tint_0148	ENOG4105C8T	Leucyl-tRNA synthetase
Tint_0149	ENOG4105CEP	NADH dehydrogenase
Tint_0151	ENOG4105CI2	imidazolone-5-propionate hydrolase
Tint_0154	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Tint_0155	ENOG410829K	Lysine exporter protein (Lyse ygga)
Tint_0156	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Tint_0157	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Tint_0158	ENOG4105DFF	Rod shape-determining protein mreb
Tint_0159	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
Tint_0161	ENOG4105CJN	penicillin-binding protein
Tint_0162	ENOG4105CNI	cell division protein FtsW
Tint_0168	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Tint_0169	ENOG4105CYW	agmatinase
Tint_0170	ENOG4105CJP	fad dependent oxidoreductase
Tint_0171	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
Tint_0174	ENOG4105C0Z	ABC transporter
Tint_0175	ENOG4108IV0	ABC, transporter
Tint_0177	ENOG4108Z86	Glutamine amidotransferase
Tint_0178	ENOG4105CFQ	glutamine synthetase
Tint_0179	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Tint_0180	ENOG4107RUE	extracellular solute-binding protein family 1
Tint_0181	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Tint_0182	ENOG4105F38	ABC transporter, permease
Tint_0183	ENOG4105D38	putrescine abc transporter
Tint_0186	ENOG4105C26	Dehydrogenase
Tint_0187	ENOG4108JPW	Aminotransferase
Tint_0188	ENOG4107FW0	short-chain dehydrogenase reductase
Tint_0190	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
Tint_0191	ENOG4105C2X	Arabinose 5-phosphate isomerase
Tint_0193	ENOG4105BZU	Histidine kinase
Tint_0195	ENOG4105EXC	Acyl-transferase
Tint_0198	ENOG4105DWV	Homoserine O-trans-acetylase
Tint_0199	ENOG4105DWV	Homoserine O-trans-acetylase
Tint_0200	ENOG4105E0A	ABC, transporter
Tint_0201	ENOG4105EHG	Permease protein
Tint_0207	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
Tint_0208	ENOG4105E0C	molybdate abc transporter
Tint_0209	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
Tint_0218	ENOG4105VEQ	Cold shock protein
Tint_0219	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Tint_0220	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Tint_0227	ENOG4105DSW	Fusaric acid resistance protein
Tint_0229	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Tint_0231	ENOG4105CW7	secretion protein, HlyD family
Tint_0232	ENOG4105ETP	RND efflux system, outer membrane lipoprotein
Tint_0234	ENOG4107RGH	Aldehyde dehydrogenase
Tint_0237	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Tint_0238	ENOG4108UJD	30S ribosomal protein S9
Tint_0239	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Tint_0240	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Tint_0242	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
Tint_0243	ENOG4108T3F	Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes
Tint_0244	ENOG4105DS1	cytochrome b561
Tint_0248	ENOG4105C1G	acyl-Coa dehydrogenase
Tint_0251	ENOG4105BZU	Histidine kinase
Tint_0252	ENOG4105R8A	Heat shock protein
Tint_0253	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
Tint_0256	ENOG4105K64	Glycosyl transferase, family 2
Tint_0257	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Tint_0263	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Tint_0267	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Tint_0269	ENOG4108VP3	Lysine exporter protein (LysE YggA)
Tint_0276	ENOG4105C72	UPF0176 protein
Tint_0278	ENOG4105NQN	cytochrome C
Tint_0281	ENOG4105VZ9	UPF0235 protein
Tint_0283	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Tint_0284	ENOG4107TDF	Formate hydrogenlyase subunit 4
Tint_0286	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Tint_0287	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Tint_0288	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
Tint_0292	ENOG4105D52	delta-aminolevulinic acid dehydratase
Tint_0293	ENOG4108YXA	Membrane
Tint_0297	ENOG4105DZ1	carboxypeptidase
Tint_0298	ENOG4105D7V	transposase
Tint_0300	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Tint_0302	ENOG4105E39	Enoyl-CoA hydratase
Tint_0304	ENOG4105D7V	transposase
Tint_0305	ENOG4108KMM	Diguanylate cyclase
Tint_0307	ENOG4105D7V	transposase
Tint_0309	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Tint_0316	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
Tint_0317	ENOG4105C11	sulfate adenylyltransferase), subunit 2
Tint_0318	ENOG4105CPF	Cell wall formation (By similarity)
Tint_0320	ENOG4107TF3	peptidylprolyl cis-trans isomerase
Tint_0328	ENOG4105C1J	atp-dependent rna helicase
Tint_0330	ENOG4105D7V	transposase
Tint_0331	ENOG4106FRU	abrb family transcriptional regulator
Tint_0332	ENOG4105C5H	ABC transporter
Tint_0334	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
Tint_0335	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
Tint_0336	ENOG4105DFA	alanine racemase domain protein
Tint_0337	ENOG4105CZX	twitching motility protein
Tint_0339	ENOG4105CZX	twitching motility protein
Tint_0341	ENOG4105CEN	a g-specific adenine glycosylase
Tint_0342	ENOG410890F	Dynamin family
Tint_0343	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Tint_0344	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
Tint_0346	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Tint_0347	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Tint_0348	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Tint_0349	ENOG4105NAU	thioesterase Superfamily protein
Tint_0350	ENOG4108JJ7	ABC transporter
Tint_0351	ENOG4107RP9	extracellular solute-binding protein, family 3
Tint_0352	ENOG4105EAD	ABC transporter
Tint_0353	ENOG4105DRP	amino acid AbC transporter
Tint_0354	ENOG4105CDA	abc transporter atp-binding protein
Tint_0355	ENOG4105EKE	dihydroorotase
Tint_0357	ENOG4108V6E	Cell division protein mraZ
Tint_0358	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Tint_0360	ENOG4105CJN	penicillin-binding protein
Tint_0361	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Tint_0362	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Tint_0363	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Tint_0365	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Tint_0366	ENOG4105DFU	Cell wall formation (By similarity)
Tint_0367	ENOG4105CPF	Cell wall formation (By similarity)
Tint_0368	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
Tint_0369	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Tint_0370	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Tint_0371	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Tint_0373	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Tint_0376	ENOG4105M6F	mutator MutT protein
Tint_0377	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
Tint_0378	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
Tint_0379	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Tint_0382	ENOG4107QHF	type ii secretion system protein e
Tint_0383	ENOG4105DFP	Integrase
Tint_0401	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Tint_0402	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Tint_0403	ENOG4108K5P	(LipO)protein
Tint_0404	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tint_0406	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Tint_0407	ENOG4108MN8	Membrane
Tint_0409	ENOG4105CRK	lysyL-tRNA synthetase
Tint_0418	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
Tint_0420	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
Tint_0423	ENOG4105C8N	cysteinyl-tRNA synthetase
Tint_0425	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
Tint_0426	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Tint_0427	ENOG4105CFH	Aspartokinase
Tint_0431	ENOG4105D0S	secretion protein (HlyD
Tint_0432	ENOG4105CJ1	ABC, transporter
Tint_0433	ENOG4105CJ1	ABC, transporter
Tint_0434	ENOG4107QWP	ABC-2 type transporter
Tint_0435	ENOG4107QWP	ABC-2 type transporter
Tint_0439	ENOG4105CY0	Metallo-Beta-Lactamase
Tint_0441	ENOG4108JYK	Dehydrogenase
Tint_0443	ENOG4105C7S	Dehydrogenase
Tint_0448	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Tint_0455	ENOG4105MPD	Cytochrome
Tint_0461	ENOG4105C0H	protease
Tint_0464	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Tint_0465	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Tint_0468	ENOG4105BZU	Histidine kinase
Tint_0469	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
Tint_0470	ENOG41082RQ	UPF0102 protein
Tint_0471	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
Tint_0472	ENOG4105W4M	Transport-associated protein
Tint_0473	ENOG4105F0N	pyrophosphate phospho-hydrolase
Tint_0474	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Tint_0480	ENOG4107RH7	Nicotinate phosphoribosyltransferase
Tint_0484	ENOG4105C5I	Dehydrogenase
Tint_0485	ENOG4107QSV	RmuC domain protein
Tint_0487	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
Tint_0488	ENOG4107QMS	site-determining protein
Tint_0489	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
Tint_0490	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Tint_0492	ENOG4105CHH	sulfate transporter
Tint_0494	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Tint_0496	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
Tint_0510	ENOG4105EAH	synthase
Tint_0511	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Tint_0512	ENOG4105K46	50S ribosomal protein l27
Tint_0513	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Tint_0514	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Tint_0516	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Tint_0517	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Tint_0518	ENOG4105E4C	Lytic transglycosylase catalytic
Tint_0519	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
Tint_0522	ENOG4107TUY	Histidine kinase
Tint_0523	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Tint_0524	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
Tint_0525	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Tint_0526	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Tint_0528	ENOG4105DHP	deoxycytidine triphosphate deaminase
Tint_0529	ENOG4105CH7	arginosuccinase
Tint_0530	ENOG4108HRK	Histidine kinase
Tint_0531	ENOG4108NEV	two component transcriptional regulator, LytTR family
Tint_0532	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Tint_0534	ENOG4106RE7	Cytochrome
Tint_0537	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Tint_0539	ENOG41072GX	Peptidase M22 Glycoprotease
Tint_0540	ENOG4105II7	pyrroline-5-carboxylate reductase
Tint_0543	ENOG4105CAS	nag kinase
Tint_0545	ENOG4108EF9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
Tint_0546	ENOG4105BZU	Histidine kinase
Tint_0547	ENOG4105BZU	Histidine kinase
Tint_0549	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Tint_0550	ENOG4108VWS	Yaeq family
Tint_0551	ENOG4105E27	serine threonine protein kinase
Tint_0552	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Tint_0554	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Tint_0555	ENOG4108XM1	transcriptional regulator AsnC family
Tint_0556	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Tint_0560	ENOG4105EW9	transcriptional regulator AsnC family
Tint_0561	ENOG4107GD3	Catalyzes the conversion of acetoacetate to acetone and carbon dioxide (By similarity)
Tint_0563	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Tint_0564	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Tint_0565	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Tint_0577	ENOG4105CH2	amidohydrolase
Tint_0580	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
Tint_0583	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Tint_0587	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Tint_0588	ENOG4108RA0	tripartite ATP-independent periplasmic transporter, DctQ component
Tint_0589	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Tint_0593	ENOG4105CQ0	ABC transporter
Tint_0594	ENOG4105NSG	hemerythrin hhe cation binding domain protein
Tint_0596	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Tint_0597	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Tint_0599	ENOG4105D64	Mechanosensitive ion channel
Tint_0600	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Tint_0601	ENOG4105BZU	Histidine kinase
Tint_0604	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Tint_0605	ENOG4105EU8	FAD linked oxidase domain protein
Tint_0606	ENOG4105CQB	FAD linked oxidase domain protein
Tint_0608	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
Tint_0612	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Tint_0613	ENOG4105DUM	transcriptional regulator, lysR family
Tint_0614	ENOG4108TWJ	NADH dehydrogenase subunit 5
Tint_0615	ENOG4105EVH	UPF0753 protein
Tint_0616	ENOG4105CVJ	phosphoglycerate mutase
Tint_0617	ENOG41061CK	Antibiotic biosynthesis monooxygenase
Tint_0618	ENOG4105EMU	Dehydrogenase
Tint_0619	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Tint_0620	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Tint_0621	ENOG4105BZS	acriflavin resistance protein
Tint_0624	ENOG4108WBT	adenosyltransferase
Tint_0626	ENOG4105CQB	FAD linked oxidase domain protein
Tint_0637	ENOG4105BZU	Histidine kinase
Tint_0638	ENOG4108VAU	general secretion pathway protein G
Tint_0644	ENOG4105KHS	type IV fimbrial pilin protein
Tint_0645	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Tint_0646	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Tint_0651	ENOG4105D78	K07001 NTE family protein
Tint_0652	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Tint_0654	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
Tint_0655	ENOG4105CRE	cytochrome C
Tint_0656	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
Tint_0657	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
Tint_0658	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Tint_0659	ENOG4105XQ6	frataxin-like protein
Tint_0660	ENOG4108JQC	penicillin-binding protein 1A
Tint_0665	ENOG4105E4G	Type IV pilus
Tint_0667	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
Tint_0668	ENOG4105D49	3-dehydroquinate synthase
Tint_0669	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Tint_0674	ENOG4105CB5	ATP-dependent DNA helicase recG
Tint_0675	ENOG4105C5Q	Transcriptional regulator
Tint_0678	ENOG4105DHQ	Histidine kinase
Tint_0679	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
Tint_0681	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
Tint_0683	ENOG4108UYB	regulatoR
Tint_0684	ENOG41067HS	methyltransferase
Tint_0685	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
Tint_0687	ENOG4105CYM	Glutathione S-transferase
Tint_0689	ENOG4105CGU	Enoyl-CoA hydratase
Tint_0691	ENOG4105C1J	atp-dependent rna helicase
Tint_0697	ENOG4108NH8	Cation transport protein
Tint_0699	ENOG4105DDY	UPF0142 protein ycaO
Tint_0700	ENOG4105T95	Thiol disulfide interChange protein
Tint_0714	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
Tint_0716	ENOG4108KHN	disulfide isomerase, thiol-disulfide oxidase
Tint_0717	ENOG4107ENK	receptor
Tint_0719	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Tint_0721	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
Tint_0722	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
Tint_0723	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Tint_0730	ENOG4105DSB	aldose 1-epimerase
Tint_0731	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
Tint_0732	ENOG4105C26	Dehydrogenase
Tint_0733	ENOG4105EXG	Transcriptional regulator
Tint_0734	ENOG4105D06	uba thif-type nad fad binding protein
Tint_0735	ENOG4105CN1	protease
Tint_0736	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Tint_0737	ENOG4105WZW	rhodanese family
Tint_0738	ENOG4105VW4	glutaredoxin 3
Tint_0739	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
Tint_0740	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Tint_0741	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Tint_0743	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
Tint_0744	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Tint_0745	ENOG4106H78	methyltransferase
Tint_0750	ENOG4105E5M	Multidrug resistance protein D
Tint_0752	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Tint_0759	ENOG4108Z43	UPF0250 protein
Tint_0760	ENOG4107JHD	SlyX family
Tint_0764	ENOG4107R16	Multicopper oxidase
Tint_0767	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tint_0768	ENOG4105F8C	transglutaminase domain-containing protein
Tint_0770	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Tint_0772	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Tint_0773	ENOG4105C32	Amino acid ABC transporter (Permease)
Tint_0775	ENOG4108IV0	ABC, transporter
Tint_0776	ENOG4105C0Z	ABC transporter
Tint_0777	ENOG4105C26	Dehydrogenase
Tint_0779	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Tint_0780	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Tint_0782	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Tint_0783	ENOG4105EZE	Cupin 4 family protein
Tint_0785	ENOG4105GJM	(LipO)protein
Tint_0786	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Tint_0788	ENOG4105CMR	udp-glucose 4-epimerase
Tint_0790	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
Tint_0791	ENOG4105C8V	SAICAR synthetase
Tint_0792	ENOG4107R7Y	intracellular protease Pfpi family
Tint_0793	ENOG4105K63	Thioredoxin
Tint_0794	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Tint_0795	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
Tint_0796	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Tint_0799	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Tint_0800	ENOG4108004	Modulates RecA activity (By similarity)
Tint_0802	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Tint_0803	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Tint_0804	ENOG4108ZCF	integral membrane protein
Tint_0805	ENOG4108ZF3	Phosphatase
Tint_0807	ENOG4105CA9	Pyruvate kinase
Tint_0808	ENOG4105BZU	Histidine kinase
Tint_0811	ENOG4108YSG	O-Antigen polymerase
Tint_0812	ENOG4105ERG	peptidase m48, ste24p
Tint_0813	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Tint_0819	ENOG4105E5Q	amino acid AbC transporter
Tint_0820	ENOG4108HW3	(ABC) transporter
Tint_0821	ENOG4108HW3	(ABC) transporter
Tint_0822	ENOG410804D	Sensor Signal Transduction Histidine Kinase
Tint_0823	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Tint_0825	ENOG41080Z8	PHOSPHOCARRIER protein
Tint_0830	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
Tint_0834	ENOG4105VPX	protein, conserved in bacteria
Tint_0835	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Tint_0836	ENOG41061Y6	folic acid biosynthetic process
Tint_0837	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Tint_0838	ENOG4105W8H	transhydrogenase (subunit alpha
Tint_0840	ENOG4105VFQ	Histone family protein nucleoid-structuring protein H-NS
Tint_0844	ENOG4108IV0	ABC, transporter
Tint_0847	ENOG4105C32	Amino acid ABC transporter (Permease)
Tint_0848	ENOG4105C0Z	ABC transporter
Tint_0851	ENOG4105DHJ	ABC, transporter
Tint_0852	ENOG4105CY3	ABC transporter, permease
Tint_0853	ENOG4107PE3	Mammalian cell entry related domain protein
Tint_0857	ENOG4105DA5	(ABC) transporter
Tint_0858	ENOG4105E3A	(ABC) transporter
Tint_0860	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Tint_0861	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Tint_0862	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
Tint_0863	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Tint_0864	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Tint_0866	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Tint_0867	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Tint_0868	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
Tint_0869	ENOG4105K59	histidine triad (HIT) protein
Tint_0870	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Tint_0871	ENOG4107Z6S	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
Tint_0872	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Tint_0873	ENOG4105C0H	protease
Tint_0874	ENOG4107QNR	UPF0135 protein
Tint_0875	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
Tint_0878	ENOG4105DE4	1-phosphofructokinase
Tint_0879	ENOG4105C12	Phosphoribosylglycinamide synthetase
Tint_0880	ENOG4105CDY	transcriptional regulatory protein
Tint_0881	ENOG4105D7A	ATP-binding protein
Tint_0883	ENOG4105CX6	glutaminyL-tRNA synthetase
Tint_0887	ENOG4105EU0	Major facilitator Superfamily
Tint_0888	ENOG4108UT2	hemolysin iii
Tint_0889	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
Tint_0890	ENOG4105BZU	Histidine kinase
Tint_0892	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Tint_0894	ENOG4108RDT	NADH dehydrogenase NAD(P)H nitroreductase)
Tint_0897	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Tint_0898	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Tint_0899	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Tint_0900	ENOG4108Z1B	Cyclase dehydrase
Tint_0901	ENOG4105VDB	UPF0125 protein
Tint_0902	ENOG4108IV0	ABC, transporter
Tint_0903	ENOG4105C0Z	ABC transporter
Tint_0905	ENOG4105C32	Amino acid ABC transporter (Permease)
Tint_0906	ENOG4105ES9	amino acid
Tint_0908	ENOG4105CRQ	synthase (Component I)
Tint_0909	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
Tint_0911	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
Tint_0913	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
Tint_0914	ENOG4105BZU	Histidine kinase
Tint_0915	ENOG4105BZU	Histidine kinase
Tint_0916	ENOG4108IV0	ABC, transporter
Tint_0917	ENOG4105C0Z	ABC transporter
Tint_0919	ENOG4105C32	Amino acid ABC transporter (Permease)
Tint_0922	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Tint_0923	ENOG4105C2W	permease
Tint_0925	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Tint_0926	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
Tint_0929	ENOG4105CJR	Integral membrane protein (MviN
Tint_0930	ENOG41082GY	Binds directly to 16S ribosomal RNA (By similarity)
Tint_0932	ENOG4105C8Y	Acetylornithine aminotransferase
Tint_0933	ENOG4105DBV	ornithine carbamoyltransferase
Tint_0936	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Tint_0937	ENOG41090A4	Pterin carbinolamine dehydratase
Tint_0938	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
Tint_0939	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
Tint_0940	ENOG4105ECQ	AraC Family Transcriptional Regulator
Tint_0942	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Tint_0944	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
Tint_0946	ENOG4105D16	lipopolysaccharide heptosyltransferase i
Tint_0947	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
Tint_0948	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
Tint_0950	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Tint_0951	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Tint_0953	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Tint_0957	ENOG4107QHF	type ii secretion system protein e
Tint_0960	ENOG4105ECY	inositol monophosphatase
Tint_0961	ENOG4108IYU	L-aspartate oxidase
Tint_0962	ENOG4105MP9	class II Aldolase
Tint_0963	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Tint_0964	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Tint_0978	ENOG41067XB	TonB family
Tint_0985	ENOG4105D16	lipopolysaccharide heptosyltransferase i
Tint_0988	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Tint_0989	ENOG4105EM2	membrane
Tint_0990	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
Tint_0992	ENOG4105ECY	inositol monophosphatase
Tint_0993	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
Tint_0994	ENOG4105D7W	serine acetyltransferase
Tint_0995	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
Tint_0998	ENOG4105F7P	transcriptional regulator AsnC family
Tint_0999	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
Tint_1001	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
Tint_1002	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
Tint_1003	ENOG4105MIR	Phenylalanine 4-monooxygenase
Tint_1004	ENOG4108RXX	maleylacetoacetate isomerase
Tint_1016	ENOG4105EYA	deoxyribonuclease
Tint_1017	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
Tint_1020	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Tint_1021	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Tint_1022	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Tint_1023	ENOG4105K5M	30s ribosomal protein S16
Tint_1027	ENOG4105DJ0	Poly(A) Polymerase
Tint_1029	ENOG4108KZ1	Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA (By similarity)
Tint_1030	ENOG4105C02	permease
Tint_1031	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Tint_1032	ENOG4105FYV	Amp nucleosidase
Tint_1034	ENOG4105CFV	Tetratricopeptide repeat protein
Tint_1035	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
Tint_1036	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
Tint_1037	ENOG4105CBP	Major Facilitator
Tint_1038	ENOG4107SJ1	Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (By similarity)
Tint_1039	ENOG4105C4R	Atp-dependent dna helicase
Tint_1040	ENOG4105CAY	ferredoxin--nadp reductase
Tint_1041	ENOG4108Z4U	Ferredoxin
Tint_1044	ENOG41080HT	Transcriptional regulator, arsr family
Tint_1046	ENOG4105BZM	domain protein
Tint_1047	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Tint_1052	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Tint_1054	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
Tint_1055	ENOG4105DUM	transcriptional regulator, lysR family
Tint_1056	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
Tint_1057	ENOG4105C3J	Cysteine desulfurase
Tint_1058	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
Tint_1059	ENOG4108Z4V	iron-sulfur cluster assembly
Tint_1060	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
Tint_1061	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
Tint_1062	ENOG4108ZIT	Ferredoxin, 2FE-2S
Tint_1063	ENOG4105DKD	Incises the DNA at the 3' side of a lesion during nucleotide excision repair. Incises the DNA farther away from the lesion than UvrC. Not able to incise the 5' site of a lesion. When a lesion remains because UvrC is not able to induce the 3' incision, Cho incises the DNA. Then UvrC makes the 5' incision. The combined action of Cho and UvrC broadens the substrate range of nucleotide excision repair (By similarity)
Tint_1065	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
Tint_1066	ENOG4108EKC	n-acetylglutamate synthase
Tint_1067	ENOG4105CQ7	ATP-dependent helicase
Tint_1070	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
Tint_1076	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
Tint_1078	ENOG4105E09	nadh pyrophosphatase
Tint_1084	ENOG4105D70	Integrase catalytic subunit
Tint_1091	ENOG4107QP8	phosphohexose isomerase
Tint_1092	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
Tint_1093	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Tint_1095	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
Tint_1096	ENOG4108ESZ	Glycogen debranching enzyme
Tint_1097	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Tint_1098	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
Tint_1099	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
Tint_1100	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
Tint_1101	ENOG4108ZMQ	domain protein
Tint_1105	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Tint_1107	ENOG4105E50	uracil-dna glycosylase
Tint_1108	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Tint_1112	ENOG4106RE7	Cytochrome
Tint_1117	ENOG4105CY0	Metallo-Beta-Lactamase
Tint_1120	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Tint_1123	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
Tint_1127	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Tint_1128	ENOG4105E0F	Histidine kinase
Tint_1132	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Tint_1133	ENOG4105K70	DNA-binding protein
Tint_1134	ENOG4107TF3	peptidylprolyl cis-trans isomerase
Tint_1145	ENOG41067CV	Integrase
Tint_1146	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Tint_1148	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
Tint_1149	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
Tint_1152	ENOG4105VTB	flagellar biosynthesis protein fliO
Tint_1153	ENOG4105CN7	Flagellar biosynthetic protein FliP
Tint_1154	ENOG4105VS8	Flagellar biosynthetic protein fliq
Tint_1155	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
Tint_1156	ENOG4105D00	flagellar biosynthetic protein flhB
Tint_1157	ENOG4105D7B	Flagellar biosynthesis protein flha
Tint_1158	ENOG4105FZW	flagellar biosynthesis regulator FlhF
Tint_1159	ENOG4107R21	site-determining protein
Tint_1160	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tint_1161	ENOG4105E14	MotA TolQ exbB proton channel
Tint_1165	ENOG4105D00	flagellar biosynthetic protein flhB
Tint_1166	ENOG4105BZU	Histidine kinase
Tint_1168	ENOG4105UKP	Protein of unknown function (DUF1778)
Tint_1169	ENOG4105BZU	Histidine kinase
Tint_1170	ENOG4105C8Q	Methyl-accepting chemotaxis
Tint_1171	ENOG4107R88	Chemotaxis protein (CheV)
Tint_1172	ENOG4107SDU	Methyl-accepting chemotaxis
Tint_1176	ENOG4105CBS	Chea signal transduction histidine kinase
Tint_1178	ENOG4108VYJ	response regulator receiver protein
Tint_1182	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
Tint_1183	ENOG41085EG	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
Tint_1185	ENOG4105D58	Diguanylate phosphodiesterase
Tint_1188	ENOG4105E1Q	flagellar hook-associated protein
Tint_1190	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
Tint_1191	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
Tint_1192	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
Tint_1193	ENOG4105CGA	flagellar basal-body rod protein FlgG
Tint_1194	ENOG4108KPB	Flagellar basal-body rod protein FlgF
Tint_1195	ENOG4105BZE	flagellar hook protein, FlgE
Tint_1197	ENOG4108ZC9	flagellar basal-body rod protein flgc
Tint_1198	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
Tint_1208	ENOG4105MQ3	flagellar protein FliS
Tint_1210	ENOG4106VK6	Flagellar motor protein
Tint_1213	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Tint_1214	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
Tint_1215	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
Tint_1216	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Tint_1218	ENOG4108JIR	Flagellum-specific ATP synthase
Tint_1222	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
Tint_1223	ENOG4105DD5	Flagellar motor switch protein
Tint_1224	ENOG4105C8Q	Methyl-accepting chemotaxis
Tint_1225	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Tint_1226	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
Tint_1227	ENOG4105BZU	Histidine kinase
Tint_1228	ENOG4105BZU	Histidine kinase
Tint_1229	ENOG4105C8Q	Methyl-accepting chemotaxis
Tint_1230	ENOG4108V3W	Chemotaxis protein, CheW
Tint_1231	ENOG4105C8Q	Methyl-accepting chemotaxis
Tint_1232	ENOG4105C8Q	Methyl-accepting chemotaxis
Tint_1233	ENOG4105CBS	Chea signal transduction histidine kinase
Tint_1235	ENOG4108VYJ	response regulator receiver protein
Tint_1236	ENOG4107WTJ	Methyl-accepting chemotaxis sensory transducer
Tint_1238	ENOG4108WQH	regulatoR
Tint_1240	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Tint_1241	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Tint_1242	ENOG4105DQR	SNARE associated Golgi
Tint_1243	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Tint_1244	ENOG4105HDK	L-asparaginase
Tint_1246	ENOG4105CUV	Homoserine Kinase
Tint_1248	ENOG4105C2M	dna polymerase I
Tint_1253	ENOG4105CPC	Aldo Keto reductase
Tint_1255	ENOG4105CS1	NAD(P)H quinone oxidoreductase
Tint_1258	ENOG4105CR8	Transcriptional regulator
Tint_1259	ENOG4105EUB	pirin domain protein
Tint_1263	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Tint_1272	ENOG4105E3B	Multicopper oxidase
Tint_1283	ENOG4105CEY	Amp-dependent synthetase and ligase
Tint_1285	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
Tint_1286	ENOG4105E43	Extracellular solute-binding protein, family 5
Tint_1287	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
Tint_1288	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
Tint_1289	ENOG4108JQ5	ABC transporter
Tint_1290	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Tint_1291	ENOG4105CHV	Transcription elongation factor NusA
Tint_1292	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Tint_1293	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Tint_1294	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Tint_1301	ENOG4108IAJ	Nad-dependent epimerase dehydratase
Tint_1302	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Tint_1304	ENOG4105DB1	molybdopterin oxidoreductase
Tint_1305	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Tint_1306	ENOG4108KDI	dmso reductase anchor subunit
Tint_1310	ENOG4105DVT	helicase
Tint_1312	ENOG4105C34	Pseudouridine synthase
Tint_1313	ENOG4105K64	Glycosyl transferase, family 2
Tint_1314	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
Tint_1315	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
Tint_1316	ENOG4105CHU	acetyl-coa acetyltransferase
Tint_1317	ENOG4105CHR	reductase
Tint_1319	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Tint_1321	ENOG4108VCT	Sulfite exporter TauE/SafE
Tint_1322	ENOG4106HK8	GPR1 FUN34 yaaH family protein
Tint_1326	ENOG4105CGK	Exodeoxyribonuclease III
Tint_1327	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Tint_1328	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Tint_1329	ENOG4105DTN	riboflavin biosynthesis protein ribF
Tint_1330	ENOG4105VEQ	Cold shock protein
Tint_1331	ENOG4105KHU	inner membrane protein YohD
Tint_1332	ENOG4105C31	Tryptophanyl-tRNA synthetase
Tint_1333	ENOG4108Z4T	Peptidase M50
Tint_1334	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
Tint_1335	ENOG4105DB7	PHP domain protein
Tint_1336	ENOG4108Z66	YbaK ebsC protein
Tint_1337	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Tint_1339	ENOG4108VPT	UPF0234 protein
Tint_1340	ENOG4105D4A	Cell wall formation (By similarity)
Tint_1342	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Tint_1344	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
Tint_1345	ENOG4105C7S	Dehydrogenase
Tint_1346	ENOG4107QN2	dihydrolipoyl dehydrogenase
Tint_1347	ENOG4105D6Z	AFG1 family ATPase
Tint_1349	ENOG4105D8X	mechanosensitive ion channel
Tint_1350	ENOG4105CEY	Amp-dependent synthetase and ligase
Tint_1351	ENOG4105BZJ	Electron transfer flavoprotein
Tint_1352	ENOG4105C10	Electron transfer flavoprotein
Tint_1353	ENOG4105CSU	acyl-Coa dehydrogenase
Tint_1356	ENOG4107S2Z	UPF0761 membrane protein
Tint_1357	ENOG4105CS1	NAD(P)H quinone oxidoreductase
Tint_1359	ENOG4105CQB	FAD linked oxidase domain protein
Tint_1360	ENOG4105EYW	Ion transport protein
Tint_1361	ENOG4105DFP	Integrase
Tint_1362	ENOG4107RZZ	dna polymerase iii epsilon subunit
Tint_1363	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
Tint_1365	ENOG4105E0F	Histidine kinase
Tint_1366	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Tint_1369	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Tint_1370	ENOG4105C22	threonyL-tRNA synthetase
Tint_1371	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Tint_1373	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Tint_1374	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Tint_1375	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Tint_1376	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Tint_1377	ENOG4105WJX	transcriptional regulator MERR family
Tint_1378	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Tint_1379	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Tint_1384	ENOG4105CSH	Transporter
Tint_1387	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
Tint_1388	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Tint_1389	ENOG4105BZ1	(ABC) transporter
Tint_1391	ENOG4105DR5	peptidase
Tint_1392	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Tint_1394	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
Tint_1395	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Tint_1412	ENOG4105CJ2	(LipO)protein
Tint_1414	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Tint_1417	ENOG4105CEY	Amp-dependent synthetase and ligase
Tint_1419	ENOG4105C5F	glutamine synthetase
Tint_1421	ENOG4105CUX	Signal transduction histidine kinase
Tint_1422	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Tint_1425	ENOG4105E0A	ABC, transporter
Tint_1427	ENOG4105C01	Dihydroxy-acid dehydratase
Tint_1428	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Tint_1433	ENOG4108ESU	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane (By similarity)
Tint_1434	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
Tint_1435	ENOG4107SVH	Potassium channel protein
Tint_1436	ENOG4107TF3	peptidylprolyl cis-trans isomerase
Tint_1437	ENOG4105M85	Bola protein
Tint_1438	ENOG4107835	probably involved in intracellular septation (By similarity)
Tint_1439	ENOG4105CY0	Metallo-Beta-Lactamase
Tint_1445	ENOG4105DJ9	glucan biosynthesis protein
Tint_1446	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
Tint_1447	ENOG4105DJ9	glucan biosynthesis protein
Tint_1451	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
Tint_1452	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
Tint_1453	ENOG4108ETH	Formylglycinamide ribotide synthetase
Tint_1457	ENOG4105KPV	Transcriptional regulator
Tint_1460	ENOG4105NAA	Cytochrome C oxidase, subunit II
Tint_1461	ENOG4107RQ2	Cytochrome c oxidase, subunit I
Tint_1462	ENOG4108ZX6	Electron transport protein SCO1 SenC
Tint_1470	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
Tint_1471	ENOG4105EW9	transcriptional regulator AsnC family
Tint_1472	ENOG4105DEN	Luciferase family
Tint_1473	ENOG4105VEJ	Heat shock protein
Tint_1474	ENOG410846T	CoA-transferase family III
Tint_1477	ENOG4105HHA	aminodeoxychorismate lyase
Tint_1478	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Tint_1479	ENOG4107QRG	dna polymerase iii
Tint_1481	ENOG4105F8V	Hydrolase, tatD family
Tint_1483	ENOG4105CXN	decarboxylase
Tint_1485	ENOG4107QX8	SPFH domain, Band 7 family protein
Tint_1486	ENOG4105ED9	Protein of unknown function (DUF455)
Tint_1490	ENOG4105EYW	Ion transport protein
Tint_1491	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
Tint_1492	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Tint_1494	ENOG4105CNG	UPF0061 protein
Tint_1495	ENOG4105E0X	reductase
Tint_1496	ENOG4105DKQ	ROK family
Tint_1498	ENOG4105CMM	transposase
Tint_1500	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Tint_1502	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Tint_1503	ENOG4105CSM	endonuclease III
Tint_1504	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
Tint_1511	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Tint_1513	ENOG4105CPK	Glycosyl transferase (Group 1
Tint_1514	ENOG4107S90	membrAne
Tint_1515	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Tint_1516	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Tint_1520	ENOG4105E5H	Transposase
Tint_1531	ENOG4107QMH	DNA methylase
Tint_1534	ENOG4105CAF	HipA N-terminal domain protein
Tint_1538	ENOG4105DFP	Integrase
Tint_1545	ENOG4105D85	methylase
Tint_1548	ENOG4105F6A	helicase
Tint_1549	ENOG4105ECI	YeeC-like protein
Tint_1556	ENOG4105DFP	Integrase
Tint_1559	ENOG4105F5W	AtP-binding protein
Tint_1565	ENOG4108IV0	ABC, transporter
Tint_1566	ENOG4105C0Z	ABC transporter
Tint_1567	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Tint_1568	ENOG4105C32	Amino acid ABC transporter (Permease)
Tint_1570	ENOG4105EUZ	Beta-lactamase domain protein
Tint_1572	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
Tint_1577	ENOG4105F5W	AtP-binding protein
Tint_1578	ENOG4105D70	Integrase catalytic subunit
Tint_1583	ENOG4105CHF	Glutathione S-transferase
Tint_1584	ENOG4105CKI	cobalamin synthesis protein
Tint_1585	ENOG4105CI2	imidazolone-5-propionate hydrolase
Tint_1587	ENOG4105CEY	Amp-dependent synthetase and ligase
Tint_1591	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
Tint_1592	ENOG4105CHR	reductase
Tint_1593	ENOG4105CSU	acyl-Coa dehydrogenase
Tint_1594	ENOG4105CHU	acetyl-coa acetyltransferase
Tint_1596	ENOG4108N5B	2-phosphosulfolactate phosphatase
Tint_1597	ENOG4105D74	hydrolase
Tint_1600	ENOG4105CC9	acyl-Coa dehydrogenase
Tint_1603	ENOG4105DTD	Dehydrogenase
Tint_1610	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Tint_1611	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
Tint_1612	ENOG4105FAV	ABC, transporter
Tint_1613	ENOG4105FDK	ABC transporter
Tint_1615	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Tint_1616	ENOG410635M	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
Tint_1617	ENOG4105CTB	Polyprenyl synthetase
Tint_1618	ENOG41082UU	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Tint_1620	ENOG4105KHC	sulfurtransferase
Tint_1623	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
Tint_1625	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
Tint_1626	ENOG4105C2I	pirin domain protein
Tint_1629	ENOG4105UIB	(ABC) transporter
Tint_1630	ENOG4105C2J	ABC transporter
Tint_1631	ENOG4107QUY	Guanine deaminase
Tint_1632	ENOG4105C7N	Xanthine uracil vitamin C permease
Tint_1635	ENOG4105C7W	Xanthine dehydrogenase
Tint_1637	ENOG4105C01	Dihydroxy-acid dehydratase
Tint_1638	ENOG4106NZI	LysR family Transcriptional regulator
Tint_1639	ENOG4105CMM	transposase
Tint_1646	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Tint_1647	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Tint_1649	ENOG4105W5Q	DNA repair protein (RadC
Tint_1652	ENOG4105CV6	ABC transporter, permease
Tint_1656	ENOG4105DUM	transcriptional regulator, lysR family
Tint_1657	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Tint_1658	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Tint_1659	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Tint_1660	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Tint_1662	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Tint_1664	ENOG4105CHR	reductase
Tint_1666	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Tint_1667	ENOG4105CAQ	asparagine synthetase
Tint_1670	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Tint_1672	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tint_1675	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Tint_1676	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
Tint_1677	ENOG4105W49	UPF0434 protein
Tint_1678	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
Tint_1679	ENOG4105M8F	Biopolymer transport protein exbD tolR
Tint_1681	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Tint_1682	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Tint_1689	ENOG4108ECM	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
Tint_1690	ENOG4108JA2	transcriptioN-repair coupling factor
Tint_1691	ENOG4105EAC	phosphoserine phosphatase
Tint_1693	ENOG4105C28	cystathionine
Tint_1698	ENOG4105C9Q	fumarate hydratase class II
Tint_1699	ENOG4107TDF	Formate hydrogenlyase subunit 4
Tint_1701	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Tint_1702	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Tint_1703	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
Tint_1704	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Tint_1705	ENOG4105WMR	Protein CrcB homolog
Tint_1706	ENOG4105KJJ	Uncharacterized ACR, COG1993
Tint_1708	ENOG4105C98	muts2 protein
Tint_1709	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Tint_1710	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Tint_1711	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
Tint_1713	ENOG4105GCF	PGAM
Tint_1714	ENOG4105C9X	ppx gppa phosphatase
Tint_1715	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
Tint_1716	ENOG4105BZU	Histidine kinase
Tint_1717	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Tint_1719	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Tint_1721	ENOG4105C8U	phosphate abc transporter
Tint_1723	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Tint_1725	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Tint_1727	ENOG4105HBR	Rna-binding protein
Tint_1729	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Tint_1730	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Tint_1731	ENOG4108NIW	Leucine export protein LeuE
Tint_1734	ENOG4105CSU	acyl-Coa dehydrogenase
Tint_1735	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
Tint_1737	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Tint_1738	ENOG4105CKK	Glycosyl transferase, family 2
Tint_1740	ENOG4108JU4	Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
Tint_1741	ENOG4105K63	Thioredoxin
Tint_1742	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Tint_1743	ENOG4105NRA	50s ribosomal protein l31 type b
Tint_1745	ENOG4107QI1	Mate efflux family protein
Tint_1747	ENOG4105C5H	ABC transporter
Tint_1748	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
Tint_1749	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Tint_1750	ENOG4105CZX	twitching motility protein
Tint_1751	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
Tint_1752	ENOG4105CHM	Aminotransferase
Tint_1756	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
Tint_1757	ENOG4108Z6B	deaminase
Tint_1759	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Tint_1760	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Tint_1763	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Tint_1764	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
Tint_1766	ENOG4105EPW	hflc protein
Tint_1767	ENOG4107QJR	hflk protein
Tint_1768	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Tint_1769	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
Tint_1771	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
Tint_1772	ENOG4105N21	Membrane
Tint_1773	ENOG4105CUT	histidyl-tRNA synthetase
Tint_1774	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Tint_1777	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Tint_1778	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Tint_1779	ENOG4105FE9	pseudouridine synthase
Tint_1780	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Tint_1782	ENOG4108YZA	Nitrogen regulatory protein pii
Tint_1783	ENOG4105C4K	Nad synthetase
Tint_1787	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Tint_1788	ENOG4105CFG	Acts as a chaperone (By similarity)
Tint_1789	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Tint_1791	ENOG4105CD8	aminopeptidase N
Tint_1792	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
Tint_1797	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
Tint_1798	ENOG4105K8N	protein family UPF0079, ATPase
Tint_1799	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Tint_1800	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
Tint_1801	ENOG4105F73	Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
Tint_1804	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
Tint_1810	ENOG4107QWP	ABC-2 type transporter
Tint_1811	ENOG4107QWP	ABC-2 type transporter
Tint_1812	ENOG4105CJ1	ABC, transporter
Tint_1815	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
Tint_1819	ENOG4105C54	Major Facilitator superfamily
Tint_1820	ENOG4105CSR	polyphosphate kinase 2
Tint_1826	ENOG4108UXE	Protein tyrosine phosphatase
Tint_1830	ENOG4105BZU	Histidine kinase
Tint_1833	ENOG4105C6T	cysteine synthase
Tint_1836	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Tint_1837	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
Tint_1838	ENOG4105D78	K07001 NTE family protein
Tint_1840	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
Tint_1843	ENOG4105BZS	acriflavin resistance protein
Tint_1844	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
Tint_1847	ENOG4105D8V	Glucose sorbosone dehydrogenase
Tint_1848	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Tint_1849	ENOG4105CGF	Aromatic amino acid aminotransferase
Tint_1851	ENOG4108R3D	Electron transport complex
Tint_1852	ENOG4107YRI	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
Tint_1855	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Tint_1856	ENOG4107QMP	dna polymerase iii subunits gamma and tau
Tint_1862	ENOG4105EX9	Membrane
Tint_1864	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Tint_1865	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Tint_1866	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Tint_1867	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Tint_1869	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Tint_1871	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
Tint_1872	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Tint_1874	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Tint_1876	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Tint_1880	ENOG4105CMM	transposase
Tint_1887	ENOG4108RAV	Conserved protein
Tint_1889	ENOG4107F83	nucleotidyltransferase DNA polymerase involved in DNA
Tint_1890	ENOG4105C0B	DNA polymerase III (alpha subunit)
Tint_1908	ENOG4105J1P	transposase, IS3 IS911 family protein
Tint_1916	ENOG4105CMM	transposase
Tint_1928	ENOG4105DFP	Integrase
Tint_1931	ENOG4105J1P	transposase, IS3 IS911 family protein
Tint_1943	ENOG4105HEI	LysR family (Transcriptional regulator
Tint_1946	ENOG4105F2I	Transposase
Tint_1956	ENOG4105EQ0	Major Facilitator superfamily
Tint_1984	ENOG4105E5H	Transposase
Tint_1991	ENOG4108Z4X	TRANSCRIPTIONal
Tint_1993	ENOG4108IND	Tetr family transcriptional regulator
Tint_2000	ENOG4105HEI	LysR family (Transcriptional regulator
Tint_2003	ENOG4108W5M	transcriptional regulator
Tint_2016	ENOG4107QMH	DNA methylase
Tint_2018	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Tint_2020	ENOG4105EHE	chorismate mutase- prephenate dehydrogenase
Tint_2025	ENOG4106CY5	excisionase
Tint_2026	ENOG4105W7J	DNA binding
Tint_2027	ENOG410649Z	repressor
Tint_2028	ENOG4108UUM	single-stranded DNA-binding protein
Tint_2033	ENOG4105CPC	Aldo Keto reductase
Tint_2034	ENOG410642W	LysR family Transcriptional regulator
Tint_2036	ENOG4105DUM	transcriptional regulator, lysR family
Tint_2042	ENOG4108MP6	LysR family Transcriptional regulator
Tint_2044	ENOG4105KVH	Transcriptional regulator
Tint_2045	ENOG4105C57	major facilitator superfamily
Tint_2047	ENOG4105CBP	Major Facilitator
Tint_2049	ENOG4105EGI	Transcriptional regulator
Tint_2050	ENOG4105ETT	transcriptional Regulator, LysR family
Tint_2053	ENOG4107NQ8	LysR family Transcriptional regulator
Tint_2056	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Tint_2059	ENOG4108YYH	Nadph-dependent fmn reductase
Tint_2065	ENOG4108NIW	Leucine export protein LeuE
Tint_2069	ENOG4105DFP	Integrase
Tint_2070	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Tint_2071	ENOG4108TEB	UPF0114 protein
Tint_2074	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Tint_2075	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Tint_2079	ENOG4107S7U	Sulfide dehydrogenase
Tint_2083	ENOG4105HF0	Membrane
Tint_2084	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
Tint_2094	ENOG4108QV3	biosynthesis protein
Tint_2095	ENOG4105C0W	non-ribosomal peptide synthetase
Tint_2098	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Tint_2099	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Tint_2100	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Tint_2101	ENOG4105E9H	Lytic Murein transglycosylase
Tint_2102	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Tint_2107	ENOG4108ZAF	Molybdopterin
Tint_2109	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Tint_2110	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
Tint_2112	ENOG4105D6E	homoserine dehydrogenase
Tint_2113	ENOG4105CHM	Aminotransferase
Tint_2115	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Tint_2116	ENOG4108IAB	Phoh family
Tint_2117	ENOG4105CDU	Replicative dna helicase
Tint_2118	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Tint_2119	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Tint_2121	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
Tint_2123	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
Tint_2126	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Tint_2127	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Tint_2128	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Tint_2129	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Tint_2130	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Tint_2132	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Tint_2133	ENOG4105DZP	Membrane-associated zinc metalloprotease
Tint_2134	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Tint_2135	ENOG4105KNE	Phosphatidate cytidylyltransferase
Tint_2139	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Tint_2140	ENOG4105CE9	30S ribosomal protein S2
Tint_2142	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Tint_2143	ENOG4108I0Y	(ABC) transporter
Tint_2144	ENOG4108UJV	acyl-CoA thioesterase i
Tint_2145	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
Tint_2146	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Tint_2148	ENOG4107T8Q	Glycosyl transferase (Group 1
Tint_2149	ENOG4105D7W	serine acetyltransferase
Tint_2150	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
Tint_2151	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
Tint_2152	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
Tint_2153	ENOG4108ZP8	Acetolactate synthase small subunit
Tint_2154	ENOG4105C7K	acetolactate synthase
Tint_2161	ENOG4105EXG	Transcriptional regulator
Tint_2162	ENOG4105CH5	extracellular solute-binding protein, family 7
Tint_2163	ENOG4105CH5	extracellular solute-binding protein, family 7
Tint_2164	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
Tint_2165	ENOG4105N42	UPF0307 protein
Tint_2166	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
Tint_2167	ENOG41066FR	extracellular solute-binding protein
Tint_2169	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Tint_2170	ENOG4105BZU	Histidine kinase
Tint_2171	ENOG4105CPC	Aldo Keto reductase
Tint_2172	ENOG4105BZU	Histidine kinase
Tint_2173	ENOG4105ETE	Transcriptional regulator (LacI family
Tint_2174	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Tint_2175	ENOG4105DE4	1-phosphofructokinase
Tint_2176	ENOG4105DM4	PTS System
Tint_2178	ENOG4107QTZ	amino acid
Tint_2181	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Tint_2182	ENOG4105DU1	integral membrane protein, terc
Tint_2184	ENOG4108MN8	Membrane
Tint_2185	ENOG41063Z6	transcriptional regulator, lysR family
Tint_2187	ENOG4105D5P	Methylmalonyl-coA mutase
Tint_2189	ENOG4105FE9	pseudouridine synthase
Tint_2191	ENOG4105CA9	Pyruvate kinase
Tint_2192	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Tint_2193	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
Tint_2194	ENOG4105EIX	cytochrome c1
Tint_2195	ENOG4107MKT	Stringent starvation protein a
Tint_2196	ENOG4105KB2	stringent starvation protein b
Tint_2211	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Tint_2214	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
Tint_2215	ENOG4105CV8	reductase
Tint_2217	ENOG4105EQ0	Major Facilitator superfamily
Tint_2218	ENOG4105SYT	Methylenetetrahydrofolate reductase
Tint_2219	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Tint_2220	ENOG410829K	Lysine exporter protein (Lyse ygga)
Tint_2223	ENOG4105CDH	Citrulline--aspartate ligase
Tint_2224	ENOG4105NBK	UPF0345 protein
Tint_2226	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Tint_2229	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Tint_2231	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Tint_2233	ENOG4105CKI	cobalamin synthesis protein
Tint_2234	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Tint_2236	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Tint_2237	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Tint_2238	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Tint_2240	ENOG4105VT2	5-hydroxyisourate hydrolase
Tint_2241	ENOG4107YCY	Transcriptional regulator
Tint_2244	ENOG4107S4Y	M20 DapE family protein YgeY
Tint_2249	ENOG4105FCD	Major Facilitator
Tint_2252	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Tint_2253	ENOG4108YZ4	nudix hydrolase
Tint_2255	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Tint_2256	ENOG4105C8S	subunit m
Tint_2259	ENOG4105DF2	NADH dehydrogenase subunit j
Tint_2261	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Tint_2262	ENOG4108IEH	NADH dehydrogenase subunit g
Tint_2265	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Tint_2266	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Tint_2267	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Tint_2268	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Tint_2270	ENOG4105CP7	Triose-phosphate isomerase
Tint_2271	ENOG4105CPQ	Dehydrogenase
Tint_2272	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Tint_2274	ENOG4105VN1	Heat shock protein
Tint_2276	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Tint_2277	ENOG4105CBX	hi0933 family
Tint_2278	ENOG4105VCC	30S ribosomal protein S21
Tint_2280	ENOG4108MUZ	hydrolase
Tint_2281	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Tint_2282	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
Tint_2284	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Tint_2285	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
Tint_2286	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
Tint_2287	ENOG4108Z0R	Transferase
Tint_2288	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
Tint_2289	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
Tint_2290	ENOG4107QR9	Iron-sulfur cluster binding protein
Tint_2293	ENOG41061WM	D-Alanyl-D-Alanine
Tint_2294	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
Tint_2299	ENOG4105W2Z	cytochrome C, class I
Tint_2300	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
Tint_2302	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Tint_2303	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
Tint_2304	ENOG4105K4H	Nlp p60 protein
Tint_2305	ENOG4107QN2	dihydrolipoyl dehydrogenase
Tint_2306	ENOG4107QSN	dihydrolipoamide acetyltransferase
Tint_2307	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
Tint_2308	ENOG4105BZU	Histidine kinase
Tint_2309	ENOG4108ZXC	Two component transcriptional regulator, luxr family
Tint_2310	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Tint_2311	ENOG4105DGW	oligopeptidase A
Tint_2313	ENOG4105E66	phosphoriboisomerase A
Tint_2314	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
Tint_2316	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Tint_2317	ENOG4105C28	cystathionine
Tint_2318	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
Tint_2319	ENOG4105E96	Colicin v production protein
Tint_2321	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Tint_2322	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
Tint_2323	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Tint_2324	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Tint_2325	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Tint_2328	ENOG4107QJH	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Tint_2329	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Tint_2330	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Tint_2332	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Tint_2333	ENOG4105F2W	methyltransferase
Tint_2335	ENOG4105BZN	citrate synthase
Tint_2336	ENOG41060IS	Flavinator of succinate dehydrogenase
Tint_2337	ENOG4105E33	succinate dehydrogenase
Tint_2338	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
Tint_2339	ENOG4105N1I	succinate dehydrogenase, hydrophobic membrane anchor protein
Tint_2341	ENOG4105FDP	GntR family transcriptional regulator
Tint_2342	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Tint_2343	ENOG4105CR4	methylisocitrate lyase
Tint_2344	ENOG4105BZN	citrate synthase
Tint_2346	ENOG4105DXD	2-methylcitrate dehydratase
Tint_2347	ENOG4107QM5	aconitate hydratase
Tint_2348	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
Tint_2349	ENOG4105KUZ	arsenate reductase
Tint_2350	ENOG4105D1Q	UPF0246 protein
Tint_2351	ENOG4108JU3	Alkyl hydroperoxide reductase
Tint_2352	ENOG4105D3R	alkyl hydroperoxide reductase
Tint_2353	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Tint_2355	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
Tint_2356	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Tint_2357	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
Tint_2359	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
Tint_2360	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Tint_2366	ENOG4105C5H	ABC transporter
Tint_2369	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
Tint_2370	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
Tint_2371	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Tint_2372	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Tint_2374	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
Tint_2375	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
Tint_2377	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
Tint_2378	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Tint_2379	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Tint_2381	ENOG4105C3F	Signal peptidase i
Tint_2382	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Tint_2383	ENOG4105C0H	protease
Tint_2386	ENOG4105EMN	RNA polymerase sigma factor
Tint_2388	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Tint_2389	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Tint_2390	ENOG4105CHR	reductase
Tint_2391	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Tint_2392	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Tint_2393	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Tint_2394	ENOG4105VGS	50s ribosomal protein l32
Tint_2395	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
Tint_2397	ENOG4105KFG	YeeE YedE family protein
Tint_2398	ENOG4108UHJ	MAF-like protein
Tint_2399	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Tint_2404	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Tint_2405	ENOG4105EI2	Pseudouridine synthase
Tint_2406	ENOG4105C03	ribonuclease
Tint_2407	ENOG4108535	NAD dependent epimerase/dehydratase family
Tint_2408	ENOG4108EX3	reductase
Tint_2409	ENOG4108IV0	ABC, transporter
Tint_2410	ENOG4105C0Z	ABC transporter
Tint_2411	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Tint_2412	ENOG4105C32	Amino acid ABC transporter (Permease)
Tint_2413	ENOG4105D1H	recombination factor protein RarA
Tint_2414	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
Tint_2415	ENOG4105CNU	cell division protein FtsK
Tint_2416	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
Tint_2417	ENOG4105C3M	thioredoxin reductase
Tint_2418	ENOG4105KDC	50s ribosomal protein l28
Tint_2419	ENOG4105W0E	50S ribosomal protein L33
Tint_2422	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Tint_2423	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Tint_2424	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Tint_2428	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Tint_2429	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Tint_2430	ENOG4107YIM	Involved in the transcription termination process (By similarity)
Tint_2434	ENOG4107YD3	Thioesterase
Tint_2435	ENOG4105E02	MotA TolQ exbB proton channel
Tint_2436	ENOG4105M8F	Biopolymer transport protein exbD tolR
Tint_2438	ENOG4105C0B	DNA polymerase III (alpha subunit)
Tint_2442	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
Tint_2443	ENOG4105CND	Glycosyl transferase, family 2
Tint_2445	ENOG4105BZ1	(ABC) transporter
Tint_2447	ENOG4106WTF	Glycosyl transferase, family 2
Tint_2449	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
Tint_2450	ENOG4105KCK	Peptidoglycan-associated lipoprotein
Tint_2452	ENOG4105CUC	YeeE YedE family protein
Tint_2453	ENOG4105CUZ	uba thif-type nad fad binding protein
Tint_2462	ENOG4105KPV	Transcriptional regulator
Tint_2463	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
Tint_2465	ENOG4105VG1	fes assembly suf system protein
Tint_2466	ENOG4108UNV	SUF system FeS assembly protein, NifU family
Tint_2467	ENOG4105C9B	Cysteine desulfurase
Tint_2469	ENOG4105C3K	feS assembly ATPase SufC
Tint_2473	ENOG4105BZU	Histidine kinase
Tint_2474	ENOG4105WH1	Two component transcriptional regulator luxr family
Tint_2477	ENOG4105CRU	nitrate reductase, alpha subunit
Tint_2478	ENOG4108IUE	nitrate reductase beta subunit
Tint_2479	ENOG4108NZN	Respiratory nitrate reductase 2 delta chain
Tint_2480	ENOG41076YT	nitrate reductase, gamma subunit
Tint_2496	ENOG4105TNS	Conserved Protein
Tint_2498	ENOG4107Z67	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
Tint_2502	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
Tint_2505	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
Tint_2512	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Tint_2514	ENOG4105C7Z	Conserved Protein
Tint_2515	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Tint_2517	ENOG4105BZU	Histidine kinase
Tint_2518	ENOG4105CEY	Amp-dependent synthetase and ligase
Tint_2519	ENOG4105C4R	Atp-dependent dna helicase
Tint_2522	ENOG4107SC1	transglycosylase
Tint_2523	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
Tint_2524	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
Tint_2526	ENOG4108MGI	Transcriptional regulator
Tint_2528	ENOG4108MXF	Alpha Beta Hydrolase
Tint_2530	ENOG4105IPS	esterase
Tint_2531	ENOG4105CHR	reductase
Tint_2534	ENOG4105E2X	shikimate dehydrogenase
Tint_2535	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
Tint_2536	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Tint_2537	ENOG4105DWF	phosphomethylpyrimidine kinase
Tint_2538	ENOG4105VCQ	rubredoxin
Tint_2539	ENOG4108UNF	response regulator
Tint_2540	ENOG4105M3Z	response regulator
Tint_2542	ENOG4105C8Q	Methyl-accepting chemotaxis
Tint_2543	ENOG4105CBS	Chea signal transduction histidine kinase
Tint_2544	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
Tint_2545	ENOG4108UJU	UPF0301 protein
Tint_2546	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Tint_2547	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Tint_2548	ENOG4105CXT	aspartate transcarbamylase
Tint_2549	ENOG4105CD3	dihydroorotase
Tint_2550	ENOG4108Z20	Acyl-transferase
Tint_2555	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Tint_2556	ENOG4105DFU	Cell wall formation (By similarity)
Tint_2557	ENOG4108Z03	MAF-like protein
Tint_2558	ENOG4105C03	ribonuclease
Tint_2562	ENOG4105CVE	Lytic murein transglycosylase
Tint_2563	ENOG4105BZU	Histidine kinase
Tint_2565	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
Tint_2567	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
Tint_2568	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Tint_2569	ENOG4105EJQ	L-serine dehydratase
Tint_2570	ENOG4105C5W	Aldolase
Tint_2571	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Tint_2572	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
Tint_2573	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Tint_2575	ENOG4105W2Z	cytochrome C, class I
Tint_2579	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
Tint_2580	ENOG4108M8S	permease YjgP YjgQ family protein
Tint_2582	ENOG4107R11	Transcriptional regulator
Tint_2583	ENOG4105CHM	Aminotransferase
Tint_2584	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
Tint_2591	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
Tint_2594	ENOG4105CV4	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
Tint_2596	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Tint_2597	ENOG41081UC	Inherit from COG: Competence protein
Tint_2598	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
Tint_2600	ENOG4105CHU	acetyl-coa acetyltransferase
Tint_2602	ENOG4105CSU	acyl-Coa dehydrogenase
Tint_2604	ENOG4108J2R	molybdopterin oxidoreductase
Tint_2606	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
Tint_2608	ENOG4105CJ1	ABC, transporter
Tint_2610	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Tint_2611	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Tint_2612	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Tint_2613	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Tint_2614	ENOG41067V7	50S ribosomal protein L36
Tint_2616	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Tint_2617	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Tint_2618	ENOG4105VPB	50S ribosomal protein L30
Tint_2619	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Tint_2620	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Tint_2621	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Tint_2622	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Tint_2623	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Tint_2624	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Tint_2625	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Tint_2626	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Tint_2628	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Tint_2629	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Tint_2630	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Tint_2632	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Tint_2633	ENOG4105CSR	polyphosphate kinase 2
Tint_2639	ENOG4108NWD	Cytochrome
Tint_2640	ENOG4108RWI	nicotinamidase
Tint_2641	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Tint_2642	ENOG4108ESY	Metal dependent phosphohydrolase
Tint_2645	ENOG4108RC0	Electron transport protein
Tint_2646	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
Tint_2650	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Tint_2651	ENOG4105F2I	Transposase
Tint_2652	ENOG4105D2T	synthase
Tint_2653	ENOG4105F0R	Cytidylyltransferase
Tint_2656	ENOG4105D3Q	Sugar transferase
Tint_2659	ENOG4105DSY	exodeoxyribonuclease V, gamma
Tint_2660	ENOG4107QKA	exodeoxyribonuclease V beta
Tint_2661	ENOG4107QYX	exodeoxyribonuclease v alpha
Tint_2662	ENOG4108RRZ	Transcription elongation factor GreB
Tint_2663	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Tint_2664	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Tint_2665	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Tint_2666	ENOG4105DSJ	YicC domain protein
Tint_2669	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
Tint_2670	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Tint_2671	ENOG4105CSA	Coproporphyrinogen iii oxidase
Tint_2677	ENOG4108V1U	phospholipid-binding protein
Tint_2679	ENOG4105DHQ	Histidine kinase
Tint_2681	ENOG4105D64	Mechanosensitive ion channel
Tint_2685	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
Tint_2686	ENOG4105W3H	MtN3 and saliva related transmembrane protein
Tint_2688	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
Tint_2689	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Tint_2690	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
Tint_2693	ENOG4105CSR	polyphosphate kinase 2
Tint_2695	ENOG4108V0P	LemA family
Tint_2696	ENOG4105HA9	of methanol dehydrogenase type
Tint_2698	ENOG4108GAE	asmA family
Tint_2699	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
Tint_2700	ENOG4105T95	Thiol disulfide interChange protein
Tint_2705	ENOG4105CA0	peroxidase
Tint_2707	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Tint_2708	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
Tint_2711	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Tint_2712	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Tint_2713	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
Tint_2714	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Tint_2717	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
Tint_2721	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
Tint_2722	ENOG4105E39	Enoyl-CoA hydratase
Tint_2726	ENOG4107QX3	carboxylase
Tint_2727	ENOG4105CEY	Amp-dependent synthetase and ligase
Tint_2729	ENOG4105C1G	acyl-Coa dehydrogenase
Tint_2731	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
Tint_2732	ENOG4107STF	Involved in phosphonate degradation (By similarity)
Tint_2733	ENOG4105C1G	acyl-Coa dehydrogenase
Tint_2735	ENOG4108Z6Z	Transcriptional regulator
Tint_2736	ENOG4105C5X	domain protein
Tint_2738	ENOG4107QUT	magnesium and cobalt transport protein CorA
Tint_2740	ENOG41080IJ	Diacylglycerol kinase
Tint_2741	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Tint_2745	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Tint_2746	ENOG4108IUZ	ABC transporter
Tint_2747	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
Tint_2750	ENOG4105C75	arginyL-tRNA synthetase
Tint_2751	ENOG4105VIF	phosphate starvation-inducible protein
Tint_2753	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Tint_2754	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Tint_2755	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Tint_2757	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Tint_2758	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Tint_2759	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Tint_2760	ENOG4107RAZ	it plays a direct role in the translocation of protons across the membrane (By similarity)
Tint_2763	ENOG4105XA0	heptosyltransferase ii
Tint_2765	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Tint_2766	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
Tint_2768	ENOG4105D7Q	type ii secretion system
Tint_2769	ENOG4107QHF	type ii secretion system protein e
Tint_2774	ENOG4108RTD	type II secretion system protein K
Tint_2775	ENOG4108WWZ	General secretion pathway protein J
Tint_2778	ENOG4108VAU	general secretion pathway protein G
Tint_2782	ENOG4105C9M	aspartyl-trna synthetase
Tint_2783	ENOG4106H3A	restriction
Tint_2784	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
Tint_2786	ENOG4105CDA	abc transporter atp-binding protein
Tint_2788	ENOG4105CHM	Aminotransferase
Tint_2790	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
Tint_2794	ENOG4107QX9	Thiol disulfide interChange protein
Tint_2795	ENOG4105EJC	lysr family transcriptional regulator
Tint_2796	ENOG4107QP3	malate synthase g
Tint_2797	ENOG4105BZU	Histidine kinase
Tint_2798	ENOG4105EMU	Dehydrogenase
Tint_2800	ENOG4105MYN	Zinc uptake regulation protein
Tint_2802	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
Tint_2803	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Tint_2807	ENOG4105C3R	Methionine synthase
Tint_2808	ENOG4105BZS	acriflavin resistance protein
Tint_2809	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
Tint_2814	ENOG4105C0P	Mg chelatase subunit ChlI
Tint_2817	ENOG4108YZA	Nitrogen regulatory protein pii
Tint_2818	ENOG4105BZU	Histidine kinase
Tint_2824	ENOG4105D7Z	glutathione synthase
Tint_2826	ENOG4105D3R	alkyl hydroperoxide reductase
Tint_2829	ENOG4105DZQ	phospholipase D Transphosphatidylase
Tint_2832	ENOG41066VF	YeeE YedE family protein
Tint_2834	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Tint_2835	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Tint_2836	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Tint_2837	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
Tint_2839	ENOG4108Z9W	Outer membrane porin
Tint_2840	ENOG4108Z9W	Outer membrane porin
Tint_2841	ENOG4108UKZ	OsmC family
Tint_2843	ENOG4105W39	Membrane
Tint_2844	ENOG4105C7B	Threonine dehydratase
Tint_2849	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
Tint_2852	ENOG4105D94	Major Facilitator Superfamily
Tint_2853	ENOG4106NZI	LysR family Transcriptional regulator
Tint_2856	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
Tint_2857	ENOG4105QG4	Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde) (By similarity)
Tint_2858	ENOG41060W2	glyoxylate carboligase
Tint_2860	ENOG41084KP	4-oxalocrotonate tautomerase
Tint_2861	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
Tint_2862	ENOG4105CW7	secretion protein, HlyD family
Tint_2864	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Tint_2866	ENOG4105C3G	gtp-binding protein
Tint_2868	ENOG4105D82	Glutamate dehydrogenase
Tint_2869	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Tint_2870	ENOG41084PQ	50s ribosomal protein l29
Tint_2871	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Tint_2872	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Tint_2873	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Tint_2874	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Tint_2875	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Tint_2876	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Tint_2877	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Tint_2878	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Tint_2879	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Tint_2880	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Tint_2881	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Tint_2882	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Tint_2883	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Tint_2884	ENOG4105F0I	Aminotransferase
Tint_2885	ENOG4105WH1	Two component transcriptional regulator luxr family
Tint_2886	ENOG4105C9A	Phoh family
Tint_2887	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Tint_2888	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
Tint_2890	ENOG4107ZT5	Thiol disulfide interchange protein
Tint_2891	ENOG4105D2S	major facilitator superfamily
Tint_2895	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Tint_2898	ENOG410692J	cytochrome C, class I
Tint_2899	ENOG4107S7U	Sulfide dehydrogenase
Tint_2901	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Tint_2903	ENOG4105ES5	Histidine kinase
Tint_2913	ENOG4105KT5	UmuD protein
Tint_2915	ENOG4108F3G	Type I restriction-modification system, R subunit
Tint_2923	ENOG4108NF7	phage-type endonuclease
Tint_2929	ENOG4108P8R	
Tint_2937	ENOG41067CV	Integrase
Tint_2940	ENOG410807V	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
Tint_2942	ENOG4105DZ2	Transcriptional regulator
Tint_2943	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
Tint_2945	ENOG41066FR	extracellular solute-binding protein
Tint_2946	ENOG4105E0C	molybdate abc transporter
Tint_2947	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Tint_2948	ENOG4105F4R	Transcriptional regulator mode
Tint_2955	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Tint_2959	ENOG4105QAX	Iron-sulfur
Tint_2960	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Tint_2963	ENOG4105DF6	Fe-S oxidoreductase
Tint_2964	ENOG4105CSH	Transporter
Tint_2967	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
Tint_2970	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Tint_2972	ENOG4105MA0	exported protein
Tint_2977	ENOG4108K3A	Glutathione S-transferase
Tint_2979	ENOG4105EYM	Major Facilitator superfamily
Tint_2981	ENOG4105CPC	Aldo Keto reductase
Tint_2988	ENOG4108IV0	ABC, transporter
Tint_2989	ENOG4105C0Z	ABC transporter
Tint_2997	ENOG4105DXM	phenylacetic acid degradation protein
Tint_2998	ENOG4105CHU	acetyl-coa acetyltransferase
Tint_2999	ENOG4108IG5	Transcriptional regulator
Tint_3000	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
Tint_3001	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
Tint_3002	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
Tint_3003	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
Tint_3004	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
Tint_3006	ENOG4108ZJI	phenylacetic acid degradation protein
Tint_3007	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Tint_3008	ENOG4108UKI	Enoyl-CoA hydratase
Tint_3009	ENOG4108Z0R	Transferase
Tint_3010	ENOG4108IPT	Naphthoate synthase
Tint_3015	ENOG4106IJN	integrase catalytic domain-containing protein
Tint_3018	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
Tint_3023	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
Tint_3025	ENOG4105VV5	Plasmid stabilization system
Tint_3027	ENOG4105CAQ	asparagine synthetase
Tint_3036	ENOG4105CAU	Arsenical resistance protein, ArsH
Tint_3039	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Tint_3050	ENOG41061N2	exported protein
Tint_3054	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Tint_3056	ENOG4105DB1	molybdopterin oxidoreductase
Tint_3060	ENOG4105W2Z	cytochrome C, class I
Tint_3061	ENOG4108K28	Arsenite oxidase, large subunit
Tint_3062	ENOG41081YG	arsenite oxidase, small subunit
Tint_3066	ENOG4105E3B	Multicopper oxidase
Tint_3069	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Tint_3070	ENOG4105E0F	Histidine kinase
Tint_3073	ENOG4105F2I	Transposase
Tint_3074	ENOG4105D9G	High-affinity
Tint_3078	ENOG4108USZ	hydrogenase
Tint_3079	ENOG4105X9Y	Hydrogenase assembly chaperone hypC hupF
Tint_3080	ENOG4105YYZ	Hydrogenase expression formation protein
Tint_3082	ENOG4107UY0	rubredoxin
Tint_3085	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
Tint_3086	ENOG4107RSS	Hydrogenase accessory protein HypB
Tint_3090	ENOG4105DPX	Hydrogenase, large subunit
Tint_3091	ENOG4105C8H	hydrogenase maturation protein Hypf
Tint_3092	ENOG41082MF	Hydrogenase assembly chaperone hypC hupF
Tint_3093	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
Tint_3094	ENOG4105CQS	hydrogenase expression formation protein HypD
Tint_3095	ENOG4105C45	hydrogenase expression formation protein (HypE)
Tint_3103	ENOG4105VTR	Integrase
Tint_3105	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Tint_3106	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Tint_3107	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Tint_3108	ENOG4108VZM	50s ribosomal protein L10
Tint_3109	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Tint_3110	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Tint_3113	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Tint_3114	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Tint_3115	ENOG4107QYG	anthranilate phosphoribosyltransferase
Tint_3116	ENOG4105DDQ	anthranilate synthase
Tint_3121	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Tint_3122	ENOG4105DJV	ribulose-phosphate 3-epimerase
Tint_3123	ENOG4105NWN	ApaG protein
Tint_3125	ENOG4105CA3	membrane-bound lytic murein transglycosylase
Tint_3127	ENOG4105CKW	Inner membrane protein yedI
Tint_3128	ENOG4105EJ9	Membrane
Tint_3131	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
Tint_3132	ENOG4105C25	Primosomal protein n'
Tint_3134	ENOG4105C2C	drug resistance transporter, Bcr CflA
Tint_3137	ENOG4105CGZ	zinc metallopeptidase
Tint_3141	ENOG4108EC8	DNA internalization-related competence protein ComEC
Tint_3145	ENOG4105C3R	Methionine synthase
Tint_3148	ENOG41080T7	secreted protein
Tint_3149	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Tint_3152	ENOG4108XRS	Monoheme cytochrome SoxX (Sulfur oxidation)
Tint_3155	ENOG4105EUZ	Beta-lactamase domain protein
Tint_3156	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
Tint_3159	ENOG4105DFH	Transport of potassium into the cell (By similarity)
Tint_3160	ENOG4105D4P	Coproporphyrinogen iii oxidase
Tint_3161	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
Tint_3162	ENOG4105EJ9	Membrane
Tint_3166	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Tint_3167	ENOG4107QJE	Chromosome Partitioning Protein
Tint_3169	ENOG4105FA0	parb-like partition protein
Tint_3172	ENOG4105BZU	Histidine kinase
Tint_3180	ENOG4105DAA	L-lactate
Tint_3182	ENOG4105CXY	transporter
Tint_3186	ENOG41080HT	Transcriptional regulator, arsr family
Tint_3187	ENOG4108IV0	ABC, transporter
Tint_3188	ENOG4105C0Z	ABC transporter
Tint_3189	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Tint_3190	ENOG4105C32	Amino acid ABC transporter (Permease)
Tint_3193	ENOG4108JQ1	Dehydrogenase
Tint_3194	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Tint_3195	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Tint_3198	ENOG4105VG0	50S ribosomal protein l34
Tint_3212	ENOG4108C33	Resolvase
Tint_3213	ENOG4107SJW	iron permease, FTR1
Tint_3216	ENOG4105VUF	Transcriptional regulator
Tint_3219	ENOG4105J1P	transposase, IS3 IS911 family protein
Tint_3224	ENOG4105ESI	atpase involved in dna repair
Tint_3226	ENOG4105QHH	Antitoxin component of a toxin-antitoxin (TA) module. A labile antitoxin that counteracts the effect of the YafQ toxin. YafQ and DinJ together bind their own promoter, and by analogy to other TA modules probably repress its expression
Tint_3238	ENOG4105D13	transposase
Tint_3239	ENOG4108C33	Resolvase
Tint_3248	ENOG4108C33	Resolvase
Tint_3259	ENOG4108C33	Resolvase
Tint_3260	ENOG4105D13	transposase