locus-tag	class	description
THII_0001	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
THII_0018	ENOG4107VAM	peptidase, m28
THII_0019	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
THII_0020	ENOG4108HPI	phosphatidate Cytidylyltransferase
THII_0026	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
THII_0027	ENOG4105DB1	molybdopterin oxidoreductase
THII_0028	ENOG4105K64	Glycosyl transferase, family 2
THII_0029	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
THII_0032	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
THII_0034	ENOG4105CAT	Cytidine monophosphate kinase
THII_0035	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
THII_0036	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
THII_0037	ENOG4105CFV	Tetratricopeptide repeat protein
THII_0038	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
THII_0039	ENOG4107Y3D	HAD-superfamily hydrolase subfamily IA variant 3
THII_0041	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
THII_0047	ENOG4105CUZ	uba thif-type nad fad binding protein
THII_0048	ENOG4105F8V	Hydrolase, tatD family
THII_0050	ENOG4105BZU	Histidine kinase
THII_0055	ENOG4107T8Q	Glycosyl transferase (Group 1
THII_0057	ENOG4108VIA	integral membrane protein
THII_0058	ENOG4105II7	pyrroline-5-carboxylate reductase
THII_0062	ENOG4105D78	K07001 NTE family protein
THII_0065	ENOG4107QR8	Thioredoxin
THII_0067	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
THII_0068	ENOG4105EKE	dihydroorotase
THII_0070	ENOG4105BZU	Histidine kinase
THII_0071	ENOG4105D5K	Hemolysin activator protein
THII_0075	ENOG4107QX9	Thiol disulfide interChange protein
THII_0076	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
THII_0090	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
THII_0091	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
THII_0093	ENOG4105GJM	(LipO)protein
THII_0095	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
THII_0101	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
THII_0102	ENOG4105D4P	Coproporphyrinogen iii oxidase
THII_0104	ENOG4105CM2	brancheD-chain amino acid aminotransferase
THII_0106	ENOG4105XA0	heptosyltransferase ii
THII_0110	ENOG4108ZX6	Electron transport protein SCO1 SenC
THII_0119	ENOG41089UC	methyltransferase, type 11
THII_0124	ENOG4105C12	Phosphoribosylglycinamide synthetase
THII_0125	ENOG4105VZ9	UPF0235 protein
THII_0129	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
THII_0138	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
THII_0142	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
THII_0143	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
THII_0144	ENOG4105K70	DNA-binding protein
THII_0145	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
THII_0146	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
THII_0147	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
THII_0148	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
THII_0150	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
THII_0151	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
THII_0152	ENOG4105D52	delta-aminolevulinic acid dehydratase
THII_0154	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
THII_0155	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
THII_0157	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
THII_0163	ENOG4105D7V	transposase
THII_0176	ENOG4107QYX	exodeoxyribonuclease v alpha
THII_0177	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
THII_0180	ENOG4105K63	Thioredoxin
THII_0181	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
THII_0184	ENOG4105CHC	glucokinase (EC 2.7.1.2)
THII_0185	ENOG4107QJZ	Glycosyl transferase, family 2
THII_0191	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
THII_0192	ENOG4105MFV	ABC-2 type transporter
THII_0195	ENOG4107YV9	domain protein
THII_0196	ENOG4105CFH	Aspartokinase
THII_0197	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
THII_0199	ENOG4108EC8	DNA internalization-related competence protein ComEC
THII_0201	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
THII_0202	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
THII_0204	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
THII_0209	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
THII_0213	ENOG4105EY8	ABC transporter
THII_0214	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
THII_0216	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
THII_0217	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
THII_0223	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
THII_0231	ENOG41067TZ	transcriptional regulator, MarR family
THII_0233	ENOG4105CJP	fad dependent oxidoreductase
THII_0242	ENOG4105CBD	Diacylglycerol kinase
THII_0243	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
THII_0246	ENOG4108ISG	Major Facilitator
THII_0248	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
THII_0249	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
THII_0250	ENOG4105E07	UPF0149 protein
THII_0251	ENOG4107RAQ	aminopeptidase
THII_0257	ENOG4105C5F	glutamine synthetase
THII_0260	ENOG4108U5Y	In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the major outer membrane porin. It has been described in publications as the Sarkosyl- insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan
THII_0261	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
THII_0262	ENOG4108Z03	MAF-like protein
THII_0266	ENOG4105E54	alpha-amylase
THII_0267	ENOG4105BZU	Histidine kinase
THII_0268	ENOG4105BZU	Histidine kinase
THII_0270	ENOG4105W2Z	cytochrome C, class I
THII_0271	ENOG4107QY8	reductase
THII_0286	ENOG4105C30	Nad-dependent epimerase dehydratase
THII_0287	ENOG4108ZT0	50S ribosomal protein l17
THII_0288	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
THII_0289	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
THII_0290	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
THII_0291	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
THII_0292	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
THII_0293	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
THII_0294	ENOG4105VPB	50S ribosomal protein L30
THII_0295	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
THII_0296	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
THII_0297	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
THII_0298	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
THII_0299	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
THII_0300	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
THII_0301	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
THII_0302	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
THII_0304	ENOG41083MP	50s ribosomal protein l29
THII_0305	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
THII_0306	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
THII_0307	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
THII_0308	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
THII_0309	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
THII_0310	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
THII_0311	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
THII_0312	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
THII_0313	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
THII_0314	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
THII_0315	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
THII_0316	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
THII_0317	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
THII_0322	ENOG4105CK7	Sodium proline symporter
THII_0324	ENOG41085AF	Cytochrome
THII_0330	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
THII_0331	ENOG4105BZU	Histidine kinase
THII_0334	ENOG4108VKQ	nitriC oxide reductase
THII_0335	ENOG4105DSQ	Nitric oxide reductase
THII_0347	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
THII_0348	ENOG4105D6Z	AFG1 family ATPase
THII_0349	ENOG4105VN1	Heat shock protein
THII_0350	ENOG4105BZU	Histidine kinase
THII_0351	ENOG4105DWY	Agmatine deiminase
THII_0354	ENOG4105BZU	Histidine kinase
THII_0355	ENOG4107S78	Band 7 protein
THII_0356	ENOG4105PV3	Inner membrane protein yqiJ
THII_0360	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
THII_0361	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
THII_0363	ENOG4105FAE	von Willebrand factor, type A
THII_0365	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
THII_0366	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
THII_0367	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
THII_0379	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
THII_0383	ENOG4105FDK	ABC transporter
THII_0384	ENOG4105FAV	ABC, transporter
THII_0388	ENOG4105CKI	cobalamin synthesis protein
THII_0393	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
THII_0407	ENOG4105CQ7	ATP-dependent helicase
THII_0410	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
THII_0411	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
THII_0414	ENOG4108UB4	uncharacterized protein ygjQ
THII_0416	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
THII_0417	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
THII_0418	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
THII_0419	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
THII_0420	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
THII_0421	ENOG4105DHT	Metal Dependent Phosphohydrolase
THII_0423	ENOG4107QHF	type ii secretion system protein e
THII_0425	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
THII_0426	ENOG4105KK6	nuclease
THII_0431	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
THII_0433	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
THII_0435	ENOG4105DSB	aldose 1-epimerase
THII_0436	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
THII_0443	ENOG4105BZU	Histidine kinase
THII_0444	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THII_0445	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THII_0446	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
THII_0461	ENOG4106IPI	cyclase, family
THII_0463	ENOG4105C6K	Malic enzyme
THII_0464	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
THII_0470	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
THII_0473	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
THII_0474	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
THII_0475	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
THII_0482	ENOG4105E0Y	RtcB Protein
THII_0485	ENOG4105C19	ABC transporter
THII_0487	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
THII_0488	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
THII_0491	ENOG4108ZX6	Electron transport protein SCO1 SenC
THII_0492	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THII_0496	ENOG4108RS6	transposase
THII_0500	ENOG4105BZU	Histidine kinase
THII_0503	ENOG4105CJ2	(LipO)protein
THII_0512	ENOG4105CDY	transcriptional regulatory protein
THII_0513	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
THII_0515	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
THII_0517	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
THII_0518	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THII_0520	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THII_0527	ENOG4107QIZ	NADH dehydrogenase
THII_0534	ENOG4107QP3	malate synthase g
THII_0535	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THII_0538	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
THII_0541	ENOG4105BZU	Histidine kinase
THII_0543	ENOG4105CM6	amino acid regulated cytosolic protein
THII_0549	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
THII_0550	ENOG4105BZU	Histidine kinase
THII_0552	ENOG4105C8Q	Methyl-accepting chemotaxis
THII_0553	ENOG4108V3W	Chemotaxis protein, CheW
THII_0554	ENOG4105CBS	Chea signal transduction histidine kinase
THII_0555	ENOG4108VYJ	response regulator receiver protein
THII_0558	ENOG4105CAS	nag kinase
THII_0559	ENOG4105Y75	tpr repeat protein
THII_0561	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
THII_0562	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
THII_0568	ENOG41071TK	Uncharacterised protein family (UPF0150)
THII_0571	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
THII_0579	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
THII_0584	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
THII_0586	ENOG4105FIE	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) (By similarity)
THII_0592	ENOG4105F71	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
THII_0593	ENOG4105D6S	protein involved in catabolism of external DNA
THII_0594	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
THII_0595	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
THII_0596	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
THII_0603	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
THII_0604	ENOG4105KPY	Small multidrug resistance protein
THII_0605	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
THII_0611	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
THII_0612	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
THII_0613	ENOG4108ZAT	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE (By similarity)
THII_0614	ENOG4108ZKU	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions (By similarity)
THII_0616	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
THII_0619	ENOG4105BZ8	glutamate synthase
THII_0621	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
THII_0623	ENOG4108I0Q	anthranilate phosphoribosyltransferase
THII_0634	ENOG4107QKA	exodeoxyribonuclease V beta
THII_0636	ENOG4105BZU	Histidine kinase
THII_0637	ENOG4105CPK	Glycosyl transferase (Group 1
THII_0638	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
THII_0640	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
THII_0641	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
THII_0644	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
THII_0646	ENOG4105CD3	dihydroorotase
THII_0647	ENOG4105CXT	aspartate transcarbamylase
THII_0648	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
THII_0649	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
THII_0650	ENOG4108UJU	UPF0301 protein
THII_0655	ENOG4106R49	Methyltransferase
THII_0657	ENOG4105CVI	Transcriptional regulator
THII_0658	ENOG4105CZX	twitching motility protein
THII_0659	ENOG4105CZX	twitching motility protein
THII_0660	ENOG4105CZX	twitching motility protein
THII_0662	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
THII_0663	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
THII_0667	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
THII_0669	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
THII_0670	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
THII_0673	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
THII_0674	ENOG4105CEY	Amp-dependent synthetase and ligase
THII_0681	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
THII_0682	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
THII_0686	ENOG4108NEV	two component transcriptional regulator, LytTR family
THII_0694	ENOG4105DFU	Cell wall formation (By similarity)
THII_0695	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
THII_0699	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
THII_0701	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
THII_0703	ENOG4107FQX	Alpha-acetolactate decarboxylase
THII_0704	ENOG4107FQX	Alpha-acetolactate decarboxylase
THII_0707	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
THII_0708	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
THII_0709	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
THII_0712	ENOG4105C8Y	Acetylornithine aminotransferase
THII_0713	ENOG4105DBV	ornithine carbamoyltransferase
THII_0726	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
THII_0727	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
THII_0729	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
THII_0736	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
THII_0737	ENOG4108IAJ	Nad-dependent epimerase dehydratase
THII_0738	ENOG4105CKK	Glycosyl transferase, family 2
THII_0739	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
THII_0740	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
THII_0743	ENOG4105D9R	oxidoreductase
THII_0747	ENOG4106H78	methyltransferase
THII_0748	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
THII_0750	ENOG4105BZU	Histidine kinase
THII_0751	ENOG4105BZU	Histidine kinase
THII_0752	ENOG4105CH7	arginosuccinase
THII_0754	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
THII_0760	ENOG4105C3Q	Glycosyl transferase, family 2
THII_0762	ENOG4105BZ1	(ABC) transporter
THII_0764	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
THII_0765	ENOG4105KCK	Peptidoglycan-associated lipoprotein
THII_0767	ENOG4108K5H	permease YjgP YjgQ family protein
THII_0770	ENOG4105CJE	phosphoribulokinase (EC 2.7.1.19)
THII_0772	ENOG4105F8C	transglutaminase domain-containing protein
THII_0774	ENOG4105BZU	Histidine kinase
THII_0775	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THII_0777	ENOG4105BZU	Histidine kinase
THII_0780	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
THII_0781	ENOG4105CAK	Cell division ATP-binding protein ftsE
THII_0782	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
THII_0784	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
THII_0785	ENOG4105CV1	Transketolase (EC 2.2.1.1)
THII_0792	ENOG41067QW	Transcriptional regulator
THII_0795	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
THII_0799	ENOG4105DAY	polysaccharide export protein
THII_0802	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
THII_0803	ENOG4105BZU	Histidine kinase
THII_0805	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
THII_0806	ENOG4105D0A	hydroxylase
THII_0808	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
THII_0814	ENOG41087AY	ADP-Ribose pyrophosphatase
THII_0816	ENOG4105E18	UPF0276 protein
THII_0821	ENOG4105MA0	exported protein
THII_0823	ENOG410811H	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
THII_0824	ENOG4105C3R	Methionine synthase
THII_0829	ENOG4106WTF	Glycosyl transferase, family 2
THII_0834	ENOG4105CK2	sodium dicarboxylate symporter
THII_0835	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
THII_0837	ENOG4105CHR	reductase
THII_0839	ENOG4105CHU	acetyl-coa acetyltransferase
THII_0841	ENOG4105C47	NADH ubiquinone oxidoreductase 20 kda subunit
THII_0842	ENOG4105C0D	helicase
THII_0845	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
THII_0846	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
THII_0847	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
THII_0850	ENOG4105KB2	stringent starvation protein b
THII_0851	ENOG4105EIX	cytochrome c1
THII_0852	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
THII_0853	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
THII_0854	ENOG4105GVR	general secretion pathway protein D
THII_0856	ENOG4108VAU	general secretion pathway protein G
THII_0862	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
THII_0863	ENOG4105E66	phosphoriboisomerase A
THII_0864	ENOG41082YX	Transcriptional regulator, arsr family
THII_0865	ENOG4105D6J	arsenicaL-resistance protein
THII_0866	ENOG4107S21	permease
THII_0868	ENOG4108UXE	Protein tyrosine phosphatase
THII_0872	ENOG4108HMN	Caspase domain
THII_0875	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
THII_0877	ENOG4105BZU	Histidine kinase
THII_0878	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
THII_0881	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
THII_0886	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
THII_0891	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
THII_0903	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
THII_0914	ENOG4108JPZ	Monovalent cation H antiporter subunit D
THII_0915	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THII_0919	ENOG4105BZU	Histidine kinase
THII_0920	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
THII_0921	ENOG4105BZU	Histidine kinase
THII_0927	ENOG4105CBG	Sulfatase
THII_0928	ENOG4105W5Q	DNA repair protein (RadC
THII_0929	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
THII_0931	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
THII_0936	ENOG4108TIT	dATP pyrophosphohydrolase
THII_0937	ENOG4105BZU	Histidine kinase
THII_0938	ENOG4106R49	Methyltransferase
THII_0939	ENOG4105DJ4	phosphatidylserine decarboxylase
THII_0940	ENOG4105E9H	Lytic Murein transglycosylase
THII_0943	ENOG4105WH1	Two component transcriptional regulator luxr family
THII_0944	ENOG4105BZU	Histidine kinase
THII_0949	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
THII_0950	ENOG4105C8Q	Methyl-accepting chemotaxis
THII_0951	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
THII_0952	ENOG4105E2X	shikimate dehydrogenase
THII_0961	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
THII_0968	ENOG4105BZU	Histidine kinase
THII_0971	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
THII_0972	ENOG4105D16	lipopolysaccharide heptosyltransferase i
THII_0973	ENOG4105FE9	pseudouridine synthase
THII_0980	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
THII_0981	ENOG4105VTW	prevent-host-death family
THII_0982	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
THII_0983	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
THII_0984	ENOG4108ZCA	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
THII_0985	ENOG4105EU8	FAD linked oxidase domain protein
THII_0993	ENOG4108UK5	Transposase
THII_0999	ENOG4105CS6	Rhs element vgr protein
THII_1001	ENOG4108MBK	is1 orf2
THII_1016	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
THII_1019	ENOG4105BZU	Histidine kinase
THII_1020	ENOG4105BZU	Histidine kinase
THII_1021	ENOG4105BZU	Histidine kinase
THII_1025	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
THII_1026	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
THII_1027	ENOG4105DR5	peptidase
THII_1029	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
THII_1031	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
THII_1032	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
THII_1034	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
THII_1036	ENOG4105BZU	Histidine kinase
THII_1037	ENOG4105BZU	Histidine kinase
THII_1038	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
THII_1039	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
THII_1040	ENOG4105D4Y	metalloprotease
THII_1046	ENOG4108UVJ	appr-1-p processing domain protein
THII_1051	ENOG4105DXX	methyltransferase
THII_1057	ENOG4107RIQ	Sulfate adenylate transferase
THII_1070	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
THII_1083	ENOG41060A7	DNA polymerase beta domain protein region
THII_1084	ENOG41062MS	nucleotidyltransferase substrate binding protein
THII_1091	ENOG4105CKK	Glycosyl transferase, family 2
THII_1100	ENOG4105CD5	CoA-binding domain protein
THII_1103	ENOG4108UK5	Transposase
THII_1110	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
THII_1112	ENOG4105CKK	Glycosyl transferase, family 2
THII_1122	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THII_1126	ENOG4108M24	von Willebrand factor, type A
THII_1130	ENOG4105BZU	Histidine kinase
THII_1131	ENOG4105BZU	Histidine kinase
THII_1133	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
THII_1134	ENOG4108SVW	integral membrane protein
THII_1142	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
THII_1151	ENOG4105CJW	magnesium transporter
THII_1153	ENOG4105I7R	Adenylate cyclase
THII_1154	ENOG4108DN8	FAD dependent oxidoreductase
THII_1158	ENOG4105C0P	Mg chelatase subunit ChlI
THII_1159	ENOG4105W0Z	cytoplasmic protein
THII_1160	ENOG4105WPN	DNA integration recombination invertion protein
THII_1161	ENOG4105BZU	Histidine kinase
THII_1164	ENOG4105M15	transport protein ExbD
THII_1165	ENOG4105M8K	biopolymer transport protein
THII_1168	ENOG4105GAV	receptor
THII_1173	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
THII_1175	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
THII_1176	ENOG4105CHV	Transcription elongation factor NusA
THII_1177	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
THII_1178	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
THII_1179	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
THII_1180	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
THII_1181	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
THII_1191	ENOG4105BZU	Histidine kinase
THII_1195	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
THII_1196	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
THII_1197	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
THII_1199	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
THII_1202	ENOG4105E6M	Sulphatase-modifying factor protein
THII_1204	ENOG4105E0C	molybdate abc transporter
THII_1205	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
THII_1208	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
THII_1209	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
THII_1210	ENOG4105VIE	preprotein translocase, subunit YajC
THII_1211	ENOG4105VFB	Binds the 23S rRNA (By similarity)
THII_1212	ENOG4105C6T	cysteine synthase
THII_1214	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
THII_1217	ENOG4105C9U	ATP-dependent DNA helicase RecQ
THII_1219	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
THII_1227	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
THII_1233	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
THII_1235	ENOG4105D17	glycoside hydrolase, family 3 domain protein
THII_1238	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
THII_1239	ENOG4105C2N	RNA methyltransferase TrmH family group 3
THII_1243	ENOG4105BZU	Histidine kinase
THII_1245	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
THII_1249	ENOG4105C7B	Threonine dehydratase
THII_1250	ENOG4107YRI	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
THII_1251	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
THII_1252	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
THII_1253	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
THII_1254	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THII_1255	ENOG4108IUZ	ABC transporter
THII_1256	ENOG4105WI0	lipopolysaccharide transport periplasmic protein lptA
THII_1258	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
THII_1259	ENOG4105C2X	Arabinose 5-phosphate isomerase
THII_1268	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
THII_1269	ENOG41072GX	Peptidase M22 Glycoprotease
THII_1270	ENOG4105C2M	dna polymerase I
THII_1275	ENOG4105CMR	udp-glucose 4-epimerase
THII_1276	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
THII_1277	ENOG4105E4C	Lytic transglycosylase catalytic
THII_1278	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
THII_1283	ENOG4105CBS	Chea signal transduction histidine kinase
THII_1285	ENOG4105C8Q	Methyl-accepting chemotaxis
THII_1286	ENOG4108ZGA	chew protein
THII_1287	ENOG4105M3Z	response regulator
THII_1288	ENOG4108UNF	response regulator
THII_1296	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
THII_1297	ENOG4105C28	cystathionine
THII_1299	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
THII_1301	ENOG4105BZU	Histidine kinase
THII_1302	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
THII_1305	ENOG4108M8S	permease YjgP YjgQ family protein
THII_1306	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
THII_1311	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
THII_1314	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
THII_1317	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
THII_1319	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
THII_1320	ENOG41082RQ	UPF0102 protein
THII_1324	ENOG4105E4C	Lytic transglycosylase catalytic
THII_1325	ENOG4105D0M	Protease HtpX homolog
THII_1328	ENOG4107RDB	Major Facilitator
THII_1329	ENOG4108UUM	single-stranded DNA-binding protein
THII_1330	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
THII_1331	ENOG4107RZZ	dna polymerase iii epsilon subunit
THII_1332	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
THII_1333	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
THII_1334	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
THII_1336	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
THII_1338	ENOG4105K59	histidine triad (HIT) protein
THII_1339	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
THII_1340	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
THII_1341	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
THII_1345	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
THII_1346	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
THII_1347	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
THII_1364	ENOG4105BZU	Histidine kinase
THII_1365	ENOG4105BZU	Histidine kinase
THII_1366	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THII_1368	ENOG4105CTB	Polyprenyl synthetase
THII_1376	ENOG4105CH6	catalase
THII_1378	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
THII_1379	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
THII_1380	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
THII_1381	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
THII_1382	ENOG4108UB3	Thiamine monophosphate
THII_1384	ENOG4105CKK	Glycosyl transferase, family 2
THII_1392	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
THII_1393	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
THII_1395	ENOG4105BZU	Histidine kinase
THII_1396	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THII_1397	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
THII_1398	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
THII_1400	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
THII_1401	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
THII_1404	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
THII_1406	ENOG4105C1J	atp-dependent rna helicase
THII_1411	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
THII_1412	ENOG4105Y3E	Modulates RecA activity (By similarity)
THII_1413	ENOG4107KFM	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
THII_1420	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
THII_1424	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
THII_1425	ENOG4105KJF	protein tyrosine phosphatase
THII_1426	ENOG4105W49	UPF0434 protein
THII_1427	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
THII_1428	ENOG4109015	Biopolymer transport protein exbD tolR
THII_1430	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
THII_1431	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
THII_1435	ENOG4106R49	Methyltransferase
THII_1438	ENOG4105C9M	aspartyl-trna synthetase
THII_1441	ENOG4107QP8	phosphohexose isomerase
THII_1444	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
THII_1445	ENOG4105C26	Dehydrogenase
THII_1457	ENOG410902C	phosphohistidine phosphatase, SixA
THII_1458	ENOG4105CGK	Exodeoxyribonuclease III
THII_1460	ENOG4105C1V	Peptidase, M16
THII_1461	ENOG4105MJ2	Competence protein
THII_1463	ENOG4105EGS	Mechanosensitive ion channel
THII_1465	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
THII_1466	ENOG4105DZA	Converts GTP to 7,8-dihydroneopterin triphosphate (By similarity)
THII_1467	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
THII_1471	ENOG4108WWZ	General secretion pathway protein J
THII_1472	ENOG41080RH	Thioredoxin
THII_1473	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
THII_1475	ENOG4108TEB	UPF0114 protein
THII_1487	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
THII_1488	ENOG4107YYJ	Glycosyl transferase, family 2
THII_1489	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
THII_1490	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
THII_1493	ENOG4105M2J	Glutaredoxin
THII_1495	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
THII_1500	ENOG4105CA0	peroxidase
THII_1503	ENOG4108JJ7	ABC transporter
THII_1512	ENOG4105ERG	peptidase m48, ste24p
THII_1514	ENOG4105BZU	Histidine kinase
THII_1517	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THII_1520	ENOG4108UK5	Transposase
THII_1525	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
THII_1528	ENOG4105M8F	Biopolymer transport protein exbD tolR
THII_1529	ENOG4105E02	MotA TolQ exbB proton channel
THII_1530	ENOG4107YD3	Thioesterase
THII_1531	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
THII_1532	ENOG4106RE7	Cytochrome
THII_1533	ENOG4108Z33	Thiol disulfide Interchange Protein
THII_1536	ENOG4105KME	endoribonuclease L-psp
THII_1537	ENOG4105CB5	ATP-dependent DNA helicase recG
THII_1539	ENOG4105D3Q	Sugar transferase
THII_1540	ENOG4105BZU	Histidine kinase
THII_1542	ENOG4105CK7	Sodium proline symporter
THII_1543	ENOG4105C34	Pseudouridine synthase
THII_1544	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
THII_1546	ENOG4105DGW	oligopeptidase A
THII_1547	ENOG4107QQN	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
THII_1548	ENOG4108JPZ	Monovalent cation H antiporter subunit D
THII_1549	ENOG4107TDF	Formate hydrogenlyase subunit 4
THII_1554	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
THII_1562	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
THII_1563	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
THII_1564	ENOG4105DJ0	Poly(A) Polymerase
THII_1565	ENOG4105KDC	50s ribosomal protein l28
THII_1567	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
THII_1568	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
THII_1569	ENOG4106R49	Methyltransferase
THII_1570	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
THII_1571	ENOG4105C08	Histidine kinase
THII_1575	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
THII_1576	ENOG4105ECP	epimerase
THII_1585	ENOG4105BZU	Histidine kinase
THII_1592	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
THII_1595	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
THII_1599	ENOG4105CUV	Homoserine Kinase
THII_1600	ENOG4108URH	decarboxylase
THII_1602	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
THII_1605	ENOG4108JJA	ABC, transporter
THII_1615	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
THII_1618	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
THII_1619	ENOG4105D22	carbon starvation protein
THII_1624	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
THII_1625	ENOG4105EB3	Histidine kinase
THII_1629	ENOG4105UYK	outer membrane protein a
THII_1631	ENOG4105BZU	Histidine kinase
THII_1632	ENOG4105F8J	Adenylate Guanylate cyclase
THII_1633	ENOG4105DC1	bifunctional purine biosynthesis protein purh
THII_1634	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
THII_1646	ENOG4105D4A	Cell wall formation (By similarity)
THII_1649	ENOG4105CMR	udp-glucose 4-epimerase
THII_1658	ENOG41090RK	glycosyl transferase
THII_1663	ENOG4105CJ1	ABC, transporter
THII_1664	ENOG4105BZ1	(ABC) transporter
THII_1685	ENOG4106KVJ	cytochrome C assembly protein
THII_1691	ENOG4107S7U	Sulfide dehydrogenase
THII_1692	ENOG4105MW3	Cytochrome
THII_1694	ENOG4105CUW	cytochrome C-TYPE protein
THII_1695	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
THII_1696	ENOG4105FAW	cDP-glucose 4,6-dehydratase
THII_1698	ENOG4108SMP	Nad-dependent epimerase dehydratase
THII_1699	ENOG4108IAJ	Nad-dependent epimerase dehydratase
THII_1701	ENOG4105K64	Glycosyl transferase, family 2
THII_1707	ENOG4108SHN	Glycosyl transferase, family 2
THII_1709	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
THII_1710	ENOG4108UW5	maltose o-acetyltransferase
THII_1711	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
THII_1714	ENOG4106CD9	glycosyl transferase group 1
THII_1716	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
THII_1717	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
THII_1720	ENOG4105C3M	thioredoxin reductase
THII_1721	ENOG4105D7Q	type ii secretion system
THII_1734	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
THII_1735	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
THII_1736	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
THII_1739	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
THII_1741	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
THII_1742	ENOG4105KNE	Phosphatidate cytidylyltransferase
THII_1743	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
THII_1744	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
THII_1745	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
THII_1746	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
THII_1747	ENOG4105CE9	30S ribosomal protein S2
THII_1748	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
THII_1749	ENOG4105D06	uba thif-type nad fad binding protein
THII_1750	ENOG4105M00	molybdopterin converting factor, subunit 1
THII_1751	ENOG4108ZAF	Molybdopterin
THII_1754	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
THII_1755	ENOG4105D06	uba thif-type nad fad binding protein
THII_1756	ENOG4105EIF	outer membrane protein W
THII_1761	ENOG4105EIN	peptidylprolyl cis-trans isomerase
THII_1764	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
THII_1765	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
THII_1767	ENOG4105FQT	
THII_1770	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
THII_1772	ENOG4105CJR	Integral membrane protein (MviN
THII_1773	ENOG4105DTN	riboflavin biosynthesis protein ribF
THII_1777	ENOG4105BZU	Histidine kinase
THII_1781	ENOG4105KH3	nitrite reductase (NAD(P)h) small subunit
THII_1782	ENOG4108IFG	nitrite reductase, (NAD(P)H)
THII_1783	ENOG4107RNU	major facilitator superfamily MFS_1
THII_1789	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
THII_1790	ENOG4105EHG	Permease protein
THII_1794	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
THII_1796	ENOG4108JU5	Magnesium and cobalt efflux protein
THII_1797	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
THII_1798	ENOG4105C9A	Phoh family
THII_1799	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
THII_1801	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
THII_1804	ENOG4105C25	Primosomal protein n'
THII_1806	ENOG4105DSM	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein (By similarity)
THII_1807	ENOG4105D0B	Nitrogenase protein alpha chain
THII_1808	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
THII_1810	ENOG4107IVC	4Fe-4S ferredoxin, iron-sulfur binding
THII_1811	ENOG4105FZE	dinitrogenase iron-molybdenum cofactor biosynthesis
THII_1813	ENOG4105D0B	Nitrogenase protein alpha chain
THII_1814	ENOG4105DK8	Nitrogenase molybdenum-iron cofactor biosynthesis protein NifN
THII_1815	ENOG4108UR2	Nitrogen fixation protein NifX
THII_1818	ENOG4105WCA	Ferredoxin
THII_1823	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
THII_1825	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
THII_1828	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
THII_1829	ENOG4105CZX	twitching motility protein
THII_1831	ENOG4108RS6	transposase
THII_1832	ENOG4105CIH	Imidazole acetol-phosphate transaminase
THII_1834	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
THII_1836	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
THII_1837	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
THII_1847	ENOG4105BZU	Histidine kinase
THII_1848	ENOG4108Z0T	Part of a sulfur-relay system (By similarity)
THII_1849	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THII_1852	ENOG4105C8T	Leucyl-tRNA synthetase
THII_1862	ENOG4107QIJ	Aconitate hydratase 2
THII_1870	ENOG4105DXN	mazG family
THII_1875	ENOG4107T6J	Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit
THII_1876	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
THII_1878	ENOG4105CFU	surface antigen
THII_1880	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
THII_1881	ENOG4105NBF	ammecr1 domain protein
THII_1882	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
THII_1884	ENOG4105BZU	Histidine kinase
THII_1887	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
THII_1888	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
THII_1889	ENOG4105C5R	Aminotransferase
THII_1904	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
THII_1905	ENOG4105VCC	30S ribosomal protein S21
THII_1907	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
THII_1908	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THII_1909	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
THII_1912	ENOG4108SHN	Glycosyl transferase, family 2
THII_1913	ENOG4105BZU	Histidine kinase
THII_1915	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
THII_1917	ENOG4105C5H	ABC transporter
THII_1919	ENOG4106C6A	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
THII_1920	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
THII_1921	ENOG41060IM	Heme exporter protein
THII_1923	ENOG4105BZ4	penicillin-binding protein
THII_1924	ENOG4105C8Q	Methyl-accepting chemotaxis
THII_1926	ENOG4108KTQ	Methyltransferase
THII_1928	ENOG4105CBS	Chea signal transduction histidine kinase
THII_1929	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
THII_1930	ENOG4105F8J	Adenylate Guanylate cyclase
THII_1945	ENOG4108UK5	Transposase
THII_1949	ENOG4105BZU	Histidine kinase
THII_1951	ENOG4105BZU	Histidine kinase
THII_1954	ENOG4105BZU	Histidine kinase
THII_1956	ENOG4105BZU	Histidine kinase
THII_1957	ENOG4105CNU	cell division protein FtsK
THII_1959	ENOG41089UC	methyltransferase, type 11
THII_1960	ENOG4105NWN	ApaG protein
THII_1962	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
THII_1963	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
THII_1969	ENOG4105DA5	(ABC) transporter
THII_1974	ENOG4105UYK	outer membrane protein a
THII_1977	ENOG4105DDQ	anthranilate synthase
THII_1978	ENOG4107QHF	type ii secretion system protein e
THII_1981	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
THII_1982	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
THII_1983	ENOG4108UNF	response regulator
THII_1984	ENOG4108UNF	response regulator
THII_1986	ENOG4108V3W	Chemotaxis protein, CheW
THII_1987	ENOG4105C8Q	Methyl-accepting chemotaxis
THII_1988	ENOG4105CBS	Chea signal transduction histidine kinase
THII_1991	ENOG41065RQ	ADP-ribosylation crystallin J1
THII_2000	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
THII_2002	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
THII_2036	ENOG41060A7	DNA polymerase beta domain protein region
THII_2042	ENOG4108IMY	Transcriptional regulator
THII_2048	ENOG4105NDH	peptidase s1 and s6 chymotrypsin hap
THII_2050	ENOG4108JA2	transcriptioN-repair coupling factor
THII_2051	ENOG4105FFN	Specifically methylates the guanosine in position 1516 of 16S rRNA (By similarity)
THII_2056	ENOG4105E4C	Lytic transglycosylase catalytic
THII_2057	ENOG4106D4I	domain protein
THII_2061	ENOG4107VRP	DNA repair exonuclease
THII_2067	ENOG4105D1S	lipid A biosynthesis
THII_2069	ENOG4105D7Q	type ii secretion system
THII_2075	ENOG4108VAU	general secretion pathway protein G
THII_2077	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
THII_2078	ENOG4105DFH	Transport of potassium into the cell (By similarity)
THII_2081	ENOG4105D7Z	glutathione synthase
THII_2082	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
THII_2083	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
THII_2084	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
THII_2085	ENOG4108UNF	response regulator
THII_2090	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
THII_2102	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
THII_2103	ENOG4105EIN	peptidylprolyl cis-trans isomerase
THII_2104	ENOG4105M85	Bola protein
THII_2105	ENOG4105K9H	YciI-like protein
THII_2106	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
THII_2107	ENOG4107835	probably involved in intracellular septation (By similarity)
THII_2109	ENOG4105DHJ	ABC, transporter
THII_2110	ENOG4105CY3	ABC transporter, permease
THII_2112	ENOG4105SG9	biopolymer transport protein, ExbD
THII_2114	ENOG4108UJD	30S ribosomal protein S9
THII_2115	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
THII_2118	ENOG4105ECY	inositol monophosphatase
THII_2119	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
THII_2120	ENOG4108HMN	Caspase domain
THII_2123	ENOG4105CEY	Amp-dependent synthetase and ligase
THII_2127	ENOG4105VUH	addiction module killer protein
THII_2128	ENOG4105YES	addiction module antidote protein
THII_2132	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
THII_2136	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
THII_2139	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
THII_2161	ENOG4108UQQ	Electron transport complex
THII_2162	ENOG4105D6A	Electron transport complex
THII_2164	ENOG4108R3D	Electron transport complex
THII_2165	ENOG4105DGN	Electron transport complex
THII_2166	ENOG4105CS1	NAD(P)H quinone oxidoreductase
THII_2168	ENOG4105BZU	Histidine kinase
THII_2169	ENOG4105BZU	Histidine kinase
THII_2170	ENOG410829W	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
THII_2171	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
THII_2172	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
THII_2173	ENOG4105DFG	type I secretion outer membrane protein
THII_2174	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
THII_2175	ENOG4105C8Q	Methyl-accepting chemotaxis
THII_2176	ENOG4108V3W	Chemotaxis protein, CheW
THII_2177	ENOG4105CBS	Chea signal transduction histidine kinase
THII_2179	ENOG4107QRG	dna polymerase iii
THII_2181	ENOG4105F8V	Hydrolase, tatD family
THII_2184	ENOG4108S0N	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol (By similarity)
THII_2185	ENOG4105VEJ	Heat shock protein
THII_2188	ENOG4105C8Q	Methyl-accepting chemotaxis
THII_2194	ENOG41062T2	Acyl carrier protein
THII_2199	ENOG4108MBK	is1 orf2
THII_2201	ENOG4105C0W	non-ribosomal peptide synthetase
THII_2202	ENOG4105C0W	non-ribosomal peptide synthetase
THII_2202	ENOG4105C0W	non-ribosomal peptide synthetase
THII_2204	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
THII_2206	ENOG4105C1G	acyl-Coa dehydrogenase
THII_2208	ENOG4107SQU	synthase
THII_2209	ENOG4105C0W	non-ribosomal peptide synthetase
THII_2215	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
THII_2217	ENOG4108MH3	Polyketide beta-ketoacyl acyl carrier protein synthase
THII_2219	ENOG4105F99	Hydroxymethylglutaryl-CoA synthase
THII_2220	ENOG4108MGH	Enoyl-CoA hydratase
THII_2244	ENOG4105C59	p-type ATPase
THII_2258	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
THII_2261	ENOG4105GVR	general secretion pathway protein D
THII_2262	ENOG4105D7Q	type ii secretion system
THII_2263	ENOG4107QHF	type ii secretion system protein e
THII_2265	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
THII_2275	ENOG4105D1Z	hydroxypyruvate reductase
THII_2277	ENOG4105EWK	phytoene
THII_2278	ENOG4105EWK	phytoene
THII_2279	ENOG4105E33	succinate dehydrogenase
THII_2280	ENOG41086B8	CoB-CoM heterodisulfide reductase
THII_2288	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
THII_2289	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
THII_2294	ENOG4105BZU	Histidine kinase
THII_2295	ENOG4107Z5C	methylesterase
THII_2296	ENOG4105BZU	Histidine kinase
THII_2300	ENOG4105CPK	Glycosyl transferase (Group 1
THII_2301	ENOG4105CKK	Glycosyl transferase, family 2
THII_2303	ENOG4105CAQ	asparagine synthetase
THII_2305	ENOG4105C3G	gtp-binding protein
THII_2306	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
THII_2307	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
THII_2308	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
THII_2309	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
THII_2310	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
THII_2311	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
THII_2312	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THII_2313	ENOG4108IAB	Phoh family
THII_2314	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
THII_2316	ENOG4108NGH	radical SAM domain protein
THII_2326	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
THII_2327	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
THII_2331	ENOG4108ZP8	Acetolactate synthase small subunit
THII_2332	ENOG4105C7K	acetolactate synthase
THII_2338	ENOG4105DAP	Nicotinate phosphoribosyltransferase
THII_2339	ENOG41082J7	Rhodanese domain protein
THII_2340	ENOG4105VCQ	rubredoxin
THII_2341	ENOG4107ZCS	Phosphomethylpyrimidine kinase
THII_2342	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
THII_2343	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
THII_2348	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
THII_2349	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
THII_2352	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
THII_2353	ENOG4105F8J	Adenylate Guanylate cyclase
THII_2358	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THII_2359	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
THII_2360	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
THII_2361	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
THII_2365	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THII_2366	ENOG4105EHM	Aminoglycoside phosphotransferase
THII_2367	ENOG4108S0S	Nucleotidyl transferase
THII_2368	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
THII_2369	ENOG41082NX	50s ribosomal protein l35
THII_2370	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
THII_2371	ENOG4105C22	threonyL-tRNA synthetase
THII_2375	ENOG4105BZU	Histidine kinase
THII_2378	ENOG4105IJJ	transcriptional regulator, crp fnr family
THII_2390	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
THII_2391	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
THII_2392	ENOG4107QJR	hflk protein
THII_2393	ENOG4105EPW	hflc protein
THII_2395	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
THII_2396	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
THII_2397	ENOG4105C2I	pirin domain protein
THII_2406	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
THII_2407	ENOG4105F3H	Histidine kinase
THII_2413	ENOG4105DZB	Electron transport complex
THII_2415	ENOG4105CSM	endonuclease III
THII_2416	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
THII_2425	ENOG4105C01	Dihydroxy-acid dehydratase
THII_2428	ENOG4105C79	DNA protecting protein DprA
THII_2429	ENOG4108RPN	Protein smg homolog
THII_2431	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
THII_2432	ENOG4108YZA	Nitrogen regulatory protein pii
THII_2433	ENOG4105BZU	Histidine kinase
THII_2435	ENOG4107QKZ	Ompa motb domain protein
THII_2439	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
THII_2440	ENOG4105BZU	Histidine kinase
THII_2442	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
THII_2443	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
THII_2444	ENOG4105BZU	Histidine kinase
THII_2446	ENOG4105C8Q	Methyl-accepting chemotaxis
THII_2447	ENOG4105C8Q	Methyl-accepting chemotaxis
THII_2449	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
THII_2450	ENOG4107QR9	Iron-sulfur cluster binding protein
THII_2459	ENOG4105E3S	small subunit
THII_2462	ENOG4105E3S	small subunit
THII_2464	ENOG4105CY3	ABC transporter, permease
THII_2465	ENOG41069ER	domain protein
THII_2475	ENOG4105D3Q	Sugar transferase
THII_2478	ENOG4105EE5	Membrane protein terC
THII_2485	ENOG4108MBK	is1 orf2
THII_2488	ENOG4105UBK	short-chain dehydrogenase reductase
THII_2489	ENOG4108IYU	L-aspartate oxidase
THII_2491	ENOG4105C0H	protease
THII_2493	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
THII_2494	ENOG4105C3F	Signal peptidase i
THII_2497	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
THII_2503	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
THII_2508	ENOG41086B8	CoB-CoM heterodisulfide reductase
THII_2514	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
THII_2520	ENOG4107QHF	type ii secretion system protein e
THII_2522	ENOG4105VDB	UPF0125 protein
THII_2523	ENOG4108E8M	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
THII_2527	ENOG4108UT2	hemolysin iii
THII_2528	ENOG4105BZU	Histidine kinase
THII_2529	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
THII_2531	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
THII_2532	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
THII_2533	ENOG4105DFU	Cell wall formation (By similarity)
THII_2534	ENOG4105D4A	Cell wall formation (By similarity)
THII_2535	ENOG4105CPF	Cell wall formation (By similarity)
THII_2537	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
THII_2538	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
THII_2539	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
THII_2541	ENOG4105DR5	peptidase
THII_2545	ENOG4105D7W	serine acetyltransferase
THII_2546	ENOG4105CDV	Ompa motb domain protein
THII_2548	ENOG4105GNX	MltA-interacting MipA family protein
THII_2552	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
THII_2554	ENOG4105DCC	Formylmethanofuran dehydrogenase subunit A
THII_2555	ENOG4105DS4	PAS PAC sensor Signal transduction histidine kinase
THII_2556	ENOG4108JUA	Transcriptional regulator
THII_2564	ENOG4105VDB	UPF0125 protein
THII_2565	ENOG4108E8M	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
THII_2567	ENOG4105D6A	Electron transport complex
THII_2568	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
THII_2569	ENOG4108R3D	Electron transport complex
THII_2570	ENOG4105DGN	Electron transport complex
THII_2571	ENOG4105DS4	PAS PAC sensor Signal transduction histidine kinase
THII_2572	ENOG4108JUA	Transcriptional regulator
THII_2578	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
THII_2580	ENOG4105ES5	Histidine kinase
THII_2581	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THII_2582	ENOG4105BZU	Histidine kinase
THII_2584	ENOG4108V1T	peptidylprolyl cis-trans isomerase
THII_2588	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
THII_2589	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
THII_2594	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
THII_2595	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
THII_2596	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
THII_2597	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
THII_2598	ENOG4107YZP	Rhodanese domain protein
THII_2602	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
THII_2603	ENOG4108I5D	sulfate abc transporter
THII_2604	ENOG4105ECW	sulfate abc transporter
THII_2605	ENOG4108IJ6	ABC transporter
THII_2610	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
THII_2611	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
THII_2622	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
THII_2628	ENOG4105WVQ	Fe-S assembly protein IscX
THII_2629	ENOG4108ZIT	Ferredoxin, 2FE-2S
THII_2631	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
THII_2632	ENOG4108Z4V	iron-sulfur cluster assembly
THII_2635	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
THII_2640	ENOG4107T8Q	Glycosyl transferase (Group 1
THII_2641	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
THII_2646	ENOG4108IQE	Amp-dependent synthetase and ligase
THII_2647	ENOG41068JE	domain protein
THII_2648	ENOG41068JE	domain protein
THII_2650	ENOG4105CGH	5'-nucleotidase
THII_2651	ENOG4105PGM	cation diffusion facilitator family transporter
THII_2652	ENOG4105DQR	SNARE associated Golgi
THII_2658	ENOG41083P1	competence protein ComEA helix-hairpin-helix repeat protein
THII_2662	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
THII_2663	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
THII_2664	ENOG4105EV9	Alpha Beta Hydrolase
THII_2670	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
THII_2675	ENOG4105XPQ	lipid carrier protein
THII_2676	ENOG4106RZ4	Peptidase U32
THII_2677	ENOG4105CFP	Peptidase U32
THII_2678	ENOG4105N5T	Radical SAM Protein
THII_2688	ENOG4105NAE	bifunctional deaminase-reductase domain protein
THII_2689	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
THII_2691	ENOG4107UWY	Methyltransferase
THII_2692	ENOG4105DEF	Extracellular solute-binding protein, family 5
THII_2693	ENOG4105BZU	Histidine kinase
THII_2694	ENOG4105C45	hydrogenase expression formation protein (HypE)
THII_2696	ENOG4108MN8	Membrane
THII_2697	ENOG4105C5H	ABC transporter
THII_2699	ENOG4108UNF	response regulator
THII_2700	ENOG4108VAU	general secretion pathway protein G
THII_2707	ENOG4107QJE	Chromosome Partitioning Protein
THII_2709	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
THII_2710	ENOG4105CFG	Acts as a chaperone (By similarity)
THII_2711	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
THII_2712	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
THII_2713	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
THII_2714	ENOG41075W9	High frequency lysogenization protein HflD homolog
THII_2718	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
THII_2721	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
THII_2724	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
THII_2725	ENOG4105PM1	preprotein translocase subunit SecE
THII_2726	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
THII_2727	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
THII_2728	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
THII_2729	ENOG4108VZM	50s ribosomal protein L10
THII_2730	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
THII_2731	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
THII_2732	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
THII_2735	ENOG4105CJ1	ABC, transporter
THII_2736	ENOG4107QWP	ABC-2 type transporter
THII_2738	ENOG4107XPZ	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
THII_2747	ENOG4108JA2	transcriptioN-repair coupling factor
THII_2748	ENOG4108HMW	glycyl-tRNA synthetase, alpha subunit
THII_2749	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
THII_2751	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
THII_2752	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THII_2753	ENOG4107TUY	Histidine kinase
THII_2755	ENOG4107YIM	Involved in the transcription termination process (By similarity)
THII_2756	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
THII_2757	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
THII_2760	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
THII_2761	ENOG4105W8H	transhydrogenase (subunit alpha
THII_2762	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
THII_2763	ENOG4105VEQ	Cold shock protein
THII_2764	ENOG4105CQB	FAD linked oxidase domain protein
THII_2771	ENOG4105IBP	Cyclic peptide transporter
THII_2776	ENOG4105C4X	radical SAM domain protein
THII_2780	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
THII_2781	ENOG4105ENH	Sulfatase
THII_2782	ENOG4107P5I	polyketide synthase
THII_2794	ENOG41086VD	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
THII_2795	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
THII_2796	ENOG4105CEY	Amp-dependent synthetase and ligase
THII_2800	ENOG4105CSA	Coproporphyrinogen iii oxidase
THII_2803	ENOG4105CJ0	Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate (By similarity)
THII_2805	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
THII_2806	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
THII_2810	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
THII_2811	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
THII_2812	ENOG4108Z1B	Cyclase dehydrase
THII_2813	ENOG4105VDB	UPF0125 protein
THII_2814	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
THII_2815	ENOG41090R7	Ferric uptake
THII_2825	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
THII_2826	ENOG4105D1A	Methyltransferase
THII_2827	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
THII_2828	ENOG4107QMP	dna polymerase iii subunits gamma and tau
THII_2836	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
THII_2838	ENOG4108NEV	two component transcriptional regulator, LytTR family
THII_2840	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
THII_2841	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
THII_2843	ENOG4108VAU	general secretion pathway protein G
THII_2844	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
THII_2848	ENOG4105DUM	transcriptional regulator, lysR family
THII_2851	ENOG4105YB8	TM2 domain containing protein
THII_2875	ENOG4105F64	nitrite reductase
THII_2877	ENOG4106P6N	cytochrome d1 heme region
THII_2878	ENOG4108ZGY	Transcriptional regulator (AsnC family)
THII_2880	ENOG4108ZGY	Transcriptional regulator (AsnC family)
THII_2881	ENOG4108UMR	transcriptional regulator AsnC family
THII_2885	ENOG4106RE7	Cytochrome
THII_2889	ENOG4108BGM	Quinol dehydrogenase periplasmic component
THII_2891	ENOG4108WUZ	(ABC) transporter
THII_2907	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
THII_2910	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
THII_2911	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
THII_2912	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
THII_2913	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
THII_2914	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
THII_2916	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
THII_2917	ENOG4105K46	50S ribosomal protein l27
THII_2918	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
THII_2922	ENOG4105FA0	parb-like partition protein
THII_2931	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
THII_2932	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
THII_2933	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
THII_2935	ENOG4108R6K	riboflavin synthase, subunit alpha
THII_2936	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
THII_2937	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
THII_2938	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
THII_2939	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
THII_2940	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
THII_2942	ENOG4108NJZ	Sensory box GGDEF EAL domain protein
THII_2945	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THII_2946	ENOG4105C8S	subunit m
THII_2947	ENOG4105D65	subunit l
THII_2948	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THII_2949	ENOG4105DF2	NADH dehydrogenase subunit j
THII_2952	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
THII_2953	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
THII_2954	ENOG4108IEH	NADH dehydrogenase subunit g
THII_2959	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
THII_2960	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
THII_2963	ENOG4105BZU	Histidine kinase
THII_2964	ENOG4105WAP	TPR repeat-containing protein
THII_2966	ENOG4105CGK	Exodeoxyribonuclease III
THII_2969	ENOG4105BZU	Histidine kinase
THII_2971	ENOG4105C8N	cysteinyl-tRNA synthetase
THII_2972	ENOG4105BZU	Histidine kinase
THII_2975	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THII_2976	ENOG4105BZU	Histidine kinase
THII_2977	ENOG4107QHF	type ii secretion system protein e
THII_2980	ENOG4105DFA	alanine racemase domain protein
THII_2981	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THII_2982	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
THII_2986	ENOG4108RS6	transposase
THII_2987	ENOG4106R49	Methyltransferase
THII_3000	ENOG4105C75	arginyL-tRNA synthetase
THII_3001	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
THII_3008	ENOG4105C0B	DNA polymerase III (alpha subunit)
THII_3016	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
THII_3018	ENOG4105IQ5	FAD linked oxidase domain protein
THII_3019	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
THII_3021	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
THII_3022	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
THII_3027	ENOG4105F4R	Transcriptional regulator mode
THII_3028	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
THII_3031	ENOG4105FAE	von Willebrand factor, type A
THII_3033	ENOG4105BZU	Histidine kinase
THII_3034	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
THII_3036	ENOG4105D9P	serine threonine protein kinase
THII_3037	ENOG4108ZF3	Phosphatase
THII_3038	ENOG4108ZF3	Phosphatase
THII_3039	ENOG4107Y7W	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
THII_3043	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THII_3044	ENOG4105TNG	K13735 adhesin invasin
THII_3049	ENOG4105DJF	DNA polymerase III, delta' subunit
THII_3051	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
THII_3057	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
THII_3059	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
THII_3062	ENOG4105DHQ	Histidine kinase
THII_3063	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
THII_3068	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
THII_3070	ENOG4105FAE	von Willebrand factor, type A
THII_3072	ENOG4105DSY	exodeoxyribonuclease V, gamma
THII_3074	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
THII_3075	ENOG4105C5H	ABC transporter
THII_3080	ENOG4105C4K	Nad synthetase
THII_3081	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
THII_3085	ENOG4105XV5	nifz family
THII_3086	ENOG410605C	May protect the nitrogenase Fe-Mo protein from oxidative damage (By similarity)
THII_3088	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
THII_3092	ENOG4105C7Z	Conserved Protein
THII_3093	ENOG4105SYT	Methylenetetrahydrofolate reductase
THII_3094	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THII_3096	ENOG4105GVR	general secretion pathway protein D
THII_3097	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
THII_3098	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
THII_3099	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
THII_3102	ENOG4108JU6	CBS domain protein
THII_3107	ENOG4105DR5	peptidase
THII_3113	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
THII_3114	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
THII_3121	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
THII_3123	ENOG4108KMV	Glycosyl transferase (Group 1
THII_3125	ENOG4105PS4	nifq family
THII_3126	ENOG4105U82	Ferredoxin
THII_3127	ENOG4105KXW	Ferredoxin
THII_3128	ENOG4105CNW	domain protein
THII_3129	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
THII_3130	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
THII_3133	ENOG4107QZF	nitrite reductase NADPH large subunit
THII_3134	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
THII_3136	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
THII_3138	ENOG4108FN7	Aldo keto reductase
THII_3139	ENOG4108HMN	Caspase domain
THII_3140	ENOG4108HMN	Caspase domain
THII_3145	ENOG4105BZU	Histidine kinase
THII_3147	ENOG41080ET	plasmid maintenance system killer protein
THII_3148	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
THII_3151	ENOG4105ESV	Glycosyl transferase, family 4
THII_3153	ENOG4108K0D	peptidase, M48
THII_3156	ENOG4105FE1	phytoene synthase
THII_3161	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
THII_3162	ENOG4105C8V	SAICAR synthetase
THII_3165	ENOG4105DA4	cytochrome c-type biogenesis protein
THII_3166	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
THII_3167	ENOG4105X3C	heme exporter protein
THII_3168	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
THII_3169	ENOG4105C8Q	Methyl-accepting chemotaxis
THII_3173	ENOG4105DHJ	ABC, transporter
THII_3176	ENOG4105J5G	Transferase hexapeptide repeat containing protein
THII_3177	ENOG4107QZM	n-acetylglutamate synthase
THII_3180	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
THII_3185	ENOG4105CFP	Peptidase U32
THII_3186	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
THII_3192	ENOG4107QRI	Phosphoketolase
THII_3198	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
THII_3200	ENOG4105D6A	Electron transport complex
THII_3206	ENOG4107S75	HAD-superfamily hydrolase subfamily IA variant 3
THII_3208	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
THII_3210	ENOG4105C8Q	Methyl-accepting chemotaxis
THII_3222	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
THII_3223	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
THII_3224	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
THII_3228	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
THII_3232	ENOG4108DG9	Smr protein MutS2
THII_3233	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
THII_3240	ENOG4105E2V	Glycosyltransferase 36
THII_3247	ENOG4105VDW	Csbd family
THII_3251	ENOG4105KWW	Biogenesis protein
THII_3252	ENOG4108M1T	Cytochrome c-type biogenesis protein
THII_3258	ENOG4107QN2	dihydrolipoyl dehydrogenase
THII_3261	ENOG4107QY8	reductase
THII_3262	ENOG4105QAX	Iron-sulfur
THII_3278	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
THII_3279	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
THII_3280	ENOG4107QMS	site-determining protein
THII_3281	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
THII_3285	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
THII_3286	ENOG4105DWV	Homoserine O-trans-acetylase
THII_3287	ENOG4105DWV	Homoserine O-trans-acetylase
THII_3288	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
THII_3289	ENOG4105CS6	Rhs element vgr protein
THII_3300	ENOG4105D7Q	type ii secretion system
THII_3303	ENOG4105D3R	alkyl hydroperoxide reductase
THII_3307	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
THII_3308	ENOG4108Z1Z	gCN5-related N-acetyltransferase
THII_3310	ENOG4105DUM	transcriptional regulator, lysR family
THII_3311	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
THII_3315	ENOG4105DPX	Hydrogenase, large subunit
THII_3316	ENOG4106T9E	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
THII_3320	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
THII_3321	ENOG4105C8U	phosphate abc transporter
THII_3322	ENOG4105C8U	phosphate abc transporter
THII_3323	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
THII_3325	ENOG4108YY7	Invasion gene expression up-regulator SirB
THII_3338	ENOG4105D2N	Aldolase
THII_3339	ENOG4105CA9	Pyruvate kinase
THII_3340	ENOG4105BZA	Phosphoglycerate kinase
THII_3341	ENOG4105W0E	50S ribosomal protein L33
THII_3343	ENOG4105C3R	Methionine synthase
THII_3345	ENOG4105BZU	Histidine kinase
THII_3347	ENOG4105EYW	Ion transport protein
THII_3350	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
THII_3351	ENOG41067HS	methyltransferase
THII_3361	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
THII_3362	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
THII_3363	ENOG4108Z6B	deaminase
THII_3364	ENOG4105CUT	histidyl-tRNA synthetase
THII_3365	ENOG4105N21	Membrane
THII_3366	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
THII_3371	ENOG4107STQ	Multicopper oxidase
THII_3379	ENOG4108WFR	AraC Family Transcriptional Regulator
THII_3386	ENOG4105CIH	Imidazole acetol-phosphate transaminase
THII_3389	ENOG4107Y2X	deaminase
THII_3391	ENOG4105E1F	short-chain dehydrogenase reductase
THII_3395	ENOG4105D7Q	type ii secretion system
THII_3396	ENOG4105CHM	Aminotransferase
THII_3397	ENOG4105D6E	homoserine dehydrogenase
THII_3398	ENOG4105VWV	general secretion pathway protein h
THII_3401	ENOG4107EJC	Preprotein translocase subunit SecG
THII_3402	ENOG4105CP7	Triose-phosphate isomerase
THII_3405	ENOG4107VXZ	Hydrolase
THII_3410	ENOG4108YXA	Membrane
THII_3411	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
THII_3412	ENOG4105DSJ	YicC domain protein
THII_3413	ENOG4105BZU	Histidine kinase
THII_3415	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THII_3420	ENOG4105IDI	abc transporter atp-binding protein
THII_3421	ENOG4105D49	3-dehydroquinate synthase
THII_3422	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
THII_3428	ENOG4105C03	ribonuclease
THII_3429	ENOG4105EI2	Pseudouridine synthase
THII_3430	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
THII_3431	ENOG4108E8C	) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
THII_3433	ENOG4105WMR	Protein CrcB homolog
THII_3434	ENOG4105KJJ	Uncharacterized ACR, COG1993
THII_3435	ENOG4105WMR	Protein CrcB homolog
THII_3436	ENOG4105KJJ	Uncharacterized ACR, COG1993
THII_3437	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
THII_3444	ENOG4105C7S	Dehydrogenase
THII_3445	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
THII_3446	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
THII_3447	ENOG4105BZU	Histidine kinase
THII_3448	ENOG4105BZU	Histidine kinase
THII_3449	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
THII_3455	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
THII_3456	ENOG4105CDU	Replicative dna helicase
THII_3457	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
THII_3458	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
THII_3459	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
THII_3461	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
THII_3462	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
THII_3463	ENOG4105C31	Tryptophanyl-tRNA synthetase
THII_3464	ENOG4108Z4T	Peptidase M50
THII_3465	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
THII_3466	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
THII_3467	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THII_3468	ENOG4105BZU	Histidine kinase
THII_3469	ENOG4105BZU	Histidine kinase
THII_3470	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
THII_3473	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
THII_3480	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
THII_3482	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
THII_3484	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
THII_3485	ENOG4108JQB	penicillin-binding protein 1C
THII_3487	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
THII_3489	ENOG4105DKP	glycosyl transferase, family 9
THII_3491	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
THII_3498	ENOG4107QSN	dihydrolipoamide acetyltransferase
THII_3499	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
THII_3509	ENOG4108Z43	UPF0250 protein
THII_3510	ENOG4105F0I	Aminotransferase
THII_3511	ENOG4105DZ1	carboxypeptidase
THII_3512	ENOG4105K6T	rare lipoprotein A
THII_3513	ENOG4105CVE	Lytic murein transglycosylase
THII_3514	ENOG4105CNI	cell division protein FtsW
THII_3515	ENOG4105CJN	penicillin-binding protein
THII_3516	ENOG4105VQ7	Rod shape-determining protein MreD
THII_3517	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
THII_3518	ENOG4105DFF	Rod shape-determining protein mreb
THII_3520	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
THII_3521	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
THII_3527	ENOG4105DHP	deoxycytidine triphosphate deaminase
THII_3528	ENOG4105D1F	ATP-binding protein
THII_3529	ENOG4105W87	Cbs domain
THII_3530	ENOG4105CVR	type I restriction-modification system
THII_3532	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
THII_3537	ENOG4105CGZ	zinc metallopeptidase
THII_3541	ENOG4107QTF	adenylosuccinate lyase
THII_3542	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
THII_3544	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
THII_3546	ENOG4105C0H	protease
THII_3547	ENOG4105EAH	synthase
THII_3549	ENOG4108YGX	
THII_3552	ENOG4105CE1	Ferrous iron transport protein b
THII_3562	ENOG4107SDT	Homocitrate synthase
THII_3566	ENOG4105E3A	(ABC) transporter
THII_3567	ENOG4105DA5	(ABC) transporter
THII_3570	ENOG4107PE3	Mammalian cell entry related domain protein
THII_3571	ENOG4107SM8	Adenylate Guanylate cyclase
THII_3575	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
THII_3577	ENOG4105CAQ	asparagine synthetase
THII_3580	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
THII_3582	ENOG4105HHA	aminodeoxychorismate lyase
THII_3583	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
THII_3584	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
THII_3585	ENOG4105CHR	reductase
THII_3586	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
THII_3587	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
THII_3588	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
THII_3589	ENOG4105VGS	50s ribosomal protein l32
THII_3590	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
THII_3591	ENOG4108UHJ	MAF-like protein
THII_3592	ENOG4108USZ	hydrogenase
THII_3595	ENOG4105C59	p-type ATPase
THII_3596	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
THII_3597	ENOG4105C4R	Atp-dependent dna helicase
THII_3598	ENOG4105CUB	amino acid
THII_3603	ENOG4105CS6	Rhs element vgr protein
THII_3610	ENOG4105EEI	dihydropteroate synthase
THII_3612	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
THII_3613	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
THII_3614	ENOG4105BZU	Histidine kinase
THII_3615	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
THII_3616	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
THII_3617	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
THII_3622	ENOG4105F8J	Adenylate Guanylate cyclase
THII_3623	ENOG4105DK0	Indole-3-glycerol phosphate synthase
THII_3624	ENOG4108I0Q	anthranilate phosphoribosyltransferase
THII_3628	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
THII_3629	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
THII_3630	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
THII_3631	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
THII_3633	ENOG4107R7Y	intracellular protease Pfpi family
THII_3634	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
THII_3639	ENOG4105DJ9	glucan biosynthesis protein
THII_3641	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
THII_3642	ENOG4107VAM	peptidase, m28
THII_3648	ENOG4105BZU	Histidine kinase
THII_3656	ENOG4107YZX	Universal stress protein
THII_3658	ENOG4105D0M	Protease HtpX homolog
THII_3660	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
THII_3661	ENOG4105K8N	protein family UPF0079, ATPase
THII_3665	ENOG4105E4C	Lytic transglycosylase catalytic
THII_3675	ENOG4105CQS	hydrogenase expression formation protein HypD
THII_3677	ENOG4106F5Q	Membrane
THII_3682	ENOG4105BZU	Histidine kinase
THII_3690	ENOG4105BZ8	glutamate synthase
THII_3692	ENOG4105DDK	oxidoreductase, beta subunit
THII_3693	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
THII_3700	ENOG4105CRQ	synthase (Component I)
THII_3701	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
THII_3702	ENOG4105DJV	ribulose-phosphate 3-epimerase
THII_3705	ENOG4106032	Glutathionylspermidine synthase
THII_3706	ENOG4105VFU	Rna-binding protein
THII_3708	ENOG4105CSA	Coproporphyrinogen iii oxidase
THII_3712	ENOG4105C9X	ppx gppa phosphatase
THII_3715	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
THII_3716	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
THII_3722	ENOG4105BZU	Histidine kinase
THII_3724	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
THII_3725	ENOG4105BZM	domain protein
THII_3733	ENOG41080ET	plasmid maintenance system killer protein
THII_3734	ENOG4105BZU	Histidine kinase
THII_3736	ENOG4105CVJ	phosphoglycerate mutase
THII_3737	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
THII_3739	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
THII_3740	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
THII_3743	ENOG41076E6	Uroporphyrinogen-III Synthase
THII_3744	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
THII_3761	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
THII_3765	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
THII_3766	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
THII_3767	ENOG4108RG0	uracil-dna glycosylase
THII_3768	ENOG4105BZU	Histidine kinase
THII_3773	ENOG4105CIN	aminoacyl-histidine dipeptidase
THII_3778	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
THII_3779	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
THII_3780	ENOG41063SB	peptidase
THII_3781	ENOG4105CN1	protease
THII_3782	ENOG4107S0N	DJ-1 family
THII_3783	ENOG4105BZN	citrate synthase
THII_3784	ENOG4106BE1	Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers (By similarity)
THII_3790	ENOG4105D9P	serine threonine protein kinase
THII_3792	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THII_3799	ENOG4105C10	Electron transfer flavoprotein
THII_3800	ENOG4105BZJ	Electron transfer flavoprotein
THII_3801	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
THII_3802	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
THII_3807	ENOG41090A4	Pterin carbinolamine dehydratase
THII_3809	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
THII_3810	ENOG41090EK	ompa motb domain protein
THII_3816	ENOG4107QN1	sodium solute
THII_3817	ENOG41062QD	Membrane
THII_3822	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
THII_3827	ENOG4105VF7	tolerance protein
THII_3828	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
THII_3829	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
THII_3833	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THII_3834	ENOG4105BZU	Histidine kinase
THII_3835	ENOG4105BZU	Histidine kinase
THII_3836	ENOG41090A1	ferritin
THII_3837	ENOG4105VUC	UPF0237 protein
THII_3838	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
THII_3850	ENOG4108UJD	30S ribosomal protein S9
THII_3857	ENOG4108KXV	response regulator
THII_3858	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
THII_3860	ENOG4105E33	succinate dehydrogenase
THII_3861	ENOG4105E4C	Lytic transglycosylase catalytic
THII_3864	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
THII_3866	ENOG4105CEN	a g-specific adenine glycosylase
THII_3867	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
THII_3869	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
THII_3870	ENOG4105C03	ribonuclease
THII_3872	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
THII_3873	ENOG4105DK7	lysyl-tRNA synthetase
THII_3879	ENOG4105K5M	30s ribosomal protein S16
THII_3880	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
THII_3881	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
THII_3882	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
THII_3883	ENOG4105T95	Thiol disulfide interChange protein
THII_3889	ENOG4105BZU	Histidine kinase
THII_3891	ENOG4107QX8	SPFH domain, Band 7 family protein
THII_3892	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
THII_3895	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
THII_3896	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
THII_3897	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
THII_3898	ENOG4108UKZ	OsmC family
THII_3899	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
THII_3900	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
THII_3902	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
THII_3904	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
THII_3905	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
THII_3906	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
THII_3910	ENOG4108JQ5	ABC transporter
THII_3911	ENOG4105BZU	Histidine kinase
THII_3912	ENOG4105D1S	lipid A biosynthesis
THII_3913	ENOG4105UYK	outer membrane protein a
THII_3915	ENOG4105D9N	nucleoside
THII_3926	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
THII_3927	ENOG4108JQC	penicillin-binding protein 1A
THII_3933	ENOG4105E4G	Type IV pilus
THII_3937	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
THII_3938	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
THII_3941	ENOG4105CDH	Citrulline--aspartate ligase
THII_3944	ENOG4105BZS	acriflavin resistance protein
THII_3945	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
THII_3946	ENOG4105C8Q	Methyl-accepting chemotaxis
THII_3947	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
THII_3950	ENOG41087YS	Phage shock protein A