locus-tag	class	description
HMY34_00015	COG0714	Associated with various cellular activities
HMY34_00025	COG1410	methionine synthase
HMY34_00025	COG0646	methionine synthase
HMY34_00040	COG1850	ribulose-bisphosphate carboxylase activity
HMY34_00070	COG0393	Putative heavy-metal-binding
HMY34_00075	COG0277	FAD linked oxidase domain protein
HMY34_00085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMY34_00090	COG0745	RESPONSE REGULATOR receiver
HMY34_00155	COG0303	'Molybdopterin
HMY34_00180	COG2824	Alkylphosphonate utilization operon protein PhnA
HMY34_00185	COG2860	membrane
HMY34_00190	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HMY34_00205	COG0415	Belongs to the DNA photolyase family
HMY34_00210	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HMY34_00220	COG0754	glutathionylspermidine amidase activity
HMY34_00245	COG0628	permease
HMY34_00250	COG3459	Glycosyltransferase 36 associated
HMY34_00260	COG3237	CsbD-like
HMY34_00290	COG1136	(ABC) transporter
HMY34_00310	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HMY34_00325	COG0789	Transcriptional regulator
HMY34_00345	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HMY34_00350	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HMY34_00370	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HMY34_00370	COG0515	serine threonine protein kinase
HMY34_00390	COG0515	serine threonine protein kinase
HMY34_00390	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HMY34_00410	COG0519	Catalyzes the synthesis of GMP from XMP
HMY34_00410	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HMY34_00425	COG1570	exodeoxyribonuclease VII activity
HMY34_00445	COG1509	lysine 2,3-aminomutase activity
HMY34_00460	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HMY34_00465	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HMY34_00470	COG1862	Preprotein translocase
HMY34_00475	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HMY34_00480	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HMY34_00485	COG3012	SEC-C Motif Domain Protein
HMY34_00490	COG2226	methyltransferase
HMY34_00495	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HMY34_00500	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HMY34_00515	COG0525	valine-tRNA ligase activity
HMY34_00540	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HMY34_00545	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HMY34_00550	COG1674	ftsk spoiiie
HMY34_00555	COG0492	ferredoxin-NADP+ reductase activity
HMY34_00560	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HMY34_00565	COG3132	Protein of unknown function, DUF480
HMY34_00575	COG0308	aminopeptidase N
HMY34_00595	COG2226	methyltransferase
HMY34_00640	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HMY34_00650	COG3852	Histidine kinase
HMY34_00680	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HMY34_00685	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HMY34_00795	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HMY34_00815	COG3008	intermembrane lipid transfer
HMY34_00820	COG2995	paraquat-inducible protein a
HMY34_00825	COG2995	paraquat-inducible protein a
HMY34_00855	COG0583	DNA-binding transcription factor activity
HMY34_00895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMY34_00910	COG1358	cellular component organization or biogenesis
HMY34_00925	COG1414	Transcriptional regulator
HMY34_00940	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HMY34_00970	COG2951	lytic endotransglycosylase activity
HMY34_01005	COG4804	nuclease activity
HMY34_01015	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HMY34_01030	COG1320	monovalent cation:proton antiporter activity
HMY34_01035	COG2212	antiporter activity
HMY34_01040	COG1863	multisubunit Na H antiporter MnhE subunit
HMY34_01045	COG0651	ATP synthesis coupled electron transport
HMY34_01050	COG1006	Multisubunit Na H antiporter MnhC subunit
HMY34_01055	COG2111	Na H antiporter
HMY34_01055	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HMY34_01065	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HMY34_01070	COG0567	Dehydrogenase, E1 component
HMY34_01080	COG2009	succinate dehydrogenase
HMY34_01090	COG1053	succinate dehydrogenase
HMY34_01100	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HMY34_01115	COG2885	chlorophyll binding
HMY34_01120	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HMY34_01120	COG3743	rRNA binding
HMY34_01135	COG0322	excinuclease ABC activity
HMY34_01140	COG1404	Belongs to the peptidase S8 family
HMY34_01150	COG1070	Carbohydrate kinase
HMY34_01155	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HMY34_01160	COG0857	belongs to the CobB CobQ family
HMY34_01160	COG0280	phosphate acetyltransferase
HMY34_01185	COG0215	cysteine-tRNA ligase activity
HMY34_01210	COG0459	protein refolding
HMY34_01215	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HMY34_01225	COG5002	protein histidine kinase activity
HMY34_01225	COG5001	Diguanylate cyclase
HMY34_01235	COG4232	protein-disulfide reductase activity
HMY34_01250	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMY34_01255	COG0628	permease
HMY34_01265	COG2885	chlorophyll binding
HMY34_01270	COG0564	pseudouridine synthase activity
HMY34_01280	COG0557	exoribonuclease II activity
HMY34_01285	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HMY34_01300	COG1322	Protein conserved in bacteria
HMY34_01315	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HMY34_01320	COG2894	cell division
HMY34_01325	COG0850	regulation of cytokinetic process
HMY34_01335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMY34_01345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HMY34_01345	COG0519	Catalyzes the synthesis of GMP from XMP
HMY34_01350	COG2258	MOSC domain
HMY34_01370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HMY34_01380	COG0531	amino acid
HMY34_01385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HMY34_01390	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HMY34_01405	COG1266	CAAX protease self-immunity
HMY34_01500	COG2944	sequence-specific DNA binding
HMY34_01510	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HMY34_01530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HMY34_01540	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HMY34_01545	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HMY34_01550	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HMY34_01615	COG1215	transferase activity, transferring glycosyl groups
HMY34_01625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HMY34_01655	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HMY34_01665	COG0028	Belongs to the TPP enzyme family
HMY34_01680	COG3040	lipid binding
HMY34_01685	COG3384	dioxygenase
HMY34_01715	COG3046	protein related to deoxyribodipyrimidine photolyase
HMY34_01725	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HMY34_01730	COG0277	FAD linked oxidase domain protein
HMY34_01735	COG0277	FAD linked oxidase domain protein
HMY34_01740	COG0247	lactate metabolic process
HMY34_01750	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HMY34_01760	COG0148	phosphopyruvate hydratase activity
HMY34_01765	COG2877	3-deoxy-8-phosphooctulonate synthase activity
HMY34_01770	COG0504	CTP synthase activity
HMY34_01790	COG3264	Mechanosensitive ion channel
HMY34_01790	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
HMY34_01810	COG0776	regulation of translation
HMY34_01815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMY34_01815	COG0072	phenylalanine-tRNA ligase activity
HMY34_01820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HMY34_01825	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HMY34_01830	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HMY34_01840	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HMY34_01850	COG0326	Molecular chaperone. Has ATPase activity
HMY34_01870	COG1366	Belongs to the anti-sigma-factor antagonist family
HMY34_01870	COG2202	Pas domain
HMY34_01885	COG4591	ABC-type transport system involved in lipoprotein release permease component
HMY34_01890	COG4591	ABC-type transport system involved in lipoprotein release permease component
HMY34_01895	COG1136	(ABC) transporter
HMY34_01915	COG0138	bifunctional purine biosynthesis protein purh
HMY34_01920	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HMY34_01990	COG0582	viral genome integration into host DNA
HMY34_02025	COG2814	Major facilitator Superfamily
HMY34_02065	COG1294	oxidase, subunit
HMY34_02070	COG4890	Cyd operon protein YbgT
HMY34_02080	COG0523	cobalamin synthesis protein
HMY34_02085	COG0803	Belongs to the bacterial solute-binding protein 9 family
HMY34_02095	COG1121	(ABC) transporter
HMY34_02105	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HMY34_02115	COG0523	cobalamin synthesis protein
HMY34_02120	COG0735	belongs to the Fur family
HMY34_02150	COG1858	cytochrome C peroxidase
HMY34_02170	COG0513	Belongs to the DEAD box helicase family
HMY34_02180	COG0513	Belongs to the DEAD box helicase family
HMY34_02185	COG2814	Major facilitator Superfamily
HMY34_02190	COG0629	single-stranded DNA binding
HMY34_02200	COG2003	Belongs to the UPF0758 family
HMY34_02205	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HMY34_02210	COG0756	dUTP diphosphatase activity
HMY34_02225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HMY34_02250	COG1472	Belongs to the glycosyl hydrolase 3 family
HMY34_02260	COG4166	transmembrane transport
HMY34_02265	COG3243	poly(R)-hydroxyalkanoic acid synthase
HMY34_02290	COG0559	Belongs to the binding-protein-dependent transport system permease family
HMY34_02295	COG0683	leucine binding
HMY34_02300	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HMY34_02315	COG0372	Belongs to the citrate synthase family
HMY34_02340	COG1185	polyribonucleotide nucleotidyltransferase activity
HMY34_02360	COG2391	methyltransferase activity
HMY34_02370	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HMY34_02375	COG0484	heat shock protein binding
HMY34_02380	COG0443	Heat shock 70 kDa protein
HMY34_02385	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HMY34_02390	COG3118	belongs to the thioredoxin family
HMY34_02395	COG5339	Protein conserved in bacteria
HMY34_02410	COG0444	Belongs to the ABC transporter superfamily
HMY34_02425	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HMY34_02425	COG4797	methyltransferase
HMY34_02435	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HMY34_02445	COG0105	UTP biosynthetic process
HMY34_02450	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HMY34_02465	COG0124	histidyl-tRNA synthetase
HMY34_02470	COG2976	Protein conserved in bacteria
HMY34_02475	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HMY34_02485	COG1454	alcohol dehydrogenase
HMY34_02515	COG4456	Virulence-associated protein
HMY34_02525	COG0037	tRNA processing
HMY34_02530	COG0825	malonyl-CoA metabolic process
HMY34_02535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HMY34_02540	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
HMY34_02550	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
HMY34_02560	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HMY34_02565	COG2137	regulation of response to DNA damage stimulus
HMY34_02585	COG3243	poly(R)-hydroxyalkanoic acid synthase
HMY34_02590	COG1546	Belongs to the CinA family
HMY34_02595	COG0616	signal peptide processing
HMY34_02595	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HMY34_02600	COG0546	phosphoglycolate phosphatase activity
HMY34_02610	COG1530	ribonuclease E activity
HMY34_02615	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HMY34_02620	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HMY34_02640	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HMY34_02650	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HMY34_02655	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HMY34_02660	COG0180	Tryptophanyl-tRNA synthetase
HMY34_02665	COG1994	Peptidase M50
HMY34_02670	COG0009	L-threonylcarbamoyladenylate synthase
HMY34_02675	COG2917	probably involved in intracellular septation
HMY34_02680	COG2350	Protein conserved in bacteria
HMY34_02685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HMY34_02695	COG0438	transferase activity, transferring glycosyl groups
HMY34_02705	COG0438	transferase activity, transferring glycosyl groups
HMY34_02740	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HMY34_02745	COG4181	ATPase activity
HMY34_02755	COG2308	Evidence 4 Homologs of previously reported genes of
HMY34_02770	COG3209	COG3209 Rhs family protein
HMY34_02820	COG5433	transposase activity
HMY34_02855	COG0515	serine threonine protein kinase
HMY34_02855	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HMY34_02895	COG3245	cytochrome
HMY34_02915	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HMY34_02940	COG0741	lytic transglycosylase activity
HMY34_02945	COG2833	Protein of unknown function (DUF455)
HMY34_02950	COG2379	hydroxypyruvate reductase
HMY34_02955	COG2197	response regulator
HMY34_03010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HMY34_03015	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HMY34_03025	COG1215	transferase activity, transferring glycosyl groups
HMY34_03030	COG3250	beta-galactosidase activity
HMY34_03040	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HMY34_03045	COG1366	Belongs to the anti-sigma-factor antagonist family
HMY34_03055	COG2205	protein histidine kinase activity
HMY34_03055	COG3850	Histidine kinase
HMY34_03055	COG3437	response regulator, receiver
HMY34_03055	COG4999	Histidine kinase
HMY34_03060	COG2208	phosphoserine phosphatase activity
HMY34_03125	COG1960	acyl-CoA dehydrogenase activity
HMY34_03135	COG0727	PFAM Uncharacterised protein family (UPF0153)
HMY34_03140	COG1858	cytochrome C peroxidase
HMY34_03150	COG2885	chlorophyll binding
HMY34_03160	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HMY34_03165	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HMY34_03175	COG0811	peptide transport
HMY34_03180	COG4774	siderophore transport
HMY34_03185	COG3128	pkhd-type hydroxylase
HMY34_03190	COG1840	ABC-type Fe3 transport system, periplasmic component
HMY34_03210	COG0450	alkyl hydroperoxide reductase
HMY34_03215	COG2119	membrane
HMY34_03220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMY34_03225	COG5002	protein histidine kinase activity
HMY34_03255	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
HMY34_03285	COG1858	cytochrome C peroxidase
HMY34_03290	COG2193	ferroxidase activity
HMY34_03325	COG0748	coenzyme F420 binding
HMY34_03330	COG4558	Periplasmic binding protein
HMY34_03335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HMY34_03340	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
HMY34_03345	COG3720	iron ion transport
HMY34_03395	COG1136	(ABC) transporter
HMY34_03395	COG0577	efflux transmembrane transporter activity
HMY34_03400	COG1566	PFAM secretion protein HlyD family protein
HMY34_03420	COG0745	RESPONSE REGULATOR receiver
HMY34_03425	COG2205	protein histidine kinase activity
HMY34_03430	COG1404	Belongs to the peptidase S8 family
HMY34_03445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HMY34_03455	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HMY34_03455	COG0069	glutamate synthase activity
HMY34_03465	COG1840	ABC-type Fe3 transport system, periplasmic component
HMY34_03470	COG1178	ABC-type Fe3 transport system permease component
HMY34_03475	COG3842	ATPase activity
HMY34_03485	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HMY34_03495	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HMY34_03500	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HMY34_03505	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMY34_03510	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMY34_03515	COG0195	Participates in both transcription termination and antitermination
HMY34_03515	COG2251	uridine kinase activity
HMY34_03520	COG0779	Required for maturation of 30S ribosomal subunits
HMY34_03535	COG1007	ATP synthesis coupled electron transport
HMY34_03550	COG0713	ATP synthesis coupled electron transport
HMY34_03560	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HMY34_03565	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HMY34_03570	COG1034	ATP synthesis coupled electron transport
HMY34_03585	COG0649	NAD binding
HMY34_03590	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HMY34_03595	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HMY34_03600	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HMY34_03610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HMY34_03615	COG0149	triose-phosphate isomerase activity
HMY34_03620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMY34_03625	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HMY34_03635	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
HMY34_03670	COG0493	'glutamate synthase
HMY34_03685	COG2920	part of a sulfur-relay system
HMY34_03690	COG2168	tRNA wobble position uridine thiolation
HMY34_03695	COG2923	Belongs to the DsrF TusC family
HMY34_03700	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HMY34_03705	COG2221	Nitrite and sulphite reductase 4Fe-4S
HMY34_03710	COG2221	Nitrite and sulphite reductase 4Fe-4S
HMY34_03745	COG3128	pkhd-type hydroxylase
HMY34_03770	COG2814	Major facilitator Superfamily
HMY34_03875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HMY34_03905	COG0066	3-isopropylmalate dehydratase activity
HMY34_03910	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HMY34_03920	COG4932	domain protein
HMY34_03960	COG0537	adenosine 5'-monophosphoramidase activity
HMY34_03965	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HMY34_03985	COG0745	RESPONSE REGULATOR receiver
HMY34_04000	COG0840	transmembrane signaling receptor activity
HMY34_04010	COG0745	RESPONSE REGULATOR receiver
HMY34_04040	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HMY34_04045	COG0741	lytic transglycosylase activity
HMY34_04045	COG1196	nuclear chromosome segregation
HMY34_04045	COG0739	heme binding
HMY34_04050	COG2975	iron-sulfur cluster assembly
HMY34_04060	COG0443	Heat shock 70 kDa protein
HMY34_04065	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
HMY34_04070	COG0316	Belongs to the HesB IscA family
HMY34_04075	COG0822	iron-sulfur transferase activity
HMY34_04080	COG1104	cysteine desulfurase activity
HMY34_04085	COG1959	2 iron, 2 sulfur cluster binding
HMY34_04135	COG0375	protein maturation
HMY34_04140	COG0778	Nitroreductase
HMY34_04155	COG1199	ATP-dependent helicase activity
HMY34_04165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HMY34_04185	COG2914	Belongs to the UPF0125 (RnfH) family
HMY34_04195	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HMY34_04200	COG0735	belongs to the Fur family
HMY34_04210	COG2197	response regulator
HMY34_04220	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HMY34_04225	COG1610	YqeY-like protein
HMY34_04230	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HMY34_04245	COG3850	Histidine kinase
HMY34_04260	COG2197	response regulator
HMY34_04265	COG0784	Response regulator, receiver
HMY34_04265	COG2198	Histidine kinase
HMY34_04265	COG5002	protein histidine kinase activity
HMY34_04320	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HMY34_04320	COG0515	serine threonine protein kinase
HMY34_04385	COG1672	PFAM Archaeal ATPase
HMY34_04385	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HMY34_04425	COG1286	toxin biosynthetic process
HMY34_04435	COG0285	dihydrofolate synthase activity
HMY34_04445	COG0159	tryptophan synthase activity
HMY34_04450	COG0133	tryptophan synthase activity
HMY34_04485	COG4636	protein conserved in cyanobacteria
HMY34_04515	COG0135	phosphoribosylanthranilate isomerase activity
HMY34_04520	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HMY34_04530	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HMY34_04550	COG1127	ABC transporter
HMY34_04555	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HMY34_04600	COG1519	Transferase
HMY34_04605	COG0859	PFAM glycosyl transferase family 9
HMY34_04610	COG1560	Kdo2-lipid A biosynthetic process
HMY34_04620	COG0859	PFAM glycosyl transferase family 9
HMY34_04625	COG0463	Glycosyl transferase, family 2
HMY34_04635	COG0667	Aldo Keto reductase
HMY34_04650	COG2996	Protein conserved in bacteria
HMY34_04660	COG3609	addiction module antidote protein, CC2985 family
HMY34_04695	COG2996	Protein conserved in bacteria
HMY34_04755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HMY34_04795	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HMY34_04860	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
HMY34_04895	COG0628	permease
HMY34_04900	COG0242	peptide deformylase activity
HMY34_04920	COG0598	Magnesium transport protein CorA
HMY34_04940	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HMY34_04945	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
HMY34_04945	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
HMY34_04950	COG2814	Major facilitator Superfamily
HMY34_04955	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HMY34_04970	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HMY34_04980	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HMY34_04985	COG5002	protein histidine kinase activity
HMY34_04985	COG5001	Diguanylate cyclase
HMY34_04990	COG0335	large ribosomal subunit rRNA binding
HMY34_05000	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HMY34_05005	COG0228	four-way junction DNA binding
HMY34_05010	COG3738	Protein conserved in bacteria
HMY34_05030	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HMY34_05035	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HMY34_05040	COG4536	flavin adenine dinucleotide binding
HMY34_05050	COG0513	Belongs to the DEAD box helicase family
HMY34_05060	COG0352	thiamine-phosphate diphosphorylase activity
HMY34_05065	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HMY34_05070	COG0653	protein targeting
HMY34_05075	COG1196	nuclear chromosome segregation
HMY34_05075	COG0741	lytic transglycosylase activity
HMY34_05075	COG0739	heme binding
HMY34_05085	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HMY34_05090	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HMY34_05100	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HMY34_05105	COG1181	Belongs to the D-alanine--D-alanine ligase family
HMY34_05110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HMY34_05115	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HMY34_05120	COG0772	Belongs to the SEDS family
HMY34_05125	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HMY34_05130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMY34_05135	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HMY34_05140	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HMY34_05155	COG0275	rRNA processing
HMY34_05160	COG2001	Belongs to the MraZ family
HMY34_05180	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HMY34_05205	COG0697	spore germination
HMY34_05215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMY34_05235	COG4245	von Willebrand factor, type A
HMY34_05270	COG0542	response to heat
HMY34_05275	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HMY34_05280	COG0697	spore germination
HMY34_05290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HMY34_05335	COG1715	Restriction endonuclease
HMY34_05370	COG1047	Peptidyl-prolyl cis-trans
HMY34_05375	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HMY34_05380	COG0483	inositol monophosphate 1-phosphatase activity
HMY34_05390	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HMY34_05395	COG1546	Belongs to the CinA family
HMY34_05395	COG1058	Belongs to the CinA family
HMY34_05445	COG4790	Type iii secretion
HMY34_05455	COG4791	protein targeting
HMY34_05460	COG4792	protein secretion
HMY34_05470	COG4789	Type iii secretion
HMY34_05500	COG5007	Belongs to the BolA IbaG family
HMY34_05505	COG1611	Belongs to the LOG family
HMY34_05515	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HMY34_05530	COG0174	glutamine synthetase
HMY34_05565	COG3852	Histidine kinase
HMY34_05590	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HMY34_05610	COG3220	belongs to the UPF0276 family
HMY34_05620	COG1234	tRNA 3'-trailer cleavage
HMY34_05640	COG0753	catalase activity
HMY34_05680	COG0659	secondary active sulfate transmembrane transporter activity
HMY34_05710	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
HMY34_05720	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMY34_05720	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HMY34_05725	COG0488	(ABC) transporter
HMY34_05730	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HMY34_05735	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HMY34_05760	COG0328	RNA-DNA hybrid ribonuclease activity
HMY34_05775	COG1716	ATPase activity
HMY34_05780	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HMY34_05795	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HMY34_05815	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HMY34_05820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HMY34_05840	COG0776	regulation of translation
HMY34_05845	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HMY34_05850	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMY34_05855	COG0740	serine-type endopeptidase activity
HMY34_05860	COG0544	peptidyl-prolyl cis-trans isomerase activity
HMY34_05885	COG1116	anion transmembrane transporter activity
HMY34_05890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HMY34_05895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HMY34_05910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HMY34_05930	COG2808	Putative FMN-binding domain
HMY34_05945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HMY34_05945	COG1116	anion transmembrane transporter activity
HMY34_05955	COG0346	lactoylglutathione lyase activity
HMY34_05970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HMY34_06010	COG0405	Gamma-glutamyltransferase
HMY34_06020	COG0243	molybdopterin cofactor binding
HMY34_06030	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HMY34_06085	COG1238	metal cluster binding
HMY34_06110	COG3243	poly(R)-hydroxyalkanoic acid synthase
HMY34_06120	COG0183	Belongs to the thiolase family
HMY34_06125	COG1028	Short-chain dehydrogenase reductase Sdr
HMY34_06130	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
HMY34_06200	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMY34_06205	COG1518	maintenance of DNA repeat elements
HMY34_06215	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HMY34_06240	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HMY34_06250	COG0316	Belongs to the HesB IscA family
HMY34_06265	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HMY34_06275	COG1981	membrane
HMY34_06285	COG1051	belongs to the nudix hydrolase family
HMY34_06295	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HMY34_06300	COG0438	transferase activity, transferring glycosyl groups
HMY34_06340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HMY34_06345	COG0784	Response regulator, receiver
HMY34_06345	COG5002	protein histidine kinase activity
HMY34_06375	COG0488	(ABC) transporter
HMY34_06390	COG0583	DNA-binding transcription factor activity
HMY34_06395	COG4464	protein tyrosine phosphatase activity
HMY34_06400	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMY34_06405	COG3156	type II secretion system protein K
HMY34_06415	COG2165	general secretion pathway protein
HMY34_06420	COG4970	Tfp pilus assembly protein FimT
HMY34_06430	COG1459	type II secretion system
HMY34_06435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HMY34_06495	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HMY34_06500	COG0142	geranyltranstransferase activity
HMY34_06505	COG1722	exodeoxyribonuclease VII activity
HMY34_06515	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
HMY34_06520	COG0237	dephospho-CoA kinase activity
HMY34_06525	COG0268	Binds directly to 16S ribosomal RNA
HMY34_06530	COG1475	DNA binding
HMY34_06535	COG1192	Involved in chromosome partitioning
HMY34_06540	COG0357	Ribosomal RNA small subunit methyltransferase G
HMY34_06545	COG0445	tRNA wobble uridine modification
HMY34_06550	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HMY34_06565	COG0202	RNA polymerase activity
HMY34_06570	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HMY34_06575	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HMY34_06580	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HMY34_06585	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HMY34_06590	COG0201	protein transport
HMY34_06595	COG0200	Binds to the 23S rRNA
HMY34_06600	COG1841	ribosomal large subunit assembly
HMY34_06610	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HMY34_06615	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HMY34_06620	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HMY34_06625	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HMY34_06630	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HMY34_06635	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HMY34_06640	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HMY34_06645	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HMY34_06650	COG0255	Belongs to the universal ribosomal protein uL29 family
HMY34_06655	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
HMY34_06665	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HMY34_06670	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HMY34_06675	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HMY34_06680	COG0089	rRNA binding
HMY34_06685	COG0088	Forms part of the polypeptide exit tunnel
HMY34_06690	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HMY34_06695	COG0051	transcription antitermination factor activity, RNA binding
HMY34_06705	COG0049	tRNA binding
HMY34_06710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HMY34_06720	COG0085	RNA polymerase activity
HMY34_06725	COG0222	ribosome binding
HMY34_06730	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HMY34_06735	COG0081	regulation of translation
HMY34_06740	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HMY34_06750	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HMY34_06760	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HMY34_06790	COG0729	surface antigen
HMY34_06795	COG2027	D-alanyl-D-alanine carboxypeptidase
HMY34_06800	COG1720	tRNA m6t6A37 methyltransferase activity
HMY34_06805	COG1434	Gram-negative-bacterium-type cell wall biogenesis
HMY34_06815	COG0748	coenzyme F420 binding
HMY34_06845	COG1858	cytochrome C peroxidase
HMY34_06850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HMY34_06855	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HMY34_06860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HMY34_06865	COG1121	(ABC) transporter
HMY34_06870	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
HMY34_06880	COG0019	diaminopimelate decarboxylase activity
HMY34_06895	COG0446	pyridine nucleotide-disulphide oxidoreductase
HMY34_06900	COG0617	tRNA 3'-terminal CCA addition
HMY34_06915	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HMY34_06965	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HMY34_06970	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HMY34_06975	COG1193	negative regulation of DNA recombination
HMY34_06995	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HMY34_07000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HMY34_07105	COG3655	Transcriptional regulator
HMY34_07110	COG0519	Catalyzes the synthesis of GMP from XMP
HMY34_07160	COG1187	pseudouridine synthase activity
HMY34_07165	COG3291	Pkd domain containing protein
HMY34_07185	COG0463	Glycosyl transferase, family 2
HMY34_07190	COG2076	Multidrug Resistance protein
HMY34_07195	COG2076	Multidrug Resistance protein
HMY34_07215	COG0183	Belongs to the thiolase family
HMY34_07220	COG1024	Enoyl-CoA hydratase
HMY34_07220	COG1250	3-hydroxyacyl-CoA dehydrogenase
HMY34_07225	COG0318	PFAM AMP-dependent synthetase and ligase
HMY34_07230	COG0037	tRNA processing
HMY34_07235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HMY34_07270	COG2852	Protein conserved in bacteria
HMY34_07295	COG3178	'Phosphotransferase
HMY34_07300	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HMY34_07305	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
HMY34_07310	COG1469	GTP cyclohydrolase I activity
HMY34_07325	COG1077	Cell shape determining protein MreB Mrl
HMY34_07330	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HMY34_07335	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HMY34_07340	COG0596	Alpha beta hydrolase
HMY34_07360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMY34_07365	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HMY34_07370	COG0154	amidase activity
HMY34_07390	COG5265	(ABC) transporter
HMY34_07415	COG2204	response regulator
HMY34_07420	COG1940	carbohydrate kinase activity
HMY34_07435	COG0517	IMP dehydrogenase activity
HMY34_07440	COG1944	ATP diphosphatase activity
HMY34_07460	COG3738	Protein conserved in bacteria
HMY34_07475	COG3028	Belongs to the UPF0307 family
HMY34_07480	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HMY34_07485	COG0194	GDP metabolic process
HMY34_07505	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HMY34_07540	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HMY34_07545	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
HMY34_07550	COG1104	cysteine desulfurase activity
HMY34_07565	COG3851	Histidine kinase
HMY34_07570	COG2197	response regulator
HMY34_07600	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HMY34_07605	COG2983	Belongs to the UPF0260 family
HMY34_07615	COG0583	DNA-binding transcription factor activity
HMY34_07620	COG2046	Belongs to the sulfate adenylyltransferase family
HMY34_07625	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
HMY34_07630	COG4804	nuclease activity
HMY34_07640	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMY34_07645	COG4191	Histidine kinase
HMY34_07650	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HMY34_07675	COG2268	Band 7 protein
HMY34_07725	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HMY34_07760	COG4628	conserved protein (DUF2132)
HMY34_07765	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HMY34_07780	COG3550	peptidyl-serine autophosphorylation
HMY34_07840	COG0515	serine threonine protein kinase
HMY34_07855	COG1690	Belongs to the RtcB family
HMY34_07865	COG3550	peptidyl-serine autophosphorylation
HMY34_07875	COG3001	Fructosamine kinase
HMY34_07900	COG1388	LysM domain
HMY34_07900	COG1705	Flagellar rod assembly protein muramidase FlgJ
HMY34_07910	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HMY34_07930	COG4650	regulator
HMY34_08000	COG0604	alcohol dehydrogenase
HMY34_08010	COG2204	response regulator
HMY34_08020	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HMY34_08025	COG2027	D-alanyl-D-alanine carboxypeptidase
HMY34_08035	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HMY34_08040	COG3954	Phosphoribulokinase
HMY34_08070	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HMY34_08070	COG0116	Belongs to the methyltransferase superfamily
HMY34_08090	COG0741	lytic transglycosylase activity
HMY34_08115	COG0330	HflC and HflK could
HMY34_08125	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HMY34_08140	COG0009	L-threonylcarbamoyladenylate synthase
HMY34_08150	COG0513	Belongs to the DEAD box helicase family
HMY34_08160	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMY34_08175	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HMY34_08190	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HMY34_08220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HMY34_08225	COG4215	(ABC) transporter
HMY34_08250	COG1032	radical SAM domain protein
HMY34_08290	COG2197	response regulator
HMY34_08295	COG4232	protein-disulfide reductase activity
HMY34_08315	COG0697	spore germination
HMY34_08415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HMY34_08415	COG0543	2 iron, 2 sulfur cluster binding
HMY34_08420	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HMY34_08510	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HMY34_08515	COG0860	N-Acetylmuramoyl-L-alanine amidase
HMY34_08520	COG0802	atpase or kinase
HMY34_08550	COG1643	Atp-dependent helicase
HMY34_08565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HMY34_08570	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HMY34_08575	COG1216	Glycosyl transferase, family 2
HMY34_08605	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HMY34_08610	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HMY34_08615	COG2255	four-way junction helicase activity
HMY34_08620	COG0824	Thioesterase
HMY34_08625	COG0811	peptide transport
HMY34_08645	COG2885	chlorophyll binding
HMY34_08695	COG0477	Major facilitator Superfamily
HMY34_08700	COG1131	(ABC) transporter
HMY34_08720	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HMY34_08755	COG1061	Type III restriction enzyme res subunit
HMY34_08795	COG0537	adenosine 5'-monophosphoramidase activity
HMY34_08835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMY34_08855	COG0751	glycine-tRNA ligase activity
HMY34_08860	COG0697	spore germination
HMY34_08865	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HMY34_08885	COG2319	Wd-40 repeat
HMY34_08885	COG3903	Transcriptional regulator
HMY34_08930	COG0129	dihydroxy-acid dehydratase activity
HMY34_08950	COG2205	protein histidine kinase activity
HMY34_08955	COG0745	RESPONSE REGULATOR receiver
HMY34_08960	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HMY34_08980	COG0488	(ABC) transporter
HMY34_08985	COG3177	Filamentation induced by cAMP protein fic
HMY34_08990	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HMY34_09005	COG1252	NADH dehydrogenase
HMY34_09020	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HMY34_09025	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HMY34_09050	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HMY34_09060	COG2813	Specifically methylates the guanine in position
HMY34_09065	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HMY34_09070	COG1595	DNA-templated transcription, initiation
HMY34_09080	COG1404	Belongs to the peptidase S8 family
HMY34_09100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HMY34_09105	COG0730	response to heat
HMY34_09125	COG1587	Uroporphyrinogen-III synthase
HMY34_09140	COG0281	malic enzyme
HMY34_09145	COG4783	chaperone-mediated protein folding
HMY34_09155	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HMY34_09210	COG0840	transmembrane signaling receptor activity
HMY34_09240	COG0084	hydrolase, TatD family'
HMY34_09245	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HMY34_09255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMY34_09275	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HMY34_09280	COG0540	Belongs to the ATCase OTCase family
HMY34_09340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HMY34_09350	COG2161	toxin-antitoxin pair type II binding
HMY34_09355	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HMY34_09370	COG0058	SHG alpha-glucan phosphorylase activity
HMY34_09375	COG0297	glycogen (starch) synthase activity
HMY34_09380	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HMY34_09385	COG1640	4-alpha-glucanotransferase
HMY34_09395	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HMY34_09405	COG0166	Belongs to the GPI family
HMY34_09415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HMY34_09435	COG2204	response regulator
HMY34_09440	COG5000	phosphorelay sensor kinase activity
HMY34_09450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMY34_09450	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HMY34_09465	COG1652	LysM domain
HMY34_09475	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HMY34_09495	COG3956	TIGRFAM MazG family protein
HMY34_09500	COG0632	four-way junction helicase activity
HMY34_09505	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HMY34_09510	COG0217	transcriptional regulatory protein
HMY34_09515	COG1002	Type II restriction enzyme, methylase subunits
HMY34_09525	COG1773	rubredoxin
HMY34_09550	COG0179	Fumarylacetoacetate (FAA) hydrolase
HMY34_09560	COG1136	(ABC) transporter
HMY34_09565	COG4662	Binding-protein-dependent transport system inner membrane component
HMY34_09590	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HMY34_09615	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
HMY34_09640	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HMY34_09650	COG0585	pseudouridine synthase activity
HMY34_09660	COG2205	protein histidine kinase activity
HMY34_09660	COG2198	Histidine kinase
HMY34_09660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HMY34_09660	COG0784	Response regulator, receiver
HMY34_09670	COG2198	Histidine kinase
HMY34_09670	COG0784	Response regulator, receiver
HMY34_09670	COG2205	protein histidine kinase activity
HMY34_09695	COG1139	Iron-sulfur cluster binding protein
HMY34_09700	COG0247	lactate metabolic process
HMY34_09705	COG2186	Transcriptional regulator
HMY34_09715	COG0277	FAD linked oxidase domain protein
HMY34_09740	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
HMY34_09745	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HMY34_09750	COG0131	Imidazoleglycerol-phosphate dehydratase
HMY34_09765	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HMY34_09780	COG0758	DNA mediated transformation
HMY34_09785	COG2922	Belongs to the Smg family
HMY34_09790	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HMY34_09810	COG4681	YaeQ
HMY34_09820	COG3302	dmso reductase anchor subunit
HMY34_09825	COG0437	4 iron, 4 sulfur cluster binding
HMY34_09830	COG0243	molybdopterin cofactor binding
HMY34_09860	COG2133	pyrroloquinoline quinone binding
HMY34_09885	COG4181	ATPase activity
HMY34_09890	COG4628	conserved protein (DUF2132)
HMY34_09915	COG1752	Esterase of the alpha-beta hydrolase superfamily
HMY34_09930	COG0708	Exodeoxyribonuclease III
HMY34_09935	COG0339	signal peptide processing
HMY34_09945	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMY34_09950	COG0592	DNA-directed DNA polymerase activity
HMY34_09955	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HMY34_09960	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HMY34_09965	COG0594	ribonuclease P activity
HMY34_09970	COG0706	membrane insertase activity
HMY34_09975	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMY34_10015	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HMY34_10020	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HMY34_10060	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HMY34_10070	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HMY34_10075	COG0425	Belongs to the sulfur carrier protein TusA family
HMY34_10080	COG0156	8-amino-7-oxononanoate synthase activity
HMY34_10125	COG0521	Mo-molybdopterin cofactor biosynthetic process
HMY34_10140	COG1690	Belongs to the RtcB family
HMY34_10170	COG0489	protein tyrosine kinase activity
HMY34_10190	COG0301	tRNA thio-modification
HMY34_10195	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
HMY34_10245	COG0488	(ABC) transporter
HMY34_10250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HMY34_10265	COG1678	Uncharacterized ACR, COG1678
HMY34_10270	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HMY34_10280	COG0406	alpha-ribazole phosphatase activity
HMY34_10290	COG1595	DNA-templated transcription, initiation
HMY34_10335	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HMY34_10340	COG0196	riboflavin kinase activity
HMY34_10345	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HMY34_10365	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HMY34_10385	COG3220	belongs to the UPF0276 family
HMY34_10410	COG0270	DNA (cytosine-5-)-methyltransferase activity
HMY34_10415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HMY34_10425	COG0235	Class ii aldolase
HMY34_10430	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HMY34_10435	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
HMY34_10440	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HMY34_10445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HMY34_10460	COG0315	cyclic pyranopterin monophosphate synthase activity
HMY34_10465	COG0793	Belongs to the peptidase S41A family
HMY34_10490	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
HMY34_10495	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HMY34_10510	COG1765	OsmC-like protein
HMY34_10515	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HMY34_10520	COG0791	NLP P60 protein
HMY34_10530	COG1592	Rubrerythrin
HMY34_10545	COG5002	protein histidine kinase activity
HMY34_10545	COG2198	Histidine kinase
HMY34_10545	COG0784	Response regulator, receiver
HMY34_10560	COG0142	geranyltranstransferase activity
HMY34_10565	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HMY34_10570	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HMY34_10575	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HMY34_10580	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HMY34_10585	COG2967	ApaG domain
HMY34_10590	COG0739	heme binding
HMY34_10590	COG1196	nuclear chromosome segregation
HMY34_10590	COG0741	lytic transglycosylase activity
HMY34_10640	COG5002	protein histidine kinase activity
HMY34_10645	COG0745	RESPONSE REGULATOR receiver
HMY34_10650	COG5002	protein histidine kinase activity
HMY34_10650	COG2176	DNA-directed DNA polymerase activity
HMY34_10655	COG1758	RNA polymerase activity
HMY34_10660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HMY34_10675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMY34_10680	COG2210	Belongs to the sulfur carrier protein TusA family
HMY34_10690	COG1408	metallophosphoesterase
HMY34_10710	COG0840	transmembrane signaling receptor activity
HMY34_10720	COG0784	Response regulator, receiver
HMY34_10720	COG0643	Histidine kinase
HMY34_10720	COG2198	Histidine kinase
HMY34_10735	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HMY34_10770	COG0500	methyltransferase
HMY34_10780	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HMY34_10800	COG1056	cytidyltransferase-related domain
HMY34_10800	COG1051	belongs to the nudix hydrolase family
HMY34_10810	COG0783	Belongs to the Dps family
HMY34_10820	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HMY34_10840	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
HMY34_10845	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
HMY34_10860	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HMY34_10875	COG3609	addiction module antidote protein, CC2985 family
HMY34_10940	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HMY34_10950	COG3002	Belongs to the UPF0753 family
HMY34_10955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HMY34_10960	COG3002	Belongs to the UPF0753 family
HMY34_10975	COG1538	Outer membrane efflux protein
HMY34_10985	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HMY34_11070	COG2918	glutathione biosynthetic process
HMY34_11075	COG0724	RNA recognition motif
HMY34_11080	COG1872	DUF167
HMY34_11085	COG0762	integral membrane protein
HMY34_11100	COG0826	peptidase U32
HMY34_11105	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HMY34_11135	COG0732	type I restriction modification DNA specificity domain
HMY34_11140	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HMY34_11140	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HMY34_11165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HMY34_11170	COG2046	Belongs to the sulfate adenylyltransferase family
HMY34_11185	COG0563	adenylate kinase activity
HMY34_11190	COG1047	Peptidyl-prolyl cis-trans
HMY34_11200	COG0205	6-phosphofructokinase activity
HMY34_11210	COG0724	RNA recognition motif
HMY34_11225	COG2048	Heterodisulfide reductase, subunit B
HMY34_11230	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HMY34_11240	COG1233	COG1233 Phytoene dehydrogenase and related
HMY34_11245	COG0123	including yeast histone deacetylase and acetoin utilization protein
HMY34_11255	COG0351	phosphomethylpyrimidine kinase
HMY34_11270	COG0352	thiamine-phosphate diphosphorylase activity
HMY34_11280	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HMY34_11285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMY34_11295	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HMY34_11300	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HMY34_11305	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HMY34_11310	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HMY34_11315	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HMY34_11320	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HMY34_11325	COG0126	phosphoglycerate kinase activity
HMY34_11345	COG1902	pentaerythritol trinitrate reductase activity
HMY34_11365	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HMY34_11375	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HMY34_11380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HMY34_11385	COG0140	phosphoribosyl-ATP diphosphatase activity
HMY34_11395	COG0107	imidazoleglycerol-phosphate synthase activity
HMY34_11410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HMY34_11420	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HMY34_11430	COG0259	pyridoxamine-phosphate oxidase activity
HMY34_11450	COG0210	DNA helicase
HMY34_11465	COG0270	DNA (cytosine-5-)-methyltransferase activity
HMY34_11480	COG1671	Belongs to the UPF0178 family
HMY34_11490	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HMY34_11495	COG0640	Transcriptional regulator
HMY34_11510	COG3245	cytochrome
HMY34_11515	COG1132	(ABC) transporter
HMY34_11520	COG4452	Inner membrane protein CreD
HMY34_11525	COG0402	S-adenosylhomocysteine deaminase activity
HMY34_11535	COG1079	Belongs to the binding-protein-dependent transport system permease family
HMY34_11540	COG4603	Belongs to the binding-protein-dependent transport system permease family
HMY34_11545	COG3845	ABC transporter
HMY34_11555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HMY34_11560	COG2080	2 iron, 2 sulfur cluster binding
HMY34_11570	COG1309	transcriptional regulator
HMY34_11575	COG2351	hydroxyisourate hydrolase activity
HMY34_11595	COG4266	Belongs to the allantoicase family
HMY34_11600	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
HMY34_11605	COG2233	PERMEase
HMY34_11625	COG0831	urea catabolic process
HMY34_11630	COG0832	Belongs to the urease beta subunit family
HMY34_11635	COG0804	urea catabolic process
HMY34_11645	COG3645	SOS response
HMY34_11655	COG4804	nuclease activity
HMY34_11680	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
HMY34_11690	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HMY34_11695	COG0830	nickel cation binding
HMY34_11715	COG0004	ammonium transporteR
HMY34_11730	COG3297	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
HMY34_11735	COG3156	type II secretion system protein K
HMY34_11750	COG1162	GTPase activity
HMY34_11760	COG0501	Belongs to the peptidase M48B family
HMY34_11765	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HMY34_11795	COG0714	Associated with various cellular activities
HMY34_11810	COG2354	Protein conserved in bacteria
HMY34_11820	COG1490	D-aminoacyl-tRNA deacylase activity
HMY34_11835	COG1028	Short-chain dehydrogenase reductase Sdr
HMY34_11880	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HMY34_11880	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
HMY34_11885	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
HMY34_11890	COG0792	nuclease activity
HMY34_11895	COG3107	peptidoglycan biosynthetic process
HMY34_11900	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HMY34_11905	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HMY34_11915	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HMY34_11920	COG0768	penicillin binding
HMY34_11925	COG0772	Belongs to the SEDS family
HMY34_11930	COG2951	lytic endotransglycosylase activity
HMY34_11940	COG1686	Belongs to the peptidase S11 family
HMY34_11945	COG2921	Belongs to the UPF0250 family
HMY34_11950	COG0321	lipoyl(octanoyl) transferase activity
HMY34_11955	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
HMY34_11965	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HMY34_11970	COG1333	cytochrome c biogenesis protein
HMY34_11980	COG0218	Necessary for normal cell division and for the maintenance of normal septation
HMY34_11985	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMY34_11995	COG1561	YicC-like family, N-terminal region
HMY34_12010	COG2165	general secretion pathway protein
HMY34_12020	COG2165	general secretion pathway protein
HMY34_12035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HMY34_12065	COG1477	protein flavinylation
HMY34_12110	COG2194	sulfuric ester hydrolase activity
HMY34_12115	COG3038	cytochrome b561
HMY34_12135	COG0446	pyridine nucleotide-disulphide oxidoreductase
HMY34_12235	COG3850	Histidine kinase
HMY34_12235	COG2205	protein histidine kinase activity
HMY34_12235	COG4999	Histidine kinase
HMY34_12235	COG3437	response regulator, receiver
HMY34_12265	COG1450	Type ii and iii secretion system protein
HMY34_12280	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HMY34_12305	COG1215	transferase activity, transferring glycosyl groups
HMY34_12320	COG1215	transferase activity, transferring glycosyl groups
HMY34_12330	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
HMY34_12335	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HMY34_12350	COG4636	protein conserved in cyanobacteria
HMY34_12355	COG0247	lactate metabolic process
HMY34_12365	COG0004	ammonium transporteR
HMY34_12390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HMY34_12405	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
HMY34_12410	COG2873	o-acetylhomoserine
HMY34_12415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HMY34_12425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMY34_12460	COG0018	arginyl-trna synthetase
HMY34_12510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMY34_12520	COG1218	3'(2'),5'-bisphosphate nucleotidase
HMY34_12535	COG0494	nUDIX hydrolase
HMY34_12545	COG1011	Hydrolase
HMY34_12555	COG0675	Transposase, IS605 OrfB family
HMY34_12565	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HMY34_12565	COG1017	nitric oxide dioxygenase activity
HMY34_12575	COG4191	Histidine kinase
HMY34_12605	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HMY34_12610	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HMY34_12640	COG1850	ribulose-bisphosphate carboxylase activity
HMY34_12660	COG1196	nuclear chromosome segregation
HMY34_12675	COG0009	L-threonylcarbamoyladenylate synthase
HMY34_12685	COG0583	DNA-binding transcription factor activity
HMY34_12690	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HMY34_12730	COG0651	ATP synthesis coupled electron transport
HMY34_12735	COG0651	ATP synthesis coupled electron transport
HMY34_12740	COG0651	ATP synthesis coupled electron transport
HMY34_12775	COG3876	Protein conserved in bacteria
HMY34_12820	COG1805	sodium ion transport
HMY34_12830	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
HMY34_12840	COG2871	sodium ion transport
HMY34_12850	COG0617	tRNA 3'-terminal CCA addition
HMY34_12850	COG0517	IMP dehydrogenase activity
HMY34_12850	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HMY34_12865	COG1047	Peptidyl-prolyl cis-trans
HMY34_12875	COG0151	Belongs to the GarS family
HMY34_12970	COG0426	domain, Protein
HMY34_12975	COG0633	Ferredoxin
HMY34_12985	COG1943	Transposase
HMY34_13010	COG1959	2 iron, 2 sulfur cluster binding
HMY34_13045	COG1643	Atp-dependent helicase
HMY34_13065	COG4657	Part of a membrane complex involved in electron transport
HMY34_13070	COG2878	Part of a membrane complex involved in electron transport
HMY34_13110	COG4658	electron transport chain
HMY34_13125	COG2914	Belongs to the UPF0125 (RnfH) family
HMY34_13135	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMY34_13160	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HMY34_13215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HMY34_13230	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HMY34_13265	COG0732	type I restriction modification DNA specificity domain
HMY34_13270	COG4804	nuclease activity
HMY34_13280	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
HMY34_13355	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HMY34_13375	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
HMY34_13395	COG1217	gtp-binding protein TYPA
HMY34_13445	COG2346	COG2346, Truncated hemoglobins
HMY34_13470	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HMY34_13475	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HMY34_13480	COG0784	Response regulator, receiver
HMY34_13480	COG5002	protein histidine kinase activity
HMY34_13520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HMY34_13525	COG1923	regulation of RNA biosynthetic process
HMY34_13530	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HMY34_13535	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HMY34_13540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMY34_13545	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HMY34_13550	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HMY34_13555	COG0165	Argininosuccinate lyase
HMY34_13560	COG3275	phosphorelay sensor kinase activity
HMY34_13580	COG0356	it plays a direct role in the translocation of protons across the membrane
HMY34_13585	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMY34_13590	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HMY34_13595	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HMY34_13600	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HMY34_13605	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HMY34_13610	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HMY34_13615	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HMY34_13630	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HMY34_13655	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HMY34_13685	COG1166	arginine decarboxylase activity
HMY34_13695	COG3100	YcgL domain-containing protein
HMY34_13750	COG0494	nUDIX hydrolase
HMY34_13760	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HMY34_13770	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HMY34_13775	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HMY34_13780	COG1492	cobalamin metabolic process
HMY34_13790	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HMY34_13795	COG0778	Nitroreductase
HMY34_13810	COG4206	TonB-dependent receptor
HMY34_13815	COG3591	Belongs to the peptidase S1B family
HMY34_13815	COG1864	DNA RNA non-specific endonuclease
HMY34_13825	COG2226	methyltransferase
HMY34_13840	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HMY34_13845	COG0675	Transposase, IS605 OrfB family
HMY34_13855	COG0671	phosphoesterase, PA-phosphatase related
HMY34_13865	COG0084	hydrolase, TatD family'
HMY34_13890	COG0367	asparagine synthase
HMY34_13910	COG0577	efflux transmembrane transporter activity
HMY34_13920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HMY34_13925	COG1999	signal sequence binding
HMY34_13935	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HMY34_13940	COG0109	protoheme IX farnesyltransferase activity
HMY34_13970	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
HMY34_13980	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HMY34_13985	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HMY34_13995	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HMY34_14000	COG1612	heme a metabolic process
HMY34_14005	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HMY34_14010	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HMY34_14015	COG0708	Exodeoxyribonuclease III
HMY34_14020	COG1752	Esterase of the alpha-beta hydrolase superfamily
HMY34_14030	COG3038	cytochrome b561
HMY34_14035	COG1741	Belongs to the pirin family
HMY34_14040	COG0583	DNA-binding transcription factor activity
HMY34_14045	COG0586	Pfam SNARE associated Golgi protein
HMY34_14050	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
HMY34_14055	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HMY34_14060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HMY34_14065	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
HMY34_14070	COG1234	tRNA 3'-trailer cleavage
HMY34_14155	COG0795	lipopolysaccharide-transporting ATPase activity
HMY34_14170	COG0463	Glycosyl transferase, family 2
HMY34_14180	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HMY34_14195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HMY34_14245	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HMY34_14265	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HMY34_14270	COG1373	ATPase (AAA superfamily
HMY34_14275	COG3122	Protein conserved in bacteria
HMY34_14280	COG0724	RNA recognition motif
HMY34_14285	COG1278	Cold shock
HMY34_14340	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
HMY34_14385	COG2943	transferase activity, transferring hexosyl groups
HMY34_14395	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
HMY34_14405	COG2226	methyltransferase
HMY34_14460	COG4969	Belongs to the N-Me-Phe pilin family
HMY34_14475	COG2002	toxin-antitoxin pair type II binding
HMY34_14485	COG4636	protein conserved in cyanobacteria
HMY34_14500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HMY34_14500	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HMY34_14510	COG1444	tRNA N-acetyltransferase activity
HMY34_14520	COG1968	undecaprenyl-diphosphatase activity
HMY34_14540	COG1131	(ABC) transporter
HMY34_14580	COG0747	negative chemotaxis
HMY34_14625	COG0500	methyltransferase
HMY34_14640	COG3206	protein involved in exopolysaccharide biosynthesis
HMY34_14640	COG0489	protein tyrosine kinase activity
HMY34_14650	COG4464	protein tyrosine phosphatase activity
HMY34_14695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMY34_14715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HMY34_14750	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HMY34_14805	COG2089	acid synthase
HMY34_14820	COG1083	cytidylyl-transferase
HMY34_14825	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HMY34_14830	COG1086	Polysaccharide biosynthesis protein
HMY34_14840	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
HMY34_14845	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HMY34_14885	COG0601	transmembrane transport
HMY34_14890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMY34_14905	COG2177	Part of the ABC transporter FtsEX involved in
HMY34_14910	COG2884	Cell division ATP-binding protein ftsE
HMY34_14915	COG0552	protein localization to endoplasmic reticulum
HMY34_14920	COG0612	Peptidase, M16
HMY34_14925	COG0612	Peptidase, M16
HMY34_14930	COG0742	ribosomal rna small subunit methyltransferase
HMY34_14935	COG0791	NLP P60 protein
HMY34_14960	COG2304	oxidoreductase activity
HMY34_14990	COG0714	Associated with various cellular activities
HMY34_14995	COG2814	Major facilitator Superfamily
HMY34_15005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HMY34_15005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMY34_15040	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HMY34_15075	COG4232	protein-disulfide reductase activity
HMY34_15115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HMY34_15130	COG0730	response to heat
HMY34_15135	COG1160	GTP binding
HMY34_15140	COG2816	NAD+ diphosphatase activity
HMY34_15155	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HMY34_15160	COG0583	DNA-binding transcription factor activity
HMY34_15165	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HMY34_15175	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HMY34_15180	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HMY34_15185	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HMY34_15200	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HMY34_15225	COG1473	amidohydrolase
HMY34_15235	COG2951	lytic endotransglycosylase activity
HMY34_15240	COG0598	Magnesium transport protein CorA
HMY34_15245	COG1660	Displays ATPase and GTPase activities
HMY34_15250	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HMY34_15265	COG1137	ATPase activity
HMY34_15280	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HMY34_15285	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HMY34_15285	COG0517	IMP dehydrogenase activity
HMY34_15295	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HMY34_15305	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HMY34_15310	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
HMY34_15320	COG0583	DNA-binding transcription factor activity
HMY34_15335	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HMY34_15340	COG1183	phosphatidylcholine synthase activity
HMY34_15345	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HMY34_15350	COG1573	uracil-dna glycosylase
HMY34_15365	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HMY34_15370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HMY34_15380	COG1309	transcriptional regulator
HMY34_15420	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMY34_15425	COG2171	N-acyltransferase activity
HMY34_15435	COG0741	lytic transglycosylase activity
HMY34_15445	COG0811	peptide transport
HMY34_15450	COG0848	biopolymer transport protein
HMY34_15455	COG1132	(ABC) transporter
HMY34_15460	COG1663	tetraacyldisaccharide 4'-kinase activity
HMY34_15465	COG2835	tetraacyldisaccharide 4'-kinase activity
HMY34_15470	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
HMY34_15490	COG0579	oxidoreductase
HMY34_15500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HMY34_15515	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
HMY34_15520	COG0137	argininosuccinate synthase activity
HMY34_15525	COG2900	Belongs to the SlyX family
HMY34_15530	COG0742	ribosomal rna small subunit methyltransferase
HMY34_15535	COG2363	Small membrane protein
HMY34_15540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HMY34_15545	COG1959	2 iron, 2 sulfur cluster binding
HMY34_15555	COG0033	Phosphoglucomutase
HMY34_15565	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
HMY34_15575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HMY34_15580	COG1459	type II secretion system
HMY34_15610	COG0681	Belongs to the peptidase S26 family
HMY34_15615	COG1203	CRISPR-associated helicase, Cas3
HMY34_15640	COG1857	crispr-associated protein
HMY34_15655	COG1518	maintenance of DNA repeat elements
HMY34_15660	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HMY34_15680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HMY34_15680	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HMY34_15690	COG3245	cytochrome
HMY34_15700	COG0582	viral genome integration into host DNA
HMY34_15720	COG0429	hydrolase of the alpha beta-hydrolase fold
HMY34_15745	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMY34_15755	COG0723	plastoquinol--plastocyanin reductase activity
HMY34_15760	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HMY34_15765	COG2857	Cytochrome c1
HMY34_15770	COG0625	glutathione transferase activity
HMY34_15775	COG2969	positive regulation of protein catabolic process
HMY34_15785	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HMY34_15790	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HMY34_15825	COG2890	protein-(glutamine-N5) methyltransferase activity
HMY34_15830	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HMY34_15835	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HMY34_15845	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HMY34_15850	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HMY34_15860	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HMY34_15865	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HMY34_15870	COG0193	aminoacyl-tRNA hydrolase activity
HMY34_15875	COG0012	GTP binding
HMY34_15885	COG2814	Major facilitator Superfamily
HMY34_15910	COG1373	ATPase (AAA superfamily
HMY34_15920	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
HMY34_15935	COG0842	Transport permease protein
HMY34_15940	COG1131	(ABC) transporter
HMY34_15955	COG1373	ATPase (AAA superfamily
HMY34_15970	COG0024	Methionine aminopeptidase
HMY34_15975	COG0052	Belongs to the universal ribosomal protein uS2 family
HMY34_15980	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HMY34_15985	COG0528	UMP kinase activity
HMY34_15990	COG0233	cytoplasmic translational termination
HMY34_15995	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HMY34_16000	COG0575	Belongs to the CDS family
HMY34_16010	COG0750	zinc metalloprotease
HMY34_16015	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HMY34_16025	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HMY34_16030	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HMY34_16035	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HMY34_16040	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HMY34_16070	COG0489	protein tyrosine kinase activity
HMY34_16075	COG0505	Belongs to the CarA family
HMY34_16080	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HMY34_16085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HMY34_16090	COG0406	alpha-ribazole phosphatase activity
HMY34_16110	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HMY34_16130	COG3118	belongs to the thioredoxin family
HMY34_16135	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HMY34_16140	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMY34_16145	COG0517	IMP dehydrogenase activity
HMY34_16145	COG0516	GMP reductase activity
HMY34_16170	COG2373	Large extracellular alpha-helical protein
HMY34_16175	COG4953	penicillin-binding protein 1C
HMY34_16195	COG2850	peptidyl-arginine hydroxylation
HMY34_16200	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HMY34_16230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HMY34_16240	COG0481	GTPase activity
HMY34_16245	COG0681	Belongs to the peptidase S26 family
HMY34_16255	COG0571	ribonuclease III activity
HMY34_16260	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HMY34_16265	COG1381	Involved in DNA repair and RecF pathway recombination
HMY34_16270	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HMY34_16285	COG0736	holo-[acyl-carrier-protein] synthase activity
HMY34_16295	COG0784	Response regulator, receiver
HMY34_16295	COG2198	Histidine kinase
HMY34_16295	COG2205	protein histidine kinase activity
HMY34_16320	COG2184	nucleotidyltransferase activity
HMY34_16385	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HMY34_16395	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HMY34_16400	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HMY34_16435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HMY34_16465	COG1850	ribulose-bisphosphate carboxylase activity
HMY34_16500	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HMY34_16505	COG0077	Prephenate dehydratase
HMY34_16505	COG1605	Chorismate mutase
HMY34_16510	COG0519	Catalyzes the synthesis of GMP from XMP
HMY34_16510	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HMY34_16515	COG1028	Short-chain dehydrogenase reductase Sdr
HMY34_16525	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HMY34_16540	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HMY34_16545	COG0402	S-adenosylhomocysteine deaminase activity
HMY34_16550	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HMY34_16565	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HMY34_16570	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HMY34_16600	COG1132	(ABC) transporter
HMY34_16615	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HMY34_16630	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HMY34_16635	COG0688	phosphatidylethanolamine metabolic process
HMY34_16645	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HMY34_16650	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HMY34_16655	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HMY34_16660	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HMY34_16680	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HMY34_16695	COG3153	acetyltransferase
HMY34_16695	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HMY34_16750	COG0442	prolyl-tRNA aminoacylation
HMY34_16755	COG0446	pyridine nucleotide-disulphide oxidoreductase
HMY34_16765	COG1294	oxidase, subunit
HMY34_16770	COG4890	Cyd operon protein YbgT
HMY34_16775	COG4988	ABC transporter
HMY34_16780	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
HMY34_16785	COG0676	glucose-6-phosphate 1-epimerase activity
HMY34_16790	COG0415	Belongs to the DNA photolyase family
HMY34_16805	COG1652	LysM domain
HMY34_16810	COG0791	NLP P60 protein
HMY34_16835	COG3853	Toxic anion resistance protein (TelA)
HMY34_16845	COG0739	heme binding
HMY34_16850	COG0436	Aminotransferase
HMY34_16855	COG2321	neutral zinc metallopeptidase
HMY34_16890	COG0436	Aminotransferase
HMY34_16915	COG0438	transferase activity, transferring glycosyl groups
HMY34_16925	COG3206	protein involved in exopolysaccharide biosynthesis
HMY34_16925	COG0489	protein tyrosine kinase activity
HMY34_16930	COG0493	'glutamate synthase
HMY34_16935	COG0067	glutamate synthase
HMY34_16935	COG0070	glutamate synthase
HMY34_16935	COG0069	glutamate synthase activity
HMY34_17015	COG2197	response regulator
HMY34_17020	COG3850	Histidine kinase
HMY34_17050	COG2223	nitrite transmembrane transporter activity
HMY34_17055	COG2920	part of a sulfur-relay system
HMY34_17060	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
HMY34_17065	COG1140	nitrate reductase beta subunit
HMY34_17070	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
HMY34_17075	COG2181	nitrate reductase activity
HMY34_17080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HMY34_17085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HMY34_17125	COG2346	COG2346, Truncated hemoglobins
HMY34_17135	COG2920	part of a sulfur-relay system
HMY34_17145	COG1136	(ABC) transporter
HMY34_17145	COG0577	efflux transmembrane transporter activity
HMY34_17160	COG1309	transcriptional regulator
HMY34_17185	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HMY34_17190	COG0546	phosphoglycolate phosphatase activity
HMY34_17220	COG0564	pseudouridine synthase activity
HMY34_17230	COG4608	Belongs to the ABC transporter superfamily
HMY34_17235	COG1555	photosystem II stabilization
HMY34_17240	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HMY34_17250	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HMY34_17260	COG3842	ATPase activity
HMY34_17265	COG1176	ABC-type spermidine putrescine transport system, permease component I
HMY34_17270	COG1177	transmembrane transport
HMY34_17280	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HMY34_17295	COG0508	dehydrogenase complex catalyzes the overall conversion of
HMY34_17300	COG0508	dehydrogenase complex catalyzes the overall conversion of
HMY34_17305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HMY34_17310	COG2264	protein methyltransferase activity
HMY34_17390	COG0489	protein tyrosine kinase activity
HMY34_17405	COG0167	dihydroorotate dehydrogenase activity
HMY34_17420	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HMY34_17450	COG1074	ATP-dependent DNA helicase activity
HMY34_17455	COG0730	response to heat
HMY34_17485	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HMY34_17490	COG4660	Part of a membrane complex involved in electron transport
HMY34_17495	COG4659	FMN binding
HMY34_17505	COG4656	Part of a membrane complex involved in electron transport
HMY34_17510	COG2878	Part of a membrane complex involved in electron transport
HMY34_17515	COG4657	Part of a membrane complex involved in electron transport
HMY34_17520	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HMY34_17545	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HMY34_17555	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
HMY34_17560	COG0424	maF-like protein
HMY34_17575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HMY34_17580	COG0312	modulator of DNA gyrase
HMY34_17585	COG0312	modulator of DNA gyrase
HMY34_17590	COG3123	guanosine phosphorylase activity
HMY34_17595	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HMY34_17600	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HMY34_17610	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HMY34_17615	COG0348	domain, Protein
HMY34_17625	COG2217	Heavy metal translocating P-type atpase
HMY34_17655	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HMY34_17665	COG0602	queuosine metabolic process
HMY34_17670	COG0720	synthase
HMY34_17705	COG0500	methyltransferase
HMY34_17730	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HMY34_17740	COG3115	cell septum assembly
HMY34_17785	COG2205	protein histidine kinase activity
HMY34_17790	COG0745	RESPONSE REGULATOR receiver
HMY34_17795	COG3158	transport of potassium into the cell
HMY34_17810	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HMY34_17815	COG0784	Response regulator, receiver
HMY34_17815	COG5002	protein histidine kinase activity
HMY34_17815	COG2205	protein histidine kinase activity
HMY34_17830	COG0326	Molecular chaperone. Has ATPase activity
HMY34_17850	COG0704	Plays a role in the regulation of phosphate uptake
HMY34_17855	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HMY34_17865	COG0573	inorganic phosphate transmembrane transporter activity
HMY34_17890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HMY34_17920	COG2326	polyphosphate kinase activity
HMY34_17930	COG0737	Belongs to the 5'-nucleotidase family
HMY34_17965	COG0737	Belongs to the 5'-nucleotidase family
HMY34_17975	COG0438	transferase activity, transferring glycosyl groups
HMY34_17985	COG0671	phosphoesterase, PA-phosphatase related
HMY34_17990	COG0438	transferase activity, transferring glycosyl groups
HMY34_17995	COG0745	RESPONSE REGULATOR receiver
HMY34_18005	COG2270	Major facilitator Superfamily
HMY34_18020	COG0697	spore germination
HMY34_18030	COG3012	SEC-C Motif Domain Protein
HMY34_18030	COG3318	Belongs to the UPF0149 family
HMY34_18040	COG2189	Belongs to the N(4) N(6)-methyltransferase family
HMY34_18060	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HMY34_18065	COG3278	Belongs to the heme-copper respiratory oxidase family
HMY34_18080	COG2010	Cytochrome c
HMY34_18085	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HMY34_18090	COG2205	protein histidine kinase activity
HMY34_18090	COG0784	Response regulator, receiver
HMY34_18090	COG5002	protein histidine kinase activity
HMY34_18100	COG1702	phosphate starvation-inducible protein PhoH
HMY34_18105	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HMY34_18110	COG4535	Mg2 and Co2 transporter CorC
HMY34_18115	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HMY34_18120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HMY34_18125	COG4597	amino acid ABC transporter
HMY34_18140	COG0765	amino acid transport
HMY34_18145	COG1126	abc transporter atp-binding protein
HMY34_18185	COG3079	Belongs to the UPF0149 family
HMY34_18190	COG0006	proline dipeptidase activity
HMY34_18210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HMY34_18220	COG0741	lytic transglycosylase activity
HMY34_18220	COG1196	nuclear chromosome segregation
HMY34_18220	COG0739	heme binding
HMY34_18235	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
HMY34_18255	COG1295	ribonuclease BN
HMY34_18260	COG0232	Belongs to the dGTPase family. Type 2 subfamily
HMY34_18290	COG0515	serine threonine protein kinase
HMY34_18290	COG2815	serine threonine protein kinase
HMY34_18295	COG0360	Binds together with S18 to 16S ribosomal RNA
HMY34_18300	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HMY34_18305	COG0359	binds to the 23S rRNA
HMY34_18310	COG0305	Participates in initiation and elongation during chromosome replication
HMY34_18325	COG2205	protein histidine kinase activity
HMY34_18330	COG0745	RESPONSE REGULATOR receiver
HMY34_18350	COG0668	transmembrane transport
HMY34_18370	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HMY34_18380	COG1487	ribonuclease activity
HMY34_18410	COG0330	HflC and HflK could
HMY34_18415	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HMY34_18420	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HMY34_18435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HMY34_18450	COG0243	molybdopterin cofactor binding
HMY34_18470	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HMY34_18475	COG2267	carboxylic ester hydrolase activity
HMY34_18490	COG0723	plastoquinol--plastocyanin reductase activity
HMY34_18510	COG0446	pyridine nucleotide-disulphide oxidoreductase
HMY34_18550	COG0454	-acetyltransferase
HMY34_18565	COG3954	Phosphoribulokinase
HMY34_18580	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HMY34_18585	COG1970	mechanosensitive ion channel activity
HMY34_18590	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HMY34_18610	COG1959	2 iron, 2 sulfur cluster binding
HMY34_18615	COG0271	Belongs to the BolA IbaG family
HMY34_18620	COG0714	Associated with various cellular activities
HMY34_18655	COG0210	DNA helicase
HMY34_18675	COG3023	N-Acetylmuramoyl-L-alanine amidase
HMY34_18685	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HMY34_18690	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HMY34_18695	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HMY34_18695	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HMY34_18710	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HMY34_18715	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HMY34_18730	COG0717	Belongs to the dCTP deaminase family
HMY34_18730	COG0717	Belongs to the dCTP deaminase family
HMY34_18750	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HMY34_18755	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HMY34_18760	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HMY34_18775	COG0330	HflC and HflK could
HMY34_18810	COG0436	Aminotransferase
HMY34_18820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HMY34_18830	COG0386	Belongs to the glutathione peroxidase family
HMY34_18840	COG0497	DNA recombination
HMY34_18845	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HMY34_18850	COG1420	regulation of RNA biosynthetic process
HMY34_18855	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HMY34_18860	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HMY34_18865	COG0363	glucosamine-6-phosphate deaminase activity
HMY34_18880	COG1388	LysM domain
HMY34_18880	COG3942	CHAP domain
HMY34_18895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HMY34_18905	COG0424	maF-like protein
HMY34_18920	COG0416	fatty acid biosynthetic process
HMY34_18925	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HMY34_18930	COG2954	triphosphatase activity
HMY34_18935	COG0513	Belongs to the DEAD box helicase family
HMY34_18955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HMY34_18960	COG0287	Prephenate dehydrogenase
HMY34_18965	COG1073	alpha beta
HMY34_18970	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HMY34_18975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HMY34_18985	COG0776	regulation of translation
HMY34_18990	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
HMY34_18995	COG0284	orotidine-5'-phosphate decarboxylase activity
HMY34_19000	COG2915	High frequency lysogenization protein hflD homolog
HMY34_19005	COG0482	sulfurtransferase activity
HMY34_19030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HMY34_19055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HMY34_19075	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
HMY34_19095	COG2974	May be involved in recombination
HMY34_19105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMY34_19105	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HMY34_19125	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
HMY34_19125	COG3266	domain, Protein
HMY34_19125	COG4932	domain protein
HMY34_19140	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HMY34_19160	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HMY34_19175	COG0439	Biotin carboxylase
HMY34_19180	COG0511	ligase activity, forming carbon-carbon bonds
HMY34_19190	COG0433	COG0433 Predicted ATPase
HMY34_19210	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HMY34_19215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HMY34_19220	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
HMY34_19230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HMY34_19235	COG1393	Belongs to the ArsC family
HMY34_19245	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HMY34_19245	COG1648	precorrin-2 dehydrogenase activity
HMY34_19265	COG0343	queuine tRNA-ribosyltransferase activity
HMY34_19285	COG0129	dihydroxy-acid dehydratase activity
HMY34_19290	COG0800	Aldolase
HMY34_19305	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HMY34_19310	COG0134	indole-3-glycerol-phosphate synthase activity
HMY34_19315	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HMY34_19320	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
HMY34_19325	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
HMY34_19330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HMY34_19335	COG0601	transmembrane transport
HMY34_19340	COG0640	Transcriptional regulator
HMY34_19345	COG1266	CAAX protease self-immunity
HMY34_19350	COG1797	cobyrinic acid a,c-diamide synthase activity
HMY34_19355	COG0316	Belongs to the HesB IscA family
HMY34_19360	COG3850	Histidine kinase
HMY34_19365	COG2197	response regulator
HMY34_19370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HMY34_19370	COG0425	Belongs to the sulfur carrier protein TusA family
HMY34_19380	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HMY34_19385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HMY34_19395	COG0179	Fumarylacetoacetate (FAA) hydrolase
HMY34_19400	COG2862	Uncharacterized protein family, UPF0114
HMY34_19425	COG1002	Type II restriction enzyme, methylase subunits
HMY34_19445	COG1061	Type III restriction enzyme res subunit
HMY34_19470	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HMY34_19485	COG2226	methyltransferase
HMY34_19490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HMY34_19495	COG4452	Inner membrane protein CreD
HMY34_19505	COG2766	serine protein kinase
HMY34_19510	COG2718	Belongs to the UPF0229 family
HMY34_19515	COG2719	SpoVR family
HMY34_19520	COG4566	intracellular signal transduction
HMY34_19550	COG2183	response to ionizing radiation
HMY34_19560	COG0495	leucyl-tRNA aminoacylation
HMY34_19570	COG2084	Dehydrogenase
HMY34_19575	COG0116	Belongs to the methyltransferase superfamily
HMY34_19575	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
HMY34_19590	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HMY34_19600	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HMY34_19610	COG0300	oxidoreductase activity
HMY34_19695	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HMY34_19700	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HMY34_19710	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HMY34_19715	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HMY34_19720	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HMY34_19740	COG0542	response to heat
HMY34_19745	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HMY34_19815	COG1192	Involved in chromosome partitioning
HMY34_20010	COG2356	endonuclease I