locus-tag	class	description
J9260_00050	COG4974	Belongs to the 'phage' integrase family
J9260_00055	COG0517	IMP dehydrogenase activity
J9260_00085	COG0776	regulation of translation
J9260_00095	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
J9260_00095	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J9260_00100	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
J9260_00105	COG0792	nuclease activity
J9260_00110	COG3107	peptidoglycan biosynthetic process
J9260_00130	COG0768	penicillin binding
J9260_00135	COG0772	Belongs to the SEDS family
J9260_00140	COG2951	lytic endotransglycosylase activity
J9260_00150	COG1686	Belongs to the peptidase S11 family
J9260_00155	COG2921	Belongs to the UPF0250 family
J9260_00160	COG0321	lipoyl(octanoyl) transferase activity
J9260_00165	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
J9260_00170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J9260_00175	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
J9260_00180	COG1333	cytochrome c biogenesis protein
J9260_00190	COG0218	Necessary for normal cell division and for the maintenance of normal septation
J9260_00200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J9260_00205	COG1561	YicC-like family, N-terminal region
J9260_00210	COG1040	competence protein
J9260_00275	COG1477	protein flavinylation
J9260_00290	COG0791	NLP P60 protein
J9260_00295	COG2204	response regulator
J9260_00300	COG1940	carbohydrate kinase activity
J9260_00315	COG0625	glutathione transferase activity
J9260_00320	COG4636	protein conserved in cyanobacteria
J9260_00330	COG0537	adenosine 5'-monophosphoramidase activity
J9260_00335	COG1074	ATP-dependent DNA helicase activity
J9260_00360	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
J9260_00365	COG5002	protein histidine kinase activity
J9260_00365	COG5000	phosphorelay sensor kinase activity
J9260_00380	COG0523	cobalamin synthesis protein
J9260_00390	COG4181	ATPase activity
J9260_00395	COG2002	toxin-antitoxin pair type II binding
J9260_00420	COG0741	lytic transglycosylase activity
J9260_00420	COG0739	heme binding
J9260_00420	COG1196	nuclear chromosome segregation
J9260_00430	COG0745	RESPONSE REGULATOR receiver
J9260_00465	COG3609	addiction module antidote protein, CC2985 family
J9260_00475	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J9260_00485	COG4657	Part of a membrane complex involved in electron transport
J9260_00490	COG4660	Part of a membrane complex involved in electron transport
J9260_00495	COG4659	FMN binding
J9260_00500	COG4658	electron transport chain
J9260_00505	COG4656	Part of a membrane complex involved in electron transport
J9260_00510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J9260_00510	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
J9260_00510	COG1013	pyruvate-flavodoxin oxidoreductase activity
J9260_00510	COG0674	pyruvate-flavodoxin oxidoreductase activity
J9260_00515	COG1148	4fe-4S ferredoxin, iron-sulfur binding domain protein
J9260_00515	COG2878	Part of a membrane complex involved in electron transport
J9260_00520	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J9260_00580	COG0277	FAD linked oxidase domain protein
J9260_00585	COG1620	l-lactate permease
J9260_00595	COG2186	Transcriptional regulator
J9260_00600	COG0247	lactate metabolic process
J9260_00605	COG1139	Iron-sulfur cluster binding protein
J9260_00615	COG4999	Histidine kinase
J9260_00615	COG2205	protein histidine kinase activity
J9260_00615	COG3437	response regulator, receiver
J9260_00615	COG3850	Histidine kinase
J9260_00625	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
J9260_00655	COG1217	gtp-binding protein TYPA
J9260_00660	COG2813	Specifically methylates the guanine in position
J9260_00670	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J9260_00675	COG5002	protein histidine kinase activity
J9260_00675	COG0784	Response regulator, receiver
J9260_00675	COG2205	protein histidine kinase activity
J9260_00680	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J9260_00685	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
J9260_00695	COG3031	protein transport across the cell outer membrane
J9260_00715	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J9260_00725	COG0633	Ferredoxin
J9260_00725	COG3217	Mosc domain protein beta barrel domain protein
J9260_00730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J9260_00800	COG0697	spore germination
J9260_00805	COG3609	addiction module antidote protein, CC2985 family
J9260_00825	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
J9260_00865	COG2197	response regulator
J9260_00870	COG4585	Histidine kinase
J9260_00970	COG3738	Protein conserved in bacteria
J9260_01025	COG1403	HNH endonuclease
J9260_01090	COG1487	ribonuclease activity
J9260_01120	COG0642	Histidine kinase
J9260_01125	COG0745	RESPONSE REGULATOR receiver
J9260_01165	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J9260_01175	COG0583	DNA-binding transcription factor activity
J9260_01200	COG4636	protein conserved in cyanobacteria
J9260_01205	COG1643	Atp-dependent helicase
J9260_01215	COG2255	four-way junction helicase activity
J9260_01220	COG0824	Thioesterase
J9260_01225	COG0811	peptide transport
J9260_01240	COG0823	Involved in the tonB-independent uptake of proteins
J9260_01245	COG2885	chlorophyll binding
J9260_01255	COG0602	queuosine metabolic process
J9260_01270	COG4636	protein conserved in cyanobacteria
J9260_01285	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J9260_01290	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J9260_01295	COG1671	Belongs to the UPF0178 family
J9260_01305	COG0210	DNA helicase
J9260_01330	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
J9260_01335	COG0583	DNA-binding transcription factor activity
J9260_01350	COG0009	L-threonylcarbamoyladenylate synthase
J9260_01355	COG1850	ribulose-bisphosphate carboxylase activity
J9260_01385	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
J9260_01390	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
J9260_01420	COG1011	Hydrolase
J9260_01425	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
J9260_01435	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
J9260_01440	COG1194	a g-specific adenine glycosylase
J9260_01460	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
J9260_01465	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
J9260_01470	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
J9260_01475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J9260_01480	COG0659	secondary active sulfate transmembrane transporter activity
J9260_01490	COG0315	cyclic pyranopterin monophosphate synthase activity
J9260_01495	COG0793	Belongs to the peptidase S41A family
J9260_01510	COG1054	Belongs to the UPF0176 family
J9260_01520	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
J9260_01525	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
J9260_01530	COG0189	ligase activity
J9260_01540	COG1765	OsmC-like protein
J9260_01545	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
J9260_01550	COG0791	NLP P60 protein
J9260_01560	COG1592	Rubrerythrin
J9260_01575	COG0142	geranyltranstransferase activity
J9260_01580	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J9260_01585	COG0211	Belongs to the bacterial ribosomal protein bL27 family
J9260_01600	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
J9260_01605	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
J9260_01610	COG2967	ApaG domain
J9260_01615	COG0741	lytic transglycosylase activity
J9260_01665	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J9260_01670	COG1923	regulation of RNA biosynthetic process
J9260_01675	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
J9260_01680	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J9260_01685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J9260_01690	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J9260_01700	COG0165	Argininosuccinate lyase
J9260_01705	COG3275	phosphorelay sensor kinase activity
J9260_01725	COG0356	it plays a direct role in the translocation of protons across the membrane
J9260_01730	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J9260_01735	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J9260_01740	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
J9260_01745	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J9260_01750	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J9260_01755	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J9260_01760	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J9260_01770	COG3028	Belongs to the UPF0307 family
J9260_01775	COG0714	Associated with various cellular activities
J9260_01820	COG0811	peptide transport
J9260_01825	COG0848	biopolymer transport protein
J9260_01830	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
J9260_01835	COG2046	Belongs to the sulfate adenylyltransferase family
J9260_01840	COG0583	DNA-binding transcription factor activity
J9260_01855	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J9260_01860	COG0606	chelatase, subunit chli
J9260_01870	COG0004	ammonium transporteR
J9260_01885	COG2960	long-chain fatty acid transporting porin activity
J9260_01900	COG0762	integral membrane protein
J9260_01905	COG1872	DUF167
J9260_01910	COG0724	RNA recognition motif
J9260_01915	COG2918	glutathione biosynthetic process
J9260_01920	COG0084	hydrolase, TatD family'
J9260_01925	COG2226	methyltransferase
J9260_01930	COG3876	Protein conserved in bacteria
J9260_01940	COG0019	diaminopimelate decarboxylase activity
J9260_01950	COG4636	protein conserved in cyanobacteria
J9260_01960	COG0446	pyridine nucleotide-disulphide oxidoreductase
J9260_01965	COG0617	tRNA 3'-terminal CCA addition
J9260_01980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9260_01990	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J9260_02005	COG0367	asparagine synthase
J9260_02025	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J9260_02030	COG2161	toxin-antitoxin pair type II binding
J9260_02035	COG4115	mRNA cleavage
J9260_02050	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J9260_02055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J9260_02060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
J9260_02065	COG0708	Exodeoxyribonuclease III
J9260_02070	COG2211	Major facilitator Superfamily
J9260_02085	COG0795	lipopolysaccharide-transporting ATPase activity
J9260_02095	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J9260_02120	COG3122	Protein conserved in bacteria
J9260_02125	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J9260_02150	COG2885	chlorophyll binding
J9260_02155	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J9260_02170	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J9260_02180	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
J9260_02220	COG2208	phosphoserine phosphatase activity
J9260_02225	COG5002	protein histidine kinase activity
J9260_02225	COG2205	protein histidine kinase activity
J9260_02225	COG0784	Response regulator, receiver
J9260_02240	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J9260_02250	COG3250	beta-galactosidase activity
J9260_02255	COG1215	transferase activity, transferring glycosyl groups
J9260_02325	COG0745	RESPONSE REGULATOR receiver
J9260_02330	COG2205	protein histidine kinase activity
J9260_02345	COG0305	Participates in initiation and elongation during chromosome replication
J9260_02350	COG0359	binds to the 23S rRNA
J9260_02360	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
J9260_02365	COG0360	Binds together with S18 to 16S ribosomal RNA
J9260_02390	COG1757	Na H antiporter
J9260_02395	COG1757	Na H antiporter
J9260_02405	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
J9260_02420	COG2001	Belongs to the MraZ family
J9260_02425	COG0275	rRNA processing
J9260_02440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J9260_02445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J9260_02450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J9260_02455	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
J9260_02460	COG0772	Belongs to the SEDS family
J9260_02465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
J9260_02470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J9260_02475	COG1181	Belongs to the D-alanine--D-alanine ligase family
J9260_02480	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J9260_02490	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J9260_02495	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
J9260_02505	COG0741	lytic transglycosylase activity
J9260_02505	COG0739	heme binding
J9260_02505	COG1196	nuclear chromosome segregation
J9260_02510	COG0653	protein targeting
J9260_02515	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J9260_02520	COG0494	nUDIX hydrolase
J9260_02530	COG0513	Belongs to the DEAD box helicase family
J9260_02540	COG4536	flavin adenine dinucleotide binding
J9260_02550	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J9260_02575	COG3738	Protein conserved in bacteria
J9260_02580	COG0228	four-way junction DNA binding
J9260_02585	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J9260_02590	COG0336	Belongs to the RNA methyltransferase TrmD family
J9260_02595	COG0335	large ribosomal subunit rRNA binding
J9260_02600	COG5002	protein histidine kinase activity
J9260_02600	COG5001	Diguanylate cyclase
J9260_02605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J9260_02615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J9260_02645	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
J9260_02680	COG0745	RESPONSE REGULATOR receiver
J9260_02685	COG0784	Response regulator, receiver
J9260_02685	COG2205	protein histidine kinase activity
J9260_02700	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
J9260_02720	COG2814	Major facilitator Superfamily
J9260_02725	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
J9260_02725	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
J9260_02730	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
J9260_02745	COG0308	aminopeptidase N
J9260_02765	COG3128	pkhd-type hydroxylase
J9260_02800	COG2221	Nitrite and sulphite reductase 4Fe-4S
J9260_02805	COG2221	Nitrite and sulphite reductase 4Fe-4S
J9260_02810	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J9260_02815	COG2923	Belongs to the DsrF TusC family
J9260_02820	COG2168	tRNA wobble position uridine thiolation
J9260_02825	COG2920	part of a sulfur-relay system
J9260_02840	COG0493	'glutamate synthase
J9260_02885	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J9260_02890	COG4660	Part of a membrane complex involved in electron transport
J9260_02895	COG4659	FMN binding
J9260_02900	COG4658	electron transport chain
J9260_02905	COG4656	Part of a membrane complex involved in electron transport
J9260_02910	COG2878	Part of a membrane complex involved in electron transport
J9260_02915	COG4657	Part of a membrane complex involved in electron transport
J9260_02925	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J9260_02930	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
J9260_02940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J9260_02945	COG1393	Belongs to the ArsC family
J9260_02955	COG1648	precorrin-2 dehydrogenase activity
J9260_02955	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J9260_02985	COG0747	negative chemotaxis
J9260_02990	COG4174	ABC transporter (Permease)
J9260_02995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J9260_03005	COG2177	Part of the ABC transporter FtsEX involved in
J9260_03010	COG2884	Cell division ATP-binding protein ftsE
J9260_03015	COG0552	protein localization to endoplasmic reticulum
J9260_03020	COG0612	Peptidase, M16
J9260_03025	COG0612	Peptidase, M16
J9260_03030	COG0742	ribosomal rna small subunit methyltransferase
J9260_03040	COG1404	Belongs to the peptidase S8 family
J9260_03045	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
J9260_03065	COG0745	RESPONSE REGULATOR receiver
J9260_03070	COG2205	protein histidine kinase activity
J9260_03075	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J9260_03095	COG0640	Transcriptional regulator
J9260_03100	COG0477	Major facilitator Superfamily
J9260_03105	COG0727	PFAM Uncharacterised protein family (UPF0153)
J9260_03110	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J9260_03115	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J9260_03125	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J9260_03130	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J9260_03150	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J9260_03155	COG1459	type II secretion system
J9260_03205	COG1238	metal cluster binding
J9260_03265	COG0583	DNA-binding transcription factor activity
J9260_03270	COG1250	3-hydroxyacyl-CoA dehydrogenase
J9260_03270	COG1024	Enoyl-CoA hydratase
J9260_03275	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J9260_03330	COG0297	glycogen (starch) synthase activity
J9260_03335	COG3118	belongs to the thioredoxin family
J9260_03380	COG3038	cytochrome b561
J9260_03390	COG2194	sulfuric ester hydrolase activity
J9260_03405	COG0446	pyridine nucleotide-disulphide oxidoreductase
J9260_03420	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
J9260_03430	COG0642	Histidine kinase
J9260_03440	COG0446	pyridine nucleotide-disulphide oxidoreductase
J9260_03460	COG0300	oxidoreductase activity
J9260_03475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J9260_03480	COG0791	NLP P60 protein
J9260_03480	COG3103	Sh3 type 3 domain protein
J9260_03480	COG1388	LysM domain
J9260_03490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J9260_03505	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J9260_03520	COG2885	chlorophyll binding
J9260_03535	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J9260_03540	COG0546	phosphoglycolate phosphatase activity
J9260_03585	COG4181	ATPase activity
J9260_03590	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J9260_03600	COG2814	Major facilitator Superfamily
J9260_03610	COG4636	protein conserved in cyanobacteria
J9260_03625	COG0489	protein tyrosine kinase activity
J9260_03630	COG0842	Transport permease protein
J9260_03635	COG1131	(ABC) transporter
J9260_03640	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J9260_03670	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
J9260_03675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J9260_03680	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J9260_03690	COG0149	triose-phosphate isomerase activity
J9260_03705	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J9260_03710	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J9260_03715	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J9260_03720	COG0649	NAD binding
J9260_03735	COG1034	ATP synthesis coupled electron transport
J9260_03740	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
J9260_03745	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J9260_03755	COG0713	ATP synthesis coupled electron transport
J9260_03770	COG1007	ATP synthesis coupled electron transport
J9260_03785	COG0779	Required for maturation of 30S ribosomal subunits
J9260_03790	COG0195	Participates in both transcription termination and antitermination
J9260_03790	COG2251	uridine kinase activity
J9260_03795	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
J9260_03800	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
J9260_03805	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J9260_03815	COG0598	Magnesium transport protein CorA
J9260_03830	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J9260_03860	COG0567	Dehydrogenase, E1 component
J9260_03865	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J9260_03900	COG0372	Belongs to the citrate synthase family
J9260_03930	COG0215	cysteine-tRNA ligase activity
J9260_03945	COG1002	Type II restriction enzyme, methylase subunits
J9260_03965	COG0047	phosphoribosylformylglycinamidine synthase activity
J9260_03965	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J9260_03970	COG1392	Phosphate transport regulator
J9260_03975	COG0306	phosphate transporter
J9260_03980	COG0784	Response regulator, receiver
J9260_03980	COG5002	protein histidine kinase activity
J9260_03980	COG2205	protein histidine kinase activity
J9260_04000	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J9260_04010	COG0573	inorganic phosphate transmembrane transporter activity
J9260_04045	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J9260_04050	COG0469	pyruvate kinase activity
J9260_04080	COG0438	transferase activity, transferring glycosyl groups
J9260_04090	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
J9260_04100	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
J9260_04105	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
J9260_04115	COG0583	DNA-binding transcription factor activity
J9260_04120	COG0438	transferase activity, transferring glycosyl groups
J9260_04125	COG3278	Belongs to the heme-copper respiratory oxidase family
J9260_04140	COG2010	Cytochrome c
J9260_04145	COG0348	domain, Protein
J9260_04170	COG1183	phosphatidylcholine synthase activity
J9260_04180	COG4591	ABC-type transport system involved in lipoprotein release permease component
J9260_04185	COG4591	ABC-type transport system involved in lipoprotein release permease component
J9260_04190	COG1136	(ABC) transporter
J9260_04220	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J9260_04230	COG2205	protein histidine kinase activity
J9260_04235	COG2081	HI0933 family
J9260_04240	COG3012	SEC-C Motif Domain Protein
J9260_04245	COG3132	Protein of unknown function, DUF480
J9260_04265	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J9260_04290	COG0330	HflC and HflK could
J9260_04305	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J9260_04315	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J9260_04320	COG0492	ferredoxin-NADP+ reductase activity
J9260_04325	COG1674	ftsk spoiiie
J9260_04330	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J9260_04335	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J9260_04350	COG0513	Belongs to the DEAD box helicase family
J9260_04355	COG4452	Inner membrane protein CreD
J9260_04385	COG4166	transmembrane transport
J9260_04395	COG0601	transmembrane transport
J9260_04400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J9260_04405	COG0525	valine-tRNA ligase activity
J9260_04455	COG4636	protein conserved in cyanobacteria
J9260_04465	COG2264	protein methyltransferase activity
J9260_04470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J9260_04475	COG0508	dehydrogenase complex catalyzes the overall conversion of
J9260_04485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J9260_04495	COG1177	transmembrane transport
J9260_04500	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J9260_04505	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J9260_04510	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
J9260_04520	COG0330	HflC and HflK could
J9260_04525	COG0330	HflC and HflK could
J9260_04530	COG0739	heme binding
J9260_04535	COG0436	Aminotransferase
J9260_04540	COG0322	excinuclease ABC activity
J9260_04580	COG0261	This protein binds to 23S rRNA in the presence of protein L20
J9260_04580	COG3743	rRNA binding
J9260_04585	COG2885	chlorophyll binding
J9260_04590	COG0303	'Molybdopterin
J9260_04595	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J9260_04615	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J9260_04620	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J9260_04625	COG1862	Preprotein translocase
J9260_04630	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J9260_04635	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
J9260_04640	COG3171	Protein conserved in bacteria
J9260_04655	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
J9260_04660	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J9260_04670	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J9260_04700	COG2951	lytic endotransglycosylase activity
J9260_04710	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
J9260_04715	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J9260_04725	COG0723	plastoquinol--plastocyanin reductase activity
J9260_04730	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
J9260_04735	COG2857	Cytochrome c1
J9260_04740	COG0625	glutathione transferase activity
J9260_04745	COG2969	positive regulation of protein catabolic process
J9260_04755	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J9260_04765	COG2766	serine protein kinase
J9260_04770	COG2718	Belongs to the UPF0229 family
J9260_04775	COG2719	SpoVR family
J9260_04790	COG2951	lytic endotransglycosylase activity
J9260_04795	COG0598	Magnesium transport protein CorA
J9260_04800	COG1660	Displays ATPase and GTPase activities
J9260_04805	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
J9260_04820	COG1137	ATPase activity
J9260_04835	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J9260_04840	COG0517	IMP dehydrogenase activity
J9260_04840	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J9260_04855	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
J9260_04860	COG0443	Heat shock 70 kDa protein
J9260_04865	COG0484	heat shock protein binding
J9260_04870	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
J9260_04880	COG2391	methyltransferase activity
J9260_04895	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
J9260_04900	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
J9260_04905	COG1185	polyribonucleotide nucleotidyltransferase activity
J9260_04910	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J9260_04915	COG0024	Methionine aminopeptidase
J9260_04920	COG0052	Belongs to the universal ribosomal protein uS2 family
J9260_04925	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
J9260_04930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
J9260_04935	COG0287	Prephenate dehydrogenase
J9260_04950	COG3328	transposase activity
J9260_04960	COG3328	transposase activity
J9260_04965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J9260_04965	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
J9260_04980	COG3245	cytochrome
J9260_04985	COG0436	Aminotransferase
J9260_04990	COG2171	N-acyltransferase activity
J9260_04995	COG0420	3'-5' exonuclease activity
J9260_05000	COG4717	serine-type aminopeptidase activity
J9260_05005	COG0741	lytic transglycosylase activity
J9260_05015	COG0811	peptide transport
J9260_05020	COG0848	biopolymer transport protein
J9260_05025	COG1132	(ABC) transporter
J9260_05030	COG1663	tetraacyldisaccharide 4'-kinase activity
J9260_05035	COG2835	tetraacyldisaccharide 4'-kinase activity
J9260_05035	COG1663	tetraacyldisaccharide 4'-kinase activity
J9260_05040	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
J9260_05060	COG3328	transposase activity
J9260_05065	COG0778	Nitroreductase
J9260_05070	COG2321	neutral zinc metallopeptidase
J9260_05110	COG0436	Aminotransferase
J9260_05125	COG2885	chlorophyll binding
J9260_05130	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J9260_05135	COG0628	permease
J9260_05155	COG4232	protein-disulfide reductase activity
J9260_05165	COG5002	protein histidine kinase activity
J9260_05165	COG5001	Diguanylate cyclase
J9260_05175	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
J9260_05180	COG0459	protein refolding
J9260_05185	COG4456	Virulence-associated protein
J9260_05205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J9260_05215	COG1294	oxidase, subunit
J9260_05220	COG4890	Cyd operon protein YbgT
J9260_05240	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
J9260_05255	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
J9260_05265	COG1404	Belongs to the peptidase S8 family
J9260_05275	COG0642	Histidine kinase
J9260_05275	COG3850	Histidine kinase
J9260_05280	COG0745	RESPONSE REGULATOR receiver
J9260_05285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J9260_05295	COG1309	transcriptional regulator
J9260_05300	COG0504	CTP synthase activity
J9260_05305	COG2877	3-deoxy-8-phosphooctulonate synthase activity
J9260_05310	COG0148	phosphopyruvate hydratase activity
J9260_05315	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J9260_05320	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
J9260_05325	COG1393	Belongs to the ArsC family
J9260_05340	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
J9260_05400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J9260_05405	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J9260_05415	COG2264	protein methyltransferase activity
J9260_05420	COG0439	Biotin carboxylase
J9260_05425	COG0511	ligase activity, forming carbon-carbon bonds
J9260_05430	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J9260_05435	COG0433	COG0433 Predicted ATPase
J9260_05460	COG1702	phosphate starvation-inducible protein PhoH
J9260_05465	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
J9260_05470	COG4535	Mg2 and Co2 transporter CorC
J9260_05475	COG0815	Transfers the fatty acyl group on membrane lipoproteins
J9260_05490	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
J9260_05495	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
J9260_05505	COG0495	leucyl-tRNA aminoacylation
J9260_05525	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J9260_05545	COG0746	molybdenum cofactor guanylyltransferase activity
J9260_05570	COG3328	transposase activity
J9260_05615	COG0426	domain, Protein
J9260_05620	COG0633	Ferredoxin
J9260_05630	COG1943	Transposase
J9260_05645	COG1959	2 iron, 2 sulfur cluster binding
J9260_05680	COG0488	(ABC) transporter
J9260_05685	COG1643	Atp-dependent helicase
J9260_05705	COG4657	Part of a membrane complex involved in electron transport
J9260_05710	COG2878	Part of a membrane complex involved in electron transport
J9260_05715	COG4656	Part of a membrane complex involved in electron transport
J9260_05720	COG4658	electron transport chain
J9260_05735	COG2914	Belongs to the UPF0125 (RnfH) family
J9260_05740	COG3411	Ferredoxin
J9260_05765	COG4584	PFAM Integrase catalytic
J9260_05770	COG1484	DNA-dependent DNA replication
J9260_05780	COG3660	Nucleoside-diphosphate-sugar epimerase
J9260_05785	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J9260_05835	COG0676	glucose-6-phosphate 1-epimerase activity
J9260_05840	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
J9260_05845	COG4988	ABC transporter
J9260_05870	COG0714	Associated with various cellular activities
J9260_05885	COG1970	mechanosensitive ion channel activity
J9260_05890	COG0582	viral genome integration into host DNA
J9260_05910	COG2894	cell division
J9260_05945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J9260_05985	COG3328	transposase activity
J9260_06010	COG2003	Belongs to the UPF0758 family
J9260_06230	COG0517	IMP dehydrogenase activity
J9260_06230	COG0516	GMP reductase activity
J9260_06235	COG2197	response regulator
J9260_06240	COG3850	Histidine kinase
J9260_06250	COG2223	nitrite transmembrane transporter activity
J9260_06255	COG2920	part of a sulfur-relay system
J9260_06260	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
J9260_06265	COG1140	nitrate reductase beta subunit
J9260_06270	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
J9260_06275	COG2181	nitrate reductase activity
J9260_06280	COG0303	'Molybdopterin
J9260_06285	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J9260_06290	COG0826	peptidase U32
J9260_06300	COG3154	lipid carrier protein
J9260_06305	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J9260_06315	COG1242	4 iron, 4 sulfur cluster binding
J9260_06320	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J9260_06350	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
J9260_06365	COG0515	serine threonine protein kinase
J9260_06365	COG2815	serine threonine protein kinase
J9260_06370	COG2223	nitrite transmembrane transporter activity
J9260_06375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J9260_06385	COG0243	molybdopterin cofactor binding
J9260_06390	COG0437	4 iron, 4 sulfur cluster binding
J9260_06455	COG2346	COG2346, Truncated hemoglobins
J9260_06465	COG1136	(ABC) transporter
J9260_06465	COG0577	efflux transmembrane transporter activity
J9260_06485	COG1309	transcriptional regulator
J9260_06515	COG4771	TonB-dependent receptor
J9260_06530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J9260_06530	COG0519	Catalyzes the synthesis of GMP from XMP
J9260_06540	COG2010	Cytochrome c
J9260_06550	COG1309	transcriptional regulator
J9260_06590	COG2176	DNA-directed DNA polymerase activity
J9260_06600	COG4804	nuclease activity
J9260_06615	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J9260_06620	COG1111	helicase
J9260_06620	COG1205	dead DEAH box helicase
J9260_06670	COG1569	PIN domain
J9260_06675	COG3311	Transcriptional regulator
J9260_06720	COG0070	glutamate synthase
J9260_06720	COG0069	glutamate synthase activity
J9260_06720	COG0067	glutamate synthase
J9260_06725	COG0493	'glutamate synthase
J9260_06770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J9260_06775	COG1573	uracil-dna glycosylase
J9260_06780	COG0456	acetyltransferase
J9260_06790	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J9260_06795	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
J9260_06825	COG0372	Belongs to the citrate synthase family
J9260_06840	COG0505	Belongs to the CarA family
J9260_06850	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J9260_06855	COG0406	alpha-ribazole phosphatase activity
J9260_06865	COG0033	Phosphoglucomutase
J9260_06875	COG1959	2 iron, 2 sulfur cluster binding
J9260_06880	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J9260_06885	COG2363	Small membrane protein
J9260_06895	COG2900	Belongs to the SlyX family
J9260_06900	COG0137	argininosuccinate synthase activity
J9260_06915	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
J9260_06920	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J9260_06925	COG1752	Esterase of the alpha-beta hydrolase superfamily
J9260_06955	COG0789	Transcriptional regulator
J9260_06960	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J9260_06965	COG1136	(ABC) transporter
J9260_06975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J9260_07010	COG3459	Glycosyltransferase 36 associated
J9260_07080	COG4608	Belongs to the ABC transporter superfamily
J9260_07090	COG0519	Catalyzes the synthesis of GMP from XMP
J9260_07130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J9260_07160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J9260_07170	COG0302	gtp cyclohydrolase
J9260_07185	COG0343	queuine tRNA-ribosyltransferase activity
J9260_07190	COG0247	lactate metabolic process
J9260_07195	COG0277	FAD linked oxidase domain protein
J9260_07200	COG0277	FAD linked oxidase domain protein
J9260_07205	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
J9260_07215	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
J9260_07225	COG0291	Belongs to the bacterial ribosomal protein bL35 family
J9260_07230	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
J9260_07235	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
J9260_07240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J9260_07240	COG0072	phenylalanine-tRNA ligase activity
J9260_07245	COG0776	regulation of translation
J9260_07285	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J9260_07290	COG0077	Prephenate dehydratase
J9260_07290	COG1605	Chorismate mutase
J9260_07305	COG3118	belongs to the thioredoxin family
J9260_07310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J9260_07315	COG0825	malonyl-CoA metabolic process
J9260_07320	COG0037	tRNA processing
J9260_07340	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J9260_07360	COG0587	DNA-directed DNA polymerase activity
J9260_07385	COG0517	IMP dehydrogenase activity
J9260_07390	COG4974	Belongs to the 'phage' integrase family
J9260_07395	COG1176	ABC-type spermidine putrescine transport system, permease component I
J9260_07405	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J9260_07415	COG0489	protein tyrosine kinase activity
J9260_07425	COG0717	Belongs to the dCTP deaminase family
J9260_07445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J9260_07455	COG1199	ATP-dependent helicase activity
J9260_07460	COG1214	PFAM Peptidase M22, glycoprotease
J9260_07465	COG1509	lysine 2,3-aminomutase activity
J9260_07510	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J9260_07525	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
J9260_07535	COG0756	dUTP diphosphatase activity
J9260_07540	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J9260_07545	COG2003	Belongs to the UPF0758 family
J9260_07550	COG0277	FAD linked oxidase domain protein
J9260_07565	COG1196	nuclear chromosome segregation
J9260_07570	COG3115	cell septum assembly
J9260_07575	COG3842	ATPase activity
J9260_07580	COG1178	ABC-type Fe3 transport system permease component
J9260_07585	COG1840	ABC-type Fe3 transport system, periplasmic component
J9260_07590	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J9260_07595	COG1555	photosystem II stabilization
J9260_07605	COG0754	glutathionylspermidine amidase activity
J9260_07620	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
J9260_07630	COG0028	Belongs to the TPP enzyme family
J9260_07650	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
J9260_07675	COG3954	Phosphoribulokinase
J9260_07705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J9260_07715	COG0481	GTPase activity
J9260_07720	COG0681	Belongs to the peptidase S26 family
J9260_07735	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J9260_07740	COG1381	Involved in DNA repair and RecF pathway recombination
J9260_07745	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J9260_07750	COG0736	holo-[acyl-carrier-protein] synthase activity
J9260_07795	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J9260_07810	COG5002	protein histidine kinase activity
J9260_07810	COG2205	protein histidine kinase activity
J9260_07810	COG0784	Response regulator, receiver
J9260_07875	COG1858	cytochrome C peroxidase
J9260_07880	COG2205	protein histidine kinase activity
J9260_07885	COG0745	RESPONSE REGULATOR receiver
J9260_07910	COG1566	PFAM secretion protein HlyD family protein
J9260_07915	COG1136	(ABC) transporter
J9260_07915	COG0577	efflux transmembrane transporter activity
J9260_07920	COG0577	efflux transmembrane transporter activity
J9260_07920	COG1136	(ABC) transporter
J9260_07925	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J9260_07930	COG2119	membrane
J9260_07935	COG0116	Belongs to the methyltransferase superfamily
J9260_07935	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J9260_07945	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
J9260_07960	COG0300	oxidoreductase activity
J9260_07980	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
J9260_07985	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J9260_07995	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J9260_08000	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
J9260_08015	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J9260_08020	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
J9260_08025	COG0542	response to heat
J9260_08030	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J9260_08045	COG2915	High frequency lysogenization protein hflD homolog
J9260_08050	COG0284	orotidine-5'-phosphate decarboxylase activity
J9260_08055	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
J9260_08060	COG0776	regulation of translation
J9260_08070	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
J9260_08075	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
J9260_08105	COG0714	Associated with various cellular activities
J9260_08110	COG0271	Belongs to the BolA IbaG family
J9260_08120	COG1136	(ABC) transporter
J9260_08120	COG0577	efflux transmembrane transporter activity
J9260_08125	COG0577	efflux transmembrane transporter activity
J9260_08125	COG1136	(ABC) transporter
J9260_08130	COG0577	efflux transmembrane transporter activity
J9260_08130	COG1136	(ABC) transporter
J9260_08150	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J9260_08165	COG2084	Dehydrogenase
J9260_08170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J9260_08195	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J9260_08200	COG0745	RESPONSE REGULATOR receiver
J9260_08205	COG0438	transferase activity, transferring glycosyl groups
J9260_08220	COG0513	Belongs to the DEAD box helicase family
J9260_08225	COG2954	triphosphatase activity
J9260_08230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J9260_08235	COG0416	fatty acid biosynthetic process
J9260_08240	COG0333	Belongs to the bacterial ribosomal protein bL32 family
J9260_08250	COG0424	maF-like protein
J9260_08265	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
J9260_08290	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J9260_08305	COG1366	Belongs to the anti-sigma-factor antagonist family
J9260_08350	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
J9260_08355	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J9260_08360	COG3123	guanosine phosphorylase activity
J9260_08365	COG0312	modulator of DNA gyrase
J9260_08370	COG0312	modulator of DNA gyrase
J9260_08390	COG0424	maF-like protein
J9260_08395	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
J9260_08405	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J9260_08415	COG1473	amidohydrolase
J9260_08440	COG1674	ftsk spoiiie
J9260_08440	COG0531	amino acid
J9260_08455	COG0444	Belongs to the ABC transporter superfamily
J9260_08460	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
J9260_08465	COG0402	S-adenosylhomocysteine deaminase activity
J9260_08470	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J9260_08485	COG0500	methyltransferase
J9260_08490	COG4106	trans-aconitate 2-methyltransferase activity
J9260_08495	COG1028	Short-chain dehydrogenase reductase Sdr
J9260_08500	COG0326	Molecular chaperone. Has ATPase activity
J9260_08505	COG0646	methionine synthase
J9260_08505	COG1410	methionine synthase
J9260_08555	COG1850	ribulose-bisphosphate carboxylase activity
J9260_08585	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J9260_08590	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J9260_08600	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
J9260_08625	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J9260_08625	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J9260_08630	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J9260_08635	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
J9260_08655	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J9260_08670	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J9260_08675	COG0688	phosphatidylethanolamine metabolic process
J9260_08690	COG1850	ribulose-bisphosphate carboxylase activity
J9260_08710	COG3328	transposase activity
J9260_08735	COG0393	Putative heavy-metal-binding
J9260_08775	COG0404	The glycine cleavage system catalyzes the degradation of glycine
J9260_08805	COG1006	Multisubunit Na H antiporter MnhC subunit
J9260_08810	COG0651	ATP synthesis coupled electron transport
J9260_08820	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J9260_08825	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J9260_08825	COG0649	NAD binding
J9260_08830	COG0649	NAD binding
J9260_08860	COG3008	intermembrane lipid transfer
J9260_08875	COG1858	cytochrome C peroxidase
J9260_08880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J9260_08885	COG3040	lipid binding
J9260_08905	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J9260_08930	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
J9260_08955	COG0105	UTP biosynthetic process
J9260_08960	COG0820	rRNA (adenine-C2-)-methyltransferase activity
J9260_08980	COG0124	histidyl-tRNA synthetase
J9260_08985	COG2976	Protein conserved in bacteria
J9260_08990	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J9260_09005	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J9260_09010	COG0134	indole-3-glycerol-phosphate synthase activity
J9260_09015	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
J9260_09020	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J9260_09025	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
J9260_09100	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J9260_09100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J9260_09110	COG0477	Major facilitator Superfamily
J9260_09115	COG0714	Associated with various cellular activities
J9260_09125	COG2957	Belongs to the agmatine deiminase family
J9260_09140	COG2304	oxidoreductase activity
J9260_09155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J9260_09160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J9260_09165	COG2181	nitrate reductase activity
J9260_09170	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
J9260_09175	COG1140	nitrate reductase beta subunit
J9260_09180	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
J9260_09185	COG2920	part of a sulfur-relay system
J9260_09190	COG2223	nitrite transmembrane transporter activity
J9260_09210	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J9260_09215	COG3850	Histidine kinase
J9260_09220	COG2197	response regulator
J9260_09225	COG0517	IMP dehydrogenase activity
J9260_09230	COG0243	molybdopterin cofactor binding
J9260_09240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J9260_09250	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J9260_09255	COG3328	transposase activity
J9260_09265	COG1238	metal cluster binding
J9260_09270	COG1116	anion transmembrane transporter activity
J9260_09275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J9260_09280	COG1116	anion transmembrane transporter activity
J9260_09280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J9260_09285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J9260_09285	COG1116	anion transmembrane transporter activity
J9260_09320	COG2183	response to ionizing radiation
J9260_09345	COG0557	exoribonuclease II activity
J9260_09350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J9260_09365	COG1322	Protein conserved in bacteria
J9260_09370	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
J9260_09375	COG2894	cell division
J9260_09390	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J9260_09415	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
J9260_09420	COG2944	sequence-specific DNA binding
J9260_09425	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J9260_09445	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J9260_09450	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J9260_09455	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J9260_09460	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J9260_09470	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J9260_09480	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
J9260_09485	COG0575	Belongs to the CDS family
J9260_09490	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J9260_09495	COG0233	cytoplasmic translational termination
J9260_09500	COG0528	UMP kinase activity
J9260_09505	COG3150	esterase
J9260_09510	COG1420	regulation of RNA biosynthetic process
J9260_09515	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J9260_09520	COG0497	DNA recombination
J9260_09535	COG2197	response regulator
J9260_09540	COG3850	Histidine kinase
J9260_09550	COG1797	cobyrinic acid a,c-diamide synthase activity
J9260_09565	COG3328	transposase activity
J9260_09580	COG4974	Belongs to the 'phage' integrase family
J9260_09585	COG0517	IMP dehydrogenase activity
J9260_09625	COG1074	ATP-dependent DNA helicase activity
J9260_09655	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
J9260_09670	COG1472	Belongs to the glycosyl hydrolase 3 family
J9260_09680	COG0167	dihydroorotate dehydrogenase activity
J9260_09695	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J9260_09695	COG4797	methyltransferase
J9260_09705	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
J9260_09755	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J9260_09810	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
J9260_09870	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J9260_09890	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
J9260_09900	COG2863	cytochrome
J9260_09910	COG0446	pyridine nucleotide-disulphide oxidoreductase
J9260_09915	COG2814	Major facilitator Superfamily
J9260_09925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J9260_09950	COG0517	IMP dehydrogenase activity
J9260_09955	COG4974	Belongs to the 'phage' integrase family
J9260_09975	COG0446	pyridine nucleotide-disulphide oxidoreductase
J9260_09995	COG0723	plastoquinol--plastocyanin reductase activity
J9260_10010	COG0450	alkyl hydroperoxide reductase
J9260_10015	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J9260_10030	COG0243	molybdopterin cofactor binding
J9260_10050	COG0442	prolyl-tRNA aminoacylation
J9260_10055	COG0138	bifunctional purine biosynthesis protein purh
J9260_10065	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
J9260_10070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J9260_10075	COG0629	single-stranded DNA binding
J9260_10080	COG2814	Major facilitator Superfamily
J9260_10085	COG3272	Protein of unknown function (DUF1722)
J9260_10090	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
J9260_10090	COG3264	Mechanosensitive ion channel
J9260_10100	COG3657	addiction module killer protein
J9260_10105	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J9260_10110	COG3842	ATPase activity
J9260_10130	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
J9260_10160	COG2957	Belongs to the agmatine deiminase family
J9260_10165	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J9260_10190	COG1132	(ABC) transporter
J9260_10235	COG0500	methyltransferase
J9260_10245	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J9260_10250	COG0280	phosphate acetyltransferase
J9260_10250	COG0857	belongs to the CobB CobQ family
J9260_10255	COG2319	Wd-40 repeat
J9260_10255	COG4249	Peptidase C14 caspase catalytic subunit p20
J9260_10280	COG4115	mRNA cleavage
J9260_10285	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J9260_10285	COG0519	Catalyzes the synthesis of GMP from XMP
J9260_10300	COG1570	exodeoxyribonuclease VII activity
J9260_10325	COG0513	Belongs to the DEAD box helicase family
J9260_10330	COG0386	Belongs to the glutathione peroxidase family
J9260_10355	COG3647	Membrane
J9260_10380	COG2189	Belongs to the N(4) N(6)-methyltransferase family
J9260_10415	COG2308	Evidence 4 Homologs of previously reported genes of
J9260_10425	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J9260_10430	COG0012	GTP binding
J9260_10435	COG0193	aminoacyl-tRNA hydrolase activity
J9260_10440	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
J9260_10460	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
J9260_10465	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
J9260_10475	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
J9260_10480	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
J9260_10485	COG2890	protein-(glutamine-N5) methyltransferase activity
J9260_10525	COG0521	Mo-molybdopterin cofactor biosynthetic process
J9260_10530	COG0501	Belongs to the peptidase M48B family
J9260_10555	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J9260_10570	COG0446	pyridine nucleotide-disulphide oxidoreductase
J9260_10580	COG2863	cytochrome
J9260_10585	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J9260_10590	COG0564	pseudouridine synthase activity
J9260_10595	COG2226	methyltransferase
J9260_10605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J9260_10605	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J9260_10615	COG2974	May be involved in recombination
J9260_10635	COG1959	2 iron, 2 sulfur cluster binding
J9260_10640	COG0583	DNA-binding transcription factor activity
J9260_10655	COG0179	Fumarylacetoacetate (FAA) hydrolase
J9260_10660	COG0583	DNA-binding transcription factor activity
J9260_10670	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J9260_10675	COG3657	addiction module killer protein
J9260_10720	COG0517	IMP dehydrogenase activity
J9260_10725	COG4974	Belongs to the 'phage' integrase family
J9260_10750	COG1295	ribonuclease BN
J9260_10780	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
J9260_10790	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
J9260_10795	COG2137	regulation of response to DNA damage stimulus
J9260_10805	COG3243	poly(R)-hydroxyalkanoic acid synthase
J9260_10815	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J9260_10815	COG0616	signal peptide processing
J9260_10820	COG0546	phosphoglycolate phosphatase activity
J9260_10830	COG1530	ribonuclease E activity
J9260_10835	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J9260_10885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J9260_10905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J9260_10915	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
J9260_10920	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
J9260_10925	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
J9260_10930	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J9260_10955	COG3328	transposase activity
J9260_10975	COG3328	transposase activity
J9260_11000	COG3243	poly(R)-hydroxyalkanoic acid synthase
J9260_11010	COG0183	Belongs to the thiolase family
J9260_11015	COG1028	Short-chain dehydrogenase reductase Sdr
J9260_11020	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
J9260_11025	COG0783	Belongs to the Dps family
J9260_11030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J9260_11045	COG3853	Toxic anion resistance protein (TelA)
J9260_11065	COG2920	part of a sulfur-relay system
J9260_11070	COG0791	NLP P60 protein
J9260_11075	COG1652	LysM domain
J9260_11215	COG3328	transposase activity
J9260_11220	COG3328	transposase activity
J9260_11240	COG0473	3-isopropylmalate dehydrogenase activity
J9260_11245	COG0556	nucleotide-excision repair
J9260_11275	COG0348	domain, Protein
J9260_11280	COG2010	Cytochrome c
J9260_11295	COG3278	Belongs to the heme-copper respiratory oxidase family
J9260_11300	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
J9260_11330	COG2189	Belongs to the N(4) N(6)-methyltransferase family
J9260_11335	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J9260_11340	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J9260_11345	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J9260_11350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J9260_11365	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
J9260_11380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J9260_11390	COG3695	enzyme binding
J9260_11395	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J9260_11400	COG2850	peptidyl-arginine hydroxylation
J9260_11420	COG2373	Large extracellular alpha-helical protein
J9260_11440	COG0517	IMP dehydrogenase activity
J9260_11440	COG0516	GMP reductase activity
J9260_11445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J9260_11450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J9260_11470	COG0789	Transcriptional regulator
J9260_11475	COG0415	Belongs to the DNA photolyase family
J9260_11480	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
J9260_11485	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J9260_11500	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J9260_11510	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
J9260_11530	COG1127	ABC transporter
J9260_11535	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J9260_11560	COG1519	Transferase
J9260_11565	COG0859	PFAM glycosyl transferase family 9
J9260_11570	COG0463	Glycosyl transferase, family 2
J9260_11580	COG0859	PFAM glycosyl transferase family 9
J9260_11600	COG0438	transferase activity, transferring glycosyl groups
J9260_11605	COG0438	transferase activity, transferring glycosyl groups
J9260_11620	COG0667	Aldo Keto reductase
J9260_11630	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J9260_11630	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J9260_11635	COG1560	Kdo2-lipid A biosynthetic process
J9260_11640	COG1047	Peptidyl-prolyl cis-trans
J9260_11645	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
J9260_11680	COG0004	ammonium transporteR
J9260_11695	COG0247	lactate metabolic process
J9260_11705	COG0542	response to heat
J9260_11740	COG2814	Major facilitator Superfamily
J9260_11785	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
J9260_11790	COG0180	Tryptophanyl-tRNA synthetase
J9260_11795	COG1994	Peptidase M50
J9260_11800	COG0009	L-threonylcarbamoyladenylate synthase
J9260_11805	COG2917	probably involved in intracellular septation
J9260_11810	COG2350	Protein conserved in bacteria
J9260_11815	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J9260_11825	COG0436	Aminotransferase
J9260_11835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J9260_11840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J9260_11845	COG1160	GTP binding
J9260_11850	COG0730	response to heat
J9260_11860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J9260_11870	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
J9260_11875	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
J9260_11915	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
J9260_11925	COG0828	Belongs to the bacterial ribosomal protein bS21 family
J9260_11930	COG0735	belongs to the Fur family
J9260_11935	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J9260_11945	COG2914	Belongs to the UPF0125 (RnfH) family
J9260_11950	COG2867	negative regulation of translational initiation
J9260_11970	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J9260_11980	COG0066	3-isopropylmalate dehydratase activity
J9260_11985	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
J9260_11990	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
J9260_11990	COG3266	domain, Protein
J9260_11990	COG4932	domain protein
J9260_12015	COG0204	Acyl-transferase
J9260_12015	COG0318	PFAM AMP-dependent synthetase and ligase
J9260_12040	COG4249	Peptidase C14 caspase catalytic subunit p20
J9260_12040	COG2319	Wd-40 repeat
J9260_12055	COG0328	RNA-DNA hybrid ribonuclease activity
J9260_12065	COG0741	lytic transglycosylase activity
J9260_12065	COG1388	LysM domain
J9260_12075	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J9260_12090	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J9260_12110	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J9260_12115	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J9260_12135	COG0776	regulation of translation
J9260_12140	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
J9260_12145	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
J9260_12150	COG0740	serine-type endopeptidase activity
J9260_12155	COG0544	peptidyl-prolyl cis-trans isomerase activity
J9260_12180	COG0745	RESPONSE REGULATOR receiver
J9260_12195	COG0840	transmembrane signaling receptor activity
J9260_12200	COG0784	Response regulator, receiver
J9260_12200	COG0643	Histidine kinase
J9260_12200	COG2198	Histidine kinase
J9260_12205	COG0745	RESPONSE REGULATOR receiver
J9260_12210	COG1484	DNA-dependent DNA replication
J9260_12215	COG4584	PFAM Integrase catalytic
J9260_12245	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J9260_12250	COG1196	nuclear chromosome segregation
J9260_12250	COG0741	lytic transglycosylase activity
J9260_12250	COG0739	heme binding
J9260_12255	COG2975	iron-sulfur cluster assembly
J9260_12260	COG0633	Ferredoxin
J9260_12265	COG0443	Heat shock 70 kDa protein
J9260_12275	COG0316	Belongs to the HesB IscA family
J9260_12280	COG0822	iron-sulfur transferase activity
J9260_12285	COG1104	cysteine desulfurase activity
J9260_12290	COG1959	2 iron, 2 sulfur cluster binding
J9260_12345	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J9260_12350	COG0537	adenosine 5'-monophosphoramidase activity
J9260_12390	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
J9260_12405	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J9260_12415	COG0579	oxidoreductase
J9260_12420	COG0363	glucosamine-6-phosphate deaminase activity
J9260_12425	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
J9260_12430	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J9260_12440	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
J9260_12520	COG0582	viral genome integration into host DNA
J9260_12525	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J9260_12545	COG3328	transposase activity
J9260_12555	COG1234	tRNA 3'-trailer cleavage
J9260_12585	COG1088	dTDP-glucose 4,6-dehydratase activity
J9260_12590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J9260_12640	COG0489	protein tyrosine kinase activity
J9260_12695	COG3328	transposase activity
J9260_12700	COG0232	Belongs to the dGTPase family. Type 2 subfamily
J9260_12705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J9260_12715	COG0861	Integral membrane protein TerC family
J9260_12720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J9260_12725	COG2270	Major facilitator Superfamily
J9260_12740	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J9260_12760	COG0316	Belongs to the HesB IscA family
J9260_12775	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
J9260_12785	COG1981	membrane
J9260_12790	COG0494	nUDIX hydrolase
J9260_12800	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J9260_12810	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
J9260_12810	COG0662	Cupin 2, conserved barrel domain protein
J9260_12815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J9260_12840	COG0438	transferase activity, transferring glycosyl groups
J9260_12895	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
J9260_12920	COG4636	protein conserved in cyanobacteria
J9260_12925	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J9260_12935	COG0488	(ABC) transporter
J9260_12945	COG2833	Protein of unknown function (DUF455)
J9260_12960	COG2379	hydroxypyruvate reductase
J9260_12970	COG1376	ErfK ybiS ycfS ynhG family protein
J9260_12980	COG1286	toxin biosynthetic process
J9260_12990	COG0285	dihydrofolate synthase activity
J9260_13000	COG0159	tryptophan synthase activity
J9260_13005	COG0133	tryptophan synthase activity
J9260_13030	COG0135	phosphoribosylanthranilate isomerase activity
J9260_13035	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
J9260_13040	COG4804	nuclease activity
J9260_13045	COG0069	glutamate synthase activity
J9260_13055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J9260_13065	COG0006	proline dipeptidase activity
J9260_13095	COG2138	Cobalamin (vitamin B12) biosynthesis CbiX protein
J9260_13105	COG2267	carboxylic ester hydrolase activity
J9260_13110	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
J9260_13115	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
J9260_13135	COG1187	pseudouridine synthase activity
J9260_13155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
J9260_13160	COG1115	amino acid carrier protein
J9260_13170	COG3243	poly(R)-hydroxyalkanoic acid synthase
J9260_13180	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J9260_13185	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
J9260_13195	COG1215	transferase activity, transferring glycosyl groups
J9260_13210	COG1215	transferase activity, transferring glycosyl groups
J9260_13215	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J9260_13250	COG1450	Type ii and iii secretion system protein
J9260_13265	COG3166	PFAM Fimbrial assembly family protein
J9260_13275	COG0582	viral genome integration into host DNA
J9260_13305	COG0740	serine-type endopeptidase activity
J9260_13385	COG4983	Phage plasmid primase, P4 family domain protein
J9260_13410	COG0018	arginyl-trna synthetase
J9260_13430	COG1193	negative regulation of DNA recombination
J9260_13435	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J9260_13440	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J9260_13445	COG1388	LysM domain
J9260_13445	COG4942	peptidase
J9260_13475	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
J9260_13480	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
J9260_13510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J9260_13515	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J9260_13520	COG0142	geranyltranstransferase activity
J9260_13525	COG1722	exodeoxyribonuclease VII activity
J9260_13535	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
J9260_13540	COG0237	dephospho-CoA kinase activity
J9260_13545	COG0268	Binds directly to 16S ribosomal RNA
J9260_13550	COG1475	DNA binding
J9260_13555	COG1192	Involved in chromosome partitioning
J9260_13560	COG0357	Ribosomal RNA small subunit methyltransferase G
J9260_13565	COG0445	tRNA wobble uridine modification
J9260_13570	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
J9260_13580	COG0203	ribosomal protein L17
J9260_13585	COG0202	RNA polymerase activity
J9260_13590	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
J9260_13595	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
J9260_13600	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
J9260_13605	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J9260_13610	COG0201	protein transport
J9260_13615	COG0200	Binds to the 23S rRNA
J9260_13620	COG1841	ribosomal large subunit assembly
J9260_13630	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
J9260_13635	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
J9260_13640	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
J9260_13645	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J9260_13650	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
J9260_13655	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
J9260_13660	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
J9260_13665	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
J9260_13670	COG0255	Belongs to the universal ribosomal protein uL29 family
J9260_13675	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
J9260_13680	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
J9260_13685	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
J9260_13690	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
J9260_13700	COG0089	rRNA binding
J9260_13705	COG0088	Forms part of the polypeptide exit tunnel
J9260_13710	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
J9260_13715	COG0051	transcription antitermination factor activity, RNA binding
J9260_13725	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J9260_13730	COG0049	tRNA binding
J9260_13735	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
J9260_13745	COG0085	RNA polymerase activity
J9260_13750	COG0222	ribosome binding
J9260_13755	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
J9260_13760	COG0081	regulation of translation
J9260_13775	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J9260_13805	COG2911	Protein conserved in bacteria
J9260_13810	COG0729	surface antigen
J9260_13815	COG2027	D-alanyl-D-alanine carboxypeptidase
J9260_13820	COG1720	tRNA m6t6A37 methyltransferase activity
J9260_13840	COG1434	Gram-negative-bacterium-type cell wall biogenesis
J9260_13845	COG0748	coenzyme F420 binding
J9260_13855	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J9260_13860	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
J9260_13865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J9260_13870	COG1121	(ABC) transporter
J9260_13875	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
J9260_13925	COG1805	sodium ion transport
J9260_13940	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
J9260_13945	COG2871	sodium ion transport
J9260_13955	COG0617	tRNA 3'-terminal CCA addition
J9260_13955	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
J9260_13955	COG0517	IMP dehydrogenase activity
J9260_13965	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
J9260_13975	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J9260_14035	COG1518	maintenance of DNA repeat elements
J9260_14045	COG1484	DNA-dependent DNA replication
J9260_14050	COG4584	PFAM Integrase catalytic
J9260_14200	COG1090	epimerase
J9260_14225	COG1131	(ABC) transporter
J9260_14235	COG1028	Short-chain dehydrogenase reductase Sdr
J9260_14245	COG1968	undecaprenyl-diphosphatase activity
J9260_14255	COG1444	tRNA N-acetyltransferase activity
J9260_14265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J9260_14265	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J9260_14285	COG0488	(ABC) transporter
J9260_14290	COG0745	RESPONSE REGULATOR receiver
J9260_14310	COG2022	thiamine diphosphate biosynthetic process
J9260_14315	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J9260_14335	COG1301	dicarboxylic acid transport
J9260_14340	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J9260_14345	COG1509	lysine 2,3-aminomutase activity
J9260_14360	COG0659	secondary active sulfate transmembrane transporter activity
J9260_14385	COG0741	lytic transglycosylase activity
J9260_14400	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J9260_14410	COG1944	ATP diphosphatase activity
J9260_14415	COG3338	carbonate dehydratase activity
J9260_14430	COG1403	HNH endonuclease
J9260_14455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J9260_14465	COG0488	(ABC) transporter
J9260_14475	COG0301	tRNA thio-modification
J9260_14480	COG2268	Band 7 protein
J9260_14495	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J9260_14500	COG0131	Imidazoleglycerol-phosphate dehydratase
J9260_14505	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
J9260_14510	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J9260_14520	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J9260_14525	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J9260_14535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J9260_14540	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
J9260_14545	COG0352	thiamine-phosphate diphosphorylase activity
J9260_14555	COG1042	CoA-binding domain protein
J9260_14555	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J9260_14555	COG0045	succinate-CoA ligase (ADP-forming) activity
J9260_14560	COG0123	including yeast histone deacetylase and acetoin utilization protein
J9260_14585	COG0513	Belongs to the DEAD box helicase family
J9260_14590	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J9260_14605	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J9260_14610	COG2204	response regulator
J9260_14615	COG3852	Histidine kinase
J9260_14635	COG0243	molybdopterin cofactor binding
J9260_14640	COG0437	4 iron, 4 sulfur cluster binding
J9260_14660	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J9260_14675	COG3956	TIGRFAM MazG family protein
J9260_14680	COG0632	four-way junction helicase activity
J9260_14690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J9260_14700	COG0751	glycine-tRNA ligase activity
J9260_14710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J9260_14760	COG0735	belongs to the Fur family
J9260_14765	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
J9260_14770	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
J9260_14795	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J9260_14800	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
J9260_14820	COG0356	it plays a direct role in the translocation of protons across the membrane
J9260_14830	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
J9260_14835	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
J9260_14840	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
J9260_14850	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
J9260_14865	COG0543	2 iron, 2 sulfur cluster binding
J9260_14865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J9260_14880	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
J9260_14895	COG4783	chaperone-mediated protein folding
J9260_14900	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
J9260_14905	COG2210	Belongs to the sulfur carrier protein TusA family
J9260_14915	COG1408	metallophosphoesterase
J9260_14935	COG0840	transmembrane signaling receptor activity
J9260_14945	COG0784	Response regulator, receiver
J9260_14945	COG2198	Histidine kinase
J9260_14945	COG0643	Histidine kinase
J9260_14970	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J9260_14975	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
J9260_14980	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J9260_14990	COG4452	Inner membrane protein CreD
J9260_14995	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J9260_15020	COG4650	regulator
J9260_15035	COG3001	Fructosamine kinase
J9260_15040	COG1690	Belongs to the RtcB family
J9260_15065	COG3550	peptidyl-serine autophosphorylation
J9260_15080	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J9260_15085	COG4628	conserved protein (DUF2132)
J9260_15110	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
J9260_15135	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
J9260_15145	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
J9260_15150	COG0604	alcohol dehydrogenase
J9260_15195	COG1902	pentaerythritol trinitrate reductase activity
J9260_15205	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J9260_15215	COG3002	Belongs to the UPF0753 family
J9260_15220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J9260_15225	COG3002	Belongs to the UPF0753 family
J9260_15245	COG0596	Alpha beta hydrolase
J9260_15250	COG1490	D-aminoacyl-tRNA deacylase activity
J9260_15270	COG5007	Belongs to the BolA IbaG family
J9260_15275	COG1611	Belongs to the LOG family
J9260_15285	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J9260_15300	COG0174	glutamine synthetase
J9260_15335	COG3852	Histidine kinase
J9260_15345	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J9260_15375	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J9260_15380	COG0375	protein maturation
J9260_15420	COG0542	response to heat
J9260_15460	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
J9260_15475	COG0732	type I restriction modification DNA specificity domain
J9260_15485	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
J9260_15505	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
J9260_15545	COG2204	response regulator
J9260_15560	COG3852	Histidine kinase
J9260_15610	COG2824	Alkylphosphonate utilization operon protein PhnA
J9260_15630	COG3657	addiction module killer protein
J9260_15720	COG4983	Phage plasmid primase, P4 family domain protein
J9260_15765	COG0784	Response regulator, receiver
J9260_15765	COG3437	response regulator, receiver
J9260_15775	COG4206	TonB-dependent receptor
J9260_15780	COG0181	hydroxymethylbilane synthase activity
J9260_15785	COG1587	Uroporphyrinogen-III synthase
J9260_15800	COG0281	malic enzyme
J9260_15805	COG4783	chaperone-mediated protein folding
J9260_15810	COG0254	rRNA binding
J9260_15820	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
J9260_15825	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J9260_15830	COG3411	Ferredoxin
J9260_15875	COG0840	transmembrane signaling receptor activity
J9260_15890	COG2885	chlorophyll binding
J9260_15905	COG0084	hydrolase, TatD family'
J9260_15920	COG0259	pyridoxamine-phosphate oxidase activity
J9260_15935	COG0488	(ABC) transporter
J9260_15940	COG2002	toxin-antitoxin pair type II binding
J9260_15950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
J9260_15965	COG0243	molybdopterin cofactor binding
J9260_15970	COG0437	4 iron, 4 sulfur cluster binding
J9260_15975	COG3302	dmso reductase anchor subunit
J9260_15985	COG3328	transposase activity
J9260_15990	COG1061	Type III restriction enzyme res subunit
J9260_15995	COG4681	YaeQ
J9260_16000	COG0217	transcriptional regulatory protein
J9260_16005	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
J9260_16020	COG2983	Belongs to the UPF0260 family
J9260_16025	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J9260_16040	COG3954	Phosphoribulokinase
J9260_16060	COG1487	ribonuclease activity
J9260_16105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J9260_16115	COG0408	coproporphyrinogen oxidase activity
J9260_16125	COG1404	Belongs to the peptidase S8 family
J9260_16135	COG1595	DNA-templated transcription, initiation
J9260_16140	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
J9260_16145	COG0196	riboflavin kinase activity
J9260_16150	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J9260_16155	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J9260_16160	COG0540	Belongs to the ATCase OTCase family
J9260_16165	COG0129	dihydroxy-acid dehydratase activity
J9260_16170	COG1752	Esterase of the alpha-beta hydrolase superfamily
J9260_16185	COG3328	transposase activity
J9260_16205	COG0446	pyridine nucleotide-disulphide oxidoreductase
J9260_16215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J9260_16225	COG5001	Diguanylate cyclase
J9260_16225	COG4251	negative regulation of phosphorylation
J9260_16225	COG3706	GGDEF domain
J9260_16225	COG2203	Gaf domain
J9260_16270	COG1056	cytidyltransferase-related domain
J9260_16270	COG1051	belongs to the nudix hydrolase family
J9260_16275	COG4269	membrane
J9260_16290	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
J9260_16295	COG0826	peptidase U32
J9260_16300	COG1166	arginine decarboxylase activity
J9260_16310	COG3100	YcgL domain-containing protein
J9260_16330	COG0339	signal peptide processing
J9260_16340	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
J9260_16350	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
J9260_16355	COG0230	Belongs to the bacterial ribosomal protein bL34 family
J9260_16360	COG0594	ribonuclease P activity
J9260_16365	COG0706	membrane insertase activity
J9260_16370	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
J9260_16385	COG0009	L-threonylcarbamoyladenylate synthase
J9260_16395	COG0860	N-Acetylmuramoyl-L-alanine amidase
J9260_16400	COG0802	atpase or kinase
J9260_16410	COG2996	Protein conserved in bacteria
J9260_16420	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
J9260_16430	COG0140	phosphoribosyl-ATP diphosphatase activity
J9260_16435	COG0107	imidazoleglycerol-phosphate synthase activity
J9260_16440	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
J9260_16445	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J9260_16450	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J9260_16455	COG0126	phosphoglycerate kinase activity
J9260_16470	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J9260_16475	COG3383	formate dehydrogenase (NAD+) activity
J9260_16480	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
J9260_16485	COG3259	Nickel-dependent hydrogenase
J9260_16495	COG4953	penicillin-binding protein 1C
J9260_16515	COG1690	Belongs to the RtcB family
J9260_16540	COG0500	methyltransferase
J9260_16560	COG2081	HI0933 family
J9260_16575	COG3550	peptidyl-serine autophosphorylation
J9260_16595	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
J9260_16600	COG2922	Belongs to the Smg family
J9260_16605	COG0758	DNA mediated transformation
J9260_16610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J9260_16630	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J9260_16640	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J9260_16650	COG0166	Belongs to the GPI family
J9260_16655	COG0837	glucose binding
J9260_16660	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
J9260_16670	COG1640	4-alpha-glucanotransferase
J9260_16695	COG0297	glycogen (starch) synthase activity
J9260_16700	COG0058	SHG alpha-glucan phosphorylase activity
J9260_16710	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J9260_16715	COG2046	Belongs to the sulfate adenylyltransferase family
J9260_16730	COG0563	adenylate kinase activity
J9260_16735	COG1047	Peptidyl-prolyl cis-trans
J9260_16745	COG0205	6-phosphofructokinase activity
J9260_16755	COG0724	RNA recognition motif
J9260_16770	COG2048	Heterodisulfide reductase, subunit B
J9260_16775	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J9260_16785	COG1233	COG1233 Phytoene dehydrogenase and related
J9260_16790	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
J9260_16800	COG1253	flavin adenine dinucleotide binding
J9260_16810	COG0179	Fumarylacetoacetate (FAA) hydrolase
J9260_16815	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
J9260_16830	COG4636	protein conserved in cyanobacteria
J9260_16835	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
J9260_16840	COG3550	peptidyl-serine autophosphorylation
J9260_16850	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
J9260_16865	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J9260_16875	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
J9260_16885	COG0585	pseudouridine synthase activity
J9260_16890	COG0156	8-amino-7-oxononanoate synthase activity
J9260_16895	COG0425	Belongs to the sulfur carrier protein TusA family
J9260_16900	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J9260_16910	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J9260_16945	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J9260_17025	COG1652	LysM domain
J9260_17030	COG0242	peptide deformylase activity
J9260_17035	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
J9260_17050	COG5000	phosphorelay sensor kinase activity
J9260_17055	COG2204	response regulator
J9260_17060	COG0569	domain protein
J9260_17065	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J9260_17075	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
J9260_17080	COG2856	Zn peptidase
J9260_17090	COG1047	Peptidyl-prolyl cis-trans
J9260_17100	COG0151	Belongs to the GarS family
J9260_17115	COG0116	Belongs to the methyltransferase superfamily
J9260_17115	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
J9260_17120	COG3220	belongs to the UPF0276 family
J9260_17140	COG2176	DNA-directed DNA polymerase activity
J9260_17140	COG5002	protein histidine kinase activity
J9260_17145	COG0745	RESPONSE REGULATOR receiver
J9260_17150	COG5002	protein histidine kinase activity
J9260_17160	COG1758	RNA polymerase activity
J9260_17165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J9260_17175	COG0248	Ppx GppA phosphatase
J9260_17180	COG2354	Protein conserved in bacteria
J9260_17185	COG4804	nuclease activity
J9260_17210	COG0702	epimerase
J9260_17225	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
J9260_17250	COG3541	Predicted nucleotidyltransferase
J9260_17260	COG3177	Filamentation induced by cAMP protein fic
J9260_17270	COG2027	D-alanyl-D-alanine carboxypeptidase
J9260_17280	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J9260_17285	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
J9260_17295	COG0154	amidase activity
J9260_17300	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J9260_17305	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J9260_17325	COG2267	carboxylic ester hydrolase activity
J9260_17335	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
J9260_17340	COG1077	Cell shape determining protein MreB Mrl
J9260_17345	COG1792	Involved in formation and maintenance of cell shape
J9260_17355	COG1469	GTP cyclohydrolase I activity
J9260_17360	COG0330	HflC and HflK could
J9260_17365	COG1585	Membrane protein implicated in regulation of membrane protease activity
J9260_17385	COG5265	(ABC) transporter
J9260_17390	COG4232	protein-disulfide reductase activity
J9260_17410	COG0827	DNA restriction-modification system
J9260_17415	COG0827	DNA restriction-modification system
J9260_17420	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J9260_17425	COG1538	Outer membrane efflux protein
J9260_17430	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J9260_17460	COG2943	transferase activity, transferring hexosyl groups
J9260_17470	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
J9260_17505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J9260_17510	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J9260_17515	COG0438	transferase activity, transferring glycosyl groups
J9260_17530	COG0367	asparagine synthase
J9260_17535	COG2244	polysaccharide biosynthetic process
J9260_17545	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J9260_17565	COG0438	transferase activity, transferring glycosyl groups
J9260_17570	COG1216	Glycosyl transferase, family 2
J9260_17585	COG0037	tRNA processing
J9260_17590	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J9260_17600	COG0457	Tetratricopeptide repeat
J9260_17600	COG0463	Glycosyl transferase, family 2
J9260_17625	COG1317	bacterial-type flagellum organization
J9260_17640	COG4789	Type iii secretion
J9260_17650	COG4792	protein secretion
J9260_17655	COG4791	protein targeting
J9260_17660	COG4794	Type iii secretion
J9260_17665	COG4790	Type iii secretion
J9260_17710	COG4669	(LipO)protein
J9260_17715	COG1560	Kdo2-lipid A biosynthetic process
J9260_17720	COG1058	Belongs to the CinA family
J9260_17720	COG1546	Belongs to the CinA family
J9260_17725	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
J9260_17735	COG0483	inositol monophosphate 1-phosphatase activity
J9260_17740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J9260_17745	COG1187	pseudouridine synthase activity
J9260_17760	COG1132	(ABC) transporter
J9260_17785	COG1218	3'(2'),5'-bisphosphate nucleotidase
J9260_17790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J9260_17795	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J9260_17800	COG0501	Belongs to the peptidase M48B family
J9260_17810	COG1162	GTPase activity
J9260_17815	COG4191	Histidine kinase
J9260_17825	COG3038	cytochrome b561
J9260_17830	COG1741	Belongs to the pirin family
J9260_17835	COG0583	DNA-binding transcription factor activity
J9260_17840	COG0586	Pfam SNARE associated Golgi protein
J9260_17845	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
J9260_17850	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J9260_17855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J9260_17860	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
J9260_17950	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J9260_17970	COG1192	Involved in chromosome partitioning
J9260_18015	COG0489	protein tyrosine kinase activity
J9260_18055	COG1131	(ABC) transporter
J9260_18060	COG0842	Transport permease protein
J9260_18065	COG1404	Belongs to the peptidase S8 family
J9260_18490	COG1192	Involved in chromosome partitioning
J9260_18555	COG1192	Involved in chromosome partitioning