locus-tag	class	description
HGR01_00035	COG0837	glucose binding
HGR01_00060	COG2203	Gaf domain
HGR01_00060	COG3706	GGDEF domain
HGR01_00060	COG4251	negative regulation of phosphorylation
HGR01_00060	COG5001	Diguanylate cyclase
HGR01_00080	COG0277	FAD linked oxidase domain protein
HGR01_00095	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
HGR01_00100	COG1372	Participates in initiation and elongation during chromosome replication
HGR01_00100	COG0187	DNA topoisomerase II activity
HGR01_00105	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGR01_00110	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HGR01_00115	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGR01_00165	COG2084	Dehydrogenase
HGR01_00185	COG2203	Gaf domain
HGR01_00190	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
HGR01_00205	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HGR01_00220	COG3659	wide pore channel activity
HGR01_00225	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HGR01_00235	COG0129	dihydroxy-acid dehydratase activity
HGR01_00240	COG0583	DNA-binding transcription factor activity
HGR01_00245	COG0577	efflux transmembrane transporter activity
HGR01_00245	COG1136	(ABC) transporter
HGR01_00260	COG1136	(ABC) transporter
HGR01_00265	COG0577	efflux transmembrane transporter activity
HGR01_00265	COG1136	(ABC) transporter
HGR01_00285	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGR01_00295	COG1937	Protein conserved in bacteria
HGR01_00300	COG0596	Alpha beta hydrolase
HGR01_00305	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HGR01_00315	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HGR01_00315	COG0140	phosphoribosyl-ATP diphosphatase activity
HGR01_00320	COG4636	protein conserved in cyanobacteria
HGR01_00340	COG1216	Glycosyl transferase, family 2
HGR01_00350	COG1012	belongs to the aldehyde dehydrogenase family
HGR01_00435	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HGR01_00445	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HGR01_00530	COG0438	transferase activity, transferring glycosyl groups
HGR01_00540	COG0438	transferase activity, transferring glycosyl groups
HGR01_00555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HGR01_00560	COG0768	penicillin binding
HGR01_00565	COG2205	protein histidine kinase activity
HGR01_00590	COG1361	Conserved repeat domain
HGR01_00625	COG0745	RESPONSE REGULATOR receiver
HGR01_00655	COG0668	transmembrane transport
HGR01_00675	COG1845	cytochrome c oxidase, subunit III
HGR01_00690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGR01_00695	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HGR01_00705	COG0640	Transcriptional regulator
HGR01_00715	COG0446	pyridine nucleotide-disulphide oxidoreductase
HGR01_00725	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
HGR01_00740	COG1215	transferase activity, transferring glycosyl groups
HGR01_00745	COG2201	protein-glutamate methylesterase activity
HGR01_00780	COG0616	signal peptide processing
HGR01_00785	COG1304	FMN binding
HGR01_00795	COG1160	GTP binding
HGR01_00810	COG4106	trans-aconitate 2-methyltransferase activity
HGR01_00890	COG2831	hemolysin activation secretion protein
HGR01_00905	COG3063	Type IV pilus biogenesis stability protein PilW
HGR01_00910	COG0840	transmembrane signaling receptor activity
HGR01_00910	COG2203	Gaf domain
HGR01_00930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGR01_00935	COG2197	response regulator
HGR01_00985	COG5002	protein histidine kinase activity
HGR01_01000	COG1672	PFAM Archaeal ATPase
HGR01_01000	COG2319	Wd-40 repeat
HGR01_01010	COG3266	domain, Protein
HGR01_01010	COG0515	serine threonine protein kinase
HGR01_01050	COG0402	S-adenosylhomocysteine deaminase activity
HGR01_01055	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HGR01_01060	COG0271	Belongs to the BolA IbaG family
HGR01_01070	COG4935	Belongs to the peptidase S8 family
HGR01_01070	COG1404	Belongs to the peptidase S8 family
HGR01_01085	COG0590	tRNA wobble adenosine to inosine editing
HGR01_01105	COG1420	regulation of RNA biosynthetic process
HGR01_01115	COG1615	UPF0182 protein
HGR01_01130	COG1797	cobyrinic acid a,c-diamide synthase activity
HGR01_01145	COG1950	PFAM Membrane protein of
HGR01_01160	COG0666	response to abiotic stimulus
HGR01_01175	COG0702	epimerase
HGR01_01205	COG0052	Belongs to the universal ribosomal protein uS2 family
HGR01_01210	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
HGR01_01220	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HGR01_01225	COG0842	Transport permease protein
HGR01_01235	COG0842	Transport permease protein
HGR01_01235	COG1129	ABC transporter
HGR01_01240	COG1131	(ABC) transporter
HGR01_01250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGR01_01265	COG2326	polyphosphate kinase activity
HGR01_01290	COG0574	Belongs to the PEP-utilizing enzyme family
HGR01_01290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGR01_01305	COG4251	negative regulation of phosphorylation
HGR01_01310	COG0784	Response regulator, receiver
HGR01_01315	COG5002	protein histidine kinase activity
HGR01_01320	COG4251	negative regulation of phosphorylation
HGR01_01320	COG3706	GGDEF domain
HGR01_01320	COG5001	Diguanylate cyclase
HGR01_01320	COG2203	Gaf domain
HGR01_01325	COG5002	protein histidine kinase activity
HGR01_01335	COG4680	protein conserved in bacteria
HGR01_01340	COG0300	oxidoreductase activity
HGR01_01385	COG1122	ATPase activity
HGR01_01390	COG0357	Ribosomal RNA small subunit methyltransferase G
HGR01_01405	COG0515	serine threonine protein kinase
HGR01_01405	COG2815	serine threonine protein kinase
HGR01_01415	COG0784	Response regulator, receiver
HGR01_01415	COG2198	Histidine kinase
HGR01_01415	COG2205	protein histidine kinase activity
HGR01_01430	COG2815	serine threonine protein kinase
HGR01_01430	COG0515	serine threonine protein kinase
HGR01_01435	COG2815	serine threonine protein kinase
HGR01_01435	COG0515	serine threonine protein kinase
HGR01_01440	COG0515	serine threonine protein kinase
HGR01_01440	COG2815	serine threonine protein kinase
HGR01_01445	COG2815	serine threonine protein kinase
HGR01_01445	COG0515	serine threonine protein kinase
HGR01_01450	COG0515	serine threonine protein kinase
HGR01_01450	COG2815	serine threonine protein kinase
HGR01_01465	COG0538	isocitrate dehydrogenase activity
HGR01_01470	COG0515	serine threonine protein kinase
HGR01_01475	COG3842	ATPase activity
HGR01_01495	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
HGR01_01505	COG0460	homoserine dehydrogenase
HGR01_01510	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HGR01_01520	COG0572	uridine kinase
HGR01_01525	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
HGR01_01530	COG2205	protein histidine kinase activity
HGR01_01530	COG0784	Response regulator, receiver
HGR01_01565	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
HGR01_01575	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_01575	COG0515	serine threonine protein kinase
HGR01_01605	COG1234	tRNA 3'-trailer cleavage
HGR01_01615	COG1216	Glycosyl transferase, family 2
HGR01_01625	COG0438	transferase activity, transferring glycosyl groups
HGR01_01630	COG2226	methyltransferase
HGR01_01640	COG1132	(ABC) transporter
HGR01_01660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HGR01_01665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HGR01_01670	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HGR01_01675	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HGR01_01680	COG0438	transferase activity, transferring glycosyl groups
HGR01_01725	COG5398	heme oxygenase
HGR01_01730	COG0408	coproporphyrinogen oxidase activity
HGR01_01735	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HGR01_01755	COG0515	serine threonine protein kinase
HGR01_01775	COG0542	response to heat
HGR01_01785	COG1404	Belongs to the peptidase S8 family
HGR01_01805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HGR01_01815	COG1492	cobalamin metabolic process
HGR01_01840	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
HGR01_01855	COG0316	Belongs to the HesB IscA family
HGR01_01870	COG1090	epimerase
HGR01_01885	COG2217	Heavy metal translocating P-type atpase
HGR01_01945	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HGR01_01955	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HGR01_01960	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HGR01_01980	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
HGR01_01985	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
HGR01_01990	COG0170	dolichyl monophosphate biosynthetic process
HGR01_02040	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HGR01_02050	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HGR01_02050	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HGR01_02055	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
HGR01_02060	COG0148	phosphopyruvate hydratase activity
HGR01_02080	COG4802	Ferredoxin thioredoxin reductase catalytic beta chain
HGR01_02090	COG0285	dihydrofolate synthase activity
HGR01_02115	COG0612	Peptidase, M16
HGR01_02125	COG0024	Methionine aminopeptidase
HGR01_02135	COG0450	alkyl hydroperoxide reductase
HGR01_02160	COG0562	UDP-galactopyranose mutase
HGR01_02175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HGR01_02175	COG2205	protein histidine kinase activity
HGR01_02190	COG4999	Histidine kinase
HGR01_02190	COG3850	Histidine kinase
HGR01_02190	COG2205	protein histidine kinase activity
HGR01_02190	COG3437	response regulator, receiver
HGR01_02210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HGR01_02225	COG1136	(ABC) transporter
HGR01_02275	COG0693	protein deglycase activity
HGR01_02295	COG2267	carboxylic ester hydrolase activity
HGR01_02325	COG0438	transferase activity, transferring glycosyl groups
HGR01_02330	COG0438	transferase activity, transferring glycosyl groups
HGR01_02345	COG2244	polysaccharide biosynthetic process
HGR01_02350	COG0438	transferase activity, transferring glycosyl groups
HGR01_02375	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HGR01_02395	COG0583	DNA-binding transcription factor activity
HGR01_02400	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HGR01_02405	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HGR01_02410	COG4451	ribulose bisphosphate carboxylase, small
HGR01_02410	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HGR01_02415	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
HGR01_02420	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HGR01_02425	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HGR01_02430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HGR01_02435	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HGR01_02445	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HGR01_02445	COG1013	pyruvate-flavodoxin oxidoreductase activity
HGR01_02445	COG0674	pyruvate-flavodoxin oxidoreductase activity
HGR01_02445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HGR01_02450	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HGR01_02470	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
HGR01_02470	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HGR01_02485	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
HGR01_02490	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HGR01_02495	COG0494	nUDIX hydrolase
HGR01_02505	COG0133	tryptophan synthase activity
HGR01_02510	COG0023	Translation Initiation Factor
HGR01_02515	COG0401	homolog of Blt101
HGR01_02545	COG2852	Protein conserved in bacteria
HGR01_02565	COG0430	RNA-3'-phosphate cyclase activity
HGR01_02570	COG0514	ATP-dependent DNA helicase (RecQ)
HGR01_02580	COG1022	Amp-dependent synthetase and ligase
HGR01_02590	COG1333	cytochrome c biogenesis protein
HGR01_02595	COG4232	protein-disulfide reductase activity
HGR01_02600	COG0484	heat shock protein binding
HGR01_02605	COG1035	Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus
HGR01_02610	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
HGR01_02620	COG3239	Fatty acid desaturase
HGR01_02625	COG3239	Fatty acid desaturase
HGR01_02630	COG3239	Fatty acid desaturase
HGR01_02635	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HGR01_02650	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
HGR01_02660	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
HGR01_02660	COG0517	IMP dehydrogenase activity
HGR01_02660	COG0617	tRNA 3'-terminal CCA addition
HGR01_02665	COG4636	protein conserved in cyanobacteria
HGR01_02685	COG3794	PFAM blue (type 1) copper domain protein
HGR01_02690	COG2010	Cytochrome c
HGR01_02695	COG2010	Cytochrome c
HGR01_02710	COG0395	ABC-type sugar transport system, permease component
HGR01_02720	COG1007	ATP synthesis coupled electron transport
HGR01_02730	COG2205	protein histidine kinase activity
HGR01_02730	COG0784	Response regulator, receiver
HGR01_02730	COG2198	Histidine kinase
HGR01_02750	COG2072	flavoprotein involved in K transport
HGR01_02760	COG1028	Short-chain dehydrogenase reductase Sdr
HGR01_02765	COG2815	serine threonine protein kinase
HGR01_02765	COG0515	serine threonine protein kinase
HGR01_02770	COG0745	RESPONSE REGULATOR receiver
HGR01_02775	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HGR01_02790	COG0784	Response regulator, receiver
HGR01_02790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HGR01_02790	COG2198	Histidine kinase
HGR01_02790	COG2205	protein histidine kinase activity
HGR01_02795	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HGR01_02800	COG0406	alpha-ribazole phosphatase activity
HGR01_02810	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HGR01_02820	COG4262	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
HGR01_02835	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
HGR01_02850	COG1028	Short-chain dehydrogenase reductase Sdr
HGR01_02900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGR01_02925	COG0824	Thioesterase
HGR01_02950	COG0501	Belongs to the peptidase M48B family
HGR01_02960	COG0656	L-ascorbic acid biosynthetic process
HGR01_02995	COG1836	PFAM Integral membrane protein DUF92
HGR01_03005	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
HGR01_03020	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HGR01_03035	COG2319	Wd-40 repeat
HGR01_03035	COG1672	PFAM Archaeal ATPase
HGR01_03040	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HGR01_03080	COG0724	RNA recognition motif
HGR01_03105	COG0671	phosphoesterase, PA-phosphatase related
HGR01_03110	COG0456	acetyltransferase
HGR01_03110	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HGR01_03125	COG3958	Transketolase
HGR01_03140	COG1606	tRNA processing
HGR01_03185	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HGR01_03190	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
HGR01_03195	COG2912	Transglutaminase-like superfamily
HGR01_03215	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGR01_03230	COG0706	membrane insertase activity
HGR01_03240	COG0594	ribonuclease P activity
HGR01_03245	COG0230	Belongs to the bacterial ribosomal protein bL34 family
HGR01_03325	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HGR01_03330	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HGR01_03335	COG0321	lipoyl(octanoyl) transferase activity
HGR01_03355	COG1126	abc transporter atp-binding protein
HGR01_03360	COG0765	amino acid transport
HGR01_03365	COG3903	Transcriptional regulator
HGR01_03365	COG2319	Wd-40 repeat
HGR01_03370	COG2815	serine threonine protein kinase
HGR01_03370	COG0515	serine threonine protein kinase
HGR01_03385	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HGR01_03390	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HGR01_03395	COG0745	RESPONSE REGULATOR receiver
HGR01_03405	COG2119	membrane
HGR01_03420	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HGR01_03420	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HGR01_03425	COG2815	serine threonine protein kinase
HGR01_03425	COG0515	serine threonine protein kinase
HGR01_03470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HGR01_03485	COG2003	Belongs to the UPF0758 family
HGR01_03490	COG0066	3-isopropylmalate dehydratase activity
HGR01_03495	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
HGR01_03520	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HGR01_03555	COG1104	cysteine desulfurase activity
HGR01_03560	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HGR01_03615	COG0840	transmembrane signaling receptor activity
HGR01_03615	COG2203	Gaf domain
HGR01_03620	COG5002	protein histidine kinase activity
HGR01_03655	COG1032	radical SAM domain protein
HGR01_03665	COG0312	modulator of DNA gyrase
HGR01_03675	COG0312	modulator of DNA gyrase
HGR01_03690	COG0121	glutamine amidotransferase
HGR01_03705	COG0291	Belongs to the bacterial ribosomal protein bL35 family
HGR01_03710	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
HGR01_03735	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HGR01_03750	COG3903	Transcriptional regulator
HGR01_03750	COG2319	Wd-40 repeat
HGR01_03780	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGR01_03795	COG0515	serine threonine protein kinase
HGR01_03800	COG3266	domain, Protein
HGR01_03800	COG0515	serine threonine protein kinase
HGR01_03825	COG3781	membrane
HGR01_03830	COG2234	aminopeptidase activity
HGR01_03835	COG0443	Heat shock 70 kDa protein
HGR01_03840	COG0484	heat shock protein binding
HGR01_03850	COG1598	PFAM Uncharacterised protein family UPF0150
HGR01_03875	COG0436	Aminotransferase
HGR01_03895	COG0745	RESPONSE REGULATOR receiver
HGR01_03905	COG0784	Response regulator, receiver
HGR01_03905	COG2205	protein histidine kinase activity
HGR01_03905	COG5002	protein histidine kinase activity
HGR01_03915	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HGR01_03920	COG0284	orotidine-5'-phosphate decarboxylase activity
HGR01_03920	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HGR01_03925	COG0628	permease
HGR01_03970	COG5398	heme oxygenase
HGR01_03975	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HGR01_04000	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
HGR01_04020	COG1160	GTP binding
HGR01_04030	COG0149	triose-phosphate isomerase activity
HGR01_04035	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HGR01_04040	COG0330	HflC and HflK could
HGR01_04050	COG1596	polysaccharide export
HGR01_04055	COG1131	(ABC) transporter
HGR01_04060	COG0131	Imidazoleglycerol-phosphate dehydratase
HGR01_04065	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
HGR01_04070	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HGR01_04075	COG4372	Transposase
HGR01_04095	COG1185	polyribonucleotide nucleotidyltransferase activity
HGR01_04105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HGR01_04105	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HGR01_04120	COG4279	zinc finger
HGR01_04140	COG0393	Putative heavy-metal-binding
HGR01_04150	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
HGR01_04160	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_04160	COG0515	serine threonine protein kinase
HGR01_04165	COG0542	response to heat
HGR01_04170	COG0346	lactoylglutathione lyase activity
HGR01_04200	COG1217	gtp-binding protein TYPA
HGR01_04225	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HGR01_04230	COG3266	domain, Protein
HGR01_04230	COG0515	serine threonine protein kinase
HGR01_04235	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
HGR01_04240	COG1473	amidohydrolase
HGR01_04305	COG1215	transferase activity, transferring glycosyl groups
HGR01_04310	COG0793	Belongs to the peptidase S41A family
HGR01_04325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGR01_04335	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_04335	COG0515	serine threonine protein kinase
HGR01_04370	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
HGR01_04370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HGR01_04375	COG0456	acetyltransferase
HGR01_04415	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HGR01_04425	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HGR01_04430	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HGR01_04435	COG0750	zinc metalloprotease
HGR01_04440	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
HGR01_04470	COG2205	protein histidine kinase activity
HGR01_04475	COG1361	Conserved repeat domain
HGR01_04485	COG0419	ATPase involved in DNA repair
HGR01_04495	COG0668	transmembrane transport
HGR01_04505	COG2321	neutral zinc metallopeptidase
HGR01_04545	COG1132	(ABC) transporter
HGR01_04560	COG0519	Catalyzes the synthesis of GMP from XMP
HGR01_04570	COG0784	Response regulator, receiver
HGR01_04575	COG4251	negative regulation of phosphorylation
HGR01_04600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HGR01_04600	COG0072	phenylalanine-tRNA ligase activity
HGR01_04610	COG0612	Peptidase, M16
HGR01_04620	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HGR01_04625	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_04635	COG0678	peroxiredoxin activity
HGR01_04640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HGR01_04660	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HGR01_04665	COG4680	protein conserved in bacteria
HGR01_04675	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGR01_04685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HGR01_04700	COG0515	serine threonine protein kinase
HGR01_04705	COG0515	serine threonine protein kinase
HGR01_04715	COG0617	tRNA 3'-terminal CCA addition
HGR01_04725	COG1214	PFAM Peptidase M22, glycoprotease
HGR01_04785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HGR01_04790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HGR01_04795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HGR01_04795	COG1116	anion transmembrane transporter activity
HGR01_04800	COG1116	anion transmembrane transporter activity
HGR01_04805	COG2223	nitrite transmembrane transporter activity
HGR01_04810	COG0243	molybdopterin cofactor binding
HGR01_04830	COG0484	heat shock protein binding
HGR01_04850	COG1122	ATPase activity
HGR01_04860	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
HGR01_04865	COG0310	cobalt ion transport
HGR01_04885	COG0587	DNA-directed DNA polymerase activity
HGR01_04890	COG0154	amidase activity
HGR01_04895	COG1073	alpha beta
HGR01_04920	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HGR01_04925	COG0346	lactoylglutathione lyase activity
HGR01_04940	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
HGR01_04945	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
HGR01_04950	COG0546	phosphoglycolate phosphatase activity
HGR01_04980	COG1899	peptidyl-lysine modification to peptidyl-hypusine
HGR01_04985	COG0667	Aldo Keto reductase
HGR01_04990	COG0385	Bile acid
HGR01_05015	COG2226	methyltransferase
HGR01_05020	COG0546	phosphoglycolate phosphatase activity
HGR01_05135	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGR01_05235	COG1404	Belongs to the peptidase S8 family
HGR01_05320	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HGR01_05325	COG1111	helicase
HGR01_05325	COG1205	dead DEAH box helicase
HGR01_05330	COG5001	Diguanylate cyclase
HGR01_05330	COG2203	Gaf domain
HGR01_05330	COG3706	GGDEF domain
HGR01_05330	COG4251	negative regulation of phosphorylation
HGR01_05340	COG3706	GGDEF domain
HGR01_05355	COG3621	Patatin-like phospholipase
HGR01_05390	COG1595	DNA-templated transcription, initiation
HGR01_05420	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HGR01_05425	COG1899	peptidyl-lysine modification to peptidyl-hypusine
HGR01_05430	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HGR01_05440	COG2226	methyltransferase
HGR01_05460	COG0723	plastoquinol--plastocyanin reductase activity
HGR01_05555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HGR01_05560	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HGR01_05610	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HGR01_05615	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HGR01_05625	COG1205	dead DEAH box helicase
HGR01_05625	COG1111	helicase
HGR01_05805	COG2856	Zn peptidase
HGR01_05815	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HGR01_05820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HGR01_05825	COG2175	clavaminate synthase activity
HGR01_05830	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HGR01_05835	COG1116	anion transmembrane transporter activity
HGR01_05840	COG0778	Nitroreductase
HGR01_05845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HGR01_05850	COG3659	wide pore channel activity
HGR01_05855	COG0667	Aldo Keto reductase
HGR01_05860	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HGR01_05885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HGR01_05955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HGR01_05955	COG0784	Response regulator, receiver
HGR01_05960	COG2205	protein histidine kinase activity
HGR01_05980	COG1132	(ABC) transporter
HGR01_06005	COG0523	cobalamin synthesis protein
HGR01_06040	COG2166	iron-sulfur cluster assembly
HGR01_06060	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGR01_06065	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HGR01_06075	COG0515	serine threonine protein kinase
HGR01_06075	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_06090	COG0297	glycogen (starch) synthase activity
HGR01_06110	COG2124	cytochrome p450
HGR01_06125	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HGR01_06130	COG0003	Pfam Anion-transporting ATPase
HGR01_06155	COG2226	methyltransferase
HGR01_06165	COG0438	transferase activity, transferring glycosyl groups
HGR01_06190	COG0438	transferase activity, transferring glycosyl groups
HGR01_06205	COG0469	pyruvate kinase activity
HGR01_06220	COG0542	response to heat
HGR01_06225	COG0497	DNA recombination
HGR01_06230	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HGR01_06280	COG1429	ligase activity, forming nitrogen-metal bonds
HGR01_06310	COG4451	ribulose bisphosphate carboxylase, small
HGR01_06320	COG1850	ribulose-bisphosphate carboxylase activity
HGR01_06330	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
HGR01_06345	COG0542	response to heat
HGR01_06370	COG1773	rubredoxin
HGR01_06375	COG2081	HI0933 family
HGR01_06380	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HGR01_06400	COG0438	transferase activity, transferring glycosyl groups
HGR01_06400	COG0297	glycogen (starch) synthase activity
HGR01_06405	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HGR01_06420	COG0489	protein tyrosine kinase activity
HGR01_06430	COG1361	Conserved repeat domain
HGR01_06435	COG0110	maltose O-acetyltransferase activity
HGR01_06440	COG3447	MASE1 domain protein
HGR01_06440	COG5002	protein histidine kinase activity
HGR01_06440	COG5001	Diguanylate cyclase
HGR01_06445	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HGR01_06450	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
HGR01_06460	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
HGR01_06480	COG2814	Major facilitator Superfamily
HGR01_06485	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HGR01_06495	COG0589	response to stress
HGR01_06515	COG1028	Short-chain dehydrogenase reductase Sdr
HGR01_06545	COG4948	Mandelate Racemase Muconate Lactonizing
HGR01_06590	COG1193	negative regulation of DNA recombination
HGR01_06595	COG0516	GMP reductase activity
HGR01_06600	COG3118	belongs to the thioredoxin family
HGR01_06625	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HGR01_06655	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
HGR01_06660	COG0416	fatty acid biosynthetic process
HGR01_06665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
HGR01_06670	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HGR01_06675	COG0204	Acyl-transferase
HGR01_06675	COG0318	PFAM AMP-dependent synthetase and ligase
HGR01_06680	COG0628	permease
HGR01_06695	COG1575	Belongs to the MenA family. Type 1 subfamily
HGR01_06705	COG0318	PFAM AMP-dependent synthetase and ligase
HGR01_06710	COG0824	Thioesterase
HGR01_06755	COG0811	peptide transport
HGR01_06760	COG0848	biopolymer transport protein
HGR01_06785	COG0408	coproporphyrinogen oxidase activity
HGR01_06795	COG0489	protein tyrosine kinase activity
HGR01_06800	COG0772	Belongs to the SEDS family
HGR01_06815	COG0589	response to stress
HGR01_06815	COG0475	glutathione-regulated potassium exporter activity
HGR01_06820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HGR01_06825	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
HGR01_06840	COG1834	amidinotransferase
HGR01_06875	COG0504	CTP synthase activity
HGR01_06885	COG1940	carbohydrate kinase activity
HGR01_06895	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGR01_06900	COG0492	ferredoxin-NADP+ reductase activity
HGR01_06910	COG4968	Prepilin-type N-terminal cleavage methylation domain
HGR01_06925	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HGR01_06940	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
HGR01_06940	COG0028	Belongs to the TPP enzyme family
HGR01_06960	COG0515	serine threonine protein kinase
HGR01_06960	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_06970	COG5002	protein histidine kinase activity
HGR01_06975	COG1187	pseudouridine synthase activity
HGR01_06980	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
HGR01_06985	COG2161	toxin-antitoxin pair type II binding
HGR01_06995	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
HGR01_07015	COG1253	flavin adenine dinucleotide binding
HGR01_07020	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HGR01_07025	COG0673	inositol 2-dehydrogenase activity
HGR01_07030	COG0586	Pfam SNARE associated Golgi protein
HGR01_07045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HGR01_07050	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
HGR01_07065	COG0351	phosphomethylpyrimidine kinase
HGR01_07095	COG0584	glycerophosphoryl diester phosphodiesterase
HGR01_07100	COG1309	transcriptional regulator
HGR01_07115	COG1252	NADH dehydrogenase
HGR01_07125	COG0745	RESPONSE REGULATOR receiver
HGR01_07135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HGR01_07140	COG0814	amino acid
HGR01_07145	COG0784	Response regulator, receiver
HGR01_07145	COG5002	protein histidine kinase activity
HGR01_07160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HGR01_07165	COG0681	Belongs to the peptidase S26 family
HGR01_07170	COG0515	serine threonine protein kinase
HGR01_07170	COG3266	domain, Protein
HGR01_07185	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HGR01_07190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HGR01_07195	COG3118	belongs to the thioredoxin family
HGR01_07205	COG0583	DNA-binding transcription factor activity
HGR01_07210	COG0515	serine threonine protein kinase
HGR01_07220	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HGR01_07225	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HGR01_07230	COG0018	arginyl-trna synthetase
HGR01_07235	COG0561	phosphatase activity
HGR01_07240	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HGR01_07240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HGR01_07265	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HGR01_07270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HGR01_07295	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
HGR01_07310	COG0745	RESPONSE REGULATOR receiver
HGR01_07315	COG5002	protein histidine kinase activity
HGR01_07320	COG0704	Plays a role in the regulation of phosphate uptake
HGR01_07325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HGR01_07330	COG3659	wide pore channel activity
HGR01_07345	COG1215	transferase activity, transferring glycosyl groups
HGR01_07355	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HGR01_07390	COG4172	Belongs to the ABC transporter superfamily
HGR01_07395	COG0629	single-stranded DNA binding
HGR01_07410	COG3842	ATPase activity
HGR01_07420	COG0515	serine threonine protein kinase
HGR01_07420	COG2815	serine threonine protein kinase
HGR01_07430	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HGR01_07440	COG2197	response regulator
HGR01_07445	COG4251	negative regulation of phosphorylation
HGR01_07450	COG0784	Response regulator, receiver
HGR01_07455	COG0784	Response regulator, receiver
HGR01_07455	COG5002	protein histidine kinase activity
HGR01_07460	COG4999	Histidine kinase
HGR01_07460	COG3850	Histidine kinase
HGR01_07460	COG3437	response regulator, receiver
HGR01_07460	COG2205	protein histidine kinase activity
HGR01_07465	COG0784	Response regulator, receiver
HGR01_07485	COG0159	tryptophan synthase activity
HGR01_07535	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
HGR01_07540	COG1070	Carbohydrate kinase
HGR01_07565	COG1666	GTP binding
HGR01_07575	COG0857	belongs to the CobB CobQ family
HGR01_07585	COG1215	transferase activity, transferring glycosyl groups
HGR01_07590	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGR01_07605	COG1733	regulation of RNA biosynthetic process
HGR01_07615	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HGR01_07630	COG0488	(ABC) transporter
HGR01_07635	COG3937	granule-associated protein
HGR01_07640	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HGR01_07645	COG0631	protein serine/threonine phosphatase activity
HGR01_07655	COG0515	serine threonine protein kinase
HGR01_07675	COG0395	ABC-type sugar transport system, permease component
HGR01_07680	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HGR01_07685	COG5322	oxidoreductase activity
HGR01_07690	COG0825	malonyl-CoA metabolic process
HGR01_07695	COG0300	oxidoreductase activity
HGR01_07700	COG0302	gtp cyclohydrolase
HGR01_07705	COG0135	phosphoribosylanthranilate isomerase activity
HGR01_07715	COG1994	Peptidase M50
HGR01_07715	COG0517	IMP dehydrogenase activity
HGR01_07755	COG0616	signal peptide processing
HGR01_07770	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HGR01_07785	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
HGR01_07795	COG0137	argininosuccinate synthase activity
HGR01_07800	COG0586	Pfam SNARE associated Golgi protein
HGR01_07815	COG0360	Binds together with S18 to 16S ribosomal RNA
HGR01_07820	COG0179	Fumarylacetoacetate (FAA) hydrolase
HGR01_07835	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
HGR01_07840	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HGR01_07845	COG1058	Belongs to the CinA family
HGR01_07845	COG1546	Belongs to the CinA family
HGR01_07855	COG2226	methyltransferase
HGR01_07860	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HGR01_07875	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HGR01_07890	COG2205	protein histidine kinase activity
HGR01_07890	COG0784	Response regulator, receiver
HGR01_07920	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HGR01_07925	COG3409	Peptidoglycan-binding domain 1 protein
HGR01_07925	COG0793	Belongs to the peptidase S41A family
HGR01_07940	COG0010	Belongs to the arginase family
HGR01_07945	COG0438	transferase activity, transferring glycosyl groups
HGR01_07975	COG0009	L-threonylcarbamoyladenylate synthase
HGR01_07980	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
HGR01_08005	COG0574	Belongs to the PEP-utilizing enzyme family
HGR01_08005	COG3848	Pyruvate phosphate dikinase
HGR01_08020	COG2255	four-way junction helicase activity
HGR01_08025	COG0107	imidazoleglycerol-phosphate synthase activity
HGR01_08110	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HGR01_08125	COG2814	Major facilitator Superfamily
HGR01_08135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HGR01_08150	COG0435	Glutathione S-transferase
HGR01_08160	COG2197	response regulator
HGR01_08170	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HGR01_08180	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HGR01_08210	COG2197	response regulator
HGR01_08225	COG3854	ATPases associated with a variety of cellular activities
HGR01_08255	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HGR01_08265	COG0004	ammonium transporteR
HGR01_08270	COG1742	UPF0060 membrane protein
HGR01_08275	COG0004	ammonium transporteR
HGR01_08280	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HGR01_08295	COG0589	response to stress
HGR01_08295	COG0475	glutathione-regulated potassium exporter activity
HGR01_08300	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HGR01_08310	COG2363	Small membrane protein
HGR01_08335	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
HGR01_08340	COG2894	cell division
HGR01_08345	COG0850	regulation of cytokinetic process
HGR01_08370	COG1846	Transcriptional regulator
HGR01_08390	COG0515	serine threonine protein kinase
HGR01_08390	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_08425	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HGR01_08430	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HGR01_08440	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HGR01_08440	COG3266	domain, Protein
HGR01_08445	COG0123	including yeast histone deacetylase and acetoin utilization protein
HGR01_08460	COG0668	transmembrane transport
HGR01_08475	COG0683	leucine binding
HGR01_08480	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
HGR01_08500	COG0259	pyridoxamine-phosphate oxidase activity
HGR01_08505	COG0628	permease
HGR01_08515	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HGR01_08520	COG1166	arginine decarboxylase activity
HGR01_08525	COG0105	UTP biosynthetic process
HGR01_08530	COG0861	Integral membrane protein TerC family
HGR01_08540	COG2267	carboxylic ester hydrolase activity
HGR01_08560	COG1672	PFAM Archaeal ATPase
HGR01_08560	COG2319	Wd-40 repeat
HGR01_08575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HGR01_08580	COG3150	esterase
HGR01_08585	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HGR01_08615	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
HGR01_08620	COG3903	Transcriptional regulator
HGR01_08620	COG2319	Wd-40 repeat
HGR01_08635	COG0163	prenyltransferase activity
HGR01_08640	COG0557	exoribonuclease II activity
HGR01_08650	COG0740	serine-type endopeptidase activity
HGR01_08670	COG1331	Highly conserved protein containing a thioredoxin domain
HGR01_08680	COG0746	molybdenum cofactor guanylyltransferase activity
HGR01_08690	COG0672	)-iron permease
HGR01_08705	COG2132	Multicopper oxidase
HGR01_08710	COG0310	cobalt ion transport
HGR01_08720	COG1122	ATPase activity
HGR01_08755	COG0574	Belongs to the PEP-utilizing enzyme family
HGR01_08755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGR01_08760	COG1285	pathogenesis
HGR01_08770	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HGR01_08775	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HGR01_08790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HGR01_08850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HGR01_08855	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HGR01_08875	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HGR01_08880	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
HGR01_08885	COG0717	Belongs to the dCTP deaminase family
HGR01_08895	COG0563	adenylate kinase activity
HGR01_08900	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
HGR01_08905	COG0363	glucosamine-6-phosphate deaminase activity
HGR01_08910	COG1716	ATPase activity
HGR01_08935	COG0222	ribosome binding
HGR01_08985	COG0651	ATP synthesis coupled electron transport
HGR01_08990	COG1006	Multisubunit Na H antiporter MnhC subunit
HGR01_09035	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGR01_09095	COG1672	PFAM Archaeal ATPase
HGR01_09095	COG2319	Wd-40 repeat
HGR01_09120	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HGR01_09145	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
HGR01_09180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
HGR01_09190	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HGR01_09205	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HGR01_09210	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
HGR01_09215	COG2211	Major facilitator Superfamily
HGR01_09225	COG0028	Belongs to the TPP enzyme family
HGR01_09255	COG3321	synthase
HGR01_09255	COG1028	Short-chain dehydrogenase reductase Sdr
HGR01_09255	COG0604	alcohol dehydrogenase
HGR01_09265	COG4221	oxidoreductase activity
HGR01_09305	COG5000	phosphorelay sensor kinase activity
HGR01_09310	COG3852	Histidine kinase
HGR01_09315	COG3659	wide pore channel activity
HGR01_09330	COG0822	iron-sulfur transferase activity
HGR01_09355	COG3548	integral membrane protein
HGR01_09365	COG1366	Belongs to the anti-sigma-factor antagonist family
HGR01_09385	COG2208	phosphoserine phosphatase activity
HGR01_09385	COG2770	Histidine kinase
HGR01_09395	COG2124	cytochrome p450
HGR01_09410	COG3932	Exopolysaccharide synthesis, ExoD
HGR01_09415	COG0586	Pfam SNARE associated Golgi protein
HGR01_09440	COG5592	hemerythrin HHE cation binding domain
HGR01_09450	COG1473	amidohydrolase
HGR01_09470	COG1028	Short-chain dehydrogenase reductase Sdr
HGR01_09480	COG1247	-acetyltransferase
HGR01_09490	COG0752	glycyl-tRNA synthetase alpha subunit
HGR01_09520	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HGR01_09525	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
HGR01_09530	COG0475	glutathione-regulated potassium exporter activity
HGR01_09530	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HGR01_09545	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HGR01_09560	COG2203	Gaf domain
HGR01_09560	COG0840	transmembrane signaling receptor activity
HGR01_09565	COG2205	protein histidine kinase activity
HGR01_09580	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HGR01_09590	COG0484	heat shock protein binding
HGR01_09625	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
HGR01_09660	COG4191	Histidine kinase
HGR01_09665	COG5002	protein histidine kinase activity
HGR01_09670	COG0788	formyltetrahydrofolate deformylase activity
HGR01_09690	COG1131	(ABC) transporter
HGR01_09735	COG0328	RNA-DNA hybrid ribonuclease activity
HGR01_09755	COG0211	Belongs to the bacterial ribosomal protein bL27 family
HGR01_09760	COG0261	This protein binds to 23S rRNA in the presence of protein L20
HGR01_09820	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HGR01_09825	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HGR01_09830	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HGR01_09835	COG1773	rubredoxin
HGR01_09840	COG4447	cellulose binding
HGR01_09905	COG2319	Wd-40 repeat
HGR01_09905	COG4249	Peptidase C14 caspase catalytic subunit p20
HGR01_09920	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HGR01_09925	COG0189	ligase activity
HGR01_09930	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HGR01_09940	COG3751	2OG-Fe(II) oxygenase superfamily
HGR01_09945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HGR01_09955	COG0793	Belongs to the peptidase S41A family
HGR01_09960	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
HGR01_09975	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGR01_09990	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
HGR01_10015	COG2197	response regulator
HGR01_10020	COG0170	dolichyl monophosphate biosynthetic process
HGR01_10030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HGR01_10035	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HGR01_10040	COG0776	regulation of translation
HGR01_10050	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_10055	COG0404	The glycine cleavage system catalyzes the degradation of glycine
HGR01_10065	COG0509	glycine decarboxylation via glycine cleavage system
HGR01_10075	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HGR01_10075	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HGR01_10080	COG5002	protein histidine kinase activity
HGR01_10105	COG0508	dehydrogenase complex catalyzes the overall conversion of
HGR01_10120	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
HGR01_10195	COG4953	penicillin-binding protein 1C
HGR01_10200	COG2373	Large extracellular alpha-helical protein
HGR01_10240	COG2264	protein methyltransferase activity
HGR01_10255	COG0463	Glycosyl transferase, family 2
HGR01_10260	COG2326	polyphosphate kinase activity
HGR01_10270	COG0842	Transport permease protein
HGR01_10270	COG1129	ABC transporter
HGR01_10275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HGR01_10285	COG1316	TRANSCRIPTIONal
HGR01_10290	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_10295	COG0728	peptidoglycan biosynthetic process
HGR01_10340	COG0811	peptide transport
HGR01_10345	COG0848	biopolymer transport protein
HGR01_10365	COG3788	relative of glutathione S-transferase, MAPEG superfamily
HGR01_10395	COG2319	Wd-40 repeat
HGR01_10395	COG1672	PFAM Archaeal ATPase
HGR01_10430	COG0489	protein tyrosine kinase activity
HGR01_10475	COG0673	inositol 2-dehydrogenase activity
HGR01_10495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HGR01_10500	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HGR01_10515	COG0438	transferase activity, transferring glycosyl groups
HGR01_10540	COG0438	transferase activity, transferring glycosyl groups
HGR01_10550	COG0438	transferase activity, transferring glycosyl groups
HGR01_10550	COG0297	glycogen (starch) synthase activity
HGR01_10560	COG0110	maltose O-acetyltransferase activity
HGR01_10570	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
HGR01_10575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HGR01_10600	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
HGR01_10610	COG5002	protein histidine kinase activity
HGR01_10615	COG0745	RESPONSE REGULATOR receiver
HGR01_10630	COG0604	alcohol dehydrogenase
HGR01_10635	COG0412	Dienelactone hydrolase
HGR01_10680	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
HGR01_10685	COG0438	transferase activity, transferring glycosyl groups
HGR01_10690	COG2045	Belongs to the ComB family
HGR01_10735	COG2091	lysine biosynthetic process via aminoadipic acid
HGR01_10745	COG1131	(ABC) transporter
HGR01_10755	COG2261	transglycosylase associated protein
HGR01_10770	COG0826	peptidase U32
HGR01_10790	COG2133	pyrroloquinoline quinone binding
HGR01_10855	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HGR01_10860	COG0398	Pfam SNARE associated Golgi protein
HGR01_10870	COG0398	Pfam SNARE associated Golgi protein
HGR01_10895	COG4636	protein conserved in cyanobacteria
HGR01_10925	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
HGR01_10930	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
HGR01_10940	COG0473	3-isopropylmalate dehydrogenase activity
HGR01_10950	COG0668	transmembrane transport
HGR01_10975	COG0517	IMP dehydrogenase activity
HGR01_10975	COG1125	glycine betaine transport
HGR01_10990	COG0686	Belongs to the AlaDH PNT family
HGR01_11015	COG5002	protein histidine kinase activity
HGR01_11035	COG0784	Response regulator, receiver
HGR01_11050	COG0564	pseudouridine synthase activity
HGR01_11055	COG3118	belongs to the thioredoxin family
HGR01_11060	COG2264	protein methyltransferase activity
HGR01_11065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HGR01_11085	COG2201	protein-glutamate methylesterase activity
HGR01_11125	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HGR01_11130	COG3659	wide pore channel activity
HGR01_11140	COG0525	valine-tRNA ligase activity
HGR01_11150	COG2814	Major facilitator Superfamily
HGR01_11155	COG2971	BadF BadG BcrA BcrD
HGR01_11165	COG1401	restriction endodeoxyribonuclease activity
HGR01_11185	COG1619	proteins homologs of microcin C7 resistance protein MccF
HGR01_11190	COG0424	maF-like protein
HGR01_11210	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HGR01_11230	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HGR01_11235	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
HGR01_11265	COG5002	protein histidine kinase activity
HGR01_11265	COG0784	Response regulator, receiver
HGR01_11265	COG2198	Histidine kinase
HGR01_11270	COG3437	response regulator, receiver
HGR01_11275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HGR01_11275	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
HGR01_11280	COG2226	methyltransferase
HGR01_11295	COG1012	belongs to the aldehyde dehydrogenase family
HGR01_11305	COG1028	Short-chain dehydrogenase reductase Sdr
HGR01_11320	COG0459	protein refolding
HGR01_11325	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
HGR01_11340	COG2205	protein histidine kinase activity
HGR01_11340	COG2198	Histidine kinase
HGR01_11340	COG0784	Response regulator, receiver
HGR01_11355	COG1366	Belongs to the anti-sigma-factor antagonist family
HGR01_11360	COG1366	Belongs to the anti-sigma-factor antagonist family
HGR01_11370	COG0392	lysyltransferase activity
HGR01_11370	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HGR01_11380	COG2076	Multidrug Resistance protein
HGR01_11390	COG1309	transcriptional regulator
HGR01_11480	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HGR01_11490	COG5635	Nacht domain
HGR01_11490	COG2319	Wd-40 repeat
HGR01_11490	COG5635	Nacht domain
HGR01_11490	COG2319	Wd-40 repeat
HGR01_11530	COG0732	type I restriction modification DNA specificity domain
HGR01_11535	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
HGR01_11540	COG1672	PFAM Archaeal ATPase
HGR01_11540	COG2319	Wd-40 repeat
HGR01_11580	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HGR01_11635	COG0739	heme binding
HGR01_11650	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HGR01_11680	COG0405	Gamma-glutamyltransferase
HGR01_11695	COG0667	Aldo Keto reductase
HGR01_11705	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HGR01_11725	COG2124	cytochrome p450
HGR01_11755	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HGR01_11810	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
HGR01_11815	COG2211	Major facilitator Superfamily
HGR01_11830	COG0247	lactate metabolic process
HGR01_11835	COG0277	FAD linked oxidase domain protein
HGR01_11845	COG2205	protein histidine kinase activity
HGR01_11850	COG1252	NADH dehydrogenase
HGR01_11865	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HGR01_11870	COG0174	glutamine synthetase
HGR01_11885	COG1252	NADH dehydrogenase
HGR01_11895	COG1957	nucleoside hydrolase
HGR01_11915	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HGR01_11925	COG0783	Belongs to the Dps family
HGR01_11930	COG4572	Cation transport regulator
HGR01_11945	COG3237	CsbD-like
HGR01_11950	COG2261	transglycosylase associated protein
HGR01_11955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGR01_11975	COG0643	Histidine kinase
HGR01_11975	COG2198	Histidine kinase
HGR01_11975	COG0784	Response regulator, receiver
HGR01_11980	COG0745	RESPONSE REGULATOR receiver
HGR01_11990	COG0784	Response regulator, receiver
HGR01_11990	COG2205	protein histidine kinase activity
HGR01_12025	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HGR01_12040	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HGR01_12045	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
HGR01_12090	COG0330	HflC and HflK could
HGR01_12100	COG0735	belongs to the Fur family
HGR01_12105	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGR01_12110	COG0047	phosphoribosylformylglycinamidine synthase activity
HGR01_12125	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
HGR01_12135	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HGR01_12145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGR01_12145	COG0189	ligase activity
HGR01_12170	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HGR01_12180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HGR01_12190	COG0505	Belongs to the CarA family
HGR01_12200	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
HGR01_12205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGR01_12215	COG2267	carboxylic ester hydrolase activity
HGR01_12230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HGR01_12230	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HGR01_12235	COG0784	Response regulator, receiver
HGR01_12235	COG2205	protein histidine kinase activity
HGR01_12240	COG0589	response to stress
HGR01_12265	COG0343	queuine tRNA-ribosyltransferase activity
HGR01_12275	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
HGR01_12285	COG1040	competence protein
HGR01_12310	COG1028	Short-chain dehydrogenase reductase Sdr
HGR01_12325	COG4221	oxidoreductase activity
HGR01_12335	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
HGR01_12355	COG0300	oxidoreductase activity
HGR01_12375	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HGR01_12380	COG0438	transferase activity, transferring glycosyl groups
HGR01_12390	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HGR01_12425	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HGR01_12430	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
HGR01_12430	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HGR01_12455	COG1722	exodeoxyribonuclease VII activity
HGR01_12460	COG1570	exodeoxyribonuclease VII activity
HGR01_12475	COG0175	sulfate reduction
HGR01_12525	COG0587	DNA-directed DNA polymerase activity
HGR01_12530	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
HGR01_12535	COG1049	propionate catabolic process, 2-methylcitrate cycle
HGR01_12540	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HGR01_12550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HGR01_12565	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HGR01_12610	COG0469	pyruvate kinase activity
HGR01_12615	COG0589	response to stress
HGR01_12625	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HGR01_12625	COG0574	Belongs to the PEP-utilizing enzyme family
HGR01_12630	COG2814	Major facilitator Superfamily
HGR01_12640	COG0315	cyclic pyranopterin monophosphate synthase activity
HGR01_12680	COG0484	heat shock protein binding
HGR01_12690	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HGR01_12695	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
HGR01_12700	COG0019	diaminopimelate decarboxylase activity
HGR01_12705	COG0456	acetyltransferase
HGR01_12710	COG0542	response to heat
HGR01_12725	COG0681	Belongs to the peptidase S26 family
HGR01_12750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HGR01_12755	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HGR01_12760	COG0284	orotidine-5'-phosphate decarboxylase activity
HGR01_12770	COG2815	serine threonine protein kinase
HGR01_12770	COG0515	serine threonine protein kinase
HGR01_12775	COG1028	Short-chain dehydrogenase reductase Sdr
HGR01_12785	COG1132	(ABC) transporter
HGR01_12790	COG1132	(ABC) transporter
HGR01_12795	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HGR01_12860	COG0205	6-phosphofructokinase activity
HGR01_12875	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
HGR01_12880	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
HGR01_12885	COG0235	Class ii aldolase
HGR01_12910	COG1489	DNA binding
HGR01_12965	COG0860	N-Acetylmuramoyl-L-alanine amidase
HGR01_12975	COG1429	ligase activity, forming nitrogen-metal bonds
HGR01_12980	COG0297	glycogen (starch) synthase activity
HGR01_13015	COG0772	Belongs to the SEDS family
HGR01_13030	COG1672	PFAM Archaeal ATPase
HGR01_13030	COG2319	Wd-40 repeat
HGR01_13085	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
HGR01_13100	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HGR01_13115	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HGR01_13165	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HGR01_13175	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HGR01_13185	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HGR01_13190	COG0395	ABC-type sugar transport system, permease component
HGR01_13195	COG5002	protein histidine kinase activity
HGR01_13200	COG0303	'Molybdopterin
HGR01_13210	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HGR01_13215	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
HGR01_13220	COG0557	exoribonuclease II activity
HGR01_13230	COG2385	sporulation resulting in formation of a cellular spore
HGR01_13240	COG4208	sulfate ABC transporter
HGR01_13245	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HGR01_13250	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HGR01_13260	COG4974	Belongs to the 'phage' integrase family
HGR01_13265	COG0352	thiamine-phosphate diphosphorylase activity
HGR01_13310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGR01_13320	COG1151	hydroxylamine reductase activity
HGR01_13325	COG1034	ATP synthesis coupled electron transport
HGR01_13330	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HGR01_13335	COG3259	Nickel-dependent hydrogenase
HGR01_13345	COG1042	CoA-binding domain protein
HGR01_13345	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HGR01_13345	COG0045	succinate-CoA ligase (ADP-forming) activity
HGR01_13360	COG2046	Belongs to the sulfate adenylyltransferase family
HGR01_13370	COG1408	metallophosphoesterase
HGR01_13375	COG1408	metallophosphoesterase
HGR01_13380	COG1192	Involved in chromosome partitioning
HGR01_13390	COG1233	COG1233 Phytoene dehydrogenase and related
HGR01_13395	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HGR01_13425	COG2814	Major facilitator Superfamily
HGR01_13430	COG4572	Cation transport regulator
HGR01_13440	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HGR01_13450	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
HGR01_13470	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGR01_13485	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HGR01_13505	COG1309	transcriptional regulator
HGR01_13520	COG0577	efflux transmembrane transporter activity
HGR01_13520	COG1136	(ABC) transporter
HGR01_13530	COG0784	Response regulator, receiver
HGR01_13530	COG2198	Histidine kinase
HGR01_13530	COG5002	protein histidine kinase activity
HGR01_13560	COG2095	MarC family integral membrane protein
HGR01_13570	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HGR01_13575	COG0531	amino acid
HGR01_13580	COG2264	protein methyltransferase activity
HGR01_13585	COG1028	Short-chain dehydrogenase reductase Sdr
HGR01_13690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HGR01_13705	COG0356	it plays a direct role in the translocation of protons across the membrane
HGR01_13710	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGR01_13715	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HGR01_13720	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
HGR01_13725	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
HGR01_13730	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
HGR01_13735	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
HGR01_13765	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HGR01_13770	COG0724	RNA recognition motif
HGR01_13775	COG1830	Aldolase
HGR01_13780	COG4249	Peptidase C14 caspase catalytic subunit p20
HGR01_13780	COG2319	Wd-40 repeat
HGR01_13855	COG1028	Short-chain dehydrogenase reductase Sdr
HGR01_13860	COG1904	glucuronate isomerase
HGR01_13865	COG1609	Transcriptional regulator
HGR01_13870	COG3265	gluconokinase activity
HGR01_13880	COG1879	ABC-type sugar transport system periplasmic component
HGR01_13885	COG1879	ABC-type sugar transport system periplasmic component
HGR01_13890	COG1129	ABC transporter
HGR01_13895	COG1172	Belongs to the binding-protein-dependent transport system permease family
HGR01_13900	COG3659	wide pore channel activity
HGR01_13905	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HGR01_13905	COG0662	Cupin 2, conserved barrel domain protein
HGR01_13920	COG5001	Diguanylate cyclase
HGR01_13920	COG3300	MHYT domain
HGR01_13925	COG2205	protein histidine kinase activity
HGR01_13925	COG2198	Histidine kinase
HGR01_13925	COG0784	Response regulator, receiver
HGR01_13925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HGR01_13940	COG1968	undecaprenyl-diphosphatase activity
HGR01_13985	COG0515	serine threonine protein kinase
HGR01_13985	COG2815	serine threonine protein kinase
HGR01_14010	COG0180	Tryptophanyl-tRNA synthetase
HGR01_14025	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HGR01_14040	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HGR01_14045	COG1192	Involved in chromosome partitioning
HGR01_14050	COG1196	nuclear chromosome segregation
HGR01_14050	COG1674	ftsk spoiiie
HGR01_14065	COG1215	transferase activity, transferring glycosyl groups
HGR01_14075	COG0438	transferase activity, transferring glycosyl groups
HGR01_14105	COG2198	Histidine kinase
HGR01_14105	COG0784	Response regulator, receiver
HGR01_14105	COG5002	protein histidine kinase activity
HGR01_14150	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
HGR01_14155	COG0088	Forms part of the polypeptide exit tunnel
HGR01_14160	COG0089	rRNA binding
HGR01_14165	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HGR01_14170	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
HGR01_14175	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
HGR01_14180	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
HGR01_14190	COG0255	Belongs to the universal ribosomal protein uL29 family
HGR01_14195	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
HGR01_14200	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
HGR01_14205	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
HGR01_14210	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HGR01_14215	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
HGR01_14220	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
HGR01_14225	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
HGR01_14230	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
HGR01_14235	COG0200	Binds to the 23S rRNA
HGR01_14240	COG0201	protein transport
HGR01_14245	COG0563	adenylate kinase activity
HGR01_14250	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
HGR01_14255	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HGR01_14260	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HGR01_14265	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
HGR01_14270	COG0202	RNA polymerase activity
HGR01_14275	COG0203	ribosomal protein L17
HGR01_14280	COG0101	tRNA pseudouridine synthase activity
HGR01_14290	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HGR01_14295	COG0254	rRNA binding
HGR01_14300	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
HGR01_14325	COG0488	(ABC) transporter
HGR01_14330	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HGR01_14350	COG0683	leucine binding
HGR01_14355	COG0438	transferase activity, transferring glycosyl groups
HGR01_14365	COG1381	Involved in DNA repair and RecF pathway recombination
HGR01_14370	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
HGR01_14400	COG0799	negative regulation of ribosome biogenesis
HGR01_14405	COG0297	glycogen (starch) synthase activity
HGR01_14410	COG1126	abc transporter atp-binding protein
HGR01_14415	COG0765	amino acid transport
HGR01_14420	COG4597	amino acid ABC transporter
HGR01_14430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HGR01_14445	COG0602	queuosine metabolic process
HGR01_14465	COG0768	penicillin binding
HGR01_14470	COG0768	penicillin binding
HGR01_14475	COG3842	ATPase activity
HGR01_14490	COG1176	ABC-type spermidine putrescine transport system, permease component I
HGR01_14495	COG2203	Gaf domain
HGR01_14495	COG3706	GGDEF domain
HGR01_14495	COG4251	negative regulation of phosphorylation
HGR01_14495	COG5001	Diguanylate cyclase
HGR01_14505	COG2198	Histidine kinase
HGR01_14505	COG0643	Histidine kinase
HGR01_14505	COG0784	Response regulator, receiver
HGR01_14510	COG0840	transmembrane signaling receptor activity
HGR01_14510	COG2203	Gaf domain
HGR01_14525	COG2201	protein-glutamate methylesterase activity
HGR01_14530	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HGR01_14545	COG0515	serine threonine protein kinase
HGR01_14545	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_14550	COG1177	transmembrane transport
HGR01_14555	COG0438	transferase activity, transferring glycosyl groups
HGR01_14570	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HGR01_14585	COG2226	methyltransferase
HGR01_14605	COG3657	addiction module killer protein
HGR01_14620	COG0095	Lipoate-protein ligase
HGR01_14640	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HGR01_14680	COG1131	(ABC) transporter
HGR01_14695	COG0354	folic acid binding
HGR01_14730	COG5002	protein histidine kinase activity
HGR01_14735	COG5002	protein histidine kinase activity
HGR01_14735	COG5001	Diguanylate cyclase
HGR01_14735	COG3447	MASE1 domain protein
HGR01_14745	COG1528	Iron-storage protein
HGR01_14770	COG0363	glucosamine-6-phosphate deaminase activity
HGR01_14795	COG3634	alkyl hydroperoxide reductase activity
HGR01_14800	COG0300	oxidoreductase activity
HGR01_14810	COG0515	serine threonine protein kinase
HGR01_14810	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_14830	COG2885	chlorophyll binding
HGR01_14835	COG4932	domain protein
HGR01_14845	COG0515	serine threonine protein kinase
HGR01_14845	COG3266	domain, Protein
HGR01_14855	COG0123	including yeast histone deacetylase and acetoin utilization protein
HGR01_14905	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HGR01_14910	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HGR01_14930	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HGR01_14935	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HGR01_14940	COG0742	ribosomal rna small subunit methyltransferase
HGR01_14950	COG2010	Cytochrome c
HGR01_14965	COG1132	(ABC) transporter
HGR01_14980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HGR01_14985	COG0719	Fe-S assembly protein
HGR01_14990	COG0396	ATPase activity
HGR01_14995	COG0719	Fe-S assembly protein
HGR01_15015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
HGR01_15040	COG0439	Biotin carboxylase
HGR01_15055	COG0515	serine threonine protein kinase
HGR01_15085	COG1215	transferase activity, transferring glycosyl groups
HGR01_15090	COG1216	Glycosyl transferase, family 2
HGR01_15090	COG0463	Glycosyl transferase, family 2
HGR01_15105	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HGR01_15115	COG2226	methyltransferase
HGR01_15130	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HGR01_15155	COG1215	transferase activity, transferring glycosyl groups
HGR01_15160	COG4968	Prepilin-type N-terminal cleavage methylation domain
HGR01_15185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
HGR01_15190	COG0552	protein localization to endoplasmic reticulum
HGR01_15195	COG2208	phosphoserine phosphatase activity
HGR01_15245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HGR01_15250	COG0193	aminoacyl-tRNA hydrolase activity
HGR01_15255	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HGR01_15265	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
HGR01_15295	COG0714	Associated with various cellular activities
HGR01_15365	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
HGR01_15365	COG1672	PFAM Archaeal ATPase
HGR01_15385	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGR01_15400	COG3093	addiction module antidote protein HigA
HGR01_15410	COG0583	DNA-binding transcription factor activity
HGR01_15415	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HGR01_15425	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
HGR01_15430	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HGR01_15445	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
HGR01_15450	COG1027	Aspartate ammonia-lyase
HGR01_15475	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HGR01_15485	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HGR01_15520	COG1215	transferase activity, transferring glycosyl groups
HGR01_15545	COG0435	Glutathione S-transferase
HGR01_15550	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HGR01_15555	COG0457	Tetratricopeptide repeat
HGR01_15560	COG2135	peptidase activity
HGR01_15565	COG0625	glutathione transferase activity
HGR01_15570	COG1872	DUF167
HGR01_15580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGR01_15585	COG0346	lactoylglutathione lyase activity
HGR01_15595	COG0798	PFAM Bile acid sodium symporter
HGR01_15605	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HGR01_15610	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HGR01_15625	COG0515	serine threonine protein kinase
HGR01_15630	COG1672	PFAM Archaeal ATPase
HGR01_15630	COG2319	Wd-40 repeat
HGR01_15640	COG0436	Aminotransferase
HGR01_15645	COG0371	Dehydrogenase
HGR01_15665	COG0730	response to heat
HGR01_15680	COG0445	tRNA wobble uridine modification
HGR01_15710	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_15710	COG0515	serine threonine protein kinase
HGR01_15715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HGR01_15720	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HGR01_15720	COG1116	anion transmembrane transporter activity
HGR01_15885	COG3621	Patatin-like phospholipase
HGR01_15910	COG0515	serine threonine protein kinase
HGR01_15920	COG3437	response regulator, receiver
HGR01_15920	COG2205	protein histidine kinase activity
HGR01_15920	COG4999	Histidine kinase
HGR01_15920	COG3850	Histidine kinase
HGR01_15930	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HGR01_15935	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
HGR01_15940	COG0431	NADPH-dependent FMN reductase
HGR01_15945	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGR01_15950	COG1960	acyl-CoA dehydrogenase activity
HGR01_15980	COG1196	nuclear chromosome segregation
HGR01_15985	COG5002	protein histidine kinase activity
HGR01_15985	COG2205	protein histidine kinase activity
HGR01_15985	COG0784	Response regulator, receiver
HGR01_15990	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
HGR01_15995	COG1309	transcriptional regulator
HGR01_16005	COG1032	radical SAM domain protein
HGR01_16010	COG5002	protein histidine kinase activity
HGR01_16020	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
HGR01_16040	COG0463	Glycosyl transferase, family 2
HGR01_16055	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HGR01_16065	COG1301	dicarboxylic acid transport
HGR01_16070	COG0587	DNA-directed DNA polymerase activity
HGR01_16075	COG1028	Short-chain dehydrogenase reductase Sdr
HGR01_16110	COG0640	Transcriptional regulator
HGR01_16115	COG3118	belongs to the thioredoxin family
HGR01_16130	COG0625	glutathione transferase activity
HGR01_16185	COG5398	heme oxygenase
HGR01_16190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HGR01_16210	COG0438	transferase activity, transferring glycosyl groups
HGR01_16215	COG0438	transferase activity, transferring glycosyl groups
HGR01_16220	COG0450	alkyl hydroperoxide reductase
HGR01_16230	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HGR01_16235	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
HGR01_16280	COG0745	RESPONSE REGULATOR receiver
HGR01_16285	COG5002	protein histidine kinase activity
HGR01_16290	COG0288	reversible hydration of carbon dioxide
HGR01_16315	COG1361	Conserved repeat domain
HGR01_16315	COG3266	domain, Protein
HGR01_16315	COG2911	Protein conserved in bacteria
HGR01_16385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HGR01_16390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HGR01_16395	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGR01_16400	COG2048	Heterodisulfide reductase, subunit B
HGR01_16430	COG3903	Transcriptional regulator
HGR01_16430	COG3629	intracellular signal transduction
HGR01_16435	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HGR01_16455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HGR01_16465	COG2197	response regulator
HGR01_16470	COG4585	Histidine kinase
HGR01_16490	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HGR01_16515	COG2066	Belongs to the glutaminase family
HGR01_16525	COG2885	chlorophyll binding
HGR01_16530	COG2885	chlorophyll binding
HGR01_16545	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
HGR01_16580	COG1028	Short-chain dehydrogenase reductase Sdr
HGR01_16595	COG3852	Histidine kinase
HGR01_16600	COG0701	Predicted permease
HGR01_16615	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HGR01_16620	COG0592	DNA-directed DNA polymerase activity
HGR01_16625	COG2203	Gaf domain
HGR01_16625	COG5001	Diguanylate cyclase
HGR01_16625	COG4251	negative regulation of phosphorylation
HGR01_16625	COG5001	Diguanylate cyclase
HGR01_16625	COG3706	GGDEF domain
HGR01_16625	COG2203	Gaf domain
HGR01_16625	COG3706	GGDEF domain
HGR01_16625	COG4251	negative regulation of phosphorylation
HGR01_16630	COG0003	Pfam Anion-transporting ATPase
HGR01_16650	COG0004	ammonium transporteR
HGR01_16655	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HGR01_16660	COG2319	Wd-40 repeat
HGR01_16660	COG3903	Transcriptional regulator
HGR01_16665	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_16665	COG0515	serine threonine protein kinase
HGR01_16670	COG0004	ammonium transporteR
HGR01_16685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HGR01_16685	COG2022	thiamine diphosphate biosynthetic process
HGR01_16700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HGR01_16725	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
HGR01_16730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGR01_16735	COG0242	peptide deformylase activity
HGR01_16745	COG0625	glutathione transferase activity
HGR01_16755	COG2376	Dihydroxyacetone kinase
HGR01_16765	COG1461	Dihydroxyacetone kinase
HGR01_16780	COG0723	plastoquinol--plastocyanin reductase activity
HGR01_16785	COG0300	oxidoreductase activity
HGR01_16785	COG3000	fatty acid hydroxylase
HGR01_16800	COG0432	Pfam Uncharacterised protein family UPF0047
HGR01_16810	COG2994	toxin metabolic process
HGR01_16860	COG0438	transferase activity, transferring glycosyl groups
HGR01_16890	COG3852	Histidine kinase
HGR01_16895	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HGR01_16905	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
HGR01_16935	COG1116	anion transmembrane transporter activity
HGR01_16940	COG1116	anion transmembrane transporter activity
HGR01_16940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HGR01_16945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HGR01_16950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HGR01_16960	COG0475	glutathione-regulated potassium exporter activity
HGR01_16965	COG0347	Belongs to the P(II) protein family
HGR01_16995	COG0515	serine threonine protein kinase
HGR01_17005	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HGR01_17015	COG2217	Heavy metal translocating P-type atpase
HGR01_17030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HGR01_17040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HGR01_17050	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HGR01_17080	COG4106	trans-aconitate 2-methyltransferase activity
HGR01_17085	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
HGR01_17090	COG0667	Aldo Keto reductase
HGR01_17145	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HGR01_17150	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
HGR01_17180	COG4221	oxidoreductase activity
HGR01_17185	COG3903	Transcriptional regulator
HGR01_17185	COG2319	Wd-40 repeat
HGR01_17200	COG1649	PFAM Uncharacterised BCR, COG1649
HGR01_17205	COG0737	Belongs to the 5'-nucleotidase family
HGR01_17210	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_17210	COG0515	serine threonine protein kinase
HGR01_17230	COG0659	secondary active sulfate transmembrane transporter activity
HGR01_17260	COG3239	Fatty acid desaturase
HGR01_17285	COG3266	domain, Protein
HGR01_17285	COG0515	serine threonine protein kinase
HGR01_17290	COG0515	serine threonine protein kinase
HGR01_17430	COG2205	protein histidine kinase activity
HGR01_17430	COG2202	Pas domain
HGR01_17445	COG2198	Histidine kinase
HGR01_17445	COG2205	protein histidine kinase activity
HGR01_17445	COG0784	Response regulator, receiver
HGR01_17455	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HGR01_17460	COG0375	protein maturation
HGR01_17520	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HGR01_17530	COG0038	chloride channel
HGR01_17540	COG1959	2 iron, 2 sulfur cluster binding
HGR01_17545	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
HGR01_17550	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
HGR01_17565	COG0438	transferase activity, transferring glycosyl groups
HGR01_17575	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HGR01_17580	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
HGR01_17585	COG0793	Belongs to the peptidase S41A family
HGR01_17635	COG5635	Nacht domain
HGR01_17635	COG2319	Wd-40 repeat
HGR01_17640	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HGR01_17655	COG1126	abc transporter atp-binding protein
HGR01_17660	COG0765	amino acid transport
HGR01_17665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HGR01_17675	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HGR01_17690	COG1079	Belongs to the binding-protein-dependent transport system permease family
HGR01_17695	COG4603	Belongs to the binding-protein-dependent transport system permease family
HGR01_17700	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HGR01_17705	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HGR01_17730	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
HGR01_17735	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HGR01_17735	COG0519	Catalyzes the synthesis of GMP from XMP
HGR01_17740	COG1230	cation diffusion facilitator family transporter
HGR01_17755	COG0436	Aminotransferase
HGR01_17760	COG0463	Glycosyl transferase, family 2
HGR01_17760	COG0457	Tetratricopeptide repeat
HGR01_17780	COG2261	transglycosylase associated protein
HGR01_17785	COG3546	catalase activity
HGR01_17795	COG5001	Diguanylate cyclase
HGR01_17795	COG4251	negative regulation of phosphorylation
HGR01_17795	COG2203	Gaf domain
HGR01_17795	COG3706	GGDEF domain
HGR01_17800	COG2988	succinylglutamate desuccinylase activity
HGR01_17805	COG0583	DNA-binding transcription factor activity
HGR01_17820	COG1121	(ABC) transporter
HGR01_17825	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HGR01_17865	COG0784	Response regulator, receiver
HGR01_17870	COG2203	Gaf domain
HGR01_17870	COG0840	transmembrane signaling receptor activity
HGR01_17895	COG0071	Belongs to the small heat shock protein (HSP20) family
HGR01_17905	COG0784	Response regulator, receiver
HGR01_17905	COG2198	Histidine kinase
HGR01_17905	COG5002	protein histidine kinase activity
HGR01_17935	COG2197	response regulator
HGR01_17940	COG3850	Histidine kinase
HGR01_17940	COG3437	response regulator, receiver
HGR01_17940	COG4999	Histidine kinase
HGR01_17940	COG2205	protein histidine kinase activity
HGR01_17945	COG4095	Psort location CytoplasmicMembrane, score
HGR01_17985	COG0667	Aldo Keto reductase
HGR01_17990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGR01_18015	COG0515	serine threonine protein kinase
HGR01_18015	COG2815	serine threonine protein kinase
HGR01_18020	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HGR01_18035	COG3246	L-lysine catabolic process to acetate
HGR01_18045	COG0251	oxidation-reduction process
HGR01_18055	COG0124	histidyl-tRNA synthetase
HGR01_18120	COG1842	Phage shock protein A
HGR01_18125	COG1842	Phage shock protein A
HGR01_18130	COG3118	belongs to the thioredoxin family
HGR01_18135	COG0436	Aminotransferase
HGR01_18145	COG0322	excinuclease ABC activity
HGR01_18165	COG0820	rRNA (adenine-C2-)-methyltransferase activity
HGR01_18170	COG3852	Histidine kinase
HGR01_18200	COG0653	protein targeting
HGR01_18210	COG0288	reversible hydration of carbon dioxide
HGR01_18230	COG4999	Histidine kinase
HGR01_18230	COG3850	Histidine kinase
HGR01_18230	COG3437	response regulator, receiver
HGR01_18230	COG2205	protein histidine kinase activity
HGR01_18270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGR01_18280	COG1120	ATPase activity
HGR01_18335	COG0358	DNA primase activity
HGR01_18350	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
HGR01_18360	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HGR01_18370	COG1285	pathogenesis
HGR01_18405	COG0731	radical SAM domain protein
HGR01_18425	COG0784	Response regulator, receiver
HGR01_18425	COG5002	protein histidine kinase activity
HGR01_18440	COG0515	serine threonine protein kinase
HGR01_18460	COG0670	Belongs to the BI1 family
HGR01_18475	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
HGR01_18475	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
HGR01_18500	COG0571	ribonuclease III activity
HGR01_18505	COG2205	protein histidine kinase activity
HGR01_18505	COG3437	response regulator, receiver
HGR01_18505	COG3850	Histidine kinase
HGR01_18505	COG4999	Histidine kinase
HGR01_18510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HGR01_18515	COG1116	anion transmembrane transporter activity
HGR01_18515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HGR01_18520	COG1116	anion transmembrane transporter activity
HGR01_18530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HGR01_18555	COG2205	protein histidine kinase activity
HGR01_18555	COG4191	Histidine kinase
HGR01_18555	COG0745	RESPONSE REGULATOR receiver
HGR01_18570	COG2755	lipolytic protein G-D-S-L family
HGR01_18570	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HGR01_18630	COG0588	phosphoglycerate mutase activity
HGR01_18635	COG1132	(ABC) transporter
HGR01_18660	COG5002	protein histidine kinase activity
HGR01_18685	COG2223	nitrite transmembrane transporter activity
HGR01_18690	COG4106	trans-aconitate 2-methyltransferase activity
HGR01_18710	COG0318	PFAM AMP-dependent synthetase and ligase
HGR01_18715	COG0318	PFAM AMP-dependent synthetase and ligase
HGR01_18725	COG1012	belongs to the aldehyde dehydrogenase family
HGR01_18755	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGR01_18770	COG2217	Heavy metal translocating P-type atpase
HGR01_18810	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HGR01_18830	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
HGR01_18850	COG0582	viral genome integration into host DNA
HGR01_18875	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HGR01_18880	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
HGR01_18890	COG0318	PFAM AMP-dependent synthetase and ligase
HGR01_18895	COG1289	transmembrane transporter activity
HGR01_18905	COG0748	coenzyme F420 binding
HGR01_18920	COG0668	transmembrane transport
HGR01_18970	COG1028	Short-chain dehydrogenase reductase Sdr
HGR01_18975	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HGR01_18980	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HGR01_19000	COG0330	HflC and HflK could
HGR01_19010	COG0730	response to heat
HGR01_19015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HGR01_19075	COG3210	domain, Protein
HGR01_19085	COG3210	domain, Protein
HGR01_19100	COG0018	arginyl-trna synthetase
HGR01_19110	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
HGR01_19165	COG2197	response regulator
HGR01_19175	COG2205	protein histidine kinase activity
HGR01_19175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HGR01_19185	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HGR01_19190	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HGR01_19200	COG3852	Histidine kinase
HGR01_19210	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HGR01_19225	COG2066	Belongs to the glutaminase family
HGR01_19230	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HGR01_19235	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
HGR01_19235	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
HGR01_19240	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HGR01_19255	COG2319	Wd-40 repeat
HGR01_19290	COG1741	Belongs to the pirin family
HGR01_19295	COG0783	Belongs to the Dps family
HGR01_19305	COG0667	Aldo Keto reductase
HGR01_19310	COG2207	Transcriptional regulator
HGR01_19310	COG3708	Transcriptional regulator
HGR01_19325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HGR01_19350	COG4106	trans-aconitate 2-methyltransferase activity
HGR01_19360	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HGR01_19375	COG0724	RNA recognition motif
HGR01_19380	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HGR01_19485	COG0339	signal peptide processing
HGR01_19545	COG0415	Belongs to the DNA photolyase family
HGR01_19550	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HGR01_19555	COG0830	nickel cation binding
HGR01_19560	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
HGR01_19565	COG0784	Response regulator, receiver
HGR01_19565	COG2205	protein histidine kinase activity
HGR01_19575	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HGR01_19580	COG3536	Protein conserved in bacteria
HGR01_19590	COG0138	bifunctional purine biosynthesis protein purh
HGR01_19620	COG0745	RESPONSE REGULATOR receiver
HGR01_19640	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
HGR01_19665	COG0456	acetyltransferase
HGR01_19680	COG2223	nitrite transmembrane transporter activity
HGR01_19710	COG0419	ATPase involved in DNA repair
HGR01_19745	COG0475	glutathione-regulated potassium exporter activity
HGR01_19750	COG0475	glutathione-regulated potassium exporter activity
HGR01_19770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HGR01_19810	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HGR01_19820	COG2815	serine threonine protein kinase
HGR01_19820	COG0515	serine threonine protein kinase
HGR01_19840	COG0156	8-amino-7-oxononanoate synthase activity
HGR01_19845	COG0632	four-way junction helicase activity
HGR01_19850	COG0561	phosphatase activity
HGR01_19855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HGR01_19865	COG3228	Belongs to the MtfA family
HGR01_19870	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
HGR01_19890	COG3210	domain, Protein
HGR01_19905	COG0110	maltose O-acetyltransferase activity
HGR01_19920	COG0784	Response regulator, receiver
HGR01_19920	COG2205	protein histidine kinase activity
HGR01_19925	COG1943	Transposase
HGR01_19940	COG5002	protein histidine kinase activity
HGR01_19970	COG2319	Wd-40 repeat
HGR01_19970	COG1672	PFAM Archaeal ATPase
HGR01_19995	COG1231	oxidoreductase activity
HGR01_20080	COG1959	2 iron, 2 sulfur cluster binding
HGR01_20085	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HGR01_20090	COG0121	glutamine amidotransferase
HGR01_20095	COG0515	serine threonine protein kinase
HGR01_20095	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HGR01_20100	COG0753	catalase activity
HGR01_20120	COG2217	Heavy metal translocating P-type atpase
HGR01_20170	COG4191	Histidine kinase
HGR01_20195	COG0515	serine threonine protein kinase
HGR01_20220	COG4191	Histidine kinase
HGR01_20260	COG0778	Nitroreductase
HGR01_20265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGR01_20285	COG2205	protein histidine kinase activity
HGR01_20310	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HGR01_20330	COG0386	Belongs to the glutathione peroxidase family
HGR01_20340	COG1252	NADH dehydrogenase
HGR01_20360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HGR01_20360	COG4191	Histidine kinase
HGR01_20370	COG0678	peroxiredoxin activity
HGR01_20370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HGR01_20385	COG4251	negative regulation of phosphorylation
HGR01_20390	COG0784	Response regulator, receiver
HGR01_20400	COG2205	protein histidine kinase activity
HGR01_20420	COG1309	transcriptional regulator
HGR01_20435	COG0501	Belongs to the peptidase M48B family
HGR01_20440	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
HGR01_20450	COG0071	Belongs to the small heat shock protein (HSP20) family
HGR01_20460	COG0515	serine threonine protein kinase
HGR01_20460	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_20475	COG0515	serine threonine protein kinase
HGR01_20475	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_20505	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HGR01_20510	COG1175	transmembrane transport
HGR01_20520	COG0745	RESPONSE REGULATOR receiver
HGR01_20525	COG2183	response to ionizing radiation
HGR01_20535	COG1950	PFAM Membrane protein of
HGR01_20555	COG2010	Cytochrome c
HGR01_20565	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HGR01_20580	COG0745	RESPONSE REGULATOR receiver
HGR01_20585	COG0697	spore germination
HGR01_20600	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
HGR01_20620	COG0515	serine threonine protein kinase
HGR01_20620	COG2815	serine threonine protein kinase
HGR01_20640	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
HGR01_20775	COG2205	protein histidine kinase activity
HGR01_20780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HGR01_20805	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HGR01_20810	COG0581	inorganic phosphate transmembrane transporter activity
HGR01_20825	COG0640	Transcriptional regulator
HGR01_20865	COG0811	peptide transport
HGR01_20875	COG0628	permease
HGR01_20890	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
HGR01_20900	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
HGR01_20930	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HGR01_20950	COG0038	chloride channel
HGR01_20960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HGR01_20980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGR01_20990	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
HGR01_21015	COG1748	Saccharopine dehydrogenase
HGR01_21025	COG1459	type II secretion system
HGR01_21035	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
HGR01_21040	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HGR01_21045	COG0443	Heat shock 70 kDa protein
HGR01_21050	COG0484	heat shock protein binding
HGR01_21060	COG1162	GTPase activity
HGR01_21065	COG1543	Belongs to the glycosyl hydrolase 57 family
HGR01_21070	COG1252	NADH dehydrogenase
HGR01_21085	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HGR01_21090	COG0671	phosphoesterase, PA-phosphatase related
HGR01_21100	COG1480	7TM receptor with intracellular HD hydrolase
HGR01_21120	COG3394	polysaccharide catabolic process
HGR01_21180	COG0151	Belongs to the GarS family
HGR01_21185	COG5002	protein histidine kinase activity
HGR01_21200	COG0515	serine threonine protein kinase
HGR01_21210	COG0515	serine threonine protein kinase
HGR01_21230	COG5002	protein histidine kinase activity
HGR01_21235	COG0745	RESPONSE REGULATOR receiver
HGR01_21255	COG1404	Belongs to the peptidase S8 family
HGR01_21285	COG1404	Belongs to the peptidase S8 family
HGR01_21340	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HGR01_21385	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
HGR01_21400	COG1361	Conserved repeat domain
HGR01_21460	COG0443	Heat shock 70 kDa protein
HGR01_21480	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_21480	COG0515	serine threonine protein kinase
HGR01_21545	COG0514	ATP-dependent DNA helicase (RecQ)
HGR01_21575	COG1372	Participates in initiation and elongation during chromosome replication
HGR01_21575	COG0305	Participates in initiation and elongation during chromosome replication
HGR01_21575	COG1372	Participates in initiation and elongation during chromosome replication
HGR01_21575	COG0305	Participates in initiation and elongation during chromosome replication
HGR01_21600	COG4644	lycopene metabolic process
HGR01_21720	COG0546	phosphoglycolate phosphatase activity
HGR01_21735	COG0459	protein refolding
HGR01_21780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGR01_21790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGR01_21795	COG2814	Major facilitator Superfamily
HGR01_21800	COG1324	tolerance protein
HGR01_21805	COG0456	acetyltransferase
HGR01_21810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HGR01_21835	COG4783	chaperone-mediated protein folding
HGR01_21850	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
HGR01_21865	COG0314	molybdopterin synthase activity
HGR01_21885	COG4242	Belongs to the peptidase S51 family
HGR01_21895	COG0189	ligase activity
HGR01_21895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGR01_21900	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HGR01_21905	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HGR01_21915	COG1254	Belongs to the acylphosphatase family
HGR01_21920	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HGR01_21925	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HGR01_21930	COG0191	fructose-bisphosphate aldolase activity
HGR01_21960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HGR01_21980	COG0432	Pfam Uncharacterised protein family UPF0047
HGR01_22040	COG0456	acetyltransferase
HGR01_22060	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HGR01_22070	COG2226	methyltransferase
HGR01_22085	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HGR01_22090	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HGR01_22115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HGR01_22140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HGR01_22145	COG0346	lactoylglutathione lyase activity
HGR01_22170	COG4106	trans-aconitate 2-methyltransferase activity
HGR01_22195	COG0697	spore germination
HGR01_22200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGR01_22205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGR01_22220	COG1028	Short-chain dehydrogenase reductase Sdr
HGR01_22225	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HGR01_22225	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HGR01_22240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGR01_22250	COG2072	flavoprotein involved in K transport
HGR01_22255	COG0667	Aldo Keto reductase
HGR01_22260	COG0778	Nitroreductase
HGR01_22290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HGR01_22290	COG0426	domain, Protein
HGR01_22295	COG0426	domain, Protein
HGR01_22295	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HGR01_22300	COG0157	Belongs to the NadC ModD family
HGR01_22335	COG0745	RESPONSE REGULATOR receiver
HGR01_22340	COG0429	hydrolase of the alpha beta-hydrolase fold
HGR01_22350	COG0584	glycerophosphoryl diester phosphodiesterase
HGR01_22390	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HGR01_22395	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HGR01_22405	COG5002	protein histidine kinase activity
HGR01_22405	COG2198	Histidine kinase
HGR01_22405	COG0784	Response regulator, receiver
HGR01_22415	COG0109	protoheme IX farnesyltransferase activity
HGR01_22425	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HGR01_22430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HGR01_22435	COG1845	cytochrome c oxidase, subunit III
HGR01_22440	COG0515	serine threonine protein kinase
HGR01_22440	COG3266	domain, Protein
HGR01_22455	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
HGR01_22460	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HGR01_22465	COG0556	nucleotide-excision repair
HGR01_22480	COG1361	Conserved repeat domain
HGR01_22485	COG4636	protein conserved in cyanobacteria
HGR01_22530	COG5002	protein histidine kinase activity
HGR01_22540	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HGR01_22545	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HGR01_22555	COG2205	protein histidine kinase activity
HGR01_22555	COG2202	Pas domain
HGR01_22570	COG0735	belongs to the Fur family
HGR01_22575	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGR01_22580	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
HGR01_22585	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HGR01_22590	COG0537	adenosine 5'-monophosphoramidase activity
HGR01_22595	COG0606	chelatase, subunit chli
HGR01_22615	COG0745	RESPONSE REGULATOR receiver
HGR01_22655	COG3552	Protein containing von Willebrand factor type A (VWA) domain
HGR01_22660	COG0714	Associated with various cellular activities
HGR01_22710	COG4231	catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates
HGR01_22735	COG4585	Histidine kinase
HGR01_22740	COG2197	response regulator
HGR01_22770	COG0110	maltose O-acetyltransferase activity
HGR01_22775	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
HGR01_22810	COG0723	plastoquinol--plastocyanin reductase activity
HGR01_22830	COG5001	Diguanylate cyclase
HGR01_22830	COG4251	negative regulation of phosphorylation
HGR01_22830	COG3706	GGDEF domain
HGR01_22830	COG2203	Gaf domain
HGR01_22835	COG0210	DNA helicase
HGR01_22865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HGR01_22875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGR01_22900	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HGR01_22910	COG0673	inositol 2-dehydrogenase activity
HGR01_22945	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
HGR01_22955	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HGR01_22960	COG5398	heme oxygenase
HGR01_22965	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HGR01_22970	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
HGR01_22970	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HGR01_22970	COG0674	pyruvate-flavodoxin oxidoreductase activity
HGR01_22970	COG1013	pyruvate-flavodoxin oxidoreductase activity
HGR01_22980	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HGR01_22990	COG0815	Transfers the fatty acyl group on membrane lipoproteins
HGR01_23030	COG0463	Glycosyl transferase, family 2
HGR01_23045	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGR01_23055	COG1475	DNA binding
HGR01_23060	COG2852	Protein conserved in bacteria
HGR01_23090	COG0604	alcohol dehydrogenase
HGR01_23090	COG3321	synthase
HGR01_23095	COG3321	synthase
HGR01_23095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HGR01_23095	COG1028	Short-chain dehydrogenase reductase Sdr
HGR01_23095	COG4221	oxidoreductase activity
HGR01_23105	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGR01_23105	COG0300	oxidoreductase activity
HGR01_23105	COG3321	synthase
HGR01_23105	COG4221	oxidoreductase activity
HGR01_23110	COG2070	2-Nitropropane dioxygenase
HGR01_23110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HGR01_23115	COG3320	Male sterility
HGR01_23115	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGR01_23125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGR01_23230	COG1487	ribonuclease activity
HGR01_23310	COG0033	Phosphoglucomutase
HGR01_23315	COG1324	tolerance protein
HGR01_23320	COG0668	transmembrane transport
HGR01_23325	COG1132	(ABC) transporter
HGR01_23340	COG2304	oxidoreductase activity
HGR01_23355	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HGR01_23430	COG0222	ribosome binding
HGR01_23460	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HGR01_23505	COG4804	nuclease activity
HGR01_23510	COG2442	InterPro IPR007367
HGR01_23530	COG0300	oxidoreductase activity
HGR01_23540	COG5001	Diguanylate cyclase
HGR01_23540	COG4251	negative regulation of phosphorylation
HGR01_23540	COG3706	GGDEF domain
HGR01_23540	COG2203	Gaf domain
HGR01_23540	COG5001	Diguanylate cyclase
HGR01_23540	COG4251	negative regulation of phosphorylation
HGR01_23540	COG3706	GGDEF domain
HGR01_23540	COG2203	Gaf domain
HGR01_23550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGR01_23580	COG2340	Cysteine-rich secretory protein family
HGR01_23635	COG0515	serine threonine protein kinase
HGR01_23635	COG3266	domain, Protein
HGR01_23650	COG0745	RESPONSE REGULATOR receiver
HGR01_23670	COG0783	Belongs to the Dps family
HGR01_23680	COG2385	sporulation resulting in formation of a cellular spore
HGR01_23695	COG0024	Methionine aminopeptidase
HGR01_23730	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HGR01_23765	COG0745	RESPONSE REGULATOR receiver
HGR01_23775	COG1045	serine acetyltransferase
HGR01_23780	COG1959	2 iron, 2 sulfur cluster binding
HGR01_23785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HGR01_23800	COG5002	protein histidine kinase activity
HGR01_23805	COG0784	Response regulator, receiver
HGR01_23810	COG4251	negative regulation of phosphorylation
HGR01_23950	COG0045	succinate-CoA ligase (ADP-forming) activity
HGR01_23955	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
HGR01_23985	COG0438	transferase activity, transferring glycosyl groups
HGR01_24005	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HGR01_24015	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HGR01_24025	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HGR01_24040	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HGR01_24045	COG0489	protein tyrosine kinase activity
HGR01_24055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HGR01_24095	COG2954	triphosphatase activity
HGR01_24100	COG1233	COG1233 Phytoene dehydrogenase and related
HGR01_24105	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HGR01_24125	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HGR01_24160	COG5002	protein histidine kinase activity
HGR01_24165	COG3437	response regulator, receiver
HGR01_24185	COG1192	Involved in chromosome partitioning
HGR01_24190	COG2124	cytochrome p450
HGR01_24210	COG1132	(ABC) transporter
HGR01_24230	COG0488	(ABC) transporter
HGR01_24245	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
HGR01_24265	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
HGR01_24305	COG1819	glycosyl
HGR01_24315	COG0435	Glutathione S-transferase
HGR01_24320	COG0598	Magnesium transport protein CorA
HGR01_24345	COG0714	Associated with various cellular activities
HGR01_24355	COG1305	Transglutaminase-like
HGR01_24405	COG1160	GTP binding
HGR01_24410	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HGR01_24415	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HGR01_24425	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HGR01_24430	COG1799	cell septum assembly
HGR01_24435	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HGR01_24445	COG4581	dead DEAH box helicase
HGR01_24450	COG2119	membrane
HGR01_24500	COG0628	permease
HGR01_24535	COG4279	zinc finger
HGR01_24540	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HGR01_24550	COG0515	serine threonine protein kinase
HGR01_24590	COG0501	Belongs to the peptidase M48B family
HGR01_24600	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
HGR01_24605	COG1012	belongs to the aldehyde dehydrogenase family
HGR01_24615	COG0113	porphobilinogen synthase activity
HGR01_24645	COG0302	gtp cyclohydrolase
HGR01_24650	COG0523	cobalamin synthesis protein
HGR01_24675	COG0531	amino acid
HGR01_24680	COG1120	ATPase activity
HGR01_24685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGR01_24710	COG5001	Diguanylate cyclase
HGR01_24710	COG4251	negative regulation of phosphorylation
HGR01_24710	COG3706	GGDEF domain
HGR01_24710	COG2203	Gaf domain
HGR01_24710	COG3706	GGDEF domain
HGR01_24710	COG2203	Gaf domain
HGR01_24710	COG4251	negative regulation of phosphorylation
HGR01_24710	COG5001	Diguanylate cyclase
HGR01_24760	COG0312	modulator of DNA gyrase
HGR01_24770	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
HGR01_24785	COG0714	Associated with various cellular activities
HGR01_24790	COG0196	riboflavin kinase activity
HGR01_24795	COG1234	tRNA 3'-trailer cleavage
HGR01_24800	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HGR01_24805	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
HGR01_24820	COG0514	ATP-dependent DNA helicase (RecQ)
HGR01_24835	COG3852	Histidine kinase
HGR01_24840	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HGR01_24850	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_24850	COG0515	serine threonine protein kinase
HGR01_24855	COG0477	Major facilitator Superfamily
HGR01_24865	COG2205	protein histidine kinase activity
HGR01_24865	COG0784	Response regulator, receiver
HGR01_24875	COG2304	oxidoreductase activity
HGR01_24905	COG0167	dihydroorotate dehydrogenase activity
HGR01_24920	COG1446	asparaginase
HGR01_24925	COG2319	Wd-40 repeat
HGR01_24930	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HGR01_24935	COG3437	response regulator, receiver
HGR01_24940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HGR01_24940	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HGR01_24955	COG4783	chaperone-mediated protein folding
HGR01_24970	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
HGR01_25035	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGR01_25070	COG2226	methyltransferase
HGR01_25075	COG0745	RESPONSE REGULATOR receiver
HGR01_25085	COG1215	transferase activity, transferring glycosyl groups
HGR01_25095	COG1657	PFAM Prenyltransferase squalene oxidase
HGR01_25110	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
HGR01_25115	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
HGR01_25120	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HGR01_25120	COG0512	Glutamine amidotransferase of anthranilate synthase
HGR01_25135	COG0006	proline dipeptidase activity
HGR01_25140	COG3903	Transcriptional regulator
HGR01_25140	COG3629	intracellular signal transduction
HGR01_25185	COG2205	protein histidine kinase activity
HGR01_25185	COG2202	Pas domain
HGR01_25225	COG2010	Cytochrome c
HGR01_25245	COG0697	spore germination
HGR01_25270	COG0564	pseudouridine synthase activity
HGR01_25275	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HGR01_25295	COG0406	alpha-ribazole phosphatase activity
HGR01_25310	COG3670	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
HGR01_25325	COG0445	tRNA wobble uridine modification
HGR01_25370	COG1695	Transcriptional regulator
HGR01_25375	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
HGR01_25385	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
HGR01_25405	COG2239	Acts as a magnesium transporter
HGR01_25410	COG0540	Belongs to the ATCase OTCase family
HGR01_25415	COG0612	Peptidase, M16
HGR01_25420	COG0612	Peptidase, M16
HGR01_25440	COG0384	phenazine biosynthesis protein PhzF
HGR01_25445	COG0784	Response regulator, receiver
HGR01_25445	COG5002	protein histidine kinase activity
HGR01_25460	COG0006	proline dipeptidase activity
HGR01_25470	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HGR01_25475	COG0228	four-way junction DNA binding
HGR01_25485	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HGR01_25490	COG1702	phosphate starvation-inducible protein PhoH
HGR01_25500	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HGR01_25505	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HGR01_25510	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
HGR01_25515	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
HGR01_25520	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HGR01_25525	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
HGR01_25595	COG0515	serine threonine protein kinase
HGR01_25595	COG2815	serine threonine protein kinase
HGR01_25635	COG3845	ABC transporter
HGR01_25645	COG4178	(ABC) transporter
HGR01_25665	COG0745	RESPONSE REGULATOR receiver
HGR01_25675	COG5000	phosphorelay sensor kinase activity
HGR01_25675	COG5002	protein histidine kinase activity
HGR01_25850	COG5002	protein histidine kinase activity
HGR01_25855	COG0745	RESPONSE REGULATOR receiver
HGR01_25870	COG0489	protein tyrosine kinase activity
HGR01_25870	COG3206	protein involved in exopolysaccharide biosynthesis
HGR01_25875	COG1596	polysaccharide export
HGR01_25910	COG2205	protein histidine kinase activity
HGR01_25910	COG0784	Response regulator, receiver
HGR01_25910	COG2198	Histidine kinase
HGR01_25925	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
HGR01_25930	COG0745	RESPONSE REGULATOR receiver
HGR01_25935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HGR01_25940	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
HGR01_25945	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HGR01_25950	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HGR01_25955	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HGR01_25960	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HGR01_25965	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HGR01_25975	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HGR01_25985	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
HGR01_25990	COG0511	ligase activity, forming carbon-carbon bonds
HGR01_25995	COG0640	Transcriptional regulator
HGR01_26005	COG0442	prolyl-tRNA aminoacylation
HGR01_26045	COG5554	nitrogen fixation
HGR01_26050	COG5554	nitrogen fixation
HGR01_26055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HGR01_26070	COG1045	serine acetyltransferase
HGR01_26110	COG0515	serine threonine protein kinase
HGR01_26110	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_26170	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HGR01_26225	COG1595	DNA-templated transcription, initiation
HGR01_26230	COG0745	RESPONSE REGULATOR receiver
HGR01_26235	COG2205	protein histidine kinase activity
HGR01_26235	COG0784	Response regulator, receiver
HGR01_26290	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HGR01_26290	COG0822	iron-sulfur transferase activity
HGR01_26290	COG2906	2 iron, 2 sulfur cluster binding
HGR01_26300	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
HGR01_26410	COG0582	viral genome integration into host DNA
HGR01_26460	COG1028	Short-chain dehydrogenase reductase Sdr
HGR01_26495	COG0412	Dienelactone hydrolase
HGR01_26555	COG1943	Transposase
HGR01_26565	COG0582	viral genome integration into host DNA
HGR01_26575	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HGR01_26595	COG0628	permease
HGR01_26690	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HGR01_26705	COG5420	small protein containing a coiled-coil domain
HGR01_26715	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HGR01_26720	COG0316	Belongs to the HesB IscA family
HGR01_26735	COG3585	molybdate ion transport
HGR01_26780	COG0556	nucleotide-excision repair
HGR01_26790	COG3237	CsbD-like
HGR01_26820	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HGR01_26835	COG0628	permease
HGR01_26845	COG1316	TRANSCRIPTIONal
HGR01_26860	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HGR01_26870	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HGR01_26870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HGR01_26885	COG2197	response regulator
HGR01_26895	COG2884	Cell division ATP-binding protein ftsE
HGR01_26900	COG3852	Histidine kinase
HGR01_26905	COG2205	protein histidine kinase activity
HGR01_26905	COG0784	Response regulator, receiver
HGR01_26930	COG0601	transmembrane transport
HGR01_26935	COG0747	negative chemotaxis
HGR01_26955	COG0539	negative regulation of cytoplasmic translation
HGR01_26980	COG3850	Histidine kinase
HGR01_26980	COG4999	Histidine kinase
HGR01_26980	COG2205	protein histidine kinase activity
HGR01_26980	COG3437	response regulator, receiver
HGR01_26995	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HGR01_27030	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_27030	COG0515	serine threonine protein kinase
HGR01_27065	COG0539	negative regulation of cytoplasmic translation
HGR01_27070	COG0412	Dienelactone hydrolase
HGR01_27075	COG2188	Transcriptional regulator
HGR01_27095	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
HGR01_27100	COG0740	serine-type endopeptidase activity
HGR01_27105	COG0544	peptidyl-prolyl cis-trans isomerase activity
HGR01_27110	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
HGR01_27115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HGR01_27120	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HGR01_27160	COG0333	Belongs to the bacterial ribosomal protein bL32 family
HGR01_27165	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
HGR01_27170	COG1012	belongs to the aldehyde dehydrogenase family
HGR01_27205	COG0804	urea catabolic process
HGR01_27215	COG0832	Belongs to the urease beta subunit family
HGR01_27220	COG0831	urea catabolic process
HGR01_27225	COG0829	nickel cation binding
HGR01_27230	COG1192	Involved in chromosome partitioning
HGR01_27245	COG0459	protein refolding
HGR01_27250	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
HGR01_27260	COG0745	RESPONSE REGULATOR receiver
HGR01_27265	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
HGR01_27270	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
HGR01_27280	COG0745	RESPONSE REGULATOR receiver
HGR01_27285	COG2203	Gaf domain
HGR01_27285	COG0840	transmembrane signaling receptor activity
HGR01_27295	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_27295	COG0515	serine threonine protein kinase
HGR01_27310	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HGR01_27330	COG1994	Peptidase M50
HGR01_27330	COG0517	IMP dehydrogenase activity
HGR01_27360	COG0305	Participates in initiation and elongation during chromosome replication
HGR01_27360	COG1372	Participates in initiation and elongation during chromosome replication
HGR01_27365	COG0359	binds to the 23S rRNA
HGR01_27375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HGR01_27395	COG1132	(ABC) transporter
HGR01_27435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HGR01_27465	COG1515	deoxyribonuclease V activity
HGR01_27470	COG0330	HflC and HflK could
HGR01_27475	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
HGR01_27480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HGR01_27525	COG3852	Histidine kinase
HGR01_27535	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HGR01_27540	COG2197	response regulator
HGR01_27550	COG4585	Histidine kinase
HGR01_27600	COG2274	protein secretion by the type I secretion system
HGR01_27620	COG1696	Membrane protein involved in D-alanine export
HGR01_27635	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HGR01_27685	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HGR01_27695	COG0643	Histidine kinase
HGR01_27695	COG0784	Response regulator, receiver
HGR01_27695	COG2198	Histidine kinase
HGR01_27700	COG0840	transmembrane signaling receptor activity
HGR01_27700	COG2203	Gaf domain
HGR01_27715	COG0784	Response regulator, receiver
HGR01_27725	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HGR01_27740	COG2062	phosphohistidine phosphatase, SixA
HGR01_27745	COG0372	Belongs to the citrate synthase family
HGR01_27760	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
HGR01_27765	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HGR01_27770	COG0839	Belongs to the complex I subunit 6 family
HGR01_27775	COG0713	ATP synthesis coupled electron transport
HGR01_27780	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HGR01_27790	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HGR01_27850	COG1063	alcohol dehydrogenase
HGR01_27855	COG0129	dihydroxy-acid dehydratase activity
HGR01_27865	COG0601	transmembrane transport
HGR01_27870	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HGR01_27885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HGR01_27895	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
HGR01_27905	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HGR01_27910	COG0573	inorganic phosphate transmembrane transporter activity
HGR01_27915	COG0581	inorganic phosphate transmembrane transporter activity
HGR01_27920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HGR01_27925	COG1201	RNA secondary structure unwinding
HGR01_27970	COG1063	alcohol dehydrogenase
HGR01_27980	COG0438	transferase activity, transferring glycosyl groups
HGR01_27995	COG3185	4-Hydroxyphenylpyruvate dioxygenase
HGR01_28015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HGR01_28020	COG2197	response regulator
HGR01_28030	COG0154	amidase activity
HGR01_28055	COG2814	Major facilitator Superfamily
HGR01_28065	COG4221	oxidoreductase activity
HGR01_28075	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HGR01_28080	COG2873	o-acetylhomoserine
HGR01_28090	COG0751	glycine-tRNA ligase activity
HGR01_28095	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
HGR01_28100	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HGR01_28105	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGR01_28110	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HGR01_28115	COG1120	ATPase activity
HGR01_28130	COG4774	siderophore transport
HGR01_28160	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HGR01_28170	COG2207	Transcriptional regulator
HGR01_28180	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
HGR01_28185	COG1132	(ABC) transporter
HGR01_28220	COG2226	methyltransferase
HGR01_28280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HGR01_28295	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
HGR01_28300	COG1132	(ABC) transporter
HGR01_28305	COG1132	(ABC) transporter
HGR01_28355	COG1464	Belongs to the NlpA lipoprotein family
HGR01_28360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HGR01_28370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HGR01_28375	COG1116	anion transmembrane transporter activity
HGR01_28385	COG0515	serine threonine protein kinase
HGR01_28385	COG2815	serine threonine protein kinase
HGR01_28410	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HGR01_28415	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HGR01_28465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HGR01_28470	COG1819	glycosyl
HGR01_28475	COG1819	glycosyl
HGR01_28490	COG3292	Two component regulator propeller
HGR01_28490	COG2205	protein histidine kinase activity
HGR01_28490	COG0745	RESPONSE REGULATOR receiver
HGR01_28495	COG2201	protein-glutamate methylesterase activity
HGR01_28500	COG0784	Response regulator, receiver
HGR01_28500	COG0643	Histidine kinase
HGR01_28500	COG2198	Histidine kinase
HGR01_28545	COG1672	PFAM Archaeal ATPase
HGR01_28545	COG2319	Wd-40 repeat
HGR01_28575	COG4249	Peptidase C14 caspase catalytic subunit p20
HGR01_28575	COG2319	Wd-40 repeat
HGR01_28595	COG1404	Belongs to the peptidase S8 family
HGR01_28650	COG2319	Wd-40 repeat
HGR01_28650	COG1672	PFAM Archaeal ATPase
HGR01_28655	COG4249	Peptidase C14 caspase catalytic subunit p20
HGR01_28655	COG2319	Wd-40 repeat
HGR01_28660	COG2319	Wd-40 repeat
HGR01_28660	COG4249	Peptidase C14 caspase catalytic subunit p20
HGR01_28695	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HGR01_28705	COG1910	domain protein
HGR01_28715	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HGR01_28720	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HGR01_28730	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
HGR01_28745	COG1271	oxidase subunit
HGR01_28750	COG1294	oxidase, subunit
HGR01_28755	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
HGR01_28765	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGR01_28775	COG1910	domain protein
HGR01_28780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HGR01_28810	COG1122	ATPase activity
HGR01_28825	COG1309	transcriptional regulator
HGR01_28845	COG0778	Nitroreductase
HGR01_28900	COG2319	Wd-40 repeat
HGR01_28900	COG4249	Peptidase C14 caspase catalytic subunit p20
HGR01_29005	COG2197	response regulator
HGR01_29020	COG0443	Heat shock 70 kDa protein
HGR01_29070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HGR01_29120	COG5285	phytanoyl-CoA dioxygenase
HGR01_29185	COG1917	Cupin 2, conserved barrel domain protein
HGR01_29185	COG2207	Transcriptional regulator
HGR01_29235	COG0667	Aldo Keto reductase
HGR01_29245	COG0346	lactoylglutathione lyase activity
HGR01_29305	COG0672	)-iron permease
HGR01_29310	COG2822	iron ion transport
HGR01_29330	COG1845	cytochrome c oxidase, subunit III
HGR01_29340	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HGR01_29365	COG2010	Cytochrome c
HGR01_29380	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HGR01_29380	COG3321	synthase
HGR01_29380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HGR01_29405	COG4771	TonB-dependent receptor
HGR01_29410	COG2807	transmembrane transport
HGR01_29425	COG4585	Histidine kinase
HGR01_29430	COG2197	response regulator
HGR01_29440	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HGR01_29440	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HGR01_29450	COG1266	CAAX protease self-immunity
HGR01_29455	COG1266	CAAX protease self-immunity
HGR01_29475	COG2080	2 iron, 2 sulfur cluster binding
HGR01_29480	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
HGR01_29485	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HGR01_29590	COG3903	Transcriptional regulator
HGR01_29590	COG3629	intracellular signal transduction
HGR01_29600	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HGR01_29650	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HGR01_29655	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
HGR01_29665	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HGR01_29705	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HGR01_29710	COG1121	(ABC) transporter
HGR01_29715	COG3443	Belongs to the bacterial solute-binding protein 9 family
HGR01_29715	COG0803	Belongs to the bacterial solute-binding protein 9 family
HGR01_29720	COG3659	wide pore channel activity
HGR01_29745	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
HGR01_29760	COG0318	PFAM AMP-dependent synthetase and ligase
HGR01_29770	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
HGR01_29775	COG5001	Diguanylate cyclase
HGR01_29775	COG3706	GGDEF domain
HGR01_29775	COG3706	GGDEF domain
HGR01_29775	COG2203	Gaf domain
HGR01_29775	COG5001	Diguanylate cyclase
HGR01_29775	COG4251	negative regulation of phosphorylation
HGR01_29775	COG2203	Gaf domain
HGR01_29775	COG4251	negative regulation of phosphorylation
HGR01_29795	COG1136	(ABC) transporter
HGR01_29800	COG3631	Ketosteroid isomerase-related protein
HGR01_29810	COG0546	phosphoglycolate phosphatase activity
HGR01_29815	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HGR01_29820	COG3631	Ketosteroid isomerase-related protein
HGR01_29830	COG0724	RNA recognition motif
HGR01_29840	COG0724	RNA recognition motif
HGR01_29845	COG3118	belongs to the thioredoxin family
HGR01_29860	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
HGR01_29870	COG0012	GTP binding
HGR01_29895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HGR01_29910	COG0784	Response regulator, receiver
HGR01_29910	COG2205	protein histidine kinase activity
HGR01_29970	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HGR01_29980	COG0784	Response regulator, receiver
HGR01_29980	COG5002	protein histidine kinase activity
HGR01_29990	COG0297	glycogen (starch) synthase activity
HGR01_29995	COG0181	hydroxymethylbilane synthase activity
HGR01_30025	COG1672	PFAM Archaeal ATPase
HGR01_30025	COG2319	Wd-40 repeat
HGR01_30035	COG1803	Methylglyoxal synthase
HGR01_30035	COG1597	lipid kinase activity
HGR01_30055	COG0475	glutathione-regulated potassium exporter activity
HGR01_30100	COG0126	phosphoglycerate kinase activity
HGR01_30105	COG0589	response to stress
HGR01_30120	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HGR01_30130	COG0515	serine threonine protein kinase
HGR01_30130	COG3266	domain, Protein
HGR01_30140	COG0017	Asparaginyl-tRNA synthetase
HGR01_30160	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HGR01_30205	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HGR01_30215	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
HGR01_30230	COG2202	Pas domain
HGR01_30230	COG2205	protein histidine kinase activity
HGR01_30235	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HGR01_30240	COG4251	negative regulation of phosphorylation
HGR01_30250	COG1649	PFAM Uncharacterised BCR, COG1649
HGR01_30260	COG0596	Alpha beta hydrolase
HGR01_30270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HGR01_30275	COG1361	Conserved repeat domain
HGR01_30290	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGR01_30295	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
HGR01_30300	COG0085	RNA polymerase activity
HGR01_30305	COG0084	hydrolase, TatD family'
HGR01_30310	COG0268	Binds directly to 16S ribosomal RNA
HGR01_30315	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HGR01_30320	COG0589	response to stress
HGR01_30330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGR01_30340	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HGR01_30375	COG0612	Peptidase, M16
HGR01_30380	COG3001	Fructosamine kinase
HGR01_30385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HGR01_30390	COG0805	protein transport
HGR01_30400	COG0741	lytic transglycosylase activity
HGR01_30410	COG0784	Response regulator, receiver
HGR01_30410	COG2205	protein histidine kinase activity
HGR01_30415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HGR01_30425	COG0217	transcriptional regulatory protein
HGR01_30480	COG2234	aminopeptidase activity
HGR01_30495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HGR01_30505	COG1132	(ABC) transporter
HGR01_30510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HGR01_30515	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HGR01_30530	COG0390	transport system, permease component
HGR01_30565	COG0515	serine threonine protein kinase
HGR01_30565	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_30570	COG2319	Wd-40 repeat
HGR01_30570	COG3903	Transcriptional regulator
HGR01_30600	COG3311	Transcriptional regulator
HGR01_30605	COG0456	acetyltransferase
HGR01_30610	COG1063	alcohol dehydrogenase
HGR01_30615	COG0306	phosphate transporter
HGR01_30620	COG0697	spore germination
HGR01_30635	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
HGR01_30640	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HGR01_30645	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HGR01_30675	COG1295	ribonuclease BN
HGR01_30700	COG4251	negative regulation of phosphorylation
HGR01_30700	COG5001	Diguanylate cyclase
HGR01_30700	COG3706	GGDEF domain
HGR01_30700	COG2203	Gaf domain
HGR01_30705	COG2205	protein histidine kinase activity
HGR01_30715	COG0438	transferase activity, transferring glycosyl groups
HGR01_30735	COG3240	lipase activity
HGR01_30765	COG1361	Conserved repeat domain
HGR01_30785	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
HGR01_30785	COG3266	domain, Protein
HGR01_30795	COG0195	Participates in both transcription termination and antitermination
HGR01_30800	COG0779	Required for maturation of 30S ribosomal subunits
HGR01_30845	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
HGR01_30875	COG0517	IMP dehydrogenase activity
HGR01_30875	COG0516	GMP reductase activity
HGR01_30880	COG0494	nUDIX hydrolase
HGR01_30890	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGR01_30895	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
HGR01_30900	COG0783	Belongs to the Dps family
HGR01_30935	COG3639	organic phosphonate transmembrane transporter activity
HGR01_30940	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
HGR01_30980	COG0251	oxidation-reduction process
HGR01_30990	COG1640	4-alpha-glucanotransferase
HGR01_30995	COG1426	Protein conserved in bacteria
HGR01_31000	COG1187	pseudouridine synthase activity
HGR01_31010	COG0575	Belongs to the CDS family
HGR01_31020	COG3266	domain, Protein
HGR01_31020	COG0515	serine threonine protein kinase
HGR01_31030	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
HGR01_31035	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGR01_31035	COG0189	ligase activity
HGR01_31040	COG4242	Belongs to the peptidase S51 family
HGR01_31050	COG0336	Belongs to the RNA methyltransferase TrmD family
HGR01_31055	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
HGR01_31070	COG0747	negative chemotaxis
HGR01_31075	COG1691	(AIR) carboxylase
HGR01_31090	COG0165	Argininosuccinate lyase
HGR01_31110	COG0025	NhaP-type Na H and K H
HGR01_31125	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
HGR01_31130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HGR01_31130	COG0426	domain, Protein
HGR01_31135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HGR01_31135	COG0426	domain, Protein
HGR01_31140	COG0724	RNA recognition motif
HGR01_31165	COG0335	large ribosomal subunit rRNA binding
HGR01_31175	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HGR01_31180	COG0250	Participates in transcription elongation, termination and antitermination
HGR01_31185	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
HGR01_31190	COG0081	regulation of translation
HGR01_31195	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
HGR01_31200	COG0222	ribosome binding
HGR01_31220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGR01_31225	COG0431	NADPH-dependent FMN reductase
HGR01_31240	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HGR01_31245	COG4636	protein conserved in cyanobacteria
HGR01_31250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HGR01_31255	COG3956	TIGRFAM MazG family protein
HGR01_31295	COG2070	2-Nitropropane dioxygenase
HGR01_31325	COG0300	oxidoreductase activity
HGR01_31330	COG0440	acetolactate synthase activity
HGR01_31345	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HGR01_31365	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
HGR01_31385	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HGR01_31400	COG0067	glutamate synthase
HGR01_31400	COG0069	glutamate synthase activity
HGR01_31400	COG0070	glutamate synthase
HGR01_31410	COG0662	Cupin 2, conserved barrel domain protein
HGR01_31410	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
HGR01_31420	COG0316	Belongs to the HesB IscA family
HGR01_31425	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
HGR01_31430	COG0049	tRNA binding
HGR01_31435	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HGR01_31440	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
HGR01_31445	COG0051	transcription antitermination factor activity, RNA binding
HGR01_31450	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
HGR01_31455	COG0077	Prephenate dehydratase
HGR01_31465	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HGR01_31470	COG1530	ribonuclease E activity
HGR01_31475	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HGR01_31490	COG0436	Aminotransferase
HGR01_31500	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HGR01_31525	COG2770	Histidine kinase
HGR01_31525	COG3437	response regulator, receiver
HGR01_31550	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HGR01_31555	COG0745	RESPONSE REGULATOR receiver
HGR01_31570	COG3903	Transcriptional regulator
HGR01_31570	COG2319	Wd-40 repeat
HGR01_31595	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HGR01_31595	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HGR01_31625	COG1077	Cell shape determining protein MreB Mrl
HGR01_31650	COG0475	glutathione-regulated potassium exporter activity
HGR01_31655	COG0860	N-Acetylmuramoyl-L-alanine amidase
HGR01_31660	COG0860	N-Acetylmuramoyl-L-alanine amidase
HGR01_31665	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HGR01_31675	COG0142	geranyltranstransferase activity
HGR01_31695	COG1305	Transglutaminase-like
HGR01_31700	COG2052	Domain of unknown function (DUF370)
HGR01_31705	COG0194	GDP metabolic process
HGR01_31725	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
HGR01_31730	COG2267	carboxylic ester hydrolase activity
HGR01_31740	COG0454	-acetyltransferase
HGR01_31755	COG2890	protein-(glutamine-N5) methyltransferase activity
HGR01_31760	COG0009	L-threonylcarbamoyladenylate synthase
HGR01_31765	COG4999	Histidine kinase
HGR01_31765	COG3850	Histidine kinase
HGR01_31765	COG3437	response regulator, receiver
HGR01_31765	COG2205	protein histidine kinase activity
HGR01_31770	COG0454	-acetyltransferase
HGR01_31785	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HGR01_31790	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HGR01_31795	COG0022	dehydrogenase e1 component
HGR01_31795	COG0508	dehydrogenase complex catalyzes the overall conversion of
HGR01_31810	COG0113	porphobilinogen synthase activity
HGR01_31815	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HGR01_31840	COG0745	RESPONSE REGULATOR receiver
HGR01_31845	COG5002	protein histidine kinase activity
HGR01_31850	COG0438	transferase activity, transferring glycosyl groups
HGR01_31870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HGR01_31885	COG1846	Transcriptional regulator
HGR01_31910	COG2897	thiosulfate sulfurtransferase activity
HGR01_31925	COG1649	PFAM Uncharacterised BCR, COG1649
HGR01_31930	COG5001	Diguanylate cyclase
HGR01_31930	COG2203	Gaf domain
HGR01_31930	COG3706	GGDEF domain
HGR01_31930	COG4251	negative regulation of phosphorylation
HGR01_31940	COG2815	serine threonine protein kinase
HGR01_31940	COG0515	serine threonine protein kinase
HGR01_31945	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HGR01_31955	COG0792	nuclease activity
HGR01_31965	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
HGR01_32010	COG0569	domain protein
HGR01_32015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HGR01_32020	COG2226	methyltransferase
HGR01_32025	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HGR01_32040	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HGR01_32045	COG0237	dephospho-CoA kinase activity
HGR01_32060	COG0312	modulator of DNA gyrase
HGR01_32085	COG0484	heat shock protein binding
HGR01_32090	COG0740	serine-type endopeptidase activity
HGR01_32095	COG0740	serine-type endopeptidase activity
HGR01_32100	COG2304	oxidoreductase activity
HGR01_32105	COG2304	oxidoreductase activity
HGR01_32110	COG0346	lactoylglutathione lyase activity
HGR01_32120	COG4956	integral membrane protein (PIN domain superfamily)
HGR01_32125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HGR01_32155	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
HGR01_32180	COG0489	protein tyrosine kinase activity
HGR01_32205	COG0438	transferase activity, transferring glycosyl groups
HGR01_32215	COG0500	methyltransferase
HGR01_32220	COG1215	transferase activity, transferring glycosyl groups
HGR01_32225	COG0562	UDP-galactopyranose mutase
HGR01_32230	COG0463	Glycosyl transferase, family 2
HGR01_32235	COG1216	Glycosyl transferase, family 2
HGR01_32245	COG0438	transferase activity, transferring glycosyl groups
HGR01_32250	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HGR01_32255	COG2244	polysaccharide biosynthetic process
HGR01_32260	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
HGR01_32280	COG0501	Belongs to the peptidase M48B family
HGR01_32285	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HGR01_32295	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HGR01_32310	COG3033	Beta-eliminating lyase
HGR01_32325	COG1598	PFAM Uncharacterised protein family UPF0150
HGR01_32330	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HGR01_32340	COG1253	flavin adenine dinucleotide binding
HGR01_32350	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HGR01_32405	COG5002	protein histidine kinase activity
HGR01_32410	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HGR01_32415	COG2201	protein-glutamate methylesterase activity
HGR01_32435	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HGR01_32450	COG3659	wide pore channel activity
HGR01_32460	COG3237	CsbD-like
HGR01_32470	COG2205	protein histidine kinase activity
HGR01_32470	COG3437	response regulator, receiver
HGR01_32470	COG3850	Histidine kinase
HGR01_32470	COG4999	Histidine kinase
HGR01_32475	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
HGR01_32485	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
HGR01_32500	COG1573	uracil-dna glycosylase
HGR01_32510	COG2501	S4 domain
HGR01_32530	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HGR01_32550	COG5002	protein histidine kinase activity
HGR01_32565	COG1216	Glycosyl transferase, family 2
HGR01_32565	COG1442	glycosyl transferase family 8
HGR01_32570	COG1216	Glycosyl transferase, family 2
HGR01_32570	COG1442	glycosyl transferase family 8
HGR01_32580	COG2244	polysaccharide biosynthetic process
HGR01_32605	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HGR01_32610	COG2198	Histidine kinase
HGR01_32610	COG5002	protein histidine kinase activity
HGR01_32610	COG0784	Response regulator, receiver
HGR01_32640	COG0489	protein tyrosine kinase activity
HGR01_32660	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
HGR01_32685	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HGR01_32705	COG1442	glycosyl transferase family 8
HGR01_32735	COG1216	Glycosyl transferase, family 2
HGR01_32740	COG1216	Glycosyl transferase, family 2
HGR01_32755	COG0275	rRNA processing
HGR01_32770	COG0438	transferase activity, transferring glycosyl groups
HGR01_32775	COG0438	transferase activity, transferring glycosyl groups
HGR01_32780	COG0367	asparagine synthase
HGR01_32800	COG0110	maltose O-acetyltransferase activity
HGR01_32805	COG0438	transferase activity, transferring glycosyl groups
HGR01_32845	COG0463	Glycosyl transferase, family 2
HGR01_32855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HGR01_32865	COG4294	response to UV
HGR01_32870	COG0443	Heat shock 70 kDa protein
HGR01_32885	COG2162	N-hydroxyarylamine O-acetyltransferase activity
HGR01_32930	COG0667	Aldo Keto reductase
HGR01_32960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HGR01_32970	COG0483	inositol monophosphate 1-phosphatase activity
HGR01_32980	COG0484	heat shock protein binding
HGR01_32985	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
HGR01_32990	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HGR01_33005	COG0288	reversible hydration of carbon dioxide
HGR01_33030	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HGR01_33035	COG0134	indole-3-glycerol-phosphate synthase activity
HGR01_33055	COG0745	RESPONSE REGULATOR receiver
HGR01_33060	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HGR01_33065	COG0702	epimerase
HGR01_33075	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
HGR01_33080	COG2205	protein histidine kinase activity
HGR01_33090	COG4251	negative regulation of phosphorylation
HGR01_33095	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
HGR01_33115	COG0525	valine-tRNA ligase activity
HGR01_33140	COG0300	oxidoreductase activity
HGR01_33150	COG0482	sulfurtransferase activity
HGR01_33165	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HGR01_33165	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HGR01_33190	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
HGR01_33220	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HGR01_33245	COG1104	cysteine desulfurase activity
HGR01_33265	COG0481	GTPase activity
HGR01_33275	COG2205	protein histidine kinase activity
HGR01_33275	COG3850	Histidine kinase
HGR01_33275	COG4999	Histidine kinase
HGR01_33275	COG3437	response regulator, receiver
HGR01_33280	COG1803	Methylglyoxal synthase
HGR01_33290	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HGR01_33295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HGR01_33300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGR01_33310	COG2010	Cytochrome c
HGR01_33330	COG2205	protein histidine kinase activity
HGR01_33335	COG0784	Response regulator, receiver
HGR01_33345	COG4771	TonB-dependent receptor
HGR01_33360	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HGR01_33370	COG0697	spore germination
HGR01_33395	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_33395	COG0515	serine threonine protein kinase
HGR01_33405	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HGR01_33415	COG3688	RNA-binding protein containing a PIN domain
HGR01_33420	COG1122	ATPase activity
HGR01_33440	COG2154	pterin-4-alpha-carbinolamine dehydratase
HGR01_33445	COG3659	wide pore channel activity
HGR01_33450	COG1959	2 iron, 2 sulfur cluster binding
HGR01_33455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HGR01_33460	COG0484	heat shock protein binding
HGR01_33475	COG2226	methyltransferase
HGR01_33480	COG1970	mechanosensitive ion channel activity
HGR01_33495	COG0308	aminopeptidase N
HGR01_33500	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
HGR01_33520	COG0572	uridine kinase
HGR01_33525	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HGR01_33530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
HGR01_33535	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
HGR01_33550	COG0598	Magnesium transport protein CorA
HGR01_33565	COG0571	ribonuclease III activity
HGR01_33575	COG0784	Response regulator, receiver
HGR01_33575	COG2205	protein histidine kinase activity
HGR01_33575	COG5002	protein histidine kinase activity
HGR01_33615	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HGR01_33625	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HGR01_33635	COG3852	Histidine kinase
HGR01_33640	COG0515	serine threonine protein kinase
HGR01_33640	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_33655	COG0515	serine threonine protein kinase
HGR01_33655	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_33660	COG1357	PFAM Pentapeptide repeats (8 copies)
HGR01_33660	COG0515	serine threonine protein kinase
HGR01_33680	COG0438	transferase activity, transferring glycosyl groups
HGR01_33700	COG0438	transferase activity, transferring glycosyl groups
HGR01_33705	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HGR01_33710	COG2319	Wd-40 repeat
HGR01_33710	COG4249	Peptidase C14 caspase catalytic subunit p20
HGR01_33730	COG2205	protein histidine kinase activity
HGR01_33730	COG2198	Histidine kinase
HGR01_33730	COG0784	Response regulator, receiver
HGR01_33740	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
HGR01_33760	COG2205	protein histidine kinase activity
HGR01_33765	COG0667	Aldo Keto reductase
HGR01_33770	COG1902	pentaerythritol trinitrate reductase activity
HGR01_33775	COG3266	domain, Protein
HGR01_33775	COG0515	serine threonine protein kinase
HGR01_33785	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HGR01_33800	COG5002	protein histidine kinase activity
HGR01_33810	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HGR01_33820	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HGR01_33830	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
HGR01_33835	COG1131	(ABC) transporter
HGR01_33835	COG0842	Transport permease protein
HGR01_33835	COG1716	ATPase activity
HGR01_33840	COG3266	domain, Protein
HGR01_33840	COG0515	serine threonine protein kinase
HGR01_33855	COG3266	domain, Protein
HGR01_33855	COG0515	serine threonine protein kinase
HGR01_33880	COG3266	domain, Protein
HGR01_33880	COG0515	serine threonine protein kinase
HGR01_33930	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
HGR01_33955	COG0215	cysteine-tRNA ligase activity
HGR01_33960	COG0523	cobalamin synthesis protein
HGR01_33965	COG1490	D-aminoacyl-tRNA deacylase activity
HGR01_33975	COG0521	Mo-molybdopterin cofactor biosynthetic process
HGR01_33980	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HGR01_34000	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
HGR01_34010	COG0039	L-malate dehydrogenase activity
HGR01_34040	COG3409	Peptidoglycan-binding domain 1 protein
HGR01_34040	COG3429	Glucose-6-phosphate dehydrogenase subunit
HGR01_34045	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
HGR01_34050	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HGR01_34055	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HGR01_34060	COG0724	RNA recognition motif
HGR01_34070	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HGR01_34080	COG1045	serine acetyltransferase
HGR01_34090	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HGR01_34100	COG1494	fructose-1,6-bisphosphatase
HGR01_34105	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
HGR01_34115	COG4636	protein conserved in cyanobacteria
HGR01_34125	COG0640	Transcriptional regulator
HGR01_34150	COG0166	Belongs to the GPI family
HGR01_34155	COG0446	pyridine nucleotide-disulphide oxidoreductase
HGR01_34160	COG3852	Histidine kinase
HGR01_34165	COG3631	Ketosteroid isomerase-related protein
HGR01_34185	COG4245	von Willebrand factor, type A
HGR01_34200	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HGR01_34205	COG0579	oxidoreductase
HGR01_34215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HGR01_34220	COG1216	Glycosyl transferase, family 2
HGR01_34245	COG0489	protein tyrosine kinase activity
HGR01_34250	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HGR01_34260	COG1132	(ABC) transporter
HGR01_34265	COG1216	Glycosyl transferase, family 2
HGR01_34265	COG0463	Glycosyl transferase, family 2
HGR01_34285	COG0438	transferase activity, transferring glycosyl groups
HGR01_34335	COG0577	efflux transmembrane transporter activity
HGR01_34335	COG1136	(ABC) transporter
HGR01_34345	COG0739	heme binding
HGR01_34355	COG1376	ErfK ybiS ycfS ynhG family protein
HGR01_34360	COG1595	DNA-templated transcription, initiation
HGR01_34375	COG0495	leucyl-tRNA aminoacylation
HGR01_34395	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
HGR01_34410	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
HGR01_34415	COG4310	Domain of unknown function (DUF2172)
HGR01_34420	COG1619	proteins homologs of microcin C7 resistance protein MccF
HGR01_34470	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HGR01_34480	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HGR01_34505	COG1496	oxidoreductase activity
HGR01_34515	COG0739	heme binding
HGR01_34515	COG0741	lytic transglycosylase activity
HGR01_34515	COG1196	nuclear chromosome segregation
HGR01_34540	COG4636	protein conserved in cyanobacteria
HGR01_34550	COG3659	wide pore channel activity
HGR01_34555	COG0725	ABC transporter, periplasmic molybdate-binding protein
HGR01_34575	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HGR01_34580	COG0725	ABC transporter, periplasmic molybdate-binding protein
HGR01_34655	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
HGR01_34655	COG0758	DNA mediated transformation
HGR01_34705	COG2843	Capsule synthesis protein
HGR01_34710	COG0724	RNA recognition motif
HGR01_34725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HGR01_34725	COG1754	DNA topoisomerase type I activity
HGR01_34730	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HGR01_34740	COG1480	7TM receptor with intracellular HD hydrolase
HGR01_34745	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
HGR01_34760	COG0649	NAD binding
HGR01_34815	COG0275	rRNA processing
HGR01_34825	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HGR01_34835	COG2814	Major facilitator Superfamily
HGR01_34850	COG0745	RESPONSE REGULATOR receiver
HGR01_34870	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HGR01_34875	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HGR01_34880	COG0573	inorganic phosphate transmembrane transporter activity
HGR01_34885	COG0581	inorganic phosphate transmembrane transporter activity
HGR01_34890	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HGR01_34905	COG2204	response regulator
HGR01_34910	COG2226	methyltransferase
HGR01_34915	COG4399	Belongs to the UPF0754 family
HGR01_34925	COG0572	uridine kinase
HGR01_34940	COG1054	Belongs to the UPF0176 family
HGR01_34970	COG5002	protein histidine kinase activity
HGR01_34985	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HGR01_34990	COG2329	Antibiotic biosynthesis monooxygenase
HGR01_35015	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HGR01_35025	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HGR01_35035	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
HGR01_35045	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HGR01_35050	COG3977	Valine--pyruvate aminotransferase
HGR01_35055	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HGR01_35085	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HGR01_35085	COG2022	thiamine diphosphate biosynthetic process
HGR01_35095	COG1981	membrane
HGR01_35105	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
HGR01_35115	COG0612	Peptidase, M16
HGR01_35140	COG1505	serine-type exopeptidase activity
HGR01_35145	COG0784	Response regulator, receiver
HGR01_35145	COG2198	Histidine kinase
HGR01_35145	COG0784	Response regulator, receiver
HGR01_35145	COG0643	Histidine kinase
HGR01_35145	COG0643	Histidine kinase
HGR01_35145	COG2198	Histidine kinase
HGR01_35175	COG0037	tRNA processing
HGR01_35185	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HGR01_35190	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HGR01_35195	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
HGR01_35235	COG0438	transferase activity, transferring glycosyl groups
HGR01_35245	COG1181	Belongs to the D-alanine--D-alanine ligase family
HGR01_35255	COG0583	DNA-binding transcription factor activity
HGR01_35260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HGR01_35270	COG1773	rubredoxin
HGR01_35285	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HGR01_35285	COG0426	domain, Protein
HGR01_35300	COG0426	domain, Protein
HGR01_35300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HGR01_35330	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
HGR01_35355	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
HGR01_35370	COG0436	Aminotransferase
HGR01_35375	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
HGR01_35380	COG2124	cytochrome p450
HGR01_35410	COG3852	Histidine kinase
HGR01_35415	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HGR01_35425	COG1982	Orn Lys Arg decarboxylase major
HGR01_35430	COG0644	oxidoreductase
HGR01_35440	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HGR01_35445	COG1555	photosystem II stabilization
HGR01_35450	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HGR01_35470	COG0515	serine threonine protein kinase
HGR01_35480	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
HGR01_35500	COG4243	Vitamin k epoxide reductase
HGR01_35505	COG0434	BtpA family
HGR01_35510	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
HGR01_35515	COG0513	Belongs to the DEAD box helicase family
HGR01_35555	COG0443	Heat shock 70 kDa protein
HGR01_35560	COG4689	acetoacetate decarboxylase
HGR01_35565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HGR01_35570	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
HGR01_35590	COG0768	penicillin binding
HGR01_35595	COG0802	atpase or kinase
HGR01_35600	COG0391	Required for morphogenesis under gluconeogenic growth conditions
HGR01_35605	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
HGR01_35610	COG0646	methionine synthase
HGR01_35610	COG1410	methionine synthase
HGR01_35625	COG0528	UMP kinase activity
HGR01_35630	COG0233	cytoplasmic translational termination
HGR01_35645	COG0398	Pfam SNARE associated Golgi protein
HGR01_35650	COG0463	Glycosyl transferase, family 2
HGR01_35675	COG0745	RESPONSE REGULATOR receiver
HGR01_35685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGR01_35700	COG1993	acr, cog1993
HGR01_35735	COG0640	Transcriptional regulator
HGR01_35765	COG5002	protein histidine kinase activity
HGR01_35800	COG2226	methyltransferase
HGR01_35830	COG2217	Heavy metal translocating P-type atpase
HGR01_35940	COG2197	response regulator
HGR01_36015	COG0739	heme binding
HGR01_36130	COG2319	Wd-40 repeat
HGR01_36130	COG4249	Peptidase C14 caspase catalytic subunit p20
HGR01_36140	COG4249	Peptidase C14 caspase catalytic subunit p20
HGR01_36140	COG2319	Wd-40 repeat
HGR01_36220	COG4474	Belongs to the UPF0398 family
HGR01_36255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGR01_36370	COG1216	Glycosyl transferase, family 2
HGR01_36370	COG1442	glycosyl transferase family 8
HGR01_36460	COG0592	DNA-directed DNA polymerase activity
HGR01_36465	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HGR01_36490	COG0470	DNA polymerase III
HGR01_36500	COG1132	(ABC) transporter
HGR01_36520	COG1192	Involved in chromosome partitioning
HGR01_36525	COG1475	DNA binding
HGR01_36530	COG5002	protein histidine kinase activity
HGR01_36535	COG0745	RESPONSE REGULATOR receiver
HGR01_36540	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HGR01_36550	COG0589	response to stress
HGR01_36555	COG0398	Pfam SNARE associated Golgi protein
HGR01_36730	COG4680	protein conserved in bacteria
HGR01_36775	COG0542	response to heat
HGR01_36875	COG0515	serine threonine protein kinase
HGR01_36875	COG2815	serine threonine protein kinase
HGR01_36900	COG1192	Involved in chromosome partitioning
HGR01_36905	COG1475	DNA binding
HGR01_36930	COG1372	Participates in initiation and elongation during chromosome replication
HGR01_36930	COG0305	Participates in initiation and elongation during chromosome replication
HGR01_36930	COG1372	Participates in initiation and elongation during chromosome replication
HGR01_36930	COG0305	Participates in initiation and elongation during chromosome replication
HGR01_37030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGR01_37430	COG2274	protein secretion by the type I secretion system
HGR01_37645	COG0582	viral genome integration into host DNA
HGR01_37775	COG1404	Belongs to the peptidase S8 family
HGR01_37885	COG3209	COG3209 Rhs family protein
HGR01_37890	COG4974	Belongs to the 'phage' integrase family
HGR01_37920	COG1819	glycosyl
HGR01_37960	COG0529	Catalyzes the synthesis of activated sulfate
HGR01_37975	COG0604	alcohol dehydrogenase
HGR01_37975	COG3321	synthase
HGR01_37980	COG0604	alcohol dehydrogenase
HGR01_37980	COG3321	synthase
HGR01_38125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HGR01_38155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HGR01_38165	COG1475	DNA binding
HGR01_38285	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HGR01_38300	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
HGR01_38385	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HGR01_38435	COG1475	DNA binding
HGR01_38450	COG1475	DNA binding
HGR01_38455	COG1192	Involved in chromosome partitioning
HGR01_38465	COG1674	ftsk spoiiie
HGR01_38585	COG4974	Belongs to the 'phage' integrase family
HGR01_38590	COG5635	Nacht domain
HGR01_38590	COG2319	Wd-40 repeat
HGR01_38620	COG1475	DNA binding
HGR01_38630	COG0724	RNA recognition motif
HGR01_38635	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HGR01_38655	COG2319	Wd-40 repeat
HGR01_38655	COG4249	Peptidase C14 caspase catalytic subunit p20
HGR01_38705	COG3344	reverse transcriptase
HGR01_38750	COG1487	ribonuclease activity
HGR01_38910	COG1475	DNA binding
HGR01_38915	COG1192	Involved in chromosome partitioning
HGR01_38950	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HGR01_38955	COG0071	Belongs to the small heat shock protein (HSP20) family
HGR01_39030	COG1404	Belongs to the peptidase S8 family
HGR01_39070	COG0582	viral genome integration into host DNA
HGR01_39175	COG1475	DNA binding
HGR01_39225	COG0582	viral genome integration into host DNA
HGR01_39265	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
HGR01_39275	COG1475	DNA binding
HGR01_39410	COG2319	Wd-40 repeat
HGR01_39410	COG4249	Peptidase C14 caspase catalytic subunit p20
HGR01_39425	COG0828	Belongs to the bacterial ribosomal protein bS21 family
HGR01_39430	COG0724	RNA recognition motif
HGR01_39480	COG0582	viral genome integration into host DNA
HGR01_39570	COG4974	Belongs to the 'phage' integrase family
HGR01_39775	COG3591	Belongs to the peptidase S1B family
HGR01_39775	COG1864	DNA RNA non-specific endonuclease
HGR01_39875	COG0582	viral genome integration into host DNA
HGR01_39890	COG1192	Involved in chromosome partitioning
HGR01_39900	COG3903	Transcriptional regulator
HGR01_39900	COG3629	intracellular signal transduction
HGR01_40065	COG1192	Involved in chromosome partitioning
HGR01_40210	COG1192	Involved in chromosome partitioning
HGR01_40260	COG0582	viral genome integration into host DNA
HGR01_40280	COG1695	Transcriptional regulator
HGR01_40360	COG3344	reverse transcriptase
HGR01_40415	COG1192	Involved in chromosome partitioning
HGR01_40440	COG4974	Belongs to the 'phage' integrase family
HGR01_40455	COG0515	serine threonine protein kinase
HGR01_40455	COG3266	domain, Protein