locus-tag	class	description
TREAZ_0008	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TREAZ_0010	COG0552	protein localization to endoplasmic reticulum
TREAZ_0013	COG1136	(ABC) transporter
TREAZ_0015	COG3437	response regulator, receiver
TREAZ_0018	COG4608	Belongs to the ABC transporter superfamily
TREAZ_0019	COG0444	Belongs to the ABC transporter superfamily
TREAZ_0020	COG0601	transmembrane transport
TREAZ_0023	COG1201	RNA secondary structure unwinding
TREAZ_0029	COG1172	Belongs to the binding-protein-dependent transport system permease family
TREAZ_0030	COG1172	Belongs to the binding-protein-dependent transport system permease family
TREAZ_0031	COG1129	ABC transporter
TREAZ_0033	COG1592	Rubrerythrin
TREAZ_0033	COG1773	rubredoxin
TREAZ_0035	COG0735	belongs to the Fur family
TREAZ_0038	COG1045	serine acetyltransferase
TREAZ_0048	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
TREAZ_0051	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
TREAZ_0051	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
TREAZ_0052	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TREAZ_0055	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TREAZ_0056	COG0246	Mannitol dehydrogenase
TREAZ_0059	COG0495	leucyl-tRNA aminoacylation
TREAZ_0061	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
TREAZ_0068	COG1164	Oligoendopeptidase f
TREAZ_0071	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
TREAZ_0073	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TREAZ_0075	COG0720	synthase
TREAZ_0076	COG2078	PFAM AMMECR1 domain protein
TREAZ_0077	COG0758	DNA mediated transformation
TREAZ_0078	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
TREAZ_0079	COG1687	branched-chain amino acid
TREAZ_0080	COG2900	Belongs to the SlyX family
TREAZ_0082	COG0154	amidase activity
TREAZ_0089	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
TREAZ_0092	COG5002	protein histidine kinase activity
TREAZ_0093	COG2204	response regulator
TREAZ_0097	COG2017	converts alpha-aldose to the beta-anomer
TREAZ_0098	COG1390	Produces ATP from ADP in the presence of a proton gradient across the membrane
TREAZ_0100	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TREAZ_0101	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TREAZ_0102	COG1394	ATPase activity, coupled to movement of substances
TREAZ_0103	COG1269	ATP hydrolysis coupled proton transport
TREAZ_0105	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
TREAZ_0109	COG0268	Binds directly to 16S ribosomal RNA
TREAZ_0110	COG0776	regulation of translation
TREAZ_0111	COG0815	Transfers the fatty acyl group on membrane lipoproteins
TREAZ_0114	COG1546	Belongs to the CinA family
TREAZ_0114	COG1058	Belongs to the CinA family
TREAZ_0115	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
TREAZ_0116	COG0254	rRNA binding
TREAZ_0126	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TREAZ_0127	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TREAZ_0132	COG2816	NAD+ diphosphatase activity
TREAZ_0133	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
TREAZ_0133	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
TREAZ_0135	COG0330	HflC and HflK could
TREAZ_0136	COG0330	HflC and HflK could
TREAZ_0138	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TREAZ_0144	COG0346	lactoylglutathione lyase activity
TREAZ_0145	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
TREAZ_0146	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
TREAZ_0149	COG0736	holo-[acyl-carrier-protein] synthase activity
TREAZ_0151	COG0101	tRNA pseudouridine synthase activity
TREAZ_0155	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TREAZ_0157	COG4939	FMN-binding domain protein
TREAZ_0159	COG0246	Mannitol dehydrogenase
TREAZ_0160	COG0673	inositol 2-dehydrogenase activity
TREAZ_0164	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
TREAZ_0168	COG1360	Flagellar Motor Protein
TREAZ_0169	COG1580	Controls the rotational direction of flagella during chemotaxis
TREAZ_0170	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TREAZ_0171	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TREAZ_0171	COG1776	CheC inhibitor of MCP methylation
TREAZ_0174	COG1338	Plays a role in the flagellum-specific transport system
TREAZ_0175	COG1987	bacterial-type flagellum assembly
TREAZ_0176	COG1684	flagellar biosynthetic protein fliR
TREAZ_0177	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
TREAZ_0180	COG0455	bacterial-type flagellum organization
TREAZ_0182	COG1191	sigma factor activity
TREAZ_0188	COG0395	ABC-type sugar transport system, permease component
TREAZ_0190	COG1653	transport
TREAZ_0191	COG0698	ribose 5-phosphate isomerase
TREAZ_0193	COG2376	Dihydroxyacetone kinase
TREAZ_0196	COG1653	transport
TREAZ_0197	COG0395	ABC-type sugar transport system, permease component
TREAZ_0198	COG4209	transmembrane transport
TREAZ_0200	COG0318	PFAM AMP-dependent synthetase and ligase
TREAZ_0207	COG1486	melibiose metabolic process
TREAZ_0210	COG1917	Cupin 2, conserved barrel domain protein
TREAZ_0210	COG2207	Transcriptional regulator
TREAZ_0211	COG1175	transmembrane transport
TREAZ_0212	COG0395	ABC-type sugar transport system, permease component
TREAZ_0219	COG1609	Transcriptional regulator
TREAZ_0221	COG0191	fructose-bisphosphate aldolase activity
TREAZ_0230	COG0673	inositol 2-dehydrogenase activity
TREAZ_0231	COG3962	Belongs to the TPP enzyme family
TREAZ_0232	COG1082	Xylose isomerase domain protein TIM barrel
TREAZ_0235	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
TREAZ_0237	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TREAZ_0238	COG1362	aminopeptidase activity
TREAZ_0239	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
TREAZ_0241	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
TREAZ_0245	COG0708	Exodeoxyribonuclease III
TREAZ_0249	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TREAZ_0254	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TREAZ_0255	COG1104	cysteine desulfurase activity
TREAZ_0256	COG0822	iron-sulfur transferase activity
TREAZ_0256	COG2906	2 iron, 2 sulfur cluster binding
TREAZ_0256	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
TREAZ_0258	COG2226	methyltransferase
TREAZ_0267	COG3328	transposase activity
TREAZ_0275	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TREAZ_0277	COG0617	tRNA 3'-terminal CCA addition
TREAZ_0282	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
TREAZ_0286	COG0564	pseudouridine synthase activity
TREAZ_0290	COG4658	electron transport chain
TREAZ_0293	COG4657	Part of a membrane complex involved in electron transport
TREAZ_0295	COG1449	Belongs to the glycosyl hydrolase 57 family
TREAZ_0296	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TREAZ_0296	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TREAZ_0298	COG4656	Part of a membrane complex involved in electron transport
TREAZ_0311	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TREAZ_0312	COG0587	DNA-directed DNA polymerase activity
TREAZ_0315	COG2801	Transposase and inactivated derivatives
TREAZ_0315	COG3415	Transposase
TREAZ_0317	COG3415	Transposase
TREAZ_0317	COG2801	Transposase and inactivated derivatives
TREAZ_0321	COG0582	viral genome integration into host DNA
TREAZ_0328	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
TREAZ_0329	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
TREAZ_0330	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
TREAZ_0331	COG3437	response regulator, receiver
TREAZ_0331	COG2770	Histidine kinase
TREAZ_0332	COG1214	PFAM Peptidase M22, glycoprotease
TREAZ_0333	COG0802	atpase or kinase
TREAZ_0342	COG0534	Mate efflux family protein
TREAZ_0343	COG2755	lipolytic protein G-D-S-L family
TREAZ_0343	COG0657	acetylesterase activity
TREAZ_0345	COG0431	NADPH-dependent FMN reductase
TREAZ_0345	COG1053	succinate dehydrogenase
TREAZ_0345	COG3976	FMN-binding domain protein
TREAZ_0346	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TREAZ_0352	COG2770	Histidine kinase
TREAZ_0352	COG3437	response regulator, receiver
TREAZ_0353	COG3437	response regulator, receiver
TREAZ_0356	COG0582	viral genome integration into host DNA
TREAZ_0365	COG1192	Involved in chromosome partitioning
TREAZ_0371	COG3655	Transcriptional regulator
TREAZ_0384	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
TREAZ_0401	COG1234	tRNA 3'-trailer cleavage
TREAZ_0402	COG1131	(ABC) transporter
TREAZ_0414	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TREAZ_0416	COG0681	Belongs to the peptidase S26 family
TREAZ_0418	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TREAZ_0422	COG4585	Histidine kinase
TREAZ_0423	COG2197	response regulator
TREAZ_0431	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TREAZ_0431	COG0574	Belongs to the PEP-utilizing enzyme family
TREAZ_0432	COG0667	Aldo Keto reductase
TREAZ_0434	COG1309	transcriptional regulator
TREAZ_0438	COG3842	ATPase activity
TREAZ_0445	COG1122	ATPase activity
TREAZ_0446	COG1268	BioY protein
TREAZ_0450	COG0431	NADPH-dependent FMN reductase
TREAZ_0451	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
TREAZ_0453	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
TREAZ_0454	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
TREAZ_0458	COG0301	tRNA thio-modification
TREAZ_0459	COG1104	cysteine desulfurase activity
TREAZ_0460	COG0640	Transcriptional regulator
TREAZ_0464	COG0371	Dehydrogenase
TREAZ_0465	COG0436	Aminotransferase
TREAZ_0466	COG0124	histidyl-tRNA synthetase
TREAZ_0469	COG2089	acid synthase
TREAZ_0472	COG0217	transcriptional regulatory protein
TREAZ_0473	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
TREAZ_0474	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TREAZ_0477	COG0632	four-way junction helicase activity
TREAZ_0478	COG2255	four-way junction helicase activity
TREAZ_0479	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
TREAZ_0483	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
TREAZ_0484	COG0358	DNA primase activity
TREAZ_0485	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TREAZ_0489	COG1077	Cell shape determining protein MreB Mrl
TREAZ_0490	COG1792	Involved in formation and maintenance of cell shape
TREAZ_0492	COG0768	penicillin binding
TREAZ_0493	COG0772	Belongs to the SEDS family
TREAZ_0495	COG4974	Belongs to the 'phage' integrase family
TREAZ_0496	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TREAZ_0502	COG3328	transposase activity
TREAZ_0507	COG0539	negative regulation of cytoplasmic translation
TREAZ_0512	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
TREAZ_0514	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
TREAZ_0516	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TREAZ_0525	COG1121	(ABC) transporter
TREAZ_0527	COG1490	D-aminoacyl-tRNA deacylase activity
TREAZ_0531	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TREAZ_0533	COG1747	RNA polymerase binding
TREAZ_0533	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TREAZ_0536	COG2207	Transcriptional regulator
TREAZ_0537	COG0343	queuine tRNA-ribosyltransferase activity
TREAZ_0540	COG0756	dUTP diphosphatase activity
TREAZ_0541	COG1185	polyribonucleotide nucleotidyltransferase activity
TREAZ_0542	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TREAZ_0544	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TREAZ_0545	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
TREAZ_0547	COG0779	Required for maturation of 30S ribosomal subunits
TREAZ_0548	COG0840	transmembrane signaling receptor activity
TREAZ_0550	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
TREAZ_0552	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TREAZ_0555	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TREAZ_0559	COG2801	Transposase and inactivated derivatives
TREAZ_0562	COG1126	abc transporter atp-binding protein
TREAZ_0563	COG0765	amino acid transport
TREAZ_0568	COG1643	Atp-dependent helicase
TREAZ_0569	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TREAZ_0570	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TREAZ_0572	COG0251	oxidation-reduction process
TREAZ_0578	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TREAZ_0586	COG1199	ATP-dependent helicase activity
TREAZ_0589	COG4974	Belongs to the 'phage' integrase family
TREAZ_0616	COG0424	maF-like protein
TREAZ_0617	COG0052	Belongs to the universal ribosomal protein uS2 family
TREAZ_0618	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TREAZ_0619	COG0233	cytoplasmic translational termination
TREAZ_0620	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TREAZ_0621	COG0575	Belongs to the CDS family
TREAZ_0622	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TREAZ_0623	COG0750	zinc metalloprotease
TREAZ_0627	COG0305	Participates in initiation and elongation during chromosome replication
TREAZ_0628	COG0359	binds to the 23S rRNA
TREAZ_0630	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
TREAZ_0631	COG0629	single-stranded DNA binding
TREAZ_0632	COG0360	Binds together with S18 to 16S ribosomal RNA
TREAZ_0634	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
TREAZ_0637	COG0820	rRNA (adenine-C2-)-methyltransferase activity
TREAZ_0638	COG4399	Belongs to the UPF0754 family
TREAZ_0644	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
TREAZ_0644	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TREAZ_0646	COG4750	Nucleotidyl transferase
TREAZ_0648	COG3842	ATPase activity
TREAZ_0653	COG2337	Toxic component of a toxin-antitoxin (TA) module
TREAZ_0656	COG0653	protein targeting
TREAZ_0657	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
TREAZ_0661	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
TREAZ_0663	COG2080	2 iron, 2 sulfur cluster binding
TREAZ_0665	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
TREAZ_0668	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
TREAZ_0672	COG1216	Glycosyl transferase, family 2
TREAZ_0675	COG1216	Glycosyl transferase, family 2
TREAZ_0675	COG1442	glycosyl transferase family 8
TREAZ_0676	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
TREAZ_0682	COG0706	membrane insertase activity
TREAZ_0693	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TREAZ_0693	COG1213	nucleotidyl transferase
TREAZ_0699	COG1102	Psort location Cytoplasmic, score
TREAZ_0700	COG1561	YicC-like family, N-terminal region
TREAZ_0701	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TREAZ_0702	COG0564	pseudouridine synthase activity
TREAZ_0703	COG0285	dihydrofolate synthase activity
TREAZ_0707	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
TREAZ_0708	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TREAZ_0718	COG4786	Flagellar basal body rod
TREAZ_0720	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
TREAZ_0721	COG4336	lyase activity
TREAZ_0722	COG1984	allophanate hydrolase subunit 2
TREAZ_0723	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
TREAZ_0735	COG0544	peptidyl-prolyl cis-trans isomerase activity
TREAZ_0736	COG0740	serine-type endopeptidase activity
TREAZ_0737	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
TREAZ_0738	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TREAZ_0739	COG0431	NADPH-dependent FMN reductase
TREAZ_0740	COG0840	transmembrane signaling receptor activity
TREAZ_0744	COG0438	transferase activity, transferring glycosyl groups
TREAZ_0745	COG1486	melibiose metabolic process
TREAZ_0746	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TREAZ_0754	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TREAZ_0755	COG2153	protein acetylation
TREAZ_0758	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
TREAZ_0760	COG1205	dead DEAH box helicase
TREAZ_0760	COG1111	helicase
TREAZ_0768	COG0812	UDP-N-acetylmuramate dehydrogenase activity
TREAZ_0769	COG0215	cysteine-tRNA ligase activity
TREAZ_0770	COG1191	sigma factor activity
TREAZ_0774	COG0528	UMP kinase activity
TREAZ_0775	COG0205	6-phosphofructokinase activity
TREAZ_0779	COG0563	adenylate kinase activity
TREAZ_0793	COG0714	Associated with various cellular activities
TREAZ_0795	COG3552	Protein containing von Willebrand factor type A (VWA) domain
TREAZ_0800	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
TREAZ_0815	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
TREAZ_0817	COG1309	transcriptional regulator
TREAZ_0818	COG3858	chitin binding
TREAZ_0824	COG0497	DNA recombination
TREAZ_0825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TREAZ_0827	COG0835	chemotaxis
TREAZ_0828	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TREAZ_0831	COG1172	Belongs to the binding-protein-dependent transport system permease family
TREAZ_0832	COG1129	ABC transporter
TREAZ_0833	COG1879	ABC-type sugar transport system periplasmic component
TREAZ_0848	COG1543	Belongs to the glycosyl hydrolase 57 family
TREAZ_0850	COG0564	pseudouridine synthase activity
TREAZ_0853	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TREAZ_0853	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TREAZ_0853	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TREAZ_0858	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TREAZ_0859	COG0546	phosphoglycolate phosphatase activity
TREAZ_0861	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TREAZ_0863	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TREAZ_0867	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
TREAZ_0868	COG2885	chlorophyll binding
TREAZ_0874	COG2801	Transposase and inactivated derivatives
TREAZ_0874	COG3415	Transposase
TREAZ_0879	COG2205	protein histidine kinase activity
TREAZ_0879	COG0784	Response regulator, receiver
TREAZ_0879	COG5002	protein histidine kinase activity
TREAZ_0880	COG3437	response regulator, receiver
TREAZ_0882	COG5002	protein histidine kinase activity
TREAZ_0882	COG2205	protein histidine kinase activity
TREAZ_0882	COG0784	Response regulator, receiver
TREAZ_0883	COG3437	response regulator, receiver
TREAZ_0884	COG1335	isochorismatase
TREAZ_0885	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
TREAZ_0886	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TREAZ_0888	COG1157	protein secretion by the type III secretion system
TREAZ_0889	COG1317	bacterial-type flagellum organization
TREAZ_0891	COG1766	The M ring may be actively involved in energy transduction
TREAZ_0892	COG1677	Flagellar hook-basal body complex protein FliE
TREAZ_0895	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
TREAZ_0896	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
TREAZ_0897	COG4974	Belongs to the 'phage' integrase family
TREAZ_0898	COG0551	DNA topoisomerase type I activity
TREAZ_0898	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
TREAZ_0899	COG0758	DNA mediated transformation
TREAZ_0899	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TREAZ_0906	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TREAZ_0907	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
TREAZ_0909	COG0275	rRNA processing
TREAZ_0910	COG2001	Belongs to the MraZ family
TREAZ_0916	COG0191	fructose-bisphosphate aldolase activity
TREAZ_0918	COG0784	Response regulator, receiver
TREAZ_0918	COG2205	protein histidine kinase activity
TREAZ_0919	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
TREAZ_0920	COG0291	Belongs to the bacterial ribosomal protein bL35 family
TREAZ_0921	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TREAZ_0924	COG1671	Belongs to the UPF0178 family
TREAZ_0925	COG3437	response regulator, receiver
TREAZ_0925	COG0784	Response regulator, receiver
TREAZ_0926	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TREAZ_0929	COG0095	Lipoate-protein ligase
TREAZ_0931	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
TREAZ_0933	COG5001	Diguanylate cyclase
TREAZ_0933	COG4251	negative regulation of phosphorylation
TREAZ_0933	COG2203	Gaf domain
TREAZ_0933	COG3706	GGDEF domain
TREAZ_0938	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TREAZ_0939	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
TREAZ_0942	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
TREAZ_0945	COG1131	(ABC) transporter
TREAZ_0946	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TREAZ_0947	COG3942	CHAP domain
TREAZ_0947	COG1388	LysM domain
TREAZ_0949	COG1105	Belongs to the carbohydrate kinase PfkB family
TREAZ_0958	COG0747	negative chemotaxis
TREAZ_0961	COG0444	Belongs to the ABC transporter superfamily
TREAZ_0963	COG2848	UPF0210 protein
TREAZ_0964	COG3830	Belongs to the UPF0237 family
TREAZ_0971	COG0395	ABC-type sugar transport system, permease component
TREAZ_0975	COG0166	Belongs to the GPI family
TREAZ_0976	COG1438	arginine binding
TREAZ_0982	COG1175	transmembrane transport
TREAZ_0983	COG0395	ABC-type sugar transport system, permease component
TREAZ_0987	COG0656	L-ascorbic acid biosynthetic process
TREAZ_0990	COG0673	inositol 2-dehydrogenase activity
TREAZ_0991	COG0395	ABC-type sugar transport system, permease component
TREAZ_0992	COG1175	transmembrane transport
TREAZ_0993	COG1653	transport
TREAZ_0995	COG1070	Carbohydrate kinase
TREAZ_0997	COG1609	Transcriptional regulator
TREAZ_0999	COG1486	melibiose metabolic process
TREAZ_1000	COG1193	negative regulation of DNA recombination
TREAZ_1001	COG1162	GTPase activity
TREAZ_1005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TREAZ_1008	COG1872	DUF167
TREAZ_1010	COG0673	inositol 2-dehydrogenase activity
TREAZ_1011	COG1172	Belongs to the binding-protein-dependent transport system permease family
TREAZ_1012	COG1129	ABC transporter
TREAZ_1013	COG4213	ABC transporter substrate-binding protein
TREAZ_1016	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
TREAZ_1018	COG1940	carbohydrate kinase activity
TREAZ_1047	COG0587	DNA-directed DNA polymerase activity
TREAZ_1050	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
TREAZ_1068	COG2197	response regulator
TREAZ_1076	COG0443	Heat shock 70 kDa protein
TREAZ_1077	COG0443	Heat shock 70 kDa protein
TREAZ_1082	COG0656	L-ascorbic acid biosynthetic process
TREAZ_1083	COG0667	Aldo Keto reductase
TREAZ_1091	COG0739	heme binding
TREAZ_1091	COG1196	nuclear chromosome segregation
TREAZ_1091	COG0741	lytic transglycosylase activity
TREAZ_1094	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
TREAZ_1095	COG1475	DNA binding
TREAZ_1096	COG0784	Response regulator, receiver
TREAZ_1096	COG2205	protein histidine kinase activity
TREAZ_1097	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
TREAZ_1098	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TREAZ_1099	COG0105	UTP biosynthetic process
TREAZ_1100	COG0545	Peptidyl-prolyl cis-trans isomerase
TREAZ_1108	COG1811	Na channel or pump
TREAZ_1109	COG4989	oxidoreductase activity
TREAZ_1112	COG0564	pseudouridine synthase activity
TREAZ_1113	COG1472	Belongs to the glycosyl hydrolase 3 family
TREAZ_1116	COG0534	Mate efflux family protein
TREAZ_1117	COG0534	Mate efflux family protein
TREAZ_1118	COG0017	Asparaginyl-tRNA synthetase
TREAZ_1120	COG1408	metallophosphoesterase
TREAZ_1122	COG0463	Glycosyl transferase, family 2
TREAZ_1149	COG1215	transferase activity, transferring glycosyl groups
TREAZ_1158	COG1028	Short-chain dehydrogenase reductase Sdr
TREAZ_1159	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
TREAZ_1165	COG1120	ATPase activity
TREAZ_1172	COG2132	Multicopper oxidase
TREAZ_1175	COG0157	Belongs to the NadC ModD family
TREAZ_1179	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TREAZ_1185	COG0280	phosphate acetyltransferase
TREAZ_1186	COG0457	Tetratricopeptide repeat
TREAZ_1188	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
TREAZ_1196	COG0601	transmembrane transport
TREAZ_1197	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TREAZ_1198	COG0444	Belongs to the ABC transporter superfamily
TREAZ_1199	COG0444	Belongs to the ABC transporter superfamily
TREAZ_1201	COG0534	Mate efflux family protein
TREAZ_1204	COG0860	N-Acetylmuramoyl-L-alanine amidase
TREAZ_1207	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
TREAZ_1209	COG0731	radical SAM domain protein
TREAZ_1211	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
TREAZ_1212	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
TREAZ_1212	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
TREAZ_1213	COG4942	peptidase
TREAZ_1214	COG0828	Belongs to the bacterial ribosomal protein bS21 family
TREAZ_1219	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
TREAZ_1222	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TREAZ_1223	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TREAZ_1224	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
TREAZ_1225	COG0511	ligase activity, forming carbon-carbon bonds
TREAZ_1226	COG0439	Biotin carboxylase
TREAZ_1227	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
TREAZ_1228	COG0825	malonyl-CoA metabolic process
TREAZ_1231	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
TREAZ_1249	COG0442	prolyl-tRNA aminoacylation
TREAZ_1250	COG3250	beta-galactosidase activity
TREAZ_1258	COG0556	nucleotide-excision repair
TREAZ_1266	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
TREAZ_1268	COG1108	ABC-type Mn2 Zn2 transport systems permease components
TREAZ_1269	COG1489	DNA binding
TREAZ_1274	COG2608	mercury ion transmembrane transporter activity
TREAZ_1279	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TREAZ_1280	COG0765	amino acid transport
TREAZ_1282	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TREAZ_1283	COG0085	RNA polymerase activity
TREAZ_1284	COG0222	ribosome binding
TREAZ_1285	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
TREAZ_1286	COG0081	regulation of translation
TREAZ_1287	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TREAZ_1288	COG0250	Participates in transcription elongation, termination and antitermination
TREAZ_1289	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TREAZ_1291	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TREAZ_1296	COG0835	chemotaxis
TREAZ_1297	COG0643	Histidine kinase
TREAZ_1297	COG2198	Histidine kinase
TREAZ_1299	COG0557	exoribonuclease II activity
TREAZ_1303	COG0527	aspartate kinase activity
TREAZ_1304	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
TREAZ_1306	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TREAZ_1309	COG0436	Aminotransferase
TREAZ_1311	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TREAZ_1312	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
TREAZ_1314	COG0514	ATP-dependent DNA helicase (RecQ)
TREAZ_1316	COG2211	Major facilitator Superfamily
TREAZ_1318	COG0626	cystathionine gamma-synthase activity
TREAZ_1319	COG0626	cystathionine gamma-synthase activity
TREAZ_1320	COG1959	2 iron, 2 sulfur cluster binding
TREAZ_1321	COG1959	2 iron, 2 sulfur cluster binding
TREAZ_1325	COG0411	ABC transporter
TREAZ_1326	COG0410	ABC transporter
TREAZ_1327	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
TREAZ_1331	COG0765	amino acid transport
TREAZ_1337	COG0765	amino acid transport
TREAZ_1338	COG0765	amino acid transport
TREAZ_1339	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TREAZ_1340	COG1126	abc transporter atp-binding protein
TREAZ_1342	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
TREAZ_1343	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TREAZ_1344	COG5000	phosphorelay sensor kinase activity
TREAZ_1345	COG2204	response regulator
TREAZ_1349	COG0475	glutathione-regulated potassium exporter activity
TREAZ_1351	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
TREAZ_1356	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TREAZ_1361	COG1070	Carbohydrate kinase
TREAZ_1362	COG4806	L-rhamnose isomerase
TREAZ_1365	COG0563	adenylate kinase activity
TREAZ_1366	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TREAZ_1367	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TREAZ_1368	COG2201	protein-glutamate methylesterase activity
TREAZ_1371	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
TREAZ_1372	COG0363	glucosamine-6-phosphate deaminase activity
TREAZ_1381	COG1979	alcohol dehydrogenase
TREAZ_1382	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
TREAZ_1382	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
TREAZ_1382	COG0674	pyruvate-flavodoxin oxidoreductase activity
TREAZ_1382	COG1013	pyruvate-flavodoxin oxidoreductase activity
TREAZ_1383	COG3956	TIGRFAM MazG family protein
TREAZ_1387	COG0193	aminoacyl-tRNA hydrolase activity
TREAZ_1388	COG0740	serine-type endopeptidase activity
TREAZ_1389	COG2759	Belongs to the formate--tetrahydrofolate ligase family
TREAZ_1390	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TREAZ_1393	COG0671	phosphoesterase, PA-phosphatase related
TREAZ_1394	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
TREAZ_1395	COG0534	Mate efflux family protein
TREAZ_1397	COG2205	protein histidine kinase activity
TREAZ_1397	COG2198	Histidine kinase
TREAZ_1397	COG0784	Response regulator, receiver
TREAZ_1398	COG0445	tRNA wobble uridine modification
TREAZ_1399	COG0537	adenosine 5'-monophosphoramidase activity
TREAZ_1404	COG0488	(ABC) transporter
TREAZ_1406	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TREAZ_1409	COG3842	ATPase activity
TREAZ_1410	COG1176	ABC-type spermidine putrescine transport system, permease component I
TREAZ_1411	COG1177	transmembrane transport
TREAZ_1414	COG0656	L-ascorbic acid biosynthetic process
TREAZ_1415	COG1063	alcohol dehydrogenase
TREAZ_1419	COG0227	Belongs to the bacterial ribosomal protein bL28 family
TREAZ_1420	COG0321	lipoyl(octanoyl) transferase activity
TREAZ_1420	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
TREAZ_1422	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TREAZ_1424	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TREAZ_1431	COG1028	Short-chain dehydrogenase reductase Sdr
TREAZ_1432	COG0417	DNA replication proofreading
TREAZ_1437	COG0423	glycine-tRNA ligase activity
TREAZ_1438	COG0516	GMP reductase activity
TREAZ_1438	COG0517	IMP dehydrogenase activity
TREAZ_1439	COG1609	Transcriptional regulator
TREAZ_1446	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TREAZ_1448	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
TREAZ_1458	COG0459	protein refolding
TREAZ_1460	COG1528	Iron-storage protein
TREAZ_1461	COG2885	chlorophyll binding
TREAZ_1462	COG1120	ATPase activity
TREAZ_1466	COG4771	TonB-dependent receptor
TREAZ_1471	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
TREAZ_1472	COG0577	efflux transmembrane transporter activity
TREAZ_1472	COG1136	(ABC) transporter
TREAZ_1474	COG1910	domain protein
TREAZ_1478	COG5012	cobalamin binding
TREAZ_1481	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
TREAZ_1482	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TREAZ_1483	COG1116	anion transmembrane transporter activity
TREAZ_1487	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
TREAZ_1491	COG1733	regulation of RNA biosynthetic process
TREAZ_1492	COG3328	transposase activity
TREAZ_1495	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
TREAZ_1497	COG2873	o-acetylhomoserine
TREAZ_1500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TREAZ_1503	COG1929	Belongs to the glycerate kinase type-1 family
TREAZ_1505	COG0584	glycerophosphoryl diester phosphodiesterase
TREAZ_1507	COG0728	peptidoglycan biosynthetic process
TREAZ_1519	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
TREAZ_1523	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
TREAZ_1524	COG2249	NAD(P)H dehydrogenase (quinone) activity
TREAZ_1526	COG0714	Associated with various cellular activities
TREAZ_1533	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
TREAZ_1536	COG1959	2 iron, 2 sulfur cluster binding
TREAZ_1539	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TREAZ_1545	COG0613	PHP domain protein
TREAZ_1547	COG0606	chelatase, subunit chli
TREAZ_1550	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
TREAZ_1551	COG2909	trisaccharide binding
TREAZ_1552	COG2207	Transcriptional regulator
TREAZ_1552	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TREAZ_1553	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TREAZ_1553	COG2207	Transcriptional regulator
TREAZ_1554	COG0513	Belongs to the DEAD box helicase family
TREAZ_1555	COG5012	cobalamin binding
TREAZ_1556	COG3842	ATPase activity
TREAZ_1557	COG1196	nuclear chromosome segregation
TREAZ_1562	COG0210	DNA helicase
TREAZ_1563	COG2239	Acts as a magnesium transporter
TREAZ_1564	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TREAZ_1564	COG0519	Catalyzes the synthesis of GMP from XMP
TREAZ_1565	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
TREAZ_1567	COG0516	GMP reductase activity
TREAZ_1567	COG0517	IMP dehydrogenase activity
TREAZ_1568	COG0165	Argininosuccinate lyase
TREAZ_1572	COG4804	nuclease activity
TREAZ_1577	COG1653	transport
TREAZ_1578	COG0395	ABC-type sugar transport system, permease component
TREAZ_1580	COG1609	Transcriptional regulator
TREAZ_1581	COG0561	phosphatase activity
TREAZ_1583	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
TREAZ_1584	COG0785	Cytochrome C biogenesis protein
TREAZ_1586	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TREAZ_1587	COG0070	glutamate synthase
TREAZ_1587	COG0069	glutamate synthase activity
TREAZ_1587	COG0067	glutamate synthase
TREAZ_1588	COG0791	NLP P60 protein
TREAZ_1590	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
TREAZ_1592	COG0561	phosphatase activity
TREAZ_1593	COG1192	Involved in chromosome partitioning
TREAZ_1594	COG1475	DNA binding
TREAZ_1600	COG1116	anion transmembrane transporter activity
TREAZ_1603	COG0626	cystathionine gamma-synthase activity
TREAZ_1604	COG1045	serine acetyltransferase
TREAZ_1607	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
TREAZ_1608	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TREAZ_1614	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TREAZ_1630	COG0006	proline dipeptidase activity
TREAZ_1631	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
TREAZ_1633	COG3437	response regulator, receiver
TREAZ_1634	COG0784	Response regulator, receiver
TREAZ_1634	COG5002	protein histidine kinase activity
TREAZ_1636	COG1639	'signal transduction protein
TREAZ_1650	COG1151	hydroxylamine reductase activity
TREAZ_1656	COG0395	ABC-type sugar transport system, permease component
TREAZ_1657	COG1175	transmembrane transport
TREAZ_1658	COG1609	Transcriptional regulator
TREAZ_1660	COG1082	Xylose isomerase domain protein TIM barrel
TREAZ_1665	COG2197	response regulator
TREAZ_1676	COG5012	cobalamin binding
TREAZ_1678	COG0322	excinuclease ABC activity
TREAZ_1687	COG0653	protein targeting
TREAZ_1692	COG2217	Heavy metal translocating P-type atpase
TREAZ_1696	COG0534	Mate efflux family protein
TREAZ_1700	COG1160	GTP binding
TREAZ_1701	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TREAZ_1704	COG4953	penicillin-binding protein 1C
TREAZ_1705	COG0668	transmembrane transport
TREAZ_1706	COG2373	Large extracellular alpha-helical protein
TREAZ_1707	COG3328	transposase activity
TREAZ_1718	COG0326	Molecular chaperone. Has ATPase activity
TREAZ_1719	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
TREAZ_1721	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
TREAZ_1722	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TREAZ_1724	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TREAZ_1727	COG0534	Mate efflux family protein
TREAZ_1730	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TREAZ_1732	COG0175	sulfate reduction
TREAZ_1735	COG4208	sulfate ABC transporter
TREAZ_1736	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
TREAZ_1737	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
TREAZ_1740	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
TREAZ_1740	COG1648	precorrin-2 dehydrogenase activity
TREAZ_1742	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
TREAZ_1744	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
TREAZ_1746	COG0724	RNA recognition motif
TREAZ_1750	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TREAZ_1751	COG0823	Involved in the tonB-independent uptake of proteins
TREAZ_1752	COG0071	Belongs to the small heat shock protein (HSP20) family
TREAZ_1768	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
TREAZ_1774	COG0800	Aldolase
TREAZ_1782	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
TREAZ_1784	COG1069	ribulokinase activity
TREAZ_1792	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
TREAZ_1793	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
TREAZ_1794	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
TREAZ_1795	COG1979	alcohol dehydrogenase
TREAZ_1796	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
TREAZ_1801	COG1566	PFAM secretion protein HlyD family protein
TREAZ_1806	COG0673	inositol 2-dehydrogenase activity
TREAZ_1807	COG0280	phosphate acetyltransferase
TREAZ_1809	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TREAZ_1817	COG0318	PFAM AMP-dependent synthetase and ligase
TREAZ_1820	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
TREAZ_1821	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
TREAZ_1821	COG1918	ferrous iron import across plasma membrane
TREAZ_1825	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
TREAZ_1826	COG0784	Response regulator, receiver
TREAZ_1826	COG2205	protein histidine kinase activity
TREAZ_1826	COG5002	protein histidine kinase activity
TREAZ_1830	COG1454	alcohol dehydrogenase
TREAZ_1832	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
TREAZ_1838	COG1609	Transcriptional regulator
TREAZ_1839	COG3250	beta-galactosidase activity
TREAZ_1842	COG0395	ABC-type sugar transport system, permease component
TREAZ_1843	COG1874	Beta-galactosidase
TREAZ_1848	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
TREAZ_1851	COG0784	Response regulator, receiver
TREAZ_1851	COG5002	protein histidine kinase activity
TREAZ_1851	COG2198	Histidine kinase
TREAZ_1854	COG0534	Mate efflux family protein
TREAZ_1855	COG1309	transcriptional regulator
TREAZ_1862	COG0534	Mate efflux family protein
TREAZ_1865	COG4213	ABC transporter substrate-binding protein
TREAZ_1867	COG4214	carbohydrate transport
TREAZ_1869	COG4213	ABC transporter substrate-binding protein
TREAZ_1870	COG0745	RESPONSE REGULATOR receiver
TREAZ_1871	COG2972	Histidine kinase
TREAZ_1873	COG1137	ATPase activity
TREAZ_1878	COG1774	PSP1 C-terminal conserved region
TREAZ_1882	COG0739	heme binding
TREAZ_1886	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TREAZ_1887	COG1127	ABC transporter
TREAZ_1888	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
TREAZ_1890	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TREAZ_1891	COG0673	inositol 2-dehydrogenase activity
TREAZ_1892	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TREAZ_1898	COG0205	6-phosphofructokinase activity
TREAZ_1899	COG0116	Belongs to the methyltransferase superfamily
TREAZ_1902	COG1181	Belongs to the D-alanine--D-alanine ligase family
TREAZ_1903	COG1022	Amp-dependent synthetase and ligase
TREAZ_1911	COG2197	response regulator
TREAZ_1925	COG3415	Transposase
TREAZ_1925	COG2801	Transposase and inactivated derivatives
TREAZ_1927	COG0745	RESPONSE REGULATOR receiver
TREAZ_1966	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
TREAZ_1969	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
TREAZ_1971	COG1349	DNA-binding transcription factor activity
TREAZ_1973	COG1222	aaa ATPase
TREAZ_1984	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
TREAZ_1985	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
TREAZ_1998	COG0246	Mannitol dehydrogenase
TREAZ_1999	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
TREAZ_2000	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
TREAZ_2006	COG1012	belongs to the aldehyde dehydrogenase family
TREAZ_2006	COG1454	alcohol dehydrogenase
TREAZ_2013	COG1129	ABC transporter
TREAZ_2014	COG1172	Belongs to the binding-protein-dependent transport system permease family
TREAZ_2015	COG1879	ABC-type sugar transport system periplasmic component
TREAZ_2018	COG0351	phosphomethylpyrimidine kinase
TREAZ_2022	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
TREAZ_2023	COG2188	Transcriptional regulator
TREAZ_2025	COG3833	ABC-type maltose transport systems, permease component
TREAZ_2026	COG0395	ABC-type sugar transport system, permease component
TREAZ_2030	COG0840	transmembrane signaling receptor activity
TREAZ_2033	COG0784	Response regulator, receiver
TREAZ_2033	COG5002	protein histidine kinase activity
TREAZ_2033	COG2205	protein histidine kinase activity
TREAZ_2035	COG2022	thiamine diphosphate biosynthetic process
TREAZ_2036	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TREAZ_2037	COG0352	thiamine-phosphate diphosphorylase activity
TREAZ_2040	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
TREAZ_2042	COG2205	protein histidine kinase activity
TREAZ_2042	COG0784	Response regulator, receiver
TREAZ_2042	COG5002	protein histidine kinase activity
TREAZ_2045	COG1028	Short-chain dehydrogenase reductase Sdr
TREAZ_2046	COG1272	protein, Hemolysin III
TREAZ_2048	COG0688	phosphatidylethanolamine metabolic process
TREAZ_2049	COG1183	phosphatidylcholine synthase activity
TREAZ_2052	COG2201	protein-glutamate methylesterase activity
TREAZ_2054	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
TREAZ_2055	COG1408	metallophosphoesterase
TREAZ_2057	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TREAZ_2060	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
TREAZ_2062	COG2059	Chromate
TREAZ_2064	COG0066	3-isopropylmalate dehydratase activity
TREAZ_2065	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TREAZ_2066	COG1396	sequence-specific DNA binding
TREAZ_2070	COG0698	ribose 5-phosphate isomerase
TREAZ_2071	COG0395	ABC-type sugar transport system, permease component
TREAZ_2076	COG1609	Transcriptional regulator
TREAZ_2079	COG0714	Associated with various cellular activities
TREAZ_2081	COG1846	Transcriptional regulator
TREAZ_2081	COG1940	carbohydrate kinase activity
TREAZ_2084	COG0395	ABC-type sugar transport system, permease component
TREAZ_2088	COG0714	Associated with various cellular activities
TREAZ_2090	COG0519	Catalyzes the synthesis of GMP from XMP
TREAZ_2092	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
TREAZ_2103	COG5002	protein histidine kinase activity
TREAZ_2104	COG0745	RESPONSE REGULATOR receiver
TREAZ_2106	COG1396	sequence-specific DNA binding
TREAZ_2109	COG1653	transport
TREAZ_2112	COG3842	ATPase activity
TREAZ_2114	COG0395	ABC-type sugar transport system, permease component
TREAZ_2120	COG0667	Aldo Keto reductase
TREAZ_2123	COG1966	Carbon starvation protein
TREAZ_2124	COG0543	2 iron, 2 sulfur cluster binding
TREAZ_2125	COG0167	dihydroorotate dehydrogenase activity
TREAZ_2127	COG3458	cephalosporin-C deacetylase activity
TREAZ_2128	COG2723	6-phospho-beta-galactosidase activity
TREAZ_2130	COG0564	pseudouridine synthase activity
TREAZ_2133	COG0612	Peptidase, M16
TREAZ_2134	COG0534	Mate efflux family protein
TREAZ_2137	COG0784	Response regulator, receiver
TREAZ_2137	COG2205	protein histidine kinase activity
TREAZ_2139	COG1847	R3H domain protein
TREAZ_2140	COG0706	membrane insertase activity
TREAZ_2141	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
TREAZ_2142	COG0594	ribonuclease P activity
TREAZ_2143	COG0230	Belongs to the bacterial ribosomal protein bL34 family
TREAZ_2146	COG3177	Filamentation induced by cAMP protein fic
TREAZ_2149	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
TREAZ_2151	COG2198	Histidine kinase
TREAZ_2151	COG2205	protein histidine kinase activity
TREAZ_2151	COG0784	Response regulator, receiver
TREAZ_2155	COG1373	ATPase (AAA superfamily
TREAZ_2170	COG5002	protein histidine kinase activity
TREAZ_2170	COG2205	protein histidine kinase activity
TREAZ_2170	COG0784	Response regulator, receiver
TREAZ_2177	COG0840	transmembrane signaling receptor activity
TREAZ_2178	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
TREAZ_2180	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TREAZ_2181	COG1652	LysM domain
TREAZ_2190	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
TREAZ_2194	COG0105	UTP biosynthetic process
TREAZ_2195	COG5002	protein histidine kinase activity
TREAZ_2195	COG2198	Histidine kinase
TREAZ_2195	COG0784	Response regulator, receiver
TREAZ_2208	COG0667	Aldo Keto reductase
TREAZ_2211	COG0484	heat shock protein binding
TREAZ_2212	COG0443	Heat shock 70 kDa protein
TREAZ_2213	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TREAZ_2215	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
TREAZ_2215	COG0028	Belongs to the TPP enzyme family
TREAZ_2216	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
TREAZ_2218	COG1968	undecaprenyl-diphosphatase activity
TREAZ_2222	COG1070	Carbohydrate kinase
TREAZ_2223	COG2197	response regulator
TREAZ_2224	COG0084	hydrolase, TatD family'
TREAZ_2225	COG3116	cell division
TREAZ_2225	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
TREAZ_2226	COG3622	Belongs to the hyi family
TREAZ_2229	COG1802	Transcriptional regulator
TREAZ_2232	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
TREAZ_2233	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
TREAZ_2234	COG0840	transmembrane signaling receptor activity
TREAZ_2237	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TREAZ_2238	COG5002	protein histidine kinase activity
TREAZ_2238	COG2205	protein histidine kinase activity
TREAZ_2238	COG0784	Response regulator, receiver
TREAZ_2240	COG0237	dephospho-CoA kinase activity
TREAZ_2241	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
TREAZ_2243	COG0629	single-stranded DNA binding
TREAZ_2245	COG2095	MarC family integral membrane protein
TREAZ_2248	COG3118	belongs to the thioredoxin family
TREAZ_2255	COG4206	TonB-dependent receptor
TREAZ_2257	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TREAZ_2258	COG1120	ATPase activity
TREAZ_2259	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
TREAZ_2260	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
TREAZ_2263	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
TREAZ_2264	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
TREAZ_2266	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TREAZ_2274	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
TREAZ_2276	COG1047	Peptidyl-prolyl cis-trans
TREAZ_2280	COG2610	gluconate transmembrane transporter activity
TREAZ_2283	COG0673	inositol 2-dehydrogenase activity
TREAZ_2284	COG0493	'glutamate synthase
TREAZ_2288	COG1902	pentaerythritol trinitrate reductase activity
TREAZ_2288	COG0446	pyridine nucleotide-disulphide oxidoreductase
TREAZ_2289	COG3328	transposase activity
TREAZ_2290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TREAZ_2297	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
TREAZ_2298	COG0573	inorganic phosphate transmembrane transporter activity
TREAZ_2299	COG0581	inorganic phosphate transmembrane transporter activity
TREAZ_2300	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TREAZ_2304	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
TREAZ_2306	COG1012	belongs to the aldehyde dehydrogenase family
TREAZ_2307	COG4211	Belongs to the binding-protein-dependent transport system permease family
TREAZ_2310	COG3437	response regulator, receiver
TREAZ_2314	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TREAZ_2320	COG1172	Belongs to the binding-protein-dependent transport system permease family
TREAZ_2321	COG1129	ABC transporter
TREAZ_2323	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
TREAZ_2324	COG3275	phosphorelay sensor kinase activity
TREAZ_2327	COG1446	asparaginase
TREAZ_2329	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TREAZ_2336	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
TREAZ_2337	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
TREAZ_2338	COG0592	DNA-directed DNA polymerase activity
TREAZ_2339	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TREAZ_2341	COG0187	DNA topoisomerase II activity
TREAZ_2342	COG1373	ATPase (AAA superfamily
TREAZ_2350	COG2738	Putative neutral zinc metallopeptidase
TREAZ_2351	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
TREAZ_2353	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
TREAZ_2362	COG5002	protein histidine kinase activity
TREAZ_2362	COG2205	protein histidine kinase activity
TREAZ_2362	COG0784	Response regulator, receiver
TREAZ_2374	COG2814	Major facilitator Superfamily
TREAZ_2375	COG0546	phosphoglycolate phosphatase activity
TREAZ_2379	COG1472	Belongs to the glycosyl hydrolase 3 family
TREAZ_2380	COG0492	ferredoxin-NADP+ reductase activity
TREAZ_2382	COG0385	Bile acid
TREAZ_2384	COG1904	glucuronate isomerase
TREAZ_2389	COG1129	ABC transporter
TREAZ_2390	COG1609	Transcriptional regulator
TREAZ_2394	COG2195	Cleaves the N-terminal amino acid of tripeptides
TREAZ_2397	COG1063	alcohol dehydrogenase
TREAZ_2398	COG1994	Peptidase M50
TREAZ_2399	COG2706	6-phosphogluconolactonase activity
TREAZ_2400	COG2084	Dehydrogenase
TREAZ_2408	COG3328	transposase activity
TREAZ_2409	COG3328	transposase activity
TREAZ_2410	COG3328	transposase activity
TREAZ_2411	COG3328	transposase activity
TREAZ_2415	COG4783	chaperone-mediated protein folding
TREAZ_2422	COG0569	domain protein
TREAZ_2423	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
TREAZ_2424	COG5002	protein histidine kinase activity
TREAZ_2424	COG2205	protein histidine kinase activity
TREAZ_2424	COG0784	Response regulator, receiver
TREAZ_2426	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
TREAZ_2435	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
TREAZ_2436	COG3437	response regulator, receiver
TREAZ_2442	COG0643	Histidine kinase
TREAZ_2442	COG2198	Histidine kinase
TREAZ_2453	COG1418	mRNA catabolic process
TREAZ_2454	COG1692	metallophosphoesterase
TREAZ_2456	COG3328	transposase activity
TREAZ_2459	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TREAZ_2460	COG1640	4-alpha-glucanotransferase
TREAZ_2465	COG0228	four-way junction DNA binding
TREAZ_2467	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
TREAZ_2468	COG0336	Belongs to the RNA methyltransferase TrmD family
TREAZ_2469	COG0335	large ribosomal subunit rRNA binding
TREAZ_2473	COG0792	nuclease activity
TREAZ_2475	COG3706	GGDEF domain
TREAZ_2476	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TREAZ_2477	COG1854	S-ribosylhomocysteine lyase activity
TREAZ_2507	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TREAZ_2516	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TREAZ_2517	COG0646	methionine synthase
TREAZ_2517	COG1410	methionine synthase
TREAZ_2523	COG0616	signal peptide processing
TREAZ_2525	COG2339	peptidase activity
TREAZ_2527	COG2207	Transcriptional regulator
TREAZ_2527	COG4753	response regulator
TREAZ_2528	COG1373	ATPase (AAA superfamily
TREAZ_2529	COG2972	Histidine kinase
TREAZ_2536	COG0673	inositol 2-dehydrogenase activity
TREAZ_2537	COG0445	tRNA wobble uridine modification
TREAZ_2538	COG3069	C4-dicarboxylate transmembrane transporter activity
TREAZ_2540	COG1253	flavin adenine dinucleotide binding
TREAZ_2541	COG0151	Belongs to the GarS family
TREAZ_2542	COG0138	bifunctional purine biosynthesis protein purh
TREAZ_2543	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
TREAZ_2544	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
TREAZ_2545	COG0395	ABC-type sugar transport system, permease component
TREAZ_2546	COG0561	phosphatase activity
TREAZ_2547	COG1175	transmembrane transport
TREAZ_2550	COG2942	2-epimerase
TREAZ_2553	COG1484	DNA-dependent DNA replication
TREAZ_2555	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
TREAZ_2557	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
TREAZ_2560	COG1882	Formate acetyltransferase
TREAZ_2573	COG4753	response regulator
TREAZ_2573	COG2207	Transcriptional regulator
TREAZ_2574	COG0395	ABC-type sugar transport system, permease component
TREAZ_2575	COG4209	transmembrane transport
TREAZ_2577	COG3345	alpha-galactosidase
TREAZ_2578	COG2972	Histidine kinase
TREAZ_2579	COG0357	Ribosomal RNA small subunit methyltransferase G
TREAZ_2580	COG1132	(ABC) transporter
TREAZ_2581	COG1132	(ABC) transporter
TREAZ_2582	COG0840	transmembrane signaling receptor activity
TREAZ_2585	COG1846	Transcriptional regulator
TREAZ_2587	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
TREAZ_2590	COG2816	NAD+ diphosphatase activity
TREAZ_2592	COG2183	response to ionizing radiation
TREAZ_2597	COG3328	transposase activity
TREAZ_2598	COG0484	heat shock protein binding
TREAZ_2600	COG0484	heat shock protein binding
TREAZ_2604	COG1028	Short-chain dehydrogenase reductase Sdr
TREAZ_2605	COG0383	alpha-mannosidase activity
TREAZ_2614	COG0072	phenylalanine-tRNA ligase activity
TREAZ_2615	COG1074	ATP-dependent DNA helicase activity
TREAZ_2616	COG0534	Mate efflux family protein
TREAZ_2617	COG2887	Belongs to the helicase family. UvrD subfamily
TREAZ_2618	COG4656	Part of a membrane complex involved in electron transport
TREAZ_2619	COG4658	electron transport chain
TREAZ_2620	COG4659	FMN binding
TREAZ_2621	COG4660	Part of a membrane complex involved in electron transport
TREAZ_2622	COG4657	Part of a membrane complex involved in electron transport
TREAZ_2623	COG1245	4Fe-4S binding domain
TREAZ_2623	COG2878	Part of a membrane complex involved in electron transport
TREAZ_2625	COG1653	transport
TREAZ_2626	COG1175	transmembrane transport
TREAZ_2627	COG0395	ABC-type sugar transport system, permease component
TREAZ_2629	COG3959	Transketolase, thiamine diphosphate binding domain
TREAZ_2630	COG3958	Transketolase
TREAZ_2631	COG2084	Dehydrogenase
TREAZ_2637	COG0673	inositol 2-dehydrogenase activity
TREAZ_2638	COG1063	alcohol dehydrogenase
TREAZ_2641	COG3706	GGDEF domain
TREAZ_2641	COG0745	RESPONSE REGULATOR receiver
TREAZ_2645	COG0395	ABC-type sugar transport system, permease component
TREAZ_2646	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
TREAZ_2647	COG0049	tRNA binding
TREAZ_2649	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
TREAZ_2650	COG0051	transcription antitermination factor activity, RNA binding
TREAZ_2651	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TREAZ_2652	COG0088	Forms part of the polypeptide exit tunnel
TREAZ_2653	COG0089	rRNA binding
TREAZ_2654	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TREAZ_2655	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
TREAZ_2656	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
TREAZ_2657	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TREAZ_2658	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TREAZ_2659	COG0255	Belongs to the universal ribosomal protein uL29 family
TREAZ_2660	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TREAZ_2661	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TREAZ_2662	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
TREAZ_2663	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TREAZ_2665	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TREAZ_2666	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
TREAZ_2667	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
TREAZ_2668	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TREAZ_2669	COG1841	ribosomal large subunit assembly
TREAZ_2670	COG0200	Binds to the 23S rRNA
TREAZ_2671	COG0201	protein transport
TREAZ_2672	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TREAZ_2673	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TREAZ_2674	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TREAZ_2675	COG0202	RNA polymerase activity
TREAZ_2676	COG0203	ribosomal protein L17
TREAZ_2679	COG2843	Capsule synthesis protein
TREAZ_2681	COG2890	protein-(glutamine-N5) methyltransferase activity
TREAZ_2682	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TREAZ_2687	COG3328	transposase activity
TREAZ_2692	COG0488	(ABC) transporter
TREAZ_2693	COG0513	Belongs to the DEAD box helicase family
TREAZ_2694	COG1030	water channel activity
TREAZ_2695	COG4864	UPF0365 protein
TREAZ_2703	COG1842	Phage shock protein A
TREAZ_2706	COG1028	Short-chain dehydrogenase reductase Sdr
TREAZ_2710	COG0793	Belongs to the peptidase S41A family
TREAZ_2713	COG5492	domain, Protein
TREAZ_2715	COG3693	PFAM glycoside hydrolase, family 10
TREAZ_2717	COG3693	PFAM glycoside hydrolase, family 10
TREAZ_2720	COG0455	bacterial-type flagellum organization
TREAZ_2722	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
TREAZ_2723	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
TREAZ_2724	COG3012	SEC-C Motif Domain Protein
TREAZ_2725	COG0281	malic enzyme
TREAZ_2726	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TREAZ_2726	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
TREAZ_2726	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TREAZ_2729	COG1956	GAF domain-containing protein
TREAZ_2730	COG1373	ATPase (AAA superfamily
TREAZ_2738	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TREAZ_2746	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TREAZ_2748	COG1131	(ABC) transporter
TREAZ_2753	COG1940	carbohydrate kinase activity
TREAZ_2762	COG0395	ABC-type sugar transport system, permease component
TREAZ_2763	COG1175	transmembrane transport
TREAZ_2764	COG1609	Transcriptional regulator
TREAZ_2769	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TREAZ_2770	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TREAZ_2771	COG2137	regulation of response to DNA damage stimulus
TREAZ_2773	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
TREAZ_2774	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TREAZ_2775	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
TREAZ_2778	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TREAZ_2781	COG1385	rRNA (uridine-N3-)-methyltransferase activity
TREAZ_2783	COG2204	response regulator
TREAZ_2784	COG4191	Histidine kinase
TREAZ_2786	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TREAZ_2787	COG0561	phosphatase activity
TREAZ_2790	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
TREAZ_2809	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
TREAZ_2826	COG1136	(ABC) transporter
TREAZ_2830	COG3470	protein probably involved in high-affinity Fe2 transport
TREAZ_2831	COG0672	)-iron permease
TREAZ_2833	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TREAZ_2834	COG0659	secondary active sulfate transmembrane transporter activity
TREAZ_2837	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
TREAZ_2839	COG0142	geranyltranstransferase activity
TREAZ_2841	COG0741	lytic transglycosylase activity
TREAZ_2841	COG1196	nuclear chromosome segregation
TREAZ_2841	COG0739	heme binding
TREAZ_2843	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TREAZ_2846	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
TREAZ_2846	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
TREAZ_2847	COG0355	proton-transporting ATP synthase activity, rotational mechanism
TREAZ_2850	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
TREAZ_2851	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TREAZ_2852	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
TREAZ_2853	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TREAZ_2854	COG0356	it plays a direct role in the translocation of protons across the membrane
TREAZ_2856	COG3706	GGDEF domain
TREAZ_2856	COG0745	RESPONSE REGULATOR receiver
TREAZ_2857	COG1674	ftsk spoiiie
TREAZ_2868	COG0420	3'-5' exonuclease activity
TREAZ_2870	COG0419	ATPase involved in DNA repair
TREAZ_2873	COG4977	sequence-specific DNA binding
TREAZ_2873	COG1917	Cupin 2, conserved barrel domain protein
TREAZ_2874	COG0148	phosphopyruvate hydratase activity
TREAZ_2879	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
TREAZ_2880	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
TREAZ_2886	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
TREAZ_2887	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
TREAZ_2888	COG1063	alcohol dehydrogenase
TREAZ_2889	COG1063	alcohol dehydrogenase
TREAZ_2891	COG1940	carbohydrate kinase activity
TREAZ_2895	COG0395	ABC-type sugar transport system, permease component
TREAZ_2896	COG1175	transmembrane transport
TREAZ_2898	COG1063	alcohol dehydrogenase
TREAZ_2902	COG5002	protein histidine kinase activity
TREAZ_2902	COG2205	protein histidine kinase activity
TREAZ_2902	COG0784	Response regulator, receiver
TREAZ_2903	COG0196	riboflavin kinase activity
TREAZ_2905	COG1252	NADH dehydrogenase
TREAZ_2912	COG0701	Predicted permease
TREAZ_2916	COG3976	FMN-binding domain protein
TREAZ_2916	COG1053	succinate dehydrogenase
TREAZ_2923	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TREAZ_2926	COG0163	prenyltransferase activity
TREAZ_2927	COG0109	protoheme IX farnesyltransferase activity
TREAZ_2928	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TREAZ_2929	COG1477	protein flavinylation
TREAZ_2943	COG0084	hydrolase, TatD family'
TREAZ_2944	COG0037	tRNA processing
TREAZ_2945	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
TREAZ_2946	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TREAZ_2947	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
TREAZ_2949	COG0404	The glycine cleavage system catalyzes the degradation of glycine
TREAZ_2952	COG4783	chaperone-mediated protein folding
TREAZ_2956	COG0004	ammonium transporteR
TREAZ_2960	COG1484	DNA-dependent DNA replication
TREAZ_2964	COG4120	Belongs to the binding-protein-dependent transport system permease family
TREAZ_2965	COG1122	ATPase activity
TREAZ_2969	COG1175	transmembrane transport
TREAZ_2970	COG0395	ABC-type sugar transport system, permease component
TREAZ_2971	COG1132	(ABC) transporter
TREAZ_2975	COG1027	Aspartate ammonia-lyase
TREAZ_2979	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TREAZ_2981	COG0784	Response regulator, receiver
TREAZ_2981	COG5002	protein histidine kinase activity
TREAZ_2981	COG2198	Histidine kinase
TREAZ_2982	COG1592	Rubrerythrin
TREAZ_2983	COG2197	response regulator
TREAZ_2992	COG1472	Belongs to the glycosyl hydrolase 3 family
TREAZ_2997	COG1215	transferase activity, transferring glycosyl groups
TREAZ_3003	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
TREAZ_3004	COG1177	transmembrane transport
TREAZ_3005	COG1176	ABC-type spermidine putrescine transport system, permease component I
TREAZ_3006	COG3842	ATPase activity
TREAZ_3009	COG0352	thiamine-phosphate diphosphorylase activity
TREAZ_3011	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TREAZ_3014	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
TREAZ_3016	COG0789	Transcriptional regulator
TREAZ_3018	COG0598	Magnesium transport protein CorA
TREAZ_3019	COG0009	L-threonylcarbamoyladenylate synthase
TREAZ_3023	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
TREAZ_3024	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
TREAZ_3025	COG0440	acetolactate synthase activity
TREAZ_3026	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
TREAZ_3028	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TREAZ_3029	COG0473	3-isopropylmalate dehydrogenase activity
TREAZ_3032	COG1063	alcohol dehydrogenase
TREAZ_3034	COG0318	PFAM AMP-dependent synthetase and ligase
TREAZ_3035	COG0564	pseudouridine synthase activity
TREAZ_3040	COG1091	dTDP-4-dehydrorhamnose reductase activity
TREAZ_3044	COG1373	ATPase (AAA superfamily
TREAZ_3053	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TREAZ_3057	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TREAZ_3079	COG0542	response to heat
TREAZ_3080	COG0823	Involved in the tonB-independent uptake of proteins
TREAZ_3085	COG4154	Belongs to the RbsD FucU family
TREAZ_3088	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
TREAZ_3091	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
TREAZ_3094	COG1464	Belongs to the NlpA lipoprotein family
TREAZ_3095	COG2011	ABC-type metal ion transport system permease component
TREAZ_3096	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TREAZ_3097	COG3437	response regulator, receiver
TREAZ_3098	COG2198	Histidine kinase
TREAZ_3098	COG0784	Response regulator, receiver
TREAZ_3098	COG5002	protein histidine kinase activity
TREAZ_3099	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TREAZ_3101	COG0587	DNA-directed DNA polymerase activity
TREAZ_3105	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TREAZ_3107	COG1063	alcohol dehydrogenase
TREAZ_3111	COG3534	alpha-L-arabinofuranosidase
TREAZ_3113	COG0601	transmembrane transport
TREAZ_3114	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TREAZ_3115	COG0444	Belongs to the ABC transporter superfamily
TREAZ_3116	COG4608	Belongs to the ABC transporter superfamily
TREAZ_3117	COG3534	alpha-L-arabinofuranosidase
TREAZ_3124	COG0673	inositol 2-dehydrogenase activity
TREAZ_3131	COG0488	(ABC) transporter
TREAZ_3132	COG1272	protein, Hemolysin III
TREAZ_3133	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
TREAZ_3140	COG0673	inositol 2-dehydrogenase activity
TREAZ_3144	COG2205	protein histidine kinase activity
TREAZ_3144	COG5002	protein histidine kinase activity
TREAZ_3144	COG0784	Response regulator, receiver
TREAZ_3146	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
TREAZ_3147	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TREAZ_3148	COG0693	protein deglycase activity
TREAZ_3149	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
TREAZ_3149	COG0662	Cupin 2, conserved barrel domain protein
TREAZ_3150	COG0242	peptide deformylase activity
TREAZ_3151	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
TREAZ_3158	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TREAZ_3159	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
TREAZ_3161	COG1132	(ABC) transporter
TREAZ_3162	COG1132	(ABC) transporter
TREAZ_3164	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TREAZ_3169	COG0372	Belongs to the citrate synthase family
TREAZ_3170	COG3550	peptidyl-serine autophosphorylation
TREAZ_3172	COG1396	sequence-specific DNA binding
TREAZ_3173	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
TREAZ_3176	COG0534	Mate efflux family protein
TREAZ_3183	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TREAZ_3184	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TREAZ_3194	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TREAZ_3200	COG0626	cystathionine gamma-synthase activity
TREAZ_3204	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TREAZ_3205	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TREAZ_3206	COG2011	ABC-type metal ion transport system permease component
TREAZ_3207	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TREAZ_3207	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
TREAZ_3208	COG1329	Transcriptional regulator
TREAZ_3209	COG4166	transmembrane transport
TREAZ_3214	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
TREAZ_3215	COG0347	Belongs to the P(II) protein family
TREAZ_3216	COG0347	Belongs to the P(II) protein family
TREAZ_3221	COG0535	radical SAM domain protein
TREAZ_3221	COG1433	Dinitrogenase iron-molybdenum cofactor
TREAZ_3223	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TREAZ_3225	COG3585	molybdate ion transport
TREAZ_3229	COG0725	ABC transporter, periplasmic molybdate-binding protein
TREAZ_3230	COG1910	domain protein
TREAZ_3231	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TREAZ_3232	COG0131	Imidazoleglycerol-phosphate dehydratase
TREAZ_3234	COG0107	imidazoleglycerol-phosphate synthase activity
TREAZ_3235	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TREAZ_3235	COG0140	phosphoribosyl-ATP diphosphatase activity
TREAZ_3236	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TREAZ_3237	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TREAZ_3238	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
TREAZ_3239	COG0318	PFAM AMP-dependent synthetase and ligase
TREAZ_3254	COG2252	PERMEase
TREAZ_3258	COG0673	inositol 2-dehydrogenase activity
TREAZ_3259	COG0395	ABC-type sugar transport system, permease component
TREAZ_3260	COG4209	transmembrane transport
TREAZ_3261	COG1653	transport
TREAZ_3265	COG0673	inositol 2-dehydrogenase activity
TREAZ_3270	COG1692	metallophosphoesterase
TREAZ_3274	COG0784	Response regulator, receiver
TREAZ_3274	COG2198	Histidine kinase
TREAZ_3274	COG5002	protein histidine kinase activity
TREAZ_3306	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TREAZ_3320	COG1413	lyase activity
TREAZ_3322	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TREAZ_3323	COG0333	Belongs to the bacterial ribosomal protein bL32 family
TREAZ_3324	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TREAZ_3325	COG0571	ribonuclease III activity
TREAZ_3326	COG0617	tRNA 3'-terminal CCA addition
TREAZ_3328	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TREAZ_3329	COG1469	GTP cyclohydrolase I activity
TREAZ_3331	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TREAZ_3341	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TREAZ_3342	COG5002	protein histidine kinase activity
TREAZ_3342	COG0784	Response regulator, receiver
TREAZ_3342	COG2198	Histidine kinase
TREAZ_3348	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
TREAZ_3349	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TREAZ_3350	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TREAZ_3351	COG2826	transposase and inactivated derivatives, IS30 family
TREAZ_3355	COG4555	ABC transporter
TREAZ_3358	COG1760	l-serine dehydratase
TREAZ_3359	COG1760	l-serine dehydratase
TREAZ_3360	COG0137	argininosuccinate synthase activity
TREAZ_3361	COG0165	Argininosuccinate lyase
TREAZ_3365	COG1127	ABC transporter
TREAZ_3376	COG1862	Preprotein translocase
TREAZ_3377	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TREAZ_3378	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TREAZ_3379	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TREAZ_3380	COG0525	valine-tRNA ligase activity
TREAZ_3382	COG0534	Mate efflux family protein
TREAZ_3383	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TREAZ_3384	COG0126	phosphoglycerate kinase activity
TREAZ_3384	COG0149	triose-phosphate isomerase activity
TREAZ_3385	COG2205	protein histidine kinase activity
TREAZ_3385	COG0784	Response regulator, receiver
TREAZ_3387	COG0559	Belongs to the binding-protein-dependent transport system permease family
TREAZ_3389	COG0411	ABC transporter
TREAZ_3392	COG1940	carbohydrate kinase activity
TREAZ_3397	COG0517	IMP dehydrogenase activity
TREAZ_3398	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TREAZ_3399	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
TREAZ_3402	COG1269	ATP hydrolysis coupled proton transport
TREAZ_3402	COG1269	ATP hydrolysis coupled proton transport
TREAZ_3406	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
TREAZ_3407	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
TREAZ_3415	COG1394	ATPase activity, coupled to movement of substances
TREAZ_3418	COG0484	heat shock protein binding
TREAZ_3419	COG0024	Methionine aminopeptidase
TREAZ_3421	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TREAZ_3424	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
TREAZ_3425	COG1722	exodeoxyribonuclease VII activity
TREAZ_3426	COG1570	exodeoxyribonuclease VII activity
TREAZ_3430	COG0534	Mate efflux family protein
TREAZ_3431	COG2169	Transcriptional regulator
TREAZ_3434	COG1063	alcohol dehydrogenase
TREAZ_3435	COG1028	Short-chain dehydrogenase reductase Sdr
TREAZ_3435	COG3347	Dehydrogenase
TREAZ_3437	COG0022	dehydrogenase e1 component
TREAZ_3438	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TREAZ_3440	COG1349	DNA-binding transcription factor activity
TREAZ_3441	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TREAZ_3445	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
TREAZ_3447	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TREAZ_3449	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TREAZ_3452	COG0205	6-phosphofructokinase activity
TREAZ_3457	COG0714	Associated with various cellular activities
TREAZ_3463	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TREAZ_3466	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TREAZ_3467	COG1028	Short-chain dehydrogenase reductase Sdr
TREAZ_3468	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
TREAZ_3469	COG0438	transferase activity, transferring glycosyl groups
TREAZ_3470	COG1476	TRANSCRIPTIONal
TREAZ_3480	COG0018	arginyl-trna synthetase
TREAZ_3481	COG2207	Transcriptional regulator
TREAZ_3482	COG0444	Belongs to the ABC transporter superfamily
TREAZ_3483	COG0747	negative chemotaxis
TREAZ_3484	COG0601	transmembrane transport
TREAZ_3485	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TREAZ_3486	COG4608	Belongs to the ABC transporter superfamily
TREAZ_3488	COG1486	melibiose metabolic process
TREAZ_3493	COG0261	This protein binds to 23S rRNA in the presence of protein L20
TREAZ_3495	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TREAZ_3496	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TREAZ_3497	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TREAZ_3501	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
TREAZ_3504	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
TREAZ_3505	COG0037	tRNA processing
TREAZ_3508	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TREAZ_3510	COG0481	GTPase activity
TREAZ_3521	COG1966	Carbon starvation protein
TREAZ_3522	COG0372	Belongs to the citrate synthase family
TREAZ_3524	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TREAZ_3525	COG0444	Belongs to the ABC transporter superfamily
TREAZ_3526	COG4608	Belongs to the ABC transporter superfamily
TREAZ_3527	COG0747	negative chemotaxis
TREAZ_3528	COG1362	aminopeptidase activity
TREAZ_3538	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
TREAZ_3541	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
TREAZ_3543	COG1477	protein flavinylation
TREAZ_3543	COG0457	Tetratricopeptide repeat
TREAZ_3548	COG2003	Belongs to the UPF0758 family
TREAZ_3549	COG1464	Belongs to the NlpA lipoprotein family
TREAZ_3550	COG2011	ABC-type metal ion transport system permease component
TREAZ_3551	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
TREAZ_3557	COG1744	ABC transporter substrate-binding protein PnrA-like
TREAZ_3559	COG4608	Belongs to the ABC transporter superfamily
TREAZ_3560	COG0444	Belongs to the ABC transporter superfamily
TREAZ_3561	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TREAZ_3562	COG0601	transmembrane transport
TREAZ_3563	COG4166	transmembrane transport
TREAZ_3570	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TREAZ_3571	COG1690	Belongs to the RtcB family
TREAZ_3577	COG2205	protein histidine kinase activity
TREAZ_3577	COG0784	Response regulator, receiver
TREAZ_3578	COG0784	Response regulator, receiver
TREAZ_3578	COG2205	protein histidine kinase activity
TREAZ_3578	COG2198	Histidine kinase
TREAZ_3580	COG1597	lipid kinase activity
TREAZ_3582	COG0840	transmembrane signaling receptor activity
TREAZ_3584	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
TREAZ_3585	COG0737	Belongs to the 5'-nucleotidase family
TREAZ_3586	COG0297	glycogen (starch) synthase activity
TREAZ_3588	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
TREAZ_3594	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
TREAZ_3601	COG0386	Belongs to the glutathione peroxidase family
TREAZ_3602	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TREAZ_3605	COG1253	flavin adenine dinucleotide binding
TREAZ_3608	COG0436	Aminotransferase
TREAZ_3609	COG2604	Protein of unknown function DUF115
TREAZ_3610	COG1653	transport
TREAZ_3612	COG0395	ABC-type sugar transport system, permease component
TREAZ_3614	COG0768	penicillin binding
TREAZ_3616	COG0739	heme binding
TREAZ_3620	COG1686	Belongs to the peptidase S11 family
TREAZ_3621	COG0017	Asparaginyl-tRNA synthetase
TREAZ_3623	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
TREAZ_3624	COG0084	hydrolase, TatD family'
TREAZ_3626	COG0352	thiamine-phosphate diphosphorylase activity
TREAZ_3626	COG0351	phosphomethylpyrimidine kinase
TREAZ_3635	COG0204	Acyl-transferase
TREAZ_3636	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
TREAZ_3639	COG1484	DNA-dependent DNA replication
TREAZ_3642	COG0698	ribose 5-phosphate isomerase
TREAZ_3644	COG2376	Dihydroxyacetone kinase
TREAZ_3645	COG1028	Short-chain dehydrogenase reductase Sdr
TREAZ_3646	COG1063	alcohol dehydrogenase
TREAZ_3648	COG3976	FMN-binding domain protein
TREAZ_3648	COG1053	succinate dehydrogenase
TREAZ_3649	COG0445	tRNA wobble uridine modification
TREAZ_3651	COG1175	transmembrane transport
TREAZ_3652	COG0395	ABC-type sugar transport system, permease component
TREAZ_3653	COG3960	tartronate-semialdehyde synthase activity
TREAZ_3654	COG1454	alcohol dehydrogenase
TREAZ_3654	COG1012	belongs to the aldehyde dehydrogenase family
TREAZ_3656	COG0840	transmembrane signaling receptor activity
TREAZ_3658	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
TREAZ_3660	COG1702	phosphate starvation-inducible protein PhoH
TREAZ_3661	COG1480	7TM receptor with intracellular HD hydrolase
TREAZ_3662	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA