locus-tag class description Spica_0001 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0001 IPR003593 AAA+ ATPase domain Spica_0001 IPR001957 Chromosomal replication control, initiator DnaA Spica_0001 IPR038454 DnaA, N-terminal domain superfamily Spica_0001 IPR013317 Chromosomal replication initiator protein DnaA Spica_0001 IPR018312 Chromosomal replication control, initiator DnaA, conserved site Spica_0001 IPR020591 Chromosomal replication control, initiator DnaA-like Spica_0001 IPR013159 Chromosomal replication initiator, DnaA C-terminal Spica_0001 IPR024633 DnaA N-terminal domain Spica_0001 IPR010921 Trp repressor/replication initiator Spica_0002 IPR001001 DNA polymerase III, beta sliding clamp Spica_0002 IPR022637 DNA polymerase III, beta sliding clamp, central Spica_0002 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal Spica_0002 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal Spica_0003 IPR001238 DNA-binding, RecF Spica_0003 IPR018078 DNA-binding, RecF, conserved site Spica_0003 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0003 IPR003395 RecF/RecN/SMC, N-terminal Spica_0003 IPR042174 DNA-binding RecF, domain 2 Spica_0005 IPR000271 Ribosomal protein L34 Spica_0005 IPR020939 Ribosomal protein L34, conserved site Spica_0006 IPR000100 Ribonuclease P Spica_0006 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_0006 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0007 IPR019998 Membrane insertase YidC Spica_0007 IPR038221 YidC, periplasmic domain superfamily Spica_0007 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 Spica_0007 IPR038210 Membrane insertase YidC, periplasmic domain Spica_0007 IPR028053 Membrane insertase YidC, N-terminal Spica_0007 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Spica_0008 IPR034079 Jag, R3H domain Spica_0008 IPR036867 R3H domain superfamily Spica_0008 IPR038247 Jag, N-terminal domain superfamily Spica_0008 IPR001374 R3H domain Spica_0008 IPR015946 K homology domain-like, alpha/beta Spica_0008 IPR032782 Jag, N-terminal Spica_0008 IPR038008 Jag, KH domain Spica_0008 IPR039247 Jag protein Spica_0010 IPR042187 Flagellin, C-terminal domain, subdomain 2 Spica_0010 IPR001029 Flagellin, D0/D1 domain Spica_0010 IPR001492 Flagellin Spica_0012 IPR014777 Tetrapyrrole methylase, subdomain 1 Spica_0012 IPR014776 Tetrapyrrole methylase, subdomain 2 Spica_0012 IPR008189 rRNA small subunit methyltransferase I Spica_0012 IPR000878 Tetrapyrrole methylase Spica_0012 IPR018063 SAM-dependent methyltransferase RsmI, conserved site Spica_0012 IPR035996 Tetrapyrrole methylase superfamily Spica_0016 IPR013976 Metal-dependent hydrolase HDOD Spica_0017 IPR008269 Peptidase S16, Lon proteolytic domain Spica_0017 IPR027065 Lon protease Spica_0017 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_0017 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0017 IPR008268 Peptidase S16, active site Spica_0017 IPR041699 Lon protease, AAA domain Spica_0019 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_0019 IPR033479 Double Cache domain 1 Spica_0019 IPR029151 Periplasmic sensor-like domain superfamily Spica_0019 IPR003660 HAMP domain Spica_0021 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily Spica_0021 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 Spica_0022 IPR001872 Peptidase A8, signal peptidase II Spica_0027 IPR033524 Leu/Phe/Val dehydrogenases active site Spica_0027 IPR033922 NAD(P) binding domain of glutamate dehydrogenase Spica_0027 IPR036291 NAD(P)-binding domain superfamily Spica_0027 IPR014362 Glutamate dehydrogenase Spica_0027 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase Spica_0027 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain Spica_0027 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal Spica_0028 IPR016099 Prismane-like, alpha/beta-sandwich Spica_0028 IPR011254 Prismane-like superfamily Spica_0028 IPR016100 Prismane, alpha-bundle Spica_0028 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase Spica_0028 IPR010048 Hydroxylamine reductase Spica_0030 IPR015375 NADH pyrophosphatase-like, N-terminal Spica_0030 IPR022925 NADH pyrophosphatase NudC Spica_0030 IPR015797 NUDIX hydrolase-like domain superfamily Spica_0030 IPR000086 NUDIX hydrolase domain Spica_0030 IPR015376 Zinc ribbon, NADH pyrophosphatase Spica_0032 IPR003660 HAMP domain Spica_0032 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0032 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0032 IPR005467 Histidine kinase domain Spica_0032 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_0032 IPR010559 Signal transduction histidine kinase, internal region Spica_0032 IPR033479 Double Cache domain 1 Spica_0033 IPR001789 Signal transduction response regulator, receiver domain Spica_0033 IPR007492 LytTR DNA-binding domain Spica_0033 IPR011006 CheY-like superfamily Spica_0034 IPR013456 D-xylose ABC transporter, substrate-binding protein Spica_0034 IPR025997 Periplasmic binding protein Spica_0034 IPR028082 Periplasmic binding protein-like I Spica_0035 IPR028082 Periplasmic binding protein-like I Spica_0035 IPR025997 Periplasmic binding protein Spica_0036 IPR003439 ABC transporter-like Spica_0036 IPR017871 ABC transporter, conserved site Spica_0036 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0036 IPR003593 AAA+ ATPase domain Spica_0037 IPR001851 ABC transporter, permease Spica_0038 IPR002528 Multi antimicrobial extrusion protein Spica_0040 IPR007340 Opacity-associated protein A Spica_0040 IPR016047 Peptidase M23 Spica_0040 IPR011055 Duplicated hybrid motif Spica_0042 IPR024042 TM1646-like domain superfamily Spica_0042 IPR005585 Protein of unknown function DUF327 Spica_0043 IPR007557 PSP1, C-terminal Spica_0045 IPR017853 Glycoside hydrolase superfamily Spica_0045 IPR003476 Glycoside hydrolase, family 42 Spica_0045 IPR013529 Glycoside hydrolase, family 42, N-terminal Spica_0045 IPR029062 Class I glutamine amidotransferase-like Spica_0045 IPR013739 Beta-galactosidase C-terminal Spica_0045 IPR013738 Beta-galactosidase trimerisation Spica_0045 IPR013780 Glycosyl hydrolase, all-beta Spica_0046 IPR003669 Thymidylate synthase ThyX Spica_0046 IPR036098 Thymidylate synthase ThyX superfamily Spica_0047 IPR006674 HD domain Spica_0047 IPR011006 CheY-like superfamily Spica_0047 IPR003607 HD/PDEase domain Spica_0047 IPR037522 HD-GYP domain Spica_0047 IPR001789 Signal transduction response regulator, receiver domain Spica_0048 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_0048 IPR003660 HAMP domain Spica_0049 IPR000577 Carbohydrate kinase, FGGY Spica_0049 IPR018483 Carbohydrate kinase, FGGY, conserved site Spica_0049 IPR018485 Carbohydrate kinase, FGGY, C-terminal Spica_0049 IPR006000 Xylulokinase Spica_0049 IPR018484 Carbohydrate kinase, FGGY, N-terminal Spica_0050 IPR037459 Rhamnogalacturonan acetylesterase RhgT-like Spica_0050 IPR013830 SGNH hydrolase-type esterase domain Spica_0050 IPR036514 SGNH hydrolase superfamily Spica_0054 IPR011050 Pectin lyase fold/virulence factor Spica_0054 IPR002022 Pectate lyase Spica_0054 IPR012334 Pectin lyase fold Spica_0055 IPR010982 Lambda repressor-like, DNA-binding domain superfamily Spica_0055 IPR000843 LacI-type HTH domain Spica_0055 IPR023588 Transcription regulator HTH, PurR Spica_0055 IPR028082 Periplasmic binding protein-like I Spica_0058 IPR003561 Mutator MutT Spica_0058 IPR015797 NUDIX hydrolase-like domain superfamily Spica_0058 IPR020476 NUDIX hydrolase Spica_0058 IPR000086 NUDIX hydrolase domain Spica_0058 IPR020084 NUDIX hydrolase, conserved site Spica_0060 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0060 IPR035906 MetI-like superfamily Spica_0061 IPR035906 MetI-like superfamily Spica_0061 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0062 IPR003607 HD/PDEase domain Spica_0062 IPR037522 HD-GYP domain Spica_0062 IPR001789 Signal transduction response regulator, receiver domain Spica_0062 IPR011006 CheY-like superfamily Spica_0063 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type Spica_0063 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0063 IPR011604 Exonuclease, phage-type/RecB, C-terminal Spica_0063 IPR000212 DNA helicase, UvrD/REP type Spica_0063 IPR014017 UvrD-like DNA helicase, C-terminal Spica_0063 IPR034739 UvrD/AddA helicase, N-terminal Spica_0063 IPR011335 Restriction endonuclease type II-like Spica_0063 IPR014016 UvrD-like helicase, ATP-binding domain Spica_0063 IPR014152 DNA helicase subunit AddA Spica_0066 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0066 IPR020904 Short-chain dehydrogenase/reductase, conserved site Spica_0066 IPR036291 NAD(P)-binding domain superfamily Spica_0067 IPR001034 DeoR-type HTH domain Spica_0067 IPR037171 NagB/RpiA transferase-like Spica_0067 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0067 IPR036390 Winged helix DNA-binding domain superfamily Spica_0067 IPR014036 DeoR C-terminal sensor domain Spica_0067 IPR018356 Transcription regulator, HTH DeoR-type, conserved site Spica_0069 IPR011840 Pullulanase, type I Spica_0069 IPR013784 Carbohydrate-binding-like fold Spica_0069 IPR017853 Glycoside hydrolase superfamily Spica_0069 IPR013783 Immunoglobulin-like fold Spica_0069 IPR013780 Glycosyl hydrolase, all-beta Spica_0069 IPR004193 Glycoside hydrolase, family 13, N-terminal Spica_0069 IPR006047 Glycosyl hydrolase, family 13, catalytic domain Spica_0069 IPR005323 Pullulanase, carbohydrate-binding module 41 Spica_0069 IPR014756 Immunoglobulin E-set Spica_0072 IPR033403 Domain of unknown function DUF5110 Spica_0072 IPR011013 Galactose mutarotase-like domain superfamily Spica_0072 IPR000322 Glycoside hydrolase family 31 Spica_0072 IPR030459 Glycosyl hydrolases family 31, conserved site Spica_0072 IPR025887 Glycoside hydrolase family 31, N-terminal domain Spica_0072 IPR013780 Glycosyl hydrolase, all-beta Spica_0072 IPR017853 Glycoside hydrolase superfamily Spica_0072 IPR032513 Alpha-glucosidase, domain of unknown function DUF4968 Spica_0072 IPR030458 Glycosyl hydrolases family 31, active site Spica_0073 IPR039697 Iron-type alcohol dehydrogenase-like Spica_0073 IPR018211 Alcohol dehydrogenase, iron-type, conserved site Spica_0073 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA Spica_0074 IPR003660 HAMP domain Spica_0074 IPR025919 Stimulus-sensing domain Spica_0074 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_0074 IPR025908 Sensor N-terminal transmembrane domain Spica_0074 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_0074 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_0074 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0074 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0074 IPR005467 Histidine kinase domain Spica_0083 IPR001789 Signal transduction response regulator, receiver domain Spica_0083 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0083 IPR039420 Transcriptional regulatory protein WalR-like Spica_0083 IPR011006 CheY-like superfamily Spica_0083 IPR001867 OmpR/PhoB-type DNA-binding domain Spica_0083 IPR016032 Signal transduction response regulator, C-terminal effector Spica_0085 IPR011840 Pullulanase, type I Spica_0085 IPR004193 Glycoside hydrolase, family 13, N-terminal Spica_0085 IPR014756 Immunoglobulin E-set Spica_0085 IPR013783 Immunoglobulin-like fold Spica_0085 IPR017853 Glycoside hydrolase superfamily Spica_0085 IPR013780 Glycosyl hydrolase, all-beta Spica_0085 IPR040697 Pullulanase, N1 domain Spica_0085 IPR006047 Glycosyl hydrolase, family 13, catalytic domain Spica_0086 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) Spica_0086 IPR006047 Glycosyl hydrolase, family 13, catalytic domain Spica_0086 IPR017853 Glycoside hydrolase superfamily Spica_0088 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0088 IPR035906 MetI-like superfamily Spica_0089 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0089 IPR035906 MetI-like superfamily Spica_0091 IPR013783 Immunoglobulin-like fold Spica_0091 IPR017853 Glycoside hydrolase superfamily Spica_0091 IPR013780 Glycosyl hydrolase, all-beta Spica_0091 IPR032091 Maltogenic Amylase, C-terminal Spica_0091 IPR006047 Glycosyl hydrolase, family 13, catalytic domain Spica_0091 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain Spica_0094 IPR015797 NUDIX hydrolase-like domain superfamily Spica_0102 IPR041405 Type III R-M EcoP15I, C-terminal Spica_0102 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0102 IPR002052 DNA methylase, N-6 adenine-specific, conserved site Spica_0102 IPR002941 DNA methylase N-4/N-6 Spica_0102 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class Spica_0108 IPR022907 VapC family Spica_0108 IPR002716 PIN domain Spica_0108 IPR029060 PIN-like domain superfamily Spica_0109 IPR037914 SpoVT-AbrB domain superfamily Spica_0109 IPR007159 SpoVT-AbrB domain Spica_0116 IPR000160 GGDEF domain Spica_0116 IPR029787 Nucleotide cyclase Spica_0116 IPR001789 Signal transduction response regulator, receiver domain Spica_0116 IPR011006 CheY-like superfamily Spica_0118 IPR015424 Pyridoxal phosphate-dependent transferase Spica_0118 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_0118 IPR001085 Serine hydroxymethyltransferase Spica_0118 IPR039429 Serine hydroxymethyltransferase-like domain Spica_0118 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site Spica_0119 IPR005624 Haem-degrading Spica_0119 IPR010371 Uncharacterised protein family UPF0303 Spica_0119 IPR038084 GlcG-like domain superfamily Spica_0122 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0122 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0122 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain Spica_0123 IPR011006 CheY-like superfamily Spica_0123 IPR000792 Transcription regulator LuxR, C-terminal Spica_0123 IPR016032 Signal transduction response regulator, C-terminal effector Spica_0123 IPR001789 Signal transduction response regulator, receiver domain Spica_0125 IPR025997 Periplasmic binding protein Spica_0125 IPR028082 Periplasmic binding protein-like I Spica_0126 IPR028082 Periplasmic binding protein-like I Spica_0126 IPR025997 Periplasmic binding protein Spica_0128 IPR001851 ABC transporter, permease Spica_0129 IPR000669 Mannitol dehydrogenase Spica_0129 IPR023027 Mannitol dehydrogenase, conserved site Spica_0129 IPR013118 Mannitol dehydrogenase, C-terminal Spica_0129 IPR013131 Mannitol dehydrogenase, N-terminal Spica_0129 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily Spica_0129 IPR013328 6-phosphogluconate dehydrogenase, domain 2 Spica_0129 IPR023028 Mannitol-1-phosphate 5-dehydrogenase Spica_0129 IPR036291 NAD(P)-binding domain superfamily Spica_0134 IPR001433 Oxidoreductase FAD/NAD(P)-binding Spica_0134 IPR017938 Riboflavin synthase-like beta-barrel Spica_0134 IPR017927 FAD-binding domain, ferredoxin reductase-type Spica_0134 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain Spica_0134 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit Spica_0134 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Spica_0134 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Spica_0135 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_0135 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_0135 IPR028261 Dihydroprymidine dehydrogenase domain II Spica_0135 IPR009051 Alpha-helical ferredoxin Spica_0135 IPR006006 Glutamate synthase, NADH/NADPH, small subunit 2 Spica_0135 IPR023753 FAD/NAD(P)-binding domain Spica_0135 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0136 IPR018490 Cyclic nucleotide-binding-like Spica_0136 IPR018488 Cyclic nucleotide-binding, conserved site Spica_0136 IPR014710 RmlC-like jelly roll fold Spica_0136 IPR027378 Cyclic nucleotide-regulated ion channel, N-terminal Spica_0136 IPR013099 Potassium channel domain Spica_0136 IPR000595 Cyclic nucleotide-binding domain Spica_0137 IPR036907 5'-Nucleotidase, C-terminal domain superfamily Spica_0137 IPR008334 5'-Nucleotidase, C-terminal Spica_0137 IPR006420 NAD pyrophosphatase/5-nucleotidase NadN Spica_0137 IPR029052 Metallo-dependent phosphatase-like Spica_0137 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type Spica_0137 IPR006146 5'-Nucleotidase, conserved site Spica_0137 IPR006179 5'-Nucleotidase/apyrase Spica_0142 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain Spica_0147 IPR035906 MetI-like superfamily Spica_0147 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0148 IPR035906 MetI-like superfamily Spica_0148 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0149 IPR006059 Bacterial extracellular solute-binding protein Spica_0150 IPR000792 Transcription regulator LuxR, C-terminal Spica_0150 IPR016032 Signal transduction response regulator, C-terminal effector Spica_0150 IPR001789 Signal transduction response regulator, receiver domain Spica_0150 IPR011006 CheY-like superfamily Spica_0151 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0151 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain Spica_0152 IPR037284 SUF system FeS cluster assembly, SufBD superfamily Spica_0152 IPR000825 SUF system FeS cluster assembly, SufBD Spica_0152 IPR010231 SUF system FeS cluster assembly, SufB Spica_0153 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0153 IPR010230 FeS cluster assembly SUF system, ATPase SufC Spica_0153 IPR017871 ABC transporter, conserved site Spica_0153 IPR003439 ABC transporter-like Spica_0156 IPR005146 B3/B4 tRNA-binding domain Spica_0156 IPR009061 Putative DNA-binding domain superfamily Spica_0156 IPR005147 tRNA synthetase, B5-domain Spica_0156 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 Spica_0156 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic Spica_0156 IPR041616 Phenylalanyl tRNA synthetase beta chain, core domain Spica_0156 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal Spica_0157 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal Spica_0157 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit Spica_0157 IPR006195 Aminoacyl-tRNA synthetase, class II Spica_0157 IPR002319 Phenylalanyl-tRNA synthetase Spica_0160 IPR035952 Rhomboid-like superfamily Spica_0160 IPR023662 Rhomboid protease GlpG Spica_0160 IPR038236 GlpG peptidase, N-terminal domain superfamily Spica_0160 IPR022732 Peptidase S54, GlpG peptidase, N-terminal Spica_0160 IPR022764 Peptidase S54, rhomboid domain Spica_0162 IPR029787 Nucleotide cyclase Spica_0162 IPR000160 GGDEF domain Spica_0162 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region Spica_0163 IPR013785 Aldolase-type TIM barrel Spica_0163 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 Spica_0163 IPR001269 tRNA-dihydrouridine synthase Spica_0163 IPR018517 tRNA-dihydrouridine synthase, conserved site Spica_0163 IPR035587 DUS-like, FMN-binding domain Spica_0164 IPR018228 Deoxyribonuclease, TatD-related, conserved site Spica_0164 IPR015991 Uncharacterised hydrolase TatD-type Spica_0164 IPR032466 Metal-dependent hydrolase Spica_0164 IPR001130 TatD family Spica_0166 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal Spica_0166 IPR011549 Riboflavin-specific deaminase, C-terminal Spica_0166 IPR004794 Riboflavin biosynthesis protein RibD Spica_0166 IPR016192 APOBEC/CMP deaminase, zinc-binding Spica_0166 IPR024072 Dihydrofolate reductase-like domain superfamily Spica_0166 IPR002125 Cytidine and deoxycytidylate deaminase domain Spica_0166 IPR016193 Cytidine deaminase-like Spica_0167 IPR026017 Lumazine-binding domain Spica_0167 IPR001783 Lumazine-binding protein Spica_0167 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily Spica_0167 IPR017938 Riboflavin synthase-like beta-barrel Spica_0168 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily Spica_0168 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB Spica_0168 IPR032677 GTP cyclohydrolase II Spica_0168 IPR000926 GTP cyclohydrolase II, RibA Spica_0168 IPR036144 RibA-like superfamily Spica_0168 IPR016299 Riboflavin biosynthesis protein RibBA Spica_0169 IPR036467 Lumazine/riboflavin synthase superfamily Spica_0169 IPR002180 Lumazine/riboflavin synthase Spica_0169 IPR034964 Lumazine synthase Spica_0170 IPR029056 Ribokinase-like Spica_0170 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Spica_0170 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase Spica_0171 IPR029056 Ribokinase-like Spica_0171 IPR000417 Hydroxyethylthiazole kinase Spica_0172 IPR036206 Thiamin phosphate synthase superfamily Spica_0172 IPR034291 Thiamine phosphate synthase Spica_0172 IPR013785 Aldolase-type TIM barrel Spica_0172 IPR022998 Thiamine phosphate synthase/TenI Spica_0173 IPR006439 HAD hydrolase, subfamily IA Spica_0173 IPR041492 Haloacid dehalogenase-like hydrolase Spica_0173 IPR023198 Phosphoglycolate phosphatase-like, domain 2 Spica_0173 IPR036412 HAD-like superfamily Spica_0173 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic Spica_0173 IPR023214 HAD superfamily Spica_0174 IPR005801 ADC synthase Spica_0174 IPR015890 Chorismate-utilising enzyme, C-terminal Spica_0174 IPR005256 Anthranilate synthase component I, PabB-like Spica_0174 IPR006805 Anthranilate synthase component I, N-terminal Spica_0174 IPR019999 Anthranilate synthase component I-like Spica_0175 IPR005940 Anthranilate phosphoribosyl transferase Spica_0175 IPR029062 Class I glutamine amidotransferase-like Spica_0175 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain Spica_0175 IPR017459 Glycosyl transferase family 3, N-terminal domain Spica_0175 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Spica_0175 IPR017926 Glutamine amidotransferase Spica_0175 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Spica_0175 IPR000312 Glycosyl transferase, family 3 Spica_0177 IPR001926 Pyridoxal-phosphate dependent enzyme Spica_0177 IPR006654 Tryptophan synthase, beta chain Spica_0177 IPR006653 Tryptophan synthase, beta chain, conserved site Spica_0177 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spica_0177 IPR023026 Tryptophan synthase beta chain/beta chain-like Spica_0178 IPR013785 Aldolase-type TIM barrel Spica_0178 IPR002028 Tryptophan synthase, alpha chain Spica_0178 IPR018204 Tryptophan synthase, alpha chain, active site Spica_0178 IPR011060 Ribulose-phosphate binding barrel Spica_0179 IPR013704 Uncharacterised protein family UPF0313, N-terminal Spica_0179 IPR024560 Uncharacterised protein family UPF0313, C-terminal Spica_0179 IPR022946 Uncharacterised protein family UPF0313 Spica_0179 IPR023404 Radical SAM, alpha/beta horseshoe Spica_0179 IPR007197 Radical SAM Spica_0179 IPR006638 Elp3/MiaB/NifB Spica_0180 IPR034904 Fe-S cluster assembly domain superfamily Spica_0180 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal Spica_0182 IPR022953 ATP-dependent 6-phosphofructokinase Spica_0182 IPR000023 Phosphofructokinase domain Spica_0182 IPR035966 Phosphofructokinase superfamily Spica_0182 IPR012004 Pyrophosphate-dependent phosphofructokinase TP0108-type Spica_0185 IPR036641 HPT domain superfamily Spica_0185 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_0185 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0185 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spica_0185 IPR011006 CheY-like superfamily Spica_0185 IPR005467 Histidine kinase domain Spica_0185 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_0185 IPR001789 Signal transduction response regulator, receiver domain Spica_0185 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain Spica_0185 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_0185 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0186 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spica_0186 IPR029064 50S ribosomal protein L30e-like Spica_0186 IPR001537 tRNA/rRNA methyltransferase, SpoU type Spica_0186 IPR004441 RNA methyltransferase TrmH family Spica_0186 IPR029028 Alpha/beta knot methyltransferases Spica_0186 IPR013123 RNA 2-O ribose methyltransferase, substrate binding Spica_0187 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily Spica_0187 IPR003156 DHHA1 domain Spica_0187 IPR012947 Threonyl/alanyl tRNA synthetase, SAD Spica_0187 IPR009000 Translation protein, beta-barrel domain superfamily Spica_0187 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily Spica_0187 IPR002318 Alanine-tRNA ligase, class IIc Spica_0187 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria Spica_0187 IPR018165 Alanyl-tRNA synthetase, class IIc, core domain Spica_0187 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal Spica_0188 IPR036451 Cobalamin adenosyltransferase-like superfamily Spica_0188 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type Spica_0188 IPR016030 Cobalamin adenosyltransferase-like Spica_0192 IPR001036 Acriflavin resistance protein Spica_0192 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_0194 IPR022337 Inositol monophosphatase, SuhB Spica_0194 IPR020550 Inositol monophosphatase, conserved site Spica_0194 IPR000760 Inositol monophosphatase-like Spica_0194 IPR020583 Inositol monophosphatase, metal-binding site Spica_0194 IPR033942 Inositol monophosphatase Spica_0195 IPR003374 ApbE-like superfamily Spica_0195 IPR042159 Flavin-trafficking protein ApbE Spica_0195 IPR024932 Flavin transferase ApbE Spica_0197 IPR029000 Cyclophilin-like domain superfamily Spica_0197 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site Spica_0197 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain Spica_0198 IPR019247 Histidine kinase BarA, N-terminal Spica_0198 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_0198 IPR003660 HAMP domain Spica_0198 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_0198 IPR011006 CheY-like superfamily Spica_0198 IPR001789 Signal transduction response regulator, receiver domain Spica_0198 IPR005467 Histidine kinase domain Spica_0198 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain Spica_0198 IPR036641 HPT domain superfamily Spica_0198 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_0198 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0198 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0199 IPR000577 Carbohydrate kinase, FGGY Spica_0199 IPR018485 Carbohydrate kinase, FGGY, C-terminal Spica_0199 IPR018483 Carbohydrate kinase, FGGY, conserved site Spica_0199 IPR005999 Glycerol kinase Spica_0199 IPR018484 Carbohydrate kinase, FGGY, N-terminal Spica_0201 IPR034137 RecR, TOPRIM domain Spica_0201 IPR006171 TOPRIM domain Spica_0201 IPR015967 Recombination protein RecR, conserved site Spica_0201 IPR023628 Recombination protein RecR, C4-type zinc finger Spica_0201 IPR023627 Recombination protein RecR Spica_0201 IPR000093 DNA recombination protein RecR Spica_0202 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily Spica_0202 IPR004401 Nucleoid-associated protein YbaB/EbfC family Spica_0203 IPR038249 DNA polymerase III, tau subunit, C-terminal domain superfamily Spica_0203 IPR003593 AAA+ ATPase domain Spica_0203 IPR001270 ClpA/B family Spica_0203 IPR021029 DNA polymerase III, tau subunit, domain V Spica_0203 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0203 IPR022001 DNA polymerase III subunit tau, DnaB-binding domain IV Spica_0203 IPR012763 DNA polymerase III, subunit gamma/ tau Spica_0203 IPR022754 DNA polymerase III, gamma subunit, domain III Spica_0203 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal Spica_0210 IPR035906 MetI-like superfamily Spica_0210 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0211 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0211 IPR035906 MetI-like superfamily Spica_0213 IPR001789 Signal transduction response regulator, receiver domain Spica_0213 IPR000792 Transcription regulator LuxR, C-terminal Spica_0213 IPR016032 Signal transduction response regulator, C-terminal effector Spica_0213 IPR011006 CheY-like superfamily Spica_0214 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0214 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain Spica_0221 IPR036010 2Fe-2S ferredoxin-like superfamily Spica_0221 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding Spica_0221 IPR013352 Iron hydrogenase, subset Spica_0221 IPR036991 Iron hydrogenase, small subunit superfamily Spica_0221 IPR003149 Iron hydrogenase, small subunit Spica_0221 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain Spica_0221 IPR009016 Iron hydrogenase Spica_0221 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_0221 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0221 IPR004108 Iron hydrogenase, large subunit, C-terminal Spica_0222 IPR004027 SEC-C motif Spica_0222 IPR023006 Uncharacterised protein family UPF0225 Spica_0222 IPR032710 NTF2-like domain superfamily Spica_0223 IPR000620 EamA domain Spica_0225 IPR036968 Enolpyruvate transferase domain superfamily Spica_0225 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta Spica_0225 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase Spica_0225 IPR001986 Enolpyruvate transferase domain Spica_0226 IPR008971 HSP40/DnaJ peptide-binding Spica_0226 IPR001305 Heat shock protein DnaJ, cysteine-rich domain Spica_0226 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily Spica_0226 IPR036869 Chaperone J-domain superfamily Spica_0226 IPR002939 Chaperone DnaJ, C-terminal Spica_0226 IPR012724 Chaperone DnaJ Spica_0226 IPR001623 DnaJ domain Spica_0226 IPR018253 DnaJ domain, conserved site Spica_0229 IPR001789 Signal transduction response regulator, receiver domain Spica_0229 IPR039420 Transcriptional regulatory protein WalR-like Spica_0229 IPR001867 OmpR/PhoB-type DNA-binding domain Spica_0229 IPR011006 CheY-like superfamily Spica_0229 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0229 IPR016032 Signal transduction response regulator, C-terminal effector Spica_0230 IPR007157 PspA/IM30 Spica_0233 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0233 IPR020904 Short-chain dehydrogenase/reductase, conserved site Spica_0233 IPR036291 NAD(P)-binding domain superfamily Spica_0233 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase Spica_0234 IPR029028 Alpha/beta knot methyltransferases Spica_0234 IPR004384 RNA methyltransferase TrmJ/LasT Spica_0234 IPR001537 tRNA/rRNA methyltransferase, SpoU type Spica_0234 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spica_0236 IPR002197 DNA binding HTH domain, Fis-type Spica_0236 IPR003593 AAA+ ATPase domain Spica_0236 IPR011006 CheY-like superfamily Spica_0236 IPR009057 Homeobox-like domain superfamily Spica_0236 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0236 IPR001789 Signal transduction response regulator, receiver domain Spica_0236 IPR002078 RNA polymerase sigma factor 54 interaction domain Spica_0236 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_0236 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_0236 IPR025944 Sigma-54 interaction domain, conserved site Spica_0238 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spica_0238 IPR029028 Alpha/beta knot methyltransferases Spica_0238 IPR001206 Diacylglycerol kinase, catalytic domain Spica_0238 IPR006700 Ribosomal RNA small subunit methyltransferase E Spica_0238 IPR015947 PUA-like superfamily Spica_0239 IPR005151 Tail specific protease Spica_0239 IPR036365 PGBD-like superfamily Spica_0239 IPR004447 C-terminal-processing peptidase S41A Spica_0239 IPR036366 PGBD superfamily Spica_0239 IPR036034 PDZ superfamily Spica_0239 IPR002477 Peptidoglycan binding-like Spica_0239 IPR001478 PDZ domain Spica_0239 IPR029045 ClpP/crotonase-like domain superfamily Spica_0241 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0241 IPR025501 ATP binding protein MinD Spica_0241 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 Spica_0243 IPR001640 Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase Lgt Spica_0244 IPR004450 Threonine synthase-like Spica_0244 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spica_0244 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site Spica_0244 IPR029144 Threonine synthase, N-terminal Spica_0244 IPR001926 Pyridoxal-phosphate dependent enzyme Spica_0244 IPR037158 Threonine synthase, N-terminal domain superfamily Spica_0245 IPR002068 Alpha crystallin/Hsp20 domain Spica_0245 IPR008978 HSP20-like chaperone Spica_0248 IPR005478 Transketolase, bacterial-like Spica_0248 IPR033247 Transketolase family Spica_0248 IPR005475 Transketolase-like, pyrimidine-binding domain Spica_0248 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II Spica_0248 IPR005474 Transketolase, N-terminal Spica_0248 IPR020826 Transketolase binding site Spica_0248 IPR029061 Thiamin diphosphate-binding fold Spica_0250 IPR018193 Glycerate kinase, flavodoxin-like fold Spica_0250 IPR004381 Glycerate kinase Spica_0250 IPR036129 Glycerate kinase superfamily Spica_0250 IPR018197 Glycerate kinase, restriction-enzyme-like fold Spica_0251 IPR008599 Putative sugar diacid recognition Spica_0251 IPR041522 CdaR, GGDEF-like domain Spica_0251 IPR025736 PucR C-terminal helix-turn-helix domain Spica_0251 IPR042070 PucR C-terminal helix-turn-helix domain superfamily Spica_0252 IPR006690 Outer membrane protein, OmpA-like, conserved site Spica_0252 IPR006665 OmpA-like domain Spica_0252 IPR036737 OmpA-like domain superfamily Spica_0252 IPR006664 Outer membrane protein, bacterial Spica_0252 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel Spica_0252 IPR008722 Outer membrane porin F, N-terminal Spica_0252 IPR028974 TSP type-3 repeat Spica_0253 IPR001045 Spermidine/spermine synthases Spica_0253 IPR030374 Polyamine biosynthesis domain Spica_0253 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0253 IPR035246 Spermidine synthase, tetramerisation domain Spica_0253 IPR037163 Spermidine synthase, tetramerisation domain superfamily Spica_0254 IPR009165 S-adenosylmethionine decarboxylase, bacterial Spica_0254 IPR016067 S-adenosylmethionine decarboxylase, core Spica_0254 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic Spica_0257 IPR036259 MFS transporter superfamily Spica_0257 IPR020846 Major facilitator superfamily domain Spica_0257 IPR011701 Major facilitator superfamily Spica_0269 IPR004524 Aspartate-tRNA ligase, type 1 Spica_0269 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type Spica_0269 IPR029351 GAD domain Spica_0269 IPR004115 GAD-like domain superfamily Spica_0269 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) Spica_0269 IPR006195 Aminoacyl-tRNA synthetase, class II Spica_0269 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb Spica_0269 IPR012340 Nucleic acid-binding, OB-fold Spica_0270 IPR003416 MgtC/SapB/SrpB/YhiD family Spica_0271 IPR005358 Putative zinc- or iron-chelating domain containing protein Spica_0274 IPR000577 Carbohydrate kinase, FGGY Spica_0274 IPR018484 Carbohydrate kinase, FGGY, N-terminal Spica_0274 IPR018485 Carbohydrate kinase, FGGY, C-terminal Spica_0275 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site Spica_0275 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type Spica_0275 IPR005946 Ribose-phosphate pyrophosphokinase Spica_0275 IPR029057 Phosphoribosyltransferase-like Spica_0275 IPR000836 Phosphoribosyltransferase domain Spica_0275 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain Spica_0276 IPR006664 Outer membrane protein, bacterial Spica_0276 IPR006665 OmpA-like domain Spica_0276 IPR006690 Outer membrane protein, OmpA-like, conserved site Spica_0276 IPR036737 OmpA-like domain superfamily Spica_0279 IPR037914 SpoVT-AbrB domain superfamily Spica_0279 IPR007159 SpoVT-AbrB domain Spica_0280 IPR002716 PIN domain Spica_0280 IPR029060 PIN-like domain superfamily Spica_0280 IPR022907 VapC family Spica_0285 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0285 IPR041682 AAA domain, group 14 Spica_0285 IPR025420 Domain of unknown function DUF4143 Spica_0286 IPR016905 Glycyl radical enzyme, HI0521, predicted Spica_0287 IPR007197 Radical SAM Spica_0287 IPR001989 Radical-activating enzyme, conserved site Spica_0287 IPR013785 Aldolase-type TIM barrel Spica_0287 IPR034457 Organic radical-activating enzymes Spica_0291 IPR010383 Glycosyl hydrolase 94 Spica_0291 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily Spica_0291 IPR037828 N,N'-diacetylchitobiose phosphorylase, N-terminal Spica_0291 IPR033432 Glycosyl hydrolase 36, catalytic domain Spica_0291 IPR008928 Six-hairpin glycosidase superfamily Spica_0291 IPR012341 Six-hairpin glycosidase-like superfamily Spica_0291 IPR009342 Putative carbohydrate binding domain Spica_0291 IPR011013 Galactose mutarotase-like domain superfamily Spica_0294 IPR000873 AMP-dependent synthetase/ligase Spica_0294 IPR042099 AMP-dependent synthetase-like superfamily Spica_0294 IPR020845 AMP-binding, conserved site Spica_0295 IPR011006 CheY-like superfamily Spica_0295 IPR037522 HD-GYP domain Spica_0295 IPR001789 Signal transduction response regulator, receiver domain Spica_0295 IPR003607 HD/PDEase domain Spica_0296 IPR005467 Histidine kinase domain Spica_0296 IPR011006 CheY-like superfamily Spica_0296 IPR003660 HAMP domain Spica_0296 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_0296 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0296 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0296 IPR036641 HPT domain superfamily Spica_0296 IPR033414 Periplasmic sensor domain Spica_0296 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_0296 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_0296 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain Spica_0296 IPR001789 Signal transduction response regulator, receiver domain Spica_0298 IPR001404 Heat shock protein Hsp90 family Spica_0298 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0298 IPR019805 Heat shock protein Hsp90, conserved site Spica_0298 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0298 IPR037196 HSP90, C-terminal domain Spica_0298 IPR020575 Heat shock protein Hsp90, N-terminal Spica_0299 IPR013785 Aldolase-type TIM barrel Spica_0299 IPR031705 Glycosyl hydrolase family 36, C-terminal Spica_0299 IPR000111 Glycoside hydrolase family 27/36, conserved site Spica_0299 IPR002252 Glycoside hydrolase family 36 Spica_0299 IPR017853 Glycoside hydrolase superfamily Spica_0299 IPR013780 Glycosyl hydrolase, all-beta Spica_0299 IPR031704 Glycosyl hydrolase family 36, N-terminal Spica_0299 IPR038417 Alpha-galactosidase, N-terminal domain superfamily Spica_0301 IPR003593 AAA+ ATPase domain Spica_0301 IPR011527 ABC transporter type 1, transmembrane domain Spica_0301 IPR036640 ABC transporter type 1, transmembrane domain superfamily Spica_0301 IPR003439 ABC transporter-like Spica_0301 IPR017871 ABC transporter, conserved site Spica_0301 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0301 IPR039421 Type I protein exporter Spica_0302 IPR039421 Type I protein exporter Spica_0302 IPR003439 ABC transporter-like Spica_0302 IPR036640 ABC transporter type 1, transmembrane domain superfamily Spica_0302 IPR011527 ABC transporter type 1, transmembrane domain Spica_0302 IPR003593 AAA+ ATPase domain Spica_0302 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0304 IPR019833 Manganese/iron superoxide dismutase, binding site Spica_0304 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily Spica_0304 IPR019832 Manganese/iron superoxide dismutase, C-terminal Spica_0304 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily Spica_0304 IPR001189 Manganese/iron superoxide dismutase Spica_0304 IPR019831 Manganese/iron superoxide dismutase, N-terminal Spica_0305 IPR022877 Protein of unknown funcion UPF0173 Spica_0305 IPR001279 Metallo-beta-lactamase Spica_0305 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_0306 IPR020904 Short-chain dehydrogenase/reductase, conserved site Spica_0306 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0306 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase Spica_0306 IPR036291 NAD(P)-binding domain superfamily Spica_0307 IPR028082 Periplasmic binding protein-like I Spica_0307 IPR010982 Lambda repressor-like, DNA-binding domain superfamily Spica_0307 IPR000843 LacI-type HTH domain Spica_0307 IPR023588 Transcription regulator HTH, PurR Spica_0308 IPR001789 Signal transduction response regulator, receiver domain Spica_0308 IPR000792 Transcription regulator LuxR, C-terminal Spica_0308 IPR016032 Signal transduction response regulator, C-terminal effector Spica_0308 IPR011006 CheY-like superfamily Spica_0309 IPR008928 Six-hairpin glycosidase superfamily Spica_0309 IPR012341 Six-hairpin glycosidase-like superfamily Spica_0309 IPR000852 Glycoside hydrolase, family 52 Spica_0310 IPR006059 Bacterial extracellular solute-binding protein Spica_0311 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0311 IPR035906 MetI-like superfamily Spica_0312 IPR035906 MetI-like superfamily Spica_0312 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0313 IPR011852 TRAP transporter solute receptor, TAXI family Spica_0319 IPR029787 Nucleotide cyclase Spica_0319 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase Spica_0321 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site Spica_0321 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_0321 IPR016454 Cysteine desulfurase Spica_0321 IPR010970 Cysteine desulfurase, SufS Spica_0321 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_0321 IPR000192 Aminotransferase class V domain Spica_0321 IPR015424 Pyridoxal phosphate-dependent transferase Spica_0322 IPR011542 SUF system FeS cluster assembly, SufD Spica_0322 IPR000825 SUF system FeS cluster assembly, SufBD Spica_0322 IPR037284 SUF system FeS cluster assembly, SufBD superfamily Spica_0323 IPR010231 SUF system FeS cluster assembly, SufB Spica_0323 IPR037284 SUF system FeS cluster assembly, SufBD superfamily Spica_0323 IPR000825 SUF system FeS cluster assembly, SufBD Spica_0324 IPR003439 ABC transporter-like Spica_0324 IPR017871 ABC transporter, conserved site Spica_0324 IPR003593 AAA+ ATPase domain Spica_0324 IPR010230 FeS cluster assembly SUF system, ATPase SufC Spica_0324 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0326 IPR003680 Flavodoxin-like fold Spica_0326 IPR029039 Flavoprotein-like superfamily Spica_0327 IPR006700 Ribosomal RNA small subunit methyltransferase E Spica_0327 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spica_0327 IPR029028 Alpha/beta knot methyltransferases Spica_0331 IPR000811 Glycosyl transferase, family 35 Spica_0331 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 Spica_0331 IPR035090 Phosphorylase pyridoxal-phosphate attachment site Spica_0331 IPR011834 Alpha-glucan phosphorylase Spica_0333 IPR014284 RNA polymerase sigma-70 like domain Spica_0333 IPR007627 RNA polymerase sigma-70 region 2 Spica_0333 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 Spica_0333 IPR014286 RNA polymerase sigma-70 RpoE type Spica_0333 IPR013325 RNA polymerase sigma factor, region 2 Spica_0333 IPR039425 RNA polymerase sigma-70 like Spica_0333 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_0333 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0333 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site Spica_0337 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_0337 IPR017752 Glycerol-3-phosphate dehydrogenase, GlpA subunit Spica_0337 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase Spica_0337 IPR007419 BFD-like [2Fe-2S]-binding domain Spica_0337 IPR006076 FAD dependent oxidoreductase Spica_0337 IPR041854 BFD-like [2Fe-2S]-binding domain superfamily Spica_0340 IPR025121 GTPase HflX, N-terminal Spica_0340 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0340 IPR006073 GTP binding domain Spica_0340 IPR032305 GTP-binding protein, middle domain Spica_0340 IPR030394 HflX-type guanine nucleotide-binding (G) domain Spica_0340 IPR042108 GTPase HflX, N-terminal domain superfamily Spica_0340 IPR016496 GTPase HflX Spica_0341 IPR010090 Phage tail tape measure protein Spica_0341 IPR023346 Lysozyme-like domain superfamily Spica_0341 IPR008258 Transglycosylase SLT domain 1 Spica_0341 IPR016047 Peptidase M23 Spica_0341 IPR011055 Duplicated hybrid motif Spica_0341 IPR000189 Prokaryotic transglycosylase, active site Spica_0346 IPR036104 Bifunctional nuclease superfamily Spica_0346 IPR003729 Bifunctional nuclease domain Spica_0347 IPR008949 Isoprenoid synthase domain superfamily Spica_0347 IPR000092 Polyprenyl synthetase Spica_0347 IPR033749 Polyprenyl synthetase, conserved site Spica_0348 IPR015507 Ribosomal RNA large subunit methyltransferase E Spica_0348 IPR002877 Ribosomal RNA methyltransferase FtsJ domain Spica_0348 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0352 IPR000600 ROK family Spica_0352 IPR036390 Winged helix DNA-binding domain superfamily Spica_0352 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0353 IPR006059 Bacterial extracellular solute-binding protein Spica_0354 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0354 IPR035906 MetI-like superfamily Spica_0356 IPR009342 Putative carbohydrate binding domain Spica_0356 IPR008928 Six-hairpin glycosidase superfamily Spica_0356 IPR011013 Galactose mutarotase-like domain superfamily Spica_0356 IPR033432 Glycosyl hydrolase 36, catalytic domain Spica_0356 IPR037825 Cellobiose phosphorylase, N-terminal Spica_0356 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily Spica_0356 IPR012341 Six-hairpin glycosidase-like superfamily Spica_0356 IPR010383 Glycosyl hydrolase 94 Spica_0359 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Spica_0359 IPR006073 GTP binding domain Spica_0359 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0359 IPR011640 Ferrous iron transport protein B, C-terminal Spica_0359 IPR041069 FeoB, cytosolic helical domain Spica_0359 IPR038157 Ferrous iron transporter, core domain Spica_0359 IPR003373 Ferrous iron transport protein B Spica_0359 IPR030389 FeoB-type guanine nucleotide-binding (G) domain Spica_0359 IPR005225 Small GTP-binding protein domain Spica_0359 IPR008988 Transcriptional repressor, C-terminal Spica_0359 IPR007167 Ferrous iron transporter FeoA domain Spica_0360 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0360 IPR036291 NAD(P)-binding domain superfamily Spica_0361 IPR002543 FtsK domain Spica_0361 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0361 IPR018541 FtsK gamma domain Spica_0361 IPR041027 FtsK alpha domain Spica_0361 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0361 IPR003593 AAA+ ATPase domain Spica_0361 IPR036390 Winged helix DNA-binding domain superfamily Spica_0365 IPR003798 DNA recombination RmuC Spica_0366 IPR002825 Peptidase S49, serine-peptidase prokaryotes Spica_0366 IPR002810 NfeD-like, C-terminal domain Spica_0366 IPR029045 ClpP/crotonase-like domain superfamily Spica_0367 IPR022853 Uncharacterised protein family YdfA-immunity Spica_0370 IPR004402 Purine nucleoside phosphorylase DeoD-type Spica_0370 IPR018016 Nucleoside phosphorylase, conserved site Spica_0370 IPR000845 Nucleoside phosphorylase domain Spica_0370 IPR035994 Nucleoside phosphorylase superfamily Spica_0371 IPR039672 Lactose permease-like Spica_0371 IPR018043 Sodium:galactoside symporter, conserved site Spica_0371 IPR036259 MFS transporter superfamily Spica_0372 IPR001705 Ribosomal protein L33 Spica_0372 IPR018264 Ribosomal protein L33, conserved site Spica_0372 IPR011332 Zinc-binding ribosomal protein Spica_0372 IPR038584 Ribosomal protein L33 superfamily Spica_0373 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit Spica_0373 IPR038379 SecE superfamily Spica_0373 IPR005807 SecE subunit of protein translocation complex, bacterial-like Spica_0374 IPR005824 KOW Spica_0374 IPR036735 NusG, N-terminal domain superfamily Spica_0374 IPR008991 Translation protein SH3-like domain superfamily Spica_0374 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site Spica_0374 IPR001062 Transcription antitermination protein, NusG Spica_0374 IPR014722 Ribosomal protein L2, domain 2 Spica_0374 IPR006645 NusG, N-terminal Spica_0375 IPR020785 Ribosomal protein L11, conserved site Spica_0375 IPR006519 Ribosomal protein L11, bacterial-type Spica_0375 IPR020783 Ribosomal protein L11, C-terminal Spica_0375 IPR036769 Ribosomal protein L11, C-terminal domain superfamily Spica_0375 IPR020784 Ribosomal protein L11, N-terminal Spica_0375 IPR000911 Ribosomal protein L11/L12 Spica_0375 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily Spica_0376 IPR023673 Ribosomal protein L1, conserved site Spica_0376 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich Spica_0376 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein Spica_0376 IPR023674 Ribosomal protein L1-like Spica_0376 IPR005878 Ribosomal protein L1, bacterial-type Spica_0376 IPR002143 Ribosomal protein L1 Spica_0377 IPR022973 Ribosomal protein L10 Spica_0377 IPR001790 Ribosomal protein L10P Spica_0378 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily Spica_0378 IPR013823 Ribosomal protein L7/L12, C-terminal Spica_0378 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Spica_0378 IPR000206 Ribosomal protein L7/L12 Spica_0378 IPR008932 Ribosomal protein L7/L12, oligomerisation Spica_0379 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain Spica_0379 IPR037034 RNA polymerase Rpb2, domain 2 superfamily Spica_0379 IPR007645 RNA polymerase Rpb2, domain 3 Spica_0379 IPR007641 RNA polymerase Rpb2, domain 7 Spica_0379 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily Spica_0379 IPR014724 RNA polymerase Rpb2, OB-fold Spica_0379 IPR007644 RNA polymerase, beta subunit, protrusion Spica_0379 IPR007642 RNA polymerase Rpb2, domain 2 Spica_0379 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type Spica_0379 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain Spica_0379 IPR042107 DNA-directed RNA polymerase, beta subunit, external 1 domain superfamily Spica_0379 IPR015712 DNA-directed RNA polymerase, subunit 2 Spica_0380 IPR038120 RNA polymerase Rpb1, funnel domain superfamily Spica_0380 IPR007081 RNA polymerase Rpb1, domain 5 Spica_0380 IPR007083 RNA polymerase Rpb1, domain 4 Spica_0380 IPR042102 RNA polymerase Rpb1, domain 3 superfamily Spica_0380 IPR007066 RNA polymerase Rpb1, domain 3 Spica_0380 IPR012754 DNA-directed RNA polymerase, subunit beta-prime Spica_0380 IPR000722 RNA polymerase, alpha subunit Spica_0380 IPR006592 RNA polymerase, N-terminal Spica_0380 IPR007080 RNA polymerase Rpb1, domain 1 Spica_0381 IPR005679 Ribosomal protein S12, bacterial-type Spica_0381 IPR006032 Ribosomal protein S12/S23 Spica_0381 IPR012340 Nucleic acid-binding, OB-fold Spica_0382 IPR005717 Ribosomal protein S7, bacterial/organellar-type Spica_0382 IPR020606 Ribosomal protein S7, conserved site Spica_0382 IPR023798 Ribosomal protein S7 domain Spica_0382 IPR036823 Ribosomal protein S7 domain superfamily Spica_0382 IPR000235 Ribosomal protein S5/S7 Spica_0383 IPR009000 Translation protein, beta-barrel domain superfamily Spica_0383 IPR041709 Elongation factor Tu (EF-Tu), GTP-binding domain Spica_0383 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal Spica_0383 IPR000795 Transcription factor, GTP-binding domain Spica_0383 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal Spica_0383 IPR033720 Elongation factor Tu, domain 2 Spica_0383 IPR031157 Tr-type G domain, conserved site Spica_0383 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0383 IPR005225 Small GTP-binding protein domain Spica_0383 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle Spica_0383 IPR004161 Translation elongation factor EFTu-like, domain 2 Spica_0384 IPR036838 Ribosomal protein S10 domain superfamily Spica_0384 IPR027486 Ribosomal protein S10 domain Spica_0384 IPR018268 Ribosomal protein S10, conserved site Spica_0384 IPR001848 Ribosomal protein S10 Spica_0385 IPR019926 Ribosomal protein L3, conserved site Spica_0385 IPR009000 Translation protein, beta-barrel domain superfamily Spica_0385 IPR019927 Ribosomal protein L3, bacterial/organelle-type Spica_0385 IPR000597 Ribosomal protein L3 Spica_0386 IPR023574 Ribosomal protein L4 domain superfamily Spica_0386 IPR013005 50S ribosomal protein uL4 Spica_0386 IPR002136 Ribosomal protein L4/L1e Spica_0387 IPR001014 Ribosomal protein L23/L25, conserved site Spica_0387 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily Spica_0387 IPR012678 Ribosomal protein L23/L15e core domain superfamily Spica_0387 IPR013025 Ribosomal protein L25/L23 Spica_0388 IPR022669 Ribosomal protein L2, C-terminal Spica_0388 IPR005880 Ribosomal protein L2, bacterial/organellar-type Spica_0388 IPR014722 Ribosomal protein L2, domain 2 Spica_0388 IPR012340 Nucleic acid-binding, OB-fold Spica_0388 IPR022666 Ribosomal Proteins L2, RNA binding domain Spica_0388 IPR002171 Ribosomal protein L2 Spica_0388 IPR014726 Ribosomal protein L2, domain 3 Spica_0388 IPR008991 Translation protein SH3-like domain superfamily Spica_0389 IPR023575 Ribosomal protein S19, superfamily Spica_0389 IPR020934 Ribosomal protein S19 conserved site Spica_0389 IPR002222 Ribosomal protein S19/S15 Spica_0389 IPR005732 Ribosomal protein S19, bacterial-type Spica_0390 IPR001063 Ribosomal protein L22/L17 Spica_0390 IPR018260 Ribosomal protein L22/L17, conserved site Spica_0390 IPR036394 Ribosomal protein L22/L17 superfamily Spica_0390 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type Spica_0391 IPR015946 K homology domain-like, alpha/beta Spica_0391 IPR005704 Ribosomal protein S3, bacterial-type Spica_0391 IPR004044 K Homology domain, type 2 Spica_0391 IPR036419 Ribosomal protein S3, C-terminal domain superfamily Spica_0391 IPR009019 K homology domain superfamily, prokaryotic type Spica_0391 IPR004087 K Homology domain Spica_0391 IPR018280 Ribosomal protein S3, conserved site Spica_0391 IPR001351 Ribosomal protein S3, C-terminal Spica_0392 IPR016180 Ribosomal protein L10e/L16 Spica_0392 IPR036920 Ribosomal protein L10e/L16 superfamily Spica_0392 IPR000114 Ribosomal protein L16 Spica_0392 IPR020798 Ribosomal protein L16, conserved site Spica_0393 IPR001854 Ribosomal protein L29/L35 Spica_0393 IPR036049 Ribosomal protein L29/L35 superfamily Spica_0394 IPR012340 Nucleic acid-binding, OB-fold Spica_0394 IPR019984 30S ribosomal protein S17 Spica_0394 IPR019979 Ribosomal protein S17, conserved site Spica_0394 IPR000266 Ribosomal protein S17/S11 Spica_0395 IPR019972 Ribosomal protein L14P, conserved site Spica_0395 IPR005745 Ribosomal protein L14P, bacterial-type Spica_0395 IPR000218 Ribosomal protein L14P Spica_0395 IPR036853 Ribosomal protein L14 superfamily Spica_0396 IPR005824 KOW Spica_0396 IPR014722 Ribosomal protein L2, domain 2 Spica_0396 IPR003256 Ribosomal protein L24 Spica_0396 IPR005825 Ribosomal protein L24/L26, conserved site Spica_0396 IPR008991 Translation protein SH3-like domain superfamily Spica_0396 IPR041988 Ribosomal Protein L26/L24, KOW domain Spica_0397 IPR022803 Ribosomal protein L5 domain superfamily Spica_0397 IPR020929 Ribosomal protein L5, conserved site Spica_0397 IPR031310 Ribosomal protein L5, N-terminal Spica_0397 IPR031309 Ribosomal protein L5, C-terminal Spica_0397 IPR020930 Ribosomal protein L5, bacterial-type Spica_0397 IPR002132 Ribosomal protein L5 Spica_0398 IPR018271 Ribosomal protein S14, conserved site Spica_0398 IPR001209 Ribosomal protein S14 Spica_0398 IPR023053 Ribosomal protein S14, type Z Spica_0399 IPR000630 Ribosomal protein S8 Spica_0399 IPR035987 Ribosomal protein S8 superfamily Spica_0400 IPR020040 Ribosomal protein L6, alpha-beta domain Spica_0400 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily Spica_0400 IPR000702 Ribosomal protein L6 Spica_0400 IPR019906 Ribosomal protein L6, bacterial-type Spica_0400 IPR002358 Ribosomal protein L6, conserved site Spica_0401 IPR005484 Ribosomal protein L18 Spica_0401 IPR004389 Ribosomal protein L18, bacterial-type Spica_0402 IPR013810 Ribosomal protein S5, N-terminal Spica_0402 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_0402 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0402 IPR005324 Ribosomal protein S5, C-terminal Spica_0402 IPR005712 Ribosomal protein S5, bacterial-type Spica_0402 IPR000851 Ribosomal protein S5 Spica_0402 IPR018192 Ribosomal protein S5, N-terminal, conserved site Spica_0403 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily Spica_0403 IPR005996 Ribosomal protein L30, bacterial-type Spica_0403 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain Spica_0403 IPR018038 Ribosomal protein L30, conserved site Spica_0404 IPR001196 Ribosomal protein L15, conserved site Spica_0404 IPR036227 Ribosomal L18e/L15P superfamily Spica_0404 IPR021131 Ribosomal protein L18e/L15P Spica_0404 IPR030878 Ribosomal protein L15 Spica_0404 IPR005749 Ribosomal protein L15, bacterial-type Spica_0405 IPR026593 Protein translocase subunit SecY Spica_0405 IPR023201 SecY domain superfamily Spica_0405 IPR030659 SecY conserved site Spica_0405 IPR002208 SecY/SEC61-alpha family Spica_0406 IPR000473 Ribosomal protein L36 Spica_0406 IPR035977 Ribosomal protein L36 superfamily Spica_0407 IPR019980 Ribosomal protein S13, bacterial-type Spica_0407 IPR001892 Ribosomal protein S13 Spica_0407 IPR018269 Ribosomal protein S13, conserved site Spica_0407 IPR027437 30s ribosomal protein S13, C-terminal Spica_0407 IPR010979 Ribosomal protein S13-like, H2TH Spica_0408 IPR036967 Ribosomal protein S11 superfamily Spica_0408 IPR001971 Ribosomal protein S11 Spica_0408 IPR019981 Ribosomal protein S11, bacterial-type Spica_0409 IPR001912 Ribosomal protein S4/S9, N-terminal Spica_0409 IPR022801 Ribosomal protein S4/S9 Spica_0409 IPR005709 Ribosomal protein S4, bacterial-type Spica_0409 IPR036986 RNA-binding S4 domain superfamily Spica_0409 IPR002942 RNA-binding S4 domain Spica_0410 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type Spica_0410 IPR011773 DNA-directed RNA polymerase, alpha subunit Spica_0410 IPR036643 DNA-directed RNA polymerase, insert domain superfamily Spica_0410 IPR011260 RNA polymerase, alpha subunit, C-terminal Spica_0410 IPR036603 RNA polymerase, RBP11-like subunit Spica_0410 IPR011262 DNA-directed RNA polymerase, insert domain Spica_0411 IPR036373 Ribosomal protein L17 superfamily Spica_0411 IPR000456 Ribosomal protein L17 Spica_0413 IPR028081 Leucine-binding protein domain Spica_0413 IPR028082 Periplasmic binding protein-like I Spica_0413 IPR000709 Leu/Ile/Val-binding protein Spica_0414 IPR001851 ABC transporter, permease Spica_0415 IPR021807 High-affinity branched-chain amino acid transport system permease, LivHM, N-terminal Spica_0415 IPR001851 ABC transporter, permease Spica_0416 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Spica_0416 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0416 IPR003439 ABC transporter-like Spica_0416 IPR003593 AAA+ ATPase domain Spica_0416 IPR017871 ABC transporter, conserved site Spica_0417 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0417 IPR017871 ABC transporter, conserved site Spica_0417 IPR003439 ABC transporter-like Spica_0417 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein Spica_0417 IPR003593 AAA+ ATPase domain Spica_0418 IPR000644 CBS domain Spica_0418 IPR013785 Aldolase-type TIM barrel Spica_0418 IPR001093 IMP dehydrogenase/GMP reductase Spica_0418 IPR015875 IMP dehydrogenase / GMP reductase, conserved site Spica_0418 IPR005990 Inosine-5'-monophosphate dehydrogenase Spica_0419 IPR004811 RelA/SpoT family Spica_0419 IPR003607 HD/PDEase domain Spica_0419 IPR012675 Beta-grasp domain superfamily Spica_0419 IPR007685 RelA/SpoT Spica_0419 IPR012676 TGS-like Spica_0419 IPR033655 RelA, TGS domain Spica_0419 IPR004095 TGS Spica_0420 IPR002052 DNA methylase, N-6 adenine-specific, conserved site Spica_0420 IPR004556 Methyltransferase HemK-like Spica_0420 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0420 IPR040758 Release factor glutamine methyltransferase, N-terminal domain Spica_0420 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific Spica_0420 IPR007848 Methyltransferase small domain Spica_0421 IPR005139 Peptide chain release factor Spica_0421 IPR000352 Peptide chain release factor class I Spica_0421 IPR004373 Peptide chain release factor 1 Spica_0422 IPR003921 Cellulose synthase, subunit C Spica_0422 IPR019734 Tetratricopeptide repeat Spica_0422 IPR011990 Tetratricopeptide-like helical domain superfamily Spica_0422 IPR013026 Tetratricopeptide repeat-containing domain Spica_0422 IPR008410 Cellulose synthase operon C, C-terminal Spica_0423 IPR028893 Adenosine deaminase Spica_0423 IPR001365 Adenosine/AMP deaminase domain Spica_0423 IPR006330 Adenosine/adenine deaminase Spica_0423 IPR032466 Metal-dependent hydrolase Spica_0427 IPR027409 GroEL-like apical domain superfamily Spica_0427 IPR001844 Chaperonin Cpn60 Spica_0427 IPR027413 GroEL-like equatorial domain superfamily Spica_0427 IPR018370 Chaperonin Cpn60, conserved site Spica_0427 IPR002423 Chaperonin Cpn60/TCP-1 family Spica_0427 IPR027410 TCP-1-like chaperonin intermediate domain superfamily Spica_0428 IPR029009 Allosteric substrate binding domain superfamily Spica_0428 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit Spica_0428 IPR005131 Serine dehydratase beta chain Spica_0428 IPR002912 ACT domain Spica_0429 IPR005130 Serine dehydratase-like, alpha subunit Spica_0429 IPR004642 Serine dehydratase, alpha subunit Spica_0430 IPR000683 Oxidoreductase, N-terminal Spica_0430 IPR036291 NAD(P)-binding domain superfamily Spica_0430 IPR004104 Oxidoreductase, C-terminal Spica_0431 IPR013785 Aldolase-type TIM barrel Spica_0431 IPR006218 DAHP synthetase I/KDSA Spica_0431 IPR006219 DHAP synthase, class 1 Spica_0432 IPR012337 Ribonuclease H-like superfamily Spica_0432 IPR002156 Ribonuclease H domain Spica_0432 IPR036397 Ribonuclease H superfamily Spica_0432 IPR022892 Ribonuclease HI Spica_0433 IPR017154 Uncharacterised conserved protein UCP037246 Spica_0433 IPR003173 Transcriptional coactivator p15 (PC4) Spica_0439 IPR001333 Peptidase M32, carboxypeptidase Taq Spica_0442 IPR000462 CDP-alcohol phosphatidyltransferase Spica_0442 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Spica_0444 IPR017853 Glycoside hydrolase superfamily Spica_0444 IPR003385 Glycoside hydrolase, family 77 Spica_0446 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0446 IPR005517 Translation elongation factor EFG/EF2, domain IV Spica_0446 IPR004540 Translation elongation factor EFG/EF2 Spica_0446 IPR009000 Translation protein, beta-barrel domain superfamily Spica_0446 IPR000795 Transcription factor, GTP-binding domain Spica_0446 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0446 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_0446 IPR031157 Tr-type G domain, conserved site Spica_0446 IPR004161 Translation elongation factor EFTu-like, domain 2 Spica_0446 IPR005225 Small GTP-binding protein domain Spica_0446 IPR000640 Elongation factor EFG, domain V-like Spica_0446 IPR041095 Elongation Factor G, domain II Spica_0446 IPR035647 EF-G domain III/V-like Spica_0446 IPR009022 Elongation factor G, domain III Spica_0449 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0449 IPR001977 Dephospho-CoA kinase Spica_0450 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal Spica_0450 IPR001098 DNA-directed DNA polymerase, family A, palm domain Spica_0450 IPR018320 DNA polymerase 1 Spica_0450 IPR002298 DNA polymerase A Spica_0450 IPR013520 Exonuclease, RNase T/DNA polymerase III Spica_0450 IPR008918 Helix-hairpin-helix motif, class 2 Spica_0450 IPR012337 Ribonuclease H-like superfamily Spica_0450 IPR002562 3'-5' exonuclease domain Spica_0450 IPR036397 Ribonuclease H superfamily Spica_0450 IPR019760 DNA-directed DNA polymerase, family A, conserved site Spica_0450 IPR036279 5'-3' exonuclease, C-terminal domain superfamily Spica_0450 IPR020045 DNA polymerase I-like, H3TH domain Spica_0450 IPR029060 PIN-like domain superfamily Spica_0450 IPR002421 5'-3' exonuclease, N-terminal Spica_0451 IPR036679 FlgN-like superfamily Spica_0452 IPR036584 Flagellar protein FliS superfamily Spica_0452 IPR003713 Flagellar protein FliS Spica_0453 IPR036554 GHMP kinase, C-terminal domain superfamily Spica_0453 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_0453 IPR006206 Mevalonate/galactokinase Spica_0453 IPR000705 Galactokinase Spica_0453 IPR022963 Galactokinase, bacterial Spica_0453 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0453 IPR006203 GHMP kinase, ATP-binding, conserved site Spica_0453 IPR006204 GHMP kinase N-terminal domain Spica_0453 IPR019741 Galactokinase, conserved site Spica_0453 IPR019539 Galactokinase galactose-binding domain Spica_0453 IPR013750 GHMP kinase, C-terminal domain Spica_0454 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal Spica_0454 IPR001937 Galactose-1-phosphate uridyl transferase, class I Spica_0454 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site Spica_0454 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal Spica_0454 IPR036265 HIT-like superfamily Spica_0456 IPR010920 LSM domain superfamily Spica_0456 IPR006685 Mechanosensitive ion channel MscS Spica_0456 IPR008910 Conserved TM helix Spica_0456 IPR023408 Mechanosensitive ion channel MscS domain superfamily Spica_0456 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 Spica_0456 IPR006686 Mechanosensitive ion channel MscS, conserved site Spica_0456 IPR011066 Mechanosensitive ion channel MscS, C-terminal Spica_0457 IPR000642 Peptidase M41 Spica_0457 IPR037219 Peptidase M41-like Spica_0457 IPR003959 ATPase, AAA-type, core Spica_0457 IPR005936 Peptidase, FtsH Spica_0457 IPR003960 ATPase, AAA-type, conserved site Spica_0457 IPR003593 AAA+ ATPase domain Spica_0457 IPR041569 AAA ATPase, AAA+ lid domain Spica_0457 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0459 IPR001890 RNA-binding, CRM domain Spica_0459 IPR017924 RNA-binding protein YhbY Spica_0459 IPR035920 YhbY-like superfamily Spica_0462 IPR013848 Methylthiotransferase, N-terminal Spica_0462 IPR007197 Radical SAM Spica_0462 IPR041582 RimO, TRAM domain Spica_0462 IPR005840 Ribosomal protein S12 methylthiotransferase RimO Spica_0462 IPR038135 Methylthiotransferase, N-terminal domain superfamily Spica_0462 IPR020612 Methylthiotransferase, conserved site Spica_0462 IPR005839 Methylthiotransferase Spica_0462 IPR006638 Elp3/MiaB/NifB Spica_0462 IPR023404 Radical SAM, alpha/beta horseshoe Spica_0463 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0463 IPR000212 DNA helicase, UvrD/REP type Spica_0463 IPR014017 UvrD-like DNA helicase, C-terminal Spica_0463 IPR013986 DExx box DNA helicase domain superfamily Spica_0463 IPR014016 UvrD-like helicase, ATP-binding domain Spica_0463 IPR005751 ATP-dependent DNA helicase PcrA Spica_0463 IPR034739 UvrD/AddA helicase, N-terminal Spica_0467 IPR036899 Ribosomal protein L13 superfamily Spica_0467 IPR005822 Ribosomal protein L13 Spica_0467 IPR005823 Ribosomal protein L13, bacterial-type Spica_0467 IPR023563 Ribosomal protein L13, conserved site Spica_0468 IPR020574 Ribosomal protein S9, conserved site Spica_0468 IPR023035 Ribosomal protein S9, bacterial/plastid Spica_0468 IPR000754 Ribosomal protein S9 Spica_0468 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_0468 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0469 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0469 IPR003783 Regulatory protein RecX Spica_0470 IPR011006 CheY-like superfamily Spica_0470 IPR001789 Signal transduction response regulator, receiver domain Spica_0470 IPR037522 HD-GYP domain Spica_0470 IPR003607 HD/PDEase domain Spica_0471 IPR011006 CheY-like superfamily Spica_0471 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_0471 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0471 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0471 IPR005467 Histidine kinase domain Spica_0471 IPR001789 Signal transduction response regulator, receiver domain Spica_0471 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_0471 IPR013656 PAS fold-4 Spica_0471 IPR035965 PAS domain superfamily Spica_0471 IPR000014 PAS domain Spica_0471 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_0472 IPR001792 Acylphosphatase-like domain Spica_0472 IPR028627 Acylphosphatase, bacteria Spica_0472 IPR017968 Acylphosphatase, conserved site Spica_0472 IPR020456 Acylphosphatase Spica_0472 IPR036046 Acylphosphatase-like domain superfamily Spica_0473 IPR037005 S-ribosylhomocysteinase (LuxS) superfamily Spica_0473 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like Spica_0473 IPR003815 S-ribosylhomocysteinase (LuxS) Spica_0474 IPR000845 Nucleoside phosphorylase domain Spica_0474 IPR035994 Nucleoside phosphorylase superfamily Spica_0474 IPR010049 MTA/SAH nucleosidase Spica_0478 IPR000160 GGDEF domain Spica_0478 IPR013515 Phytochrome, central region Spica_0478 IPR001294 Phytochrome Spica_0478 IPR029016 GAF-like domain superfamily Spica_0478 IPR029787 Nucleotide cyclase Spica_0478 IPR016132 Phytochrome chromophore attachment domain Spica_0478 IPR035919 EAL domain superfamily Spica_0478 IPR003018 GAF domain Spica_0478 IPR001633 EAL domain Spica_0481 IPR011856 tRNA endonuclease-like domain superfamily Spica_0481 IPR003509 Uncharacterised protein family UPF0102 Spica_0481 IPR011335 Restriction endonuclease type II-like Spica_0482 IPR006674 HD domain Spica_0482 IPR037522 HD-GYP domain Spica_0482 IPR006675 HDIG domain Spica_0482 IPR021812 Protein of unknown function DUF3391 Spica_0482 IPR003607 HD/PDEase domain Spica_0485 IPR038657 Ribosomal protein L19 superfamily Spica_0485 IPR001857 Ribosomal protein L19 Spica_0485 IPR018257 Ribosomal protein L19, conserved site Spica_0485 IPR008991 Translation protein SH3-like domain superfamily Spica_0486 IPR029028 Alpha/beta knot methyltransferases Spica_0486 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal Spica_0486 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spica_0486 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain Spica_0486 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria Spica_0487 IPR009000 Translation protein, beta-barrel domain superfamily Spica_0487 IPR002676 RimM, N-terminal Spica_0487 IPR011033 PRC-barrel-like superfamily Spica_0487 IPR036976 RimM, N-terminal domain superfamily Spica_0487 IPR011961 16S rRNA processing protein RimM Spica_0487 IPR027275 PRC-barrel domain Spica_0488 IPR009019 K homology domain superfamily, prokaryotic type Spica_0488 IPR015946 K homology domain-like, alpha/beta Spica_0488 IPR020627 Uncharacterised protein family UPF0109 Spica_0489 IPR000307 Ribosomal protein S16 Spica_0489 IPR023803 Ribosomal protein S16 domain superfamily Spica_0490 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain Spica_0490 IPR004780 Signal recognition particle protein Spica_0490 IPR004125 Signal recognition particle, SRP54 subunit, M-domain Spica_0490 IPR013822 Signal recognition particle SRP54, helical bundle Spica_0490 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily Spica_0490 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0490 IPR003593 AAA+ ATPase domain Spica_0490 IPR042101 Signal recognition particle SRP54, N-terminal domain superfamily Spica_0490 IPR022941 Signal recognition particle, SRP54 subunit Spica_0491 IPR013328 6-phosphogluconate dehydrogenase, domain 2 Spica_0491 IPR036291 NAD(P)-binding domain superfamily Spica_0491 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal Spica_0491 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily Spica_0491 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent Spica_0491 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal Spica_0493 IPR023005 Nucleoside diphosphate kinase, active site Spica_0493 IPR036850 Nucleoside diphosphate kinase-like domain superfamily Spica_0493 IPR001564 Nucleoside diphosphate kinase Spica_0493 IPR034907 Nucleoside diphosphate kinase-like domain Spica_0494 IPR020103 Pseudouridine synthase, catalytic domain superfamily Spica_0494 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain Spica_0494 IPR001406 Pseudouridine synthase I, TruA Spica_0494 IPR020095 Pseudouridine synthase I, TruA, C-terminal Spica_0495 IPR002305 Aminoacyl-tRNA synthetase, class Ic Spica_0495 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site Spica_0495 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0495 IPR002306 Tryptophan-tRNA ligase Spica_0495 IPR024109 Tryptophan-tRNA ligase, bacterial-type Spica_0495 IPR036913 YegP-like superfamily Spica_0497 IPR024258 Protein of unknown function DUF3798 Spica_0498 IPR001789 Signal transduction response regulator, receiver domain Spica_0498 IPR037522 HD-GYP domain Spica_0498 IPR011006 CheY-like superfamily Spica_0498 IPR003607 HD/PDEase domain Spica_0499 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_0499 IPR001650 Helicase, C-terminal Spica_0499 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0499 IPR038718 SNF2-like, N-terminal domain superfamily Spica_0499 IPR000330 SNF2-related, N-terminal domain Spica_0507 IPR036291 NAD(P)-binding domain superfamily Spica_0507 IPR001509 NAD-dependent epimerase/dehydratase Spica_0508 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_0508 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase Spica_0508 IPR015424 Pyridoxal phosphate-dependent transferase Spica_0508 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_0510 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Spica_0510 IPR013785 Aldolase-type TIM barrel Spica_0510 IPR020007 N-acetylneuraminate synthase Spica_0510 IPR013132 N-acetylneuraminic acid synthase, N-terminal Spica_0510 IPR013974 SAF domain Spica_0510 IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily Spica_0511 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like Spica_0511 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Spica_0511 IPR020004 UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing Spica_0512 IPR005835 Nucleotidyl transferase domain Spica_0512 IPR037538 UTP--glucose-1-phosphate uridylyltransferase, cyanobacteria Spica_0512 IPR029044 Nucleotide-diphospho-sugar transferases Spica_0514 IPR003329 Acylneuraminate cytidylyltransferase Spica_0514 IPR029044 Nucleotide-diphospho-sugar transferases Spica_0515 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0515 IPR036291 NAD(P)-binding domain superfamily Spica_0521 IPR036526 Carbon-nitrogen hydrolase superfamily Spica_0521 IPR003010 Carbon-nitrogen hydrolase Spica_0521 IPR014445 Glutamine-dependent NAD(+) synthetase Spica_0521 IPR022310 NAD/GMP synthase Spica_0521 IPR003694 NAD(+) synthetase Spica_0521 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0522 IPR029062 Class I glutamine amidotransferase-like Spica_0522 IPR017926 Glutamine amidotransferase Spica_0522 IPR010139 Imidazole glycerol phosphate synthase, subunit H Spica_0523 IPR004651 Histidine biosynthesis, HisF Spica_0523 IPR006062 Histidine biosynthesis Spica_0523 IPR013785 Aldolase-type TIM barrel Spica_0523 IPR011060 Ribulose-phosphate binding barrel Spica_0524 IPR013692 UDP-glucose 4-epimerase CapD, C-terminal domain Spica_0524 IPR036291 NAD(P)-binding domain superfamily Spica_0524 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain Spica_0525 IPR036291 NAD(P)-binding domain superfamily Spica_0525 IPR011051 RmlC-like cupin domain superfamily Spica_0525 IPR014710 RmlC-like jelly roll fold Spica_0525 IPR001509 NAD-dependent epimerase/dehydratase Spica_0526 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like Spica_0526 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Spica_0528 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form Spica_0528 IPR005835 Nucleotidyl transferase domain Spica_0528 IPR029044 Nucleotide-diphospho-sugar transferases Spica_0529 IPR011051 RmlC-like cupin domain superfamily Spica_0529 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related Spica_0529 IPR014710 RmlC-like jelly roll fold Spica_0530 IPR036291 NAD(P)-binding domain superfamily Spica_0530 IPR029903 RmlD-like substrate binding domain Spica_0530 IPR005913 dTDP-4-dehydrorhamnose reductase family Spica_0535 IPR036291 NAD(P)-binding domain superfamily Spica_0535 IPR016040 NAD(P)-binding domain Spica_0535 IPR005888 dTDP-glucose 4,6-dehydratase Spica_0540 IPR017871 ABC transporter, conserved site Spica_0540 IPR015861 ABC transporter, ribose import, RbsA Spica_0540 IPR003593 AAA+ ATPase domain Spica_0540 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0540 IPR003439 ABC transporter-like Spica_0544 IPR004633 Na/Pi-cotransporter II-related/YqeW-like protein Spica_0544 IPR003841 Sodium-dependent phosphate transport protein Spica_0545 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_0545 IPR001279 Metallo-beta-lactamase Spica_0547 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily Spica_0547 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain Spica_0549 IPR020810 Enolase, C-terminal TIM barrel domain Spica_0549 IPR020809 Enolase, conserved site Spica_0549 IPR036849 Enolase-like, C-terminal domain superfamily Spica_0549 IPR020811 Enolase, N-terminal Spica_0549 IPR029017 Enolase-like, N-terminal Spica_0549 IPR000941 Enolase Spica_0553 IPR000537 UbiA prenyltransferase family Spica_0553 IPR026046 UbiA prenyltransferase domain containing protein 1 Spica_0553 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase Spica_0554 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0554 IPR022066 Signal transduction histidine kinase, N-terminal Spica_0554 IPR005467 Histidine kinase domain Spica_0554 IPR035965 PAS domain superfamily Spica_0554 IPR038424 Signal transduction histidine kinase, N-terminal domain superfamily Spica_0554 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0554 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_0556 IPR001423 Lysophospholipase patatin, conserved site Spica_0556 IPR002641 Patatin-like phospholipase domain Spica_0556 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Spica_0557 IPR042122 Serine acetyltransferase, N-terminal domain superfamily Spica_0557 IPR001451 Hexapeptide repeat Spica_0557 IPR011004 Trimeric LpxA-like superfamily Spica_0559 IPR004044 K Homology domain, type 2 Spica_0559 IPR005662 GTP-binding protein Era Spica_0559 IPR006073 GTP binding domain Spica_0559 IPR015946 K homology domain-like, alpha/beta Spica_0559 IPR030388 Era-type guanine nucleotide-binding (G) domain Spica_0559 IPR005225 Small GTP-binding protein domain Spica_0559 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0559 IPR009019 K homology domain superfamily, prokaryotic type Spica_0560 IPR023214 HAD superfamily Spica_0560 IPR011863 Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein Spica_0560 IPR036412 HAD-like superfamily Spica_0561 IPR002317 Serine-tRNA ligase, type1 Spica_0561 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm Spica_0561 IPR042103 Serine-tRNA synthetase, type1, N-terminal domain superfamily Spica_0561 IPR033729 Serine-tRNA ligase catalytic core domain Spica_0561 IPR006195 Aminoacyl-tRNA synthetase, class II Spica_0561 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) Spica_0561 IPR015866 Serine-tRNA synthetase, type1, N-terminal Spica_0562 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain Spica_0562 IPR013196 Helix-turn-helix, type 11 Spica_0562 IPR036390 Winged helix DNA-binding domain superfamily Spica_0562 IPR004409 Biotin operon repressor, helix-turn-helix domain Spica_0562 IPR030855 Bifunctional ligase/repressor BirA Spica_0562 IPR004408 Biotin--acetyl-CoA-carboxylase ligase Spica_0562 IPR003142 Biotin protein ligase, C-terminal Spica_0562 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0562 IPR008988 Transcriptional repressor, C-terminal Spica_0565 IPR010935 SMCs flexible hinge Spica_0565 IPR024704 Structural maintenance of chromosomes protein Spica_0565 IPR003395 RecF/RecN/SMC, N-terminal Spica_0565 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0565 IPR036277 SMCs flexible hinge superfamily Spica_0565 IPR011890 Structural maintenance of chromosomes protein, prokaryotic Spica_0569 IPR029060 PIN-like domain superfamily Spica_0569 IPR022907 VapC family Spica_0569 IPR002716 PIN domain Spica_0570 IPR002071 Thermonuclease active site Spica_0570 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Spica_0570 IPR035437 SNase-like, OB-fold superfamily Spica_0571 IPR003439 ABC transporter-like Spica_0571 IPR003593 AAA+ ATPase domain Spica_0571 IPR032781 ABC-transporter extension domain Spica_0571 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0572 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_0572 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0572 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site Spica_0572 IPR023554 ATP-dependent RNA helicase RhlB type Spica_0572 IPR014014 RNA helicase, DEAD-box type, Q motif Spica_0572 IPR001650 Helicase, C-terminal Spica_0572 IPR011545 DEAD/DEAH box helicase domain Spica_0577 IPR002068 Alpha crystallin/Hsp20 domain Spica_0577 IPR008978 HSP20-like chaperone Spica_0578 IPR034505 Anaerobic coproporphyrinogen-III oxidase Spica_0578 IPR023404 Radical SAM, alpha/beta horseshoe Spica_0578 IPR007197 Radical SAM Spica_0578 IPR004559 Heme chaperone HemW-like Spica_0578 IPR006638 Elp3/MiaB/NifB Spica_0578 IPR010723 HemN, C-terminal Spica_0579 IPR023861 Chloride channel, ClcA Spica_0579 IPR001807 Chloride channel, voltage gated Spica_0579 IPR014743 Chloride channel, core Spica_0580 IPR033380 Glutamate-aspartate symport protein GltP/GltT Spica_0580 IPR034703 Proton/glutamate-aspartate symporter GltP Spica_0580 IPR036458 Sodium:dicarboxylate symporter superfamily Spica_0580 IPR001991 Sodium:dicarboxylate symporter Spica_0580 IPR018107 Sodium:dicarboxylate symporter, conserved site Spica_0582 IPR001647 DNA-binding HTH domain, TetR-type Spica_0582 IPR009057 Homeobox-like domain superfamily Spica_0582 IPR023772 DNA-binding HTH domain, TetR-type, conserved site Spica_0583 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0583 IPR000241 Putative RNA methylase domain Spica_0583 IPR004114 THUMP domain Spica_0583 IPR002052 DNA methylase, N-6 adenine-specific, conserved site Spica_0584 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0584 IPR040739 RlmM ferredoxin-like domain Spica_0584 IPR011224 Ribosomal RNA large subunit methyltransferase M Spica_0584 IPR002877 Ribosomal RNA methyltransferase FtsJ domain Spica_0593 IPR017587 Putative selenium-dependent hydroxylase accessory protein YqeC Spica_0593 IPR036565 Mur-like, catalytic domain superfamily Spica_0596 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel Spica_0596 IPR005084 Carbohydrate binding module family 6 Spica_0596 IPR001137 Glycoside hydrolase family 11 Spica_0596 IPR018208 Glycoside hydrolase family 11, active site 1 Spica_0596 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Spica_0596 IPR013319 Glycoside hydrolase family 11/12 Spica_0596 IPR008979 Galactose-binding-like domain superfamily Spica_0596 IPR033119 Glycoside hydrolase family 11, active site 2 Spica_0596 IPR002509 NodB homology domain Spica_0596 IPR033123 Glycosyl hydrolases family 11 (GH11) domain Spica_0597 IPR012341 Six-hairpin glycosidase-like superfamily Spica_0597 IPR002037 Glycoside hydrolase, family 8 Spica_0597 IPR008928 Six-hairpin glycosidase superfamily Spica_0598 IPR035906 MetI-like superfamily Spica_0598 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0599 IPR035906 MetI-like superfamily Spica_0599 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0601 IPR004628 Mannonate dehydratase Spica_0601 IPR036237 Xylose isomerase-like superfamily Spica_0602 IPR037054 Alpha-glucuronidase, C-terminal domain superfamily Spica_0602 IPR011395 Alpha glucuronidase Spica_0602 IPR005154 Alpha glucuronidase, N-terminal Spica_0602 IPR011099 Glycosyl hydrolase family 67, C-terminal Spica_0602 IPR011100 Glycosyl hydrolase family 67, catalytic domain Spica_0602 IPR029018 Beta-hexosaminidase-like, domain 2 Spica_0602 IPR017853 Glycoside hydrolase superfamily Spica_0603 IPR011658 PA14 domain Spica_0603 IPR037524 PA14/GLEYA domain Spica_0603 IPR013783 Immunoglobulin-like fold Spica_0603 IPR017853 Glycoside hydrolase superfamily Spica_0603 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily Spica_0603 IPR001764 Glycoside hydrolase, family 3, N-terminal Spica_0603 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily Spica_0603 IPR002772 Glycoside hydrolase family 3 C-terminal domain Spica_0603 IPR026891 Fibronectin type III-like domain Spica_0605 IPR020904 Short-chain dehydrogenase/reductase, conserved site Spica_0605 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0605 IPR036291 NAD(P)-binding domain superfamily Spica_0606 IPR008920 Transcription regulator FadR/GntR, C-terminal Spica_0606 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0606 IPR011711 GntR, C-terminal Spica_0606 IPR036390 Winged helix DNA-binding domain superfamily Spica_0606 IPR000524 Transcription regulator HTH, GntR Spica_0609 IPR003781 CoA-binding Spica_0609 IPR005811 ATP-citrate lyase/succinyl-CoA ligase Spica_0609 IPR016102 Succinyl-CoA synthetase-like Spica_0610 IPR009499 Protein of unknown function DUF1116 Spica_0610 IPR024033 Uncharacterised domain superfamily, YlbE Spica_0613 IPR000485 AsnC-type HTH domain Spica_0613 IPR000524 Transcription regulator HTH, GntR Spica_0613 IPR008920 Transcription regulator FadR/GntR, C-terminal Spica_0613 IPR011711 GntR, C-terminal Spica_0613 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0613 IPR036390 Winged helix DNA-binding domain superfamily Spica_0615 IPR005107 CO dehydrogenase flavoprotein, C-terminal Spica_0615 IPR036683 CO dehydrogenase flavoprotein, C-terminal domain superfamily Spica_0615 IPR016166 FAD-binding domain, PCMH-type Spica_0615 IPR036318 FAD-binding, type PCMH-like superfamily Spica_0615 IPR016169 FAD-binding, type PCMH, subdomain 2 Spica_0615 IPR002346 Molybdopterin dehydrogenase, FAD-binding Spica_0617 IPR006043 Xanthine/uracil/vitamin C permease Spica_0617 IPR006042 Xanthine/uracil permease Spica_0617 IPR029935 Uracil permease Spica_0622 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0622 IPR035906 MetI-like superfamily Spica_0623 IPR033403 Domain of unknown function DUF5110 Spica_0623 IPR025887 Glycoside hydrolase family 31, N-terminal domain Spica_0623 IPR030459 Glycosyl hydrolases family 31, conserved site Spica_0623 IPR030458 Glycosyl hydrolases family 31, active site Spica_0623 IPR011013 Galactose mutarotase-like domain superfamily Spica_0623 IPR017853 Glycoside hydrolase superfamily Spica_0623 IPR032513 Alpha-glucosidase, domain of unknown function DUF4968 Spica_0623 IPR013780 Glycosyl hydrolase, all-beta Spica_0623 IPR000322 Glycoside hydrolase family 31 Spica_0624 IPR028082 Periplasmic binding protein-like I Spica_0624 IPR010982 Lambda repressor-like, DNA-binding domain superfamily Spica_0624 IPR000843 LacI-type HTH domain Spica_0624 IPR006377 Catabolite control protein A Spica_0625 IPR031338 KDPG/KHG aldolase, active site 2 Spica_0625 IPR031337 KDPG/KHG aldolase, active site 1 Spica_0625 IPR013785 Aldolase-type TIM barrel Spica_0625 IPR000887 KDPG/KHG aldolase Spica_0627 IPR011051 RmlC-like cupin domain superfamily Spica_0627 IPR014710 RmlC-like jelly roll fold Spica_0627 IPR027449 5-keto-4-deoxyuronate isomerase, N-terminal Spica_0627 IPR021120 KduI/IolB isomerase Spica_0627 IPR007045 5-keto 4-deoxyuronate isomerase Spica_0628 IPR020904 Short-chain dehydrogenase/reductase, conserved site Spica_0628 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_0628 IPR011286 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase Spica_0628 IPR036291 NAD(P)-binding domain superfamily Spica_0629 IPR011991 ArsR-like helix-turn-helix domain Spica_0629 IPR036390 Winged helix DNA-binding domain superfamily Spica_0629 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0629 IPR005471 Transcription regulator IclR, N-terminal Spica_0629 IPR014757 Transcription regulator IclR, C-terminal Spica_0629 IPR029016 GAF-like domain superfamily Spica_0630 IPR003766 Uronate isomerase Spica_0630 IPR032466 Metal-dependent hydrolase Spica_0631 IPR004710 Bile acid:sodium symporter Spica_0631 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 Spica_0631 IPR038770 Sodium/solute symporter superfamily Spica_0632 IPR003313 AraC-type arabinose-binding/dimerisation domain Spica_0632 IPR009057 Homeobox-like domain superfamily Spica_0632 IPR037923 Transcription regulator HTH-like Spica_0632 IPR018062 HTH domain AraC-type, conserved site Spica_0632 IPR020449 Transcription regulator HTH, AraC- type Spica_0632 IPR018060 DNA binding HTH domain, AraC-type Spica_0633 IPR008928 Six-hairpin glycosidase superfamily Spica_0633 IPR012341 Six-hairpin glycosidase-like superfamily Spica_0633 IPR010905 Glycosyl hydrolase, family 88 Spica_0635 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0635 IPR035906 MetI-like superfamily Spica_0636 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0636 IPR035906 MetI-like superfamily Spica_0637 IPR006059 Bacterial extracellular solute-binding protein Spica_0639 IPR039448 Right handed beta helix domain Spica_0639 IPR012334 Pectin lyase fold Spica_0639 IPR011050 Pectin lyase fold/virulence factor Spica_0644 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 Spica_0644 IPR004706 Arsenical-resistance protein Acr3 Spica_0644 IPR038770 Sodium/solute symporter superfamily Spica_0646 IPR011005 Dihydropteroate synthase-like Spica_0646 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0646 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_0646 IPR007202 4Fe-4S domain Spica_0646 IPR010207 Ion-translocating oxidoreductase complex, RnfB/RsxB Spica_0647 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA Spica_0647 IPR003667 NqrDE/RnfAE Spica_0648 IPR010968 Ion-translocating oxidoreductase complex subunit E Spica_0648 IPR003667 NqrDE/RnfAE Spica_0649 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG Spica_0649 IPR007329 FMN-binding Spica_0650 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD Spica_0650 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D Spica_0651 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0651 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_0651 IPR009051 Alpha-helical ferredoxin Spica_0651 IPR010208 Ion-translocating oxidoreductase complex, subunit RnfC/RsxC Spica_0651 IPR019554 Soluble ligand binding domain Spica_0651 IPR026902 RnfC Barrel sandwich hybrid domain Spica_0651 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Spica_0651 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Spica_0654 IPR011606 Branched-chain amino acid transport, permease Spica_0654 IPR004471 Branched-chain amino acid transport, AzlC Spica_0655 IPR008407 Branched-chain amino acid transport, AzlD Spica_0656 IPR003660 HAMP domain Spica_0656 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_0656 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding Spica_0656 IPR029151 Periplasmic sensor-like domain superfamily Spica_0656 IPR033479 Double Cache domain 1 Spica_0657 IPR036249 Thioredoxin-like superfamily Spica_0657 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant Spica_0657 IPR013766 Thioredoxin domain Spica_0657 IPR024706 Peroxiredoxin, AhpC-type Spica_0658 IPR020061 Glutamine-tRNA ligase, alpha-bundle domain superfamily Spica_0658 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site Spica_0658 IPR004514 Glutamine-tRNA synthetase Spica_0658 IPR022861 Glutamine-tRNA ligase, bacterial Spica_0658 IPR000924 Glutamyl/glutaminyl-tRNA synthetase Spica_0658 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain Spica_0658 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain Spica_0658 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Spica_0658 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily Spica_0658 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0659 IPR029066 PLP-binding barrel Spica_0659 IPR002433 Ornithine decarboxylase Spica_0659 IPR000183 Ornithine/DAP/Arg decarboxylase Spica_0659 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Spica_0659 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal Spica_0659 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal Spica_0659 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal Spica_0659 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Spica_0660 IPR035966 Phosphofructokinase superfamily Spica_0660 IPR022953 ATP-dependent 6-phosphofructokinase Spica_0660 IPR011183 Pyrophosphate-dependent phosphofructokinase PfpB Spica_0660 IPR000023 Phosphofructokinase domain Spica_0663 IPR015963 Uridylate kinase, bacteria Spica_0663 IPR011817 Uridylate kinase Spica_0663 IPR001048 Aspartate/glutamate/uridylate kinase Spica_0663 IPR036393 Acetylglutamate kinase-like superfamily Spica_0664 IPR002931 Transglutaminase-like Spica_0664 IPR038765 Papain-like cysteine peptidase superfamily Spica_0667 IPR014284 RNA polymerase sigma-70 like domain Spica_0667 IPR007630 RNA polymerase sigma-70 region 4 Spica_0667 IPR012845 RNA polymerase sigma factor, FliA/WhiG Spica_0667 IPR000943 RNA polymerase sigma-70 Spica_0667 IPR007627 RNA polymerase sigma-70 region 2 Spica_0667 IPR007624 RNA polymerase sigma-70 region 3 Spica_0667 IPR028617 RNA polymerase sigma factor FliA Spica_0667 IPR013325 RNA polymerase sigma factor, region 2 Spica_0667 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_0668 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase Spica_0668 IPR015803 Cysteine-tRNA ligase Spica_0668 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding Spica_0668 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR Spica_0668 IPR032678 tRNA synthetases class I, catalytic domain Spica_0668 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0669 IPR006094 FAD linked oxidase, N-terminal Spica_0669 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal Spica_0669 IPR016166 FAD-binding domain, PCMH-type Spica_0669 IPR036318 FAD-binding, type PCMH-like superfamily Spica_0669 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily Spica_0669 IPR016167 FAD-binding, type PCMH, subdomain 1 Spica_0669 IPR016169 FAD-binding, type PCMH, subdomain 2 Spica_0669 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase Spica_0671 IPR018490 Cyclic nucleotide-binding-like Spica_0671 IPR000595 Cyclic nucleotide-binding domain Spica_0671 IPR012318 Crp-type HTH domain Spica_0671 IPR014710 RmlC-like jelly roll fold Spica_0671 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0671 IPR036390 Winged helix DNA-binding domain superfamily Spica_0675 IPR009875 PilZ domain Spica_0678 IPR002901 Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase-like domain Spica_0679 IPR025657 RadC-like JAB domain Spica_0679 IPR001405 Uncharacterised protein family UPF0758 Spica_0679 IPR020891 Uncharacterised protein family UPF0758, conserved site Spica_0679 IPR037518 MPN domain Spica_0679 IPR010994 RuvA domain 2-like Spica_0680 IPR012347 Ferritin-like Spica_0680 IPR009040 Ferritin-like diiron domain Spica_0680 IPR009078 Ferritin-like superfamily Spica_0680 IPR001519 Ferritin Spica_0680 IPR041719 Ferritin, prokaryotic-type Spica_0680 IPR008331 Ferritin/DPS protein domain Spica_0682 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_0682 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase Spica_0682 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site Spica_0682 IPR004839 Aminotransferase, class I/classII Spica_0682 IPR015424 Pyridoxal phosphate-dependent transferase Spica_0682 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_0683 IPR002852 Uncharacterised protein family UPF0251 Spica_0684 IPR036034 PDZ superfamily Spica_0684 IPR001478 PDZ domain Spica_0684 IPR041489 PDZ domain 6 Spica_0684 IPR011782 Peptidase S1C, Do Spica_0684 IPR009003 Peptidase S1, PA clan Spica_0684 IPR001940 Peptidase S1C Spica_0692 IPR003593 AAA+ ATPase domain Spica_0692 IPR017871 ABC transporter, conserved site Spica_0692 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0692 IPR003439 ABC transporter-like Spica_0693 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted Spica_0694 IPR000014 PAS domain Spica_0694 IPR000700 PAS-associated, C-terminal Spica_0694 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_0694 IPR013767 PAS fold Spica_0694 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_0694 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_0694 IPR005467 Histidine kinase domain Spica_0694 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0694 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0694 IPR003660 HAMP domain Spica_0694 IPR035965 PAS domain superfamily Spica_0696 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_0696 IPR025944 Sigma-54 interaction domain, conserved site Spica_0696 IPR003593 AAA+ ATPase domain Spica_0696 IPR011006 CheY-like superfamily Spica_0696 IPR002197 DNA binding HTH domain, Fis-type Spica_0696 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0696 IPR001789 Signal transduction response regulator, receiver domain Spica_0696 IPR002078 RNA polymerase sigma factor 54 interaction domain Spica_0696 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_0696 IPR009057 Homeobox-like domain superfamily Spica_0697 IPR003339 ABC/ECF transporter, transmembrane component Spica_0697 IPR003593 AAA+ ATPase domain Spica_0697 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0697 IPR003439 ABC transporter-like Spica_0697 IPR017871 ABC transporter, conserved site Spica_0699 IPR004619 Type III pantothenate kinase Spica_0701 IPR041492 Haloacid dehalogenase-like hydrolase Spica_0701 IPR006439 HAD hydrolase, subfamily IA Spica_0701 IPR036412 HAD-like superfamily Spica_0701 IPR037512 Phosphoglycolate phosphatase, prokaryotic Spica_0701 IPR023214 HAD superfamily Spica_0701 IPR023198 Phosphoglycolate phosphatase-like, domain 2 Spica_0701 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic Spica_0702 IPR002177 DNA-binding protein Dps Spica_0702 IPR023188 DNA-binding protein Dps, conserved site Spica_0702 IPR012347 Ferritin-like Spica_0702 IPR009078 Ferritin-like superfamily Spica_0702 IPR008331 Ferritin/DPS protein domain Spica_0706 IPR025501 ATP binding protein MinD Spica_0706 IPR010223 ATP binding protein MinD, bacterial-type Spica_0706 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain Spica_0706 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0707 IPR001789 Signal transduction response regulator, receiver domain Spica_0707 IPR002078 RNA polymerase sigma factor 54 interaction domain Spica_0707 IPR025944 Sigma-54 interaction domain, conserved site Spica_0707 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_0707 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_0707 IPR009057 Homeobox-like domain superfamily Spica_0707 IPR011006 CheY-like superfamily Spica_0707 IPR003593 AAA+ ATPase domain Spica_0707 IPR002197 DNA binding HTH domain, Fis-type Spica_0707 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0708 IPR036249 Thioredoxin-like superfamily Spica_0708 IPR022915 Peroxiredoxin, TDXH subfamily Spica_0708 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant Spica_0708 IPR019479 Peroxiredoxin, C-terminal Spica_0708 IPR013766 Thioredoxin domain Spica_0708 IPR024706 Peroxiredoxin, AhpC-type Spica_0709 IPR003593 AAA+ ATPase domain Spica_0709 IPR003018 GAF domain Spica_0709 IPR009057 Homeobox-like domain superfamily Spica_0709 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0709 IPR002078 RNA polymerase sigma factor 54 interaction domain Spica_0709 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_0709 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_0709 IPR025944 Sigma-54 interaction domain, conserved site Spica_0709 IPR029016 GAF-like domain superfamily Spica_0710 IPR004372 Acetate/propionate kinase Spica_0710 IPR000890 Aliphatic acid kinase, short-chain Spica_0710 IPR023865 Aliphatic acid kinase, short-chain, conserved site Spica_0712 IPR002716 PIN domain Spica_0712 IPR022907 VapC family Spica_0712 IPR029060 PIN-like domain superfamily Spica_0713 IPR006059 Bacterial extracellular solute-binding protein Spica_0714 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0714 IPR035906 MetI-like superfamily Spica_0715 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0715 IPR035906 MetI-like superfamily Spica_0716 IPR017853 Glycoside hydrolase superfamily Spica_0716 IPR013780 Glycosyl hydrolase, all-beta Spica_0716 IPR010720 Alpha-L-arabinofuranosidase, C-terminal Spica_0719 IPR001584 Integrase, catalytic core Spica_0719 IPR012337 Ribonuclease H-like superfamily Spica_0719 IPR036397 Ribonuclease H superfamily Spica_0719 IPR025948 HTH-like domain Spica_0720 IPR035917 YjbQ-like superfamily Spica_0720 IPR001602 Uncharacterised protein family UPF0047 Spica_0721 IPR029039 Flavoprotein-like superfamily Spica_0721 IPR005025 NADPH-dependent FMN reductase-like Spica_0722 IPR013647 Oligopeptidase F, N-terminal domain Spica_0722 IPR042088 Oligoendopeptidase F, C-terminal domain Spica_0722 IPR001567 Peptidase M3A/M3B catalytic domain Spica_0722 IPR004438 Peptidase M3B, oligoendopeptidase F Spica_0723 IPR018299 Alkaline phosphatase, active site Spica_0723 IPR017850 Alkaline-phosphatase-like, core domain superfamily Spica_0723 IPR001952 Alkaline phosphatase Spica_0725 IPR006059 Bacterial extracellular solute-binding protein Spica_0726 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0726 IPR035906 MetI-like superfamily Spica_0727 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0727 IPR035906 MetI-like superfamily Spica_0728 IPR000843 LacI-type HTH domain Spica_0728 IPR028082 Periplasmic binding protein-like I Spica_0728 IPR010982 Lambda repressor-like, DNA-binding domain superfamily Spica_0730 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_0730 IPR001036 Acriflavin resistance protein Spica_0733 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0733 IPR039420 Transcriptional regulatory protein WalR-like Spica_0733 IPR011006 CheY-like superfamily Spica_0733 IPR001867 OmpR/PhoB-type DNA-binding domain Spica_0733 IPR016032 Signal transduction response regulator, C-terminal effector Spica_0733 IPR001789 Signal transduction response regulator, receiver domain Spica_0734 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0734 IPR013767 PAS fold Spica_0734 IPR000014 PAS domain Spica_0734 IPR031967 PhoR, single Cache-like domain Spica_0734 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_0734 IPR035965 PAS domain superfamily Spica_0734 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_0734 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_0734 IPR005467 Histidine kinase domain Spica_0734 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0735 IPR000843 LacI-type HTH domain Spica_0735 IPR010982 Lambda repressor-like, DNA-binding domain superfamily Spica_0735 IPR028082 Periplasmic binding protein-like I Spica_0737 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0737 IPR035906 MetI-like superfamily Spica_0738 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0738 IPR035906 MetI-like superfamily Spica_0739 IPR011013 Galactose mutarotase-like domain superfamily Spica_0739 IPR017853 Glycoside hydrolase superfamily Spica_0739 IPR013780 Glycosyl hydrolase, all-beta Spica_0739 IPR025887 Glycoside hydrolase family 31, N-terminal domain Spica_0739 IPR000322 Glycoside hydrolase family 31 Spica_0741 IPR018170 Aldo/keto reductase, conserved site Spica_0741 IPR020471 Aldo/keto reductase Spica_0741 IPR023210 NADP-dependent oxidoreductase domain Spica_0741 IPR036812 NADP-dependent oxidoreductase domain superfamily Spica_0743 IPR011006 CheY-like superfamily Spica_0743 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0743 IPR035965 PAS domain superfamily Spica_0743 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0743 IPR000700 PAS-associated, C-terminal Spica_0743 IPR013656 PAS fold-4 Spica_0743 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_0743 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_0743 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_0743 IPR001610 PAC motif Spica_0743 IPR000014 PAS domain Spica_0743 IPR001789 Signal transduction response regulator, receiver domain Spica_0743 IPR005467 Histidine kinase domain Spica_0745 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Spica_0745 IPR001647 DNA-binding HTH domain, TetR-type Spica_0745 IPR009057 Homeobox-like domain superfamily Spica_0749 IPR003646 SH3-like domain, bacterial-type Spica_0750 IPR003439 ABC transporter-like Spica_0750 IPR017871 ABC transporter, conserved site Spica_0750 IPR003593 AAA+ ATPase domain Spica_0750 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily Spica_0750 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0750 IPR032781 ABC-transporter extension domain Spica_0750 IPR032524 ABC transporter Uup, C-terminal Spica_0751 IPR005886 UDP-glucose 4-epimerase Spica_0751 IPR036291 NAD(P)-binding domain superfamily Spica_0751 IPR016040 NAD(P)-binding domain Spica_0752 IPR002933 Peptidase M20 Spica_0752 IPR011650 Peptidase M20, dimerisation domain Spica_0752 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site Spica_0752 IPR036264 Bacterial exopeptidase dimerisation domain Spica_0752 IPR005941 Succinyl-diaminopimelate desuccinylase, proteobacteria Spica_0753 IPR036144 RibA-like superfamily Spica_0753 IPR032677 GTP cyclohydrolase II Spica_0753 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB Spica_0753 IPR016299 Riboflavin biosynthesis protein RibBA Spica_0753 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily Spica_0753 IPR000926 GTP cyclohydrolase II, RibA Spica_0754 IPR013785 Aldolase-type TIM barrel Spica_0754 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase Spica_0754 IPR007197 Radical SAM Spica_0755 IPR004821 Cytidyltransferase-like domain Spica_0755 IPR001980 Phosphopantetheine adenylyltransferase Spica_0755 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0756 IPR028082 Periplasmic binding protein-like I Spica_0756 IPR003760 ABC transporter substrate-binding protein PnrA-like Spica_0760 IPR035994 Nucleoside phosphorylase superfamily Spica_0760 IPR018016 Nucleoside phosphorylase, conserved site Spica_0760 IPR004402 Purine nucleoside phosphorylase DeoD-type Spica_0760 IPR000845 Nucleoside phosphorylase domain Spica_0762 IPR002481 Ferric-uptake regulator Spica_0762 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0762 IPR036390 Winged helix DNA-binding domain superfamily Spica_0763 IPR028082 Periplasmic binding protein-like I Spica_0763 IPR010982 Lambda repressor-like, DNA-binding domain superfamily Spica_0763 IPR000843 LacI-type HTH domain Spica_0766 IPR035965 PAS domain superfamily Spica_0766 IPR013767 PAS fold Spica_0766 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_0766 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_0766 IPR000014 PAS domain Spica_0766 IPR005467 Histidine kinase domain Spica_0766 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0766 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0766 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_0766 IPR031967 PhoR, single Cache-like domain Spica_0767 IPR011006 CheY-like superfamily Spica_0767 IPR016032 Signal transduction response regulator, C-terminal effector Spica_0767 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB Spica_0767 IPR001789 Signal transduction response regulator, receiver domain Spica_0767 IPR039420 Transcriptional regulatory protein WalR-like Spica_0767 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0767 IPR001867 OmpR/PhoB-type DNA-binding domain Spica_0768 IPR038078 PhoU-like domain superfamily Spica_0768 IPR028366 Phosphate transport system protein PhoU Spica_0768 IPR026022 PhoU domain Spica_0769 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0769 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0769 IPR003593 AAA+ ATPase domain Spica_0769 IPR004482 Mg chelatase-related protein Spica_0769 IPR025158 Mg chelatase-related protein, C-terminal domain Spica_0769 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_0769 IPR000523 Magnesium chelatase ChlI domain Spica_0770 IPR003141 Polymerase/histidinol phosphatase, N-terminal Spica_0770 IPR016195 Polymerase/histidinol phosphatase-like Spica_0770 IPR004013 PHP domain Spica_0771 IPR032466 Metal-dependent hydrolase Spica_0771 IPR023512 Deaminase MtaD/DadD Spica_0771 IPR011059 Metal-dependent hydrolase, composite domain superfamily Spica_0771 IPR006680 Amidohydrolase-related Spica_0773 IPR018490 Cyclic nucleotide-binding-like Spica_0773 IPR000595 Cyclic nucleotide-binding domain Spica_0773 IPR012318 Crp-type HTH domain Spica_0773 IPR014710 RmlC-like jelly roll fold Spica_0773 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0773 IPR036390 Winged helix DNA-binding domain superfamily Spica_0773 IPR018488 Cyclic nucleotide-binding, conserved site Spica_0774 IPR022066 Signal transduction histidine kinase, N-terminal Spica_0774 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0774 IPR005467 Histidine kinase domain Spica_0774 IPR035965 PAS domain superfamily Spica_0774 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_0774 IPR038424 Signal transduction histidine kinase, N-terminal domain superfamily Spica_0774 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0775 IPR013783 Immunoglobulin-like fold Spica_0775 IPR017853 Glycoside hydrolase superfamily Spica_0775 IPR013780 Glycosyl hydrolase, all-beta Spica_0775 IPR006047 Glycosyl hydrolase, family 13, catalytic domain Spica_0775 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S Spica_0775 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase Spica_0776 IPR036637 Phosphohistidine domain superfamily Spica_0776 IPR015795 Pyruvate kinase, C-terminal Spica_0776 IPR018209 Pyruvate kinase, active site Spica_0776 IPR008279 PEP-utilising enzyme, mobile domain Spica_0776 IPR015806 Pyruvate kinase, insert domain superfamily Spica_0776 IPR040442 Pyruvate kinase-like domain superfamily Spica_0776 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily Spica_0776 IPR036918 Pyruvate kinase, C-terminal domain superfamily Spica_0776 IPR001697 Pyruvate kinase Spica_0776 IPR011037 Pyruvate kinase-like, insert domain superfamily Spica_0776 IPR015793 Pyruvate kinase, barrel Spica_0778 IPR029057 Phosphoribosyltransferase-like Spica_0778 IPR005764 Adenine phosphoribosyl transferase Spica_0778 IPR000836 Phosphoribosyltransferase domain Spica_0781 IPR008909 DALR anticodon binding Spica_0781 IPR035684 Arginyl-tRNA synthetase, catalytic core domain Spica_0781 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily Spica_0781 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site Spica_0781 IPR001278 Arginine-tRNA ligase Spica_0781 IPR005148 Arginyl tRNA synthetase N-terminal domain Spica_0781 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding Spica_0781 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0782 IPR036164 L21-like superfamily Spica_0782 IPR028909 Ribosomal protein L21-like Spica_0782 IPR018258 Ribosomal protein L21, conserved site Spica_0782 IPR001787 Ribosomal protein L21 Spica_0784 IPR018261 Ribosomal protein L27, conserved site Spica_0784 IPR001684 Ribosomal protein L27 Spica_0785 IPR014100 GTP-binding protein Obg/CgtA Spica_0785 IPR035101 GTP-binding protein, Obg-type Spica_0785 IPR031167 OBG-type guanine nucleotide-binding (G) domain Spica_0785 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0785 IPR006073 GTP binding domain Spica_0785 IPR036726 GTP1/OBG domain superfamily Spica_0785 IPR006169 GTP1/OBG domain Spica_0785 IPR006074 GTP1/OBG, conserved site Spica_0786 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0786 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase Spica_0786 IPR004821 Cytidyltransferase-like domain Spica_0788 IPR004394 Protein Iojap/ribosomal silencing factor RsfS Spica_0790 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_0790 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0790 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Spica_0790 IPR006204 GHMP kinase N-terminal domain Spica_0790 IPR036554 GHMP kinase, C-terminal domain superfamily Spica_0790 IPR013750 GHMP kinase, C-terminal domain Spica_0791 IPR007170 Stage V sporulation protein G Spica_0791 IPR036751 Stage V sporulation protein G superfamily Spica_0792 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Spica_0792 IPR001021 Ribosomal protein L25, long-form Spica_0792 IPR020057 Ribosomal protein L25, beta domain Spica_0792 IPR037121 Ribosomal protein L25, C-terminal Spica_0792 IPR029751 Ribosomal protein L25 Spica_0792 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily Spica_0793 IPR012094 tRNA(Ile)-lysidine synthase Spica_0793 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Spica_0793 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0793 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal Spica_0793 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal Spica_0794 IPR000642 Peptidase M41 Spica_0794 IPR003593 AAA+ ATPase domain Spica_0794 IPR041569 AAA ATPase, AAA+ lid domain Spica_0794 IPR003959 ATPase, AAA-type, core Spica_0794 IPR003960 ATPase, AAA-type, conserved site Spica_0794 IPR005936 Peptidase, FtsH Spica_0794 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0794 IPR037219 Peptidase M41-like Spica_0794 IPR011546 Peptidase M41, FtsH extracellular Spica_0796 IPR001940 Peptidase S1C Spica_0796 IPR009003 Peptidase S1, PA clan Spica_0796 IPR036034 PDZ superfamily Spica_0796 IPR001478 PDZ domain Spica_0798 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0798 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily Spica_0798 IPR004105 Histidine kinase CheA-like, homodimeric domain Spica_0798 IPR036061 CheW-like domain superfamily Spica_0798 IPR002545 CheW-like domain Spica_0798 IPR035891 CheY-binding domain of CheA Spica_0798 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_0798 IPR036641 HPT domain superfamily Spica_0798 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_0798 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily Spica_0798 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain Spica_0798 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding Spica_0798 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0798 IPR005467 Histidine kinase domain Spica_0799 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily Spica_0799 IPR000780 MCP methyltransferase, CheR-type Spica_0799 IPR026024 Chemotaxis protein methyltransferase CheR Spica_0799 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal Spica_0799 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_0799 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal Spica_0800 IPR001789 Signal transduction response regulator, receiver domain Spica_0800 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase Spica_0800 IPR035909 Methylesterase CheB, C-terminal Spica_0800 IPR008248 Protein-glutamate methylesterase/protein-glutamine glutaminase, CheB type Spica_0800 IPR011006 CheY-like superfamily Spica_0801 IPR011006 CheY-like superfamily Spica_0801 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0801 IPR039420 Transcriptional regulatory protein WalR-like Spica_0801 IPR001789 Signal transduction response regulator, receiver domain Spica_0801 IPR011879 Signal transduction response regulator, phosphate regulon transcriptional regulatory protein PhoB Spica_0801 IPR001867 OmpR/PhoB-type DNA-binding domain Spica_0802 IPR036061 CheW-like domain superfamily Spica_0802 IPR002545 CheW-like domain Spica_0802 IPR039315 Chemotaxis protein CheW Spica_0803 IPR013656 PAS fold-4 Spica_0803 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_0803 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0803 IPR005467 Histidine kinase domain Spica_0803 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_0803 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_0803 IPR000014 PAS domain Spica_0803 IPR035965 PAS domain superfamily Spica_0803 IPR001789 Signal transduction response regulator, receiver domain Spica_0803 IPR011006 CheY-like superfamily Spica_0803 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0806 IPR005225 Small GTP-binding protein domain Spica_0806 IPR000640 Elongation factor EFG, domain V-like Spica_0806 IPR006297 Elongation factor 4 Spica_0806 IPR041095 Elongation Factor G, domain II Spica_0806 IPR035647 EF-G domain III/V-like Spica_0806 IPR004161 Translation elongation factor EFTu-like, domain 2 Spica_0806 IPR038363 LepA, C-terminal domain superfamily Spica_0806 IPR009000 Translation protein, beta-barrel domain superfamily Spica_0806 IPR000795 Transcription factor, GTP-binding domain Spica_0806 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0806 IPR035654 Elongation factor 4, domain IV Spica_0806 IPR013842 GTP-binding protein LepA, C-terminal Spica_0807 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like Spica_0808 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type Spica_0808 IPR023034 Peptidyl-prolyl isomerase SurA Spica_0808 IPR015391 SurA N-terminal Spica_0808 IPR027304 Trigger factor/SurA domain superfamily Spica_0809 IPR015943 WD40/YVTN repeat-like-containing domain superfamily Spica_0809 IPR011045 Nitrous oxide reductase, N-terminal Spica_0809 IPR019405 Lactonase, 7-bladed beta propeller Spica_0811 IPR023210 NADP-dependent oxidoreductase domain Spica_0811 IPR036812 NADP-dependent oxidoreductase domain superfamily Spica_0814 IPR028082 Periplasmic binding protein-like I Spica_0814 IPR010982 Lambda repressor-like, DNA-binding domain superfamily Spica_0814 IPR000843 LacI-type HTH domain Spica_0815 IPR023064 D-ribose pyranase Spica_0815 IPR023750 RbsD-like superfamily Spica_0815 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU Spica_0816 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0816 IPR003593 AAA+ ATPase domain Spica_0816 IPR003439 ABC transporter-like Spica_0816 IPR017871 ABC transporter, conserved site Spica_0816 IPR015861 ABC transporter, ribose import, RbsA Spica_0817 IPR001851 ABC transporter, permease Spica_0818 IPR025997 Periplasmic binding protein Spica_0818 IPR028082 Periplasmic binding protein-like I Spica_0824 IPR000757 Glycoside hydrolase family 16 Spica_0824 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Spica_0824 IPR008263 Glycoside hydrolase, family 16, active site Spica_0828 IPR035906 MetI-like superfamily Spica_0828 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0829 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_0829 IPR035906 MetI-like superfamily Spica_0830 IPR000843 LacI-type HTH domain Spica_0830 IPR010982 Lambda repressor-like, DNA-binding domain superfamily Spica_0830 IPR028082 Periplasmic binding protein-like I Spica_0830 IPR023588 Transcription regulator HTH, PurR Spica_0831 IPR012341 Six-hairpin glycosidase-like superfamily Spica_0831 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase Spica_0831 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily Spica_0831 IPR005196 Glycoside hydrolase, family 65, N-terminal Spica_0831 IPR005195 Glycoside hydrolase, family 65, central catalytic Spica_0831 IPR005194 Glycoside hydrolase family 65, C-terminal Spica_0831 IPR011013 Galactose mutarotase-like domain superfamily Spica_0831 IPR008928 Six-hairpin glycosidase superfamily Spica_0832 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_0832 IPR022066 Signal transduction histidine kinase, N-terminal Spica_0832 IPR038424 Signal transduction histidine kinase, N-terminal domain superfamily Spica_0832 IPR035965 PAS domain superfamily Spica_0832 IPR005467 Histidine kinase domain Spica_0832 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0832 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0833 IPR036944 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal domain superfamily Spica_0833 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain Spica_0833 IPR000774 Peptidyl-prolyl cis-trans isomerase, FKBP-type, N-terminal Spica_0834 IPR036850 Nucleoside diphosphate kinase-like domain superfamily Spica_0834 IPR034907 Nucleoside diphosphate kinase-like domain Spica_0834 IPR001564 Nucleoside diphosphate kinase Spica_0835 IPR028082 Periplasmic binding protein-like I Spica_0835 IPR028081 Leucine-binding protein domain Spica_0836 IPR001851 ABC transporter, permease Spica_0837 IPR001851 ABC transporter, permease Spica_0837 IPR021807 High-affinity branched-chain amino acid transport system permease, LivHM, N-terminal Spica_0838 IPR003593 AAA+ ATPase domain Spica_0838 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0838 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Spica_0838 IPR017871 ABC transporter, conserved site Spica_0838 IPR003439 ABC transporter-like Spica_0839 IPR017871 ABC transporter, conserved site Spica_0839 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0839 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein Spica_0839 IPR003593 AAA+ ATPase domain Spica_0839 IPR003439 ABC transporter-like Spica_0840 IPR015590 Aldehyde dehydrogenase domain Spica_0840 IPR016162 Aldehyde dehydrogenase, N-terminal Spica_0840 IPR016163 Aldehyde dehydrogenase, C-terminal Spica_0840 IPR016161 Aldehyde/histidinol dehydrogenase Spica_0840 IPR012134 Glutamate-5-semialdehyde dehydrogenase Spica_0840 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site Spica_0840 IPR000965 GPR domain Spica_0841 IPR041739 Glutamate-5-kinase domain Spica_0841 IPR001057 Glutamate/acetylglutamate kinase Spica_0841 IPR011529 Glutamate 5-kinase Spica_0841 IPR001048 Aspartate/glutamate/uridylate kinase Spica_0841 IPR019797 Glutamate 5-kinase, conserved site Spica_0841 IPR036393 Acetylglutamate kinase-like superfamily Spica_0841 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase Spica_0842 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily Spica_0842 IPR000304 Pyrroline-5-carboxylate reductase Spica_0842 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain Spica_0842 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal Spica_0842 IPR036291 NAD(P)-binding domain superfamily Spica_0844 IPR002772 Glycoside hydrolase family 3 C-terminal domain Spica_0844 IPR019800 Glycoside hydrolase, family 3, active site Spica_0844 IPR017853 Glycoside hydrolase superfamily Spica_0844 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily Spica_0844 IPR001764 Glycoside hydrolase, family 3, N-terminal Spica_0844 IPR036881 Glycoside hydrolase family 3 C-terminal domain superfamily Spica_0845 IPR005982 Thioredoxin reductase Spica_0845 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site Spica_0845 IPR023753 FAD/NAD(P)-binding domain Spica_0845 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_0846 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_0846 IPR033479 Double Cache domain 1 Spica_0846 IPR029151 Periplasmic sensor-like domain superfamily Spica_0846 IPR003660 HAMP domain Spica_0846 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding Spica_0849 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0849 IPR042189 Sigma-70 factor, region 1.1 superfamily Spica_0849 IPR028630 RNA polymerase sigma factor RpoD Spica_0849 IPR007624 RNA polymerase sigma-70 region 3 Spica_0849 IPR007627 RNA polymerase sigma-70 region 2 Spica_0849 IPR012760 RNA polymerase sigma factor RpoD, C-terminal Spica_0849 IPR007127 RNA polymerase sigma factor 70, region 1.1 Spica_0849 IPR007630 RNA polymerase sigma-70 region 4 Spica_0849 IPR014284 RNA polymerase sigma-70 like domain Spica_0849 IPR000943 RNA polymerase sigma-70 Spica_0849 IPR009042 RNA polymerase sigma-70 region 1.2 Spica_0849 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_0849 IPR013325 RNA polymerase sigma factor, region 2 Spica_0851 IPR000905 Gcp-like domain Spica_0851 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD Spica_0851 IPR017861 Kae1/TsaD family Spica_0853 IPR000640 Elongation factor EFG, domain V-like Spica_0853 IPR004161 Translation elongation factor EFTu-like, domain 2 Spica_0853 IPR031157 Tr-type G domain, conserved site Spica_0853 IPR005517 Translation elongation factor EFG/EF2, domain IV Spica_0853 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_0853 IPR004540 Translation elongation factor EFG/EF2 Spica_0853 IPR009000 Translation protein, beta-barrel domain superfamily Spica_0853 IPR000795 Transcription factor, GTP-binding domain Spica_0853 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0853 IPR035647 EF-G domain III/V-like Spica_0853 IPR005225 Small GTP-binding protein domain Spica_0853 IPR035649 EFG, domain V Spica_0853 IPR041095 Elongation Factor G, domain II Spica_0853 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_0853 IPR009022 Elongation factor G, domain III Spica_0854 IPR004437 ParB/RepB/Spo0J partition protein Spica_0854 IPR036086 ParB/Sulfiredoxin superfamily Spica_0854 IPR003115 ParB/Sulfiredoxin Spica_0854 IPR041468 ParB/Spo0J, HTH domain Spica_0855 IPR001460 Penicillin-binding protein, transpeptidase Spica_0855 IPR031376 Penicillin-binding protein, OB-like domain Spica_0855 IPR001264 Glycosyl transferase, family 51 Spica_0855 IPR036950 Penicillin binding protein transglycosylase domain Spica_0855 IPR012338 Beta-lactamase/transpeptidase-like Spica_0855 IPR023346 Lysozyme-like domain superfamily Spica_0857 IPR000841 Peptidase M23A, B-lytic metalloendopeptidase Spica_0857 IPR011055 Duplicated hybrid motif Spica_0858 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_0858 IPR000813 7Fe ferredoxin Spica_0858 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_0861 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain superfamily Spica_0861 IPR004090 Chemotaxis methyl-accepting receptor Spica_0861 IPR004091 Chemotaxis methyl-accepting receptor, methyl-accepting site Spica_0861 IPR003660 HAMP domain Spica_0861 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_0861 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding Spica_0862 IPR011258 BPG-independent PGAM, N-terminal Spica_0862 IPR017850 Alkaline-phosphatase-like, core domain superfamily Spica_0862 IPR006124 Metalloenzyme Spica_0862 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily Spica_0862 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent Spica_0864 IPR003353 Phosphotransferase system, fructose-specific IIB subunit Spica_0864 IPR002178 PTS EIIA type-2 domain Spica_0864 IPR006327 Phosphotransferase system, fructose IIC component Spica_0864 IPR004715 Phosphotransferase system, IIA component fructose subfamily Spica_0864 IPR013014 Phosphotransferase system, EIIC component, type 2 Spica_0864 IPR003501 Phosphotransferase system, EIIB component, type 2/3 Spica_0864 IPR016152 Phosphotransferase/anion transporter Spica_0864 IPR013011 Phosphotransferase system, EIIB component, type 2 Spica_0864 IPR036095 PTS system IIB component-like superfamily Spica_0874 IPR001173 Glycosyltransferase 2-like Spica_0874 IPR029044 Nucleotide-diphospho-sugar transferases Spica_0875 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily Spica_0875 IPR006275 Carbamoyl-phosphate synthase, large subunit Spica_0875 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain Spica_0875 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain Spica_0875 IPR011607 Methylglyoxal synthase-like domain Spica_0875 IPR036914 Methylglyoxal synthase-like domain superfamily Spica_0875 IPR033937 Carbamoyl-phosphate synthase large chain, methylglyoxal synthase-like domain Spica_0875 IPR016185 Pre-ATP-grasp domain superfamily Spica_0875 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain Spica_0875 IPR011761 ATP-grasp fold Spica_0876 IPR006274 Carbamoyl-phosphate synthase, small subunit Spica_0876 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain Spica_0876 IPR035686 Carbamoyl-phosphate synthase small subunit, GATase1 domain Spica_0876 IPR029062 Class I glutamine amidotransferase-like Spica_0876 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily Spica_0876 IPR017926 Glutamine amidotransferase Spica_0877 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC Spica_0877 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily Spica_0877 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain Spica_0878 IPR002563 Flavin reductase like domain Spica_0878 IPR001279 Metallo-beta-lactamase Spica_0878 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_0878 IPR012349 FMN-binding split barrel Spica_0878 IPR008254 Flavodoxin/nitric oxide synthase Spica_0878 IPR029039 Flavoprotein-like superfamily Spica_0879 IPR005330 MHYT domain Spica_0879 IPR000160 GGDEF domain Spica_0879 IPR035919 EAL domain superfamily Spica_0879 IPR001633 EAL domain Spica_0879 IPR029787 Nucleotide cyclase Spica_0880 IPR001789 Signal transduction response regulator, receiver domain Spica_0880 IPR011006 CheY-like superfamily Spica_0884 IPR016117 ArgJ-like domain superfamily Spica_0884 IPR042195 ArgJ beta chain, C-terminal domain Spica_0884 IPR002813 Arginine biosynthesis protein ArgJ Spica_0885 IPR036393 Acetylglutamate kinase-like superfamily Spica_0885 IPR004662 Acetylglutamate kinase family Spica_0885 IPR037528 Acetylglutamate kinase ArgB Spica_0885 IPR001048 Aspartate/glutamate/uridylate kinase Spica_0885 IPR001057 Glutamate/acetylglutamate kinase Spica_0885 IPR041727 N-Acetyl-L-glutamate kinase, cyclic Spica_0886 IPR015424 Pyridoxal phosphate-dependent transferase Spica_0886 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_0886 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_0886 IPR004636 Acetylornithine/Succinylornithine transaminase family Spica_0886 IPR005814 Aminotransferase class-III Spica_0887 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body Spica_0887 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0887 IPR023434 Argininosuccinate synthase, type 1 subfamily Spica_0887 IPR018223 Argininosuccinate synthase, conserved site Spica_0887 IPR001518 Argininosuccinate synthase Spica_0888 IPR020557 Fumarate lyase, conserved site Spica_0888 IPR024083 Fumarase/histidase, N-terminal Spica_0888 IPR009049 Argininosuccinate lyase Spica_0888 IPR008948 L-Aspartase-like Spica_0888 IPR000362 Fumarate lyase family Spica_0888 IPR022761 Fumarate lyase, N-terminal Spica_0888 IPR029419 Argininosuccinate lyase, C-terminal Spica_0890 IPR004627 L-threonine 3-dehydrogenase Spica_0890 IPR036291 NAD(P)-binding domain superfamily Spica_0890 IPR020843 Polyketide synthase, enoylreductase domain Spica_0890 IPR013154 Alcohol dehydrogenase, N-terminal Spica_0890 IPR013149 Alcohol dehydrogenase, C-terminal Spica_0890 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site Spica_0890 IPR011032 GroES-like superfamily Spica_0891 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain Spica_0891 IPR033910 Glutamyl-tRNA synthetase Spica_0891 IPR000924 Glutamyl/glutaminyl-tRNA synthetase Spica_0891 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial Spica_0891 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 Spica_0891 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding Spica_0891 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_0893 IPR023696 Ureohydrolase domain superfamily Spica_0893 IPR006035 Ureohydrolase Spica_0893 IPR020855 Ureohydrolase, manganese-binding site Spica_0893 IPR014033 Arginase Spica_0896 IPR027031 Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 Spica_0896 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) Spica_0896 IPR006195 Aminoacyl-tRNA synthetase, class II Spica_0896 IPR004154 Anticodon-binding Spica_0896 IPR036621 Anticodon-binding domain superfamily Spica_0896 IPR002315 Glycyl-tRNA synthetase Spica_0896 IPR033731 Glycyl-tRNA synthetase-like core domain Spica_0896 IPR022961 Glycine-tRNA ligase, bacterial Spica_0899 IPR011607 Methylglyoxal synthase-like domain Spica_0899 IPR011761 ATP-grasp fold Spica_0899 IPR006275 Carbamoyl-phosphate synthase, large subunit Spica_0899 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily Spica_0899 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain Spica_0899 IPR016185 Pre-ATP-grasp domain superfamily Spica_0899 IPR033937 Carbamoyl-phosphate synthase large chain, methylglyoxal synthase-like domain Spica_0899 IPR036914 Methylglyoxal synthase-like domain superfamily Spica_0899 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain Spica_0899 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain Spica_0909 IPR010982 Lambda repressor-like, DNA-binding domain superfamily Spica_0909 IPR001387 Cro/C1-type helix-turn-helix domain Spica_0914 IPR022742 Serine aminopeptidase, S33 Spica_0914 IPR012354 Esterase/lipase Spica_0914 IPR029058 Alpha/Beta hydrolase fold Spica_0917 IPR013785 Aldolase-type TIM barrel Spica_0917 IPR011343 Deoxyribose-phosphate aldolase Spica_0917 IPR002915 DeoC/FbaB/ lacD aldolase Spica_0917 IPR028581 Deoxyribose-phosphate aldolase type I Spica_0918 IPR028082 Periplasmic binding protein-like I Spica_0918 IPR003760 ABC transporter substrate-binding protein PnrA-like Spica_0922 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily Spica_0922 IPR002318 Alanine-tRNA ligase, class IIc Spica_0922 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria Spica_0922 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal Spica_0922 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily Spica_0922 IPR012947 Threonyl/alanyl tRNA synthetase, SAD Spica_0922 IPR018165 Alanyl-tRNA synthetase, class IIc, core domain Spica_0923 IPR027304 Trigger factor/SurA domain superfamily Spica_0923 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Spica_0923 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type Spica_0923 IPR023059 Foldase protein PrsA Spica_0924 IPR011605 NusB antitermination factor Spica_0924 IPR006027 NusB/RsmB/TIM44 Spica_0924 IPR035926 NusB-like superfamily Spica_0926 IPR020818 GroES chaperonin family Spica_0926 IPR037124 GroES chaperonin superfamily Spica_0926 IPR018369 Chaperonin GroES, conserved site Spica_0926 IPR011032 GroES-like superfamily Spica_0928 IPR007630 RNA polymerase sigma-70 region 4 Spica_0928 IPR007627 RNA polymerase sigma-70 region 2 Spica_0928 IPR009042 RNA polymerase sigma-70 region 1.2 Spica_0928 IPR007624 RNA polymerase sigma-70 region 3 Spica_0928 IPR028630 RNA polymerase sigma factor RpoD Spica_0928 IPR042189 Sigma-70 factor, region 1.1 superfamily Spica_0928 IPR013325 RNA polymerase sigma factor, region 2 Spica_0928 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_0928 IPR000943 RNA polymerase sigma-70 Spica_0928 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0928 IPR007127 RNA polymerase sigma factor 70, region 1.1 Spica_0928 IPR014284 RNA polymerase sigma-70 like domain Spica_0928 IPR012760 RNA polymerase sigma factor RpoD, C-terminal Spica_0929 IPR006195 Aminoacyl-tRNA synthetase, class II Spica_0929 IPR004618 Aspartate--ammonia ligase Spica_0930 IPR000524 Transcription regulator HTH, GntR Spica_0930 IPR015424 Pyridoxal phosphate-dependent transferase Spica_0930 IPR004839 Aminotransferase, class I/classII Spica_0930 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_0930 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0930 IPR036390 Winged helix DNA-binding domain superfamily Spica_0930 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_0931 IPR033755 PdxS/SNZ N-terminal domain Spica_0931 IPR011060 Ribulose-phosphate binding barrel Spica_0931 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ Spica_0931 IPR013785 Aldolase-type TIM barrel Spica_0934 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase Spica_0934 IPR033524 Leu/Phe/Val dehydrogenases active site Spica_0934 IPR014362 Glutamate dehydrogenase Spica_0934 IPR036291 NAD(P)-binding domain superfamily Spica_0934 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal Spica_0934 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain Spica_0934 IPR033922 NAD(P) binding domain of glutamate dehydrogenase Spica_0937 IPR013766 Thioredoxin domain Spica_0937 IPR036249 Thioredoxin-like superfamily Spica_0938 IPR010982 Lambda repressor-like, DNA-binding domain superfamily Spica_0938 IPR001387 Cro/C1-type helix-turn-helix domain Spica_0939 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit Spica_0939 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 Spica_0939 IPR033941 3-Isopropylmalate dehydratase, catalytic domain Spica_0939 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain Spica_0939 IPR018136 Aconitase family, 4Fe-4S cluster binding site Spica_0939 IPR036008 Aconitase, iron-sulfur domain Spica_0939 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic Spica_0940 IPR011824 Hydrolyase LeuD/DmdB, bacterial Spica_0940 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel Spica_0940 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain Spica_0940 IPR011827 Hydrolyase LeuD/HacB/DmdB Spica_0940 IPR033940 3-isopropylmalate dehydratase, swivel domain Spica_0941 IPR024989 Major facilitator superfamily associated domain Spica_0941 IPR026032 Probable 3-phenylpropionic acid transporter Spica_0941 IPR036259 MFS transporter superfamily Spica_0941 IPR020846 Major facilitator superfamily domain Spica_0942 IPR007563 Protein of unknown function DUF554 Spica_0943 IPR040582 MalK, OB fold domain Spica_0943 IPR017871 ABC transporter, conserved site Spica_0943 IPR003439 ABC transporter-like Spica_0943 IPR003593 AAA+ ATPase domain Spica_0943 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0943 IPR005116 Transport-associated OB, type 1 Spica_0943 IPR008995 Molybdate/tungstate binding, C-terminal Spica_0944 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_0945 IPR005659 Chemoreceptor glutamine deamidase CheD Spica_0945 IPR011324 Cytotoxic necrotizing factor-like, catalytic Spica_0945 IPR038592 CheD-like superfamily Spica_0946 IPR001900 Ribonuclease II/R Spica_0946 IPR012340 Nucleic acid-binding, OB-fold Spica_0947 IPR001048 Aspartate/glutamate/uridylate kinase Spica_0947 IPR018042 Aspartate kinase, conserved site Spica_0947 IPR041745 Lysine-sensitive aspartokinase 3, N-terminal catalytic domain Spica_0947 IPR001341 Aspartate kinase Spica_0947 IPR036393 Acetylglutamate kinase-like superfamily Spica_0947 IPR005260 Aspartate kinase, monofunctional class Spica_0947 IPR002912 ACT domain Spica_0948 IPR036291 NAD(P)-binding domain superfamily Spica_0948 IPR023940 Dihydrodipicolinate reductase Spica_0948 IPR022663 Dihydrodipicolinate reductase, C-terminal Spica_0948 IPR000846 Dihydrodipicolinate reductase, N-terminal Spica_0949 IPR020624 Schiff base-forming aldolase, conserved site Spica_0949 IPR002220 DapA-like Spica_0949 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA Spica_0949 IPR013785 Aldolase-type TIM barrel Spica_0950 IPR012080 Aspartate-semialdehyde dehydrogenase Spica_0950 IPR005676 Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking Spica_0950 IPR036291 NAD(P)-binding domain superfamily Spica_0950 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site Spica_0950 IPR000534 Semialdehyde dehydrogenase, NAD-binding Spica_0950 IPR012280 Semialdehyde dehydrogenase, dimerisation domain Spica_0951 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal Spica_0951 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Spica_0951 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal Spica_0951 IPR000183 Ornithine/DAP/Arg decarboxylase Spica_0951 IPR029066 PLP-binding barrel Spica_0951 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Spica_0951 IPR002986 Diaminopimelate decarboxylase, LysA Spica_0951 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal Spica_0952 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_0952 IPR004839 Aminotransferase, class I/classII Spica_0952 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_0952 IPR015424 Pyridoxal phosphate-dependent transferase Spica_0952 IPR019942 LL-diaminopimelate aminotransferase/aminotransferase ALD1 Spica_0954 IPR001584 Integrase, catalytic core Spica_0954 IPR025948 HTH-like domain Spica_0954 IPR036397 Ribonuclease H superfamily Spica_0954 IPR012337 Ribonuclease H-like superfamily Spica_0958 IPR035891 CheY-binding domain of CheA Spica_0958 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0958 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0958 IPR005467 Histidine kinase domain Spica_0958 IPR004105 Histidine kinase CheA-like, homodimeric domain Spica_0958 IPR002545 CheW-like domain Spica_0958 IPR036061 CheW-like domain superfamily Spica_0958 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding Spica_0958 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain Spica_0958 IPR036641 HPT domain superfamily Spica_0958 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_0959 IPR002545 CheW-like domain Spica_0959 IPR036061 CheW-like domain superfamily Spica_0959 IPR039315 Chemotaxis protein CheW Spica_0961 IPR001789 Signal transduction response regulator, receiver domain Spica_0961 IPR011006 CheY-like superfamily Spica_0962 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding Spica_0962 IPR036291 NAD(P)-binding domain superfamily Spica_0962 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal Spica_0962 IPR019796 Glucose-6-phosphate dehydrogenase, active site Spica_0962 IPR001282 Glucose-6-phosphate dehydrogenase Spica_0964 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Spica_0964 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Spica_0964 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 Spica_0964 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain Spica_0964 IPR036291 NAD(P)-binding domain superfamily Spica_0966 IPR013185 Translation elongation factor, KOW-like Spica_0966 IPR008991 Translation protein SH3-like domain superfamily Spica_0966 IPR015365 Elongation factor P, C-terminal Spica_0966 IPR012340 Nucleic acid-binding, OB-fold Spica_0966 IPR011768 Translation elongation factor P Spica_0966 IPR001059 Translation elongation factor P/YeiP, central Spica_0966 IPR014722 Ribosomal protein L2, domain 2 Spica_0966 IPR020599 Translation elongation factor P/YeiP Spica_0967 IPR017055 Signal transduction histidine kinase, DctB (C4-dicarboxylate transport system regulator) Spica_0967 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_0967 IPR029151 Periplasmic sensor-like domain superfamily Spica_0967 IPR003594 Histidine kinase/HSP90-like ATPase Spica_0967 IPR033479 Double Cache domain 1 Spica_0967 IPR005467 Histidine kinase domain Spica_0967 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_0967 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_0967 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_0968 IPR003593 AAA+ ATPase domain Spica_0968 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0968 IPR002197 DNA binding HTH domain, Fis-type Spica_0968 IPR009057 Homeobox-like domain superfamily Spica_0968 IPR001789 Signal transduction response regulator, receiver domain Spica_0968 IPR011006 CheY-like superfamily Spica_0968 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_0968 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_0968 IPR025944 Sigma-54 interaction domain, conserved site Spica_0968 IPR002078 RNA polymerase sigma factor 54 interaction domain Spica_0969 IPR036868 TusA-like domain superfamily Spica_0969 IPR001455 TusA-like domain Spica_0970 IPR007272 Sulphur transport domain Spica_0971 IPR007272 Sulphur transport domain Spica_0972 IPR005982 Thioredoxin reductase Spica_0972 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site Spica_0972 IPR023753 FAD/NAD(P)-binding domain Spica_0972 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_0973 IPR019591 Mrp/NBP35 ATP-binding protein Spica_0973 IPR000808 Mrp, conserved site Spica_0973 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 Spica_0973 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_0975 IPR001360 Glycoside hydrolase family 1 Spica_0975 IPR018120 Glycoside hydrolase family 1, active site Spica_0975 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase Spica_0975 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site Spica_0975 IPR017853 Glycoside hydrolase superfamily Spica_0976 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_0976 IPR000600 ROK family Spica_0976 IPR036390 Winged helix DNA-binding domain superfamily Spica_0977 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) Spica_0977 IPR004525 Elongation factor P--(R)-beta-lysine ligase Spica_0977 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal Spica_0977 IPR006195 Aminoacyl-tRNA synthetase, class II Spica_0978 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase Spica_0978 IPR036565 Mur-like, catalytic domain superfamily Spica_0978 IPR004101 Mur ligase, C-terminal Spica_0978 IPR036615 Mur ligase, C-terminal domain superfamily Spica_0978 IPR013221 Mur ligase, central Spica_0983 IPR013815 ATP-grasp fold, subdomain 1 Spica_0983 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site Spica_0983 IPR005905 D-alanine--D-alanine ligase Spica_0983 IPR011095 D-alanine--D-alanine ligase, C-terminal Spica_0983 IPR011127 D-alanine--D-alanine ligase, N-terminal domain Spica_0983 IPR016185 Pre-ATP-grasp domain superfamily Spica_0983 IPR011761 ATP-grasp fold Spica_0984 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase Spica_0984 IPR035911 MurE/MurF, N-terminal Spica_0984 IPR000713 Mur ligase, N-terminal catalytic domain Spica_0984 IPR013221 Mur ligase, central Spica_0984 IPR036615 Mur ligase, C-terminal domain superfamily Spica_0984 IPR004101 Mur ligase, C-terminal Spica_0984 IPR036565 Mur-like, catalytic domain superfamily Spica_0986 IPR023472 Uncharacterised protein family MJ0810 Spica_0986 IPR027623 AmmeMemoRadiSam system protein A Spica_0986 IPR027485 AMMECR1, N-terminal Spica_0986 IPR002733 AMMECR1 domain Spica_0986 IPR023473 AMMECR1 Spica_0986 IPR036071 AMMECR1 domain superfamily Spica_0988 IPR020556 Amidase, conserved site Spica_0988 IPR036928 Amidase signature (AS) superfamily Spica_0988 IPR023631 Amidase signature domain Spica_0988 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit Spica_0988 IPR000120 Amidase Spica_0989 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain Spica_0989 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site Spica_0989 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 Spica_0989 IPR042114 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 1 Spica_0989 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit Spica_0989 IPR018027 Asn/Gln amidotransferase Spica_0989 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic Spica_0989 IPR017959 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E Spica_0989 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like Spica_0990 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) Spica_0990 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type Spica_0990 IPR012340 Nucleic acid-binding, OB-fold Spica_0990 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb Spica_0990 IPR004523 Aspartate-tRNA synthetase, type 2 Spica_0990 IPR006195 Aminoacyl-tRNA synthetase, class II Spica_0993 IPR012827 Haemerythrin, metal-binding domain Spica_0993 IPR023504 Bacteriohemerythrin-like protein Spica_0993 IPR035938 Hemerythrin-like superfamily Spica_0993 IPR016131 Haemerythrin, iron-binding site Spica_0993 IPR012312 Haemerythrin-like Spica_1000 IPR029787 Nucleotide cyclase Spica_1000 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase Spica_1009 IPR039069 Carbohydrate esterase 7 family Spica_1009 IPR008391 Acetyl xylan esterase Spica_1009 IPR029058 Alpha/Beta hydrolase fold Spica_1013 IPR038071 UROD/MetE-like superfamily Spica_1013 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal Spica_1013 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal Spica_1013 IPR006276 Cobalamin-independent methionine synthase Spica_1014 IPR001764 Glycoside hydrolase, family 3, N-terminal Spica_1014 IPR036962 Glycoside hydrolase, family 3, N-terminal domain superfamily Spica_1014 IPR017853 Glycoside hydrolase superfamily Spica_1014 IPR022956 Beta-hexosaminidase, bacterial Spica_1014 IPR019800 Glycoside hydrolase, family 3, active site Spica_1015 IPR036986 RNA-binding S4 domain superfamily Spica_1015 IPR002942 RNA-binding S4 domain Spica_1015 IPR006225 Pseudouridine synthase, RluC/RluD Spica_1015 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site Spica_1015 IPR006145 Pseudouridine synthase, RsuA/RluA Spica_1015 IPR020103 Pseudouridine synthase, catalytic domain superfamily Spica_1018 IPR016867 Glycine cleavage system transcriptional repressor Spica_1018 IPR002912 ACT domain Spica_1019 IPR004090 Chemotaxis methyl-accepting receptor Spica_1019 IPR000014 PAS domain Spica_1019 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_1019 IPR001610 PAC motif Spica_1019 IPR000700 PAS-associated, C-terminal Spica_1019 IPR035965 PAS domain superfamily Spica_1019 IPR003660 HAMP domain Spica_1021 IPR017583 Tagatose/fructose phosphokinase Spica_1021 IPR029056 Ribokinase-like Spica_1021 IPR011611 Carbohydrate kinase PfkB Spica_1021 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site Spica_1021 IPR005926 Tagatose-6-phosphate kinase Spica_1022 IPR002528 Multi antimicrobial extrusion protein Spica_1026 IPR016047 Peptidase M23 Spica_1026 IPR036779 LysM domain superfamily Spica_1026 IPR011055 Duplicated hybrid motif Spica_1026 IPR018392 LysM domain Spica_1027 IPR009042 RNA polymerase sigma-70 region 1.2 Spica_1027 IPR028630 RNA polymerase sigma factor RpoD Spica_1027 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1027 IPR013325 RNA polymerase sigma factor, region 2 Spica_1027 IPR042189 Sigma-70 factor, region 1.1 superfamily Spica_1027 IPR007627 RNA polymerase sigma-70 region 2 Spica_1027 IPR000943 RNA polymerase sigma-70 Spica_1027 IPR014284 RNA polymerase sigma-70 like domain Spica_1027 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_1027 IPR007127 RNA polymerase sigma factor 70, region 1.1 Spica_1027 IPR007630 RNA polymerase sigma-70 region 4 Spica_1027 IPR007624 RNA polymerase sigma-70 region 3 Spica_1027 IPR012760 RNA polymerase sigma factor RpoD, C-terminal Spica_1028 IPR012337 Ribonuclease H-like superfamily Spica_1028 IPR013520 Exonuclease, RNase T/DNA polymerase III Spica_1028 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain Spica_1028 IPR036397 Ribonuclease H superfamily Spica_1029 IPR005841 Alpha-D-phosphohexomutase superfamily Spica_1029 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III Spica_1029 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II Spica_1029 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III Spica_1029 IPR005843 Alpha-D-phosphohexomutase, C-terminal Spica_1029 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily Spica_1029 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I Spica_1029 IPR016066 Alpha-D-phosphohexomutase, conserved site Spica_1030 IPR005899 Sodium ion-translocating decarboxylase Spica_1031 IPR011053 Single hybrid motif Spica_1031 IPR005776 Oxaloacetate decarboxylase, alpha subunit Spica_1031 IPR003379 Carboxylase, conserved domain Spica_1031 IPR000089 Biotin/lipoyl attachment Spica_1031 IPR001882 Biotin-binding site Spica_1031 IPR013785 Aldolase-type TIM barrel Spica_1031 IPR000891 Pyruvate carboxyltransferase Spica_1032 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Spica_1033 IPR029057 Phosphoribosyltransferase-like Spica_1033 IPR000836 Phosphoribosyltransferase domain Spica_1033 IPR023050 Bifunctional protein PyrR Spica_1037 IPR022898 Ribonuclease HII Spica_1037 IPR001352 Ribonuclease HII/HIII Spica_1037 IPR024567 Ribonuclease HII/HIII domain Spica_1037 IPR012337 Ribonuclease H-like superfamily Spica_1037 IPR036397 Ribonuclease H superfamily Spica_1039 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III Spica_1039 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I Spica_1039 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II Spica_1039 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily Spica_1039 IPR005843 Alpha-D-phosphohexomutase, C-terminal Spica_1039 IPR016066 Alpha-D-phosphohexomutase, conserved site Spica_1039 IPR005841 Alpha-D-phosphohexomutase superfamily Spica_1039 IPR006352 Phosphoglucosamine mutase, bacterial type Spica_1039 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III Spica_1040 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1040 IPR004506 tRNA-specific 2-thiouridylase Spica_1040 IPR023382 Adenine nucleotide alpha hydrolase-like domains Spica_1044 IPR016193 Cytidine deaminase-like Spica_1044 IPR006262 Cytidine deaminase, homotetrameric Spica_1044 IPR002125 Cytidine and deoxycytidylate deaminase domain Spica_1044 IPR016192 APOBEC/CMP deaminase, zinc-binding Spica_1045 IPR016152 Phosphotransferase/anion transporter Spica_1045 IPR006320 Phosphotransferase system, IIA-like nitrogen-regulatory protein PtsN Spica_1045 IPR002178 PTS EIIA type-2 domain Spica_1048 IPR002942 RNA-binding S4 domain Spica_1048 IPR006145 Pseudouridine synthase, RsuA/RluA Spica_1048 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site Spica_1048 IPR020103 Pseudouridine synthase, catalytic domain superfamily Spica_1048 IPR036986 RNA-binding S4 domain superfamily Spica_1049 IPR032585 Protein of unknown function DUF4912 Spica_1050 IPR028995 Glycoside hydrolase families 57/38, central domain superfamily Spica_1050 IPR004300 Glycoside hydrolase family 57, N-terminal domain Spica_1050 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel Spica_1050 IPR015293 Domain of unknown function DUF1957 Spica_1050 IPR040042 1,4-alpha-glucan branching enzyme MT3115-like Spica_1050 IPR037090 Glycoside hydrolase families 57, central domain Spica_1050 IPR027291 Glycoside hydrolase 38, N-terminal domain superfamily Spica_1053 IPR003660 HAMP domain Spica_1053 IPR001932 PPM-type phosphatase domain Spica_1053 IPR036457 PPM-type phosphatase domain superfamily Spica_1056 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_1056 IPR035906 MetI-like superfamily Spica_1057 IPR035906 MetI-like superfamily Spica_1057 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_1065 IPR001036 Acriflavin resistance protein Spica_1065 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 Spica_1065 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_1066 IPR004764 Hydrophobe/amphiphile efflux-1 HAE1 Spica_1066 IPR001036 Acriflavin resistance protein Spica_1066 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_1083 IPR001207 Transposase, mutator type Spica_1086 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1086 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Spica_1086 IPR012089 tRNA-cytidine(32) 2-sulfurtransferase Spica_1086 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type Spica_1088 IPR003607 HD/PDEase domain Spica_1088 IPR006674 HD domain Spica_1089 IPR033941 3-Isopropylmalate dehydratase, catalytic domain Spica_1089 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 Spica_1089 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain Spica_1089 IPR036008 Aconitase, iron-sulfur domain Spica_1089 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic Spica_1089 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit Spica_1093 IPR003658 Anti-sigma factor antagonist Spica_1093 IPR036513 STAS domain superfamily Spica_1093 IPR002645 STAS domain Spica_1095 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1095 IPR003593 AAA+ ATPase domain Spica_1095 IPR032781 ABC-transporter extension domain Spica_1095 IPR003439 ABC transporter-like Spica_1095 IPR017871 ABC transporter, conserved site Spica_1095 IPR022374 Energy-dependent translational throttle protein EttA Spica_1096 IPR005744 Hly-III Spica_1096 IPR004254 AdipoR/Haemolysin-III-related Spica_1097 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1097 IPR007473 Ribosomal RNA large subunit methyltransferase J Spica_1102 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding Spica_1102 IPR002292 Ornithine/putrescine carbamoyltransferase Spica_1102 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain Spica_1102 IPR006130 Aspartate/ornithine carbamoyltransferase Spica_1102 IPR024904 Ornithine carbamoyltransferase Spica_1102 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily Spica_1104 IPR007197 Radical SAM Spica_1104 IPR013785 Aldolase-type TIM barrel Spica_1104 IPR006638 Elp3/MiaB/NifB Spica_1104 IPR013483 Molybdenum cofactor biosynthesis protein A Spica_1104 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site Spica_1104 IPR010505 Molybdenum cofactor synthesis C-terminal Spica_1107 IPR003796 Ribonucleotide reductase regulator NrdR-like Spica_1107 IPR005144 ATP-cone domain Spica_1108 IPR000368 Sucrose synthase Spica_1108 IPR001296 Glycosyl transferase, family 1 Spica_1109 IPR004815 Lon protease, bacterial/eukaryotic-type Spica_1109 IPR027543 Lon protease, bacterial Spica_1109 IPR003959 ATPase, AAA-type, core Spica_1109 IPR003593 AAA+ ATPase domain Spica_1109 IPR008269 Peptidase S16, Lon proteolytic domain Spica_1109 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1109 IPR003111 Lon, substrate-binding domain Spica_1109 IPR008268 Peptidase S16, active site Spica_1109 IPR015947 PUA-like superfamily Spica_1109 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_1109 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_1109 IPR027065 Lon protease Spica_1110 IPR038366 Zinc finger, ClpX C4-type superfamily Spica_1110 IPR003959 ATPase, AAA-type, core Spica_1110 IPR010603 Zinc finger, ClpX C4-type Spica_1110 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1110 IPR019489 Clp ATPase, C-terminal Spica_1110 IPR004487 Clp protease, ATP-binding subunit ClpX Spica_1110 IPR003593 AAA+ ATPase domain Spica_1111 IPR029045 ClpP/crotonase-like domain superfamily Spica_1111 IPR033135 ClpP, histidine active site Spica_1111 IPR001907 ATP-dependent Clp protease proteolytic subunit Spica_1111 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Spica_1112 IPR008881 Trigger factor, ribosome-binding, bacterial Spica_1112 IPR036611 Trigger factor ribosome-binding domain superfamily Spica_1112 IPR037041 Trigger factor, C-terminal domain superfamily Spica_1112 IPR008880 Trigger factor, C-terminal Spica_1112 IPR005215 Trigger factor Spica_1112 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain Spica_1112 IPR027304 Trigger factor/SurA domain superfamily Spica_1115 IPR002371 Flagellar hook-associated protein 1 Spica_1115 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Spica_1115 IPR010810 Flagellin hook, IN motif Spica_1116 IPR001492 Flagellin Spica_1116 IPR001029 Flagellin, D0/D1 domain Spica_1117 IPR003775 Flagellar assembly factor FliW Spica_1117 IPR024046 Flagellar assembly factor FliW domain superfamily Spica_1118 IPR003751 Translational regulator CsrA Spica_1118 IPR036107 Carbon storage regulator superfamily Spica_1119 IPR003660 HAMP domain Spica_1119 IPR003607 HD/PDEase domain Spica_1119 IPR006674 HD domain Spica_1119 IPR037522 HD-GYP domain Spica_1120 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD Spica_1120 IPR017861 Kae1/TsaD family Spica_1120 IPR000905 Gcp-like domain Spica_1121 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1121 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE Spica_1125 IPR003481 Flagellar hook-associated protein 2, N-terminal Spica_1125 IPR040026 Flagellar hook-associated protein 2 Spica_1125 IPR010809 Flagellar hook-associated protein 2, C-terminal Spica_1126 IPR005186 FlaG protein Spica_1126 IPR035924 FlaG-like superfamily Spica_1127 IPR001029 Flagellin, D0/D1 domain Spica_1127 IPR001492 Flagellin Spica_1127 IPR042187 Flagellin, C-terminal domain, subdomain 2 Spica_1128 IPR001029 Flagellin, D0/D1 domain Spica_1128 IPR042187 Flagellin, C-terminal domain, subdomain 2 Spica_1128 IPR001492 Flagellin Spica_1130 IPR021886 MgsA AAA+ ATPase C-terminal Spica_1130 IPR003959 ATPase, AAA-type, core Spica_1130 IPR032423 AAA C-terminal domain Spica_1130 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1130 IPR003593 AAA+ ATPase domain Spica_1130 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal Spica_1133 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site Spica_1133 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Spica_1133 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase Spica_1133 IPR036291 NAD(P)-binding domain superfamily Spica_1133 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Spica_1134 IPR022838 GTP cyclohydrolase FolE2 Spica_1134 IPR003801 GTP cyclohydrolase FolE2/MptA Spica_1136 IPR038135 Methylthiotransferase, N-terminal domain superfamily Spica_1136 IPR006638 Elp3/MiaB/NifB Spica_1136 IPR005839 Methylthiotransferase Spica_1136 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB Spica_1136 IPR020612 Methylthiotransferase, conserved site Spica_1136 IPR007197 Radical SAM Spica_1136 IPR023404 Radical SAM, alpha/beta horseshoe Spica_1136 IPR002792 TRAM domain Spica_1136 IPR013848 Methylthiotransferase, N-terminal Spica_1140 IPR003156 DHHA1 domain Spica_1140 IPR038763 DHH phosphoesterase superfamily Spica_1140 IPR001667 DDH domain Spica_1144 IPR040442 Pyruvate kinase-like domain superfamily Spica_1144 IPR010121 Pyruvate, phosphate dikinase Spica_1144 IPR013815 ATP-grasp fold, subdomain 1 Spica_1144 IPR008279 PEP-utilising enzyme, mobile domain Spica_1144 IPR036637 Phosphohistidine domain superfamily Spica_1144 IPR023151 PEP-utilising enzyme, conserved site Spica_1144 IPR018274 PEP-utilising enzyme, active site Spica_1144 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily Spica_1144 IPR000121 PEP-utilising enzyme, C-terminal Spica_1147 IPR002505 Phosphate acetyl/butaryl transferase Spica_1147 IPR004614 Phosphate acetyltransferase Spica_1147 IPR012147 Phosphate acetyl/butyryltransferase Spica_1147 IPR042112 Phosphate acetyltransferase, domain 2 Spica_1147 IPR042113 Phosphate acetyltransferase, domain 1 Spica_1151 IPR005839 Methylthiotransferase Spica_1151 IPR023404 Radical SAM, alpha/beta horseshoe Spica_1151 IPR007197 Radical SAM Spica_1151 IPR006467 MiaB-like tRNA modifying enzyme Spica_1151 IPR006638 Elp3/MiaB/NifB Spica_1151 IPR020612 Methylthiotransferase, conserved site Spica_1151 IPR038135 Methylthiotransferase, N-terminal domain superfamily Spica_1151 IPR013848 Methylthiotransferase, N-terminal Spica_1154 IPR002589 Macro domain Spica_1155 IPR003746 Protein of unknown function DUF167 Spica_1155 IPR036591 YggU-like superfamily Spica_1159 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_1159 IPR001279 Metallo-beta-lactamase Spica_1162 IPR001920 Asp/Glu racemase Spica_1162 IPR018187 Asp/Glu racemase, active site 1 Spica_1162 IPR004391 Glutamate racemase Spica_1162 IPR015942 Asp/Glu/hydantoin racemase Spica_1163 IPR010914 RsgA GTPase domain Spica_1163 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1163 IPR004881 Ribosome biogenesis GTPase RsgA Spica_1163 IPR012340 Nucleic acid-binding, OB-fold Spica_1163 IPR030378 Circularly permuted (CP)-type guanine nucleotide-binding (G) domain Spica_1163 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal Spica_1164 IPR002625 Smr domain Spica_1164 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1164 IPR005747 Endonuclease MutS2 Spica_1164 IPR036187 DNA mismatch repair protein MutS, core domain superfamily Spica_1164 IPR007696 DNA mismatch repair protein MutS, core Spica_1164 IPR000432 DNA mismatch repair protein MutS, C-terminal Spica_1164 IPR036063 Smr domain superfamily Spica_1167 IPR020900 Arginine repressor, DNA-binding domain Spica_1167 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1167 IPR036251 Arginine repressor, C-terminal domain superfamily Spica_1167 IPR020899 Arginine repressor, C-terminal Spica_1167 IPR001669 Arginine repressor Spica_1167 IPR036390 Winged helix DNA-binding domain superfamily Spica_1168 IPR035476 Phosphoglucose isomerase, SIS domain 1 Spica_1168 IPR018189 Phosphoglucose isomerase, conserved site Spica_1168 IPR035482 Phosphoglucose isomerase, SIS domain 2 Spica_1168 IPR001672 Phosphoglucose isomerase (PGI) Spica_1168 IPR023096 Phosphoglucose isomerase, C-terminal Spica_1169 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_1169 IPR004090 Chemotaxis methyl-accepting receptor Spica_1169 IPR000727 Target SNARE coiled-coil homology domain Spica_1169 IPR033479 Double Cache domain 1 Spica_1169 IPR003660 HAMP domain Spica_1169 IPR029151 Periplasmic sensor-like domain superfamily Spica_1177 IPR002549 Transmembrane protein TqsA-like Spica_1178 IPR022986 Uncharacterised protein family UPF0237, ACT-type Spica_1178 IPR002912 ACT domain Spica_1179 IPR007841 Uncharacterised protein family UPF0210 Spica_1180 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Spica_1180 IPR000445 Helix-hairpin-helix motif Spica_1180 IPR003265 HhH-GPD domain Spica_1180 IPR004035 Endonuclease III, iron-sulphur binding site Spica_1180 IPR004036 Endonuclease III-like, conserved site-2 Spica_1180 IPR011257 DNA glycosylase Spica_1180 IPR005759 Endonuclease III Spica_1180 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif Spica_1181 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain Spica_1181 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1181 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding Spica_1181 IPR033709 Isoleucyl tRNA synthetase type 2, anticodon-binding domain Spica_1181 IPR002301 Isoleucine-tRNA ligase Spica_1181 IPR023586 Isoleucine-tRNA ligase, type 2 Spica_1181 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding Spica_1181 IPR002300 Aminoacyl-tRNA synthetase, class Ia Spica_1188 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily Spica_1188 IPR002569 Peptide methionine sulphoxide reductase MsrA Spica_1189 IPR015376 Zinc ribbon, NADH pyrophosphatase Spica_1189 IPR022925 NADH pyrophosphatase NudC Spica_1189 IPR015797 NUDIX hydrolase-like domain superfamily Spica_1189 IPR020084 NUDIX hydrolase, conserved site Spica_1189 IPR000086 NUDIX hydrolase domain Spica_1189 IPR015375 NADH pyrophosphatase-like, N-terminal Spica_1190 IPR020557 Fumarate lyase, conserved site Spica_1190 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily Spica_1190 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain Spica_1190 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain Spica_1190 IPR011167 Iron-dependent fumarate hydratase Spica_1192 IPR000014 PAS domain Spica_1192 IPR001610 PAC motif Spica_1192 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_1192 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_1192 IPR005467 Histidine kinase domain Spica_1192 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1192 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1192 IPR000700 PAS-associated, C-terminal Spica_1192 IPR013767 PAS fold Spica_1192 IPR035965 PAS domain superfamily Spica_1192 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_1193 IPR025944 Sigma-54 interaction domain, conserved site Spica_1193 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_1193 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_1193 IPR001789 Signal transduction response regulator, receiver domain Spica_1193 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1193 IPR002197 DNA binding HTH domain, Fis-type Spica_1193 IPR002078 RNA polymerase sigma factor 54 interaction domain Spica_1193 IPR011006 CheY-like superfamily Spica_1193 IPR003593 AAA+ ATPase domain Spica_1193 IPR009057 Homeobox-like domain superfamily Spica_1195 IPR001107 Band 7 domain Spica_1195 IPR010200 HflC Spica_1195 IPR036013 Band 7/SPFH domain superfamily Spica_1196 IPR010201 HflK Spica_1196 IPR001107 Band 7 domain Spica_1196 IPR036013 Band 7/SPFH domain superfamily Spica_1197 IPR036161 RPB6/omega subunit-like superfamily Spica_1197 IPR006110 RNA polymerase, subunit omega/K/RPB6 Spica_1198 IPR018022 IPP transferase Spica_1198 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1198 IPR039657 Dimethylallyltransferase Spica_1199 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II Spica_1199 IPR020826 Transketolase binding site Spica_1199 IPR029061 Thiamin diphosphate-binding fold Spica_1199 IPR033248 Transketolase, C-terminal domain Spica_1199 IPR005475 Transketolase-like, pyrimidine-binding domain Spica_1199 IPR005477 Deoxyxylulose-5-phosphate synthase Spica_1199 IPR005474 Transketolase, N-terminal Spica_1200 IPR011005 Dihydropteroate synthase-like Spica_1200 IPR006390 Dihydropteroate synthase Spica_1200 IPR000489 Pterin-binding domain Spica_1201 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily Spica_1201 IPR034701 Diadenylate cyclase CdaA Spica_1201 IPR014046 Diadenylate cyclase Spica_1201 IPR003390 DNA integrity scanning protein, DisA, N-terminal Spica_1202 IPR012505 YbbR-like Spica_1203 IPR004568 Phosphopantetheine-protein transferase domain Spica_1203 IPR002582 Holo-[acyl carrier protein] synthase Spica_1203 IPR037143 4'-phosphopantetheinyl transferase domain superfamily Spica_1203 IPR008278 4'-phosphopantetheinyl transferase domain Spica_1205 IPR001406 Pseudouridine synthase I, TruA Spica_1205 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain Spica_1205 IPR020095 Pseudouridine synthase I, TruA, C-terminal Spica_1205 IPR020103 Pseudouridine synthase, catalytic domain superfamily Spica_1206 IPR023544 ABC transporter, vitamin B12-binding protein Spica_1206 IPR002491 ABC transporter periplasmic binding domain Spica_1207 IPR037294 ABC transporter, BtuC-like Spica_1207 IPR000522 ABC transporter, permease protein, BtuC-like Spica_1208 IPR003439 ABC transporter-like Spica_1208 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1208 IPR017871 ABC transporter, conserved site Spica_1208 IPR003593 AAA+ ATPase domain Spica_1209 IPR001544 Aminotransferase class IV Spica_1209 IPR005784 D-amino acid aminotransferase Spica_1209 IPR018300 Aminotransferase, class IV, conserved site Spica_1209 IPR036038 Aminotransferase-like, PLP-dependent enzymes Spica_1210 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_1210 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_1210 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase Spica_1210 IPR015424 Pyridoxal phosphate-dependent transferase Spica_1210 IPR000192 Aminotransferase class V domain Spica_1210 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site Spica_1213 IPR016169 FAD-binding, type PCMH, subdomain 2 Spica_1213 IPR005170 Transporter-associated domain Spica_1213 IPR036318 FAD-binding, type PCMH-like superfamily Spica_1213 IPR002550 CNNM, transmembrane domain Spica_1213 IPR000644 CBS domain Spica_1216 IPR004839 Aminotransferase, class I/classII Spica_1216 IPR015424 Pyridoxal phosphate-dependent transferase Spica_1216 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_1216 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_1218 IPR036138 Penicillin-binding protein, dimerisation domain superfamily Spica_1218 IPR005311 Penicillin-binding protein, dimerisation domain Spica_1218 IPR012338 Beta-lactamase/transpeptidase-like Spica_1218 IPR001460 Penicillin-binding protein, transpeptidase Spica_1219 IPR019533 Peptidase S26 Spica_1219 IPR000223 Peptidase S26A, signal peptidase I Spica_1219 IPR019758 Peptidase S26A, signal peptidase I, conserved site Spica_1219 IPR019757 Peptidase S26A, signal peptidase I, lysine active site Spica_1219 IPR036286 LexA/Signal peptidase-like superfamily Spica_1219 IPR019756 Peptidase S26A, signal peptidase I, serine active site Spica_1220 IPR016047 Peptidase M23 Spica_1220 IPR011055 Duplicated hybrid motif Spica_1222 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1222 IPR002716 PIN domain Spica_1222 IPR029060 PIN-like domain superfamily Spica_1222 IPR003714 PhoH-like protein Spica_1224 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel Spica_1224 IPR002509 NodB homology domain Spica_1224 IPR010916 TonB box, conserved site Spica_1224 IPR014228 Sporulation protein, polysaccharide deacetylase, YlxY Spica_1225 IPR004602 UvrABC system subunit A Spica_1225 IPR003439 ABC transporter-like Spica_1225 IPR017871 ABC transporter, conserved site Spica_1225 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1225 IPR041552 UvrA DNA-binding domain Spica_1225 IPR041102 UvrA, interaction domain Spica_1227 IPR036612 K Homology domain, type 1 superfamily Spica_1227 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1227 IPR004087 K Homology domain Spica_1227 IPR003714 PhoH-like protein Spica_1228 IPR003607 HD/PDEase domain Spica_1228 IPR006674 HD domain Spica_1228 IPR006675 HDIG domain Spica_1228 IPR011621 Metal-dependent phosphohydrolase, 7TM intracellular domain Spica_1228 IPR011624 Metal-dependent phosphohydrolase, 7TM extracellular domain Spica_1229 IPR002036 Endoribonuclease YbeY Spica_1229 IPR023091 Metalloprotease catalytic domain superfamily, predicted Spica_1229 IPR020549 Endoribonuclease YbeY, conserved site Spica_1230 IPR000644 CBS domain Spica_1230 IPR036318 FAD-binding, type PCMH-like superfamily Spica_1230 IPR016169 FAD-binding, type PCMH, subdomain 2 Spica_1230 IPR005170 Transporter-associated domain Spica_1236 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1236 IPR042101 Signal recognition particle SRP54, N-terminal domain superfamily Spica_1236 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain Spica_1236 IPR013822 Signal recognition particle SRP54, helical bundle Spica_1236 IPR003593 AAA+ ATPase domain Spica_1236 IPR036225 SRP/SRP receptor, N-terminal Spica_1236 IPR004390 Signal-recognition particle receptor FtsY Spica_1238 IPR025857 MacB-like periplasmic core domain Spica_1238 IPR011925 Lipoprotein-releasing system transmembrane protein LolC/E Spica_1238 IPR003838 ABC transporter permease protein domain Spica_1239 IPR017871 ABC transporter, conserved site Spica_1239 IPR003593 AAA+ ATPase domain Spica_1239 IPR003439 ABC transporter-like Spica_1239 IPR015854 ABC transporter, lipoprotein release, LolD Spica_1239 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1242 IPR023660 Protein arginine kinase Spica_1242 IPR000749 ATP:guanido phosphotransferase Spica_1242 IPR022415 ATP:guanido phosphotransferase active site Spica_1242 IPR022414 ATP:guanido phosphotransferase, catalytic domain Spica_1242 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain Spica_1243 IPR001943 UVR domain Spica_1243 IPR001270 ClpA/B family Spica_1243 IPR018368 ClpA/B, conserved site 1 Spica_1243 IPR028299 ClpA/B, conserved site 2 Spica_1243 IPR041546 ClpA/ClpB, AAA lid domain Spica_1243 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1243 IPR036628 Clp, N-terminal domain superfamily Spica_1243 IPR004176 Clp, N-terminal Spica_1243 IPR019489 Clp ATPase, C-terminal Spica_1243 IPR003959 ATPase, AAA-type, core Spica_1243 IPR003593 AAA+ ATPase domain Spica_1244 IPR012684 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit Spica_1244 IPR012686 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit Spica_1244 IPR011234 Fumarylacetoacetase-like, C-terminal Spica_1244 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily Spica_1246 IPR000889 Glutathione peroxidase Spica_1246 IPR029759 Glutathione peroxidase active site Spica_1246 IPR036249 Thioredoxin-like superfamily Spica_1246 IPR029760 Glutathione peroxidase conserved site Spica_1247 IPR036390 Winged helix DNA-binding domain superfamily Spica_1247 IPR000835 MarR-type HTH domain Spica_1247 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1249 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1249 IPR001650 Helicase, C-terminal Spica_1249 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1249 IPR011545 DEAD/DEAH box helicase domain Spica_1249 IPR018973 DEAD/DEAH-box helicase, putative Spica_1250 IPR038720 YprB, ribonuclease H-like domain Spica_1250 IPR011990 Tetratricopeptide-like helical domain superfamily Spica_1250 IPR012337 Ribonuclease H-like superfamily Spica_1251 IPR014016 UvrD-like helicase, ATP-binding domain Spica_1251 IPR005751 ATP-dependent DNA helicase PcrA Spica_1251 IPR013986 DExx box DNA helicase domain superfamily Spica_1251 IPR034739 UvrD/AddA helicase, N-terminal Spica_1251 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1251 IPR000212 DNA helicase, UvrD/REP type Spica_1251 IPR014017 UvrD-like DNA helicase, C-terminal Spica_1253 IPR000802 Arsenical pump membrane protein, ArsB Spica_1253 IPR004680 Citrate transporter-like domain Spica_1254 IPR020922 dITP/XTP pyrophosphatase Spica_1254 IPR002637 Ham1-like protein Spica_1254 IPR029001 Inosine triphosphate pyrophosphatase-like Spica_1258 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1258 IPR001650 Helicase, C-terminal Spica_1258 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1258 IPR014014 RNA helicase, DEAD-box type, Q motif Spica_1258 IPR011545 DEAD/DEAH box helicase domain Spica_1259 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Spica_1259 IPR001296 Glycosyl transferase, family 1 Spica_1260 IPR001734 Sodium/solute symporter Spica_1260 IPR018212 Sodium/solute symporter, conserved site Spica_1260 IPR011851 Sodium/proline symporter Spica_1260 IPR038377 Sodium/glucose symporter superfamily Spica_1264 IPR028154 AMP-dependent ligase, C-terminal Spica_1264 IPR000873 AMP-dependent synthetase/ligase Spica_1264 IPR042099 AMP-dependent synthetase-like superfamily Spica_1264 IPR011880 Phenylacetate-CoA ligase Spica_1266 IPR001296 Glycosyl transferase, family 1 Spica_1266 IPR011835 Bacterial/plant glycogen synthase Spica_1266 IPR013534 Starch synthase, catalytic domain Spica_1269 IPR002792 TRAM domain Spica_1269 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1269 IPR012340 Nucleic acid-binding, OB-fold Spica_1269 IPR030391 RNA methyltransferase TrmA, conserved site Spica_1269 IPR030390 RNA methyltransferase TrmA, active site Spica_1269 IPR010280 (Uracil-5)-methyltransferase family Spica_1270 IPR029058 Alpha/Beta hydrolase fold Spica_1270 IPR000073 Alpha/beta hydrolase fold-1 Spica_1270 IPR022742 Serine aminopeptidase, S33 Spica_1271 IPR002646 Poly A polymerase, head domain Spica_1271 IPR025866 Polymerase A arginine-rich C-terminal domain Spica_1271 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Spica_1271 IPR010206 Poly(A) polymerase I Spica_1274 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site Spica_1274 IPR006145 Pseudouridine synthase, RsuA/RluA Spica_1274 IPR002942 RNA-binding S4 domain Spica_1274 IPR036986 RNA-binding S4 domain superfamily Spica_1274 IPR006225 Pseudouridine synthase, RluC/RluD Spica_1274 IPR020103 Pseudouridine synthase, catalytic domain superfamily Spica_1278 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD Spica_1278 IPR011303 Ion-translocating oxidoreductase complex Rnf, subunit D Spica_1281 IPR003667 NqrDE/RnfAE Spica_1281 IPR011293 Ion-translocating oxidoreductase complex, subunit RnfA/RsxA Spica_1283 IPR015413 Methionyl/Leucyl tRNA synthetase Spica_1283 IPR014758 Methionyl-tRNA synthetase Spica_1283 IPR029038 Methionyl-tRNA synthetase, Zn-domain Spica_1283 IPR023458 Methionine-tRNA ligase, type 1 Spica_1283 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding Spica_1283 IPR041872 Methionyl-tRNA synthetase, anticodon-binding domain Spica_1283 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site Spica_1283 IPR002547 tRNA-binding domain Spica_1283 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1283 IPR012340 Nucleic acid-binding, OB-fold Spica_1283 IPR033911 Methioninyl-tRNA synthetase core domain Spica_1285 IPR013471 Ribonuclease Z/BN Spica_1285 IPR001279 Metallo-beta-lactamase Spica_1285 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_1286 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1286 IPR003593 AAA+ ATPase domain Spica_1286 IPR003439 ABC transporter-like Spica_1286 IPR017871 ABC transporter, conserved site Spica_1286 IPR025302 Domain of unknown function DUF4162 Spica_1298 IPR023620 Small protein B Spica_1298 IPR000037 SsrA-binding protein Spica_1298 IPR020081 SsrA-binding protein, conserved site Spica_1300 IPR019758 Peptidase S26A, signal peptidase I, conserved site Spica_1300 IPR036286 LexA/Signal peptidase-like superfamily Spica_1300 IPR000223 Peptidase S26A, signal peptidase I Spica_1300 IPR019757 Peptidase S26A, signal peptidase I, lysine active site Spica_1300 IPR019533 Peptidase S26 Spica_1300 IPR019756 Peptidase S26A, signal peptidase I, serine active site Spica_1302 IPR006638 Elp3/MiaB/NifB Spica_1302 IPR007197 Radical SAM Spica_1302 IPR034505 Anaerobic coproporphyrinogen-III oxidase Spica_1302 IPR004559 Heme chaperone HemW-like Spica_1302 IPR010723 HemN, C-terminal Spica_1302 IPR023404 Radical SAM, alpha/beta horseshoe Spica_1303 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1303 IPR007502 Helicase-associated domain Spica_1303 IPR011709 Domain of unknown function DUF1605 Spica_1303 IPR042035 DEAH helicase, winged-helix domain Spica_1303 IPR011545 DEAD/DEAH box helicase domain Spica_1303 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1303 IPR001650 Helicase, C-terminal Spica_1304 IPR040442 Pyruvate kinase-like domain superfamily Spica_1304 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily Spica_1304 IPR010121 Pyruvate, phosphate dikinase Spica_1304 IPR036637 Phosphohistidine domain superfamily Spica_1304 IPR023151 PEP-utilising enzyme, conserved site Spica_1304 IPR000121 PEP-utilising enzyme, C-terminal Spica_1304 IPR018274 PEP-utilising enzyme, active site Spica_1304 IPR013815 ATP-grasp fold, subdomain 1 Spica_1304 IPR008279 PEP-utilising enzyme, mobile domain Spica_1304 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding Spica_1307 IPR017871 ABC transporter, conserved site Spica_1307 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1307 IPR017875 Aliphatic sulfonates import ATP-binding protein SsuB Spica_1307 IPR003439 ABC transporter-like Spica_1307 IPR003593 AAA+ ATPase domain Spica_1309 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1309 IPR005876 Cobalt transport protein ATP-binding subunit Spica_1309 IPR015856 ABC transporter, CbiO/EcfA subunit Spica_1309 IPR017871 ABC transporter, conserved site Spica_1309 IPR003439 ABC transporter-like Spica_1309 IPR003593 AAA+ ATPase domain Spica_1310 IPR003784 BioY protein Spica_1311 IPR008988 Transcriptional repressor, C-terminal Spica_1311 IPR030855 Bifunctional ligase/repressor BirA Spica_1311 IPR004408 Biotin--acetyl-CoA-carboxylase ligase Spica_1311 IPR036390 Winged helix DNA-binding domain superfamily Spica_1311 IPR004409 Biotin operon repressor, helix-turn-helix domain Spica_1311 IPR003142 Biotin protein ligase, C-terminal Spica_1311 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain Spica_1311 IPR013196 Helix-turn-helix, type 11 Spica_1311 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1312 IPR003010 Carbon-nitrogen hydrolase Spica_1312 IPR004563 Apolipoprotein N-acyltransferase Spica_1312 IPR036526 Carbon-nitrogen hydrolase superfamily Spica_1313 IPR006206 Mevalonate/galactokinase Spica_1313 IPR036554 GHMP kinase, C-terminal domain superfamily Spica_1313 IPR013750 GHMP kinase, C-terminal domain Spica_1313 IPR019539 Galactokinase galactose-binding domain Spica_1313 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_1313 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_1313 IPR000705 Galactokinase Spica_1316 IPR005746 Thioredoxin Spica_1316 IPR013766 Thioredoxin domain Spica_1316 IPR017937 Thioredoxin, conserved site Spica_1316 IPR036249 Thioredoxin-like superfamily Spica_1317 IPR020536 Thil, AANH domain Spica_1317 IPR003720 tRNA sulfurtransferase ThiI Spica_1317 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1317 IPR004114 THUMP domain Spica_1318 IPR015424 Pyridoxal phosphate-dependent transferase Spica_1318 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_1318 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_1318 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site Spica_1318 IPR000192 Aminotransferase class V domain Spica_1318 IPR017772 Cysteine desulfurase NifS, bacterial/archaeal Spica_1318 IPR010240 Cysteine desulfurase IscS Spica_1318 IPR016454 Cysteine desulfurase Spica_1319 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1319 IPR001845 HTH ArsR-type DNA-binding domain Spica_1319 IPR036390 Winged helix DNA-binding domain superfamily Spica_1319 IPR011991 ArsR-like helix-turn-helix domain Spica_1320 IPR041743 Bifunctional aspartokinase/homoserine dehydrogenase, N-terminal catalytic domain Spica_1320 IPR002912 ACT domain Spica_1320 IPR001048 Aspartate/glutamate/uridylate kinase Spica_1320 IPR036393 Acetylglutamate kinase-like superfamily Spica_1320 IPR001341 Aspartate kinase Spica_1320 IPR018042 Aspartate kinase, conserved site Spica_1320 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I Spica_1320 IPR027795 CASTOR, ACT domain Spica_1320 IPR001342 Homoserine dehydrogenase, catalytic Spica_1320 IPR019811 Homoserine dehydrogenase, conserved site Spica_1320 IPR036291 NAD(P)-binding domain superfamily Spica_1320 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding Spica_1321 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_1321 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_1321 IPR004839 Aminotransferase, class I/classII Spica_1321 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site Spica_1321 IPR015424 Pyridoxal phosphate-dependent transferase Spica_1323 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site Spica_1323 IPR000715 Glycosyl transferase, family 4 Spica_1325 IPR012337 Ribonuclease H-like superfamily Spica_1325 IPR001584 Integrase, catalytic core Spica_1325 IPR025948 HTH-like domain Spica_1325 IPR036397 Ribonuclease H superfamily Spica_1326 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related Spica_1326 IPR011051 RmlC-like cupin domain superfamily Spica_1326 IPR014710 RmlC-like jelly roll fold Spica_1327 IPR036291 NAD(P)-binding domain superfamily Spica_1327 IPR005913 dTDP-4-dehydrorhamnose reductase family Spica_1327 IPR029903 RmlD-like substrate binding domain Spica_1328 IPR005888 dTDP-glucose 4,6-dehydratase Spica_1328 IPR036291 NAD(P)-binding domain superfamily Spica_1328 IPR016040 NAD(P)-binding domain Spica_1331 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily Spica_1331 IPR012649 Phosphonopyruvate hydrolase Spica_1331 IPR039556 ICL/PEPM domain Spica_1331 IPR040442 Pyruvate kinase-like domain superfamily Spica_1332 IPR017684 Phosphonopyruvate decarboxylase Spica_1332 IPR029061 Thiamin diphosphate-binding fold Spica_1332 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding Spica_1332 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain Spica_1333 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_1333 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_1333 IPR015424 Pyridoxal phosphate-dependent transferase Spica_1333 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase Spica_1333 IPR012703 2-aminoethylphosphonate--pyruvate transaminase Spica_1333 IPR000192 Aminotransferase class V domain Spica_1334 IPR006195 Aminoacyl-tRNA synthetase, class II Spica_1334 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit Spica_1334 IPR015807 Histidine-tRNA ligase Spica_1334 IPR041715 Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain Spica_1334 IPR036621 Anticodon-binding domain superfamily Spica_1335 IPR004619 Type III pantothenate kinase Spica_1337 IPR013785 Aldolase-type TIM barrel Spica_1337 IPR013974 SAF domain Spica_1337 IPR006190 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal Spica_1337 IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily Spica_1337 IPR013132 N-acetylneuraminic acid synthase, N-terminal Spica_1339 IPR017856 Integrase-like, N-terminal Spica_1339 IPR002876 Transcriptional regulator TACO1-like Spica_1339 IPR026564 Transcriptional regulator TACO1-like, domain 3 Spica_1339 IPR029072 YebC-like Spica_1340 IPR012337 Ribonuclease H-like superfamily Spica_1340 IPR020563 Crossover junction endodeoxyribonuclease RuvC, magnesium-binding site Spica_1340 IPR002176 Crossover junction endodeoxyribonuclease RuvC Spica_1340 IPR036397 Ribonuclease H superfamily Spica_1341 IPR012340 Nucleic acid-binding, OB-fold Spica_1341 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 Spica_1341 IPR000085 Bacterial DNA recombination protein RuvA Spica_1341 IPR010994 RuvA domain 2-like Spica_1341 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial Spica_1342 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1342 IPR008823 RuvB C-terminal winged helix domain Spica_1342 IPR008824 RuvB-like P-loop domain Spica_1342 IPR041445 RuvB, AAA lid domain Spica_1342 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1342 IPR004605 DNA helicase, Holliday junction RuvB-type Spica_1342 IPR003593 AAA+ ATPase domain Spica_1342 IPR036390 Winged helix DNA-binding domain superfamily Spica_1343 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA Spica_1343 IPR042118 QueA, domain 1 Spica_1343 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily Spica_1343 IPR042119 QueA, domain 2 Spica_1345 IPR039430 Thymidylate kinase-like domain Spica_1345 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1345 IPR018094 Thymidylate kinase Spica_1345 IPR018095 Thymidylate kinase, conserved site Spica_1347 IPR010827 POTRA domain, BamA/TamA-like Spica_1347 IPR023707 Outer membrane protein assembly factor BamA Spica_1347 IPR034746 POTRA domain Spica_1347 IPR000184 Bacterial surface antigen (D15) Spica_1347 IPR039910 Surface antigen D15-like Spica_1350 IPR036187 DNA mismatch repair protein MutS, core domain superfamily Spica_1350 IPR007696 DNA mismatch repair protein MutS, core Spica_1350 IPR036678 MutS, connector domain superfamily Spica_1350 IPR017261 DNA mismatch repair protein MutS/MSH Spica_1350 IPR007860 DNA mismatch repair protein MutS, connector domain Spica_1350 IPR016151 DNA mismatch repair protein MutS, N-terminal Spica_1350 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1350 IPR007695 DNA mismatch repair protein MutS-like, N-terminal Spica_1350 IPR007861 DNA mismatch repair protein MutS, clamp Spica_1350 IPR000432 DNA mismatch repair protein MutS, C-terminal Spica_1350 IPR005748 DNA mismatch repair protein MutS Spica_1351 IPR000836 Phosphoribosyltransferase domain Spica_1351 IPR023050 Bifunctional protein PyrR Spica_1351 IPR029057 Phosphoribosyltransferase-like Spica_1352 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily Spica_1352 IPR035956 RimP, N-terminal domain superfamily Spica_1352 IPR028989 Ribosome maturation factor RimP, N-terminal Spica_1352 IPR003728 Ribosome maturation factor RimP Spica_1352 IPR028998 Ribosome maturation factor RimP, C-terminal Spica_1353 IPR012340 Nucleic acid-binding, OB-fold Spica_1353 IPR030842 Transcription termination/antitermination protein NusA, bacterial Spica_1353 IPR036555 NusA, N-terminal domain superfamily Spica_1353 IPR003029 S1 domain Spica_1353 IPR022967 RNA-binding domain, S1 Spica_1353 IPR025249 KH domain, NusA-like Spica_1353 IPR013735 Transcription factor NusA, N-terminal Spica_1353 IPR015946 K homology domain-like, alpha/beta Spica_1353 IPR004087 K Homology domain Spica_1353 IPR009019 K homology domain superfamily, prokaryotic type Spica_1353 IPR010213 Transcription termination factor NusA Spica_1354 IPR006847 Translation initiation factor IF-2, N-terminal Spica_1354 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1354 IPR005225 Small GTP-binding protein domain Spica_1354 IPR000795 Transcription factor, GTP-binding domain Spica_1354 IPR000178 Translation initiation factor aIF-2, bacterial-like Spica_1354 IPR015760 Translation initiation factor IF- 2 Spica_1354 IPR023115 Translation initiation factor IF- 2, domain 3 Spica_1354 IPR036925 Translation initiation factor IF-2, domain 3 superfamily Spica_1354 IPR009000 Translation protein, beta-barrel domain superfamily Spica_1355 IPR020053 Ribosome-binding factor A, conserved site Spica_1355 IPR023799 Ribosome-binding factor A domain superfamily Spica_1355 IPR000238 Ribosome-binding factor A Spica_1355 IPR015946 K homology domain-like, alpha/beta Spica_1356 IPR014780 tRNA pseudouridine synthase II, TruB Spica_1356 IPR020103 Pseudouridine synthase, catalytic domain superfamily Spica_1356 IPR002501 Pseudouridine synthase II, N-terminal Spica_1357 IPR000589 Ribosomal protein S15 Spica_1357 IPR005290 Ribosomal protein S15, bacterial-type Spica_1357 IPR009068 S15/NS1, RNA-binding Spica_1358 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_1358 IPR022967 RNA-binding domain, S1 Spica_1358 IPR036612 K Homology domain, type 1 superfamily Spica_1358 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain Spica_1358 IPR003029 S1 domain Spica_1358 IPR012162 Polyribonucleotide nucleotidyltransferase Spica_1358 IPR027408 PNPase/RNase PH domain superfamily Spica_1358 IPR012340 Nucleic acid-binding, OB-fold Spica_1358 IPR015847 Exoribonuclease, phosphorolytic domain 2 Spica_1358 IPR004087 K Homology domain Spica_1358 IPR001247 Exoribonuclease, phosphorolytic domain 1 Spica_1358 IPR036345 Exoribonuclease, PH domain 2 superfamily Spica_1358 IPR004088 K Homology domain, type 1 Spica_1359 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like Spica_1359 IPR007863 Peptidase M16, C-terminal Spica_1359 IPR001431 Peptidase M16, zinc-binding site Spica_1359 IPR011765 Peptidase M16, N-terminal Spica_1362 IPR002616 tRNA-guanine(15) transglycosylase-like Spica_1362 IPR004803 tRNA-guanine transglycosylase Spica_1362 IPR036511 Queuine tRNA-ribosyltransferase-like Spica_1365 IPR011990 Tetratricopeptide-like helical domain superfamily Spica_1367 IPR011060 Ribulose-phosphate binding barrel Spica_1367 IPR000056 Ribulose-phosphate 3-epimerase-like Spica_1367 IPR026019 Ribulose-phosphate 3-epimerase Spica_1367 IPR013785 Aldolase-type TIM barrel Spica_1371 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily Spica_1371 IPR003732 D-aminoacyl-tRNA deacylase DTD Spica_1372 IPR000836 Phosphoribosyltransferase domain Spica_1372 IPR005946 Ribose-phosphate pyrophosphokinase Spica_1372 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type Spica_1372 IPR029057 Phosphoribosyltransferase-like Spica_1372 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site Spica_1372 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain Spica_1373 IPR023400 DNA recombination and repair protein RecA, C-terminal Spica_1373 IPR020584 DNA recombination/repair protein RecA, conserved site Spica_1373 IPR020588 DNA recombination and repair protein RecA-like, ATP-binding domain Spica_1373 IPR013765 DNA recombination and repair protein RecA Spica_1373 IPR020587 DNA recombination and repair protein RecA, monomer-monomer interface Spica_1373 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1373 IPR003593 AAA+ ATPase domain Spica_1375 IPR023093 ScpA-like, C-terminal Spica_1375 IPR003768 Segregation and condensation protein A Spica_1376 IPR005234 Chromosome segregation/condensation protein ScpB Spica_1376 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1376 IPR036390 Winged helix DNA-binding domain superfamily Spica_1377 IPR036986 RNA-binding S4 domain superfamily Spica_1377 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F Spica_1377 IPR020103 Pseudouridine synthase, catalytic domain superfamily Spica_1377 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site Spica_1377 IPR042092 Pseudouridine synthase, RsuA/RluB/E/F, catalytic domain Spica_1377 IPR002942 RNA-binding S4 domain Spica_1377 IPR006145 Pseudouridine synthase, RsuA/RluA Spica_1378 IPR003136 Cytidylate kinase Spica_1378 IPR011994 Cytidylate kinase domain Spica_1378 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1379 IPR000110 Ribosomal protein S1 Spica_1379 IPR022967 RNA-binding domain, S1 Spica_1379 IPR003029 S1 domain Spica_1379 IPR012340 Nucleic acid-binding, OB-fold Spica_1380 IPR010113 Nif-specific regulatory protein Spica_1380 IPR002078 RNA polymerase sigma factor 54 interaction domain Spica_1380 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1380 IPR003593 AAA+ ATPase domain Spica_1380 IPR003018 GAF domain Spica_1380 IPR029016 GAF-like domain superfamily Spica_1380 IPR009057 Homeobox-like domain superfamily Spica_1380 IPR002197 DNA binding HTH domain, Fis-type Spica_1380 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_1380 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_1380 IPR025944 Sigma-54 interaction domain, conserved site Spica_1382 IPR029787 Nucleotide cyclase Spica_1382 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase Spica_1385 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site Spica_1385 IPR011923 Probable peptidoglycan glycosyltransferase RodA/MrdB Spica_1385 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA Spica_1386 IPR017790 Penicillin-binding protein 2 Spica_1386 IPR001460 Penicillin-binding protein, transpeptidase Spica_1386 IPR005311 Penicillin-binding protein, dimerisation domain Spica_1386 IPR012338 Beta-lactamase/transpeptidase-like Spica_1386 IPR036138 Penicillin-binding protein, dimerisation domain superfamily Spica_1388 IPR042175 Cell/Rod shape-determining protein MreC, domain 2 Spica_1388 IPR007221 Rod shape-determining protein MreC Spica_1388 IPR042177 Cell/Rod shape-determining protein MreC, domain 1 Spica_1389 IPR004753 Cell shape determining protein MreB Spica_1392 IPR007627 RNA polymerase sigma-70 region 2 Spica_1392 IPR007624 RNA polymerase sigma-70 region 3 Spica_1392 IPR014284 RNA polymerase sigma-70 like domain Spica_1392 IPR007630 RNA polymerase sigma-70 region 4 Spica_1392 IPR007127 RNA polymerase sigma factor 70, region 1.1 Spica_1392 IPR028630 RNA polymerase sigma factor RpoD Spica_1392 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1392 IPR000943 RNA polymerase sigma-70 Spica_1392 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_1392 IPR012760 RNA polymerase sigma factor RpoD, C-terminal Spica_1392 IPR013325 RNA polymerase sigma factor, region 2 Spica_1392 IPR009042 RNA polymerase sigma-70 region 1.2 Spica_1393 IPR030846 DNA primase DnaG, bacteria Spica_1393 IPR002694 Zinc finger, CHC2-type Spica_1393 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily Spica_1393 IPR013264 DNA primase, catalytic core, N-terminal Spica_1393 IPR036977 DNA Primase, CHC2-type zinc finger Spica_1393 IPR006295 DNA primase, DnaG Spica_1393 IPR034151 Bacterial DnaG primase, TOPRIM domain Spica_1393 IPR006171 TOPRIM domain Spica_1394 IPR003770 Endolytic murein transglycosylase Spica_1395 IPR034216 C5a peptidase-like domain Spica_1395 IPR019931 LPXTG cell wall anchor domain Spica_1395 IPR023828 Peptidase S8, subtilisin, Ser-active site Spica_1395 IPR013783 Immunoglobulin-like fold Spica_1395 IPR022398 Peptidase S8, subtilisin, His-active site Spica_1395 IPR023827 Peptidase S8, subtilisin, Asp-active site Spica_1395 IPR036852 Peptidase S8/S53 domain superfamily Spica_1395 IPR000209 Peptidase S8/S53 domain Spica_1395 IPR003137 PA domain Spica_1395 IPR010435 Fn3-like domain Spica_1395 IPR015500 Peptidase S8, subtilisin-related Spica_1397 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_1397 IPR013471 Ribonuclease Z/BN Spica_1397 IPR001279 Metallo-beta-lactamase Spica_1401 IPR011146 HIT-like domain Spica_1401 IPR036265 HIT-like superfamily Spica_1401 IPR001310 Histidine triad (HIT) protein Spica_1401 IPR039383 FHIT family Spica_1403 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Spica_1403 IPR002646 Poly A polymerase, head domain Spica_1403 IPR023068 CCA-adding enzyme, firmicutes Spica_1403 IPR032810 CCA-adding enzyme, C-terminal Spica_1404 IPR011907 Ribonuclease III Spica_1404 IPR036389 Ribonuclease III, endonuclease domain superfamily Spica_1404 IPR000999 Ribonuclease III domain Spica_1404 IPR014720 Double-stranded RNA-binding domain Spica_1405 IPR036736 ACP-like superfamily Spica_1405 IPR009081 Phosphopantetheine binding ACP domain Spica_1405 IPR003231 Acyl carrier protein (ACP) Spica_1406 IPR002677 Ribosomal protein L32p Spica_1406 IPR011332 Zinc-binding ribosomal protein Spica_1407 IPR001980 Phosphopantetheine adenylyltransferase Spica_1407 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1407 IPR004821 Cytidyltransferase-like domain Spica_1409 IPR011989 Armadillo-like helical Spica_1409 IPR016024 Armadillo-type fold Spica_1412 IPR016195 Polymerase/histidinol phosphatase-like Spica_1412 IPR003141 Polymerase/histidinol phosphatase, N-terminal Spica_1412 IPR004013 PHP domain Spica_1412 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type Spica_1412 IPR029460 DNA polymerase, helix-hairpin-helix motif Spica_1412 IPR040982 DNA polymerase III alpha subunit finger domain Spica_1412 IPR041931 Bacterial DNA polymerase III alpha subunit, thumb domain Spica_1412 IPR011708 Bacterial DNA polymerase III, alpha subunit, NTPase domain Spica_1412 IPR004805 DNA polymerase III, alpha subunit Spica_1415 IPR001865 Ribosomal protein S2 Spica_1415 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily Spica_1415 IPR018130 Ribosomal protein S2, conserved site Spica_1415 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid Spica_1416 IPR009060 UBA-like superfamily Spica_1416 IPR018101 Translation elongation factor Ts, conserved site Spica_1416 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation Spica_1416 IPR001816 Translation elongation factor EFTs/EF1B Spica_1416 IPR036402 Elongation factor Ts, dimerisation domain superfamily Spica_1417 IPR023584 Ribosome recycling factor domain Spica_1417 IPR002661 Ribosome recycling factor Spica_1417 IPR036191 RRF superfamily Spica_1418 IPR036424 Decaprenyl diphosphate synthase-like superfamily Spica_1418 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site Spica_1418 IPR001441 Decaprenyl diphosphate synthase-like Spica_1419 IPR000374 Phosphatidate cytidylyltransferase Spica_1420 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal Spica_1420 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal Spica_1420 IPR026877 DXP reductoisomerase C-terminal domain Spica_1420 IPR036291 NAD(P)-binding domain superfamily Spica_1420 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase Spica_1420 IPR036169 DXP reductoisomerase, C-terminal domain superfamily Spica_1421 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase Spica_1421 IPR008915 Peptidase M50 Spica_1421 IPR036034 PDZ superfamily Spica_1421 IPR001478 PDZ domain Spica_1421 IPR041489 PDZ domain 6 Spica_1424 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily Spica_1424 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1424 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal Spica_1424 IPR007693 DNA helicase, DnaB-like, N-terminal Spica_1424 IPR007694 DNA helicase, DnaB-like, C-terminal Spica_1424 IPR007692 DNA helicase, DnaB type Spica_1425 IPR020594 Ribosomal protein L9, bacteria/chloroplast Spica_1425 IPR020070 Ribosomal protein L9, N-terminal Spica_1425 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Spica_1425 IPR000244 Ribosomal protein L9 Spica_1425 IPR020069 Ribosomal protein L9, C-terminal Spica_1425 IPR036791 Ribosomal protein L9, C-terminal domain superfamily Spica_1425 IPR009027 Ribosomal protein L9/RNase H1, N-terminal Spica_1427 IPR001648 Ribosomal protein S18 Spica_1427 IPR018275 Ribosomal protein S18, conserved site Spica_1427 IPR036870 Ribosomal protein S18 superfamily Spica_1428 IPR000424 Primosome PriB/single-strand DNA-binding Spica_1428 IPR011344 Single-stranded DNA-binding protein Spica_1428 IPR012340 Nucleic acid-binding, OB-fold Spica_1429 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 Spica_1429 IPR035980 Ribosomal protein S6 superfamily Spica_1429 IPR020815 Ribosomal protein S6, conserved site Spica_1429 IPR020814 Ribosomal protein S6, plastid/chloroplast Spica_1429 IPR000529 Ribosomal protein S6 Spica_1432 IPR025714 Methyltransferase domain Spica_1432 IPR002052 DNA methylase, N-6 adenine-specific, conserved site Spica_1432 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1432 IPR022882 tRNA1(Val) (adenine(37)-N6)-methyltransferase Spica_1435 IPR013785 Aldolase-type TIM barrel Spica_1435 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr Spica_1435 IPR027492 Dual-specificity RNA methyltransferase RlmN Spica_1435 IPR007197 Radical SAM Spica_1435 IPR040072 Methyltransferase (Class A) Spica_1438 IPR003561 Mutator MutT Spica_1438 IPR020084 NUDIX hydrolase, conserved site Spica_1438 IPR020476 NUDIX hydrolase Spica_1438 IPR000086 NUDIX hydrolase domain Spica_1438 IPR015797 NUDIX hydrolase-like domain superfamily Spica_1441 IPR029056 Ribokinase-like Spica_1441 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr Spica_1441 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase Spica_1441 IPR017953 Carbohydrate kinase, predicted, conserved site Spica_1441 IPR004443 YjeF N-terminal domain Spica_1441 IPR036652 YjeF N-terminal domain superfamily Spica_1443 IPR004027 SEC-C motif Spica_1443 IPR000185 Protein translocase subunit SecA Spica_1443 IPR020937 SecA conserved site Spica_1443 IPR011115 SecA DEAD-like, N-terminal Spica_1443 IPR014018 SecA motor DEAD Spica_1443 IPR011130 SecA, preprotein cross-linking domain Spica_1443 IPR011116 SecA Wing/Scaffold Spica_1443 IPR036266 SecA, Wing/Scaffold superfamily Spica_1443 IPR036670 SecA, preprotein cross-linking domain superfamily Spica_1443 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1447 IPR036291 NAD(P)-binding domain superfamily Spica_1447 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain Spica_1447 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1448 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase Spica_1448 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_1448 IPR015424 Pyridoxal phosphate-dependent transferase Spica_1448 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_1449 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead Spica_1449 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site Spica_1449 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding Spica_1449 IPR037165 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily Spica_1449 IPR012675 Beta-grasp domain superfamily Spica_1449 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain Spica_1449 IPR036010 2Fe-2S ferredoxin-like superfamily Spica_1449 IPR002888 [2Fe-2S]-binding Spica_1449 IPR036856 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily Spica_1449 IPR036884 [2Fe-2S]-binding domain superfamily Spica_1450 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site Spica_1450 IPR012675 Beta-grasp domain superfamily Spica_1450 IPR002888 [2Fe-2S]-binding Spica_1450 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain Spica_1450 IPR036884 [2Fe-2S]-binding domain superfamily Spica_1450 IPR036010 2Fe-2S ferredoxin-like superfamily Spica_1453 IPR016037 3-dehydroquinate synthase AroB Spica_1453 IPR030963 3-dehydroquinate synthase family Spica_1453 IPR030960 3-dehydroquinate synthase domain Spica_1455 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type Spica_1455 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily Spica_1455 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation Spica_1455 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Spica_1455 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal Spica_1455 IPR017476 UDP-glucose/GDP-mannose dehydrogenase Spica_1455 IPR036291 NAD(P)-binding domain superfamily Spica_1455 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal Spica_1456 IPR039421 Type I protein exporter Spica_1456 IPR003593 AAA+ ATPase domain Spica_1456 IPR011527 ABC transporter type 1, transmembrane domain Spica_1456 IPR036640 ABC transporter type 1, transmembrane domain superfamily Spica_1456 IPR003439 ABC transporter-like Spica_1456 IPR017871 ABC transporter, conserved site Spica_1456 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1459 IPR001173 Glycosyltransferase 2-like Spica_1459 IPR029044 Nucleotide-diphospho-sugar transferases Spica_1461 IPR007074 LicD family Spica_1469 IPR036291 NAD(P)-binding domain superfamily Spica_1469 IPR001509 NAD-dependent epimerase/dehydratase Spica_1470 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase Spica_1470 IPR003362 Bacterial sugar transferase Spica_1470 IPR017472 Undecaprenyl-phosphate galactose phosphotransferase, WbaP Spica_1473 IPR020013 Flagellar hook-basal body protein, FlgE/F/G Spica_1473 IPR001444 Flagellar basal body rod protein, N-terminal Spica_1473 IPR019776 Flagellar basal body rod protein, conserved site Spica_1473 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Spica_1473 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like Spica_1473 IPR012834 Flagellar basal-body rod FlgG Spica_1474 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Spica_1474 IPR012834 Flagellar basal-body rod FlgG Spica_1474 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like Spica_1474 IPR020013 Flagellar hook-basal body protein, FlgE/F/G Spica_1474 IPR019776 Flagellar basal body rod protein, conserved site Spica_1474 IPR001444 Flagellar basal body rod protein, N-terminal Spica_1477 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal Spica_1477 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1477 IPR010225 ATP-dependent helicase HrpB Spica_1477 IPR001650 Helicase, C-terminal Spica_1477 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1477 IPR011545 DEAD/DEAH box helicase domain Spica_1477 IPR007502 Helicase-associated domain Spica_1480 IPR036420 BRCT domain superfamily Spica_1480 IPR010994 RuvA domain 2-like Spica_1480 IPR004150 NAD-dependent DNA ligase, OB-fold Spica_1480 IPR012340 Nucleic acid-binding, OB-fold Spica_1480 IPR013840 NAD-dependent DNA ligase, N-terminal Spica_1480 IPR013839 NAD-dependent DNA ligase, adenylation Spica_1480 IPR001357 BRCT domain Spica_1480 IPR001679 NAD-dependent DNA ligase Spica_1480 IPR018239 NAD-dependent DNA ligase, active site Spica_1481 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1481 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type Spica_1495 IPR029057 Phosphoribosyltransferase-like Spica_1495 IPR000836 Phosphoribosyltransferase domain Spica_1498 IPR011005 Dihydropteroate synthase-like Spica_1498 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial Spica_1498 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type Spica_1500 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family Spica_1501 IPR002699 ATPase, V1 complex, subunit D Spica_1502 IPR022879 V-type ATP synthase regulatory subunit B/beta Spica_1502 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain Spica_1502 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain Spica_1502 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1503 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site Spica_1503 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain Spica_1503 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1503 IPR022878 V-type ATP synthase catalytic alpha chain Spica_1503 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily Spica_1503 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension Spica_1503 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain Spica_1503 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal Spica_1505 IPR002842 V-type ATPase subunit E Spica_1505 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Spica_1507 IPR014718 Glycoside hydrolase-type carbohydrate-binding Spica_1507 IPR011013 Galactose mutarotase-like domain superfamily Spica_1507 IPR018052 Aldose 1-epimerase, conserved site Spica_1507 IPR015443 Aldose 1-epimerase Spica_1507 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase Spica_1508 IPR036869 Chaperone J-domain superfamily Spica_1508 IPR001623 DnaJ domain Spica_1509 IPR025944 Sigma-54 interaction domain, conserved site Spica_1509 IPR002078 RNA polymerase sigma factor 54 interaction domain Spica_1509 IPR002197 DNA binding HTH domain, Fis-type Spica_1509 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1509 IPR001789 Signal transduction response regulator, receiver domain Spica_1509 IPR011006 CheY-like superfamily Spica_1509 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_1509 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_1509 IPR009057 Homeobox-like domain superfamily Spica_1509 IPR003593 AAA+ ATPase domain Spica_1510 IPR035965 PAS domain superfamily Spica_1510 IPR005467 Histidine kinase domain Spica_1510 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1510 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1510 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_1510 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_1510 IPR013767 PAS fold Spica_1510 IPR000014 PAS domain Spica_1510 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_1511 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1511 IPR012763 DNA polymerase III, subunit gamma/ tau Spica_1511 IPR003593 AAA+ ATPase domain Spica_1511 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal Spica_1511 IPR022754 DNA polymerase III, gamma subunit, domain III Spica_1512 IPR003825 Colicin V production, CvpA Spica_1513 IPR006009 N-acetylglucosaminyltransferase, MurG Spica_1513 IPR007235 Glycosyl transferase, family 28, C-terminal Spica_1513 IPR004276 Glycosyltransferase family 28, N-terminal domain Spica_1515 IPR003660 HAMP domain Spica_1515 IPR029787 Nucleotide cyclase Spica_1515 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase Spica_1517 IPR036061 CheW-like domain superfamily Spica_1517 IPR039315 Chemotaxis protein CheW Spica_1517 IPR002545 CheW-like domain Spica_1521 IPR012845 RNA polymerase sigma factor, FliA/WhiG Spica_1521 IPR013324 RNA polymerase sigma factor, region 3/4-like Spica_1521 IPR014284 RNA polymerase sigma-70 like domain Spica_1521 IPR000943 RNA polymerase sigma-70 Spica_1521 IPR007627 RNA polymerase sigma-70 region 2 Spica_1521 IPR007624 RNA polymerase sigma-70 region 3 Spica_1521 IPR007630 RNA polymerase sigma-70 region 4 Spica_1521 IPR013325 RNA polymerase sigma factor, region 2 Spica_1523 IPR025501 ATP binding protein MinD Spica_1523 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1523 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 Spica_1524 IPR020006 Flagellar biosynthesis protein FlhF Spica_1524 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain Spica_1524 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1524 IPR003593 AAA+ ATPase domain Spica_1525 IPR042193 FHIPEP, domain 3 Spica_1525 IPR042196 FHIPEP, domain 4 Spica_1525 IPR042194 FHIPEP, domain 1 Spica_1525 IPR001712 Type III secretion system FHIPEP Spica_1525 IPR006301 Flagellar biosynthesis protein FlhA Spica_1525 IPR025505 FHIPEP conserved site Spica_1526 IPR006135 Type III secretion system substrate exporter Spica_1526 IPR006136 Flagellar biosynthetic protein FlhB Spica_1526 IPR029025 Type III secretion system substrate exporter, C-terminal Spica_1527 IPR002010 Type III secretion system inner membrane R protein Spica_1527 IPR006303 Flagellar biosynthesis protein FliR Spica_1528 IPR002191 Bacterial export protein family 3 Spica_1528 IPR006305 Flagellar biosynthesis protein FliQ Spica_1529 IPR005838 Type III secretion system inner membrane P protein Spica_1529 IPR005837 Flagellar transport protein FliP Spica_1531 IPR036429 SpoA-like superfamily Spica_1531 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb Spica_1531 IPR012826 Flagellar motor switch FliN Spica_1531 IPR028976 CheC-like superfamily Spica_1531 IPR007597 CheC-like protein Spica_1531 IPR001543 Surface presentation of antigen (SpoA) Spica_1532 IPR001689 Flagellar motor switch protein FliM Spica_1532 IPR028976 CheC-like superfamily Spica_1532 IPR001543 Surface presentation of antigen (SpoA) Spica_1532 IPR036429 SpoA-like superfamily Spica_1533 IPR005503 Flagellar basal body-associated protein FliL Spica_1534 IPR025713 Motility protein B, N-terminal domain Spica_1534 IPR006665 OmpA-like domain Spica_1534 IPR036737 OmpA-like domain superfamily Spica_1535 IPR000540 Flagellar motor protein MotA, conserved site Spica_1535 IPR002898 MotA/TolQ/ExbB proton channel Spica_1536 IPR009384 Swarming motility protein SwrD-like Spica_1537 IPR001444 Flagellar basal body rod protein, N-terminal Spica_1537 IPR011491 Flagellar hook protein FlgE Spica_1537 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like Spica_1537 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Spica_1537 IPR037058 Flagellar hook protein FlgE superfamily Spica_1537 IPR019776 Flagellar basal body rod protein, conserved site Spica_1537 IPR020013 Flagellar hook-basal body protein, FlgE/F/G Spica_1538 IPR005648 Flagellar hook capping protein Spica_1542 IPR022830 Indigoidine synthase A-like Spica_1542 IPR007342 Pseudouridine-5'-phosphate glycosidase Spica_1543 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site Spica_1543 IPR029056 Ribokinase-like Spica_1543 IPR011611 Carbohydrate kinase PfkB Spica_1545 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily Spica_1545 IPR023753 FAD/NAD(P)-binding domain Spica_1545 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1545 IPR023536 Coenzyme A disulphide reductase, staphyolococci Spica_1545 IPR017758 Coenzyme A disulphide reductase Spica_1545 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Spica_1546 IPR036393 Acetylglutamate kinase-like superfamily Spica_1546 IPR002912 ACT domain Spica_1546 IPR036291 NAD(P)-binding domain superfamily Spica_1546 IPR001342 Homoserine dehydrogenase, catalytic Spica_1546 IPR027795 CASTOR, ACT domain Spica_1546 IPR011147 Bifunctional aspartokinase/homoserine dehydrogenase I Spica_1546 IPR018042 Aspartate kinase, conserved site Spica_1546 IPR001341 Aspartate kinase Spica_1546 IPR019811 Homoserine dehydrogenase, conserved site Spica_1546 IPR001048 Aspartate/glutamate/uridylate kinase Spica_1546 IPR041743 Bifunctional aspartokinase/homoserine dehydrogenase, N-terminal catalytic domain Spica_1546 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding Spica_1551 IPR031807 HicB-like antitoxin of toxin-antitoxin system Spica_1551 IPR035069 TTHA1013/TTHA0281-like Spica_1552 IPR035996 Tetrapyrrole methylase superfamily Spica_1552 IPR014777 Tetrapyrrole methylase, subdomain 1 Spica_1552 IPR000878 Tetrapyrrole methylase Spica_1552 IPR014776 Tetrapyrrole methylase, subdomain 2 Spica_1552 IPR018063 SAM-dependent methyltransferase RsmI, conserved site Spica_1552 IPR008189 rRNA small subunit methyltransferase I Spica_1553 IPR005273 Uracil-DNA glycosylase family 4 Spica_1553 IPR005122 Uracil-DNA glycosylase-like Spica_1553 IPR036895 Uracil-DNA glycosylase-like domain superfamily Spica_1554 IPR001650 Helicase, C-terminal Spica_1554 IPR011545 DEAD/DEAH box helicase domain Spica_1554 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1554 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1554 IPR040498 PriA DNA helicase, Cys-rich region (CRR) domain Spica_1554 IPR041222 Primosomal protein N', 3' DNA-binding domain Spica_1554 IPR042115 Primosomal protein N', 3' DNA-binding domain superfamily Spica_1554 IPR041236 Primosomal protein N, C-terminal domain Spica_1554 IPR005259 Primosomal protein N' Spica_1557 IPR001367 Iron dependent repressor, metal binding and dimerisation domain Spica_1557 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily Spica_1557 IPR022897 HTH-type transcription regulator MntR Spica_1557 IPR022689 Iron dependent repressor Spica_1557 IPR022687 DTXR-type HTH domain Spica_1557 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1557 IPR036390 Winged helix DNA-binding domain superfamily Spica_1558 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase Spica_1558 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1560 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal Spica_1560 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily Spica_1560 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic Spica_1560 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like Spica_1561 IPR003805 Adenosylcobinamide-GDP ribazoletransferase Spica_1562 IPR023545 rRNA small subunit methyltransferase F Spica_1562 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1562 IPR023267 RNA (C5-cytosine) methyltransferase Spica_1562 IPR011023 Nop2p Spica_1562 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain Spica_1562 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type Spica_1562 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Spica_1562 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site Spica_1563 IPR018211 Alcohol dehydrogenase, iron-type, conserved site Spica_1563 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA Spica_1564 IPR006153 Cation/H+ exchanger Spica_1564 IPR006037 Regulator of K+ conductance, C-terminal Spica_1564 IPR016169 FAD-binding, type PCMH, subdomain 2 Spica_1564 IPR036318 FAD-binding, type PCMH-like superfamily Spica_1564 IPR030151 K(+)/H(+) antiporter NhaP Spica_1564 IPR038770 Sodium/solute symporter superfamily Spica_1564 IPR005170 Transporter-associated domain Spica_1564 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily Spica_1574 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_1574 IPR007329 FMN-binding Spica_1574 IPR011399 Nitrous oxide reductase expression regulator NosR Spica_1575 IPR015797 NUDIX hydrolase-like domain superfamily Spica_1575 IPR029119 MutY, C-terminal Spica_1575 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Spica_1575 IPR000445 Helix-hairpin-helix motif Spica_1575 IPR003265 HhH-GPD domain Spica_1575 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif Spica_1575 IPR011257 DNA glycosylase Spica_1575 IPR005760 A/G-specific adenine glycosylase MutY Spica_1577 IPR011994 Cytidylate kinase domain Spica_1577 IPR011892 Cytidylate kinase, putative Spica_1577 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1578 IPR013551 Domain of unknown function DUF1732 Spica_1578 IPR005229 Conserved hypothetical protein CHP00255 Spica_1578 IPR013527 YicC-like, N-terminal Spica_1579 IPR005758 UDP-N-acetylmuramate--L-alanine ligase Spica_1579 IPR013221 Mur ligase, central Spica_1579 IPR036615 Mur ligase, C-terminal domain superfamily Spica_1579 IPR004101 Mur ligase, C-terminal Spica_1579 IPR036565 Mur-like, catalytic domain superfamily Spica_1579 IPR000713 Mur ligase, N-terminal catalytic domain Spica_1580 IPR001645 Folylpolyglutamate synthetase Spica_1580 IPR013221 Mur ligase, central Spica_1580 IPR036615 Mur ligase, C-terminal domain superfamily Spica_1580 IPR004101 Mur ligase, C-terminal Spica_1580 IPR036565 Mur-like, catalytic domain superfamily Spica_1580 IPR018109 Folylpolyglutamate synthetase, conserved site Spica_1581 IPR005467 Histidine kinase domain Spica_1581 IPR022066 Signal transduction histidine kinase, N-terminal Spica_1581 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_1581 IPR035965 PAS domain superfamily Spica_1581 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1581 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1581 IPR038424 Signal transduction histidine kinase, N-terminal domain superfamily Spica_1582 IPR036986 RNA-binding S4 domain superfamily Spica_1582 IPR002942 RNA-binding S4 domain Spica_1582 IPR006145 Pseudouridine synthase, RsuA/RluA Spica_1582 IPR006225 Pseudouridine synthase, RluC/RluD Spica_1582 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site Spica_1582 IPR020103 Pseudouridine synthase, catalytic domain superfamily Spica_1583 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site Spica_1583 IPR006145 Pseudouridine synthase, RsuA/RluA Spica_1583 IPR020103 Pseudouridine synthase, catalytic domain superfamily Spica_1583 IPR006225 Pseudouridine synthase, RluC/RluD Spica_1585 IPR011078 Pyridoxal phosphate homeostasis protein Spica_1585 IPR029066 PLP-binding barrel Spica_1585 IPR001608 Alanine racemase, N-terminal Spica_1586 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm Spica_1586 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site Spica_1586 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal Spica_1586 IPR011530 Ribosomal RNA adenine dimethylase Spica_1586 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1586 IPR023165 rRNA adenine dimethylase-like Spica_1591 IPR023555 Thiol-disulphide oxidoreductase ResA Spica_1591 IPR036249 Thioredoxin-like superfamily Spica_1591 IPR017937 Thioredoxin, conserved site Spica_1591 IPR013766 Thioredoxin domain Spica_1591 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant Spica_1592 IPR003834 Cytochrome C biogenesis protein, transmembrane domain Spica_1595 IPR041128 Arginine decarboxylase, C-terminal helical Spica_1595 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal Spica_1595 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site Spica_1595 IPR040634 Arginine decarboxylase, helical bundle domain Spica_1595 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal Spica_1595 IPR029066 PLP-binding barrel Spica_1595 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site Spica_1595 IPR002985 Arginine decarboxylase Spica_1595 IPR000183 Ornithine/DAP/Arg decarboxylase Spica_1596 IPR036526 Carbon-nitrogen hydrolase superfamily Spica_1596 IPR004563 Apolipoprotein N-acyltransferase Spica_1596 IPR003010 Carbon-nitrogen hydrolase Spica_1597 IPR007466 Peptidyl-arginine deiminase, Porphyromonas-type Spica_1597 IPR017754 Agmatine deiminase Spica_1599 IPR004790 Isocitrate dehydrogenase NADP-dependent Spica_1599 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site Spica_1599 IPR024084 Isopropylmalate dehydrogenase-like domain Spica_1600 IPR009718 Rex DNA-binding, C-terminal domain Spica_1600 IPR036291 NAD(P)-binding domain superfamily Spica_1600 IPR022876 Redox-sensing transcriptional repressor Rex Spica_1600 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1600 IPR036390 Winged helix DNA-binding domain superfamily Spica_1600 IPR003781 CoA-binding Spica_1601 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1601 IPR019614 S-adenosylmethionine-dependent methyltransferase Spica_1603 IPR042105 Ribosomal protein L31 superfamily Spica_1603 IPR027491 Ribosomal protein L31 type A Spica_1603 IPR002150 Ribosomal protein L31 Spica_1603 IPR034704 L28p-like Spica_1604 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain Spica_1604 IPR003593 AAA+ ATPase domain Spica_1604 IPR004665 Transcription termination factor Rho Spica_1604 IPR011112 Rho termination factor, N-terminal Spica_1604 IPR011113 Rho termination factor, RNA-binding domain Spica_1604 IPR011129 Cold shock domain Spica_1604 IPR041703 Transcription termination factor Rho, ATP binding domain Spica_1604 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1604 IPR012340 Nucleic acid-binding, OB-fold Spica_1605 IPR008135 Competence-induced protein CinA Spica_1605 IPR036653 CinA-like, C-terminal Spica_1605 IPR036425 MoaB/Mog-like domain superfamily Spica_1605 IPR041424 CinA, KH domain Spica_1605 IPR008136 CinA, C-terminal Spica_1605 IPR001453 MoaB/Mog domain Spica_1608 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response Spica_1608 IPR039420 Transcriptional regulatory protein WalR-like Spica_1608 IPR001867 OmpR/PhoB-type DNA-binding domain Spica_1608 IPR011006 CheY-like superfamily Spica_1608 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1608 IPR001789 Signal transduction response regulator, receiver domain Spica_1609 IPR036526 Carbon-nitrogen hydrolase superfamily Spica_1609 IPR004563 Apolipoprotein N-acyltransferase Spica_1609 IPR003010 Carbon-nitrogen hydrolase Spica_1610 IPR020816 Histone-like DNA-binding protein, conserved site Spica_1610 IPR000119 Histone-like DNA-binding protein Spica_1610 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily Spica_1611 IPR036510 Ribosomal protein S20 superfamily Spica_1611 IPR002583 Ribosomal protein S20 Spica_1613 IPR010242 Transcription factor HTH, IscR Spica_1613 IPR000944 Transcription regulator Rrf2-type Spica_1613 IPR030489 Transcription regulator Rrf2-type, conserved site Spica_1613 IPR036390 Winged helix DNA-binding domain superfamily Spica_1613 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1615 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1615 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1615 IPR014013 Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type Spica_1615 IPR010614 DEAD2 Spica_1615 IPR006555 ATP-dependent helicase, C-terminal Spica_1615 IPR001650 Helicase, C-terminal Spica_1617 IPR002123 Phospholipid/glycerol acyltransferase Spica_1617 IPR004552 1-acyl-sn-glycerol-3-phosphate acyltransferase Spica_1618 IPR004576 Transcription-repair coupling factor Spica_1618 IPR041471 UvrB, interaction domain Spica_1618 IPR037235 TRCF-like, C-terminal domain Spica_1618 IPR005118 Transcription-repair-coupling factor, C-terminal domain Spica_1618 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1618 IPR001650 Helicase, C-terminal Spica_1618 IPR036101 CarD-like/TRCF domain superfamily Spica_1618 IPR003711 CarD-like/TRCF domain Spica_1618 IPR011545 DEAD/DEAH box helicase domain Spica_1618 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1623 IPR013760 DNA topoisomerase, type IIA-like domain superfamily Spica_1623 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal Spica_1623 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily Spica_1623 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta Spica_1624 IPR001241 DNA topoisomerase, type IIA Spica_1624 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1624 IPR006171 TOPRIM domain Spica_1624 IPR013760 DNA topoisomerase, type IIA-like domain superfamily Spica_1624 IPR002288 DNA gyrase B subunit, C-terminal Spica_1624 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_1624 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 Spica_1624 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_1624 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1624 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal Spica_1624 IPR018522 DNA topoisomerase, type IIA, conserved site Spica_1626 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_1626 IPR009022 Elongation factor G, domain III Spica_1626 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_1626 IPR041095 Elongation Factor G, domain II Spica_1626 IPR005225 Small GTP-binding protein domain Spica_1626 IPR004161 Translation elongation factor EFTu-like, domain 2 Spica_1626 IPR031157 Tr-type G domain, conserved site Spica_1626 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1626 IPR035647 EF-G domain III/V-like Spica_1626 IPR000640 Elongation factor EFG, domain V-like Spica_1626 IPR009000 Translation protein, beta-barrel domain superfamily Spica_1626 IPR035649 EFG, domain V Spica_1626 IPR004540 Translation elongation factor EFG/EF2 Spica_1626 IPR005517 Translation elongation factor EFG/EF2, domain IV Spica_1626 IPR000795 Transcription factor, GTP-binding domain Spica_1627 IPR002020 Citrate synthase Spica_1627 IPR016143 Citrate synthase-like, small alpha subdomain Spica_1627 IPR036969 Citrate synthase superfamily Spica_1627 IPR024176 Citrate synthase, bacterial-type Spica_1627 IPR016142 Citrate synthase-like, large alpha subdomain Spica_1627 IPR011278 2-methylcitrate synthase/citrate synthase type I Spica_1627 IPR019810 Citrate synthase active site Spica_1628 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) Spica_1628 IPR004522 Asparagine-tRNA ligase Spica_1628 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb Spica_1628 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type Spica_1628 IPR012340 Nucleic acid-binding, OB-fold Spica_1628 IPR006195 Aminoacyl-tRNA synthetase, class II Spica_1629 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily Spica_1629 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A Spica_1629 IPR015956 Penicillin-binding protein, C-terminal domain superfamily Spica_1629 IPR012338 Beta-lactamase/transpeptidase-like Spica_1629 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal Spica_1629 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal Spica_1630 IPR016369 Flagellar filament outer layer protein FlaA, Spirochaetes Spica_1630 IPR006714 Flagellar filament outer layer protein FlaA Spica_1632 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain Spica_1633 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain Spica_1633 IPR008948 L-Aspartase-like Spica_1633 IPR022761 Fumarate lyase, N-terminal Spica_1633 IPR024083 Fumarase/histidase, N-terminal Spica_1633 IPR000362 Fumarate lyase family Spica_1633 IPR009049 Argininosuccinate lyase Spica_1633 IPR011761 ATP-grasp fold Spica_1633 IPR003806 ATP-grasp fold, PylC-type Spica_1635 IPR029044 Nucleotide-diphospho-sugar transferases Spica_1635 IPR003329 Acylneuraminate cytidylyltransferase Spica_1637 IPR027608 Spirochetes SPASM protein Spica_1637 IPR023885 4Fe4S-binding SPASM domain Spica_1638 IPR003753 Exonuclease VII, large subunit Spica_1638 IPR025824 OB-fold nucleic acid binding domain Spica_1638 IPR020579 Exonuclease VII, large subunit, C-terminal Spica_1639 IPR003761 Exonuclease VII, small subunit Spica_1639 IPR037004 Exonuclease VII, small subunit superfamily Spica_1640 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_1640 IPR002099 DNA mismatch repair protein family, N-terminal Spica_1640 IPR013507 DNA mismatch repair protein, S5 domain 2-like Spica_1640 IPR020667 DNA mismatch repair protein, MutL Spica_1640 IPR014762 DNA mismatch repair, conserved site Spica_1640 IPR037198 MutL, C-terminal domain superfamily Spica_1640 IPR042121 MutL, C-terminal domain, regulatory subdomain Spica_1640 IPR042120 MutL, C-terminal domain, dimerisation subdomain Spica_1640 IPR014790 MutL, C-terminal, dimerisation Spica_1640 IPR038973 DNA mismatch repair protein MutL/Mlh/Pms Spica_1640 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_1640 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1643 IPR018228 Deoxyribonuclease, TatD-related, conserved site Spica_1643 IPR015991 Uncharacterised hydrolase TatD-type Spica_1643 IPR032466 Metal-dependent hydrolase Spica_1643 IPR001130 TatD family Spica_1646 IPR040577 Glutamine synthetase, C-terminal Spica_1646 IPR008146 Glutamine synthetase, catalytic domain Spica_1646 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain Spica_1646 IPR022147 Glutamine synthetase type III N-terminal Spica_1646 IPR027303 Glutamine synthetase, glycine-rich site Spica_1647 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Spica_1647 IPR011322 Nitrogen regulatory PII-like, alpha/beta Spica_1647 IPR002187 Nitrogen regulatory protein PII Spica_1647 IPR002332 Nitrogen regulatory protein P-II, urydylation site Spica_1647 IPR017918 Nitrogen regulatory protein PII, conserved site Spica_1648 IPR024041 Ammonium transporter AmtB-like domain Spica_1648 IPR018047 Ammonium transporter, conserved site Spica_1648 IPR001905 Ammonium transporter Spica_1648 IPR029020 Ammonium/urea transporter Spica_1649 IPR003593 AAA+ ATPase domain Spica_1649 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_1649 IPR003018 GAF domain Spica_1649 IPR029016 GAF-like domain superfamily Spica_1649 IPR009057 Homeobox-like domain superfamily Spica_1649 IPR002197 DNA binding HTH domain, Fis-type Spica_1649 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1649 IPR002078 RNA polymerase sigma factor 54 interaction domain Spica_1649 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_1649 IPR025944 Sigma-54 interaction domain, conserved site Spica_1650 IPR003706 CstA, N-terminal domain Spica_1650 IPR025299 CstA, C-terminal domain Spica_1652 IPR016300 Arsenical pump ATPase, ArsA/GET3 Spica_1652 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1652 IPR025723 Anion-transporting ATPase-like domain Spica_1655 IPR000524 Transcription regulator HTH, GntR Spica_1655 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1655 IPR036390 Winged helix DNA-binding domain superfamily Spica_1656 IPR006158 Cobalamin (vitamin B12)-binding domain Spica_1656 IPR036724 Cobalamin-binding domain superfamily Spica_1656 IPR006394 Glutamate mutase sigma subunit Spica_1657 IPR006230 Protein MutL Spica_1658 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic Spica_1658 IPR014714 Glutamate mutase E subunit, C-terminal domain superfamily Spica_1658 IPR006396 Glutamate mutase epsilon subunit Spica_1659 IPR022665 Methylaspartate ammonia-lyase, N-terminal Spica_1659 IPR029017 Enolase-like, N-terminal Spica_1659 IPR022662 Methylaspartate ammonia-lyase, C-terminal Spica_1659 IPR006395 Methylaspartate ammonia-lyase Spica_1659 IPR036849 Enolase-like, C-terminal domain superfamily Spica_1665 IPR012947 Threonyl/alanyl tRNA synthetase, SAD Spica_1665 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) Spica_1665 IPR033728 Threonine-tRNA ligase catalytic core domain Spica_1665 IPR004095 TGS Spica_1665 IPR006195 Aminoacyl-tRNA synthetase, class II Spica_1665 IPR002320 Threonine-tRNA ligase, class IIa Spica_1665 IPR036621 Anticodon-binding domain superfamily Spica_1665 IPR004154 Anticodon-binding Spica_1665 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily Spica_1667 IPR022426 Flagellum-specific ATP synthase FliI, clade 3 Spica_1667 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1667 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain Spica_1667 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site Spica_1667 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain Spica_1667 IPR005714 ATPase, type III secretion system, FliI/YscN Spica_1667 IPR032463 ATPase, type III secretion system, FliI Spica_1667 IPR040627 T3SS EscN ATPase, C-terminal Spica_1667 IPR003593 AAA+ ATPase domain Spica_1668 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE Spica_1669 IPR000090 Flagellar motor switch protein FliG Spica_1669 IPR032779 Flagellar motor switch protein FliG, middle domain Spica_1669 IPR028263 Flagellar motor switch protein FliG, N-terminal domain Spica_1669 IPR023087 Flagellar motor switch protein FliG, C-terminal Spica_1669 IPR011002 Flagellar motor switch protein FliG, alpha-helical Spica_1670 IPR013556 Flagellar M-ring C-terminal Spica_1670 IPR000067 Flagellar M-ring protein FliF Spica_1670 IPR006182 Secretory protein YscJ/FliF Spica_1671 IPR001624 Flagellar hook-basal body complex protein FliE Spica_1672 IPR001444 Flagellar basal body rod protein, N-terminal Spica_1672 IPR019776 Flagellar basal body rod protein, conserved site Spica_1672 IPR006299 Flagellar basal-body rod protein FlgC Spica_1672 IPR010930 Flagellar basal-body/hook protein, C-terminal domain Spica_1673 IPR019776 Flagellar basal body rod protein, conserved site Spica_1673 IPR006300 Flagellar basal-body rod protein FlgB Spica_1673 IPR001444 Flagellar basal body rod protein, N-terminal Spica_1674 IPR019489 Clp ATPase, C-terminal Spica_1674 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1674 IPR004491 Heat shock protein HslU Spica_1674 IPR003959 ATPase, AAA-type, core Spica_1674 IPR003593 AAA+ ATPase domain Spica_1675 IPR022281 ATP-dependent protease, HslV subunit Spica_1675 IPR029055 Nucleophile aminohydrolases, N-terminal Spica_1675 IPR001353 Proteasome, subunit alpha/beta Spica_1675 IPR023333 Proteasome B-type subunit Spica_1676 IPR023009 Tyrosine recombinase XerC/XerD Spica_1676 IPR011010 DNA breaking-rejoining enzyme, catalytic core Spica_1676 IPR013762 Integrase-like, catalytic domain superfamily Spica_1676 IPR002104 Integrase, catalytic domain Spica_1676 IPR010998 Integrase/recombinase, N-terminal Spica_1676 IPR004107 Integrase, SAM-like, N-terminal Spica_1677 IPR023406 DNA topoisomerase, type IA, active site Spica_1677 IPR034149 DNA topoisomerase 1, TOPRIM domain Spica_1677 IPR006171 TOPRIM domain Spica_1677 IPR028612 DNA topoisomerase I, type IA Spica_1677 IPR013497 DNA topoisomerase, type IA, central Spica_1677 IPR013498 DNA topoisomerase, type IA, zn finger Spica_1677 IPR003602 DNA topoisomerase, type IA, DNA-binding domain Spica_1677 IPR023405 DNA topoisomerase, type IA, core domain Spica_1677 IPR005733 DNA topoisomerase I, bacterial-type Spica_1677 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 Spica_1677 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 Spica_1677 IPR000380 DNA topoisomerase, type IA Spica_1677 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 Spica_1677 IPR003601 DNA topoisomerase, type IA, domain 2 Spica_1678 IPR003488 DNA recombination-mediator protein A Spica_1678 IPR041614 DprA, winged helix domain Spica_1678 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1680 IPR023009 Tyrosine recombinase XerC/XerD Spica_1680 IPR011932 Tyrosine recombinase XerD Spica_1680 IPR004107 Integrase, SAM-like, N-terminal Spica_1680 IPR010998 Integrase/recombinase, N-terminal Spica_1680 IPR011010 DNA breaking-rejoining enzyme, catalytic core Spica_1680 IPR013762 Integrase-like, catalytic domain superfamily Spica_1680 IPR002104 Integrase, catalytic domain Spica_1681 IPR020805 Cell division protein FtsZ, conserved site Spica_1681 IPR000158 Cell division protein FtsZ Spica_1681 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Spica_1681 IPR024757 Cell division protein FtsZ, C-terminal Spica_1681 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Spica_1681 IPR003008 Tubulin/FtsZ, GTPase domain Spica_1681 IPR008280 Tubulin/FtsZ, C-terminal Spica_1681 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Spica_1682 IPR020823 Cell division protein FtsA Spica_1682 IPR003494 SHS2 domain inserted in FtsA Spica_1684 IPR013437 Probable peptidoglycan glycosyltransferase FtsW Spica_1684 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA Spica_1684 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site Spica_1685 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site Spica_1685 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase Spica_1685 IPR000715 Glycosyl transferase, family 4 Spica_1686 IPR013221 Mur ligase, central Spica_1686 IPR000713 Mur ligase, N-terminal catalytic domain Spica_1686 IPR035911 MurE/MurF, N-terminal Spica_1686 IPR036565 Mur-like, catalytic domain superfamily Spica_1686 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase Spica_1686 IPR004101 Mur ligase, C-terminal Spica_1686 IPR036615 Mur ligase, C-terminal domain superfamily Spica_1688 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_1688 IPR002903 Ribosomal RNA small subunit methyltransferase H Spica_1688 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily Spica_1689 IPR007159 SpoVT-AbrB domain Spica_1689 IPR038619 MraZ superfamily Spica_1689 IPR035642 MraZ, N-terminal Spica_1689 IPR020603 MraZ domain Spica_1689 IPR035644 MraZ, C-terminal Spica_1689 IPR003444 Transcriptional regulator MraZ Spica_1689 IPR037914 SpoVT-AbrB domain superfamily Spica_1695 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 Spica_1695 IPR013785 Aldolase-type TIM barrel Spica_1695 IPR000771 Fructose-bisphosphate aldolase, class-II Spica_1697 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily Spica_1697 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily Spica_1697 IPR019813 Translation initiation factor 3, conserved site Spica_1697 IPR001288 Translation initiation factor 3 Spica_1697 IPR019815 Translation initiation factor 3, C-terminal Spica_1697 IPR019814 Translation initiation factor 3, N-terminal Spica_1698 IPR037229 Ribosomal protein L35 superfamily Spica_1698 IPR001706 Ribosomal protein L35, non-mitochondrial Spica_1698 IPR018265 Ribosomal protein L35, conserved site Spica_1698 IPR021137 Ribosomal protein L35 Spica_1699 IPR005813 Ribosomal protein L20 Spica_1699 IPR035566 Ribosomal protein L20, C-terminal Spica_1701 IPR007838 Cell division protein ZapA-like Spica_1701 IPR036192 Cell division protein ZapA-like superfamily Spica_1702 IPR001250 Mannose-6-phosphate isomerase, type I Spica_1702 IPR016305 Mannose-6-phosphate isomerase Spica_1702 IPR018050 Phosphomannose isomerase, type I, conserved site Spica_1702 IPR014710 RmlC-like jelly roll fold Spica_1702 IPR011051 RmlC-like cupin domain superfamily Spica_1703 IPR003791 Protein of unknown function UPF0178 Spica_1704 IPR003607 HD/PDEase domain Spica_1704 IPR037522 HD-GYP domain Spica_1704 IPR001789 Signal transduction response regulator, receiver domain Spica_1704 IPR011006 CheY-like superfamily Spica_1704 IPR021800 Domain of unknown function DUF3369 Spica_1705 IPR023059 Foldase protein PrsA Spica_1705 IPR000297 Peptidyl-prolyl cis-trans isomerase, PpiC-type Spica_1705 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Spica_1705 IPR027304 Trigger factor/SurA domain superfamily Spica_1705 IPR037041 Trigger factor, C-terminal domain superfamily Spica_1705 IPR008880 Trigger factor, C-terminal Spica_1707 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Spica_1707 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I Spica_1707 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site Spica_1707 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily Spica_1707 IPR023753 FAD/NAD(P)-binding domain Spica_1707 IPR006258 Dihydrolipoamide dehydrogenase Spica_1707 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1708 IPR011053 Single hybrid motif Spica_1708 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Spica_1708 IPR036625 E3-binding domain superfamily Spica_1708 IPR004167 Peripheral subunit-binding domain Spica_1708 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Spica_1708 IPR000089 Biotin/lipoyl attachment Spica_1708 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain Spica_1708 IPR006257 Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex Spica_1709 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II Spica_1709 IPR029061 Thiamin diphosphate-binding fold Spica_1709 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Spica_1709 IPR033248 Transketolase, C-terminal domain Spica_1709 IPR000089 Biotin/lipoyl attachment Spica_1709 IPR027110 Pyruvate dehydrogenase E1 component subunit beta Spica_1709 IPR011053 Single hybrid motif Spica_1709 IPR005475 Transketolase-like, pyrimidine-binding domain Spica_1710 IPR029061 Thiamin diphosphate-binding fold Spica_1710 IPR017597 Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y Spica_1710 IPR001017 Dehydrogenase, E1 component Spica_1712 IPR003593 AAA+ ATPase domain Spica_1712 IPR003439 ABC transporter-like Spica_1712 IPR017871 ABC transporter, conserved site Spica_1712 IPR015850 ABC transporter, phosphate import, PstB Spica_1712 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1712 IPR005670 Phosphate transport system permease protein 1 Spica_1713 IPR005672 Phosphate transport system permease protein PstA Spica_1713 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_1713 IPR035906 MetI-like superfamily Spica_1714 IPR035906 MetI-like superfamily Spica_1714 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_1714 IPR011864 Phosphate ABC transporter, permease protein PstC Spica_1715 IPR024370 PBP domain Spica_1715 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS Spica_1718 IPR039606 Phytol/farnesol kinase Spica_1720 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1720 IPR002937 Amine oxidase Spica_1720 IPR014105 Carotenoid/retinoid oxidoreductase Spica_1722 IPR017927 FAD-binding domain, ferredoxin reductase-type Spica_1722 IPR012675 Beta-grasp domain superfamily Spica_1722 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain Spica_1722 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Spica_1722 IPR010205 Na(+)-translocating NADH-quinone reductase subunit F Spica_1722 IPR036010 2Fe-2S ferredoxin-like superfamily Spica_1722 IPR008333 Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain Spica_1722 IPR001433 Oxidoreductase FAD/NAD(P)-binding Spica_1722 IPR017938 Riboflavin synthase-like beta-barrel Spica_1723 IPR010967 Na(+)-translocating NADH-quinone reductase subunit E Spica_1723 IPR003667 NqrDE/RnfAE Spica_1724 IPR003667 NqrDE/RnfAE Spica_1724 IPR011292 Na(+)-translocating NADH-quinone reductase subunit D Spica_1725 IPR007329 FMN-binding Spica_1725 IPR010209 Ion-translocating oxidoreductase complex, subunit RnfG/RsxG Spica_1726 IPR010966 Na(+)-translocating NADH-quinone reductase subunit B Spica_1726 IPR004338 Ion-translocating oxidoreductase NqrB/RnfD Spica_1727 IPR024898 Octanoyltransferase LipM Spica_1727 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain Spica_1729 IPR006638 Elp3/MiaB/NifB Spica_1729 IPR003698 Lipoyl synthase Spica_1729 IPR013785 Aldolase-type TIM barrel Spica_1729 IPR007197 Radical SAM Spica_1729 IPR031691 Lipoyl synthase, N-terminal Spica_1730 IPR004107 Integrase, SAM-like, N-terminal Spica_1730 IPR013762 Integrase-like, catalytic domain superfamily Spica_1730 IPR011946 Integrase, integron-type Spica_1730 IPR002104 Integrase, catalytic domain Spica_1730 IPR011010 DNA breaking-rejoining enzyme, catalytic core Spica_1730 IPR010998 Integrase/recombinase, N-terminal Spica_1731 IPR011335 Restriction endonuclease type II-like Spica_1731 IPR025745 Restriction system protein Mrr-like N-terminal domain Spica_1731 IPR007560 Restriction endonuclease type IV, Mrr Spica_1753 IPR025745 Restriction system protein Mrr-like N-terminal domain Spica_1753 IPR011335 Restriction endonuclease type II-like Spica_1753 IPR007560 Restriction endonuclease type IV, Mrr Spica_1758 IPR011335 Restriction endonuclease type II-like Spica_1758 IPR025745 Restriction system protein Mrr-like N-terminal domain Spica_1758 IPR007560 Restriction endonuclease type IV, Mrr Spica_1782 IPR013078 Histidine phosphatase superfamily, clade-1 Spica_1782 IPR029033 Histidine phosphatase superfamily Spica_1782 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site Spica_1795 IPR001207 Transposase, mutator type Spica_1796 IPR001478 PDZ domain Spica_1796 IPR001940 Peptidase S1C Spica_1796 IPR041489 PDZ domain 6 Spica_1796 IPR036034 PDZ superfamily Spica_1796 IPR011782 Peptidase S1C, Do Spica_1796 IPR009003 Peptidase S1, PA clan Spica_1803 IPR003395 RecF/RecN/SMC, N-terminal Spica_1803 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1803 IPR004604 DNA recombination/repair protein RecN Spica_1804 IPR002504 NAD kinase Spica_1804 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal Spica_1804 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal Spica_1804 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily Spica_1805 IPR015424 Pyridoxal phosphate-dependent transferase Spica_1805 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_1805 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_1805 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase Spica_1805 IPR022850 UDP-4-amino-4-deoxy-L-arabinose-oxoglutarate aminotransferase, ArnB Spica_1806 IPR002545 CheW-like domain Spica_1806 IPR036061 CheW-like domain superfamily Spica_1806 IPR039315 Chemotaxis protein CheW Spica_1809 IPR036034 PDZ superfamily Spica_1809 IPR009003 Peptidase S1, PA clan Spica_1809 IPR001478 PDZ domain Spica_1809 IPR001940 Peptidase S1C Spica_1809 IPR011782 Peptidase S1C, Do Spica_1810 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 Spica_1810 IPR001714 Peptidase M24, methionine aminopeptidase Spica_1810 IPR036005 Creatinase/aminopeptidase-like Spica_1810 IPR000994 Peptidase M24 Spica_1811 IPR036869 Chaperone J-domain superfamily Spica_1811 IPR008971 HSP40/DnaJ peptide-binding Spica_1811 IPR001305 Heat shock protein DnaJ, cysteine-rich domain Spica_1811 IPR001623 DnaJ domain Spica_1811 IPR018253 DnaJ domain, conserved site Spica_1811 IPR012724 Chaperone DnaJ Spica_1811 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily Spica_1811 IPR002939 Chaperone DnaJ, C-terminal Spica_1814 IPR002699 ATPase, V1 complex, subunit D Spica_1815 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain Spica_1815 IPR022879 V-type ATP synthase regulatory subunit B/beta Spica_1815 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain Spica_1815 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1816 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal Spica_1816 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension Spica_1816 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1816 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain Spica_1816 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily Spica_1816 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain Spica_1816 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily Spica_1816 IPR022878 V-type ATP synthase catalytic alpha chain Spica_1820 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family Spica_1823 IPR002178 PTS EIIA type-2 domain Spica_1823 IPR016152 Phosphotransferase/anion transporter Spica_1823 IPR006320 Phosphotransferase system, IIA-like nitrogen-regulatory protein PtsN Spica_1824 IPR004692 Preprotein translocase SecG subunit Spica_1825 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic Spica_1825 IPR000652 Triosephosphate isomerase Spica_1825 IPR013785 Aldolase-type TIM barrel Spica_1825 IPR035990 Triosephosphate isomerase superfamily Spica_1825 IPR020861 Triosephosphate isomerase, active site Spica_1826 IPR001576 Phosphoglycerate kinase Spica_1826 IPR015824 Phosphoglycerate kinase, N-terminal Spica_1826 IPR036043 Phosphoglycerate kinase superfamily Spica_1827 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site Spica_1827 IPR036291 NAD(P)-binding domain superfamily Spica_1827 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain Spica_1827 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I Spica_1827 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain Spica_1827 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family Spica_1829 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm Spica_1829 IPR002303 Valine-tRNA ligase Spica_1829 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain Spica_1829 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily Spica_1829 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding Spica_1829 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site Spica_1829 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1829 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm Spica_1829 IPR002300 Aminoacyl-tRNA synthetase, class Ia Spica_1829 IPR033705 Valyl tRNA synthetase, anticodon-binding domain Spica_1829 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding Spica_1830 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Spica_1831 IPR005665 Protein-export membrane protein SecF, bacterial Spica_1831 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spica_1831 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial Spica_1832 IPR022645 Protein-export membrane protein SecD/SecF, bacterial Spica_1832 IPR005791 Protein translocase subunit SecD Spica_1832 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial Spica_1833 IPR003849 Preprotein translocase YajC Spica_1835 IPR024935 Rubredoxin domain Spica_1835 IPR024934 Rubredoxin-like domain Spica_1835 IPR018527 Rubredoxin, iron-binding site Spica_1835 IPR024922 Rubredoxin Spica_1836 IPR004462 Desulforodoxin domain Spica_1836 IPR004793 Desulfoferrodoxin Spica_1836 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily Spica_1836 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain Spica_1836 IPR038094 Desulforodoxin domain superfamily Spica_1837 IPR003251 Rubrerythrin Spica_1837 IPR024934 Rubredoxin-like domain Spica_1837 IPR009078 Ferritin-like superfamily Spica_1837 IPR009040 Ferritin-like diiron domain Spica_1837 IPR012347 Ferritin-like Spica_1844 IPR019489 Clp ATPase, C-terminal Spica_1844 IPR041546 ClpA/ClpB, AAA lid domain Spica_1844 IPR028299 ClpA/B, conserved site 2 Spica_1844 IPR018368 ClpA/B, conserved site 1 Spica_1844 IPR001270 ClpA/B family Spica_1844 IPR004176 Clp, N-terminal Spica_1844 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1844 IPR036628 Clp, N-terminal domain superfamily Spica_1844 IPR017730 Chaperonin ClpB Spica_1844 IPR003959 ATPase, AAA-type, core Spica_1844 IPR003593 AAA+ ATPase domain Spica_1845 IPR036907 5'-Nucleotidase, C-terminal domain superfamily Spica_1845 IPR041827 CpdB, N-terminal metallophosphatase domain Spica_1845 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type Spica_1845 IPR006179 5'-Nucleotidase/apyrase Spica_1845 IPR006146 5'-Nucleotidase, conserved site Spica_1845 IPR029052 Metallo-dependent phosphatase-like Spica_1845 IPR019931 LPXTG cell wall anchor domain Spica_1845 IPR008334 5'-Nucleotidase, C-terminal Spica_1847 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1847 IPR025777 GMP synthetase ATP pyrophosphatase domain Spica_1847 IPR001674 GMP synthase, C-terminal Spica_1847 IPR022955 GMP synthase Spica_1847 IPR029062 Class I glutamine amidotransferase-like Spica_1847 IPR017926 Glutamine amidotransferase Spica_1847 IPR022310 NAD/GMP synthase Spica_1847 IPR004739 GMP synthase, glutamine amidotransferase Spica_1848 IPR042109 Adenylosuccinate synthetase, domain 1 Spica_1848 IPR033128 Adenylosuccinate synthase, active site Spica_1848 IPR018220 Adenylosuccinate synthase, GTP-binding site Spica_1848 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1848 IPR001114 Adenylosuccinate synthetase Spica_1848 IPR042111 Adenylosuccinate synthetase, domain 3 Spica_1848 IPR042110 Adenylosuccinate synthetase, domain 2 Spica_1849 IPR001093 IMP dehydrogenase/GMP reductase Spica_1849 IPR015875 IMP dehydrogenase / GMP reductase, conserved site Spica_1849 IPR005990 Inosine-5'-monophosphate dehydrogenase Spica_1849 IPR000644 CBS domain Spica_1849 IPR013785 Aldolase-type TIM barrel Spica_1850 IPR020557 Fumarate lyase, conserved site Spica_1850 IPR004769 Adenylosuccinate lyase Spica_1850 IPR008948 L-Aspartase-like Spica_1850 IPR022761 Fumarate lyase, N-terminal Spica_1850 IPR000362 Fumarate lyase family Spica_1850 IPR024083 Fumarase/histidase, N-terminal Spica_1850 IPR019468 Adenylosuccinate lyase C-terminal Spica_1852 IPR023214 HAD superfamily Spica_1852 IPR036412 HAD-like superfamily Spica_1852 IPR006379 HAD-superfamily hydrolase, subfamily IIB Spica_1852 IPR000150 Cof family Spica_1858 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 Spica_1858 IPR023753 FAD/NAD(P)-binding domain Spica_1858 IPR009051 Alpha-helical ferredoxin Spica_1858 IPR028261 Dihydroprymidine dehydrogenase domain II Spica_1858 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1859 IPR017932 Glutamine amidotransferase type 2 domain Spica_1859 IPR029055 Nucleophile aminohydrolases, N-terminal Spica_1859 IPR002932 Glutamate synthase domain Spica_1859 IPR013785 Aldolase-type TIM barrel Spica_1859 IPR002489 Glutamate synthase, alpha subunit, C-terminal Spica_1859 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily Spica_1859 IPR006982 Glutamate synthase, central-N Spica_1861 IPR033479 Double Cache domain 1 Spica_1861 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_1861 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1861 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1861 IPR003660 HAMP domain Spica_1861 IPR005467 Histidine kinase domain Spica_1861 IPR010559 Signal transduction histidine kinase, internal region Spica_1862 IPR011006 CheY-like superfamily Spica_1862 IPR009057 Homeobox-like domain superfamily Spica_1862 IPR018060 DNA binding HTH domain, AraC-type Spica_1862 IPR001789 Signal transduction response regulator, receiver domain Spica_1863 IPR013456 D-xylose ABC transporter, substrate-binding protein Spica_1863 IPR025997 Periplasmic binding protein Spica_1863 IPR028082 Periplasmic binding protein-like I Spica_1864 IPR028082 Periplasmic binding protein-like I Spica_1864 IPR025997 Periplasmic binding protein Spica_1865 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1865 IPR003593 AAA+ ATPase domain Spica_1865 IPR015862 ABC transporter, galactose import, MglA Spica_1865 IPR017871 ABC transporter, conserved site Spica_1865 IPR003439 ABC transporter-like Spica_1866 IPR030158 Galactoside transport system permease protein MglC Spica_1866 IPR001851 ABC transporter, permease Spica_1873 IPR015946 K homology domain-like, alpha/beta Spica_1873 IPR006073 GTP binding domain Spica_1873 IPR016484 GTP-binding protein EngA Spica_1873 IPR031166 EngA-type guanine nucleotide-binding (G) domain Spica_1873 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1873 IPR032859 GTPase Der, C-terminal KH-domain-like Spica_1873 IPR005225 Small GTP-binding protein domain Spica_1874 IPR008948 L-Aspartase-like Spica_1874 IPR022761 Fumarate lyase, N-terminal Spica_1874 IPR000362 Fumarate lyase family Spica_1874 IPR004708 Aspartate ammonia-lyase Spica_1874 IPR024083 Fumarase/histidase, N-terminal Spica_1874 IPR018951 Fumarase C, C-terminal Spica_1874 IPR020557 Fumarate lyase, conserved site Spica_1875 IPR013785 Aldolase-type TIM barrel Spica_1875 IPR010722 Biotin and thiamin synthesis-associated domain Spica_1875 IPR006638 Elp3/MiaB/NifB Spica_1875 IPR007197 Radical SAM Spica_1875 IPR034422 HydE/PylB-like Spica_1875 IPR024021 [FeFe]-hydrogenase maturation HydE, radical SAM Spica_1876 IPR007197 Radical SAM Spica_1876 IPR012726 Thiazole biosynthesis ThiH Spica_1876 IPR034428 ThiH/NocL/HydG-like Spica_1876 IPR010722 Biotin and thiamin synthesis-associated domain Spica_1876 IPR013785 Aldolase-type TIM barrel Spica_1882 IPR004090 Chemotaxis methyl-accepting receptor Spica_1882 IPR003660 HAMP domain Spica_1882 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_1882 IPR033463 Single cache domain 3 Spica_1882 IPR029151 Periplasmic sensor-like domain superfamily Spica_1884 IPR013014 Phosphotransferase system, EIIC component, type 2 Spica_1884 IPR002178 PTS EIIA type-2 domain Spica_1884 IPR016152 Phosphotransferase/anion transporter Spica_1884 IPR004715 Phosphotransferase system, IIA component fructose subfamily Spica_1884 IPR003501 Phosphotransferase system, EIIB component, type 2/3 Spica_1884 IPR003353 Phosphotransferase system, fructose-specific IIB subunit Spica_1884 IPR006327 Phosphotransferase system, fructose IIC component Spica_1884 IPR036095 PTS system IIB component-like superfamily Spica_1884 IPR013011 Phosphotransferase system, EIIB component, type 2 Spica_1885 IPR008141 Alanine dehydrogenase Spica_1885 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain Spica_1885 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal Spica_1885 IPR036291 NAD(P)-binding domain superfamily Spica_1885 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 Spica_1885 IPR008142 Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 Spica_1887 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG Spica_1887 IPR011701 Major facilitator superfamily Spica_1887 IPR020846 Major facilitator superfamily domain Spica_1887 IPR005828 Major facilitator, sugar transporter-like Spica_1887 IPR036259 MFS transporter superfamily Spica_1889 IPR004593 Nuclease SbcCD subunit D Spica_1889 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type Spica_1889 IPR029052 Metallo-dependent phosphatase-like Spica_1889 IPR041796 Mre11 nuclease, N-terminal metallophosphatase domain Spica_1889 IPR026843 Nuclease SbcCD subunit D, C-terminal domain Spica_1890 IPR038729 Rad50/SbcC-type AAA domain Spica_1890 IPR004592 Nuclease SbcC, gammaproteobacteria type Spica_1890 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1891 IPR035919 EAL domain superfamily Spica_1891 IPR001633 EAL domain Spica_1891 IPR000160 GGDEF domain Spica_1891 IPR005330 MHYT domain Spica_1891 IPR029787 Nucleotide cyclase Spica_1892 IPR036380 Isochorismatase-like superfamily Spica_1892 IPR000868 Isochorismatase-like Spica_1893 IPR007229 Nicotinate phosphoribosyltransferase family Spica_1893 IPR006405 Nicotinate phosphoribosyltransferase pncB-type Spica_1893 IPR040727 Nicotinate phosphoribosyltransferase, N-terminal domain Spica_1893 IPR041619 Nicotinate phosphoribosyltransferase C-terminal domain Spica_1893 IPR041525 Nicotinate/nicotinamide phosphoribosyltransferase Spica_1893 IPR013785 Aldolase-type TIM barrel Spica_1893 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal Spica_1894 IPR030395 Glycerophosphodiester phosphodiesterase domain Spica_1894 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily Spica_1895 IPR006059 Bacterial extracellular solute-binding protein Spica_1895 IPR006061 Solute-binding family 1, conserved site Spica_1896 IPR035906 MetI-like superfamily Spica_1896 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_1897 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_1897 IPR035906 MetI-like superfamily Spica_1897 IPR030165 sn-Glycerol-3-phosphate transport system permease protein UgpE Spica_1898 IPR004175 RNA 2',3'-cyclic phosphodiesterase Spica_1898 IPR014051 Phosphoesterase, HXTX Spica_1898 IPR009097 Cyclic phosphodiesterase Spica_1899 IPR001320 Ionotropic glutamate receptor Spica_1899 IPR018313 Solute-binding protein family 3, conserved site Spica_1899 IPR005768 Specific amino acids and opine-binding periplasmic protein, ABC transporter Spica_1899 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spica_1900 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_1900 IPR035906 MetI-like superfamily Spica_1900 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain Spica_1901 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Spica_1901 IPR012089 tRNA-cytidine(32) 2-sulfurtransferase Spica_1901 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type Spica_1901 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1907 IPR035906 MetI-like superfamily Spica_1907 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_1908 IPR035906 MetI-like superfamily Spica_1908 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_1909 IPR006059 Bacterial extracellular solute-binding protein Spica_1910 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily Spica_1910 IPR036390 Winged helix DNA-binding domain superfamily Spica_1910 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1910 IPR011663 UbiC transcription regulator-associated Spica_1910 IPR000524 Transcription regulator HTH, GntR Spica_1910 IPR012770 Trehalose operon transcriptional repressor Spica_1911 IPR036852 Peptidase S8/S53 domain superfamily Spica_1911 IPR006315 Outer membrane autotransporter barrel Spica_1911 IPR013425 Autotransporter-associated beta strand repeat Spica_1911 IPR036709 Autotransporter beta-domain superfamily Spica_1911 IPR005546 Autotransporter beta-domain Spica_1911 IPR023828 Peptidase S8, subtilisin, Ser-active site Spica_1911 IPR000209 Peptidase S8/S53 domain Spica_1911 IPR015500 Peptidase S8, subtilisin-related Spica_1911 IPR034061 Autotransporter serine protease peptidase domain Spica_1911 IPR022398 Peptidase S8, subtilisin, His-active site Spica_1911 IPR011050 Pectin lyase fold/virulence factor Spica_1913 IPR013783 Immunoglobulin-like fold Spica_1913 IPR004199 Beta galactosidase small chain/ domain 5 Spica_1913 IPR017853 Glycoside hydrolase superfamily Spica_1913 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich Spica_1913 IPR032312 Beta-galactosidase, domain 4 Spica_1913 IPR036156 Beta-Galactosidase/glucuronidase domain superfamily Spica_1913 IPR011013 Galactose mutarotase-like domain superfamily Spica_1913 IPR023230 Glycoside hydrolase, family 2, conserved site Spica_1913 IPR008979 Galactose-binding-like domain superfamily Spica_1913 IPR014718 Glycoside hydrolase-type carbohydrate-binding Spica_1913 IPR006101 Glycoside hydrolase, family 2 Spica_1913 IPR023232 Glycoside hydrolase, family 2, active site Spica_1913 IPR006103 Glycoside hydrolase family 2, catalytic domain Spica_1913 IPR006104 Glycosyl hydrolases family 2, sugar binding domain Spica_1913 IPR023933 Glycoside hydrolase, family 2, beta-galactosidase Spica_1914 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1914 IPR033532 Arabinose metabolism transcriptional repressor, ligand-binding domain Spica_1914 IPR036390 Winged helix DNA-binding domain superfamily Spica_1914 IPR000524 Transcription regulator HTH, GntR Spica_1914 IPR028082 Periplasmic binding protein-like I Spica_1917 IPR026591 Sirtuin, catalytic core small domain superfamily Spica_1917 IPR028628 Sirtuin, class U Spica_1917 IPR026590 Sirtuin family, catalytic core domain Spica_1917 IPR029035 DHS-like NAD/FAD-binding domain superfamily Spica_1917 IPR003000 Sirtuin family Spica_1923 IPR021127 CRISPR-associated endonuclease Cas2 Spica_1923 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 Spica_1924 IPR019856 CRISPR-associated protein Cas1, DVULG subtype Spica_1924 IPR042211 CRISPR-associated endonuclease Cas1, N-terminal domain Spica_1924 IPR042206 CRISPR-associated endonuclease Cas1, C-terminal domain Spica_1924 IPR002729 CRISPR-associated protein Cas1 Spica_1928 IPR010155 CRISPR pre-crRNA endoribonuclease Cas5d Spica_1928 IPR013422 CRISPR-associated protein Cas5, N-terminal Spica_1928 IPR021124 CRISPR-associated protein, Cas5 Spica_1931 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site Spica_1931 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 Spica_1931 IPR002305 Aminoacyl-tRNA synthetase, class Ic Spica_1931 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_1931 IPR002942 RNA-binding S4 domain Spica_1931 IPR002307 Tyrosine-tRNA ligase Spica_1931 IPR024088 Tyrosine-tRNA ligase, bacterial-type Spica_1931 IPR036986 RNA-binding S4 domain superfamily Spica_1933 IPR029018 Beta-hexosaminidase-like, domain 2 Spica_1933 IPR025705 Beta-hexosaminidase Spica_1933 IPR015883 Glycoside hydrolase family 20, catalytic domain Spica_1933 IPR017853 Glycoside hydrolase superfamily Spica_1933 IPR011658 PA14 domain Spica_1933 IPR037524 PA14/GLEYA domain Spica_1933 IPR015882 Beta-hexosaminidase, bacterial type, N-terminal Spica_1936 IPR002579 Peptide methionine sulphoxide reductase MrsB Spica_1936 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily Spica_1936 IPR002569 Peptide methionine sulphoxide reductase MsrA Spica_1936 IPR028427 Peptide methionine sulfoxide reductase Spica_1936 IPR011057 Mss4-like superfamily Spica_1937 IPR001650 Helicase, C-terminal Spica_1937 IPR036876 UVR domain superfamily Spica_1937 IPR024759 UvrB, YAD/RRR-motif-containing domain Spica_1937 IPR041471 UvrB, interaction domain Spica_1937 IPR004807 UvrABC system, subunit B Spica_1937 IPR001943 UVR domain Spica_1937 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1937 IPR006935 Helicase/UvrB, N-terminal Spica_1937 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1938 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1938 IPR005467 Histidine kinase domain Spica_1938 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_1938 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1938 IPR003660 HAMP domain Spica_1938 IPR006290 Heavy metal sensor kinase Spica_1938 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_1940 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_1940 IPR020605 Octanoyltransferase, conserved site Spica_1940 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain Spica_1940 IPR001279 Metallo-beta-lactamase Spica_1940 IPR000544 Octanoyltransferase Spica_1941 IPR026569 Ribosomal protein L28/L24 Spica_1941 IPR034704 L28p-like Spica_1941 IPR001383 Ribosomal protein L28 Spica_1941 IPR037147 Ribosomal protein L28/L24 superfamily Spica_1944 IPR015424 Pyridoxal phosphate-dependent transferase Spica_1944 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_1944 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme Spica_1944 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_1944 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase Spica_1945 IPR003660 HAMP domain Spica_1945 IPR004090 Chemotaxis methyl-accepting receptor Spica_1945 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_1945 IPR033479 Double Cache domain 1 Spica_1945 IPR000727 Target SNARE coiled-coil homology domain Spica_1945 IPR029151 Periplasmic sensor-like domain superfamily Spica_1947 IPR008269 Peptidase S16, Lon proteolytic domain Spica_1947 IPR003593 AAA+ ATPase domain Spica_1947 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_1947 IPR003959 ATPase, AAA-type, core Spica_1947 IPR004815 Lon protease, bacterial/eukaryotic-type Spica_1947 IPR027543 Lon protease, bacterial Spica_1947 IPR027065 Lon protease Spica_1947 IPR008268 Peptidase S16, active site Spica_1947 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1947 IPR015947 PUA-like superfamily Spica_1947 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_1947 IPR003111 Lon, substrate-binding domain Spica_1948 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_1948 IPR003594 Histidine kinase/HSP90-like ATPase Spica_1948 IPR038424 Signal transduction histidine kinase, N-terminal domain superfamily Spica_1948 IPR035965 PAS domain superfamily Spica_1948 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_1948 IPR022066 Signal transduction histidine kinase, N-terminal Spica_1948 IPR005467 Histidine kinase domain Spica_1954 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial Spica_1954 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1954 IPR004589 DNA helicase, ATP-dependent, RecQ type Spica_1954 IPR011545 DEAD/DEAH box helicase domain Spica_1954 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1954 IPR010997 HRDC-like superfamily Spica_1954 IPR018982 RQC domain Spica_1954 IPR002121 HRDC domain Spica_1954 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1954 IPR001650 Helicase, C-terminal Spica_1954 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain Spica_1955 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site Spica_1955 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1955 IPR001650 Helicase, C-terminal Spica_1955 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1955 IPR014014 RNA helicase, DEAD-box type, Q motif Spica_1955 IPR030880 DEAD-box ATP-dependent RNA helicase CshA Spica_1955 IPR011545 DEAD/DEAH box helicase domain Spica_1957 IPR013785 Aldolase-type TIM barrel Spica_1957 IPR005720 Dihydroorotate dehydrogenase domain Spica_1957 IPR001295 Dihydroorotate dehydrogenase, conserved site Spica_1957 IPR005719 Dihydroorotate dehydrogenase, class 2 Spica_1958 IPR032779 Flagellar motor switch protein FliG, middle domain Spica_1958 IPR028263 Flagellar motor switch protein FliG, N-terminal domain Spica_1958 IPR000090 Flagellar motor switch protein FliG Spica_1958 IPR011002 Flagellar motor switch protein FliG, alpha-helical Spica_1958 IPR023087 Flagellar motor switch protein FliG, C-terminal Spica_1959 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like Spica_1959 IPR011765 Peptidase M16, N-terminal Spica_1959 IPR007863 Peptidase M16, C-terminal Spica_1959 IPR013578 Peptidase M16C associated Spica_1961 IPR011545 DEAD/DEAH box helicase domain Spica_1961 IPR001650 Helicase, C-terminal Spica_1961 IPR012340 Nucleic acid-binding, OB-fold Spica_1961 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1961 IPR033454 RecG, wedge domain Spica_1961 IPR004609 ATP-dependent DNA helicase RecG Spica_1961 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_1963 IPR000160 GGDEF domain Spica_1963 IPR029787 Nucleotide cyclase Spica_1963 IPR001789 Signal transduction response regulator, receiver domain Spica_1963 IPR011006 CheY-like superfamily Spica_1964 IPR004013 PHP domain Spica_1964 IPR004805 DNA polymerase III, alpha subunit Spica_1964 IPR041931 Bacterial DNA polymerase III alpha subunit, thumb domain Spica_1964 IPR040982 DNA polymerase III alpha subunit finger domain Spica_1964 IPR029460 DNA polymerase, helix-hairpin-helix motif Spica_1964 IPR003141 Polymerase/histidinol phosphatase, N-terminal Spica_1964 IPR016195 Polymerase/histidinol phosphatase-like Spica_1964 IPR011708 Bacterial DNA polymerase III, alpha subunit, NTPase domain Spica_1965 IPR010982 Lambda repressor-like, DNA-binding domain superfamily Spica_1965 IPR028082 Periplasmic binding protein-like I Spica_1965 IPR023588 Transcription regulator HTH, PurR Spica_1965 IPR000843 LacI-type HTH domain Spica_1966 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_1966 IPR004839 Aminotransferase, class I/classII Spica_1966 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_1966 IPR015424 Pyridoxal phosphate-dependent transferase Spica_1968 IPR001911 Ribosomal protein S21 Spica_1968 IPR038380 Ribosomal protein S21 superfamily Spica_1968 IPR018278 Ribosomal protein S21, conserved site Spica_1969 IPR011055 Duplicated hybrid motif Spica_1969 IPR007340 Opacity-associated protein A Spica_1969 IPR016047 Peptidase M23 Spica_1970 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal Spica_1970 IPR004610 Bacterial RecJ exonuclease Spica_1970 IPR003156 DHHA1 domain Spica_1970 IPR041122 RecJ, OB domain Spica_1970 IPR038763 DHH phosphoesterase superfamily Spica_1970 IPR001667 DDH domain Spica_1971 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic Spica_1971 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase Spica_1971 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site Spica_1971 IPR017459 Glycosyl transferase family 3, N-terminal domain Spica_1971 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Spica_1971 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily Spica_1971 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Spica_1971 IPR000312 Glycosyl transferase, family 3 Spica_1971 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal Spica_1973 IPR036393 Acetylglutamate kinase-like superfamily Spica_1973 IPR010167 Amino-acid N-acetyltransferase Spica_1973 IPR001048 Aspartate/glutamate/uridylate kinase Spica_1973 IPR000182 GNAT domain Spica_1973 IPR016181 Acyl-CoA N-acyltransferase Spica_1973 IPR033719 N-acetylglutamate synthase, kinase-like domain Spica_1974 IPR000788 Ribonucleotide reductase large subunit, C-terminal Spica_1974 IPR029072 YebC-like Spica_1974 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain Spica_1974 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent Spica_1978 IPR003689 Zinc/iron permease Spica_1979 IPR006259 Adenylate kinase subfamily Spica_1979 IPR000850 Adenylate kinase/UMP-CMP kinase Spica_1979 IPR033690 Adenylate kinase, conserved site Spica_1979 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1979 IPR007862 Adenylate kinase, active site lid domain Spica_1980 IPR018517 tRNA-dihydrouridine synthase, conserved site Spica_1980 IPR013785 Aldolase-type TIM barrel Spica_1980 IPR001269 tRNA-dihydrouridine synthase Spica_1980 IPR035587 DUS-like, FMN-binding domain Spica_1980 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal Spica_1981 IPR037171 NagB/RpiA transferase-like Spica_1981 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_1981 IPR001034 DeoR-type HTH domain Spica_1981 IPR014036 DeoR C-terminal sensor domain Spica_1981 IPR036390 Winged helix DNA-binding domain superfamily Spica_1981 IPR018356 Transcription regulator, HTH DeoR-type, conserved site Spica_1982 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain Spica_1982 IPR000089 Biotin/lipoyl attachment Spica_1982 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Spica_1982 IPR036625 E3-binding domain superfamily Spica_1982 IPR011053 Single hybrid motif Spica_1982 IPR004167 Peripheral subunit-binding domain Spica_1983 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Spica_1983 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I Spica_1983 IPR006258 Dihydrolipoamide dehydrogenase Spica_1983 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily Spica_1983 IPR023753 FAD/NAD(P)-binding domain Spica_1983 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_1983 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site Spica_1984 IPR033248 Transketolase, C-terminal domain Spica_1984 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II Spica_1984 IPR029061 Thiamin diphosphate-binding fold Spica_1984 IPR005475 Transketolase-like, pyrimidine-binding domain Spica_1986 IPR036291 NAD(P)-binding domain superfamily Spica_1986 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_1988 IPR013154 Alcohol dehydrogenase, N-terminal Spica_1988 IPR013149 Alcohol dehydrogenase, C-terminal Spica_1988 IPR036291 NAD(P)-binding domain superfamily Spica_1988 IPR011032 GroES-like superfamily Spica_1991 IPR029070 Chitinase insertion domain superfamily Spica_1991 IPR017853 Glycoside hydrolase superfamily Spica_1991 IPR001579 Glycoside hydrolase, chitinase active site Spica_1991 IPR001223 Glycoside hydrolase family 18, catalytic domain Spica_1991 IPR003610 Carbohydrate-binding module family 5/12 Spica_1991 IPR036573 Carbohydrate-binding module superfamily 5/12 Spica_1991 IPR011583 Chitinase II Spica_1993 IPR041682 AAA domain, group 14 Spica_1993 IPR025420 Domain of unknown function DUF4143 Spica_1993 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_1994 IPR004090 Chemotaxis methyl-accepting receptor Spica_1994 IPR004091 Chemotaxis methyl-accepting receptor, methyl-accepting site Spica_1994 IPR003660 HAMP domain Spica_1994 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding Spica_1994 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_1994 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain superfamily Spica_2000 IPR003838 ABC transporter permease protein domain Spica_2000 IPR025857 MacB-like periplasmic core domain Spica_2000 IPR005085 Carbohydrate binding module family 25 Spica_2001 IPR003593 AAA+ ATPase domain Spica_2001 IPR003838 ABC transporter permease protein domain Spica_2001 IPR003439 ABC transporter-like Spica_2001 IPR017871 ABC transporter, conserved site Spica_2001 IPR017911 ABC transporter, macrolide export, ATP-binding domain Spica_2001 IPR025857 MacB-like periplasmic core domain Spica_2001 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2002 IPR003593 AAA+ ATPase domain Spica_2002 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2002 IPR017871 ABC transporter, conserved site Spica_2002 IPR003439 ABC transporter-like Spica_2004 IPR000014 PAS domain Spica_2004 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_2004 IPR031967 PhoR, single Cache-like domain Spica_2004 IPR013767 PAS fold Spica_2004 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_2004 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_2004 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2004 IPR035965 PAS domain superfamily Spica_2004 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2004 IPR005467 Histidine kinase domain Spica_2005 IPR016032 Signal transduction response regulator, C-terminal effector Spica_2005 IPR039420 Transcriptional regulatory protein WalR-like Spica_2005 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2005 IPR001867 OmpR/PhoB-type DNA-binding domain Spica_2005 IPR011006 CheY-like superfamily Spica_2005 IPR001789 Signal transduction response regulator, receiver domain Spica_2007 IPR001851 ABC transporter, permease Spica_2008 IPR003593 AAA+ ATPase domain Spica_2008 IPR003439 ABC transporter-like Spica_2008 IPR017871 ABC transporter, conserved site Spica_2008 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2009 IPR025997 Periplasmic binding protein Spica_2009 IPR028082 Periplasmic binding protein-like I Spica_2010 IPR028082 Periplasmic binding protein-like I Spica_2010 IPR025997 Periplasmic binding protein Spica_2010 IPR013456 D-xylose ABC transporter, substrate-binding protein Spica_2011 IPR011006 CheY-like superfamily Spica_2011 IPR016032 Signal transduction response regulator, C-terminal effector Spica_2011 IPR001789 Signal transduction response regulator, receiver domain Spica_2011 IPR000792 Transcription regulator LuxR, C-terminal Spica_2012 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2012 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2012 IPR005467 Histidine kinase domain Spica_2012 IPR003660 HAMP domain Spica_2012 IPR010559 Signal transduction histidine kinase, internal region Spica_2012 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_2012 IPR033479 Double Cache domain 1 Spica_2014 IPR016181 Acyl-CoA N-acyltransferase Spica_2014 IPR004616 Leucyl/phenylalanyl-tRNA-protein transferase Spica_2014 IPR042203 Leucyl/phenylalanyl-tRNA-protein transferase, C-terminal Spica_2015 IPR018368 ClpA/B, conserved site 1 Spica_2015 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2015 IPR041546 ClpA/ClpB, AAA lid domain Spica_2015 IPR028299 ClpA/B, conserved site 2 Spica_2015 IPR001270 ClpA/B family Spica_2015 IPR013461 ATP-dependent Clp protease ATP-binding subunit ClpA Spica_2015 IPR003593 AAA+ ATPase domain Spica_2015 IPR003959 ATPase, AAA-type, core Spica_2015 IPR004176 Clp, N-terminal Spica_2015 IPR019489 Clp ATPase, C-terminal Spica_2015 IPR036628 Clp, N-terminal domain superfamily Spica_2016 IPR022935 ATP-dependent Clp protease adaptor protein ClpS Spica_2016 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like Spica_2016 IPR003769 Adaptor protein ClpS, core Spica_2019 IPR005135 Endonuclease/exonuclease/phosphatase Spica_2019 IPR036691 Endonuclease/exonuclease/phosphatase superfamily Spica_2019 IPR020848 AP endonuclease 1, conserved site Spica_2019 IPR020847 AP endonuclease 1, binding site Spica_2019 IPR004808 AP endonuclease 1 Spica_2022 IPR010720 Alpha-L-arabinofuranosidase, C-terminal Spica_2022 IPR013780 Glycosyl hydrolase, all-beta Spica_2022 IPR017853 Glycoside hydrolase superfamily Spica_2023 IPR001036 Acriflavin resistance protein Spica_2023 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains Spica_2024 IPR006143 RND efflux pump, membrane fusion protein Spica_2024 IPR030190 Macrolide export protein MacA Spica_2024 IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain Spica_2026 IPR012340 Nucleic acid-binding, OB-fold Spica_2026 IPR003029 S1 domain Spica_2026 IPR022967 RNA-binding domain, S1 Spica_2026 IPR000110 Ribosomal protein S1 Spica_2028 IPR003018 GAF domain Spica_2028 IPR000614 Free Met sulfoxide reductase conserved site Spica_2028 IPR029016 GAF-like domain superfamily Spica_2029 IPR002549 Transmembrane protein TqsA-like Spica_2031 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2031 IPR035906 MetI-like superfamily Spica_2032 IPR025966 Oligopeptide transport permease C-like, N-terminal domain Spica_2032 IPR035906 MetI-like superfamily Spica_2032 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2033 IPR003593 AAA+ ATPase domain Spica_2033 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2033 IPR003439 ABC transporter-like Spica_2033 IPR017871 ABC transporter, conserved site Spica_2033 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal Spica_2034 IPR003593 AAA+ ATPase domain Spica_2034 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2034 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal Spica_2034 IPR017871 ABC transporter, conserved site Spica_2034 IPR003439 ABC transporter-like Spica_2035 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 Spica_2035 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal Spica_2035 IPR016039 Thiolase-like Spica_2035 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Spica_2036 IPR001227 Acyl transferase domain superfamily Spica_2036 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase Spica_2036 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding Spica_2036 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type Spica_2036 IPR014043 Acyl transferase Spica_2037 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase Spica_2037 IPR002347 Short-chain dehydrogenase/reductase SDR Spica_2037 IPR020904 Short-chain dehydrogenase/reductase, conserved site Spica_2037 IPR036291 NAD(P)-binding domain superfamily Spica_2038 IPR014031 Beta-ketoacyl synthase, C-terminal Spica_2038 IPR014030 Beta-ketoacyl synthase, N-terminal Spica_2038 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain Spica_2038 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 Spica_2038 IPR016039 Thiolase-like Spica_2038 IPR018201 Beta-ketoacyl synthase, active site Spica_2038 IPR000794 Beta-ketoacyl synthase Spica_2039 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ Spica_2039 IPR029069 HotDog domain superfamily Spica_2039 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ Spica_2040 IPR010758 Trans-2-enoyl-CoA reductase Spica_2040 IPR024910 Trans-2-enoyl-CoA reductase catalytic domain, putative Spica_2040 IPR024906 Enoyl reductase FAD binding domain Spica_2041 IPR001249 Acetyl-CoA biotin carboxyl carrier Spica_2041 IPR011053 Single hybrid motif Spica_2041 IPR000089 Biotin/lipoyl attachment Spica_2041 IPR001882 Biotin-binding site Spica_2042 IPR011761 ATP-grasp fold Spica_2042 IPR016185 Pre-ATP-grasp domain superfamily Spica_2042 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase Spica_2042 IPR013815 ATP-grasp fold, subdomain 1 Spica_2042 IPR005481 Biotin carboxylase-like, N-terminal domain Spica_2042 IPR011764 Biotin carboxylation domain Spica_2042 IPR011054 Rudiment single hybrid motif Spica_2042 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain Spica_2042 IPR005482 Biotin carboxylase, C-terminal Spica_2043 IPR034733 Acetyl-CoA carboxylase Spica_2043 IPR011762 Acetyl-coenzyme A carboxyltransferase, N-terminal Spica_2043 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit Spica_2043 IPR029045 ClpP/crotonase-like domain superfamily Spica_2044 IPR011763 Acetyl-coenzyme A carboxyltransferase, C-terminal Spica_2044 IPR029045 ClpP/crotonase-like domain superfamily Spica_2044 IPR001095 Acetyl-CoA carboxylase, alpha subunit Spica_2046 IPR002524 Cation efflux protein Spica_2046 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Spica_2046 IPR027470 Cation efflux protein, cytoplasmic domain Spica_2046 IPR027469 Cation efflux transmembrane domain superfamily Spica_2046 IPR023783 Cation efflux pump FieF Spica_2048 IPR001347 Sugar isomerase (SIS) Spica_2048 IPR035490 GlmS/FrlB, SIS domain 2 Spica_2048 IPR017932 Glutamine amidotransferase type 2 domain Spica_2048 IPR029055 Nucleophile aminohydrolases, N-terminal Spica_2048 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising Spica_2048 IPR035466 GlmS/AgaS, SIS domain 1 Spica_2050 IPR011344 Single-stranded DNA-binding protein Spica_2050 IPR012340 Nucleic acid-binding, OB-fold Spica_2050 IPR000424 Primosome PriB/single-strand DNA-binding Spica_2052 IPR002771 Multiple antibiotic resistance (MarC)-related Spica_2053 IPR013766 Thioredoxin domain Spica_2053 IPR017937 Thioredoxin, conserved site Spica_2053 IPR036249 Thioredoxin-like superfamily Spica_2053 IPR005746 Thioredoxin Spica_2056 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain Spica_2056 IPR023741 Lipoate-protein ligase A Spica_2056 IPR019491 Lipoate protein ligase, C-terminal Spica_2056 IPR004562 Lipoyltransferase/lipoate-protein ligase Spica_2063 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2063 IPR031322 Shikimate kinase/gluconokinase Spica_2063 IPR000623 Shikimate kinase/Threonine synthase-like 1 Spica_2063 IPR023000 Shikimate kinase, conserved site Spica_2064 IPR001633 EAL domain Spica_2064 IPR013656 PAS fold-4 Spica_2064 IPR035965 PAS domain superfamily Spica_2064 IPR000160 GGDEF domain Spica_2064 IPR000014 PAS domain Spica_2064 IPR029787 Nucleotide cyclase Spica_2064 IPR035919 EAL domain superfamily Spica_2066 IPR035966 Phosphofructokinase superfamily Spica_2066 IPR000023 Phosphofructokinase domain Spica_2066 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type Spica_2066 IPR022953 ATP-dependent 6-phosphofructokinase Spica_2066 IPR012829 Phosphofructokinase, mixed-substrate PFK group III Spica_2068 IPR017853 Glycoside hydrolase superfamily Spica_2068 IPR000322 Glycoside hydrolase family 31 Spica_2068 IPR011013 Galactose mutarotase-like domain superfamily Spica_2068 IPR013780 Glycosyl hydrolase, all-beta Spica_2070 IPR018043 Sodium:galactoside symporter, conserved site Spica_2070 IPR036259 MFS transporter superfamily Spica_2070 IPR039672 Lactose permease-like Spica_2072 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2072 IPR035906 MetI-like superfamily Spica_2076 IPR004654 Glucokinase ROK Spica_2076 IPR000600 ROK family Spica_2077 IPR000594 THIF-type NAD/FAD binding fold Spica_2077 IPR035985 Ubiquitin-activating enzyme Spica_2080 IPR001238 DNA-binding, RecF Spica_2080 IPR018078 DNA-binding, RecF, conserved site Spica_2080 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2080 IPR003395 RecF/RecN/SMC, N-terminal Spica_2080 IPR042174 DNA-binding RecF, domain 2 Spica_2084 IPR023949 RNA polymerase-associated protein RapA Spica_2084 IPR038718 SNF2-like, N-terminal domain superfamily Spica_2084 IPR040765 RapA, N-terminal Tudor like domain 1 Spica_2084 IPR022737 RNA polymerase recycling, bacterial, C-terminal Spica_2084 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2084 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_2084 IPR001650 Helicase, C-terminal Spica_2084 IPR000330 SNF2-related, N-terminal domain Spica_2084 IPR040766 RapA, N-terminal Tudor-like domain 2 Spica_2087 IPR005474 Transketolase, N-terminal Spica_2087 IPR029061 Thiamin diphosphate-binding fold Spica_2088 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II Spica_2088 IPR029061 Thiamin diphosphate-binding fold Spica_2088 IPR033248 Transketolase, C-terminal domain Spica_2088 IPR005475 Transketolase-like, pyrimidine-binding domain Spica_2089 IPR004785 Ribose 5-phosphate isomerase B Spica_2089 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family Spica_2089 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily Spica_2090 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA Spica_2090 IPR018211 Alcohol dehydrogenase, iron-type, conserved site Spica_2090 IPR039697 Iron-type alcohol dehydrogenase-like Spica_2093 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spica_2093 IPR005856 Cysteine synthase Spica_2093 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site Spica_2093 IPR005859 Cysteine synthase CysK Spica_2093 IPR001926 Pyridoxal-phosphate dependent enzyme Spica_2094 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily Spica_2094 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase Spica_2094 IPR033879 Undecaprenyl-diphosphatase Spica_2095 IPR001789 Signal transduction response regulator, receiver domain Spica_2095 IPR037522 HD-GYP domain Spica_2095 IPR003607 HD/PDEase domain Spica_2095 IPR011006 CheY-like superfamily Spica_2096 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type Spica_2096 IPR029044 Nucleotide-diphospho-sugar transferases Spica_2096 IPR005835 Nucleotidyl transferase domain Spica_2098 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 Spica_2098 IPR018948 GTP-binding protein TrmE, N-terminal Spica_2098 IPR031168 TrmE-type guanine nucleotide-binding domain Spica_2098 IPR004520 tRNA modification GTPase MnmE Spica_2098 IPR027368 tRNA modification GTPase MnmE domain 2 Spica_2098 IPR025867 MnmE, helical domain Spica_2098 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2098 IPR005225 Small GTP-binding protein domain Spica_2098 IPR006073 GTP binding domain Spica_2099 IPR020595 MnmG-related, conserved site Spica_2099 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related Spica_2099 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG Spica_2099 IPR026904 GidA associated domain 3 Spica_2099 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2100 IPR011767 Glutaredoxin active site Spica_2100 IPR011911 Glutaredoxin-like protein, YruB Spica_2100 IPR036249 Thioredoxin-like superfamily Spica_2100 IPR002109 Glutaredoxin Spica_2107 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Spica_2107 IPR034683 Cytidylyltransferase IspD/TarI Spica_2107 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Spica_2107 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site Spica_2107 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily Spica_2107 IPR029044 Nucleotide-diphospho-sugar transferases Spica_2107 IPR026596 Bifunctional enzyme IspD/IspF Spica_2108 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily Spica_2108 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site Spica_2108 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Spica_2109 IPR011257 DNA glycosylase Spica_2109 IPR004036 Endonuclease III-like, conserved site-2 Spica_2109 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif Spica_2109 IPR003265 HhH-GPD domain Spica_2109 IPR005759 Endonuclease III Spica_2109 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Spica_2109 IPR004035 Endonuclease III, iron-sulphur binding site Spica_2109 IPR000445 Helix-hairpin-helix motif Spica_2111 IPR037512 Phosphoglycolate phosphatase, prokaryotic Spica_2111 IPR006346 2-phosphoglycolate phosphatase-like, prokaryotic Spica_2111 IPR023198 Phosphoglycolate phosphatase-like, domain 2 Spica_2111 IPR023214 HAD superfamily Spica_2111 IPR041492 Haloacid dehalogenase-like hydrolase Spica_2111 IPR006439 HAD hydrolase, subfamily IA Spica_2111 IPR036412 HAD-like superfamily Spica_2113 IPR003400 Biopolymer transport protein ExbD/TolR Spica_2114 IPR002898 MotA/TolQ/ExbB proton channel Spica_2118 IPR000843 LacI-type HTH domain Spica_2118 IPR010982 Lambda repressor-like, DNA-binding domain superfamily Spica_2118 IPR028082 Periplasmic binding protein-like I Spica_2119 IPR006047 Glycosyl hydrolase, family 13, catalytic domain Spica_2119 IPR013780 Glycosyl hydrolase, all-beta Spica_2119 IPR017853 Glycoside hydrolase superfamily Spica_2120 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2120 IPR035906 MetI-like superfamily Spica_2121 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2121 IPR035906 MetI-like superfamily Spica_2124 IPR001207 Transposase, mutator type Spica_2127 IPR029151 Periplasmic sensor-like domain superfamily Spica_2127 IPR018842 YkuI, C-terminal Spica_2127 IPR001633 EAL domain Spica_2127 IPR035919 EAL domain superfamily Spica_2128 IPR003660 HAMP domain Spica_2128 IPR004090 Chemotaxis methyl-accepting receptor Spica_2128 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain Spica_2128 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_2129 IPR010914 RsgA GTPase domain Spica_2129 IPR004881 Ribosome biogenesis GTPase RsgA Spica_2129 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2129 IPR030378 Circularly permuted (CP)-type guanine nucleotide-binding (G) domain Spica_2130 IPR011006 CheY-like superfamily Spica_2130 IPR016032 Signal transduction response regulator, C-terminal effector Spica_2130 IPR001789 Signal transduction response regulator, receiver domain Spica_2130 IPR000792 Transcription regulator LuxR, C-terminal Spica_2131 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2131 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2131 IPR005467 Histidine kinase domain Spica_2131 IPR017202 Sensor histidine kinase LiaS/VraS Spica_2131 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain Spica_2131 IPR003660 HAMP domain Spica_2133 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2133 IPR017871 ABC transporter, conserved site Spica_2133 IPR003593 AAA+ ATPase domain Spica_2133 IPR003439 ABC transporter-like Spica_2136 IPR011701 Major facilitator superfamily Spica_2136 IPR036259 MFS transporter superfamily Spica_2138 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Spica_2138 IPR019998 Membrane insertase YidC Spica_2138 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 Spica_2139 IPR037522 HD-GYP domain Spica_2139 IPR001789 Signal transduction response regulator, receiver domain Spica_2139 IPR003607 HD/PDEase domain Spica_2139 IPR011006 CheY-like superfamily Spica_2140 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2140 IPR017871 ABC transporter, conserved site Spica_2140 IPR013611 Transport-associated OB, type 2 Spica_2140 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit Spica_2140 IPR003439 ABC transporter-like Spica_2140 IPR008995 Molybdate/tungstate binding, C-terminal Spica_2140 IPR017879 ABC transporter, spermidine/putrescine import ATP-binding protein, PotA Spica_2140 IPR003593 AAA+ ATPase domain Spica_2141 IPR035906 MetI-like superfamily Spica_2141 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2142 IPR035906 MetI-like superfamily Spica_2142 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2143 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein Spica_2143 IPR006059 Bacterial extracellular solute-binding protein Spica_2144 IPR006070 YrdC-like domain Spica_2144 IPR023535 Threonylcarbamoyl-AMP synthase Spica_2144 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily Spica_2145 IPR000802 Arsenical pump membrane protein, ArsB Spica_2145 IPR004680 Citrate transporter-like domain Spica_2146 IPR002197 DNA binding HTH domain, Fis-type Spica_2146 IPR009057 Homeobox-like domain superfamily Spica_2146 IPR011006 CheY-like superfamily Spica_2146 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2146 IPR001789 Signal transduction response regulator, receiver domain Spica_2146 IPR002078 RNA polymerase sigma factor 54 interaction domain Spica_2146 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_2146 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_2146 IPR025944 Sigma-54 interaction domain, conserved site Spica_2146 IPR003593 AAA+ ATPase domain Spica_2146 IPR010114 DNA-binding transcriptional regulator NtrC Spica_2147 IPR010559 Signal transduction histidine kinase, internal region Spica_2147 IPR033479 Double Cache domain 1 Spica_2147 IPR003660 HAMP domain Spica_2147 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2147 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2147 IPR005467 Histidine kinase domain Spica_2147 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_2148 IPR028082 Periplasmic binding protein-like I Spica_2148 IPR000843 LacI-type HTH domain Spica_2148 IPR010982 Lambda repressor-like, DNA-binding domain superfamily Spica_2149 IPR003593 AAA+ ATPase domain Spica_2149 IPR003439 ABC transporter-like Spica_2149 IPR015861 ABC transporter, ribose import, RbsA Spica_2149 IPR017871 ABC transporter, conserved site Spica_2149 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2150 IPR001851 ABC transporter, permease Spica_2151 IPR030159 Autoinducer 2 ABC transporter, substrate-binding protein LsrB Spica_2151 IPR028082 Periplasmic binding protein-like I Spica_2151 IPR025997 Periplasmic binding protein Spica_2152 IPR035520 High-affinity zinc uptake system protein ZnuA Spica_2152 IPR006127 Periplasmic solute binding protein, ZnuA-like Spica_2153 IPR003439 ABC transporter-like Spica_2153 IPR003593 AAA+ ATPase domain Spica_2153 IPR017871 ABC transporter, conserved site Spica_2153 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2154 IPR001626 ABC transporter, TroCD-like Spica_2154 IPR037294 ABC transporter, BtuC-like Spica_2156 IPR040452 Sugar fermentation stimulation protein, C-terminal Spica_2156 IPR041465 SfsA, N-terminal OB domain Spica_2156 IPR005224 Sugar fermentation stimulation protein Spica_2157 IPR000620 EamA domain Spica_2159 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family Spica_2159 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily Spica_2163 IPR036390 Winged helix DNA-binding domain superfamily Spica_2163 IPR005119 LysR, substrate-binding Spica_2163 IPR000847 Transcription regulator HTH, LysR Spica_2163 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2164 IPR018383 Uncharacterised protein family UPF0324, prokaryote Spica_2164 IPR004630 Uncharacterised protein family UPF0324, bacteria Spica_2165 IPR011701 Major facilitator superfamily Spica_2165 IPR020846 Major facilitator superfamily domain Spica_2165 IPR036259 MFS transporter superfamily Spica_2165 IPR005829 Sugar transporter, conserved site Spica_2165 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG Spica_2167 IPR001046 NRAMP family Spica_2169 IPR001757 P-type ATPase Spica_2169 IPR006415 P-type ATPase, subfamily IIIB Spica_2169 IPR023214 HAD superfamily Spica_2169 IPR006068 Cation-transporting P-type ATPase, C-terminal Spica_2169 IPR036412 HAD-like superfamily Spica_2169 IPR008250 P-type ATPase, A domain superfamily Spica_2169 IPR023298 P-type ATPase, transmembrane domain superfamily Spica_2169 IPR018303 P-type ATPase, phosphorylation site Spica_2169 IPR004014 Cation-transporting P-type ATPase, N-terminal Spica_2169 IPR023299 P-type ATPase, cytoplasmic domain N Spica_2171 IPR019897 RidA, conserved site Spica_2171 IPR006056 RidA family Spica_2171 IPR035959 RutC-like superfamily Spica_2171 IPR006175 YjgF/YER057c/UK114 family Spica_2180 IPR036523 SurE-like phosphatase/nucleotidase superfamily Spica_2180 IPR030048 Survival protein SurE Spica_2180 IPR002828 Survival protein SurE-like phosphatase/nucleotidase Spica_2183 IPR001584 Integrase, catalytic core Spica_2183 IPR012337 Ribonuclease H-like superfamily Spica_2183 IPR036397 Ribonuclease H superfamily Spica_2183 IPR025948 HTH-like domain Spica_2213 IPR010559 Signal transduction histidine kinase, internal region Spica_2213 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_2213 IPR005467 Histidine kinase domain Spica_2213 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2213 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2213 IPR033479 Double Cache domain 1 Spica_2213 IPR003660 HAMP domain Spica_2214 IPR018060 DNA binding HTH domain, AraC-type Spica_2214 IPR001789 Signal transduction response regulator, receiver domain Spica_2214 IPR011006 CheY-like superfamily Spica_2214 IPR009057 Homeobox-like domain superfamily Spica_2215 IPR033893 ABC transporter periplasmic-binding protein YtfQ Spica_2215 IPR028082 Periplasmic binding protein-like I Spica_2215 IPR025997 Periplasmic binding protein Spica_2216 IPR033893 ABC transporter periplasmic-binding protein YtfQ Spica_2216 IPR028082 Periplasmic binding protein-like I Spica_2216 IPR025997 Periplasmic binding protein Spica_2217 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2217 IPR017871 ABC transporter, conserved site Spica_2217 IPR003439 ABC transporter-like Spica_2217 IPR003593 AAA+ ATPase domain Spica_2218 IPR001851 ABC transporter, permease Spica_2219 IPR001851 ABC transporter, permease Spica_2220 IPR013785 Aldolase-type TIM barrel Spica_2220 IPR031704 Glycosyl hydrolase family 36, N-terminal Spica_2220 IPR017853 Glycoside hydrolase superfamily Spica_2220 IPR031705 Glycosyl hydrolase family 36, C-terminal Spica_2220 IPR002252 Glycoside hydrolase family 36 Spica_2220 IPR038417 Alpha-galactosidase, N-terminal domain superfamily Spica_2220 IPR013780 Glycosyl hydrolase, all-beta Spica_2220 IPR000111 Glycoside hydrolase family 27/36, conserved site Spica_2222 IPR030165 sn-Glycerol-3-phosphate transport system permease protein UgpE Spica_2222 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2222 IPR035906 MetI-like superfamily Spica_2223 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2223 IPR035906 MetI-like superfamily Spica_2224 IPR028082 Periplasmic binding protein-like I Spica_2224 IPR010982 Lambda repressor-like, DNA-binding domain superfamily Spica_2224 IPR000843 LacI-type HTH domain Spica_2226 IPR001233 tRNA-splicing ligase, RtcB Spica_2226 IPR036025 tRNA-splicing ligase RtcB-like superfamily Spica_2234 IPR000286 Histone deacetylase family Spica_2234 IPR023801 Histone deacetylase domain Spica_2234 IPR023696 Ureohydrolase domain superfamily Spica_2234 IPR037138 Histone deacetylase domain superfamily Spica_2239 IPR003593 AAA+ ATPase domain Spica_2239 IPR003439 ABC transporter-like Spica_2239 IPR017871 ABC transporter, conserved site Spica_2239 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2240 IPR018080 Band 7/stomatin-like, conserved site Spica_2240 IPR001972 Stomatin family Spica_2240 IPR001107 Band 7 domain Spica_2240 IPR036013 Band 7/SPFH domain superfamily Spica_2241 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2241 IPR036390 Winged helix DNA-binding domain superfamily Spica_2241 IPR000524 Transcription regulator HTH, GntR Spica_2242 IPR038393 L-fucose isomerase, domain 3 superfamily Spica_2242 IPR004216 L-fucose/L-arabinose isomerase, C-terminal Spica_2242 IPR015888 L-fucose isomerase, C-terminal Spica_2242 IPR012889 L-fucose isomerase, N-terminal-2 Spica_2242 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily Spica_2242 IPR012888 L-fucose isomerase, N-terminal-1 Spica_2242 IPR038392 L-fucose isomerase, domain 2 superfamily Spica_2242 IPR038391 L-fucose isomerase, domain 1 superfamily Spica_2242 IPR005763 L-fucose isomerase Spica_2243 IPR010982 Lambda repressor-like, DNA-binding domain superfamily Spica_2243 IPR000843 LacI-type HTH domain Spica_2243 IPR028082 Periplasmic binding protein-like I Spica_2245 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU Spica_2245 IPR023750 RbsD-like superfamily Spica_2245 IPR023751 L-fucose mutarotase Spica_2247 IPR013149 Alcohol dehydrogenase, C-terminal Spica_2247 IPR013154 Alcohol dehydrogenase, N-terminal Spica_2247 IPR011032 GroES-like superfamily Spica_2247 IPR036291 NAD(P)-binding domain superfamily Spica_2248 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site Spica_2248 IPR017583 Tagatose/fructose phosphokinase Spica_2248 IPR022463 Fructose 1-phosphate kinase Spica_2248 IPR029056 Ribokinase-like Spica_2248 IPR011611 Carbohydrate kinase PfkB Spica_2249 IPR000032 Phosphocarrier protein HPr-like Spica_2249 IPR002114 Phosphotransferase system, HPr serine phosphorylation site Spica_2249 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site Spica_2249 IPR035895 HPr-like superfamily Spica_2250 IPR006318 Phosphotransferase system, enzyme I-like Spica_2250 IPR008731 Phosphotransferase system, enzyme I N-terminal Spica_2250 IPR024692 Phosphotransferase system, enzyme I Spica_2250 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily Spica_2250 IPR023151 PEP-utilising enzyme, conserved site Spica_2250 IPR000121 PEP-utilising enzyme, C-terminal Spica_2250 IPR036637 Phosphohistidine domain superfamily Spica_2250 IPR008279 PEP-utilising enzyme, mobile domain Spica_2250 IPR018274 PEP-utilising enzyme, active site Spica_2250 IPR040442 Pyruvate kinase-like domain superfamily Spica_2250 IPR036618 PtsI, HPr-binding domain superfamily Spica_2251 IPR016152 Phosphotransferase/anion transporter Spica_2251 IPR002178 PTS EIIA type-2 domain Spica_2252 IPR002178 PTS EIIA type-2 domain Spica_2252 IPR016152 Phosphotransferase/anion transporter Spica_2252 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2252 IPR036095 PTS system IIB component-like superfamily Spica_2252 IPR013196 Helix-turn-helix, type 11 Spica_2252 IPR013011 Phosphotransferase system, EIIB component, type 2 Spica_2252 IPR036390 Winged helix DNA-binding domain superfamily Spica_2252 IPR003501 Phosphotransferase system, EIIB component, type 2/3 Spica_2252 IPR007737 Mga helix-turn-helix domain Spica_2252 IPR036634 PRD domain superfamily Spica_2252 IPR011608 PRD domain Spica_2253 IPR036095 PTS system IIB component-like superfamily Spica_2253 IPR013011 Phosphotransferase system, EIIB component, type 2 Spica_2253 IPR029503 Phosphotransferase system EIIB component, mannitol-specific Spica_2253 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC Spica_2253 IPR013014 Phosphotransferase system, EIIC component, type 2 Spica_2253 IPR003352 Phosphotransferase system, EIIC Spica_2253 IPR003501 Phosphotransferase system, EIIB component, type 2/3 Spica_2256 IPR002528 Multi antimicrobial extrusion protein Spica_2257 IPR029056 Ribokinase-like Spica_2257 IPR011611 Carbohydrate kinase PfkB Spica_2257 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site Spica_2258 IPR001765 Carbonic anhydrase Spica_2258 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site Spica_2258 IPR036874 Carbonic anhydrase superfamily Spica_2261 IPR003679 Aminoglycoside N(3)-acetyltransferase Spica_2261 IPR028345 Aminoglycoside 3-N-acetyltransferase-like Spica_2262 IPR023299 P-type ATPase, cytoplasmic domain N Spica_2262 IPR023298 P-type ATPase, transmembrane domain superfamily Spica_2262 IPR036412 HAD-like superfamily Spica_2262 IPR023214 HAD superfamily Spica_2262 IPR017969 Heavy-metal-associated, conserved site Spica_2262 IPR006121 Heavy metal-associated domain, HMA Spica_2262 IPR036163 Heavy metal-associated domain superfamily Spica_2262 IPR027256 P-type ATPase, subfamily IB Spica_2262 IPR001757 P-type ATPase Spica_2262 IPR018303 P-type ATPase, phosphorylation site Spica_2262 IPR008250 P-type ATPase, A domain superfamily Spica_2263 IPR001845 HTH ArsR-type DNA-binding domain Spica_2263 IPR018334 ArsR-type transcription regulator, HTH motif Spica_2263 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2263 IPR036390 Winged helix DNA-binding domain superfamily Spica_2263 IPR011991 ArsR-like helix-turn-helix domain Spica_2266 IPR015797 NUDIX hydrolase-like domain superfamily Spica_2266 IPR020476 NUDIX hydrolase Spica_2266 IPR020084 NUDIX hydrolase, conserved site Spica_2266 IPR000086 NUDIX hydrolase domain Spica_2270 IPR011547 SLC26A/SulP transporter domain Spica_2270 IPR001902 SLC26A/SulP transporter Spica_2270 IPR002645 STAS domain Spica_2270 IPR036513 STAS domain superfamily Spica_2273 IPR036640 ABC transporter type 1, transmembrane domain superfamily Spica_2273 IPR011527 ABC transporter type 1, transmembrane domain Spica_2273 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2273 IPR039421 Type I protein exporter Spica_2273 IPR003439 ABC transporter-like Spica_2273 IPR003593 AAA+ ATPase domain Spica_2283 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2283 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain Spica_2283 IPR005467 Histidine kinase domain Spica_2283 IPR017202 Sensor histidine kinase LiaS/VraS Spica_2283 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2283 IPR003660 HAMP domain Spica_2284 IPR011006 CheY-like superfamily Spica_2284 IPR016032 Signal transduction response regulator, C-terminal effector Spica_2284 IPR001789 Signal transduction response regulator, receiver domain Spica_2284 IPR000792 Transcription regulator LuxR, C-terminal Spica_2285 IPR006059 Bacterial extracellular solute-binding protein Spica_2286 IPR035906 MetI-like superfamily Spica_2286 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2287 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2287 IPR035906 MetI-like superfamily Spica_2289 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily Spica_2289 IPR037171 NagB/RpiA transferase-like Spica_2289 IPR002698 5-formyltetrahydrofolate cyclo-ligase Spica_2293 IPR036249 Thioredoxin-like superfamily Spica_2293 IPR013766 Thioredoxin domain Spica_2293 IPR002065 Thiol peroxidase Tpx Spica_2293 IPR018219 Thiol peroxidase conserved site Spica_2293 IPR013740 Redoxin Spica_2298 IPR002018 Carboxylesterase, type B Spica_2298 IPR029058 Alpha/Beta hydrolase fold Spica_2298 IPR000997 Cholinesterase Spica_2298 IPR019819 Carboxylesterase type B, conserved site Spica_2298 IPR019826 Carboxylesterase type B, active site Spica_2301 IPR000182 GNAT domain Spica_2301 IPR016181 Acyl-CoA N-acyltransferase Spica_2305 IPR036259 MFS transporter superfamily Spica_2305 IPR011701 Major facilitator superfamily Spica_2306 IPR004485 Cobalamin biosynthesis CobD/CbiB Spica_2308 IPR000453 Chorismate synthase Spica_2308 IPR035904 Chorismate synthase AroC superfamily Spica_2308 IPR020541 Chorismate synthase, conserved site Spica_2309 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2309 IPR041628 ChlI/MoxR, AAA lid domain Spica_2309 IPR011703 ATPase, AAA-3 Spica_2315 IPR041628 ChlI/MoxR, AAA lid domain Spica_2315 IPR011703 ATPase, AAA-3 Spica_2315 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2316 IPR001851 ABC transporter, permease Spica_2317 IPR001851 ABC transporter, permease Spica_2318 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2318 IPR017871 ABC transporter, conserved site Spica_2318 IPR003439 ABC transporter-like Spica_2318 IPR003593 AAA+ ATPase domain Spica_2319 IPR033893 ABC transporter periplasmic-binding protein YtfQ Spica_2319 IPR028082 Periplasmic binding protein-like I Spica_2319 IPR025997 Periplasmic binding protein Spica_2320 IPR028082 Periplasmic binding protein-like I Spica_2320 IPR033893 ABC transporter periplasmic-binding protein YtfQ Spica_2320 IPR025997 Periplasmic binding protein Spica_2321 IPR033479 Double Cache domain 1 Spica_2321 IPR003660 HAMP domain Spica_2321 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2321 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2321 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_2321 IPR010559 Signal transduction histidine kinase, internal region Spica_2321 IPR005467 Histidine kinase domain Spica_2322 IPR001789 Signal transduction response regulator, receiver domain Spica_2322 IPR011006 CheY-like superfamily Spica_2322 IPR009057 Homeobox-like domain superfamily Spica_2322 IPR018060 DNA binding HTH domain, AraC-type Spica_2323 IPR025110 AMP-binding enzyme, C-terminal domain Spica_2323 IPR020845 AMP-binding, conserved site Spica_2323 IPR042099 AMP-dependent synthetase-like superfamily Spica_2323 IPR000873 AMP-dependent synthetase/ligase Spica_2326 IPR037171 NagB/RpiA transferase-like Spica_2326 IPR004788 Ribose 5-phosphate isomerase, type A Spica_2326 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup Spica_2328 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase Spica_2328 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal Spica_2328 IPR011342 Shikimate dehydrogenase Spica_2328 IPR036291 NAD(P)-binding domain superfamily Spica_2328 IPR022893 Shikimate dehydrogenase family Spica_2330 IPR020845 AMP-binding, conserved site Spica_2330 IPR042099 AMP-dependent synthetase-like superfamily Spica_2330 IPR000873 AMP-dependent synthetase/ligase Spica_2332 IPR005543 PASTA domain Spica_2333 IPR005794 Methionyl-tRNA formyltransferase Spica_2333 IPR011034 Formyl transferase-like, C-terminal domain superfamily Spica_2333 IPR041711 Methionyl-tRNA formyltransferase, N-terminal domain Spica_2333 IPR002376 Formyl transferase, N-terminal Spica_2333 IPR037022 Formyl transferase, C-terminal domain superfamily Spica_2333 IPR005793 Formyl transferase, C-terminal Spica_2333 IPR036477 Formyl transferase, N-terminal domain superfamily Spica_2334 IPR036821 Peptide deformylase superfamily Spica_2334 IPR023635 Peptide deformylase Spica_2335 IPR001460 Penicillin-binding protein, transpeptidase Spica_2335 IPR036950 Penicillin binding protein transglycosylase domain Spica_2335 IPR009647 Penicillin-binding, C-terminal Spica_2335 IPR001264 Glycosyl transferase, family 51 Spica_2335 IPR023346 Lysozyme-like domain superfamily Spica_2335 IPR011815 Penicillin-binding protein 1C Spica_2335 IPR012338 Beta-lactamase/transpeptidase-like Spica_2336 IPR041462 Bacterial Alpha-2-macroglobulin, MG6 domain Spica_2336 IPR041246 Bacterial alpha-2-macroglobulin MG10 domain Spica_2336 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid Spica_2336 IPR021868 Alpha-2-macroglobulin MG3 domain Spica_2336 IPR011625 Alpha-2-macroglobulin, bait region domain Spica_2336 IPR002890 Macroglobulin domain Spica_2336 IPR041203 Bacterial Alpha-2-macroglobulin, MG5 domain Spica_2336 IPR001599 Alpha-2-macroglobulin Spica_2337 IPR013515 Phytochrome, central region Spica_2337 IPR001294 Phytochrome Spica_2337 IPR029787 Nucleotide cyclase Spica_2337 IPR016132 Phytochrome chromophore attachment domain Spica_2337 IPR000160 GGDEF domain Spica_2337 IPR029016 GAF-like domain superfamily Spica_2337 IPR003018 GAF domain Spica_2337 IPR035919 EAL domain superfamily Spica_2337 IPR001633 EAL domain Spica_2338 IPR011006 CheY-like superfamily Spica_2338 IPR001789 Signal transduction response regulator, receiver domain Spica_2338 IPR035909 Methylesterase CheB, C-terminal Spica_2338 IPR008248 Protein-glutamate methylesterase/protein-glutamine glutaminase, CheB type Spica_2338 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase Spica_2339 IPR011324 Cytotoxic necrotizing factor-like, catalytic Spica_2339 IPR005659 Chemoreceptor glutamine deamidase CheD Spica_2339 IPR038592 CheD-like superfamily Spica_2340 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal Spica_2340 IPR000780 MCP methyltransferase, CheR-type Spica_2340 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal Spica_2340 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily Spica_2340 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_2341 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding Spica_2341 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_2341 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain superfamily Spica_2341 IPR004090 Chemotaxis methyl-accepting receptor Spica_2341 IPR004091 Chemotaxis methyl-accepting receptor, methyl-accepting site Spica_2341 IPR003660 HAMP domain Spica_2342 IPR002545 CheW-like domain Spica_2342 IPR039315 Chemotaxis protein CheW Spica_2342 IPR036061 CheW-like domain superfamily Spica_2343 IPR039420 Transcriptional regulatory protein WalR-like Spica_2343 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2343 IPR011006 CheY-like superfamily Spica_2343 IPR001789 Signal transduction response regulator, receiver domain Spica_2343 IPR001867 OmpR/PhoB-type DNA-binding domain Spica_2344 IPR002545 CheW-like domain Spica_2344 IPR035891 CheY-binding domain of CheA Spica_2344 IPR036061 CheW-like domain superfamily Spica_2344 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2344 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding Spica_2344 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily Spica_2344 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily Spica_2344 IPR036641 HPT domain superfamily Spica_2344 IPR004105 Histidine kinase CheA-like, homodimeric domain Spica_2344 IPR005467 Histidine kinase domain Spica_2344 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_2344 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_2344 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain Spica_2344 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2346 IPR011006 CheY-like superfamily Spica_2346 IPR001867 OmpR/PhoB-type DNA-binding domain Spica_2346 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response Spica_2346 IPR016032 Signal transduction response regulator, C-terminal effector Spica_2346 IPR001789 Signal transduction response regulator, receiver domain Spica_2346 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2346 IPR039420 Transcriptional regulatory protein WalR-like Spica_2347 IPR011032 GroES-like superfamily Spica_2347 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site Spica_2347 IPR036291 NAD(P)-binding domain superfamily Spica_2347 IPR013154 Alcohol dehydrogenase, N-terminal Spica_2347 IPR013149 Alcohol dehydrogenase, C-terminal Spica_2347 IPR020843 Polyketide synthase, enoylreductase domain Spica_2348 IPR018170 Aldo/keto reductase, conserved site Spica_2348 IPR020471 Aldo/keto reductase Spica_2348 IPR023210 NADP-dependent oxidoreductase domain Spica_2348 IPR036812 NADP-dependent oxidoreductase domain superfamily Spica_2349 IPR001761 Periplasmic binding protein/LacI sugar binding domain Spica_2349 IPR010982 Lambda repressor-like, DNA-binding domain superfamily Spica_2349 IPR023588 Transcription regulator HTH, PurR Spica_2349 IPR028082 Periplasmic binding protein-like I Spica_2349 IPR000843 LacI-type HTH domain Spica_2351 IPR036678 MutS, connector domain superfamily Spica_2351 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2351 IPR007860 DNA mismatch repair protein MutS, connector domain Spica_2351 IPR036187 DNA mismatch repair protein MutS, core domain superfamily Spica_2351 IPR016151 DNA mismatch repair protein MutS, N-terminal Spica_2351 IPR005748 DNA mismatch repair protein MutS Spica_2351 IPR007861 DNA mismatch repair protein MutS, clamp Spica_2351 IPR000432 DNA mismatch repair protein MutS, C-terminal Spica_2351 IPR007695 DNA mismatch repair protein MutS-like, N-terminal Spica_2351 IPR017261 DNA mismatch repair protein MutS/MSH Spica_2351 IPR007696 DNA mismatch repair protein MutS, core Spica_2352 IPR036187 DNA mismatch repair protein MutS, core domain superfamily Spica_2352 IPR002625 Smr domain Spica_2352 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2352 IPR005747 Endonuclease MutS2 Spica_2352 IPR036063 Smr domain superfamily Spica_2352 IPR007696 DNA mismatch repair protein MutS, core Spica_2352 IPR000432 DNA mismatch repair protein MutS, C-terminal Spica_2352 IPR003593 AAA+ ATPase domain Spica_2357 IPR022903 Glycine cleavage system T protein, bacteria Spica_2357 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain Spica_2357 IPR028896 Aminomethyltransferase-like Spica_2357 IPR006223 Glycine cleavage system T protein Spica_2357 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 Spica_2357 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal Spica_2357 IPR006222 Aminomethyltransferase, folate-binding domain Spica_2358 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Spica_2358 IPR000089 Biotin/lipoyl attachment Spica_2358 IPR002930 Glycine cleavage system H-protein Spica_2358 IPR033753 Glycine cleavage system H-protein/Simiate Spica_2358 IPR017453 Glycine cleavage system H-protein, subgroup Spica_2358 IPR011053 Single hybrid motif Spica_2359 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_2359 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_2359 IPR015424 Pyridoxal phosphate-dependent transferase Spica_2359 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 Spica_2359 IPR020581 Glycine cleavage system P protein Spica_2360 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 Spica_2360 IPR015424 Pyridoxal phosphate-dependent transferase Spica_2360 IPR020581 Glycine cleavage system P protein Spica_2360 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_2360 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_2363 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain Spica_2363 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Spica_2363 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site Spica_2363 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding Spica_2363 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily Spica_2363 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2363 IPR023546 Methylated-DNA--protein-cysteine methyltransferase Spica_2365 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_2365 IPR041698 Methyltransferase domain 25 Spica_2366 IPR005835 Nucleotidyl transferase domain Spica_2366 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal Spica_2366 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Spica_2366 IPR011051 RmlC-like cupin domain superfamily Spica_2366 IPR014710 RmlC-like jelly roll fold Spica_2366 IPR029044 Nucleotide-diphospho-sugar transferases Spica_2367 IPR000890 Aliphatic acid kinase, short-chain Spica_2367 IPR023865 Aliphatic acid kinase, short-chain, conserved site Spica_2367 IPR004372 Acetate/propionate kinase Spica_2368 IPR029056 Ribokinase-like Spica_2368 IPR002139 Ribokinase/fructokinase Spica_2368 IPR011611 Carbohydrate kinase PfkB Spica_2368 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site Spica_2369 IPR029062 Class I glutamine amidotransferase-like Spica_2369 IPR002818 DJ-1/PfpI Spica_2369 IPR006287 Protein/nucleic acid deglycase DJ-1 Spica_2370 IPR011006 CheY-like superfamily Spica_2370 IPR001867 OmpR/PhoB-type DNA-binding domain Spica_2370 IPR006291 Transcriptional regulatory protein PcoR, heavy metal response Spica_2370 IPR016032 Signal transduction response regulator, C-terminal effector Spica_2370 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2370 IPR039420 Transcriptional regulatory protein WalR-like Spica_2370 IPR001789 Signal transduction response regulator, receiver domain Spica_2371 IPR005467 Histidine kinase domain Spica_2371 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_2371 IPR019247 Histidine kinase BarA, N-terminal Spica_2371 IPR036641 HPT domain superfamily Spica_2371 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_2371 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain Spica_2371 IPR001789 Signal transduction response regulator, receiver domain Spica_2371 IPR003660 HAMP domain Spica_2371 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2371 IPR011006 CheY-like superfamily Spica_2371 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_2371 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2372 IPR010140 Histidinol phosphate phosphatase, HisJ Spica_2372 IPR004013 PHP domain Spica_2372 IPR016195 Polymerase/histidinol phosphatase-like Spica_2374 IPR004368 Translation initiation factor IF-1 Spica_2374 IPR012340 Nucleic acid-binding, OB-fold Spica_2374 IPR006196 RNA-binding domain, S1, IF1 type Spica_2374 IPR022967 RNA-binding domain, S1 Spica_2375 IPR002625 Smr domain Spica_2375 IPR036063 Smr domain superfamily Spica_2375 IPR022990 Uncharacterised protein family UPF0115 Spica_2381 IPR002881 Domain of unknown function DUF58 Spica_2381 IPR036465 von Willebrand factor A-like domain superfamily Spica_2382 IPR011703 ATPase, AAA-3 Spica_2382 IPR041628 ChlI/MoxR, AAA lid domain Spica_2382 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2390 IPR004095 TGS Spica_2390 IPR023192 TGS-like domain superfamily Spica_2390 IPR012676 TGS-like Spica_2390 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2390 IPR006073 GTP binding domain Spica_2390 IPR031167 OBG-type guanine nucleotide-binding (G) domain Spica_2390 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 Spica_2390 IPR013029 YchF, C-terminal domain Spica_2390 IPR041706 YchF, N-terminal Spica_2390 IPR012675 Beta-grasp domain superfamily Spica_2392 IPR005786 Branched-chain amino acid aminotransferase II Spica_2392 IPR033939 Branched-chain aminotransferase Spica_2392 IPR036038 Aminotransferase-like, PLP-dependent enzymes Spica_2392 IPR018300 Aminotransferase, class IV, conserved site Spica_2392 IPR001544 Aminotransferase class IV Spica_2394 IPR036621 Anticodon-binding domain superfamily Spica_2394 IPR002320 Threonine-tRNA ligase, class IIa Spica_2394 IPR033728 Threonine-tRNA ligase catalytic core domain Spica_2394 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) Spica_2394 IPR012947 Threonyl/alanyl tRNA synthetase, SAD Spica_2394 IPR004154 Anticodon-binding Spica_2394 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily Spica_2394 IPR006195 Aminoacyl-tRNA synthetase, class II Spica_2398 IPR010074 Phosphoribosylformylglycinamidine subunit PurL Spica_2398 IPR041609 Phosphoribosylformylglycinamidine synthase, linker domain Spica_2398 IPR010918 PurM-like, C-terminal domain Spica_2398 IPR036676 PurM-like, C-terminal domain superfamily Spica_2398 IPR016188 PurM-like, N-terminal domain Spica_2398 IPR036921 PurM-like, N-terminal domain superfamily Spica_2399 IPR003660 HAMP domain Spica_2399 IPR029151 Periplasmic sensor-like domain superfamily Spica_2399 IPR033479 Double Cache domain 1 Spica_2399 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_2401 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_2401 IPR003694 NAD(+) synthetase Spica_2401 IPR022310 NAD/GMP synthase Spica_2401 IPR014445 Glutamine-dependent NAD(+) synthetase Spica_2401 IPR036526 Carbon-nitrogen hydrolase superfamily Spica_2401 IPR003010 Carbon-nitrogen hydrolase Spica_2402 IPR029052 Metallo-dependent phosphatase-like Spica_2402 IPR019079 Capsule synthesis protein, CapA Spica_2403 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2403 IPR011006 CheY-like superfamily Spica_2403 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2403 IPR005467 Histidine kinase domain Spica_2403 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_2403 IPR000014 PAS domain Spica_2403 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_2403 IPR013656 PAS fold-4 Spica_2403 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_2403 IPR001789 Signal transduction response regulator, receiver domain Spica_2403 IPR035965 PAS domain superfamily Spica_2405 IPR018974 Tex-like protein, N-terminal Spica_2405 IPR023323 Tex-like domain superfamily Spica_2405 IPR023319 Tex-like protein, HTH domain superfamily Spica_2405 IPR022967 RNA-binding domain, S1 Spica_2405 IPR010994 RuvA domain 2-like Spica_2405 IPR032639 Tex protein, YqgF-like domain Spica_2405 IPR041692 HHH domain 9 Spica_2405 IPR037027 YqgF/RNase H-like domain superfamily Spica_2405 IPR012337 Ribonuclease H-like superfamily Spica_2405 IPR012340 Nucleic acid-binding, OB-fold Spica_2405 IPR006641 YqgF/RNase H-like domain Spica_2405 IPR003029 S1 domain Spica_2406 IPR003682 rRNA small subunit methyltransferase G Spica_2406 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_2408 IPR029151 Periplasmic sensor-like domain superfamily Spica_2408 IPR033463 Single cache domain 3 Spica_2408 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_2408 IPR003660 HAMP domain Spica_2408 IPR004090 Chemotaxis methyl-accepting receptor Spica_2410 IPR005128 Alpha-acetolactate decarboxylase Spica_2412 IPR004090 Chemotaxis methyl-accepting receptor Spica_2412 IPR003660 HAMP domain Spica_2412 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain Spica_2412 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_2413 IPR018236 SAICAR synthetase, conserved site Spica_2413 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase Spica_2413 IPR028923 SAICAR synthetase/ADE2, N-terminal Spica_2413 IPR033934 Bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide synthase Spica_2414 IPR017932 Glutamine amidotransferase type 2 domain Spica_2414 IPR035584 Amidophosphoribosyltransferase, N-terminal Spica_2414 IPR029055 Nucleophile aminohydrolases, N-terminal Spica_2414 IPR000836 Phosphoribosyltransferase domain Spica_2414 IPR029057 Phosphoribosyltransferase-like Spica_2414 IPR005854 Amidophosphoribosyltransferase Spica_2415 IPR036676 PurM-like, C-terminal domain superfamily Spica_2415 IPR016188 PurM-like, N-terminal domain Spica_2415 IPR036921 PurM-like, N-terminal domain superfamily Spica_2415 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase Spica_2415 IPR010918 PurM-like, C-terminal domain Spica_2416 IPR004607 Phosphoribosylglycinamide formyltransferase Spica_2416 IPR001555 Phosphoribosylglycinamide formyltransferase, active site Spica_2416 IPR036477 Formyl transferase, N-terminal domain superfamily Spica_2416 IPR002376 Formyl transferase, N-terminal Spica_2417 IPR024051 AICAR transformylase, duplicated domain superfamily Spica_2417 IPR016193 Cytidine deaminase-like Spica_2417 IPR011607 Methylglyoxal synthase-like domain Spica_2417 IPR002695 Bifunctional purine biosynthesis protein PurH-like Spica_2417 IPR036914 Methylglyoxal synthase-like domain superfamily Spica_2418 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Spica_2418 IPR011761 ATP-grasp fold Spica_2418 IPR013815 ATP-grasp fold, subdomain 1 Spica_2418 IPR016185 Pre-ATP-grasp domain superfamily Spica_2418 IPR000115 Phosphoribosylglycinamide synthetase Spica_2418 IPR020560 Phosphoribosylglycinamide synthetase, C-domain Spica_2418 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily Spica_2418 IPR020559 Phosphoribosylglycinamide synthetase, conserved site Spica_2418 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal Spica_2418 IPR011054 Rudiment single hybrid motif Spica_2419 IPR009057 Homeobox-like domain superfamily Spica_2419 IPR001647 DNA-binding HTH domain, TetR-type Spica_2419 IPR023769 Nucleoid occlusion factor SlmA Spica_2419 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily Spica_2420 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2420 IPR035906 MetI-like superfamily Spica_2421 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2421 IPR035906 MetI-like superfamily Spica_2423 IPR011527 ABC transporter type 1, transmembrane domain Spica_2423 IPR003593 AAA+ ATPase domain Spica_2423 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2423 IPR039421 Type I protein exporter Spica_2423 IPR017871 ABC transporter, conserved site Spica_2423 IPR003439 ABC transporter-like Spica_2423 IPR036640 ABC transporter type 1, transmembrane domain superfamily Spica_2424 IPR011527 ABC transporter type 1, transmembrane domain Spica_2424 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2424 IPR003439 ABC transporter-like Spica_2424 IPR039421 Type I protein exporter Spica_2424 IPR036640 ABC transporter type 1, transmembrane domain superfamily Spica_2424 IPR003593 AAA+ ATPase domain Spica_2424 IPR017871 ABC transporter, conserved site Spica_2426 IPR022066 Signal transduction histidine kinase, N-terminal Spica_2426 IPR035965 PAS domain superfamily Spica_2426 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_2426 IPR005467 Histidine kinase domain Spica_2426 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2426 IPR038424 Signal transduction histidine kinase, N-terminal domain superfamily Spica_2426 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2427 IPR028082 Periplasmic binding protein-like I Spica_2427 IPR028081 Leucine-binding protein domain Spica_2427 IPR000709 Leu/Ile/Val-binding protein Spica_2428 IPR000873 AMP-dependent synthetase/ligase Spica_2428 IPR020845 AMP-binding, conserved site Spica_2428 IPR025110 AMP-binding enzyme, C-terminal domain Spica_2431 IPR011031 Multihaem cytochrome Spica_2431 IPR013087 Zinc finger C2H2-type Spica_2431 IPR012286 Tetrahaem cytochrome domain Spica_2431 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Spica_2431 IPR036280 Multiheme cytochrome superfamily Spica_2431 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Spica_2431 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2431 IPR010960 Flavocytochrome c Spica_2432 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Spica_2432 IPR013115 Histidine biosynthesis HisG, C-terminal Spica_2432 IPR001348 ATP phosphoribosyltransferase HisG Spica_2432 IPR013820 ATP phosphoribosyltransferase, catalytic domain Spica_2432 IPR020621 ATP phosphoribosyltransferase HisG, long form Spica_2432 IPR011322 Nitrogen regulatory PII-like, alpha/beta Spica_2433 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_2433 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site Spica_2433 IPR000807 Imidazoleglycerol-phosphate dehydratase Spica_2433 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily Spica_2434 IPR010139 Imidazole glycerol phosphate synthase, subunit H Spica_2434 IPR017926 Glutamine amidotransferase Spica_2434 IPR029062 Class I glutamine amidotransferase-like Spica_2435 IPR011060 Ribulose-phosphate binding barrel Spica_2435 IPR004651 Histidine biosynthesis, HisF Spica_2435 IPR006062 Histidine biosynthesis Spica_2435 IPR013785 Aldolase-type TIM barrel Spica_2436 IPR023019 Histidine biosynthesis bifunctional protein HisIE Spica_2436 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase Spica_2436 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like Spica_2436 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily Spica_2436 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain Spica_2437 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site Spica_2437 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_2437 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_2437 IPR015424 Pyridoxal phosphate-dependent transferase Spica_2437 IPR005861 Histidinol-phosphate aminotransferase family Spica_2437 IPR004839 Aminotransferase, class I/classII Spica_2438 IPR001692 Histidinol dehydrogenase, conserved site Spica_2438 IPR022695 Histidinol dehydrogenase, monofunctional Spica_2438 IPR012131 Histidinol dehydrogenase Spica_2438 IPR016161 Aldehyde/histidinol dehydrogenase Spica_2444 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily Spica_2444 IPR036966 Carbohydrate-binding module 3 superfamily Spica_2444 IPR018087 Glycoside hydrolase, family 5, conserved site Spica_2444 IPR017853 Glycoside hydrolase superfamily Spica_2444 IPR001956 Carbohydrate-binding module 3 Spica_2444 IPR001547 Glycoside hydrolase, family 5 Spica_2450 IPR018062 HTH domain AraC-type, conserved site Spica_2450 IPR018060 DNA binding HTH domain, AraC-type Spica_2450 IPR020449 Transcription regulator HTH, AraC- type Spica_2450 IPR009057 Homeobox-like domain superfamily Spica_2452 IPR035906 MetI-like superfamily Spica_2452 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2453 IPR035906 MetI-like superfamily Spica_2453 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2454 IPR006059 Bacterial extracellular solute-binding protein Spica_2455 IPR041542 Beta-xylosidase, C-terminal Concanavalin A-like domain Spica_2455 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Spica_2455 IPR006710 Glycoside hydrolase, family 43 Spica_2455 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Spica_2456 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily Spica_2456 IPR006710 Glycoside hydrolase, family 43 Spica_2456 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily Spica_2456 IPR041542 Beta-xylosidase, C-terminal Concanavalin A-like domain Spica_2460 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger Spica_2460 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain Spica_2460 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain Spica_2463 IPR011761 ATP-grasp fold Spica_2463 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type Spica_2463 IPR040686 Phosphoribosylaminoimidazole carboxylase, C-terminal domain Spica_2463 IPR013815 ATP-grasp fold, subdomain 1 Spica_2463 IPR016185 Pre-ATP-grasp domain superfamily Spica_2463 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit Spica_2463 IPR011054 Rudiment single hybrid motif Spica_2464 IPR024694 PurE, prokaryotic type Spica_2464 IPR000031 PurE domain Spica_2464 IPR033747 Class I PurE Spica_2464 IPR035893 PurE domain superfamily Spica_2471 IPR036390 Winged helix DNA-binding domain superfamily Spica_2471 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2471 IPR000600 ROK family Spica_2472 IPR032466 Metal-dependent hydrolase Spica_2472 IPR011059 Metal-dependent hydrolase, composite domain superfamily Spica_2472 IPR003764 N-acetylglucosamine-6-phosphate deacetylase Spica_2472 IPR006680 Amidohydrolase-related Spica_2473 IPR004547 Glucosamine-6-phosphate isomerase Spica_2473 IPR018321 Glucosamine-6-phosphate isomerase, conserved site Spica_2473 IPR037171 NagB/RpiA transferase-like Spica_2473 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase Spica_2475 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily Spica_2475 IPR006667 SLC41 divalent cation transporters, integral membrane domain Spica_2475 IPR006669 Magnesium transporter MgtE Spica_2475 IPR038048 Magnesium transporter MgtE, transmembrane domain Spica_2475 IPR000644 CBS domain Spica_2475 IPR038076 MgtE, N-terminal domain superfamily Spica_2475 IPR006668 Magnesium transporter, MgtE intracellular domain Spica_2476 IPR003691 Putative fluoride ion transporter CrcB Spica_2477 IPR003793 Domain of unknown function DUF190 Spica_2477 IPR011322 Nitrogen regulatory PII-like, alpha/beta Spica_2477 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal Spica_2482 IPR004453 Epoxyqueuosine reductase QueG Spica_2482 IPR013542 Domain of unknown function DUF1730 Spica_2482 IPR016024 Armadillo-type fold Spica_2482 IPR011989 Armadillo-like helical Spica_2482 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_2482 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_2482 IPR004155 PBS lyase HEAT-like repeat Spica_2484 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II Spica_2484 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding Spica_2484 IPR029061 Thiamin diphosphate-binding fold Spica_2484 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain Spica_2484 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_2484 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain Spica_2484 IPR019456 Pyruvate-flavodoxin oxidoreductase, EKR domain Spica_2484 IPR037112 Pyruvate-flavodoxin oxidoreductase, EKR domain superfamily Spica_2484 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II Spica_2484 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_2484 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal Spica_2484 IPR011895 Pyruvate-flavodoxin oxidoreductase Spica_2485 IPR003593 AAA+ ATPase domain Spica_2485 IPR011006 CheY-like superfamily Spica_2485 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2485 IPR025944 Sigma-54 interaction domain, conserved site Spica_2485 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_2485 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_2485 IPR009057 Homeobox-like domain superfamily Spica_2485 IPR002078 RNA polymerase sigma factor 54 interaction domain Spica_2485 IPR001789 Signal transduction response regulator, receiver domain Spica_2485 IPR002197 DNA binding HTH domain, Fis-type Spica_2486 IPR001296 Glycosyl transferase, family 1 Spica_2487 IPR003474 Gluconate transporter Spica_2488 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core Spica_2488 IPR011551 NTP pyrophosphohydrolase MazG Spica_2489 IPR018171 Peptidyl-tRNA hydrolase, conserved site Spica_2489 IPR001328 Peptidyl-tRNA hydrolase Spica_2489 IPR036416 Peptidyl-tRNA hydrolase superfamily Spica_2490 IPR013785 Aldolase-type TIM barrel Spica_2490 IPR017853 Glycoside hydrolase superfamily Spica_2490 IPR011013 Galactose mutarotase-like domain superfamily Spica_2491 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily Spica_2491 IPR038763 DHH phosphoesterase superfamily Spica_2491 IPR000644 CBS domain Spica_2491 IPR001667 DDH domain Spica_2491 IPR038222 DHHA2 domain superfamily Spica_2491 IPR010766 DRTGG Spica_2491 IPR004097 DHHA2 domain Spica_2493 IPR042095 Sulfatase-modifying factor enzyme superfamily Spica_2493 IPR016187 C-type lectin fold Spica_2493 IPR005532 Sulfatase-modifying factor enzyme Spica_2494 IPR001907 ATP-dependent Clp protease proteolytic subunit Spica_2494 IPR029045 ClpP/crotonase-like domain superfamily Spica_2494 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA Spica_2494 IPR033135 ClpP, histidine active site Spica_2495 IPR023753 FAD/NAD(P)-binding domain Spica_2495 IPR017758 Coenzyme A disulphide reductase Spica_2495 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily Spica_2495 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2495 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Spica_2495 IPR023536 Coenzyme A disulphide reductase, staphyolococci Spica_2496 IPR036873 Rhodanese-like domain superfamily Spica_2496 IPR001763 Rhodanese-like domain Spica_2498 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2498 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site Spica_2498 IPR000559 Formate-tetrahydrofolate ligase, FTHFS Spica_2499 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal Spica_2499 IPR001608 Alanine racemase, N-terminal Spica_2499 IPR011079 Alanine racemase, C-terminal Spica_2499 IPR029066 PLP-binding barrel Spica_2499 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site Spica_2499 IPR000821 Alanine racemase Spica_2504 IPR003593 AAA+ ATPase domain Spica_2504 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type Spica_2504 IPR003439 ABC transporter-like Spica_2504 IPR017871 ABC transporter, conserved site Spica_2504 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2505 IPR035906 MetI-like superfamily Spica_2505 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2505 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain Spica_2506 IPR018313 Solute-binding protein family 3, conserved site Spica_2506 IPR001320 Ionotropic glutamate receptor Spica_2506 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spica_2509 IPR029479 Nitroreductase Spica_2509 IPR000415 Nitroreductase-like Spica_2509 IPR033878 Nitroreductase NfsB-like Spica_2511 IPR004268 Peptidoglycan biosynthesis protein MurJ Spica_2512 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily Spica_2512 IPR030395 Glycerophosphodiester phosphodiesterase domain Spica_2516 IPR004772 TrkH potassium transport family Spica_2516 IPR003445 Cation transporter Spica_2517 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_2517 IPR023386 Lysine-tRNA ligase, insertion domain superfamily Spica_2517 IPR002904 Lysine-tRNA ligase Spica_2517 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 Spica_2517 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding Spica_2517 IPR042078 Lysine tRNA ligase, stem contact fold domain Spica_2517 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site Spica_2518 IPR018303 P-type ATPase, phosphorylation site Spica_2518 IPR023299 P-type ATPase, cytoplasmic domain N Spica_2518 IPR023298 P-type ATPase, transmembrane domain superfamily Spica_2518 IPR008250 P-type ATPase, A domain superfamily Spica_2518 IPR036412 HAD-like superfamily Spica_2518 IPR023214 HAD superfamily Spica_2518 IPR036163 Heavy metal-associated domain superfamily Spica_2518 IPR017969 Heavy-metal-associated, conserved site Spica_2518 IPR027256 P-type ATPase, subfamily IB Spica_2518 IPR006121 Heavy metal-associated domain, HMA Spica_2518 IPR001757 P-type ATPase Spica_2519 IPR006122 Heavy metal-associated domain, copper ion-binding Spica_2519 IPR036163 Heavy metal-associated domain superfamily Spica_2519 IPR006121 Heavy metal-associated domain, HMA Spica_2519 IPR017969 Heavy-metal-associated, conserved site Spica_2519 IPR000428 Copper ion binding protein Spica_2521 IPR001633 EAL domain Spica_2521 IPR035919 EAL domain superfamily Spica_2521 IPR029787 Nucleotide cyclase Spica_2521 IPR000160 GGDEF domain Spica_2521 IPR005330 MHYT domain Spica_2528 IPR029510 Aldehyde dehydrogenase, glutamic acid active site Spica_2528 IPR016162 Aldehyde dehydrogenase, N-terminal Spica_2528 IPR016161 Aldehyde/histidinol dehydrogenase Spica_2528 IPR015590 Aldehyde dehydrogenase domain Spica_2528 IPR016163 Aldehyde dehydrogenase, C-terminal Spica_2529 IPR026033 Azaguanine-like transporters Spica_2529 IPR006043 Xanthine/uracil/vitamin C permease Spica_2532 IPR001789 Signal transduction response regulator, receiver domain Spica_2532 IPR011006 CheY-like superfamily Spica_2535 IPR003593 AAA+ ATPase domain Spica_2535 IPR003439 ABC transporter-like Spica_2535 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2535 IPR017871 ABC transporter, conserved site Spica_2535 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal Spica_2536 IPR017871 ABC transporter, conserved site Spica_2536 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal Spica_2536 IPR003439 ABC transporter-like Spica_2536 IPR003593 AAA+ ATPase domain Spica_2536 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2537 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2537 IPR035906 MetI-like superfamily Spica_2537 IPR025966 Oligopeptide transport permease C-like, N-terminal domain Spica_2538 IPR035906 MetI-like superfamily Spica_2538 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2539 IPR039424 Solute-binding protein family 5 Spica_2539 IPR023765 Solute-binding protein family 5, conserved site Spica_2539 IPR000914 Solute-binding protein family 5 domain Spica_2539 IPR030678 Peptide/nickel binding protein, MppA-type Spica_2545 IPR029151 Periplasmic sensor-like domain superfamily Spica_2545 IPR003660 HAMP domain Spica_2545 IPR033479 Double Cache domain 1 Spica_2545 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_2545 IPR000727 Target SNARE coiled-coil homology domain Spica_2549 IPR006130 Aspartate/ornithine carbamoyltransferase Spica_2549 IPR002082 Aspartate carbamoyltransferase Spica_2549 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding Spica_2549 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily Spica_2549 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain Spica_2550 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal Spica_2550 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal Spica_2550 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily Spica_2550 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily Spica_2550 IPR002801 Aspartate transcarbamylase regulatory subunit Spica_2551 IPR011059 Metal-dependent hydrolase, composite domain superfamily Spica_2551 IPR002195 Dihydroorotase, conserved site Spica_2551 IPR006680 Amidohydrolase-related Spica_2551 IPR004722 Dihydroorotase Spica_2551 IPR032466 Metal-dependent hydrolase Spica_2552 IPR011060 Ribulose-phosphate binding barrel Spica_2552 IPR013785 Aldolase-type TIM barrel Spica_2552 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 Spica_2552 IPR001754 Orotidine 5'-phosphate decarboxylase domain Spica_2553 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain Spica_2553 IPR017938 Riboflavin synthase-like beta-barrel Spica_2553 IPR017927 FAD-binding domain, ferredoxin reductase-type Spica_2553 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily Spica_2553 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain Spica_2553 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit Spica_2553 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit Spica_2554 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 Spica_2554 IPR024920 Dihydroorotate dehydrogenase, class 1 Spica_2554 IPR005720 Dihydroorotate dehydrogenase domain Spica_2554 IPR033888 Dihydroorotate dehydrogenase, class 1B Spica_2554 IPR013785 Aldolase-type TIM barrel Spica_2554 IPR001295 Dihydroorotate dehydrogenase, conserved site Spica_2555 IPR029057 Phosphoribosyltransferase-like Spica_2555 IPR000836 Phosphoribosyltransferase domain Spica_2555 IPR023031 Orotate phosphoribosyltransferase Spica_2555 IPR006273 Orotate phosphoribosyltransferase, bacterial Spica_2560 IPR005225 Small GTP-binding protein domain Spica_2560 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2560 IPR032859 GTPase Der, C-terminal KH-domain-like Spica_2560 IPR006073 GTP binding domain Spica_2560 IPR016484 GTP-binding protein EngA Spica_2560 IPR031166 EngA-type guanine nucleotide-binding (G) domain Spica_2560 IPR015946 K homology domain-like, alpha/beta Spica_2561 IPR008279 PEP-utilising enzyme, mobile domain Spica_2561 IPR018274 PEP-utilising enzyme, active site Spica_2561 IPR000121 PEP-utilising enzyme, C-terminal Spica_2561 IPR023151 PEP-utilising enzyme, conserved site Spica_2561 IPR024692 Phosphotransferase system, enzyme I Spica_2561 IPR036618 PtsI, HPr-binding domain superfamily Spica_2561 IPR008731 Phosphotransferase system, enzyme I N-terminal Spica_2561 IPR036637 Phosphohistidine domain superfamily Spica_2561 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily Spica_2561 IPR040442 Pyruvate kinase-like domain superfamily Spica_2561 IPR006318 Phosphotransferase system, enzyme I-like Spica_2565 IPR029787 Nucleotide cyclase Spica_2565 IPR011990 Tetratricopeptide-like helical domain superfamily Spica_2565 IPR019734 Tetratricopeptide repeat Spica_2565 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase Spica_2565 IPR013026 Tetratricopeptide repeat-containing domain Spica_2566 IPR041166 LapB, rubredoxin metal binding domain Spica_2566 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_2566 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_2566 IPR020588 DNA recombination and repair protein RecA-like, ATP-binding domain Spica_2566 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2566 IPR014774 KaiC-like domain Spica_2566 IPR004504 DNA repair protein RadA Spica_2566 IPR003593 AAA+ ATPase domain Spica_2567 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily Spica_2567 IPR035979 RNA-binding domain superfamily Spica_2567 IPR000504 RNA recognition motif domain Spica_2574 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain Spica_2574 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 Spica_2574 IPR002912 ACT domain Spica_2574 IPR036291 NAD(P)-binding domain superfamily Spica_2574 IPR006236 D-3-phosphoglycerate dehydrogenase Spica_2574 IPR029009 Allosteric substrate binding domain superfamily Spica_2574 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site Spica_2574 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Spica_2575 IPR000192 Aminotransferase class V domain Spica_2575 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site Spica_2575 IPR022278 Phosphoserine aminotransferase Spica_2575 IPR015424 Pyridoxal phosphate-dependent transferase Spica_2575 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_2575 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_2576 IPR003781 CoA-binding Spica_2576 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2576 IPR022876 Redox-sensing transcriptional repressor Rex Spica_2576 IPR036291 NAD(P)-binding domain superfamily Spica_2576 IPR036390 Winged helix DNA-binding domain superfamily Spica_2576 IPR009718 Rex DNA-binding, C-terminal domain Spica_2577 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal Spica_2577 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily Spica_2577 IPR011104 HPr kinase/phosphorylase, C-terminal Spica_2577 IPR003755 HPr(Ser) kinase/phosphorylase Spica_2578 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site Spica_2578 IPR035895 HPr-like superfamily Spica_2578 IPR000032 Phosphocarrier protein HPr-like Spica_2578 IPR002114 Phosphotransferase system, HPr serine phosphorylation site Spica_2579 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_2579 IPR003660 HAMP domain Spica_2579 IPR013767 PAS fold Spica_2579 IPR000014 PAS domain Spica_2579 IPR035965 PAS domain superfamily Spica_2579 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_2579 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_2579 IPR005467 Histidine kinase domain Spica_2579 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2579 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator Spica_2579 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2580 IPR011006 CheY-like superfamily Spica_2580 IPR003593 AAA+ ATPase domain Spica_2580 IPR009057 Homeobox-like domain superfamily Spica_2580 IPR002197 DNA binding HTH domain, Fis-type Spica_2580 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2580 IPR025944 Sigma-54 interaction domain, conserved site Spica_2580 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 Spica_2580 IPR002078 RNA polymerase sigma factor 54 interaction domain Spica_2580 IPR001789 Signal transduction response regulator, receiver domain Spica_2580 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_2581 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2581 IPR039418 LexA-like Spica_2581 IPR006200 Transcription regulator LexA Spica_2581 IPR036286 LexA/Signal peptidase-like superfamily Spica_2581 IPR006199 LexA repressor, DNA-binding domain Spica_2581 IPR036390 Winged helix DNA-binding domain superfamily Spica_2581 IPR006197 Peptidase S24, LexA-like Spica_2581 IPR015927 Peptidase S24/S26A/S26B/S26C Spica_2583 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2583 IPR023753 FAD/NAD(P)-binding domain Spica_2584 IPR014119 Heptaprenyl diphosphate synthase component II Spica_2584 IPR033749 Polyprenyl synthetase, conserved site Spica_2584 IPR008949 Isoprenoid synthase domain superfamily Spica_2584 IPR000092 Polyprenyl synthetase Spica_2585 IPR036259 MFS transporter superfamily Spica_2585 IPR003810 Putative manganese efflux pump Spica_2585 IPR022929 Putative manganese efflux pump MntP Spica_2586 IPR002478 PUA domain Spica_2586 IPR015947 PUA-like superfamily Spica_2586 IPR036974 PUA domain superfamily Spica_2586 IPR041532 RlmI, PUA-like domain Spica_2586 IPR023542 rRNA large subunit methyltransferase I Spica_2586 IPR019614 S-adenosylmethionine-dependent methyltransferase Spica_2586 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_2587 IPR025198 Polyphosphate kinase N-terminal domain Spica_2587 IPR003414 Polyphosphate kinase Spica_2587 IPR041108 Polyphosphate kinase, C-terminal domain 1 Spica_2587 IPR024953 Polyphosphate kinase middle domain Spica_2587 IPR025200 Polyphosphate kinase C-terminal domain 2 Spica_2587 IPR036832 Polyphosphate kinase N-terminal domain superfamily Spica_2588 IPR030673 Pyrophosphatase, GppA/Ppx-type Spica_2588 IPR003695 Ppx/GppA phosphatase Spica_2588 IPR022371 Exopolyphosphatase Spica_2589 IPR008928 Six-hairpin glycosidase superfamily Spica_2589 IPR012341 Six-hairpin glycosidase-like superfamily Spica_2589 IPR001661 Glycoside hydrolase, family 37 Spica_2590 IPR017959 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E Spica_2590 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic Spica_2590 IPR018027 Asn/Gln amidotransferase Spica_2590 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like Spica_2590 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site Spica_2590 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 Spica_2590 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit Spica_2590 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain Spica_2590 IPR042114 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 1 Spica_2591 IPR004449 Phosphohistidine phosphatase SixA Spica_2591 IPR029033 Histidine phosphatase superfamily Spica_2591 IPR013078 Histidine phosphatase superfamily, clade-1 Spica_2598 IPR037066 TonB-dependent receptor, plug domain superfamily Spica_2598 IPR039426 Vitamin B12 transporter BtuB-like Spica_2598 IPR012910 TonB-dependent receptor, plug domain Spica_2598 IPR010917 TonB-dependent receptor, conserved site Spica_2598 IPR000531 TonB-dependent receptor-like, beta-barrel Spica_2598 IPR036942 TonB-dependent receptor-like, beta-barrel domain superfamily Spica_2598 IPR010916 TonB box, conserved site Spica_2600 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2600 IPR035906 MetI-like superfamily Spica_2600 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain Spica_2601 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spica_2601 IPR018313 Solute-binding protein family 3, conserved site Spica_2601 IPR001320 Ionotropic glutamate receptor Spica_2603 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2603 IPR039420 Transcriptional regulatory protein WalR-like Spica_2603 IPR016032 Signal transduction response regulator, C-terminal effector Spica_2603 IPR001789 Signal transduction response regulator, receiver domain Spica_2603 IPR001867 OmpR/PhoB-type DNA-binding domain Spica_2603 IPR011006 CheY-like superfamily Spica_2604 IPR005467 Histidine kinase domain Spica_2604 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2604 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2604 IPR003660 HAMP domain Spica_2604 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_2604 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_2604 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_2605 IPR003439 ABC transporter-like Spica_2605 IPR003593 AAA+ ATPase domain Spica_2605 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2605 IPR005978 Nodulation ABC transporter, NodI Spica_2605 IPR015851 ABC transporter, NodI Spica_2605 IPR017871 ABC transporter, conserved site Spica_2610 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily Spica_2610 IPR035979 RNA-binding domain superfamily Spica_2610 IPR000504 RNA recognition motif domain Spica_2611 IPR003660 HAMP domain Spica_2611 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain Spica_2612 IPR001789 Signal transduction response regulator, receiver domain Spica_2612 IPR011006 CheY-like superfamily Spica_2612 IPR037522 HD-GYP domain Spica_2612 IPR003607 HD/PDEase domain Spica_2614 IPR003385 Glycoside hydrolase, family 77 Spica_2614 IPR017853 Glycoside hydrolase superfamily Spica_2617 IPR037158 Threonine synthase, N-terminal domain superfamily Spica_2617 IPR001926 Pyridoxal-phosphate dependent enzyme Spica_2617 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site Spica_2617 IPR029144 Threonine synthase, N-terminal Spica_2617 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spica_2617 IPR004450 Threonine synthase-like Spica_2618 IPR018313 Solute-binding protein family 3, conserved site Spica_2618 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF Spica_2618 IPR001320 Ionotropic glutamate receptor Spica_2619 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain Spica_2619 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2619 IPR035906 MetI-like superfamily Spica_2620 IPR017871 ABC transporter, conserved site Spica_2620 IPR003439 ABC transporter-like Spica_2620 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type Spica_2620 IPR003593 AAA+ ATPase domain Spica_2620 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2621 IPR036196 Phosphotyrosine protein phosphatase I superfamily Spica_2621 IPR023485 Phosphotyrosine protein phosphatase I Spica_2621 IPR014064 Arsenate reductase ArsC Spica_2622 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2622 IPR001845 HTH ArsR-type DNA-binding domain Spica_2622 IPR011991 ArsR-like helix-turn-helix domain Spica_2622 IPR036390 Winged helix DNA-binding domain superfamily Spica_2625 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating Spica_2625 IPR013328 6-phosphogluconate dehydrogenase, domain 2 Spica_2625 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily Spica_2625 IPR006114 6-phosphogluconate dehydrogenase, C-terminal Spica_2625 IPR006183 6-phosphogluconate dehydrogenase Spica_2625 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding Spica_2625 IPR006184 6-phosphogluconate-binding site Spica_2625 IPR036291 NAD(P)-binding domain superfamily Spica_2626 IPR023588 Transcription regulator HTH, PurR Spica_2626 IPR000843 LacI-type HTH domain Spica_2626 IPR010982 Lambda repressor-like, DNA-binding domain superfamily Spica_2626 IPR028082 Periplasmic binding protein-like I Spica_2627 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_2627 IPR016181 Acyl-CoA N-acyltransferase Spica_2627 IPR025777 GMP synthetase ATP pyrophosphatase domain Spica_2627 IPR001674 GMP synthase, C-terminal Spica_2627 IPR017926 Glutamine amidotransferase Spica_2627 IPR011257 DNA glycosylase Spica_2627 IPR029062 Class I glutamine amidotransferase-like Spica_2627 IPR005019 Methyladenine glycosylase Spica_2627 IPR000182 GNAT domain Spica_2628 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit Spica_2628 IPR004681 TRAP transporter large membrane protein DctM Spica_2630 IPR004682 TRAP transporter solute receptor, DctP family Spica_2630 IPR018389 TRAP transporter solute receptor DctP/TeaA Spica_2630 IPR038404 TRAP transporter solute receptor DctP superfamily Spica_2631 IPR011006 CheY-like superfamily Spica_2631 IPR001789 Signal transduction response regulator, receiver domain Spica_2631 IPR018060 DNA binding HTH domain, AraC-type Spica_2631 IPR009057 Homeobox-like domain superfamily Spica_2632 IPR010559 Signal transduction histidine kinase, internal region Spica_2632 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2632 IPR003018 GAF domain Spica_2632 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region Spica_2633 IPR000160 GGDEF domain Spica_2633 IPR029016 GAF-like domain superfamily Spica_2633 IPR029787 Nucleotide cyclase Spica_2634 IPR038765 Papain-like cysteine peptidase superfamily Spica_2634 IPR000064 Endopeptidase, NLPC/P60 domain Spica_2639 IPR002505 Phosphate acetyl/butaryl transferase Spica_2639 IPR014079 Phosphate butyryltransferase Spica_2639 IPR012147 Phosphate acetyl/butyryltransferase Spica_2640 IPR011245 Butyrate kinase Spica_2640 IPR023865 Aliphatic acid kinase, short-chain, conserved site Spica_2640 IPR000890 Aliphatic acid kinase, short-chain Spica_2643 IPR011650 Peptidase M20, dimerisation domain Spica_2643 IPR010161 Peptidase M20B, tripeptide aminopeptidase Spica_2643 IPR036264 Bacterial exopeptidase dimerisation domain Spica_2643 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site Spica_2643 IPR002933 Peptidase M20 Spica_2648 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2648 IPR003439 ABC transporter-like Spica_2648 IPR003593 AAA+ ATPase domain Spica_2650 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2650 IPR028348 FAD dependent protein Spica_2651 IPR011004 Trimeric LpxA-like superfamily Spica_2651 IPR032533 Protein of unknown function DUF4954 Spica_2652 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Spica_2653 IPR013335 Trp repressor, bacterial Spica_2653 IPR010921 Trp repressor/replication initiator Spica_2653 IPR038116 TrpR-like superfamily Spica_2653 IPR000831 Trp repressor Spica_2654 IPR032524 ABC transporter Uup, C-terminal Spica_2654 IPR003593 AAA+ ATPase domain Spica_2654 IPR017871 ABC transporter, conserved site Spica_2654 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2654 IPR032781 ABC-transporter extension domain Spica_2654 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily Spica_2654 IPR003439 ABC transporter-like Spica_2655 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2655 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_2655 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_2655 IPR015387 LuxQ, periplasmic Spica_2655 IPR029151 Periplasmic sensor-like domain superfamily Spica_2655 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_2655 IPR001789 Signal transduction response regulator, receiver domain Spica_2655 IPR011006 CheY-like superfamily Spica_2655 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2655 IPR005467 Histidine kinase domain Spica_2658 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2658 IPR015861 ABC transporter, ribose import, RbsA Spica_2658 IPR003593 AAA+ ATPase domain Spica_2658 IPR003439 ABC transporter-like Spica_2658 IPR017871 ABC transporter, conserved site Spica_2659 IPR028082 Periplasmic binding protein-like I Spica_2659 IPR003760 ABC transporter substrate-binding protein PnrA-like Spica_2664 IPR003477 mRNA interferase PemK-like Spica_2664 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor Spica_2668 IPR002942 RNA-binding S4 domain Spica_2668 IPR006145 Pseudouridine synthase, RsuA/RluA Spica_2668 IPR006225 Pseudouridine synthase, RluC/RluD Spica_2668 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site Spica_2668 IPR020103 Pseudouridine synthase, catalytic domain superfamily Spica_2670 IPR027057 CAAX prenyl protease 1 Spica_2670 IPR001915 Peptidase M48 Spica_2670 IPR032456 CAAX prenyl protease 1, N-terminal Spica_2671 IPR029035 DHS-like NAD/FAD-binding domain superfamily Spica_2671 IPR029061 Thiamin diphosphate-binding fold Spica_2671 IPR039368 Acetolactate synthase large subunit, TPP binding domain Spica_2671 IPR012846 Acetolactate synthase, large subunit, biosynthetic Spica_2671 IPR012000 Thiamine pyrophosphate enzyme, central domain Spica_2671 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain Spica_2671 IPR000399 TPP-binding enzyme, conserved site Spica_2671 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding Spica_2673 IPR024084 Isopropylmalate dehydrogenase-like domain Spica_2673 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site Spica_2673 IPR004429 Isopropylmalate dehydrogenase Spica_2674 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily Spica_2674 IPR013785 Aldolase-type TIM barrel Spica_2674 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain Spica_2674 IPR005675 Citramalate synthase Spica_2674 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site Spica_2674 IPR000891 Pyruvate carboxyltransferase Spica_2676 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily Spica_2676 IPR013023 Ketol-acid reductoisomerase Spica_2676 IPR000506 Ketol-acid reductoisomerase, C-terminal Spica_2676 IPR013116 Ketol-acid reductoisomerase, N-terminal Spica_2676 IPR014359 Ketol-acid reductoisomerase, prokaryotic Spica_2676 IPR036291 NAD(P)-binding domain superfamily Spica_2677 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal Spica_2677 IPR004789 Acetolactate synthase, small subunit Spica_2677 IPR019455 Acetolactate synthase, small subunit, C-terminal Spica_2677 IPR002912 ACT domain Spica_2677 IPR039557 AHAS, ACT domain Spica_2678 IPR013785 Aldolase-type TIM barrel Spica_2678 IPR041071 DAHP synthase ferredoxin-like domain Spica_2678 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 Spica_2678 IPR006218 DAHP synthetase I/KDSA Spica_2679 IPR006357 HAD-superfamily hydrolase, subfamily IIA Spica_2679 IPR023214 HAD superfamily Spica_2679 IPR036412 HAD-like superfamily Spica_2682 IPR010412 Protein of unknown function DUF1007 Spica_2683 IPR011541 Nickel/cobalt transporter, high-affinity Spica_2686 IPR004794 Riboflavin biosynthesis protein RibD Spica_2686 IPR024072 Dihydrofolate reductase-like domain superfamily Spica_2686 IPR016193 Cytidine deaminase-like Spica_2686 IPR011549 Riboflavin-specific deaminase, C-terminal Spica_2686 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal Spica_2686 IPR016192 APOBEC/CMP deaminase, zinc-binding Spica_2686 IPR002125 Cytidine and deoxycytidylate deaminase domain Spica_2687 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site Spica_2687 IPR004404 Dihydroxy-acid dehydratase Spica_2687 IPR037237 IlvD/EDD, N-terminal domain Spica_2687 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase Spica_2687 IPR042096 Dihydroxy-acid dehydratase, C-terminal Spica_2688 IPR033941 3-Isopropylmalate dehydratase, catalytic domain Spica_2688 IPR036008 Aconitase, iron-sulfur domain Spica_2688 IPR018136 Aconitase family, 4Fe-4S cluster binding site Spica_2688 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 Spica_2688 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain Spica_2688 IPR004430 3-isopropylmalate dehydratase, large subunit Spica_2689 IPR004431 3-isopropylmalate dehydratase, small subunit Spica_2689 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain Spica_2689 IPR033940 3-isopropylmalate dehydratase, swivel domain Spica_2689 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel Spica_2690 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding Spica_2690 IPR012000 Thiamine pyrophosphate enzyme, central domain Spica_2690 IPR029061 Thiamin diphosphate-binding fold Spica_2690 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain Spica_2690 IPR029035 DHS-like NAD/FAD-binding domain superfamily Spica_2690 IPR012846 Acetolactate synthase, large subunit, biosynthetic Spica_2690 IPR039368 Acetolactate synthase large subunit, TPP binding domain Spica_2691 IPR039557 AHAS, ACT domain Spica_2691 IPR004789 Acetolactate synthase, small subunit Spica_2691 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal Spica_2691 IPR019455 Acetolactate synthase, small subunit, C-terminal Spica_2691 IPR002912 ACT domain Spica_2692 IPR036259 MFS transporter superfamily Spica_2692 IPR020846 Major facilitator superfamily domain Spica_2692 IPR011701 Major facilitator superfamily Spica_2692 IPR005829 Sugar transporter, conserved site Spica_2695 IPR014001 Helicase superfamily 1/2, ATP-binding domain Spica_2695 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2695 IPR021810 Protein of unknown function DUF3387 Spica_2695 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal Spica_2695 IPR004473 Restriction endonuclease, type I, HsdR Spica_2695 IPR040980 SWI2/SNF2 ATPase Spica_2697 IPR000055 Restriction endonuclease, type I, HsdS Spica_2702 IPR003356 DNA methylase, adenine-specific Spica_2702 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily Spica_2702 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_2704 IPR031807 HicB-like antitoxin of toxin-antitoxin system Spica_2704 IPR035069 TTHA1013/TTHA0281-like Spica_2705 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2705 IPR041328 ResE, histidine kinase sensor domain Spica_2705 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_2705 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_2705 IPR005467 Histidine kinase domain Spica_2705 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2705 IPR003660 HAMP domain Spica_2705 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_2706 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 Spica_2706 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily Spica_2706 IPR005145 Putative GTP-binding controlling metal-binding domain Spica_2706 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily Spica_2706 IPR006070 YrdC-like domain Spica_2708 IPR004488 Magnesium/cobalt transport protein CorA Spica_2708 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB Spica_2709 IPR001701 Glycoside hydrolase family 9 Spica_2709 IPR014756 Immunoglobulin E-set Spica_2709 IPR013098 Immunoglobulin I-set Spica_2709 IPR003599 Immunoglobulin subtype Spica_2709 IPR036179 Immunoglobulin-like domain superfamily Spica_2709 IPR008928 Six-hairpin glycosidase superfamily Spica_2709 IPR008979 Galactose-binding-like domain superfamily Spica_2709 IPR004197 Cellulase, Ig-like domain Spica_2709 IPR012341 Six-hairpin glycosidase-like superfamily Spica_2709 IPR013783 Immunoglobulin-like fold Spica_2709 IPR007110 Immunoglobulin-like domain Spica_2709 IPR003305 Carbohydrate-binding, CenC-like Spica_2709 IPR018221 Glycoside hydrolase family 9, His active site Spica_2709 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites Spica_2712 IPR036412 HAD-like superfamily Spica_2712 IPR023943 Enolase-phosphatase E1 Spica_2712 IPR041492 Haloacid dehalogenase-like hydrolase Spica_2712 IPR006439 HAD hydrolase, subfamily IA Spica_2712 IPR023214 HAD superfamily Spica_2714 IPR015413 Methionyl/Leucyl tRNA synthetase Spica_2714 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold Spica_2714 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding Spica_2714 IPR002300 Aminoacyl-tRNA synthetase, class Ia Spica_2714 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding Spica_2714 IPR002302 Leucine-tRNA ligase Spica_2714 IPR025709 Leucyl-tRNA synthetase, editing domain Spica_2714 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain Spica_2714 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site Spica_2715 IPR013096 Cupin 2, conserved barrel Spica_2715 IPR011051 RmlC-like cupin domain superfamily Spica_2715 IPR014710 RmlC-like jelly roll fold Spica_2717 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Spica_2718 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase Spica_2718 IPR015424 Pyridoxal phosphate-dependent transferase Spica_2718 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 Spica_2718 IPR015421 Pyridoxal phosphate-dependent transferase, major domain Spica_2718 IPR023603 Threonine aldolase Spica_2719 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal Spica_2719 IPR000587 Creatinase, N-terminal Spica_2719 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site Spica_2719 IPR001714 Peptidase M24, methionine aminopeptidase Spica_2719 IPR036005 Creatinase/aminopeptidase-like Spica_2719 IPR000994 Peptidase M24 Spica_2722 IPR007419 BFD-like [2Fe-2S]-binding domain Spica_2722 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2722 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B Spica_2722 IPR023753 FAD/NAD(P)-binding domain Spica_2722 IPR041854 BFD-like [2Fe-2S]-binding domain superfamily Spica_2723 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase Spica_2723 IPR036188 FAD/NAD(P)-binding domain superfamily Spica_2723 IPR006076 FAD dependent oxidoreductase Spica_2723 IPR031656 Alpha-glycerophosphate oxidase, C-terminal Spica_2723 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily Spica_2726 IPR013976 Metal-dependent hydrolase HDOD Spica_2729 IPR035901 GIY-YIG endonuclease superfamily Spica_2729 IPR010994 RuvA domain 2-like Spica_2729 IPR001943 UVR domain Spica_2729 IPR001162 UvrC family homology region Spica_2729 IPR004791 UvrABC system, subunit C Spica_2729 IPR036876 UVR domain superfamily Spica_2729 IPR000305 GIY-YIG endonuclease Spica_2729 IPR038476 UvrC homology region 2 superfamily Spica_2731 IPR007046 RNA polymerase sigma factor 54, core-binding domain Spica_2731 IPR000394 RNA polymerase sigma factor 54 Spica_2731 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily Spica_2731 IPR007634 RNA polymerase sigma factor 54, DNA-binding Spica_2733 IPR003709 Peptidase M15B Spica_2733 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Spica_2737 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2737 IPR026008 Uridine kinase Spica_2737 IPR000764 Uridine kinase-like Spica_2737 IPR006083 Phosphoribulokinase/uridine kinase Spica_2738 IPR000175 Sodium:neurotransmitter symporter Spica_2738 IPR037272 Sodium:neurotransmitter symporter superfamily Spica_2739 IPR012724 Chaperone DnaJ Spica_2739 IPR002939 Chaperone DnaJ, C-terminal Spica_2739 IPR001623 DnaJ domain Spica_2739 IPR018253 DnaJ domain, conserved site Spica_2739 IPR036869 Chaperone J-domain superfamily Spica_2739 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily Spica_2739 IPR001305 Heat shock protein DnaJ, cysteine-rich domain Spica_2739 IPR008971 HSP40/DnaJ peptide-binding Spica_2740 IPR012725 Chaperone DnaK Spica_2740 IPR013126 Heat shock protein 70 family Spica_2740 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Spica_2740 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Spica_2740 IPR018181 Heat shock protein 70, conserved site Spica_2741 IPR000740 GrpE nucleotide exchange factor Spica_2741 IPR013805 GrpE nucleotide exchange factor, coiled-coil Spica_2741 IPR009012 GrpE nucleotide exchange factor, head Spica_2743 IPR003824 Undecaprenyl-diphosphatase UppP Spica_2744 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F Spica_2744 IPR036986 RNA-binding S4 domain superfamily Spica_2744 IPR002942 RNA-binding S4 domain Spica_2744 IPR042092 Pseudouridine synthase, RsuA/RluB/E/F, catalytic domain Spica_2744 IPR020103 Pseudouridine synthase, catalytic domain superfamily Spica_2744 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site Spica_2744 IPR006145 Pseudouridine synthase, RsuA/RluA Spica_2745 IPR036237 Xylose isomerase-like superfamily Spica_2745 IPR001998 Xylose isomerase Spica_2745 IPR013452 Xylose isomerase, bacterial-type Spica_2746 IPR018484 Carbohydrate kinase, FGGY, N-terminal Spica_2746 IPR018483 Carbohydrate kinase, FGGY, conserved site Spica_2746 IPR006000 Xylulokinase Spica_2746 IPR018485 Carbohydrate kinase, FGGY, C-terminal Spica_2746 IPR000577 Carbohydrate kinase, FGGY Spica_2747 IPR003313 AraC-type arabinose-binding/dimerisation domain Spica_2747 IPR037923 Transcription regulator HTH-like Spica_2747 IPR009057 Homeobox-like domain superfamily Spica_2747 IPR018060 DNA binding HTH domain, AraC-type Spica_2747 IPR018062 HTH domain AraC-type, conserved site Spica_2747 IPR020449 Transcription regulator HTH, AraC- type Spica_2748 IPR001867 OmpR/PhoB-type DNA-binding domain Spica_2748 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2748 IPR016032 Signal transduction response regulator, C-terminal effector Spica_2748 IPR039420 Transcriptional regulatory protein WalR-like Spica_2748 IPR011006 CheY-like superfamily Spica_2748 IPR001789 Signal transduction response regulator, receiver domain Spica_2749 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2749 IPR005467 Histidine kinase domain Spica_2749 IPR000700 PAS-associated, C-terminal Spica_2749 IPR035965 PAS domain superfamily Spica_2749 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2749 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_2749 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain Spica_2749 IPR000014 PAS domain Spica_2751 IPR017871 ABC transporter, conserved site Spica_2751 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2751 IPR030296 Probable ABC transporter ATP-binding protein MlaF/Mkl Spica_2751 IPR003439 ABC transporter-like Spica_2751 IPR003593 AAA+ ATPase domain Spica_2752 IPR003453 ABC transport permease subunit MlaE, Proteobacteria Spica_2752 IPR030802 ABC transporter permease MalE Spica_2755 IPR003439 ABC transporter-like Spica_2755 IPR017871 ABC transporter, conserved site Spica_2755 IPR003593 AAA+ ATPase domain Spica_2755 IPR005286 Cell division protein FtsE, ATP-binding Spica_2755 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2758 IPR005235 Metallophosphoesterase, YmdB-like Spica_2758 IPR029052 Metallo-dependent phosphatase-like Spica_2759 IPR003607 HD/PDEase domain Spica_2759 IPR036612 K Homology domain, type 1 superfamily Spica_2759 IPR004088 K Homology domain, type 1 Spica_2759 IPR006675 HDIG domain Spica_2759 IPR017705 Ribonuclease Y Spica_2759 IPR022711 Ribonuclease Y, N-terminal Spica_2759 IPR004087 K Homology domain Spica_2759 IPR006674 HD domain Spica_2760 IPR003439 ABC transporter-like Spica_2760 IPR003593 AAA+ ATPase domain Spica_2760 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2760 IPR030921 LPS export ABC transporter, ATP-binding protein LptB Spica_2760 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal Spica_2760 IPR017871 ABC transporter, conserved site Spica_2763 IPR033828 CTP synthase GATase domain Spica_2763 IPR004468 CTP synthase Spica_2763 IPR017456 CTP synthase, N-terminal Spica_2763 IPR017926 Glutamine amidotransferase Spica_2763 IPR029062 Class I glutamine amidotransferase-like Spica_2763 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2765 IPR026024 Chemotaxis protein methyltransferase CheR Spica_2765 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal Spica_2765 IPR000780 MCP methyltransferase, CheR-type Spica_2765 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal Spica_2765 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily Spica_2765 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase Spica_2766 IPR008248 Protein-glutamate methylesterase/protein-glutamine glutaminase, CheB type Spica_2766 IPR035909 Methylesterase CheB, C-terminal Spica_2766 IPR011006 CheY-like superfamily Spica_2766 IPR001789 Signal transduction response regulator, receiver domain Spica_2766 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase Spica_2768 IPR011812 Biosynthetic peptidoglycan transglycosylase Spica_2768 IPR001264 Glycosyl transferase, family 51 Spica_2768 IPR023346 Lysozyme-like domain superfamily Spica_2768 IPR036950 Penicillin binding protein transglycosylase domain Spica_2770 IPR029052 Metallo-dependent phosphatase-like Spica_2770 IPR005235 Metallophosphoesterase, YmdB-like Spica_2773 IPR013352 Iron hydrogenase, subset Spica_2773 IPR036991 Iron hydrogenase, small subunit superfamily Spica_2773 IPR003149 Iron hydrogenase, small subunit Spica_2773 IPR004108 Iron hydrogenase, large subunit, C-terminal Spica_2773 IPR036010 2Fe-2S ferredoxin-like superfamily Spica_2773 IPR009016 Iron hydrogenase Spica_2773 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_2773 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding Spica_2773 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_2773 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain Spica_2774 IPR037225 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily Spica_2774 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain Spica_2774 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Spica_2774 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site Spica_2774 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain Spica_2774 IPR037207 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily Spica_2774 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site Spica_2776 IPR003660 HAMP domain Spica_2776 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2776 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2776 IPR005467 Histidine kinase domain Spica_2776 IPR017232 Signal transduction histidine kinase, nitrogen fixation and metabolism regulator Spica_2776 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_2777 IPR041921 NADH-quinone oxidoreductase subunit E, N-terminal Spica_2777 IPR036249 Thioredoxin-like superfamily Spica_2777 IPR042128 NuoE domain Spica_2777 IPR002023 NADH-quinone oxidoreductase subunit E-like Spica_2777 IPR028431 NADP-reducing hydrogenase subunit HndA Spica_2779 IPR020459 AMP-binding Spica_2779 IPR020845 AMP-binding, conserved site Spica_2779 IPR025110 AMP-binding enzyme, C-terminal domain Spica_2779 IPR042099 AMP-dependent synthetase-like superfamily Spica_2779 IPR000873 AMP-dependent synthetase/ligase Spica_2783 IPR013785 Aldolase-type TIM barrel Spica_2783 IPR000644 CBS domain Spica_2783 IPR005990 Inosine-5'-monophosphate dehydrogenase Spica_2783 IPR015875 IMP dehydrogenase / GMP reductase, conserved site Spica_2783 IPR001093 IMP dehydrogenase/GMP reductase Spica_2784 IPR023214 HAD superfamily Spica_2784 IPR036412 HAD-like superfamily Spica_2784 IPR006379 HAD-superfamily hydrolase, subfamily IIB Spica_2784 IPR000150 Cof family Spica_2786 IPR001451 Hexapeptide repeat Spica_2786 IPR011004 Trimeric LpxA-like superfamily Spica_2786 IPR023446 Carnitine operon protein CaiE Spica_2787 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2787 IPR025669 AAA domain Spica_2788 IPR036086 ParB/Sulfiredoxin superfamily Spica_2788 IPR003115 ParB/Sulfiredoxin Spica_2788 IPR004437 ParB/RepB/Spo0J partition protein Spica_2788 IPR041468 ParB/Spo0J, HTH domain Spica_2789 IPR009057 Homeobox-like domain superfamily Spica_2789 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 Spica_2789 IPR002197 DNA binding HTH domain, Fis-type Spica_2789 IPR002078 RNA polymerase sigma factor 54 interaction domain Spica_2789 IPR025944 Sigma-54 interaction domain, conserved site Spica_2789 IPR010114 DNA-binding transcriptional regulator NtrC Spica_2789 IPR001789 Signal transduction response regulator, receiver domain Spica_2789 IPR003593 AAA+ ATPase domain Spica_2789 IPR011006 CheY-like superfamily Spica_2789 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2790 IPR013123 RNA 2-O ribose methyltransferase, substrate binding Spica_2790 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB Spica_2790 IPR004441 RNA methyltransferase TrmH family Spica_2790 IPR001537 tRNA/rRNA methyltransferase, SpoU type Spica_2790 IPR029028 Alpha/beta knot methyltransferases Spica_2790 IPR029064 50S ribosomal protein L30e-like Spica_2790 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spica_2792 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme Spica_2792 IPR023026 Tryptophan synthase beta chain/beta chain-like Spica_2792 IPR001926 Pyridoxal-phosphate dependent enzyme Spica_2792 IPR006316 Tryptophan synthase, beta chain-like Spica_2792 IPR006654 Tryptophan synthase, beta chain Spica_2792 IPR006653 Tryptophan synthase, beta chain, conserved site Spica_2793 IPR029044 Nucleotide-diphospho-sugar transferases Spica_2800 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 Spica_2800 IPR003439 ABC transporter-like Spica_2800 IPR017871 ABC transporter, conserved site Spica_2800 IPR015856 ABC transporter, CbiO/EcfA subunit Spica_2800 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2800 IPR003593 AAA+ ATPase domain Spica_2801 IPR001851 ABC transporter, permease Spica_2803 IPR036291 NAD(P)-binding domain superfamily Spica_2803 IPR001891 Malic oxidoreductase Spica_2803 IPR012302 Malic enzyme, NAD-binding Spica_2803 IPR037062 Malic enzyme, N-terminal domain superfamily Spica_2803 IPR012301 Malic enzyme, N-terminal domain Spica_2803 IPR015884 Malic enzyme, conserved site Spica_2806 IPR013014 Phosphotransferase system, EIIC component, type 2 Spica_2806 IPR004703 Phosphotransferase system, sugar-specific permease component Spica_2806 IPR013853 Galactitol permease IIC component Spica_2807 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain Spica_2807 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) Spica_2807 IPR006195 Aminoacyl-tRNA synthetase, class II Spica_2807 IPR004154 Anticodon-binding Spica_2807 IPR036621 Anticodon-binding domain superfamily Spica_2807 IPR002316 Proline-tRNA ligase, class IIa Spica_2807 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type Spica_2807 IPR033730 Prokaryote proline-tRNA ligase core domain Spica_2807 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily Spica_2807 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 Spica_2809 IPR000811 Glycosyl transferase, family 35 Spica_2809 IPR011833 Glycogen/starch/alpha-glucan phosphorylase Spica_2809 IPR035090 Phosphorylase pyridoxal-phosphate attachment site Spica_2811 IPR002575 Aminoglycoside phosphotransferase Spica_2811 IPR011009 Protein kinase-like domain superfamily Spica_2811 IPR032882 SrkA/RdoA protein kinase Spica_2812 IPR010136 N-acetyl-gamma-glutamyl-phosphate reductase, type 2 Spica_2812 IPR036291 NAD(P)-binding domain superfamily Spica_2812 IPR000534 Semialdehyde dehydrogenase, NAD-binding Spica_2813 IPR001851 ABC transporter, permease Spica_2814 IPR003593 AAA+ ATPase domain Spica_2814 IPR003439 ABC transporter-like Spica_2814 IPR017871 ABC transporter, conserved site Spica_2814 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2815 IPR025997 Periplasmic binding protein Spica_2815 IPR028082 Periplasmic binding protein-like I Spica_2816 IPR037171 NagB/RpiA transferase-like Spica_2816 IPR018356 Transcription regulator, HTH DeoR-type, conserved site Spica_2816 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2816 IPR036390 Winged helix DNA-binding domain superfamily Spica_2816 IPR001034 DeoR-type HTH domain Spica_2816 IPR014036 DeoR C-terminal sensor domain Spica_2817 IPR003439 ABC transporter-like Spica_2817 IPR017871 ABC transporter, conserved site Spica_2817 IPR015861 ABC transporter, ribose import, RbsA Spica_2817 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2817 IPR003593 AAA+ ATPase domain Spica_2818 IPR036409 Class II aldolase/adducin N-terminal domain superfamily Spica_2818 IPR004661 L-ribulose-5-phosphate 4-epimerase Spica_2818 IPR001303 Class II aldolase/adducin N-terminal Spica_2819 IPR003762 L-arabinose isomerase Spica_2819 IPR009015 L-fucose isomerase, N-terminal/central domain superfamily Spica_2819 IPR004216 L-fucose/L-arabinose isomerase, C-terminal Spica_2819 IPR038583 L-arabinose isomerase, N-terminal domain superfamily Spica_2819 IPR024664 L-arabinose isomerase, C-terminal Spica_2821 IPR002528 Multi antimicrobial extrusion protein Spica_2826 IPR013123 RNA 2-O ribose methyltransferase, substrate binding Spica_2826 IPR029028 Alpha/beta knot methyltransferases Spica_2826 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal Spica_2826 IPR024915 23S rRNA (guanosine-2-O-)-methyltransferase RlmB Spica_2826 IPR001537 tRNA/rRNA methyltransferase, SpoU type Spica_2826 IPR004441 RNA methyltransferase TrmH family Spica_2826 IPR029064 50S ribosomal protein L30e-like Spica_2827 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like Spica_2827 IPR022712 Beta-Casp domain Spica_2827 IPR001279 Metallo-beta-lactamase Spica_2827 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain Spica_2828 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily Spica_2828 IPR013328 6-phosphogluconate dehydrogenase, domain 2 Spica_2828 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding Spica_2828 IPR015815 3-hydroxyisobutyrate dehydrogenase-related Spica_2828 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain Spica_2828 IPR036291 NAD(P)-binding domain superfamily Spica_2828 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site Spica_2831 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain Spica_2831 IPR023514 Glyoxylate/hydroxypyruvate reductase A Spica_2831 IPR036291 NAD(P)-binding domain superfamily Spica_2832 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Spica_2832 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily Spica_2832 IPR004223 Vitamin B12-dependent methionine synthase, activation domain Spica_2832 IPR000489 Pterin-binding domain Spica_2832 IPR036594 Methionine synthase domain Spica_2832 IPR011822 Cobalamin-dependent methionine synthase Spica_2832 IPR036589 Homocysteine-binding domain superfamily Spica_2832 IPR003726 Homocysteine-binding domain Spica_2832 IPR011005 Dihydropteroate synthase-like Spica_2832 IPR036724 Cobalamin-binding domain superfamily Spica_2832 IPR006158 Cobalamin (vitamin B12)-binding domain Spica_2832 IPR033706 Methionine synthase, B12-binding domain Spica_2836 IPR023214 HAD superfamily Spica_2836 IPR036412 HAD-like superfamily Spica_2836 IPR010708 5'(3')-deoxyribonucleotidase Spica_2837 IPR003593 AAA+ ATPase domain Spica_2837 IPR003439 ABC transporter-like Spica_2837 IPR017871 ABC transporter, conserved site Spica_2837 IPR015863 ABC transporter, hemin import, HmuV Spica_2837 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2839 IPR001789 Signal transduction response regulator, receiver domain Spica_2839 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2839 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily Spica_2839 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2839 IPR004358 Signal transduction histidine kinase-related protein, C-terminal Spica_2839 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain Spica_2839 IPR005467 Histidine kinase domain Spica_2840 IPR013783 Immunoglobulin-like fold Spica_2840 IPR017853 Glycoside hydrolase superfamily Spica_2840 IPR011837 Glycogen debranching enzyme, GlgX type Spica_2840 IPR013780 Glycosyl hydrolase, all-beta Spica_2840 IPR004193 Glycoside hydrolase, family 13, N-terminal Spica_2840 IPR014756 Immunoglobulin E-set Spica_2840 IPR006047 Glycosyl hydrolase, family 13, catalytic domain Spica_2843 IPR036291 NAD(P)-binding domain superfamily Spica_2843 IPR006037 Regulator of K+ conductance, C-terminal Spica_2843 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily Spica_2843 IPR003148 Regulator of K+ conductance, N-terminal Spica_2844 IPR003445 Cation transporter Spica_2844 IPR004772 TrkH potassium transport family Spica_2846 IPR035906 MetI-like superfamily Spica_2846 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2847 IPR035906 MetI-like superfamily Spica_2847 IPR000515 ABC transporter type 1, transmembrane domain MetI-like Spica_2848 IPR006059 Bacterial extracellular solute-binding protein Spica_2849 IPR036388 Winged helix-like DNA-binding domain superfamily Spica_2849 IPR009057 Homeobox-like domain superfamily Spica_2849 IPR000281 Helix-turn-helix protein RpiR Spica_2849 IPR035472 RpiR-like, SIS domain Spica_2849 IPR001347 Sugar isomerase (SIS) Spica_2850 IPR013149 Alcohol dehydrogenase, C-terminal Spica_2850 IPR013154 Alcohol dehydrogenase, N-terminal Spica_2850 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site Spica_2850 IPR011032 GroES-like superfamily Spica_2850 IPR020843 Polyketide synthase, enoylreductase domain Spica_2850 IPR036291 NAD(P)-binding domain superfamily Spica_2851 IPR004104 Oxidoreductase, C-terminal Spica_2851 IPR036291 NAD(P)-binding domain superfamily Spica_2851 IPR000683 Oxidoreductase, N-terminal Spica_2852 IPR011703 ATPase, AAA-3 Spica_2852 IPR027417 P-loop containing nucleoside triphosphate hydrolase Spica_2852 IPR041628 ChlI/MoxR, AAA lid domain Spica_2855 IPR010652 Domain of unknown function DUF1232 Spica_2857 IPR042099 AMP-dependent synthetase-like superfamily Spica_2857 IPR000873 AMP-dependent synthetase/ligase Spica_2857 IPR020845 AMP-binding, conserved site Spica_2858 IPR022629 S-adenosylmethionine synthetase, central domain Spica_2858 IPR002133 S-adenosylmethionine synthetase Spica_2858 IPR022628 S-adenosylmethionine synthetase, N-terminal Spica_2858 IPR022630 S-adenosylmethionine synthetase, C-terminal Spica_2858 IPR022631 S-adenosylmethionine synthetase, conserved site Spica_2858 IPR022636 S-adenosylmethionine synthetase superfamily Spica_2859 IPR005139 Peptide chain release factor Spica_2859 IPR000352 Peptide chain release factor class I Spica_2859 IPR004373 Peptide chain release factor 1 Spica_2862 IPR000064 Endopeptidase, NLPC/P60 domain Spica_2862 IPR038765 Papain-like cysteine peptidase superfamily Spica_2868 IPR005743 DNA gyrase, subunit A Spica_2868 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat Spica_2868 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal Spica_2868 IPR013760 DNA topoisomerase, type IIA-like domain superfamily Spica_2868 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal Spica_2868 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily Spica_2868 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta Spica_2869 IPR011557 DNA gyrase, subunit B Spica_2869 IPR034160 DNA gyrase subunit B, TOPRIM domain Spica_2869 IPR006171 TOPRIM domain Spica_2869 IPR018522 DNA topoisomerase, type IIA, conserved site Spica_2869 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 Spica_2869 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal Spica_2869 IPR013760 DNA topoisomerase, type IIA-like domain superfamily Spica_2869 IPR001241 DNA topoisomerase, type IIA Spica_2869 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup Spica_2869 IPR020568 Ribosomal protein S5 domain 2-type fold Spica_2869 IPR036890 Histidine kinase/HSP90-like ATPase superfamily Spica_2869 IPR003594 Histidine kinase/HSP90-like ATPase Spica_2869 IPR002288 DNA gyrase B subunit, C-terminal Spica_R0030 IPR001539 Peptidase U32 Spica_R0030 IPR009000 Translation protein, beta-barrel domain superfamily